Journal Article
. 2002 Dec;347(25).
doi: 10.1056/NEJMoa021967.

A gene-expression signature as a predictor of survival in breast cancer

Marc J van de Vijver 1 Yudong D He  Laura J van't Veer  Hongyue Dai  Augustinus A M Hart  Dorien W Voskuil  George J Schreiber  Johannes L Peterse  Chris Roberts  Matthew J Marton  Mark Parrish  Douwe Atsma  Anke Witteveen  Annuska Glas  Leonie Delahaye  Tony van der Velde  Harry Bartelink  Sjoerd Rodenhuis  Emiel T Rutgers  Stephen H Friend  René Bernards  
Affiliations
  • PMID: 12490681
  •     2008 citations

Abstract

Background: A more accurate means of prognostication in breast cancer will improve the selection of patients for adjuvant systemic therapy.

Methods: Using microarray analysis to evaluate our previously established 70-gene prognosis profile, we classified a series of 295 consecutive patients with primary breast carcinomas as having a gene-expression signature associated with either a poor prognosis or a good prognosis. All patients had stage I or II breast cancer and were younger than 53 years old; 151 had lymph-node-negative disease, and 144 had lymph-node-positive disease. We evaluated the predictive power of the prognosis profile using univariable and multivariable statistical analyses.

Results: Among the 295 patients, 180 had a poor-prognosis signature and 115 had a good-prognosis signature, and the mean (+/-SE) overall 10-year survival rates were 54.6+/-4.4 percent and 94.5+/-2.6 percent, respectively. At 10 years, the probability of remaining free of distant metastases was 50.6+/-4.5 percent in the group with a poor-prognosis signature and 85.2+/-4.3 percent in the group with a good-prognosis signature. The estimated hazard ratio for distant metastases in the group with a poor-prognosis signature, as compared with the group with the good-prognosis signature, was 5.1 (95 percent confidence interval, 2.9 to 9.0; P<0.001). This ratio remained significant when the groups were analyzed according to lymph-node status. Multivariable Cox regression analysis showed that the prognosis profile was a strong independent factor in predicting disease outcome.

Conclusions: The gene-expression profile we studied is a more powerful predictor of the outcome of disease in young patients with breast cancer than standard systems based on clinical and histologic criteria.

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Miguel Martín.
Clin Transl Oncol, 2006 Apr 25; 8(1). PMID: 16632434
Review.
Differential expression of selected histone modifier genes in human solid cancers.
Hilal Ozdağ, Andrew E Teschendorff, +12 authors, Carlos Caldas.
BMC Genomics, 2006 Apr 28; 7. PMID: 16638127    Free PMC article.
The molecular portraits of breast tumors are conserved across microarray platforms.
Zhiyuan Hu, Cheng Fan, +28 authors, Charles M Perou.
BMC Genomics, 2006 Apr 29; 7. PMID: 16643655    Free PMC article.
Highly Cited.
In vitro transcription amplification and labeling methods contribute to the variability of gene expression profiling with DNA microarrays.
Changqing Ma, Maureen Lyons-Weiler, +4 authors, Federico A Monzon.
J Mol Diagn, 2006 Apr 29; 8(2). PMID: 16645204    Free PMC article.
Genomic platforms for cancer research: potential diagnostic and prognostic applications in clinical oncology.
Pedro Jares, Elías Campo.
Clin Transl Oncol, 2006 May 02; 8(3). PMID: 16648115
Review.
A comparison of univariate and multivariate gene selection techniques for classification of cancer datasets.
Carmen Lai, Marcel J T Reinders, Laura J van't Veer, Lodewyk F A Wessels.
BMC Bioinformatics, 2006 May 04; 7. PMID: 16670007    Free PMC article.
Characterizing disease states from topological properties of transcriptional regulatory networks.
David P Tuck, Harriet M Kluger, Yuval Kluger.
BMC Bioinformatics, 2006 May 04; 7. PMID: 16670008    Free PMC article.
Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: a Cancer and Leukemia Group B study.
Michael D Radmacher, Guido Marcucci, +11 authors, Cancer and Leukemia Group B.
Blood, 2006 May 04; 108(5). PMID: 16670265    Free PMC article.
Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms.
Therese Sørlie, Yulei Wang, +4 authors, Anne-Lise Børresen-Dale.
BMC Genomics, 2006 May 30; 7. PMID: 16729877    Free PMC article.
Highly Cited.
Personalized medicine and development of targeted therapies: The upcoming challenge for diagnostic molecular pathology. A review.
Manfred Dietel, Christine Sers.
Virchows Arch, 2006 Jun 01; 448(6). PMID: 16736190
Review.
Noise-injected neural networks show promise for use on small-sample expression data.
Jianping Hua, James Lowey, Zixiang Xiong, Edward R Dougherty.
BMC Bioinformatics, 2006 Jun 02; 7. PMID: 16737545    Free PMC article.
A population-based study of tumor gene expression and risk of breast cancer death among lymph node-negative patients.
Laurel A Habel, Steven Shak, +12 authors, Charles P Quesenberry.
Breast Cancer Res, 2006 Jun 02; 8(3). PMID: 16737553    Free PMC article.
Highly Cited.
Gene expression profiling as a window into idiopathic pulmonary fibrosis pathogenesis: can we identify the right target genes?
Naftali Kaminski, Ivan O Rosas.
Proc Am Thorac Soc, 2006 Jun 02; 3(4). PMID: 16738198    Free PMC article.
Review.
Prognostic factors in prostate cancer.
A Buhmeida, S Pyrhönen, M Laato, Y Collan.
Diagn Pathol, 2006 Jun 09; 1. PMID: 16759347    Free PMC article.
A clinical prognostic prediction of lymph node-negative breast cancer by gene expression profiles.
Dingfeng Jiang, Naiqing Zhao.
J Cancer Res Clin Oncol, 2006 Jun 09; 132(9). PMID: 16761122
Bone sialoprotein mediates the tumor cell-targeted prometastatic activity of transforming growth factor beta in a mouse model of breast cancer.
Jeong-Seok Nam, Adam M Suchar, +9 authors, Lalage M Wakefield.
Cancer Res, 2006 Jun 17; 66(12). PMID: 16778210    Free PMC article.
Genomic analysis of circulating cells: a window into atherosclerosis.
Ju-Gyeong Kang, Willmar D Patino, Satoaki Matoba, Paul M Hwang.
Trends Cardiovasc Med, 2006 Jun 20; 16(5). PMID: 16781950    Free PMC article.
Review.
The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis.
Susan J Cleator, Trevor J Powles, +6 authors, Mitch Dowsett.
Breast Cancer Res, 2006 Jun 23; 8(3). PMID: 16790077    Free PMC article.
Identification of prognostic signatures in breast cancer microarray data using Bayesian techniques.
L Carrivick, S Rogers, +3 authors, C Cooper.
J R Soc Interface, 2006 Jul 20; 3(8). PMID: 16849266    Free PMC article.
Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer.
Marcia V Fournier, Katherine J Martin, +4 authors, Mina J Bissell.
Cancer Res, 2006 Jul 20; 66(14). PMID: 16849555    Free PMC article.
Chemokine (C-C motif) ligand 2 mediates the prometastatic effect of dysadherin in human breast cancer cells.
Jeong-Seok Nam, Mi-Jin Kang, +6 authors, Lalage M Wakefield.
Cancer Res, 2006 Jul 20; 66(14). PMID: 16849564    Free PMC article.
Breast cancer prognosis by combinatorial analysis of gene expression data.
Gabriela Alexe, Sorin Alexe, +4 authors, Peter L Hammer.
Breast Cancer Res, 2006 Jul 25; 8(4). PMID: 16859500    Free PMC article.
A method for high-throughput gene expression signature analysis.
David Peck, Emily D Crawford, +3 authors, Justin Lamb.
Genome Biol, 2006 Jul 25; 7(7). PMID: 16859521    Free PMC article.
Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours.
G P Skliris, E Leygue, +2 authors, L C Murphy.
Br J Cancer, 2006 Aug 02; 95(5). PMID: 16880783    Free PMC article.
[Prognostic factors in ductal carcinoma in situ].
A Lebeau.
Pathologe, 2006 Aug 10; 27(5). PMID: 16896676
Comparison of gene expression profiles in core biopsies and corresponding surgical breast cancer samples.
Rosanna Zanetti-Dällenbach, Vincent Vuaroqueaux, +6 authors, Serenella Eppenberger-Castori.
Breast Cancer Res, 2006 Aug 22; 8(4). PMID: 16919157    Free PMC article.
Genetic prognostic index influences patient outcome for node-positive breast cancer.
Shin-Ichi Asaka, Takashi Fujimoto, +2 authors, Masamitsu Onda.
Surg Today, 2006 Aug 29; 36(9). PMID: 16937283
Discovery and validation of breast cancer subtypes.
Amy V Kapp, Stefanie S Jeffrey, +7 authors, Robert Tibshirani.
BMC Genomics, 2006 Sep 13; 7. PMID: 16965636    Free PMC article.
A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer.
Jérôme Eeckhoute, Jason S Carroll, +2 authors, Myles Brown.
Genes Dev, 2006 Sep 19; 20(18). PMID: 16980581    Free PMC article.
Highly Cited.
Can anesthetic technique for primary breast cancer surgery affect recurrence or metastasis?
Aristomenis K Exadaktylos, Donal J Buggy, +2 authors, Daniel I Sessler.
Anesthesiology, 2006 Sep 29; 105(4). PMID: 17006061    Free PMC article.
Highly Cited.
Gene expression signatures of morphologically normal breast tissue identify basal-like tumors.
Greg Finak, Svetlana Sadekova, +8 authors, Morag Park.
Breast Cancer Res, 2006 Oct 24; 8(5). PMID: 17054791    Free PMC article.
Predicting a local recurrence after breast-conserving therapy by gene expression profiling.
Dimitry S A Nuyten, Bas Kreike, +8 authors, Marc J van de Vijver.
Breast Cancer Res, 2006 Oct 31; 8(5). PMID: 17069664    Free PMC article.
Converting a breast cancer microarray signature into a high-throughput diagnostic test.
Annuska M Glas, Arno Floore, +9 authors, Laura J Van't Veer.
BMC Genomics, 2006 Nov 01; 7. PMID: 17074082    Free PMC article.
Highly Cited.
High-throughput genomic technology in research and clinical management of breast cancer. Exploiting the potential of gene expression profiling: is it ready for the clinic?
Andrew H Sims, Kai Ren Ong, Robert B Clarke, Anthony Howell.
Breast Cancer Res, 2006 Nov 02; 8(5). PMID: 17076877    Free PMC article.
Review.
A consensus prognostic gene expression classifier for ER positive breast cancer.
Andrew E Teschendorff, Ali Naderi, +5 authors, Carlos Caldas.
Genome Biol, 2006 Nov 02; 7(10). PMID: 17076897    Free PMC article.
Clinical proteomics: present and future prospects.
Nicole M Verrills.
Clin Biochem Rev, 2006 Nov 02; 27(2). PMID: 17077880    Free PMC article.
Identification of differentially expressed genes in HPV-positive and HPV-negative oropharyngeal squamous cell carcinomas.
Ivan Martinez, Jun Wang, +2 authors, Saleem A Khan.
Eur J Cancer, 2006 Nov 03; 43(2). PMID: 17079134    Free PMC article.
Gene expression patterns in blood leukocytes discriminate patients with acute infections.
Octavio Ramilo, Windy Allman, +8 authors, Damien Chaussabel.
Blood, 2006 Nov 16; 109(5). PMID: 17105821    Free PMC article.
Highly Cited.
Prognostic value of PAI1 in invasive breast cancer: evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression.
Mark D Sternlicht, Alison M Dunning, +7 authors, Zena Werb.
Cancer Epidemiol Biomarkers Prev, 2006 Nov 23; 15(11). PMID: 17119035    Free PMC article.
Prognostic model of stage II non-small cell lung cancer by a discriminant analysis of the immunohistochemical protein expression.
Takayuki Kohri, Masayuki Sugano, +4 authors, Takashi Nakajima.
Surg Today, 2006 Nov 24; 36(12). PMID: 17123130
A gene expression signature associated with survival in metastatic melanoma.
Susanna Mandruzzato, Andrea Callegaro, +9 authors, Paola Zanovello.
J Transl Med, 2006 Nov 30; 4. PMID: 17129373    Free PMC article.
Improved breast cancer prognosis through the combination of clinical and genetic markers.
Yijun Sun, Steve Goodison, +2 authors, William Farmerie.
Bioinformatics, 2006 Nov 30; 23(1). PMID: 17130137    Free PMC article.
The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer.
Emily E Bosco, Ying Wang, +5 authors, Erik S Knudsen.
J Clin Invest, 2006 Dec 13; 117(1). PMID: 17160137    Free PMC article.
Measuring proliferation in breast cancer: practicalities and applications.
Mark J Beresford, George D Wilson, Andreas Makris.
Breast Cancer Res, 2006 Dec 14; 8(6). PMID: 17164010    Free PMC article.
Review.
Classification methods for the development of genomic signatures from high-dimensional data.
Hojin Moon, Hongshik Ahn, +3 authors, James J Chen.
Genome Biol, 2006 Dec 22; 7(12). PMID: 17181863    Free PMC article.
A mouse stromal response to tumor invasion predicts prostate and breast cancer patient survival.
Marina Bacac, Paolo Provero, +3 authors, Ivan Stamenkovic.
PLoS One, 2006 Dec 22; 1. PMID: 17183660    Free PMC article.
A gene expression signature predicts survival of patients with stage I non-small cell lung cancer.
Yan Lu, William Lemon, +9 authors, Ming You.
PLoS Med, 2006 Dec 30; 3(12). PMID: 17194181    Free PMC article.
Highly Cited.
Microarray-based analysis of ventilator-induced lung injury.
Mark M Wurfel.
Proc Am Thorac Soc, 2007 Jan 05; 4(1). PMID: 17202295    Free PMC article.
Review.
CENP-F expression is associated with poor prognosis and chromosomal instability in patients with primary breast cancer.
Sallyann L O'Brien, Ailís Fagan, +11 authors, William M Gallagher.
Int J Cancer, 2007 Jan 06; 120(7). PMID: 17205517    Free PMC article.
Heterologous tissue culture expression signature predicts human breast cancer prognosis.
Eun Sung Park, Ju-Seog Lee, +4 authors, J Frederic Mushinski.
PLoS One, 2007 Jan 09; 2(1). PMID: 17206280    Free PMC article.
An approach to the validation of novel molecular markers of breast cancer via TMA-based FISH scanning.
Raymond R Tubbs, Eric Swain, James D Pettay, David G Hicks.
J Mol Histol, 2007 Jan 11; 38(2). PMID: 17211577
Targeting TACE-dependent EGFR ligand shedding in breast cancer.
Paraic A Kenny, Mina J Bissell.
J Clin Invest, 2007 Jan 16; 117(2). PMID: 17218988    Free PMC article.
Serum proteome profiling detects myelodysplastic syndromes and identifies CXC chemokine ligands 4 and 7 as markers for advanced disease.
Manuel Aivado, Dimitrios Spentzos, +17 authors, Towia A Libermann.
Proc Natl Acad Sci U S A, 2007 Jan 16; 104(4). PMID: 17220270    Free PMC article.
Prognostic implications of immunohistochemically detected YKL-40 expression in breast cancer.
Steve H Kim, Kasturi Das, +2 authors, Meera Hameed.
World J Surg Oncol, 2007 Feb 09; 5. PMID: 17286869    Free PMC article.
A new molecular breast cancer subclass defined from a large scale real-time quantitative RT-PCR study.
Maïa Chanrion, Hélène Fontaine, +5 authors, Jean-Marie Darbon.
BMC Cancer, 2007 Mar 07; 7. PMID: 17338809    Free PMC article.
Microarray analysis of human leucocyte subsets: the advantages of positive selection and rapid purification.
Paul A Lyons, Maria Koukoulaki, +4 authors, Kenneth G C Smith.
BMC Genomics, 2007 Mar 07; 8. PMID: 17338817    Free PMC article.
Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles.
Daniel R Rhodes, Shanker Kalyana-Sundaram, +10 authors, Arul M Chinnaiyan.
Neoplasia, 2007 Mar 16; 9(2). PMID: 17356713    Free PMC article.
Highly Cited.
Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas.
Nathan D Price, Jonathan Trent, +7 authors, Wei Zhang.
Proc Natl Acad Sci U S A, 2007 Mar 16; 104(9). PMID: 17360660    Free PMC article.
Oestrogen signalling inhibits invasive phenotype by repressing RelB and its target BCL2.
Xiaobo Wang, Karine Belguise, +5 authors, Gail E Sonenshein.
Nat Cell Biol, 2007 Mar 21; 9(4). PMID: 17369819    Free PMC article.
Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome.
Hector R Wong, Thomas P Shanley, +15 authors, Genomics of Pediatric SIRS/Septic Shock Investigators.
Physiol Genomics, 2007 Mar 22; 30(2). PMID: 17374846    Free PMC article.
Highly Cited.
An overview of prognostic factors for long-term survivors of breast cancer.
Isabelle Soerjomataram, Marieke W J Louwman, +2 authors, Jan Willem W Coebergh.
Breast Cancer Res Treat, 2007 Mar 23; 107(3). PMID: 17377838    Free PMC article.
Highly Cited. Review.
Expression genomics in breast cancer research: microarrays at the crossroads of biology and medicine.
Lance D Miller, Edison T Liu.
Breast Cancer Res, 2007 Apr 03; 9(2). PMID: 17397520    Free PMC article.
Review.
CARD15 status and familial predisposition for Crohn's disease and colonic gene expression.
Claudio Csillag, Ole Haagen Nielsen, +3 authors, Finn Cilius Nielsen.
Dig Dis Sci, 2007 Apr 06; 52(8). PMID: 17410442
Meta-analysis of several gene lists for distinct types of cancer: a simple way to reveal common prognostic markers.
Xinan Yang, Xiao Sun.
BMC Bioinformatics, 2007 Apr 07; 8. PMID: 17411443    Free PMC article.
Lung metastasis genes couple breast tumor size and metastatic spread.
Andy J Minn, Gaorav P Gupta, +10 authors, Joan Massagué.
Proc Natl Acad Sci U S A, 2007 Apr 11; 104(16). PMID: 17420468    Free PMC article.
Highly Cited.
Identification of a robust gene signature that predicts breast cancer outcome in independent data sets.
James E Korkola, Ekaterina Blaveri, +7 authors, Frederic M Waldman.
BMC Cancer, 2007 Apr 13; 7. PMID: 17428335    Free PMC article.
Prognostic significance of bcl-2 expression in stage III breast cancer patients who had received doxorubicin and cyclophosphamide followed by paclitaxel as adjuvant chemotherapy.
Kyung-Hun Lee, Seock-Ah Im, +10 authors, Yung-Jue Bang.
BMC Cancer, 2007 Apr 14; 7. PMID: 17430582    Free PMC article.
Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity.
Lao H Saal, Peter Johansson, +14 authors, Ramon Parsons.
Proc Natl Acad Sci U S A, 2007 Apr 25; 104(18). PMID: 17452630    Free PMC article.
Highly Cited.
The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans.
Alana L Welm, Julie B Sneddon, +4 authors, J Michael Bishop.
Proc Natl Acad Sci U S A, 2007 Apr 26; 104(18). PMID: 17456594    Free PMC article.
Molecular profiling in breast cancer.
Shannon R Morris, Lisa A Carey.
Rev Endocr Metab Disord, 2007 Apr 28; 8(3). PMID: 17464566
Review.
Do we need to redefine a cancer metastasis and staging definitions?
Danny R Welch.
Breast Dis, 2007 May 03; 26. PMID: 17473362    Free PMC article.
Review.
Three methods for optimization of cross-laboratory and cross-platform microarray expression data.
Phillip Stafford, Marcel Brun.
Nucleic Acids Res, 2007 May 05; 35(10). PMID: 17478523    Free PMC article.
Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8A1 and human ch13q34.
Martin C Abba, Victoria T Fabris, +6 authors, C Marcelo Aldaz.
Cancer Res, 2007 May 08; 67(9). PMID: 17483321    Free PMC article.
Towards a holistic, yet gene-centered analysis of gene expression profiles: a case study of human lung cancers.
Yuchun Guo, Gabriel S Eichler, +2 authors, Sui Huang.
J Biomed Biotechnol, 2007 May 10; 2006(5). PMID: 17489018    Free PMC article.
TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer.
Anita Langerød, Hongjuan Zhao, +6 authors, Stefanie S Jeffrey.
Breast Cancer Res, 2007 May 17; 9(3). PMID: 17504517    Free PMC article.
Highly Cited.
Molecular markers in patients with chronic wounds to guide surgical debridement.
Harold Brem, Olivera Stojadinovic, +6 authors, Marjana Tomic-Canic.
Mol Med, 2007 May 23; 13(1-2). PMID: 17515955    Free PMC article.
Phosphorylation of FAK, PI-3K, and impaired actin organization in CK-positive micrometastatic breast cancer cells.
Galatea Kallergi, Dimitris Mavroudis, Vassilis Georgoulias, Christos Stournaras.
Mol Med, 2007 May 23; 13(1-2). PMID: 17515959    Free PMC article.
RNA quality in frozen breast cancer samples and the influence on gene expression analysis--a comparison of three evaluation methods using microcapillary electrophoresis traces.
Carina Strand, Johan Enell, Ingrid Hedenfalk, Mårten Fernö.
BMC Mol Biol, 2007 May 24; 8. PMID: 17519006    Free PMC article.
Biweekly docetaxel and gemcitabine as neoadjuvant chemotherapy followed by adjuvant doxorubicin and cyclophosphamide therapy in stage II and III breast cancer patients: results of a phase II study.
L G Estévez, P Sánchez-Rovira, +11 authors, B San Antonio.
Clin Transl Oncol, 2007 May 26; 9(5). PMID: 17525042
Molecular concepts analysis links tumors, pathways, mechanisms, and drugs.
Daniel R Rhodes, Shanker Kalyana-Sundaram, +7 authors, Arul M Chinnaiyan.
Neoplasia, 2007 May 31; 9(5). PMID: 17534450    Free PMC article.
Low E2F1 transcript levels are a strong determinant of favorable breast cancer outcome.
Vincent Vuaroqueaux, Patrick Urban, +8 authors, Serenella Eppenberger-Castori.
Breast Cancer Res, 2007 May 31; 9(3). PMID: 17535433    Free PMC article.
Robust interlaboratory reproducibility of a gene expression signature measurement consistent with the needs of a new generation of diagnostic tools.
Robert A Ach, Arno Floore, +9 authors, Laura J Van't Veer.
BMC Genomics, 2007 Jun 08; 8. PMID: 17553173    Free PMC article.
A transcriptional program mediating entry into cellular quiescence.
Helen Liu, Adam S Adler, Eran Segal, Howard Y Chang.
PLoS Genet, 2007 Jun 15; 3(6). PMID: 17559306    Free PMC article.
An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells.
Stephan Duss, Sylvie André, +4 authors, Richard D Iggo.
Breast Cancer Res, 2007 Jun 19; 9(3). PMID: 17573968    Free PMC article.
New data on robustness of gene expression signatures in leukemia: comparison of three distinct total RNA preparation procedures.
Marta Campo Dell'Orto, Andrea Zangrando, +5 authors, Alexander Kohlmann.
BMC Genomics, 2007 Jun 26; 8. PMID: 17587440    Free PMC article.
Amplification patterns of three genomic regions predict distant recurrence in breast carcinoma.
Lisa M Davis, Cole Harris, +10 authors, John Hozier.
J Mol Diagn, 2007 Jun 27; 9(3). PMID: 17591932    Free PMC article.
A gene transcription signature associated with hormone independence in a subset of both breast and prostate cancers.
Chad J Creighton.
BMC Genomics, 2007 Jun 30; 8. PMID: 17598908    Free PMC article.
A perspective on DNA microarrays in pathology research and practice.
Jonathan R Pollack.
Am J Pathol, 2007 Jun 30; 171(2). PMID: 17600117    Free PMC article.
Saccharomyces cerevisiae signature genes for predicting nitrogen deficiency during alcoholic fermentation.
A Mendes-Ferreira, M del Olmo, +4 authors, J E Pérez-Ortín.
Appl Environ Microbiol, 2007 Jul 03; 73(16). PMID: 17601813    Free PMC article.
Strategy for encoding and comparison of gene expression signatures.
Yajun Yi, Chun Li, Clay Miller, Alfred L George.
Genome Biol, 2007 Jul 07; 8(7). PMID: 17612401    Free PMC article.
Favorable prognostic value of SOCS2 and IGF-I in breast cancer.
Michael C Haffner, Barbara Petridou, +5 authors, Wolfgang Doppler.
BMC Cancer, 2007 Jul 27; 7. PMID: 17651480    Free PMC article.
EGFR associated expression profiles vary with breast tumor subtype.
Katherine A Hoadley, Victor J Weigman, +8 authors, Charles M Perou.
BMC Genomics, 2007 Aug 01; 8. PMID: 17663798    Free PMC article.
Highly Cited.
An immune response gene expression module identifies a good prognosis subtype in estrogen receptor negative breast cancer.
Andrew E Teschendorff, Ahmad Miremadi, +2 authors, Carlos Caldas.
Genome Biol, 2007 Aug 09; 8(8). PMID: 17683518    Free PMC article.
Highly Cited.
Elucidating the altered transcriptional programs in breast cancer using independent component analysis.
Andrew E Teschendorff, Michel Journée, +2 authors, Carlos Caldas.
PLoS Comput Biol, 2007 Aug 22; 3(8). PMID: 17708679    Free PMC article.
Quantification of the impact of feature selection on the variance of cross-validation error estimation.
Yufei Xiao, Jianping Hua, Edward R Dougherty.
EURASIP J Bioinform Syst Biol, 2007 Aug 24;. PMID: 17713587    Free PMC article.
Recent advances on the molecular mechanisms involved in the drug resistance of cancer cells and novel targeting therapies.
M Mimeault, R Hauke, S K Batra.
Clin Pharmacol Ther, 2007 Sep 06; 83(5). PMID: 17786164    Free PMC article.
Review.
The LeFE algorithm: embracing the complexity of gene expression in the interpretation of microarray data.
Gabriel S Eichler, Mark Reimers, David Kane, John N Weinstein.
Genome Biol, 2007 Sep 12; 8(9). PMID: 17845722    Free PMC article.
Strategic plans to promote head and neck cancer translational research within the radiation therapy oncology group: a report from the translational research program.
Christine H Chung, Stuart Wong, +4 authors, Quynh-Thu Le.
Int J Radiat Oncol Biol Phys, 2007 Oct 18; 69(2 Suppl). PMID: 17848300    Free PMC article.
A Marfan syndrome gene expression phenotype in cultured skin fibroblasts.
Zizhen Yao, Jochen C Jaeger, +6 authors, Eileen R Mulvihill.
BMC Genomics, 2007 Sep 14; 8. PMID: 17850668    Free PMC article.
Breast cancer molecular signatures as determined by SAGE: correlation with lymph node status.
Martín C Abba, Hongxia Sun, +8 authors, C Marcelo Aldaz.
Mol Cancer Res, 2007 Sep 15; 5(9). PMID: 17855657    Free PMC article.
Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer.
Martin Buess, Dimitry S A Nuyten, +3 authors, Patrick O Brown.
Genome Biol, 2007 Sep 18; 8(9). PMID: 17868458    Free PMC article.
Integrated analysis of independent gene expression microarray datasets improves the predictability of breast cancer outcome.
Zhe Zhang, Dechang Chen, David A Fenstermacher.
BMC Genomics, 2007 Sep 22; 8. PMID: 17883867    Free PMC article.
Pathway analysis of gene signatures predicting metastasis of node-negative primary breast cancer.
Jack X Yu, Anieta M Sieuwerts, +5 authors, John A Foekens.
BMC Cancer, 2007 Sep 27; 7. PMID: 17894856    Free PMC article.
Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas.
Bas Kreike, Marieke van Kouwenhove, +4 authors, Marc J van de Vijver.
Breast Cancer Res, 2007 Oct 04; 9(5). PMID: 17910759    Free PMC article.
Highly Cited.
Femara and the future: tailoring treatment and combination therapies with Femara.
Matthew Ellis, Cynthia Ma.
Breast Cancer Res Treat, 2007 Nov 21; 105 Suppl 1. PMID: 17912640    Free PMC article.
Review.
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype.
Cherie Blenkiron, Leonard D Goldstein, +10 authors, Eric A Miska.
Genome Biol, 2007 Oct 10; 8(10). PMID: 17922911    Free PMC article.
Highly Cited.
High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer.
