. 2000 Aug; 14(15):1837-51.

Wnt signaling and cancer

P Polakis 1 
  • PMID: 10921899
  •     1085 citations

No abstract available

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Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription.
S Chen, D C Guttridge, +5 authors, C Y Wang.
J Cell Biol, 2001 Jan 10; 152(1). PMID: 11149923    Free PMC article.
Highly Cited.
Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice.
Y Li, K Podsypanina, +4 authors, H E Varmus.
BMC Mol Biol, 2001 Feb 15; 2. PMID: 11178110    Free PMC article.
Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway.
M Brunori, M Malerba, H Kashiwazaki, R Iggo.
J Virol, 2001 Feb 27; 75(6). PMID: 11222711    Free PMC article.
Top-down morphogenesis of colorectal tumors.
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Proc Natl Acad Sci U S A, 2001 Feb 28; 98(5). PMID: 11226292    Free PMC article.
The establishment of Spemann's organizer and patterning of the vertebrate embryo.
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Nat Rev Genet, 2001 Mar 17; 1(3). PMID: 11252746    Free PMC article.
EGF receptor/Rolled MAP kinase signalling protects cells against activated Armadillo in the Drosophila eye.
M Freeman, M Bienz.
EMBO Rep, 2001 Mar 22; 2(2). PMID: 11258709    Free PMC article.
Naked cuticle targets dishevelled to antagonize Wnt signal transduction.
R Rousset, J A Mack, +5 authors, M P Scott.
Genes Dev, 2001 Mar 29; 15(6). PMID: 11274052    Free PMC article.
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd.
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Proc Natl Acad Sci U S A, 2001 Mar 29; 98(7). PMID: 11274398    Free PMC article.
Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta.
J Zavadil, M Bitzer, +5 authors, E P Bottinger.
Proc Natl Acad Sci U S A, 2001 Jun 08; 98(12). PMID: 11390996    Free PMC article.
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Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation.
S Persad, A A Troussard, +2 authors, S Dedhar.
J Cell Biol, 2001 Jun 13; 153(6). PMID: 11402061    Free PMC article.
Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway.
M Furuhashi, K Yagi, +6 authors, M Kato.
Mol Cell Biol, 2001 Jul 05; 21(15). PMID: 11438668    Free PMC article.
Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1.
W Tao, D Pennica, +2 authors, A J Levine.
Genes Dev, 2001 Jul 19; 15(14). PMID: 11459829    Free PMC article.
HMG box transcriptional repressor HBP1 maintains a proliferation barrier in differentiated liver tissue.
H H Shih, M Xiu, +4 authors, A S Yee.
Mol Cell Biol, 2001 Aug 04; 21(17). PMID: 11486012    Free PMC article.
Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1.
E M Sampson, Z K Haque, +5 authors, A S Yee.
EMBO J, 2001 Aug 14; 20(16). PMID: 11500377    Free PMC article.
Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2.
D T Dang, C S Mahatan, +2 authors, V W Yang.
Oncogene, 2001 Aug 25; 20(35). PMID: 11521200    Free PMC article.
Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation.
A Damalas, S Kahan, +2 authors, M Oren.
EMBO J, 2001 Sep 05; 20(17). PMID: 11532955    Free PMC article.
Protein kinase B phosphorylates AHNAK and regulates its subcellular localization.
J Sussman, D Stokoe, N Ossina, E Shtivelman.
J Cell Biol, 2001 Sep 06; 154(5). PMID: 11535620    Free PMC article.
GSK3 takes centre stage more than 20 years after its discovery.
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Biochem J, 2001 Sep 21; 359(Pt 1). PMID: 11563964    Free PMC article.
Highly Cited. Review.
E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity.
A Stockinger, A Eger, +2 authors, R Foisner.
J Cell Biol, 2001 Sep 21; 154(6). PMID: 11564756    Free PMC article.
Down-regulation of beta-catenin by activated p53.
E Sadot, B Geiger, M Oren, A Ben-Ze'ev.
Mol Cell Biol, 2001 Sep 21; 21(20). PMID: 11564862    Free PMC article.
Actin-dependent membrane association of the APC tumour suppressor in polarized mammalian epithelial cells.
R Rosin-Arbesfeld, G Ihrke, M Bienz.
EMBO J, 2001 Nov 02; 20(21). PMID: 11689433    Free PMC article.
SOX7 transcription factor: sequence, chromosomal localisation, expression, transactivation and interference with Wnt signalling.
W Takash, J Cañizares, +4 authors, P Berta.
Nucleic Acids Res, 2001 Nov 03; 29(21). PMID: 11691915    Free PMC article.
The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D1, and p16INK4A and is a region of low proliferation.
A Jung, M Schrauder, +6 authors, T Kirchner.
Am J Pathol, 2001 Nov 07; 159(5). PMID: 11696421    Free PMC article.
The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice.
K Tateishi, M Omata, K Tanaka, T Chiba.
J Cell Biol, 2001 Nov 07; 155(4). PMID: 11696557    Free PMC article.
COX-2 and cancer: a new approach to an old problem.
Y S Bakhle.
Br J Pharmacol, 2001 Nov 13; 134(6). PMID: 11704632    Free PMC article.
COL11A1 in FAP polyps and in sporadic colorectal tumors.
H Fischer, S Salahshor, +5 authors, A Lindblom.
BMC Cancer, 2001 Nov 15; 1. PMID: 11707154    Free PMC article.
Seven Wnt homologues in Drosophila: a case study of the developing tracheae.
M Llimargas, P A Lawrence.
Proc Natl Acad Sci U S A, 2001 Nov 22; 98(25). PMID: 11717401    Free PMC article.
Analysis of allelic imbalance in patients with colorectal cancer according to stage and presence of synchronous liver metastases.
J C Weber, A Schneider, +10 authors, D Jaeck.
Ann Surg, 2001 Dec 01; 234(6). PMID: 11729386    Free PMC article.
Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia.
A Rosenwald, A A Alizadeh, +16 authors, L M Staudt.
J Exp Med, 2001 Dec 26; 194(11). PMID: 11733578    Free PMC article.
Highly Cited.
Wnt signaling in breast cancer: have we come full circle?
A M Brown.
Breast Cancer Res, 2001 Dec 12; 3(6). PMID: 11737884    Free PMC article.
Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice.
W Hsu, R Shakya, F Costantini.
J Cell Biol, 2001 Dec 12; 155(6). PMID: 11739413    Free PMC article.
Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro.
A V Tutter, C J Fryer, K A Jones.
Genes Dev, 2001 Dec 26; 15(24). PMID: 11751639    Free PMC article.
The Wnts.
Jeffrey R Miller.
Genome Biol, 2002 Jan 25; 3(1). PMID: 11806834    Free PMC article.
Highly Cited. Review.
SFRP2 expression in rabbit myogenic progenitor cells and in adult skeletal muscles.
J M Levin, R A El Andalousi, +2 authors, F Bacou.
J Muscle Res Cell Motil, 2002 Jan 26; 22(4). PMID: 11808776
Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway.
Eek-hoon Jho, Tong Zhang, +3 authors, Frank Costantini.
Mol Cell Biol, 2002 Jan 26; 22(4). PMID: 11809808    Free PMC article.
Highly Cited.
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors.
Barbara Lustig, Boris Jerchow, +8 authors, Jürgen Behrens.
Mol Cell Biol, 2002 Jan 26; 22(4). PMID: 11809809    Free PMC article.
Highly Cited.
Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex.
Zhong-Hua Gao, Joni M Seeling, +2 authors, David M Virshup.
Proc Natl Acad Sci U S A, 2002 Jan 31; 99(3). PMID: 11818547    Free PMC article.
Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility.
Gerardo Morfini, Györgyi Szebenyi, +2 authors, Scott T Brady.
EMBO J, 2002 Feb 02; 21(3). PMID: 11823421    Free PMC article.
Highly Cited.
Caenorhabditis elegans unc-37/groucho interacts genetically with components of the transcriptional mediator complex.
Hong Zhang, Scott W Emmons.
Genetics, 2002 Feb 28; 160(2). PMID: 11861580    Free PMC article.
The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death.
Lars Grotewold, Ulrich Rüther.
EMBO J, 2002 Feb 28; 21(5). PMID: 11867524    Free PMC article.
Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila.
Shin-ichi Yanagawa, Yukihiro Matsuda, +4 authors, Akinori Ishimoto.
EMBO J, 2002 Apr 03; 21(7). PMID: 11927557    Free PMC article.
Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas.
Yali Zhai, Rong Wu, +6 authors, Kathleen R Cho.
Am J Pathol, 2002 Apr 12; 160(4). PMID: 11943708    Free PMC article.
A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions.
Philippe Marambaud, Junichi Shioi, +9 authors, Nikolaos K Robakis.
EMBO J, 2002 Apr 16; 21(8). PMID: 11953314    Free PMC article.
Highly Cited.
The cadherin-catenin adhesion system in signaling and cancer.
Maralice Conacci-Sorrell, Jacob Zhurinsky, Avri Ben-Ze'ev.
J Clin Invest, 2002 Apr 17; 109(8). PMID: 11956233    Free PMC article.
Highly Cited. Review.
Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis.
Zongbing You, Daniel Saims, +8 authors, Cun-Yu Wang.
J Cell Biol, 2002 May 01; 157(3). PMID: 11980918    Free PMC article.
beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds.
Sophia S Cheon, Alexander Y L Cheah, +4 authors, Benjamin A Alman.
Proc Natl Acad Sci U S A, 2002 May 02; 99(10). PMID: 11983872    Free PMC article.
Highly Cited.
Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway.
Sharon Amit, Ada Hatzubai, +5 authors, Irit Alkalay.
Genes Dev, 2002 May 10; 16(9). PMID: 12000790    Free PMC article.
Highly Cited.
Activation of Wnt signaling bypasses the requirement for RTK/Ras signaling during C. elegans vulval induction.
Julie E Gleason, Hendrik C Korswagen, David M Eisenmann.
Genes Dev, 2002 May 23; 16(10). PMID: 12023306    Free PMC article.
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation.
Timothy A Chan, Zhenghe Wang, +2 authors, Kenneth W Kinzler.
Proc Natl Acad Sci U S A, 2002 Jun 13; 99(12). PMID: 12060769    Free PMC article.
An analysis using the hobo genetic system reveals that combinatorial signaling by the Dpp and Wg pathways regulates dpp expression in leading edge cells of the dorsal ectoderm in Drosophila melanogaster.
S J Newfeld, N T Takaesu.
Genetics, 2002 Jun 20; 161(2). PMID: 12072465    Free PMC article.
Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon.
Christine B Anderson, Kristi L Neufeld, Raymond L White.
Proc Natl Acad Sci U S A, 2002 Jun 20; 99(13). PMID: 12072559    Free PMC article.
Opposing effects of Krüppel-like factor 4 (gut-enriched Krüppel-like factor) and Krüppel-like factor 5 (intestinal-enriched Krüppel-like factor) on the promoter of the Krüppel-like factor 4 gene.
Duyen T Dang, Weidong Zhao, +2 authors, Vincent W Yang.
Nucleic Acids Res, 2002 Jun 28; 30(13). PMID: 12087155    Free PMC article.
Endostatin is a potential inhibitor of Wnt signaling.
Jun-ichi Hanai, Joachim Gloy, +8 authors, Sergei Sokol.
J Cell Biol, 2002 Jul 31; 158(3). PMID: 12147676    Free PMC article.
Nr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesis.
Maralice E Conacci-Sorrell, Tamar Ben-Yedidia, +3 authors, Avri Ben-Ze'ev.
Genes Dev, 2002 Aug 17; 16(16). PMID: 12183361    Free PMC article.
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling.
Thomas Schwarz-Romond, Christian Asbrand, +6 authors, Walter Birchmeier.
Genes Dev, 2002 Aug 17; 16(16). PMID: 12183362    Free PMC article.
I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways.
Shuichi Kusano, Nancy Raab-Traub.
Mol Cell Biol, 2002 Aug 23; 22(18). PMID: 12192039    Free PMC article.
What can humans learn from flies about adenomatous polyposis coli?
Angela I M Barth, W James Nelson.
Bioessays, 2002 Sep 05; 24(9). PMID: 12210511    Free PMC article.
The ins and outs of APC and beta-catenin nuclear transport.
Beric R Henderson, Francois Fagotto.
EMBO Rep, 2002 Sep 12; 3(9). PMID: 12223464    Free PMC article.
A yeast model system for functional analysis of beta-catenin signaling.
Margaret S Lee, Karen A D'Amour, Jackie Papkoff.
J Cell Biol, 2002 Sep 18; 158(6). PMID: 12235124    Free PMC article.
Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor.
Hans R Widlund, Martin A Horstmann, +5 authors, David E Fisher.
J Cell Biol, 2002 Sep 18; 158(6). PMID: 12235125    Free PMC article.
Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma.
Rex C Haydon, Andrea Deyrup, +11 authors, Tong-Chuan He.
Int J Cancer, 2002 Oct 29; 102(4). PMID: 12402302    Free PMC article.
Proliferation, but not apoptosis, is associated with distinct beta-catenin expression patterns in non-small-cell lung carcinomas: relationship with adenomatous polyposis coli and G(1)-to S-phase cell-cycle regulators.
Athamassios Kotsinas, Konstantinos Evangelou, +2 authors, Vassilis G Gorgoulis.
Am J Pathol, 2002 Nov 05; 161(5). PMID: 12414510    Free PMC article.
Analysis of the beta-catenin/T cell factor signaling pathway in 36 gastrointestinal and liver cancer cells.
Tsuneo Ikenoue, Hideaki Ijichi, +8 authors, Masao Omata.
Jpn J Cancer Res, 2002 Dec 04; 93(11). PMID: 12460462    Free PMC article.
Craniopharyngiomas of adamantinomatous type harbor beta-catenin gene mutations.
Shigeki Sekine, Tatsuhiro Shibata, +5 authors, Setsuo Hirohashi.
Am J Pathol, 2002 Dec 06; 161(6). PMID: 12466115    Free PMC article.
The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling.
Tohru Ishitani, Satoshi Kishida, +7 authors, Kunihiro Matsumoto.
Mol Cell Biol, 2002 Dec 17; 23(1). PMID: 12482967    Free PMC article.
Highly Cited.
Expression of e-cadherin and beta-catenin in human esophageal squamous cell carcinoma: relationships with prognosis.
Xi-Jiang Zhao, Hui Li, +4 authors, Qing-Lai Feng.
World J Gastroenterol, 2003 Jan 18; 9(2). PMID: 12532436    Free PMC article.
Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.
Roderick H Dashwood.
J Biochem Mol Biol, 2003 Jan 25; 36(1). PMID: 12542973    Free PMC article.
Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex.
Rana Dajani, Elizabeth Fraser, +5 authors, Laurence H Pearl.
EMBO J, 2003 Jan 30; 22(3). PMID: 12554650    Free PMC article.
The role of the ubiquitination-proteasome pathway in breast cancer: use of mouse models for analyzing ubiquitination processes.
Sabrina Rossi, Massimo Loda.
Breast Cancer Res, 2003 Feb 01; 5(1). PMID: 12559040    Free PMC article.
IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf.
Chris Albanese, Kongming Wu, +13 authors, Richard G Pestell.
Mol Biol Cell, 2003 Feb 18; 14(2). PMID: 12589056    Free PMC article.
Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis.
Edward J Gunther, Susan E Moody, +5 authors, Lewis A Chodosh.
Genes Dev, 2003 Feb 26; 17(4). PMID: 12600942    Free PMC article.
Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription.
Rina Rosin-Arbesfeld, Adam Cliffe, Thomas Brabletz, Mariann Bienz.
EMBO J, 2003 Feb 28; 22(5). PMID: 12606575    Free PMC article.
Wnt1 and Wnt5a induce cyclin D1 expression through ErbB1 transactivation in HC11 mammary epithelial cells.
Gianluca Civenni, Thomas Holbro, Nancy E Hynes.
EMBO Rep, 2003 Mar 04; 4(2). PMID: 12612606    Free PMC article.
GSK-3: tricks of the trade for a multi-tasking kinase.
Bradley W Doble, James R Woodgett.
J Cell Sci, 2003 Mar 05; 116(Pt 7). PMID: 12615961    Free PMC article.
Highly Cited. Review.
Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo.
Barbara Murdoch, Kristin Chadwick, +5 authors, Mickie Bhatia.
Proc Natl Acad Sci U S A, 2003 Mar 11; 100(6). PMID: 12626754    Free PMC article.
Beta-catenin: a transforming actor on many stages.
Keiko Miyoshi, Lothar Hennighausen.
Breast Cancer Res, 2003 Mar 13; 5(2). PMID: 12631383    Free PMC article.
Is there a role for Notch signalling in human breast cancer?
Keith Brennan, Anthony M C Brown.
Breast Cancer Res, 2003 Mar 13; 5(2). PMID: 12631384    Free PMC article.
WISP-2 gene in human breast cancer: estrogen and progesterone inducible expression and regulation of tumor cell proliferation.
Snigdha Banerjee, Neela Saxena, +3 authors, Sushanta K Banerjee.
Neoplasia, 2003 Mar 28; 5(1). PMID: 12659671    Free PMC article.
Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun.
Carmen A Blum, Tomoko Tanaka, +5 authors, Roderick H Dashwood.
Mol Carcinog, 2003 Apr 02; 36(4). PMID: 12669311    Free PMC article.
Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the beta-catenin signaling activity.
Lan Zhou, Naili An, +10 authors, Tong-Chuan He.
Cancer Lett, 2003 Apr 23; 193(2). PMID: 12706873    Free PMC article.
Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis.
Marco Chilosi, Venerino Poletti, +11 authors, Claudio Doglioni.
Am J Pathol, 2003 Apr 23; 162(5). PMID: 12707032    Free PMC article.
Highly Cited.
Loss of expression of the WNT/beta-catenin-signaling pathway transcription factors lymphoid enhancer factor-1 (LEF-1) and T cell factor-1 (TCF-1) in a subset of peripheral T cell lymphomas.
David M Dorfman, Harvey A Greisman, Aliakbar Shahsafaei.
Am J Pathol, 2003 Apr 23; 162(5). PMID: 12707037    Free PMC article.
The Wnt signaling pathway and its role in tumor development.
B Lustig, J Behrens.
J Cancer Res Clin Oncol, 2003 Apr 23; 129(4). PMID: 12707770
Highly Cited. Review.
Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors.
Liang Schweizer, Harold Varmus.
BMC Cell Biol, 2003 May 06; 4. PMID: 12729465    Free PMC article.
Changing neighbours, changing behaviour: cell adhesion molecule-mediated signalling during tumour progression.
Gerhard Christofori.
EMBO J, 2003 May 14; 22(10). PMID: 12743026    Free PMC article.
A functional screen in human cells identifies UBF2 as an RNA polymerase II transcription factor that enhances the beta-catenin signaling pathway.
Dorre A Grueneberg, Lourdes Pablo, +3 authors, Jacqueline Papkoff.
Mol Cell Biol, 2003 May 16; 23(11). PMID: 12748295    Free PMC article.
Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice.
David Van Mater, Frank T Kolligs, Andrzej A Dlugosz, Eric R Fearon.
Genes Dev, 2003 May 21; 17(10). PMID: 12756226    Free PMC article.
Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, beta-catenin, and the phosphatase DEP-1/CD148.
Maria Grazia Lampugnani, Adriana Zanetti, +8 authors, Elisabetta Dejana.
J Cell Biol, 2003 May 29; 161(4). PMID: 12771128    Free PMC article.
Highly Cited.
E-cadherin involved in inactivation of WNT/beta-catenin signalling in urothelial carcinoma and normal urothelial cells.
I Thievessen, H-H Seifert, +2 authors, W A Schulz.
Br J Cancer, 2003 Jun 12; 88(12). PMID: 12799639    Free PMC article.
Regulation of the Wnt signaling pathway by disabled-2 (Dab2).
B A Hocevar, F Mou, +3 authors, P H Howe.
EMBO J, 2003 Jun 14; 22(12). PMID: 12805222    Free PMC article.
The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus manipulates the activity of glycogen synthase kinase-3beta.
Masahiro Fujimuro, S Diane Hayward.
J Virol, 2003 Jun 28; 77(14). PMID: 12829841    Free PMC article.
T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors.
Jennifer A Kennell, Erin E O'Leary, +2 authors, Ormond A MacDougald.
Mol Cell Biol, 2003 Jul 16; 23(15). PMID: 12861022    Free PMC article.
Expression of secreted frizzled-related protein 2 in a primary canine mammary tumor cell line: a candidate tumor marker for mammary tumor cells.
Jia-Lin Lee, Ching-Jin Chang, Ling-Ling Chueh, Chung-Tien Lin.
In Vitro Cell Dev Biol Anim, 2003 Jul 18; 39(5-6). PMID: 12866949
Elevated levels of beta-catenin and fibronectin in three-dimensional collagen cultures of Dupuytren's disease cells are regulated by tension in vitro.
Jeffrey C Howard, Vincenzo M Varallo, +4 authors, Bing Siang Gan.
BMC Musculoskelet Disord, 2003 Jul 18; 4. PMID: 12866952    Free PMC article.
A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor.
Guizhong Liu, Anna Bafico, Violaine K Harris, Stuart A Aaronson.
Mol Cell Biol, 2003 Aug 05; 23(16). PMID: 12897152    Free PMC article.
Breast cancer classification and prognosis based on gene expression profiles from a population-based study.
Christos Sotiriou, Soek-Ying Neo, +7 authors, Edison T Liu.
Proc Natl Acad Sci U S A, 2003 Aug 15; 100(18). PMID: 12917485    Free PMC article.
Highly Cited.
Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis.
C Niemann, A B Unden, +3 authors, F M Watt.
Proc Natl Acad Sci U S A, 2003 Aug 15; 100 Suppl 1. PMID: 12917489    Free PMC article.
Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb.
Natalia Soshnikova, Dietmar Zechner, +5 authors, Walter Birchmeier.
Genes Dev, 2003 Aug 19; 17(16). PMID: 12923052    Free PMC article.
Peroxisome-proliferator-activated receptor gamma suppresses Wnt/beta-catenin signalling during adipogenesis.
Marthe Moldes, Ying Zuo, +4 authors, Stephen R Farmer.
Biochem J, 2003 Sep 05; 376(Pt 3). PMID: 12954078    Free PMC article.
Highly Cited.
Unlocking the secrets of syndecans: transgenic organisms as a potential key.
Robert Bellin, Ishan Capila, +3 authors, Merton R Bernfield.
Glycoconj J, 2003 Sep 17; 19(4-5). PMID: 12975608
Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
Emmanuelle Passegué, Catriona H M Jamieson, Laurie E Ailles, Irving L Weissman.
Proc Natl Acad Sci U S A, 2003 Sep 25; 100 Suppl 1. PMID: 14504387    Free PMC article.
Highly Cited. Review.
Characterization of dysplastic aberrant crypt foci in the rat colon induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Masako Ochiai, Mitsunori Ushigome, +5 authors, Hitoshi Nakagama.
Am J Pathol, 2003 Sep 26; 163(4). PMID: 14507667    Free PMC article.
Wnt ligand expression in malignant melanoma: pilot study indicating correlation with histopathological features.
K Pham, T Milovanovic, +2 authors, R F Holcombe.
Mol Pathol, 2003 Sep 30; 56(5). PMID: 14514922    Free PMC article.
A protein knockdown strategy to study the function of beta-catenin in tumorigenesis.
Feng Cong, Jianxuan Zhang, +2 authors, Harold Varmus.
BMC Mol Biol, 2003 Oct 01; 4. PMID: 14516475    Free PMC article.
Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription.
Susana Miravet, José Piedra, +4 authors, Antonio García de Herreros.
Mol Cell Biol, 2003 Oct 01; 23(20). PMID: 14517306    Free PMC article.
Beta-catenin mutations are frequent in calcifying odontogenic cysts, but rare in ameloblastomas.
Shigeki Sekine, Sunao Sato, +6 authors, Setsuo Hirohashi.
Am J Pathol, 2003 Oct 28; 163(5). PMID: 14578169    Free PMC article.
Epstein-Barr virus latent membrane protein 2A activates beta-catenin signaling in epithelial cells.
J A Morrison, A J Klingelhutz, N Raab-Traub.
J Virol, 2003 Oct 29; 77(22). PMID: 14581564    Free PMC article.
Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex.
Yi Xing, Wilson K Clements, David Kimelman, Wenqing Xu.
Genes Dev, 2003 Nov 06; 17(22). PMID: 14600025    Free PMC article.
A core function for p120-catenin in cadherin turnover.
Michael A Davis, Renee C Ireton, Albert B Reynolds.
J Cell Biol, 2003 Nov 12; 163(3). PMID: 14610055    Free PMC article.
Highly Cited.
Requirement for a nuclear function of beta-catenin in Wnt signaling.
Feng Cong, Liang Schweizer, Mario Chamorro, Harold Varmus.
Mol Cell Biol, 2003 Nov 13; 23(23). PMID: 14612392    Free PMC article.
Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK.
Maralice Conacci-Sorrell, Inbal Simcha, +3 authors, Avri Ben-Ze'ev.
J Cell Biol, 2003 Nov 19; 163(4). PMID: 14623871    Free PMC article.
Highly Cited.
Alterations of beta-catenin pathway in non-melanoma skin tumors: loss of alpha-ABC nuclear reactivity correlates with the presence of beta-catenin gene mutation.
Claudio Doglioni, Sara Piccinin, +7 authors, Roberta Maestro.
Am J Pathol, 2003 Nov 25; 163(6). PMID: 14633602    Free PMC article.
Helix-loop-helix proteins in mammary gland development and breast cancer.
Pierre-Yves Desprez, Tomoki Sumida, Jean-Philippe Coppé.
J Mammary Gland Biol Neoplasia, 2003 Nov 26; 8(2). PMID: 14635797
Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC.
Rebecca A Green, Kenneth B Kaplan.
J Cell Biol, 2003 Dec 10; 163(5). PMID: 14662741    Free PMC article.
Epstein-Barr virus activates beta-catenin in type III latently infected B lymphocyte lines: association with deubiquitinating enzymes.
Julia Shackelford, Christopher Maier, Joseph S Pagano.
Proc Natl Acad Sci U S A, 2003 Dec 10; 100(26). PMID: 14663138    Free PMC article.
Role of APC and DNA mismatch repair genes in the development of colorectal cancers.
Satya Narayan, Deodutta Roy.
Mol Cancer, 2003 Dec 16; 2. PMID: 14672538    Free PMC article.
Regulation of COX-2 transcription in a colon cancer cell line by Pontin52/TIP49a.
Mary L Carlson, Ellen T Wilson, Stephen M Prescott.
Mol Cancer, 2003 Dec 17; 2. PMID: 14675489    Free PMC article.
Physiological roles of glycogen synthase kinase-3: potential as a therapeutic target for diabetes and other disorders.
J R Woodgett.
Curr Drug Targets Immune Endocr Metabol Disord, 2003 Dec 20; 3(4). PMID: 14683459    Free PMC article.
A wingless flight.
Xiang Yu.
PLoS Biol, 2003 Dec 24; 1(3). PMID: 14691532    Free PMC article.
A mouse model of uterine leiomyosarcoma.
Katerina Politi, Matthias Szabolcs, +3 authors, Argiris Efstratiadis.
Am J Pathol, 2003 Dec 26; 164(1). PMID: 14695345    Free PMC article.
Morphogenesis of chicken liver: identification of localized growth zones and the role of beta-catenin/Wnt in size regulation.
Sanong Suksaweang, Chih-Min Lin, +3 authors, Cheng-Ming Chuong.
Dev Biol, 2004 Jan 20; 266(1). PMID: 14729482    Free PMC article.
Signalling activity of beta-catenin targeted to different subcellular compartments.
Thilo Hagen, Jaswinder K Sethi, Neale Foxwell, Antonio Vidal-Puig.
Biochem J, 2004 Jan 22; 379(Pt 2). PMID: 14733614    Free PMC article.
Casein kinase Iepsilon modulates the signaling specificities of dishevelled.
Feng Cong, Liang Schweizer, Harold Varmus.
Mol Cell Biol, 2004 Feb 18; 24(5). PMID: 14966280    Free PMC article.
Biochemical characterization of the Drosophila wingless signaling pathway based on RNA interference.
Hiroko Matsubayashi, Sonoka Sese, +4 authors, Shin-ichi Yanagawa.
Mol Cell Biol, 2004 Feb 18; 24(5). PMID: 14966281    Free PMC article.
Frequent loss of the AXIN1 locus but absence of AXIN1 gene mutations in adenocarcinomas of the gastro-oesophageal junction with nuclear beta-catenin expression.
L B Koppert, A W van der Velden, +5 authors, W N M Dinjens.
Br J Cancer, 2004 Feb 19; 90(4). PMID: 14970870    Free PMC article.
Wnt signalling via the epidermal growth factor receptor: a role in breast cancer?
Elizabeth A Musgrove.
Breast Cancer Res, 2004 Feb 26; 6(2). PMID: 14979908    Free PMC article.
Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin.
Feng Cong, Harold Varmus.
Proc Natl Acad Sci U S A, 2004 Feb 26; 101(9). PMID: 14981260    Free PMC article.
Manipulation of glycogen-synthase kinase-3 activity in KSHV-associated cancers.
Masahiro Fujimuro, S Diane Hayward.
J Mol Med (Berl), 2004 Apr 03; 82(4). PMID: 14991150
Convergence of Wnt, beta-catenin, and cadherin pathways.
W James Nelson, Roel Nusse.
Science, 2004 Mar 06; 303(5663). PMID: 15001769    Free PMC article.
Highly Cited. Review.
Deoxycholic acid activates beta-catenin signaling pathway and increases colon cell cancer growth and invasiveness.
Rama Pai, Andrzej S Tarnawski, Teresa Tran.
Mol Biol Cell, 2004 Mar 09; 15(5). PMID: 15004225    Free PMC article.
The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells.
Bob Y Liu, Sean P McDermott, Shariq S Khwaja, Caroline M Alexander.
Proc Natl Acad Sci U S A, 2004 Mar 17; 101(12). PMID: 15020770    Free PMC article.
Highly Cited.
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.
Carsten Müller-Tidow, Björn Steffen, +13 authors, Hubert Serve.
Mol Cell Biol, 2004 Mar 17; 24(7). PMID: 15024077    Free PMC article.
HBP1 repression of the p47phox gene: cell cycle regulation via the NADPH oxidase.
Stephen P Berasi, Mei Xiu, Amy S Yee, K Eric Paulson.
Mol Cell Biol, 2004 Mar 17; 24(7). PMID: 15024088    Free PMC article.
PPAR gamma signaling exacerbates mammary gland tumor development.
Enrique Saez, John Rosenfeld, +7 authors, Ronald M Evans.
Genes Dev, 2004 Mar 24; 18(5). PMID: 15037548    Free PMC article.
Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos.
Alex Gregorieff, Rudolf Grosschedl, Hans Clevers.
EMBO J, 2004 Apr 02; 23(8). PMID: 15057272    Free PMC article.
Acetylation of beta-catenin by p300 regulates beta-catenin-Tcf4 interaction.
Laurence Lévy, Yu Wei, +4 authors, Christine Neuveut.
Mol Cell Biol, 2004 Apr 03; 24(8). PMID: 15060161    Free PMC article.
Phosphorylation and ubiquitination of oncogenic mutants of beta-catenin containing substitutions at Asp32.
Mohamed Al-Fageeh, Qingjie Li, +2 authors, Roderick H Dashwood.
Oncogene, 2004 Apr 06; 23(28). PMID: 15064718    Free PMC article.
Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins.
Keith Brennan, José M Gonzalez-Sancho, +2 authors, Anthony M C Brown.
Oncogene, 2004 Apr 06; 23(28). PMID: 15064719    Free PMC article.
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells.
Patrick W B Derksen, Esther Tjin, +10 authors, Steven T Pals.
Proc Natl Acad Sci U S A, 2004 Apr 07; 101(16). PMID: 15067127    Free PMC article.
Highly Cited.
A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells.
Biao He, Liang You, +5 authors, David M Jablons.
Neoplasia, 2004 Apr 08; 6(1). PMID: 15068666    Free PMC article.
Wnt11 signaling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells.
Lillian Ouko, Thomas R Ziegler, +2 authors, Vincent W Yang.
J Biol Chem, 2004 Apr 16; 279(25). PMID: 15084607    Free PMC article.
Groucho oligomerization is required for repression in vivo.
Haiyun Song, Peleg Hasson, Ze'ev Paroush, Albert J Courey.
Mol Cell Biol, 2004 May 04; 24(10). PMID: 15121853    Free PMC article.
Identification of Wnt responsive genes using a murine mammary epithelial cell line model system.
Lisa Taneyhill, Diane Pennica.
BMC Dev Biol, 2004 May 14; 4. PMID: 15140269    Free PMC article.
Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin.
José M González-Sancho, Keith R Brennan, Leslie A Castelo-Soccio, Anthony M C Brown.
Mol Cell Biol, 2004 May 15; 24(11). PMID: 15143170    Free PMC article.
Functional studies of shaggy/glycogen synthase kinase 3 phosphorylation sites in Drosophila melanogaster.
Deppie Papadopoulou, Michele Wolfe Bianchi, Marc Bourouis.
Mol Cell Biol, 2004 May 15; 24(11). PMID: 15143183    Free PMC article.
Targeting multiple signal transduction pathways through inhibition of Hsp90.
Hong Zhang, Francis Burrows.
J Mol Med (Berl), 2004 May 29; 82(8). PMID: 15168026
Highly Cited. Review.
VE-cadherin expression and clustering maintain low levels of survivin in endothelial cells.
Monica Iurlaro, Fabio Demontis, +10 authors, Elisabetta Dejana.
Am J Pathol, 2004 Jun 25; 165(1). PMID: 15215174    Free PMC article.
Antisense Tcf inhibits the neoplastic growth of liver cancer cells.
Ying Jiang, Xin-Da Zhou, +6 authors, Xin Wu.
J Cancer Res Clin Oncol, 2004 Jun 29; 130(11). PMID: 15221470
Subcellular localization of frizzled receptors, mediated by their cytoplasmic tails, regulates signaling pathway specificity.
Jun Wu, Thomas J Klein, Marek Mlodzik.
PLoS Biol, 2004 Jul 15; 2(7). PMID: 15252441    Free PMC article.
Wnt proteins in mammary development and cancer.
Keith R Brennan, Anthony M C Brown.
