Review
. 2004 Nov;9(6).
doi: 10.1634/theoncologist.9-6-606.

Prognostic and predictive factors in early-stage breast cancer

Mary Cianfrocca 1 Lori J Goldstein  
Affiliations
  • PMID: 15561805
  •     175 citations

Abstract

Breast cancer is the most common malignancy among American women. Due to increased screening, the majority of patients present with early-stage breast cancer. The Oxford Overview Analysis demonstrates that adjuvant hormonal therapy and polychemotherapy reduce the risk of recurrence and death from breast cancer. Adjuvant systemic therapy, however, has associated risks and it would be useful to be able to optimally select patients most likely to benefit. The purpose of adjuvant systemic therapy is to eradicate distant micrometastatic deposits. It is essential therefore to be able to estimate an individual patient's risk of harboring clinically silent micrometastatic disease using established prognostic factors. It is also beneficial to be able to select the optimal adjuvant therapy for an individual patient based on established predictive factors. It is standard practice to administer systemic therapy to all patients with lymph node-positive disease. However, there are clearly differences among node-positive women that may warrant a more aggressive therapeutic approach. Furthermore, there are many node-negative women who would also benefit from adjuvant systemic therapy. Prognostic factors therefore must be differentiated from predictive factors. A prognostic factor is any measurement available at the time of surgery that correlates with disease-free or overall survival in the absence of systemic adjuvant therapy and, as a result, is able to correlate with the natural history of the disease. In contrast, a predictive factor is any measurement associated with response to a given therapy. Some factors, such as hormone receptors and HER2/neu overexpression, are both prognostic and predictive.

FADD phosphorylation is critical for cell cycle regulation in breast cancer cells.
S Matsuyoshi, K Shimada, +2 authors, N Konishi.
Br J Cancer, 2006 Feb 02; 94(4). PMID: 16450001    Free PMC article.
Expression and possible prognostic role of MAGE-A4, NY-ESO-1, and HER-2 antigens in women with relapsing invasive ductal breast cancer: retrospective immunohistochemical study.
Daniela Bandić, Antonio Juretić, +6 authors, Mirko Samija.
Croat Med J, 2006 Feb 21; 47(1). PMID: 16489695    Free PMC article.
An evaluation of molecular markers for improved detection of breast cancer metastases in sentinel nodes.
S Abdul-Rasool, S H Kidson, +3 authors, G S Hanekom.
J Clin Pathol, 2006 Mar 01; 59(3). PMID: 16505281    Free PMC article.
Analysis of trastuzumab and chemotherapy in advanced breast cancer after the failure of at least one earlier combination: an observational study.
Rupert Bartsch, Catharina Wenzel, +8 authors, Guenther G Steger.
BMC Cancer, 2006 Mar 17; 6. PMID: 16539726    Free PMC article.
The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: correlation with important high-risk prognostic factors.
Hazem Ghebeh, Shamayel Mohammed, +10 authors, Said Dermime.
Neoplasia, 2006 Apr 14; 8(3). PMID: 16611412    Free PMC article.
Highly Cited.
Lymphatic or hematogenous dissemination: how does a metastatic tumor cell decide?
Sunny Y Wong, Richard O Hynes.
Cell Cycle, 2006 Apr 22; 5(8). PMID: 16627996    Free PMC article.
Review.
Comparison of gene expression profiles in core biopsies and corresponding surgical breast cancer samples.
Rosanna Zanetti-Dällenbach, Vincent Vuaroqueaux, +6 authors, Serenella Eppenberger-Castori.
Breast Cancer Res, 2006 Aug 22; 8(4). PMID: 16919157    Free PMC article.
Lymph node status as a guide to selection of available prognostic markers in breast cancer: the clinical practice of the future?
A Elzagheid, T Kuopio, S Pyrhönen, Y Collan.
Diagn Pathol, 2006 Nov 10; 1. PMID: 17092354    Free PMC article.
Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patients.
Lisa K Dunnwald, Mary Anne Rossing, Christopher I Li.
Breast Cancer Res, 2007 Jan 24; 9(1). PMID: 17239243    Free PMC article.
Highly Cited.
The effect of versican G3 domain on local breast cancer invasiveness and bony metastasis.
Albert J M Yee, Margarete Akens, +4 authors, Burton Yang.
Breast Cancer Res, 2007 Jul 31; 9(4). PMID: 17662123    Free PMC article.
Treatment strategies that effectively reduce early recurrence risk in postmenopausal women with endocrine-sensitive breast cancer: AIs upfront vs. switching.
Stefan Paepke, Volker R Jacobs, +5 authors, Marion Kiechle-Bahat.
J Cancer Res Clin Oncol, 2007 Sep 07; 133(12). PMID: 17805570
Review.
The emerging picture of the mouse mammary stem cell.
François Vaillant, Marie-Liesse Asselin-Labat, +2 authors, Jane E Visvader.
Stem Cell Rev, 2007 Sep 18; 3(2). PMID: 17873344
Review.
The role of molecular markers in predicting response to therapy in patients with colorectal cancer.
Veena Shankaran, Kari B Wisinski, Mary F Mulcahy, Al B Benson.
Mol Diagn Ther, 2008 Apr 22; 12(2). PMID: 18422373
Review.
Methodological issues in evaluating cost effectiveness of adjuvant aromatase inhibitors in early breast cancer: a need for improved modelling to aid decision making.
Lieven Annemans.
Pharmacoeconomics, 2008 Apr 24; 26(5). PMID: 18429657
Review.
Triple negative breast cancer compared to hormone receptor negative/HER2 positive breast cancer.
Irfan Cicin, Hakan Karagol, +5 authors, Kazim Uygun.
Med Oncol, 2008 Nov 13; 26(3). PMID: 19003545
Racial disparities in the development of breast cancer metastases among older women: a multilevel study.
Mario Schootman, Donna B Jeffe, William E Gillanders, Rebecca Aft.
Cancer, 2009 Jan 09; 115(4). PMID: 19130463    Free PMC article.
[Prognostic and predictive factors of invasive breast cancer: update 2009].
T Decker, D Hungermann, W Böcker.
Pathologe, 2009 Feb 03; 30(1). PMID: 19184022
14-3-3zeta overexpression defines high risk for breast cancer recurrence and promotes cancer cell survival.
Christopher L Neal, Jun Yao, +10 authors, Dihua Yu.
Cancer Res, 2009 Mar 26; 69(8). PMID: 19318578    Free PMC article.
Mutations in p53, p53 protein overexpression and breast cancer survival.
Pavel Rossner, Marilie D Gammon, +12 authors, Regina M Santella.
J Cell Mol Med, 2009 Jul 16; 13(9B). PMID: 19602056    Free PMC article.