Suet F Chin, Andrew E Teschendorff, +13 authors, Carlos Caldas.
Genome Biol, 2007 Oct 11; 8(10). PMID: 17925008    Free PMC article.
Highly Cited.
Network-based classification of breast cancer metastasis.
Han-Yu Chuang, Eunjung Lee, +2 authors, Trey Ideker.
Mol Syst Biol, 2007 Oct 18; 3. PMID: 17940530    Free PMC article.
Highly Cited.
Module-based outcome prediction using breast cancer compendia.
Martin H van Vliet, Christiaan N Klijn, Lodewyk F A Wessels, Marcel J T Reinders.
PLoS One, 2007 Oct 18; 2(10). PMID: 17940611    Free PMC article.
Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets.
Michael Gormley, William Dampier, +2 authors, Aydin Tozeren.
BMC Bioinformatics, 2007 Oct 30; 8. PMID: 17963508    Free PMC article.
SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets.
Carmen Lai, Hugo M Horlings, +4 authors, Marcel J T Reinders.
BMC Bioinformatics, 2007 Nov 01; 8. PMID: 17971227    Free PMC article.
New concepts in breast cancer metastasis: tumor initiating cells and the microenvironment.
Jonathan P Sleeman, Natascha Cremers.
Clin Exp Metastasis, 2007 Nov 01; 24(8). PMID: 17972145
Review.
Gene arrays for diagnosis, prognosis and treatment of breast cancer metastasis.
Keltouma Driouch, Thomas Landemaine, +2 authors, Rosette Lidereau.
Clin Exp Metastasis, 2007 Nov 02; 24(8). PMID: 17973194
Review.
Genomic signatures of breast cancer metastasis.
V Urquidi, S Goodison.
Cytogenet Genome Res, 2007 Nov 15; 118(2-4). PMID: 18000362    Free PMC article.
Systems biology and cancer stem cells.
Nathan D Price, Greg Foltz, +2 authors, Qiang Tian.
J Cell Mol Med, 2007 Nov 23; 12(1). PMID: 18031300    Free PMC article.
Review.
International Web-based consultation on priorities for translational breast cancer research.
Mitch Dowsett, Aron Goldhirsch, +3 authors, Giuseppe Viale.
Breast Cancer Res, 2007 Nov 24; 9(6). PMID: 18034879    Free PMC article.
Being 40 or younger is an independent risk factor for relapse in operable breast cancer patients: the Saudi Arabia experience.
Naser Elkum, Said Dermime, +7 authors, Taher Al-Tweigeri.
BMC Cancer, 2007 Dec 07; 7. PMID: 18053234    Free PMC article.
Use of the Oncotype DX 21-gene assay to guide adjuvant decision making in early-stage breast cancer.
Alison K Conlin, Andrew D Seidman.
Mol Diagn Ther, 2007 Dec 15; 11(6). PMID: 18078353
Review.
Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis.
Nigel P S Crawford, Xiaolan Qian, +10 authors, Kent W Hunter.
PLoS Genet, 2007 Dec 18; 3(11). PMID: 18081427    Free PMC article.
Literature Lab: a method of automated literature interrogation to infer biology from microarray analysis.
Phillip G Febbo, Mike G Mulligan, +5 authors, Stephen C Taylor.
BMC Genomics, 2007 Dec 20; 8. PMID: 18088408    Free PMC article.
Complementary hierarchical clustering.
Gen Nowak, Robert Tibshirani.
Biostatistics, 2007 Dec 21; 9(3). PMID: 18093965    Free PMC article.
Validation and quality control of protein microarray-based analytical methods.
Larry J Kricka, Stephen R Master.
Mol Biotechnol, 2007 Dec 21; 38(1). PMID: 18095188
Review.
The properties of high-dimensional data spaces: implications for exploring gene and protein expression data.
Robert Clarke, Habtom W Ressom, +4 authors, Yue Wang.
Nat Rev Cancer, 2007 Dec 22; 8(1). PMID: 18097463    Free PMC article.
Highly Cited. Review.
A highly sensitive and specific system for large-scale gene expression profiling.
Guohong Hu, Qifeng Yang, +4 authors, Honghua Li.
BMC Genomics, 2008 Jan 12; 9. PMID: 18186939    Free PMC article.
Can clinically relevant prognostic subsets of breast cancer patients with four or more involved axillary lymph nodes be identified through immunohistochemical biomarkers? A tissue microarray feasibility study.
Simon J Crabb, Chris D Bajdik, +4 authors, Karen A Gelmon.
Breast Cancer Res, 2008 Jan 16; 10(1). PMID: 18194560    Free PMC article.
Signature Evaluation Tool (SET): a Java-based tool to evaluate and visualize the sample discrimination abilities of gene expression signatures.
Chih-Hung Jen, Tsun-Po Yang, +4 authors, Hsei-Wei Wang.
BMC Bioinformatics, 2008 Jan 29; 9. PMID: 18221568    Free PMC article.
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation.
David D Smith, Pål Saetrom, +4 authors, Garrett P Larson.
BMC Bioinformatics, 2008 Jan 30; 9. PMID: 18226260    Free PMC article.
A transcriptional fingerprint of estrogen in human breast cancer predicts patient survival.
Jianjun Yu, Jindan Yu, +5 authors, Marc E Lippman.
Neoplasia, 2008 Jan 31; 10(1). PMID: 18231641    Free PMC article.
Response projected clustering for direct association with physiological and clinical response data.
Sung-Gon Yi, Taesung Park, Jae K Lee.
BMC Bioinformatics, 2008 Feb 02; 9. PMID: 18237428    Free PMC article.
A first-generation multiplex biomarker analysis of urine for the early detection of prostate cancer.
Bharathi Laxman, David S Morris, +8 authors, Arul M Chinnaiyan.
Cancer Res, 2008 Feb 05; 68(3). PMID: 18245462    Free PMC article.
Highly Cited.
A procedure for tissue freezing and processing applicable to both intra-operative frozen section diagnosis and tissue banking in surgical pathology.
Susanne Steu, Maya Baucamp, +5 authors, Peter Schraml.
Virchows Arch, 2008 Feb 07; 452(3). PMID: 18253747
Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1.
Akane Kawamura, Isaac Westwood, +5 authors, Edith Sim.
Biochem Pharmacol, 2008 Feb 19; 75(7). PMID: 18280460    Free PMC article.
Decorrelation of the true and estimated classifier errors in high-dimensional settings.
Blaise Hanczar, Jianping Hua, Edward R Dougherty.
EURASIP J Bioinform Syst Biol, 2008 Feb 22;. PMID: 18288255    Free PMC article.
The Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival.
Nigel P S Crawford, Renard C Walker, +3 authors, Kent W Hunter.
Clin Exp Metastasis, 2008 Feb 28; 25(4). PMID: 18301994    Free PMC article.
Merging microarray data from separate breast cancer studies provides a robust prognostic test.
Lei Xu, Aik Choon Tan, Raimond L Winslow, Donald Geman.
BMC Bioinformatics, 2008 Feb 29; 9. PMID: 18304324    Free PMC article.
Update of evidence in chemotherapy for breast cancer.
Hiroyasu Yamashiro, Masakazu Toi.
Int J Clin Oncol, 2008 Mar 01; 13(1). PMID: 18307012
Review.
Comparing the characteristics of gene expression profiles derived by univariate and multivariate classification methods.
Manuela Zucknick, Sylvia Richardson, Euan A Stronach.
Stat Appl Genet Mol Biol, 2008 Mar 04; 7(1). PMID: 18312212    Free PMC article.
Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo.
Bushra Ateeq, Alexander Unterberger, Moshe Szyf, Shafaat A Rabbani.
Neoplasia, 2008 Mar 06; 10(3). PMID: 18320071    Free PMC article.
Intestinal adenomagenesis involves core molecular signatures of the epithelial-mesenchymal transition.
Xiaodi Chen, Richard B Halberg, Ryan P Burch, William F Dove.
J Mol Histol, 2008 Mar 11; 39(3). PMID: 18327651    Free PMC article.
Staging systems in hepatocellular carcinoma.
Fernando Pons, Maria Varela, Josep M Llovet.
HPB (Oxford), 2008 Mar 12; 7(1). PMID: 18333159    Free PMC article.
Carbonic anhydrase IX and response to postmastectomy radiotherapy in high-risk breast cancer: a subgroup analysis of the DBCG82 b and c trials.
Marianne Kyndi, Flemming B Sørensen, +5 authors, Danish Breast Cancer Cooperative Group.
Breast Cancer Res, 2008 Mar 22; 10(2). PMID: 18355402    Free PMC article.
Indirect genomic effects on survival from gene expression data.
Egil Ferkingstad, Arnoldo Frigessi, Heidi Lyng.
Genome Biol, 2008 Mar 25; 9(3). PMID: 18358079    Free PMC article.
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription.
Mathieu Lupien, Jérôme Eeckhoute, +6 authors, Myles Brown.
Cell, 2008 Mar 25; 132(6). PMID: 18358809    Free PMC article.
Highly Cited.
Renal cell carcinoma and the use of sorafenib.
James Mg Larkin, Tim Eisen.
Ther Clin Risk Manag, 2008 Mar 25; 2(1). PMID: 18360584    Free PMC article.
The estrogen and c-Myc target gene HSPC111 is over-expressed in breast cancer and associated with poor patient outcome.
Alison J Butt, C Marcelo Sergio, +8 authors, Elizabeth A Musgrove.
Breast Cancer Res, 2008 Apr 01; 10(2). PMID: 18373870    Free PMC article.
Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients.
Aman Russom, Palaniappan Sethu, +17 authors, Inflammation and Host Response to Injury Large Scale Collaborative Research Program.
Clin Chem, 2008 Apr 01; 54(5). PMID: 18375483    Free PMC article.
Differentiating proteomic biomarkers in breast cancer by laser capture microdissection and MALDI MS.
Melinda E Sanders, Eduardo C Dias, +7 authors, Richard M Caprioli.
J Proteome Res, 2008 Apr 05; 7(4). PMID: 18386930    Free PMC article.
TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4.
David Padua, Xiang H-F Zhang, +4 authors, Joan Massagué.
Cell, 2008 Apr 09; 133(1). PMID: 18394990    Free PMC article.
Highly Cited.
Module map of stem cell genes guides creation of epithelial cancer stem cells.
David J Wong, Helen Liu, +3 authors, Howard Y Chang.
Cell Stem Cell, 2008 Apr 10; 2(4). PMID: 18397753    Free PMC article.
Highly Cited.
Promoter hypermethylation in sentinel lymph nodes as a marker for breast cancer recurrence.
Hetty E Carraway, Shelun Wang, +8 authors, Julie R Lange.
Breast Cancer Res Treat, 2008 Apr 12; 114(2). PMID: 18404369    Free PMC article.
Estrogen-mediated downregulation of CD24 in breast cancer cells.
Benny Abraham Kaipparettu, Simeen Malik, +11 authors, Hiltrud Brauch.
Int J Cancer, 2008 Apr 12; 123(1). PMID: 18404683    Free PMC article.
The fibromatosis signature defines a robust stromal response in breast carcinoma.
Andrew H Beck, Inigo Espinosa, +2 authors, Robert B West.
Lab Invest, 2008 Apr 17; 88(6). PMID: 18414401    Free PMC article.
Genomic analysis of estrogen cascade reveals histone variant H2A.Z associated with breast cancer progression.
Sujun Hua, Caleb B Kallen, +11 authors, Kevin P White.
Mol Syst Biol, 2008 Apr 17; 4. PMID: 18414489    Free PMC article.
A gene sets approach for identifying prognostic gene signatures for outcome prediction.
Seon-Young Kim, Yong Sung Kim.
BMC Genomics, 2008 Apr 18; 9. PMID: 18416850    Free PMC article.
Predictive gene lists for breast cancer prognosis: a topographic visualisation study.
Mingmanas Sivaraksa, David Lowe.
BMC Med Genomics, 2008 Apr 19; 1. PMID: 18419801    Free PMC article.
Molecular profiles of progesterone receptor loss in human breast tumors.
Chad J Creighton, C Kent Osborne, +10 authors, Rachel Schiff.
Breast Cancer Res Treat, 2008 Apr 22; 114(2). PMID: 18425577    Free PMC article.
Bromodomain 4 activation predicts breast cancer survival.
Nigel P S Crawford, Jude Alsarraj, +6 authors, Kent W Hunter.
Proc Natl Acad Sci U S A, 2008 Apr 23; 105(17). PMID: 18427120    Free PMC article.
Gene expression profiling in primary breast cancer distinguishes patients developing local recurrence after breast-conservation surgery, with or without postoperative radiotherapy.
Emma Niméus-Malmström, Morten Krogh, +8 authors, Mårten Fernö.
Breast Cancer Res, 2008 Apr 24; 10(2). PMID: 18430221    Free PMC article.
The T7-primer is a source of experimental bias and introduces variability between microarray platforms.
Ron M Kerkhoven, Daoud Sie, +4 authors, Arno Velds.
PLoS One, 2008 Apr 24; 3(4). PMID: 18431470    Free PMC article.
Cell cycle correlated genes dictate the prognostic power of breast cancer gene lists.
Jonathan D Mosley, Ruth A Keri.
BMC Med Genomics, 2008 Apr 29; 1. PMID: 18439262    Free PMC article.
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors.
Ittai Ben-Porath, Matthew W Thomson, +4 authors, Robert A Weinberg.
Nat Genet, 2008 Apr 30; 40(5). PMID: 18443585    Free PMC article.
Highly Cited.
Neutrophil gelatinase-associated lipocalin: new paths for an old shuttle.
Prasad Devarajan.
Cancer Ther, 2008 May 02; 5(B). PMID: 18449360    Free PMC article.
Mechanisms of malignant progression.
Robert A Weinberg.
Carcinogenesis, 2008 May 06; 29(6). PMID: 18453542    Free PMC article.
Review.
Unraveling the microenvironmental influences on the normal mammary gland and breast cancer.
Britta Weigelt, Mina J Bissell.
Semin Cancer Biol, 2008 May 06; 18(5). PMID: 18455428    Free PMC article.
Highly Cited. Review.
Analysis of the MammaPrint breast cancer assay in a predominantly postmenopausal cohort.
Ben S Wittner, Dennis C Sgroi, +9 authors, Sridhar Ramaswamy.
Clin Cancer Res, 2008 May 17; 14(10). PMID: 18483364    Free PMC article.
Which is better: holdout or full-sample classifier design?
Marcel Brun, Qian Xu, Edward R Dougherty.
EURASIP J Bioinform Syst Biol, 2008 May 17;. PMID: 18483613    Free PMC article.
The fibroblast growth factor-inducible 14 receptor is highly expressed in HER2-positive breast tumors and regulates breast cancer cell invasive capacity.
Amanda L Willis, Nhan L Tran, +9 authors, Heather E Cunliffe.
Mol Cancer Res, 2008 May 29; 6(5). PMID: 18505918    Free PMC article.
Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis.
Timothy A Chan, Sabine Glockner, +8 authors, Stephen B Baylin.
PLoS Med, 2008 May 30; 5(5). PMID: 18507500    Free PMC article.
Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort.
Elizabeth M Azzato, Kristy E Driver, +7 authors, Paul D P Pharoah.
Breast Cancer Res, 2008 May 30; 10(3). PMID: 18507837    Free PMC article.
Surface-enhanced laser desorption/ionization time-of-flight proteomic profiling of breast carcinomas identifies clinicopathologically relevant groups of patients similar to previously defined clusters from cDNA expression.
Kristyna Brozkova, Eva Budinska, +6 authors, Rudolf Nenutil.
Breast Cancer Res, 2008 May 31; 10(3). PMID: 18510725    Free PMC article.
Molecular imaging of metastatic potential.
Paul T Winnard, Arvind P Pathak, +3 authors, Martin G Pomper.
J Nucl Med, 2008 Jul 01; 49 Suppl 2. PMID: 18523068    Free PMC article.
Review.
Linking molecular classification of hepatocellular carcinoma and personalized medicine: preliminary steps.
Augusto Villanueva, Sara Toffanin, Josep M Llovet.
Curr Opin Oncol, 2008 Jun 06; 20(4). PMID: 18525342    Free PMC article.
Review.
Breast tumor metastasis: analysis via proteomic profiling.
Steve Goodison, Virginia Urquidi.
Expert Rev Proteomics, 2008 Jun 06; 5(3). PMID: 18532913    Free PMC article.
Review.
The Nottingham prognostic index for invasive carcinoma of the breast.
Andrew H S Lee, Ian O Ellis.
Pathol Oncol Res, 2008 Jun 11; 14(2). PMID: 18543079
Review.
Systemic endocrine instigation of indolent tumor growth requires osteopontin.
Sandra S McAllister, Ann M Gifford, +8 authors, Robert A Weinberg.
Cell, 2008 Jun 17; 133(6). PMID: 18555776    Free PMC article.
Highly Cited.
Development of a clinically feasible molecular assay to predict recurrence of stage II colon cancer.
Yuqiu Jiang, Graham Casey, +9 authors, Yixin Wang.
J Mol Diagn, 2008 Jun 17; 10(4). PMID: 18556775    Free PMC article.
Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors.
Anita L Bane, Dushanthi Pinnaduwage, +5 authors, Irene L Andrulis.
Breast Cancer Res Treat, 2008 Jun 20; 117(1). PMID: 18563556    Free PMC article.
In praise of arrays.
Lihua Ying, Minnie Sarwal.
Pediatr Nephrol, 2008 Jun 24; 24(9). PMID: 18568367    Free PMC article.
Review.
Proteomic analysis of amniotic fluid to identify women with preterm labor and intra-amniotic inflammation/infection: the use of a novel computational method to analyze mass spectrometric profiling.
Roberto Romero, Jimmy Espinoza, +8 authors, Sonia S Hassan.
J Matern Fetal Neonatal Med, 2008 Jun 24; 21(6). PMID: 18570116    Free PMC article.
Regularized estimation for the accelerated failure time model.
T Cai, J Huang, L Tian.
Biometrics, 2008 Jun 25; 65(2). PMID: 18573133    Free PMC article.
Pathway analysis reveals functional convergence of gene expression profiles in breast cancer.
Ronglai Shen, Arul M Chinnaiyan, Debashis Ghosh.
BMC Med Genomics, 2008 Jul 01; 1. PMID: 18588682    Free PMC article.
An expression signature of estrogen-regulated genes predicts disease-free survival in tamoxifen-treated patients better than progesterone receptor status.
Marc E Lippman, James M Rae, Arul M Chinnaiyan.
Trans Am Clin Climatol Assoc, 2008 Jul 04; 119. PMID: 18596862    Free PMC article.
KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis.
Goutham Narla, Analisa DiFeo, +11 authors, John A Martignetti.
J Clin Invest, 2008 Jul 04; 118(8). PMID: 18596922    Free PMC article.
Tumor slices as a model to evaluate doxorubicin in vitro treatment and expression of trios of genes PRSS11, MTSS1, CLPTM1 and PRSS11, MTSS1, SMYD2 in canine mammary gland cancer.
Renata A Sobral, Suzana T Honda, +4 authors, Maria Aparecida A K Folgueira.
Acta Vet Scand, 2008 Jul 08; 50. PMID: 18601734    Free PMC article.
National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines for use of tumor markers in clinical practice: quality requirements.
Catharine M Sturgeon, Barry R Hoffman, +11 authors, National Academy of Clinical Biochemistry.
Clin Chem, 2008 Jul 09; 54(8). PMID: 18606634    Free PMC article.
Management of breast cancer--Part II.
Nicholas C Turner, Alison L Jones.
BMJ, 2008 Jul 16; 337. PMID: 18621762    Free PMC article.
Review.
Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab.
Shizhen Emily Wang, Bin Xiang, +5 authors, Carlos L Arteaga.
Mol Cell Biol, 2008 Jul 16; 28(18). PMID: 18625725    Free PMC article.
A comparative study of survival models for breast cancer prognostication based on microarray data: does a single gene beat them all?
B Haibe-Kains, C Desmedt, C Sotiriou, G Bontempi.
Bioinformatics, 2008 Jul 19; 24(19). PMID: 18635567    Free PMC article.
Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays.
David I Rodenhiser, Joseph Andrews, +4 authors, Ann F Chambers.
Breast Cancer Res, 2008 Jul 22; 10(4). PMID: 18638373    Free PMC article.
Molecular profiling including epidermal growth factor receptor and p21 expression in high-risk breast cancer patients as indicators of outcome.
G Somlo, P Chu, +5 authors, P Danenberg.
Ann Oncol, 2008 Jul 22; 19(11). PMID: 18641005    Free PMC article.
Molecular signatures of metastasis in head and neck cancer.
Stefano Colella, Kristy L Richards, +5 authors, Ralf Krahe.
Head Neck, 2008 Jul 22; 30(10). PMID: 18642293    Free PMC article.
Validation of computational methods in genomics.
Edward R Doughtery, Hua Jianping, Michael L Bittner.
Curr Genomics, 2008 Jul 23; 8(1). PMID: 18645624    Free PMC article.
PRAME expression and clinical outcome of breast cancer.
M T Epping, A A M Hart, +2 authors, R Bernards.
Br J Cancer, 2008 Jul 24; 99(3). PMID: 18648365    Free PMC article.
Mouse modifier genes in mammary tumorigenesis and metastasis.
Scott F Winter, Kent W Hunter.
J Mammary Gland Biol Neoplasia, 2008 Jul 29; 13(3). PMID: 18661105
Review.
Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures.
Pratyaksha Wirapati, Christos Sotiriou, +10 authors, Mauro Delorenzi.
Breast Cancer Res, 2008 Jul 30; 10(4). PMID: 18662380    Free PMC article.
Highly Cited.
Prognostic utility of the 21-gene assay in hormone receptor-positive operable breast cancer compared with classical clinicopathologic features.
Lori J Goldstein, Robert Gray, +12 authors, Joseph A Sparano.
J Clin Oncol, 2008 Aug 06; 26(25). PMID: 18678838    Free PMC article.
Highly Cited.
RNA expression analysis from formalin fixed paraffin embedded tissues.
Susan M Farragher, Austin Tanney, Richard D Kennedy, D Paul Harkin.
Histochem Cell Biol, 2008 Aug 06; 130(3). PMID: 18679706
Review.
Exon 20 PIK3CA mutations decreases survival in aggressive (HER-2 positive) breast carcinomas.
Enrique Lerma, Lluis Catasus, +5 authors, Jaime Prat.
Virchows Arch, 2008 Aug 06; 453(2). PMID: 18679714
Pooling breast cancer datasets has a synergetic effect on classification performance and improves signature stability.
Martin H van Vliet, Fabien Reyal, +3 authors, Lodewyk F A Wessels.
BMC Genomics, 2008 Aug 08; 9. PMID: 18684329    Free PMC article.
Molecular detection of PPAR gamma rearrangements and thyroid carcinoma in preoperative fine-needle aspiration biopsies.
Christopher A French, Jonathan A Fletcher, +3 authors, Todd G Kroll.
Endocr Pathol, 2008 Aug 09; 19(3). PMID: 18688583
A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospects.
Bas J Wouters, Bob Löwenberg, Ruud Delwel.
Blood, 2008 Aug 16; 113(2). PMID: 18703705    Free PMC article.
Review.
The relevance of mouse models to understanding the development and progression of human breast cancer.
D Craig Allred, Daniel Medina.
J Mammary Gland Biol Neoplasia, 2008 Aug 16; 13(3). PMID: 18704660
Review.
Common integration sites for MMTV in viral induced mouse mammary tumors.
Robert Callahan, Gilbert H Smith.
J Mammary Gland Biol Neoplasia, 2008 Aug 19; 13(3). PMID: 18709449    Free PMC article.
Review.
Gene panel model predictive of outcome in men at high-risk of systemic progression and death from prostate cancer after radical retropubic prostatectomy.
John C Cheville, R Jeffrey Karnes, +10 authors, George Vasmatzis.
J Clin Oncol, 2008 Aug 20; 26(24). PMID: 18711181    Free PMC article.
Prognostic breast cancer signature identified from 3D culture model accurately predicts clinical outcome across independent datasets.
Katherine J Martin, Denis R Patrick, Mina J Bissell, Marcia V Fournier.
PLoS One, 2008 Aug 21; 3(8). PMID: 18714348    Free PMC article.
Highly Cited.
Combining biological gene expression signatures in predicting outcome in breast cancer: An alternative to supervised classification.
Dimitry S A Nuyten, Trevor Hastie, +2 authors, Marc J van de Vijver.
Eur J Cancer, 2008 Aug 22; 44(15). PMID: 18715778    Free PMC article.
Comparison of prognostic gene expression signatures for breast cancer.
Benjamin Haibe-Kains, Christine Desmedt, +6 authors, Christos Sotiriou.
BMC Genomics, 2008 Aug 23; 9. PMID: 18717985    Free PMC article.
A robust classifier of high predictive value to identify good prognosis patients in ER-negative breast cancer.
Andrew E Teschendorff, Carlos Caldas.
Breast Cancer Res, 2008 Aug 30; 10(4). PMID: 18755024    Free PMC article.
Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer.
Omar Khalid, Sanjeev K Baniwal, +5 authors, Baruch Frenkel.
Endocrinology, 2008 Aug 30; 149(12). PMID: 18755791    Free PMC article.
Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis.
Chad J Creighton, Angelo Casa, +5 authors, Adrian V Lee.
J Clin Oncol, 2008 Sep 02; 26(25). PMID: 18757322    Free PMC article.
Highly Cited.
Key issues in conducting a meta-analysis of gene expression microarray datasets.
Adaikalavan Ramasamy, Adrian Mondry, Chris C Holmes, Douglas G Altman.
PLoS Med, 2008 Sep 05; 5(9). PMID: 18767902    Free PMC article.
Highly Cited. Review.
Germline polymorphisms as modulators of cancer phenotypes.
Patrick Tan.
BMC Med, 2008 Sep 10; 6. PMID: 18778478    Free PMC article.
Review.
Gene expression variation to predict 10-year survival in lymph-node-negative breast cancer.
Elin Karlsson, Ulla Delle, +4 authors, Khalil Helou.
BMC Cancer, 2008 Sep 10; 8. PMID: 18778486    Free PMC article.
A predictive risk probability approach for microarray data with survival as an endpoint.
Dung-Tsa Chen, Michael J Schell, +3 authors, Timothy Yeatman.
J Biopharm Stat, 2008 Sep 11; 18(5). PMID: 18781520    Free PMC article.
The functional loss of the retinoblastoma tumour suppressor is a common event in basal-like and luminal B breast carcinomas.
Jason I Herschkowitz, Xiaping He, Cheng Fan, Charles M Perou.
Breast Cancer Res, 2008 Sep 11; 10(5). PMID: 18782450    Free PMC article.
Highly Cited.
Identification of a gene signature in cell cycle pathway for breast cancer prognosis using gene expression profiling data.
Jiangang Liu, Andrew Campen, +6 authors, Shuyu Li.
BMC Med Genomics, 2008 Sep 13; 1. PMID: 18786252    Free PMC article.
Cytochrome P450 2D6 and homeobox 13/interleukin-17B receptor: combining inherited and tumor gene markers for prediction of tamoxifen resistance.
Matthew P Goetz, Vera J Suman, +12 authors, James N Ingle.
Clin Cancer Res, 2008 Sep 17; 14(18). PMID: 18794098    Free PMC article.
Development of resistance to targeted therapies transforms the clinically associated molecular profile subtype of breast tumor xenografts.
Chad J Creighton, Suleiman Massarweh, +6 authors, Rachel Schiff.
Cancer Res, 2008 Sep 17; 68(18). PMID: 18794137    Free PMC article.
Sickness absence and return to work rates in women with breast cancer.
Corné A M Roelen, Petra C Koopmans, +2 authors, Johan W Groothoff.
Int Arch Occup Environ Health, 2008 Sep 17; 82(4). PMID: 18795317
Integrative bioinformatics analysis of transcriptional regulatory programs in breast cancer cells.
Atsushi Niida, Andrew D Smith, +4 authors, Tetsu Akiyama.
BMC Bioinformatics, 2008 Oct 01; 9. PMID: 18823535    Free PMC article.
Gene expression profiling of liver metastases from colorectal cancer as potential basis for treatment choice.
M A Pantaleo, A Astolfi, +8 authors, G Biasco.
Br J Cancer, 2008 Oct 02; 99(10). PMID: 18827815    Free PMC article.
Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis.
A Takeno, I Takemasa, +6 authors, M Monden.
Br J Cancer, 2008 Oct 02; 99(8). PMID: 18827816    Free PMC article.
Unlocking the power of cross-species genomic analyses: identification of evolutionarily conserved breast cancer networks and validation of preclinical models.
Christina N Bennett, Jeffrey E Green.