J Mammary Gland Biol Neoplasia, 2004 Aug 10; 9(2). PMID: 15300008
WISP-1 is an osteoblastic regulator expressed during skeletal development and fracture repair.
Dorothy M French, Raji J Kaul, +5 authors, Luc Desnoyers.
Am J Pathol, 2004 Aug 28; 165(3). PMID: 15331410    Free PMC article.
Activator protein 2alpha associates with adenomatous polyposis coli/beta-catenin and Inhibits beta-catenin/T-cell factor transcriptional activity in colorectal cancer cells.
Qingjie Li, Roderick H Dashwood.
J Biol Chem, 2004 Aug 28; 279(44). PMID: 15331612    Free PMC article.
Curcumin, a multi-functional chemopreventive agent, blocks growth of colon cancer cells by targeting beta-catenin-mediated transactivation and cell-cell adhesion pathways.
Satya Narayan.
J Mol Histol, 2004 Sep 02; 35(3). PMID: 15339049
Cellular FLIP inhibits beta-catenin ubiquitylation and enhances Wnt signaling.
Mikihiko Naito, Ryohei Katayama, +11 authors, Takashi Tsuruo.
Mol Cell Biol, 2004 Sep 16; 24(19). PMID: 15367663    Free PMC article.
beta-catenin-dependent and -independent effects of DeltaN-plakoglobin on epidermal growth and differentiation.
J Teulière, M M Faraldo, +4 authors, M A Glukhova.
Mol Cell Biol, 2004 Sep 16; 24(19). PMID: 15367683    Free PMC article.
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.
Felix H Brembeck, Thomas Schwarz-Romond, +3 authors, Walter Birchmeier.
Genes Dev, 2004 Sep 17; 18(18). PMID: 15371335    Free PMC article.
Highly Cited.
Intracellular shuttling of a Drosophila APC tumour suppressor homolog.
Adam Cliffe, Julius Mieszczanek, Mariann Bienz.
BMC Cell Biol, 2004 Oct 02; 5. PMID: 15458577    Free PMC article.
Accumulation of cytoplasmic beta-catenin and nuclear glycogen synthase kinase 3beta in Epstein-Barr virus-infected cells.
David N Everly, Shuichi Kusano, Nancy Raab-Traub.
J Virol, 2004 Oct 14; 78(21). PMID: 15479806    Free PMC article.
ARIA, an Arabidopsis arm repeat protein interacting with a transcriptional regulator of abscisic acid-responsive gene expression, is a novel abscisic acid signaling component.
Sunmi Kim, Hyung-in Choi, +3 authors, Soo Young Kim.
Plant Physiol, 2004 Nov 02; 136(3). PMID: 15516505    Free PMC article.
Immunolocalization of protein 4.1B/DAL-1 during neoplastic transformation of mouse and human intestinal epithelium.
Nobuhiko Ohno, Nobuo Terada, +5 authors, Shinichi Ohno.
Histochem Cell Biol, 2004 Nov 02; 122(6). PMID: 15517334
CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors.
Chi-Ming Li, Connie E Kim, +10 authors, Benjamin Tycko.
Am J Pathol, 2004 Dec 08; 165(6). PMID: 15579438    Free PMC article.
FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development.
Mario N Chamorro, Donald R Schwartz, +3 authors, Harold E Varmus.
EMBO J, 2004 Dec 14; 24(1). PMID: 15592430    Free PMC article.
Colocalization of APC and DLG at the tips of cellular protrusions in cultured epithelial cells and its dependency on cytoskeletons.
Akiko Iizuka-Kogo, Atsushi Shimomura, Takao Senda.
Histochem Cell Biol, 2004 Dec 21; 123(1). PMID: 15609045
Receptor and secreted targets of Wnt-1/beta-catenin signalling in mouse mammary epithelial cells.
Paraic A Kenny, Tariq Enver, Alan Ashworth.
BMC Cancer, 2005 Jan 12; 5. PMID: 15642117    Free PMC article.
Exon 3 beta-catenin mutations are specifically associated with colorectal carcinomas in hereditary non-polyposis colorectal cancer syndrome.
V Johnson, E Volikos, +10 authors, A R J Silver.
Gut, 2005 Jan 14; 54(2). PMID: 15647192    Free PMC article.
Desmosomal cadherin misexpression alters beta-catenin stability and epidermal differentiation.
Matthew J Hardman, Ke Liu, +4 authors, Carolyn Byrne.
Mol Cell Biol, 2005 Jan 20; 25(3). PMID: 15657425    Free PMC article.
Redefining the subcellular location and transport of APC: new insights using a panel of antibodies.
Mariana Brocardo, Inke S Näthke, Beric R Henderson.
EMBO Rep, 2005 Jan 29; 6(2). PMID: 15678162    Free PMC article.
Roles of the ITAM and PY motifs of Epstein-Barr virus latent membrane protein 2A in the inhibition of epithelial cell differentiation and activation of {beta}-catenin signaling.
Jennifer A Morrison, Nancy Raab-Traub.
J Virol, 2005 Feb 01; 79(4). PMID: 15681438    Free PMC article.
PR72, a novel regulator of Wnt signaling required for Naked cuticle function.
Menno P Creyghton, Giulietta Roël, +4 authors, René Bernards.
Genes Dev, 2005 Feb 03; 19(3). PMID: 15687260    Free PMC article.
Cancer/testis antigens and gametogenesis: a review and "brain-storming" session.
Martins Kalejs, Jekaterina Erenpreisa.
Cancer Cell Int, 2005 Feb 18; 5(1). PMID: 15715909    Free PMC article.
L1, a novel target of beta-catenin signaling, transforms cells and is expressed at the invasive front of colon cancers.
Nancy Gavert, Maralice Conacci-Sorrell, +4 authors, Avri Ben-Ze'ev.
J Cell Biol, 2005 Feb 18; 168(4). PMID: 15716380    Free PMC article.
Highly Cited.
The links between axin and carcinogenesis.
S Salahshor, J R Woodgett.
J Clin Pathol, 2005 Mar 01; 58(3). PMID: 15735151    Free PMC article.
Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity.
Penny Hayward, Keith Brennan, +4 authors, Alfonso Martinez Arias.
Development, 2005 Mar 18; 132(8). PMID: 15772135    Free PMC article.
Expression of cell adhesion molecules in oesophageal carcinoma and its prognostic value.
K S Nair, R Naidoo, R Chetty.
J Clin Pathol, 2005 Mar 26; 58(4). PMID: 15790695    Free PMC article.
Hepatitis C virus NS5A-mediated activation of phosphoinositide 3-kinase results in stabilization of cellular beta-catenin and stimulation of beta-catenin-responsive transcription.
Andrew Street, Andrew Macdonald, Christopher McCormick, Mark Harris.
J Virol, 2005 Mar 30; 79(8). PMID: 15795286    Free PMC article.
Genetic and epigenetic changes of components affecting the WNT pathway in colorectal carcinomas stratified by microsatellite instability.
Lin Thorstensen, Guro E Lind, +4 authors, Ragnhild A Lothe.
Neoplasia, 2005 Apr 02; 7(2). PMID: 15802015    Free PMC article.
Beta-catenin up-regulates the expression of cyclinD1, c-myc and MMP-7 in human pancreatic cancer: relationships with carcinogenesis and metastasis.
Yu-Jun Li, Zhi-Min Wei, Yun-Xiao Meng, Xiang-Rui Ji.
World J Gastroenterol, 2005 Apr 06; 11(14). PMID: 15810077    Free PMC article.
The mechanism of endogenous receptor activation functionally distinguishes prototype canonical and noncanonical Wnts.
Guizhong Liu, Anna Bafico, Stuart A Aaronson.
Mol Cell Biol, 2005 Apr 16; 25(9). PMID: 15831454    Free PMC article.
G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathway.
Ming Yang, Wendy W Zhong, +4 authors, Songzhu An.
Proc Natl Acad Sci U S A, 2005 Apr 20; 102(17). PMID: 15837931    Free PMC article.
The human D-glucuronyl C5-epimerase gene is transcriptionally activated through the beta-catenin-TCF4 pathway.
Giancarlo Ghiselli, Amit Agrawal.
Biochem J, 2005 Apr 28; 390(Pt 2). PMID: 15853773    Free PMC article.
Platelet-activating factor regulates cadherin-catenin adhesion system expression and beta-catenin phosphorylation during Kaposi's sarcoma cell motility.
Mariarosaria Boccellino, Giovanni Camussi, +4 authors, Lucio Quagliuolo.
Am J Pathol, 2005 Apr 28; 166(5). PMID: 15855650    Free PMC article.
Association of Csk to VE-cadherin and inhibition of cell proliferation.
Ulf Baumeister, Ruth Funke, +3 authors, Dietmar Vestweber.
EMBO J, 2005 Apr 30; 24(9). PMID: 15861137    Free PMC article.
Cell adhesion and signal transduction in cancer. Conference on cadherins, catenins and cancer.
Walter Birchmeier.
EMBO Rep, 2005 May 03; 6(5). PMID: 15864290    Free PMC article.
Wnts induce migration and invasion of myeloma plasma cells.
Ya-Wei Qiang, Katie Walsh, +5 authors, Stuart Rudikoff.
Blood, 2005 May 12; 106(5). PMID: 15886323    Free PMC article.
Mouse axin and axin2/conductin proteins are functionally equivalent in vivo.
Ian V Chia, Frank Costantini.
Mol Cell Biol, 2005 May 19; 25(11). PMID: 15899843    Free PMC article.
HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation.
C Jung, R-S Kim, +6 authors, C Kao.
Br J Cancer, 2005 Jun 02; 92(12). PMID: 15928669    Free PMC article.
Similarities and differences between the Wnt and reelin pathways in the forming brain.
Orly Reiner, Tamar Sapir.
Mol Neurobiol, 2005 Jun 15; 31(1-3). PMID: 15953816
Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation.
Nathalie L Chevallier, Salvador Soriano, +3 authors, Edward H Koo.
Am J Pathol, 2005 Jun 24; 167(1). PMID: 15972961    Free PMC article.
Beta-catenin mutations in craniopharyngiomas and pituitary adenomas.
Eftychia Oikonomou, Diele C Barreto, +3 authors, Eric F Adams.
J Neurooncol, 2005 Jun 28; 73(3). PMID: 15980970
Infrequent mutation of APC, AXIN1, and GSK3B in human pituitary adenomas with abnormal accumulation of CTNNB1.
Chunlan Sun, Takashi Yamato, +3 authors, Akira Horii.
J Neurooncol, 2005 Jun 28; 73(2). PMID: 15981102
Epidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liver.
Xinping Tan, Udayan Apte, +7 authors, Satdarshan P S Monga.
Gastroenterology, 2005 Jul 14; 129(1). PMID: 16012954    Free PMC article.
Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate.
Wan-Mohaiza Dashwood, Orianna Carter, +2 authors, Roderick H Dashwood.
Mutat Res, 2005 Aug 02; 591(1-2). PMID: 16054165    Free PMC article.
Wnt signaling drives WRM-1/beta-catenin asymmetries in early C. elegans embryos.
Kuniaki Nakamura, Soyoung Kim, +6 authors, Craig C Mello.
Genes Dev, 2005 Aug 04; 19(15). PMID: 16077004    Free PMC article.
An internal ribosome entry site mediates translation of lymphoid enhancer factor-1.
Judith Jimenez, Gwendolyn M Jang, Bert L Semler, Marian L Waterman.
RNA, 2005 Aug 27; 11(9). PMID: 16120831    Free PMC article.
Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability.
Geo Serban, Zen Kouchi, +4 authors, Nikolaos K Robakis.
J Biol Chem, 2005 Aug 30; 280(43). PMID: 16126725    Free PMC article.
Frequent loss of membranous E-cadherin in gastric cancers: A cross-talk with Wnt in determining the fate of beta-catenin.
Xiao-Xin Cheng, Zi-Chuang Wang, +6 authors, Hong Li.
Clin Exp Metastasis, 2005 Sep 01; 22(1). PMID: 16132582
Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization.
Sandrine Etienne-Manneville, Jean-Baptiste Manneville, +2 authors, Alan Hall.
J Cell Biol, 2005 Sep 15; 170(6). PMID: 16157700    Free PMC article.
Highly Cited.
A subset of high-grade pulmonary neuroendocrine carcinomas shows up-regulation of matrix metalloproteinase-7 associated with nuclear beta-catenin immunoreactivity, independent of EGFR and HER-2 gene amplification or expression.
Giuseppe Pelosi, Aldo Scarpa, +7 authors, Giuseppe Viale.
Virchows Arch, 2005 Sep 15; 447(6). PMID: 16158183
Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination.
Shin-ichiro Hino, Chie Tanji, Keiichi I Nakayama, Akira Kikuchi.
Mol Cell Biol, 2005 Oct 04; 25(20). PMID: 16199882    Free PMC article.
Highly Cited.
Immediate and delayed effects of E-cadherin inhibition on gene regulation and cell motility in human epidermoid carcinoma cells.
Henriette Andersen, Jakob Mejlvang, +6 authors, Eugene Tulchinsky.
Mol Cell Biol, 2005 Oct 04; 25(20). PMID: 16199889    Free PMC article.
Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors.
Rajan Singh, Jorge N Artaza, +4 authors, Shalender Bhasin.
Endocrinology, 2005 Oct 08; 147(1). PMID: 16210377    Free PMC article.
Highly Cited.
Gli1, downregulated in colorectal cancers, inhibits proliferation of colon cancer cells involving Wnt signalling activation.
T Akiyoshi, M Nakamura, +5 authors, M Katano.
Gut, 2005 Nov 22; 55(7). PMID: 16299030    Free PMC article.
RanBP3 enhances nuclear export of active (beta)-catenin independently of CRM1.
Jolita Hendriksen, Francois Fagotto, +3 authors, Maarten Fornerod.
J Cell Biol, 2005 Nov 30; 171(5). PMID: 16314428    Free PMC article.
Anti-proliferative effect of horehound leaf and wild cherry bark extracts on human colorectal cancer cells.
Kiyoshi Yamaguchi, Jason L Liggett, Nam-Cheol Kim, Seung Joon Baek.
Oncol Rep, 2005 Dec 06; 15(1). PMID: 16328068    Free PMC article.
A role for CK2alpha/beta in Xenopus early embryonic development.
Isabel Dominguez, Junko Mizuno, +3 authors, David C Seldin.
Mol Cell Biochem, 2005 Dec 14; 274(1-2). PMID: 16342412
Up-regulation of beta-catenin by a viral oncogene correlates with inhibition of the seven in absentia homolog 1 in B lymphoma cells.
Kyung Lib Jang, Julia Shackelford, So Young Seo, Joseph S Pagano.
Proc Natl Acad Sci U S A, 2005 Dec 14; 102(51). PMID: 16344472    Free PMC article.
Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction.
Shao-Yong Chen, Gerburg Wulf, +3 authors, Steven P Balk.
Mol Cell Biol, 2006 Jan 24; 26(3). PMID: 16428447    Free PMC article.
E-cadherin in gastric cancer.
Annie On On Chan.
World J Gastroenterol, 2006 Feb 17; 12(2). PMID: 16482618    Free PMC article.
Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism.
Ayyakannu Ayyanan, Gianluca Civenni, +8 authors, Cathrin Brisken.
Proc Natl Acad Sci U S A, 2006 Feb 28; 103(10). PMID: 16501043    Free PMC article.
Highly Cited.
Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression.
Wen Zhang, Xi Chen, +8 authors, Chunming Liu.
Mol Cell Biol, 2006 Mar 02; 26(6). PMID: 16507986    Free PMC article.
Solid-pseudopapillary neoplasms of the pancreas in men and women: do they differ?
Yu Takahashi, Nobuyoshi Hiraoka, +5 authors, Setsuo Hirohashi.
Virchows Arch, 2006 Mar 09; 448(5). PMID: 16523258
Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1.
Katsuhiro Kita, Torsten Wittmann, Inke S Näthke, Clare M Waterman-Storer.
Mol Biol Cell, 2006 Mar 10; 17(5). PMID: 16525027    Free PMC article.
Activation of the canonical wingless/T-cell factor signaling pathway promotes invasive differentiation of human trophoblast.
Jürgen Pollheimer, Thomas Loregger, +6 authors, Martin Knöfler.
Am J Pathol, 2006 Mar 28; 168(4). PMID: 16565489    Free PMC article.
PR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticle.
Menno P Creyghton, Giulietta Roël, +3 authors, René Bernards.
Proc Natl Acad Sci U S A, 2006 Mar 29; 103(14). PMID: 16567647    Free PMC article.
Thyroid hormone receptor alpha1 directly controls transcription of the beta-catenin gene in intestinal epithelial cells.
Michelina Plateroti, Elsa Kress, Jun Ichirou Mori, Jacques Samarut.
Mol Cell Biol, 2006 Apr 04; 26(8). PMID: 16581794    Free PMC article.
Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.
Wei Liu, Hongliang Rui, +10 authors, Sheng-Cai Lin.
EMBO J, 2006 Apr 08; 25(8). PMID: 16601693    Free PMC article.
Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context.
Amanda J Mikels, Roel Nusse.
PLoS Biol, 2006 Apr 11; 4(4). PMID: 16602827    Free PMC article.
Highly Cited.
Over-expressed estrogen receptor-alpha up-regulates hTNF-alpha gene expression and down-regulates beta-catenin signaling activity to induce the apoptosis and inhibit proliferation of LoVo colon cancer cells.
Hsi-Hsien Hsu, Sue-Fei Cheng, +8 authors, Chih-Yang Huang.
Mol Cell Biochem, 2006 Apr 22; 289(1-2). PMID: 16628468
Protocadherin-PC promotes androgen-independent prostate cancer cell growth.
Stephane Terry, Luis Queires, +7 authors, Francis Vacherot.
Prostate, 2006 Apr 26; 66(10). PMID: 16637074    Free PMC article.
The Wnt-dependent signaling pathways as target in oncology drug discovery.
Nico Janssens, Michel Janicot, Tim Perera.
Invest New Drugs, 2006 May 10; 24(4). PMID: 16683072    Free PMC article.
Wnt/beta-catenin signaling pathway is active in pancreatic development of rat embryo.
Qi-Ming Wang, Ye Zhang, +2 authors, Hui-Jun Yang.
World J Gastroenterol, 2006 May 12; 12(16). PMID: 16688812    Free PMC article.
C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila.
Ming Fang, Jiong Li, +3 authors, Ken M Cadigan.
EMBO J, 2006 May 20; 25(12). PMID: 16710294    Free PMC article.
Wnt expression and canonical Wnt signaling in human bone marrow B lymphopoiesis.
Guri Døsen, Ellen Tenstad, +3 authors, Edith Rian.
BMC Immunol, 2006 Jul 01; 7. PMID: 16808837    Free PMC article.
Wnt activation and alternative promoter repression of LEF1 in colon cancer.
Tony W-H Li, Ju-Hui T Ting, +3 authors, Marian L Waterman.
Mol Cell Biol, 2006 Jul 01; 26(14). PMID: 16809766    Free PMC article.
Breast cancer, stem cells and prospects for therapy.
Magnus D Lynch, Massimiliano Cariati, Anand D Purushotham.
Breast Cancer Res, 2006 Jul 13; 8(3). PMID: 16834766    Free PMC article.
The canonical Wnt signalling pathway and its APC partner in colon cancer development.
Jean Schneikert, Jürgen Behrens.
Gut, 2006 Jul 15; 56(3). PMID: 16840506    Free PMC article.
Priming-dependent phosphorylation and regulation of the tumor suppressor pVHL by glycogen synthase kinase 3.
Alexander Hergovich, Joanna Lisztwan, +3 authors, Wilhelm Krek.
Mol Cell Biol, 2006 Jul 19; 26(15). PMID: 16847331    Free PMC article.
Functional interaction between peroxisome proliferator-activated receptor gamma and beta-catenin.
Jiajian Liu, Hong Wang, Ying Zuo, Stephen R Farmer.
Mol Cell Biol, 2006 Jul 19; 26(15). PMID: 16847334    Free PMC article.
Activated hepatic stellate cells induce tumor progression of neoplastic hepatocytes in a TGF-beta dependent fashion.
M Mikula, V Proell, A N M Fischer, W Mikulits.
J Cell Physiol, 2006 Aug 03; 209(2). PMID: 16883581    Free PMC article.
Human T-cell leukemia virus type 1 tax dysregulates beta-catenin signaling.
Mariko Tomita, Akira Kikuchi, +2 authors, Naoki Mori.
J Virol, 2006 Aug 22; 80(21). PMID: 16920823    Free PMC article.
Leukemia stem cells.
Ling Luo, Zhong Chao Han.
Int J Hematol, 2006 Aug 24; 84(2). PMID: 16926133
Dual roles for adenomatous polyposis coli in regulating retinoic acid biosynthesis and Wnt during ocular development.
Lincoln D Nadauld, Stephanie Chidester, +8 authors, David A Jones.
Proc Natl Acad Sci U S A, 2006 Aug 30; 103(36). PMID: 16938888    Free PMC article.
Wnt expression is not correlated with beta-catenin dysregulation in Dupuytren's Disease.
David B O'Gorman, Yan Wu, +2 authors, Bing Siang Gan.
J Negat Results Biomed, 2006 Sep 01; 5. PMID: 16942611    Free PMC article.
Diseases of Wnt signaling.
Mark L Johnson, Nalini Rajamannan.
Rev Endocr Metab Disord, 2006 Sep 01; 7(1-2). PMID: 16944325    Free PMC article.
Switch of cadherin expression from E- to N-type during the activation of rat hepatic stellate cells.
Young-Suk Lim, Han Chu Lee, Hyo-Suk Lee.
Histochem Cell Biol, 2006 Sep 07; 127(2). PMID: 16955247
KLHL1/MRP2 mediates neurite outgrowth in a glycogen synthase kinase 3beta-dependent manner.
Seyha Seng, Hava Karsenty Avraham, +2 authors, Shalom Avraham.
Mol Cell Biol, 2006 Sep 20; 26(22). PMID: 16982692    Free PMC article.
The von Hippel-Lindau tumor suppressor gene product represses oncogenic beta-catenin signaling in renal carcinoma cells.
Benedetta Peruzzi, Gagani Athauda, Donald P Bottaro.
Proc Natl Acad Sci U S A, 2006 Sep 20; 103(39). PMID: 16983094    Free PMC article.
LZTS2 is a novel beta-catenin-interacting protein and regulates the nuclear export of beta-catenin.
Gregory Thyssen, Tzu-Huey Li, +3 authors, Zijie Sun.
Mol Cell Biol, 2006 Sep 27; 26(23). PMID: 17000760    Free PMC article.
Beta-Catenin stabilizes cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3'-UTR.
Hee Kyu Lee, Sunjoo Jeong.
Nucleic Acids Res, 2006 Oct 17; 34(19). PMID: 17040897    Free PMC article.
Structure and function of latency-associated nuclear antigen.
S C Verma, K Lan, E Robertson.
Curr Top Microbiol Immunol, 2006 Nov 09; 312. PMID: 17089795    Free PMC article.
TCF7L2 and type 2 diabetes--we WNT to know.
U Smith.
Diabetologia, 2006 Nov 15; 50(1). PMID: 17102948
MUC1 oncoprotein functions in activation of fibroblast growth factor receptor signaling.
Jian Ren, Deepak Raina, +3 authors, Donald Kufe.
Mol Cancer Res, 2006 Nov 23; 4(11). PMID: 17114345    Free PMC article.
Characterization of a 60S complex of the adenomatous polyposis coli tumor suppressor protein.
Sreekala Mahadevaiyer, Chong Xu, Barry M Gumbiner.
Biochim Biophys Acta, 2006 Nov 28; 1773(2). PMID: 17126424    Free PMC article.
Dickkopf-1 activates cell death in MDA-MB435 melanoma cells.
Andrei M Mikheev, Svetlana A Mikheeva, Robert Rostomily, Helmut Zarbl.
Biochem Biophys Res Commun, 2006 Dec 05; 352(3). PMID: 17141200    Free PMC article.
Mechanism of adenomatous polyposis coli (APC)-mediated blockage of long-patch base excision repair.
Aruna S Jaiswal, Ramesh Balusu, +2 authors, Satya Narayan.
Biochemistry, 2006 Dec 21; 45(51). PMID: 17176113    Free PMC article.
Wnt and Hedgehog are critical mediators of cigarette smoke-induced lung cancer.
Hassan Lemjabbar-Alaoui, Vijay Dasari, +4 authors, Carol Basbaum.
PLoS One, 2006 Dec 22; 1. PMID: 17183725    Free PMC article.
Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability.
Karin Kroboth, Ian P Newton, +4 authors, Inke S Näthke.
Mol Biol Cell, 2006 Dec 29; 18(3). PMID: 17192415    Free PMC article.
WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells.
Wendy A Woodward, Mercy S Chen, +3 authors, Jeffrey M Rosen.
Proc Natl Acad Sci U S A, 2007 Jan 05; 104(2). PMID: 17202265    Free PMC article.
Highly Cited.
Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis.
Dina Dikovskaya, David Schiffmann, +7 authors, Inke S Näthke.
J Cell Biol, 2007 Jan 18; 176(2). PMID: 17227893    Free PMC article.
Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity.
Dexing Fang, David Hawke, +7 authors, Zhimin Lu.
J Biol Chem, 2007 Feb 09; 282(15). PMID: 17287208    Free PMC article.
Highly Cited.
Aberrant nuclear localization of beta-catenin without genetic alterations in beta-catenin or Axin genes in esophageal cancer.
Junjo Kudo, Tadashi Nishiwaki, +8 authors, Yoshitaka Fujii.
World J Surg Oncol, 2007 Feb 21; 5. PMID: 17309796    Free PMC article.
Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex.
Wen Luo, Annita Peterson, +7 authors, David M Virshup.
EMBO J, 2007 Feb 24; 26(6). PMID: 17318175    Free PMC article.
Raf-1 activation in gastrointestinal carcinoid cells decreases tumor cell adhesion.
David Yü Greenblatt, Muthusamy Kunnimalaiyaan, Herbert Chen.
Am J Surg, 2007 Feb 27; 193(3). PMID: 17320529    Free PMC article.
The molecular culprits underlying precocious mammary gland involution.
Kate D Sutherland, Geoffrey J Lindeman, Jane E Visvader.
J Mammary Gland Biol Neoplasia, 2007 Feb 27; 12(1). PMID: 17323120
Signal transduction induced in endothelial cells by growth factor receptors involved in angiogenesis.
Erhard Hofer, Bernhard Schweighofer.
Thromb Haemost, 2007 Mar 06; 97(3). PMID: 17334501    Free PMC article.
A Wnt-CKIvarepsilon-Rap1 pathway regulates gastrulation by modulating SIPA1L1, a Rap GTPase activating protein.
I-Chun Tsai, Jeffrey D Amack, +3 authors, David M Virshup.
Dev Cell, 2007 Mar 06; 12(3). PMID: 17336901    Free PMC article.
Role of GAC63 in transcriptional activation mediated by beta-catenin.
Yong-Heng Chen, Catherine K Yang, +2 authors, Michael R Stallcup.
Nucleic Acids Res, 2007 Mar 09; 35(6). PMID: 17344318    Free PMC article.
Knocking down Wnt9a mRNA levels increases cellular proliferation.
Yang Xiang, Ge Lin, +2 authors, Guangxiu Lu.
Mol Biol Rep, 2007 Mar 14; 35(2). PMID: 17351820
CBP/p300 are bimodal regulators of Wnt signaling.
Jiong Li, Chris Sutter, +3 authors, Ken M Cadigan.
EMBO J, 2007 Apr 06; 26(9). PMID: 17410209    Free PMC article.
Carrageenan reduces bone morphogenetic protein-4 (BMP4) and activates the Wnt/beta-catenin pathway in normal human colonocytes.
Sumit Bhattacharyya, Alip Borthakur, Pradeep K Dudeja, Joanne K Tobacman.
Dig Dis Sci, 2007 Apr 13; 52(10). PMID: 17429723
Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma.
Kumar Sukhdeo, Mala Mani, +10 authors, Daniel R Carrasco.
Proc Natl Acad Sci U S A, 2007 Apr 25; 104(18). PMID: 17452641    Free PMC article.
All-trans-retinoic acid induces cell growth arrest in a human medulloblastoma cell line.
Qing Chang, Zhengshan Chen, +6 authors, Jiang Gu.
J Neurooncol, 2007 Apr 25; 84(3). PMID: 17453147
Small-molecule synergist of the Wnt/beta-catenin signaling pathway.
Qisheng Zhang, Michael B Major, +9 authors, Sheng Ding.
Proc Natl Acad Sci U S A, 2007 Apr 27; 104(18). PMID: 17460038    Free PMC article.
Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements.
Gun-Hwa Kim, Jin-Kwan Han.
EMBO J, 2007 May 04; 26(10). PMID: 17476309    Free PMC article.
Neuronal apoptosis and reversible motor deficit in dominant-negative GSK-3 conditional transgenic mice.
Raquel Gómez-Sintes, Félix Hernández, +5 authors, José J Lucas.
EMBO J, 2007 May 19; 26(11). PMID: 17510631    Free PMC article.
Association of DNA methylation and epigenetic inactivation of RASSF1A and beta-catenin with metastasis in small bowel carcinoid tumors.
He-Yu Zhang, Kandelaria M Rumilla, +7 authors, Ricardo V Lloyd.
Endocrine, 2007 May 29; 30(3). PMID: 17526942
Calcium signaling in vertebrate embryonic patterning and morphogenesis.
Diane C Slusarski, Francisco Pelegri.
Dev Biol, 2007 May 29; 307(1). PMID: 17531967    Free PMC article.
Inhibition of VEGF-A prevents the angiogenic switch and results in increased survival of Apc+/min mice.
Nina Korsisaari, Ian M Kasman, +6 authors, Napoleone Ferrara.
Proc Natl Acad Sci U S A, 2007 Jun 08; 104(25). PMID: 17553957    Free PMC article.
Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia.
Takao Senda, Akiko Iizuka-Kogo, Takanori Onouchi, Atsushi Shimomura.
Med Mol Morphol, 2007 Jun 19; 40(2). PMID: 17572842
Molecular plasticity of beta-catenin: new insights from single-molecule measurements and MD simulation.
Monica Ritco-Vonsovici, Abdessamad Ababou, Michael Horton.
Protein Sci, 2007 Jul 31; 16(9). PMID: 17660262    Free PMC article.
Zebrafish Naked1 and Naked2 antagonize both canonical and non-canonical Wnt signaling.
Terence J Van Raay, Robert J Coffey, Lilianna Solnica-Krezel.
Dev Biol, 2007 Aug 11; 309(2). PMID: 17689523    Free PMC article.
Analysis of endogenous LRP6 function reveals a novel feedback mechanism by which Wnt negatively regulates its receptor.
Zahid Khan, Sapna Vijayakumar, +2 authors, Anna Bafico.
Mol Cell Biol, 2007 Aug 19; 27(20). PMID: 17698587    Free PMC article.
Parallels between global transcriptional programs of polarizing Caco-2 intestinal epithelial cells in vitro and gene expression programs in normal colon and colon cancer.
Annika M Sääf, Jennifer M Halbleib, +4 authors, Patrick O Brown.
Mol Biol Cell, 2007 Aug 19; 18(11). PMID: 17699589    Free PMC article.
Beta-catenin binds to the downstream region and regulates the expression C-reactive protein gene.
Yong Seok Choi, Jung Hur, Sunjoo Jeong.
Nucleic Acids Res, 2007 Aug 21; 35(16). PMID: 17704137    Free PMC article.
WNT10B functional dualism: beta-catenin/Tcf-dependent growth promotion or independent suppression with deregulated expression in cancer.
Hirohide Yoshikawa, Kenichi Matsubara, +8 authors, Curtis C Harris.
Mol Biol Cell, 2007 Sep 01; 18(11). PMID: 17761539    Free PMC article.
The intrinsically disordered TC-1 interacts with Chibby via regions with high helical propensity.
Chris Gall, Hanyu Xu, +2 authors, Wing Yiu Choy.
Protein Sci, 2007 Oct 02; 16(11). PMID: 17905836    Free PMC article.
Primers on molecular pathways. The glycogen synthase kinase-3beta.
Daniel D Billadeau.
Pancreatology, 2007 Oct 04; 7(5-6). PMID: 17912008    Free PMC article.
Phospho-regulation of Beta-catenin adhesion and signaling functions.
Rebecca Leadem Daugherty, Cara J Gottardi.
Physiology (Bethesda), 2007 Oct 12; 22. PMID: 17928543    Free PMC article.
Highly Cited. Review.
Head and neck cancer: the possible role of stem cells.
C Bianchini, A Ciorba, +2 authors, A Pastore.
Eur Arch Otorhinolaryngol, 2007 Oct 16; 265(1). PMID: 17934745
KIT regulates tyrosine phosphorylation and nuclear localization of beta-catenin in mast cell leukemia.
Tomohiro Kajiguchi, Sunmin Lee, +2 authors, Len Neckers.
Leuk Res, 2007 Oct 24; 32(5). PMID: 17949810    Free PMC article.
Regulatory pathway analysis by high-throughput in situ hybridization.
Axel Visel, James Carson, +6 authors, Gregor Eichele.
PLoS Genet, 2007 Oct 24; 3(10). PMID: 17953485    Free PMC article.
Epstein-Barr virus, beta-catenin, and E-cadherin in gastric carcinomas.
In Mok Jung, Jung Kee Chung, +9 authors, Mee Soo Chang.
J Korean Med Sci, 2007 Nov 06; 22(5). PMID: 17982235    Free PMC article.
Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription.
Amy C Moore, Joseph M Amann, +7 authors, Scott W Hiebert.
Mol Cell Biol, 2007 Nov 28; 28(3). PMID: 18039847    Free PMC article.
Multiple mechanisms are involved in 6-gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells.
Seong-Ho Lee, Maria Cekanova, Seung Joon Baek.
Mol Carcinog, 2007 Dec 07; 47(3). PMID: 18058799    Free PMC article.
Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19Arf/p53 pathway lesions but not p16 Ink4a loss.
Michael T Debies, Shelley A Gestl, +6 authors, Edward J Gunther.
J Clin Invest, 2007 Dec 07; 118(1). PMID: 18060046    Free PMC article.
Frizzled-Dishevelled signaling specificity outcome can be modulated by Diego in Drosophila.
Jun Wu, Andreas Jenny, Ivana Mirkovic, Marek Mlodzik.
Mech Dev, 2007 Dec 11; 125(1-2). PMID: 18065209    Free PMC article.