Prediction of outcome of patients with metastatic breast cancer: evaluation with prognostic factors and Nottingham prognostic index.
Mu-Tai Liu, Wen-Tao Huang, +5 authors, Hao-Han Yang.
Support Care Cancer, 2009 Nov 12; 18(12). PMID: 19904562
Fractionated evaluation of immunohistochemical hormone receptor expression enhances prognostic prediction in breast cancer patients treated with tamoxifen as adjuvant therapy.
Ching-hung Lin, Huang-chun Lien, +7 authors, Chiun-sheng Huang.
J Zhejiang Univ Sci B, 2010 Jan 01; 11(1). PMID: 20043345    Free PMC article.
Prognostic value of p53 and bcl-2 expression in patients treated with breast conservative therapy.
Kyubo Kim, Eui Kyu Chie, +7 authors, Sung W Ha.
J Korean Med Sci, 2010 Feb 02; 25(2). PMID: 20119576    Free PMC article.
Diagnosis of second breast cancer events after initial diagnosis of early stage breast cancer.
Diana S M Buist, Linn A Abraham, +7 authors, Breast Cancer Surveillance Consortium.
Breast Cancer Res Treat, 2010 Aug 12; 124(3). PMID: 20700648    Free PMC article.
Merging transcriptomics and metabolomics--advances in breast cancer profiling.
Eldrid Borgan, Beathe Sitter, +6 authors, Ingrid S Gribbestad.
BMC Cancer, 2010 Nov 18; 10. PMID: 21080935    Free PMC article.
Morphologic complexity of epithelial architecture for predicting invasive breast cancer survival.
Mauro Tambasco, Misha Eliasziw, Anthony M Magliocco.
J Transl Med, 2011 Jan 05; 8. PMID: 21194459    Free PMC article.
Health-related quality of life as prognostic factor for response, progression-free survival, and survival in women with metastatic breast cancer.
Helene Svensson, Thomas Hatschek, +2 authors, Yvonne Brandberg.
Med Oncol, 2011 Feb 08; 29(2). PMID: 21298494
Predictive value of pathological and immunohistochemical parameters for axillary lymph node metastasis in breast carcinoma.
Sibel Yenidunya, Reyhan Bayrak, Hacer Haltas.
Diagn Pathol, 2011 Mar 15; 6. PMID: 21396129    Free PMC article.
Combining emerging agents in advanced breast cancer.
Thehang Luu, Cathie Chung, George Somlo.
Oncologist, 2011 May 06; 16(6). PMID: 21543509    Free PMC article.
Review.
Dietary intakes of total and specific lignans are associated with clinical breast tumor characteristics.
Susan E McCann, Katie C Hootman, +7 authors, Swati A Kulkarni.
J Nutr, 2011 Nov 25; 142(1). PMID: 22113872    Free PMC article.
AGO Recommendations for Diagnosis and Treatment of Patients with Primary and Metastatic Breast Cancer. Update 2011.
Christoph Thomssen, Anton Scharl, Nadia Harbeck.
Breast Care (Basel), 2011 Dec 14; 6(4). PMID: 22164127    Free PMC article.
Experimental α-particle radioimmunotherapy of breast cancer using 227Th-labeled p-benzyl-DOTA-trastuzumab.
Nasir Abbas, Helen Heyerdahl, +3 authors, Jostein Dahle.
EJNMMI Res, 2012 Jan 05; 1(1). PMID: 22214432    Free PMC article.
Parametric imaging of the local attenuation coefficient in human axillary lymph nodes assessed using optical coherence tomography.
Loretta Scolaro, Robert A McLaughlin, +5 authors, David D Sampson.
Biomed Opt Express, 2012 Feb 09; 3(2). PMID: 22312589    Free PMC article.
Proteomics of mouse BRCA1-deficient mammary tumors identifies DNA repair proteins with potential diagnostic and prognostic value in human breast cancer.
Marc Warmoes, Janneke E Jaspers, +8 authors, Connie R Jimenez.
Mol Cell Proteomics, 2012 Mar 01; 11(7). PMID: 22366898    Free PMC article.
Individual participant data meta-analysis of prognostic factor studies: state of the art?
Ghada Abo-Zaid, Willi Sauerbrei, Richard D Riley.
BMC Med Res Methodol, 2012 Apr 26; 12. PMID: 22530717    Free PMC article.
Systematic Review.
The role of lymph node metastasis in the systemic dissemination of breast cancer.
S David Nathanson, David Kwon, +2 authors, Dhananjay Chitale.
Indian J Surg Oncol, 2010 Dec 01; 1(4). PMID: 22695980    Free PMC article.
Therapeutic potential of stem cells expressing suicide genes that selectively target human breast cancer cells: evidence that they exert tumoricidal effects via tumor tropism (review).
Bo-Rim Yi, Kelvin J Choi, Seung U Kim, Kyung-Chul Choi.
Int J Oncol, 2012 Jun 28; 41(3). PMID: 22736197    Free PMC article.
Review.
Efficiency of ultrasound and ultrasound-guided fine needle aspiration cytology in preoperative assessment of axillary lymph node metastases in breast cancer.
Aysegul Oz, Figen Basaran Demirkazik, +4 authors, Aysegul Uner.
J Breast Cancer, 2012 Jul 19; 15(2). PMID: 22807939    Free PMC article.
Microcirculatory fraction (MCF(I)) as a potential imaging marker for tumor heterogeneity in breast cancer.
Xiangyu Yang, Ewa Mrozek, +5 authors, Michael V Knopp.
Magn Reson Imaging, 2012 Aug 14; 30(8). PMID: 22884756    Free PMC article.
Prognosis of breast cancer is associated with one-carbon metabolism related nutrients among Korean women.
Yunhee Lee, Sang-Ah Lee, +8 authors, Daehee Kang.
Nutr J, 2012 Aug 30; 11. PMID: 22929014    Free PMC article.
Immunoglobulin kappa C predicts overall survival in node-negative breast cancer.
Zonglin Chen, Aslihan Gerhold-Ay, +13 authors, Marcus Schmidt.
PLoS One, 2012 Oct 03; 7(9). PMID: 23028600    Free PMC article.
Does the axillary lymph node ratio have any added prognostic value over pN staging for South East Asian breast cancer patients?
Nakul Saxena, Mikael Hartman, +7 authors, Helena M Verkooijen.
PLoS One, 2012 Oct 03; 7(9). PMID: 23029254    Free PMC article.
The prognostic and predictive value of mRNA expression of vascular endothelial growth factor family members in breast cancer: a study in primary tumors of high-risk early breast cancer patients participating in a randomized Hellenic Cooperative Oncology Group trial.
