Journal Article
. 2005 Feb;365(9460).
doi: 10.1016/S0140-6736(05)17947-1.

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

Yixin Wang 1 Jan G M Klijn  Yi Zhang  Anieta M Sieuwerts  Maxime P Look  Fei Yang  Dmitri Talantov  Mieke Timmermans  Marion E Meijer-van Gelder  Jack Yu  Tim Jatkoe  Els M J J Berns  David Atkins  John A Foekens  
Affiliations
  • PMID: 15721472
  •     1156 citations

Abstract

Background: Genome-wide measures of gene expression can identify patterns of gene activity that subclassify tumours and might provide a better means than is currently available for individual risk assessment in patients with lymph-node-negative breast cancer.

Methods: We analysed, with Affymetrix Human U133a GeneChips, the expression of 22000 transcripts from total RNA of frozen tumour samples from 286 lymph-node-negative patients who had not received adjuvant systemic treatment.

Findings: In a training set of 115 tumours, we identified a 76-gene signature consisting of 60 genes for patients positive for oestrogen receptors (ER) and 16 genes for ER-negative patients. This signature showed 93% sensitivity and 48% specificity in a subsequent independent testing set of 171 lymph-node-negative patients. The gene profile was highly informative in identifying patients who developed distant metastases within 5 years (hazard ratio 5.67 [95% CI 2.59-12.4]), even when corrected for traditional prognostic factors in multivariate analysis (5.55 [2.46-12.5]). The 76-gene profile also represented a strong prognostic factor for the development of metastasis in the subgroups of 84 premenopausal patients (9.60 [2.28-40.5]), 87 postmenopausal patients (4.04 [1.57-10.4]), and 79 patients with tumours of 10-20 mm (14.1 [3.34-59.2]), a group of patients for whom prediction of prognosis is especially difficult.

Interpretation: The identified signature provides a powerful tool for identification of patients at high risk of distant recurrence. The ability to identify patients who have a favourable prognosis could, after independent confirmation, allow clinicians to avoid adjuvant systemic therapy or to choose less aggressive therapeutic options.