Breast Cancer Res, 2008 Oct 03; 10(5). PMID: 18828875    Free PMC article.
Review.
A method for analyzing censored survival phenotype with gene expression data.
Tongtong Wu, Wei Sun, +2 authors, Ker-Chau Li.
BMC Bioinformatics, 2008 Oct 08; 9. PMID: 18837994    Free PMC article.
Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer.
Paolo P Provenzano, David R Inman, +2 authors, Patricia J Keely.
Am J Pathol, 2008 Oct 11; 173(5). PMID: 18845837    Free PMC article.
Towards preventive medicine. High-throughput methods from molecular biology are about to change daily clinical practice.
Hrvojka Bosnjak, Kresimir Pavelic, Sandra Kraljevic Pavelic.
EMBO Rep, 2008 Oct 11; 9(11). PMID: 18846103    Free PMC article.
The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer.
Marissa E Nolan, Victoria Aranda, +4 authors, Senthil K Muthuswamy.
Cancer Res, 2008 Oct 17; 68(20). PMID: 18922891    Free PMC article.
From evidence-based medicine to genomic medicine.
Dhavendra Kumar.
Genomic Med, 2008 Oct 17; 1(3-4). PMID: 18923934    Free PMC article.
Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes.
Golareh Habibi, Samuel Leung, +7 authors, Sandra E Dunn.
Breast Cancer Res, 2008 Oct 18; 10(5). PMID: 18925950    Free PMC article.
A candidate molecular signature associated with tamoxifen failure in primary breast cancer.
Julie A Vendrell, Katherine E Robertson, +10 authors, Pascale A Cohen.
Breast Cancer Res, 2008 Oct 22; 10(5). PMID: 18928543    Free PMC article.
Gene expression profiling of breast cancer.
Ting Bao, Nancy E Davidson.
Adv Surg, 2008 Oct 29; 42. PMID: 18953822    Free PMC article.
Review.
Robust prognostic value of a knowledge-based proliferation signature across large patient microarray studies spanning different cancer types.
M H W Starmans, B Krishnapuram, +8 authors, P Lambin.
Br J Cancer, 2008 Nov 06; 99(11). PMID: 18985037    Free PMC article.
Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer.
Charles Swanton, Zoltan Szallasi, James D Brenton, Julian Downward.
Breast Cancer Res, 2008 Nov 07; 10(5). PMID: 18986507    Free PMC article.
Review.
Inferring pathway activity toward precise disease classification.
Eunjung Lee, Han-Yu Chuang, +2 authors, Doheon Lee.
PLoS Comput Biol, 2008 Nov 08; 4(11). PMID: 18989396    Free PMC article.
Highly Cited.
An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer.
Ralph R Weichselbaum, Hemant Ishwaran, +12 authors, Andy J Minn.
Proc Natl Acad Sci U S A, 2008 Nov 13; 105(47). PMID: 19001271    Free PMC article.
Highly Cited.
A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer.
Fabien Reyal, Martin H van Vliet, +10 authors, Lodewyk F A Wessels.
Breast Cancer Res, 2008 Nov 19; 10(6). PMID: 19014521    Free PMC article.
Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature.
Andrew Tutt, Alice Wang, +21 authors, Fred Waldman.
BMC Cancer, 2008 Nov 26; 8. PMID: 19025599    Free PMC article.
A functional Notch-survivin gene signature in basal breast cancer.
Connie W Lee, Karl Simin, +5 authors, Dario C Altieri.
Breast Cancer Res, 2008 Nov 26; 10(6). PMID: 19025652    Free PMC article.
In vitro and in vivo analysis of B-Myb in basal-like breast cancer.
A R Thorner, K A Hoadley, +3 authors, C M Perou.
Oncogene, 2008 Dec 02; 28(5). PMID: 19043454    Free PMC article.
Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor.
Neeraj K Saxena, LaTonia Taliaferro-Smith, +4 authors, Dipali Sharma.
Cancer Res, 2008 Dec 03; 68(23). PMID: 19047149    Free PMC article.
BAG-1 predicts patient outcome and tamoxifen responsiveness in ER-positive invasive ductal carcinoma of the breast.
E K A Millar, L R Anderson, +9 authors, A J Butt.
Br J Cancer, 2008 Dec 11; 100(1). PMID: 19066611    Free PMC article.
Biological processes, properties and molecular wiring diagrams of candidate low-penetrance breast cancer susceptibility genes.
Núria Bonifaci, Antoni Berenguer, +5 authors, Miguel Angel Pujana.
BMC Med Genomics, 2008 Dec 20; 1. PMID: 19094230    Free PMC article.
Clinical impact of high-throughput gene expression studies in lung cancer.
Jennifer Beane, Avrum Spira, Marc E Lenburg.
J Thorac Oncol, 2008 Dec 20; 4(1). PMID: 19096318    Free PMC article.
Review.
EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer.
Alexandra M Pietersen, Hugo M Horlings, +7 authors, Maarten van Lohuizen.
Breast Cancer Res, 2008 Dec 23; 10(6). PMID: 19099573    Free PMC article.
The gene expression signature of genomic instability in breast cancer is an independent predictor of clinical outcome.
Jens K Habermann, Jana Doering, +12 authors, Thomas Ried.
Int J Cancer, 2008 Dec 23; 124(7). PMID: 19101988    Free PMC article.
Haptoglobin phenotype is not a predictor of recurrence free survival in high-risk primary breast cancer patients.
Marie-Christine W Gast, Harm van Tinteren, +10 authors, Jos H Beijnen.
BMC Cancer, 2008 Dec 26; 8. PMID: 19108738    Free PMC article.
Molecular basis of metastasis.
Anne C Chiang, Joan Massagué.
N Engl J Med, 2008 Dec 26; 359(26). PMID: 19109576    Free PMC article.
Highly Cited. Review.
MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer.
Guohong Hu, Robert A Chong, +7 authors, Yibin Kang.
Cancer Cell, 2008 Dec 30; 15(1). PMID: 19111877    Free PMC article.
Highly Cited.
The development of a mini-array for estimating the disease state of gastric adenocarcinoma by array CGH.
Tomoko Furuya, Tetsuji Uchiyama, +6 authors, Kohsuke Sasaki.
BMC Cancer, 2009 Jan 01; 8. PMID: 19115996    Free PMC article.
Gene expression meta-analysis identifies metastatic pathways and transcription factors in breast cancer.
Mads Thomassen, Qihua Tan, Torben A Kruse.
BMC Cancer, 2009 Jan 01; 8. PMID: 19116006    Free PMC article.
The origins of breast cancer prognostic gene expression profiles.
Luanne Lukes, Nigel P S Crawford, Renard Walker, Kent W Hunter.
Cancer Res, 2009 Jan 02; 69(1). PMID: 19118016    Free PMC article.
A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer.
Pierre Farmer, Hervé Bonnefoi, +18 authors, Mauro Delorenzi.
Nat Med, 2009 Jan 06; 15(1). PMID: 19122658
Highly Cited.
Recommendations from the EGAPP Working Group: can tumor gene expression profiling improve outcomes in patients with breast cancer?
Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group.
Genet Med, 2009 Jan 07; 11(1). PMID: 19125125    Free PMC article.
The utility of conventional and molecular pathology in managing breast cancer.
D Craig Allred.
Breast Cancer Res, 2009 Jan 16; 10 Suppl 4. PMID: 19128442    Free PMC article.
Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers.
Jérôme Eeckhoute, Mathieu Lupien, +4 authors, Myles Brown.
Genome Res, 2009 Jan 09; 19(3). PMID: 19129543    Free PMC article.
Validation study of the prognostic value of cyclin-dependent kinase (CDK)-based risk in Caucasian breast cancer patients.
J G H van Nes, V T H B M Smit, +11 authors, C J H van de Velde.
Br J Cancer, 2009 Jan 22; 100(3). PMID: 19156146    Free PMC article.
Dynamic modularity in protein interaction networks predicts breast cancer outcome.
Ian W Taylor, Rune Linding, +7 authors, Jeffrey L Wrana.
Nat Biotechnol, 2009 Feb 03; 27(2). PMID: 19182785
Highly Cited.
Selecting control genes for RT-QPCR using public microarray data.
Vlad Popovici, Darlene R Goldstein, +3 authors, Pratyaksha Wirapati.
BMC Bioinformatics, 2009 Feb 04; 10. PMID: 19187545    Free PMC article.
The macrophage colony-stimulating factor 1 response signature in breast carcinoma.
Andrew H Beck, Inigo Espinosa, +7 authors, Robert B West.
Clin Cancer Res, 2009 Feb 04; 15(3). PMID: 19188147    Free PMC article.
Ovarian cancer: a clinical challenge that needs some basic answers.
Kate Lawrenson, Simon A Gayther.
PLoS Med, 2009 Feb 06; 6(2). PMID: 19192945    Free PMC article.
Prognostic gene signatures for non-small-cell lung cancer.
Paul C Boutros, Suzanne K Lau, +6 authors, Igor Jurisica.
Proc Natl Acad Sci U S A, 2009 Feb 07; 106(8). PMID: 19196983    Free PMC article.
Highly Cited.
Supervised risk predictor of breast cancer based on intrinsic subtypes.
Joel S Parker, Michael Mullins, +17 authors, Philip S Bernard.
J Clin Oncol, 2009 Feb 11; 27(8). PMID: 19204204    Free PMC article.
Highly Cited.
Regulation of alphaB-crystallin gene expression by the transcription factor Ets1 in breast cancer.
Joshua D Bosman, Fruma Yehiely, Joseph R Evans, Vincent L Cryns.
Breast Cancer Res Treat, 2009 Feb 12; 119(1). PMID: 19205872    Free PMC article.
A voting approach to identify a small number of highly predictive genes using multiple classifiers.
Md Rafiul Hassan, M Maruf Hossain, +3 authors, Kotagiri Ramamohanarao.
BMC Bioinformatics, 2009 Feb 28; 10 Suppl 1. PMID: 19208118    Free PMC article.
Master regulators used as breast cancer metastasis classifier.
Wei Keat Lim, Eugenia Lyashenko, Andrea Califano.
Pac Symp Biocomput, 2009 Feb 13;. PMID: 19209726    Free PMC article.
High-density gene expression analysis of tumor-associated macrophages from mouse mammary tumors.
Laureen S Ojalvo, William King, Dianne Cox, Jeffrey W Pollard.
Am J Pathol, 2009 Feb 17; 174(3). PMID: 19218341    Free PMC article.
[Genome-wide expression profiling as a clinical tool: are we there yet?].
F C Geyer, T Decker, J S Reis-Filho.
Pathologe, 2009 Feb 17; 30(2). PMID: 19219435
Review.
Novel tumor sampling strategies to enable microarray gene expression signatures in breast cancer: a study to determine feasibility and reproducibility in the context of clinical care.
Christopher L Tebbit, Jun Zhai, +8 authors, John A Olson.
Breast Cancer Res Treat, 2009 Feb 19; 118(3). PMID: 19224362    Free PMC article.
Genomancy: predicting tumour response to cancer therapy based on the oracle of genetics.
P D Williams, J K Lee, D Theodorescu.
Curr Oncol, 2009 Feb 21; 16(1). PMID: 19229372    Free PMC article.
Transcription profiling of rheumatic diseases.
Lisa G M van Baarsen, Carina L Bos, Tineke C T M van der Pouw Kraan, Cornelis L Verweij.
Arthritis Res Ther, 2009 Feb 24; 11(1). PMID: 19232067    Free PMC article.
Review.
Reduced expression of a gene proliferation signature is associated with enhanced malignancy in colon cancer.
A Anjomshoaa, Y-H Lin, +10 authors, A E Reeve.
Br J Cancer, 2009 Feb 25; 99(6). PMID: 19238634    Free PMC article.
Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion.
Tim Eiseler, Heike Döppler, +2 authors, Peter Storz.
Breast Cancer Res, 2009 Feb 27; 11(1). PMID: 19243594    Free PMC article.
Iterative Bayesian Model Averaging: a method for the application of survival analysis to high-dimensional microarray data.
Amalia Annest, Roger E Bumgarner, Adrian E Raftery, Ka Yee Yeung.
BMC Bioinformatics, 2009 Feb 28; 10. PMID: 19245714    Free PMC article.
MIST: Maximum Information Spanning Trees for dimension reduction of biological data sets.
Bracken M King, Bruce Tidor.
Bioinformatics, 2009 Mar 06; 25(9). PMID: 19261718    Free PMC article.
Stromal signature identifies basal breast cancers.
Kristian Wennmalm, Arne Ostman, Jonas Bergh.
Nat Med, 2009 Mar 07; 15(3). PMID: 19265816
Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue.
Dung-Tsa Chen, Aejaz Nasir, +12 authors, Timothy Yeatman.
Breast Cancer Res Treat, 2009 Mar 07; 119(2). PMID: 19266279    Free PMC article.
A radiation-derived gene expression signature predicts clinical outcome for breast cancer patients.
Brian D Piening, Pei Wang, Aravind Subramanian, Amanda G Paulovich.
Radiat Res, 2009 Mar 10; 171(2). PMID: 19267539    Free PMC article.
Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer.
David S Hsu, Chaitanya R Acharya, +11 authors, Anil Potti.
Proc Natl Acad Sci U S A, 2009 Mar 13; 106(13). PMID: 19279207    Free PMC article.
Regulation of p53 by TopBP1: a potential mechanism for p53 inactivation in cancer.
Kang Liu, Naresh Bellam, +4 authors, Weei-Chin Lin.
Mol Cell Biol, 2009 Mar 18; 29(10). PMID: 19289498    Free PMC article.
A compact VEGF signature associated with distant metastases and poor outcomes.
Zhiyuan Hu, Cheng Fan, +10 authors, Charles M Perou.
BMC Med, 2009 Mar 18; 7. PMID: 19291283    Free PMC article.
High cyclin B1 expression is associated with poor survival in breast cancer.
K Aaltonen, R-M Amini, +4 authors, C Blomqvist.
Br J Cancer, 2009 Mar 19; 100(7). PMID: 19293801    Free PMC article.
Evaluation of malignancy-risk gene signature in breast cancer patients.
Dung-Tsa Chen, Aejaz Nasir, +3 authors, Timothy Yeatman.
Breast Cancer Res Treat, 2009 Mar 24; 120(1). PMID: 19306088    Free PMC article.
Prediction of breast cancer metastasis by genomic profiling: where do we stand?
Ulrich Pfeffer, Francesco Romeo, Douglas M Noonan, Adriana Albini.
Clin Exp Metastasis, 2009 Mar 25; 26(6). PMID: 19308665    Free PMC article.
Review.
Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum.
Hector R Wong, Natalie Cvijanovich, +9 authors, Genomics of Pediatric SIRS/Septic Shock Investigators.
Crit Care Med, 2009 Mar 28; 37(5). PMID: 19325468    Free PMC article.
A multi-marker assay to distinguish malignant melanomas from benign nevi.
Mohammed Kashani-Sabet, Javier Rangel, +7 authors, Richard W Sagebiel.
Proc Natl Acad Sci U S A, 2009 Apr 01; 106(15). PMID: 19332774    Free PMC article.
A network view of disease and compound screening.
Eric E Schadt, Stephen H Friend, David A Shaywitz.
Nat Rev Drug Discov, 2009 Apr 02; 8(4). PMID: 19337271
Highly Cited. Review.
Distant metastasis: not out of reach any more.
François Bertucci, Daniel Birnbaum.
J Biol, 2009 Apr 07; 8(3). PMID: 19344492    Free PMC article.
Review.
Gene expression profiles and breast cancer metastasis: a genetic perspective.
Kent W Hunter, Jude Alsarraj.
Clin Exp Metastasis, 2009 Apr 07; 26(6). PMID: 19347591    Free PMC article.
Review.
[Individualizing treatment for locally advanced rectal cancer].
T Liersch, H Rothe, B M Ghadimi, H Becker.
Chirurg, 2009 Apr 08; 80(4). PMID: 19350305
Review.
CCAAT/enhancer-binding protein beta: its role in breast cancer and associations with receptor tyrosine kinases.
Cynthia A Zahnow.
Expert Rev Mol Med, 2009 Apr 09; 11. PMID: 19351437    Free PMC article.
Review.
Overexpression and mislocalization of the chromosomal segregation protein separase in multiple human cancers.
Rene Meyer, Viacheslav Fofanov, +3 authors, Debananda Pati.
Clin Cancer Res, 2009 Apr 09; 15(8). PMID: 19351757    Free PMC article.
Translating the metastasis paradigm from scientific theory to clinical oncology.
Fei Dong, Anuradha S Budhu, Xin Wei Wang.
Clin Cancer Res, 2009 Apr 09; 15(8). PMID: 19351761    Free PMC article.
Coactivator function defines the active estrogen receptor alpha cistrome.
Mathieu Lupien, Jérôme Eeckhoute, +4 authors, Myles Brown.
Mol Cell Biol, 2009 Apr 15; 29(12). PMID: 19364822    Free PMC article.
Identifying set-wise differential co-expression in gene expression microarray data.
Sung Bum Cho, Jihun Kim, Ju Han Kim.
BMC Bioinformatics, 2009 Apr 18; 10. PMID: 19371436    Free PMC article.
Metastatic gene signatures and emerging novel prognostic tests in the management of early stage breast cancer.
Attila Tordai, Cornelia Liedtke, Lajos Pusztai.
Clin Exp Metastasis, 2009 Apr 22; 26(7). PMID: 19381845
Review.
Gene expression profiling of human lymph node metastases and matched primary breast carcinomas: clinical implications.
Mika Suzuki, David Tarin.
Mol Oncol, 2007 Sep 01; 1(2). PMID: 19383293    Free PMC article.
The MINDACT trial: the first prospective clinical validation of a genomic tool.
Fatima Cardoso, Martine Piccart-Gebhart, +2 authors, TRANSBIG Consortium.
Mol Oncol, 2007 Dec 01; 1(3). PMID: 19383299    Free PMC article.
Identification of a subset of breast carcinomas characterized by expression of cytokeratin 15: relationship between CK15+ progenitor/amplified cells and pre-malignant lesions and invasive disease.
Julio E Celis, Irina Gromova, +5 authors, José M A Moreira.
Mol Oncol, 2007 Dec 01; 1(3). PMID: 19383306    Free PMC article.
Targeted proteomic strategy for clinical biomarker discovery.
Ralph Schiess, Bernd Wollscheid, Ruedi Aebersold.
Mol Oncol, 2009 Apr 23; 3(1). PMID: 19383365    Free PMC article.
Highly Cited. Review.
Is bagging effective in the classification of small-sample genomic and proteomic data?
T T Vu, U M Braga-Neto.
EURASIP J Bioinform Syst Biol, 2009 Apr 25;. PMID: 19390645    Free PMC article.
Molecular characterization of apocrine carcinoma of the breast: validation of an apocrine protein signature in a well-defined cohort.
Julio E Celis, Teresa Cabezón, +7 authors, Fritz Rank.
Mol Oncol, 2009 Apr 28; 3(3). PMID: 19393583    Free PMC article.
Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma.
Gavin J Gordon, Lingsheng Dong, +9 authors, Raphael Bueno.
J Natl Cancer Inst, 2009 Apr 30; 101(9). PMID: 19401544    Free PMC article.
Analysis of differential gene expression in colorectal cancer and stroma using fluorescence-activated cell sorting purification.
M J Smith, A C Culhane, +8 authors, H P Redmond.
Br J Cancer, 2009 Apr 30; 100(9). PMID: 19401702    Free PMC article.
Genomic and proteomic biomarkers for cancer: a multitude of opportunities.
Michael A Tainsky.
Biochim Biophys Acta, 2009 May 02; 1796(2). PMID: 19406210    Free PMC article.
Review.
A mouse mammary gland involution mRNA signature identifies biological pathways potentially associated with breast cancer metastasis.
Torsten Stein, Nathan Salomonis, +2 authors, Barry A Gusterson.
J Mammary Gland Biol Neoplasia, 2009 May 02; 14(2). PMID: 19408105
Review.
CDK inhibitor p18(INK4c) is a downstream target of GATA3 and restrains mammary luminal progenitor cell proliferation and tumorigenesis.
Xin-Hai Pei, Feng Bai, +6 authors, Yue Xiong.
Cancer Cell, 2009 May 05; 15(5). PMID: 19411068    Free PMC article.
Molecular signatures of obstructive sleep apnea in adults: a review and perspective.
Erna S Arnardottir, Miroslaw Mackiewicz, +2 authors, Allan I Pack.
Sleep, 2009 May 06; 32(4). PMID: 19413140    Free PMC article.
Highly Cited. Review.
The role and regulation of the nuclear receptor co-activator AIB1 in breast cancer.
Tyler Lahusen, Ralf T Henke, +2 authors, Anna T Riegel.
Breast Cancer Res Treat, 2009 May 07; 116(2). PMID: 19418218    Free PMC article.
Review.
RelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1.
Xiaobo Wang, Karine Belguise, +9 authors, Gail E Sonenshein.
Mol Cell Biol, 2009 May 13; 29(14). PMID: 19433448    Free PMC article.
Recent advances in systemic therapy: new diagnostics and biological predictors of outcome in early breast cancer.
Catherine Oakman, Silvia Bessi, +3 authors, Angelo Di Leo.
Breast Cancer Res, 2009 May 14; 11(2). PMID: 19435470    Free PMC article.
Review.
The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer.
R Shah, P Smith, +5 authors, T Crook.
Br J Cancer, 2009 May 14; 100(10). PMID: 19436308    Free PMC article.
Systematic identification of transcription factors associated with patient survival in cancers.
Chao Cheng, Lei M Li, Pedro Alves, Mark Gerstein.
BMC Genomics, 2009 May 16; 10. PMID: 19442316    Free PMC article.
Mechanisms of bone metastases of breast cancer.
Larry J Suva, Robert J Griffin, Issam Makhoul.
Endocr Relat Cancer, 2009 May 16; 16(3). PMID: 19443538    Free PMC article.
Review.
Effects of sample size on robustness and prediction accuracy of a prognostic gene signature.
Seon-Young Kim.
BMC Bioinformatics, 2009 May 19; 10. PMID: 19445687    Free PMC article.
Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer.
Brian Bierie, Christine H Chung, +6 authors, Harold L Moses.
J Clin Invest, 2009 May 20; 119(6). PMID: 19451693    Free PMC article.
A novel information retrieval model for high-throughput molecular medicine modalities.
Firas H Wehbe, Steven H Brown, +3 authors, Constantin F Aliferis.
Cancer Inform, 2009 May 22; 8. PMID: 19458790    Free PMC article.
Statistical aspects of gene signatures and molecular targets.
Mithat Gönen.
Gastrointest Cancer Res, 2009 May 23; 3(2 Suppl). PMID: 19461917    Free PMC article.
Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer.
Roshan Agarwal, Ana-Maria Gonzalez-Angulo, +16 authors, Bryan T Hennessy.
Clin Cancer Res, 2009 May 28; 15(11). PMID: 19470724    Free PMC article.
Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression.
Jason A Reuter, Susana Ortiz-Urda, +6 authors, Paul A Khavari.
Cancer Cell, 2009 May 30; 15(6). PMID: 19477427    Free PMC article.
Fewer permutations, more accurate P-values.
Theo A Knijnenburg, Lodewyk F A Wessels, Marcel J T Reinders, Ilya Shmulevich.
Bioinformatics, 2009 May 30; 25(12). PMID: 19477983    Free PMC article.
Profile of estrogen-responsive genes in an estrogen-specific mammary gland outgrowth model.
Bonnie J Deroo, Sylvia C Hewitt, +3 authors, Kenneth S Korach.
Mol Reprod Dev, 2009 Jun 02; 76(8). PMID: 19484750    Free PMC article.
AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist.
Daniel R Rhodes, Bushra Ateeq, +13 authors, Arul M Chinnaiyan.
Proc Natl Acad Sci U S A, 2009 Jun 03; 106(25). PMID: 19487683    Free PMC article.
Prostate cancer regulatory networks.
Dario C Altieri, Lucia R Languino, +5 authors, Gary S Stein.
J Cell Biochem, 2009 Jun 06; 107(5). PMID: 19492418    Free PMC article.
Review.
Gene expression-based prognostic and predictive markers for breast cancer: a primer for practicing pathologists.
Chungyeul Kim, Yusuke Taniyama, Soonmyung Paik.
Arch Pathol Lab Med, 2009 Jun 06; 133(6). PMID: 19492877    Free PMC article.
Review.
A systems biology view of cancer.
Reinhard Laubenbacher, Valerie Hower, +5 authors, Steven Akman.
Biochim Biophys Acta, 2009 Jun 10; 1796(2). PMID: 19505535    Free PMC article.
Review.
Neoadjuvant chemotherapy for "triple negative" breast cancer: a review of current practice and future outlook.
Zeina Nahleh.
Med Oncol, 2009 Jun 11; 27(2). PMID: 19513864
Review.
HtrA serine proteases as potential therapeutic targets in cancer.
Jeremy Chien, Mara Campioni, Viji Shridhar, Alfonso Baldi.
Curr Cancer Drug Targets, 2009 Jun 13; 9(4). PMID: 19519315    Free PMC article.
Review.
A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis.
Scott Valastyan, Ferenc Reinhardt, +6 authors, Robert A Weinberg.
Cell, 2009 Jun 16; 137(6). PMID: 19524507    Free PMC article.
Highly Cited.
Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009.
A Goldhirsch, J N Ingle, +4 authors, Panel members.
Ann Oncol, 2009 Jun 19; 20(8). PMID: 19535820    Free PMC article.
Highly Cited.
Genomic predictors of outcome and treatment response in breast cancer.
Lara Dunn, Angela Demichele.
Mol Diagn Ther, 2009 Jun 23; 13(2). PMID: 19537843
Review.
The development of a comparison approach for Illumina bead chips unravels unexpected challenges applying newest generation microarrays.
Daniela Eggle, Svenja Debey-Pascher, Marc Beyer, Joachim L Schultze.
BMC Bioinformatics, 2009 Jun 23; 10. PMID: 19538710    Free PMC article.
Comparison of prognostic gene profiles using qRT-PCR in paraffin samples: a retrospective study in patients with early breast cancer.
Enrique Espinosa, Iker Sánchez-Navarro, +9 authors, Juan Angel Fresno Vara.
PLoS One, 2009 Jun 24; 4(6). PMID: 19547727    Free PMC article.
Expression of FOXA1 and GATA-3 in breast cancer: the prognostic significance in hormone receptor-negative tumours.
André Albergaria, Joana Paredes, +9 authors, Fernando Schmitt.
Breast Cancer Res, 2009 Jun 25; 11(3). PMID: 19549328    Free PMC article.
A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer.
Theresa A DiMeo, Kristen Anderson, +5 authors, Charlotte Kuperwasser.
Cancer Res, 2009 Jun 25; 69(13). PMID: 19549913    Free PMC article.
Highly Cited.
Role of human papillomavirus and its detection in potentially malignant and malignant head and neck lesions: updated review.
Ajay Kumar Chaudhary, Mamta Singh, Shanthy Sundaram, Ravi Mehrotra.
Head Neck Oncol, 2009 Jun 27; 1. PMID: 19555477    Free PMC article.
Review.
Intrinsic bias in breast cancer gene expression data sets.
Jonathan D Mosley, Ruth A Keri.
BMC Cancer, 2009 Jul 01; 9. PMID: 19563679    Free PMC article.
Genomic antagonism between retinoic acid and estrogen signaling in breast cancer.
Sujun Hua, Ralf Kittler, Kevin P White.
Cell, 2009 Jul 01; 137(7). PMID: 19563758    Free PMC article.
Highly Cited.
Breast cancer subtypes based on ER/PR and Her2 expression: comparison of clinicopathologic features and survival.
Adedayo A Onitilo, Jessica M Engel, Robert T Greenlee, Bickol N Mukesh.
Clin Med Res, 2009 Jul 04; 7(1-2). PMID: 19574486    Free PMC article.
Highly Cited.
Computational identification of a p38SAPK-regulated transcription factor network required for tumor cell quiescence.
Alejandro P Adam, Ajish George, +6 authors, Julio A Aguirre-Ghiso.
Cancer Res, 2009 Jul 09; 69(14). PMID: 19584293    Free PMC article.
DNA copy number aberrations in breast cancer by array comparative genomic hybridization.
Jian Li, Kai Wang, +6 authors, Lars Bolund.
Genomics Proteomics Bioinformatics, 2009 Jul 14; 7(1-2). PMID: 19591788    Free PMC article.
Clinical trial designs for predictive biomarker validation: theoretical considerations and practical challenges.
Sumithra J Mandrekar, Daniel J Sargent.
J Clin Oncol, 2009 Jul 15; 27(24). PMID: 19597023    Free PMC article.