Helena Linardou, Konstantine T Kalogeras, +10 authors, George Fountzilas.
Breast Cancer Res, 2012 Nov 14; 14(6). PMID: 23146280    Free PMC article.
Non-invasive proteomics-thinking about personalized breast cancer screening and treatment.
Manuel Debald, Matthias Wolfgarten, +2 authors, Michael Braun.
EPMA J, 2010 Sep 01; 1(3). PMID: 23199085    Free PMC article.
Predictors of early distant metastasis in women with breast cancer.
Erick Sta Rosa Mendoza, Emmanuel Moreno, Priscilla Baetiong Caguioa.
J Cancer Res Clin Oncol, 2013 Jan 04; 139(4). PMID: 23283528
Estrogen receptor, progesterone receptor, and Her 2 Neu positivity and its association with tumour characteristics and menopausal status in a breast cancer cohort from northern Pakistan.
Mohammad Faheem, Humera Mahmood, +2 authors, Javaid Irfan.
Ecancermedicalscience, 2013 Jan 11; 6. PMID: 23304239    Free PMC article.
Prognostic value of single nucleotide polymorphisms of candidate genes associated with inflammation in early stage breast cancer.
James L Murray, Patricia Thompson, +7 authors, Abenaa M Brewster.
Breast Cancer Res Treat, 2013 Mar 27; 138(3). PMID: 23529385    Free PMC article.
Cytoplasmic HuR expression correlates with P-gp, HER-2 positivity, and poor outcome in breast cancer.
Zhongpeng Zhu, Baocheng Wang, +6 authors, Jun Wang.
Tumour Biol, 2013 Apr 23; 34(4). PMID: 23605320
A simple and reproducible prognostic index in luminal ER-positive breast cancers.
I Castellano, L Chiusa, +9 authors, A Sapino.
Ann Oncol, 2013 May 28; 24(9). PMID: 23709174    Free PMC article.
Outcomes of locally advanced breast cancer patients with ≥ 10 positive axillary lymph nodes.
Emre Koca, Taha Y Kuzan, +4 authors, Kadri Altundag.
Med Oncol, 2013 Jun 05; 30(3). PMID: 23729267
Soluble human epidermal growth factor receptor 2 (HER2) levels in patients with HER2-positive breast cancer receiving chemotherapy with or without trastuzumab: results from North Central Cancer Treatment Group adjuvant trial N9831.
Alvaro Moreno-Aspitia, David W Hillman, +11 authors, Edith A Perez.
Cancer, 2013 Jun 08; 119(15). PMID: 23744760    Free PMC article.
A novel intervention using interactive technology and personal narratives to reduce cancer disparities: African American breast cancer survivor stories.
Maria Pérez, Julianne A Sefko, +6 authors, Donna B Jeffe.
J Cancer Surviv, 2013 Sep 14; 8(1). PMID: 24030573    Free PMC article.
High expression of MACC1 predicts poor prognosis in patients with osteosarcoma.
Kai Zhang, Yonggang Zhang, +4 authors, Qing Zhu.
Tumour Biol, 2013 Sep 26; 35(2). PMID: 24065195
The impact of structural uncertainty on cost-effectiveness models for adjuvant endocrine breast cancer treatments: the need for disease-specific model standardization and improved guidance.
Gerardus W J Frederix, Johan G C van Hasselt, +4 authors, Johan L Severens.
Pharmacoeconomics, 2013 Nov 23; 32(1). PMID: 24263964
The relationship between lymphovascular invasion and angiogenesis, hormone receptors, cell proliferation and survival in patients with primary operable invasive ductal breast cancer.
Zahra Ma Mohammed, Donald C McMillan, +4 authors, James J Going.
BMC Clin Pathol, 2013 Nov 28; 13(1). PMID: 24274633    Free PMC article.
S100A14, a member of the EF-hand calcium-binding proteins, is overexpressed in breast cancer and acts as a modulator of HER2 signaling.
Chengshan Xu, Hongyan Chen, +7 authors, Zhihua Liu.
J Biol Chem, 2013 Nov 29; 289(2). PMID: 24285542    Free PMC article.
Semi-automated evaluation of Ki-67 index in invasive ductal carcinoma of the breast.
Cristian Suciu, Anca Muresan, +3 authors, Marius Raica.
Oncol Lett, 2013 Dec 19; 7(1). PMID: 24348830    Free PMC article.
Breast cancer therapy by laser-induced Coulomb explosion of gold nanoparticles.
Muhammad Gul Bahar Ashiq, Mohammad Alam Saeed, +2 authors, Muhammad Nadeem.
Chin J Cancer Res, 2014 Jan 05; 25(6). PMID: 24385705    Free PMC article.
The value of T2* in differentiating metastatic from benign axillary lymph nodes in patients with breast cancer--a preliminary in vivo study.
Chuanming Li, Shan Meng, +2 authors, Jiani Hu.
PLoS One, 2014 Jan 24; 9(1). PMID: 24454715    Free PMC article.
Mechanisms of association between physical functioning and breast cancer mortality: evidence from the Women's Healthy Eating and Living Study.
Catherine Marinac, Ruth E Patterson, +2 authors, John P Pierce.
J Cancer Surviv, 2014 Feb 27; 8(3). PMID: 24570214
Research on drug resistance mechanism of trastuzumab caused by activation of the PI3K/Akt signaling pathway.
Xi Chen, Han Wang, +2 authors, Jing-Jing Wu.
Contemp Oncol (Pozn), 2013 Jan 01; 17(4). PMID: 24592124    Free PMC article.
Clinical utility of aromatase inhibitors as adjuvant treatment in postmenopausal early breast cancer.
Arturo Loaiza-Bonilla, Francisco Socola, Stefan Glück.
Clin Med Insights Womens Health, 2013 Jan 01; 6. PMID: 24665209    Free PMC article.
Review.
A pilot study comparing the effect of flaxseed, aromatase inhibitor, and the combination on breast tumor biomarkers.
Susan E McCann, Stephen B Edge, +7 authors, Swati Kulkarni.
Nutr Cancer, 2014 Mar 29; 66(4). PMID: 24669750    Free PMC article.
G protein-coupled estrogen receptor regulates mammary tumorigenesis and metastasis.
Nicole A Marjon, Chelin Hu, Helen J Hathaway, Eric R Prossnitz.
Mol Cancer Res, 2014 Jul 18; 12(11). PMID: 25030371    Free PMC article.
Calponin-h2: a potential serum marker for the early detection of human breast cancer?
Manuel Debald, Jian-Ping Jin, +7 authors, Gisela Walgenbach-Brünagel.
Tumour Biol, 2014 Aug 08; 35(11). PMID: 25099617
Membranous Nectin-4 expression is a risk factor for distant relapse of T1-T2, N0 luminal-A early breast cancer.