Multiple PPPS/TP motifs act in a combinatorial fashion to transduce Wnt signaling through LRP6.
Joshua Wolf, Todd R Palmby, +2 authors, J Silvio Gutkind.
FEBS Lett, 2007 Dec 18; 582(2). PMID: 18083125    Free PMC article.
The functions and possible significance of Kremen as the gatekeeper of Wnt signalling in development and pathology.
T Nakamura, T Nakamura, K Matsumoto.
J Cell Mol Med, 2007 Dec 20; 12(2). PMID: 18088386    Free PMC article.
Wingless signaling induces widespread chromatin remodeling of target loci.
David S Parker, Yunyun Y Ni, +2 authors, Ken M Cadigan.
Mol Cell Biol, 2007 Dec 28; 28(5). PMID: 18160704    Free PMC article.
Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo.
Mai Xu, Qing Yu, +3 authors, Jyoti Misra Sen.
Mol Cell Biol, 2007 Dec 28; 28(5). PMID: 18160717    Free PMC article.
ShRNA-mediated gene silencing of beta-catenin inhibits growth of human colon cancer cells.
Wen-Sheng Huang, Jian-Ping Wang, +3 authors, Jin-Ping Ma.
World J Gastroenterol, 2007 Dec 29; 13(48). PMID: 18161931    Free PMC article.
A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells.
Carolina Espina, María Virtudes Céspedes, +8 authors, Juan Carlos Lacal.
Am J Pathol, 2008 Jan 01; 172(1). PMID: 18165265    Free PMC article.
Simulating the G-protein cAMP pathway with a two-compartment reactive lattice gas.
F Castiglione, S Succi.
Theory Biosci, 2008 Jan 19; 123(4). PMID: 18202873
Clinical significance of nuclear non-phosphorylated beta-catenin in acute myeloid leukaemia and myelodysplastic syndrome.
Jinglan Xu, Momoko Suzuki, +9 authors, Tomoki Naoe.
Br J Haematol, 2008 Jan 26; 140(4). PMID: 18217891    Free PMC article.
The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling.
Annouck Luyten, Eva Mortier, +7 authors, Pascale Zimmermann.
Mol Biol Cell, 2008 Feb 08; 19(4). PMID: 18256285    Free PMC article.
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells.
Pantelis Hatzis, Laurens G van der Flier, +12 authors, Hendrik G Stunnenberg.
Mol Cell Biol, 2008 Feb 13; 28(8). PMID: 18268006    Free PMC article.
Highly Cited.
Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains.
Hoanh Tran, Fumihiko Hamada, Thomas Schwarz-Romond, Mariann Bienz.
Genes Dev, 2008 Feb 19; 22(4). PMID: 18281465    Free PMC article.
Correlation between beta-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma.
Madeleine Austinat, Ruediger Dunsch, +3 authors, Frank Gaunitz.
Mol Cancer, 2008 Feb 20; 7. PMID: 18282277    Free PMC article.
Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer.
H Suzuki, M Toyota, +14 authors, T Tokino.
Br J Cancer, 2008 Feb 20; 98(6). PMID: 18283316    Free PMC article.
Highly Cited.
Identification of E2F1 as a positive transcriptional regulator for delta-catenin.
Kwonseop Kim, Minsoo Oh, +5 authors, Qun Lu.
Biochem Biophys Res Commun, 2008 Feb 28; 369(2). PMID: 18302937    Free PMC article.
Oncolytic virotherapy: molecular targets in tumor-selective replication and carrier cell-mediated delivery of oncolytic viruses.
Z Sheng Guo, Stephen H Thorne, David L Bartlett.
Biochim Biophys Acta, 2008 Mar 11; 1785(2). PMID: 18328829    Free PMC article.
Crystal structure of a full-length beta-catenin.
Yi Xing, Ken-Ichi Takemaru, +4 authors, Wenqing Xu.
Structure, 2008 Mar 13; 16(3). PMID: 18334222    Free PMC article.
Wnt/beta-catenin signaling: new (and old) players and new insights.
He Huang, Xi He.
Curr Opin Cell Biol, 2008 Mar 15; 20(2). PMID: 18339531    Free PMC article.
Highly Cited. Review.
Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth.
Ya-Wei Qiang, John D Shaughnessy, Shmuel Yaccoby.
Blood, 2008 Mar 18; 112(2). PMID: 18344425    Free PMC article.
Crosstalk between tumor cells and microenvironment via Wnt pathway in colorectal cancer dissemination.
Dan Huang, Xiang Du.
World J Gastroenterol, 2008 Mar 20; 14(12). PMID: 18350618    Free PMC article.
Micro-proteome analysis using micro-chromatofocusing in intact protein separations.
Hyeyeung Kim, David M Lubman.
J Chromatogr A, 2008 Apr 15; 1194(1). PMID: 18407281    Free PMC article.
Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD).
Mimi Tadjine, Antoine Lampron, +3 authors, Isabelle Bourdeau.
Clin Endocrinol (Oxf), 2008 Apr 19; 69(3). PMID: 18419788    Free PMC article.
Treatment of radioresistant stem-like esophageal cancer cells by an apoptotic gene-armed, telomerase-specific oncolytic adenovirus.
Xiaochun Zhang, Ritsuko Komaki, +2 authors, Joe Y Chang.
Clin Cancer Res, 2008 May 03; 14(9). PMID: 18451249    Free PMC article.
SFRP-4 abrogates Wnt-3a-induced beta-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of in vitro mammary differentiation.
Thecla Constantinou, Fabrizio Baumann, +3 authors, Arun Dharmarajan.
J Mol Signal, 2008 May 03; 3. PMID: 18452624    Free PMC article.
Regulation of epithelial branching morphogenesis and cancer cell growth of the prostate by Wnt signaling.
Bu-Er Wang, Xi-De Wang, +2 authors, Wei-Qiang Gao.
PLoS One, 2008 May 15; 3(5). PMID: 18478098    Free PMC article.
Association of the TCF7L2 polymorphism with colorectal cancer and adenoma risk.
Aditi Hazra, Charles S Fuchs, +2 authors, David J Hunter.
Cancer Causes Control, 2008 May 15; 19(9). PMID: 18478343    Free PMC article.
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex.
Marc Fiedler, María José Sánchez-Barrena, +5 authors, Mariann Bienz.
Mol Cell, 2008 May 24; 30(4). PMID: 18498752    Free PMC article.
Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity.
Veronica R Placencio, Ali-Reza Sharif-Afshar, +7 authors, Neil A Bhowmick.
Cancer Res, 2008 Jun 19; 68(12). PMID: 18559517    Free PMC article.
Axin2 expression identifies progenitor cells in the murine prostate.
Christopher S Ontiveros, Sarah N Salm, E Lynette Wilson.
Prostate, 2008 Jun 20; 68(12). PMID: 18563716    Free PMC article.
Chibby cooperates with 14-3-3 to regulate beta-catenin subcellular distribution and signaling activity.
Feng-Qian Li, Adaobi Mofunanya, Kimberley Harris, Ken-Ichi Takemaru.
J Cell Biol, 2008 Jun 25; 181(7). PMID: 18573912    Free PMC article.
MUC1 oncoprotein promotes growth and survival of human multiple myeloma cells.
Takeshi Kawano, Rehan Ahmad, +3 authors, Donald Kufe.
Int J Oncol, 2008 Jun 26; 33(1). PMID: 18575761    Free PMC article.
G-protein-coupled receptors and melanoma.
Hwa Jin Lee, Brian Wall, Suzie Chen.
Pigment Cell Melanoma Res, 2008 Jun 28; 21(4). PMID: 18582227    Free PMC article.
Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.
Hideyasu Takagi, Shigeru Sasaki, +8 authors, Yasuhisa Shinomura.
J Gastroenterol, 2008 Jul 02; 43(5). PMID: 18592156
Genetic changes of Wnt pathway genes are common events in metaplastic carcinomas of the breast.
Michael J Hayes, Dafydd Thomas, +2 authors, Celina G Kleer.
Clin Cancer Res, 2008 Jul 03; 14(13). PMID: 18593979    Free PMC article.
Wnt signaling: the good and the bad.
Xi Chen, Jun Yang, Paul M Evans, Chunming Liu.
Acta Biochim Biophys Sin (Shanghai), 2008 Jul 08; 40(7). PMID: 18604449    Free PMC article.
Second hit in cervical carcinogenesis process: involvement of wnt/beta catenin pathway.
Carlos Perez-Plasencia, Alfonso Duenas-Gonzalez, Brenda Alatorre-Tavera.
Int Arch Med, 2008 Jul 09; 1(1). PMID: 18606007    Free PMC article.
Intrinsic disorder in scaffold proteins: getting more from less.
Marc S Cortese, Vladimir N Uversky, A Keith Dunker.
Prog Biophys Mol Biol, 2008 Jul 16; 98(1). PMID: 18619997    Free PMC article.
The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells.
Marc de la Roche, Jesper Worm, Mariann Bienz.
BMC Cancer, 2008 Jul 17; 8. PMID: 18627596    Free PMC article.
Silencing mediator for retinoid and thyroid hormone receptor and nuclear receptor corepressor attenuate transcriptional activation by the beta-catenin-TCF4 complex.
Liang-Nian Song, Edward P Gelmann.
J Biol Chem, 2008 Jul 18; 283(38). PMID: 18632669    Free PMC article.
Pathogenesis of malignant pleural mesothelioma and the role of environmental and genetic factors.
Shoshana J Weiner, Siyamek Neragi-Miandoab.
J Carcinog, 2008 Jul 30; 7. PMID: 18662397    Free PMC article.
A novel function of adenomatous polyposis coli (APC) in regulating DNA repair.
Aruna S Jaiswal, Satya Narayan.
Cancer Lett, 2008 Jul 30; 271(2). PMID: 18662849    Free PMC article.
Activation of Wnt signaling in cKit-ITD mediated transformation and imatinib sensitivity in acute myeloid leukemia.
Lara Tickenbrock, Sina Hehn, +6 authors, Hubert Serve.
Int J Hematol, 2008 Aug 01; 88(2). PMID: 18668305
Wnt signaling in angiogenesis.
Nancy L Parmalee, Jan Kitajewski.
Curr Drug Targets, 2008 Aug 05; 9(7). PMID: 18673241    Free PMC article.
Biological background of pediatric medulloblastoma and ependymoma: a review from a translational research perspective.
Judith M de Bont, Roger J Packer, +2 authors, Rob Pieters.
Neuro Oncol, 2008 Aug 05; 10(6). PMID: 18676356    Free PMC article.
Molecular basis of the potential of mesalazine to prevent colorectal cancer.
Carmine Stolfi, Roberto Pellegrini, +2 authors, Giovanni Monteleone.
World J Gastroenterol, 2008 Aug 06; 14(28). PMID: 18680220    Free PMC article.
The WNT signalling pathway and diabetes mellitus.
T Jin.
Diabetologia, 2008 Aug 13; 51(10). PMID: 18696049
Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer.
Xianshu Wang, Ellen L Goode, +8 authors, Fergus J Couch.
Cancer Epidemiol Biomarkers Prev, 2008 Aug 19; 17(8). PMID: 18708403    Free PMC article.
A novel functional screen in human cells identifies MOCA as a negative regulator of Wnt signaling.
Elanite Caspi, Rina Rosin-Arbesfeld.
Mol Biol Cell, 2008 Aug 22; 19(11). PMID: 18716063    Free PMC article.
Increased expression of HSP27 linked to vincristine resistance in human gastric cancer cell line.
Yi-Xuan Yang, Xue-Feng Sun, +8 authors, Zhi-Qiang Xiao.
J Cancer Res Clin Oncol, 2008 Sep 02; 135(2). PMID: 18758817
Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice.
Tamara Grigoryan, Peter Wend, Alexandra Klaus, Walter Birchmeier.
Genes Dev, 2008 Sep 04; 22(17). PMID: 18765787    Free PMC article.
Highly Cited. Review.
Targeting glycogen synthase kinase-3 (GSK-3) in the treatment of Type 2 diabetes.
Katrina MacAulay, James R Woodgett.
Expert Opin Ther Targets, 2008 Sep 11; 12(10). PMID: 18781825    Free PMC article.
Pathogenesis of malignant pleural mesothelioma and the role of environmental and genetic factors.
Shoshana J Weiner, Siyamek Neragi-Miandoab.
J Cancer Res Clin Oncol, 2008 Sep 13; 135(1). PMID: 18787841
Dysregulated molecular networks in head and neck carcinogenesis.
Alfredo A Molinolo, Panomwat Amornphimoltham, +3 authors, J Silvio Gutkind.
Oral Oncol, 2008 Sep 23; 45(4-5). PMID: 18805044    Free PMC article.
Highly Cited. Review.
Tumor hypoxia blocks Wnt processing and secretion through the induction of endoplasmic reticulum stress.
Meletios Verras, Ioanna Papandreou, Ai Lin Lim, Nicholas C Denko.
Mol Cell Biol, 2008 Oct 01; 28(23). PMID: 18824543    Free PMC article.
Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours.
Jürgen Veeck, Nuran Bektas, +4 authors, Edgar Dahl.
Breast Cancer Res, 2008 Oct 02; 10(5). PMID: 18826564    Free PMC article.
A genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression.
Gregory S Yochum, Ryan Cleland, Richard H Goodman.
Mol Cell Biol, 2008 Oct 15; 28(24). PMID: 18852287    Free PMC article.
Overall expression of beta-catenin outperforms its nuclear accumulation in predicting outcomes of colorectal cancers.
Worrawit Wanitsuwan, Samornmas Kanngurn, +2 authors, Surasak Sangkhathat.
World J Gastroenterol, 2008 Oct 22; 14(39). PMID: 18932285    Free PMC article.
Kinetics of Wnt-driven beta-catenin stabilization revealed by quantitative and temporal imaging.
Rami N Hannoush.
PLoS One, 2008 Oct 23; 3(10). PMID: 18941539    Free PMC article.
Simulations of a specific inhibitor of the dishevelled PDZ domain.
Xin Chen, Yuefan Deng.
J Mol Model, 2008 Oct 28; 15(1). PMID: 18953581
Molecular analysis of the beta-catenin gene in patients with the Mayer-Rokitansky-Küster-Hauser syndrome.
Juliana B Drummond, Camila F Rezende, +3 authors, Luiz De Marco.
J Assist Reprod Genet, 2008 Nov 04; 25(11-12). PMID: 18979195    Free PMC article.
Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer.
Jürgen Veeck, Erik Noetzel, +4 authors, Edgar Dahl.
Mol Cancer, 2008 Nov 08; 7. PMID: 18990230    Free PMC article.
Cadherin switching and activation of beta-catenin signaling underlie proinvasive actions of calcitonin-calcitonin receptor axis in prostate cancer.
Girish V Shah, Anbalagan Muralidharan, +2 authors, Shibu Thomas.
J Biol Chem, 2008 Nov 13; 284(2). PMID: 19001380    Free PMC article.
Stem cells: From embryology to cellular therapy? An appraisal of the present state of art.
Sandro Eridani, Vittorio Sgaramella, Lidia Cova.
Cytotechnology, 2008 Nov 13; 44(3). PMID: 19003235    Free PMC article.
Ovarian cancer: emerging concept on cancer stem cells.
Moorthy P Ponnusamy, Surinder K Batra.
J Ovarian Res, 2008 Nov 19; 1(1). PMID: 19014671    Free PMC article.
Crosstalk between the androgen receptor and beta-catenin in castrate-resistant prostate cancer.
Gang Wang, Jun Wang, Marianne D Sadar.
Cancer Res, 2008 Dec 03; 68(23). PMID: 19047173    Free PMC article.
Wnt1 expression induces short-range and long-range cell recruitments that modify mammary tumor development and are not induced by a cell-autonomous beta-catenin effector.
Young Chul Kim, Rod J Clark, Erik A Ranheim, Caroline M Alexander.
Cancer Res, 2008 Dec 17; 68(24). PMID: 19074881    Free PMC article.
Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene.
Benjamin Cieply, Gang Zeng, +2 authors, Satdarshan P S Monga.
Hepatology, 2008 Dec 23; 49(3). PMID: 19101982    Free PMC article.
Gamma-secretase-dependent and -independent effects of presenilin1 on beta-catenin.Tcf-4 transcriptional activity.
Imma Raurell, Montserrat Codina, +4 authors, Mireia Duñach.
PLoS One, 2008 Dec 31; 3(12). PMID: 19114997    Free PMC article.
Intracellular MUC1 peptides inhibit cancer progression.
Benjamin G Bitler, Ina Menzl, +4 authors, Joyce A Schroeder.
Clin Cancer Res, 2009 Jan 02; 15(1). PMID: 19118037    Free PMC article.
Amide derivatives of ethacrynic acid: synthesis and evaluation as antagonists of Wnt/beta-catenin signaling and CLL cell survival.
Guangyi Jin, Desheng Lu, +4 authors, Howard B Cottam.
Bioorg Med Chem Lett, 2009 Jan 06; 19(3). PMID: 19121941    Free PMC article.
Identification of zinc-finger BED domain-containing 3 (Zbed3) as a novel Axin-interacting protein that activates Wnt/beta-catenin signaling.
Ting Chen, Meng Li, +6 authors, Lin Li.
J Biol Chem, 2009 Jan 15; 284(11). PMID: 19141611    Free PMC article.
Wnt/beta-catenin/Tcf signaling pathway activation in malignant progression of rat gliomas induced by transplacental N-ethyl-N-nitrosourea exposure.
Gangadhara Reddy Sareddy, Sundaram Challa, Manas Panigrahi, Phanithi Prakash Babu.
Neurochem Res, 2009 Jan 17; 34(7). PMID: 19148749
Fine-tuning of nuclear-catenin by Chibby and 14-3-3.
Ken-Ichi Takemaru, Victoria Fischer, Feng-Qian Li.
Cell Cycle, 2009 Jan 23; 8(2). PMID: 19158508    Free PMC article.
Wnt genes in the mouse uterus: potential regulation of implantation.
Kanako Hayashi, David W Erikson, +5 authors, Thomas E Spencer.
Biol Reprod, 2009 Jan 24; 80(5). PMID: 19164167    Free PMC article.
Cadherin-bound beta-catenin feeds into the Wnt pathway upon adherens junctions dissociation: evidence for an intersection between beta-catenin pools.
Yoonseok Kam, Vito Quaranta.
PLoS One, 2009 Feb 25; 4(2). PMID: 19238201    Free PMC article.
EWS/ETS regulates the expression of the Dickkopf family in Ewing family tumor cells.
Yoshitaka Miyagawa, Hajime Okita, +6 authors, Nobutaka Kiyokawa.
PLoS One, 2009 Feb 28; 4(2). PMID: 19247449    Free PMC article.
Scaffold Attachment Factor B1 (SAFB1) heterozygosity does not influence Wnt-1 or DMBA-induced tumorigenesis.
Benny Abraham Kaipparettu, Klaudia M Dobrzycka, +6 authors, Steffi Oesterreich.
Mol Cancer, 2009 Mar 10; 8. PMID: 19267898    Free PMC article.
Post-transcriptional regulation of cadherin-11 expression by GSK-3 and beta-catenin in prostate and breast cancer cells.
Anne K Farina, Yong-Sik Bong, Carolyn M Feltes, Stephen W Byers.
PLoS One, 2009 Mar 11; 4(3). PMID: 19274078    Free PMC article.
Wnt/beta-catenin signaling in cerebral cortical development.
Anjen Chenn.
Organogenesis, 2009 Mar 13; 4(2). PMID: 19279718    Free PMC article.
Wnt/beta-catenin signaling in hepatic organogenesis.
Kari Nejak-Bowen, Satdarshan Ps Monga.
Organogenesis, 2009 Mar 13; 4(2). PMID: 19279720    Free PMC article.
Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6.
Geng Wu, He Huang, Jose Garcia Abreu, Xi He.
PLoS One, 2009 Mar 19; 4(3). PMID: 19293931    Free PMC article.
LEF1 in androgen-independent prostate cancer: regulation of androgen receptor expression, prostate cancer growth, and invasion.
Yirong Li, Longgui Wang, +10 authors, Peng Lee.
Cancer Res, 2009 Apr 09; 69(8). PMID: 19351848    Free PMC article.
Endocrine dysfunction in p27Kip1 deficient mice and susceptibility to Wnt-1 driven breast cancer.
Cynthia E Glover, Kay E Gurley, +3 authors, Christopher J Kemp.
Carcinogenesis, 2009 Apr 22; 30(6). PMID: 19380520    Free PMC article.
Constitutive activation of Beta-catenin in uterine stroma and smooth muscle leads to the development of mesenchymal tumors in mice.
Pradeep S Tanwar, Ho-Joon Lee, +4 authors, Jose M Teixeira.
Biol Reprod, 2009 May 01; 81(3). PMID: 19403928    Free PMC article.
Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma.
Mariateresa Fulciniti, Pierfrancesco Tassone, +13 authors, Nikhil C Munshi.
Blood, 2009 May 07; 114(2). PMID: 19417213    Free PMC article.
Highly Cited.
Down-regulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44high/cd24low population which is invasive and resistant to anoikis.
Kelly J Gauger, Jeremy M Hugh, Melissa A Troester, Sallie Smith Schneider.
Cancer Cell Int, 2009 May 09; 9. PMID: 19422694    Free PMC article.
Chibby forms a homodimer through a heptad repeat of leucine residues in its C-terminal coiled-coil motif.
Adaobi Mofunanya, Feng-Qian Li, Jen-Chih Hsieh, Ken-Ichi Takemaru.
BMC Mol Biol, 2009 May 14; 10. PMID: 19435523    Free PMC article.
Utility of DNA postreplication repair protein Rad6B in neoadjuvant chemotherapy response.
Malathy P V Shekhar, Laura A Biernat, +3 authors, Daniel W Visscher.
Med Oncol, 2009 May 26; 27(2). PMID: 19466589
Investigation of BRAF and CTNNB1 activating mutations in adrenocortical tumors.
G Masi, E Lavezzo, +3 authors, L Barzon.
J Endocrinol Invest, 2009 Jun 06; 32(7). PMID: 19498322
Methylation analysis of SFRP genes family in cervical adenocarcinoma.
Ya-Wen Lin, Ming-Tzeung Chung, +4 authors, Mu-Hsien Yu.
J Cancer Res Clin Oncol, 2009 Jun 11; 135(12). PMID: 19513747
Requirement of cell cycle and apoptosis regulator 1 for target gene activation by Wnt and beta-catenin and for anchorage-independent growth of human colon carcinoma cells.
Chen-Yin Ou, Jeong Hoon Kim, Catherine K Yang, Michael R Stallcup.
J Biol Chem, 2009 Jun 13; 284(31). PMID: 19520846    Free PMC article.
RVB1/RVB2: running rings around molecular biology.
Sudhakar Jha, Anindya Dutta.
Mol Cell, 2009 Jun 16; 34(5). PMID: 19524533    Free PMC article.
Phosphoglucose isomerase/autocrine motility factor mediates epithelial and mesenchymal phenotype conversions in breast cancer.
Tatsuyoshi Funasaka, Victor Hogan, Avraham Raz.
Cancer Res, 2009 Jun 18; 69(13). PMID: 19531650    Free PMC article.
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.
Mark M Pomerantz, Nasim Ahmadiyeh, +23 authors, Matthew L Freedman.
Nat Genet, 2009 Jun 30; 41(8). PMID: 19561607    Free PMC article.
Highly Cited.
Wnt signalling and cancer stem cells.
Jesús Espada, Moisés B Calvo, Silvia Díaz-Prado, Vanessa Medina.
Clin Transl Oncol, 2009 Jul 04; 11(7). PMID: 19574199
ErbB4 splice variants Cyt1 and Cyt2 differ by 16 amino acids and exert opposing effects on the mammary epithelium in vivo.
Rebecca S Muraoka-Cook, Melissa A Sandahl, +6 authors, H Shelton Earp.
Mol Cell Biol, 2009 Jul 15; 29(18). PMID: 19596786    Free PMC article.
Activity of the beta-catenin phosphodestruction complex at cell-cell contacts is enhanced by cadherin-based adhesion.
Meghan T Maher, Annette S Flozak, +2 authors, Cara J Gottardi.
J Cell Biol, 2009 Jul 22; 186(2). PMID: 19620634    Free PMC article.
Hypothesis: neoplasms in myotonic dystrophy.
Christine M Mueller, James E Hilbert, +3 authors, Mark H Greene.
Cancer Causes Control, 2009 Jul 31; 20(10). PMID: 19642006    Free PMC article.
Is there more to Wnt signalling in breast cancer than stabilisation of beta-catenin?
Giovanna M Collu, Olivier Meurette, Keith Brennan.
Breast Cancer Res, 2009 Aug 12; 11(4). PMID: 19664193    Free PMC article.
Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/beta-catenin signaling pathway.
Okay Saydam, Yiping Shen, +11 authors, Xandra O Breakefield.
Mol Cell Biol, 2009 Aug 26; 29(21). PMID: 19703993    Free PMC article.
Highly Cited.
Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling.
Amanda Mikels, Yasuhiro Minami, Roel Nusse.
J Biol Chem, 2009 Sep 02; 284(44). PMID: 19720827    Free PMC article.
HMGA1 is induced by Wnt/beta-catenin pathway and maintains cell proliferation in gastric cancer.
Shin-ichi Akaboshi, Sugiko Watanabe, +8 authors, Mitsuyoshi Nakao.
Am J Pathol, 2009 Sep 05; 175(4). PMID: 19729480    Free PMC article.
Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/β-catenin antagonists against human osteosarcoma cells.
Pay-Chin Leow, Quan Tian, +2 authors, Pui-Lai Rachel Ee.
Invest New Drugs, 2009 Sep 05; 28(6). PMID: 19730790
Networking of differentially expressed genes in human cancer cells resistant to methotrexate.
Elisabet Selga, Carlota Oleaga, +3 authors, Carlos J Ciudad.
Genome Med, 2009 Sep 08; 1(9). PMID: 19732436    Free PMC article.
BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells.
Mala Mani, Daniel E Carrasco, +11 authors, Daniel R Carrasco.
Cancer Res, 2009 Sep 10; 69(19). PMID: 19738061    Free PMC article.
Role of Wnt/β-catenin signaling in liver metabolism and cancer.
Satdarshan Pal Singh Monga.
Int J Biochem Cell Biol, 2009 Sep 15; 43(7). PMID: 19747566    Free PMC article.
Molecular clustering of endometrial carcinoma based on estrogen-induced gene expression.
Shannon N Westin, Russell R Broaddus, +8 authors, David S Loose.
Cancer Biol Ther, 2009 Sep 17; 8(22). PMID: 19755863    Free PMC article.
Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells.
Wei Wei, Mei-Sze Chua, Susan Grepper, Samuel K So.
Mol Cancer, 2009 Sep 26; 8. PMID: 19778454    Free PMC article.
Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1.
Astrid Rohrbeck, Jürgen Borlak.
PLoS One, 2009 Oct 09; 4(10). PMID: 19812696    Free PMC article.
Main roads to melanoma.
Giuseppe Palmieri, Mariaelena Capone, +7 authors, Paolo A Ascierto.
J Transl Med, 2009 Oct 16; 7. PMID: 19828018    Free PMC article.
Mesalamine inhibits epithelial beta-catenin activation in chronic ulcerative colitis.
Jeffrey B Brown, Goo Lee, +9 authors, Terrence A Barrett.
Gastroenterology, 2009 Nov 03; 138(2). PMID: 19879273    Free PMC article.
Regulation of CLU gene expression by oncogenes and epigenetic factors implications for tumorigenesis.
Arturo Sala, Saverio Bettuzzi, +3 authors, Andrei Thomas-Tikhonenko.
Adv Cancer Res, 2009 Nov 03; 105. PMID: 19879426    Free PMC article.
beta-Arrestins - scaffolds and signalling elements essential for WNT/Frizzled signalling pathways?
Gunnar Schulte, Alexandra Schambony, Vítezslav Bryja.
Br J Pharmacol, 2009 Nov 06; 159(5). PMID: 19888962    Free PMC article.
Gene expression profiling in mouse liver infected with Clonorchis sinensis metacercariae.
Dong Min Kim, Byung-Sam Ko, +6 authors, Il-Chul Kim.
Parasitol Res, 2009 Nov 11; 106(1). PMID: 19902254
Control of TCF-4 expression by VDR and vitamin D in the mouse mammary gland and colorectal cancer cell lines.
Marcy E Beildeck, Md Islam, +2 authors, Stephen W Byers.
PLoS One, 2009 Nov 20; 4(11). PMID: 19924301    Free PMC article.
Beta-catenin/T-cell factor signaling is activated during lung injury and promotes the survival and migration of alveolar epithelial cells.
Annette S Flozak, Anna P Lam, +7 authors, Cara J Gottardi.
J Biol Chem, 2009 Nov 26; 285(5). PMID: 19933277    Free PMC article.
Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.
Feng-Qian Li, Adaobi Mofunanya, +2 authors, Ken-Ichi Takemaru.
Mol Biol Cell, 2009 Nov 27; 21(2). PMID: 19940019    Free PMC article.
EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin.
Haitao Ji, Ji Wang, +9 authors, Zhimin Lu.
Mol Cell, 2009 Nov 28; 36(4). PMID: 19941816    Free PMC article.
Highly Cited.
Destruction of a destructor: a new avenue for cancer therapeutics targeting the Wnt pathway.
Chunming Liu, Xi He.
J Mol Cell Biol, 2009 Dec 17; 2(2). PMID: 20008332    Free PMC article.
Ethacrynic acid exhibits selective toxicity to chronic lymphocytic leukemia cells by inhibition of the Wnt/beta-catenin pathway.
Desheng Lu, Jerry X Liu, +6 authors, Dennis A Carson.
PLoS One, 2009 Dec 17; 4(12). PMID: 20011538    Free PMC article.
Differences in protein expression and gene amplification of cyclins between colon and rectal adenocarcinomas.
Rolf Aamodt, Kristin Jonsdottir, +3 authors, Ida R K Bukholm.
Gastroenterol Res Pract, 2009 Dec 24; 2009. PMID: 20029639    Free PMC article.
Reconstitution of secreted frizzled-related protein 1 suppresses tumor growth and lung metastasis in an orthotopic model of hepatocellular carcinoma.
Gui-Xing Jiang, Wei Liu, +6 authors, Shi-Yong Zhao.
Dig Dis Sci, 2009 Dec 25; 55(10). PMID: 20033841
FRAT1 expression and its correlation with pathologic grade, proliferation, and apoptosis in human astrocytomas.
Geng Guo, Bolin Liu, +8 authors, Xiaoyan Chen.
Med Oncol, 2009 Dec 31; 28(1). PMID: 20041315
Involvement of Wnt signaling in dermal fibroblasts.
Kenji Kabashima, Jun-Ichi Sakabe, +3 authors, Yoshiki Tokura.
Am J Pathol, 2010 Jan 01; 176(2). PMID: 20042673    Free PMC article.
Involvement of the residues of GSKIP, AxinGID, and FRATtide in their binding with GSK3beta to unravel a novel C-terminal scaffold-binding region.
Shen-Long Howng, Chi-Ching Hwang, +11 authors, Yi-Ren Hong.
Mol Cell Biochem, 2010 Jan 01; 339(1-2). PMID: 20043192
Fate specification and tissue-specific cell cycle control of the Caenorhabditis elegans intestine.
Alexandra Segref, Juan Cabello, +2 authors, Iain L Johnstone.
Mol Biol Cell, 2010 Jan 08; 21(5). PMID: 20053685    Free PMC article.
Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.
Fergus J Couch, Xianshu Wang, +3 authors, Robert R McWilliams.
Cancer Epidemiol Biomarkers Prev, 2010 Jan 09; 19(1). PMID: 20056645    Free PMC article.
TCF1 and beta-catenin regulate T cell development and function.
Qing Yu, Archna Sharma, Jyoti Misra Sen.
Immunol Res, 2010 Jan 19; 47(1-3). PMID: 20082155    Free PMC article.
Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo.
Michael Buchert, Dimitris Athineos, +16 authors, Matthias Ernst.
PLoS Genet, 2010 Jan 20; 6(1). PMID: 20084116    Free PMC article.
3'-end sequencing for expression quantification (3SEQ) from archival tumor samples.
Andrew H Beck, Ziming Weng, +8 authors, Robert B West.
PLoS One, 2010 Jan 26; 5(1). PMID: 20098735    Free PMC article.
Molecular analysis of mutations for the adenomatous polyposis coli (APC) gene in Romanian patients with colorectal cancer.
M Toma, D Cimponeriu, +4 authors, L Gavrilă.
J Med Life, 2008 Oct 01; 1(4). PMID: 20108522    Free PMC article.
Wnt gene expression in human trabecular meshwork cells.
Rajalekshmy Shyam, Xiang Shen, Beatrice Y J T Yue, Kelly K Wentz-Hunter.
Mol Vis, 2010 Jan 30; 16. PMID: 20111673    Free PMC article.
Helicobacter pylori-induced activation of beta-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled.
Thorsten Gnad, Maria Feoktistova, +2 authors, Michael Naumann.
Mol Cancer, 2010 Feb 09; 9. PMID: 20137080    Free PMC article.
Adenoviral vector-based strategies for cancer therapy.
Anurag Sharma, Manish Tandon, Dinesh S Bangari, Suresh K Mittal.
Curr Drug ther, 2010 Feb 18; 4(2). PMID: 20160875    Free PMC article.
Dehydroepiandrosterone administration or G{alpha}q overexpression induces {beta}-catenin/T-Cell factor signaling and growth via increasing association of estrogen receptor-{beta}/Dishevelled2 in androgen-independent prostate cancer cells.
Xunxian Liu, Julia T Arnold, Marc R Blackman.
Endocrinology, 2010 Feb 24; 151(4). PMID: 20176724    Free PMC article.
Myristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membrane.
Tianhui Hu, Cunxi Li, +5 authors, Robert J Coffey.
J Biol Chem, 2010 Feb 24; 285(18). PMID: 20177058    Free PMC article.
Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling.
Julian Heuberger, Walter Birchmeier.
Cold Spring Harb Perspect Biol, 2010 Feb 26; 2(2). PMID: 20182623    Free PMC article.
Highly Cited. Review.
Reduced beta-catenin expression is associated with good prognosis in Astrocytoma.
Li-Ying Zhang, Li-Na Jiang, +7 authors, Qing Li.
Pathol Oncol Res, 2010 Feb 26; 16(2). PMID: 20182836
Wnt inhibitory factor 1 decreases tumorigenesis and metastasis in osteosarcoma.