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Review.
Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells.
Pravin J Mishra, Prasun J Mishra, +6 authors, Debabrata Banerjee.
Cancer Res, 2008 Jun 04; 68(11). PMID: 18519693    Free PMC article.
Highly Cited.
Molecular imaging of metastatic potential.
Paul T Winnard, Arvind P Pathak, +3 authors, Martin G Pomper.
J Nucl Med, 2008 Jul 01; 49 Suppl 2. PMID: 18523068    Free PMC article.
Review.
Development of a clinically feasible molecular assay to predict recurrence of stage II colon cancer.
Yuqiu Jiang, Graham Casey, +9 authors, Yixin Wang.
J Mol Diagn, 2008 Jun 17; 10(4). PMID: 18556775    Free PMC article.
Prognostic relevance of glucosylceramide synthase (GCS) expression in breast cancer.
Eugen Ruckhäberle, Thomas Karn, +5 authors, Achim Rody.
J Cancer Res Clin Oncol, 2008 Jun 19; 135(1). PMID: 18560890
An expression signature of estrogen-regulated genes predicts disease-free survival in tamoxifen-treated patients better than progesterone receptor status.
Marc E Lippman, James M Rae, Arul M Chinnaiyan.
Trans Am Clin Climatol Assoc, 2008 Jul 04; 119. PMID: 18596862    Free PMC article.
A comparative study of survival models for breast cancer prognostication based on microarray data: does a single gene beat them all?
B Haibe-Kains, C Desmedt, C Sotiriou, G Bontempi.
Bioinformatics, 2008 Jul 19; 24(19). PMID: 18635567    Free PMC article.
A precisely regulated gene expression cassette potently modulates metastasis and survival in multiple solid cancers.
Kun Yu, Kumaresan Ganesan, +10 authors, Patrick Tan.
PLoS Genet, 2008 Jul 19; 4(7). PMID: 18636107    Free PMC article.
Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays.
David I Rodenhiser, Joseph Andrews, +4 authors, Ann F Chambers.
Breast Cancer Res, 2008 Jul 22; 10(4). PMID: 18638373    Free PMC article.
Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures.
Pratyaksha Wirapati, Christos Sotiriou, +10 authors, Mauro Delorenzi.
Breast Cancer Res, 2008 Jul 30; 10(4). PMID: 18662380    Free PMC article.
Highly Cited.
Pooling breast cancer datasets has a synergetic effect on classification performance and improves signature stability.
Martin H van Vliet, Fabien Reyal, +3 authors, Lodewyk F A Wessels.
BMC Genomics, 2008 Aug 08; 9. PMID: 18684329    Free PMC article.
A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospects.
Bas J Wouters, Bob Löwenberg, Ruud Delwel.
Blood, 2008 Aug 16; 113(2). PMID: 18703705    Free PMC article.
Review.
Prognostic breast cancer signature identified from 3D culture model accurately predicts clinical outcome across independent datasets.
Katherine J Martin, Denis R Patrick, Mina J Bissell, Marcia V Fournier.
PLoS One, 2008 Aug 21; 3(8). PMID: 18714348    Free PMC article.
Highly Cited.
Combining biological gene expression signatures in predicting outcome in breast cancer: An alternative to supervised classification.
Dimitry S A Nuyten, Trevor Hastie, +2 authors, Marc J van de Vijver.
Eur J Cancer, 2008 Aug 22; 44(15). PMID: 18715778    Free PMC article.
Comparison of prognostic gene expression signatures for breast cancer.
Benjamin Haibe-Kains, Christine Desmedt, +6 authors, Christos Sotiriou.
BMC Genomics, 2008 Aug 23; 9. PMID: 18717985    Free PMC article.
Supervised principal component analysis for gene set enrichment of microarray data with continuous or survival outcomes.
Xi Chen, Lily Wang, Jonathan D Smith, Bing Zhang.
Bioinformatics, 2008 Aug 30; 24(21). PMID: 18753155    Free PMC article.
A robust classifier of high predictive value to identify good prognosis patients in ER-negative breast cancer.
Andrew E Teschendorff, Carlos Caldas.
Breast Cancer Res, 2008 Aug 30; 10(4). PMID: 18755024    Free PMC article.
Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer.
Omar Khalid, Sanjeev K Baniwal, +5 authors, Baruch Frenkel.
Endocrinology, 2008 Aug 30; 149(12). PMID: 18755791    Free PMC article.
Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer.
John A Foekens, Anieta M Sieuwerts, +6 authors, John W M Martens.
Proc Natl Acad Sci U S A, 2008 Aug 30; 105(35). PMID: 18755890    Free PMC article.
Highly Cited.
Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis.
Chad J Creighton, Angelo Casa, +5 authors, Adrian V Lee.
J Clin Oncol, 2008 Sep 02; 26(25). PMID: 18757322    Free PMC article.
Highly Cited.
Gene expression variation to predict 10-year survival in lymph-node-negative breast cancer.
Elin Karlsson, Ulla Delle, +4 authors, Khalil Helou.
BMC Cancer, 2008 Sep 10; 8. PMID: 18778486    Free PMC article.