R Lattanzio, R Ghasemi, +7 authors, M Piantelli.
Oncogenesis, 2014 Sep 02; 3. PMID: 25178039    Free PMC article.
Elevated CXCL1 expression in breast cancer stroma predicts poor prognosis and is inversely associated with expression of TGF-β signaling proteins.
An Zou, Diana Lambert, +4 authors, Nikki Cheng.
BMC Cancer, 2014 Oct 26; 14. PMID: 25344051    Free PMC article.
Impact of preoperative anemia on relapse and survival in breast cancer patients.
YingJun Zhang, YuYang Chen, +7 authors, Weian Zeng.
BMC Cancer, 2014 Nov 20; 14. PMID: 25406979    Free PMC article.
Prognostic factors of second primary contralateral breast cancer in early-stage breast cancer.
Zheng Li, Fabrice Sergent, +2 authors, Isabelle Gabelle-Flandin.
Oncol Lett, 2014 Dec 02; 9(1). PMID: 25435968    Free PMC article.
Phase II, multicenter, open-label, randomized study of YM155 plus docetaxel as first-line treatment in patients with HER2-negative metastatic breast cancer.
Michael R Clemens, Oleg A Gladkov, +5 authors, Anne Keating.
Breast Cancer Res Treat, 2014 Dec 31; 149(1). PMID: 25547219    Free PMC article.
Intrinsic cancer subtypes--next steps into personalized medicine.
Cristina Santos, Rebeca Sanz-Pamplona, +6 authors, Ramon Salazar.
Cell Oncol (Dordr), 2015 Jan 15; 38(1). PMID: 25586691
Review.
Angiogenesis in Breast Cancer and its Correlation with Estrogen, Progesterone Receptors and other Prognostic Factors.
Jyotsna Naresh Bharti, Poonam Rani, Vinay Kamal, Prem Narayan Agarwal.
J Clin Diagn Res, 2015 Mar 05; 9(1). PMID: 25737993    Free PMC article.
Prediction of breast cancer survival using clinical and genetic markers by tumor subtypes.
Nan Song, Ji-Yeob Choi, +12 authors, Daehee Kang.
PLoS One, 2015 Apr 14; 10(4). PMID: 25867717    Free PMC article.
Development and validation of a novel platform-independent metastasis signature in human breast cancer.
Shuang G Zhao, Mark Shilkrut, +5 authors, Felix Y Feng.
PLoS One, 2015 May 15; 10(5). PMID: 25974184    Free PMC article.
Low expression levels of hepsin and TMPRSS3 are associated with poor breast cancer survival.
Mikko Pelkonen, Kaisa Luostari, +6 authors, Arto Mannermaa.
BMC Cancer, 2015 May 28; 15. PMID: 26014348    Free PMC article.
Cripto-1 as a novel therapeutic target for triple negative breast cancer.
Nadia P Castro, Natalie D Fedorova-Abrams, +8 authors, David S Salomon.
Oncotarget, 2015 Jun 11; 6(14). PMID: 26059540    Free PMC article.
The impact of preoperative axillary ultrasonography in T1 breast tumours.
Javier del Riego, María Jesús Diaz-Ruiz, +5 authors, Grup de Mama Vallès-Osona-Bages (GMVOB; Cooperative Breast Workgroup Vallés-Osona-Bagés).
Eur Radiol, 2015 Jul 15; 26(4). PMID: 26162580
Digital imaging in the immunohistochemical evaluation of the proliferation markers Ki67, MCM2 and Geminin, in early breast cancer, and their putative prognostic value.
Shalaka Joshi, Johnathan Watkins, +4 authors, Sarah E Pinder.
BMC Cancer, 2015 Jul 25; 15. PMID: 26205655    Free PMC article.
First-in-Class CDK4/6 Inhibitor Palbociclib Could Usher in a New Wave of Combination Therapies for HR+, HER2- Breast Cancer.
Jack McCain.
P T, 2015 Aug 04; 40(8). PMID: 26236140    Free PMC article.
DNA repair prognostic index modelling reveals an essential role for base excision repair in influencing clinical outcomes in ER negative and triple negative breast cancers.
Tarek M A Abdel-Fatah, Arvind Arora, +6 authors, Srinivasan Madhusudan.
Oncotarget, 2015 Aug 13; 6(26). PMID: 26267318    Free PMC article.
Cancer research: from prognostic genes to therapeutic targets.
Rosemarie Marchan.
EXCLI J, 2014 Jan 01; 13. PMID: 26417341    Free PMC article.
Comprehensive profiling of biological processes reveals two major prognostic subtypes in breast cancer.
Fei Chen, Sheng Gao, +7 authors, Hong Yin.
Tumour Biol, 2015 Oct 09; 37(3). PMID: 26446459
DNA methylation assessment as a prognostic factor in invasive breast cancer using methylation-specific multiplex ligation dependent probe amplification.
Halaleh Shakeri, Jalal Gharesouran, +2 authors, Seyyed Mojtaba Mohaddes Ardebili.
EXCLI J, 2016 Apr 12; 15. PMID: 27065772    Free PMC article.
Optimal Ki67 cut-off for luminal breast cancer prognostic evaluation: a large case series study with a long-term follow-up.
Sara Bustreo, Simona Osella-Abate, +6 authors, Isabella Castellano.
Breast Cancer Res Treat, 2016 May 09; 157(2). PMID: 27155668    Free PMC article.
How do women trade-off benefits and risks in chemotherapy treatment decisions based on gene expression profiling for early-stage breast cancer? A discrete choice experiment.
Deborah A Marshall, Ken Deal, +3 authors, Maureen Trudeau.
BMJ Open, 2016 Jun 04; 6(6). PMID: 27256091    Free PMC article.
Clinical Implications of the Progression-Free Survival Endpoint for Treatment of Hormone Receptor-Positive Advanced Breast Cancer.
Virginia G Kaklamani.
Oncologist, 2016 Jun 04; 21(8). PMID: 27256875    Free PMC article.
Review.
Diagnostic accuracy of metastatic axillary lymph nodes in breast MRI.
Gozde Arslan, Kubra Murzoglu Altintoprak, +2 authors, Levent Celik.
Springerplus, 2016 Jul 05; 5(1). PMID: 27376003    Free PMC article.
High expression of TRPM8 predicts poor prognosis in patients with osteosarcoma.
Wei Zhao, Huimian Xu.
Oncol Lett, 2016 Jul 23; 12(2). PMID: 27446440    Free PMC article.
Effect of Lump Size and Nodal Status on Prognosis in Invasive Breast Cancer: Experience from Rural India.
