Journal Article
. 2004 Dec;351(27).
doi: 10.1056/NEJMoa041588.

A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer

Soonmyung Paik 1 Steven Shak  Gong Tang  Chungyeul Kim  Joffre Baker  Maureen Cronin  Frederick L Baehner  Michael G Walker  Drew Watson  Taesung Park  William Hiller  Edwin R Fisher  D Lawrence Wickerham  John Bryant  Norman Wolmark  
  • PMID: 15591335
  •     1799 citations


Background: The likelihood of distant recurrence in patients with breast cancer who have no involved lymph nodes and estrogen-receptor-positive tumors is poorly defined by clinical and histopathological measures.

Methods: We tested whether the results of a reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay of 21 prospectively selected genes in paraffin-embedded tumor tissue would correlate with the likelihood of distant recurrence in patients with node-negative, tamoxifen-treated breast cancer who were enrolled in the National Surgical Adjuvant Breast and Bowel Project clinical trial B-14. The levels of expression of 16 cancer-related genes and 5 reference genes were used in a prospectively defined algorithm to calculate a recurrence score and to determine a risk group (low, intermediate, or high) for each patient.

Results: Adequate RT-PCR profiles were obtained in 668 of 675 tumor blocks. The proportions of patients categorized as having a low, intermediate, or high risk by the RT-PCR assay were 51, 22, and 27 percent, respectively. The Kaplan-Meier estimates of the rates of distant recurrence at 10 years in the low-risk, intermediate-risk, and high-risk groups were 6.8 percent (95 percent confidence interval, 4.0 to 9.6), 14.3 percent (95 percent confidence interval, 8.3 to 20.3), and 30.5 percent (95 percent confidence interval, 23.6 to 37.4). The rate in the low-risk group was significantly lower than that in the high-risk group (P<0.001). In a multivariate Cox model, the recurrence score provided significant predictive power that was independent of age and tumor size (P<0.001). The recurrence score was also predictive of overall survival (P<0.001) and could be used as a continuous function to predict distant recurrence in individual patients.

Conclusions: The recurrence score has been validated as quantifying the likelihood of distant recurrence in tamoxifen-treated patients with node-negative, estrogen-receptor-positive breast cancer.

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Br J Cancer, 2008 Aug 30; 99(5). PMID: 18728668    Free PMC article.
The functional loss of the retinoblastoma tumour suppressor is a common event in basal-like and luminal B breast carcinomas.
Jason I Herschkowitz, Xiaping He, Cheng Fan, Charles M Perou.
Breast Cancer Res, 2008 Sep 11; 10(5). PMID: 18782450    Free PMC article.
Highly Cited.
Identification of a gene signature in cell cycle pathway for breast cancer prognosis using gene expression profiling data.
Jiangang Liu, Andrew Campen, +6 authors, Shuyu Li.
BMC Med Genomics, 2008 Sep 13; 1. PMID: 18786252    Free PMC article.
Translational Research Working Group developmental pathway for biospecimen-based assessment modalities.
Sudhir Srivastava, Joe W Gray, +4 authors, Translational Research Working Group.
Clin Cancer Res, 2008 Sep 17; 14(18). PMID: 18794074    Free PMC article.
Cytochrome P450 2D6 and homeobox 13/interleukin-17B receptor: combining inherited and tumor gene markers for prediction of tamoxifen resistance.
Matthew P Goetz, Vera J Suman, +12 authors, James N Ingle.
Clin Cancer Res, 2008 Sep 17; 14(18). PMID: 18794098    Free PMC article.
On the eve of personalized medicine in oncology.
Timothy J Yeatman, James Mule, William S Dalton, Dan Sullivan.
Cancer Res, 2008 Sep 17; 68(18). PMID: 18794109    Free PMC article.
Outcome prediction for estrogen receptor-positive breast cancer based on postneoadjuvant endocrine therapy tumor characteristics.
Matthew J Ellis, Yu Tao, +9 authors, Mitch Dowsett.
J Natl Cancer Inst, 2008 Sep 25; 100(19). PMID: 18812550    Free PMC article.
Highly Cited.
Validation of biomarker-based risk prediction models.
Jeremy M G Taylor, Donna P Ankerst, Rebecca R Andridge.
Clin Cancer Res, 2008 Oct 03; 14(19). PMID: 18829476    Free PMC article.
Hazard of recurrence and adjuvant treatment effects over time in lymph node-negative breast cancer.
James J Dignam, Vanja Dukic, +3 authors, Norman Wolmark.
Breast Cancer Res Treat, 2008 Oct 03; 116(3). PMID: 18830816    Free PMC article.
Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes.
Golareh Habibi, Samuel Leung, +7 authors, Sandra E Dunn.
Breast Cancer Res, 2008 Oct 18; 10(5). PMID: 18925950    Free PMC article.
Chemosensitivity and stratification by a five monoclonal antibody immunohistochemistry test in the NSABP B14 and B20 trials.
Douglas T Ross, Chung-Yeul Kim, +7 authors, Norman Wolmark.
Clin Cancer Res, 2008 Oct 18; 14(20). PMID: 18927301    Free PMC article.
The half century of clinical trials of the National Surgical Adjuvant Breast And Bowel Project.
D Lawrence Wickerham, Michael J O'Connell, +8 authors, Norman Wolmark.
Semin Oncol, 2008 Oct 22; 35(5). PMID: 18929150    Free PMC article.
New wirings in the survivin networks.
D C Altieri.
Oncogene, 2008 Oct 22; 27(48). PMID: 18931693    Free PMC article.
Current research topics in endocrine therapy for breast cancer.
Hiroko Yamashita.
Int J Clin Oncol, 2008 Oct 24; 13(5). PMID: 18946747
Gene expression profiling of breast cancer.
Ting Bao, Nancy E Davidson.
Adv Surg, 2008 Oct 29; 42. PMID: 18953822    Free PMC article.
Chemotherapy use for hormone receptor-positive, lymph node-negative breast cancer.
Michael J Hassett, Melissa E Hughes, +7 authors, Jane C Weeks.
J Clin Oncol, 2008 Oct 29; 26(34). PMID: 18955448    Free PMC article.
Lost in translation: problems and pitfalls in translating laboratory observations to clinical utility.
Richard Simon.
Eur J Cancer, 2008 Nov 04; 44(18). PMID: 18977655    Free PMC article.
Robust prognostic value of a knowledge-based proliferation signature across large patient microarray studies spanning different cancer types.
M H W Starmans, B Krishnapuram, +8 authors, P Lambin.
Br J Cancer, 2008 Nov 06; 99(11). PMID: 18985037    Free PMC article.
Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer.
Charles Swanton, Zoltan Szallasi, James D Brenton, Julian Downward.
Breast Cancer Res, 2008 Nov 07; 10(5). PMID: 18986507    Free PMC article.
A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer.
Fabien Reyal, Martin H van Vliet, +10 authors, Lodewyk F A Wessels.
Breast Cancer Res, 2008 Nov 19; 10(6). PMID: 19014521    Free PMC article.
Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature.
Andrew Tutt, Alice Wang, +21 authors, Fred Waldman.
BMC Cancer, 2008 Nov 26; 8. PMID: 19025599    Free PMC article.
Ebp1 expression in benign and malignant prostate.
Philippe O Gannon, Ismaël Hervé Koumakpayi, +3 authors, Fred Saad.
Cancer Cell Int, 2008 Nov 26; 8. PMID: 19025630    Free PMC article.
A functional Notch-survivin gene signature in basal breast cancer.
Connie W Lee, Karl Simin, +5 authors, Dario C Altieri.
Breast Cancer Res, 2008 Nov 26; 10(6). PMID: 19025652    Free PMC article.
Gene expression variation between distinct areas of breast cancer measured from paraffin-embedded tissue cores.
Martina Schobesberger, Anna Baltzer, +4 authors, Rolf Jaggi.
BMC Cancer, 2008 Nov 27; 8. PMID: 19032762    Free PMC article.
Educational and social-ethical issues in the pursuit of molecular medicine.
Panagiotis A Konstantinopoulos, Michalis V Karamouzis, Athanasios G Papavassiliou.
Mol Med, 2008 Dec 02; 15(1-2). PMID: 19043478    Free PMC article.
BAG-1 predicts patient outcome and tamoxifen responsiveness in ER-positive invasive ductal carcinoma of the breast.
E K A Millar, L R Anderson, +9 authors, A J Butt.
Br J Cancer, 2008 Dec 11; 100(1). PMID: 19066611    Free PMC article.
Advances in breast cancer: pathways to personalized medicine.
Olufunmilayo I Olopade, Tatyana A Grushko, Rita Nanda, Dezheng Huo.
Clin Cancer Res, 2008 Dec 18; 14(24). PMID: 19088015    Free PMC article.
Confirmation of gene expression-based prediction of survival in non-small cell lung cancer.
Nancy L Guo, Ying-Wooi Wan, +10 authors, Yong Qian.
Clin Cancer Res, 2008 Dec 18; 14(24). PMID: 19088038    Free PMC article.
Mechanisms of metastasis.
Kent W Hunter, Nigel P S Crawford, Jude Alsarraj.
Breast Cancer Res, 2009 Jan 06; 10 Suppl 1. PMID: 19091006    Free PMC article.
Clinical impact of high-throughput gene expression studies in lung cancer.
Jennifer Beane, Avrum Spira, Marc E Lenburg.
J Thorac Oncol, 2008 Dec 20; 4(1). PMID: 19096318    Free PMC article.
EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer.
Alexandra M Pietersen, Hugo M Horlings, +7 authors, Maarten van Lohuizen.
Breast Cancer Res, 2008 Dec 23; 10(6). PMID: 19099573    Free PMC article.
The gene expression signature of genomic instability in breast cancer is an independent predictor of clinical outcome.
Jens K Habermann, Jana Doering, +12 authors, Thomas Ried.
Int J Cancer, 2008 Dec 23; 124(7). PMID: 19101988    Free PMC article.
Expression of centromere protein F (CENP-F) associated with higher FDG uptake on PET/CT, detected by cDNA microarray, predicts high-risk patients with primary breast cancer.
Shigeto Ueda, Nobuo Kondoh, +10 authors, Hidetaka Mochizuki.
BMC Cancer, 2008 Dec 24; 8. PMID: 19102762    Free PMC article.
The origins of breast cancer prognostic gene expression profiles.
Luanne Lukes, Nigel P S Crawford, Renard Walker, Kent W Hunter.
Cancer Res, 2009 Jan 02; 69(1). PMID: 19118016    Free PMC article.
Recommendations from the EGAPP Working Group: can tumor gene expression profiling improve outcomes in patients with breast cancer?
Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group.
Genet Med, 2009 Jan 07; 11(1). PMID: 19125125    Free PMC article.
Markers of endocrine sensitivity.
Daniel F Hayes.
Breast Cancer Res, 2009 Jan 16; 10 Suppl 4. PMID: 19128431    Free PMC article.
The utility of conventional and molecular pathology in managing breast cancer.
D Craig Allred.
Breast Cancer Res, 2009 Jan 16; 10 Suppl 4. PMID: 19128442    Free PMC article.
Tailoring to RB: tumour suppressor status and therapeutic response.
Erik S Knudsen, Karen E Knudsen.
Nat Rev Cancer, 2009 Jan 15; 8(9). PMID: 19143056    Free PMC article.
Highly Cited. Review.
Dynamic modularity in protein interaction networks predicts breast cancer outcome.
Ian W Taylor, Rune Linding, +7 authors, Jeffrey L Wrana.
Nat Biotechnol, 2009 Feb 03; 27(2). PMID: 19182785
Highly Cited.
Selecting control genes for RT-QPCR using public microarray data.
Vlad Popovici, Darlene R Goldstein, +3 authors, Pratyaksha Wirapati.
BMC Bioinformatics, 2009 Feb 04; 10. PMID: 19187545    Free PMC article.
Development and Validation of Biomarker Classifiers for Treatment Selection.
Richard Simon.
J Stat Plan Inference, 2009 Feb 05; 138(2). PMID: 19190712    Free PMC article.
Molecular changes in primary breast tumors and the Nottingham Histologic Score.
Rachel E Ellsworth, Jeffrey A Hooke, +2 authors, Craig D Shriver.
Pathol Oncol Res, 2009 Feb 06; 15(4). PMID: 19194786
Supervised risk predictor of breast cancer based on intrinsic subtypes.
Joel S Parker, Michael Mullins, +17 authors, Philip S Bernard.
J Clin Oncol, 2009 Feb 11; 27(8). PMID: 19204204    Free PMC article.
Highly Cited.
Breast cancer subtypes and response to docetaxel in node-positive breast cancer: use of an immunohistochemical definition in the BCIRG 001 trial.
Judith Hugh, John Hanson, +11 authors, Charles Vogel.
J Clin Oncol, 2009 Feb 11; 27(8). PMID: 19204205    Free PMC article.
Highly Cited.
[Genome-wide expression profiling as a clinical tool: are we there yet?].
F C Geyer, T Decker, J S Reis-Filho.
Pathologe, 2009 Feb 17; 30(2). PMID: 19219435
Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer.
Scott A Waldman, Terry Hyslop, +6 authors, David S Weinberg.
JAMA, 2009 Feb 20; 301(7). PMID: 19224751    Free PMC article.
Biological convergence of cancer signatures.
Xavier Solé, Núria Bonifaci, +11 authors, Miguel Angel Pujana.
PLoS One, 2009 Feb 21; 4(2). PMID: 19229342    Free PMC article.
Genomancy: predicting tumour response to cancer therapy based on the oracle of genetics.
P D Williams, J K Lee, D Theodorescu.
Curr Oncol, 2009 Feb 21; 16(1). PMID: 19229372    Free PMC article.
Reduced expression of a gene proliferation signature is associated with enhanced malignancy in colon cancer.
A Anjomshoaa, Y-H Lin, +10 authors, A E Reeve.
Br J Cancer, 2009 Feb 25; 99(6). PMID: 19238634    Free PMC article.
Cell-cycle-phase progression analysis identifies unique phenotypes of major prognostic and predictive significance in breast cancer.
M Loddo, S R Kingsbury, +10 authors, G H Williams.
Br J Cancer, 2009 Feb 26; 100(6). PMID: 19240714    Free PMC article.
Mutation detection by real-time PCR: a simple, robust and highly selective method.
John Morlan, Joffre Baker, Dominick Sinicropi.
PLoS One, 2009 Feb 26; 4(2). PMID: 19240792    Free PMC article.
Preservation of fertility in patients with cancer.
Jacqueline S Jeruss, Teresa K Woodruff.
N Engl J Med, 2009 Feb 28; 360(9). PMID: 19246362    Free PMC article.
Highly Cited. Review.
Utilizing the molecular gateway: the path to personalized cancer management.
Jonathan B Overdevest, Dan Theodorescu, Jae K Lee.
Clin Chem, 2009 Feb 28; 55(4). PMID: 19246616    Free PMC article.
Successful pregnancy after breast cancer therapy: dream or reality?
Konstantinos Kontzoglou, Michael Stamatakos, +3 authors, Michael Safioleas.
Int Semin Surg Oncol, 2009 Mar 04; 6. PMID: 19254357    Free PMC article.
Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue.
Dung-Tsa Chen, Aejaz Nasir, +12 authors, Timothy Yeatman.
Breast Cancer Res Treat, 2009 Mar 07; 119(2). PMID: 19266279    Free PMC article.
A radiation-derived gene expression signature predicts clinical outcome for breast cancer patients.
Brian D Piening, Pei Wang, Aravind Subramanian, Amanda G Paulovich.
Radiat Res, 2009 Mar 10; 171(2). PMID: 19267539    Free PMC article.
The tspair package for finding top scoring pair classifiers in R.
Jeffrey T Leek.
Bioinformatics, 2009 Mar 12; 25(9). PMID: 19276151    Free PMC article.
MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment.
Sean P Pitroda, Nikolai N Khodarev, +2 authors, Ralph R Weichselbaum.
Proc Natl Acad Sci U S A, 2009 Mar 18; 106(14). PMID: 19289846    Free PMC article.
Factors influencing the statistical power of complex data analysis protocols for molecular signature development from microarray data.
Constantin F Aliferis, Alexander Statnikov, +3 authors, Frank E Harrell.
PLoS One, 2009 Mar 18; 4(3). PMID: 19290050    Free PMC article.
A compact VEGF signature associated with distant metastases and poor outcomes.
Zhiyuan Hu, Cheng Fan, +10 authors, Charles M Perou.
BMC Med, 2009 Mar 18; 7. PMID: 19291283    Free PMC article.
High cyclin B1 expression is associated with poor survival in breast cancer.
K Aaltonen, R-M Amini, +4 authors, C Blomqvist.
Br J Cancer, 2009 Mar 19; 100(7). PMID: 19293801    Free PMC article.
Prevalence, morphologic features and proliferation indices of breast carcinoma molecular classes using immunohistochemical surrogate markers.
Rohit Bhargava, Joan Striebel, +4 authors, David J Dabbs.
Int J Clin Exp Pathol, 2009 Mar 19; 2(5). PMID: 19294003    Free PMC article.
Prediction of breast cancer metastasis by genomic profiling: where do we stand?
Ulrich Pfeffer, Francesco Romeo, Douglas M Noonan, Adriana Albini.
Clin Exp Metastasis, 2009 Mar 25; 26(6). PMID: 19308665    Free PMC article.
Transcriptome analysis of liver cancer: ready for the clinic?
Xin Wei Wang, Snorri S Thorgeirsson.
J Hepatol, 2009 Mar 31; 50(5). PMID: 19328580    Free PMC article.
A multi-marker assay to distinguish malignant melanomas from benign nevi.
Mohammed Kashani-Sabet, Javier Rangel, +7 authors, Richard W Sagebiel.
Proc Natl Acad Sci U S A, 2009 Apr 01; 106(15). PMID: 19332774    Free PMC article.
Distant metastasis: not out of reach any more.
François Bertucci, Daniel Birnbaum.
J Biol, 2009 Apr 07; 8(3). PMID: 19344492    Free PMC article.
Breaking down barriers: the importance of the stromal microenvironment in acquiring invasiveness in young women's breast cancer.
Pepper Schedin, Virginia Borges.
Breast Cancer Res, 2009 Apr 07; 11(2). PMID: 19344495    Free PMC article.
Gene expression profiles and breast cancer metastasis: a genetic perspective.
Kent W Hunter, Jude Alsarraj.
Clin Exp Metastasis, 2009 Apr 07; 26(6). PMID: 19347591    Free PMC article.
Genomics of lung cancer.
Alain C Borczuk, Rebecca L Toonkel, Charles A Powell.
Proc Am Thorac Soc, 2009 Apr 08; 6(2). PMID: 19349483    Free PMC article.
Quantitative assessment of tissue biomarkers and construction of a model to predict outcome in breast cancer using multiple imputation.
John W Emerson, Marisa Dolled-Filhart, +2 authors, David P Tuck.
Cancer Inform, 2009 Apr 09; 7. PMID: 19352457    Free PMC article.
A health services research agenda for cellular, molecular and genomic technologies in cancer care.
Louise Wideroff, Kathryn A Phillips, +16 authors, Joan Scott.
Public Health Genomics, 2009 Apr 16; 12(4). PMID: 19367091    Free PMC article.
Molecular classification of solid tumours: towards pathway-driven therapeutics.
C Swanton, C Caldas.
Br J Cancer, 2009 Apr 16; 100(10). PMID: 19367275    Free PMC article.
Metastatic gene signatures and emerging novel prognostic tests in the management of early stage breast cancer.
Attila Tordai, Cornelia Liedtke, Lajos Pusztai.
Clin Exp Metastasis, 2009 Apr 22; 26(7). PMID: 19381845
The MINDACT trial: the first prospective clinical validation of a genomic tool.
Fatima Cardoso, Martine Piccart-Gebhart, +2 authors, TRANSBIG Consortium.
Mol Oncol, 2007 Dec 01; 1(3). PMID: 19383299    Free PMC article.
Biomarkers in oncology drug development.
Darren R Hodgson, Robin D Whittaker, +2 authors, Glen Clack.
Mol Oncol, 2009 Apr 23; 3(1). PMID: 19383364    Free PMC article.
Targeted proteomic strategy for clinical biomarker discovery.
Ralph Schiess, Bernd Wollscheid, Ruedi Aebersold.
Mol Oncol, 2009 Apr 23; 3(1). PMID: 19383365    Free PMC article.
Highly Cited. Review.
Development of a multiplex quantitative PCR signature to predict progression in non-muscle-invasive bladder cancer.
Rou Wang, David S Morris, +8 authors, Arul M Chinnaiyan.
Cancer Res, 2009 Apr 23; 69(9). PMID: 19383904    Free PMC article.
Molecular characterization of apocrine carcinoma of the breast: validation of an apocrine protein signature in a well-defined cohort.
Julio E Celis, Teresa Cabezón, +7 authors, Fritz Rank.
Mol Oncol, 2009 Apr 28; 3(3). PMID: 19393583    Free PMC article.
Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma.
Gavin J Gordon, Lingsheng Dong, +9 authors, Raphael Bueno.
J Natl Cancer Inst, 2009 Apr 30; 101(9). PMID: 19401544    Free PMC article.
Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer.
Jocelyne Jacquemier, Emmanuelle Charafe-Jauffret, +6 authors, Daniel Birnbaum.
Breast Cancer Res, 2009 May 02; 11(2). PMID: 19405945    Free PMC article.
Genomic and proteomic biomarkers for cancer: a multitude of opportunities.
Michael A Tainsky.
Biochim Biophys Acta, 2009 May 02; 1796(2). PMID: 19406210    Free PMC article.
Convergence of biomarkers, bioinformatics and nanotechnology for individualized cancer treatment.
John H Phan, Richard A Moffitt, +4 authors, May D Wang.
Trends Biotechnol, 2009 May 05; 27(6). PMID: 19409634    Free PMC article.
Recent advances in systemic therapy: new diagnostics and biological predictors of outcome in early breast cancer.
Catherine Oakman, Silvia Bessi, +3 authors, Angelo Di Leo.
Breast Cancer Res, 2009 May 14; 11(2). PMID: 19435470    Free PMC article.
Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer.
Maggie C U Cheang, Stephen K Chia, +10 authors, Torsten O Nielsen.
J Natl Cancer Inst, 2009 May 14; 101(10). PMID: 19436038    Free PMC article.
Highly Cited.
The role of cathepsins in involution and breast cancer.
Christine J Watson, Peter A Kreuzaler.
J Mammary Gland Biol Neoplasia, 2009 May 14; 14(2). PMID: 19437107
Effects of sample size on robustness and prediction accuracy of a prognostic gene signature.
Seon-Young Kim.
BMC Bioinformatics, 2009 May 19; 10. PMID: 19445687    Free PMC article.
Challenges in the analysis of mass-throughput data: a technical commentary from the statistical machine learning perspective.
Constantin F Aliferis, Alexander Statnikov, Ioannis Tsamardinos.
Cancer Inform, 2007 Jan 01; 2. PMID: 19458765    Free PMC article.
Detecting outlier microarray arrays by correlation and percentage of outliers spots.
Song Yang, Xiang Guo, +6 authors, Hai Hu.
Cancer Inform, 2007 Jan 01; 2. PMID: 19458777    Free PMC article.
Expression of ER-{alpha}36, a novel variant of estrogen receptor {alpha}, and resistance to tamoxifen treatment in breast cancer.
Liang Shi, Bin Dong, +9 authors, Yuntao Xie.
J Clin Oncol, 2009 Jun 03; 27(21). PMID: 19487384    Free PMC article.
Gene expression-based prognostic and predictive markers for breast cancer: a primer for practicing pathologists.
Chungyeul Kim, Yusuke Taniyama, Soonmyung Paik.
Arch Pathol Lab Med, 2009 Jun 06; 133(6). PMID: 19492877    Free PMC article.
A longitudinal study of gene expression in healthy individuals.
Chris Karlovich, Guillemette Duchateau-Nguyen, +8 authors, John P Caulfield.
BMC Med Genomics, 2009 Jun 09; 2. PMID: 19500411    Free PMC article.
STAT1 pathway mediates amplification of metastatic potential and resistance to therapy.
Nikolai N Khodarev, Paul Roach, +11 authors, Ralph R Weichselbaum.
PLoS One, 2009 Jun 09; 4(6). PMID: 19503789    Free PMC article.
Genomic predictors of outcome and treatment response in breast cancer.
Lara Dunn, Angela Demichele.
Mol Diagn Ther, 2009 Jun 23; 13(2). PMID: 19537843
Comparison of prognostic gene profiles using qRT-PCR in paraffin samples: a retrospective study in patients with early breast cancer.
Enrique Espinosa, Iker Sánchez-Navarro, +9 authors, Juan Angel Fresno Vara.
PLoS One, 2009 Jun 24; 4(6). PMID: 19547727    Free PMC article.
Verification of a prolonged untreated natural history of breast cancer by the multigene assay.
Tadeja Urbas, Neal Agee, Marcia E Bouton, Ian K Komenaka.
Med Oncol, 2009 Jun 24; 27(3). PMID: 19548125
Gene expression profiling identifies activated growth factor signaling in poor prognosis (Luminal-B) estrogen receptor positive breast cancer.
Sherene Loi, Christos Sotiriou, +5 authors, Grant A McArthur.
BMC Med Genomics, 2009 Jun 26; 2. PMID: 19552798    Free PMC article.
A Bayesian hierarchical nonlinear model for assessing the association between genetic variation and drug cytotoxicity.
Brooke L Fridley, Gregory Jenkins, Daniel J Schaid, Liewei Wang.
Stat Med, 2009 Jul 03; 28(21). PMID: 19572260    Free PMC article.
Breast cancer subtypes based on ER/PR and Her2 expression: comparison of clinicopathologic features and survival.
Adedayo A Onitilo, Jessica M Engel, Robert T Greenlee, Bickol N Mukesh.
Clin Med Res, 2009 Jul 04; 7(1-2). PMID: 19574486    Free PMC article.
Highly Cited.
Current molecular diagnostics of breast cancer and the potential incorporation of microRNA.
Christine K Zoon, Elizabeth Q Starker, +3 authors, Michael A Tangrea.
Expert Rev Mol Diagn, 2009 Jul 08; 9(5). PMID: 19580430    Free PMC article.
Identification of novel reference genes using multiplatform expression data and their validation for quantitative gene expression analysis.
Mi Jeong Kwon, Ensel Oh, +8 authors, Young Kee Shin.
PLoS One, 2009 Jul 09; 4(7). PMID: 19584937    Free PMC article.
Postoperative endocrine therapy for invasive breast cancer.
Leisha A Emens, Nancy E Davidson.
Cancer Treat Res, 2009 Jul 14; 151. PMID: 19593511    Free PMC article.
Clinical trial designs for predictive biomarker validation: theoretical considerations and practical challenges.
Sumithra J Mandrekar, Daniel J Sargent.
J Clin Oncol, 2009 Jul 15; 27(24). PMID: 19597023    Free PMC article.
Highly Cited.
Low expression of a few genes indicates good prognosis in estrogen receptor positive breast cancer.
Steven Buechler.
BMC Cancer, 2009 Jul 22; 9. PMID: 19619298    Free PMC article.
Genomic advances and their impact on clinical trial design.
Sumithra J Mandrekar, Daniel J Sargent.
Genome Med, 2009 Jul 30; 1(7). PMID: 19638184    Free PMC article.
MicroRNAs as Novel Biomarkers for Breast Cancer.
H M Heneghan, N Miller, +2 authors, M J Kerin.
J Oncol, 2009 Jul 30; 2009. PMID: 19639033    Free PMC article.
Pharmacogenetics of solid tumors: directed therapy in breast, lung, and colorectal cancer: a paper from the 2008 william beaumont hospital symposium on molecular pathology.
Christine L H Snozek, Dennis J O'Kane, Alicia Algeciras-Schimnich.
J Mol Diagn, 2009 Aug 01; 11(5). PMID: 19644023    Free PMC article.
Evaluation of microtubule-associated protein-Tau expression as a prognostic and predictive marker in the NSABP-B 28 randomized clinical trial.
Lajos Pusztai, Jong-Hyeon Jeong, +8 authors, W Fraser Symmans.
J Clin Oncol, 2009 Aug 12; 27(26). PMID: 19667268    Free PMC article.
Mechanisms and pathways of bone metastasis: challenges and pitfalls of performing molecular research on patient samples.
T R Cawthorn, E Amir, +7 authors, M Clemons.
Clin Exp Metastasis, 2009 Aug 22; 26(8). PMID: 19697143
Analysis of DNA microarray expression data.
Richard Simon.
Best Pract Res Clin Haematol, 2009 Aug 25; 22(2). PMID: 19698933    Free PMC article.
Biological determinants of endocrine resistance in breast cancer.
Elizabeth A Musgrove, Robert L Sutherland.
Nat Rev Cancer, 2009 Aug 25; 9(9). PMID: 19701242
Highly Cited. Review.
Growth factor receptor-bound protein-7 (Grb7) as a prognostic marker and therapeutic target in breast cancer.
Y Nadler, A M González, +3 authors, Y Kluger.
Ann Oncol, 2009 Sep 01; 21(3). PMID: 19717535    Free PMC article.
Genetic characterization of breast cancer and implications for clinical management.
Felipe C Geyer, Maria A Lopez-Garcia, Maryou B Lambros, Jorge S Reis-Filho.
J Cell Mol Med, 2009 Sep 17; 13(10). PMID: 19754664    Free PMC article.
Molecular clustering of endometrial carcinoma based on estrogen-induced gene expression.
Shannon N Westin, Russell R Broaddus, +8 authors, David S Loose.
Cancer biology & therapy, 2009 Sep 17; 8(22). PMID: 19755863    Free PMC article.