Elyssa M Rubin, Yi Guo, +3 authors, Bang H Hoang.
Mol Cancer Ther, 2010 Mar 04; 9(3). PMID: 20197388    Free PMC article.
2-methoxyestradiol inhibits Barrett's esophageal adenocarcinoma growth and differentiation through differential regulation of the beta-catenin-E-cadherin axis.
Suman Kambhampati, Snigdha Banerjee, +7 authors, Sushanta K Banerjee.
Mol Cancer Ther, 2010 Mar 04; 9(3). PMID: 20197389    Free PMC article.
Decreased pygopus 2 expression suppresses glioblastoma U251 cell growth.
Zhan-Xiang Wang, Yu-Ying Chen, +5 authors, Hai-Dong Wang.
J Neurooncol, 2010 Mar 06; 100(1). PMID: 20204459
Striking the target in Wnt-y conditions: intervening in Wnt signaling during cancer progression.
Tura C Camilli, Ashani T Weeraratna.
Biochem Pharmacol, 2010 Mar 10; 80(5). PMID: 20211149    Free PMC article.
Protease-activated receptor-1 (PAR1) acts via a novel Galpha13-dishevelled axis to stabilize beta-catenin levels.
Hagit Turm, Myriam Maoz, +3 authors, Rachel Bar-Shavit.
J Biol Chem, 2010 Mar 13; 285(20). PMID: 20223821    Free PMC article.
Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells.
Shinji Matsumoto, Katsumi Fumoto, +2 authors, Akira Kikuchi.
EMBO J, 2010 Mar 13; 29(7). PMID: 20224554    Free PMC article.
Development of a bioassay for detection of Wnt-binding affinities for individual frizzled receptors.
Kendra S Carmon, David S Loose.
Anal Biochem, 2010 Mar 17; 401(2). PMID: 20227380    Free PMC article.
β-Catenin overexpression in malignant glioma and its role in proliferation and apoptosis in glioblastma cells.
Xiangrong Liu, Lei Wang, +3 authors, Feng Ling.
Med Oncol, 2010 Mar 20; 28(2). PMID: 20300972
Repression of beta-catenin signaling by PPAR gamma ligands.
Desheng Lu, Dennis A Carson.
Eur J Pharmacol, 2010 Mar 23; 636(1-3). PMID: 20303941    Free PMC article.
Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea.
Yujin Zhang, Mindy K Call, +8 authors, Chia-Yang Liu.
J Cell Sci, 2010 Mar 25; 123(Pt 8). PMID: 20332116    Free PMC article.
The role of Pygopus 2 in rat glioma cell growth.
Yu-Ying Chen, Bo-An Li, +6 authors, Zhan-Xiang Wang.
Med Oncol, 2010 Apr 03; 28(2). PMID: 20361361
Pro-oncogenic and anti-oncogenic pathways: opportunities and challenges of cancer therapy.
Jiao Zhang, Yan-Hua Chen, Qun Lu.
Future Oncol, 2010 Apr 09; 6(4). PMID: 20373871    Free PMC article.
Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin.
Kari N Nejak-Bowen, Michael D Thompson, +5 authors, Satdarshan P S Monga.
Hepatology, 2010 May 01; 51(5). PMID: 20432254    Free PMC article.
Mechanism of inhibition of MMTV-neu and MMTV-wnt1 induced mammary oncogenesis by RARalpha agonist AM580.
Y Lu, S Bertran, +2 authors, E F Farias.
Oncogene, 2010 May 11; 29(25). PMID: 20453882    Free PMC article.
Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq.
Daniel Bottomly, Sydney L Kyler, Shannon K McWeeney, Gregory S Yochum.
Nucleic Acids Res, 2010 May 13; 38(17). PMID: 20460455    Free PMC article.
EGFR(s) in aging and carcinogenesis of the gastrointestinal tract.
Jyoti Nautiyal, Shailender Singh Kanwar, Adhip P N Majumdar.
Curr Protein Pept Sci, 2010 May 25; 11(6). PMID: 20491625    Free PMC article.
Genome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method.
Christian Hödar, Rodrigo Assar, +6 authors, Alejandro Maass.
BMC Genomics, 2010 Jun 03; 11. PMID: 20515496    Free PMC article.
Cytokinesis proteins Tum and Pav have a nuclear role in Wnt regulation.
Whitney M Jones, Anna T Chao, +2 authors, Amy Bejsovec.
J Cell Sci, 2010 Jun 03; 123(Pt 13). PMID: 20516152    Free PMC article.
Comparative proteomic analysis of low stage and high stage endometrioid ovarian adenocarcinomas.
Hyeyeung Kim, Rong Wu, +7 authors, David M Lubman.
Proteomics Clin Appl, 2008 Mar 07; 2(4). PMID: 20523764    Free PMC article.
Targeting the perpetrator: breast cancer stem cell therapeutics.
Arindam Pal, Kelli E Valdez, Martha Z Carletti, Fariba Behbod.
Curr Drug Targets, 2010 Jun 16; 11(9). PMID: 20545606    Free PMC article.
Genome-wide analysis of CDX2 binding in intestinal epithelial cells (Caco-2).
Mette Boyd, Morten Hansen, +7 authors, Jesper T Troelsen.
J Biol Chem, 2010 Jun 17; 285(33). PMID: 20551321    Free PMC article.
Molecular imaging of glycogen synthase kinase-3beta and casein kinase-1alpha kinases.
Shyam Nyati, Rajesh Ranga, +2 authors, Mahaveer Swaroop Bhojani.
Anal Biochem, 2010 Jun 22; 405(2). PMID: 20561505    Free PMC article.
Quantification of beta-catenin signaling components in colon cancer cell lines, tissue sections, and microdissected tumor cells using reaction monitoring mass spectrometry.
Yi Chen, Mike Gruidl, +9 authors, John M Koomen.
J Proteome Res, 2010 Jul 02; 9(8). PMID: 20590165    Free PMC article.
E-cadherin promoter hypermethylation may contribute to protein inactivation in pterygia.
Chi-Hsien Young, Yu-Te Chiu, +5 authors, Yi-Yu Tsai.
Mol Vis, 2010 Jul 03; 16. PMID: 20596253    Free PMC article.
Delta-catenin/NPRAP: A new member of the glycogen synthase kinase-3beta signaling complex that promotes beta-catenin turnover in neurons.
Sonja Bareiss, Kwonseop Kim, Qun Lu.
J Neurosci Res, 2010 Jul 14; 88(11). PMID: 20623542    Free PMC article.
Uncovering packaging features of co-regulated modules based on human protein interaction and transcriptional regulatory networks.
Lina Chen, Hong Wang, +8 authors, Xia Li.
BMC Bioinformatics, 2010 Jul 24; 11. PMID: 20649980    Free PMC article.
Cigarette smoke induces promoter methylation of single-stranded DNA-binding protein 2 in human esophageal squamous cell carcinoma.
Yiping Huang, Xiaofei Chang, +8 authors, Myoung Sook Kim.
Int J Cancer, 2010 Jul 27; 128(10). PMID: 20658532    Free PMC article.
Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer.
Ciara Metcalfe, Ashraf E K Ibrahim, +6 authors, Mariann Bienz.
Cancer Res, 2010 Jul 29; 70(16). PMID: 20663899    Free PMC article.
Stat3 activates the receptor tyrosine kinase like orphan receptor-1 gene in chronic lymphocytic leukemia cells.
Ping Li, David Harris, +3 authors, Zeev Estrov.
PLoS One, 2010 Aug 06; 5(7). PMID: 20686606    Free PMC article.
Mutations in the WTX-gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers.
Silvio K Scheel, Marc Porzner, +3 authors, Andreas Jung.
BMC Cancer, 2010 Aug 11; 10. PMID: 20696052    Free PMC article.
Wnt signalling in implantation, decidualisation and placental differentiation--review.
S Sonderegger, J Pollheimer, M Knöfler.
Placenta, 2010 Aug 19; 31(10). PMID: 20716463    Free PMC article.
Analysis of β-catenin alterations in colon tumors: a novel exon 3 mutation.
Elif Akisik, Dursun Buğra, Sumer Yamaner, Nejat Dalay.
Tumour Biol, 2010 Aug 19; 32(1). PMID: 20717765
γ-Catenin is an independent prognostic marker in early stage colorectal cancer.
Jutta Maria Nagel, Lydia Kriegl, +6 authors, Frank Thomas Kolligs.
Int J Colorectal Dis, 2010 Aug 26; 25(11). PMID: 20737155
Wnt/beta-Catenin pathway in human glioma: expression pattern and clinical/prognostic correlations.
Ce Liu, Yanyang Tu, +9 authors, Lianshu Ding.
Clin Exp Med, 2010 Sep 03; 11(2). PMID: 20809334
The Prognostic Impact of Protein Expression of E-Cadherin-Catenin Complexes Differs between Rectal and Colon Carcinoma.
Rolf Aamodt, Johan Bondi, +3 authors, Ida R K Bukholm.
Gastroenterol Res Pract, 2010 Sep 04; 2010. PMID: 20814557    Free PMC article.
β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation.
I Ahmad, J P Morton, +9 authors, O J Sansom.
Oncogene, 2010 Sep 08; 30(2). PMID: 20818428    Free PMC article.
STAT3 upregulates the protein expression and transcriptional activity of β-catenin in breast cancer.
Hanan Armanious, Pascal Gelebart, +2 authors, Raymond Lai.
Int J Clin Exp Pathol, 2010 Sep 11; 3(7). PMID: 20830236    Free PMC article.
Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling.
Arthit Chairoungdua, Danielle L Smith, +2 authors, Michael J Caplan.
J Cell Biol, 2010 Sep 15; 190(6). PMID: 20837771    Free PMC article.
Highly Cited.
Amyloid-β production via cleavage of amyloid-β protein precursor is modulated by cell density.
Can Zhang, Andrew Browne, +5 authors, Rudolph E Tanzi.
J Alzheimers Dis, 2010 Sep 18; 22(2). PMID: 20847415    Free PMC article.
Wnt signaling controls the stem cell-like asymmetric division of the epithelial seam cells during C. elegans larval development.
Julie E Gleason, David M Eisenmann.
Dev Biol, 2010 Sep 21; 348(1). PMID: 20849842    Free PMC article.
Candidate genes and potential targets for therapeutics in Wilms' tumour.
Christopher Blackmore, Max J Coppes, Aru Narendran.
Clin Transl Oncol, 2010 Sep 21; 12(9). PMID: 20851800
Integrative genome-wide approaches in embryonic stem cell research.
Xinyue Zhang, Jing Huang.
Integr Biol (Camb), 2010 Sep 21; 2(10). PMID: 20852801    Free PMC article.
α-Catenin inhibits glioma cell migration, invasion, and proliferation by suppression of β-catenin transactivation.
Haitao Ji, Ji Wang, +2 authors, Zhimin Lu.
J Neurooncol, 2010 Sep 28; 103(3). PMID: 20872274
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α.
Curtis A Thorne, Alison J Hanson, +16 authors, Ethan Lee.
Nat Chem Biol, 2010 Oct 05; 6(11). PMID: 20890287    Free PMC article.
Highly Cited.
Effect of the modulation of leucine zipper tumor suppressor 2 expression on proliferation of various cancer cells functions as a tumor suppressor.
Jong Myung Kim, Ji Sun Song, +4 authors, Jin Sup Jung.
Mol Cell Biochem, 2010 Oct 05; 346(1-2). PMID: 20890637
Pygo2 associates with MLL2 histone methyltransferase and GCN5 histone acetyltransferase complexes to augment Wnt target gene expression and breast cancer stem-like cell expansion.
Jiakun Chen, Qicong Luo, +10 authors, Boan Li.
Mol Cell Biol, 2010 Oct 13; 30(24). PMID: 20937768    Free PMC article.
Dickkopf-1 (DKK-1) stimulated prostate cancer growth and metastasis and inhibited bone formation in osteoblastic bone metastases.
Nanda K Thudi, Chelsea K Martin, +7 authors, Thomas J Rosol.
Prostate, 2010 Oct 20; 71(6). PMID: 20957670    Free PMC article.
WNTs in the neonatal mouse uterus: potential regulation of endometrial gland development.
Kanako Hayashi, Shin Yoshioka, +5 authors, James A MacLean.
Biol Reprod, 2010 Oct 22; 84(2). PMID: 20962251    Free PMC article.
Up-regulated expression of type II very low density lipoprotein receptor correlates with cancer metastasis and has a potential link to β-catenin in different cancers.
Lei He, Yanjun Lu, +3 authors, Shen Qu.
BMC Cancer, 2010 Nov 05; 10. PMID: 21047397    Free PMC article.
AXIN2 polymorphism and its association with prostate cancer in a Turkish population.
Ergun Pinarbasi, Emine Gulsen Gunes, +2 authors, Yavuz Silig.
Med Oncol, 2010 Nov 12; 28(4). PMID: 21069480
How does cAMP/protein kinase A signaling lead to tumors in the adrenal cortex and other tissues?
Madson Q Almeida, Constantine A Stratakis.
Mol Cell Endocrinol, 2010 Nov 30; 336(1-2). PMID: 21111774    Free PMC article.
The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin.
Avital Hay-Koren, Michal Caspi, Alona Zilberberg, Rina Rosin-Arbesfeld.
Mol Biol Cell, 2010 Dec 02; 22(3). PMID: 21118991    Free PMC article.
Galectin-1 is silenced by promoter hypermethylation and its re-expression induces apoptosis in human colorectal cancer cells.
Arun Satelli, U Subrahmanyeswara Rao.
Cancer Lett, 2010 Dec 03; 301(1). PMID: 21122983    Free PMC article.
Wnt/β-catenin activation promotes prostate tumor progression in a mouse model.
X Yu, Y Wang, +2 authors, R J Matusik.
Oncogene, 2010 Dec 15; 30(16). PMID: 21151173    Free PMC article.
Independent interactions of phosphorylated β-catenin with E-cadherin at cell-cell contacts and APC at cell protrusions.
Maree C Faux, Janine L Coates, +2 authors, Antony W Burgess.
PLoS One, 2010 Dec 15; 5(11). PMID: 21152425    Free PMC article.
CyclinD1 protein expressed in pterygia is associated with β-catenin protein localization.
Jai-Nien Tung, Chun-Chi Chiang, +4 authors, Ya-Wen Cheng.
Mol Vis, 2010 Dec 24; 16. PMID: 21179427    Free PMC article.
Structural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathway.
Sulayman Mokhtarzada, Corey Yu, Anne Brickenden, Wing-Yiu Choy.
Biochemistry, 2010 Dec 25; 50(5). PMID: 21182262    Free PMC article.
Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad.
Kari Nichole Nejak-Bowen, Satdarshan P S Monga.
Semin Cancer Biol, 2010 Dec 25; 21(1). PMID: 21182948    Free PMC article.
Highly Cited. Review.
Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the expression of β-catenin, leading to a rapid proliferation of pancreatic cells.
Il-Rae Cho, Sang Seok Koh, +8 authors, Young-Hwa Chung.
Exp Mol Med, 2011 Jan 05; 43(2). PMID: 21196815    Free PMC article.
DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism.
Sripathi M Sureban, Randal May, +10 authors, Courtney W Houchen.
Cancer Res, 2011 Feb 03; 71(6). PMID: 21285251    Free PMC article.
Highly Cited.
Fluorinated N,N-dialkylaminostilbenes for Wnt pathway inhibition and colon cancer repression.
Wen Zhang, Vitaliy Sviripa, +7 authors, Chunming Liu.
J Med Chem, 2011 Feb 05; 54(5). PMID: 21291235    Free PMC article.
Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds.
Yanyan Li, Max S Wicha, Steven J Schwartz, Duxin Sun.
J Nutr Biochem, 2011 Feb 08; 22(9). PMID: 21295962    Free PMC article.
Loss of a single Hic1 allele accelerates polyp formation in Apc(Δ716) mice.
H P Mohammad, W Zhang, +8 authors, S B Baylin.
Oncogene, 2011 Feb 08; 30(23). PMID: 21297660    Free PMC article.
Characterization of β-catenin expression in canine osteosarcoma.
T J Stein, K E Holmes, +2 authors, M K Huelsmeyer.
Vet Comp Oncol, 2011 Feb 10; 9(1). PMID: 21303455    Free PMC article.
SFRP1 reduction results in an increased sensitivity to TGF-β signaling.
Kelly J Gauger, Kerry L Chenausky, Molly E Murray, Sallie S Schneider.
BMC Cancer, 2011 Feb 10; 11. PMID: 21303533    Free PMC article.
Expression of osteopontin coregulators in primary colorectal cancer and associated liver metastases.
D J Mole, C O'Neill, +6 authors, F C Campbell.
Br J Cancer, 2011 Feb 24; 104(6). PMID: 21343932    Free PMC article.
Snapshots of protein dynamics and post-translational modifications in one experiment--beta-catenin and its functions.
Katrin Luckert, Frank Götschel, +3 authors, Oliver Pötz.
Mol Cell Proteomics, 2011 Mar 08; 10(5). PMID: 21378377    Free PMC article.
An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway.
Foster C Gonsalves, Keren Klein, +7 authors, Ramanuj DasGupta.
Proc Natl Acad Sci U S A, 2011 Mar 12; 108(15). PMID: 21393571    Free PMC article.
Highly Cited.
Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers.
Miyako Yamamoto, Emili Cid, Samuel Bru, Fumiichiro Yamamoto.
PLoS One, 2011 Mar 23; 6(3). PMID: 21423795    Free PMC article.
Mutant K-Ras increases GSK-3β gene expression via an ETS-p300 transcriptional complex in pancreatic cancer.
J-S Zhang, A Koenig, +4 authors, D D Billadeau.
Oncogene, 2011 Mar 29; 30(34). PMID: 21441955    Free PMC article.
Regulation of β-catenin by t-DARPP in upper gastrointestinal cancer cells.
Bhavatarini Vangamudi, Shoumin Zhu, +2 authors, Wael El-Rifai.
Mol Cancer, 2011 Mar 31; 10. PMID: 21447180    Free PMC article.
Zipper-interacting protein kinase (ZIPK) modulates canonical Wnt/beta-catenin signaling through interaction with Nemo-like kinase and T-cell factor 4 (NLK/TCF4).
Sumihito Togi, Osamu Ikeda, +8 authors, Tadashi Matsuda.
J Biol Chem, 2011 Apr 02; 286(21). PMID: 21454679    Free PMC article.
Tumor suppressor gene adenomatous polyposis coli downregulates intestinal transport.
Rexhep Rexhepaj, Anand Rotte, +9 authors, Florian Lang.
Pflugers Arch, 2011 Apr 09; 461(5). PMID: 21476133
A coactivator role of CARM1 in the dysregulation of β-catenin activity in colorectal cancer cell growth and gene expression.
Chen-Yin Ou, Melissa J LaBonte, +8 authors, Michael R Stallcup.
Mol Cancer Res, 2011 Apr 12; 9(5). PMID: 21478268    Free PMC article.
Wnt signaling and colon carcinogenesis: beyond APC.
Rani Najdi, Randall F Holcombe, Marian L Waterman.
J Carcinog, 2011 Apr 13; 10. PMID: 21483657    Free PMC article.
Highly Cited.
Methyl jasmonate down-regulates survivin expression and sensitizes colon carcinoma cells towards TRAIL-induced cytotoxicity.
Z Raviv, A Zilberberg, +5 authors, E Flescher.
Br J Pharmacol, 2011 Apr 14; 164(5). PMID: 21486277    Free PMC article.
A genome-wide siRNA screen identifies novel phospho-enzymes affecting Wnt/β-catenin signaling in mouse embryonic stem cells.
Jody Groenendyk, Marek Michalak.
Stem Cell Rev Rep, 2011 Apr 16; 7(4). PMID: 21494821
Postnatal deletion of Wnt7a inhibits uterine gland morphogenesis and compromises adult fertility in mice.
Kathrin A Dunlap, Justyna Filant, +8 authors, Thomas E Spencer.
Biol Reprod, 2011 Apr 22; 85(2). PMID: 21508348    Free PMC article.
Potential relation of aberrant proteolysis of human protein tyrosine kinase 7 (PTK7) chuzhoi by membrane type 1 matrix metalloproteinase (MT1-MMP) to congenital defects.
Vladislav S Golubkov, Alexander E Aleshin, Alex Y Strongin.
J Biol Chem, 2011 Apr 27; 286(23). PMID: 21518755    Free PMC article.
Multiple Wnt/ß-catenin responsive enhancers align with the MYC promoter through long-range chromatin loops.
Gregory S Yochum.
PLoS One, 2011 May 03; 6(4). PMID: 21533051    Free PMC article.
En1 and Wnt signaling in midbrain dopaminergic neuronal development.
Maria T M Alves dos Santos, Marten P Smidt.
Neural Dev, 2011 May 17; 6. PMID: 21569278    Free PMC article.
High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene, CDC25A.
Sapna Vijayakumar, Guizhong Liu, +5 authors, Stuart A Aaronson.
Cancer Cell, 2011 May 18; 19(5). PMID: 21575861    Free PMC article.
Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans.
Carles Gaston-Massuet, Cynthia Lilian Andoniadou, +9 authors, Juan Pedro Martinez-Barbera.
Proc Natl Acad Sci U S A, 2011 Jun 04; 108(28). PMID: 21636786    Free PMC article.
Arginine methylation of G3BP1 in response to Wnt3a regulates β-catenin mRNA.
Rama Kamesh Bikkavilli, Craig C Malbon.
J Cell Sci, 2011 Jun 10; 124(Pt 13). PMID: 21652632    Free PMC article.
Influence of β-catenin small interfering RNA on human osteosarcoma cells.
Fan Zhang, Anmin Chen, +2 authors, Fengjing Guo.
J Huazhong Univ Sci Technolog Med Sci, 2011 Jun 15; 31(3). PMID: 21671177
E-cadherin and β-catenin expression in sebaceous eyelid adenocarcinomas.
Liang Li, Zhe Zhang, +3 authors, Jost B Jonas.
Graefes Arch Clin Exp Ophthalmol, 2011 Jul 09; 249(12). PMID: 21739269
Rad6B acts downstream of Wnt signaling to stabilize β-catenin: Implications for a novel Wnt/β-catenin target.
Brigitte Gerard, Larry Tait, Pratima Nangia-Makker, Malathy Pv Shekhar.
J Mol Signal, 2011 Jul 20; 6. PMID: 21767405    Free PMC article.
Clinicopathological significance of E-cadherin, β-catenin and p53 expression in gastric adenocarinoma.
Mohammad Reza Zali, Omeed Moaven, +5 authors, Mohammad Reza Abbaszadegan.
J Res Med Sci, 2009 Jul 01; 14(4). PMID: 21772890    Free PMC article.
Chromosome 8q24-Associated Cancers and MYC.
Chiara Grisanzio, Matthew L Freedman.
Genes Cancer, 2011 Jul 23; 1(6). PMID: 21779458    Free PMC article.
Enhanced suicidal erythrocyte death in mice carrying a loss-of-function mutation of the adenomatous polyposis coli gene.
Syed M Qadri, Hasan Mahmud, +7 authors, Florian Lang.
J Cell Mol Med, 2011 Jul 26; 16(5). PMID: 21781276    Free PMC article.
Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells.
Desheng Lu, Michael Y Choi, +3 authors, Dennis A Carson.
Proc Natl Acad Sci U S A, 2011 Jul 27; 108(32). PMID: 21788521    Free PMC article.
Highly Cited.
Analysis of molecular aberrations of Wnt pathway gladiators in colorectal cancer in the Kashmiri population.
A Syed Sameer, Zaffar A Shah, +2 authors, Mushtaq A Siddiqi.
Hum Genomics, 2011 Aug 03; 5(5). PMID: 21807601    Free PMC article.
Inhibition of Wnt signaling by cucurbitacin B in breast cancer cells: reduction of Wnt-associated proteins and reduced translocation of galectin-3-mediated β-catenin to the nucleus.
Sumana Dakeng, Suwit Duangmano, +3 authors, Pimpicha Patmasiriwat.
J Cell Biochem, 2011 Aug 26; 113(1). PMID: 21866566    Free PMC article.
WIF1 is a frequent target for epigenetic silencing in squamous cell carcinoma of the cervix.
Amber L Delmas, Bridget M Riggs, +8 authors, Kevin D Brown.
Carcinogenesis, 2011 Aug 30; 32(11). PMID: 21873353    Free PMC article.
The beta-catenin binding protein ICAT modulates androgen receptor activity.
Ming Zhuo, Chunfang Zhu, +2 authors, Zijie Sun.
Mol Endocrinol, 2011 Sep 03; 25(10). PMID: 21885566    Free PMC article.
Wnt gene loss in flatworms.
Nick Riddiford, Peter D Olson.
Dev Genes Evol, 2011 Sep 06; 221(4). PMID: 21892738
Increased β-catenin/Tcf signaling in pilocytic astrocytomas: a comparative study to distinguish pilocytic astrocytomas from low-grade diffuse astrocytomas.
Gangadhara Reddy Sareddy, Khamushavalli Geeviman, +3 authors, Phanithi Prakash Babu.
Neurochem Res, 2011 Sep 17; 37(1). PMID: 21922255
Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism.
Sripathi M Sureban, Randal May, +6 authors, Courtney W Houchen.
J Nanobiotechnology, 2011 Sep 21; 9. PMID: 21929751    Free PMC article.
Mammalian Ino80 mediates double-strand break repair through its role in DNA end strand resection.
Anastas Gospodinov, Thomas Vaissiere, +3 authors, Zdenko Herceg.
Mol Cell Biol, 2011 Sep 29; 31(23). PMID: 21947284    Free PMC article.
Functional dissection of phosphorylation of Disheveled in Drosophila.
Wang A Yanfeng, Hebist Berhane, +3 authors, Marek Mlodzik.
Dev Biol, 2011 Oct 04; 360(1). PMID: 21963539    Free PMC article.
Genome-wide analysis of a Wnt1-regulated transcriptional network implicates neurodegenerative pathways.
Eric M Wexler, Ezra Rosen, +4 authors, Daniel H Geschwind.
Sci Signal, 2011 Oct 06; 4(193). PMID: 21971039    Free PMC article.
Inhibition of β-catenin signaling by nongenomic action of orphan nuclear receptor Nur77.
Z Sun, X Cao, +15 authors, X-K Zhang.
Oncogene, 2011 Oct 12; 31(21). PMID: 21986938    Free PMC article.
E-cadherin/β-catenin complex and the epithelial barrier.
Xinrui Tian, Zhuola Liu, +6 authors, Guoping Zheng.
J Biomed Biotechnol, 2011 Oct 19; 2011. PMID: 22007144    Free PMC article.
Highly Cited. Review.
Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa.
Stefan Enroth, Alvaro Rada-Iglesisas, +5 authors, Claes Wadelius.
BMC Cancer, 2011 Oct 21; 11. PMID: 22011431    Free PMC article.
FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis.
Nu Zhang, Ping Wei, +13 authors, Suyun Huang.
Cancer Cell, 2011 Oct 22; 20(4). PMID: 22014570    Free PMC article.
Highly Cited.
Wnt/β-catenin expression does not correlate with serum alkaline phosphatase concentration in canine osteosarcoma patients.
Caroline M Piskun, Anantharaman Muthuswamy, +2 authors, Timothy J Stein.
PLoS One, 2011 Oct 25; 6(10). PMID: 22022527    Free PMC article.
GLIPR1 suppresses prostate cancer development through targeted oncoprotein destruction.
Likun Li, Chengzhen Ren, +9 authors, Timothy C Thompson.
Cancer Res, 2011 Oct 26; 71(24). PMID: 22025562    Free PMC article.
Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway.
Weiru Xu, Hongsheng Lin, +8 authors, Liangliang Yang.
J Exp Clin Cancer Res, 2011 Oct 29; 30. PMID: 22032476    Free PMC article.
NOTCH1 regulates migration and invasion of skin cancer cells by E-cadherin repression.
Zhipeng Wang, Linna Liu, +8 authors, Yukun Wang.
Mol Cell Biochem, 2011 Nov 01; 362(1-2). PMID: 22038626
Inhibition of GSK3β improves hippocampus-dependent learning and rescues neurogenesis in a mouse model of fragile X syndrome.
Weixiang Guo, Adeline C Murthy, +4 authors, Xinyu Zhao.
Hum Mol Genet, 2011 Nov 04; 21(3). PMID: 22048960    Free PMC article.
Update on Wnt signaling in bone cell biology and bone disease.
David G Monroe, Meghan E McGee-Lawrence, Merry Jo Oursler, Jennifer J Westendorf.
Gene, 2011 Nov 15; 492(1). PMID: 22079544    Free PMC article.
Highly Cited. Review.
PROP1 and CTNNB1 expression in adamantinomatous craniopharyngiomas with or without β-catenin mutations.
Carolina M G Cani, Hamilton Matushita, +4 authors, Berenice B Mendonça.
Clinics (Sao Paulo), 2011 Nov 17; 66(11). PMID: 22086512    Free PMC article.
Beta-catenin accelerates human papilloma virus type-16 mediated cervical carcinogenesis in transgenic mice.
Gülay Bulut, Shannon Fallen, +8 authors, Aykut Üren.
PLoS One, 2011 Nov 17; 6(11). PMID: 22087269    Free PMC article.
Distinct association between aberrant methylation of Wnt inhibitors and genetic alterations in acute myeloid leukaemia.
H-A Hou, Y-Y Kuo, +9 authors, H-F Tien.
Br J Cancer, 2011 Nov 19; 105(12). PMID: 22095226    Free PMC article.
Amer2 protein is a novel negative regulator of Wnt/β-catenin signaling involved in neuroectodermal patterning.
Astrid S Pfister, Kristina Tanneberger, Alexandra Schambony, Jürgen Behrens.
J Biol Chem, 2011 Dec 01; 287(3). PMID: 22128170    Free PMC article.
Synergy analysis reveals association between insulin signaling and desmoplakin expression in palmitate treated HepG2 cells.
Xuewei Wang, Aritro Nath, +3 authors, Christina Chan.
PLoS One, 2011 Dec 02; 6(11). PMID: 22132232    Free PMC article.
Re-expression of miR-21 contributes to migration and invasion by inducing epithelial-mesenchymal transition consistent with cancer stem cell characteristics in MCF-7 cells.
Mingli Han, Manran Liu, +6 authors, Chengyi Wu.
Mol Cell Biochem, 2011 Dec 22; 363(1-2). PMID: 22187223
Design of triazole-stapled BCL9 α-helical peptides to target the β-catenin/B-cell CLL/lymphoma 9 (BCL9) protein-protein interaction.
Steven A Kawamoto, Adriana Coleska, +3 authors, Shaomeng Wang.
J Med Chem, 2011 Dec 27; 55(3). PMID: 22196480    Free PMC article.
Personalized therapy in endometrial cancer: challenges and opportunities.
Shannon N Westin, Russell R Broaddus.
Cancer Biol Ther, 2011 Dec 27; 13(1). PMID: 22198566    Free PMC article.
Alternative Splicing of Fibroblast Growth Factor Receptor IgIII Loops in Cancer.
Klaus Holzmann, Thomas Grunt, +6 authors, Brigitte Marian.
J Nucleic Acids, 2011 Dec 29; 2012. PMID: 22203889    Free PMC article.
Implications of protein post-translational modifications in IBD.
Stefan F Ehrentraut, Sean P Colgan.
Inflamm Bowel Dis, 2012 Jan 10; 18(7). PMID: 22223542    Free PMC article.
WNT7A regulates tumor growth and progression in ovarian cancer through the WNT/β-catenin pathway.
Shin Yoshioka, Mandy L King, +7 authors, Kanako Hayashi.
Mol Cancer Res, 2012 Jan 11; 10(3). PMID: 22232518    Free PMC article.
A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins.
Katrin Luckert, Taranjit S Gujral, +5 authors, Oliver Pötz.
Sci Signal, 2012 Jan 12; 5(206). PMID: 22234610    Free PMC article.
Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis.
Payam Shahi, Dongsu Park, +9 authors, David M Spencer.
PLoS One, 2012 Feb 04; 7(1). PMID: 22303459    Free PMC article.
Wnt signaling pathways in urological cancers: past decades and still growing.
Shahana Majid, Sharanjot Saini, Rajvir Dahiya.
Mol Cancer, 2012 Feb 14; 11. PMID: 22325146    Free PMC article.
Expression and clinical significance of Wnt players and survivin in pituitary tumours.
Robert Formosa, Mark Gruppetta, +4 authors, Josanne Vassallo.
Endocr Pathol, 2012 Feb 14; 23(2). PMID: 22327960
Epigenetic silencing of sFRP1 activates the canonical Wnt pathway and contributes to increased cell growth and proliferation in hepatocellular carcinoma.
Pushpinder Kaur, Samson Mani, +4 authors, Zdenko Herceg.
Tumour Biol, 2012 Feb 22; 33(2). PMID: 22351518
Integrative analyses of conserved WNT clusters and their co-operative behaviour in human breast cancer.
Qurrat-Ul-Ain, Umair Seemab, Sulaman Nawaz, Sajid Rashid.
Bioinformation, 2012 Feb 23; 7(7). PMID: 22355234    Free PMC article.
Dynein light chain 1 functions in somatic cyst cells regulate spermatogonial divisions in Drosophila.
Prakash Joti, Anindya Ghosh-Roy, Krishanu Ray.
Sci Rep, 2012 Feb 23; 1. PMID: 22355688    Free PMC article.
Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2.
Rama Kamesh Bikkavilli, Craig C Malbon.
J Cell Sci, 2012 Feb 24; 125(Pt 10). PMID: 22357953    Free PMC article.
Transcriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myeloma.
Kinga A Kocemba, Richard W J Groen, +4 authors, Steven T Pals.
PLoS One, 2012 Mar 01; 7(2). PMID: 22363428    Free PMC article.
Wnt signalling pathway parameters for mammalian cells.
Chin Wee Tan, Bruce S Gardiner, +3 authors, Antony W Burgess.
PLoS One, 2012 Mar 01; 7(2). PMID: 22363759    Free PMC article.
Loss of secreted frizzled-related protein 4 correlates with an aggressive phenotype and predicts poor outcome in ovarian cancer patients.
Francis Jacob, Kristjan Ukegjini, +10 authors, Viola A Heinzelmann-Schwarz.
PLoS One, 2012 Mar 01; 7(2). PMID: 22363760    Free PMC article.
Krüppel-like factor 4 regulates intestinal epithelial cell morphology and polarity.