Highly Cited.
cDNA microarray analysis of esophageal cancer: discoveries and prospects.
Yutaka Shimada, Fumiaki Sato, +2 authors, Kazuhiro Tsukada.
Gen Thorac Cardiovasc Surg, 2009 Jul 15; 57(7). PMID: 19597924
Review.
Rhomboid domain containing 2 (RHBDD2): a novel cancer-related gene over-expressed in breast cancer.
M C Abba, E Lacunza, +5 authors, C M Aldaz.
Biochim Biophys Acta, 2009 Jul 21; 1792(10). PMID: 19616622    Free PMC article.
Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer.
Marisa G Ponzo, Robert Lesurf, +12 authors, Morag Park.
Proc Natl Acad Sci U S A, 2009 Jul 21; 106(31). PMID: 19617568    Free PMC article.
Highly Cited.
A comparison of RNA amplification techniques at sub-nanogram input concentration.
Julie E Lang, Mark Jesus M Magbanua, +6 authors, Christopher M Haqq.
BMC Genomics, 2009 Jul 22; 10. PMID: 19619282    Free PMC article.
Low expression of a few genes indicates good prognosis in estrogen receptor positive breast cancer.
Steven Buechler.
BMC Cancer, 2009 Jul 22; 9. PMID: 19619298    Free PMC article.
RCP is a human breast cancer-promoting gene with Ras-activating function.
Jinqiu Zhang, Xuejing Liu, +14 authors, Lance David Miller.
J Clin Invest, 2009 Jul 22; 119(8). PMID: 19620787    Free PMC article.
Identification of pediatric septic shock subclasses based on genome-wide expression profiling.
Hector R Wong, Natalie Cvijanovich, +10 authors, Thomas P Shanley.
BMC Med, 2009 Jul 25; 7. PMID: 19624809    Free PMC article.
Development of a microarray platform for FFPET profiling: application to the classification of human tumors.
Sven Duenwald, Mingjie Zhou, +10 authors, Matthew Marton.
J Transl Med, 2009 Jul 30; 7. PMID: 19638234    Free PMC article.
The mRNA expression of SATB1 and SATB2 in human breast cancer.
Neill Patani, Wen Jiang, +2 authors, Kefah Mokbel.
Cancer Cell Int, 2009 Aug 01; 9. PMID: 19642980    Free PMC article.
CT-X antigen expression in human breast cancer.
Anita Grigoriadis, Otavia L Caballero, +11 authors, A Munro Neville.
Proc Natl Acad Sci U S A, 2009 Aug 05; 106(32). PMID: 19651608    Free PMC article.
A loss-of-function polymorphism in the propeptide domain of the LOX gene and breast cancer.
Chengyin Min, Ziyang Yu, +7 authors, Gail E Sonenshein.
Cancer Res, 2009 Aug 06; 69(16). PMID: 19654310    Free PMC article.
Multianalyte tests for the early detection of cancer: speedbumps and barriers.
Michael A Tainsky, Madhumita Chatterjee, +2 authors, Judith Abrams.
Biomark Insights, 2007 Jan 01; 2. PMID: 19662209    Free PMC article.
Inferring population histories using cultural data.
Deborah S Rogers, Marcus W Feldman, Paul R Ehrlich.
Proc Biol Sci, 2009 Aug 14; 276(1674). PMID: 19675007    Free PMC article.
State of the art of neoadjuvant chemotherapy in breast cancer: rationale, results and recent developments.
Arnd Honig, Lorenz Rieger, +3 authors, Erich-Franz Solomayer.
Ger Med Sci, 2005 Jan 01; 3. PMID: 19675725    Free PMC article.
Securin promotes the identification of favourable outcome in invasive breast cancer.
K Talvinen, H Karra, +5 authors, P Kronqvist.
Br J Cancer, 2009 Aug 20; 101(6). PMID: 19690544    Free PMC article.
A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response.
Sanjay Chandriani, Eirik Frengen, +4 authors, Michael D Cole.
PLoS One, 2009 Aug 20; 4(8). PMID: 19690609    Free PMC article.
Analysis of DNA microarray expression data.
Richard Simon.
Best Pract Res Clin Haematol, 2009 Aug 25; 22(2). PMID: 19698933    Free PMC article.
GEOGLE: context mining tool for the correlation between gene expression and the phenotypic distinction.
Yao Yu, Kang Tu, +5 authors, Yixue Li.
BMC Bioinformatics, 2009 Aug 26; 10. PMID: 19703314    Free PMC article.
Antiestrogen-resistant subclones of MCF-7 human breast cancer cells are derived from a common monoclonal drug-resistant progenitor.
Kathryn R Coser, Ben S Wittner, +8 authors, Toshi Shioda.
Proc Natl Acad Sci U S A, 2009 Aug 27; 106(34). PMID: 19706540    Free PMC article.
Trastuzumab in the management of early and advanced stage breast cancer.
Rupert Bartsch, Catharina Wenzel, Guenther G Steger.
Biologics, 2007 Mar 01; 1(1). PMID: 19707345    Free PMC article.
BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A.
Julian Puppe, Rinske Drost, +8 authors, Alexandra M Pietersen.
Breast Cancer Res, 2009 Aug 28; 11(4). PMID: 19709408    Free PMC article.
The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor.
Nigel P S Crawford, Hailiu Yang, Katherine R Mattaini, Kent W Hunter.
J Biol Chem, 2009 Aug 28; 284(42). PMID: 19710015    Free PMC article.
The Snf1-related kinase, Hunk, is essential for mammary tumor metastasis.
Gerald B W Wertheim, Thomas W Yang, +10 authors, Lewis A Chodosh.
Proc Natl Acad Sci U S A, 2009 Sep 01; 106(37). PMID: 19717424    Free PMC article.
Divide and conquer: progress in the molecular stratification of cancer.
Patrick Tan.
Yonsei Med J, 2009 Sep 01; 50(4). PMID: 19718393    Free PMC article.
Review.
Robust model selection for classification of microarrays.
Ikumi Suzuki, Takashi Takenouchi, +2 authors, Shin Ishii.
Cancer Inform, 2009 Sep 01; 7. PMID: 19718450    Free PMC article.
Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition.
Erica L McCoy, Ritsuko Iwanaga, +5 authors, Heide L Ford.
J Clin Invest, 2009 Sep 04; 119(9). PMID: 19726883    Free PMC article.
The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling.
Douglas S Micalizzi, Kimberly L Christensen, +9 authors, Heide L Ford.
J Clin Invest, 2009 Sep 04; 119(9). PMID: 19726885    Free PMC article.
Highly Cited.
Improvement of the clinical applicability of the Genomic Grade Index through a qRT-PCR test performed on frozen and formalin-fixed paraffin-embedded tissues.
Jérôme Toussaint, Anieta M Sieuwerts, +8 authors, Christos Sotiriou.
BMC Genomics, 2009 Sep 12; 10. PMID: 19744330    Free PMC article.
Genetic characterization of breast cancer and implications for clinical management.
Felipe C Geyer, Maria A Lopez-Garcia, Maryou B Lambros, Jorge S Reis-Filho.
J Cell Mol Med, 2009 Sep 17; 13(10). PMID: 19754664    Free PMC article.
Review.
The rapamycin-regulated gene expression signature determines prognosis for breast cancer.
Argun Akcakanat, Li Zhang, Spiridon Tsavachidis, Funda Meric-Bernstam.
Mol Cancer, 2009 Sep 26; 8. PMID: 19778445    Free PMC article.
Tumor-endothelial interaction links the CD44(+)/CD24(-) phenotype with poor prognosis in early-stage breast cancer.
Martin Buess, Michal Rajski, +2 authors, Christoph Rochlitz.
Neoplasia, 2009 Oct 02; 11(10). PMID: 19794958    Free PMC article.
Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model.
Anka Bric, Cornelius Miething, +12 authors, Scott W Lowe.
Cancer Cell, 2009 Oct 06; 16(4). PMID: 19800577    Free PMC article.
High resolution analysis of the human transcriptome: detection of extensive alternative splicing independent of transcriptional activity.
Weiyin Zhou, Margaret A Calciano, +11 authors, Richard Einstein.
BMC Genet, 2009 Oct 07; 10. PMID: 19804644    Free PMC article.
Identification of novel kinase targets for the treatment of estrogen receptor-negative breast cancer.
Corey Speers, Anna Tsimelzon, +7 authors, Powel Brown.
Clin Cancer Res, 2009 Oct 08; 15(20). PMID: 19808870    Free PMC article.
Association between a prognostic gene signature and functional gene sets.
Manuela Hummel, Klaus H Metzeler, +2 authors, Ulrich Mansmann.
Bioinform Biol Insights, 2008 Jan 01; 2. PMID: 19812786    Free PMC article.
Shining new light on 3D cell motility and the metastatic process.
Paolo P Provenzano, Kevin W Eliceiri, Patricia J Keely.
Trends Cell Biol, 2009 Oct 13; 19(11). PMID: 19819146    Free PMC article.
Review.
Making the case for molecular staging of malignant pleural mesothelioma.
Raphael Bueno.
Semin Thorac Cardiovasc Surg, 2009 Oct 14; 21(2). PMID: 19822292    Free PMC article.
Review.
Preinvasive breast cancer.
Dennis C Sgroi.
Annu Rev Pathol, 2009 Oct 15; 5. PMID: 19824828    Free PMC article.
Review.
Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage.
P P Provenzano, D R Inman, K W Eliceiri, P J Keely.
Oncogene, 2009 Oct 15; 28(49). PMID: 19826415    Free PMC article.
Highly Cited.
Prognostic and predictive factors and genetic analysis of early breast cancer.
Miguel Martín, Fernando González Palacios, +2 authors, José Schneider.
Clin Transl Oncol, 2009 Oct 16; 11(10). PMID: 19828405
Review.
Gene expression profile assays as predictors of distant recurrence-free survival in early-stage breast cancer.
Nicole M Kuderer, Gary H Lyman.
Cancer Invest, 2009 Oct 17; 27(9). PMID: 19832034    Free PMC article.
Review.
Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis.
Adrian M Jubb, Francesca M Buffa, Adrian L Harris.
J Cell Mol Med, 2009 Oct 21; 14(1-2). PMID: 19840191    Free PMC article.
Review.
Can survival prediction be improved by merging gene expression data sets?
Haleh Yasrebi, Peter Sperisen, Viviane Praz, Philipp Bucher.
PLoS One, 2009 Oct 24; 4(10). PMID: 19851466    Free PMC article.
Partial Correlation Estimation by Joint Sparse Regression Models.
Jie Peng, Pei Wang, Nengfeng Zhou, Ji Zhu.
J Am Stat Assoc, 2009 Nov 03; 104(486). PMID: 19881892    Free PMC article.
Highly Cited.
A multimarker prognostic assay for primary cutaneous melanoma.
Mohammed Kashani-Sabet, Suraj Venna, +11 authors, Richard W Sagebiel.
Clin Cancer Res, 2009 Nov 06; 15(22). PMID: 19887476    Free PMC article.
Activation of host wound responses in breast cancer microenvironment.
Melissa A Troester, Myung Hee Lee, +7 authors, Sallie Smith Schneider.
Clin Cancer Res, 2009 Nov 06; 15(22). PMID: 19887484    Free PMC article.
Circulating levels of matrix metalloproteinase-9 (MMP-9), neutrophil gelatinase-associated lipocalin (NGAL) and their complex MMP-9/NGAL in breast cancer disease.
Xeni Provatopoulou, Antonia Gounaris, +6 authors, George Zografos.
BMC Cancer, 2009 Nov 06; 9. PMID: 19889214    Free PMC article.
Altered serotonin physiology in human breast cancers favors paradoxical growth and cell survival.
Vaibhav P Pai, Aaron M Marshall, +2 authors, Nelson D Horseman.
Breast Cancer Res, 2009 Nov 12; 11(6). PMID: 19903352    Free PMC article.
Tight junctions: a barrier to the initiation and progression of breast cancer?
Kieran Brennan, Gozie Offiah, Elaine A McSherry, Ann M Hopkins.
J Biomed Biotechnol, 2009 Nov 19; 2010. PMID: 19920867    Free PMC article.
Review.
Gene expression profiling during early acute febrile stage of dengue infection can predict the disease outcome.
Eduardo J M Nascimento, Ulisses Braga-Neto, +9 authors, Ernesto T A Marques.
PLoS One, 2009 Nov 26; 4(11). PMID: 19936257    Free PMC article.
A comprehensive sensitivity analysis of microarray breast cancer classification under feature variability.
Herman M J Sontrop, Perry D Moerland, +2 authors, Wim F J Verhaegh.
BMC Bioinformatics, 2009 Nov 28; 10. PMID: 19941644    Free PMC article.
Histological and molecular types of breast cancer: is there a unifying taxonomy?
Britta Weigelt, Jorge S Reis-Filho.
Nat Rev Clin Oncol, 2009 Nov 28; 6(12). PMID: 19942925
Highly Cited. Review.
ZBRK1 acts as a metastatic suppressor by directly regulating MMP9 in cervical cancer.
Li-Fang Lin, Chih-Hung Chuang, +8 authors, Ju-Ming Wang.
Cancer Res, 2009 Dec 10; 70(1). PMID: 19996286    Free PMC article.
Refining gene signatures: a Bayesian approach.
Amira Djebbari, Aurélie Labbe.
BMC Bioinformatics, 2009 Dec 17; 10. PMID: 20003289    Free PMC article.
Survival prediction from clinico-genomic models--a comparative study.
Hege M Bøvelstad, Ståle Nygård, Ornulf Borgan.
BMC Bioinformatics, 2009 Dec 17; 10. PMID: 20003386    Free PMC article.
Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial.
Kathy S Albain, William E Barlow, +20 authors, Breast Cancer Intergroup of North America.
Lancet Oncol, 2009 Dec 17; 11(1). PMID: 20005174    Free PMC article.
Highly Cited.
Advances in translational bioinformatics: computational approaches for the hunting of disease genes.
Maricel G Kann.
Brief Bioinform, 2009 Dec 17; 11(1). PMID: 20007728    Free PMC article.
Expression signature developed from a complex series of mouse models accurately predicts human breast cancer survival.
Mei He, David P Mangiameli, +5 authors, Steven K Libutti.
Clin Cancer Res, 2009 Dec 24; 16(1). PMID: 20028755    Free PMC article.
Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy.
Guanglei Zhuang, Dana M Brantley-Sieders, +7 authors, Jin Chen.
Cancer Res, 2009 Dec 24; 70(1). PMID: 20028874    Free PMC article.
Application of RT-PCR in formalin-fixed and paraffin-embedded lung cancer tissues.
Fan Zhang, Zhuo-min Wang, +6 authors, Qing-hua Zhou.
Acta Pharmacol Sin, 2009 Dec 29; 31(1). PMID: 20037605    Free PMC article.
A gene expression signature of invasive potential in metastatic melanoma cells.
Aaron R Jeffs, Amy C Glover, +10 authors, Michael R Eccles.
PLoS One, 2009 Dec 31; 4(12). PMID: 20041153    Free PMC article.
Detection of gene pathways with predictive power for breast cancer prognosis.
Shuangge Ma, Michael R Kosorok.
BMC Bioinformatics, 2010 Jan 02; 11. PMID: 20043860    Free PMC article.
IGF-I induced genes in stromal fibroblasts predict the clinical outcome of breast and lung cancer patients.
Michal Rajski, Rosanna Zanetti-Dällenbach, +3 authors, Martin Buess.
BMC Med, 2010 Jan 07; 8. PMID: 20051100    Free PMC article.
Predictive value of progression-related gene classifier in primary non-muscle invasive bladder cancer.
Wun-Jae Kim, Eun-Jung Kim, +10 authors, Suk-Chul Bae.
Mol Cancer, 2010 Jan 12; 9. PMID: 20059769    Free PMC article.
Highly Cited.
Effect of training-sample size and classification difficulty on the accuracy of genomic predictors.
Vlad Popovici, Weijie Chen, +15 authors, Lajos Pusztai.
Breast Cancer Res, 2010 Jan 13; 12(1). PMID: 20064235    Free PMC article.
Association between the 21-gene recurrence score assay and risk of locoregional recurrence in node-negative, estrogen receptor-positive breast cancer: results from NSABP B-14 and NSABP B-20.
Eleftherios P Mamounas, Gong Tang, +7 authors, Norman Wolmark.
J Clin Oncol, 2010 Jan 13; 28(10). PMID: 20065188    Free PMC article.
Highly Cited.
Prognosis of hormone-dependent breast cancers: implications of the presence of dysfunctional transcriptional networks activated by insulin via the immune transcription factor T-bet.
Kasi McCune, Poornima Bhat-Nakshatri, +3 authors, Harikrishna Nakshatri.
Cancer Res, 2010 Jan 14; 70(2). PMID: 20068169    Free PMC article.
Genomic analyses as a guide to target identification and preclinical testing of mouse models of breast cancer.
Christina N Bennett, Jeffrey E Green.
Toxicol Pathol, 2010 Jan 19; 38(1). PMID: 20080934    Free PMC article.
Review.
Multi-platform whole-genome microarray analyses refine the epigenetic signature of breast cancer metastasis with gene expression and copy number.
Joseph Andrews, Wendy Kennette, +4 authors, David I Rodenhiser.
PLoS One, 2010 Jan 20; 5(1). PMID: 20084286    Free PMC article.
14-3-3Tau regulates ubiquitin-independent proteasomal degradation of p21, a novel mechanism of p21 downregulation in breast cancer.
Bing Wang, Kang Liu, +3 authors, Weei-Chin Lin.
Mol Cell Biol, 2010 Jan 21; 30(6). PMID: 20086099    Free PMC article.
The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells.
Eric A Ariazi, Eugen Brailoiu, +10 authors, V Craig Jordan.
Cancer Res, 2010 Jan 21; 70(3). PMID: 20086172    Free PMC article.
Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene.
F M Buffa, A L Harris, C M West, C J Miller.
Br J Cancer, 2010 Jan 21; 102(2). PMID: 20087356    Free PMC article.
Highly Cited.
Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer.
Yang Li, Lihua Zou, +9 authors, Zhigang Charles Wang.
Nat Med, 2010 Jan 26; 16(2). PMID: 20098429    Free PMC article.
Highly Cited.
3'-end sequencing for expression quantification (3SEQ) from archival tumor samples.
Andrew H Beck, Ziming Weng, +8 authors, Robert B West.
PLoS One, 2010 Jan 26; 5(1). PMID: 20098735    Free PMC article.
Simpler evaluation of predictions and signature stability for gene expression data.
Yvonne E Pittelkow, Susan R Wilson.
J Biomed Biotechnol, 2010 Jan 30; 2009. PMID: 20111740    Free PMC article.
A population-based gene signature is predictive of breast cancer survival and chemoresponse.
Shruti Rathnagiriswaran, Ying-Wooi Wan, +3 authors, Nancy L Guo.
Int J Oncol, 2010 Feb 04; 36(3). PMID: 20126981    Free PMC article.
Variability of gene expression profiles in human blood and lymphoblastoid cell lines.
Josine L Min, Amy Barrett, +7 authors, Mark I McCarthy.
BMC Genomics, 2010 Feb 10; 11. PMID: 20141636    Free PMC article.
Molecular risk assessment of BIG 1-98 participants by expression profiling using RNA from archival tissue.
Janine Antonov, Vlad Popovici, +9 authors, Rolf Jaggi.
BMC Cancer, 2010 Feb 11; 10. PMID: 20144231    Free PMC article.
An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis.
Tahera Zabuawala, David A Taffany, +8 authors, Michael C Ostrowski.
Cancer Res, 2010 Feb 11; 70(4). PMID: 20145133    Free PMC article.
A fuzzy gene expression-based computational approach improves breast cancer prognostication.
Benjamin Haibe-Kains, Christine Desmedt, +3 authors, Gianluca Bontempi.
Genome Biol, 2010 Feb 17; 11(2). PMID: 20156340    Free PMC article.
Search for the smallest random forest.
Heping Zhang, Minghui Wang.
Stat Interface, 2010 Feb 19; 2(3). PMID: 20165560    Free PMC article.
High-throughput assessment of CpG site methylation for distinguishing between HCV-cirrhosis and HCV-associated hepatocellular carcinoma.
Kellie J Archer, Valeria R Mas, Daniel G Maluf, Robert A Fisher.
Mol Genet Genomics, 2010 Feb 19; 283(4). PMID: 20165882    Free PMC article.
FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer.
Nicholas Turner, Alex Pearson, +12 authors, Alan Ashworth.
Cancer Res, 2010 Feb 25; 70(5). PMID: 20179196    Free PMC article.
Highly Cited.
Performance of feature selection methods.
Edward R Dougherty, Jianping Hua, Chao Sima.
Curr Genomics, 2010 Mar 02; 10(6). PMID: 20190952    Free PMC article.
Linking the septin expression with carcinogenesis.
Ming Liu, Suqin Shen, +2 authors, Long Yu.
Mol Biol Rep, 2010 Mar 03; 37(7). PMID: 20195767
Should adjuvant trastuzumab be offered in very early-stage (pT1a/bN0M0) HER2-neu-positive breast cancer? A current debate.
Fausto Petrelli, Sandro Barni.
Med Oncol, 2010 Mar 03; 28(2). PMID: 20195801
Review.
Gene expression in histologically normal epithelium from breast cancer patients and from cancer-free prophylactic mastectomy patients shares a similar profile.
K Graham, A de las Morenas, +10 authors, C L Rosenberg.
Br J Cancer, 2010 Mar 04; 102(8). PMID: 20197764    Free PMC article.
Pathway-BasedFeature Selection Algorithm for Cancer Microarray Data.
Nirmalya Bandyopadhyay, Tamer Kahveci, +2 authors, Sanjay Ranka.
Adv Bioinformatics, 2009 Jan 01;. PMID: 20204186    Free PMC article.
The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer.
Zhi Hu, Ge Huang, +7 authors, Jian-Hua Mao.
Breast Cancer Res, 2010 Mar 10; 12(2). PMID: 20211017    Free PMC article.
LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer.
Yoon-La Choi, Melanie Bocanegra, +6 authors, Jonathan R Pollack.
Cancer Res, 2010 Mar 11; 70(6). PMID: 20215510    Free PMC article.
Gene Expression Profiling in Hereditary, BRCA1-linked Breast Cancer: Preliminary Report.
Volha Dudaladava, Michał Jarzab, +8 authors, Katarzyna Lisowska.
Hered Cancer Clin Pract, 2006 Jan 01; 4(1). PMID: 20223001    Free PMC article.
Integrative mixture of experts to combine clinical factors and gene markers.
Kim-Anh Lê Cao, Emmanuelle Meugnier, Geoffrey J McLachlan.
Bioinformatics, 2010 Mar 13; 26(9). PMID: 20223834    Free PMC article.
Impact of missing value imputation on classification for DNA microarray gene expression data--a model-based study.
Youting Sun, Ulisses Braga-Neto, Edward R Dougherty.
EURASIP J Bioinform Syst Biol, 2009 Jan 01; 2009. PMID: 20224634    Free PMC article.
Subcellular localization of activated AKT in estrogen receptor- and progesterone receptor-expressing breast cancers: potential clinical implications.
Sunil Badve, Nikail R Collins, +10 authors, Harikrishna Nakshatri.
Am J Pathol, 2010 Mar 17; 176(5). PMID: 20228224    Free PMC article.
BRD7 is a candidate tumour suppressor gene required for p53 function.
Jarno Drost, Fiamma Mantovani, +8 authors, Giannino Del Sal.
Nat Cell Biol, 2010 Mar 17; 12(4). PMID: 20228809
Predictors of tumor progression during neoadjuvant chemotherapy in breast cancer.
Abigail S Caudle, Ana M Gonzalez-Angulo, +7 authors, Funda Meric-Bernstam.
J Clin Oncol, 2010 Mar 17; 28(11). PMID: 20231683    Free PMC article.
18F-FDG PET of locally invasive breast cancer and association of estrogen receptor status with standardized uptake value: microarray and immunohistochemical analysis.
Joseph R Osborne, Elisa Port, +5 authors, Steven Larson.
J Nucl Med, 2010 Mar 20; 51(4). PMID: 20237034    Free PMC article.
A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network.
Andrea Lunardi, Giulio Di Minin, +4 authors, Licio Collavin.
Proc Natl Acad Sci U S A, 2010 Mar 24; 107(14). PMID: 20308539    Free PMC article.
Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells.
Marjo de Graauw, Martine H van Miltenburg, +11 authors, Bob van de Water.
Proc Natl Acad Sci U S A, 2010 Mar 24; 107(14). PMID: 20308542    Free PMC article.
Optimized ranking and selection methods for feature selection with application in microarray experiments.
Xinping Cui, Haibing Zhao, Jason Wilson.
J Biopharm Stat, 2010 Mar 24; 20(2). PMID: 20309756    Free PMC article.
A genome-wide association study of prognosis in breast cancer.
Elizabeth M Azzato, Paul D P Pharoah, +8 authors, Peter Kraft.
Cancer Epidemiol Biomarkers Prev, 2010 Mar 25; 19(4). PMID: 20332263    Free PMC article.
A pathway-based classification of human breast cancer.
Michael L Gatza, Joseph E Lucas, +8 authors, Joseph R Nevins.
Proc Natl Acad Sci U S A, 2010 Mar 26; 107(15). PMID: 20335537    Free PMC article.
Highly Cited.
Clinical trials for predictive medicine: new challenges and paradigms.
Richard Simon.
Clin Trials, 2010 Mar 27; 7(5). PMID: 20338899    Free PMC article.
Protein interaction network underpins concordant prognosis among heterogeneous breast cancer signatures.
James Chen, Lee Sam, +5 authors, Yves A Lussier.
J Biomed Inform, 2010 Mar 31; 43(3). PMID: 20350617    Free PMC article.
Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery.
Sabine Tejpar, Monica Bertagnolli, +18 authors, Arnaud Roth.
Oncologist, 2010 Mar 31; 15(4). PMID: 20350999    Free PMC article.
Review.
Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer.
Chad J Creighton, Jenny C Chang, Jeffrey M Rosen.
J Mammary Gland Biol Neoplasia, 2010 Apr 01; 15(2). PMID: 20354771
Highly Cited. Review.
Expression of Long-chain Fatty Acyl-CoA Synthetase 4 in Breast and Prostate Cancers Is Associated with Sex Steroid Hormone Receptor Negativity.
Marie E Monaco, Chad J Creighton, +3 authors, Diana M Stafforini.
Transl Oncol, 2010 Apr 03; 3(2). PMID: 20360933    Free PMC article.
Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome.
William T Barry, Dawn N Kernagis, +9 authors, Michael B Datto.
J Clin Oncol, 2010 Apr 07; 28(13). PMID: 20368555    Free PMC article.
Biomarkers and surrogate end points--the challenge of statistical validation.
Marc Buyse, Daniel J Sargent, +2 authors, Aimery de Gramont.
Nat Rev Clin Oncol, 2010 Apr 07; 7(6). PMID: 20368727
Review.
Microarray applications in cancer research.
Il-Jin Kim, Hio Chung Kang, Jae-Gahb Park.
Cancer Res Treat, 2004 Aug 01; 36(4). PMID: 20368836    Free PMC article.
Functional genomics of endothelial cells treated with anti-angiogenic or angiopreventive drugs.
Adriana Albini, Stefano Indraccolo, Douglas M Noonan, Ulrich Pfeffer.
Clin Exp Metastasis, 2010 Apr 13; 27(6). PMID: 20383568
Review.
HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.
Penney M Gilbert, Janna K Mouw, +11 authors, Valerie M Weaver.
J Clin Invest, 2010 Apr 15; 120(5). PMID: 20389018    Free PMC article.
Clinical outcome of breast cancer patients with N3a (≥10 positive lymph nodes) disease: has it changed over years?
Gul Basaran, Cabuk Devrim, +9 authors, Serdar N Turhal.
Med Oncol, 2010 Apr 15; 28(3). PMID: 20390469
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.
Rajnish A Gupta, Nilay Shah, +15 authors, Howard Y Chang.
Nature, 2010 Apr 16; 464(7291). PMID: 20393566    Free PMC article.
Highly Cited.
A CD8+ T cell transcription signature predicts prognosis in autoimmune disease.
Eoin F McKinney, Paul A Lyons, +11 authors, Kenneth G C Smith.
Nat Med, 2010 Apr 20; 16(5). PMID: 20400961    Free PMC article.
Highly Cited.
Personalized medicine in oncology: the future is now.
Richard L Schilsky.
Nat Rev Drug Discov, 2010 May 01; 9(5). PMID: 20431568
Review.
Gene-expression-based prognostic assays for breast cancer.
Chungyeul Kim, Soonmyung Paik.