PAPAyA: a platform for breast cancer biomarker signature discovery, evaluation and assessment.
Angel Janevski, Sitharthan Kamalakaran, +2 authors, Nevenka Dimitrova.
BMC Bioinformatics, 2009 Sep 26; 10 Suppl 9. PMID: 19761577    Free PMC article.
Immutable functional attributes of histologic grade revealed by context-independent gene expression in primary breast cancer cells.
Shanaz H Dairkee, Aejaz Sayeed, +6 authors, Dan H Moore.
Cancer Res, 2009 Oct 01; 69(19). PMID: 19789341    Free PMC article.
Alzheimer's disease biomarker discovery in symptomatic and asymptomatic patients: experimental approaches and future clinical applications.
Lap Ho, Hayley Fivecoat, Jun Wang, Giulio Maria Pasinetti.
Exp Gerontol, 2009 Oct 03; 45(1). PMID: 19796674    Free PMC article.
Making the case for molecular staging of malignant pleural mesothelioma.
Raphael Bueno.
Semin Thorac Cardiovasc Surg, 2009 Oct 14; 21(2). PMID: 19822292    Free PMC article.
Preinvasive breast cancer.
Dennis C Sgroi.
Annu Rev Pathol, 2009 Oct 15; 5. PMID: 19824828    Free PMC article.
Prognostic and predictive factors and genetic analysis of early breast cancer.
Miguel Martín, Fernando González Palacios, +2 authors, José Schneider.
Clin Transl Oncol, 2009 Oct 16; 11(10). PMID: 19828405
A multi-center phase II evaluation of the small molecule survivin suppressor YM155 in patients with unresectable stage III or IV melanoma.
Karl D Lewis, Wolfram Samlowski, +6 authors, Rene Gonzalez.
Invest New Drugs, 2009 Oct 16; 29(1). PMID: 19830389
Gene expression profile assays as predictors of distant recurrence-free survival in early-stage breast cancer.
Nicole M Kuderer, Gary H Lyman.
Cancer Invest, 2009 Oct 17; 27(9). PMID: 19832034    Free PMC article.
A 7 gene expression score predicts for radiation response in cancer cervix.
Thangarajan Rajkumar, Neelakantan Vijayalakshmi, +4 authors, Lavanya Nambaru.
BMC Cancer, 2009 Oct 17; 9. PMID: 19832977    Free PMC article.
Melanoma prognostic model using tissue microarrays and genetic algorithms.
Bonnie E Gould Rothberg, Aaron J Berger, +7 authors, David L Rimm.
J Clin Oncol, 2009 Nov 04; 27(34). PMID: 19884546    Free PMC article.
Breast cancer in young women: poor survival despite intensive treatment.
Hanna Fredholm, Sonja Eaker, +3 authors, Henrik Lindman.
PLoS One, 2009 Nov 13; 4(11). PMID: 19907646    Free PMC article.
Highly Cited.
Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer.
J Joshua Smith, Natasha G Deane, +16 authors, R Daniel Beauchamp.
Gastroenterology, 2009 Nov 17; 138(3). PMID: 19914252    Free PMC article.
Highly Cited.
Adjuvant endocrine therapy for premenopausal women with breast cancer.
Shannon Puhalla, Adam Brufsky, Nancy Davidson.
Breast, 2009 Nov 17; 18 Suppl 3. PMID: 19914530    Free PMC article.
Impact of biospecimens handling on biomarker research in breast cancer.
Loris De Cecco, Valeria Musella, +6 authors, Maria Grazia Daidone.
BMC Cancer, 2009 Nov 26; 9. PMID: 19930681    Free PMC article.
Evaluation of Oncotype DX Recurrence Score as a prognostic factor in Japanese women with estrogen receptor-positive, node-negative primary Stage I or IIA breast cancer.
Kyoko Yorozuya, Toru Takeuchi, +9 authors, Shogo Kikuchi.
J Cancer Res Clin Oncol, 2009 Dec 01; 136(6). PMID: 19946706
[Beyond staging, typing and grading. New challenges in breast cancer pathology].
H H Kreipe, P Ahrens, +2 authors, F Länger.
Pathologe, 2009 Dec 02; 31(1). PMID: 19949797
Relationship between Topoisomerase 2A RNA Expression and Recurrence after Adjuvant Chemotherapy for Breast Cancer.
Joseph A Sparano, Lori J Goldstein, +12 authors, Robert Gray.
Clin Cancer Res, 2009 Dec 10; 15(24). PMID: 19996222    Free PMC article.
Taxanes: optimizing adjuvant chemotherapy for early-stage breast cancer.
Philippe L Bedard, Angelo Di Leo, Martine J Piccart-Gebhart.
Nat Rev Clin Oncol, 2009 Dec 10; 7(1). PMID: 19997076
Survival prediction from clinico-genomic models--a comparative study.
Hege M Bøvelstad, Ståle Nygård, Ornulf Borgan.
BMC Bioinformatics, 2009 Dec 17; 10. PMID: 20003386    Free PMC article.
Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial.
Kathy S Albain, William E Barlow, +20 authors, Breast Cancer Intergroup of North America.
Lancet Oncol, 2009 Dec 17; 11(1). PMID: 20005174    Free PMC article.
Highly Cited.
Molecular predictors of response to trastuzumab and lapatinib in breast cancer.
Francisco J Esteva, Dihua Yu, Mien-Chie Hung, Gabriel N Hortobagyi.
Nat Rev Clin Oncol, 2009 Dec 23; 7(2). PMID: 20027191
Radiation impact in breast cancer.
Joseph Ragaz.
Breast Cancer Res, 2010 Jan 20; 11 Suppl 3. PMID: 20030865    Free PMC article.
Tailored targeted therapy for all: a realistic and worthwhile objective against.
Kathleen I Pritchard.
Breast Cancer Res, 2010 Jan 20; 11 Suppl 3. PMID: 20030883    Free PMC article.
Application of RT-PCR in formalin-fixed and paraffin-embedded lung cancer tissues.
Fan Zhang, Zhuo-min Wang, +6 authors, Qing-hua Zhou.
Acta Pharmacol Sin, 2009 Dec 29; 31(1). PMID: 20037605    Free PMC article.
Sources of bias in specimens for research about molecular markers for cancer.
David F Ransohoff, Margaret L Gourlay.
J Clin Oncol, 2009 Dec 30; 28(4). PMID: 20038718    Free PMC article.
Role of axillary clearance after a tumor-positive sentinel node in the administration of adjuvant therapy in early breast cancer.
Marieke E Straver, Philip Meijnen, +11 authors, Emiel J T Rutgers.
J Clin Oncol, 2009 Dec 30; 28(5). PMID: 20038733    Free PMC article.
Predictive value of progression-related gene classifier in primary non-muscle invasive bladder cancer.
Wun-Jae Kim, Eun-Jung Kim, +10 authors, Suk-Chul Bae.
Mol Cancer, 2010 Jan 12; 9. PMID: 20059769    Free PMC article.
Highly Cited.
Effect of training-sample size and classification difficulty on the accuracy of genomic predictors.
Vlad Popovici, Weijie Chen, +15 authors, Lajos Pusztai.
Breast Cancer Res, 2010 Jan 13; 12(1). PMID: 20064235    Free PMC article.
Association between the 21-gene recurrence score assay and risk of locoregional recurrence in node-negative, estrogen receptor-positive breast cancer: results from NSABP B-14 and NSABP B-20.
Eleftherios P Mamounas, Gong Tang, +7 authors, Norman Wolmark.
J Clin Oncol, 2010 Jan 13; 28(10). PMID: 20065188    Free PMC article.
Highly Cited.
Multidisciplinary approach of early breast cancer: the biology applied to radiation oncology.
Céline Bourgier, Mahmut Ozsahin, David Azria.
Radiat Oncol, 2010 Jan 16; 5. PMID: 20074364    Free PMC article.
3'-end sequencing for expression quantification (3SEQ) from archival tumor samples.
Andrew H Beck, Ziming Weng, +8 authors, Robert B West.
PLoS One, 2010 Jan 26; 5(1). PMID: 20098735    Free PMC article.
CYP2D6 testing in breast cancer: ready for prime time?
Nicole M Kuderer, Jeffrey Peppercorn.
Oncology (Williston Park), 2010 Feb 04; 23(14). PMID: 20120834    Free PMC article.
Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression.
Alessio Nencioni, Michele Cea, +8 authors, Alberto Ballestrero.
PLoS One, 2010 Feb 04; 5(2). PMID: 20126311    Free PMC article.
A population-based gene signature is predictive of breast cancer survival and chemoresponse.
Shruti Rathnagiriswaran, Ying-Wooi Wan, +3 authors, Nancy L Guo.
Int J Oncol, 2010 Feb 04; 36(3). PMID: 20126981    Free PMC article.
Biologic predictors of extension of oligoarticular juvenile idiopathic arthritis as determined from synovial fluid cellular composition and gene expression.
Patricia J Hunter, Kiran Nistala, +4 authors, Lucy R Wedderburn.
Arthritis Rheum, 2010 Feb 04; 62(3). PMID: 20127724    Free PMC article.
MYC regulation of a "poor-prognosis" metastatic cancer cell state.
Anita Wolfer, Ben S Wittner, +14 authors, Sridhar Ramaswamy.
Proc Natl Acad Sci U S A, 2010 Feb 06; 107(8). PMID: 20133671    Free PMC article.
Molecular risk assessment of BIG 1-98 participants by expression profiling using RNA from archival tissue.
Janine Antonov, Vlad Popovici, +9 authors, Rolf Jaggi.
BMC Cancer, 2010 Feb 11; 10. PMID: 20144231    Free PMC article.
A multigene predictor of outcome in glioblastoma.
Howard Colman, Li Zhang, +16 authors, Ken Aldape.
Neuro Oncol, 2010 Feb 13; 12(1). PMID: 20150367    Free PMC article.
Highly Cited.
Bimodal gene expression patterns in breast cancer.
Marina Bessarabova, Eugene Kirillov, +3 authors, Tatiana Nikolskaya.
BMC Genomics, 2010 Mar 03; 11 Suppl 1. PMID: 20158879    Free PMC article.
Comparison of breast cancer to healthy control tissue discovers novel markers with potential for prognosis and early detection.
Michèl Schummer, Ann Green, +6 authors, Nicole Urban.
PLoS One, 2010 Feb 18; 5(2). PMID: 20161755    Free PMC article.
FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer.
Nicholas Turner, Alex Pearson, +12 authors, Alan Ashworth.
Cancer Res, 2010 Feb 25; 70(5). PMID: 20179196    Free PMC article.
Highly Cited.
Gene expression in histologically normal epithelium from breast cancer patients and from cancer-free prophylactic mastectomy patients shares a similar profile.
K Graham, A de las Morenas, +10 authors, C L Rosenberg.
Br J Cancer, 2010 Mar 04; 102(8). PMID: 20197764    Free PMC article.
Comparison of microarray-based RNA expression with ELISA-based protein determination of HER2, uPA and PAI-1 in tumour tissue of patients with breast cancer and relation to outcome.
Isabell D Witzel, Karin Milde-Langosch, +6 authors, Volkmar Müller.
J Cancer Res Clin Oncol, 2010 Mar 06; 136(11). PMID: 20204407
LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer.
Yoon-La Choi, Melanie Bocanegra, +6 authors, Jonathan R Pollack.
Cancer Res, 2010 Mar 11; 70(6). PMID: 20215510    Free PMC article.
Transcriptional pathway signatures predict MEK addiction and response to selumetinib (AZD6244).
Jonathan R Dry, Sandra Pavey, +26 authors, Paul D Smith.
Cancer Res, 2010 Mar 11; 70(6). PMID: 20215513    Free PMC article.
Highly Cited.
Predictors of tumor progression during neoadjuvant chemotherapy in breast cancer.
Abigail S Caudle, Ana M Gonzalez-Angulo, +7 authors, Funda Meric-Bernstam.
J Clin Oncol, 2010 Mar 17; 28(11). PMID: 20231683    Free PMC article.
Clinical trials for predictive medicine: new challenges and paradigms.
Richard Simon.
Clin Trials, 2010 Mar 27; 7(5). PMID: 20338899    Free PMC article.
Protein interaction network underpins concordant prognosis among heterogeneous breast cancer signatures.
James Chen, Lee Sam, +5 authors, Yves A Lussier.
J Biomed Inform, 2010 Mar 31; 43(3). PMID: 20350617    Free PMC article.
Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery.
Sabine Tejpar, Monica Bertagnolli, +18 authors, Arnaud Roth.
Oncologist, 2010 Mar 31; 15(4). PMID: 20350999    Free PMC article.
Oncologists' recommendations for adjuvant therapy in hormone receptor-positive breast cancer patients of varying age and health status.
Arash Naeim, F Lennie Wong, Sumanta K Pal, Arti Hurria.
Clin Breast Cancer, 2010 Apr 01; 10(2). PMID: 20353934    Free PMC article.
Clinical trial designs for evaluating the medical utility of prognostic and predictive biomarkers in oncology.
Richard Simon.
Per Med, 2010 Apr 13; 7(1). PMID: 20383292    Free PMC article.
Use of type I interferon-inducible mRNAs as pharmacodynamic markers and potential diagnostic markers in trials with sifalimumab, an anti-IFNα antibody, in systemic lupus erythematosus.
Yihong Yao, Brandon W Higgs, +2 authors, Bahija Jallal.
Arthritis Res Ther, 2010 Apr 16; 12 Suppl 1. PMID: 20392292    Free PMC article.
Predictive biomarker validation in practice: lessons from real trials.
Sumithra J Mandrekar, Daniel J Sargent.
Clin Trials, 2010 Apr 16; 7(5). PMID: 20392785    Free PMC article.
American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer.
M Elizabeth H Hammond, Daniel F Hayes, +29 authors, Antonio C Wolff.
J Clin Oncol, 2010 Apr 21; 28(16). PMID: 20404251    Free PMC article.
Highly Cited. Systematic Review.
Cost-effectiveness analysis of recurrence score-guided treatment using a 21-gene assay in early breast cancer.
Daphne T Tsoi, Miho Inoue, +2 authors, Kathleen I Pritchard.
Oncologist, 2010 Apr 28; 15(5). PMID: 20421264    Free PMC article.
Review of the clinical studies using the 21-gene assay.
Catherine M Kelly, Ellen Warner, +2 authors, Kathleen I Pritchard.
Oncologist, 2010 Apr 28; 15(5). PMID: 20421266    Free PMC article.
What should physicians look for in evaluating prognostic gene-expression signatures?
Jyothi Subramanian, Richard Simon.
Nat Rev Clin Oncol, 2010 Apr 28; 7(6). PMID: 20421890
Personalized medicine in oncology: the future is now.
Richard L Schilsky.
Nat Rev Drug Discov, 2010 May 01; 9(5). PMID: 20431568
Molecular markers to individualize adjuvant therapy for colon cancer.
Tara Gangadhar, Richard L Schilsky.
Nat Rev Clin Oncol, 2010 May 05; 7(6). PMID: 20440283
Gene-expression-based prognostic assays for breast cancer.
Chungyeul Kim, Soonmyung Paik.
Nat Rev Clin Oncol, 2010 May 05; 7(6). PMID: 20440284
Molecular diagnostics. At the nexus of individualized medicine, health care delivery, and public policy.
Scott A Waldman, Andre Terzic.
Clin Transl Sci, 2009 Feb 01; 2(1). PMID: 20443861    Free PMC article.
Molecular pathology and patient care.
John D Pfeifer.
Mo Med, 2010 May 08; 107(2). PMID: 20446514    Free PMC article.
Biomarkers of peripheral arterial disease.
John P Cooke, Andrew M Wilson.
J Am Coll Cardiol, 2010 May 08; 55(19). PMID: 20447524    Free PMC article.
Breast cancer diagnosis using a microfluidic multiplexed immunohistochemistry platform.
Minseok S Kim, Taemin Kim, +6 authors, Je-Kyun Park.
PLoS One, 2010 May 11; 5(5). PMID: 20454672    Free PMC article.
Protein-protein interaction reveals synergistic discrimination of cancer phenotype.
Jianghui Xiong, Juan Liu, +2 authors, Shanguang Chen.
Cancer Inform, 2010 May 12; 9. PMID: 20458363    Free PMC article.
Tamoxifen resistance in early breast cancer: statistical modelling of tissue markers to improve risk prediction.
M R Baneshi, P Warner, +3 authors, J M S Bartlett.
Br J Cancer, 2010 May 13; 102(10). PMID: 20461093    Free PMC article.
Current controversies in the management of breast cancer.
I Tusquets, L García-Estévez, +17 authors, A Lluch.
Clin Transl Oncol, 2010 May 14; 12(4). PMID: 20462837
Molecular basis for therapy resistance.
Per E Lønning.
Mol Oncol, 2010 May 15; 4(3). PMID: 20466604    Free PMC article.
PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer.
Sherene Loi, Benjamin Haibe-Kains, +17 authors, Christos Sotiriou.
Proc Natl Acad Sci U S A, 2010 May 19; 107(22). PMID: 20479250    Free PMC article.
Highly Cited.
Use of ER/PR/HER2 subtypes in conjunction with the 2007 St Gallen Consensus Statement for early breast cancer.
Katrina Bauer, Carol Parise, Vincent Caggiano.
BMC Cancer, 2010 May 25; 10. PMID: 20492696    Free PMC article.
Breast cancer adjuvant chemotherapy decisions in older women: the role of patient preference and interactions with physicians.
Jeanne S Mandelblatt, Vanessa B Sheppard, +17 authors, Cancer Leukemia Group B.
J Clin Oncol, 2010 Jun 03; 28(19). PMID: 20516438    Free PMC article.
Quantitative expression profiling in formalin-fixed paraffin-embedded samples by affymetrix microarrays.
Diana Abdueva, Michele Wing, +2 authors, Elai Davicioni.
J Mol Diagn, 2010 Jun 05; 12(4). PMID: 20522636    Free PMC article.
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer.
M Elizabeth H Hammond, Daniel F Hayes, +29 authors, Antonio C Wolff.
Arch Pathol Lab Med, 2010 Jun 09; 134(6). PMID: 20524868    Free PMC article.
Highly Cited.
Pleiotropic functions of Rho GTPase signaling: a Trojan horse or Achilles' heel for breast cancer treatment?
P R McHenry, T Vargo-Gogola.
Curr Drug Targets, 2010 Jun 16; 11(9). PMID: 20545614    Free PMC article.
Up-regulation of cell cycle arrest protein BTG2 correlates with increased overall survival in breast cancer, as detected by immunohistochemistry using tissue microarray.
Elin Möllerström, Anikó Kovács, +8 authors, Khalil Helou.
BMC Cancer, 2010 Jun 18; 10. PMID: 20553615    Free PMC article.
Cardiovascular genetic medicine: the genetics of coronary heart disease.
David Seo, Pascal J Goldschmidt-Clermont.
J Cardiovasc Transl Res, 2008 Jun 01; 1(2). PMID: 20559911
Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer.
Chad J Creighton, Xiaoyong Fu, +11 authors, Rachel Schiff.
Breast Cancer Res, 2010 Jun 24; 12(3). PMID: 20569503    Free PMC article.
Highly Cited.
Orphan nuclear receptors in breast cancer pathogenesis and therapeutic response.
Rebecca B Riggins, Mary M Mazzotta, Omar Z Maniya, Robert Clarke.
Endocr Relat Cancer, 2010 Jun 26; 17(3). PMID: 20576803    Free PMC article.
Unraveling human complexity and disease with systems biology and personalized medicine.
Stephen Naylor, Jake Y Chen.
Per Med, 2010 Jun 26; 7(3). PMID: 20577569    Free PMC article.
Integrative genomic profiling of human prostate cancer.
Barry S Taylor, Nikolaus Schultz, +23 authors, William L Gerald.
Cancer Cell, 2010 Jun 29; 18(1). PMID: 20579941    Free PMC article.
Highly Cited.
An 8-gene qRT-PCR-based gene expression score that has prognostic value in early breast cancer.
Iker Sánchez-Navarro, Angelo Gámez-Pozo, +11 authors, Enrique Espinosa.
BMC Cancer, 2010 Jun 30; 10. PMID: 20584321    Free PMC article.
A breast cancer prognostic signature predicts clinical outcomes in multiple tumor types.
Ying-Wooi Wan, Yong Qian, +2 authors, Nancy Lan Guo.
Oncol Rep, 2010 Jul 03; 24(2). PMID: 20596637    Free PMC article.
Mammostrat as a tool to stratify breast cancer patients at risk of recurrence during endocrine therapy.
John M S Bartlett, Jeremy Thomas, +12 authors, Udi Chetty.
Breast Cancer Res, 2010 Jul 10; 12(4). PMID: 20615243    Free PMC article.
American Society of Clinical Oncology clinical practice guideline: update on adjuvant endocrine therapy for women with hormone receptor-positive breast cancer.
Harold J Burstein, Ann Alexis Prestrud, +16 authors, American Society of Clinical Oncology.
J Clin Oncol, 2010 Jul 14; 28(23). PMID: 20625130    Free PMC article.
Highly Cited. Systematic Review.
Molecular therapy of breast cancer: progress and future directions.
Sheng-Xiang Lin, Jiong Chen, +4 authors, Ming Zhou.
Nat Rev Endocrinol, 2010 Jul 21; 6(9). PMID: 20644568
Technology as a force for improved diagnosis and treatment of breast disease.
Claire M B Holloway, Alexandra Easson, +5 authors, David R McCready.
Can J Surg, 2010 Jul 22; 53(4). PMID: 20646402    Free PMC article.
Predictive relevance of HOXB13 protein expression for tamoxifen benefit in breast cancer.
Piiha-Lotta Jerevall, Agneta Jansson, +3 authors, Olle Stål.
Breast Cancer Res, 2010 Jul 24; 12(4). PMID: 20649975    Free PMC article.
BCL2 in breast cancer: a favourable prognostic marker across molecular subtypes and independent of adjuvant therapy received.
S-J Dawson, N Makretsov, +17 authors, P Pharoah.
Br J Cancer, 2010 Jul 29; 103(5). PMID: 20664598    Free PMC article.
Highly Cited.
Relationship between tumor gene expression and recurrence in four independent studies of patients with stage II/III colon cancer treated with surgery alone or surgery plus adjuvant fluorouracil plus leucovorin.
Michael J O'Connell, Ian Lavery, +9 authors, Norman Wolmark.
J Clin Oncol, 2010 Aug 04; 28(25). PMID: 20679606    Free PMC article.
Highly Cited.
Ferroportin and iron regulation in breast cancer progression and prognosis.
Zandra K Pinnix, Lance D Miller, +9 authors, Frank M Torti.
Sci Transl Med, 2010 Aug 06; 2(43). PMID: 20686179    Free PMC article.
Highly Cited.
The Expression Patterns of ER, PR, HER2, CK5/6, EGFR, Ki-67 and AR by Immunohistochemical Analysis in Breast Cancer Cell Lines.
Kristina Subik, Jin-Feng Lee, +8 authors, Ping Tang.
Breast Cancer (Auckl), 2010 Aug 11; 4. PMID: 20697531    Free PMC article.
Highly Cited.
Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool.
Y H Chia, M J Ellis, C X Ma.
Br J Cancer, 2010 Aug 12; 103(6). PMID: 20700118    Free PMC article.
Molecular apocrine differentiation is a common feature of breast cancer in patients with germline PTEN mutations.
Guillaume Banneau, Mickaël Guedj, +15 authors, Michel Longy.
Breast Cancer Res, 2010 Aug 18; 12(4). PMID: 20712882    Free PMC article.
Antibody-based proteomics: fast-tracking molecular diagnostics in oncology.
Donal J Brennan, Darran P O'Connor, +2 authors, William M Gallagher.
Nat Rev Cancer, 2010 Aug 20; 10(9). PMID: 20720569
Enumerating the gene sets in breast cancer, a "direct" alternative to hierarchical clustering.
Dwain Mefford, Joel A Mefford.
BMC Genomics, 2010 Aug 25; 11. PMID: 20731868    Free PMC article.
Microarray data analysis in neoadjuvant biomarker studies in estrogen receptor-positive breast cancer.
Jingqin Luo, Matthew J Ellis.
Breast Cancer Res, 2010 Sep 02; 12(4). PMID: 20804563    Free PMC article.
Breast cancer prognostic classification in the molecular era: the role of histological grade.
Emad A Rakha, Jorge S Reis-Filho, +15 authors, Ian O Ellis.
Breast Cancer Res, 2010 Sep 02; 12(4). PMID: 20804570    Free PMC article.
Highly Cited. Review.
Hybrid models identified a 12-gene signature for lung cancer prognosis and chemoresponse prediction.
Ying-Wooi Wan, Ebrahim Sabbagh, +6 authors, Nancy Lan Guo.
PLoS One, 2010 Sep 03; 5(8). PMID: 20808922    Free PMC article.
Gene-expression profiling in breast cancer: bespoke cancer therapy or more fiction than science?
M Barry, M R Kell.
Ir J Med Sci, 2010 Sep 03; 179(4). PMID: 20809382
Benefits of biomarker selection and clinico-pathological covariate inclusion in breast cancer prognostic models.
Fabio Parisi, Ana M Gonzalez, +4 authors, Yuval Kluger.
Breast Cancer Res, 2010 Sep 03; 12(5). PMID: 20809974    Free PMC article.
Minimizing early relapse and maximizing treatment outcomes in hormone-sensitive postmenopausal breast cancer: efficacy review of AI trials.
Christos J Markopoulos.
Cancer Metastasis Rev, 2010 Sep 11; 29(4). PMID: 20830503    Free PMC article.
A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptor-positive breast cancer.
Torsten O Nielsen, Joel S Parker, +12 authors, Matthew J Ellis.
Clin Cancer Res, 2010 Sep 15; 16(21). PMID: 20837693    Free PMC article.
Highly Cited.
Targeted Therapy in Breast Cancer.
Andreas Schneeweiss.
Breast Care (Basel), 2010 Sep 18; 5(3). PMID: 20847825    Free PMC article.
Impact of a commercial reference laboratory test recurrence score on decision making in early-stage breast cancer.
Ruth Oratz, Dev Paul, Allen L Cohn, Scot M Sedlacek.
J Oncol Pract, 2007 Jul 01; 3(4). PMID: 20859407    Free PMC article.
Editorial: gene expression profile assays as an aid in treatment decision making in early-stage breast cancer.
Gary H Lyman.
J Oncol Pract, 2007 Jul 01; 3(4). PMID: 20859408    Free PMC article.
Survivin is not induced by novel taxanes.
Nima Sharifi, Jun Qi, +6 authors, David G I Kingston.
Mol Pharm, 2010 Sep 25; 7(6). PMID: 20863081    Free PMC article.
Molecular Stratification of Clear Cell Renal Cell Carcinoma by Consensus Clustering Reveals Distinct Subtypes and Survival Patterns.
A Rose Brannon, Anupama Reddy, +13 authors, W Kimryn Rathmell.
Genes Cancer, 2010 Sep 28; 1(2). PMID: 20871783    Free PMC article.
Highly Cited.
DNA repair and personalized breast cancer therapy.
Shu-Xia Li, Ashley Sjolund, Lyndsay Harris, Joann B Sweasy.
Environ Mol Mutagen, 2010 Sep 28; 51(8-9). PMID: 20872853    Free PMC article.
Modulation of plasma complement by the initial dose of epirubicin/docetaxel therapy in breast cancer and its predictive value.
A Michlmayr, T Bachleitner-Hofmann, +12 authors, R Oehler.
Br J Cancer, 2010 Sep 30; 103(8). PMID: 20877360    Free PMC article.
Tumor gene expression profiling in women with breast cancer. Test category: prognostic.
Cecelia Bellcross, W David Dotson.
PLoS Curr, 2010 Sep 30; 2. PMID: 20877449    Free PMC article.
Mechanisms of endocrine resistance in breast cancer.
C Kent Osborne, Rachel Schiff.
Annu Rev Med, 2010 Oct 05; 62. PMID: 20887199    Free PMC article.
Highly Cited. Review.
Maximum growth and survival of estrogen receptor-alpha positive breast cancer cells requires the Sin3A transcriptional repressor.
Stephanie J Ellison-Zelski, Elaine T Alarid.
Mol Cancer, 2010 Oct 06; 9. PMID: 20920219    Free PMC article.
A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer.
Christina Yau, Laura Esserman, +3 authors, Christopher C Benz.
Breast Cancer Res, 2010 Oct 16; 12(5). PMID: 20946665    Free PMC article.
Genomic collaboration of estrogen receptor alpha and extracellular signal-regulated kinase 2 in regulating gene and proliferation programs.
Zeynep Madak-Erdogan, Mathieu Lupien, +2 authors, Benita S Katzenellenbogen.
Mol Cell Biol, 2010 Oct 20; 31(1). PMID: 20956553    Free PMC article.
Synthetic lethal approaches to breast cancer therapy.
Farah L Rehman, Christopher J Lord, Alan Ashworth.
Nat Rev Clin Oncol, 2010 Oct 20; 7(12). PMID: 20956981
Identification of high-quality cancer prognostic markers and metastasis network modules.
Jie Li, Anne E G Lenferink, +5 authors, Edwin Wang.
Nat Commun, 2010 Oct 27; 1. PMID: 20975711    Free PMC article.
Highly Cited.
Breast cancer assessment tools and optimizing adjuvant therapy.
Catherine Oakman, Libero Santarpia, Angelo Di Leo.
Nat Rev Clin Oncol, 2010 Oct 27; 7(12). PMID: 20975745
Breast cancer in the personal genomics era.
Rachel E Ellsworth, David J Decewicz, Craig D Shriver, Darrell L Ellsworth.
Curr Genomics, 2010 Nov 03; 11(3). PMID: 21037853    Free PMC article.