Tianxin Yu, Xi Chen, +5 authors, Chunming Liu.
PLoS One, 2012 Mar 03; 7(2). PMID: 22384261    Free PMC article.
β-Catenin Signalling in Glioblastoma Multiforme and Glioma-Initiating Cells.
Mireia Nager, Deepshikha Bhardwaj, +3 authors, Judit Herreros.
Chemother Res Pract, 2012 Mar 09; 2012. PMID: 22400111    Free PMC article.
Exploring molecular genetics of bladder cancer: lessons learned from mouse models.
Imran Ahmad, Owen J Sansom, Hing Y Leung.
Dis Model Mech, 2012 Mar 17; 5(3). PMID: 22422829    Free PMC article.
Molecular alterations associated with osteosarcoma development.
Kosei Ando, Kanji Mori, +3 authors, Dominique Heymann.
Sarcoma, 2012 Mar 27; 2012. PMID: 22448123    Free PMC article.
Role of the transcription factor Bcl11b in development and lymphomagenesis.
Ryo Kominami.
Proc Jpn Acad Ser B Phys Biol Sci, 2012 Mar 28; 88(3). PMID: 22450536    Free PMC article.
Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse.
Sara Khalil, Grace A Tan, +2 authors, Louise R Howe.
PLoS One, 2012 Mar 30; 7(3). PMID: 22457761    Free PMC article.
Impact of mutant β-catenin on ABCB1 expression and therapy response in colon cancer cells.
U Stein, C Fleuter, +7 authors, W Walther.
Br J Cancer, 2012 Mar 31; 106(8). PMID: 22460269    Free PMC article.
In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system.
T Jardé, R J Evans, +5 authors, T C Dale.
Oncogene, 2012 Apr 04; 32(7). PMID: 22469981    Free PMC article.
Intracellular signaling controlled by the endosomal-exosomal pathway.
Frederik J Verweij, Jaap M Middeldorp, D Michiel Pegtel.
Commun Integr Biol, 2012 Apr 07; 5(1). PMID: 22482020    Free PMC article.
Disabled-2 (Dab2) inhibits Wnt/β-catenin signalling by binding LRP6 and promoting its internalization through clathrin.
Yong Jiang, Xi He, Philip H Howe.
EMBO J, 2012 Apr 12; 31(10). PMID: 22491013    Free PMC article.
Identification of colorectal cancer related genes with mRMR and shortest path in protein-protein interaction network.
Bi-Qing Li, Tao Huang, +2 authors, Kuo-Chen Chou.
PLoS One, 2012 Apr 13; 7(4). PMID: 22496748    Free PMC article.
Nasopharyngeal carcinoma signaling pathway: an update on molecular biomarkers.
Warut Tulalamba, Tavan Janvilisri.
Int J Cell Biol, 2012 Apr 14; 2012. PMID: 22500174    Free PMC article.
Sensitive detection of pathway perturbations in cancers.
Corban G Rivera, Brett M Tyler, T M Murali.
BMC Bioinformatics, 2012 May 02; 13 Suppl 3. PMID: 22536907    Free PMC article.
β-Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3'-UTR and interacts with HuR in colon cancer cells.
Inae Kim, Hoyun Kwak, +2 authors, Sunjoo Jeong.
Nucleic Acids Res, 2012 May 01; 40(14). PMID: 22544606    Free PMC article.
Arsenic and chromium in drinking water promote tumorigenesis in a mouse colitis-associated colorectal cancer model and the potential mechanism is ROS-mediated Wnt/β-catenin signaling pathway.
Xin Wang, Ardhendu K Mandal, +11 authors, Xianglin Shi.
Toxicol Appl Pharmacol, 2012 May 04; 262(1). PMID: 22552367    Free PMC article.
Chemopreventive sphingadienes downregulate Wnt signaling via a PP2A/Akt/GSK3β pathway in colon cancer.
Ashok Kumar, Ashok K Pandurangan, +5 authors, Julie D Saba.
Carcinogenesis, 2012 May 15; 33(9). PMID: 22581840    Free PMC article.
MENA is a transcriptional target of the Wnt/beta-catenin pathway.
Ayaz Najafov, Tuncay Seker, +5 authors, Necla Birgül-İyison.
PLoS One, 2012 May 23; 7(5). PMID: 22615875    Free PMC article.
Embryonic stem cell markers.
Wenxiu Zhao, Xiang Ji, +2 authors, Lan Ma.
Molecules, 2012 May 29; 17(6). PMID: 22634835    Free PMC article.
Chibby suppresses growth of human SW480 colon adenocarcinoma cells through inhibition of β-catenin signaling.
Victoria Fischer, Dex-Ann Brown-Grant, Feng-Qian Li.
J Mol Signal, 2012 Jun 02; 7(1). PMID: 22651859    Free PMC article.
Multiplexed protein signal pathway mapping identifies patients with rectal cancer that responds to neoadjuvant treatment.
Enzo Mammano, Francesca Galdi, +12 authors, Donato Nitti.
Clin Colorectal Cancer, 2012 Jun 05; 11(4). PMID: 22658458    Free PMC article.
Identification of proteins with potential osteogenic activity present in the water-soluble matrix proteins from Crassostrea gigas nacre using a proteomic approach.
Daniel V Oliveira, Tomé S Silva, +2 authors, Dina C Simes.
ScientificWorldJournal, 2012 Jun 06; 2012. PMID: 22666151    Free PMC article.
Signaling from the adherens junction.
Abbye E McEwen, David E Escobar, Cara J Gottardi.
Subcell Biochem, 2012 Jun 08; 60. PMID: 22674072    Free PMC article.
Molecular basis for the tissue specificity of β-catenin oncogenesis.
A Sharma, J M Sen.
Oncogene, 2012 Jun 13; 32(15). PMID: 22689057    Free PMC article.
Identifying microRNA-mRNA regulatory network in colorectal cancer by a combination of expression profile and bioinformatics analysis.
Jihong Fu, Wentao Tang, +6 authors, Long Cui.
BMC Syst Biol, 2012 Jun 19; 6. PMID: 22703586    Free PMC article.
Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin.
Brigitte Gerard, Matthew A Sanders, +2 authors, Malathy P V Shekhar.
Biochim Biophys Acta, 2012 Jun 19; 1823(10). PMID: 22705350    Free PMC article.
Knock-down of Kaiso induces proliferation and blocks granulocytic differentiation in blast crisis of chronic myeloid leukemia.
Jaime Cofre, João R L Menezes, Luciana Pizzatti, Eliana Abdelhay.
Cancer Cell Int, 2012 Jun 20; 12(1). PMID: 22709531    Free PMC article.
Pathway-based classification of cancer subtypes.
Shinuk Kim, Mark Kon, Charles DeLisi.
Biol Direct, 2012 Jul 05; 7. PMID: 22759382    Free PMC article.
Reversible modification of adenomatous polyposis coli (APC) with K63-linked polyubiquitin regulates the assembly and activity of the β-catenin destruction complex.
Hoanh Tran, Paul Polakis.
J Biol Chem, 2012 Jul 05; 287(34). PMID: 22761442    Free PMC article.
Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN.
Mingli Han, Manran Liu, +7 authors, Chengyi Wu.
PLoS One, 2012 Jul 05; 7(6). PMID: 22761812    Free PMC article.
Highly Cited.
Implication of microsatellite instability in human gastric cancers.
Upasana Shokal, Prakash C Sharma.
Indian J Med Res, 2012 Jul 10; 135(5). PMID: 22771588    Free PMC article.
The CRM1 nuclear export protein in normal development and disease.
Kevin T Nguyen, Michael P Holloway, Rachel A Altura.
Int J Biochem Mol Biol, 2012 Jul 10; 3(2). PMID: 22773955    Free PMC article.
A WNT/p21 circuit directed by the C-clamp, a sequence-specific DNA binding domain in TCFs.
Nate P Hoverter, Ju-Hui Ting, +2 authors, Marian L Waterman.
Mol Cell Biol, 2012 Jul 11; 32(18). PMID: 22778133    Free PMC article.
Adenomatous polyposis coli interacts with flap endonuclease 1 to block its nuclear entry and function.
Aruna S Jaiswal, Melissa L Armas, +2 authors, Satya Narayan.
Neoplasia, 2012 Jul 13; 14(6). PMID: 22787431    Free PMC article.
Carboxypeptidase E: a negative regulator of the canonical Wnt signaling pathway.
N Skalka, M Caspi, +2 authors, R Rosin-Arbesfeld.
Oncogene, 2012 Jul 25; 32(23). PMID: 22824791    Free PMC article.
Foxm1 mediates cross talk between Kras/mitogen-activated protein kinase and canonical Wnt pathways during development of respiratory epithelium.
I-Ching Wang, Jonathan Snyder, +7 authors, Vladimir V Kalinichenko.
Mol Cell Biol, 2012 Jul 25; 32(19). PMID: 22826436    Free PMC article.
Mathematical modeling of therapeutic strategies for myeloid malignancies.
Dan Wu, Huiyu Li, +4 authors, Yi Xiao.
Pathol Oncol Res, 2012 Jul 31; 18(4). PMID: 22843097
Analysis of bacteria from intestinal tract of FAP patients for the presence of APC-like sequences.
Vladimir Holec, Sona Ciernikova, +7 authors, Vladimir Zajac.
Med Sci Monit, 2012 Aug 01; 18(8). PMID: 22847197    Free PMC article.
How the ubiquitin proteasome system regulates the regulators of transcription.
Gary Ee, Norbert Lehming.
Transcription, 2012 Aug 14; 3(5). PMID: 22885980    Free PMC article.
Association of the TCF7L2 rs12255372 (G/T) variant with type 2 diabetes mellitus in an Iranian population.
Faranak Mahmoudi Alami, Mehran Ahmadi, +4 authors, Nader Mansour Samaei.
Genet Mol Biol, 2012 Aug 14; 35(2). PMID: 22888288    Free PMC article.
Targeting of Noncanonical Wnt5a Signaling by AP-1 Blocker Dominant-Negative Jun When It Inhibits Skin Carcinogenesis.
Moon-Il Kang, Alyson R Baker, +3 authors, Nancy H Colburn.
Genes Cancer, 2012 Aug 16; 3(1). PMID: 22893789    Free PMC article.
Amer2 protein interacts with EB1 protein and adenomatous polyposis coli (APC) and controls microtubule stability and cell migration.
Astrid S Pfister, Michel V Hadjihannas, +2 authors, Jürgen Behrens.
J Biol Chem, 2012 Aug 18; 287(42). PMID: 22898821    Free PMC article.
Cell wars: regulation of cell survival and proliferation by cell competition.
Silvia Vivarelli, Laura Wagstaff, Eugenia Piddini.
Essays Biochem, 2012 Aug 30; 53. PMID: 22928509    Free PMC article.
Loss of SFRP1 promotes ductal branching in the murine mammary gland.
Kelly J Gauger, Akihiko Shimono, Giovanna M Crisi, Sallie Smith Schneider.
BMC Dev Biol, 2012 Aug 30; 12. PMID: 22928951    Free PMC article.
Epigenetic modulation by methionine deficiency attenuates the potential for gastric cancer cell dissemination.
Luigina Graziosi, Andrea Mencarelli, +8 authors, Stefano Fiorucci.
J Gastrointest Surg, 2012 Sep 06; 17(1). PMID: 22948834
Immunohistochemical study of β-catenin and functionally related molecular markers in tongue squamous cell carcinoma and its correlation with cellular proliferation.
Xia Yun, Lihong Wang, +2 authors, Yoshio Miki.
Oncol Lett, 2010 May 01; 1(3). PMID: 22966322    Free PMC article.
miRNA expression profile in primary gastric cancers and paired lymph node metastases indicates that miR-10a plays a role in metastasis from primary gastric cancer to lymph nodes.
Weidong Chen, Zhaoqing Tang, +5 authors, Xinyu Qin.
Exp Ther Med, 2012 Sep 13; 3(2). PMID: 22969895    Free PMC article.
Nuclear Factor kappa B is central to Marek's disease herpesvirus induced neoplastic transformation of CD30 expressing lymphocytes in-vivo.
Shyamesh Kumar, Dusan Kunec, +6 authors, Shane C Burgess.
BMC Syst Biol, 2012 Sep 18; 6. PMID: 22979947    Free PMC article.
Wnt pathway activation predicts increased risk of tumor recurrence in patients with stage I nonsmall cell lung cancer.
Mark Shapiro, Gal Akiri, +5 authors, Stuart A Aaronson.
Ann Surg, 2012 Sep 27; 257(3). PMID: 23011390    Free PMC article.
Wnt/beta-catenin signaling and small molecule inhibitors.
Andrey Voronkov, Stefan Krauss.
Curr Pharm Des, 2012 Sep 29; 19(4). PMID: 23016862    Free PMC article.
Highly Cited. Review.
Role of β-catenin expression in paediatric mesenchymal lesions: a tissue microarray-based immunohistochemical study.
A Santoro, G Pannone, +5 authors, V Donofrio.
Eur J Histochem, 2012 Oct 03; 56(3). PMID: 23027341    Free PMC article.
Activating mutations in β-catenin in colon cancer cells alter their interaction with macrophages; the role of snail.
Pawan Kaler, Leonard Augenlicht, Lidija Klampfer.
PLoS One, 2012 Oct 03; 7(9). PMID: 23029025    Free PMC article.
Secreted frizzled-related protein 4 expression is positively associated with responsiveness to cisplatin of ovarian cancer cell lines in vitro and with lower tumour grade in mucinous ovarian cancers.
Uttara Saran, Frank Arfuso, Nikolajs Zeps, Arunasalam Dharmarajan.
BMC Cell Biol, 2012 Oct 09; 13. PMID: 23039795    Free PMC article.
CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of β-catenin in carcinoma cells.
Satomi Chigita, Tsuyoshi Sugiura, +4 authors, Kanemitsu Shirasuna.
Int J Oncol, 2012 Oct 19; 41(6). PMID: 23076981    Free PMC article.
Pleiotropic function of SRY-related HMG box transcription factor 4 in regulation of tumorigenesis.
Seyed Mehdi Jafarnejad, Gholamreza Safaee Ardekani, Mazyar Ghaffari, Gang Li.
Cell Mol Life Sci, 2012 Oct 20; 70(15). PMID: 23080209
Characterization of ectonucleotidases in human medulloblastoma cell lines: ecto-5'NT/CD73 in metastasis as potential prognostic factor.
Angélica Regina Cappellari, Liliana Rockenbach, +8 authors, Ana Maria liveira Battastini.
PLoS One, 2012 Oct 25; 7(10). PMID: 23094051    Free PMC article.
Galectin-1 and Galectin-3 Mediate Protocadherin-24-Dependent Membrane Localization of β-catenin in Colon Cancer Cell Line HCT116.
Rui Ose, Osamu Oharaa, Takahiro Nagase.
Curr Chem Genomics, 2012 Nov 02; 6. PMID: 23115611    Free PMC article.
CD73-generated adenosine: orchestrating the tumor-stroma interplay to promote cancer growth.
Bertrand Allard, Martin Turcotte, John Stagg.
J Biomed Biotechnol, 2012 Nov 06; 2012. PMID: 23125525    Free PMC article.
Somatic MED12 mutations in uterine leiomyosarcoma and colorectal cancer.
K Kämpjärvi, N Mäkinen, +16 authors, P Vahteristo.
Br J Cancer, 2012 Nov 08; 107(10). PMID: 23132392    Free PMC article.
Epigenetic alterations involved in cancer stem cell reprogramming.
Purificación Muñoz, Maria S Iliou, Manel Esteller.
Mol Oncol, 2012 Nov 13; 6(6). PMID: 23141800    Free PMC article.
Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways.
Jian Huang, Michelle Nguyen-McCarty, +2 authors, Peter S Klein.
Nat Med, 2012 Nov 13; 18(12). PMID: 23142822    Free PMC article.
Highly Cited.
Constitutive β-catenin signaling by the viral chemokine receptor US28.
Ellen V Langemeijer, Erik Slinger, +7 authors, Martine J Smit.
PLoS One, 2012 Nov 13; 7(11). PMID: 23145028    Free PMC article.
Dishevelled3 is a novel arginine methyl transferase substrate.
Rama Kamesh Bikkavilli, Sreedevi Avasarala, +4 authors, Robert A Winn.
Sci Rep, 2012 Nov 15; 2. PMID: 23150776    Free PMC article.
Pharmacological inhibition of GSK3 attenuates DNA damage-induced apoptosis via reduction of p53 mitochondrial translocation and Bax oligomerization in neuroblastoma SH-SY5Y cells.
Patchara Ngok-Ngam, Piyajit Watcharasit, Apinya Thiantanawat, Jutamaad Satayavivad.
Cell Mol Biol Lett, 2012 Nov 20; 18(1). PMID: 23161404    Free PMC article.
Evidence for possible non-canonical pathway(s) driven early-onset colorectal cancer in India.
Ratheesh Raman, Viswakalyan Kotapalli, +13 authors, Murali Bashyam.
Mol Carcinog, 2012 Nov 22; 53 Suppl 1. PMID: 23168910    Free PMC article.
MYBL2 is a substrate of GSK3-like kinase BIN2 and acts as a corepressor of BES1 in brassinosteroid signaling pathway in Arabidopsis.
Huaxun Ye, Lei Li, Hongqing Guo, Yanhai Yin.
Proc Natl Acad Sci U S A, 2012 Nov 22; 109(49). PMID: 23169658    Free PMC article.
Effects of molecular crowding on the dynamics of intrinsically disordered proteins.
Elio A Cino, Mikko Karttunen, Wing-Yiu Choy.
PLoS One, 2012 Nov 29; 7(11). PMID: 23189168    Free PMC article.
Tankyrase-targeted therapeutics: expanding opportunities in the PARP family.
Jenna L Riffell, Christopher J Lord, Alan Ashworth.
Nat Rev Drug Discov, 2012 Dec 01; 11(12). PMID: 23197039
Highly Cited. Review.
Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes.
Philip T T Ly, Yili Wu, +8 authors, Weihong Song.
J Clin Invest, 2012 Dec 04; 123(1). PMID: 23202730    Free PMC article.
Highly Cited.
Wnt/ß-catenin: a new therapeutic approach to acute myeloid leukemia.
Y Kim, S Thanendrarajan, I G H Schmidt-Wolf.
Leuk Res Treatment, 2011 Jan 01; 2011. PMID: 23213543    Free PMC article.
The way Wnt works: components and mechanism.
Kenyi Saito-Diaz, Tony W Chen, +4 authors, Ethan Lee.
Growth Factors, 2012 Dec 22; 31(1). PMID: 23256519    Free PMC article.
Highly Cited. Review.
SOX9 regulates low density lipoprotein receptor-related protein 6 (LRP6) and T-cell factor 4 (TCF4) expression and Wnt/β-catenin activation in breast cancer.
Hongyun Wang, Lingfeng He, +4 authors, Xin Yuan.
J Biol Chem, 2013 Jan 12; 288(9). PMID: 23306204    Free PMC article.
Lung cancer-initiating cells: a novel target for cancer therapy.
Brian J Morrison, John C Morris, Jason C Steel.
Target Oncol, 2013 Jan 15; 8(3). PMID: 23314952    Free PMC article.
More than two decades of Apc modeling in rodents.
Maged Zeineldin, Kristi L Neufeld.
Biochim Biophys Acta, 2013 Jan 22; 1836(1). PMID: 23333833    Free PMC article.
Estrogen and progesterone together expand murine endometrial epithelial progenitor cells.
Deanna M Janzen, Donghui Cheng, +6 authors, Sanaz Memarzadeh.
Stem Cells, 2013 Jan 24; 31(4). PMID: 23341289    Free PMC article.
Phosphorylation of Dishevelled by protein kinase RIPK4 regulates Wnt signaling.
XiaoDong Huang, James C McGann, +13 authors, Vishva M Dixit.
Science, 2013 Feb 02; 339(6126). PMID: 23371553    Free PMC article.
The effectiveness of cucurbitacin B in BRCA1 defective breast cancer cells.
Moltira Promkan, Sumana Dakeng, +2 authors, Pimpicha Patmasiriwat.
PLoS One, 2013 Feb 09; 8(2). PMID: 23393598    Free PMC article.
miR-375 regulates rat alveolar epithelial cell trans-differentiation by inhibiting Wnt/β-catenin pathway.
Yang Wang, Chaoqun Huang, +5 authors, Lin Liu.
Nucleic Acids Res, 2013 Feb 12; 41(6). PMID: 23396279    Free PMC article.
miR-92b controls glioma proliferation and invasion through regulating Wnt/beta-catenin signaling via Nemo-like kinase.
Kun Wang, Xuan Wang, +8 authors, Yirong Wang.
Neuro Oncol, 2013 Feb 19; 15(5). PMID: 23416699    Free PMC article.
Loss of WIF-1 and Wnt5a expression is related to aggressiveness of sporadic breast cancer in Tunisian patients.
Fatma Trifa, Sondes Karray-Chouayekh, +6 authors, Raja Mokdad-Gargouri.
Tumour Biol, 2013 Feb 19; 34(3). PMID: 23417837
Colorectal cancer: a researcher's perspective of the molecular angel's gone eccentric in the Vale of Kashmir.
Aga Syed Sameer.
Tumour Biol, 2013 Feb 19; 34(3). PMID: 23417859
The implications of cancer stem cells for cancer therapy.
Wenjing Jiang, Jianhua Peng, +2 authors, Kunlin Jin.
Int J Mol Sci, 2013 Feb 28; 13(12). PMID: 23443123    Free PMC article.
Expression of fibroblast growth factor 19 is associated with recurrence and poor prognosis of hepatocellular carcinoma.
Jiyeon Hyeon, Soomin Ahn, +2 authors, Cheol-Keun Park.
Dig Dis Sci, 2013 Mar 05; 58(7). PMID: 23456506
Regulation of Wnt4 in chronic obstructive pulmonary disease.
Andrew L Durham, Alistair McLaren, +5 authors, Ian M Adcock.
FASEB J, 2013 Mar 07; 27(6). PMID: 23463699    Free PMC article.
Dkk-3, a secreted wnt antagonist, suppresses tumorigenic potential and pulmonary metastasis in osteosarcoma.
Carol H Lin, Yi Guo, +8 authors, Bang H Hoang.
Sarcoma, 2013 Mar 12; 2013. PMID: 23476112    Free PMC article.
Pharmacological modulation of beta-catenin and its applications in cancer therapy.
Ravi Thakur, Durga Prasad Mishra.
J Cell Mol Med, 2013 Mar 16; 17(4). PMID: 23490077    Free PMC article.
Association of single nucleotide polymorphisms in Wnt signaling pathway genes with breast cancer in Saudi patients.
Mohammad Saud Alanazi, Narasimha Reddy Parine, +3 authors, Zahid Khan.
PLoS One, 2013 Mar 22; 8(3). PMID: 23516639    Free PMC article.
CTNNB1, AXIN1 and APC expression analysis of different medulloblastoma variants.
Roseli da Silva, Suely K N Marie, +4 authors, Sueli M Oba-Shinjo.
Clinics (Sao Paulo), 2013 Mar 26; 68(2). PMID: 23525311    Free PMC article.
The role of aberrant promoter hypermethylation of DACT1 in bladder urothelial carcinoma.
Huan Cheng, Zhonglei Deng, +2 authors, Jiantang Su.
J Biomed Res, 2013 Apr 05; 26(5). PMID: 23554767    Free PMC article.
FOXQ1, a novel target of the Wnt pathway and a new marker for activation of Wnt signaling in solid tumors.
Jon Christensen, Susanne Bentz, +2 authors, Pascale Anderle.
PLoS One, 2013 Apr 05; 8(3). PMID: 23555880    Free PMC article.
Understanding phenotypic variation in rodent models with germline Apc mutations.
Maged Zeineldin, Kristi L Neufeld.
Cancer Res, 2013 Apr 13; 73(8). PMID: 23580574    Free PMC article.
Iron and cancer: more ore to be mined.
Suzy V Torti, Frank M Torti.
Nat Rev Cancer, 2013 Apr 19; 13(5). PMID: 23594855    Free PMC article.
Highly Cited. Review.
Knockdown of FRAT1 expression by RNA interference inhibits human glioblastoma cell growth, migration and invasion.
Geng Guo, Dong Kuai, +13 authors, Yuhong Guo.
PLoS One, 2013 Apr 25; 8(4). PMID: 23613813    Free PMC article.
Carriers of a novel frame-shift insertion in WNT16a possess elevated pancreatic expression of TCF7L2.
Eric W Howard, Latonya F Been, +4 authors, Dharambir K Sanghera.
BMC Genet, 2013 Apr 27; 14. PMID: 23617586    Free PMC article.
Prognostic Significance of BCL9 Expression in Hepatocellular Carcinoma.
Jiyeon Hyeon, Soomin Ahn, +2 authors, Cheol-Keun Park.
Korean J Pathol, 2013 May 15; 47(2). PMID: 23667372    Free PMC article.
Phyllanthus Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NFκB, and Hypoxia).
Yin-Quan Tang, Indubala Jaganath, Rishya Manikam, Shamala Devi Sekaran.
Evid Based Complement Alternat Med, 2013 May 22; 2013. PMID: 23690850    Free PMC article.
N-glycosylation induces the CTHRC1 protein and drives oral cancer cell migration.
Gangli Liu, Pritam K Sengupta, +5 authors, Maria A Kukuruzinska.
J Biol Chem, 2013 May 25; 288(28). PMID: 23703614    Free PMC article.
Combination of selenium and green tea improves the efficacy of chemoprevention in a rat colorectal cancer model by modulating genetic and epigenetic biomarkers.
Ying Hu, Graeme H McIntosh, +3 authors, Graeme P Young.
PLoS One, 2013 May 30; 8(5). PMID: 23717604    Free PMC article.
Colorectal cancer: molecular mutations and polymorphisms.
Aga Syed Sameer.
Front Oncol, 2013 May 30; 3. PMID: 23717813    Free PMC article.
Leucine zipper tumor suppressor 2 inhibits cell proliferation and regulates Lef/Tcf-dependent transcription through Akt/GSK3β signaling pathway in lung cancer.
Quan-Zhe Cui, Zhong-Ping Tang, +4 authors, En-Hua Wang.
J Histochem Cytochem, 2013 Jun 14; 61(9). PMID: 23761130    Free PMC article.
Inhibition of the Wnt palmitoyltransferase porcupine suppresses cell growth and downregulates the Wnt/β-catenin pathway in gastric cancer.
Min-Li Mo, Meng-Ru Li, +3 authors, Hai-Meng Zhou.
Oncol Lett, 2013 Jun 14; 5(5). PMID: 23761839    Free PMC article.
Haplotype association analysis of genes within the WNT signalling pathways in diabetic nephropathy.
David H Kavanagh, David A Savage, +5 authors, Warren 3/UK GoKinD Study Group.
BMC Nephrol, 2013 Jun 20; 14. PMID: 23777469    Free PMC article.
The miR-310/13 cluster antagonizes β-catenin function in the regulation of germ and somatic cell differentiation in the Drosophila testis.
Raluca Pancratov, Felix Peng, +8 authors, Ramanuj DasgGupta.
Development, 2013 Jul 04; 140(14). PMID: 23821034    Free PMC article.
Bcl-w Enhances Mesenchymal Changes and Invasiveness of Glioblastoma Cells by Inducing Nuclear Accumulation of β-Catenin.
Woo Sang Lee, Eun Young Woo, +4 authors, In Hwa Bae.
PLoS One, 2013 Jul 05; 8(6). PMID: 23826359    Free PMC article.
S-adenosylmethionine-induced adipogenesis is accompanied by suppression of Wnt/β-catenin and Hedgehog signaling pathways.
Yang Liu, Wentao Lv, +9 authors, Jingdong Yin.
Mol Cell Biochem, 2013 Jul 31; 382(1-2). PMID: 23896663
Lung cancer stem cells: a biological and clinical perspective.
Ana Koren, Helena Motaln, Tanja Cufer.
Cell Oncol (Dordr), 2013 Aug 01; 36(4). PMID: 23900738
Targeting the Wnt pathway in synovial sarcoma models.
Whitney Barham, Andrea L Frump, +11 authors, Josiane E Eid.
Cancer Discov, 2013 Aug 08; 3(11). PMID: 23921231    Free PMC article.
Deletion of a single β-catenin allele in osteocytes abolishes the bone anabolic response to loading.
Behzad Javaheri, Amber Rath Stern, +5 authors, Mark L Johnson.
J Bone Miner Res, 2013 Aug 10; 29(3). PMID: 23929793    Free PMC article.
Effects of fertility on gene expression and function of the bovine endometrium.
Megan A Minten, Todd R Bilby, +9 authors, Thomas E Spencer.
PLoS One, 2013 Aug 14; 8(8). PMID: 23940519    Free PMC article.
Enhancer of zeste homolog 2 activates wnt signaling through downregulating CXXC finger protein 4.
H Lu, J Sun, +7 authors, H Jin.
Cell Death Dis, 2013 Aug 21; 4. PMID: 23949225    Free PMC article.
The anticancer effect of fucoidan in PC-3 prostate cancer cells.
Hye-Jin Boo, Ji-Young Hong, +8 authors, Hee-Kyoung Kang.
Mar Drugs, 2013 Aug 24; 11(8). PMID: 23966032    Free PMC article.
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
Patricio Godoy, Nicola J Hewitt, +90 authors, Jan G Hengstler.
Arch Toxicol, 2013 Aug 27; 87(8). PMID: 23974980    Free PMC article.
Highly Cited. Review.
Procalcitonin beyond the acute phase: novel biomediator properties?
Carolina Panico, Eric Nylen.
BMC Med, 2013 Aug 30; 11. PMID: 23984981    Free PMC article.
The tumor suppressor LKB1 antagonizes WNT signaling pathway through modulating GSK3β activity in cell growth of esophageal carcinoma.
Kai Liu, Yue Luo, +3 authors, Wei-Yu Shen.
Tumour Biol, 2013 Sep 12; 35(2). PMID: 24022664
Targeting Wnt-Frizzled signaling in cardiovascular diseases.
Saumya Pandey, Chandravati.
Mol Biol Rep, 2013 Sep 24; 40(10). PMID: 24057182
Norcantharidin, derivative of cantharidin, for cancer stem cells.
Chen-Hsi Hsieh, K S Clifford Chao, Hui-Fen Liao, Yu-Jen Chen.
Evid Based Complement Alternat Med, 2013 Sep 28; 2013. PMID: 24073010    Free PMC article.
Cancer stem cells and therapeutic targets: an emerging field for cancer treatment.
Arokia Priyanka Vaz, Moorthy P Ponnusamy, Surinder K Batra.
Drug Deliv Transl Res, 2013 Oct 01; 3(2). PMID: 24077517    Free PMC article.
Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish.
Alexander J Valvezan, Jian Huang, +2 authors, Peter S Klein.
Dis Model Mech, 2013 Oct 05; 7(1). PMID: 24092877    Free PMC article.
Synthesis, characterization, and evaluation of a novel inhibitor of WNT/β-catenin signaling pathway.
Zhao Yan, Zhongling Zhu, +5 authors, Yuheng Deng.
Mol Cancer, 2013 Oct 09; 12(1). PMID: 24098916    Free PMC article.
Esculetin suppresses proliferation of human colon cancer cells by directly targeting β-catenin.
Sung-Young Lee, Tae-Gyu Lim, +9 authors, Zigang Dong.
Cancer Prev Res (Phila), 2013 Oct 10; 6(12). PMID: 24104353    Free PMC article.
Human placental trophoblast invasion and differentiation: a particular focus on Wnt signaling.
Martin Knöfler, Jürgen Pollheimer.
Front Genet, 2013 Oct 18; 4. PMID: 24133501    Free PMC article.
RNA interference-mediated targeting of DKK1 gene expression in Ishikawa endometrial carcinoma cells causes increased tumor cell invasion and migration.
Nuo Yi, Qin-Ping Liao, +4 authors, Min Liu.
Oncol Lett, 2013 Oct 19; 6(3). PMID: 24137406    Free PMC article.
Immunopurification of adenomatous polyposis coli (APC) proteins.
Kerryn L Elliott, Bruno Catimel, +4 authors, Maree C Faux.
BMC Res Notes, 2013 Oct 26; 6. PMID: 24156781    Free PMC article.
LHX6 acts as a novel potential tumour suppressor with epigenetic inactivation in lung cancer.
W-b Liu, X Jiang, +5 authors, J-y Liu.
Cell Death Dis, 2013 Oct 26; 4. PMID: 24157876    Free PMC article.
Identification of a novel role of ZMIZ2 protein in regulating the activity of the Wnt/β-catenin signaling pathway.
Suk Hyung Lee, Chunfang Zhu, +3 authors, Zijie Sun.
J Biol Chem, 2013 Nov 01; 288(50). PMID: 24174533    Free PMC article.
Colon cryptogenesis: asymmetric budding.
Chin Wee Tan, Yumiko Hirokawa, +2 authors, Antony W Burgess.
PLoS One, 2013 Nov 10; 8(10). PMID: 24205248    Free PMC article.
Indole diterpene alkaloids as novel inhibitors of the Wnt/β-catenin pathway in breast cancer cells.
Asmaa A Sallam, Nehad M Ayoub, +3 authors, Khalid A El Sayed.
Eur J Med Chem, 2013 Nov 12; 70. PMID: 24211635    Free PMC article.
Wnt/β-catenin Signaling in Normal and Cancer Stem Cells.
Kenneth C Valkenburg, Carrie R Graveel, +2 authors, Bart O Williams.
Cancers (Basel), 2011 Jan 01; 3(2). PMID: 24212796    Free PMC article.
An APC:WNT Counter-Current-Like Mechanism Regulates Cell Division Along the Human Colonic Crypt Axis: A Mechanism That Explains How APC Mutations Induce Proliferative Abnormalities That Drive Colon Cancer Development.
Bruce M Boman, Jeremy Z Fields.
Front Oncol, 2013 Nov 14; 3. PMID: 24224156    Free PMC article.
ERKed by LRRK2: a cell biological perspective on hereditary and sporadic Parkinson's disease.
Manish Verma, Erin K Steer, Charleen T Chu.
Biochim Biophys Acta, 2013 Nov 15; 1842(8). PMID: 24225420    Free PMC article.
Destabilization of heterologous proteins mediated by the GSK3β phosphorylation domain of the β-catenin protein.
Yuhan Kong, Hongyu Zhang, +17 authors, Lan Zhou.
Cell Physiol Biochem, 2013 Dec 18; 32(5). PMID: 24335169    Free PMC article.