Nat Rev Clin Oncol, 2010 May 05; 7(6). PMID: 20440284
Review.
Histological types of breast cancer: how special are they?
Britta Weigelt, Felipe C Geyer, Jorge S Reis-Filho.
Mol Oncol, 2010 May 11; 4(3). PMID: 20452298    Free PMC article.
Highly Cited. Review.
Biomarker-led adaptive trial blazes a trail in breast cancer.
Malorye Allison.
Nat Biotechnol, 2010 May 12; 28(5). PMID: 20458285
Protein-protein interaction reveals synergistic discrimination of cancer phenotype.
Jianghui Xiong, Juan Liu, +2 authors, Shanguang Chen.
Cancer Inform, 2010 May 12; 9. PMID: 20458363    Free PMC article.
On the theory of tumor self-seeding: implications for metastasis progression in humans.
Julio A Aguirre-Ghiso.
Breast Cancer Res, 2010 May 13; 12(2). PMID: 20459594    Free PMC article.
Cell polarity in motion: redefining mammary tissue organization through EMT and cell polarity transitions.
Nathan J Godde, Ryan C Galea, Imogen A Elsum, Patrick O Humbert.
J Mammary Gland Biol Neoplasia, 2010 May 13; 15(2). PMID: 20461450
Review.
Molecular basis for therapy resistance.
Per E Lønning.
Mol Oncol, 2010 May 15; 4(3). PMID: 20466604    Free PMC article.
Review.
An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer.
Raj Chari, Bradley P Coe, +2 authors, Wan L Lam.
BMC Syst Biol, 2010 May 19; 4. PMID: 20478067    Free PMC article.
Use of ER/PR/HER2 subtypes in conjunction with the 2007 St Gallen Consensus Statement for early breast cancer.
Katrina Bauer, Carol Parise, Vincent Caggiano.
BMC Cancer, 2010 May 25; 10. PMID: 20492696    Free PMC article.
Prediction of breast cancer prognosis using gene set statistics provides signature stability and biological context.
Gad Abraham, Adam Kowalczyk, +2 authors, Justin Zobel.
BMC Bioinformatics, 2010 May 27; 11. PMID: 20500821    Free PMC article.
Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer.
Adam C Pond, Jason I Herschkowitz, +9 authors, Jeffrey M Rosen.
Cancer Res, 2010 May 27; 70(12). PMID: 20501844    Free PMC article.
Current gene expression studies in esophageal carcinoma.
Wei Guo, Yao-Guang Jiang.
Curr Genomics, 2010 Jun 02; 10(8). PMID: 20514215    Free PMC article.
Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin.
Jin-Min Nam, Yasuhito Onodera, Mina J Bissell, Catherine C Park.
Cancer Res, 2010 Jun 03; 70(13). PMID: 20516121    Free PMC article.
Prognostic significance of subtype classification for short- and long-term survival in breast cancer: survival time holds the key.
Stefan Ambs.
PLoS Med, 2010 Jun 04; 7(5). PMID: 20520798    Free PMC article.
Quantitative expression profiling in formalin-fixed paraffin-embedded samples by affymetrix microarrays.
Diana Abdueva, Michele Wing, +2 authors, Elai Davicioni.
J Mol Diagn, 2010 Jun 05; 12(4). PMID: 20522636    Free PMC article.
Assessing risk prediction models in case-control studies using semiparametric and nonparametric methods.
Ying Huang, Margaret Sullivan Pepe.
Stat Med, 2010 Jun 09; 29(13). PMID: 20527013    Free PMC article.
Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM.
Charles J Vaske, Stephen C Benz, +5 authors, Joshua M Stuart.
Bioinformatics, 2010 Jun 10; 26(12). PMID: 20529912    Free PMC article.
Highly Cited.
Triple-negative breast cancer: present challenges and new perspectives.
Franca Podo, Lutgarde M C Buydens, +16 authors, FEMME Consortium.
Mol Oncol, 2010 Jun 12; 4(3). PMID: 20537966    Free PMC article.
Highly Cited. Review.
miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers.
G Vetter, A Saumet, +8 authors, E Friederich.
Oncogene, 2010 Jun 15; 29(31). PMID: 20543867    Free PMC article.
Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53.
Chad Deisenroth, Aaron R Thorner, +2 authors, Yanping Zhang.
Mol Cell Biol, 2010 Jun 16; 30(16). PMID: 20547751    Free PMC article.
Does applicability domain exist in microarray-based genomic research?
Li Shao, Leihong Wu, +2 authors, Xiaohui Fan.
PLoS One, 2010 Jun 16; 5(6). PMID: 20548774    Free PMC article.
Molecular circuits of solid tumors: prognostic and predictive tools for bedside use.
Charles Ferté, Fabrice André, Jean-Charles Soria.
Nat Rev Clin Oncol, 2010 Jun 17; 7(7). PMID: 20551944
Review.
Cardiovascular genetic medicine: the genetics of coronary heart disease.
David Seo, Pascal J Goldschmidt-Clermont.
J Cardiovasc Transl Res, 2008 Jun 01; 1(2). PMID: 20559911
Review.
Cardiovascular genetic medicine: genomic assessment of prognosis and diagnosis in patients with cardiomyopathy and heart failure.
Bettina Heidecker, Joshua M Hare.
J Cardiovasc Transl Res, 2008 Sep 01; 1(3). PMID: 20559924    Free PMC article.
Review.
Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer.
Chad J Creighton, Xiaoyong Fu, +11 authors, Rachel Schiff.
Breast Cancer Res, 2010 Jun 24; 12(3). PMID: 20569503    Free PMC article.
Highly Cited.
Expectations, validity, and reality in gene expression profiling.
Kyoungmi Kim, Stanislav O Zakharkin, David B Allison.
J Clin Epidemiol, 2010 Jun 29; 63(9). PMID: 20579843    Free PMC article.
Review.
Integrative genomic profiling of human prostate cancer.
Barry S Taylor, Nikolaus Schultz, +23 authors, William L Gerald.
Cancer Cell, 2010 Jun 29; 18(1). PMID: 20579941    Free PMC article.
Highly Cited.
Protein kinase D as a potential new target for cancer therapy.
Courtney R LaValle, Kara M George, +3 authors, Q Jane Wang.
Biochim Biophys Acta, 2010 Jun 29; 1806(2). PMID: 20580776    Free PMC article.
Review.
Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity.
Frédéric Chibon, Pauline Lagarde, +17 authors, Alain Aurias.
Nat Med, 2010 Jun 29; 16(7). PMID: 20581836
Highly Cited.
An 8-gene qRT-PCR-based gene expression score that has prognostic value in early breast cancer.
Iker Sánchez-Navarro, Angelo Gámez-Pozo, +11 authors, Enrique Espinosa.
BMC Cancer, 2010 Jun 30; 10. PMID: 20584321    Free PMC article.
A breast cancer prognostic signature predicts clinical outcomes in multiple tumor types.
Ying-Wooi Wan, Yong Qian, +2 authors, Nancy Lan Guo.
Oncol Rep, 2010 Jul 03; 24(2). PMID: 20596637    Free PMC article.
AACR centennial series: the biology of cancer metastasis: historical perspective.
James E Talmadge, Isaiah J Fidler.
Cancer Res, 2010 Jul 09; 70(14). PMID: 20610625    Free PMC article.
Highly Cited. Review.
The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer.
J Yu, Q Cao, +13 authors, A M Chinnaiyan.
Oncogene, 2010 Jul 14; 29(39). PMID: 20622896    Free PMC article.
Deletion of the PER3 gene on chromosome 1p36 in recurrent ER-positive breast cancer.
Joan Climent, Jesus Perez-Losada, +7 authors, Allan Balmain.
J Clin Oncol, 2010 Jul 14; 28(23). PMID: 20625127    Free PMC article.
Gene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy.
Ramón García-Escudero, Ana B Martínez-Cruz, +8 authors, Jesús M Paramio.
Mol Cancer, 2010 Jul 16; 9. PMID: 20630075    Free PMC article.
Toward a clinically feasible gene expression-based subclassification strategy for septic shock: proof of concept.
Hector R Wong, Derek S Wheeler, +6 authors, Lesley A Doughty.
Crit Care Med, 2010 Jul 20; 38(10). PMID: 20639748    Free PMC article.
Technology as a force for improved diagnosis and treatment of breast disease.
Claire M B Holloway, Alexandra Easson, +5 authors, David R McCready.
Can J Surg, 2010 Jul 22; 53(4). PMID: 20646402    Free PMC article.
Review.
Ceramide galactosyltransferase (UGT8) is a molecular marker of breast cancer malignancy and lung metastases.
P Dzięgiel, T Owczarek, +6 authors, M Ugorski.
Br J Cancer, 2010 Jul 22; 103(4). PMID: 20648017    Free PMC article.
Troglitazone suppresses telomerase activity independently of PPARgamma in estrogen-receptor negative breast cancer cells.
Fariborz Rashid-Kolvear, Michael A S Taboski, +3 authors, Susan J Done.
BMC Cancer, 2010 Jul 24; 10. PMID: 20650001    Free PMC article.
Integrated miRNA and mRNA expression profiling of the inflammatory breast cancer subtype.
I Van der Auwera, R Limame, +3 authors, S J Van Laere.
Br J Cancer, 2010 Jul 29; 103(4). PMID: 20664596    Free PMC article.
Finding biomarker signatures in pooled sample designs: a simulation framework for methodological comparisons.
Anna Telaar, Gerd Nürnberg, Dirk Repsilber.
Adv Bioinformatics, 2010 Jul 31;. PMID: 20671968    Free PMC article.
Consistency of predictive signature genes and classifiers generated using different microarray platforms.
X Fan, E K Lobenhofer, +21 authors, W Tong.
Pharmacogenomics J, 2010 Aug 03; 10(4). PMID: 20676064    Free PMC article.
Homeobox transcription factor muscle segment homeobox 2 (Msx2) correlates with good prognosis in breast cancer patients and induces apoptosis in vitro.
Fiona Lanigan, Gabriela Gremel, +4 authors, William M Gallagher.
Breast Cancer Res, 2010 Aug 05; 12(4). PMID: 20682066    Free PMC article.
Ferroportin and iron regulation in breast cancer progression and prognosis.
Zandra K Pinnix, Lance D Miller, +9 authors, Frank M Torti.
Sci Transl Med, 2010 Aug 06; 2(43). PMID: 20686179    Free PMC article.
Highly Cited.
Identifying genes progressively silenced in preneoplastic and neoplastic liver tissues.
Kellie J Archer, Zhongming Zhao, +3 authors, Valeria R Mas.
Int J Comput Biol Drug Des, 2010 Aug 10; 3(1). PMID: 20693610    Free PMC article.
The Expression Patterns of ER, PR, HER2, CK5/6, EGFR, Ki-67 and AR by Immunohistochemical Analysis in Breast Cancer Cell Lines.
Kristina Subik, Jin-Feng Lee, +8 authors, Ping Tang.
Breast Cancer (Auckl), 2010 Aug 11; 4. PMID: 20697531    Free PMC article.
Highly Cited.
Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool.
Y H Chia, M J Ellis, C X Ma.
Br J Cancer, 2010 Aug 12; 103(6). PMID: 20700118    Free PMC article.
Review.
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
Geoff S Higgins, Adrian L Harris, +3 authors, Francesca M Buffa.
Oncotarget, 2010 Aug 12; 1(3). PMID: 20700469    Free PMC article.
Individualized medicine 2010.
Hubert E Blum.
J Cell Mol Med, 2010 Aug 25; 14(9). PMID: 20731747    Free PMC article.
Enumerating the gene sets in breast cancer, a "direct" alternative to hierarchical clustering.
Dwain Mefford, Joel A Mefford.
BMC Genomics, 2010 Aug 25; 11. PMID: 20731868    Free PMC article.
Breast cancer prognostic classification in the molecular era: the role of histological grade.
Emad A Rakha, Jorge S Reis-Filho, +15 authors, Ian O Ellis.
Breast Cancer Res, 2010 Sep 02; 12(4). PMID: 20804570    Free PMC article.
Highly Cited. Review.
Hybrid models identified a 12-gene signature for lung cancer prognosis and chemoresponse prediction.
Ying-Wooi Wan, Ebrahim Sabbagh, +6 authors, Nancy Lan Guo.
PLoS One, 2010 Sep 03; 5(8). PMID: 20808922    Free PMC article.
An algorithm to discover gene signatures with predictive potential.
Robin M Hallett, Anna Dvorkin, Christine M Gabardo, John A Hassell.
J Exp Clin Cancer Res, 2010 Sep 04; 29. PMID: 20813028    Free PMC article.
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer.
Aleix Prat, Joel S Parker, +5 authors, Charles M Perou.
Breast Cancer Res, 2010 Sep 04; 12(5). PMID: 20813035    Free PMC article.
Highly Cited.
EGFR signaling in breast cancer: bad to the bone.
John Foley, Nicole K Nickerson, +4 authors, David J Riese.
Semin Cell Dev Biol, 2010 Sep 04; 21(9). PMID: 20813200    Free PMC article.
Review.
Aberrant expression of LMO4 induces centrosome amplification and mitotic spindle abnormalities in breast cancer cells.
Marjorie E Montañez-Wiscovich, Melissa D Shelton, +6 authors, Ruth A Keri.
J Pathol, 2010 Sep 04; 222(3). PMID: 20814902    Free PMC article.
Inferring cancer subnetwork markers using density-constrained biclustering.
Phuong Dao, Recep Colak, +4 authors, Martin Ester.
Bioinformatics, 2010 Sep 09; 26(18). PMID: 20823331    Free PMC article.
Perspectives on Breast Cancer Management: Tailoring Treatment to the Individual Patient.
Christoph Thomssen.
Breast Care (Basel), 2008 Jan 01; 3(s1). PMID: 20824005    Free PMC article.
Analyzing the regulation of metabolic pathways in human breast cancer.
Gunnar Schramm, Eva-Maria Surmann, +4 authors, Rainer König.
BMC Med Genomics, 2010 Sep 14; 3. PMID: 20831783    Free PMC article.
Semi-supervised recursively partitioned mixture models for identifying cancer subtypes.
Devin C Koestler, Carmen J Marsit, +5 authors, E Andres Houseman.
Bioinformatics, 2010 Sep 14; 26(20). PMID: 20834038    Free PMC article.
A systems biology approach to defining metastatic biomarkers and signaling pathways.
Natalie E Goldberger, Kent W Hunter.
Wiley Interdiscip Rev Syst Biol Med, 2009 Jul 01; 1(1). PMID: 20835983    Free PMC article.
Review.
Golgi calcium pump secretory pathway calcium ATPase 1 (SPCA1) is a key regulator of insulin-like growth factor receptor (IGF1R) processing in the basal-like breast cancer cell line MDA-MB-231.
Desma M Grice, Irina Vetter, +3 authors, Gregory R Monteith.
J Biol Chem, 2010 Sep 15; 285(48). PMID: 20837466    Free PMC article.
Undetectable and Decreased Expression of KIAA1949 (Phostensin) Encoded on Chromosome 6p21.33 in Human Breast Cancers Revealed by Transcriptome Analysis.
Yan A Su, Jun Yang, +2 authors, Ping He.
J Cancer, 2010 Sep 16; 1. PMID: 20842223    Free PMC article.
Micrometastatic disease and isolated tumor cells as a predictor for additional breast cancer axillary metastatic burden.
Amy Cyr, William E Gillanders, +3 authors, Julie A Margenthaler.
Ann Surg Oncol, 2010 Oct 01; 17 Suppl 3. PMID: 20853051    Free PMC article.
Dysregulated miR-183 inhibits migration in breast cancer cells.
Aoife J Lowery, Nicola Miller, Roisin M Dwyer, Michael J Kerin.
BMC Cancer, 2010 Sep 23; 10. PMID: 20858276    Free PMC article.
Expression profiling in canine osteosarcoma: identification of biomarkers and pathways associated with outcome.
Liza E O'Donoghue, Andrey A Ptitsyn, +3 authors, Dawn L Duval.
BMC Cancer, 2010 Sep 24; 10. PMID: 20860831    Free PMC article.
Triple-negative, basal-like, and quintuple-negative breast cancers: better prediction model for survival.
Yoon-La Choi, Ensel Oh, +12 authors, Young Kee Shin.
BMC Cancer, 2010 Sep 24; 10. PMID: 20860845    Free PMC article.
ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2.
Ekaterina V Kalashnikova, Alexey S Revenko, +6 authors, Hong-Wu Chen.
Cancer Res, 2010 Sep 25; 70(22). PMID: 20864510    Free PMC article.
Molecular Stratification of Clear Cell Renal Cell Carcinoma by Consensus Clustering Reveals Distinct Subtypes and Survival Patterns.
A Rose Brannon, Anupama Reddy, +13 authors, W Kimryn Rathmell.
Genes Cancer, 2010 Sep 28; 1(2). PMID: 20871783    Free PMC article.
Highly Cited.
Modulation of plasma complement by the initial dose of epirubicin/docetaxel therapy in breast cancer and its predictive value.
A Michlmayr, T Bachleitner-Hofmann, +12 authors, R Oehler.
Br J Cancer, 2010 Sep 30; 103(8). PMID: 20877360    Free PMC article.
Mechanisms of endocrine resistance in breast cancer.
C Kent Osborne, Rachel Schiff.
Annu Rev Med, 2010 Oct 05; 62. PMID: 20887199    Free PMC article.
Highly Cited. Review.
Store-independent activation of Orai1 by SPCA2 in mammary tumors.
Mingye Feng, Desma M Grice, +9 authors, Rajini Rao.
Cell, 2010 Oct 05; 143(1). PMID: 20887894    Free PMC article.
Highly Cited.
Growth factor stimulation induces a distinct ER(alpha) cistrome underlying breast cancer endocrine resistance.
Mathieu Lupien, Clifford A Meyer, +8 authors, Myles Brown.
Genes Dev, 2010 Oct 05; 24(19). PMID: 20889718    Free PMC article.
Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer.
John J Tentler, Sujatha Nallapareddy, +11 authors, S Gail Eckhardt.
Mol Cancer Ther, 2010 Oct 07; 9(12). PMID: 20923857    Free PMC article.
Robust assignment of cancer subtypes from expression data using a uni-variate gene expression average as classifier.
Martin Lauss, Attila Frigyesi, Tobias Ryden, Mattias Höglund.
BMC Cancer, 2010 Oct 12; 10. PMID: 20925936    Free PMC article.
A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer.
Christina Yau, Laura Esserman, +3 authors, Christopher C Benz.
Breast Cancer Res, 2010 Oct 16; 12(5). PMID: 20946665    Free PMC article.
Potential tumor suppressor role for the c-Myb oncogene in luminal breast cancer.
Aaron R Thorner, Joel S Parker, Katherine A Hoadley, Charles M Perou.
PLoS One, 2010 Oct 16; 5(10). PMID: 20949095    Free PMC article.
Proteomic characterization of Her2/neu-overexpressing breast cancer cells.
Hexin Chen, Genaro Pimienta, +8 authors, Akhilesh Pandey.
Proteomics, 2010 Oct 21; 10(21). PMID: 20960451    Free PMC article.
Comparative survival analysis of breast cancer microarray studies identifies important prognostic genetic pathways.
Jeffrey C Miecznikowski, Dan Wang, +2 authors, David Gold.
BMC Cancer, 2010 Oct 23; 10. PMID: 20964848    Free PMC article.
Identification of high-quality cancer prognostic markers and metastasis network modules.
Jie Li, Anne E G Lenferink, +5 authors, Edwin Wang.
Nat Commun, 2010 Oct 27; 1. PMID: 20975711    Free PMC article.
Highly Cited.
Breast cancer assessment tools and optimizing adjuvant therapy.
Catherine Oakman, Libero Santarpia, Angelo Di Leo.
Nat Rev Clin Oncol, 2010 Oct 27; 7(12). PMID: 20975745
Review.
DEGAS: de novo discovery of dysregulated pathways in human diseases.
Igor Ulitsky, Akshay Krishnamurthy, Richard M Karp, Ron Shamir.
PLoS One, 2010 Oct 27; 5(10). PMID: 20976054    Free PMC article.
Breast cancer in the personal genomics era.
Rachel E Ellsworth, David J Decewicz, Craig D Shriver, Darrell L Ellsworth.
Curr Genomics, 2010 Nov 03; 11(3). PMID: 21037853    Free PMC article.
Context-dependent bidirectional regulation of the MutS homolog 2 by transforming growth factor β contributes to chemoresistance in breast cancer cells.
Yang Yu, Yujun Wang, +4 authors, Shizhen Emily Wang.
Mol Cancer Res, 2010 Nov 05; 8(12). PMID: 21047769    Free PMC article.
Systems biology and genomics of breast cancer.
Charles M Perou, Anne-Lise Børresen-Dale.
Cold Spring Harb Perspect Biol, 2010 Nov 05; 3(2). PMID: 21047916    Free PMC article.
Review.
Adjuvant Systemic Therapy, Quo Vadis? Patient Selection, Prognostic and Predictive Factors.
Fatima Cardoso.
Breast Care (Basel), 2008 Jan 01; 3(6). PMID: 21048908    Free PMC article.
Improved prognostic classification of breast cancer defined by antagonistic activation patterns of immune response pathway modules.
Andrew E Teschendorff, Sergio Gomez, +4 authors, Carlos Caldas.
BMC Cancer, 2010 Nov 06; 10. PMID: 21050467    Free PMC article.
Multi-level reproducibility of signature hubs in human interactome for breast cancer metastasis.
Chen Yao, Hongdong Li, +3 authors, Zheng Guo.
BMC Syst Biol, 2010 Nov 10; 4. PMID: 21059271    Free PMC article.
The UCSC Cancer Genomics Browser: update 2011.
J Zachary Sanborn, Stephen C Benz, +12 authors, Jingchun Zhu.
Nucleic Acids Res, 2010 Nov 10; 39(Database issue). PMID: 21059681    Free PMC article.
Gene expression profiles of estrogen receptor-positive and estrogen receptor-negative breast cancers are detectable in histologically normal breast epithelium.
Kelly Graham, Xijin Ge, +2 authors, Carol L Rosenberg.
Clin Cancer Res, 2010 Nov 10; 17(2). PMID: 21059815    Free PMC article.
Node-Negative Breast Cancer: Which Patients Should Be Treated?
Marcus Schmidt.
Breast Care (Basel), 2008 Jan 01; 3(4). PMID: 21076603    Free PMC article.
Identification of a low-risk subgroup of HER-2-positive breast cancer by the 70-gene prognosis signature.
M Knauer, F Cardoso, +4 authors, L J van 't Veer.
Br J Cancer, 2010 Nov 18; 103(12). PMID: 21081926    Free PMC article.
Breast cancer biomarker discovery in the functional genomic age: a systematic review of 42 gene expression signatures.
M C Abba, E Lacunza, M Butti, C M Aldaz.
Biomark Insights, 2010 Nov 18; 5. PMID: 21082037    Free PMC article.
Tumor profiling: development of prognostic and predictive factors to guide brain tumor treatment.
Stephen H Settle, Erik P Sulman.
Curr Oncol Rep, 2010 Nov 18; 13(1). PMID: 21082294
Review.
Derivation of cancer diagnostic and prognostic signatures from gene expression data.
Steve Goodison, Yijun Sun, Virginia Urquidi.
Bioanalysis, 2010 Nov 19; 2(5). PMID: 21083217    Free PMC article.
Review.
Predicting prognosis of breast cancer with gene signatures: are we lost in a sea of data?
Takayuki Iwamoto, Lajos Pusztai.
Genome Med, 2010 Nov 26; 2(11). PMID: 21092148    Free PMC article.
Validation and characterization of DNA microarray gene expression data distribution and associated moments.
Reuben Thomas, Luis de la Torre, Xiaoqing Chang, Sanjay Mehrotra.
BMC Bioinformatics, 2010 Nov 26; 11. PMID: 21092329    Free PMC article.
BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations.
Henne Holstege, Hugo M Horlings, +5 authors, Jos Jonkers.
BMC Cancer, 2010 Dec 02; 10. PMID: 21118481    Free PMC article.
Cytosolic phospholipase A2-α expression in breast cancer is associated with EGFR expression and correlates with an adverse prognosis in luminal tumours.
F Caiazza, N S McCarthy, +3 authors, W Thomas.
Br J Cancer, 2010 Dec 02; 104(2). PMID: 21119660    Free PMC article.
Nearest template prediction: a single-sample-based flexible class prediction with confidence assessment.
Yujin Hoshida.
PLoS One, 2010 Dec 03; 5(11). PMID: 21124904    Free PMC article.
Exploring the link between germline and somatic genetic alterations in breast carcinogenesis.
Núria Bonifaci, Bohdan Górski, +12 authors, Miguel Angel Pujana.
PLoS One, 2010 Dec 03; 5(11). PMID: 21124932    Free PMC article.
In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome.
Simen Myhre, Hayat Mohammed, +7 authors, Therese Sørlie.
PLoS One, 2010 Dec 03; 5(11). PMID: 21124964    Free PMC article.
The α₂β₁ integrin is a metastasis suppressor in mouse models and human cancer.
Norma E Ramirez, Zhonghua Zhang, +7 authors, Mary M Zutter.
J Clin Invest, 2010 Dec 08; 121(1). PMID: 21135504    Free PMC article.
Prognostic gene network modules in breast cancer hold promise.
Andrew E Teschendorff, Yan Jiao, Carlos Caldas.
Breast Cancer Res, 2010 Dec 15; 12(6). PMID: 21143771    Free PMC article.
Deconstructing the molecular portraits of breast cancer.
Aleix Prat, Charles M Perou.
Mol Oncol, 2010 Dec 15; 5(1). PMID: 21147047    Free PMC article.
Highly Cited. Review.
Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium.
Dana M Brantley-Sieders, Charlene M Dunaway, +8 authors, Jin Chen.
Cancer Res, 2010 Dec 15; 71(3). PMID: 21148069    Free PMC article.
Biological functions of the genes in the mammaprint breast cancer profile reflect the hallmarks of cancer.
Sun Tian, Paul Roepman, +3 authors, Annuska M Glas.
Biomark Insights, 2010 Dec 15; 5. PMID: 21151591    Free PMC article.
Prognostic biomarkers for esophageal adenocarcinoma identified by analysis of tumor transcriptome.
Soo Mi Kim, Yun-Yong Park, +14 authors, Ju-Seog Lee.
PLoS One, 2010 Dec 15; 5(11). PMID: 21152079    Free PMC article.
Mesenchymal/stromal gene expression signature relates to basal-like breast cancers, identifies bone metastasis and predicts resistance to therapies.
Cristina Marchini, Maura Montani, +14 authors, Augusto Amici.
PLoS One, 2010 Dec 15; 5(11). PMID: 21152434    Free PMC article.
The role of S100 genes in breast cancer progression.
Eadaoin McKiernan, Enda W McDermott, +2 authors, Michael J Duffy.
Tumour Biol, 2010 Dec 15; 32(3). PMID: 21153724
A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients.
Stephanie Roessler, Hu-Liang Jia, +8 authors, Xin Wei Wang.
Cancer Res, 2010 Dec 17; 70(24). PMID: 21159642    Free PMC article.
Highly Cited.
A 12-gene genomic instability signature predicts clinical outcomes in multiple cancer types.
Rama K R Mettu, Ying-Wooi Wan, +2 authors, Nancy Lan Guo.
Int J Biol Markers, 2010 Dec 17; 25(4). PMID: 21161944    Free PMC article.
MDM2 regulates estrogen receptor α and estrogen responsiveness in breast cancer cells.
Kyounghyun Kim, Robert Burghardt, +3 authors, Stephen Safe.
J Mol Endocrinol, 2010 Dec 21; 46(2). PMID: 21169420    Free PMC article.
TSPYL5 suppresses p53 levels and function by physical interaction with USP7.
Mirjam T Epping, Lars A T Meijer, +3 authors, René Bernards.
Nat Cell Biol, 2010 Dec 21; 13(1). PMID: 21170034
Trefoil factor 3 is oncogenic and mediates anti-estrogen resistance in human mammary carcinoma.
Nagarajan Kannan, Jian Kang, +10 authors, Peter E Lobie.
Neoplasia, 2010 Dec 21; 12(12). PMID: 21170268    Free PMC article.
Expression profiling of formalin-fixed paraffin-embedded primary breast tumors using cancer-specific and whole genome gene panels on the DASL® platform.
Monica M Reinholz, Jeanette E Eckel-Passow, +14 authors, Wilma L Lingle.
BMC Med Genomics, 2010 Dec 22; 3. PMID: 21172013    Free PMC article.
Basal-like breast cancers: the phenotypic disparity between the cancer-initiating cells and tumor histology.
Afshin Raouf.