Systems biology and genomics of breast cancer.
Charles M Perou, Anne-Lise Børresen-Dale.
Cold Spring Harb Perspect Biol, 2010 Nov 05; 3(2). PMID: 21047916    Free PMC article.
Adjuvant Systemic Therapy, Quo Vadis? Patient Selection, Prognostic and Predictive Factors.
Fatima Cardoso.
Breast Care (Basel), 2008 Jan 01; 3(6). PMID: 21048908    Free PMC article.
Multi-level reproducibility of signature hubs in human interactome for breast cancer metastasis.
Chen Yao, Hongdong Li, +3 authors, Zheng Guo.
BMC Syst Biol, 2010 Nov 10; 4. PMID: 21059271    Free PMC article.
The UCSC Cancer Genomics Browser: update 2011.
J Zachary Sanborn, Stephen C Benz, +12 authors, Jingchun Zhu.
Nucleic Acids Res, 2010 Nov 10; 39(Database issue). PMID: 21059681    Free PMC article.
Conversion of a molecular classifier obtained by gene expression profiling into a classifier based on real-time PCR: a prognosis predictor for gliomas.
Satoru Kawarazaki, Kazuya Taniguchi, +7 authors, Kikuya Kato.
BMC Med Genomics, 2010 Nov 11; 3. PMID: 21062501    Free PMC article.
Chemoendocrine Treatment Is Standard in Hormone Receptor-Positive Patients.
Volkmar Müller.
Breast Care (Basel), 2008 Jan 01; 3(4). PMID: 21076601    Free PMC article.
Is Chemoendocrine Treatment without Alternative?
Richard Greil.
Breast Care (Basel), 2008 Jan 01; 3(4). PMID: 21076602    Free PMC article.
Node-Negative Breast Cancer: Which Patients Should Be Treated?
Marcus Schmidt.
Breast Care (Basel), 2008 Jan 01; 3(4). PMID: 21076603    Free PMC article.
Identification of a low-risk subgroup of HER-2-positive breast cancer by the 70-gene prognosis signature.
M Knauer, F Cardoso, +4 authors, L J van 't Veer.
Br J Cancer, 2010 Nov 18; 103(12). PMID: 21081926    Free PMC article.
Tumor profiling: development of prognostic and predictive factors to guide brain tumor treatment.
Stephen H Settle, Erik P Sulman.
Curr Oncol Rep, 2010 Nov 18; 13(1). PMID: 21082294
Prostate cancer genomic signature offers prognostic value.
Sarah M Troutman, Douglas K Price, William D Figg.
Cancer biology & therapy, 2010 Nov 20; 10(11). PMID: 21088497    Free PMC article.
Predicting prognosis of breast cancer with gene signatures: are we lost in a sea of data?
Takayuki Iwamoto, Lajos Pusztai.
Genome Med, 2010 Nov 26; 2(11). PMID: 21092148    Free PMC article.
Validation of cytoplasmic-to-nuclear ratio of survivin as an indicator of improved prognosis in breast cancer.
Elton Rexhepaj, Karin Jirstrom, +5 authors, William M Gallagher.
BMC Cancer, 2010 Nov 26; 10. PMID: 21092276    Free PMC article.
Evaluation of external RNA controls for the standardisation of gene expression biomarker measurements.
Alison S Devonshire, Ramnath Elaswarapu, Carole A Foy.
BMC Genomics, 2010 Nov 26; 11. PMID: 21106083    Free PMC article.
In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome.
Simen Myhre, Hayat Mohammed, +7 authors, Therese Sørlie.
PLoS One, 2010 Dec 03; 5(11). PMID: 21124964    Free PMC article.
The molecular pathology of breast cancer progression.
Alessandro Bombonati, Dennis C Sgroi.
J Pathol, 2010 Dec 03; 223(2). PMID: 21125683    Free PMC article.
Prognostic gene network modules in breast cancer hold promise.
Andrew E Teschendorff, Yan Jiao, Carlos Caldas.
Breast Cancer Res, 2010 Dec 15; 12(6). PMID: 21143771    Free PMC article.
Deconstructing the molecular portraits of breast cancer.
Aleix Prat, Charles M Perou.
Mol Oncol, 2010 Dec 15; 5(1). PMID: 21147047    Free PMC article.
Highly Cited. Review.
Moving forward in human cancer risk assessment.
Richard S Paules, Jiri Aubrecht, +2 authors, Jos C Kleinjans.
Environ Health Perspect, 2010 Dec 15; 119(6). PMID: 21147607    Free PMC article.
Should Histologic Grade Be Incorporated into the TNM Classification System for Small (T1, T2) Node-Negative Breast Adenocarcinomas?
Mathew Purdom, Michael L Cibull, +4 authors, Rouzan G Karabakhtsian.
Patholog Res Int, 2010 Dec 15; 2011. PMID: 21151541    Free PMC article.
Invasive Lobular Carcinomas Do Not Express Basal Cytokeratin Markers CK5/6, CK14 and CK17.
Natalya Khilko, Jianmin Wang, +2 authors, Ping Tang.
Breast Cancer (Auckl), 2010 Dec 15; 4. PMID: 21151863    Free PMC article.
Minimising immunohistochemical false negative ER classification using a complementary 23 gene expression signature of ER status.
Qiyuan Li, Aron C Eklund, +5 authors, Charles Swanton.
PLoS One, 2010 Dec 15; 5(12). PMID: 21152022    Free PMC article.
A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients.
Stephanie Roessler, Hu-Liang Jia, +8 authors, Xin Wei Wang.
Cancer Res, 2010 Dec 17; 70(24). PMID: 21159642    Free PMC article.
Highly Cited.
A 12-gene genomic instability signature predicts clinical outcomes in multiple cancer types.
Rama K R Mettu, Ying-Wooi Wan, +2 authors, Nancy Lan Guo.
Int J Biol Markers, 2010 Dec 17; 25(4). PMID: 21161944    Free PMC article.
A multiplex endpoint RT-PCR assay for quality assessment of RNA extracted from formalin-fixed paraffin-embedded tissues.
Elena A Takano, Thomas Mikeska, +2 authors, Stephen B Fox.
BMC Biotechnol, 2010 Dec 18; 10. PMID: 21162754    Free PMC article.
A five-gene and corresponding protein signature for stage-I lung adenocarcinoma prognosis.
Humam Kadara, Carmen Behrens, +9 authors, Reuben Lotan.
Clin Cancer Res, 2010 Dec 18; 17(6). PMID: 21163870    Free PMC article.
TSPYL5 suppresses p53 levels and function by physical interaction with USP7.
Mirjam T Epping, Lars A T Meijer, +3 authors, René Bernards.
Nat Cell Biol, 2010 Dec 21; 13(1). PMID: 21170034
Expression profiling of formalin-fixed paraffin-embedded primary breast tumors using cancer-specific and whole genome gene panels on the DASL® platform.
Monica M Reinholz, Jeanette E Eckel-Passow, +14 authors, Wilma L Lingle.
BMC Med Genomics, 2010 Dec 22; 3. PMID: 21172013    Free PMC article.
Are current development programs realising the full potential of new agents?
Per Eystein Lønning.
Breast Cancer Res, 2011 Jan 05; 12 Suppl 4. PMID: 21172086    Free PMC article.
Systems pathology.
Dana Faratian.
Breast Cancer Res, 2011 Jan 05; 12 Suppl 4. PMID: 21172088    Free PMC article.
Molecular profiling currently offers no more than tumour morphology and basic immunohistochemistry.
Britta Weigelt, Jorge S Reis-Filho.
Breast Cancer Res, 2011 Jan 05; 12 Suppl 4. PMID: 21172089    Free PMC article.
Translating tumor biology into personalized treatment planning: analytical performance characteristics of the Oncotype DX Colon Cancer Assay.
Kim M Clark-Langone, Chithra Sangli, Jayadevi Krishnakumar, Drew Watson.
BMC Cancer, 2010 Dec 24; 10. PMID: 21176237    Free PMC article.
Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia.
Andrew J Gentles, Sylvia K Plevritis, Ravindra Majeti, Ash A Alizadeh.
JAMA, 2010 Dec 24; 304(24). PMID: 21177505    Free PMC article.
Highly Cited.
Coverage policy development for personalized medicine: private payer perspectives on developing policy for the 21-gene assay.
Julia R Trosman, Stephanie L Van Bebber, Kathryn A Phillips.
J Oncol Pract, 2011 Jan 05; 6(5). PMID: 21197187    Free PMC article.
Classification of ipsilateral breast tumor recurrences after breast conservation therapy can predict patient prognosis and facilitate treatment planning.
Min Yi, Thomas A Buchholz, +12 authors, Kelly K Hunt.
Ann Surg, 2011 Jan 07; 253(3). PMID: 21209588    Free PMC article.
The tumor microenvironment in colorectal carcinogenesis.
Vijay G Peddareddigari, Dingzhi Wang, Raymond N Dubois.
Cancer Microenviron, 2011 Jan 07; 3(1). PMID: 21209781    Free PMC article.
Postoperative fever: the potential relationship with prognosis in node negative breast cancer patients.
Tingting Yan, Wenjin Yin, +4 authors, Jinsong Lu.
PLoS One, 2011 Jan 07; 5(12). PMID: 21209958    Free PMC article.
Building prognostic models for breast cancer patients using clinical variables and hundreds of gene expression signatures.
Cheng Fan, Aleix Prat, +4 authors, Charles M Perou.
BMC Med Genomics, 2011 Jan 11; 4. PMID: 21214954    Free PMC article.
Risk of a second breast cancer associated with hormone-receptor and HER2/neu status of the first breast cancer.
Leona Bessonova, Thomas H Taylor, +2 authors, Hoda Anton-Culver.
Cancer Epidemiol Biomarkers Prev, 2011 Jan 11; 20(2). PMID: 21217087    Free PMC article.
Comparison of the prognostic and predictive utilities of the 21-gene Recurrence Score assay and Adjuvant! for women with node-negative, ER-positive breast cancer: results from NSABP B-14 and NSABP B-20.
Gong Tang, Steven Shak, +6 authors, Norman Wolmark.
Breast Cancer Res Treat, 2011 Jan 12; 127(1). PMID: 21221771    Free PMC article.
Young age, increased tumor proliferation and FOXM1 expression predict early metastatic relapse only for endocrine-dependent breast cancers.
Christina Yau, Yixin Wang, +2 authors, Christopher C Benz.
Breast Cancer Res Treat, 2011 Jan 13; 126(3). PMID: 21225456    Free PMC article.
High-throughput ectopic expression screen for tamoxifen resistance identifies an atypical kinase that blocks autophagy.
Laura Gonzalez-Malerva, Jaehong Park, +7 authors, Joshua LaBaer.
Proc Natl Acad Sci U S A, 2011 Jan 15; 108(5). PMID: 21233418    Free PMC article.
Meningeal carcinomatosis in breast cancer: prognostic factors and outcome.
Carla Rameri Alexandre Silva de Azevedo, Marcelo Rocha Sousa Cruz, +5 authors, Daniel Luiz Gimenes.
J Neurooncol, 2011 Jan 15; 104(2). PMID: 21234642
Incorporating fertility preservation into the care of young oncology patients.
Amanda J Redig, Robert Brannigan, +2 authors, Jacqueline S Jeruss.
Cancer, 2011 Jan 15; 117(1). PMID: 21235031    Free PMC article.
A 20-gene model for molecular nodal staging of bladder cancer: development and prospective assessment.
Steven Christopher Smith, Alexander Spyridon Baras, +9 authors, Dan Theodorescu.
Lancet Oncol, 2011 Jan 25; 12(2). PMID: 21256081    Free PMC article.
Confident predictability: identifying reliable gene expression patterns for individualized tumor classification using a local minimax kernel algorithm.
Lee K Jones, Fei Zou, +3 authors, Aik Choon Tan.
BMC Med Genomics, 2011 Jan 26; 4. PMID: 21261972    Free PMC article.
Breast cancer and fertility preservation.
S Samuel Kim, Jennifer Klemp, Carol Fabian.
Fertil Steril, 2011 Jan 29; 95(5). PMID: 21272867    Free PMC article.
Physical and psychosocial recovery in the year after primary treatment of breast cancer.
Patricia A Ganz, Lorna Kwan, +2 authors, Thomas R Belin.
J Clin Oncol, 2011 Feb 09; 29(9). PMID: 21300931    Free PMC article.
Diabetes and biomarkers.
Erica J Caveney, Oren J Cohen.
J Diabetes Sci Technol, 2011 Feb 10; 5(1). PMID: 21303644    Free PMC article.
Charting a course for genomic medicine from base pairs to bedside.
Eric D Green, Mark S Guyer, National Human Genome Research Institute.
Nature, 2011 Feb 11; 470(7333). PMID: 21307933
Highly Cited.
A four-gene signature predicts disease progression in muscle invasive bladder cancer.
Wun-Jae Kim, Seon-Kyu Kim, +6 authors, Yung Hyun Choi.
Mol Med, 2011 Feb 11; 17(5-6). PMID: 21308147    Free PMC article.
Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study.
Jack Cuzick, Gregory P Swanson, +18 authors, Transatlantic Prostate Group.
Lancet Oncol, 2011 Feb 12; 12(3). PMID: 21310658    Free PMC article.
Highly Cited.
Par genes: molecular probes to pathological assessment in breast cancer progression.
Beatrice Uziely, Hagit Turm, +3 authors, Rachel Bar-Shavit.
Patholog Res Int, 2011 Feb 15; 2011. PMID: 21318117    Free PMC article.
Small-molecule protein kinase inhibitors and their effects on the immune system: implications for cancer treatment.
Patrick A Ott, Sylvia Adams.
Immunotherapy, 2011 Feb 17; 3(2). PMID: 21322760    Free PMC article.
Challenges to developing proteomic-based breast cancer diagnostics.
Richard R Drake, Lisa H Cazares, +3 authors, Christine Laronga.
OMICS, 2011 Feb 22; 15(5). PMID: 21332380    Free PMC article.
Gene signatures of breast cancer progression and metastasis.
David I Rodenhiser, Joseph D Andrews, Theodore A Vandenberg, Ann F Chambers.
Breast Cancer Res, 2011 Feb 25; 13(1). PMID: 21345283    Free PMC article.
Gene List significance at-a-glance with GeneValorization.
Bryan Brancotte, Anne Biton, +3 authors, Sarah Cohen-Boulakia.
Bioinformatics, 2011 Feb 26; 27(8). PMID: 21349868    Free PMC article.
Can some patients avoid adjuvant chemotherapy for early-stage breast cancer?
Philippe L Bedard, Fatima Cardoso.
Nat Rev Clin Oncol, 2011 Mar 03; 8(5). PMID: 21364525
Methodological and practical challenges for personalized cancer therapies.
Ignacio I Wistuba, Juri G Gelovani, +2 authors, Roy S Herbst.
Nat Rev Clin Oncol, 2011 Mar 03; 8(3). PMID: 21364686
Taming the dragon: genomic biomarkers to individualize the treatment of cancer.
Ian J Majewski, René Bernards.
Nat Med, 2011 Mar 10; 17(3). PMID: 21386834
Pro-oncogene Pokemon promotes breast cancer progression by upregulating survivin expression.
Xuyu Zu, Jun Ma, +7 authors, Yuyang Jiang.
Breast Cancer Res, 2011 Mar 12; 13(2). PMID: 21392388    Free PMC article.
Making sense of cancer genomic data.
Lynda Chin, William C Hahn, Gad Getz, Matthew Meyerson.
Genes Dev, 2011 Mar 17; 25(6). PMID: 21406553    Free PMC article.
Highly Cited. Review.
Exon-array profiling unlocks clinically and biologically relevant gene signatures from formalin-fixed paraffin-embedded tumour samples.
J S Hall, H S Leong, +8 authors, C M L West.
Br J Cancer, 2011 Mar 17; 104(6). PMID: 21407225    Free PMC article.
Microarray-based class discovery for molecular classification of breast cancer: analysis of interobserver agreement.
Alan Mackay, Britta Weigelt, +7 authors, Jorge S Reis-Filho.
J Natl Cancer Inst, 2011 Mar 23; 103(8). PMID: 21421860    Free PMC article.
Do two machine-learning based prognostic signatures for breast cancer capture the same biological processes?
Yotam Drier, Eytan Domany.
PLoS One, 2011 Mar 23; 6(3). PMID: 21423753    Free PMC article.
Combining gene signatures improves prediction of breast cancer survival.
Xi Zhao, Einar Andreas Rødland, +6 authors, Ole Christian Lingjærde.
PLoS One, 2011 Mar 23; 6(3). PMID: 21423775    Free PMC article.
Breast cancer methylomes establish an epigenomic foundation for metastasis.
Fang Fang, Sevin Turcan, +15 authors, Timothy A Chan.
Sci Transl Med, 2011 Mar 25; 3(75). PMID: 21430268    Free PMC article.
Highly Cited.
Prognostic significance of TRIM24/TIF-1α gene expression in breast cancer.
Monique Chambon, Béatrice Orsetti, +8 authors, Vincent Cavaillès.
Am J Pathol, 2011 Mar 26; 178(4). PMID: 21435435    Free PMC article.
Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients.
Michael R Elashoff, James A Wingrove, +13 authors, Eric J Topol.
BMC Med Genomics, 2011 Mar 30; 4. PMID: 21443790    Free PMC article.
GOBO: gene expression-based outcome for breast cancer online.
Markus Ringnér, Erik Fredlund, +2 authors, Johan Staaf.
PLoS One, 2011 Mar 30; 6(3). PMID: 21445301    Free PMC article.
Highly Cited.
Gene expression signature-based prognostic risk score in gastric cancer.
Jae Yong Cho, Jae Yun Lim, +13 authors, Ju-Seog Lee.
Clin Cancer Res, 2011 Mar 31; 17(7). PMID: 21447720    Free PMC article.
Highly Cited.
E2F1 and KIAA0191 expression predicts breast cancer patient survival.
Robin M Hallett, John A Hassell.
BMC Res Notes, 2011 Apr 02; 4. PMID: 21453498    Free PMC article.
Biomarker discovery using statistically significant gene sets.
Hoon Kim, John Watkinson, Dimitris Anastassiou.
J Comput Biol, 2011 Apr 05; 18(10). PMID: 21457009    Free PMC article.
Design and multiseries validation of a web-based gene expression assay for predicting breast cancer recurrence and patient survival.
Ryan K Van Laar.
J Mol Diagn, 2011 Apr 05; 13(3). PMID: 21458382    Free PMC article.
Mass spectrometric characterization of protein structure details refines the proteome signature for invasive ductal breast carcinoma.
Claudia Röwer, Cornelia Koy, +4 authors, Michael O Glocker.
J Am Soc Mass Spectrom, 2011 Apr 08; 22(3). PMID: 21472563
miRNA Biomarkers in Breast Cancer Detection and Management.
Sidney W Fu, Liang Chen, Yan-Gao Man.
J Cancer, 2011 Apr 12; 2. PMID: 21479130    Free PMC article.
Examining the influence of beta blockers and ACE inhibitors on the risk for breast cancer recurrence: results from the LACE cohort.
Patricia A Ganz, Laurel A Habel, +2 authors, Steven W Cole.
Breast Cancer Res Treat, 2011 Apr 12; 129(2). PMID: 21479924    Free PMC article.
Prospective evaluation of prognostic factors uPA/PAI-1 in node-negative breast cancer: phase III NNBC3-Europe trial (AGO, GBG, EORTC-PBG) comparing 6×FEC versus 3×FEC/3×Docetaxel.
Eva J Kantelhardt, Martina Vetter, +12 authors, Nadia Harbeck.
BMC Cancer, 2011 Apr 19; 11. PMID: 21496284    Free PMC article.
Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization.
Kuo-Jang Kao, Kai-Ming Chang, Hui-Chi Hsu, Andrew T Huang.
BMC Cancer, 2011 Apr 20; 11. PMID: 21501481    Free PMC article.
Highly Cited.
Preclinical strategies to define predictive biomarkers for therapeutically relevant cancer subtypes.
Marina Pajic, Christopher J Scarlett, +2 authors, Andrew V Biankin.
Hum Genet, 2011 Apr 26; 130(1). PMID: 21516344
Metastasis-suppressor genes in clinical practice: lost in translation?
Alexander N Shoushtari, Russell Z Szmulewitz, Carrie W Rinker-Schaeffer.
Nat Rev Clin Oncol, 2011 Apr 28; 8(6). PMID: 21522123
Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications.
Taru A Muranen, Dario Greco, +7 authors, Heli Nevanlinna.
Breast Cancer Res, 2011 May 06; 13(5). PMID: 21542898    Free PMC article.
mRNA transcript quantification in archival samples using multiplexed, color-coded probes.
Patricia P Reis, Levi Waldron, +7 authors, Suzanne Kamel-Reid.
BMC Biotechnol, 2011 May 10; 11. PMID: 21549012    Free PMC article.
Highly Cited.
Tamoxifen in early-stage estrogen receptor-positive breast cancer: overview of clinical use and molecular biomarkers for patient selection.
Carmen Criscitiello, Debora Fumagalli, Kamal S Saini, Sherene Loi.
Onco Targets Ther, 2011 May 10; 4. PMID: 21552410    Free PMC article.
Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based intrinsic subtype--ACOSOG Z1031.
Matthew J Ellis, Vera J Suman, +17 authors, John A Olson.
J Clin Oncol, 2011 May 11; 29(17). PMID: 21555689    Free PMC article.
Highly Cited.
Breast cancer adjuvant therapy: time to consider its time-dependent effects.
Ismail Jatoi, William F Anderson, Jong-Hyeon Jeong, Carol K Redmond.
J Clin Oncol, 2011 May 11; 29(17). PMID: 21555693    Free PMC article.
Prognostic utility of HOXB13:IL17BR and molecular grade index in early-stage breast cancer patients from the Stockholm trial.
P-L Jerevall, X-J Ma, +9 authors, O Stål.
Br J Cancer, 2011 May 12; 104(11). PMID: 21559019    Free PMC article.
A multimarker QPCR-based platform for the detection of circulating tumour cells in patients with early-stage breast cancer.
T J Molloy, L A Devriese, +5 authors, L J van't Veer.
Br J Cancer, 2011 May 19; 104(12). PMID: 21587256    Free PMC article.
Biologic markers determine both the risk and the timing of recurrence in breast cancer.
Laura J Esserman, Dan H Moore, +11 authors, Christopher C Benz.
Breast Cancer Res Treat, 2011 May 21; 129(2). PMID: 21597921    Free PMC article.
Combining urinary detection of TMPRSS2:ERG and PCA3 with serum PSA to predict diagnosis of prostate cancer.
Simpa S Salami, Folke Schmidt, +10 authors, Martin G Sanda.
Urol Oncol, 2011 May 24; 31(5). PMID: 21600800    Free PMC article.
Innovations in chemotherapy and radiation therapy: Implications and opportunities for the Asia-Pacific Rim.
D E Heron, J E Shogan, J W Mucenski.
Biomed Imaging Interv J, 2008 Jul 01; 4(3). PMID: 21611006    Free PMC article.
A tri-marker proliferation index predicts biochemical recurrence after surgery for prostate cancer.
Sameer Malhotra, Jacques Lapointe, +6 authors, Jonathan R Pollack.
PLoS One, 2011 Jun 02; 6(5). PMID: 21629784    Free PMC article.
Adjuvant chemotherapy for breast cancer in older women: emerging evidence to aid in decision making.
Gretchen Kimmick.
Curr Treat Options Oncol, 2011 Jun 04; 12(3). PMID: 21638199
A methyl-deviator epigenotype of estrogen receptor-positive breast carcinoma is associated with malignant biology.
J Keith Killian, Sven Bilke, +8 authors, Paul S Meltzer.
Am J Pathol, 2011 Jun 07; 179(1). PMID: 21641572    Free PMC article.
Protein expression based multimarker analysis of breast cancer samples.
Angela P Presson, Nam K Yoon, +7 authors, Steve Horvath.
BMC Cancer, 2011 Jun 10; 11. PMID: 21651811    Free PMC article.
Domain and functional analysis of a novel breast tumor suppressor protein, SCUBE2.
Yuh-Charn Lin, Chun-Chuan Chen, Chien-Jui Cheng, Ruey-Bing Yang.
J Biol Chem, 2011 Jun 10; 286(30). PMID: 21652720    Free PMC article.
Emerging tactical strategies for fighting the war on cancer based on the genetic landscape.
Peter D Burbelo, Kathryn H Ching, Kathleen E Bren, Michael J Iadarola.
Am J Transl Res, 2011 Jun 10; 3(3). PMID: 21654880    Free PMC article.
Right-side and left-side colon cancer follow different pathways to relapse.
Kerry M Bauer, Amanda B Hummon, Steven Buechler.
Mol Carcinog, 2011 Jun 10; 51(5). PMID: 21656576    Free PMC article.
Global profiling of signaling networks: study of breast cancer stem cells and potential regulation.
Hongxia Wang, Mingzhu Huang, David Y Zhang, Fengchun Zhang.
Oncologist, 2011 Jun 15; 16(7). PMID: 21665913    Free PMC article.
The changing role of pathology in breast cancer diagnosis and treatment.
Anthony S-Y Leong, Zhengping Zhuang.
Pathobiology, 2011 Jun 17; 78(2). PMID: 21677473    Free PMC article.
Clinical relevance of DNA microarray analyses using archival formalin-fixed paraffin-embedded breast cancer specimens.
Al Muktafi Sadi, Dong-Yu Wang, +4 authors, Wey L Leong.
BMC Cancer, 2011 Jun 18; 11. PMID: 21679412    Free PMC article.
Gene expression profile testing for breast cancer and the use of chemotherapy, serious adverse effects, and costs of care.
Jennifer S Haas, Su-Ying Liang, +3 authors, Kathryn A Phillips.
Breast Cancer Res Treat, 2011 Jun 18; 130(2). PMID: 21681446    Free PMC article.
A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers.
Bryan T Hennessy, Yiling Lu, +18 authors, Gordon B Mills.
Clin Proteomics, 2011 Jun 22; 6(4). PMID: 21691416    Free PMC article.
Highly Cited.
Gene expression analysis characterizes antemortem stress and has implications for establishing cause of death.
David Jardine, Leanne Cornel, Mary Emond.
Physiol Genomics, 2011 Jun 23; 43(16). PMID: 21693618    Free PMC article.
TFRC and ACTB as the best reference genes to quantify Urokinase Plasminogen Activator in breast cancer.
Keivan Majidzadeh-A, Rezvan Esmaeili, Nasrin Abdoli.
BMC Res Notes, 2011 Jun 28; 4. PMID: 21702980    Free PMC article.
Prediction of outcome of early ER+ breast cancer is improved using a biomarker panel, which includes Ki-67 and p53.
E K A Millar, P H Graham, +10 authors, R L Sutherland.
Br J Cancer, 2011 Jun 30; 105(2). PMID: 21712826    Free PMC article.
Systematic bias in genomic classification due to contaminating non-neoplastic tissue in breast tumor samples.
Fathi Elloumi, Zhiyuan Hu, +4 authors, Melissa A Troester.
BMC Med Genomics, 2011 Jul 02; 4. PMID: 21718502    Free PMC article.
Physician survey of the effect of the 21-gene recurrence score assay results on treatment recommendations for patients with lymph node-positive, estrogen receptor-positive breast cancer.
Ruth Oratz, Benjamin Kim, +4 authors, Michael Broder.
J Oncol Pract, 2011 Jul 07; 7(2). PMID: 21731516    Free PMC article.
Global microRNA expression profiling identifies MiR-210 associated with tumor proliferation, invasion and poor clinical outcome in breast cancer.
Françoise Rothé, Michail Ignatiadis, +9 authors, Christos Sotiriou.
PLoS One, 2011 Jul 09; 6(6). PMID: 21738599    Free PMC article.
Highly Cited.
Proinvasion metastasis drivers in early-stage melanoma are oncogenes.
Kenneth L Scott, Cristina Nogueira, +19 authors, Lynda Chin.
Cancer Cell, 2011 Jul 12; 20(1). PMID: 21741599    Free PMC article.
Genomic biomarkers in predictive medicine: an interim analysis.
Richard Simon.
EMBO Mol Med, 2011 Jul 12; 3(8). PMID: 21744497    Free PMC article.
Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737.
Samantha R Oakes, François Vaillant, +14 authors, Geoffrey J Lindeman.
Proc Natl Acad Sci U S A, 2011 Jul 20; 109(8). PMID: 21768359    Free PMC article.
Differentially expressed genes in window trials are influenced by the wound-healing process: lessons learned from a pilot study with anastrozole.
Mary Morrogh, Victor P Andrade, +7 authors, Tari A King.
J Surg Res, 2011 Jul 23; 176(1). PMID: 21777924    Free PMC article.
Prognostic and Predictive Markers for Treatment Decisions in Early Breast Cancer.
Elmar Stickeler.
Breast Care (Basel), 2011 Jul 23; 6(3). PMID: 21779224    Free PMC article.
Identification of the YES1 Kinase as a Therapeutic Target in Basal-Like Breast Cancers.
Erhan Bilal, Gabriela Alexe, +6 authors, Gyan Bhanot.
Genes Cancer, 2011 Jul 23; 1(10). PMID: 21779430    Free PMC article.
Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction.
Pierre-Emmanuel Colombo, Fernanda Milanezi, Britta Weigelt, Jorge S Reis-Filho.
Breast Cancer Res, 2011 Jul 27; 13(3). PMID: 21787441    Free PMC article.
Predictive and prognostic molecular markers for cancer medicine.
Sunali Mehta, Andrew Shelling, +4 authors, Cristin Print.
Ther Adv Med Oncol, 2010 Mar 01; 2(2). PMID: 21789130    Free PMC article.