Monique Garg, Nitin Nagpal, Darshan Singh Sidhu, Amandeep Singh.
J Clin Diagn Res, 2016 Aug 10; 10(6). PMID: 27504343    Free PMC article.
Adjuvant Trastuzumab in HER2-Positive Early Breast Cancer by Age and Hormone Receptor Status: A Cost-Utility Analysis.
William Leung, Giorgi Kvizhinadze, Nisha Nair, Tony Blakely.
PLoS Med, 2016 Aug 10; 13(8). PMID: 27504960    Free PMC article.
Potential Indexing of the Invasiveness of Breast Cancer Cells by Mitochondrial Redox Ratios.
Nannan Sun, He N Xu, Qingming Luo, Lin Z Li.
Adv Exp Med Biol, 2016 Aug 16; 923. PMID: 27526133    Free PMC article.
Prognostic value of HER2 status in bladder transitional cell carcinoma revealed by both IHC and BDISH techniques.
Taoufik Nedjadi, Jaudah Al-Maghrabi, +8 authors, Mohammed Al-Qahtani.
BMC Cancer, 2016 Aug 20; 16. PMID: 27539085    Free PMC article.
Comparison of clinicopathological characteristics of lymph node positive and lymph node negative breast cancer.
Naila Irum Hadi, Qamar Jamal.
Pak J Med Sci, 2016 Sep 21; 32(4). PMID: 27648029    Free PMC article.
The Association between Treatment for Metabolic Disorders and Breast Cancer Characteristics.
Hadar Goldvaser, Shulamith Rizel, +6 authors, Rinat Yerushalmi.
Int J Endocrinol, 2016 Sep 21; 2016. PMID: 27648070    Free PMC article.
Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer.
Gabriele Corda, Gianluca Sala, +22 authors, Arturo Sala.
J Pathol, 2016 Nov 20; 241(3). PMID: 27859262    Free PMC article.
Role of Axillary Ultrasound, Fine Needle Aspiration Cytology and Sentinel Lymph Node Biopsy in clinically N0 Breast Cancer.
Gaurav Goel, P D Janaki, +4 authors, D K Vijaykumar.
Indian J Surg Oncol, 2016 Nov 23; 7(4). PMID: 27872527    Free PMC article.
Recent perspectives of breast cancer prognosis and predictive factors.
Su-Sheng Cao, Cun-Tao Lu.
Oncol Lett, 2016 Dec 03; 12(5). PMID: 27900052    Free PMC article.
A Hybrid Computer-aided-diagnosis System for Prediction of Breast Cancer Recurrence (HPBCR) Using Optimized Ensemble Learning.
Mohammad R Mohebian, Hamid R Marateb, +2 authors, Fariborz Mokarian.
Comput Struct Biotechnol J, 2016 Dec 27; 15. PMID: 28018557    Free PMC article.
Distinctions in Breast Tumor Recurrence Patterns Post-Therapy among Racially Distinct Populations.
Nikita Wright, Jun Xia, +11 authors, Ritu Aneja.
PLoS One, 2017 Jan 14; 12(1). PMID: 28085947    Free PMC article.
A circulating tumor cell cluster-based model for tumor metastasis (Hypothesis).
Yupeng Hong, Ziduo Li, Qi Zhang.
Oncol Lett, 2017 Jan 21; 12(6). PMID: 28105198    Free PMC article.
Genome-wide screen identifies a novel prognostic signature for breast cancer survival.
Xuan Y Mao, Matthew J Lee, +3 authors, Antoine M Snijders.
Oncotarget, 2017 Jan 26; 8(8). PMID: 28122328    Free PMC article.
Prediction of years of life after diagnosis of breast cancer using omics and omic-by-treatment interactions.
Agustín González-Reymúndez, Gustavo de Los Campos, +2 authors, Ana I Vazquez.
Eur J Hum Genet, 2017 Mar 09; 25(5). PMID: 28272536    Free PMC article.
Cellular organization and molecular differentiation model of breast cancer-associated fibroblasts.
Susann Busch, Daniel Andersson, +3 authors, Göran Landberg.
Mol Cancer, 2017 Apr 05; 16(1). PMID: 28372546    Free PMC article.
Patients with uterine leiomyoma exhibit a high incidence but low mortality rate for breast cancer.
Te-Chun Shen, Te-Chun Hsia, +7 authors, Da-Tian Bau.
Oncotarget, 2017 Apr 06; 8(20). PMID: 28380432    Free PMC article.
Histamine therapeutic efficacy in metastatic melanoma: Role of histamine H4 receptor agonists and opportunity for combination with radiation.
Noelia A Massari, Melisa B Nicoud, +6 authors, Vanina A Medina.
Oncotarget, 2017 May 04; 8(16). PMID: 28460440    Free PMC article.
Serum sonic hedgehog (SHH) and interleukin-(IL-6) as dual prognostic biomarkers in progressive metastatic breast cancer.
A S Noman, M Uddin, +30 authors, S S Islam.
Sci Rep, 2017 May 13; 7(1). PMID: 28496132    Free PMC article.
The prediction models for postoperative overall survival and disease-free survival in patients with breast cancer.
Daichi Shigemizu, Takuji Iwase, +6 authors, Tatsuhiko Tsunoda.
Cancer Med, 2017 May 26; 6(7). PMID: 28544536    Free PMC article.
Magee Equation 3 predicts pathologic response to neoadjuvant systemic chemotherapy in estrogen receptor positive, HER2 negative/equivocal breast tumors.
Daniel J Farrugia, Alessandra Landmann, +13 authors, Rohit Bhargava.
Mod Pathol, 2017 May 27; 30(8). PMID: 28548119
Interaction of mammographic breast density with menopausal status and postmenopausal hormone use in relation to the risk of aggressive breast cancer subtypes.
Lusine Yaghjyan, Rulla M Tamimi, +15 authors, Celine M Vachon.
Breast Cancer Res Treat, 2017 Jun 19; 165(2). PMID: 28624977    Free PMC article.
Molecular genetics complexity impeding research progress in breast and ovarian cancers.
Ishita Gupta, Ikram Burney, Mansour S Al-Moundhri, Yahya Tamimi.
Mol Clin Oncol, 2017 Jul 08; 7(1). PMID: 28685067    Free PMC article.
Nomograms for preoperative prediction of axillary nodal status in breast cancer.
L Dihge, P-O Bendahl, L Rydén.
Br J Surg, 2017 Jul 19; 104(11). PMID: 28718896    Free PMC article.
Percentage change of primary tumor on 18F-FDG PET/CT as a prognostic factor for invasive ductal breast cancer with axillary lymph node metastasis: Comparison with MRI.
Jang Yoo, Bom Sahn Kim, Jin Chung, Hai-Jeon Yoon.