Heparan sulfate proteoglycans and human breast cancer epithelial cell tumorigenicity.
Rachel K Okolicsanyi, Andre J van Wijnen, +3 authors, Larisa M Haupt.
J Cell Biochem, 2013 Dec 21; 115(5). PMID: 24357546    Free PMC article.
Interaction-based discovery of functionally important genes in cancers.
Dario Ghersi, Mona Singh.
Nucleic Acids Res, 2013 Dec 24; 42(3). PMID: 24362839    Free PMC article.
β-Catenin induces T-cell transformation by promoting genomic instability.
Marei Dose, Akinola Olumide Emmanuel, +13 authors, Fotini Gounari.
Proc Natl Acad Sci U S A, 2013 Dec 29; 111(1). PMID: 24371308    Free PMC article.
Current Understanding on EGFR and Wnt/β-Catenin Signaling in Glioma and Their Possible Crosstalk.
Indranil Paul, Seemana Bhattacharya, Anirban Chatterjee, Mrinal K Ghosh.
Genes Cancer, 2014 Jan 05; 4(11-12). PMID: 24386505    Free PMC article.
Highly Cited. Review.
Effects of genistein and daidzein on cell proliferation kinetics in HT29 colon cancer cells: the expression of CTNNBIP1 (β-catenin), APC (adenomatous polyposis coli) and BIRC5 (survivin).
Sandra Regina Lepri, Leonardo Campos Zanelatto, +3 authors, Mario Sergio Mantovani.
Hum Cell, 2014 Jan 07; 27(2). PMID: 24390805
Mismatch repair deficient mice show susceptibility to oxidative stress-induced intestinal carcinogenesis.
Jingshu Piao, Yoshimichi Nakatsu, +2 authors, Teruhisa Tsuzuki.
Int J Biol Sci, 2014 Jan 07; 10(1). PMID: 24391453    Free PMC article.
Drugging a stem cell compartment using Wnt3a protein as a therapeutic.
Girija R Dhamdhere, Mark Y Fang, +9 authors, Jill A Helms.
PLoS One, 2014 Jan 09; 9(1). PMID: 24400074    Free PMC article.
Establishment and characterization of 7 novel hepatocellular carcinoma cell lines from patient-derived tumor xenografts.
Hong Xin, Ke Wang, +7 authors, Xiaoran Qin.
PLoS One, 2014 Jan 15; 9(1). PMID: 24416385    Free PMC article.
p53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expression.
Sachiyo Okayama, Levy Kopelovich, +4 authors, Kotha Subbaramaiah.
J Biol Chem, 2014 Jan 24; 289(10). PMID: 24451373    Free PMC article.
Identification of two Wnt-responsive elements in the intron of RING finger protein 43 (RNF43) gene.
Norihiko Takahashi, Kiyoshi Yamaguchi, +2 authors, Yoichi Furukawa.
PLoS One, 2014 Jan 28; 9(1). PMID: 24466159    Free PMC article.
Cleavage of E-cadherin and β-catenin by calpain affects Wnt signaling and spheroid formation in suspension cultures of human pluripotent stem cells.
Sarah A Konze, Laura van Diepen, +7 authors, Falk F R Buettner.
Mol Cell Proteomics, 2014 Feb 01; 13(4). PMID: 24482122    Free PMC article.
The roles of transforming growth factor-β, Wnt, Notch and hypoxia on liver progenitor cells in primary liver tumours (Review).
Eliene Bogaerts, Femke Heindryckx, +2 authors, Hans Van Vlierberghe.
Int J Oncol, 2014 Feb 08; 44(4). PMID: 24504124    Free PMC article.
Engrailed-2 is down-regulated but also ectopically expressed in clear cell renal cell carcinoma.
Cai-yong Lai, Bin Pan, +6 authors, Ze-xuan Su.
Mol Biol Rep, 2014 Feb 18; 41(6). PMID: 24532139
Activated macrophages promote Wnt/β-catenin signaling in cholangiocarcinoma cells.
Watcharin Loilome, Pornpan Bungkanjana, +5 authors, Gregory J Riggins.
Tumour Biol, 2014 Feb 20; 35(6). PMID: 24549785    Free PMC article.
The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells.
Roberta Malaguarnera, Antonino Belfiore.
Front Endocrinol (Lausanne), 2014 Feb 20; 5. PMID: 24550888    Free PMC article.
Highly Cited. Review.
Wnt3a expression is associated with MMP-9 expression in primary tumor and metastatic site in recurrent or stage IV colorectal cancer.
Myung Ah Lee, Jin-Hee Park, +3 authors, Hee-Na Kim.
BMC Cancer, 2014 Feb 26; 14. PMID: 24564183    Free PMC article.
Genetic unraveling of colorectal cancer.
Sabha Rasool, Vamiq Rasool, +2 authors, Bhahwal Ali Shah.
Tumour Biol, 2014 Feb 28; 35(6). PMID: 24573608
Novel hepatocellular carcinoma molecules with prognostic and therapeutic potentials.
Bruna Scaggiante, Maryam Kazemi, +5 authors, Gabriele Grassi.
World J Gastroenterol, 2014 Feb 28; 20(5). PMID: 24574801    Free PMC article.
β-catenin as a prognostic factor for prostate cancer (PCa).
Andrzej Nowicki, Stanisław Sporny, Joanna Duda-Szymańska.
Cent European J Urol, 2012 Jan 01; 65(3). PMID: 24578946    Free PMC article.
Promoter methylation of SFRP3 is frequent in hepatocellular carcinoma.
Ya-Wen Lin, Yu-Lueng Shih, +3 authors, Ming-De Yan.
Dis Markers, 2014 Mar 05; 2014. PMID: 24591760    Free PMC article.
Regulation of Wnt/β-catenin signaling by posttranslational modifications.
Chenxi Gao, Gutian Xiao, Jing Hu.
Cell Biosci, 2014 Mar 07; 4(1). PMID: 24594309    Free PMC article.
Highly Cited.
Serum level of DKK-1 and its prognostic potential in non-small cell lung cancer.
Liang-liang Dong, Lu-yun Qu, +2 authors, Ying-hui Liu.
Diagn Pathol, 2014 Mar 13; 9. PMID: 24612589    Free PMC article.
Nuclear transport of galectin-3 and its therapeutic implications.
Tatsuyoshi Funasaka, Avraham Raz, Pratima Nangia-Makker.
Semin Cancer Biol, 2014 Mar 25; 27. PMID: 24657939    Free PMC article.
The involvement of AMPK/GSK3-beta signals in the control of metastasis and proliferation in hepato-carcinoma cells treated with anthocyanins extracted from Korea wild berry Meoru.
Song Yi Park, Yun-Kyoung Lee, +2 authors, Young-Min Kim.
BMC Complement Altern Med, 2014 Mar 29; 14. PMID: 24666969    Free PMC article.
[Construction and expression of nm23-H1 gene with different enzyme activities and resistant specific shRNA in eukaryotic expression vector].
Zhansheng Lu, Lili Guo, +2 authors, Qinghua Zhou.
Zhongguo Fei Ai Za Zhi, 2014 Mar 29; 17(3). PMID: 24667253    Free PMC article.
Analysis of Wnt signaling β-catenin spatial dynamics in HEK293T cells.
Chin Wee Tan, Bruce S Gardiner, +2 authors, Antony W Burgess.
BMC Syst Biol, 2014 Apr 10; 8. PMID: 24712863    Free PMC article.
Protein N-glycosylation in oral cancer: dysregulated cellular networks among DPAGT1, E-cadherin adhesion and canonical Wnt signaling.
Xaralabos Varelas, Meghan P Bouchie, Maria A Kukuruzinska.
Glycobiology, 2014 Apr 20; 24(7). PMID: 24742667    Free PMC article.
Transcriptional responses and embryotoxic effects induced by pyrene and methylpyrene in Japanese medaka (Oryzias latipes) early life stages exposed to spiked sediments.
Iris Barjhoux, Jérôme Cachot, +5 authors, Magalie Baudrimont.
Environ Sci Pollut Res Int, 2014 Apr 24; 21(24). PMID: 24756688
Circadian clock circuitry in colorectal cancer.
Gianluigi Mazzoccoli, Manlio Vinciguerra, Gennaro Papa, Ada Piepoli.
World J Gastroenterol, 2014 Apr 26; 20(15). PMID: 24764658    Free PMC article.
Chemoprevention in gastrointestinal physiology and disease. Natural products and microbiome.
Allen K Greiner, Rao V L Papineni, Shahid Umar.
Am J Physiol Gastrointest Liver Physiol, 2014 May 03; 307(1). PMID: 24789206    Free PMC article.
The expression of β-catenin in different subtypes of breast cancer and its clinical significance.
Shuguang Li, Shanshan Li, Ying Sun, Li Li.
Tumour Biol, 2014 May 08; 35(8). PMID: 24801904
Cancer stem cells: biological functions and therapeutically targeting.
Marius Eugen Ciurea, Ada Maria Georgescu, +5 authors, Anica Dricu.
Int J Mol Sci, 2014 May 14; 15(5). PMID: 24821540    Free PMC article.
Rad6 is a Potential Early Marker of Melanoma Development.
Karli Rosner, Shreelekha Adsule, +4 authors, Malathy P V Shekhar.
Transl Oncol, 2014 May 17;. PMID: 24831578    Free PMC article.
Downregulation of WIF-1 and Wnt5a in patients with colorectal carcinoma: clinical significance.
Rania Abdelmaksoud-Dammak, Imen Miladi-Abdennadher, +5 authors, Raja Mokdad-Gargouri.
Tumour Biol, 2014 May 17; 35(8). PMID: 24833087
The effects of diet induced obesity on breast cancer associated pathways in mice deficient in SFRP1.
Kelly J Gauger, Lotfi M Bassa, +4 authors, Sallie S Schneider.
Mol Cancer, 2014 Jun 03; 13. PMID: 24885183    Free PMC article.
ATP-dependent chromatin remodeling complexes as novel targets for cancer therapy.
Kimberly Mayes, Zhijun Qiu, Aiman Alhazmi, Joseph W Landry.
Adv Cancer Res, 2014 Jun 04; 121. PMID: 24889532    Free PMC article.
Nuclear adenomatous polyposis coli suppresses colitis-associated tumorigenesis in mice.
Maged Zeineldin, Matthew A Miller, Ruth Sullivan, Kristi L Neufeld.
Carcinogenesis, 2014 Jun 05; 35(8). PMID: 24894865    Free PMC article.
HBP1 promoter methylation augments the oncogenic β-catenin to correlate with prognosis in NSCLC.
Ruo-Chia Tseng, Way-Ren Huang, +3 authors, Yi-Ching Wang.
J Cell Mol Med, 2014 Jun 05; 18(9). PMID: 24895061    Free PMC article.
The CK1 Family: Contribution to Cellular Stress Response and Its Role in Carcinogenesis.
Uwe Knippschild, Marc Krüger, +6 authors, Joachim Bischof.
Front Oncol, 2014 Jun 07; 4. PMID: 24904820    Free PMC article.
Highly Cited. Review.
PCDH20 functions as a tumour-suppressor gene through antagonizing the Wnt/β-catenin signalling pathway in hepatocellular carcinoma.
J Lv, P Zhu, +5 authors, F Lu.
J Viral Hepat, 2014 Jun 10; 22(2). PMID: 24910204    Free PMC article.
PP2A inhibitors suppress migration and growth of PANC-1 pancreatic cancer cells through inhibition on the Wnt/β-catenin pathway by phosphorylation and degradation of β-catenin.
Meng-Yao Wu, Xin Xie, +7 authors, Min Tao.
Oncol Rep, 2014 Jun 14; 32(2). PMID: 24926961    Free PMC article.
Cadherin 11, a miR-675 target, induces N-cadherin expression and epithelial-mesenchymal transition in melasma.
Nan-Hyung Kim, Soo-Hyun Choi, +2 authors, Ai-Young Lee.
J Invest Dermatol, 2014 Jun 19; 134(12). PMID: 24940649
Influence of adriamycin on changes in Nanog, Oct-4, Sox2, ARID1 and Wnt5b expression in liver cancer stem cells.
Ding Sun, Lei Qin, +3 authors, Hai-Xin Qian.
World J Gastroenterol, 2014 Jun 20; 20(22). PMID: 24944491    Free PMC article.
Involvement of SET in the Wnt signaling pathway and the development of human colorectal cancer.
Lei Dong, Jianjun Zhu, +2 authors, Yao Chen.
Oncol Lett, 2014 Jun 20; 7(4). PMID: 24944693    Free PMC article.
Promoter hypermethylation of Wnt pathway inhibitors in hepatitis C virus - induced multistep hepatocarcinogenesis.
Muhammad Umer, Sohail Asif Qureshi, +4 authors, Mazhar Iqbal.
Virol J, 2014 Jun 21; 11. PMID: 24947038    Free PMC article.
Suppression of metastasis by mirtazapine via restoration of the Lin-7C/β-catenin pathway in human cancer cells.
Katsuhiro Uzawa, Atsushi Kasamatsu, +8 authors, Hideki Tanzawa.
Sci Rep, 2014 Jun 26; 4. PMID: 24961284    Free PMC article.
Emerging role of the β-catenin-PPARγ axis in the pathogenesis of colorectal cancer.
Lina Sabatino, Massimo Pancione, +5 authors, Vittorio Colantuoni.
World J Gastroenterol, 2014 Jun 27; 20(23). PMID: 24966585    Free PMC article.
Single nucleotide polymorphisms associated with colorectal cancer susceptibility and loss of heterozygosity in a Taiwanese population.
Chih-Yung Yang, Ruey-Hwa Lu, +6 authors, Chi-Hung Lin.
PLoS One, 2014 Jun 27; 9(6). PMID: 24968322    Free PMC article.
Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemia.
Smita Dandekar, Eleny Romanos-Sirakis, +9 authors, William L Carroll.
Br J Haematol, 2014 Jul 06; 167(1). PMID: 24995804    Free PMC article.
CACN-1/Cactin plays a role in Wnt signaling in C. elegans.
Melissa LaBonty, Cleo Szmygiel, +3 authors, Erin J Cram.
PLoS One, 2014 Jul 08; 9(7). PMID: 24999833    Free PMC article.
Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands.
Pradip De, Jennifer Carlson, Brian Leyland-Jones, Nandini Dey.
Oncotarget, 2014 Jul 13; 5(13). PMID: 25015035    Free PMC article.
The detection of the methylated Wif-1 gene is more accurate than a fecal occult blood test for colorectal cancer screening.
Aurelien Amiot, Hicham Mansour, +7 authors, CRC group of Val De Marne.
PLoS One, 2014 Jul 16; 9(7). PMID: 25025467    Free PMC article.
A graphic method for identification of novel glioma related genes.
Yu-Fei Gao, Yang Shu, +5 authors, Yang Jiang.
Biomed Res Int, 2014 Jul 23; 2014. PMID: 25050377    Free PMC article.
Addiction to multiple oncogenes can be exploited to prevent the emergence of therapeutic resistance.
Peter S Choi, Yulin Li, Dean W Felsher.
Proc Natl Acad Sci U S A, 2014 Jul 30; 111(32). PMID: 25071175    Free PMC article.
Klotho: a novel biomarker for cancer.
Xiangxiang Zhou, Xin Wang.
J Cancer Res Clin Oncol, 2014 Aug 05; 141(6). PMID: 25086986
Wnt pathway activation increases hypoxia tolerance during development.
Merril Gersten, Dan Zhou, +2 authors, Shankar Subramaniam.
PLoS One, 2014 Aug 06; 9(8). PMID: 25093834    Free PMC article.
Activation of β-catenin signalling by TFF1 loss promotes cell proliferation and gastric tumorigenesis.
Mohammed Soutto, DunFa Peng, +6 authors, Wael El-Rifai.
Gut, 2014 Aug 12; 64(7). PMID: 25107557    Free PMC article.
The crucial role of Atg5 in cortical neurogenesis during early brain development.
Xiaohui Lv, Huihui Jiang, +4 authors, Jianwei Jiao.
Sci Rep, 2014 Aug 12; 4. PMID: 25109817    Free PMC article.
Serum Dickkopf-1 expression level positively correlates with a poor prognosis in breast cancer.
Shao-jie Zhou, Shou-rong Zhuo, +2 authors, Zi-liang Wang.
Diagn Pathol, 2014 Aug 15; 9. PMID: 25116444    Free PMC article.
Genetic analysis of colon tumors induced by a dietary carcinogen PhIP in CYP1A humanized mice: Identification of mutation of β-catenin/Ctnnb1 as the driver gene for the carcinogenesis.
Hong Wang, Hong Zhou, +2 authors, Chung S Yang.
Mol Carcinog, 2014 Aug 19; 54(11). PMID: 25131582    Free PMC article.
WNT7A/β-catenin signaling induces FGF1 and influences sensitivity to niclosamide in ovarian cancer.
M L King, M E Lindberg, +7 authors, K Hayashi.
Oncogene, 2014 Sep 02; 34(26). PMID: 25174399    Free PMC article.
MicroRNAs in liver cancer: a model for investigating pathogenesis and novel therapeutic approaches.
E Callegari, L Gramantieri, +3 authors, M Negrini.
Cell Death Differ, 2014 Sep 06; 22(1). PMID: 25190143    Free PMC article.
Highly Cited. Review.
Wnt activation affects proliferation, invasiveness and radiosensitivity in medulloblastoma.
Roberta Salaroli, Alice Ronchi, +7 authors, Giovanna Cenacchi.
J Neurooncol, 2014 Sep 30; 121(1). PMID: 25261924
Genomically driven precision medicine to improve outcomes in anaplastic thyroid cancer.
Nicole Pinto, Morgan Black, +4 authors, Anthony C Nichols.
J Oncol, 2014 Oct 03; 2014. PMID: 25276134    Free PMC article.
Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy.
Estefania Martino-Echarri, Beric R Henderson, Mariana G Brocardo.
Oncotarget, 2014 Oct 11; 5(20). PMID: 25301724    Free PMC article.
The Role of Glycogen Synthase Kinase 3 Beta in Neuroinflammation and Pain.
Dylan Warren Maixner, Han-Rong Weng.
J Pharm Pharmacol (Los Angel), 2013 Jan 01; 1(1). PMID: 25309941    Free PMC article.
A novel aminothiazole KY-05009 with potential to inhibit Traf2- and Nck-interacting kinase (TNIK) attenuates TGF-β1-mediated epithelial-to-mesenchymal transition in human lung adenocarcinoma A549 cells.
Jiyeon Kim, Seong-Hee Moon, +3 authors, Seong Hwan Kim.
PLoS One, 2014 Oct 23; 9(10). PMID: 25337707    Free PMC article.
Interactions of human MSC with head and neck squamous cell carcinoma cell line PCI-13 reduce markers of epithelia-mesenchymal transition.
F Böhrnsen, M Fricke, +3 authors, F J Kramer.
Clin Oral Investig, 2014 Oct 28; 19(5). PMID: 25346374
β-CateninC429S mice exhibit sterility consequent to spatiotemporally sustained Wnt signalling in the internal genitalia.
Takuya Murata, Yuichi Ishitsuka, +9 authors, Yoichi Gondo.
Sci Rep, 2014 Nov 08; 4. PMID: 25376241    Free PMC article.
p, p'-Dichlorodiphenyldichloroethylene induces colorectal adenocarcinoma cell proliferation through oxidative stress.
Li Song, Jianxin Liu, +3 authors, Weiping Liu.
PLoS One, 2014 Nov 12; 9(11). PMID: 25386960    Free PMC article.
Molecular and genetic aspects of odontogenic lesions.
Elizabeth A Bilodeau, Joanne L Prasad, Faizan Alawi, Raja R Seethala.
Head Neck Pathol, 2014 Nov 21; 8(4). PMID: 25409852    Free PMC article.
Combined use of vitamin D3 and metformin exhibits synergistic chemopreventive effects on colorectal neoplasia in rats and mice.
Wan Li, Qi-Long Wang, +9 authors, Yong-Jie Wu.
Cancer Prev Res (Phila), 2014 Nov 25; 8(2). PMID: 25416412    Free PMC article.
Wnt signaling is involved in 6-benzylthioinosine-induced AML cell differentiation.
Shaolei Zang, Na Liu, +6 authors, William Tse.
BMC Cancer, 2014 Nov 28; 14. PMID: 25428027    Free PMC article.
MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer.
Wei-Yu Chen, Shih-Yang Liu, +6 authors, Yen-Nien Liu.
Oncotarget, 2014 Dec 02; 6(1). PMID: 25436980    Free PMC article.
Targeting serum glucocorticoid-regulated kinase-1 in squamous cell carcinoma of the head and neck: a novel modality of local control.
Henrik O Berdel, Hongyu Yin, +8 authors, Babak Baban.
PLoS One, 2014 Dec 09; 9(12). PMID: 25485633    Free PMC article.
Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages.
Monica Nagendran, Prateek Arora, +4 authors, Mahendra Sonawane.
Development, 2014 Dec 19; 142(2). PMID: 25519245    Free PMC article.
Immunohistochemical demonstration of alteration of β-catenin during tumor metastasis by different mechanisms according to histology in lung cancer.
Xianhua Xu, Ji Eun Kim, +4 authors, Jin-Haeng Chung.
Exp Ther Med, 2015 Jan 13; 9(2). PMID: 25574191    Free PMC article.
Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage.
Si Tao, Duozhuang Tang, +8 authors, Karl Lenhard Rudolph.
EMBO J, 2015 Jan 23; 34(5). PMID: 25609789    Free PMC article.
Comparison of human cell signaling pathway databases--evolution, drawbacks and challenges.
Saikat Chowdhury, Ram Rup Sarkar.
Database (Oxford), 2015 Jan 30; 2015. PMID: 25632107    Free PMC article.
SMK-17, a MEK1/2-specific inhibitor, selectively induces apoptosis in β-catenin-mutated tumors.
Masaki Kiga, Ayako Nakayama, +5 authors, Masaya Imoto.
Sci Rep, 2015 Feb 03; 5. PMID: 25640451    Free PMC article.
Anti-inflammatory activity of Wnt signaling in enteric nervous system: in vitro preliminary evidences in rat primary cultures.
Rosa Di Liddo, Thomas Bertalot, +5 authors, Karl Herbert Schäfer.
J Neuroinflammation, 2015 Feb 04; 12. PMID: 25644719    Free PMC article.
HSP105 recruits protein phosphatase 2A to dephosphorylate β-catenin.
Nancy Yu, Michael Kakunda, +6 authors, XiaoDong Huang.
Mol Cell Biol, 2015 Feb 04; 35(8). PMID: 25645927    Free PMC article.
Clinical significance of aberrant Wnt7a promoter methylation in human non-small cell lung cancer in Koreans.
Tae-Hyung Kim, Ji-Yong Moon, +5 authors, Jang Won Sohn.
J Korean Med Sci, 2015 Feb 06; 30(2). PMID: 25653486    Free PMC article.
Rapid changes in gene expression direct rapid shifts in intestinal form and function in the Burmese python after feeding.
Audra L Andrew, Daren C Card, +5 authors, Todd A Castoe.
Physiol Genomics, 2015 Feb 12; 47(5). PMID: 25670730    Free PMC article.
PPARγ suppressed Wnt/β-catenin signaling pathway and its downstream effector SOX9 expression in gastric cancer cells.
Xiyun Ren, Dongyou Zheng, +4 authors, Wenjing Tian.
Med Oncol, 2015 Feb 28; 32(4). PMID: 25720524
Wnt7a is a novel inducer of β-catenin-independent tumor-suppressive cellular senescence in lung cancer.
R K Bikkavilli, S Avasarala, +12 authors, R A Winn.
Oncogene, 2015 Mar 03; 34(42). PMID: 25728679    Free PMC article.
Parameter-free methods distinguish Wnt pathway models and guide design of experiments.
Adam L MacLean, Zvi Rosen, Helen M Byrne, Heather A Harrington.
Proc Natl Acad Sci U S A, 2015 Mar 03; 112(9). PMID: 25730853    Free PMC article.
Nuclear signaling from cadherin adhesion complexes.
Pierre D McCrea, Meghan T Maher, Cara J Gottardi.
Curr Top Dev Biol, 2015 Mar 04; 112. PMID: 25733140    Free PMC article.
Notch signaling in the prostate: critical roles during development and in the hallmarks of prostate cancer biology.
Gang Deng, Libin Ma, +4 authors, Zhijian Yu.
J Cancer Res Clin Oncol, 2015 Mar 05; 142(3). PMID: 25736982
From the Biology of PP2A to the PADs for Therapy of Hematologic Malignancies.
Maria Ciccone, George A Calin, Danilo Perrotti.
Front Oncol, 2015 Mar 13; 5. PMID: 25763353    Free PMC article.
Cell surface markers of cancer stem cells: diagnostic macromolecules and targets for drug delivery.
Timothy E Andrews, Dan Wang, Daniel A Harki.
Drug Deliv Transl Res, 2013 Apr 01; 3(2). PMID: 25787981
Downregulation of miR-432 activates Wnt/β-catenin signaling and promotes human hepatocellular carcinoma proliferation.
Nan Jiang, Wen-Jie Chen, +5 authors, Guo-Ying Wang.
Oncotarget, 2015 Mar 24; 6(10). PMID: 25797263    Free PMC article.
Effects of fulvestrant on biological activity and Wnt expression in rat GH3 cells.
Jiwei Bai, Yan Wang, Chuzhong Li, Yazhuo Zhang.
Neural Regen Res, 2012 Feb 05; 7(4). PMID: 25806070    Free PMC article.
Phospholipid remodeling and eicosanoid signaling in colon cancer cells.
Siddhartha Das, Leobarda Robles Martinez, Suparna Ray.
Indian J Biochem Biophys, 2015 Apr 01; 51(6). PMID: 25823224    Free PMC article.
miR-942 promotes cancer stem cell-like traits in esophageal squamous cell carcinoma through activation of Wnt/β-catenin signalling pathway.
Chunlei Ge, Shikai Wu, +13 authors, Xin Song.
Oncotarget, 2015 Apr 07; 6(13). PMID: 25844602    Free PMC article.
Transcriptome analysis of Wnt3a-treated triple-negative breast cancer cells.
Sylvie Maubant, Bruno Tesson, +7 authors, Thierry Dubois.
PLoS One, 2015 Apr 08; 10(4). PMID: 25848952    Free PMC article.
A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/β-catenin signaling pathway.
Arabinda Das, Rickey Miller, +9 authors, Sunil J Patel.
Tumour Biol, 2015 Apr 13; 36(9). PMID: 25864108
Inhibition of β-catenin signaling suppresses pancreatic tumor growth by disrupting nuclear β-catenin/TCF-1 complex: critical role of STAT-3.
Kartick C Pramanik, Neel M Fofaria, +3 authors, Sanjay K Srivastava.
Oncotarget, 2015 Apr 15; 6(13). PMID: 25869100    Free PMC article.
Pygo2 siRNA Inhibit the Growth and Increase Apoptosis of U251 Cell by Suppressing Histone H3K4 Trimethylation.
Mingcong Li, Linlin Chao, +6 authors, Zhanxiang Wang.
J Mol Neurosci, 2015 Apr 15; 56(4). PMID: 25869613
Effects of Weipixiao (胃痞消) on Wnt pathway-associated proteins in gastric mucosal epithelial cells from rats with gastric precancerous lesions.
Jin-hao Zeng, Hua-feng Pan, +7 authors, Yan Yan.
Chin J Integr Med, 2015 Apr 17; 22(4). PMID: 25877463
Dietary compound isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation.
Neng Wang, Zhiyu Wang, +8 authors, Jianping Chen.
Oncotarget, 2015 Apr 29; 6(12). PMID: 25918249    Free PMC article.
Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial.
Sushma S Thomas, Karen W Makar, +10 authors, John D Potter.
BMC Med Genet, 2015 May 01; 16. PMID: 25927723    Free PMC article.
Identification of therapeutic targets for glioblastoma by network analysis.
D Friedmann-Morvinski, V Bhargava, +2 authors, S Subramaniam.
Oncogene, 2015 May 12; 35(5). PMID: 25961929    Free PMC article.
Overexpression of chromosome 14 open reading frame 166 correlates with disease progression and poorer prognosis in human NPC.
Lin Yang, Fengyan Li, +4 authors, Yong Chen.
Tumour Biol, 2015 May 13; 36(10). PMID: 25964093
Relationship between osteopontin and β-catenin immunohistochemical expression and prognostic parameters of colorectal carcinoma.
Nermeen S Youssef, Wesam M Osman.
Int J Clin Exp Pathol, 2015 May 15; 8(2). PMID: 25973035    Free PMC article.
Loss of TFF1 promotes Helicobacter pylori-induced β-catenin activation and gastric tumorigenesis.
Mohammed Soutto, Judith Romero-Gallo, +5 authors, Wael El-Rifai.
Oncotarget, 2015 May 20; 6(20). PMID: 25980439    Free PMC article.
Aberrant activation of Wnt/β-catenin signaling drives proliferation of bone sarcoma cells.
Changbao Chen, Meng Zhao, +3 authors, Xinlong Ma.
Oncotarget, 2015 May 23; 6(19). PMID: 25999350    Free PMC article.
Chemoprevention in gastrointestinal physiology and disease. Anti-inflammatory approaches for colorectal cancer chemoprevention.
Alexandra M Fajardo, Gary A Piazza.
Am J Physiol Gastrointest Liver Physiol, 2015 May 30; 309(2). PMID: 26021807    Free PMC article.
An aberrant nuclear localization of E-cadherin is a potent inhibitor of Wnt/β-catenin-elicited promotion of the cancer stem cell phenotype.
Y-J Su, Y-W Chang, +2 authors, J-L Lee.
Oncogenesis, 2015 Jun 16; 4. PMID: 26075748    Free PMC article.
Cancer microenvironment, inflammation and cancer stem cells: A hypothesis for a paradigm change and new targets in cancer control.
Russell L Blaylock.
Surg Neurol Int, 2015 Jun 23; 6. PMID: 26097771    Free PMC article.
The role of WNT signaling in adult ovarian folliculogenesis.
J A Hernandez Gifford.
Reproduction, 2015 Jul 02; 150(4). PMID: 26130815    Free PMC article.
Antiproliferative effect of the methanol extract from the roots of Petasites japonicus on Hep3B hepatocellular carcinoma cells in vitro and in vivo.
Hyun Jung Kim, Song Yi Park, +2 authors, Young-Min Kim.
Exp Ther Med, 2015 Jul 03; 9(5). PMID: 26136894    Free PMC article.
Genetics, diagnosis and management of colorectal cancer (Review).
Marina De Rosa, Ugo Pace, +4 authors, Paolo Delrio.
Oncol Rep, 2015 Jul 08; 34(3). PMID: 26151224    Free PMC article.
Highly Cited. Review.
Structure-activity relationship studies of QS11, a small molecule Wnt synergistic agonist.
Manish K Singh, Huanyao Gao, +4 authors, Qisheng Zhang.
Bioorg Med Chem Lett, 2015 Jul 15; 25(21). PMID: 26152429    Free PMC article.
Deubiquitinase USP47/UBP64E Regulates β-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling.
Jiandang Shi, Yajuan Liu, +4 authors, Chunming Liu.
Mol Cell Biol, 2015 Jul 15; 35(19). PMID: 26169834    Free PMC article.
Expression of hepaCAM inhibits bladder cancer cell proliferation via a Wnt/β-catenin-dependent pathway in vitro and in vivo.
Hong-Fei Du, Li-Ping Ou, +5 authors, Chun-Li Luo.
Cancer Biol Ther, 2015 Jul 21; 16(10). PMID: 26192362    Free PMC article.
Role of DNA methylation in renal cell carcinoma.
Niraj Shenoy, Nishanth Vallumsetla, +5 authors, Amit Verma.
J Hematol Oncol, 2015 Jul 23; 8. PMID: 26198328    Free PMC article.
Krüppel-like factor 9 (KLF9) prevents colorectal cancer through inhibition of interferon-related signaling.
Adam R Brown, Rosalia C M Simmen, +3 authors, Frank A Simmen.
Carcinogenesis, 2015 Jul 27; 36(9). PMID: 26210742    Free PMC article.
Wnt/β-Catenin-Responsive Cells in Prostatic Development and Regeneration.
Suk Hyung Lee, Daniel T Johnson, +4 authors, Zijie Sun.
Stem Cells, 2015 Jul 30; 33(11). PMID: 26220362    Free PMC article.
Molecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis.
Satya Narayan, Ritika Sharma.
Life Sci, 2015 Sep 04; 139. PMID: 26334567    Free PMC article.
WNT10B enhances proliferation through β-catenin and RAC1 GTPase in human corneal endothelial cells.
Jeong Goo Lee, Martin Heur.
J Biol Chem, 2015 Sep 16; 290(44). PMID: 26370090    Free PMC article.
The double trouble of metabolic diseases: the diabetes-cancer link.
Slavica Tudzarova, Mahasin A Osman.
Mol Biol Cell, 2015 Sep 16; 26(18). PMID: 26371080    Free PMC article.
Secreted frizzled-related protein promotors are hypermethylated in cutaneous squamous carcinoma compared with normal epidermis.
Junqin Liang, Xiaojing Kang, +9 authors, Xiongming Pu.
BMC Cancer, 2015 Sep 24; 15. PMID: 26394929    Free PMC article.
Resveratrol inhibits canonical Wnt signaling in human MG-63 osteosarcoma cells.
Yonggen Zou, Jiexiang Yang, Dianming Jiang.
Mol Med Rep, 2015 Sep 24; 12(5). PMID: 26398440    Free PMC article.
A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations.
Michael Buchert, Franziska Rohde, +12 authors, Klaus-Peter Janssen.
Dis Model Mech, 2015 Sep 24; 8(11). PMID: 26398937    Free PMC article.
Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis.
Anja Konzack, Mirza Jakupovic, +5 authors, Thomas Kietzmann.
Antioxid Redox Signal, 2015 Oct 01; 23(14). PMID: 26422659    Free PMC article.
JRK is a positive regulator of β-catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancer.
L Pangon, I Ng, +13 authors, M R J Kohonen-Corish.
Oncogene, 2015 Oct 13; 35(22). PMID: 26455321
Ideal sphere-forming culture conditions to maintain pluripotency in a hepatocellular carcinoma cell lines.
Seon Ok Min, Sang Woo Lee, Seon Young Bak, Kyung Sik Kim.
Cancer Cell Int, 2015 Oct 13; 15. PMID: 26457068    Free PMC article.