Innate immune cells in breast cancer--from villains to heroes?
Tim Kees, Mikala Egeblad.
J Mammary Gland Biol Neoplasia, 2011 Jul 27; 16(3). PMID: 21789554
Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response.
Qiyuan Li, Aron C Eklund, +8 authors, Zoltan Szallasi.
BMC Bioinformatics, 2011 Jul 30; 12. PMID: 21798043    Free PMC article.
Challenges in the management of stage II colon cancer.
Efrat Dotan, Steven J Cohen.
Semin Oncol, 2011 Aug 04; 38(4). PMID: 21810510    Free PMC article.
SEOM clinical guidelines for using molecular markers in clinical practice.
Virginia Arrazubi, Roberto Pazo, Dolores Isla, José Luis Pérez Gracia.
Clin Transl Oncol, 2011 Aug 09; 13(8). PMID: 21821495
Genome-wide methylation analysis identifies genes specific to breast cancer hormone receptor status and risk of recurrence.
Mary Jo Fackler, Christopher B Umbricht, +13 authors, Saraswati Sukumar.
Cancer Res, 2011 Aug 10; 71(19). PMID: 21825015    Free PMC article.
Highly Cited.
A five-gene model predicts clinical outcome in ER+/PR+, early-stage breast cancers treated with adjuvant tamoxifen.
Daniel Alan Kerr, James L Wittliff.
Horm Cancer, 2011 Aug 10; 2(5). PMID: 21826535
A multivariate model of ErbB network composition predicts ovarian cancer cell response to canertinib.
Rexxi D Prasasya, Kang Z Vang, Pamela K Kreeger.
Biotechnol Bioeng, 2011 Aug 11; 109(1). PMID: 21830205    Free PMC article.
Molecular serum portraits in patients with primary breast cancer predict the development of distant metastases.
Anders Carlsson, Christer Wingren, +10 authors, Carl A K Borrebaeck.
Proc Natl Acad Sci U S A, 2011 Aug 17; 108(34). PMID: 21844363    Free PMC article.
Endogenous knockdown of survivin improves chemotherapeutic response in ALL models.
D J Morrison, L E Hogan, +13 authors, W L Carroll.
Leukemia, 2011 Aug 17; 26(2). PMID: 21844871    Free PMC article.
Histopathological and genomic grading provide complementary prognostic information in breast cancer: a study on publicly available datasets.
Nilotpal Chowdhury.
Patholog Res Int, 2011 Aug 17; 2011. PMID: 21845210    Free PMC article.
Prognostic factors affecting postmastectomy locoregional recurrence in patients with early breast cancer: are intrinsic subtypes effective?
Hakan Mersin, Kaptan Gülben, +4 authors, Sükrü Erdoğan.
World J Surg, 2011 Aug 20; 35(10). PMID: 21853356
Prognostic and predictive markers in stage II colon cancer: is there a role for gene expression profiling?
Robin K Kelley, Alan P Venook.
Clin Colorectal Cancer, 2011 Aug 24; 10(2). PMID: 21859557    Free PMC article.
Challenges translating breast cancer gene signatures into the clinic.
Britta Weigelt, Lajos Pusztai, Alan Ashworth, Jorge S Reis-Filho.
Nat Rev Clin Oncol, 2011 Sep 01; 9(1). PMID: 21878891
Do all patients with breast cancer require systemic adjuvant therapy?
Jennifer J Griggs, Daniel F Hayes.
J Natl Cancer Inst, 2011 Sep 02; 103(18). PMID: 21881041    Free PMC article.
Genomic testing and therapies for breast cancer in clinical practice.
Jennifer S Haas, Kathryn A Phillips, +5 authors, Michele Toscano.
J Oncol Pract, 2011 Sep 03; 7(3 Suppl). PMID: 21886507    Free PMC article.
US Insurance Program's Experience With a Multigene Assay for Early-Stage Breast Cancer.
John Hornberger, Rebecca Chien, Katie Krebs, Louis Hochheiser.
J Oncol Pract, 2011 Sep 03; 7(3 Suppl). PMID: 21886510    Free PMC article.
Impact of mammographic screening on the detection of good and poor prognosis breast cancers.
Laura J Esserman, Yiwey Shieh, +8 authors, Laura J van 't Veer.
Breast Cancer Res Treat, 2011 Sep 06; 130(3). PMID: 21892702    Free PMC article.
Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer.
Ana M Gonzalez-Angulo, Bryan T Hennessy, +19 authors, Gordon B Mills.
Clin Proteomics, 2011 Sep 13; 8(1). PMID: 21906370    Free PMC article.
Clinical utility of serum tumor markers and circulating tumor cell assays in the treatment of breast cancer.
Vandana G Abramson, Ingrid A Mayer.
Curr Treat Options Oncol, 2011 Sep 16; 12(4). PMID: 21918859
Relationship between quantitative GRB7 RNA expression and recurrence after adjuvant anthracycline chemotherapy in triple-negative breast cancer.
Joseph A Sparano, Lori J Goldstein, +13 authors, Robert Gray.
Clin Cancer Res, 2011 Sep 22; 17(22). PMID: 21933890    Free PMC article.
Breast medical oncologists' use of standard prognostic factors to predict a 21-gene recurrence score.
Arif H Kamal, Charles L Loprinzi, +7 authors, Matthew P Goetz.
Oncologist, 2011 Sep 22; 16(10). PMID: 21934103    Free PMC article.
A new gene expression signature, the ClinicoMolecular Triad Classification, may improve prediction and prognostication of breast cancer at the time of diagnosis.
Dong-Yu Wang, Susan J Done, +3 authors, Wey Liang Leong.
Breast Cancer Res, 2011 Sep 24; 13(5). PMID: 21939527    Free PMC article.
Estrogen receptor (ESR1) mRNA expression and benefit from tamoxifen in the treatment and prevention of estrogen receptor-positive breast cancer.
Chungyeul Kim, Gong Tang, +18 authors, Soonmyung Paik.
J Clin Oncol, 2011 Sep 29; 29(31). PMID: 21947828    Free PMC article.
Recent progress and clinical importance on pharmacogenetics in cancer therapy.
Thomas I Peng Soh, Wei Peng Yong, Federico Innocenti.
Clin Chem Lab Med, 2011 Sep 29; 49(10). PMID: 21950596    Free PMC article.
Improving communication of breast cancer recurrence risk.
Noel T Brewer, Alice R Richman, +2 authors, Lisa A Carey.
Breast Cancer Res Treat, 2011 Oct 04; 133(2). PMID: 21964579    Free PMC article.
Insight into the heterogeneity of breast cancer through next-generation sequencing.
Hege G Russnes, Nicholas Navin, James Hicks, Anne-Lise Borresen-Dale.
J Clin Invest, 2011 Oct 04; 121(10). PMID: 21965338    Free PMC article.
Highly Cited. Review.
Animal-specific C-terminal domain links myeloblastosis oncoprotein (Myb) to an ancient repressor complex.
Laura Andrejka, Hong Wen, +5 authors, Joseph S Lipsick.
Proc Natl Acad Sci U S A, 2011 Oct 05; 108(42). PMID: 21969598    Free PMC article.
Ki 67 is a major, but not the sole determinant of Oncotype Dx recurrence score.
S Sahebjam, R Aloyz, +6 authors, L C Panasci.
Br J Cancer, 2011 Oct 06; 105(9). PMID: 21970880    Free PMC article.
A clinically relevant gene signature in triple negative and basal-like breast cancer.
Achim Rody, Thomas Karn, +11 authors, Manfred Kaufmann.
Breast Cancer Res, 2011 Oct 08; 13(5). PMID: 21978456    Free PMC article.
Highly Cited.
Prognostic gene expression signature associated with two molecularly distinct subtypes of colorectal cancer.
Sang Cheul Oh, Yun-Yong Park, +11 authors, Ju-Seog Lee.
Gut, 2011 Oct 15; 61(9). PMID: 21997556    Free PMC article.
Tumor metastasis: molecular insights and evolving paradigms.
Scott Valastyan, Robert A Weinberg.
Cell, 2011 Oct 18; 147(2). PMID: 22000009    Free PMC article.
Highly Cited. Review.
Risk of recurrence and chemotherapy benefit for patients with node-negative, estrogen receptor-positive breast cancer: recurrence score alone and integrated with pathologic and clinical factors.
Gong Tang, Jack Cuzick, +6 authors, Norman Wolmark.
J Clin Oncol, 2011 Oct 20; 29(33). PMID: 22010013    Free PMC article.
The effect of Oncotype DX recurrence score on treatment recommendations for patients with estrogen receptor-positive early stage breast cancer and correlation with estimation of recurrence risk by breast cancer specialists.
Jennifer E Joh, Nicole N Esposito, +10 authors, Geza Acs.
Oncologist, 2011 Oct 22; 16(11). PMID: 22016474    Free PMC article.
Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes.
Yoko S DeRose, Guoying Wang, +12 authors, Alana L Welm.
Nat Med, 2011 Oct 25; 17(11). PMID: 22019887    Free PMC article.
Highly Cited.
Integrating contextual miRNA and protein signatures for diagnostic and treatment decisions in cancer.
Lorenzo F Sempere.
Expert Rev Mol Diagn, 2011 Oct 26; 11(8). PMID: 22022944    Free PMC article.
Most random gene expression signatures are significantly associated with breast cancer outcome.
David Venet, Jacques E Dumont, Vincent Detours.
PLoS Comput Biol, 2011 Oct 27; 7(10). PMID: 22028643    Free PMC article.
Highly Cited.
Clinical trials in the era of personalized oncology.
Michael L Maitland, Richard L Schilsky.
CA Cancer J Clin, 2011 Oct 29; 61(6). PMID: 22034206    Free PMC article.
Effects of tissue handling on RNA integrity and microarray measurements from resected breast cancers.
Christos Hatzis, Hongxia Sun, +6 authors, W Fraser Symmans.
J Natl Cancer Inst, 2011 Oct 29; 103(24). PMID: 22034635    Free PMC article.
Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells.
Ubaldo E Martinez-Outschoorn, Allison Goldberg, +8 authors, Michael P Lisanti.
Cancer biology & therapy, 2011 Nov 02; 12(10). PMID: 22041887    Free PMC article.
Altered expression of insulin receptor isoforms in breast cancer.
Jiaqi Huang, Chris Morehouse, +12 authors, Yihong Yao.
PLoS One, 2011 Nov 03; 6(10). PMID: 22046260    Free PMC article.
Signaling pathway-based identification of extensive prognostic gene signatures for lung adenocarcinoma.
Ying-Wooi Wan, David G Beer, Nancy Lan Guo.
Lung Cancer, 2011 Nov 04; 76(1). PMID: 22047960    Free PMC article.
Molecular biology of lung cancer: clinical implications.
Jill E Larsen, John D Minna.
Clin Chest Med, 2011 Nov 08; 32(4). PMID: 22054881    Free PMC article.
Molecular characterisation of formalin-fixed paraffin-embedded (FFPE) breast tumour specimens using a custom 512-gene breast cancer bead array-based platform.
M Abramovitz, B G Barwick, +8 authors, B Leyland-Jones.
Br J Cancer, 2011 Nov 10; 105(10). PMID: 22067903    Free PMC article.
Telomere length variation in normal epithelial cells adjacent to tumor: potential biomarker for breast cancer local recurrence.
Xin Zhou, Alan K Meeker, +5 authors, Yun-Ling Zheng.
Carcinogenesis, 2011 Nov 11; 33(1). PMID: 22072619    Free PMC article.
Expression2Kinases: mRNA profiling linked to multiple upstream regulatory layers.
Edward Y Chen, Huilei Xu, +3 authors, Avi Ma'ayan.
Bioinformatics, 2011 Nov 15; 28(1). PMID: 22080467    Free PMC article.
Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment.
Peter A Fasching, Katharina Heusinger, +14 authors, David L Wachter.
BMC Cancer, 2011 Nov 16; 11. PMID: 22081974    Free PMC article.
Highly Cited.
Basal breast cancer: a complex and deadly molecular subtype.
F Bertucci, P Finetti, D Birnbaum.
Curr Mol Med, 2011 Nov 16; 12(1). PMID: 22082486    Free PMC article.
Proteomics in melanoma biomarker discovery: great potential, many obstacles.
Michael S Sabel, Yashu Liu, David M Lubman.
Int J Proteomics, 2011 Nov 16; 2011. PMID: 22084682    Free PMC article.
Using molecular markers to help predict who will fail after radical prostatectomy.
Gregory P Swanson, David Quinn.
Prostate Cancer, 2011 Nov 19; 2011. PMID: 22096655    Free PMC article.
Sixty-five gene-based risk score classifier predicts overall survival in hepatocellular carcinoma.
Soo Mi Kim, Sun-Hee Leem, +13 authors, Ju-Seog Lee.
Hepatology, 2011 Nov 23; 55(5). PMID: 22105560    Free PMC article.
Biologic characteristics of premalignant breast disease.
Kimberly Cole, Maria Tabernero, Karen S Anderson.
Cancer Biomark, 2011 Nov 25; 9(1-6). PMID: 22112476    Free PMC article.
Micro-RNAs as diagnostic or prognostic markers in human epithelial malignancies.
Angela Hui, Christine How, Emma Ito, Fei-Fei Liu.
BMC Cancer, 2011 Dec 02; 11. PMID: 22128797    Free PMC article.
The breast cancer genome--a key for better oncology.
Hans Kristian Moen Vollan, Carlos Caldas.
BMC Cancer, 2011 Dec 02; 11. PMID: 22128823    Free PMC article.
Invasive Breast Cancer: Recognition of Molecular Subtypes.
Johanna D Strehl, David L Wachter, +2 authors, Arndt Hartmann.
Breast Care (Basel), 2011 Dec 03; 6(4). PMID: 22135623    Free PMC article.
Systems cancer medicine: towards realization of predictive, preventive, personalized and participatory (P4) medicine.
Q Tian, N D Price, L Hood.
J Intern Med, 2011 Dec 07; 271(2). PMID: 22142401    Free PMC article.
Practical implications of gene-expression-based assays for breast oncologists.
Aleix Prat, Matthew J Ellis, Charles M Perou.
Nat Rev Clin Oncol, 2011 Dec 07; 9(1). PMID: 22143140    Free PMC article.
Highly Cited. Review.
Personalized cancer medicine and the future of pathology.
H Moch, P R Blank, +6 authors, T D Szucs.
Virchows Arch, 2011 Dec 07; 460(1). PMID: 22143935
Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100,000 women in 123 randomised trials.
Early Breast Cancer Trialists' Collaborative Group (EBCTCG), R Peto, +15 authors, K Pritchard.
Lancet, 2011 Dec 14; 379(9814). PMID: 22152853    Free PMC article.
Highly Cited.
Systems vaccinology: its promise and challenge for HIV vaccine development.
Helder I Nakaya, Bali Pulendran.
Curr Opin HIV AIDS, 2011 Dec 14; 7(1). PMID: 22156839    Free PMC article.
Highly sensitive proximity mediated immunoassay reveals HER2 status conversion in the circulating tumor cells of metastatic breast cancer patients.
Phillip Kim, Xinjun Liu, +8 authors, Sharat Singh.
Proteome Sci, 2011 Dec 17; 9(1). PMID: 22172159    Free PMC article.
Graph based fusion of miRNA and mRNA expression data improves clinical outcome prediction in prostate cancer.
Stephan Gade, Christine Porzelius, +6 authors, Tim Beissbarth.
BMC Bioinformatics, 2011 Dec 23; 12. PMID: 22188670    Free PMC article.
Molecular preservation by extraction and fixation, mPREF: a method for small molecule biomarker analysis and histology on exactly the same tissue.
Jeffrey R Shuster, Raymond S Lance, Dean A Troyer.
BMC Clin Pathol, 2011 Dec 23; 11. PMID: 22188997    Free PMC article.
Characterization of uncertainty in the classification of multivariate assays: application to PAM50 centroid-based genomic predictors for breast cancer treatment plans.
Mark Tw Ebbert, Roy Rl Bastien, +6 authors, Julio C Facelli.
J Clin Bioinforma, 2011 Dec 27; 1. PMID: 22196354    Free PMC article.
Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).
Laura J Esserman, Donald A Berry, +32 authors, I-SPY 1 TRIAL Investigators.
Breast Cancer Res Treat, 2011 Dec 27; 132(3). PMID: 22198468    Free PMC article.
Highly Cited.
'Omic approaches to preventing or managing metastatic breast cancer.
Obi L Griffith, Joe W Gray.
Breast Cancer Res, 2012 Jan 06; 13(6). PMID: 22216753    Free PMC article.
Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures.
Thomas Karn, Lajos Pusztai, +12 authors, Achim Rody.
PLoS One, 2012 Jan 06; 6(12). PMID: 22220191    Free PMC article.
Prognostic value of proliferation assay in the luminal, HER2-positive, and triple-negative biologic classes of breast cancer.
Mohammed A Aleskandarany, Andrew R Green, +5 authors, Emad A Rakha.
Breast Cancer Res, 2012 Jan 10; 14(1). PMID: 22225836    Free PMC article.
A three-gene model to robustly identify breast cancer molecular subtypes.
Benjamin Haibe-Kains, Christine Desmedt, +4 authors, Christos Sotiriou.
J Natl Cancer Inst, 2012 Jan 21; 104(4). PMID: 22262870    Free PMC article.
Highly Cited.
Gene expression profiling: changing face of breast cancer classification and management.
Robert Wesolowski, Bhuvaneswari Ramaswamy.
Gene Expr, 2012 Jan 25; 15(3). PMID: 22268293    Free PMC article.
A reliable method for the selection of exploitable melanoma archival paraffin embedded tissues for transcript biomarker profiling.
Celeste Lebbe, Mickael Guedj, +4 authors, Samia Mourah.
PLoS One, 2012 Jan 25; 7(1). PMID: 22272228    Free PMC article.
Role of traditional and new biomarkers in breast carcinogenesis.
D Macis, M Cazzaniga, A De Censi, B Bonanni.
Ecancermedicalscience, 2009 Jan 01; 3. PMID: 22276018    Free PMC article.
p-Medicine: From data sharing and integration via VPH models to personalized medicine.
S Rossi, Ml Christ-Neumann, +6 authors, M Delorenzi.
Ecancermedicalscience, 2012 Jan 26; 5. PMID: 22276060    Free PMC article.
Single sample expression-anchored mechanisms predict survival in head and neck cancer.
Xinan Yang, Kelly Regan, +6 authors, Yves A Lussier.
PLoS Comput Biol, 2012 Feb 01; 8(1). PMID: 22291585    Free PMC article.
A role for estrogen receptor phosphorylation in the resistance to tamoxifen.
Renée de Leeuw, Jacques Neefjes, Rob Michalides.
Int J Breast Cancer, 2012 Feb 02; 2011. PMID: 22295213    Free PMC article.
Minireview: Inflammation: an instigator of more aggressive estrogen receptor (ER) positive breast cancers.
Sarah C Baumgarten, Jonna Frasor.
Mol Endocrinol, 2012 Feb 04; 26(3). PMID: 22301780    Free PMC article.
Progranulin (GP88) tumor tissue expression is associated with increased risk of recurrence in breast cancer patients diagnosed with estrogen receptor positive invasive ductal carcinoma.
Ginette Serrero, Douglas M Hawkins, +9 authors, Wes E Kim.
Breast Cancer Res, 2012 Feb 10; 14(1). PMID: 22316048    Free PMC article.
Detection of collagen triple helix repeat containing-1 and nuclear factor (erythroid-derived 2)-like 3 in colorectal cancer.
Marco Palma, Lissett Lopez, +7 authors, María-Jose Rodriguez.
BMC Clin Pathol, 2012 Feb 11; 12. PMID: 22321245    Free PMC article.
Early breast cancer in the older woman.
Ari VanderWalde, Arti Hurria.
Clin Geriatr Med, 2012 Feb 14; 28(1). PMID: 22326036    Free PMC article.
Molecular signatures of lung cancer: defining new diagnostic and therapeutic paradigms.
Justin M Balko, Carlos L Arteaga.
Mol Diagn Ther, 2012 Feb 22; 16(1). PMID: 22339590
A gene signature for predicting outcome in patients with basal-like breast cancer.
Robin M Hallett, Anna Dvorkin-Gheva, Anita Bane, John A Hassell.
Sci Rep, 2012 Feb 23; 2. PMID: 22355741    Free PMC article.
Cancer biomarkers.
N Lynn Henry, Daniel F Hayes.
Mol Oncol, 2012 Feb 24; 6(2). PMID: 22356776    Free PMC article.
Highly Cited. Review.
Proteomics of mouse BRCA1-deficient mammary tumors identifies DNA repair proteins with potential diagnostic and prognostic value in human breast cancer.
Marc Warmoes, Janneke E Jaspers, +8 authors, Connie R Jimenez.
Mol Cell Proteomics, 2012 Mar 01; 11(7). PMID: 22366898    Free PMC article.
Maximizing biomarker discovery by minimizing gene signatures.
Chang Chang, Junwei Wang, +7 authors, Tieliu Shi.
BMC Genomics, 2012 Mar 06; 12 Suppl 5. PMID: 22369133    Free PMC article.
Decentral gene expression analysis for ER+/Her2- breast cancer: results of a proficiency testing program for the EndoPredict assay.
Carsten Denkert, Ralf Kronenwett, +23 authors, Manfred Dietel.
Virchows Arch, 2012 Mar 01; 460(3). PMID: 22371223    Free PMC article.
A semantic web framework to integrate cancer omics data with biological knowledge.
Matthew E Holford, James P McCusker, Kei-Hoi Cheung, Michael Krauthammer.
BMC Bioinformatics, 2012 Mar 01; 13 Suppl 1. PMID: 22373303    Free PMC article.
Tissue microarray-based study of patients with lymph node-positive breast cancer shows tyrosine phosphorylation of signal transducer and activator of transcription 3 (tyrosine705-STAT3) is a marker of good prognosis.
Amir Sonnenblick, Anat Shriki, +6 authors, Tamar Peretz.
Clin Transl Oncol, 2012 Mar 01; 14(3). PMID: 22374428
A prognostic gene expression profile that predicts circulating tumor cell presence in breast cancer patients.
Timothy J Molloy, Paul Roepman, Bjørn Naume, Laura J van't Veer.
PLoS One, 2012 Mar 03; 7(2). PMID: 22384245    Free PMC article.
Breast cancer local therapy: what is its effect on mortality?
John R Benson, Katy A T Teo.
World J Surg, 2012 Mar 07; 36(7). PMID: 22392352
Integrative Analysis of Response to Tamoxifen Treatment in ER-Positive Breast Cancer Using GWAS Information and Transcription Profiling.
Chindo Hicks, Ranjit Kumar, Antonio Pannuti, Lucio Miele.
Breast Cancer (Auckl), 2012 Mar 09; 6. PMID: 22399860    Free PMC article.
Protease-activated drug development.
Ki Young Choi, Magdalena Swierczewska, Seulki Lee, Xiaoyuan Chen.
Theranostics, 2012 Mar 09; 2(2). PMID: 22400063    Free PMC article.
Hormonal therapy in breast cancer: a model disease for the personalization of cancer care.
Shannon Puhalla, Saveri Bhattacharya, Nancy E Davidson.
Mol Oncol, 2012 Mar 13; 6(2). PMID: 22406404    Free PMC article.
Targeting survivin in cancer.
Dario C Altieri.
Cancer Lett, 2012 Mar 14; 332(2). PMID: 22410464    Free PMC article.
Highly Cited. Review.
Agreement in risk prediction between the 21-gene recurrence score assay (Oncotype DX®) and the PAM50 breast cancer intrinsic Classifier™ in early-stage estrogen receptor-positive breast cancer.
Catherine M Kelly, Philip S Bernard, +7 authors, Lajos Pusztai.
Oncologist, 2012 Mar 16; 17(4). PMID: 22418568    Free PMC article.
Impact of preanalytic factors on the design and application of integral biomarkers for directing patient therapy.
Stephen M Hewitt, Sunil S Badve, Lawrence D True.
Clin Cancer Res, 2012 Mar 17; 18(6). PMID: 22422404    Free PMC article.
Industrial methodology for process verification in research (IMPROVER): toward systems biology verification.
Pablo Meyer, Julia Hoeng, +8 authors, Gustavo Stolovitzky.
Bioinformatics, 2012 Mar 17; 28(9). PMID: 22423044    Free PMC article.
Patients with positive axillary lymph nodes: how to use genomic assays.
Ruta Rao.
Curr Treat Options Oncol, 2012 Mar 20; 13(2). PMID: 22426945
Molecular staging individualizing cancer management.
Alex Mejia, Stephanie Schulz, +2 authors, Scott A Waldman.
J Surg Oncol, 2012 Mar 24; 105(5). PMID: 22441898    Free PMC article.
Comparison of the RNA-based EndoPredict multigene test between core biopsies and corresponding surgical breast cancer sections.
Berit Maria Müller, Jan C Brase, +7 authors, Carsten Denkert.
J Clin Pathol, 2012 Mar 27; 65(7). PMID: 22447922    Free PMC article.
Seventeen-gene signature from enriched Her2/Neu mammary tumor-initiating cells predicts clinical outcome for human HER2+:ERα- breast cancer.
Jeff C Liu, Veronique Voisin, +6 authors, Eldad Zacksenhaus.
Proc Natl Acad Sci U S A, 2012 Mar 31; 109(15). PMID: 22460789    Free PMC article.
Pharmacogenetics: implementing personalized medicine.
Enrico Mini, Stefania Nobili.
Clin Cases Miner Bone Metab, 2009 Jan 01; 6(1). PMID: 22461093    Free PMC article.
Toward individualized breast cancer therapy: translating biological concepts to the bedside.
Gabriel N Hortobagyi.
Oncologist, 2012 Apr 05; 17(4). PMID: 22474069    Free PMC article.
Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia.
Teena Bhatla, Jinhua Wang, +4 authors, William L Carroll.
Blood, 2012 Apr 13; 119(22). PMID: 22496163    Free PMC article.
Building the evidence base for decision making in cancer genomic medicine using comparative effectiveness research.
Katrina A B Goddard, William A Knaus, +8 authors, David L Veenstra.
Genet Med, 2012 Apr 21; 14(7). PMID: 22516979    Free PMC article.
Assessment of the contribution of the IHC4+C score to decision making in clinical practice in early breast cancer.
S Barton, L Zabaglo, +6 authors, M Dowsett.
Br J Cancer, 2012 Apr 26; 106(11). PMID: 22531639    Free PMC article.
Concordance among gene expression-based predictors for ER-positive breast cancer treated with adjuvant tamoxifen.
A Prat, J S Parker, +9 authors, C M Perou.
Ann Oncol, 2012 Apr 26; 23(11). PMID: 22532584    Free PMC article.
Aurora kinase A outperforms Ki67 as a prognostic marker in ER-positive breast cancer.
H R Ali, S-J Dawson, +3 authors, C Caldas.
Br J Cancer, 2012 Apr 28; 106(11). PMID: 22538974    Free PMC article.
Next generation sequencing and a new era of medicine.
Graham Casey, David Conti, Robert Haile, David Duggan.
Gut, 2012 May 03; 62(6). PMID: 22550129    Free PMC article.
Results of the First Austrian Multidisciplinary Expert Panel on Controversies in Local Treatment of Breast Cancer.
Michael Knauer, Michael Gnant, Florian Fitzal.
Breast Care (Basel), 2012 May 04; 7(1). PMID: 22553475    Free PMC article.
Gene expression profiling of papillary thyroid carcinomas in Korean patients by oligonucleotide microarrays.
Ki-Wook Chung, Seok Won Kim, Sun Wook Kim.
J Korean Surg Soc, 2012 May 09; 82(5). PMID: 22563533    Free PMC article.
A target based approach identifies genomic predictors of breast cancer patient response to chemotherapy.
Robin M Hallett, Gregory Pond, John A Hassell.
BMC Med Genomics, 2012 May 15; 5. PMID: 22578285    Free PMC article.
Tumor markers in clinical practice: a review focusing on common solid cancers.
Michael J Duffy.
Med Princ Pract, 2012 May 16; 22(1). PMID: 22584792    Free PMC article.
Adoption of gene expression profile testing and association with use of chemotherapy among women with breast cancer.
Michael J Hassett, Samuel M Silver, +12 authors, Jane C Weeks.
J Clin Oncol, 2012 May 16; 30(18). PMID: 22585699    Free PMC article.
Poor-prognosis estrogen receptor- positive disease: present and future clinical solutions.
Per E Lønning.
Ther Adv Med Oncol, 2012 May 17; 4(3). PMID: 22590486    Free PMC article.
A methodological approach to unravel organ-specific breast cancer metastasis.
Sébastien Nola, Soraya Sin, +2 authors, Keltouma Driouch.
J Mammary Gland Biol Neoplasia, 2012 May 26; 17(2). PMID: 22628182
The implications of breast cancer molecular phenotype for radiation oncology.
Shirin Sioshansi, Kathryn E Huber, David E Wazer.
Front Oncol, 2011 Jan 01; 1. PMID: 22649753    Free PMC article.
NT5E CpG island methylation is a favourable breast cancer biomarker.
C Lo Nigro, M Monteverde, +17 authors, T Crook.
Br J Cancer, 2012 Jun 02; 107(1). PMID: 22653144    Free PMC article.
Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance.
Justin M Balko, Rebecca S Cook, +15 authors, Carlos L Arteaga.
Nat Med, 2012 Jun 12; 18(7). PMID: 22683778    Free PMC article.
Highly Cited.
The role of targeted therapy and biomarkers in breast cancer treatment.
Alison T Stopeck, Ursa Brown-Glaberman, +5 authors, Hope S Rugo.
Clin Exp Metastasis, 2012 Jun 14; 29(7). PMID: 22692561
Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression.