Medicine (Baltimore), 2017 Aug 03; 96(31). PMID: 28767583    Free PMC article.
Lymph node status have a prognostic impact in breast cancer patients with distant metastasis.
Chuangang Tang, Pei Wang, +4 authors, Changwen Li.
PLoS One, 2017 Aug 15; 12(8). PMID: 28806399    Free PMC article.
Increased risk of recurrence associated with certain risk factors in breast cancer patients after DIEP-flap reconstruction and lipofilling-a matched cohort study with 200 patients.
Sonia Fertsch, Mazen Hagouan, +7 authors, Oliver Christian Thamm.
Gland Surg, 2017 Sep 02; 6(4). PMID: 28861370    Free PMC article.
Relationship Between PD-L1 Expression and Clinical Characteristics in Patients with Breast Invasive Ductal Carcinoma.
Jian Lou, Yuefen Zhou, Jianhui Huang, Xiaojun Qian.
Open Med (Wars), 2017 Sep 13; 12. PMID: 28894845    Free PMC article.
Multi-center study on patient selection for and the oncologic safety of intraoperative radiotherapy (IORT) with the Xoft Axxent® eBx® System for the management of early stage breast cancer in Taiwan.
Hung-Wen Lai, Liang-Chih Liu, +14 authors, Fang-Ming Chen.
PLoS One, 2017 Nov 03; 12(11). PMID: 29095832    Free PMC article.
Triptorelin: A Review of its Use as an Adjuvant Anticancer Therapy in Early Breast Cancer.
James E Frampton.
Drugs, 2017 Nov 28; 77(18). PMID: 29177573
Review.
Decreased expression of CADM1 and CADM4 are associated with advanced stage breast cancer.
Motonobu Saito, Akiteru Goto, +5 authors, Seiichi Takenoshita.
Oncol Lett, 2018 Feb 13; 15(2). PMID: 29434950    Free PMC article.
A hierarchical prognostic model for risk stratification in patients with early breast cancer according to 18 F-fludeoxyglucose uptake and clinicopathological parameters.
Jongtae Cha, Hyung Seok Park, +4 authors, Mijin Yun.
Cancer Med, 2018 Feb 27; 7(4). PMID: 29479851    Free PMC article.
Genomic and clinical predictors for improving estimator precision in randomized trials of breast cancer treatments.
Prasad Patil, Elizabeth Colantuoni, Jeffrey T Leek, Michael Rosenblum.
Contemp Clin Trials Commun, 2016 Mar 31; 3. PMID: 29736456    Free PMC article.
Axillary ultrasound and fine needle aspiration biopsy in the preoperative diagnosis of axillary metastases in early-stage breast cancer.
Xin Hu, Xiao Zhou, +3 authors, Jianlun Liu.
Oncol Lett, 2018 May 29; 15(6). PMID: 29805585    Free PMC article.
The association between Notch4 expression, and clinicopathological characteristics and clinical outcomes in patients with breast cancer.
Jing-Wei Wang, Xiao-Long Wei, +3 authors, Guo-Jun Zhang.
Oncol Lett, 2018 May 29; 15(6). PMID: 29805613    Free PMC article.
CXCR4/CXCL12 Signaling and Protumor Macrophages in Primary Tumors and Sentinel Lymph Nodes Are Involved in Luminal B Breast Cancer Progression.
Carlotta Raschioni, Giulia Bottai, +8 authors, Luca Di Tommaso.
Dis Markers, 2018 Jun 01; 2018. PMID: 29849822    Free PMC article.
Treatment patterns for adjuvant docetaxel-based chemotherapy in early-stage breast cancer in China: A pooled retrospective analysis of four observational studies.
Binghe Xu, Zhimin Shao, +7 authors, Shu Wang.
Chin J Cancer Res, 2018 Jul 27; 30(3). PMID: 30046227    Free PMC article.
Associations of angiogenesis-related proteins with specific prognostic factors, breast cancer subtypes and survival outcome in early-stage breast cancer patients. A Hellenic Cooperative Oncology Group (HeCOG) trial.
Anna Goussia, Nafsika Simou, +24 authors, Anna Batistatou.
PLoS One, 2018 Aug 01; 13(7). PMID: 30063723    Free PMC article.
Associations between obesity, smoking and lymph node status at breast cancer diagnosis in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial.
Amelia Smith, Maeve Mullooly, +2 authors, Kathleen Bennett.
PLoS One, 2018 Aug 30; 13(8). PMID: 30157224    Free PMC article.
Is postmastectomy radiotherapy really needed in breast cancer patients with many positive axillary lymph nodes?
Tanja Marinko, Karmen Stanic.
Radiol Oncol, 2018 Sep 14; 52(3). PMID: 30210045    Free PMC article.
Oncological safety of autologous breast reconstruction after mastectomy for invasive breast cancer.
Joachim Geers, Hans Wildiers, +6 authors, Ann Smeets.
BMC Cancer, 2018 Oct 21; 18(1). PMID: 30340548    Free PMC article.
Predicting the response to neoadjuvant therapy for early-stage breast cancer: tumor-, blood-, and imaging-related biomarkers.
Wenyong Tan, Ming Yang, +2 authors, Weixi Shen.
Cancer Manag Res, 2018 Oct 24; 10. PMID: 30349367    Free PMC article.
Review.
Dosimetric evaluation and systematic review of radiation therapy techniques for early stage node-negative breast cancer treatment.
Tabitha Y Chan, Johann I Tang, Poh Wee Tan, Neill Roberts.
Cancer Manag Res, 2018 Nov 15; 10. PMID: 30425577    Free PMC article.
Review.
Machine Learning With K-Means Dimensional Reduction for Predicting Survival Outcomes in Patients With Breast Cancer.
Melissa Zhao, Yushi Tang, Hyunkyung Kim, Kohei Hasegawa.
Cancer Inform, 2018 Nov 21; 17. PMID: 30455569    Free PMC article.
CDK4/6 inhibition in low burden and extensive metastatic breast cancer: summary of an ESMO Open-Cancer Horizons pro and con discussion.
Ahmad Awada, Joseph Gligorov, +3 authors, Christoph Zielinski.
ESMO Open, 2019 Dec 05; 4(6). PMID: 31798979    Free PMC article.
Review.
Review of methods and applications of attenuation coefficient measurements with optical coherence tomography.
Shuang Chang, Audrey K Bowden.
J Biomed Opt, 2019 Sep 15; 24(9). PMID: 31520468    Free PMC article.
Review.
SLX4IP and telomere dynamics dictate breast cancer metastasis and therapeutic responsiveness.
Nathaniel J Robinson, Chevaun D Morrison-Smith, +4 authors, William P Schiemann.