A novel prediction model for human papillomavirus-associated oropharyngeal squamous cell carcinoma using p16 and subcellular β-catenin expression.
Guoqing Qian, Zhongliang Hu, +9 authors, Zhuo Georgia Chen.
J Oral Pathol Med, 2015 Oct 24; 45(6). PMID: 26493274    Free PMC article.
EMDomics: a robust and powerful method for the identification of genes differentially expressed between heterogeneous classes.
Sheida Nabavi, Daniel Schmolze, +2 authors, Andrew H Beck.
Bioinformatics, 2015 Oct 31; 32(4). PMID: 26515818    Free PMC article.
GalNAc-T14 promotes metastasis through Wnt dependent HOXB9 expression in lung adenocarcinoma.
Ok-Seon Kwon, Ensel Oh, +8 authors, Hyuk-Jin Cha.
Oncotarget, 2015 Nov 07; 6(39). PMID: 26544896    Free PMC article.
A Cytosolic Multiprotein Complex Containing p85α Is Required for β-Catenin Activation in Colitis and Colitis-associated Cancer.
Tatiana Goretsky, Emily M Bradford, +5 authors, Terrence A Barrett.
J Biol Chem, 2015 Nov 14; 291(8). PMID: 26565021    Free PMC article.
Identification of CTNNB1 mutations, CTNNB1 amplifications, and an Axin2 splice variant in juvenile angiofibromas.
Silke Wemmert, Vivienne Willnecker, +5 authors, Bernhard Schick.
Tumour Biol, 2015 Nov 18; 37(4). PMID: 26572152
Wnt-/-β-catenin pathway signaling in human hepatocellular carcinoma.
Jaques Waisberg, Gabriela Tognini Saba.
World J Hepatol, 2015 Nov 27; 7(26). PMID: 26609340    Free PMC article.
Low expression of N-myc downstream-regulated gene 2 (NDRG2) correlates with poor prognosis in hepatoblastoma.
Jan Gödeke, Elke Luxenburger, +5 authors, Roland Kappler.
Hepatol Int, 2015 Dec 10; 10(2). PMID: 26646663
Nuclear phosphorylated Y142 β-catenin accumulates in astrocytomas and glioblastomas and regulates cell invasion.
Mireia Náger, Maria Santacana, +5 authors, Judit Herreros.
Cell Cycle, 2015 Dec 15; 14(22). PMID: 26654598    Free PMC article.
WNT5a is required for normal ovarian follicle development and antagonizes gonadotropin responsiveness in granulosa cells by suppressing canonical WNT signaling.
Atefeh Abedini, Gustavo Zamberlam, +8 authors, Derek Boerboom.
FASEB J, 2015 Dec 17; 30(4). PMID: 26667040    Free PMC article.
Mesenchymal Stem Cell-Mediated Effects of Tumor Support or Suppression.
Ki-Jong Rhee, Jong In Lee, Young Woo Eom.
Int J Mol Sci, 2015 Dec 24; 16(12). PMID: 26694366    Free PMC article.
Highly Cited. Review.
Association of Wnt signaling pathway genetic variants in gallbladder cancer susceptibility and survival.
Anu Yadav, Annapurna Gupta, +6 authors, Balraj Mittal.
Tumour Biol, 2015 Dec 31; 37(6). PMID: 26715268
Human Cytomegalovirus Inhibits the PARsylation Activity of Tankyrase--A Potential Strategy for Suppression of the Wnt Pathway.
Sujayita Roy, Fengjie Liu, Ravit Arav-Boger.
Viruses, 2016 Jan 06; 8(1). PMID: 26729153    Free PMC article.
Molecular pathogenesis of sporadic colorectal cancers.
Hidetsugu Yamagishi, Hajime Kuroda, Yasuo Imai, Hideyuki Hiraishi.
Chin J Cancer, 2016 Jan 08; 35. PMID: 26738600    Free PMC article.
Activating mutations in CTNNB1 in aldosterone producing adenomas.
Tobias Åkerström, Rajani Maharjan, +13 authors, Peyman Björklund.
Sci Rep, 2016 Jan 28; 6. PMID: 26815163    Free PMC article.
Highly Cited.
GSK-3β Governs Inflammation-Induced NFATc2 Signaling Hubs to Promote Pancreatic Cancer Progression.
Sandra Baumgart, Nai-Ming Chen, +14 authors, Albrecht Neesse.
Mol Cancer Ther, 2016 Jan 30; 15(3). PMID: 26823495    Free PMC article.
PAF-Wnt signaling-induced cell plasticity is required for maintenance of breast cancer cell stemness.
Xin Wang, Youn-Sang Jung, +9 authors, Jae-Il Park.
Nat Commun, 2016 Feb 05; 7. PMID: 26843124    Free PMC article.
Downregulation of Pygopus 2 inhibits vascular mimicry in glioma U251 cells by suppressing the canonical Wnt signaling pathway.
Haidong Wang, Jianhua Fu, +4 authors, Yongsheng Xiang.
Oncol Lett, 2016 Feb 13; 11(1). PMID: 26870266    Free PMC article.
High Expression of miR-532-5p, a Tumor Suppressor, Leads to Better Prognosis in Ovarian Cancer Both In Vivo and In Vitro.
Fan Wang, Jeremy T-H Chang, Chester Jingshiu Kao, R Stephanie Huang.
Mol Cancer Ther, 2016 Feb 14; 15(5). PMID: 26873729    Free PMC article.
Pygo2 activates MDR1 expression and mediates chemoresistance in breast cancer via the Wnt/β-catenin pathway.
Z-M Zhang, J-F Wu, +5 authors, B-A Li.
Oncogene, 2016 Feb 16; 35(36). PMID: 26876203
Discovery of candidate tumor biomarkers for treatment with intraperitoneal chemotherapy for ovarian cancer.
Brandon-Luke L Seagle, Kevin H Eng, +5 authors, Shohreh Shahabi.
Sci Rep, 2016 Feb 18; 6. PMID: 26883286    Free PMC article.
The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma.
Luisa Cironi, Tanja Petricevic, +7 authors, Ivan Stamenkovic.
Sci Rep, 2016 Feb 26; 6. PMID: 26905812    Free PMC article.
Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling.
Meiying Zhang, Enqiang Linghu, +6 authors, Mingzhou Guo.
Oncotarget, 2016 Feb 27; 7(14). PMID: 26919254    Free PMC article.
Small molecule inhibitors of the Dishevelled-CXXC5 interaction are new drug candidates for bone anabolic osteoporosis therapy.
Hyun-Yi Kim, Sehee Choi, +8 authors, Kang-Yell Choi.
EMBO Mol Med, 2016 Mar 05; 8(4). PMID: 26941261    Free PMC article.
Genetic Variants in the Wnt Signaling Pathway Are Not Associated with Survival Outcome of Non-Small Cell Lung Cancer in a Korean Population.
Seung Soo Yoo, Mi Jeong Hong, +10 authors, Jae Yong Park.
J Korean Med Sci, 2016 Mar 10; 31(3). PMID: 26955250    Free PMC article.
Unfolding the Role of Large Heat Shock Proteins: New Insights and Therapeutic Implications.
Daming Zuo, John Subjeck, Xiang-Yang Wang.
Front Immunol, 2016 Mar 15; 7. PMID: 26973652    Free PMC article.
CYP1B1 Enhances Cell Proliferation and Metastasis through Induction of EMT and Activation of Wnt/β-Catenin Signaling via Sp1 Upregulation.
Yeo-Jung Kwon, Hyoung-Seok Baek, +3 authors, Young-Jin Chun.
PLoS One, 2016 Mar 18; 11(3). PMID: 26981862    Free PMC article.
The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation.
Tsung-Chieh Lin, Chia-Yi Su, +15 authors, Michael Hsiao.
Elife, 2016 Mar 18; 5. PMID: 26984280    Free PMC article.
MicroRNA-1229 overexpression promotes cell proliferation and tumorigenicity and activates Wnt/β-catenin signaling in breast cancer.
Zhanyao Tan, Haiqing Zheng, +8 authors, Jun Li.
Oncotarget, 2016 Mar 19; 7(17). PMID: 26992223    Free PMC article.
Expression patterns of Wnt signaling component, secreted frizzled‑related protein 3 in astrocytoma and glioblastoma.
Nives Pećina-Šlaus, Anja Kafka, +4 authors, Goran Mrak.
Mol Med Rep, 2016 Apr 02; 13(5). PMID: 27035837    Free PMC article.
T cell factor-4 functions as a co-activator to promote NF-κB-dependent MMP-15 expression in lung carcinoma cells.
Yuliang Liu, Yu Xu, Shuliang Guo, Hong Chen.
Sci Rep, 2016 Apr 06; 6. PMID: 27046058    Free PMC article.
Wnt9A Induction Linked to Suppression of Human Colorectal Cancer Cell Proliferation.
Irshad Ali, Bani Medegan, Donald P Braun.
Int J Mol Sci, 2016 Apr 07; 17(4). PMID: 27049382    Free PMC article.
α-Actinin-4 induces the epithelial-to-mesenchymal transition and tumorigenesis via regulation of Snail expression and β-catenin stabilization in cervical cancer.
H-T An, S Yoo, J Ko.
Oncogene, 2016 Apr 12; 35(45). PMID: 27065319
Multifaceted enrichment analysis of RNA-RNA crosstalk reveals cooperating micro-societies in human colorectal cancer.
Tommaso Mazza, Gianluigi Mazzoccoli, +11 authors, Ada Piepoli.
Nucleic Acids Res, 2016 Apr 14; 44(9). PMID: 27067546    Free PMC article.
Changes in mitotic reorientation and Wnt/AR signaling in rat prostate epithelial cells exposed to subchronic testosterone.
Xiangyun Liu, Y I Cheng, +7 authors, Zuyue Sun.
Exp Ther Med, 2016 Apr 14; 11(4). PMID: 27073450    Free PMC article.
Crosstalk of the Wnt/β-catenin pathway with other pathways in cancer cells.
Saint-Aaron L Morris, Suyun Huang.
Genes Dis, 2016 Apr 16; 3(1). PMID: 27081668    Free PMC article.
Interaction between APC and Fen1 during breast carcinogenesis.
Satya Narayan, Aruna S Jaiswal, +3 authors, Robert A Hromas.
DNA Repair (Amst), 2016 Apr 19; 41. PMID: 27088617    Free PMC article.
Fibersol-2 induces apoptosis of Apc-deficient colorectal Cancer (SW480) cells and decreases polyp formation in Apc MIN mice.
Sara Cuesta Sancho, Susan Losee Olson, +3 authors, Fabian Preuss.
Cancer Biol Ther, 2016 May 05; 17(6). PMID: 27143108    Free PMC article.
C-terminus of MUC16 activates Wnt signaling pathway through its interaction with β-catenin to promote tumorigenesis and metastasis.
Qi Liu, Zhen Cheng, +9 authors, Xiaotong Li.
Oncotarget, 2016 May 12; 7(24). PMID: 27167110    Free PMC article.
Homeobox protein VentX induces p53-independent apoptosis in cancer cells.
Hong Gao, Bin Wu, Yi Le, Zhenglun Zhu.
Oncotarget, 2016 Oct 26; 7(26). PMID: 27175592    Free PMC article.
The life and works of S100P - from conception to cancer.
Filip Prica, Tomasz Radon, Yuzhu Cheng, Tatjana Crnogorac-Jurcevic.
Am J Cancer Res, 2016 May 18; 6(2). PMID: 27186425    Free PMC article.
Computational Framework for Prediction of Peptide Sequences That May Mediate Multiple Protein Interactions in Cancer-Associated Hub Proteins.
Debasree Sarkar, Piya Patra, Abhirupa Ghosh, Sudipto Saha.
PLoS One, 2016 May 25; 11(5). PMID: 27218803    Free PMC article.
JMJD2B is required for Helicobacter pylori-induced gastric carcinogenesis via regulating COX-2 expression.
Fengjuan Han, Juchao Ren, +6 authors, Wenjuan Li.
Oncotarget, 2016 Oct 23; 7(25). PMID: 27232941    Free PMC article.
Molecular and phenotypic responses of Japanese medaka (Oryzias latipes) early life stages to environmental concentrations of cadmium in sediment.
Iris Barjhoux, Patrice Gonzalez, Magalie Baudrimont, Jérôme Cachot.
Environ Sci Pollut Res Int, 2016 Jun 04; 23(18). PMID: 27255318
Emerging roles and underlying molecular mechanisms of DNAJB6 in cancer.
Erhong Meng, Lalita A Shevde, Rajeev S Samant.
Oncotarget, 2016 Jun 09; 7(33). PMID: 27276715    Free PMC article.
Characterization of Somatically-Eliminated Genes During Development of the Sea Lamprey (Petromyzon marinus).
Stephanie A Bryant, Joseph R Herdy, Chris T Amemiya, Jeramiah J Smith.
Mol Biol Evol, 2016 Jun 12; 33(9). PMID: 27288344    Free PMC article.
Regulation of intestinal homeostasis and tumorigenesis by the transcriptional coregulator RIP140.
Vincent Cavaillès, Marion Lapierre.
Mol Cell Oncol, 2014 Apr 01; 1(2). PMID: 27308333    Free PMC article.
CKAP4 is identified as a receptor for Dickkopf in cancer cells.
Dheeraj Bhavanasi, Kelsey F Speer, Peter S Klein.
J Clin Invest, 2016 Jun 21; 126(7). PMID: 27322056    Free PMC article.
The anti-apoptotic PON2 protein is Wnt/β-catenin-regulated and correlates with radiotherapy resistance in OSCC patients.
Maximilian Krüger, Julianna Amort, +7 authors, Sven Horke.
Oncotarget, 2016 Jun 21; 7(32). PMID: 27322774    Free PMC article.
Dual role of GRK5 in cancer development and progression.
J Gambardella, A Franco, +6 authors, D Sorriento.
Transl Med UniSa, 2016 Jun 22; 14. PMID: 27326393    Free PMC article.
Metacycloprodigiosin induced cell death selectively in β-catenin-mutated tumor cells.
Hiroaki Ikeda, Yuki Shikata, +2 authors, Masaya Imoto.
J Antibiot (Tokyo), 2016 Jun 23; 70(1). PMID: 27328865
Carboxypeptidase E (CPE) inhibits the secretion and activity of Wnt3a.
N Skalka, M Caspi, +3 authors, R Rosin-Arbesfeld.
Oncogene, 2016 Jul 05; 35(50). PMID: 27375026
Export of microRNAs: A Bridge between Breast Carcinoma and Their Neighboring Cells.
Devashree Jahagirdar, Shruti Purohit, Aayushi Jain, Nilesh Kumar Sharma.
Front Oncol, 2016 Jul 06; 6. PMID: 27379209    Free PMC article.
Wnt Lipidation and Modifiers in Intestinal Carcinogenesis and Cancer.
Elke Kaemmerer, Nikolaus Gassler.
Cancers (Basel), 2016 Jul 22; 8(7). PMID: 27438855    Free PMC article.
Wnt signalling is a bi-directional vulnerability of cancer cells.
David J Duffy, Aleksandar Krstic, +13 authors, Walter Kolch.
Oncotarget, 2016 Aug 18; 7(37). PMID: 27531891    Free PMC article.
TNIK inhibition abrogates colorectal cancer stemness.
Mari Masuda, Yuko Uno, +11 authors, Tesshi Yamada.
Nat Commun, 2016 Aug 27; 7. PMID: 27562646    Free PMC article.
Promising Druggable Target in Head and Neck Squamous Cell Carcinoma: Wnt Signaling.
Amnani Aminuddin, Pei Yuen Ng.
Front Pharmacol, 2016 Aug 30; 7. PMID: 27570510    Free PMC article.
Apoptotic pathways as a therapeutic target for colorectal cancer treatment.
Aman M Abraha, Ezra B Ketema.
World J Gastrointest Oncol, 2016 Aug 31; 8(8). PMID: 27574550    Free PMC article.
Defective CFTR- β-catenin interaction promotes NF-κB nuclear translocation and intestinal inflammation in cystic fibrosis.
Kaisheng Liu, Xiaohu Zhang, +3 authors, Hsiao Chang Chan.
Oncotarget, 2016 Sep 03; 7(39). PMID: 27588407    Free PMC article.
The Robustness of Pathway Analysis in Identifying Potential Drug Targets in Non-Small Cell Lung Carcinoma.
Andrew Dalby, Ian Bailey.
Microarrays (Basel), 2014 Jan 01; 3(4). PMID: 27600345    Free PMC article.
Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines.
Chao Yang, Qian Zhou, +10 authors, Chunling Wan.
Sci Rep, 2016 Sep 10; 6. PMID: 27609465    Free PMC article.
Epigenetic loss of putative tumor suppressor SFRP3 correlates with poor prognosis of lung adenocarcinoma patients.
Martin Schlensog, Lara Magnus, +9 authors, Edgar Dahl.
Epigenetics, 2016 Sep 15; 13(3). PMID: 27623992    Free PMC article.
Prolonged inflammatory microenvironment is crucial for pro-neoplastic growth and genome instability: a detailed review.
Kumari Anuja, Souvick Roy, +3 authors, Birendranath Banerjee.
Inflamm Res, 2016 Sep 23; 66(2). PMID: 27653961
90K Glycoprotein Promotes Degradation of Mutant β-Catenin Lacking the ISGylation or Phosphorylation Sites in the N-terminus.
So-Yeon Park, Somy Yoon, Hangun Kim, Kyung Keun Kim.
Neoplasia, 2016 Sep 27; 18(10). PMID: 27668402    Free PMC article.
Lactobacilli Differentially Modulate mTOR and Wnt/ β-Catenin Pathways in Different Cancer Cell Lines.
Zahra Taherian-Esfahani, Atieh Abedin-Do, +3 authors, Elahe Motevaseli.
Iran J Cancer Prev, 2016 Oct 06; 9(3). PMID: 27703648    Free PMC article.
Transcription Factor ZBP-89 Drives a Feedforward Loop of β-Catenin Expression in Colorectal Cancer.
Bryan E Essien, Sinju Sundaresan, +10 authors, Juanita L Merchant.
Cancer Res, 2016 Oct 21; 76(23). PMID: 27758879    Free PMC article.
Attractor landscape analysis of colorectal tumorigenesis and its reversion.
Sung-Hwan Cho, Sang-Min Park, +2 authors, Kwang-Hyun Cho.
BMC Syst Biol, 2016 Oct 22; 10(1). PMID: 27765040    Free PMC article.
Deubiquitinase USP9X deubiquitinates β-catenin and promotes high grade glioma cell growth.
Bo Yang, Shiming Zhang, +5 authors, Conghua Xie.
Oncotarget, 2016 Oct 27; 7(48). PMID: 27783990    Free PMC article.
Mammary gland stem cells and their application in breast cancer.
Xing Yang, Hui Wang, Baowei Jiao.
Oncotarget, 2016 Oct 30; 8(6). PMID: 27793013    Free PMC article.
miR-92a-3p Exerts Various Effects in Glioma and Glioma Stem-Like Cells Specifically Targeting CDH1/β-Catenin and Notch-1/Akt Signaling Pathways.
Hang Song, Yao Zhang, +3 authors, Liudi Yuan.
Int J Mol Sci, 2016 Nov 02; 17(11). PMID: 27801803    Free PMC article.
Nerve growth factor modulates the tumor cells migration in ovarian cancer through the WNT/β-catenin pathway.
Bo Li, Shaoxi Cai, +8 authors, Misha Zou.
Oncotarget, 2016 Nov 12; 7(49). PMID: 27835587    Free PMC article.
STAT3 Potentiates SIAH-1 Mediated Proteasomal Degradation of β-Catenin in Human Embryonic Kidney Cells.
Minkyung Shin, Eun Hee Yi, +6 authors, Sang-Kyu Ye.
Mol Cells, 2016 Nov 23; 39(11). PMID: 27871173    Free PMC article.
Versatile, sensitive liquid chromatography mass spectrometry - Implementation of 10 μm OT columns suitable for small molecules, peptides and proteins.
T Vehus, H Roberg-Larsen, +4 authors, E Lundanes.
Sci Rep, 2016 Nov 30; 6. PMID: 27897190    Free PMC article.
GSK-3β controls NF-kappaB activity via IKKγ/NEMO.
Senad Medunjanin, Lisa Schleithoff, +3 authors, Ruediger C Braun-Dullaeus.
Sci Rep, 2016 Dec 09; 6. PMID: 27929056    Free PMC article.
Multicellular spheroids from normal and neoplastic thyroid tissues as a suitable model to test the effects of multikinase inhibitors.
Valentina Cirello, Valentina Vaira, +8 authors, Laura Fugazzola.
Oncotarget, 2017 Jan 01; 8(6). PMID: 28039458    Free PMC article.
Using knowledge-driven genomic interactions for multi-omics data analysis: metadimensional models for predicting clinical outcomes in ovarian carcinoma.
Dokyoon Kim, Ruowang Li, +3 authors, Marylyn D Ritchie.
J Am Med Inform Assoc, 2017 Jan 04; 24(3). PMID: 28040685    Free PMC article.
Mitochondrial uncoupler exerts a synthetic lethal effect against β-catenin mutant tumor cells.
Yuki Shikata, Masaki Kiga, +5 authors, Masaya Imoto.
Cancer Sci, 2017 Jan 21; 108(4). PMID: 28107588    Free PMC article.
Delayed treatment of 6-Bromoindirubin-3'-oxime stimulates neurogenesis and functional recovery after focal ischemic stroke in mice.
Li-Li Wang, Jimei Li, +2 authors, Shan Ping Yu.
Int J Dev Neurosci, 2017 Jan 24; 57. PMID: 28111255    Free PMC article.
Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma.
Zhiwu Jiang, Xiaofeng Jiang, +17 authors, Peng Li.
Front Immunol, 2017 Jan 27; 7. PMID: 28123387    Free PMC article.
A Tale of Two Signals: AR and WNT in Development and Tumorigenesis of Prostate and Mammary Gland.
Hubert Pakula, Dongxi Xiang, Zhe Li.
Cancers (Basel), 2017 Jan 31; 9(2). PMID: 28134791    Free PMC article.
E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling.
Carmen Dominguez-Brauer, Rahima Khatun, +8 authors, Tak W Mak.
Proc Natl Acad Sci U S A, 2017 Feb 01; 114(7). PMID: 28137882    Free PMC article.
Epigenetics in cancer stem cells.
Tan Boon Toh, Jhin Jieh Lim, Edward Kai-Hua Chow.
Mol Cancer, 2017 Feb 06; 16(1). PMID: 28148257    Free PMC article.
Highly Cited. Review.
CXCL12/CXCR4 axis induced miR-125b promotes invasion and confers 5-fluorouracil resistance through enhancing autophagy in colorectal cancer.
Xinfeng Yu, Wenna Shi, +7 authors, Xianjun Qu.
Sci Rep, 2017 Feb 09; 7. PMID: 28176874    Free PMC article.
Metabolic pattern formation in the tumor microenvironment.
Ziwei Dai, Jason W Locasale.
Mol Syst Biol, 2017 Feb 12; 13(2). PMID: 28183842    Free PMC article.
Revisiting the role of Wnt/β-catenin signaling in prostate cancer.
Jeffrey A Schneider, Susan K Logan.
Mol Cell Endocrinol, 2017 Feb 13; 462(Pt A). PMID: 28189566    Free PMC article.
Inhibition of CCAR1, a Coactivator of β-Catenin, Suppresses the Proliferation and Migration of Gastric Cancer Cells.
Te-Sheng Chang, Kuo-Liang Wei, +5 authors, Ming-Ko Chiang.
Int J Mol Sci, 2017 Feb 24; 18(2). PMID: 28230774    Free PMC article.
CK1 in Developmental Signaling: Hedgehog and Wnt.
Jin Jiang.
Curr Top Dev Biol, 2017 Feb 27; 123. PMID: 28236970    Free PMC article.
In-vitro analysis of selective nutraceuticals binding to human transcription factors through computer aided molecular docking predictions.
Mohammad Teimouri, Muhammad Junaid, +2 authors, Arif Ali.
Bioinformation, 2017 Mar 02; 12(7). PMID: 28246465    Free PMC article.
Understanding the Effectiveness of Natural Compound Mixtures in Cancer through Their Molecular Mode of Action.
Thazin Nwe Aung, Zhipeng Qu, R Daniel Kortschak, David L Adelson.
Int J Mol Sci, 2017 Mar 18; 18(3). PMID: 28304343    Free PMC article.
Nuclear α-catenin mediates the DNA damage response via β-catenin and nuclear actin.
Leonid A Serebryannyy, Alex Yemelyanov, Cara J Gottardi, Primal de Lanerolle.
J Cell Sci, 2017 Mar 30; 130(10). PMID: 28348105    Free PMC article.
A central role for cadherin signaling in cancer.
Antonis Kourtidis, Ruifeng Lu, Lindy J Pence, Panos Z Anastasiadis.
Exp Cell Res, 2017 Apr 17; 358(1). PMID: 28412244    Free PMC article.
Highly Cited. Review.
Melatonin Inhibits Neural Cell Apoptosis and Promotes Locomotor Recovery via Activation of the Wnt/β-Catenin Signaling Pathway After Spinal Cord Injury.
Zhaoliang Shen, Zipeng Zhou, +4 authors, Xiaoqian Dang.
Neurochem Res, 2017 Apr 19; 42(8). PMID: 28417262
Delineating the Common Biological Pathways Perturbed by ASD's Genetic Etiology: Lessons from Network-Based Studies.
Oded Oron, Evan Elliott.
Int J Mol Sci, 2017 Apr 20; 18(4). PMID: 28420080    Free PMC article.
The potential roles of aquaporin 4 in malignant gliomas.
Yu-Long Lan, Xun Wang, +2 authors, Bo Zhang.
Oncotarget, 2017 Apr 21; 8(19). PMID: 28423683    Free PMC article.
Wnt Signaling in Normal and Malignant Stem Cells.
Dheeraj Bhavanasi, Peter S Klein.
Curr Stem Cell Rep, 2017 May 16; 2(4). PMID: 28503404    Free PMC article.
Dalbinol, a rotenoid from Amorpha fruticosa L., exerts anti-proliferative activity by facilitating β-catenin degradation in hepatocellular carcinoma cells.
Xiaohui Zhu, Xin Wu, +6 authors, Xiangning Zhang.
Oncotarget, 2017 May 27; 8(29). PMID: 28548956    Free PMC article.
USP25 regulates Wnt signaling by controlling the stability of tankyrases.
Daichao Xu, Jianping Liu, +4 authors, Junying Yuan.
Genes Dev, 2017 Jun 18; 31(10). PMID: 28619731    Free PMC article.
Targeting the Wnt Pathway in Cancer: A Review of Novel Therapeutics.
Roya Tabatabai, Yuliya Linhares, +2 authors, Alain Mita.
Target Oncol, 2017 Jun 28; 12(5). PMID: 28653295
Genetic factors affecting EBV copy number in lymphoblastoid cell lines derived from the 1000 Genome Project samples.
Rajendra Mandage, Marco Telford, +7 authors, Gabriel Santpere.
PLoS One, 2017 Jun 28; 12(6). PMID: 28654678    Free PMC article.
Wnt/β-catenin signaling pathway activation reverses gemcitabine resistance by attenuating Beclin1-mediated autophagy in the MG63 human osteosarcoma cell line.
Hao Tao, Feng Chen, +3 authors, Haiyan Li.
Mol Med Rep, 2017 Jun 29; 16(2). PMID: 28656199    Free PMC article.
Hormone dependent uterine epithelial-stromal communication for pregnancy support.
Xiaoqiu Wang, San-Pin Wu, Francesco J DeMayo.
Placenta, 2017 Jul 19; 60 Suppl 1. PMID: 28716426    Free PMC article.
MiR-195 Inhibits Tumor Growth and Metastasis in Papillary Thyroid Carcinoma Cell Lines by Targeting CCND1 and FGF2.
Yali Yin, Shubin Hong, +6 authors, Haipeng Xiao.
Int J Endocrinol, 2017 Jul 26; 2017. PMID: 28740507    Free PMC article.
The role of β-catenin in the initiation and metastasis of TA2 mice spontaneous breast cancer.
Dan Zhang, Fei Fei, +6 authors, Shiwu Zhang.
J Cancer, 2017 Aug 19; 8(11). PMID: 28819413    Free PMC article.
Extracting Intercellular Signaling Network of Cancer Tissues using Ligand-Receptor Expression Patterns from Whole-tumor and Single-cell Transcriptomes.
Joseph X Zhou, Roberto Taramelli, +2 authors, Sui Huang.
Sci Rep, 2017 Aug 20; 7(1). PMID: 28821810    Free PMC article.
De novo metatranscriptome assembly and coral gene expression profile of Montipora capitata with growth anomaly.
Monika Frazier, Martin Helmkampf, +2 authors, Misaki Takabayashi.
BMC Genomics, 2017 Sep 13; 18(1). PMID: 28893194    Free PMC article.
WNT signalling in prostate cancer.
Virginia Murillo-Garzón, Robert Kypta.
Nat Rev Urol, 2017 Sep 13; 14(11). PMID: 28895566
Highly Cited. Review.
Long Noncoding RNA BC032913 as a Novel Therapeutic Target for Colorectal Cancer that Suppresses Metastasis by Upregulating TIMP3.
Jiaxin Lin, Xin Tan, +8 authors, Wenlin Huang.
Mol Ther Nucleic Acids, 2017 Sep 18; 8. PMID: 28918047    Free PMC article.
Polyyne-Enriched Extract from Oplopanax elatus Significantly Ameliorates the Progression of Colon Carcinogenesis in ApcMin/+ Mice.
Xin Qiao, Wei Sun, +5 authors, Chunsu Yuan.
Molecules, 2017 Sep 25; 22(10). PMID: 28937627    Free PMC article.
Extracellular LDLR repeats modulate Wnt signaling activity by promoting LRP6 receptor endocytosis mediated by the Itch E3 ubiquitin ligase.
Sapna Vijayakumar, Guizhong Liu, +6 authors, Stuart A Aaronson.
Genes Cancer, 2017 Oct 03; 8(7-8). PMID: 28966723    Free PMC article.
CLCA1 suppresses colorectal cancer aggressiveness via inhibition of the Wnt/beta-catenin signaling pathway.
Xiaofen Li, Wangxiong Hu, +5 authors, Shu Zheng.
Cell Commun Signal, 2017 Oct 05; 15(1). PMID: 28974231    Free PMC article.
Pathway Analysis with Signaling Hypergraphs.
Anna Ritz, Brendan Avent, T M Murali.
IEEE/ACM Trans Comput Biol Bioinform, 2017 Oct 11; 14(5). PMID: 28991726    Free PMC article.
Human cytomegalovirus infection enhances cell proliferation, migration and upregulation of EMT markers in colorectal cancer-derived stem cell-like cells.
Wan Huai Teo, Hsin-Pai Chen, Jason C Huang, Yu-Jiun Chan.
Int J Oncol, 2017 Oct 20; 51(5). PMID: 29048611    Free PMC article.
Renal carcinoma/kidney progenitor cell chimera organoid as a novel tumorigenesis gene discovery model.
Qi Xu, Sanna Junttila, +9 authors, Seppo J Vainio.
Dis Model Mech, 2017 Nov 01; 10(12). PMID: 29084770    Free PMC article.
Expression of LDL receptor-related proteins (LRPs) in common solid malignancies correlates with patient survival.
Steven L Gonias, Nicki Karimi-Mostowfi, +2 authors, Andrew S Gilder.
PLoS One, 2017 Nov 01; 12(10). PMID: 29088295    Free PMC article.
A partnership with the proteasome; the destructive nature of GSK3.
Holly Robertson, John D Hayes, Calum Sutherland.
Biochem Pharmacol, 2017 Nov 06; 147. PMID: 29102676    Free PMC article.
Regulatory network involving miRNAs and genes in serous ovarian carcinoma.
Haiyan Zhao, Hao Xu, Luchen Xue.
Oncol Lett, 2017 Nov 09; 14(5). PMID: 29113276    Free PMC article.
Co-activation of Hedgehog and Wnt signaling pathways is associated with poor outcomes in triple negative breast cancer.
Kimberly M Arnold, Ryan T Pohlig, Jennifer Sims-Mourtada.
Oncol Lett, 2017 Nov 17; 14(5). PMID: 29142600    Free PMC article.
FH535 Inhibits Proliferation and Motility of Colon Cancer Cells by Targeting Wnt/β-catenin Signaling Pathway.
Yanyan Chen, Xianping Rao, +3 authors, Lisong Teng.
J Cancer, 2017 Nov 22; 8(16). PMID: 29158786    Free PMC article.
Downregulation of nuclear and cytoplasmic Chibby is associated with advanced cervical cancer.
Ming-Chang Yang, Shang-Tao Chien, +3 authors, Yi-Ren Hong.
Oncol Lett, 2017 Nov 29; 14(6). PMID: 29181101    Free PMC article.
Genomic profiles of a hepatoblastoma from a patient with Beckwith-Wiedemann syndrome with uniparental disomy on chromosome 11p15 and germline mutation of APC and PALB2.
Shinn Young Kim, Seung-Hyun Jung, +6 authors, Yeun-Jun Chung.
Oncotarget, 2017 Dec 02; 8(54). PMID: 29190888    Free PMC article.
Primary renal mixed tumor characterized by marked proliferation of osteoblast-like cells with osteoid formation in a swine.
Yuki Oshima, Yuri Nakagawa, +3 authors, Yukichi Tanaka.
J Vet Med Sci, 2017 Dec 05; 80(1). PMID: 29199245    Free PMC article.
The crossroads of breast cancer progression: insights into the modulation of major signaling pathways.
Fernando J Velloso, Arthur Fr Bianco, +8 authors, Ricardo G Correa.
Onco Targets Ther, 2017 Dec 05; 10. PMID: 29200866    Free PMC article.
Decreased expression of interferon-induced protein 2 (IFIT2) by Wnt/β-catenin signaling confers anti-apoptotic properties to colorectal cancer cells.
Tomoyuki Ohsugi, Kiyoshi Yamaguchi, +2 authors, Yoichi Furukawa.
Oncotarget, 2017 Dec 17; 8(59). PMID: 29245969    Free PMC article.
Acquisition of Cholangiocarcinoma Traits during Advanced Hepatocellular Carcinoma Development in Mice.
Liyuan Li, Maoxiang Qian, +9 authors, Liqin Zhu.
Am J Pathol, 2017 Dec 19; 188(3). PMID: 29248454    Free PMC article.