Todd P Knutson, Andrea R Daniel, +4 authors, Carol A Lange.
Breast Cancer Res, 2012 Jun 16; 14(3). PMID: 22697792    Free PMC article.
TOP2A RNA expression and recurrence in estrogen receptor-positive breast cancer.
Joseph A Sparano, Lori J Goldstein, +2 authors, Robert Gray.
Breast Cancer Res Treat, 2012 Jun 19; 134(2). PMID: 22706628    Free PMC article.
Expression of the BRCA1 complex member BRE predicts disease free survival in breast cancer.
Sylvie M Noordermeer, Marloes Wennemers, +6 authors, Bert A van der Reijden.
Breast Cancer Res Treat, 2012 Jun 19; 135(1). PMID: 22706632    Free PMC article.
Predicting the response to preoperative radiation or chemoradiation by a microarray analysis of the gene expression profiles in rectal cancer.
Takashi Akiyoshi, Takashi Kobunai, Toshiaki Watanabe.
Surg Today, 2012 Jun 19; 42(8). PMID: 22706722
A 50-gene intrinsic subtype classifier for prognosis and prediction of benefit from adjuvant tamoxifen.
Stephen K Chia, Vivien H Bramwell, +12 authors, Torsten O Nielsen.
Clin Cancer Res, 2012 Jun 20; 18(16). PMID: 22711706    Free PMC article.
Highly Cited.
Tumour biomarker expression relative to age and molecular subtypes of invasive breast cancer.
D H Morrison, D Rahardja, +2 authors, V R Sarode.
Br J Cancer, 2012 Jun 21; 107(2). PMID: 22713661    Free PMC article.
Amplified loci on chromosomes 8 and 17 predict early relapse in ER-positive breast cancers.
Erhan Bilal, Kristen Vassallo, +8 authors, Shridar Ganesan.
PLoS One, 2012 Jun 22; 7(6). PMID: 22719901    Free PMC article.
Genomics: the breast cancer landscape.
Joe Gray, Brian Druker.
Nature, 2012 Jun 23; 486(7403). PMID: 22722187
Why does Oncotype DX recurrence score reduce adjuvant chemotherapy use?
Jeffrey G Schneider, Danny N Khalil.
Breast Cancer Res Treat, 2012 Jun 23; 134(3). PMID: 22723033    Free PMC article.
MicroRNA-9 as potential biomarker for breast cancer local recurrence and tumor estrogen receptor status.
Xin Zhou, Catalin Marian, +4 authors, Yun-Ling Zheng.
PLoS One, 2012 Jun 23; 7(6). PMID: 22723919    Free PMC article.
GUCY2C molecular staging personalizes colorectal cancer patient management.
Jian P Gong, Stephanie Schulz, Terry Hyslop, Scott A Waldman.
Biomark Med, 2012 Jun 27; 6(3). PMID: 22731908    Free PMC article.
Association of sleep duration and breast cancer OncotypeDX recurrence score.
Cheryl L Thompson, Li Li.
Breast Cancer Res Treat, 2012 Jul 04; 134(3). PMID: 22752291    Free PMC article.
Personalized therapy for urothelial cancer: review of the clinical evidence.
Elizabeth A Guancial, Dipanjan Chowdhury, Jonathan E Rosenberg.
Clin Investig (Lond), 2011 Apr 01; 1(4). PMID: 22754656    Free PMC article.
Signatures of tumor-immune interactions as biomarkers for breast cancer prognosis.
Masoud H Manjili, Kayvan Najarian, Xiang-Yang Wang.
Future Oncol, 2012 Jul 07; 8(6). PMID: 22764768    Free PMC article.
Integration of breast cancer gene signatures based on graph centrality.
Jianxin Wang, Gang Chen, Min Li, Yi Pan.
BMC Syst Biol, 2012 Jul 20; 5 Suppl 3. PMID: 22784616    Free PMC article.
A novel survival-based tissue microarray of pancreatic cancer validates MUC1 and mesothelin as biomarkers.
Jordan M Winter, Laura H Tang, +11 authors, Peter J Allen.
PLoS One, 2012 Jul 14; 7(7). PMID: 22792233    Free PMC article.
Personalized Combined Modality Therapy for Locally Advanced Non-small Cell Lung Cancer.
D Nathan Kim, Taek-Keun Nam, Kevin S Choe, Hak Choy.
Cancer Res Treat, 2012 Jul 18; 44(2). PMID: 22802745    Free PMC article.
Cancer develops, progresses and responds to therapies through restricted perturbation of the protein-protein interaction network.
Jordi Serra-Musach, Helena Aguilar, +5 authors, Miguel Angel Pujana.
Integr Biol (Camb), 2012 Jul 19; 4(9). PMID: 22806580    Free PMC article.
Whole transcriptome RNA-Seq analysis of breast cancer recurrence risk using formalin-fixed paraffin-embedded tumor tissue.
Dominick Sinicropi, Kunbin Qu, +14 authors, Joffre Baker.
PLoS One, 2012 Jul 19; 7(7). PMID: 22808097    Free PMC article.
Integration of clinical and gene expression data has a synergetic effect on predicting breast cancer outcome.
Martin H van Vliet, Hugo M Horlings, +2 authors, Lodewyk F A Wessels.
PLoS One, 2012 Jul 19; 7(7). PMID: 22808140    Free PMC article.
Multi-field-of-view strategy for image-based outcome prediction of multi-parametric estrogen receptor-positive breast cancer histopathology: Comparison to Oncotype DX.
Ajay Basavanhally, Michael Feldman, +4 authors, Anant Madabhushi.
J Pathol Inform, 2011 Jan 01; 2. PMID: 22811953    Free PMC article.
High-risk estrogen-receptor-positive breast cancer: identification and implications for therapy.
Rosemary L Balleine, Nicholas R Wilcken.
Mol Diagn Ther, 2012 Jul 21; 16(4). PMID: 22812573
Can predictive biomarkers in breast cancer guide adjuvant endocrine therapy?
Karin Beelen, Wilbert Zwart, Sabine C Linn.
Nat Rev Clin Oncol, 2012 Jul 25; 9(9). PMID: 22825374
Validation of a radiosensitivity molecular signature in breast cancer.
Steven A Eschrich, William J Fulp, +9 authors, Javier F Torres-Roca.
Clin Cancer Res, 2012 Jul 27; 18(18). PMID: 22832933    Free PMC article.
Three-gene signature predicts disease progression of non-muscle invasive bladder cancer.
Pildu Jeong, Yun-Sok Ha, +6 authors, Wun-Jae Kim.
Oncol Lett, 2012 Aug 01; 2(4). PMID: 22848249    Free PMC article.
The prognostic importance of cathepsin D and E-cadherin in early breast cancer: A single-institution experience.
Galia Jacobson-Raber, Irena Lazarev, +5 authors, Samuel Ariad.
Oncol Lett, 2012 Aug 01; 2(6). PMID: 22848286    Free PMC article.
Tumor associated macrophage × cancer cell hybrids may acquire cancer stem cell properties in breast cancer.
Jingxian Ding, Wei Jin, +2 authors, Jiong Wu.
PLoS One, 2012 Aug 01; 7(7). PMID: 22848668    Free PMC article.
Multiplicities in cancer research: ubiquitous and necessary evils.
Donald Berry.
J Natl Cancer Inst, 2012 Aug 04; 104(15). PMID: 22859849    Free PMC article.
Understanding how breast cancer patients use risk information from genomic tests.
Jessica T DeFrank, Lisa A Carey, Noel T Brewer.
J Behav Med, 2012 Aug 11; 36(6). PMID: 22878783    Free PMC article.
Discordant cellular response to presurgical letrozole in bilateral synchronous ER+ breast cancers with a KRAS mutation or FGFR1 gene amplification.
Justin M Balko, Ingrid A Mayer, +6 authors, Carlos L Arteaga.
Molecular cancer therapeutics, 2012 Aug 11; 11(10). PMID: 22879364    Free PMC article.
Multiwalled carbon nanotube-induced gene signatures in the mouse lung: potential predictive value for human lung cancer risk and prognosis.
Nancy L Guo, Ying-Wooi Wan, +5 authors, Yong Qian.
J Toxicol Environ Health A, 2012 Aug 16; 75(18). PMID: 22891886    Free PMC article.
The non-crosslinking fixative RCL2®-CS100 is compatible with both pathology diagnosis and molecular analyses.
Florence Boissière-Michot, Amélie Denouël, +5 authors, Frédéric Bibeau.
Pathol Oncol Res, 2012 Aug 16; 19(1). PMID: 22893391
Identification of new candidate therapeutic target genes in triple-negative breast cancer.
Mathilde Glénisson, Sophie Vacher, +8 authors, Ivan Bièche.
Genes Cancer, 2012 Aug 16; 3(1). PMID: 22893791    Free PMC article.
Developing and validating continuous genomic signatures in randomized clinical trials for predictive medicine.
Shigeyuki Matsui, Richard Simon, +3 authors, John Crowley.
Clin Cancer Res, 2012 Aug 29; 18(21). PMID: 22927484    Free PMC article.
Treatment Choices Based on OncotypeDx in the Breast Oncology Care Setting.
Teri L Malo, Isaac Lipkus, +3 authors, Susan T Vadaparampil.
J Cancer Epidemiol, 2012 Aug 29; 2012. PMID: 22927848    Free PMC article.
Role of immune escape mechanisms in Hodgkin's lymphoma development and progression: a whole new world with therapeutic implications.
Luis de la Cruz-Merino, Marylène Lejeune, +6 authors, Tomás Álvaro.
Clin Dev Immunol, 2012 Aug 29; 2012. PMID: 22927872    Free PMC article.
A sample selection strategy to boost the statistical power of signature detection in cancer expression profile studies.
Zhenyu Jia, Yipeng Wang, +8 authors, Dan Mercola.
Anticancer Agents Med Chem, 2012 Sep 01; 13(2). PMID: 22934703    Free PMC article.
The molecular profile of luminal B breast cancer.
Chad J Creighton.
Biologics, 2012 Sep 08; 6. PMID: 22956860    Free PMC article.
A single-sample microarray normalization method to facilitate personalized-medicine workflows.
Stephen R Piccolo, Ying Sun, +3 authors, W Evan Johnson.
Genomics, 2012 Sep 11; 100(6). PMID: 22959562    Free PMC article.
Highly Cited.
From drug discovery to biomarker-driven clinical trials in lymphoma.
Anas Younes, Donald A Berry.
Nat Rev Clin Oncol, 2012 Sep 12; 9(11). PMID: 22965151    Free PMC article.
Elevated thymidine kinase 1 in serum following neoadjuvant chemotherapy predicts poor outcome for patients with locally advanced breast cancer.
Zhi-Heng Huang, Xing-Song Tian, +4 authors, Ya-Jie Yang.
Exp Ther Med, 2012 Sep 13; 3(2). PMID: 22969891    Free PMC article.
Development and validation of a prognostic gene-expression signature for lung adenocarcinoma.
Yun-Yong Park, Eun Sung Park, +7 authors, Ju-Seog Lee.
PLoS One, 2012 Sep 13; 7(9). PMID: 22970185    Free PMC article.
Cost-effectiveness of the 21-gene recurrence score assay in the context of multifactorial decision making to guide chemotherapy for early-stage breast cancer.
Shelby D Reed, Michaela A Dinan, Kevin A Schulman, Gary H Lyman.
Genet Med, 2012 Sep 15; 15(3). PMID: 22975761    Free PMC article.
Guidelines for locoregional therapy in primary breast cancer in developing countries: The results of an expert panel at the 8(th) Annual Women's Cancer Initiative - Tata Memorial Hospital (WCI-TMH) Conference.
Anusheel Munshi, Sudeep Gupta, +12 authors, other Locoregional Panel Members.
Indian J Med Paediatr Oncol, 2012 Sep 19; 33(2). PMID: 22988354    Free PMC article.
Ki-67 as a prognostic marker according to breast cancer subtype and a predictor of recurrence time in primary breast cancer.
Reiki Nishimura, Tomofumi Osako, +3 authors, Nobuyuki Arima.
Exp Ther Med, 2010 Sep 01; 1(5). PMID: 22993598    Free PMC article.
Comprehensive molecular portraits of human breast tumours.
Cancer Genome Atlas Network.
Nature, 2012 Sep 25; 490(7418). PMID: 23000897    Free PMC article.
Highly Cited.
A multichannel Markov random field framework for tumor segmentation with an application to classification of gene expression-based breast cancer recurrence risk.
Ahmed B Ashraf, Sara C Gavenonis, +3 authors, Despina Kontos.
IEEE Trans Med Imaging, 2012 Sep 26; 32(4). PMID: 23008246    Free PMC article.
Translating mathematical modeling of tumor growth patterns into novel therapeutic approaches for breast cancer.
Elizabeth Comen, Patrick G Morris, Larry Norton.
J Mammary Gland Biol Neoplasia, 2012 Sep 27; 17(3-4). PMID: 23011603
Study designs and statistical analyses for biomarker research.
Masahiko Gosho, Kengo Nagashima, Yasunori Sato.
Sensors (Basel), 2012 Sep 27; 12(7). PMID: 23012528    Free PMC article.
Perspectives on an education in computational biology and medicine.
Jill C Rubinstein.
Yale J Biol Med, 2012 Sep 27; 85(3). PMID: 23012581    Free PMC article.
Immunoglobulin kappa C predicts overall survival in node-negative breast cancer.
Zonglin Chen, Aslihan Gerhold-Ay, +13 authors, Marcus Schmidt.
PLoS One, 2012 Oct 03; 7(9). PMID: 23028600    Free PMC article.
Identification of common prognostic gene expression signatures with biological meanings from microarray gene expression datasets.
Jun Yao, Qi Zhao, +4 authors, John N Weinstein.
PLoS One, 2012 Oct 03; 7(9). PMID: 23029298    Free PMC article.
Cost-effectiveness of a 21-gene recurrence score assay versus Canadian clinical practice in women with early-stage estrogen- or progesterone-receptor-positive, axillary lymph-node negative breast cancer.
Malek B Hannouf, Bin Xie, Muriel Brackstone, Gregory S Zaric.
BMC Cancer, 2012 Oct 04; 12. PMID: 23031196    Free PMC article.
EndoPredict improves the prognostic classification derived from common clinical guidelines in ER-positive, HER2-negative early breast cancer.
P Dubsky, M Filipits, +17 authors, Austrian Breast and Colorectal Cancer Study Group (ABCSG).
Ann Oncol, 2012 Oct 05; 24(3). PMID: 23035151    Free PMC article.
PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers.
Roy R L Bastien, Álvaro Rodríguez-Lescure, +29 authors, Miguel Martín.
BMC Med Genomics, 2012 Oct 06; 5. PMID: 23035882    Free PMC article.
Highly Cited.
Decentral gene expression analysis: analytical validation of the Endopredict genomic multianalyte breast cancer prognosis test.
Ralf Kronenwett, Kerstin Bohmann, +16 authors, Carsten Denkert.
BMC Cancer, 2012 Oct 09; 12. PMID: 23039280    Free PMC article.
A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis.
Nathan E Reticker-Flynn, David F Braga Malta, +6 authors, Sangeeta N Bhatia.
Nat Commun, 2012 Oct 11; 3. PMID: 23047680    Free PMC article.
Highly Cited.
Molecular alterations associated with breast cancer mortality.
Laura M Voeghtly, Kim Mamula, +2 authors, Rachel E Ellsworth.
PLoS One, 2012 Oct 12; 7(10). PMID: 23056464    Free PMC article.
[Translational research and diagnostics for breast cancer].
H H Kreipe.
Pathologe, 2012 Oct 16; 33 Suppl 2. PMID: 23064514
Imputing gene expression from selectively reduced probe sets.
Yoni Donner, Ting Feng, Christophe Benoist, Daphne Koller.
Nat Methods, 2012 Oct 16; 9(11). PMID: 23064520    Free PMC article.
Gene expression profiling for guiding adjuvant chemotherapy decisions in women with early breast cancer: an evidence-based and economic analysis.
Medical Advisory Secretariat.
Ont Health Technol Assess Ser, 2010 Jan 01; 10(23). PMID: 23074401    Free PMC article.
Are we ready to stratify treatment for diffuse large B-cell lymphoma using molecular hallmarks?
Sarah Barton, Eliza A Hawkes, Andrew Wotherspoon, David Cunningham.
Oncologist, 2012 Oct 23; 17(12). PMID: 23086691    Free PMC article.
Aberrations in translational regulation are associated with poor prognosis in hormone receptor-positive breast cancer.
Funda Meric-Bernstam, Huiqin Chen, +6 authors, Ana Gonzalez-Angulo.
Breast Cancer Res, 2012 Oct 30; 14(5). PMID: 23102376    Free PMC article.
A molecular assay of tumor radiosensitivity: a roadmap towards biology-based personalized radiation therapy.
Javier F Torres-Roca.
Per Med, 2012 Oct 30; 9(5). PMID: 23105945    Free PMC article.
Non-gaussian distributions affect identification of expression patterns, functional annotation, and prospective classification in human cancer genomes.
Nicholas F Marko, Robert J Weil.
PLoS One, 2012 Nov 03; 7(10). PMID: 23118863    Free PMC article.
The 21-gene recurrence score assay impacts adjuvant therapy recommendations for ER-positive, node-negative and node-positive early breast cancer resulting in a risk-adapted change in chemotherapy use.
W Eiermann, M Rezai, +13 authors, J Blohmer.
Ann Oncol, 2012 Nov 09; 24(3). PMID: 23136233    Free PMC article.
Metabolomics approach for predicting response to neoadjuvant chemotherapy for breast cancer.
Siwei Wei, Lingyan Liu, +8 authors, Daniel Raftery.
Mol Oncol, 2012 Nov 13; 7(3). PMID: 23142658    Free PMC article.
The prognostic and predictive value of mRNA expression of vascular endothelial growth factor family members in breast cancer: a study in primary tumors of high-risk early breast cancer patients participating in a randomized Hellenic Cooperative Oncology Group trial.
Helena Linardou, Konstantine T Kalogeras, +10 authors, George Fountzilas.
Breast Cancer Res, 2012 Nov 14; 14(6). PMID: 23146280    Free PMC article.
Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors.
Marcus Schmidt, Patrick Micke, Mathias Gehrmann, Jan G Hengstler.
Oncoimmunology, 2012 Nov 22; 1(7). PMID: 23170262    Free PMC article.
Accelerated partial breast irradiation for early-stage breast cancer: controversies and current indications for use.
Lisa C Klepczyk, Kimberly S Keene, Jennifer F De Los Santos.
Curr Treat Options Oncol, 2012 Nov 28; 14(1). PMID: 23179757
Barriers to the use of personalized medicine in breast cancer.
Christine B Weldon, Julia R Trosman, +2 authors, Julian C Schink.
J Oncol Pract, 2012 Nov 28; 8(4). PMID: 23180995    Free PMC article.
New perspectives for in vitro risk assessment of multiwalled carbon nanotubes: application of coculture and bioinformatics.
Brandi N Snyder-Talkington, Yong Qian, Vincent Castranova, Nancy L Guo.
J Toxicol Environ Health B Crit Rev, 2012 Nov 30; 15(7). PMID: 23190270    Free PMC article.
Moving from correlative science to predictive oncology.
Richard Simon.
EPMA J, 2010 Sep 01; 1(3). PMID: 23199082    Free PMC article.
Prediction and prognosis: impact of gene expression profiling in personalized treatment of breast cancer patients.
Michael R Mallmann, Andrea Staratschek-Jox, +5 authors, Joachim L Schultze.
EPMA J, 2010 Sep 01; 1(3). PMID: 23199086    Free PMC article.
Challenges and solutions in the development of genomic biomarker panels: a systematic phased approach.
K Shahzad, A Fatima, +5 authors, Mc Deng.
Curr Genomics, 2012 Dec 04; 13(4). PMID: 23204923    Free PMC article.
Phosphorylation of p90RSK is associated with increased response to neoadjuvant chemotherapy in ER-positive breast cancer.
Hyeong-Gon Moon, Jae Kyo Yi, +9 authors, Dong-Young Noh.
BMC Cancer, 2012 Dec 12; 12. PMID: 23216670    Free PMC article.
Molecular profiles of pre- and postoperative breast cancer tumours reveal differentially expressed genes.
Margit L H Riis, Torben Lüders, +4 authors, Ida R K Bukholm.
ISRN Oncol, 2012 Dec 12; 2012. PMID: 23227362    Free PMC article.
Treatment when prognostic factors do not match St. Gallen recommendations: profiling of prognostic factors among HR(+) and HER2(-) breast cancer patients.
Kyoko Satoh, Maki Tanaka, +2 authors, Tatsuyuki Kakuma.
World J Surg, 2012 Dec 12; 37(3). PMID: 23229849
Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis.
Francesco Niola, Xudong Zhao, +13 authors, Anna Lasorella.
J Clin Invest, 2012 Dec 18; 123(1). PMID: 23241957    Free PMC article.
Basal/HER2 breast carcinomas: integrating molecular taxonomy with cancer stem cell dynamics to predict primary resistance to trastuzumab (Herceptin).
Begoña Martin-Castillo, Cristina Oliveras-Ferraros, +7 authors, Javier A Menendez.
Cell cycle (Georgetown, Tex.), 2012 Dec 21; 12(2). PMID: 23255137    Free PMC article.
Prognostically relevant gene signatures of high-grade serous ovarian carcinoma.
Roel G W Verhaak, Pablo Tamayo, +39 authors, Cancer Genome Atlas Research Network.
J Clin Invest, 2012 Dec 22; 123(1). PMID: 23257362    Free PMC article.
Highly Cited.
Sample parameters affecting the clinical relevance of RNA biomarkers in translational breast cancer research.
Vassiliki Kotoula, Konstantine T Kalogeras, +4 authors, George Fountzilas.
Virchows Arch, 2012 Dec 25; 462(2). PMID: 23262785    Free PMC article.
Rational design of the survivin/CDK4 complex by combining protein-protein docking and molecular dynamics simulations.
Jana Selent, Agnieszka A Kaczor, +3 authors, Cristian Obiol-Pardo.
J Mol Model, 2012 Dec 25; 19(4). PMID: 23263360
Omics Screening for Pharmaceutical Efficacy and Safety in Clinical Practice.
Andrew A Monte, Vasilis Vasiliou, Kennon J Heard.
J Pharmacogenomics Pharmacoproteomics, 2012 Dec 25; S5. PMID: 23264882    Free PMC article.
14-3-3ζ as a predictor of early time to recurrence and distant metastasis in hormone receptor-positive and -negative breast cancers.
Anna Bergamaschi, Jonna Frasor, +5 authors, Benita S Katzenellenbogen.
Breast Cancer Res Treat, 2012 Dec 29; 137(3). PMID: 23271328    Free PMC article.
Oncoshare: lessons learned from building an integrated multi-institutional database for comparative effectiveness research.
Susan C Weber, Tina Seto, +3 authors, Amar K Das.
AMIA Annu Symp Proc, 2013 Jan 11; 2012. PMID: 23304372    Free PMC article.
Towards mechanism classifiers: expression-anchored Gene Ontology signature predicts clinical outcome in lung adenocarcinoma patients.
Xinan Yang, Haiquan Li, +3 authors, Yves A Lussier.
AMIA Annu Symp Proc, 2013 Jan 11; 2012. PMID: 23304380    Free PMC article.
Selecting cases for whom additional tests can improve prognostication.
Xiaoqian Jiang, Jihoon Kim, +2 authors, Lucila Ohno-Machado.
AMIA Annu Symp Proc, 2013 Jan 11; 2012. PMID: 23304404    Free PMC article.
The genomic landscape of breast cancer as a therapeutic roadmap.
Matthew J Ellis, Charles M Perou.
Cancer Discov, 2013 Jan 16; 3(1). PMID: 23319768    Free PMC article.
Highly Cited.
A 13-gene signature prognostic of HPV-negative OSCC: discovery and external validation.
Pawadee Lohavanichbutr, Eduardo Méndez, +8 authors, Chu Chen.
Clin Cancer Res, 2013 Jan 16; 19(5). PMID: 23319825    Free PMC article.
Markedly additive antitumor activity with the combination of a selective survivin suppressant YM155 and alemtuzumab in adult T-cell leukemia.
Jing Chen, Cynthia A Pise-Masison, +5 authors, Thomas A Waldmann.
Blood, 2013 Jan 17; 121(11). PMID: 23321252    Free PMC article.
Gene signatures in breast cancer: current and future uses.
Enrique Espinosa Arranz, Juan Ángel Fresno Vara, Angelo Gámez-Pozo, Pilar Zamora.
Transl Oncol, 2013 Jan 17; 5(6). PMID: 23323153    Free PMC article.
Engaging in health behaviors to lower risk for breast cancer recurrence.
Suzanne C O'Neill, Jessica T DeFrank, +4 authors, Noel T Brewer.
PLoS One, 2013 Jan 18; 8(1). PMID: 23326466    Free PMC article.
A genomic approach to active surveillance: a step toward precision medicine.
Eric A Klein.
Asian J Androl, 2013 Jan 22; 15(3). PMID: 23334203    Free PMC article.
Challenges in Biomarker Discovery: Combining Expert Insights with Statistical Analysis of Complex Omics Data.
Jason E McDermott, Jing Wang, +4 authors, Karin D Rodland.
Expert Opin Med Diagn, 2013 Jan 22; 7(1). PMID: 23335946    Free PMC article.
Utility of prognostic genomic tests in breast cancer practice: The IMPAKT 2012 Working Group Consensus Statement.
H A Azim, S Michiels, +9 authors, C Swanton.
Ann Oncol, 2013 Jan 23; 24(3). PMID: 23337633    Free PMC article.
Patient-derived breast tumor xenografts facilitating personalized cancer therapy.
Melissa D Landis, Brian D Lehmann, Jennifer A Pietenpol, Jenny C Chang.
Breast Cancer Res, 2013 Jan 24; 15(1). PMID: 23339383    Free PMC article.
Citizens' perspectives on personalized medicine: a qualitative public deliberation study.
Yvonne Bombard, Julia Abelson, Dorina Simeonov, Francois-Pierre Gauvin.
Eur J Hum Genet, 2013 Jan 24; 21(11). PMID: 23340511    Free PMC article.
Germline DNA copy number aberrations identified as potential prognostic factors for breast cancer recurrence.
Yadav Sapkota, Sunita Ghosh, +5 authors, Sambasivarao Damaraju.
PLoS One, 2013 Jan 24; 8(1). PMID: 23342018    Free PMC article.
Gene expression signatures that predict outcome of tamoxifen-treated estrogen receptor-positive, high-risk, primary breast cancer patients: a DBCG study.
Maria B Lyng, Anne-Vibeke Lænkholm, +4 authors, Henrik J Ditzel.
PLoS One, 2013 Jan 24; 8(1). PMID: 23342080    Free PMC article.
Vav1 fine tunes p53 control of apoptosis versus proliferation in breast cancer.
Shulamit Sebban, Marganit Farago, +4 authors, Shulamit Katzav.
PLoS One, 2013 Jan 24; 8(1). PMID: 23342133    Free PMC article.
Personalized cancer medicine: molecular diagnostics, predictive biomarkers, and drug resistance.
D Gonzalez de Castro, P A Clarke, B Al-Lazikani, P Workman.
Clin Pharmacol Ther, 2013 Jan 31; 93(3). PMID: 23361103    Free PMC article.
Highly Cited. Review.
Translating metastasis-related biomarkers to the clinic--progress and pitfalls.
François-Clément Bidard, Jean-Yves Pierga, Jean-Charles Soria, Jean Paul Thiery.
Nat Rev Clin Oncol, 2013 Feb 06; 10(3). PMID: 23381003
A data similarity-based strategy for meta-analysis of transcriptional profiles in cancer.
Qingchao Qiu, Pengcheng Lu, +6 authors, Yajun Yi.
PLoS One, 2013 Feb 06; 8(1). PMID: 23383020    Free PMC article.
A simple immunohistochemical panel comprising 2 conventional markers, Ki67 and p53, is a powerful tool for predicting patient outcome in luminal-type breast cancer.
Takayuki Kobayashi, Keiichi Iwaya, +4 authors, Osamu Matsubara.
BMC Clin Pathol, 2013 Feb 07; 13. PMID: 23384409    Free PMC article.
Guanylyl cyclase C as a biomarker in colorectal cancer.
Terry Hyslop, Scott A Waldman.
Biomark Med, 2013 Feb 08; 7(1). PMID: 23387497    Free PMC article.
A new genome-driven integrated classification of breast cancer and its implications.
Sarah-Jane Dawson, Oscar M Rueda, Samuel Aparicio, Carlos Caldas.
EMBO J, 2013 Feb 12; 32(5). PMID: 23395906    Free PMC article.
Highly Cited. Review.
Where medicine, business, and public policy intersect.
Chantell L Wilson, Stephanie Schultz, Scott A Waldman.
Biotechnol Healthc, 2007 Feb 01; 4(1). PMID: 23397413    Free PMC article.
Biclustering reveals breast cancer tumour subgroups with common clinical features and improves prediction of disease recurrence.
Yi Kan Wang, Cristin G Print, Edmund J Crampin.
BMC Genomics, 2013 Feb 15; 14. PMID: 23405961    Free PMC article.
Essential nontranslational functions of tRNA synthetases.
Min Guo, Paul Schimmel.
Nat Chem Biol, 2013 Feb 19; 9(3). PMID: 23416400    Free PMC article.
Highly Cited. Review.
Risk assessment, disease prevention and personalised treatments in breast cancer: is clinically qualified integrative approach in the horizon?
Olga Golubnitschaja, Kristina Yeghiazaryan, +5 authors, Hans H Schild.