Breast Cancer Res, 2010 Dec 22; 12(6). PMID: 21172068    Free PMC article.
Molecular profiling currently offers no more than tumour morphology and basic immunohistochemistry.
Britta Weigelt, Jorge S Reis-Filho.
Breast Cancer Res, 2011 Jan 05; 12 Suppl 4. PMID: 21172089    Free PMC article.
Manipulating protein acetylation in breast cancer: a promising approach in combination with hormonal therapies?
Aurélien Linares, Florence Dalenc, +2 authors, Vincent Cavailles.
J Biomed Biotechnol, 2010 Dec 29; 2011. PMID: 21188173    Free PMC article.
Review.
Long-term cultures of stem/progenitor cells from lobular and ductal breast carcinomas under non-adherent conditions.
Agostina Nardone, Sara Corvigno, +3 authors, Bianca Maria Veneziani.
Cytotechnology, 2010 Dec 29; 63(1). PMID: 21188518    Free PMC article.
Systems approaches to molecular cancer diagnostics.
Shuyi Ma, Cory C Funk, Nathan D Price.
Discov Med, 2010 Dec 30; 10(55). PMID: 21189224    Free PMC article.
Review.
A systems biological approach to identify key transcription factors and their genomic neighborhoods in human sarcomas.
Antti Ylipää, Olli Yli-Harja, Wei Zhang, Matti Nykter.
Chin J Cancer, 2011 Jan 05; 30(1). PMID: 21192842    Free PMC article.
Postoperative fever: the potential relationship with prognosis in node negative breast cancer patients.
Tingting Yan, Wenjin Yin, +4 authors, Jinsong Lu.
PLoS One, 2011 Jan 07; 5(12). PMID: 21209958    Free PMC article.
Building prognostic models for breast cancer patients using clinical variables and hundreds of gene expression signatures.
Cheng Fan, Aleix Prat, +4 authors, Charles M Perou.
BMC Med Genomics, 2011 Jan 11; 4. PMID: 21214954    Free PMC article.
Discovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancer.
Lei Zhang, Hua Xiao, +8 authors, David T Wong.
PLoS One, 2011 Jan 11; 5(12). PMID: 21217834    Free PMC article.
Comparison of the prognostic and predictive utilities of the 21-gene Recurrence Score assay and Adjuvant! for women with node-negative, ER-positive breast cancer: results from NSABP B-14 and NSABP B-20.
Gong Tang, Steven Shak, +6 authors, Norman Wolmark.
Breast Cancer Res Treat, 2011 Jan 12; 127(1). PMID: 21221771    Free PMC article.
Young age, increased tumor proliferation and FOXM1 expression predict early metastatic relapse only for endocrine-dependent breast cancers.
Christina Yau, Yixin Wang, +2 authors, Christopher C Benz.
Breast Cancer Res Treat, 2011 Jan 13; 126(3). PMID: 21225456    Free PMC article.
LOXL2-mediated matrix remodeling in metastasis and mammary gland involution.
Holly E Barker, Joan Chang, +6 authors, Janine T Erler.
Cancer Res, 2011 Jan 15; 71(5). PMID: 21233336    Free PMC article.
Highly Cited.
A Normalized Tree Index for identification of correlated clinical parameters in microarray experiments.
Christian W Martin, Anika Tauchen, Anke Becker, Tim W Nattkemper.
BioData Min, 2011 Jan 21; 4(1). PMID: 21247420    Free PMC article.
Prolactin-induced mouse mammary carcinomas model estrogen resistant luminal breast cancer.
Lisa M Arendt, Debra E Rugowski, +3 authors, Linda A Schuler.
Breast Cancer Res, 2011 Feb 01; 13(1). PMID: 21276249    Free PMC article.
Kernel machine approach to testing the significance of multiple genetic markers for risk prediction.
Tianxi Cai, Giulia Tonini, Xihong Lin.
Biometrics, 2011 Feb 02; 67(3). PMID: 21281275    Free PMC article.
The effect of a DNA repair gene on cellular invasiveness: XRCC3 over-expression in breast cancer cells.
Veronica L Martinez-Marignac, Amélie Rodrigue, +6 authors, Raquel Aloyz.
PLoS One, 2011 Feb 02; 6(1). PMID: 21283680    Free PMC article.
Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis.
Haijun Zhang, Fanyan Meng, +6 authors, Guojun Wu.
Cancer Res, 2011 Feb 03; 71(4). PMID: 21285253    Free PMC article.
MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer.
Kim J Png, Mitsukuni Yoshida, +13 authors, Sohail F Tavazoie.
Genes Dev, 2011 Feb 04; 25(3). PMID: 21289068    Free PMC article.
Highly Cited.
Gene expression profiling predicts the development of oral cancer.
Pierre Saintigny, Li Zhang, +7 authors, Li Mao.
Cancer Prev Res (Phila), 2011 Feb 05; 4(2). PMID: 21292635    Free PMC article.
Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial.
Armando E Giuliano, Kelly K Hunt, +7 authors, Monica Morrow.
JAMA, 2011 Feb 10; 305(6). PMID: 21304082    Free PMC article.
Highly Cited.
Charting a course for genomic medicine from base pairs to bedside.
Eric D Green, Mark S Guyer, National Human Genome Research Institute.
Nature, 2011 Feb 11; 470(7333). PMID: 21307933
Highly Cited.
A four-gene signature predicts disease progression in muscle invasive bladder cancer.
Wun-Jae Kim, Seon-Kyu Kim, +6 authors, Yung Hyun Choi.
Mol Med, 2011 Feb 11; 17(5-6). PMID: 21308147    Free PMC article.
Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study.
Jack Cuzick, Gregory P Swanson, +18 authors, Transatlantic Prostate Group.
Lancet Oncol, 2011 Feb 12; 12(3). PMID: 21310658    Free PMC article.
Highly Cited.
The human DEK oncogene stimulates β-catenin signaling, invasion and mammosphere formation in breast cancer.
L M Privette Vinnedge, R McClaine, +3 authors, S I Wells.
Oncogene, 2011 Feb 15; 30(24). PMID: 21317931    Free PMC article.
Implementing prognostic and predictive biomarkers in CRC clinical trials.
Sandra Van Schaeybroeck, Wendy L Allen, Richard C Turkington, Patrick G Johnston.
Nat Rev Clin Oncol, 2011 Feb 16; 8(4). PMID: 21321566
Review.
Challenges to developing proteomic-based breast cancer diagnostics.
Richard R Drake, Lisa H Cazares, +3 authors, Christine Laronga.
OMICS, 2011 Feb 22; 15(5). PMID: 21332380    Free PMC article.
Review.
Stem cell marker prominin-1 regulates branching morphogenesis, but not regenerative capacity, in the mammary gland.
Lisa H Anderson, Corinne A Boulanger, +2 authors, Christine J Watson.
Dev Dyn, 2011 Feb 22; 240(3). PMID: 21337465    Free PMC article.
High-resolution comparative genomic hybridization of inflammatory breast cancer and identification of candidate genes.
Ismahane Bekhouche, Pascal Finetti, +11 authors, François Bertucci.
PLoS One, 2011 Feb 23; 6(2). PMID: 21339811    Free PMC article.
Metastasis: new perspectives on an old problem.
Sandra Kraljevic Pavelic, Mirela Sedic, +2 authors, Kresimir Pavelic.
Mol Cancer, 2011 Feb 24; 10. PMID: 21342498    Free PMC article.
Review.
Gene signatures of breast cancer progression and metastasis.
David I Rodenhiser, Joseph D Andrews, Theodore A Vandenberg, Ann F Chambers.
Breast Cancer Res, 2011 Feb 25; 13(1). PMID: 21345283    Free PMC article.
Review.
Gene expression profiles from formalin fixed paraffin embedded breast cancer tissue are largely comparable to fresh frozen matched tissue.
Lorenza Mittempergher, Jorma J de Ronde, +5 authors, Laura J Van't Veer.
PLoS One, 2011 Feb 25; 6(2). PMID: 21347257    Free PMC article.
ENCODE tiling array analysis identifies differentially expressed annotated and novel 5' capped RNAs in hepatitis C infected liver.
Milan E Folkers, Don A Delker, +4 authors, Curt H Hagedorn.
PLoS One, 2011 Mar 02; 6(2). PMID: 21359205    Free PMC article.
Factors influencing the outcome of breast cancer patients with 10 or more metastasized axillary lymph nodes.
Jun Sang Lee, Seung Il Kim, +6 authors, Kyong Sik Lee.
Int J Clin Oncol, 2011 Mar 02; 16(5). PMID: 21360123
Can some patients avoid adjuvant chemotherapy for early-stage breast cancer?
Philippe L Bedard, Fatima Cardoso.
Nat Rev Clin Oncol, 2011 Mar 03; 8(5). PMID: 21364525
Review.
RNA expression of the molecular signature genes for metastasis in colorectal cancer.
Luciano Carvalho, Jinsheng Yu, +2 authors, James W Fleshman.
Oncol Rep, 2011 Mar 08; 25(5). PMID: 21380492    Free PMC article.
Global gene expression profiling and validation in esophageal squamous cell carcinoma and its association with clinical phenotypes.
Hua Su, Nan Hu, +10 authors, Philip R Taylor.
Clin Cancer Res, 2011 Mar 10; 17(9). PMID: 21385931    Free PMC article.
Highly Cited.
Taming the dragon: genomic biomarkers to individualize the treatment of cancer.
Ian J Majewski, René Bernards.
Nat Med, 2011 Mar 10; 17(3). PMID: 21386834
A signature inferred from Drosophila mitotic genes predicts survival of breast cancer patients.
Christian Damasco, Antonio Lembo, +3 authors, Paolo Provero.
PLoS One, 2011 Mar 10; 6(2). PMID: 21386884    Free PMC article.
The dChip survival analysis module for microarray data.
Samir B Amin, Parantu K Shah, +5 authors, Cheng Li.
BMC Bioinformatics, 2011 Mar 11; 12. PMID: 21388547    Free PMC article.
Making sense of cancer genomic data.
Lynda Chin, William C Hahn, Gad Getz, Matthew Meyerson.
Genes Dev, 2011 Mar 17; 25(6). PMID: 21406553    Free PMC article.
Highly Cited. Review.
Activation of miR-31 function in already-established metastases elicits metastatic regression.
Scott Valastyan, Amelia Chang, +2 authors, Robert A Weinberg.
Genes Dev, 2011 Mar 17; 25(6). PMID: 21406558    Free PMC article.
Identification of novel variants of metadherin in breast cancer.
Xianqiang Liu, Ning Zhang, +7 authors, Qifeng Yang.
PLoS One, 2011 Mar 17; 6(3). PMID: 21408129    Free PMC article.
Early breast cancer in the older woman.
Sonal Gandhi, Sunil Verma.
Oncologist, 2011 Mar 19; 16(4). PMID: 21415085    Free PMC article.
Review.
Microarray-based class discovery for molecular classification of breast cancer: analysis of interobserver agreement.
Alan Mackay, Britta Weigelt, +7 authors, Jorge S Reis-Filho.
J Natl Cancer Inst, 2011 Mar 23; 103(8). PMID: 21421860    Free PMC article.
Do two machine-learning based prognostic signatures for breast cancer capture the same biological processes?
Yotam Drier, Eytan Domany.
PLoS One, 2011 Mar 23; 6(3). PMID: 21423753    Free PMC article.
Combining gene signatures improves prediction of breast cancer survival.
Xi Zhao, Einar Andreas Rødland, +6 authors, Ole Christian Lingjærde.
PLoS One, 2011 Mar 23; 6(3). PMID: 21423775    Free PMC article.
Differential expression of prognostic biomarkers between interval and screen-detected breast cancers: does age or family history matter?
Jan T Lowery, Tim Byers, +6 authors, Meenakshi Singh.
Breast Cancer Res Treat, 2011 Mar 25; 129(1). PMID: 21431872    Free PMC article.
Prognostic significance of TRIM24/TIF-1α gene expression in breast cancer.
Monique Chambon, Béatrice Orsetti, +8 authors, Vincent Cavaillès.
Am J Pathol, 2011 Mar 26; 178(4). PMID: 21435435    Free PMC article.
GOBO: gene expression-based outcome for breast cancer online.
Markus Ringnér, Erik Fredlund, +2 authors, Johan Staaf.
PLoS One, 2011 Mar 30; 6(3). PMID: 21445301    Free PMC article.
Highly Cited.
Gene expression signature-based prognostic risk score in gastric cancer.
Jae Yong Cho, Jae Yun Lim, +13 authors, Ju-Seog Lee.
Clin Cancer Res, 2011 Mar 31; 17(7). PMID: 21447720    Free PMC article.
Highly Cited.
E2F1 and KIAA0191 expression predicts breast cancer patient survival.
Robin M Hallett, John A Hassell.
BMC Res Notes, 2011 Apr 02; 4. PMID: 21453498    Free PMC article.
Signaling pathways in breast cancer metastasis - novel insights from functional genomics.
Mario Andres Blanco, Yibin Kang.
Breast Cancer Res, 2011 Apr 05; 13(2). PMID: 21457525    Free PMC article.
Review.
Design and multiseries validation of a web-based gene expression assay for predicting breast cancer recurrence and patient survival.
Ryan K Van Laar.
J Mol Diagn, 2011 Apr 05; 13(3). PMID: 21458382    Free PMC article.
Identification of SERPINA1 as single marker for papillary thyroid carcinoma through microarray meta analysis and quantification of its discriminatory power in independent validation.
Klemens Vierlinger, Markus H Mansfeld, +3 authors, Friedrich Leisch.
BMC Med Genomics, 2011 Apr 08; 4. PMID: 21470421    Free PMC article.
Mass spectrometric characterization of protein structure details refines the proteome signature for invasive ductal breast carcinoma.
Claudia Röwer, Cornelia Koy, +4 authors, Michael O Glocker.
J Am Soc Mass Spectrom, 2011 Apr 08; 22(3). PMID: 21472563
Human cancer classification: a systems biology- based model integrating morphology, cancer stem cells, proteomics, and genomics.
Halliday A Idikio.
J Cancer, 2011 Apr 12; 2. PMID: 21479129    Free PMC article.
A signature of immune function genes associated with recurrence-free survival in breast cancer patients.
Maria Libera Ascierto, Maciej Kmieciak, +10 authors, Masoud H Manjili.
Breast Cancer Res Treat, 2011 Apr 12; 131(3). PMID: 21479927    Free PMC article.
Topology based data analysis identifies a subgroup of breast cancers with a unique mutational profile and excellent survival.
Monica Nicolau, Arnold J Levine, Gunnar Carlsson.
Proc Natl Acad Sci U S A, 2011 Apr 13; 108(17). PMID: 21482760    Free PMC article.
CAERUS: predicting CAncER oUtcomeS using relationship between protein structural information, protein networks, gene expression data, and mutation data.
Kelvin Xi Zhang, B F Francis Ouellette.
PLoS Comput Biol, 2011 Apr 13; 7(3). PMID: 21483478    Free PMC article.
Breast cancer at bone metastatic sites: recent discoveries and treatment targets.
Osama Hussein, Svetlana V Komarova.
J Cell Commun Signal, 2011 Apr 13; 5(2). PMID: 21484191    Free PMC article.
On the C-statistics for evaluating overall adequacy of risk prediction procedures with censored survival data.
Hajime Uno, Tianxi Cai, +2 authors, L J Wei.
Stat Med, 2011 Apr 13; 30(10). PMID: 21484848    Free PMC article.
Highly Cited.
Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization.
Kuo-Jang Kao, Kai-Ming Chang, Hui-Chi Hsu, Andrew T Huang.
BMC Cancer, 2011 Apr 20; 11. PMID: 21501481    Free PMC article.
Highly Cited.
Graphical procedures for evaluating overall and subject-specific incremental values from new predictors with censored event time data.
Hajime Uno, Tianxi Cai, Lu Tian, L J Wei.
Biometrics, 2011 Apr 21; 67(4). PMID: 21504421    Free PMC article.
Preclinical strategies to define predictive biomarkers for therapeutically relevant cancer subtypes.
Marina Pajic, Christopher J Scarlett, +2 authors, Andrew V Biankin.
Hum Genet, 2011 Apr 26; 130(1). PMID: 21516344
Review.
An imbalance in progenitor cell populations reflects tumour progression in breast cancer primary culture models.
Simona Donatello, Lance Hudson, +8 authors, Ann M Hopkins.
J Exp Clin Cancer Res, 2011 Apr 28; 30. PMID: 21521500    Free PMC article.
Metastasis-suppressor genes in clinical practice: lost in translation?
Alexander N Shoushtari, Russell Z Szmulewitz, Carrie W Rinker-Schaeffer.
Nat Rev Clin Oncol, 2011 Apr 28; 8(6). PMID: 21522123
Review.
Sequential interim analyses of survival data in DNA microarray experiments.
Andreas Leha, Tim Beissbarth, Klaus Jung.
BMC Bioinformatics, 2011 Apr 30; 12. PMID: 21527044    Free PMC article.
Estrogen and insulin-like growth factor-I (IGF-I) independently down-regulate critical repressors of breast cancer growth.
Angelo J Casa, Adam S Potter, +9 authors, Adrian V Lee.
Breast Cancer Res Treat, 2011 May 05; 132(1). PMID: 21541704    Free PMC article.
Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications.
Taru A Muranen, Dario Greco, +7 authors, Heli Nevanlinna.
Breast Cancer Res, 2011 May 06; 13(5). PMID: 21542898    Free PMC article.
Elastic SCAD as a novel penalization method for SVM classification tasks in high-dimensional data.
Natalia Becker, Grischa Toedt, Peter Lichter, Axel Benner.
BMC Bioinformatics, 2011 May 11; 12. PMID: 21554689    Free PMC article.
Solving the puzzle of metastasis: the evolution of cell migration in neoplasms.
Jun Chen, Kathleen Sprouffske, Qihong Huang, Carlo C Maley.
PLoS One, 2011 May 11; 6(4). PMID: 21556134    Free PMC article.
Growth factor receptors and apoptosis regulators: signaling pathways, prognosis, chemosensitivity and treatment outcomes of breast cancer.
Siddik Sarkar, Mahitosh Mandal.
Breast Cancer (Auckl), 2009 Jan 01; 3. PMID: 21556249    Free PMC article.
Prognostic utility of HOXB13:IL17BR and molecular grade index in early-stage breast cancer patients from the Stockholm trial.
P-L Jerevall, X-J Ma, +9 authors, O Stål.
Br J Cancer, 2011 May 12; 104(11). PMID: 21559019    Free PMC article.
Receptor activator of NF-kB (RANK) expression in primary tumors associates with bone metastasis occurrence in breast cancer patients.
Daniele Santini, Gaia Schiavon, +16 authors, Giuseppe Tonini.
PLoS One, 2011 May 12; 6(4). PMID: 21559440    Free PMC article.
A comparison of machine learning techniques for survival prediction in breast cancer.
Leonardo Vanneschi, Antonella Farinaccio, +3 authors, Mario Giacobini.
BioData Min, 2011 May 17; 4. PMID: 21569330    Free PMC article.
MicroRNA sequence and expression analysis in breast tumors by deep sequencing.
Thalia A Farazi, Hugo M Horlings, +13 authors, Thomas Tuschl.
Cancer Res, 2011 May 19; 71(13). PMID: 21586611    Free PMC article.
Highly Cited.
A multimarker QPCR-based platform for the detection of circulating tumour cells in patients with early-stage breast cancer.
T J Molloy, L A Devriese, +5 authors, L J van't Veer.
Br J Cancer, 2011 May 19; 104(12). PMID: 21587256    Free PMC article.
When tumor suppressor TGFβ meets the HER2 (ERBB2) oncogene.
Amy Chow, Carlos L Arteaga, Shizhen Emily Wang.
J Mammary Gland Biol Neoplasia, 2011 May 19; 16(2). PMID: 21590373    Free PMC article.
Review.
Identification of prognostic molecular features in the reactive stroma of human breast and prostate cancer.
Anne Planche, Marina Bacac, +4 authors, Ivan Stamenkovic.
PLoS One, 2011 May 26; 6(5). PMID: 21611158    Free PMC article.
A proposal: a comprehensive platform to characterize tumors in Chinese and improve success in cancer drug discovery and development.
Pearl S Huang, Peter T Ho, Kang Zhang.
Chin J Cancer, 2011 Jun 02; 30(6). PMID: 21627857    Free PMC article.
The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors.
Lauren L C Marotta, Vanessa Almendro, +25 authors, Kornelia Polyak.
J Clin Invest, 2011 Jun 03; 121(7). PMID: 21633165    Free PMC article.
Highly Cited.
Acidic nuclear phosphoprotein 32kDa (ANP32)B-deficient mouse reveals a hierarchy of ANP32 importance in mammalian development.
Patrick T Reilly, Samia Afzal, +9 authors, Tak Wah Mak.
Proc Natl Acad Sci U S A, 2011 Jun 04; 108(25). PMID: 21636789    Free PMC article.
The Functional Crosstalk between HER2 Tyrosine Kinase and TGF-β Signaling in Breast Cancer Malignancy.
Shizhen Emily Wang.
J Signal Transduct, 2011 Jun 04; 2011. PMID: 21637380    Free PMC article.
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters.
Tiffany Hung, Yulei Wang, +19 authors, Howard Y Chang.
Nat Genet, 2011 Jun 07; 43(7). PMID: 21642992    Free PMC article.
Highly Cited.
Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9.
Antoine Dufour, Nicole S Sampson, +8 authors, Jian Cao.
Cancer Res, 2011 Jun 08; 71(14). PMID: 21646471    Free PMC article.
Domain and functional analysis of a novel breast tumor suppressor protein, SCUBE2.
Yuh-Charn Lin, Chun-Chuan Chen, Chien-Jui Cheng, Ruey-Bing Yang.
J Biol Chem, 2011 Jun 10; 286(30). PMID: 21652720    Free PMC article.
Emerging tactical strategies for fighting the war on cancer based on the genetic landscape.
Peter D Burbelo, Kathryn H Ching, Kathleen E Bren, Michael J Iadarola.
Am J Transl Res, 2011 Jun 10; 3(3). PMID: 21654880    Free PMC article.
Right-side and left-side colon cancer follow different pathways to relapse.
Kerry M Bauer, Amanda B Hummon, Steven Buechler.
Mol Carcinog, 2011 Jun 10; 51(5). PMID: 21656576    Free PMC article.
Combined genomic and phenotype screening reveals secretory factor SPINK1 as an invasion and survival factor associated with patient prognosis in breast cancer.
Wendy Weijia Soon, Lance David Miller, +7 authors, Edison T Liu.
EMBO Mol Med, 2011 Jun 10; 3(8). PMID: 21656687    Free PMC article.
Global profiling of signaling networks: study of breast cancer stem cells and potential regulation.
Hongxia Wang, Mingzhu Huang, David Y Zhang, Fengchun Zhang.
Oncologist, 2011 Jun 15; 16(7). PMID: 21665913    Free PMC article.
Notch1 inhibition alters the CD44hi/CD24lo population and reduces the formation of brain metastases from breast cancer.
Patricia M McGowan, Carmen Simedrea, +5 authors, Ann F Chambers.
Mol Cancer Res, 2011 Jun 15; 9(7). PMID: 21665937    Free PMC article.
Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse.
J Chuck Harrell, Aleix Prat, +6 authors, Charles M Perou.
Breast Cancer Res Treat, 2011 Jun 15; 132(2). PMID: 21671017    Free PMC article.
Highly Cited.
A functional in vivo screen for regulators of tumor progression identifies HOXB2 as a regulator of tumor growth in breast cancer.
Pamela J Boimel, Cristian Cruz, Jeffrey E Segall.
Genomics, 2011 Jun 16; 98(3). PMID: 21672623    Free PMC article.
Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence.
James L Chen, Jianrong Li, Walter M Stadler, Yves A Lussier.
J Am Med Inform Assoc, 2011 Jun 16; 18(4). PMID: 21672909    Free PMC article.
KIAA0101 interacts with BRCA1 and regulates centrosome number.
Zeina Kais, Sanford H Barsky, +7 authors, Jeffrey D Parvin.
Mol Cancer Res, 2011 Jun 16; 9(8). PMID: 21673012    Free PMC article.
Clinical relevance of DNA microarray analyses using archival formalin-fixed paraffin-embedded breast cancer specimens.
Al Muktafi Sadi, Dong-Yu Wang, +4 authors, Wey L Leong.
BMC Cancer, 2011 Jun 18; 11. PMID: 21679412    Free PMC article.
Towards systematic functional characterization of cancer genomes.
Jesse S Boehm, William C Hahn.
Nat Rev Genet, 2011 Jun 18; 12(7). PMID: 21681210
Review.
A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers.
Bryan T Hennessy, Yiling Lu, +18 authors, Gordon B Mills.
Clin Proteomics, 2011 Jun 22; 6(4). PMID: 21691416    Free PMC article.
Highly Cited.
Deregulation upon DNA damage revealed by joint analysis of context-specific perturbation data.
Ewa Szczurek, Florian Markowetz, +3 authors, Martin Vingron.
BMC Bioinformatics, 2011 Jun 23; 12. PMID: 21693013    Free PMC article.
Gene expression analysis characterizes antemortem stress and has implications for establishing cause of death.
David Jardine, Leanne Cornel, Mary Emond.
Physiol Genomics, 2011 Jun 23; 43(16). PMID: 21693618    Free PMC article.
Impact of established prognostic factors and molecular subtype in very young breast cancer patients: pooled analysis of four EORTC randomized controlled trials.
Jos A van der Hage, J Sven D Mieog, +3 authors, Marc J van de Vijver.
Breast Cancer Res, 2011 Jun 28; 13(3). PMID: 21699739    Free PMC article.
Protein arginine methyltransferase 5 accelerates tumor growth by arginine methylation of the tumor suppressor programmed cell death 4.
Matthew A Powers, Marta M Fay, +2 authors, Katharine S Ullman.
Cancer Res, 2011 Jun 28; 71(16). PMID: 21700716    Free PMC article.
Expression of endoplasmic reticulum stress proteins is a candidate marker of brain metastasis in both ErbB-2+ and ErbB-2- primary breast tumors.
Rebeca Sanz-Pamplona, Ramón Aragüés, +12 authors, Angels Sierra.
Am J Pathol, 2011 Jun 29; 179(2). PMID: 21708117    Free PMC article.
Systematic bias in genomic classification due to contaminating non-neoplastic tissue in breast tumor samples.
Fathi Elloumi, Zhiyuan Hu, +4 authors, Melissa A Troester.
BMC Med Genomics, 2011 Jul 02; 4. PMID: 21718502    Free PMC article.
Functional and prognostic relevance of the homeobox protein MSX2 in malignant melanoma.
G Gremel, D Ryan, +11 authors, W M Gallagher.
Br J Cancer, 2011 Jul 07; 105(4). PMID: 21730974    Free PMC article.
Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas.
Gema Moreno-Bueno, Fernando Salvador, +14 authors, Amparo Cano.
EMBO Mol Med, 2011 Jul 07; 3(9). PMID: 21732535    Free PMC article.
Global microRNA expression profiling identifies MiR-210 associated with tumor proliferation, invasion and poor clinical outcome in breast cancer.
Françoise Rothé, Michail Ignatiadis, +9 authors, Christos Sotiriou.
PLoS One, 2011 Jul 09; 6(6). PMID: 21738599    Free PMC article.
Highly Cited.
Proinvasion metastasis drivers in early-stage melanoma are oncogenes.
Kenneth L Scott, Cristina Nogueira, +19 authors, Lynda Chin.
Cancer Cell, 2011 Jul 12; 20(1). PMID: 21741599    Free PMC article.
Migration of MDA-MB-231 breast cancer cells depends on the availability of exogenous lipids and cholesterol esterification.
Caryl J Antalis, Aki Uchida, Kimberly K Buhman, Rafat A Siddiqui.
Clin Exp Metastasis, 2011 Jul 12; 28(8). PMID: 21744083
Genomic biomarkers in predictive medicine: an interim analysis.
Richard Simon.
EMBO Mol Med, 2011 Jul 12; 3(8). PMID: 21744497    Free PMC article.
Review.
Engagement of I-branching {beta}-1, 6-N-acetylglucosaminyltransferase 2 in breast cancer metastasis and TGF-{beta} signaling.
Haijun Zhang, Fanyan Meng, +5 authors, Guojun Wu.
Cancer Res, 2011 Jul 14; 71(14). PMID: 21750175    Free PMC article.
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Richard Possemato, Kevin M Marks, +24 authors, David M Sabatini.
Nature, 2011 Jul 16; 476(7360). PMID: 21760589    Free PMC article.
Highly Cited.
mRNA levels in control rat liver display strain-specific, hereditary, and AHR-dependent components.