New Insights into the Mechanism of Action of Soluble Klotho.
George D Dalton, Jian Xie, Sung-Wan An, Chou-Long Huang.
Front Endocrinol (Lausanne), 2017 Dec 19; 8. PMID: 29250031    Free PMC article.
Highly Cited. Review.
MGAT1 is a novel transcriptional target of Wnt/β-catenin signaling pathway.
Izzet Akiva, Necla Birgül Iyison.
BMC Cancer, 2018 Jan 10; 18(1). PMID: 29310626    Free PMC article.
Identification of prognostic signature in cancer based on DNA methylation interaction network.
Wei-Lin Hu, Xiong-Hui Zhou.
BMC Med Genomics, 2018 Jan 13; 10(Suppl 4). PMID: 29322932    Free PMC article.
Therapeutic effects of β-elemene via attenuation of the Wnt/β-catenin signaling pathway in cervical cancer cells.
Lufang Wang, Yanyan Zhao, +2 authors, Xin Wu.
Mol Med Rep, 2018 Jan 25; 17(3). PMID: 29363722    Free PMC article.
High-frequency deregulated expression of Wnt signaling pathway members in breast carcinomas.
Zahid Khan, Maha Arafah, +2 authors, Mohammad Saud Alanazi.
Onco Targets Ther, 2018 Feb 03; 11. PMID: 29391809    Free PMC article.
Exon 3 mutations of CTNNB1 drive tumorigenesis: a review.
Chao Gao, Yingmei Wang, +3 authors, Wei Zhang.
Oncotarget, 2018 Feb 13; 9(4). PMID: 29435196    Free PMC article.
Highly Cited. Review.
S100A4 promotes lung tumor development through β-catenin pathway-mediated autophagy inhibition.
Shasha Hou, Tian Tian, +7 authors, Jinhua Zhang.
Cell Death Dis, 2018 Feb 17; 9(3). PMID: 29449540    Free PMC article.
Methylation of secreted frizzled-related protein 1 (SFRP1) promoter downregulates Wnt/β-catenin activity in keloids.
Jiaqi Liu, Huayu Zhu, +8 authors, Dahai Hu.
J Mol Histol, 2018 Feb 20; 49(2). PMID: 29455276
Sp5 negatively regulates the proliferation of HCT116 cells by upregulating the transcription of p27.
Masaya Miyamoto, Tomoatsu Hayashi, Yoshihiro Kawasaki, Tetsu Akiyama.
Oncol Lett, 2018 Feb 20; 15(3). PMID: 29456745    Free PMC article.
Loss of CDX2 gene expression is associated with DNA repair proteins and is a crucial member of the Wnt signaling pathway in liver metastasis of colorectal cancer.
Csaba Tóth, Farkas Sükösd, +3 authors, László Tiszlavicz.
Oncol Lett, 2018 Feb 23; 15(3). PMID: 29467879    Free PMC article.
The multitargeted drug ivermectin: from an antiparasitic agent to a repositioned cancer drug.
Mandy Juarez, Alejandro Schcolnik-Cabrera, Alfonso Dueñas-Gonzalez.
Am J Cancer Res, 2018 Mar 08; 8(2). PMID: 29511601    Free PMC article.
Rigid Peptide Macrocycles from On-Resin Glaser Stapling.
Philip A Cistrone, Anthony P Silvestri, Jordi C J Hintzen, Philip E Dawson.
Chembiochem, 2018 Mar 09; 19(10). PMID: 29516601    Free PMC article.
Phenylethynyl-substituted Heterocycles Inhibit Cyclin D1 and Induce the Expression of Cyclin-dependent Kinase Inhibitor p21Wif1/Cip1 in Colorectal Cancer Cells.
Vitaliy M Sviripa, Liliia M Kril, +8 authors, Chunming Liu.
Medchemcomm, 2018 Mar 13; 9(1). PMID: 29527286    Free PMC article.
PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells.
Monika Raab, Mourad Sanhaji, +9 authors, Klaus Strebhardt.
Nat Commun, 2018 Mar 20; 9(1). PMID: 29549256    Free PMC article.
Fbxw11 promotes the proliferation of lymphocytic leukemia cells through the concomitant activation of NF-κB and β-catenin/TCF signaling pathways.
Lina Wang, Wenli Feng, +5 authors, Guoguang Zheng.
Cell Death Dis, 2018 Mar 21; 9(4). PMID: 29555946    Free PMC article.
Crosstalk Between Peroxisome Proliferator-Activated Receptor Gamma and the Canonical WNT/β-Catenin Pathway in Chronic Inflammation and Oxidative Stress During Carcinogenesis.
Alexandre Vallée, Yves Lecarpentier.
Front Immunol, 2018 May 01; 9. PMID: 29706964    Free PMC article.
Highly Cited. Review.
Ubiquitylation and degradation of adenomatous polyposis coli by MKRN1 enhances Wnt/β-catenin signaling.
Hae-Kyung Lee, Eun-Woo Lee, +7 authors, Jaewhan Song.
Oncogene, 2018 May 02; 37(31). PMID: 29713058
Inhibitory effects of aesculetin on the proliferation of colon cancer cells by the Wnt/β-catenin signaling pathway.
Tao Li, Lei Zhang, Xinkai Huo.
Oncol Lett, 2018 May 05; 15(5). PMID: 29725434    Free PMC article.
Label-free quantitative proteomic analysis identifies CTNNB1 as a direct target of FOXP3 in gastric cancer cells.
Du-Yi Pan, Xiao-Qing Zeng, +7 authors, Shi-Yao Chen.
Oncol Lett, 2018 May 10; 15(5). PMID: 29740487    Free PMC article.
Chibby suppresses aerobic glycolysis and proliferation of nasopharyngeal carcinoma via the Wnt/β-catenin-Lin28/let7-PDK1 cascade.
Cheng-Fu Cai, Guo-Dong Ye, +8 authors, Shu-Yu Yang.
J Exp Clin Cancer Res, 2018 May 17; 37(1). PMID: 29764469    Free PMC article.
Therapeutic Potency of Nanoformulations of siRNAs and shRNAs in Animal Models of Cancers.
Md Emranul Karim, Kyi Kyi Tha, +2 authors, Ezharul Hoque Chowdhury.
Pharmaceutics, 2018 Jun 05; 10(2). PMID: 29861465    Free PMC article.
USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization.
Chenming Wu, Kuntian Luo, +16 authors, Jian Yuan.
Cell Death Differ, 2018 Jun 06; 25(10). PMID: 29867130    Free PMC article.
In vivo base editing of post-mitotic sensory cells.
Wei-Hsi Yeh, Hao Chiang, +2 authors, David R Liu.
Nat Commun, 2018 Jun 07; 9(1). PMID: 29872041    Free PMC article.
Highly Cited.
MicroRNA miR-1249 downregulates adenomatous polyposis coli 2 expression and promotes glioma cells proliferation.
Baojun Fang, Guoliang Li, +2 authors, Gang Li.
Am J Transl Res, 2018 Jun 12; 10(5). PMID: 29887948    Free PMC article.
Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity.
Prachi Jain, Mary Nattakom, +6 authors, Tudorita Tumbar.
Stem Cells, 2018 Jun 26; 36(10). PMID: 29938858    Free PMC article.
Role of Wnt/β-catenin signaling in hepatocellular carcinoma, pathogenesis, and clinical significance.
Ahmed M Khalaf, David Fuentes, +5 authors, Khaled M Elsayes.
J Hepatocell Carcinoma, 2018 Jul 10; 5. PMID: 29984212    Free PMC article.
Highly Cited. Review.
Resveratrol inhibits the growth of gastric cancer via the Wnt/β-catenin pathway.
Hui Dai, Hou-Bo Deng, Ya-Hong Wang, Jia-Juan Guo.
Oncol Lett, 2018 Jul 17; 16(2). PMID: 30008840    Free PMC article.
Expression of miR-30c and BCL-9 in gastric carcinoma tissues and their function in the development of gastric cancer.
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Oncol Lett, 2018 Jul 18; 16(2). PMID: 30013632    Free PMC article.
Transcription factor AP-4 promotes tumorigenic capability and activates the Wnt/β-catenin pathway in hepatocellular carcinoma.
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Theranostics, 2018 Jul 22; 8(13). PMID: 30026867    Free PMC article.
WD40 Repeat Proteins: Signalling Scaffold with Diverse Functions.
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Protein J, 2018 Aug 03; 37(5). PMID: 30069656
Circulating tumor cells as "liquid biopsies" to understand cancer metastasis.
Dennis Woo, Min Yu.
Transl Res, 2018 Aug 04; 201. PMID: 30075099    Free PMC article.
A natural flavonoid lawsonaringenin induces cell cycle arrest and apoptosis in HT-29 colorectal cancer cells by targeting multiple signalling pathways.
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Mol Biol Rep, 2018 Aug 09; 45(5). PMID: 30088202
Glycogen synthase kinase-3 and alternative splicing.
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Wiley Interdiscip Rev RNA, 2018 Aug 18; 9(6). PMID: 30118183    Free PMC article.
Microcystic stromal tumor resected by laparoscopic surgery.
Midori Murakami, Junko Wroblewski, Hidehiro Kawagoe.
Gynecol Minim Invasive Ther, 2017 Jul 01; 6(3). PMID: 30254899    Free PMC article.
Disruption of PD-1 Enhanced the Anti-tumor Activity of Chimeric Antigen Receptor T Cells Against Hepatocellular Carcinoma.
Xingliang Guo, Hua Jiang, +9 authors, Zonghai Li.
Front Pharmacol, 2018 Oct 18; 9. PMID: 30327605    Free PMC article.
Molecular characterization of Wnt pathway and function of β-catenin overexpression in medulloblastoma cell lines.
Lenisa Geron, Karina Bezerra Salomão, +4 authors, Luiz Gonzaga Tone.
Cytotechnology, 2018 Oct 31; 70(6). PMID: 30374857    Free PMC article.
Oncogenic role of SFRP2 in p53-mutant osteosarcoma development via autocrine and paracrine mechanism.
Huensuk Kim, Seungyeul Yoo, +12 authors, Christoph Schaniel.
Proc Natl Acad Sci U S A, 2018 Nov 06; 115(47). PMID: 30385632    Free PMC article.
A novel mouse model of sporadic colon cancer induced by combination of conditional Apc genes and chemical carcinogen in the absence of Cre recombinase.
Jeffrey S Souris, Hannah J Zhang, +6 authors, Marc Bissonnette.
Carcinogenesis, 2019 Mar 13; 40(11). PMID: 30859181    Free PMC article.
Cadherin Signaling in Cancer: Its Functions and Role as a Therapeutic Target.
Weina Yu, Li Yang, Ting Li, Yi Zhang.
Front Oncol, 2019 Oct 23; 9. PMID: 31637214    Free PMC article.
The comprehensive role of E-cadherin in maintaining prostatic epithelial integrity during oncogenic transformation and tumor progression.
Adam Olson, Vien Le, +8 authors, Zijie Sun.
PLoS Genet, 2019 Oct 29; 15(10). PMID: 31658259    Free PMC article.
Screening and computational analysis of colorectal associated non-synonymous polymorphism in CTNNB1 gene in Pakistani population.
Suhail Razak, Nousheen Bibi, +4 authors, Sarwat Jahan.
BMC Med Genet, 2019 Nov 09; 20(1). PMID: 31699039    Free PMC article.
The Alteration of CTNNBIP1 in Lung Cancer.
Jia-Ming Chang, Alexander Charng-Dar Tsai, Way-Ren Huang, Ruo-Chia Tseng.
Int J Mol Sci, 2019 Nov 27; 20(22). PMID: 31766223    Free PMC article.
HERES, a lncRNA that regulates canonical and noncanonical Wnt signaling pathways via interaction with EZH2.
Bo-Hyun You, Jung-Ho Yoon, +3 authors, Jin-Wu Nam.
Proc Natl Acad Sci U S A, 2019 Nov 17; 116(49). PMID: 31732666    Free PMC article.
Low BCL9 expression inhibited ovarian epithelial malignant tumor progression by decreasing proliferation, migration, and increasing apoptosis to cancer cells.
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Cancer Cell Int, 2019 Dec 13; 19. PMID: 31827404    Free PMC article.
DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways.
Faiza Noreen, Taya Küng, +7 authors, Primo Schär.
Clin Epigenetics, 2019 Dec 18; 11(1). PMID: 31842975    Free PMC article.
Activation of tumor-promoting pathways implicated in hepatocellular adenoma/carcinoma, a long-term complication of glycogen storage disease type Ia.
Jun-Ho Cho, Young Mok Lee, Seong-Ho Bae, Janice Y Chou.
Biochem Biophys Res Commun, 2019 Nov 19; 522(1). PMID: 31735334    Free PMC article.
Loss of Wnt7a expression correlates with tumor progression and poor prognosis in colorectal carcinoma.
Se Min Jang, Young Chan Wi, +7 authors, Seung Sam Paik.
Int J Clin Exp Pathol, 2018 Oct 01; 11(10). PMID: 31949573    Free PMC article.
STK31 regulates the proliferation and cell cycle of lung cancer cells via the Wnt/β‑catenin pathway and feedback regulation by c‑myc.
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Oncol Rep, 2020 Jan 03; 43(2). PMID: 31894338    Free PMC article.
High Canonical Wnt/β-Catenin Activity Sensitizes Murine Hematopoietic Stem and Progenitor Cells to DNA Damage.
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Stem Cell Rev Rep, 2019 Dec 05; 16(1). PMID: 31797147    Free PMC article.
Newcastle disease virus mediated apoptosis and migration inhibition of human oral cancer cells: A probable role of β-catenin and matrix metalloproteinase-7.
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Sci Rep, 2019 Jul 28; 9(1). PMID: 31350432    Free PMC article.
Wnt/β-catenin in ischemic myocardium: interactions and signaling pathways as a therapeutic target.
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Heart Fail Rev, 2018 Dec 13; 24(3). PMID: 30539334
p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression.
Sung-Hwan Moon, Chun-Hao Huang, +18 authors, Carol Prives.
Cell, 2018 Dec 26; 176(3). PMID: 30580964    Free PMC article.
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Global analysis of N6-methyladenosine functions and its disease association using deep learning and network-based methods.
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PLoS Comput Biol, 2019 Jan 03; 15(1). PMID: 30601803    Free PMC article.
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Wnt3a disrupts GR-TEAD4-PPARγ2 positive circuits and cytoskeletal rearrangement in a β-catenin-dependent manner during early adipogenesis.
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Cell Death Dis, 2019 Jan 10; 10(1). PMID: 30622240    Free PMC article.
White shark genome reveals ancient elasmobranch adaptations associated with wound healing and the maintenance of genome stability.
Nicholas J Marra, Michael J Stanhope, +13 authors, Mahmood S Shivji.
Proc Natl Acad Sci U S A, 2019 Feb 21; 116(10). PMID: 30782839    Free PMC article.
ING5 inhibits lung cancer invasion and epithelial-mesenchymal transition by inhibiting the WNT/β-catenin pathway.
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Thorac Cancer, 2019 Feb 28; 10(4). PMID: 30810286    Free PMC article.
Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction.
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Nat Commun, 2019 Mar 31; 10(1). PMID: 30926793    Free PMC article.
WNT Signaling in Disease.
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Cells, 2019 Aug 07; 8(8). PMID: 31382613    Free PMC article.
Modelling the effect of subcellular mutations on the migration of cells in the colorectal crypt.
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BMC Bioinformatics, 2020 Mar 05; 21(1). PMID: 32126976    Free PMC article.
Stem cells in normal breast development and breast cancer.
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Cell Prolif, 2003 Oct 03; 36 Suppl 1. PMID: 14521516    Free PMC article.
Highly Cited. Review.
Mathematical model for the cancer stem cell hypothesis.
R Ganguly, I K Puri.
Cell Prolif, 2006 Jan 24; 39(1). PMID: 16426418    Free PMC article.
Mathematical model for chemotherapeutic drug efficacy in arresting tumour growth based on the cancer stem cell hypothesis.
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Cell Prolif, 2007 May 29; 40(3). PMID: 17531079    Free PMC article.
Phosphofructokinase 1 Platelet Isoform Promotes β-Catenin Transactivation for Tumor Development.
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Front Oncol, 2020 Mar 21; 10. PMID: 32195176    Free PMC article.
Hypoxic ER stress suppresses β-catenin expression and promotes cooperation between the transcription factors XBP1 and HIF1α for cell survival.
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J Biol Chem, 2019 Jul 28; 294(37). PMID: 31350332    Free PMC article.
The regulation effect of WNT-RAS signaling in hypothalamic paraventricular nucleus on renal fibrosis.
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NUDT7 Loss Promotes Kras CRC Development.
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Dual inhibition of enhancer of zeste homolog 1/2 overactivates WNT signaling to deplete cancer stem cells in multiple myeloma.
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Cancer Sci, 2018 Oct 22; 110(1). PMID: 30343511    Free PMC article.
Mechanism of Anti-Cancer Activity of Curcumin on Androgen-Dependent and Androgen-Independent Prostate Cancer.
Nurul Azwa Abd Wahab, Nordin H Lajis, +2 authors, Rakesh Naidu.
Nutrients, 2020 Mar 07; 12(3). PMID: 32131560    Free PMC article.
E2F1 mediated DDX11 transcriptional activation promotes hepatocellular carcinoma progression through PI3K/AKT/mTOR pathway.
Yan Yu, Dan Zhao, +7 authors, Guangying Cui.
Cell Death Dis, 2020 Apr 26; 11(4). PMID: 32332880    Free PMC article.
Glucocorticoids Influencing Wnt/β-Catenin Pathway; Multiple Sites, Heterogeneous Effects.
Katalin Meszaros, Attila Patocs.
Molecules, 2020 Mar 29; 25(7). PMID: 32218328    Free PMC article.
Silencing of Wwox Increases Nuclear Import of Dvl proteins in Head and Neck Cancer.
Asuman Celebi, Ceren Orhan, Betul Seyhan, Nur Buyru.
J Cancer, 2020 May 06; 11(14). PMID: 32368285    Free PMC article.
Analyzing the prognostic value of DKK1 expression in human cancers based on bioinformatics.
Ruqiong Wei, Raquel Alarcòn Rodrìguez, +7 authors, Jianwen Xu.
Ann Transl Med, 2020 May 16; 8(8). PMID: 32411775    Free PMC article.
Large intestine embryogenesis: Molecular pathways and related disorders (Review).
Antonios Kostouros, Ioannis Koliarakis, +3 authors, John Tsiaoussis.
Int J Mol Med, 2020 Apr 23; 46(1). PMID: 32319546    Free PMC article.
Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics.
Olesja Popow, João A Paulo, +7 authors, Inke Näthke.
Mol Cancer Res, 2019 Jun 05; 17(9). PMID: 31160382    Free PMC article.
Klotho and the Treatment of Human Malignancies.
Aishani Sachdeva, Jerome Gouge, +4 authors, Irene Chong.
Cancers (Basel), 2020 Jun 27; 12(6). PMID: 32585905    Free PMC article.
The role of secreted frizzled-related protein 2 expression in prostate cancer.
Gillian O'Hurley, Antoinette S Perry, +8 authors, Elaine W Kay.
Histopathology, 2011 Dec 20; 59(6). PMID: 22175903    Free PMC article.
Atonal bHLH transcription factor 1 is an important factor for maintaining the balance of cell proliferation and differentiation in tumorigenesis.
Ying Fu, Sha-Sha Yuan, +2 authors, Xiao-Jiang Quan.
Oncol Lett, 2020 Aug 13; 20(3). PMID: 32782577    Free PMC article.
Signatures of co-deregulated genes and their transcriptional regulators in colorectal cancer.
Natalia Mastrogamvraki, Apostolos Zaravinos.
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Adrenal Incidentaloma.
Mark Sherlock, Andrew Scarsbrook, +4 authors, Paul M Stewart.
Endocr Rev, 2020 Apr 09; 41(6). PMID: 32266384    Free PMC article.
Growth retardation-responsive analysis of mRNAs and long noncoding RNAs in the liver tissue of Leiqiong cattle.
Lingxuan Kong, Guangbin Liu, +6 authors, Yaokun Li.
Sci Rep, 2020 Sep 02; 10(1). PMID: 32868811    Free PMC article.
Protective effect of propofol on hydrogen peroxide-induced human esophageal carcinoma via blocking the Wnt/β-catenin signaling pathway.
Jian-Jun Xue, Ling-Yun Zhang, +3 authors, Ke-Hu Yang.
Iran J Basic Med Sci, 2019 Jan 11; 21(12). PMID: 30627375    Free PMC article.
G-protein-coupled receptor kinase-5 promotes glioblastoma progression by targeting the nuclear factor kappa B pathway.
Yang Yang, Jing-Jing Wu, +6 authors, Chao-Shi Niu.
Am J Transl Res, 2019 Jan 22; 10(11). PMID: 30662593    Free PMC article.
The Expression Patterns of FAM83H and PANX2 Are Associated With Shorter Survival of Clear Cell Renal Cell Carcinoma Patients.
Kyoung Min Kim, Usama Khamis Hussein, +9 authors, Kyu Yun Jang.
Front Oncol, 2019 Feb 07; 9. PMID: 30723706    Free PMC article.
miR-600 inhibits lung cancer via downregulating the expression of METTL3.
Wenwen Wei, Baosheng Huo, Xiulan Shi.
Cancer Manag Res, 2019 Feb 19; 11. PMID: 30774445    Free PMC article.
Highly Cited.
HDAC I inhibitor regulates RUNX2 transactivation through canonical and non-canonical Wnt signaling in aortic valvular interstitial cells.
Shao-Jung Li, Yu-Hsun Kao, +2 authors, Yi-Jen Chen.
Am J Transl Res, 2019 Mar 23; 11(2). PMID: 30899376    Free PMC article.
Targeting Wnt Signaling via Notch in Intestinal Carcinogenesis.
Elke Kaemmerer, Min Kyung Jeon, +2 authors, Nikolaus Gassler.
Cancers (Basel), 2019 Apr 21; 11(4). PMID: 31003440    Free PMC article.
Clinicohistopathological implications of phosphoserine 9 glycogen synthase kinase-3β/ β-catenin in urinary bladder cancer patients.
Niharika Maurya, Rinni Singh, +4 authors, Minal Garg.
World J Clin Oncol, 2019 May 23; 10(4). PMID: 31114749    Free PMC article.
Osteosarcoma progression is associated with increased nuclear levels and transcriptional activity of activated β-Catenin.
Noureen Ali, Geetha Venkateswaran, +7 authors, Sujata Persad.
Genes Cancer, 2019 Jul 02; 10(3-4). PMID: 31258833    Free PMC article.
MiR-509-5p improves the proliferative and invasive abilities of papillary thyroid carcinoma cells by inhibiting SFRP1.
Chunxiao Yang, Yingluan Wang, +3 authors, Xingwang Yang.
Arch Med Sci, 2019 Jul 31; 15(4). PMID: 31360191    Free PMC article.
Therapeutic Targeting of Cancer Stem Cells via Modulation of the Renin-Angiotensin System.
Imogen M Roth, Agadha C Wickremesekera, +2 authors, Swee T Tan.
Front Oncol, 2019 Aug 24; 9. PMID: 31440473    Free PMC article.
Metastatic components in colorectal cancer.
Marjan Hajimoradi Javarsiani, Shagayegh Haghjooy Javanmard, Francesca Colonna.
J Res Med Sci, 2019 Sep 17; 24. PMID: 31523261    Free PMC article.
Her2 promotes early dissemination of breast cancer by suppressing the p38-MK2-Hsp27 pathway that is targetable by Wip1 inhibition.
Juan Wang, Guanwen Wang, +10 authors, Peiqing Sun.
Oncogene, 2020 Aug 28; 39(40). PMID: 32848211    Free PMC article.
Matrix Metalloprotease-7 Mediates Nucleolar Assembly and Intra-nucleolar Cleaving p53 in Gefitinib-Resistant Cancer Stem Cells.
Wei-Hsuan Yu, Erxi Wu, +6 authors, Chong-Jen Yu.
iScience, 2020 Oct 23; 23(10). PMID: 33089100    Free PMC article.
A Novel Imidazopyridine Derivative Exhibits Anticancer Activity in Breast Cancer by Inhibiting Wnt/β‑catenin Signaling.
Liu-Jun He, Dong-Lin Yang, +6 authors, Zhong-Zhu Chen.
Onco Targets Ther, 2020 Oct 30; 13. PMID: 33116593    Free PMC article.
Rho Family of Ras-Like GTPases in Early-Branching Animals.
Silvestar Beljan, Maja Herak Bosnar, Helena Ćetković.
Cells, 2020 Oct 18; 9(10). PMID: 33066017    Free PMC article.
Signal transduction pathway mutations in gastrointestinal (GI) cancers: a systematic review and meta-analysis.
Alireza Tabibzadeh, Fahimeh Safarnezhad Tameshkel, +11 authors, Mohammad Hadi Karbalaie Niya.
Sci Rep, 2020 Nov 01; 10(1). PMID: 33127962    Free PMC article.
Systematic Review.
Effects of naringin on reversing cisplatin resistance and the Wnt/β-catenin pathway in human ovarian cancer SKOV3/CDDP cells.
Hong Zhu, Xia Zou, +2 authors, Jun Gao.
J Int Med Res, 2020 Oct 23; 48(10). PMID: 33086930    Free PMC article.
Exosomal arrow (Arr)/lipoprotein receptor protein 6 (LRP6) in Drosophila melanogaster increases the extracellular level of Sol narae (Sona) in a Wnt-independent manner.
Jeong-Hoon Han, Yeon Kim, Kyung-Ok Cho.
Cell Death Dis, 2020 Nov 04; 11(11). PMID: 33139721    Free PMC article.
Role of Polycomb Complexes in Normal and Malignant Plasma Cells.
Emmanuel Varlet, Sara Ovejero, +2 authors, Jerome Moreaux.
Int J Mol Sci, 2020 Nov 01; 21(21). PMID: 33126754    Free PMC article.
Expression of secreted Wnt antagonists in gastrointestinal tissues: potential role in stem cell homeostasis.
T Byun, M Karimi, +3 authors, R F Holcombe.
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Wnt signaling promotes regeneration in the retina of adult mammals.
Fumitaka Osakada, Sotaro Ooto, +3 authors, Masayo Takahashi.
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E2F1 represses beta-catenin/TCF activity by direct up-regulation of Siah1.
Wei Xie, Lei Jin, Yide Mei, Mian Wu.
J Cell Mol Med, 2010 Feb 27; 13(8B). PMID: 20187294    Free PMC article.
Cancer chemoprevention by carotenoids.
Takuji Tanaka, Masahito Shnimizu, Hisataka Moriwaki.
Molecules, 2012 Mar 16; 17(3). PMID: 22418926    Free PMC article.
E proteins in lymphocyte development and lymphoid diseases.
Ian Belle, Yuan Zhuang.
Curr Top Dev Biol, 2014 Sep 25; 110. PMID: 25248476    Free PMC article.
WNT Takes Two to Tango: Molecular Links between the Circadian Clock and the Cell Cycle in Adult Stem Cells.
Toru Matsu-Ura, Sean R Moore, Christian I Hong.
J Biol Rhythms, 2017 Dec 27; 33(1). PMID: 29277155    Free PMC article.
BIOPYDB: A Dynamic Human Cell Specific Biochemical Pathway Database with Advanced Computational Analyses Platform.
Saikat Chowdhury, Noopur Sinha, +4 authors, Ram Rup Sarkar.
J Integr Bioinform, 2018 Mar 17; 15(3). PMID: 29547394    Free PMC article.
Targeting cancer stem cell signature gene SMOC-2 Overcomes chemoresistance and inhibits cell proliferation of endometrial carcinoma.
Huan Lu, Dan-Dan Ju, +8 authors, Rong Zhang.
EBioMedicine, 2018 Dec 31; 40. PMID: 30594556    Free PMC article.
N-Terminal Domain Mediated Regulation of RORα1 Inhibits Invasive Growth in Prostate Cancer.
Su Chan Park, Il-Geun Park, Hyunkyung Kim, Ji Min Lee.
Int J Mol Sci, 2019 Apr 17; 20(7). PMID: 30987323    Free PMC article.
Interplay Between SOX9, Wnt/β-Catenin and Androgen Receptor Signaling in Castration-Resistant Prostate Cancer.
Namrata Khurana, Suresh C Sikka.
Int J Mol Sci, 2019 Apr 28; 20(9). PMID: 31027362    Free PMC article.
Effects of Intestinal Microbial⁻Elaborated Butyrate on Oncogenic Signaling Pathways.
Jiezhong Chen, Kong-Nan Zhao, Luis Vitetta.
Nutrients, 2019 May 10; 11(5). PMID: 31067776    Free PMC article.
Hyper-O-GlcNAcylation promotes epithelial-mesenchymal transition in endometrial cancer cells.
Nicole Morin Jaskiewicz, David H Townson.
Oncotarget, 2019 May 14; 10(30). PMID: 31080560    Free PMC article.
FAM83H is involved in stabilization of β-catenin and progression of osteosarcomas.
Kyoung Min Kim, Usama Khamis Hussein, +11 authors, Kyu Yun Jang.
J Exp Clin Cancer Res, 2019 Jun 20; 38(1). PMID: 31215499    Free PMC article.
TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer.
Karthik Aripaka, Shyam Kumar Gudey, +6 authors, Marene Landström.
EBioMedicine, 2019 Jul 03; 45. PMID: 31262711    Free PMC article.
Conceptual Evolution of Cell Signaling.
Arathi Nair, Prashant Chauhan, Bhaskar Saha, Katharina F Kubatzky.
Int J Mol Sci, 2019 Jul 07; 20(13). PMID: 31277491    Free PMC article.
Base editing: advances and therapeutic opportunities.
Elizabeth M Porto, Alexis C Komor, Ian M Slaymaker, Gene W Yeo.
Nat Rev Drug Discov, 2020 Oct 21; 19(12). PMID: 33077937    Free PMC article.
Transcriptome Analysis Reveals High Similarities between Adult Human Cardiac Stem Cells and Neural Crest-Derived Stem Cells.
Anna L Höving, Katharina Sielemann, +3 authors, Christian Kaltschmidt.
Biology (Basel), 2020 Dec 05; 9(12). PMID: 33271866    Free PMC article.
Anti-tumor activity of resveratrol against gastric cancer: a review of recent advances with an emphasis on molecular pathways.
Milad Ashrafizadeh, Hossein Rafiei, +2 authors, Saeed Samarghandian.
Cancer Cell Int, 2021 Jan 23; 21(1). PMID: 33478512    Free PMC article.
Echogenic, Ultrasound-Sensitive Chitosan Nanodroplets for Spatiotemporally Controlled DKK-2 Gene Delivery to Prostate Cancer Cells.
Xinxin Liu, Dandan Shi, +6 authors, Jie Li.
Int J Nanomedicine, 2021 Jan 26; 16. PMID: 33488078    Free PMC article.
G3BP1 promotes human breast cancer cell proliferation through coordinating with GSK-3β and stabilizing β-catenin.
Cong-Hui Zhang, Hong Liu, +3 authors, Rong-Guang Shao.
Acta Pharmacol Sin, 2021 Feb 05; 42(11). PMID: 33536604    Free PMC article.
Overexpression of Forkhead Box L1 (FOXL1) Inhibits the Proliferation and Invasion of Breast Cancer Cells.
Jiateng Zhong, Haijun Wang, +2 authors, Hui Wang.
Oncol Res, 2016 Dec 13; 25(6). PMID: 27938507    Free PMC article.
Knockdown of Tripartite Motif-Containing Protein 37 (TRIM37) Inhibits the Proliferation and Tumorigenesis in Colorectal Cancer Cells.
Ping Zhao, Hai-Tao Guan, +3 authors, Xi-Jing Wang.
Oncol Res, 2017 Jan 14; 25(1). PMID: 28081740    Free PMC article.
Loss of CTNNB1 exon 3 in sclerosing angiomatoid nodular transformation of the spleen.
Sarp Uzun, Özge Özcan, +6 authors, Aytekin Akyol.
Virchows Arch, 2021 Mar 03; 479(4). PMID: 33650044
Comprehending the crosstalk between Notch, Wnt and Hedgehog signaling pathways in oral squamous cell carcinoma - clinical implications.
Anjali P Patni, M K Harishankar, +3 authors, Arikketh Devi.
Cell Oncol (Dordr), 2021 Mar 12; 44(3). PMID: 33704672
Modulation of post-translational modifications in β-catenin and LRP6 inhibits Wnt signaling pathway in pancreatic cancer.
Bharti Garg, Bhuwan Giri, +3 authors, Ashok Saluja.
Cancer Lett, 2016 Dec 07; 388. PMID: 27919787    Free PMC article.
A Wnt-mediated phenotype switch along the epithelial-mesenchymal axis defines resistance and invasion downstream of ionising radiation in oral squamous cell carcinoma.
Fatemeh Zolghadr, Nigel Tse, +10 authors, Naisana Seyedasli.
Br J Cancer, 2021 Apr 01; 124(12). PMID: 33785878    Free PMC article.
The Scaffold Protein Axin Promotes Signaling Specificity within the Wnt Pathway by Suppressing Competing Kinase Reactions.
Maire Gavagan, Erin Fagnan, Elizabeth B Speltz, Jesse G Zalatan.
Cell Syst, 2020 Jun 20; 10(6). PMID: 32553184    Free PMC article.
Pancreatic Cancer and Therapy: Role and Regulation of Cancer Stem Cells.
Susmita Barman, Iram Fatima, Amar B Singh, Punita Dhawan.
Int J Mol Sci, 2021 May 06; 22(9). PMID: 33946266    Free PMC article.
CORO6 Promotes Cell Growth and Invasion of Clear Cell Renal Cell Carcinoma via Activation of WNT Signaling.
Xinjun Wang, Yiming Xiao, +2 authors, Guangcheng Luo.
Front Cell Dev Biol, 2021 May 25; 9. PMID: 34026752    Free PMC article.
Targeting Wnt Signaling in Endometrial Cancer.
Iram Fatima, Susmita Barman, +2 authors, Vishal Chandra.
Cancers (Basel), 2021 Jun 03; 13(10). PMID: 34068065    Free PMC article.
Aspects of the Tumor Microenvironment Involved in Immune Resistance and Drug Resistance.
Khalil Khalaf, Doris Hana, +3 authors, Mariusz Kaczmarek.
Front Immunol, 2021 Jun 15; 12. PMID: 34122412