EPMA J, 2013 Feb 20; 4(1). PMID: 23418957    Free PMC article.
PAM50 proliferation score as a predictor of weekly paclitaxel benefit in breast cancer.
Miguel Martín, Aleix Prat, +24 authors, Philip S Bernard.
Breast Cancer Res Treat, 2013 Feb 21; 138(2). PMID: 23423445    Free PMC article.
Interpreting personal transcriptomes: personalized mechanism-scale profiling of RNA-seq data.
Alan Perez-Rathke, Haiquan Li, Yves A Lussier.
Pac Symp Biocomput, 2013 Feb 21;. PMID: 23424121    Free PMC article.
Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval.
C L Avery, C M Sitlani, +51 authors, B M Psaty.
Pharmacogenomics J, 2013 Mar 06; 14(1). PMID: 23459443    Free PMC article.
Molecular staging of node negative patients with colorectal cancer.
Terry Hyslop, Scott A Waldman.
J Cancer, 2013 Mar 06; 4(3). PMID: 23459453    Free PMC article.
Cultivating cohort studies for observational translational research.
David F Ransohoff.
Cancer Epidemiol Biomarkers Prev, 2013 Mar 07; 22(4). PMID: 23462919    Free PMC article.
Biomolecular events in cancer revealed by attractor metagenes.
Wei-Yi Cheng, Tai-Hsien Ou Yang, Dimitris Anastassiou.
PLoS Comput Biol, 2013 Mar 08; 9(2). PMID: 23468608    Free PMC article.
The CIN4 chromosomal instability qPCR classifier defines tumor aneuploidy and stratifies outcome in grade 2 breast cancer.
Attila Marcell Szász, Qiyuan Li, +10 authors, Janina Kulka.
PLoS One, 2013 Mar 08; 8(2). PMID: 23468873    Free PMC article.
Genomic signatures of pregnancy-associated breast cancer epithelia and stroma and their regulation by estrogens and progesterone.
Djuana M E Harvell, Jihye Kim, +5 authors, Kathryn B Horwitz.
Horm Cancer, 2013 Mar 13; 4(3). PMID: 23479404    Free PMC article.
A targeted RNAi screen of the breast cancer genome identifies KIF14 and TLN1 as genes that modulate docetaxel chemosensitivity in triple-negative breast cancer.
Stina Mui Singel, Crystal Cornelius, +4 authors, Jerry W Shay.
Clin Cancer Res, 2013 Mar 13; 19(8). PMID: 23479679    Free PMC article.
Overexpression of MACC1 and Its significance in human Breast Cancer Progression.
Yongbo Huang, Huizhong Zhang, +5 authors, Mengfeng Li.
Cell Biosci, 2013 Mar 19; 3(1). PMID: 23497677    Free PMC article.
Prediction of the Oncotype DX recurrence score: use of pathology-generated equations derived by linear regression analysis.
Molly E Klein, David J Dabbs, +4 authors, Rohit Bhargava.
Mod Pathol, 2013 Mar 19; 26(5). PMID: 23503643    Free PMC article.
Druggable protein interaction sites are more predisposed to surface pocket formation than the rest of the protein surface.
David K Johnson, John Karanicolas.
PLoS Comput Biol, 2013 Mar 19; 9(3). PMID: 23505360    Free PMC article.
Comparison of EndoPredict and Oncotype DX test results in hormone receptor positive invasive breast cancer.
Zsuzsanna Varga, Peter Sinn, +6 authors, Holger Moch.
PLoS One, 2013 Mar 19; 8(3). PMID: 23505515    Free PMC article.
Biomarkers of residual disease, disseminated tumor cells, and metastases in the MMTV-PyMT breast cancer model.
Christian Franci, Jenny Zhou, +4 authors, Hosein Kouros-Mehr.
PLoS One, 2013 Mar 23; 8(3). PMID: 23520493    Free PMC article.
Long-term prognostic performance of Ki67 rate in early stage, pT1-pT2, pN0, invasive breast carcinoma.
Fabien Reyal, David Hajage, +14 authors, Xavier Sastre-Garau.
PLoS One, 2013 Mar 26; 8(3). PMID: 23526930    Free PMC article.
Biologic determinants of tumor recurrence in stage II colon cancer: validation study of the 12-gene recurrence score in cancer and leukemia group B (CALGB) 9581.
Alan P Venook, Donna Niedzwiecki, +12 authors, Monica M Bertagnolli.
J Clin Oncol, 2013 Mar 27; 31(14). PMID: 23530100    Free PMC article.
Development and validation of a 32-gene prognostic index for prostate cancer progression.
Chin-Lee Wu, Brock E Schroeder, +8 authors, W Scott McDougal.
Proc Natl Acad Sci U S A, 2013 Mar 28; 110(15). PMID: 23533275    Free PMC article.
Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways.
Margit L H Riis, Xi Zhao, +6 authors, Vessela N Kristensen.
ISRN Oncol, 2013 Mar 28; 2013. PMID: 23533813    Free PMC article.
Molecular profiling of multiple human cancers defines an inflammatory cancer-associated molecular pattern and uncovers KPNA2 as a uniform poor prognostic cancer marker.
Saleh M Rachidi, Tingting Qin, +2 authors, Zihai Li.
PLoS One, 2013 Mar 29; 8(3). PMID: 23536776    Free PMC article.
Monitoring apoptosis and Bcl-2 on circulating tumor cells in patients with metastatic breast cancer.
Jeffrey B Smerage, G Thomas Budd, +9 authors, Daniel F Hayes.
Mol Oncol, 2013 Mar 30; 7(3). PMID: 23538216    Free PMC article.
Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer.
Patrick C O Leary, Sarah A Penny, +12 authors, William M Gallagher.
BMC Cancer, 2013 Apr 04; 13. PMID: 23547718    Free PMC article.
The combination of Ki67, histological grade and estrogen receptor status identifies a low-risk group among 1,854 chemo-naïve women with N0/N1 primary breast cancer.
Carina Strand, Martin Bak, +13 authors, Mårten Fernö.
Springerplus, 2013 Apr 06; 2(1). PMID: 23560250    Free PMC article.
Development of a miR-26 companion diagnostic test for adjuvant interferon-alpha therapy in hepatocellular carcinoma.
Junfang Ji, Lei Yu, +12 authors, Xin Wei Wang.
Int J Biol Sci, 2013 Apr 10; 9(3). PMID: 23569435    Free PMC article.
Gene expression profiling in breast cancer.
Belisario A Arango, Celine L Rivera, Stefan Glück.
Am J Transl Res, 2013 Apr 11; 5(2). PMID: 23573359    Free PMC article.
Molecular and therapeutic advances in the diagnosis and management of malignant pheochromocytomas and paragangliomas.
Aoife J Lowery, Siun Walsh, Enda W McDermott, Ruth S Prichard.
Oncologist, 2013 Apr 12; 18(4). PMID: 23576482    Free PMC article.
Development of a multi-biomarker disease activity test for rheumatoid arthritis.
Michael Centola, Guy Cavet, +14 authors, Jeffrey R Curtis.
PLoS One, 2013 Apr 16; 8(4). PMID: 23585841    Free PMC article.
Building a personalized medicine infrastructure at a major cancer center.
Funda Meric-Bernstam, Carol Farhangfar, John Mendelsohn, Gordon B Mills.
J Clin Oncol, 2013 Apr 17; 31(15). PMID: 23589548    Free PMC article.
Prognostic microRNA/mRNA signature from the integrated analysis of patients with invasive breast cancer.
Stefano Volinia, Carlo M Croce.
Proc Natl Acad Sci U S A, 2013 Apr 17; 110(18). PMID: 23589849    Free PMC article.
Highly Cited.
Dissecting GRB7-mediated signals for proliferation and migration in HER2 overexpressing breast tumor cells: GTP-ase rules.
De Pradip, Mark Bouzyk, Nandini Dey, Brian Leyland-Jones.
Am J Cancer Res, 2013 Apr 18; 3(2). PMID: 23593540    Free PMC article.
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer.
Adam A Margolin, Erhan Bilal, +27 authors, Anne-Lise Børresen-Dale.
Sci Transl Med, 2013 Apr 19; 5(181). PMID: 23596205    Free PMC article.
Cytoplasmic HuR expression correlates with P-gp, HER-2 positivity, and poor outcome in breast cancer.
Zhongpeng Zhu, Baocheng Wang, +6 authors, Jun Wang.
Tumour Biol, 2013 Apr 23; 34(4). PMID: 23605320
Interactions between immunity, proliferation and molecular subtype in breast cancer prognosis.
Srikanth Nagalla, Jeff W Chou, +9 authors, Lance D Miller.
Genome Biol, 2013 Apr 27; 14(4). PMID: 23618380    Free PMC article.
Highly Cited.
A comprehensive analysis of Aurora A; transcript levels are the most reliable in association with proliferation and prognosis in breast cancer.
Satoko Yamamoto, Mutsuko Yamamoto-Ibusuki, +2 authors, Hirotaka Iwase.
BMC Cancer, 2013 May 01; 13. PMID: 23627634    Free PMC article.
Interpreting cancer biology: refining our therapeutic algorithm in breast cancer.
Gabriel Hortobágyi, Pierfranco Conte.
Oncologist, 2013 May 02; 18(4). PMID: 23633451    Free PMC article.
A multigene expression assay to predict local recurrence risk for ductal carcinoma in situ of the breast.
Lawrence J Solin, Robert Gray, +13 authors, Sunil Badve.
J Natl Cancer Inst, 2013 May 04; 105(10). PMID: 23641039    Free PMC article.
Highly Cited.
Identification and validation of a new set of five genes for prediction of risk in early breast cancer.
Giorgio Mustacchi, Maria Pia Sormani, +5 authors, Luca Morandi.
Int J Mol Sci, 2013 May 08; 14(5). PMID: 23648477    Free PMC article.
Multiple suboptimal solutions for prediction rules in gene expression data.
Osamu Komori, Mari Pritchard, Shinto Eguchi.
Comput Math Methods Med, 2013 May 11; 2013. PMID: 23662163    Free PMC article.
Improving breast cancer survival analysis through competition-based multidimensional modeling.
Erhan Bilal, Janusz Dutkowski, +21 authors, Adam A Margolin.
PLoS Comput Biol, 2013 May 15; 9(5). PMID: 23671412    Free PMC article.
Ki-67 is a prognostic parameter in breast cancer patients: results of a large population-based cohort of a cancer registry.
E C Inwald, M Klinkhammer-Schalke, +4 authors, O Ortmann.
Breast Cancer Res Treat, 2013 May 16; 139(2). PMID: 23674192    Free PMC article.
Highly Cited.
A simple and reproducible breast cancer prognostic test.
Luigi Marchionni, Bahman Afsari, Donald Geman, Jeffrey T Leek.
BMC Genomics, 2013 May 21; 14. PMID: 23682826    Free PMC article.
Genomic biomarkers for personalized medicine: development and validation in clinical studies.
Shigeyuki Matsui.
Comput Math Methods Med, 2013 May 22; 2013. PMID: 23690882    Free PMC article.
Biomarker modulation following short-term vorinostat in women with newly diagnosed primary breast cancer.
Vered Stearns, Lisa K Jacobs, +16 authors, Nancy E Davidson.
Clin Cancer Res, 2013 May 31; 19(14). PMID: 23719261    Free PMC article.
Multigene assays and molecular markers in breast cancer: systematic review of health economic analyses.
Roman Rouzier, Paolo Pronzato, +3 authors, William J Valentine.
Breast Cancer Res Treat, 2013 Jun 01; 139(3). PMID: 23722312    Free PMC article.
Systematic Review.
Fertility preservation in young females with non-gynaecologic malignancy: an emerging speciality.
C Smyth, I Robertson, +5 authors, K Barry.
Ir J Med Sci, 2013 Jun 07; 183(1). PMID: 23740204
Digital quantification of gene expression in sequential breast cancer biopsies reveals activation of an immune response.
Rinath M Jeselsohn, Lillian Werner, +11 authors, Steven E Come.
PLoS One, 2013 Jun 07; 8(5). PMID: 23741308    Free PMC article.
A panel of four cytokines predicts the prognosis of patients with malignant gliomas.
Yi Lin, Guozhen Zhang, +9 authors, Tao Jiang.
J Neurooncol, 2013 Jun 12; 114(2). PMID: 23748572
Integrative analysis of cancer-related signaling pathways.
Thomas Kessler, Hendrik Hache, Christoph Wierling.
Front Physiol, 2013 Jun 14; 4. PMID: 23760067    Free PMC article.
Association between genomic recurrence risk and well-being among breast cancer patients.
Valesca P Retèl, Catharina G M Groothuis-Oudshoorn, +3 authors, Wim H van Harten.
BMC Cancer, 2013 Jun 20; 13. PMID: 23777535    Free PMC article.
The impact of the 21-gene Recurrence Score assay on clinical decision-making in node-positive (up to 3 positive nodes) estrogen receptor-positive breast cancer patients.
Salomon M Stemmer, Shmuel H Klang, +7 authors, Nicky Lieberman.
Breast Cancer Res Treat, 2013 Jun 27; 140(1). PMID: 23801158    Free PMC article.
A multi-site feasibility study for personalized medicine in canines with osteosarcoma.
Noel R Monks, David M Cherba, +10 authors, Craig P Webb.
J Transl Med, 2013 Jul 03; 11. PMID: 23815880    Free PMC article.
Interrogating differences in expression of targeted gene sets to predict breast cancer outcome.
Sarah A Andres, Guy N Brock, James L Wittliff.
BMC Cancer, 2013 Jul 04; 13. PMID: 23819905    Free PMC article.
Curation-free biomodules mechanisms in prostate cancer predict recurrent disease.
James L Chen, Alexander Hsu, +5 authors, Yves A Lussier.
BMC Med Genomics, 2013 Jul 17; 6 Suppl 2. PMID: 23819917    Free PMC article.
BreastMark: an integrated approach to mining publicly available transcriptomic datasets relating to breast cancer outcome.
Stephen F Madden, Colin Clarke, +5 authors, William M Gallagher.
Breast Cancer Res, 2013 Jul 04; 15(4). PMID: 23820017    Free PMC article.
Highly Cited.
Evaluation of a high-throughput, microfluidics platform for performing TaqMan™ qPCR using formalin-fixed paraffin-embedded tumors.
Ping Li, Elena Grigorenko, +3 authors, Hyung L Kim.
Bioanalysis, 2013 Jul 05; 5(13). PMID: 23822126    Free PMC article.
Serine, glycine and one-carbon units: cancer metabolism in full circle.
Jason W Locasale.
Nat Rev Cancer, 2013 Jul 05; 13(8). PMID: 23822983    Free PMC article.
Highly Cited. Review.
The EndoPredict Gene-Expression Assay in Clinical Practice - Performance and Impact on Clinical Decisions.
Berit Maria Müller, Elke Keil, +16 authors, Carsten Denkert.
PLoS One, 2013 Jul 05; 8(6). PMID: 23826382    Free PMC article.
Metasignatures identify two major subtypes of breast cancer.
Q Duan, Y Kou, +2 authors, A Ma'ayan.
CPT Pharmacometrics Syst Pharmacol, 2013 Jul 10; 2. PMID: 23836026    Free PMC article.
Liquid biopsy: monitoring cancer-genetics in the blood.
Emily Crowley, Federica Di Nicolantonio, Fotios Loupakis, Alberto Bardelli.
Nat Rev Clin Oncol, 2013 Jul 10; 10(8). PMID: 23836314
Highly Cited. Review.
The DREAM complex: master coordinator of cell cycle-dependent gene expression.
Subhashini Sadasivam, James A DeCaprio.
Nat Rev Cancer, 2013 Jul 12; 13(8). PMID: 23842645    Free PMC article.
Highly Cited. Review.
An integrative framework for Bayesian variable selection with informative priors for identifying genes and pathways.
Bin Peng, Dianwen Zhu, +4 authors, Xiaowei Yang.
PLoS One, 2013 Jul 12; 8(7). PMID: 23844055    Free PMC article.
Using large-scale molecular data sets to improve breast cancer treatment.
Chad J Creighton.
Breast Cancer Manag, 2012 May 01; 1(1). PMID: 23869198    Free PMC article.
Genes dysregulated to different extent or oppositely in estrogen receptor-positive and estrogen receptor-negative breast cancers.
Xianxiao Zhou, Tongwei Shi, +6 authors, Zheng Guo.
PLoS One, 2013 Jul 23; 8(7). PMID: 23875016    Free PMC article.
High-throughput identification of reference genes for research and clinical RT-qPCR analysis of breast cancer samples.
Diana V Maltseva, Nadezda A Khaustova, +6 authors, Alexander G Tonevitsky.
J Clin Bioinforma, 2013 Jul 24; 3(1). PMID: 23876162    Free PMC article.
MYBL2 is a sub-haploinsufficient tumor suppressor gene in myeloid malignancy.
Stefan Heinrichs, Lillian F Conover, +9 authors, A Thomas Look.
Elife, 2013 Jul 24; 2. PMID: 23878725    Free PMC article.
Cellular iron metabolism in prognosis and therapy of breast cancer.
Suzy V Torti, Frank M Torti.
Crit Rev Oncog, 2013 Jul 25; 18(5). PMID: 23879588    Free PMC article.
Luminal breast cancer: from biology to treatment.
Michail Ignatiadis, Christos Sotiriou.
Nat Rev Clin Oncol, 2013 Jul 25; 10(9). PMID: 23881035
Breast cancer metastasis: issues for the personalization of its prevention and treatment.
Natascia Marino, Stephan Woditschka, +4 authors, Patricia S Steeg.
Am J Pathol, 2013 Jul 31; 183(4). PMID: 23895915    Free PMC article.
Who gets genomic testing for breast cancer recurrence risk?
J T DeFrank, T Salz, K Reeder-Hayes, N T Brewer.
Public Health Genomics, 2013 Aug 01; 16(5). PMID: 23899493    Free PMC article.
The genomic map of breast cancer: which roads lead to better targeted therapies?
Justin M Balko, Thomas P Stricker, Carlos L Arteaga.
Breast Cancer Res, 2013 Aug 03; 15(4). PMID: 23905624    Free PMC article.
A gene signature for late distant metastasis in breast cancer identifies a potential mechanism of late recurrences.
Lorenza Mittempergher, Mahasti Saghatchian, +9 authors, Laura J van't Veer.
Mol Oncol, 2013 Aug 06; 7(5). PMID: 23910573    Free PMC article.
Estrogen receptor splice variants as a potential source of false-positive estrogen receptor status in breast cancer diagnostics.
Floris H Groenendijk, Wilbert Zwart, +2 authors, Rene Bernards.
Breast Cancer Res Treat, 2013 Aug 06; 140(3). PMID: 23912957    Free PMC article.
[Gene expression analysis in breast cancer. A new diagnostic tool in pathology].
C Denkert.
Pathologe, 2013 Aug 13; 34(5). PMID: 23934410
Evaluating use characteristics for the oncotype dx 21-gene recurrence score and concordance with chemotherapy use in early-stage breast cancer.
Clara Chen, Rahul Dhanda, +2 authors, Debra A Patt.
J Oncol Pract, 2013 Aug 15; 9(4). PMID: 23942918    Free PMC article.
A Tumor initiating cell-enriched prognostic signature for HER2+:ERα- breast cancer; rationale, new features, controversies and future directions.
Jeff C Liu, Sean E Egan, Eldad Zacksenhaus.
Oncotarget, 2013 Aug 16; 4(8). PMID: 23945331    Free PMC article.
Identification and validation of a multigene predictor of recurrence in primary laryngeal cancer.
Elena Fountzilas, Vassiliki Kotoula, +8 authors, George Fountzilas.
PLoS One, 2013 Aug 21; 8(8). PMID: 23950933    Free PMC article.
Preoperative core needle biopsy is accurate in determining molecular subtypes in invasive breast cancer.
Xiaosong Chen, Long Sun, +10 authors, Kunwei Shen.
BMC Cancer, 2013 Aug 21; 13. PMID: 23957561    Free PMC article.
The impact of the Oncotype Dx breast cancer assay in clinical practice: a systematic review and meta-analysis.
Josh J Carlson, Joshua A Roth.
Breast Cancer Res Treat, 2013 Aug 27; 141(1). PMID: 23974828    Free PMC article.
Highly Cited. Systematic Review.
Grading breast cancer tissues using molecular portraits.
Niclas Olsson, Petter Carlsson, +7 authors, Carl A K Borrebaeck.
Mol Cell Proteomics, 2013 Aug 29; 12(12). PMID: 23982162    Free PMC article.
Genomic Grade Index (GGI): feasibility in routine practice and impact on treatment decisions in early breast cancer.
Otto Metzger-Filho, Aurélie Catteau, +21 authors, Christos Sotiriou.
PLoS One, 2013 Aug 31; 8(8). PMID: 23990869    Free PMC article.
Molecular and cellular heterogeneity in breast cancer: challenges for personalized medicine.
Ashley G Rivenbark, Siobhan M O'Connor, William B Coleman.
Am J Pathol, 2013 Sep 03; 183(4). PMID: 23993780    Free PMC article.
Development of omics-based clinical tests for prognosis and therapy selection: the challenge of achieving statistical robustness and clinical utility.
Lisa M McShane, Mei-Yin C Polley.
Clin Trials, 2013 Sep 04; 10(5). PMID: 24000377    Free PMC article.
Identification of upstream regulators for prognostic expression signature genes in colorectal cancer.
Taejeong Bae, Kyoohyoung Rho, +3 authors, Sunghoon Kim.
BMC Syst Biol, 2013 Sep 07; 7. PMID: 24006872    Free PMC article.
Effect of chemotherapy for luminal a breast cancer.
Naotaka Uchida, Takako Suda, Kiyosuke Ishiguro.
Yonago Acta Med, 2013 Sep 14; 56(2). PMID: 24031152    Free PMC article.
Prediction of late distant recurrence in patients with oestrogen-receptor-positive breast cancer: a prospective comparison of the breast-cancer index (BCI) assay, 21-gene recurrence score, and IHC4 in the TransATAC study population.
Dennis C Sgroi, Ivana Sestak, +9 authors, Mitch Dowsett.
Lancet Oncol, 2013 Sep 17; 14(11). PMID: 24035531    Free PMC article.
Highly Cited.
Integration of cancer genomics with treatment selection: from the genome to predictive biomarkers.
Thomas J Ow, Vlad C Sandulache, Heath D Skinner, Jeffrey N Myers.
Cancer, 2013 Sep 17; 119(22). PMID: 24037788    Free PMC article.
Genome-wide signatures of transcription factor activity: connecting transcription factors, disease, and small molecules.
Jing Chen, Zhen Hu, +4 authors, Mario Medvedovic.
PLoS Comput Biol, 2013 Sep 17; 9(9). PMID: 24039560    Free PMC article.
Exosome derived from epigallocatechin gallate treated breast cancer cells suppresses tumor growth by inhibiting tumor-associated macrophage infiltration and M2 polarization.
Ji-Young Jang, Jong-Kuen Lee, Yoon-Kyung Jeon, Chul-Woo Kim.
BMC Cancer, 2013 Sep 21; 13. PMID: 24044575    Free PMC article.
Validation of a proliferation-based expression signature as prognostic marker in early stage lung adenocarcinoma.
Ignacio I Wistuba, Carmen Behrens, +16 authors, Edward S Kim.
Clin Cancer Res, 2013 Sep 21; 19(22). PMID: 24048333    Free PMC article.
Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers.
Giampaolo Bianchini, Lajos Pusztai, +16 authors, Luca Gianni.
Breast Cancer Res, 2013 Sep 26; 15(5). PMID: 24060333    Free PMC article.
SurvExpress: an online biomarker validation tool and database for cancer gene expression data using survival analysis.
Raul Aguirre-Gamboa, Hugo Gomez-Rueda, +5 authors, Victor Treviño.
PLoS One, 2013 Sep 26; 8(9). PMID: 24066126    Free PMC article.
Highly Cited.
The molecular diversity of Luminal A breast tumors.
Giovanni Ciriello, Rileen Sinha, +5 authors, Nikolaus Schultz.
Breast Cancer Res Treat, 2013 Oct 08; 141(3). PMID: 24096568    Free PMC article.
18F-FDG uptake in breast cancer correlates with immunohistochemically defined subtypes.
Hye Ryoung Koo, Jeong Seon Park, +9 authors, Woo Kyung Moon.
Eur Radiol, 2013 Oct 08; 24(3). PMID: 24097303
Concurrent gene signatures for han chinese breast cancers.
Chi-Cheng Huang, Shih-Hsin Tu, +5 authors, Eric Y Chuang.
PLoS One, 2013 Oct 08; 8(10). PMID: 24098497    Free PMC article.
Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection.
Trine Tramm, Guido Hennig, +5 authors, Jens Overgaard.
Virchows Arch, 2013 Oct 09; 463(6). PMID: 24100522
Evaluating the 21-gene assay Recurrence Score® as a predictor of clinical response to 24 weeks of neoadjuvant exemestane in estrogen receptor-positive breast cancer.
Takayuki Ueno, Norikazu Masuda, +12 authors, Masakazu Toi.
Int J Clin Oncol, 2013 Oct 09; 19(4). PMID: 24101215
Analytical validation of the Oncotype DX prostate cancer assay - a clinical RT-PCR assay optimized for prostate needle biopsies.
Dejan Knezevic, Audrey D Goddard, +8 authors, Christopher Quale.
BMC Genomics, 2013 Oct 10; 14. PMID: 24103217    Free PMC article.
Highly Cited.
A robust prognostic signature for hormone-positive node-negative breast cancer.
Obi L Griffith, François Pepin, +4 authors, Joe W Gray.
Genome Med, 2013 Oct 12; 5(10). PMID: 24112773    Free PMC article.
Multiplatform single-sample estimates of transcriptional activation.
Stephen R Piccolo, Michelle R Withers, +2 authors, W Evan Johnson.
Proc Natl Acad Sci U S A, 2013 Oct 17; 110(44). PMID: 24128763    Free PMC article.
Genomics: Comparisons across cancers.
Alan Ashworth, Thomas J Hudson.
Nature, 2013 Oct 18; 502(7471). PMID: 24132284
Benefit risk assessment and update on the use of docetaxel in the management of breast cancer.
Scheryll Alken, Catherine M Kelly.
Cancer Manag Res, 2013 Oct 22; 5. PMID: 24143122    Free PMC article.
Genomic instability: a stronger prognostic marker than proliferation for early stage luminal breast carcinomas.
Anne Vincent-Salomon, Vanessa Benhamo, +13 authors, Olivier Delattre.
PLoS One, 2013 Oct 22; 8(10). PMID: 24143191    Free PMC article.
Prognostic value of the nodal ratio and ki-67 expression in breast cancer patients treated with postmastectomy radiotherapy.
Tae Ryool Koo, Keun Yong Eom, +5 authors, In Ah Kim.
J Breast Cancer, 2013 Oct 25; 16(3). PMID: 24155756    Free PMC article.
Molecular diagnosis for personalized target therapy in gastric cancer.
Jae Yong Cho.
J Gastric Cancer, 2013 Oct 25; 13(3). PMID: 24156032    Free PMC article.
The EndoPredict score provides prognostic information on late distant metastases in ER+/HER2- breast cancer patients.
P Dubsky, J C Brase, +18 authors, Austrian Breast and Colorectal Cancer Study Group (ABCSG).
Br J Cancer, 2013 Oct 26; 109(12). PMID: 24157828    Free PMC article.
Highly Cited.
Plasma proteomics analysis of tamoxifen resistance in breast cancer.
Keivan Majidzadeh-A, Javad Gharechahi.
Med Oncol, 2013 Oct 26; 30(4). PMID: 24158757
PROGgene: gene expression based survival analysis web application for multiple cancers.
Chirayu Pankaj Goswami, Harikrishna Nakshatri.
J Clin Bioinforma, 2013 Oct 30; 3(1). PMID: 24165311    Free PMC article.
Highly Cited.
An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk.
Christina Yau, John Sninsky, +9 authors, Christopher C Benz.
Breast Cancer Res, 2013 Nov 01; 15(5). PMID: 24172169    Free PMC article.
In situ Protein Detection for Companion Diagnostics.
Gabriela Gremel, Karin Grannas, +2 authors, Agata Zieba.
Front Oncol, 2013 Nov 08; 3. PMID: 24199171    Free PMC article.
A collagen-remodeling gene signature regulated by TGF-β signaling is associated with metastasis and poor survival in serous ovarian cancer.
Dong-Joo Cheon, Yunguang Tong, +9 authors, Sandra Orsulic.
Clin Cancer Res, 2013 Nov 13; 20(3). PMID: 24218511    Free PMC article.
Highly Cited.
Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration.
Lisa M McShane, Margaret M Cavenagh, +12 authors, Barbara A Conley.
BMC Med, 2013 Nov 16; 11. PMID: 24228635    Free PMC article.
Molecular profiling for breast cancer: a comprehensive review.
Muaiad Kittaneh, Alberto J Montero, Stefan Glück.
Biomark Cancer, 2013 Nov 20; 5. PMID: 24250234    Free PMC article.
An unmet need: tailoring extended adjuvant endocrine therapy.
G Bianchini, L Gianni.
Br J Cancer, 2013 Nov 21; 109(12). PMID: 24253504    Free PMC article.
Construction and analysis of multiparameter prognostic models for melanoma outcome.
Bonnie E Gould Rothberg, David L Rimm.
Methods Mol Biol, 2013 Nov 22; 1102. PMID: 24258982    Free PMC article.
Systematic Review.
Predicting degree of benefit from adjuvant trastuzumab in NSABP trial B-31.
Katherine L Pogue-Geile, Chungyeul Kim, +26 authors, Soonmyung Paik.