Life Sci Alliance, 2020 Feb 20; 3(4). PMID: 32071280    Free PMC article.
MAGI1, a New Potential Tumor Suppressor Gene in Estrogen Receptor Positive Breast Cancer.
Begoña Alday-Parejo, François Richard, +5 authors, Curzio Rüegg.
Cancers (Basel), 2020 Jan 23; 12(1). PMID: 31963297    Free PMC article.
Association of white blood cell count with breast cancer burden varies according to menopausal status, body mass index, and hormone receptor status: a case-control study.
Byoungjin Park, Hye Sun Lee, Ji Won Lee, Seho Park.
Sci Rep, 2019 Apr 10; 9(1). PMID: 30962496    Free PMC article.
Prognostic Significance of Metabolic Parameters and Textural Features on 18F-FDG PET/CT in Invasive Ductal Carcinoma of Breast.
Chin-Chuan Chang, Chao-Jung Chen, +3 authors, Yu-Chang Tyan.
Sci Rep, 2019 Jul 31; 9(1). PMID: 31358786    Free PMC article.
Metabolic Pathway Analysis and Effectiveness of Tamoxifen in Danish Breast Cancer Patients.
Thomas P Ahern, Lindsay J Collin, +16 authors, Deirdre Cronin-Fenton.
Cancer Epidemiol Biomarkers Prev, 2020 Jan 15; 29(3). PMID: 31932415    Free PMC article.
p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value.
Angela Santoro, Thalia Vlachou, +16 authors, Pier Giuseppe Pelicci.
Cell Rep, 2019 Jan 17; 26(3). PMID: 30650356    Free PMC article.
Clinical validation of an immunohistochemistry-based CanAssist-Breast test for distant recurrence prediction in hormone receptor-positive breast cancer patients.
Manjiri M Bakre, Charusheila Ramkumar, +10 authors, Mark D Pegram.
Cancer Med, 2019 Mar 09; 8(4). PMID: 30848103    Free PMC article.
Trastuzumab plus adjuvant chemotherapy for human epidermal growth factor receptor 2 (HER2)-positive early-stage breast cancer: A real-world retrospective study in Chinese patients.
Jihong Guo, Qing Li, +8 authors, Binghe Xu.
Chin J Cancer Res, 2019 Dec 10; 31(5). PMID: 31814680    Free PMC article.
Evaluation of long-chain acyl-coenzyme A synthetase 4 (ACSL4) expression in human breast cancer.
Negar Dinarvand, Hossein Khanahmad, +3 authors, Morteza Pourfarzam.
Res Pharm Sci, 2020 Mar 18; 15(1). PMID: 32180816    Free PMC article.
Impact of Obesity on Clinicopathologic Characteristics and Disease Prognosis in Pre- and Postmenopausal Breast Cancer Patients: A Retrospective Institutional Study.
Nehad M Ayoub, Rami J Yaghan, +3 authors, Alia H Al-Mohtaseb.
J Obes, 2019 Apr 26; 2019. PMID: 31019808    Free PMC article.
Long-term survival outcomes in invasive lobular carcinoma patients with and without preoperative MR imaging: a matched cohort study.
Su Min Ha, Eun Young Chae, +3 authors, Woo Jung Choi.
Eur Radiol, 2019 Jan 09; 29(5). PMID: 30617471
Stem cells, immortality, and the evolution of metastatic properties in breast cancer: telomere maintenance mechanisms and metastatic evolution.
Nathaniel J Robinson, Derek J Taylor, William P Schiemann.
J Cancer Metastasis Treat, 2019 Aug 24; 5. PMID: 31440584    Free PMC article.
A multi-institutional real world data study from India of 3453 non-metastatic breast cancer patients undergoing upfront surgery.
Dinesh Chandra Doval, Selvi Radhakrishna, +11 authors, Ramesh B V Nimmagadda.
Sci Rep, 2020 Apr 05; 10(1). PMID: 32246015    Free PMC article.
Clinical association of progesterone receptor isoform A with breast cancer metastasis consistent with its unique mechanistic role in preclinical models.
Rayna Rosati, Kailey Oppat, +2 authors, Manohar Ratnam.
BMC Cancer, 2020 Jun 05; 20(1). PMID: 32493230    Free PMC article.
Candidate methylation sites associated with endocrine therapy resistance in ER+/HER2- breast cancer.
Maryam Soleimani Dodaran, Simone Borgoni, +4 authors, Antoine H C van Kampen.
BMC Cancer, 2020 Jul 21; 20(1). PMID: 32684154    Free PMC article.
CHARACTERISTICS AND PROGNOSIS OF TRIPLE-NEGATIVE BREAST CANCER PATIENTS: A CROATIAN SINGLE INstitution RETROSPECTIVE COHORT STUDY.
Ana Tečić Vuger, Robert Šeparović, +6 authors, Damir Vrbanec.
Acta Clin Croat, 2020 Jul 30; 59(1). PMID: 32724280    Free PMC article.
Meta-Analysis of Prevalence of Triple-Negative Breast Cancer and Its Clinical Features at Incidence in Indian Patients With Breast Cancer.
Apurv Kulkarni, Devaki A Kelkar, +3 authors, Madhura Kulkarni.
JCO Glob Oncol, 2020 Jul 09; 6. PMID: 32639876    Free PMC article.
BCL-2 expression aids in the immunohistochemical prediction of the Oncotype DX breast cancer recurrence score.
Mark D Zarella, Rebecca C Heintzelman, Nikolay K Popnikolov, Fernando U Garcia.
BMC Clin Pathol, 2018 Dec 24; 18. PMID: 30574014    Free PMC article.
Molecular subtypes are prognostic for N3 breast cancer patients in the modern therapeutic era.
Özlem Yersal, Muhammed Ali Kaplan, +5 authors, Nezih Meydan.
Mol Clin Oncol, 2019 Jan 19; 10(1). PMID: 30655995    Free PMC article.
Assessment of Ki-67 as a potential biomarker in patients with breast cancer.
Halla Mohamed Ragab, Nervana Samy, +2 authors, HebatAllah Mohamed Shaaban.
J Genet Eng Biotechnol, 2019 Feb 09; 16(2). PMID: 30733763    Free PMC article.
Association between Ki-67 expression and clinicopathological features in prognosis of breast cancer: A retrospective cohort study.
Hosein Kamranzadeh, Reza Manouchehri Ardekani, +4 authors, Nasrollah Maleki.
J Res Med Sci, 2019 May 31; 24. PMID: 31143231    Free PMC article.
Long-Term Use of Tamoxifen Is Associated With a Decreased Subsequent Meningioma Risk in Patients With Breast Cancer: A Nationwide Population-Based Cohort Study.