Paul C Boutros, Ivy D Moffat, Allan B Okey, Raimo Pohjanvirta.
PLoS One, 2011 Jul 16; 6(7). PMID: 21760882    Free PMC article.
Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer.
K Kim, G Chadalapaka, +6 authors, S Safe.
Oncogene, 2011 Jul 19; 31(8). PMID: 21765466    Free PMC article.
Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models.
Georg Feldmann, Anjali Mishra, +14 authors, Barry D Nelkin.
Cancer Biol Ther, 2011 Jul 20; 12(7). PMID: 21768779    Free PMC article.
A simple method for assigning genomic grade to individual breast tumours.
Kristian Wennmalm, Jonas Bergh.
BMC Cancer, 2011 Jul 23; 11. PMID: 21777443    Free PMC article.
Kinome expression profiling and prognosis of basal breast cancers.
Renaud Sabatier, Pascal Finetti, +7 authors, François Bertucci.
Mol Cancer, 2011 Jul 23; 10. PMID: 21777462    Free PMC article.
Prognostic and Predictive Markers for Treatment Decisions in Early Breast Cancer.
Elmar Stickeler.
Breast Care (Basel), 2011 Jul 23; 6(3). PMID: 21779224    Free PMC article.
Identification of the YES1 Kinase as a Therapeutic Target in Basal-Like Breast Cancers.
Erhan Bilal, Gabriela Alexe, +6 authors, Gyan Bhanot.
Genes Cancer, 2011 Jul 23; 1(10). PMID: 21779430    Free PMC article.
Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer.
Rebecca Roylance, David Endesfelder, +12 authors, Charles Swanton.
Cancer Epidemiol Biomarkers Prev, 2011 Jul 26; 20(10). PMID: 21784954    Free PMC article.
Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction.
Pierre-Emmanuel Colombo, Fernanda Milanezi, Britta Weigelt, Jorge S Reis-Filho.
Breast Cancer Res, 2011 Jul 27; 13(3). PMID: 21787441    Free PMC article.
Review.
Predictive and prognostic molecular markers for cancer medicine.
Sunali Mehta, Andrew Shelling, +4 authors, Cristin Print.
Ther Adv Med Oncol, 2010 Mar 01; 2(2). PMID: 21789130    Free PMC article.
Inhibition of matrix metalloproteinase 14 (MMP-14)-mediated cancer cell migration.
Kevin Zarrabi, Antoine Dufour, +7 authors, Jian Cao.
J Biol Chem, 2011 Jul 29; 286(38). PMID: 21795678    Free PMC article.
Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response.
Qiyuan Li, Aron C Eklund, +8 authors, Zoltan Szallasi.
BMC Bioinformatics, 2011 Jul 30; 12. PMID: 21798043    Free PMC article.
A serum protein profile predictive of the resistance to neoadjuvant chemotherapy in advanced breast cancers.
Seok-Won Hyung, Min Young Lee, +12 authors, Dong-Young Noh.
Mol Cell Proteomics, 2011 Jul 30; 10(10). PMID: 21799047    Free PMC article.
ChIP-seq defined genome-wide map of TGFβ/SMAD4 targets: implications with clinical outcome of ovarian cancer.
Brian A Kennedy, Daniel E Deatherage, +5 authors, Victor X Jin.
PLoS One, 2011 Jul 30; 6(7). PMID: 21799915    Free PMC article.
Induction of stable drug resistance in human breast cancer cells using a combinatorial zinc finger transcription factor library.
Jeongeun Lee, Andrew S Hirsh, +9 authors, Dennis C Sgroi.
PLoS One, 2011 Aug 06; 6(7). PMID: 21818254    Free PMC article.
Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2.
Traci R Lyons, Jenean O'Brien, +6 authors, Pepper Schedin.
Nat Med, 2011 Aug 09; 17(9). PMID: 21822285    Free PMC article.
Highly Cited.
18F-fluorodeoxyglucose positron emission tomography optimizes neoadjuvant chemotherapy for primary breast cancer to achieve pathological complete response.
Shigeto Ueda, Toshiaki Saeki, +15 authors, Hiroshi Matsuda.
Int J Clin Oncol, 2011 Aug 11; 17(3). PMID: 21830087
The 70-gene prognostic signature for korean breast cancer patients.
Kuk Young Na, Ku Sang Kim, +7 authors, Yong Sik Jung.
J Breast Cancer, 2011 Aug 19; 14(1). PMID: 21847392    Free PMC article.
Remodeling of purinergic receptor-mediated Ca2+ signaling as a consequence of EGF-induced epithelial-mesenchymal transition in breast cancer cells.
Felicity M Davis, Paraic A Kenny, +6 authors, Gregory R Monteith.
PLoS One, 2011 Aug 19; 6(8). PMID: 21850275    Free PMC article.
Prognostic factors affecting postmastectomy locoregional recurrence in patients with early breast cancer: are intrinsic subtypes effective?
Hakan Mersin, Kaptan Gülben, +4 authors, Sükrü Erdoğan.
World J Surg, 2011 Aug 20; 35(10). PMID: 21853356
Whole genome expression in peripheral-blood samples of workers professionally exposed to polycyclic aromatic hydrocarbons.
Ming-Tsang Wu, Tzu-Chi Lee, +10 authors, Chi-Kung Ho.
Chem Res Toxicol, 2011 Aug 23; 24(10). PMID: 21854004    Free PMC article.
Relationships of ESR1 and XBP1 expression in human breast carcinoma and stromal cells isolated by laser capture microdissection compared to intact breast cancer tissue.
Sarah A Andres, James L Wittliff.
Endocrine, 2011 Aug 23; 40(2). PMID: 21858728
Prognostic and predictive markers in stage II colon cancer: is there a role for gene expression profiling?
Robin K Kelley, Alan P Venook.
Clin Colorectal Cancer, 2011 Aug 24; 10(2). PMID: 21859557    Free PMC article.
Review.
An integrative genomics approach to biomarker discovery in breast cancer.
Chindo Hicks, Rozana Asfour, Antonio Pannuti, Lucio Miele.
Cancer Inform, 2011 Aug 27; 10. PMID: 21869864    Free PMC article.
Systems biology of kidney diseases.
John Cijiang He, Peter Y Chuang, Avi Ma'ayan, Ravi Iyengar.
Kidney Int, 2011 Sep 02; 81(1). PMID: 21881558    Free PMC article.
Review.
GATA3 inhibits lysyl oxidase-mediated metastases of human basal triple-negative breast cancer cells.
I M Chu, A M Michalowski, +7 authors, J E Green.
Oncogene, 2011 Sep 06; 31(16). PMID: 21892208    Free PMC article.
Impact of mammographic screening on the detection of good and poor prognosis breast cancers.
Laura J Esserman, Yiwey Shieh, +8 authors, Laura J van 't Veer.
Breast Cancer Res Treat, 2011 Sep 06; 130(3). PMID: 21892702    Free PMC article.
Review.
Semi-supervised learning improves gene expression-based prediction of cancer recurrence.
Mingguang Shi, Bing Zhang.
Bioinformatics, 2011 Sep 07; 27(21). PMID: 21893520    Free PMC article.
Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer.
Ana M Gonzalez-Angulo, Bryan T Hennessy, +19 authors, Gordon B Mills.
Clin Proteomics, 2011 Sep 13; 8(1). PMID: 21906370    Free PMC article.
Postoperative serum proteomic profiles may predict recurrence-free survival in high-risk primary breast cancer.
Marie-Christine W Gast, Marc Zapatka, +7 authors, Jos H Beijnen.
J Cancer Res Clin Oncol, 2011 Sep 14; 137(12). PMID: 21913038    Free PMC article.
Breast cancer biological subtypes and protein expression predict for the preferential distant metastasis sites: a nationwide cohort study.
Harri Sihto, Johan Lundin, +9 authors, Heikki Joensuu.
Breast Cancer Res, 2011 Sep 15; 13(5). PMID: 21914172    Free PMC article.
High-dimensional bolstered error estimation.
Chao Sima, Ulisses M Braga-Neto, Edward R Dougherty.
Bioinformatics, 2011 Sep 15; 27(21). PMID: 21914630    Free PMC article.
Ischemia caused by time to freezing induces systematic microRNA and mRNA responses in cancer tissue.
Eldrid Borgan, Roy Navon, +6 authors, Anne-Lise Børresen-Dale.
Mol Oncol, 2011 Sep 16; 5(6). PMID: 21917534    Free PMC article.
TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73.
Kang Liu, Shiyun Ling, Weei-Chin Lin.
Mol Cell Biol, 2011 Sep 21; 31(22). PMID: 21930790    Free PMC article.
Suppression of breast tumor growth and metastasis by an engineered transcription factor.
Adriana S Beltran, Angela Russo, +3 authors, Pilar Blancafort.
PLoS One, 2011 Sep 21; 6(9). PMID: 21931769    Free PMC article.
Relationship between quantitative GRB7 RNA expression and recurrence after adjuvant anthracycline chemotherapy in triple-negative breast cancer.
Joseph A Sparano, Lori J Goldstein, +13 authors, Robert Gray.
Clin Cancer Res, 2011 Sep 22; 17(22). PMID: 21933890    Free PMC article.
Breast medical oncologists' use of standard prognostic factors to predict a 21-gene recurrence score.
Arif H Kamal, Charles L Loprinzi, +7 authors, Matthew P Goetz.
Oncologist, 2011 Sep 22; 16(10). PMID: 21934103    Free PMC article.
Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome.
Dana M Brantley-Sieders, Aixiang Jiang, +4 authors, Jin Chen.
PLoS One, 2011 Sep 22; 6(9). PMID: 21935409    Free PMC article.
Clinical implementation of comprehensive strategies to characterize cancer genomes: opportunities and challenges.
Laura E MacConaill, Paul Van Hummelen, Matthew Meyerson, William C Hahn.
Cancer Discov, 2011 Sep 22; 1(4). PMID: 21935500    Free PMC article.
Review.
A new gene expression signature, the ClinicoMolecular Triad Classification, may improve prediction and prognostication of breast cancer at the time of diagnosis.
Dong-Yu Wang, Susan J Done, +3 authors, Wey Liang Leong.
Breast Cancer Res, 2011 Sep 24; 13(5). PMID: 21939527    Free PMC article.
A comprehensive view of nuclear receptor cancer cistromes.
Qianzi Tang, Yiwen Chen, +7 authors, Xiaole Shirley Liu.
Cancer Res, 2011 Sep 24; 71(22). PMID: 21940749    Free PMC article.
Unravelling the complexity of metastasis - molecular understanding and targeted therapies.
Nilay Sethi, Yibin Kang.
Nat Rev Cancer, 2011 Sep 24; 11(10). PMID: 21941285
Highly Cited. Review.
Recent progress and clinical importance on pharmacogenetics in cancer therapy.
Thomas I Peng Soh, Wei Peng Yong, Federico Innocenti.
Clin Chem Lab Med, 2011 Sep 29; 49(10). PMID: 21950596    Free PMC article.
Review.
Discovering biological connections between experimental conditions based on common patterns of differential gene expression.
Adam C Gower, Avrum Spira, Marc E Lenburg.
BMC Bioinformatics, 2011 Sep 29; 12. PMID: 21951600    Free PMC article.
Improving communication of breast cancer recurrence risk.
Noel T Brewer, Alice R Richman, +2 authors, Lisa A Carey.
Breast Cancer Res Treat, 2011 Oct 04; 133(2). PMID: 21964579    Free PMC article.
Insight into the heterogeneity of breast cancer through next-generation sequencing.
Hege G Russnes, Nicholas Navin, James Hicks, Anne-Lise Borresen-Dale.
J Clin Invest, 2011 Oct 04; 121(10). PMID: 21965338    Free PMC article.
Highly Cited. Review.
A clinically relevant gene signature in triple negative and basal-like breast cancer.
Achim Rody, Thomas Karn, +11 authors, Manfred Kaufmann.
Breast Cancer Res, 2011 Oct 08; 13(5). PMID: 21978456    Free PMC article.
Highly Cited.
Protein networks as logic functions in development and cancer.
Janusz Dutkowski, Trey Ideker.
PLoS Comput Biol, 2011 Oct 08; 7(9). PMID: 21980275    Free PMC article.
Coexisting ductal carcinoma in situ independently predicts lower tumor aggressiveness in node-positive luminal breast cancer.
H Wong, S Lau, +6 authors, T Yau.
Med Oncol, 2011 Oct 11; 29(3). PMID: 21983862
Tailoring therapy for locally advanced breast cancer using molecular profiles: are we there yet?
Christopher Fosker, Julian W Adlard, Abeer Shaaban.
Drugs, 2011 Oct 12; 71(15). PMID: 21985164
Adjuvant trastuzumab in HER2-positive breast cancer.
Dennis Slamon, Wolfgang Eiermann, +21 authors, Breast Cancer International Research Group.
N Engl J Med, 2011 Oct 14; 365(14). PMID: 21991949    Free PMC article.
Highly Cited.
Identifying cancer biomarkers by network-constrained support vector machines.
Li Chen, Jianhua Xuan, +2 authors, Yue Wang.
BMC Syst Biol, 2011 Oct 14; 5. PMID: 21992556    Free PMC article.
[Research advances of artemin].
Guangsu Xun, Fengjie Guo, Zhigang Li, Qinghua Zhou.
Zhongguo Fei Ai Za Zhi, 2011 Oct 20; 14(10). PMID: 22008109    Free PMC article.
Review.
Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes.
Yoko S DeRose, Guoying Wang, +12 authors, Alana L Welm.
Nat Med, 2011 Oct 25; 17(11). PMID: 22019887    Free PMC article.
Highly Cited.
Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity.
Nicolas Léveillé, Ran Elkon, +11 authors, Reuven Agami.
Nat Commun, 2011 Oct 27; 2. PMID: 22027593    Free PMC article.
A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer.
Wendy L Allen, Leanne Stevenson, +8 authors, Patrick G Johnston.
Mol Cancer Ther, 2011 Oct 27; 11(1). PMID: 22027693    Free PMC article.
Most random gene expression signatures are significantly associated with breast cancer outcome.
David Venet, Jacques E Dumont, Vincent Detours.
PLoS Comput Biol, 2011 Oct 27; 7(10). PMID: 22028643    Free PMC article.
Highly Cited.
Clinical trials in the era of personalized oncology.
Michael L Maitland, Richard L Schilsky.
CA Cancer J Clin, 2011 Oct 29; 61(6). PMID: 22034206    Free PMC article.
Stepwise classification of cancer samples using clinical and molecular data.
Askar Obulkasim, Gerrit A Meijer, Mark A van de Wiel.
BMC Bioinformatics, 2011 Nov 01; 12. PMID: 22034839    Free PMC article.
High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer.
Sandro Santagata, Rong Hu, +8 authors, Tan A Ince.
Proc Natl Acad Sci U S A, 2011 Nov 02; 108(45). PMID: 22042860    Free PMC article.
Highly Cited.
Emerging drug discovery approaches for selective targeting of "precursor" metastatic breast cancer cells: highlights and perspectives.
Moulay Aalaoui-Jamali, Krikor Bijian, Gerald Batist.
Am J Transl Res, 2011 Nov 03; 3(5). PMID: 22046485    Free PMC article.
Signaling pathway-based identification of extensive prognostic gene signatures for lung adenocarcinoma.
Ying-Wooi Wan, David G Beer, Nancy Lan Guo.
Lung Cancer, 2011 Nov 04; 76(1). PMID: 22047960    Free PMC article.
The combined expression of metaplasia biomarkers predicts the prognosis of gastric cancer.
Yun-Suhk Suh, Hyuk-Joon Lee, +5 authors, Woo Ho Kim.
Ann Surg Oncol, 2011 Nov 04; 19(4). PMID: 22048633    Free PMC article.
Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival.
Victor J Weigman, Hann-Hsiang Chao, +11 authors, Charles M Perou.
Breast Cancer Res Treat, 2011 Nov 04; 133(3). PMID: 22048815    Free PMC article.
Local sparse bump hunting reveals molecular heterogeneity of colon tumors.
Jean-Eudes Dazard, J Sunil Rao, Sanford Markowitz.
Stat Med, 2011 Nov 05; 31(11-12). PMID: 22052459    Free PMC article.
Selective voting in convex-hull ensembles improves classification accuracy.
Ralph L Kodell, Chuanlei Zhang, Eric R Siegel, Radhakrishnan Nagarajan.
Artif Intell Med, 2011 Nov 09; 54(3). PMID: 22064044    Free PMC article.
Molecular characterisation of formalin-fixed paraffin-embedded (FFPE) breast tumour specimens using a custom 512-gene breast cancer bead array-based platform.
M Abramovitz, B G Barwick, +8 authors, B Leyland-Jones.
Br J Cancer, 2011 Nov 10; 105(10). PMID: 22067903    Free PMC article.
Telomere length variation in normal epithelial cells adjacent to tumor: potential biomarker for breast cancer local recurrence.
Xin Zhou, Alan K Meeker, +5 authors, Yun-Ling Zheng.
Carcinogenesis, 2011 Nov 11; 33(1). PMID: 22072619    Free PMC article.
Basal breast cancer: a complex and deadly molecular subtype.
F Bertucci, P Finetti, D Birnbaum.
Curr Mol Med, 2011 Nov 16; 12(1). PMID: 22082486    Free PMC article.
Review.
External validation of Adjuvant! Online breast cancer prognosis tool. Prioritising recommendations for improvement.
David Hajage, Yann de Rycke, +11 authors, Fabien Reyal.
PLoS One, 2011 Nov 17; 6(11). PMID: 22087319    Free PMC article.
Potential responders to FOLFOX therapy for colorectal cancer by Random Forests analysis.
S Tsuji, Y Midorikawa, +5 authors, H Aburatani.
Br J Cancer, 2011 Nov 19; 106(1). PMID: 22095227    Free PMC article.
The colony-stimulating factor-1 (CSF-1) receptor sustains ERK1/2 activation and proliferation in breast cancer cell lines.
Andrea Morandi, Valentina Barbetti, +2 authors, Elisabetta Rovida.
PLoS One, 2011 Nov 19; 6(11). PMID: 22096574    Free PMC article.
Biologic characteristics of premalignant breast disease.
Kimberly Cole, Maria Tabernero, Karen S Anderson.
Cancer Biomark, 2011 Nov 25; 9(1-6). PMID: 22112476    Free PMC article.
M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells.
Ariel F Castro, Tania Campos, +4 authors, Lawrence A Quilliam.
J Cell Biochem, 2011 Nov 29; 113(4). PMID: 22121046    Free PMC article.
PBX1 genomic pioneer function drives ERα signaling underlying progression in breast cancer.
Luca Magnani, Elizabeth B Ballantyne, Xiaoyang Zhang, Mathieu Lupien.
PLoS Genet, 2011 Nov 30; 7(11). PMID: 22125492    Free PMC article.
Lack of sufficiently strong informative features limits the potential of gene expression analysis as predictive tool for many clinical classification problems.
Kenneth R Hess, Caimiao Wei, +3 authors, Lajos Pusztai.
BMC Bioinformatics, 2011 Dec 03; 12. PMID: 22132775    Free PMC article.
TRIM29 functions as a tumor suppressor in nontumorigenic breast cells and invasive ER+ breast cancer.
Jin Liu, Bryan Welm, +2 authors, Philip S Bernard.
Am J Pathol, 2011 Dec 06; 180(2). PMID: 22138580    Free PMC article.
Identification of prognostic genes for recurrent risk prediction in triple negative breast cancer patients in Taiwan.
Lee H Chen, Wen-Hung Kuo, +7 authors, King-Jen Chang.
PLoS One, 2011 Dec 06; 6(11). PMID: 22140552    Free PMC article.
Practical implications of gene-expression-based assays for breast oncologists.
Aleix Prat, Matthew J Ellis, Charles M Perou.
Nat Rev Clin Oncol, 2011 Dec 07; 9(1). PMID: 22143140    Free PMC article.
Highly Cited. Review.
Global gene expression profiling in mouse plasma cell tumor precursor and bystander cells reveals potential intervention targets for plasma cell neoplasia.
Jason LeGrand, Eun Sung Park, +7 authors, J Frederic Mushinski.
Blood, 2011 Dec 08; 119(4). PMID: 22147894    Free PMC article.
Next-generation sequencing for cancer diagnostics: a practical perspective.
Cliff Meldrum, Maria A Doyle, Richard W Tothill.
Clin Biochem Rev, 2011 Dec 08; 32(4). PMID: 22147957    Free PMC article.
Highly Cited.
Optimized application of penalized regression methods to diverse genomic data.
Levi Waldron, Melania Pintilie, +3 authors, Igor Jurisica.
Bioinformatics, 2011 Dec 14; 27(24). PMID: 22156367    Free PMC article.
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.
Jessica D Kessler, Kristopher T Kahle, +24 authors, Thomas F Westbrook.
Science, 2011 Dec 14; 335(6066). PMID: 22157079    Free PMC article.
Highly Cited.
A simple but highly effective approach to evaluate the prognostic performance of gene expression signatures.
Maud H W Starmans, Glenn Fung, +2 authors, Philippe Lambin.
PLoS One, 2011 Dec 14; 6(12). PMID: 22163293    Free PMC article.
Selecting a single model or combining multiple models for microarray-based classifier development?--a comparative analysis based on large and diverse datasets generated from the MAQC-II project.
Minjun Chen, Leming Shi, +3 authors, Weida Tong.
BMC Bioinformatics, 2011 Dec 23; 12 Suppl 10. PMID: 22166133    Free PMC article.
Antibody colocalization microarray: a scalable technology for multiplex protein analysis in complex samples.
M Pla-Roca, R F Leulmi, +8 authors, D Juncker.
Mol Cell Proteomics, 2011 Dec 16; 11(4). PMID: 22171321    Free PMC article.
Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer.
Yun-Yong Park, Kyounghyun Kim, +11 authors, Ju-Seog Lee.
EMBO Mol Med, 2011 Dec 17; 4(1). PMID: 22174013    Free PMC article.
Survival models with preclustered gene groups as covariates.
Kai Kammers, Michel Lang, +2 authors, Jörg Rahnenführer.
BMC Bioinformatics, 2011 Dec 20; 12. PMID: 22177110    Free PMC article.
Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors.
Jesper B Andersen, Bart Spee, +9 authors, Snorri S Thorgeirsson.
Gastroenterology, 2011 Dec 20; 142(4). PMID: 22178589    Free PMC article.
Highly Cited.
Early developments in gene-expression profiling of breast tumors: potential for increasing black-white patient disparities in breast cancer outcomes?
Donna H Odierna, Aimee Afable-Munsuz, +5 authors, Ninez A Ponce.
Per Med, 2011 Dec 23; 8(6). PMID: 22190978    Free PMC article.
Characterization of uncertainty in the classification of multivariate assays: application to PAM50 centroid-based genomic predictors for breast cancer treatment plans.
Mark Tw Ebbert, Roy Rl Bastien, +6 authors, Julio C Facelli.
J Clin Bioinforma, 2011 Dec 27; 1. PMID: 22196354    Free PMC article.
Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).
Laura J Esserman, Donald A Berry, +32 authors, I-SPY 1 TRIAL Investigators.
Breast Cancer Res Treat, 2011 Dec 27; 132(3). PMID: 22198468    Free PMC article.
Highly Cited.
Potential utility of an expression array signature for predicting anthracycline responsiveness or resistance.
Michael F Press, Michael A Gordon, Dennis J Slamon.
J Clin Oncol, 2011 Dec 29; 30(4). PMID: 22203766    Free PMC article.
SLC22A5/OCTN2 expression in breast cancer is induced by estrogen via a novel intronic estrogen-response element (ERE).
Chunyu Wang, Ivan P Uray, +2 authors, Powel H Brown.
Breast Cancer Res Treat, 2012 Jan 04; 134(1). PMID: 22212555    Free PMC article.
Correlated immunohistochemical and cytological assays for the prediction of hematogenous dissemination of breast cancer.
Maja H Oktay, Frank B Gertler, +3 authors, Joan G Jones.
J Histochem Cytochem, 2012 Jan 05; 60(3). PMID: 22215635    Free PMC article.
Review.
'Omic approaches to preventing or managing metastatic breast cancer.
Obi L Griffith, Joe W Gray.
Breast Cancer Res, 2012 Jan 06; 13(6). PMID: 22216753    Free PMC article.
Review.
Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures.
Thomas Karn, Lajos Pusztai, +12 authors, Achim Rody.
PLoS One, 2012 Jan 06; 6(12). PMID: 22220191    Free PMC article.
Characterization and clinical evaluation of CD10+ stroma cells in the breast cancer microenvironment.
Christine Desmedt, Samira Majjaj, +18 authors, Christos Sotiriou.
Clin Cancer Res, 2012 Jan 12; 18(4). PMID: 22235100    Free PMC article.
Global gene expression analysis of the interaction between cancer cells and osteoblasts to predict bone metastasis in breast cancer.
Michal Rajski, Brigitte Vogel, +2 authors, Martin Buess.
PLoS One, 2012 Jan 12; 7(1). PMID: 22235336    Free PMC article.
Association of HADHA expression with the risk of breast cancer: targeted subset analysis and meta-analysis of microarray data.
Manju Mamtani, Hemant Kulkarni.
BMC Res Notes, 2012 Jan 14; 5. PMID: 22240105    Free PMC article.
Integrated proteomic, transcriptomic, and biological network analysis of breast carcinoma reveals molecular features of tumorigenesis and clinical relapse.
Marcin Imielinski, Sangwon Cha, +3 authors, Dennis C Sgroi.
Mol Cell Proteomics, 2012 Jan 14; 11(6). PMID: 22240506    Free PMC article.
Systems biology approaches to decoding the genome of liver cancer.
Ju-Seog Lee, Ji Hoon Kim, Yun-Yong Park, Gordon B Mills.
Cancer Res Treat, 2012 Jan 17; 43(4). PMID: 22247704    Free PMC article.
Core module biomarker identification with network exploration for breast cancer metastasis.
Ruoting Yang, Bernie J Daigle, Linda R Petzold, Francis J Doyle.
BMC Bioinformatics, 2012 Jan 20; 13. PMID: 22257533    Free PMC article.
A three-gene model to robustly identify breast cancer molecular subtypes.
Benjamin Haibe-Kains, Christine Desmedt, +4 authors, Christos Sotiriou.
J Natl Cancer Inst, 2012 Jan 21; 104(4). PMID: 22262870    Free PMC article.
Highly Cited.
Genome-wide association analysis identifies three new breast cancer susceptibility loci.
Maya Ghoussaini, Olivia Fletcher, +184 authors, Douglas F Easton.
Nat Genet, 2012 Jan 24; 44(3). PMID: 22267197    Free PMC article.
Highly Cited.
Gene expression profiling: changing face of breast cancer classification and management.
Robert Wesolowski, Bhuvaneswari Ramaswamy.
Gene Expr, 2012 Jan 25; 15(3). PMID: 22268293    Free PMC article.
Review.
Post-genomic clinical trials: the perspective of ACGT.
N Graf, C Desmedt, +6 authors, M Tsiknakis.
Ecancermedicalscience, 2008 Jan 01; 2. PMID: 22275963    Free PMC article.
Decreased autocrine EGFR signaling in metastatic breast cancer cells inhibits tumor growth in bone and mammary fat pad.
Nicole K Nickerson, Khalid S Mohammad, +4 authors, John Foley.
PLoS One, 2012 Jan 26; 7(1). PMID: 22276166    Free PMC article.
The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer.
A L Smith, R Iwanaga, +4 authors, H L Ford.
Oncogene, 2012 Jan 31; 31(50). PMID: 22286770    Free PMC article.
Highly Cited.
Single sample expression-anchored mechanisms predict survival in head and neck cancer.
Xinan Yang, Kelly Regan, +6 authors, Yves A Lussier.
PLoS Comput Biol, 2012 Feb 01; 8(1). PMID: 22291585    Free PMC article.
Shifting from population-wide to personalized cancer prognosis with microarrays.
Li Shao, Xiaohui Fan, +7 authors, Weida Tong.
PLoS One, 2012 Feb 02; 7(1). PMID: 22295060    Free PMC article.
Differential gene expression in primary breast tumors associated with lymph node metastasis.
Rachel E Ellsworth, Lori A Field, +3 authors, Craig D Shriver.
Int J Breast Cancer, 2012 Feb 02; 2011. PMID: 22295210    Free PMC article.
Bromodomain-Containing Protein 4: A Dynamic Regulator of Breast Cancer Metastasis through Modulation of the Extracellular Matrix.
Jude Alsarraj, Kent W Hunter.
Int J Breast Cancer, 2012 Feb 02; 2012. PMID: 22295248    Free PMC article.