J Natl Cancer Inst, 2013 Nov 23; 105(23). PMID: 24262440    Free PMC article.
Two-gene expression ratio as predictor for breast cancer treated with tamoxifen: evidence from meta-analysis.
Lin Zhao, Shimiao Zhu, Ying Gao, Yaogang Wang.
Tumour Biol, 2013 Nov 23; 35(4). PMID: 24264313
Prognostic factors in elderly patients with breast cancer.
Alessandro Cappellani, Maria Di Vita, +5 authors, Massimiliano Berretta.
BMC Surg, 2013 Dec 07; 13 Suppl 2. PMID: 24268048    Free PMC article.
Correlation between ER, PR, HER-2, Bcl-2, p53, proliferative and apoptotic indexes with HER-2 gene amplification and TOP2A gene amplification and deletion in four molecular subtypes of breast cancer.
Olivera Mitrović, Vladan Čokić, +6 authors, Snežana Furtula.
Target Oncol, 2013 Nov 26; 9(4). PMID: 24272208
Biomarker enrichment strategies: matching trial design to biomarker credentials.
Boris Freidlin, Edward L Korn.
Nat Rev Clin Oncol, 2013 Nov 28; 11(2). PMID: 24281059
Biomarkers for Basal-like Breast Cancer.
Jennifer R Choo, Torsten O Nielsen.
Cancers (Basel), 2010 Jan 01; 2(2). PMID: 24281106    Free PMC article.
MicroRNAs and triple negative breast cancer.
Elvira D'Ippolito, Marilena V Iorio.
Int J Mol Sci, 2013 Nov 29; 14(11). PMID: 24284394    Free PMC article.
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.
Suzanne A Eccles, Eric O Aboagye, +84 authors, Alastair M Thompson.
Breast Cancer Res, 2013 Nov 30; 15(5). PMID: 24286369    Free PMC article.
Highly Cited. Review.
Cost effectiveness of a 21-gene recurrence score assay versus Canadian clinical practice in post-menopausal women with early-stage estrogen or progesterone-receptor-positive, axillary lymph-node positive breast cancer.
Malek B Hannouf, Bin Xie, Muriel Brackstone, Gregory S Zaric.
Pharmacoeconomics, 2013 Nov 30; 32(2). PMID: 24288208
Gene expression profiles of inflammatory breast cancer: correlation with response to neoadjuvant chemotherapy and metastasis-free survival.
F Bertucci, N T Ueno, +16 authors, S J Van Laere.
Ann Oncol, 2013 Dec 05; 25(2). PMID: 24299959    Free PMC article.
Prognostic discrimination using a 70-gene signature among patients with estrogen receptor-positive breast cancer and an intermediate 21-gene recurrence score.
Sung Gwe Ahn, Hak Min Lee, +5 authors, In-Sun Chu.
Int J Mol Sci, 2013 Dec 07; 14(12). PMID: 24304542    Free PMC article.
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.
Atsushi Terunuma, Nagireddy Putluri, +31 authors, Stefan Ambs.
J Clin Invest, 2013 Dec 10; 124(1). PMID: 24316975    Free PMC article.
Highly Cited.
Pathway analyses and understanding disease associations.
Yu Liu, Mark R Chance.
Curr Genet Med Rep, 2013 Dec 10; 1(4). PMID: 24319650    Free PMC article.
The prognostic value of mitotic activity index (MAI), phosphohistone H3 (PPH3), cyclin B1, cyclin A, and Ki67, alone and in combinations, in node-negative premenopausal breast cancer.
Marie Klintman, Carina Strand, +11 authors, Mårten Fernö.
PLoS One, 2013 Dec 11; 8(12). PMID: 24324728    Free PMC article.
A prognostic gene signature for metastasis-free survival of triple negative breast cancer patients.
Unjin Lee, Casey Frankenberger, +6 authors, Marsha Rich Rosner.
PLoS One, 2013 Dec 19; 8(12). PMID: 24349199    Free PMC article.
Magnetic resonance metabolic profiling of breast cancer tissue obtained with core needle biopsy for predicting pathologic response to neoadjuvant chemotherapy.
Ji Soo Choi, Hyeon-Man Baek, +5 authors, Youn Ki Nam.
PLoS One, 2013 Dec 25; 8(12). PMID: 24367616    Free PMC article.
The impact of the Oncotype DX Recurrence Score on treatment decisions and clinical outcomes in patients with early breast cancer: the Maccabi Healthcare Services experience with a unified testing policy.
Nava Siegelmann-Danieli, Barbara Silverman, +3 authors, Avi Porath.
Ecancermedicalscience, 2014 Jan 05; 7. PMID: 24386009    Free PMC article.
Expression profiling of cervical cancers in Indian women at different stages to identify gene signatures during progression of the disease.
Asha Thomas, Umesh Mahantshetty, +4 authors, Rita Mulherkar.
Cancer Med, 2014 Jan 10; 2(6). PMID: 24403257    Free PMC article.
Overview of diagnostic/targeted treatment combinations in personalized medicine for breast cancer patients.
Anna Tessari, Dario Palmieri, Serena Di Cosimo.
Pharmgenomics Pers Med, 2014 Jan 10; 7. PMID: 24403841    Free PMC article.
Neoadjuvant Hormonal Therapy is Associated with Comparable Outcomes to Neoadjuvant Chemotherapy in Post-Menopausal Women with Estrogen Receptor-Positive Breast Cancer.
David M Marcus, Jeffrey M Switchenko, +5 authors, Mylin A Torres.
Front Oncol, 2014 Jan 11; 3. PMID: 24409418    Free PMC article.
Comparison of study designs used to detect and characterize pharmacogenomic interactions in nonexperimental studies: a simulation study.
Christy L Avery, Jane S Der, Eric A Whitsel, Til Stürmer.
Pharmacogenet Genomics, 2014 Jan 15; 24(3). PMID: 24413365    Free PMC article.
AGO Recommendations for Diagnosis and Treatment of Patients with Early Breast Cancer: Update 2013.
Anton Scharl, Christoph Thomssen, Nadia Harbeck, Volkmar Müller.
Breast Care (Basel), 2014 Jan 15; 8(3). PMID: 24415966    Free PMC article.
Breast Cancer Biomarkers: Utility in Clinical Practice.
Fanny Le Du, Naoto T Ueno, Ana M Gonzalez-Angulo.
Curr Breast Cancer Rep, 2014 Jan 15; 5(4). PMID: 24416469    Free PMC article.
Reply to E.J. Moylan et al.
Sandra M Swain, Gong Tang, Charles E Geyer.
J Clin Oncol, 2014 Jan 15; 32(6). PMID: 24419136    Free PMC article.
Galectin-3 disruption impaired tumoral angiogenesis by reducing VEGF secretion from TGFβ1-induced macrophages.
Camila Maria Longo Machado, Luciana Nogueira Sousa Andrade, +8 authors, Roger Chammas.
Cancer Med, 2014 Jan 15; 3(2). PMID: 24421272    Free PMC article.
Timing of determining axillary lymph node status when neoadjuvant chemotherapy is used.
Eleftherios P Mamounas.
Curr Oncol Rep, 2014 Jan 22; 16(2). PMID: 24445496    Free PMC article.
Oncotype dx results in multiple primary breast cancers.
Michael J Toole, Kelley M Kidwell, Catherine Van Poznak.
Breast Cancer (Auckl), 2014 Jan 24; 8. PMID: 24453493    Free PMC article.
Validation of proposed prostate cancer biomarkers with gene expression data: a long road to travel.
Adriana Amaro, Alessia Isabella Esposito, +4 authors, Ulrich Pfeffer.
Cancer Metastasis Rev, 2014 Jan 31; 33(2-3). PMID: 24477410    Free PMC article.
Molecular tests as prognostic factors in breast cancer.
Marc J van de Vijver.
Virchows Arch, 2014 Feb 04; 464(3). PMID: 24487789
Regularized Multivariate Regression for Identifying Master Predictors with Application to Integrative Genomics Study of Breast Cancer.
Jie Peng, Ji Zhu, +4 authors, Pei Wang.
Ann Appl Stat, 2010 Mar 01; 4(1). PMID: 24489618    Free PMC article.
Accurate data processing improves the reliability of Affymetrix gene expression profiles from FFPE samples.
Maurizio Callari, Antonio Lembo, +5 authors, Paolo Provero.
PLoS One, 2014 Feb 04; 9(1). PMID: 24489733    Free PMC article.
Breast tumor subgroups reveal diverse clinical prognostic power.
Zhaoqi Liu, Xiang-Sun Zhang, Shihua Zhang.
Sci Rep, 2014 Feb 07; 4. PMID: 24499868    Free PMC article.
Development and validation of a gene expression score that predicts response to fulvestrant in breast cancer patients.
Steen Knudsen, Thomas Jensen, +5 authors, Elizabeth Anderson.
PLoS One, 2014 Feb 08; 9(2). PMID: 24505287    Free PMC article.
Links between oestrogen receptor activation and proteolysis: relevance to hormone-regulated cancer therapy.
Wen Zhou, Joyce M Slingerland.
Nat Rev Cancer, 2014 Feb 08; 14(1). PMID: 24505618
Gene co-expression modules as clinically relevant hallmarks of breast cancer diversity.
Denise M Wolf, Marc E Lenburg, +2 authors, Laura J van 't Veer.
PLoS One, 2014 Feb 12; 9(2). PMID: 24516633    Free PMC article.
Intrinsic subtypes from the PAM50 gene expression assay in a population-based breast cancer survivor cohort: prognostication of short- and long-term outcomes.
Bette J Caan, Carol Sweeney, +8 authors, Philip S Bernard.
Cancer Epidemiol Biomarkers Prev, 2014 Feb 14; 23(5). PMID: 24521998    Free PMC article.
Radiation-induced gene signature predicts pathologic complete response to neoadjuvant chemotherapy in breast cancer patients.
Daniel S Oh, Maggie C U Cheang, Cheng Fan, Charles M Perou.
Radiat Res, 2014 Feb 18; 181(2). PMID: 24527691    Free PMC article.
Genomic profiling in luminal breast cancer.
Oleg Gluz, Daniel Hofmann, +3 authors, Nadia Harbeck.
Breast Care (Basel), 2014 Feb 20; 8(6). PMID: 24550749    Free PMC article.
Which threshold for ER positivity? a retrospective study based on 9639 patients.
M Yi, L Huo, +11 authors, K K Hunt.
Ann Oncol, 2014 Feb 25; 25(5). PMID: 24562447    Free PMC article.
A Majority of Low (1-10%) ER Positive Breast Cancers Behave Like Hormone Receptor Negative Tumors.
Jyothi S Prabhu, Aruna Korlimarla, +12 authors, T S Sridhar.
J Cancer, 2014 Feb 25; 5(2). PMID: 24563670    Free PMC article.
Treatment decisions in estrogen receptor-positive early breast cancer patients with intermediate oncotype DX recurrence score results.
Georgeta Fried, Mor Moskovitz.
Springerplus, 2014 Feb 26; 3. PMID: 24567880    Free PMC article.
Personalized medicine: risk prediction, targeted therapies and mobile health technology.
Daniel F Hayes, Hugh S Markus, R David Leslie, Eric J Topol.
BMC Med, 2014 Mar 04; 12. PMID: 24580858    Free PMC article.
Identification of a 251 gene expression signature that can accurately detect M. tuberculosis in patients with and without HIV co-infection.
Noor Dawany, Louise C Showe, +7 authors, Luis J Montaner.
PLoS One, 2014 Mar 04; 9(2). PMID: 24587128    Free PMC article.
Gene expression analysis in RA: towards personalized medicine.
A N Burska, K Roget, +8 authors, F Ponchel.
Pharmacogenomics J, 2014 Mar 05; 14(2). PMID: 24589910    Free PMC article.
Prognostic value of gene signatures and proliferation in lymph-node-negative breast cancer.
Kristin Jonsdottir, Jörg Assmus, +4 authors, Emiel A M Janssen.
PLoS One, 2014 Mar 07; 9(3). PMID: 24599057    Free PMC article.
Novel combination markers for predicting survival in patients with muscle invasive bladder cancer: USP18 and DGCR2.
Ye-Hwan Kim, Won Tae Kim, +7 authors, Wun-Jae Kim.
J Korean Med Sci, 2014 Mar 13; 29(3). PMID: 24616583    Free PMC article.
Nottingham Prognostic Index Plus (NPI+): a modern clinical decision making tool in breast cancer.
E A Rakha, D Soria, +6 authors, I O Ellis.
Br J Cancer, 2014 Mar 13; 110(7). PMID: 24619074    Free PMC article.
CCNA2 is a prognostic biomarker for ER+ breast cancer and tamoxifen resistance.
Tian Gao, Yong Han, +3 authors, Jiafu Ji.
PLoS One, 2014 Mar 14; 9(3). PMID: 24622579    Free PMC article.
Analytical validation of the PAM50-based Prosigna Breast Cancer Prognostic Gene Signature Assay and nCounter Analysis System using formalin-fixed paraffin-embedded breast tumor specimens.
Torsten Nielsen, Brett Wallden, +7 authors, James Storhoff.
BMC Cancer, 2014 Mar 15; 14. PMID: 24625003    Free PMC article.
Highly Cited.
Multi-level gene expression signatures, but not binary, outperform Ki67 for the long term prognostication of breast cancer patients.
Nicholas P Tobin, Linda S Lindström, +3 authors, Kristian Wennmalm.
Mol Oncol, 2014 Mar 19; 8(3). PMID: 24630985    Free PMC article.
Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression.
Janna K Mouw, Yoshihiro Yui, +10 authors, Valerie M Weaver.
Nat Med, 2014 Mar 19; 20(4). PMID: 24633304    Free PMC article.
Highly Cited.
Inferring gene dependency network specific to phenotypic alteration based on gene expression data and clinical information of breast cancer.
Xionghui Zhou, Juan Liu.
PLoS One, 2014 Mar 19; 9(3). PMID: 24637666    Free PMC article.
A supervised network analysis on gene expression profiles of breast tumors predicts a 41-gene prognostic signature of the transcription factor MYB across molecular subtypes.
Li-Yu D Liu, Li-Yun Chang, +3 authors, Fon-Jou Hsieh.
Comput Math Methods Med, 2014 Mar 19; 2014. PMID: 24639887    Free PMC article.
Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status.
Xi Zhao, Einar Andreas Rødland, +5 authors, Anne-Lise Børresen-Dale.
BMC Cancer, 2014 Mar 22; 14. PMID: 24645668    Free PMC article.
Estrogen receptor-positive breast cancer molecular signatures and therapeutic potentials (Review).
Mei Hong Zhang, Hong Tao Man, +2 authors, Shi Liang Ma.
Biomed Rep, 2014 Mar 22; 2(1). PMID: 24649067    Free PMC article.
Collagen gel droplet-embedded culture-drug sensitivity test and Ki67 expression in estrogen receptor-positive and HER2-negative breast cancer.
Katsunori Tozuka, Jun Horiguchi, +7 authors, Izumi Takeyoshi.
Mol Clin Oncol, 2013 Jan 01; 1(1). PMID: 24649129    Free PMC article.
Evaluation and correlation of risk recurrence in early breast cancer assessed by Oncotype DX®, clinicopathological markers and tumor cell dissemination in the blood and bone marrow.
Bahriye Aktas, Agnes Bankfalvi, +2 authors, Sabine Kasimir-Bauer.
Mol Clin Oncol, 2014 Mar 22; 1(6). PMID: 24649291    Free PMC article.
Implications of functional proteomics in breast cancer.
Young Kwang Chae, Ana Maria Gonzalez-Angulo.
Oncologist, 2014 Mar 26; 19(4). PMID: 24664486    Free PMC article.
Adaptive designs for clinical trials assessing biomarker-guided treatment strategies.
J Wason, A Marshall, +2 authors, N Stallard.
Br J Cancer, 2014 Mar 29; 110(8). PMID: 24667651    Free PMC article.
A surprising cross-species conservation in the genomic landscape of mouse and human oral cancer identifies a transcriptional signature predicting metastatic disease.
Michael D Onken, Ashley E Winkler, +10 authors, Ravindra Uppaluri.
Clin Cancer Res, 2014 Mar 29; 20(11). PMID: 24668645    Free PMC article.
Clinical prediction rules in practice: review of clinical guidelines and survey of GPs.
Annette Plüddemann, Emma Wallace, +13 authors, Richard Stevens.
Br J Gen Pract, 2014 Apr 02; 64(621). PMID: 24686888    Free PMC article.
An approach to evaluating and comparing biomarkers for patient treatment selection.
Holly Janes, Marshall D Brown, Ying Huang, Margaret S Pepe.
Int J Biostat, 2014 Apr 04; 10(1). PMID: 24695044    Free PMC article.
Predictive performance of microarray gene signatures: impact of tumor heterogeneity and multiple mechanisms of drug resistance.
Charlotte K Y Ng, Britta Weigelt, +5 authors, Jorge S Reis-Filho.
Cancer Res, 2014 Apr 08; 74(11). PMID: 24706696    Free PMC article.
Next generation DNA sequencing and the future of genomic medicine.
Matthew W Anderson, Iris Schrijver.
Genes (Basel), 2010 Jan 01; 1(1). PMID: 24710010    Free PMC article.
Prospective multicenter study of the impact of oncotype DX colon cancer assay results on treatment recommendations in stage II colon cancer patients.
Geetika Srivastava, Lindsay A Renfro, +10 authors, Steven R Alberts.
Oncologist, 2014 Apr 09; 19(5). PMID: 24710310    Free PMC article.
Clinical validation of the EndoPredict test in node-positive, chemotherapy-treated ER+/HER2- breast cancer patients: results from the GEICAM 9906 trial.
Miguel Martin, Jan C Brase, +15 authors, Alvaro Rodriguez-Lescure.
Breast Cancer Res, 2014 Apr 15; 16(2). PMID: 24725534    Free PMC article.
Fusion transcript discovery in formalin-fixed paraffin-embedded human breast cancer tissues reveals a link to tumor progression.
Yan Ma, Ranjana Ambannavar, +10 authors, Kunbin Qu.
PLoS One, 2014 Apr 15; 9(4). PMID: 24727804    Free PMC article.
Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer.
F Al-Ejeh, P T Simpson, +12 authors, K K Khanna.
Oncogenesis, 2014 Apr 23; 3. PMID: 24752235    Free PMC article.
Principles and methods of integrative genomic analyses in cancer.
Vessela N Kristensen, Ole Christian Lingjærde, +3 authors, Anne-Lise Børresen-Dale.
Nat Rev Cancer, 2014 Apr 25; 14(5). PMID: 24759209
Highly Cited. Review.
JAK2 expression is associated with tumor-infiltrating lymphocytes and improved breast cancer outcomes: implications for evaluating JAK2 inhibitors.
Chris P Miller, Jason D Thorpe, +7 authors, C Anthony Blau.
Cancer Immunol Res, 2014 Apr 26; 2(4). PMID: 24764577    Free PMC article.
Patients' perceptions of gene expression profiling in breast cancer treatment decisions.
Y Bombard, L Rozmovits, +3 authors, D A Marshall.
Curr Oncol, 2014 Apr 26; 21(2). PMID: 24764705    Free PMC article.
Interdisciplinary GoR level III Guidelines for the Diagnosis, Therapy and Follow-up Care of Breast Cancer: Short version - AWMF Registry No.: 032-045OL AWMF-Register-Nummer: 032-045OL - Kurzversion 3.0, Juli 2012.
R Kreienberg, U-S Albert, +3 authors, A Wöckel.
Geburtshilfe Frauenheilkd, 2014 Apr 29; 73(6). PMID: 24771925    Free PMC article.
Multigene Assays for Classification, Prognosis, and Prediction in Breast Cancer: a Critical Review on the Background and Clinical Utility.
P Sinn, S Aulmann, +6 authors, A Schneeweiss.
Geburtshilfe Frauenheilkd, 2014 Apr 29; 73(9). PMID: 24771945    Free PMC article.
Activation of the PI3K/mTOR/AKT pathway and survival in solid tumors: systematic review and meta-analysis.
Alberto Ocana, Francisco Vera-Badillo, +7 authors, Eitan Amir.
PLoS One, 2014 Apr 30; 9(4). PMID: 24777052    Free PMC article.
Highly Cited. Systematic Review.
Impact of adjuvant chemotherapy on long-term employment of survivors of early-stage breast cancer.
Reshma Jagsi, Sarah T Hawley, +7 authors, Steven J Katz.
Cancer, 2014 Apr 30; 120(12). PMID: 24777606    Free PMC article.
Ten-gene biomarker panel: a new hope for ovarian cancer?
Dong-Joo Cheon, Sandra Orsulic.
Biomark Med, 2014 May 07; 8(4). PMID: 24796616    Free PMC article.
Multiplex quantitative measurement of mRNAs from fixed tissue microarray sections.
Michael Armani, Michael Tangrea, +9 authors, Stephen M Hewitt.
Appl Immunohistochem Mol Morphol, 2014 May 09; 22(5). PMID: 24809843    Free PMC article.
cDNA hybrid capture improves transcriptome analysis on low-input and archived samples.
Christopher R Cabanski, Vincent Magrini, +12 authors, Christopher A Maher.
J Mol Diagn, 2014 May 13; 16(4). PMID: 24814956    Free PMC article.
Use of mTOR inhibitors in the treatment of breast cancer: an evaluation of factors that influence patient outcomes.
Guy Jerusalem, Andree Rorive, Joelle Collignon.
Breast Cancer (Dove Med Press), 2014 May 17; 6. PMID: 24833916    Free PMC article.
Predictive and prognostic value of the 21-gene recurrence score in hormone receptor-positive, node-positive breast cancer.
Adam M Brufsky.
Am J Clin Oncol, 2014 May 24; 37(4). PMID: 24853663    Free PMC article.
Systematic Review.
GATA4 immunolocalization in breast carcinoma as a potent prognostic predictor.
Kiyoshi Takagi, Takashi Moriguchi, +6 authors, Takashi Suzuki.
Cancer Sci, 2014 May 28; 105(5). PMID: 24862985    Free PMC article.
Integration of mRNA expression profile, copy number alterations, and microRNA expression levels in breast cancer to improve grade definition.
Claudia Cava, Gloria Bertoli, +5 authors, Isabella Castiglioni.
PLoS One, 2014 May 29; 9(5). PMID: 24866763    Free PMC article.
Current status of gene expression profiling to assist decision making in stage II colon cancer.
Cheng E Chee, Neal J Meropol.
Oncologist, 2014 May 30; 19(7). PMID: 24869929    Free PMC article.
Systematic pathway enrichment analysis of a genome-wide association study on breast cancer survival reveals an influence of genes involved in cell adhesion and calcium signaling on the patients' clinical outcome.
Andrea Woltmann, Bowang Chen, +11 authors, Asta Försti.
PLoS One, 2014 Jun 03; 9(6). PMID: 24886783    Free PMC article.
Outcomes by tumor subtype and treatment pattern in women with small, node-negative breast cancer: a multi-institutional study.
Ines Vaz-Luis, Rebecca A Ottesen, +10 authors, Nancy U Lin.
J Clin Oncol, 2014 Jun 04; 32(20). PMID: 24888816    Free PMC article.
Combining biomarkers to optimize patient treatment recommendations.
Chaeryon Kang, Holly Janes, Ying Huang.
Biometrics, 2014 Jun 04; 70(3). PMID: 24889663    Free PMC article.
Aspirin intake and breast cancer survival - a nation-wide study using prospectively recorded data in Sweden.
Michelle D Holmes, Henrik Olsson, +6 authors, Karin Ekström Smedby.
BMC Cancer, 2014 Jun 04; 14. PMID: 24890520    Free PMC article.
Tumor microenvironment of metastasis and risk of distant metastasis of breast cancer.
Thomas E Rohan, Xiaonan Xue, +10 authors, Joan G Jones.
J Natl Cancer Inst, 2014 Jun 05; 106(8). PMID: 24895374    Free PMC article.
Highly Cited.
An 18-gene signature for vascular invasion is associated with aggressive features and reduced survival in breast cancer.
Monica Mannelqvist, Elisabeth Wik, Ingunn M Stefansson, Lars A Akslen.
PLoS One, 2014 Jun 07; 9(6). PMID: 24905342    Free PMC article.
A 41-gene signature derived from breast cancer stem cells as a predictor of survival.
Zhi-Qiang Yin, Jian-Jun Liu, +9 authors, Hong-Xia Wang.
J Exp Clin Cancer Res, 2014 Jun 08; 33. PMID: 24906694    Free PMC article.
Genetic-based prediction of disease traits: prediction is very difficult, especially about the future.
Steven J Schrodi, Shubhabrata Mukherjee, +11 authors, Daniel E Weeks.
Front Genet, 2014 Jun 12; 5. PMID: 24917882    Free PMC article.
Modern Risk Assessment for Individualizing Treatment Concepts in Early-stage Breast Cancer.
Alex Farr, Rachel Wuerstlein, +2 authors, Nadia Harbeck.
Rev Obstet Gynecol, 2013 Jan 01; 6(3-4). PMID: 24920978    Free PMC article.
Luminal breast cancer classification according to proliferative indices: clinicopathological characteristics and short-term survival analysis.
Yan Sun, Gang Nie, +3 authors, Haibo Wang.
Med Oncol, 2014 Jun 18; 31(7). PMID: 24935624
Access to personalized medicine: factors influencing the use and value of gene expression profiling in breast cancer treatment.
Y Bombard, L Rozmovits, +3 authors, D A Marshall.
Curr Oncol, 2014 Jun 19; 21(3). PMID: 24940102    Free PMC article.
Breast cancer prognosis risk estimation using integrated gene expression and clinical data.
Ashish Saini, Jingyu Hou, Wanlei Zhou.
Biomed Res Int, 2014 Jun 21; 2014. PMID: 24949450    Free PMC article.
Breast Cancer Survival Defined by the ER/PR/HER2 Subtypes and a Surrogate Classification according to Tumor Grade and Immunohistochemical Biomarkers.
Carol A Parise, Vincent Caggiano.
J Cancer Epidemiol, 2014 Jun 24; 2014. PMID: 24955090    Free PMC article.
Highly Cited.
How does genome sequencing impact surgery?
Marlies S Reimers, Charla C Engels, +2 authors, Gerrit J Liefers.
Nat Rev Clin Oncol, 2014 Jun 25; 11(10). PMID: 24958181
Chromosomal instability selects gene copy-number variants encoding core regulators of proliferation in ER+ breast cancer.
David Endesfelder, Rebecca Burrell, +6 authors, Maik Kschischo.
Cancer Res, 2014 Jun 28; 74(17). PMID: 24970479    Free PMC article.
Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemia.
Smita Dandekar, Eleny Romanos-Sirakis, +9 authors, William L Carroll.
Br J Haematol, 2014 Jul 06; 167(1). PMID: 24995804    Free PMC article.
Pathway-centric integrative analysis identifies RRM2 as a prognostic marker in breast cancer associated with poor survival and tamoxifen resistance.
Nagireddy Putluri, Suman Maity, +19 authors, Arun Sreekumar.
Neoplasia, 2014 Jul 14; 16(5). PMID: 25016594    Free PMC article.
Predictors of recurrence in breast cancer subtypes with negative lymph node in a Chinese population.
Xia Liu, Yong Guan, +4 authors, Yun Niu.
Int J Clin Exp Pathol, 2014 Jul 18; 7(6). PMID: 25031741    Free PMC article.
Diagnostic tests based on gene expression profile in breast cancer: from background to clinical use.
Laura Zanotti, Alberto Bottini, +2 authors, Maria Rosa Cappelletti.
Tumour Biol, 2014 Jul 23; 35(9). PMID: 25048969
A nineteen gene-based risk score classifier predicts prognosis of colorectal cancer patients.
Seon-Kyu Kim, Seon-Young Kim, +4 authors, Jin Cheon Kim.
Mol Oncol, 2014 Jul 23; 8(8). PMID: 25049118    Free PMC article.
Computational prognostic indicators for breast cancer.
Xinan Yang, Xindi Ai, John M Cunningham.
Cancer Manag Res, 2014 Jul 23; 6. PMID: 25050076    Free PMC article.
S6K1 promotes invasiveness of breast cancer cells in a model of metastasis of triple-negative breast cancer.
Yekaterina B Khotskaya, Aarthi Goverdhan, +7 authors, Mien-Chie Hung.
Am J Transl Res, 2014 Jul 31; 6(4). PMID: 25075253    Free PMC article.
How transferable are recommendations of the era of treating conventionally defined breast cancer for the era of molecularly characterised breast cancer?
Robert Königsberg, Christian Dittrich.
Gland Surg, 2012 Nov 01; 1(3). PMID: 25083440    Free PMC article.
A joint analysis of metabolomics and genetics of breast cancer.
Xiaohu Tang, Chao-Chieh Lin, +3 authors, Jeffrey R Marks.
Breast Cancer Res, 2014 Aug 06; 16(4). PMID: 25091696    Free PMC article.
Highly Cited.
Pathogenesis, prevention, diagnosis and treatment of breast cancer.
Rupen Shah, Kelly Rosso, S David Nathanson.
World J Clin Oncol, 2014 Aug 13; 5(3). PMID: 25114845    Free PMC article.
Biological subtypes of breast cancer: Prognostic and therapeutic implications.
Ozlem Yersal, Sabri Barutca.
World J Clin Oncol, 2014 Aug 13; 5(3). PMID: 25114856    Free PMC article.
Highly Cited. Review.
Adjuvant chemotherapy in breast cancer: To use or not to use, the anthracyclines.
Jennifer A Crozier, Abhisek Swaika, Alvaro Moreno-Aspitia.
World J Clin Oncol, 2014 Aug 13; 5(3). PMID: 25114866    Free PMC article.
Reverse-phase protein array for prediction of patients at low risk of developing bone metastasis from breast cancer.