Li-Min Sun, Cheng-Li Lin, +3 authors, Chia-Hung Kao.
Front Pharmacol, 2019 Jun 30; 10. PMID: 31249531    Free PMC article.
Predictive factors affecting axillary lymph node involvement in patients with breast cancer in Duhok: Cross-sectional study.
Ayad Ahmad Mohammed.
Ann Med Surg (Lond), 2019 Jul 26; 44. PMID: 31341618    Free PMC article.
Comparison of GenesWell BCT Score With Oncotype DX Recurrence Score for Risk Classification in Asian Women With Hormone Receptor-Positive, HER2-Negative Early Breast Cancer.
Mi Jeong Kwon, Jeong Eon Lee, +12 authors, Young Kee Shin.
Front Oncol, 2019 Aug 14; 9. PMID: 31404265    Free PMC article.
Patient Characteristics and Outcomes of Nonmetastatic Breast Cancer in Haiti: Results from a Retrospective Cohort.
Temidayo Fadelu, Ruth Damuse, +5 authors, Lawrence N Shulman.
Oncologist, 2020 Jun 26; 25(9). PMID: 32584461    Free PMC article.
Prognostic biomarkers related to breast cancer recurrence identified based on Logit model analysis.
Xiaoying Zhou, Chuanguang Xiao, +6 authors, Lili Lin.
World J Surg Oncol, 2020 Sep 27; 18(1). PMID: 32977823    Free PMC article.
A Nomogram Combined Radiomics and Kinetic Curve Pattern as Imaging Biomarker for Detecting Metastatic Axillary Lymph Node in Invasive Breast Cancer.
Yan-Na Shan, Wen Xu, +3 authors, Qi-Jun Shen.
Front Oncol, 2020 Sep 29; 10. PMID: 32983979    Free PMC article.
Genome-wide analysis of therapeutic response uncovers molecular pathways governing tamoxifen resistance in ER+ breast cancer.
Sarra M Rahem, Nusrat J Epsi, Frederick D Coffman, Antonina Mitrofanova.
EBioMedicine, 2020 Oct 26; 61. PMID: 33099086    Free PMC article.
Predicting Axillary Lymph Node Status With a Nomogram Based on Breast Lesion Ultrasound Features: Performance in N1 Breast Cancer Patients.
Yanwen Luo, Chenyang Zhao, +7 authors, Qingli Zhu.
Front Oncol, 2020 Nov 17; 10. PMID: 33194714    Free PMC article.
Influence of built environment on quality of life changes in African-American patients with non-metastatic breast cancer.
M Schootman, M Perez, +6 authors, D B Jeffe.
Health Place, 2020 Jun 17; 63. PMID: 32543424    Free PMC article.
Perfusion contrast-enhanced ultrasound to predict early lymph-node metastasis in breast cancer.
Naoko Mori, Shunji Mugikura, +6 authors, Kei Takase.
Jpn J Radiol, 2018 Nov 22; 37(2). PMID: 30460444
Prognostic models for breast cancer: a systematic review.
Minh Tung Phung, Sandar Tin Tin, J Mark Elwood.
BMC Cancer, 2019 Mar 16; 19(1). PMID: 30871490    Free PMC article.
Systematic Review.
Prognostic role of Tif1γ expression and circulating tumor cells in patients with breast cancer.
Fengfeng Cai, Lu Cai, +6 authors, Ewelina Biskup.
Mol Med Rep, 2019 Mar 22; 19(5). PMID: 30896800    Free PMC article.
Locally advanced breast cancer treated with neoadjuvant chemotherapy and adjuvant radiotherapy: a retrospective cohort analysis.
Jonathan Klein, William Tran, +6 authors, Gregory J Czarnota.
BMC Cancer, 2019 Apr 05; 19(1). PMID: 30943923    Free PMC article.
Pharmacogenomics, CYP2D6, and Tamoxifen: A Survey of the Reasons Sustaining European Clinical Practice Paradigms.
Sara S Reis, Ana S Carvalho, Rúben Fernandes.
Medicina (Kaunas), 2019 Jul 10; 55(7). PMID: 31284530    Free PMC article.
A multiple breast cancer stem cell model to predict recurrence of T1-3, N0 breast cancer.
Yan Qiu, Liya Wang, +8 authors, Hong Bu.
BMC Cancer, 2019 Jul 26; 19(1). PMID: 31340763    Free PMC article.
PLC-gamma-1 phosphorylation status is prognostic of metastatic risk in patients with early-stage Luminal-A and -B breast cancer subtypes.
Rossano Lattanzio, Manuela Iezzi, +8 authors, Mauro Piantelli.
BMC Cancer, 2019 Aug 01; 19(1). PMID: 31362705    Free PMC article.
To Evaluate the Accuracy of Axillary Staging Using Ultrasound and Ultrasound-Guided Fine-Needle Aspiration Cytology (USG-FNAC) in Early Breast Cancer Patients-a Prospective Study.
Rashpal Singh, S V S Deo, +2 authors, Sanjay Thulkar.
Indian J Surg Oncol, 2020 Dec 08; 11(4). PMID: 33281412    Free PMC article.
Radiomics Nomogram of DCE-MRI for the Prediction of Axillary Lymph Node Metastasis in Breast Cancer.
Ning Mao, Yi Dai, +5 authors, Nan Hong.
Front Oncol, 2021 Jan 01; 10. PMID: 33381444    Free PMC article.
Evaluation of glucocorticoid-induced TNF receptor (GITR) expression in breast cancer and across multiple tumor types.
Mayanne M T Zhu, Samantha Burugu, +5 authors, Torsten O Nielsen.
Mod Pathol, 2020 May 01; 33(9). PMID: 32350416
Targeting the purinergic pathway in breast cancer and its therapeutic applications.
Julia Beatrice de Araújo, Vanessa Vitória Kerkhoff, Sarah Franco Vieira de Oliveira Maciel, Débora Tavares de Resende E Silva.
Purinergic Signal, 2021 Feb 13;. PMID: 33576905    Free PMC article.
Review.
Prognostic value of p53 expression in hormone receptor-positive and human epidermal growth factor receptor 2-negative breast cancer patients receiving neoadjuvant chemotherapy.
Loai Saleh Albinsaad, Jisun Kim, +6 authors, Sae Byul Lee.
Breast Cancer Res Treat, 2021 Feb 19;. PMID: 33599867
Large Tumor Size is an Indicator for the Timely Administration of Adjuvant Radiotherapy in Luminal Breast Cancer with Positive Lymph Node.
Kai-Yun You, Wei-Liang Zou, +2 authors, He-Rui Yao.
Cancer Manag Res, 2021 Feb 20; 13. PMID: 33603478    Free PMC article.