Do we need biomarkers to predict the benefit of adding adjuvant taxanes for treatment of breast cancer?
José Pérez-García, Javier Cortés.
Breast Cancer Res, 2012 Feb 03; 14(1). PMID: 22297134    Free PMC article.
When one and one gives more than two: challenges and opportunities of integrative omics.
Hyungwon Choi, Norman Pavelka.
Front Genet, 2012 Feb 04; 2. PMID: 22303399    Free PMC article.
A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer.
Benjamin T Spike, Dannielle D Engle, +3 authors, Geoffrey M Wahl.
Cell Stem Cell, 2012 Feb 07; 10(2). PMID: 22305568    Free PMC article.
Highly Cited.
Integrated cross-species transcriptional network analysis of metastatic susceptibility.
Ying Hu, Gang Wu, +4 authors, Kent W Hunter.
Proc Natl Acad Sci U S A, 2012 Feb 07; 109(8). PMID: 22308418    Free PMC article.
Determining PTEN functional status by network component deduced transcription factor activities.
Linh M Tran, Chun-Ju Chang, +6 authors, Hong Wu.
PLoS One, 2012 Feb 22; 7(2). PMID: 22347425    Free PMC article.
Time-dependent transcriptional profiling links gene expression to mitogen-activated protein kinase kinase 4 (MKK4)-mediated suppression of omental metastatic colonization.
Russell O Bainer, Jennifer Taylor Veneris, +4 authors, Carrie W Rinker-Schaeffer.
Clin Exp Metastasis, 2012 Feb 22; 29(5). PMID: 22350525    Free PMC article.
Use of non-amplified RNA samples for microarray analysis of gene expression.
Hiroko Sudo, Atsuko Mizoguchi, +2 authors, Satoko Takizawa.
PLoS One, 2012 Feb 23; 7(2). PMID: 22355363    Free PMC article.
A gene signature for predicting outcome in patients with basal-like breast cancer.
Robin M Hallett, Anna Dvorkin-Gheva, Anita Bane, John A Hassell.
Sci Rep, 2012 Feb 23; 2. PMID: 22355741    Free PMC article.
Transcriptomic landscape of breast cancers through mRNA sequencing.
Jeyanthy Eswaran, Dinesh Cyanam, +7 authors, Rakesh Kumar.
Sci Rep, 2012 Feb 23; 2. PMID: 22355776    Free PMC article.
Proteomics of mouse BRCA1-deficient mammary tumors identifies DNA repair proteins with potential diagnostic and prognostic value in human breast cancer.
Marc Warmoes, Janneke E Jaspers, +8 authors, Connie R Jimenez.
Mol Cell Proteomics, 2012 Mar 01; 11(7). PMID: 22366898    Free PMC article.
Evaluation of data integration strategies based on kernel method of clinical and microarray data.
Ary Noviyanto, Ito Wasito.
Bioinformation, 2012 Mar 01; 8(3). PMID: 22368387    Free PMC article.
Decentral gene expression analysis for ER+/Her2- breast cancer: results of a proficiency testing program for the EndoPredict assay.
Carsten Denkert, Ralf Kronenwett, +23 authors, Manfred Dietel.
Virchows Arch, 2012 Mar 01; 460(3). PMID: 22371223    Free PMC article.
The molecular basis of chemoradiosensitivity in rectal cancer: implications for personalized therapies.
Marian Grade, Hendrik A Wolff, Jochen Gaedcke, B Michael Ghadimi.
Langenbecks Arch Surg, 2012 Mar 03; 397(4). PMID: 22382702    Free PMC article.
Review.
A prognostic gene expression profile that predicts circulating tumor cell presence in breast cancer patients.
Timothy J Molloy, Paul Roepman, Bjørn Naume, Laura J van't Veer.
PLoS One, 2012 Mar 03; 7(2). PMID: 22384245    Free PMC article.
Increased efficacy of a dose-dense regimen of neoadjuvant chemotherapy in breast carcinoma: a retrospective analysis.
Bohuslav Melichar, Helena Hornychová, +7 authors, Aleš Ryška.
Med Oncol, 2012 Mar 07; 29(4). PMID: 22392196
ROR1 is expressed in human breast cancer and associated with enhanced tumor-cell growth.
Suping Zhang, Liguang Chen, +7 authors, Thomas J Kipps.
PLoS One, 2012 Mar 10; 7(3). PMID: 22403610    Free PMC article.
Highly Cited.
Hormonal therapy in breast cancer: a model disease for the personalization of cancer care.
Shannon Puhalla, Saveri Bhattacharya, Nancy E Davidson.
Mol Oncol, 2012 Mar 13; 6(2). PMID: 22406404    Free PMC article.
Review.
Analysis of hypermethylation and expression profiles of APC and ATM genes in patients with oral squamous cell carcinoma.
Mohammad Ayub Rigi-Ladiz, Dor Mohammad Kordi-Tamandani, Adam Torkamanzehi.
Clin Epigenetics, 2011 Jan 01; 3. PMID: 22414247    Free PMC article.
Industrial methodology for process verification in research (IMPROVER): toward systems biology verification.
Pablo Meyer, Julia Hoeng, +8 authors, Gustavo Stolovitzky.
Bioinformatics, 2012 Mar 17; 28(9). PMID: 22423044    Free PMC article.
Review.
Patients with positive axillary lymph nodes: how to use genomic assays.
Ruta Rao.
Curr Treat Options Oncol, 2012 Mar 20; 13(2). PMID: 22426945
Gene Selection using a High-Dimensional Regression Model with Microarrays in Cancer Prognostic Studies.
Shuhei Kaneko, Akihiro Hirakawa, Chikuma Hamada.
Cancer Inform, 2012 Mar 24; 11. PMID: 22442625    Free PMC article.
Comparison of the RNA-based EndoPredict multigene test between core biopsies and corresponding surgical breast cancer sections.
Berit Maria Müller, Jan C Brase, +7 authors, Carsten Denkert.
J Clin Pathol, 2012 Mar 27; 65(7). PMID: 22447922    Free PMC article.
Validation study of existing gene expression signatures for anti-TNF treatment in patients with rheumatoid arthritis.
Erik J M Toonen, Christian Gilissen, +10 authors, Marieke J H Coenen.
PLoS One, 2012 Mar 30; 7(3). PMID: 22457743    Free PMC article.
Pharmacogenetics: implementing personalized medicine.
Enrico Mini, Stefania Nobili.
Clin Cases Miner Bone Metab, 2009 Jan 01; 6(1). PMID: 22461093    Free PMC article.
Targeting the insulin-like growth factor receptor: developing biomarkers from gene expression profiling.
David N Boone, Adrian V Lee.
Crit Rev Oncog, 2012 Apr 05; 17(2). PMID: 22471706    Free PMC article.
Review.
CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells.
Akihiro Tsuyada, Amy Chow, +16 authors, Shizhen Emily Wang.
Cancer Res, 2012 Apr 05; 72(11). PMID: 22472119    Free PMC article.
Highly Cited.
Molecular profiling of individual tumor cells by hyperspectral microscopic imaging.
Jonathan W Uhr, Michael L Huebschman, +9 authors, Harold R Garner.
Transl Res, 2012 Apr 17; 159(5). PMID: 22500509    Free PMC article.
Elevated levels of HSF1 indicate a poor prognosis in breast cancer.
Stuart K Calderwood.
Future Oncol, 2012 Apr 21; 8(4). PMID: 22515443    Free PMC article.
The use of classification trees for bioinformatics.
Xiang Chen, Minghui Wang, Heping Zhang.
Wiley Interdiscip Rev Data Min Knowl Discov, 2011 Jan 01; 1(1). PMID: 22523608    Free PMC article.
Triple-negative invasive breast cancer on dynamic contrast-enhanced and diffusion-weighted MR imaging: comparison with other breast cancer subtypes.
Ji Hyun Youk, Eun Ju Son, +2 authors, Eun-Kyung Kim.
Eur Radiol, 2012 Apr 25; 22(8). PMID: 22527371
Molecular signatures from omics data: from chaos to consensus.
Jaeyun Sung, Yuliang Wang, +2 authors, Nathan D Price.
Biotechnol J, 2012 Apr 25; 7(8). PMID: 22528809    Free PMC article.
Review.
Dormancy signatures and metastasis in estrogen receptor positive and negative breast cancer.
Ryung S Kim, Alvaro Avivar-Valderas, +4 authors, Jeffrey E Segall.
PLoS One, 2012 Apr 25; 7(4). PMID: 22530051    Free PMC article.
Predicting glioblastoma prognosis networks using weighted gene co-expression network analysis on TCGA data.
Yang Xiang, Cun-Quan Zhang, Kun Huang.
BMC Bioinformatics, 2012 May 02; 13 Suppl 2. PMID: 22536863    Free PMC article.
Age of 40 years or younger is an independent risk factor for locoregional failure in early breast cancer: a single-institutional analysis in saudi arabia.
Volker Rudat, Hamdan El-Sweilmeen, +5 authors, Saleh Altuwaijri.
J Oncol, 2012 May 01; 2012. PMID: 22545048    Free PMC article.
Gene selection using iterative feature elimination random forests for survival outcomes.
Herbert Pang, Stephen L George, Ken Hui, Tiejun Tong.
IEEE/ACM Trans Comput Biol Bioinform, 2012 May 02; 9(5). PMID: 22547432    Free PMC article.
Next generation sequencing and a new era of medicine.
Graham Casey, David Conti, Robert Haile, David Duggan.
Gut, 2012 May 03; 62(6). PMID: 22550129    Free PMC article.
Review.
Results of the First Austrian Multidisciplinary Expert Panel on Controversies in Local Treatment of Breast Cancer.
Michael Knauer, Michael Gnant, Florian Fitzal.
Breast Care (Basel), 2012 May 04; 7(1). PMID: 22553475    Free PMC article.
A critical evaluation of network and pathway-based classifiers for outcome prediction in breast cancer.
Christine Staiger, Sidney Cadot, +4 authors, Lodewyk F A Wessels.
PLoS One, 2012 May 05; 7(4). PMID: 22558100    Free PMC article.
Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers.
Matthew W Conklin, Patricia J Keely.
Cell Adh Migr, 2012 May 10; 6(3). PMID: 22568982    Free PMC article.
Review.
Crk adaptor proteins act as key signaling integrators for breast tumorigenesis.
Kelly E Fathers, Emily S Bell, +12 authors, Morag Park.
Breast Cancer Res, 2012 May 10; 14(3). PMID: 22569336    Free PMC article.
A target based approach identifies genomic predictors of breast cancer patient response to chemotherapy.
Robin M Hallett, Gregory Pond, John A Hassell.
BMC Med Genomics, 2012 May 15; 5. PMID: 22578285    Free PMC article.
FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair.
Yun-Yong Park, Sung Yun Jung, +10 authors, Ju-Seog Lee.
Carcinogenesis, 2012 May 15; 33(10). PMID: 22581827    Free PMC article.
Essential gene profiles in breast, pancreatic, and ovarian cancer cells.
Richard Marcotte, Kevin R Brown, +25 authors, Jason Moffat.
Cancer Discov, 2012 May 16; 2(2). PMID: 22585861    Free PMC article.
Highly Cited.
Methazolamide is a new hepatic insulin sensitizer that lowers blood glucose in vivo.
Nicky Konstantopoulos, Juan C Molero, +14 authors, Ken R Walder.
Diabetes, 2012 May 16; 61(8). PMID: 22586591    Free PMC article.
DNA methylation profiling distinguishes three clusters of breast cancer cell lines.
Siyuan Zheng, Zhongming Zhao.
Chem Biodivers, 2012 May 17; 9(5). PMID: 22589087    Free PMC article.
Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer.
Oddbjørn Straume, Takeshi Shimamura, +19 authors, George N Naumov.
Proc Natl Acad Sci U S A, 2012 May 17; 109(22). PMID: 22589302    Free PMC article.
Comparison of data-merging methods with SVM attribute selection and classification in breast cancer gene expression.
Vitoantonio Bevilacqua, Paolo Pannarale, +3 authors, Stefania Tommasi.
BMC Bioinformatics, 2012 May 25; 13 Suppl 7. PMID: 22595006    Free PMC article.
Genome-wide mechanisms of Smad binding.
M Morikawa, D Koinuma, K Miyazono, C-H Heldin.
Oncogene, 2012 May 23; 32(13). PMID: 22614010    Free PMC article.
Review.
Google goes cancer: improving outcome prediction for cancer patients by network-based ranking of marker genes.
Christof Winter, Glen Kristiansen, +18 authors, Robert Grützmann.
PLoS Comput Biol, 2012 May 23; 8(5). PMID: 22615549    Free PMC article.
A methodological approach to unravel organ-specific breast cancer metastasis.
Sébastien Nola, Soraya Sin, +2 authors, Keltouma Driouch.
J Mammary Gland Biol Neoplasia, 2012 May 26; 17(2). PMID: 22628182
Review.
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation.
Mohit Jain, Roland Nilsson, +7 authors, Vamsi K Mootha.
Science, 2012 May 26; 336(6084). PMID: 22628656    Free PMC article.
Highly Cited.
The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis.
Chia-Hsin Chan, Chien-Feng Li, +14 authors, Hui-Kuan Lin.
Cell, 2012 May 29; 149(5). PMID: 22632973    Free PMC article.
Highly Cited.
Tissue banking in a regional hospital: a promising future concept? First report on fresh frozen tissue banking in a hospital without an integrated institute of pathology.
Marco von Strauss und Torney, Ulrich Güller, +3 authors, Markus Zuber.
World J Surg, 2012 May 29; 36(10). PMID: 22638684
The forkhead box transcription factor FOXC1 promotes breast cancer invasion by inducing matrix metalloprotease 7 (MMP7) expression.
Steven T Sizemore, Ruth A Keri.
J Biol Chem, 2012 May 31; 287(29). PMID: 22645147    Free PMC article.
Therapeutic potential for phenytoin: targeting Na(v)1.5 sodium channels to reduce migration and invasion in metastatic breast cancer.
Ming Yang, David J Kozminski, +4 authors, William J Brackenbury.
Breast Cancer Res Treat, 2012 Jun 09; 134(2). PMID: 22678159    Free PMC article.
At the crossroads: EGFR and PTHrP signaling in cancer-mediated diseases of bone.
John Foley, Nicole Nickerson, +3 authors, Anne M Foley.
Odontology, 2012 Jun 12; 100(2). PMID: 22684584    Free PMC article.
Review.
Global secretome analysis identifies novel mediators of bone metastasis.
Mario Andres Blanco, Gary LeRoy, +4 authors, Yibin Kang.
Cell Res, 2012 Jun 13; 22(9). PMID: 22688892    Free PMC article.
Cancer core modules identification through genomic and transcriptomic changes correlation detection at network level.
Wenting Li, Rui Wang, +2 authors, Zhirong Sun.
BMC Syst Biol, 2012 Jun 14; 6. PMID: 22691569    Free PMC article.
Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor β transcription in breast cancer cells.
Lacey M Litchfield, Krista A Riggs, +12 authors, Carolyn M Klinge.
PLoS One, 2012 Jun 14; 7(5). PMID: 22693611    Free PMC article.
Network-induced classification kernels for gene expression profile analysis.
Ofer Lavi, Gideon Dror, Ron Shamir.
J Comput Biol, 2012 Jun 16; 19(6). PMID: 22697242    Free PMC article.
TOP2A RNA expression and recurrence in estrogen receptor-positive breast cancer.
Joseph A Sparano, Lori J Goldstein, +2 authors, Robert Gray.
Breast Cancer Res Treat, 2012 Jun 19; 134(2). PMID: 22706628    Free PMC article.
Expression of the BRCA1 complex member BRE predicts disease free survival in breast cancer.
Sylvie M Noordermeer, Marloes Wennemers, +6 authors, Bert A van der Reijden.
Breast Cancer Res Treat, 2012 Jun 19; 135(1). PMID: 22706632    Free PMC article.
Predicting the response to preoperative radiation or chemoradiation by a microarray analysis of the gene expression profiles in rectal cancer.
Takashi Akiyoshi, Takashi Kobunai, Toshiaki Watanabe.
Surg Today, 2012 Jun 19; 42(8). PMID: 22706722
Review.
A hemocyte gene expression signature correlated with predictive capacity of oysters to survive Vibrio infections.
Rafael Diego Rosa, Julien de Lorgeril, +3 authors, Evelyne Bachère.
BMC Genomics, 2012 Jun 20; 13. PMID: 22708697    Free PMC article.
Overexpression of ribosome binding protein 1 (RRBP1) in breast cancer.
Deepthi Telikicherla, Arivusudar Marimuthu, +5 authors, Akhilesh Pandey.
Clin Proteomics, 2012 Jun 20; 9(1). PMID: 22709790    Free PMC article.
Prognostic signatures in breast cancer: correlation does not imply causation.
Charlotte Ng, Britta Weigelt, Anita Grigoriadis, Jorge S Reis-Filho.
Breast Cancer Res, 2012 Jun 21; 14(3). PMID: 22713235    Free PMC article.
Modulation of DNA repair genes induced by TLR9 agonists: A strategy to eliminate "altered" cells?
Michele Sommariva, Loris De Cecco, Elda Tagliabue, Andrea Balsari.
Oncoimmunology, 2012 Jun 22; 1(2). PMID: 22720263    Free PMC article.
Independent and functional validation of a multi-tumour-type proliferation signature.
M H W Starmans, N G Lieuwes, +8 authors, P Lambin.
Br J Cancer, 2012 Jun 23; 107(3). PMID: 22722312    Free PMC article.
MicroRNA-9 as potential biomarker for breast cancer local recurrence and tumor estrogen receptor status.
Xin Zhou, Catalin Marian, +4 authors, Yun-Ling Zheng.
PLoS One, 2012 Jun 23; 7(6). PMID: 22723919    Free PMC article.
A risk score based on histopathological features predicts higher risk of distant recurrence in premenopausal patients with lymph node-negative endocrine-responsive breast cancer.
Silvia Dellapasqua, Vincenzo Bagnardi, +9 authors, Marco Colleoni.
Breast, 2012 Jul 04; 21(5). PMID: 22749924    Free PMC article.
PAM50 assay and the three-gene model for identifying the major and clinically relevant molecular subtypes of breast cancer.
A Prat, J S Parker, C Fan, C M Perou.
Breast Cancer Res Treat, 2012 Jul 04; 135(1). PMID: 22752290    Free PMC article.
Pathway-based classification of cancer subtypes.
Shinuk Kim, Mark Kon, Charles DeLisi.
Biol Direct, 2012 Jul 05; 7. PMID: 22759382    Free PMC article.
Signatures of tumor-immune interactions as biomarkers for breast cancer prognosis.
Masoud H Manjili, Kayvan Najarian, Xiang-Yang Wang.
Future Oncol, 2012 Jul 07; 8(6). PMID: 22764768    Free PMC article.
Review.
Genome organizing function of SATB1 in tumor progression.
Terumi Kohwi-Shigematsu, Krzysztof Poterlowicz, +3 authors, Yoshinori Kohwi.
Semin Cancer Biol, 2012 Jul 10; 23(2). PMID: 22771615    Free PMC article.
Review.
Identification of Breast Cancer Prognosis Markers via Integrative Analysis.
Shuangge Ma, Ying Dai, Jian Huang, Yang Xie.
Comput Stat Data Anal, 2012 Jul 10; 56(9). PMID: 22773869    Free PMC article.
Loss of expression of the differentially expressed in adenocarcinoma of the lung (DAL-1) protein is associated with metastasis of non-small cell lung carcinoma cells.
Yajie Zhang, Ruobing Xu, +3 authors, Hongyan Wang.
Tumour Biol, 2012 Jul 12; 33(6). PMID: 22782504
Exploring molecular links between lymph node invasion and cancer prognosis in human breast cancer.
Sangwoo Kim, Hojung Nam, Doheon Lee.
BMC Syst Biol, 2012 Jul 20; 5 Suppl 2. PMID: 22784575    Free PMC article.
Integration of breast cancer gene signatures based on graph centrality.
Jianxin Wang, Gang Chen, Min Li, Yi Pan.
BMC Syst Biol, 2012 Jul 20; 5 Suppl 3. PMID: 22784616    Free PMC article.
Kernelized partial least squares for feature reduction and classification of gene microarray data.
Walker H Land, Xingye Qiao, +6 authors, Youping Deng.
BMC Syst Biol, 2012 Jul 20; 5 Suppl 3. PMID: 22784619    Free PMC article.
Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells.
Caining Jin, Hasan Rajabi, +4 authors, Donald Kufe.
PLoS One, 2012 Jul 14; 7(7). PMID: 22792175    Free PMC article.
Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers.
I-Ming Wang, Bin Zhang, +24 authors, Christopher Roberts.
Mol Syst Biol, 2012 Jul 19; 8. PMID: 22806142    Free PMC article.
Overexpression of Cell Cycle Progression Inhibitor Geminin is Associated with Tumor Stem-Like Phenotype of Triple-Negative Breast Cancer.
Maurizio Di Bonito, Monica Cantile, +6 authors, Gerardo Botti.
J Breast Cancer, 2012 Jul 19; 15(2). PMID: 22807933    Free PMC article.
Development of novel breast cancer recurrence prediction model using support vector machine.
Woojae Kim, Ku Sang Kim, +5 authors, Rae Woong Park.
J Breast Cancer, 2012 Jul 19; 15(2). PMID: 22807942    Free PMC article.
The yeast magmas ortholog pam16 has an essential function in fermentative growth that involves sphingolipid metabolism.
Mary K Short, Joshua P Hallett, +5 authors, Paul T Jubinsky.
PLoS One, 2012 Jul 19; 7(7). PMID: 22808036    Free PMC article.
Whole transcriptome RNA-Seq analysis of breast cancer recurrence risk using formalin-fixed paraffin-embedded tumor tissue.
Dominick Sinicropi, Kunbin Qu, +14 authors, Joffre Baker.
PLoS One, 2012 Jul 19; 7(7). PMID: 22808097    Free PMC article.
Integration of clinical and gene expression data has a synergetic effect on predicting breast cancer outcome.
Martin H van Vliet, Hugo M Horlings, +2 authors, Lodewyk F A Wessels.
PLoS One, 2012 Jul 19; 7(7). PMID: 22808140    Free PMC article.
The janus face of lipids in human breast cancer: how polyunsaturated Fatty acids affect tumor cell hallmarks.
Benoît Chénais, Vincent Blanckaert.
Int J Breast Cancer, 2012 Jul 20; 2012. PMID: 22811918    Free PMC article.
Expression and function of the protein tyrosine phosphatase receptor J (PTPRJ) in normal mammary epithelial cells and breast tumors.
Chanel E Smart, Marjan E Askarian Amiri, +17 authors, Stuart Kellie.
PLoS One, 2012 Jul 21; 7(7). PMID: 22815804    Free PMC article.
Identification of a selective small-molecule inhibitor series targeting the eyes absent 2 (Eya2) phosphatase activity.
Aaron B Krueger, Seameen J Dehdashti, +6 authors, Rui Zhao.
J Biomol Screen, 2012 Jul 24; 18(1). PMID: 22820394    Free PMC article.
Activation of Robo1 signaling of breast cancer cells by Slit2 from stromal fibroblast restrains tumorigenesis via blocking PI3K/Akt/β-catenin pathway.
Po-Hao Chang, Wendy W Hwang-Verslues, +7 authors, Wen-Hwa Lee.
Cancer Res, 2012 Jul 25; 72(18). PMID: 22826604    Free PMC article.
Prognostic factors and recurrence in breast cancer: experience at the national cancer institute of Mexico.
A Stankov, J E Bargallo-Rocha, +3 authors, A Meneses-Garcia.
ISRN Oncol, 2012 Jul 26; 2012. PMID: 22830047    Free PMC article.
Validation of a radiosensitivity molecular signature in breast cancer.
Steven A Eschrich, William J Fulp, +9 authors, Javier F Torres-Roca.
Clin Cancer Res, 2012 Jul 27; 18(18). PMID: 22832933    Free PMC article.
The T box transcription factor TBX2 promotes epithelial-mesenchymal transition and invasion of normal and malignant breast epithelial cells.
Bin Wang, Linsey E Lindley, +3 authors, Karoline J Briegel.
PLoS One, 2012 Jul 31; 7(7). PMID: 22844464    Free PMC article.
Age-associated gene expression in normal breast tissue mirrors qualitative age-at-incidence patterns for breast cancer.
Jason R Pirone, Monica D'Arcy, +7 authors, Melissa A Troester.
Cancer Epidemiol Biomarkers Prev, 2012 Aug 04; 21(10). PMID: 22859400    Free PMC article.
An "elite hacker": breast tumors exploit the normal microenvironment program to instruct their progression and biological diversity.
Aaron Boudreau, Laura J van't Veer, Mina J Bissell.
Cell Adh Migr, 2012 Aug 07; 6(3). PMID: 22863741    Free PMC article.
Review.
Transcriptional network analysis identifies BACH1 as a master regulator of breast cancer bone metastasis.
Yajun Liang, Heng Wu, +8 authors, Yibin Kang.
J Biol Chem, 2012 Aug 10; 287(40). PMID: 22875853    Free PMC article.
Understanding how breast cancer patients use risk information from genomic tests.
Jessica T DeFrank, Lisa A Carey, Noel T Brewer.
J Behav Med, 2012 Aug 11; 36(6). PMID: 22878783    Free PMC article.
Mouse p53-deficient cancer models as platforms for obtaining genomic predictors of human cancer clinical outcomes.
Marta Dueñas, Mirentxu Santos, +13 authors, Ramón García-Escudero.
PLoS One, 2012 Aug 11; 7(8). PMID: 22880004    Free PMC article.
Multiwalled carbon nanotube-induced gene signatures in the mouse lung: potential predictive value for human lung cancer risk and prognosis.
Nancy L Guo, Ying-Wooi Wan, +5 authors, Yong Qian.
J Toxicol Environ Health A, 2012 Aug 16; 75(18). PMID: 22891886    Free PMC article.
Biomarkers of cancer metastasis through the lymphovascular system: future perspectives.
Stanley P L Leong, Marlys Witte.
Clin Exp Metastasis, 2012 Aug 16; 29(7). PMID: 22892756
The non-crosslinking fixative RCL2®-CS100 is compatible with both pathology diagnosis and molecular analyses.
Florence Boissière-Michot, Amélie Denouël, +5 authors, Frédéric Bibeau.
Pathol Oncol Res, 2012 Aug 16; 19(1). PMID: 22893391
Scenario drafting to anticipate future developments in technology assessment.
Valesca P Retèl, Manuela A Joore, +2 authors, Wim H van Harten.
BMC Res Notes, 2012 Aug 17; 5. PMID: 22894140    Free PMC article.
The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites.
Hua Gao, Goutam Chakraborty, +7 authors, Filippo G Giancotti.
Cell, 2012 Aug 21; 150(4). PMID: 22901808    Free PMC article.
Highly Cited.
Tamoxifen regulates cell fate through mitochondrial estrogen receptor beta in breast cancer.
M Razandi, A Pedram, +2 authors, E R Levin.
Oncogene, 2012 Aug 22; 32(27). PMID: 22907432    Free PMC article.
Gene profiling in breast cancer.
Inge Peerlink, Kanchan Kaur, Hemant Singhal.
Indian J Surg Oncol, 2010 Jan 01; 1(1). PMID: 22930613    Free PMC article.
A sample selection strategy to boost the statistical power of signature detection in cancer expression profile studies.
Zhenyu Jia, Yipeng Wang, +8 authors, Dan Mercola.
Anticancer Agents Med Chem, 2012 Sep 01; 13(2). PMID: 22934703    Free PMC article.
GPU-FS-kNN: a software tool for fast and scalable kNN computation using GPUs.
Ahmed Shamsul Arefin, Carlos Riveros, Regina Berretta, Pablo Moscato.
PLoS One, 2012 Sep 01; 7(8). PMID: 22937144    Free PMC article.
Integrin-associated CD151 drives ErbB2-evoked mammary tumor onset and metastasis.
Xinyu Deng, Qinglin Li, +14 authors, Xiuwei H Yang.
Neoplasia, 2012 Sep 07; 14(8). PMID: 22952421    Free PMC article.
Weighted frequent gene co-expression network mining to identify genes involved in genome stability.
Jie Zhang, Kewei Lu, +8 authors, Kun Huang.
PLoS Comput Biol, 2012 Sep 08; 8(8). PMID: 22956898    Free PMC article.
Public health in the genomic era: will Public Health Genomics contribute to major changes in the prevention of common diseases?
Evy Cleeren, Johan Van der Heyden, Angela Brand, Herman Van Oyen.
Arch Public Health, 2011 Jan 01; 69(1). PMID: 22958637    Free PMC article.