Naoki Hayashi, Ganiraju C Manyam, +6 authors, Naoto T Ueno.
Oncologist, 2014 Aug 15; 19(9). PMID: 25117064    Free PMC article.
Current status of predictive biomarkers for neoadjuvant therapy in esophageal cancer.
Norihisa Uemura, Tadashi Kondo.
World J Gastrointest Pathophysiol, 2014 Aug 19; 5(3). PMID: 25133032    Free PMC article.
A program to identify prognostic and predictive gene signatures.
Sam D Chorlton, Robin M Hallett, John A Hassell.
BMC Res Notes, 2014 Aug 20; 7. PMID: 25135081    Free PMC article.
Serum metabolomic profiles evaluated after surgery may identify patients with oestrogen receptor negative early breast cancer at increased risk of disease recurrence. Results from a retrospective study.
Leonardo Tenori, Catherine Oakman, +8 authors, Angelo Di Leo.
Mol Oncol, 2014 Aug 26; 9(1). PMID: 25151299    Free PMC article.
A molecular prognostic model predicts esophageal squamous cell carcinoma prognosis.
Hui-Hui Cao, Chun-Peng Zheng, +7 authors, Li-Yan Xu.
PLoS One, 2014 Aug 26; 9(8). PMID: 25153136    Free PMC article.
Preliminary Development and Evaluation of an Algorithm to Identify Breast Cancer Chemotherapy Toxicities Using Electronic Medical Records and Administrative Data.
Jeanne S Mandelblatt, Karl Huang, +13 authors, Larry Kushi.
J Oncol Pract, 2014 Aug 28; 11(1). PMID: 25161127    Free PMC article.
Genome-driven integrated classification of breast cancer validated in over 7,500 samples.
H Raza Ali, Oscar M Rueda, +4 authors, Carlos Caldas.
Genome Biol, 2014 Aug 29; 15(8). PMID: 25164602    Free PMC article.
Highly Cited.
Differential subcellular and extracellular localisations of proteins required for insulin-like growth factor- and extracellular matrix-induced signalling events in breast cancer progression.
Helen C Plant, Abhishek S Kashyap, +7 authors, David I Leavesley.
BMC Cancer, 2014 Aug 30; 14. PMID: 25167778    Free PMC article.
A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.
Hans Kristian Moen Vollan, Oscar M Rueda, +22 authors, Carlos Caldas.
Mol Oncol, 2014 Aug 30; 9(1). PMID: 25169931    Free PMC article.
Chemotherapy in early breast cancer: when, how and which one?
Marcus Schmidt.
Breast Care (Basel), 2014 Sep 02; 9(3). PMID: 25177256    Free PMC article.
Gene signatures of drug resistance predict patient survival in colorectal cancer.
Y Zheng, J Zhou, Y Tong.
Pharmacogenomics J, 2014 Sep 03; 15(2). PMID: 25179828    Free PMC article.
Prognostic significance of Bcl-2 expression in non-basal triple-negative breast cancer patients treated with anthracycline-based chemotherapy.
Jung Eun Choi, Su Hwan Kang, Soo Jung Lee, Young Kyung Bae.
Tumour Biol, 2014 Sep 03; 35(12). PMID: 25179840
A thirteen-gene expression signature predicts survival of patients with pancreatic cancer and identifies new genes of interest.
Timothy E Newhook, Edik M Blais, +6 authors, Todd W Bauer.
PLoS One, 2014 Sep 03; 9(9). PMID: 25180633    Free PMC article.
Biomarkers in early-stage non-small-cell lung cancer: current concepts and future directions.
Mauricio Burotto, Anish Thomas, +2 authors, Arun Rajan.
J Thorac Oncol, 2014 Sep 05; 9(11). PMID: 25185530    Free PMC article.
Genome-based risk prediction for early stage breast cancer.
Christina Adaniel, Komal Jhaveri, Adriana Heguy, Francisco J Esteva.
Oncologist, 2014 Sep 05; 19(10). PMID: 25187476    Free PMC article.
High infiltration of tumor-associated macrophages in triple-negative breast cancer is associated with a higher risk of distant metastasis.
Zhong-Yu Yuan, Rong-Zhen Luo, +2 authors, Cong Xue.
Onco Targets Ther, 2014 Sep 05; 7. PMID: 25187727    Free PMC article.
Societal cost-effectiveness analysis of the 21-gene assay in estrogen-receptor-positive, lymph-node-negative early-stage breast cancer in Japan.
Hideko Yamauchi, Chizuko Nakagawa, +9 authors, Seigo Nakamura.
BMC Health Serv Res, 2014 Sep 06; 14. PMID: 25190451    Free PMC article.
Prognostic and therapeutic significance of ribonucleotide reductase small subunit M2 in estrogen-negative breast cancers.
Hang Zhang, Xiyong Liu, +7 authors, Yun Yen.
BMC Cancer, 2014 Sep 13; 14. PMID: 25213022    Free PMC article.
A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling.
Romain Boidot, Samuel Branders, +3 authors, Olivier Feron.
Oncotarget, 2014 Sep 13; 5(16). PMID: 25216520    Free PMC article.
Preanalytical variables and performance of diagnostic RNA-based gene expression analysis in breast cancer.
Christopher Poremba, Jennifer Uhlendorff, +10 authors, Carsten Denkert.
Virchows Arch, 2014 Sep 15; 465(4). PMID: 25218890    Free PMC article.
Retinoblastoma tumor suppressor pathway in breast cancer: prognosis, precision medicine, and therapeutic interventions.
Agnieszka K Witkiewicz, Erik S Knudsen.
Breast Cancer Res, 2014 Sep 17; 16(3). PMID: 25223380    Free PMC article.
Hurdles on the road to personalized medicine.
Thomas Tursz, Rene Bernards.
Mol Oncol, 2014 Sep 18; 9(5). PMID: 25226812    Free PMC article.
The impact of Oncotype DX testing on breast cancer management and chemotherapy prescribing patterns in a tertiary referral centre.
Terri Patricia McVeigh, Lauren M Hughes, +4 authors, Michael J Kerin.
Eur J Cancer, 2014 Sep 23; 50(16). PMID: 25240289    Free PMC article.
Increased expression of tumor proliferation genes in Hispanic women with early-stage breast cancer.
Kevin Kalinsky, Emerson A Lim, +10 authors, Dawn L Hershman.
Cancer Invest, 2014 Sep 26; 32(9). PMID: 25254601    Free PMC article.
Dynamic classification using case-specific training cohorts outperforms static gene expression signatures in breast cancer.
Balázs Győrffy, Thomas Karn, +3 authors, Lajos Pusztai.
Int J Cancer, 2014 Oct 03; 136(9). PMID: 25274406    Free PMC article.
Claudin-low breast cancers: clinical, pathological, molecular and prognostic characterization.
Renaud Sabatier, Pascal Finetti, +5 authors, François Bertucci.
Mol Cancer, 2014 Oct 04; 13. PMID: 25277734    Free PMC article.
Translational research in oncology--10 years of progress and future prospects.
James H Doroshow, Shivaani Kummar.
Nat Rev Clin Oncol, 2014 Oct 08; 11(11). PMID: 25286976
A four-long non-coding RNA signature in predicting breast cancer survival.
Jin Meng, Ping Li, +2 authors, Shen Fu.
J Exp Clin Cancer Res, 2014 Oct 08; 33. PMID: 25288503    Free PMC article.
Highly Cited.
Prognostic relevance of biological subtype overrides that of TNM staging in breast cancer: discordance between stage and biology.
Hyun Ae Jung, Yeon Hee Park, +10 authors, Young-Hyuck Im.
Tumour Biol, 2014 Oct 20; 36(2). PMID: 25326808
Update on adjuvant chemotherapy for early breast cancer.
Murtuza M Rampurwala, Gabrielle B Rocque, Mark E Burkard.
Breast Cancer (Auckl), 2014 Oct 23; 8. PMID: 25336961    Free PMC article.
Prognostic influence of pre-operative C-reactive protein in node-negative breast cancer patients.
Isabel Sicking, Karolina Edlund, +10 authors, Marcus Schmidt.
PLoS One, 2014 Oct 24; 9(10). PMID: 25340395    Free PMC article.
Estrogen receptor expression is high but is of lower intensity in tubular carcinoma than in well-differentiated invasive ductal carcinoma.
Julie M Jorns, Dafydd G Thomas, +7 authors, Daniel W Visscher.
Arch Pathol Lab Med, 2014 Oct 31; 138(11). PMID: 25357113    Free PMC article.
NCCN Working Group report: designing clinical trials in the era of multiple biomarkers and targeted therapies.
Alan P Venook, Maria E Arcila, +15 authors, Marian L Birkeland.
J Natl Compr Canc Netw, 2014 Nov 02; 12(11). PMID: 25361808    Free PMC article.
Development of circulating tumor cell-endocrine therapy index in patients with hormone receptor-positive breast cancer.
Costanza Paoletti, Maria C Muñiz, +13 authors, Daniel F Hayes.
Clin Cancer Res, 2014 Nov 09; 21(11). PMID: 25381338    Free PMC article.
The clinical impact of 21-gene recurrence score on treatment decisions for patients with hormone receptor-positive early breast cancer in Korea.
Moo Hyun Lee, Wonshik Han, +7 authors, Eun Sook Lee.
Cancer Res Treat, 2014 Nov 11; 47(2). PMID: 25381828    Free PMC article.
Integrated DNA Copy Number and Gene Expression Regulatory Network Analysis of Non-small Cell Lung Cancer Metastasis.
Seyed M Iranmanesh, Nancy L Guo.
Cancer Inform, 2014 Nov 14; 13(Suppl 5). PMID: 25392690    Free PMC article.
Imaging tumour heterogeneity of the consequences of a PKCα-substrate interaction in breast cancer patients.
Gregory Weitsman, Katherine Lawler, +18 authors, Tony Ng.
Biochem Soc Trans, 2014 Nov 18; 42(6). PMID: 25399560    Free PMC article.
Transfer of clinically relevant gene expression signatures in breast cancer: from Affymetrix microarray to Illumina RNA-Sequencing technology.
Debora Fumagalli, Alexis Blanchet-Cohen, +13 authors, Benjamin Haibe-Kains.
BMC Genomics, 2014 Nov 22; 15. PMID: 25412710    Free PMC article.
Estrogen independent gene expression defines clinically relevant subgroups of estrogen receptor positive breast cancer.
Robin M Hallett, John A Hassell.
BMC Cancer, 2014 Nov 26; 14. PMID: 25420785    Free PMC article.
SWOG S0221: a phase III trial comparing chemotherapy schedules in high-risk early-stage breast cancer.
George T Budd, William E Barlow, +17 authors, Gabriel N Hortobagyi.
J Clin Oncol, 2014 Nov 26; 33(1). PMID: 25422488    Free PMC article.
Expression levels of SF3B3 correlate with prognosis and endocrine resistance in estrogen receptor-positive breast cancer.
Yesim Gökmen-Polar, Yaseswini Neelamraju, +4 authors, Sunil Badve.
Mod Pathol, 2014 Nov 29; 28(5). PMID: 25431237
Post-operative nomogram for predicting freedom from recurrence after surgery in localised breast cancer receiving adjuvant hormone therapy.
Chafika Mazouni, Frédéric Fina, +3 authors, Pierre-Marie Martin.
J Cancer Res Clin Oncol, 2014 Dec 01; 141(6). PMID: 25433507
Biology of breast cancer in young women.
Hatem A Azim, Ann H Partridge.
Breast Cancer Res, 2014 Dec 02; 16(4). PMID: 25436920    Free PMC article.
Highly Cited. Review.
E2F4 regulatory program predicts patient survival prognosis in breast cancer.
Sari S Khaleel, Erik H Andrews, +2 authors, Chao Cheng.
Breast Cancer Res, 2014 Dec 03; 16(6). PMID: 25440089    Free PMC article.
Unbiased approaches to biomarker discovery in neurodegenerative diseases.
Alice S Chen-Plotkin.
Neuron, 2014 Dec 03; 84(3). PMID: 25442938    Free PMC article.
Inclusion of KI67 significantly improves performance of the PREDICT prognostication and prediction model for early breast cancer.
Gordon C Wishart, Emad Rakha, +6 authors, Paul D P Pharoah.
BMC Cancer, 2014 Dec 05; 14. PMID: 25472026    Free PMC article.
The 21-gene recurrence score and locoregional recurrence in breast cancer patients.
Naresh K Jegadeesh, Sunjin Kim, +7 authors, Mylin A Torres.
Ann Surg Oncol, 2014 Dec 05; 22(4). PMID: 25472643    Free PMC article.
Clinical utility of gene-expression profiling in women with early breast cancer: an overview of systematic reviews.
Michael Marrone, Alison Stewart, W David Dotson.
Genet Med, 2014 Dec 05; 17(7). PMID: 25474343    Free PMC article.
The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis.
Siwanon Jirawatnotai, Samanta Sharma, +7 authors, Piotr Sicinski.
Cell cycle (Georgetown, Tex.), 2014 Dec 09; 13(18). PMID: 25486477    Free PMC article.
Emerging gene-based prognostic tools in early breast cancer: First steps to personalised medicine.
Umar Wazir, Kefah Mokbel.
World J Clin Oncol, 2014 Dec 11; 5(5). PMID: 25493218    Free PMC article.
Association of survivin splice variants with prognosis and treatment of breast cancer.
Anastasia Pavlidou, Christos Kroupis, Kleanthi Dimas.
World J Clin Oncol, 2014 Dec 11; 5(5). PMID: 25493226    Free PMC article.
The histone chaperone HJURP is a new independent prognostic marker for luminal A breast carcinoma.
Rocío Montes de Oca, Zachary A Gurard-Levin, +12 authors, Geneviève Almouzni.
Mol Oncol, 2014 Dec 17; 9(3). PMID: 25497280    Free PMC article.
Role of urokinase plasminogen activator and plasminogen activator inhibitor mRNA expression as prognostic factors in molecular subtypes of breast cancer.
Isabell Witzel, Karin Milde-Langosch, +8 authors, Volkmar Müller.
Onco Targets Ther, 2014 Dec 17; 7. PMID: 25506225    Free PMC article.
A genome wide meta-analysis study for identification of common variation associated with breast cancer prognosis.
Sajjad Rafiq, Sofia Khan, +9 authors, Diana Eccles.
PLoS One, 2014 Dec 20; 9(12). PMID: 25526632    Free PMC article.
A guide for clinicians in the evaluation of emerging molecular diagnostics for newly diagnosed prostate cancer.
Steven E Canfield, Adam S Kibel, +3 authors, Judd W Moul.
Rev Urol, 2014 Dec 31; 16(4). PMID: 25548544    Free PMC article.
Patterns of 21-gene assay testing and chemotherapy use in black and white breast cancer patients.
Vanessa B Sheppard, Suzanne C O'Neill, +3 authors, Claudine Isaacs.
Clin Breast Cancer, 2015 Jan 04; 15(2). PMID: 25555816    Free PMC article.
Individualized Survival and Treatment Response Predictions in Breast Cancer Patients: Involvements of Phospho-EGFR and Phospho-Her2/neu Proteins.
Lan Guo, Jame Abraham, +3 authors, Yong Qian.
Open Clin Cancer J, 2008 May 27; 2. PMID: 25558292    Free PMC article.
Clinical utility of gene expression profiling data for clinical decision-making regarding adjuvant therapy in early stage, node-negative breast cancer: a case report.
Steven R Schuster, Barbara A Pockaj, +2 authors, Donald W Northfelt.
J Pers Med, 2012 Jan 01; 2(3). PMID: 25562201    Free PMC article.
Understanding the economic value of molecular diagnostic tests: case studies and lessons learned.
Adrian Towse, Diego Ossa, +2 authors, Louis Garrison.
J Pers Med, 2013 Jan 01; 3(4). PMID: 25562729    Free PMC article.
Emerging understanding of multiscale tumor heterogeneity.
Michael J Gerdes, Anup Sood, +3 authors, Fiona Ginty.
Front Oncol, 2015 Jan 08; 4. PMID: 25566504    Free PMC article.
The future of breast cancer systemic therapy: the next 10 years.
Melinda L Telli, George W Sledge.
J Mol Med (Berl), 2015 Jan 09; 93(2). PMID: 25566982
Open pipelines for integrated tumor genome profiles reveal differences between pancreatic cancer tumors and cell lines.
Jeremy Goecks, Bassel F El-Rayes, +3 authors, Michael R Rossi.
Cancer Med, 2015 Jan 17; 4(3). PMID: 25594743    Free PMC article.
Raf kinase inhibitory protein (RKIP) as a metastasis suppressor: regulation of signaling networks in cancer.
Ali E Yesilkanal, Marsha Rich Rosner.
Crit Rev Oncog, 2015 Jan 20; 19(6). PMID: 25597354    Free PMC article.
A three-protein signature and clinical outcome in esophageal squamous cell carcinoma.
Hui-Hui Cao, Shi-Yi Zhang, +5 authors, Li-Yan Xu.
Oncotarget, 2015 Jan 22; 6(7). PMID: 25605255    Free PMC article.
Multifunctional Polymeric Micelles Co-loaded with Anti-Survivin siRNA and Paclitaxel Overcome Drug Resistance in an Animal Model of Ovarian Cancer.
Giuseppina Salzano, Gemma Navarro, +2 authors, Vladimir P Torchilin.
Molecular cancer therapeutics, 2015 Feb 07; 14(4). PMID: 25657335    Free PMC article.
Tailoring cancer radiotherapy through genotyping, how close are we?
O Mahmoud, B G Haffty.
Br J Radiol, 2015 Feb 11; 88(1051). PMID: 25668486    Free PMC article.
The 21-gene recurrence score complements IBTR! Estimates in early-stage, hormone receptor-positive, HER2-normal, lymph node-negative breast cancer.
Nikhil G Thaker, Karen E Hoffman, +10 authors, Wendy A Woodward.
Springerplus, 2015 Feb 13; 4. PMID: 25674496    Free PMC article.
Identification of metastasis-suppressive microRNAs in primary melanoma.
Doug Hanniford, Miguel F Segura, +9 authors, Eva Hernando.
J Natl Cancer Inst, 2015 Feb 14; 107(3). PMID: 25677173    Free PMC article.
Lack of effect of metformin on mammary carcinogenesis in nondiabetic rat and mouse models.
Matthew D Thompson, Clinton J Grubbs, +10 authors, Ronald A Lubet.
Cancer Prev Res (Phila), 2015 Feb 15; 8(3). PMID: 25681088    Free PMC article.
CCR 20th Anniversary commentary: stayin' alive-antiapoptotic proteins and breast cancer.
Douglas Yee.
Clin Cancer Res, 2015 Feb 19; 21(4). PMID: 25691771    Free PMC article.
Application of metabolomics in drug resistant breast cancer research.
Ayesha N Shajahan-Haq, Mehar S Cheema, Robert Clarke.
Metabolites, 2015 Feb 19; 5(1). PMID: 25693144    Free PMC article.
Precision medicine in breast cancer: genes, genomes, and the future of genomically driven treatments.
Daniel G Stover, Nikhil Wagle.
Curr Oncol Rep, 2015 Feb 25; 17(4). PMID: 25708799    Free PMC article.
The predictive accuracy of PREDICT: a personalized decision-making tool for Southeast Asian women with breast cancer.
Hoong-Seam Wong, Shridevi Subramaniam, +7 authors, Nirmala Bhoo-Pathy.
Medicine (Baltimore), 2015 Feb 26; 94(8). PMID: 25715267    Free PMC article.
The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine.
Lao H Saal, Johan Vallon-Christersson, +16 authors, Åke Borg.
Genome Med, 2015 Feb 28; 7(1). PMID: 25722745    Free PMC article.
Study of integrated heterogeneous data reveals prognostic power of gene expression for breast cancer survival.
Richard E Neapolitan, Xia Jiang.
PLoS One, 2015 Feb 28; 10(2). PMID: 25723490    Free PMC article.
APOBEC3B expression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation.
David W Cescon, Benjamin Haibe-Kains, Tak W Mak.
Proc Natl Acad Sci U S A, 2015 Mar 03; 112(9). PMID: 25730878    Free PMC article.
Highly Cited.
Gene expression profile predictive of response to chemotherapy in metastatic colorectal cancer.
Purificacion Estevez-Garcia, Fernando Rivera, +8 authors, Rocio Garcia-Carbonero.
Oncotarget, 2015 Mar 03; 6(8). PMID: 25730906    Free PMC article.
How can we best respect patient autonomy in breast cancer treatment decisions?
Kathryn A Martinez, Allison W Kurian, Sarah T Hawley, Reshma Jagsi.
Breast Cancer Manag, 2015 Mar 04; 4(1). PMID: 25733982    Free PMC article.
Inhibition of cancer cell proliferation and breast tumor targeting of pHLIP-monomethyl auristatin E conjugates.
Kelly E Burns, Matthew K Robinson, Damien Thévenin.
Mol Pharm, 2015 Mar 06; 12(4). PMID: 25741818    Free PMC article.
The value of personalizing medicine: medical oncologists' views on gene expression profiling in breast cancer treatment.
Yvonne Bombard, Linda Rozmovits, +3 authors, Deborah A Marshall.
Oncologist, 2015 Mar 10; 20(4). PMID: 25746345    Free PMC article.
Machine learning applications in cancer prognosis and prediction.
Konstantina Kourou, Themis P Exarchos, +2 authors, Dimitrios I Fotiadis.
Comput Struct Biotechnol J, 2015 Mar 10; 13. PMID: 25750696    Free PMC article.
Highly Cited. Review.
Network-based approach to identify prognostic biomarkers for estrogen receptor-positive breast cancer treatment with tamoxifen.
Rong Liu, Cheng-Xian Guo, Hong-Hao Zhou.
Cancer biology & therapy, 2015 Mar 11; 16(2). PMID: 25756514    Free PMC article.
Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease.
Maurice P H M Jansen, Leen Sas, +20 authors, Steven Van Laere.
Mol Oncol, 2015 Mar 17; 9(6). PMID: 25771305    Free PMC article.
Integrated analysis of DNA methylation, immunohistochemistry and mRNA expression, data identifies a methylation expression index (MEI) robustly associated with survival of ER-positive breast cancer patients.
Jonine D Figueroa, Howard Yang, +6 authors, Maxwell Lee.
Breast Cancer Res Treat, 2015 Mar 17; 150(2). PMID: 25773928    Free PMC article.
A retrospective study of the impact of 21-gene recurrence score assay on treatment choice in node positive micrometastatic breast cancer.
Thomas G Frazier, Kevin R Fox, +13 authors, Michael S Broder.
Pharmaceuticals (Basel), 2015 Mar 20; 8(1). PMID: 25789420    Free PMC article.
In the era of genomics, should tumor size be reconsidered as a criterion for neoadjuvant chemotherapy?
Xavier Pivot, Laura Mansi, +14 authors, Christian Villanueva.
Oncologist, 2015 Mar 22; 20(4). PMID: 25795632    Free PMC article.
Breast cancer under age 40: a different approach.
D Ribnikar, J M Ribeiro, +6 authors, F Cardoso.
Curr Treat Options Oncol, 2015 Mar 23; 16(4). PMID: 25796377
Comprehensive molecular screening: from the RT-PCR to the RNA-seq.
Carlota Costa, Ana Giménez-Capitán, Niki Karachaliou, Rafael Rosell.
Transl Lung Cancer Res, 2013 Apr 01; 2(2). PMID: 25806219    Free PMC article.
Retrospective analysis of metastatic behaviour of breast cancer subtypes.
C Dilara Savci-Heijink, Hans Halfwerk, +3 authors, Marc J van de Vijver.
Breast Cancer Res Treat, 2015 Mar 31; 150(3). PMID: 25820592    Free PMC article.
Molecular portraits: the evolution of the concept of transcriptome-based cancer signatures.
Angelika Modelska, Alessandro Quattrone, Angela Re.
Brief Bioinform, 2015 Apr 03; 16(6). PMID: 25832647    Free PMC article.
A phase 1 trial of preoperative partial breast radiation therapy: Patient selection, target delineation, and dose delivery.
Rachel C Blitzblau, Ritu Arya, +5 authors, Janet K Horton.
Pract Radiat Oncol, 2015 Apr 04; 5(5). PMID: 25834942    Free PMC article.
[Molecular pathology for breast cancer: Importance of the gene expression profile].
C Denkert, B M Pfitzner, B I Heppner, M Dietel.
Pathologe, 2015 Apr 04; 36(2). PMID: 25836324
An integrated quantification method to increase the precision, robustness, and resolution of protein measurement in human plasma samples.
Xiao-Jun Li, Lik Wee Lee, +8 authors, Paul Kearney.
Clin Proteomics, 2015 Apr 04; 12(1). PMID: 25838814    Free PMC article.
Multigene prognostic tests in breast cancer: past, present, future.
Balázs Győrffy, Christos Hatzis, +3 authors, Lajos Pusztai.
Breast Cancer Res, 2015 Apr 08; 17. PMID: 25848861    Free PMC article.
Highly Cited. Review.
Markers for the identification of late breast cancer recurrence.
Ivana Sestak, Jack Cuzick.
Breast Cancer Res, 2015 Apr 08; 17. PMID: 25848913    Free PMC article.
Molecular subtyping for clinically defined breast cancer subgroups.
Xi Zhao, Einar Andreas Rødland, Robert Tibshirani, Sylvia Plevritis.
Breast Cancer Res, 2015 Apr 08; 17. PMID: 25849221    Free PMC article.
Patient-derived xenograft models of breast cancer and their predictive power.
James R Whittle, Michael T Lewis, Geoffrey J Lindeman, Jane E Visvader.
Breast Cancer Res, 2015 Apr 08; 17. PMID: 25849559    Free PMC article.
Highly Cited. Review.
Breast cancer subtype intertumor heterogeneity: MRI-based features predict results of a genomic assay.
Elizabeth J Sutton, Jung Hun Oh, +5 authors, Elizabeth A Morris.
J Magn Reson Imaging, 2015 Apr 09; 42(5). PMID: 25850931    Free PMC article.
Highly Cited.
Integrative analysis of survival-associated gene sets in breast cancer.
Frederick S Varn, Matthew H Ung, Shao Ke Lou, Chao Cheng.
BMC Med Genomics, 2015 Apr 17; 8. PMID: 25881247    Free PMC article.
Prognostic value of a 92-probe signature in breast cancer.
Salima Akter, Tae Gyu Choi, +17 authors, Sung Soo Kim.
Oncotarget, 2015 Apr 18; 6(17). PMID: 25883221    Free PMC article.
Evaluation of public cancer datasets and signatures identifies TP53 mutant signatures with robust prognostic and predictive value.
Brian David Lehmann, Yan Ding, +6 authors, Yajun Yi.
BMC Cancer, 2015 Apr 18; 15. PMID: 25886164    Free PMC article.
Fuzzy logic selection as a new reliable tool to identify molecular grade signatures in breast cancer--the INNODIAG study.
Tatiana Kempowsky-Hamon, Carine Valle, +12 authors, Véronique Anton-Leberre.
BMC Med Genomics, 2015 Apr 19; 8. PMID: 25888889    Free PMC article.
FKBPL: a marker of good prognosis in breast cancer.
Laura Nelson, Hayley D McKeen, +27 authors, Tracy Robson.
Oncotarget, 2015 Apr 25; 6(14). PMID: 25906750    Free PMC article.
Defining breast cancer intrinsic subtypes by quantitative receptor expression.
Maggie C U Cheang, Miguel Martin, +21 authors, Lisa A Carey.
Oncologist, 2015 Apr 25; 20(5). PMID: 25908555    Free PMC article.
OGFOD1 is required for breast cancer cell proliferation and is associated with poor prognosis in breast cancer.
Jae-Hwan Kim, Soon-Min Lee, +9 authors, Hong-Duk Youn.
Oncotarget, 2015 Apr 25; 6(23). PMID: 25909288    Free PMC article.
Insulin-like growth factor-1 receptor is associated with better prognosis in classical Hodgkin's lymphoma: Correlation with MET expression.
Young Wha Koh, Dok Hyun Yoon, +2 authors, Jooryung Huh.
Int J Exp Pathol, 2015 Apr 29; 96(4). PMID: 25916750    Free PMC article.
Developing a new generation of breast cancer clinical gene expression tests.
Zuzana Kos, Torsten O Nielsen.
Breast Cancer Res, 2014 Jan 01; 16(4). PMID: 25928431    Free PMC article.
Use of modified Magee equations and histologic criteria to predict the Oncotype DX recurrence score.
Bradley M Turner, Kristin A Skinner, +6 authors, David G Hicks.
Mod Pathol, 2015 May 02; 28(7). PMID: 25932962
Low ATM protein expression in malignant tumor as well as cancer-associated stroma are independent prognostic factors in a retrospective study of early-stage hormone-negative breast cancer.
Xiaolan Feng, Haocheng Li, +8 authors, Gwyn Bebb.
Breast Cancer Res, 2015 May 04; 17. PMID: 25935535    Free PMC article.
Comparing Platforms for Messenger RNA Expression Profiling of Archival Formalin-Fixed, Paraffin-Embedded Tissues.
Svitlana Tyekucheva, Neil E Martin, +10 authors, Michael Birrer.
J Mol Diagn, 2015 May 06; 17(4). PMID: 25937617    Free PMC article.
Role of genetic and molecular profiling in sarcomas.
Scott M Norberg, Sujana Movva.
Curr Treat Options Oncol, 2015 May 06; 16(5). PMID: 25939540
Association between ¹⁸F-FDG uptake and molecular subtype of breast cancer.
Kazuhiro Kitajima, Kazuhito Fukushima, +6 authors, Shozo Hirota.
Eur J Nucl Med Mol Imaging,