Identification of a gene signature in cell cycle pathway for breast cancer prognosis using gene expression profiling data.
Jiangang Liu, Andrew Campen, +6 authors, Shuyu Li.
BMC Med Genomics, 2008 Sep 13; 1. PMID: 18786252    Free PMC article.
Cytochrome P450 2D6 and homeobox 13/interleukin-17B receptor: combining inherited and tumor gene markers for prediction of tamoxifen resistance.
Matthew P Goetz, Vera J Suman, +12 authors, James N Ingle.
Clin Cancer Res, 2008 Sep 17; 14(18). PMID: 18794098    Free PMC article.
Development of resistance to targeted therapies transforms the clinically associated molecular profile subtype of breast tumor xenografts.
Chad J Creighton, Suleiman Massarweh, +6 authors, Rachel Schiff.
Cancer Res, 2008 Sep 17; 68(18). PMID: 18794137    Free PMC article.
The removal of multiplicative, systematic bias allows integration of breast cancer gene expression datasets - improving meta-analysis and prediction of prognosis.
Andrew H Sims, Graeme J Smethurst, +5 authors, Robert B Clarke.
BMC Med Genomics, 2008 Sep 23; 1. PMID: 18803878    Free PMC article.
Integrative bioinformatics analysis of transcriptional regulatory programs in breast cancer cells.
Atsushi Niida, Andrew D Smith, +4 authors, Tetsu Akiyama.
BMC Bioinformatics, 2008 Oct 01; 9. PMID: 18823535    Free PMC article.
Transforming growth factor-beta signaling: emerging stem cell target in metastatic breast cancer?
Antoinette R Tan, Gabriela Alexe, Michael Reiss.
Breast Cancer Res Treat, 2008 Oct 09; 115(3). PMID: 18841463    Free PMC article.
Review.
Gene expression profiling of breast cancer.
Ting Bao, Nancy E Davidson.
Adv Surg, 2008 Oct 29; 42. PMID: 18953822    Free PMC article.
Review.
Robust prognostic value of a knowledge-based proliferation signature across large patient microarray studies spanning different cancer types.
M H W Starmans, B Krishnapuram, +8 authors, P Lambin.
Br J Cancer, 2008 Nov 06; 99(11). PMID: 18985037    Free PMC article.
Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer.
Charles Swanton, Zoltan Szallasi, James D Brenton, Julian Downward.
Breast Cancer Res, 2008 Nov 07; 10(5). PMID: 18986507    Free PMC article.
Review.
Inferring pathway activity toward precise disease classification.
Eunjung Lee, Han-Yu Chuang, +2 authors, Doheon Lee.
PLoS Comput Biol, 2008 Nov 08; 4(11). PMID: 18989396    Free PMC article.
Highly Cited.
A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer.
Fabien Reyal, Martin H van Vliet, +10 authors, Lodewyk F A Wessels.
Breast Cancer Res, 2008 Nov 19; 10(6). PMID: 19014521    Free PMC article.
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classification.
Michael Gormley, Aydin Tozeren.
BMC Bioinformatics, 2008 Nov 19; 9. PMID: 19014681    Free PMC article.
Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature.
Andrew Tutt, Alice Wang, +21 authors, Fred Waldman.
BMC Cancer, 2008 Nov 26; 8. PMID: 19025599    Free PMC article.
A functional Notch-survivin gene signature in basal breast cancer.
Connie W Lee, Karl Simin, +5 authors, Dario C Altieri.
Breast Cancer Res, 2008 Nov 26; 10(6). PMID: 19025652    Free PMC article.
Molecular characterisation of the tumour microenvironment in breast cancer.
Min Hu, Kornelia Polyak.
Eur J Cancer, 2008 Nov 26; 44(18). PMID: 19026532    Free PMC article.
Review.
In vitro and in vivo analysis of B-Myb in basal-like breast cancer.
A R Thorner, K A Hoadley, +3 authors, C M Perou.
Oncogene, 2008 Dec 02; 28(5). PMID: 19043454    Free PMC article.
Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells.
Bérengère Marty, Virginie Maire, +15 authors, Thierry Dubois.
Breast Cancer Res, 2008 Dec 06; 10(6). PMID: 19055754    Free PMC article.
Mechanisms of metastasis.
Kent W Hunter, Nigel P S Crawford, Jude Alsarraj.
Breast Cancer Res, 2009 Jan 06; 10 Suppl 1. PMID: 19091006    Free PMC article.
Review.
Haptoglobin phenotype is not a predictor of recurrence free survival in high-risk primary breast cancer patients.
Marie-Christine W Gast, Harm van Tinteren, +10 authors, Jos H Beijnen.
BMC Cancer, 2008 Dec 26; 8. PMID: 19108738    Free PMC article.
MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer.
Guohong Hu, Robert A Chong, +7 authors, Yibin Kang.
Cancer Cell, 2008 Dec 30; 15(1). PMID: 19111877    Free PMC article.
Highly Cited.
Gene expression meta-analysis identifies metastatic pathways and transcription factors in breast cancer.
Mads Thomassen, Qihua Tan, Torben A Kruse.
BMC Cancer, 2009 Jan 01; 8. PMID: 19116006    Free PMC article.
The origins of breast cancer prognostic gene expression profiles.
Luanne Lukes, Nigel P S Crawford, Renard Walker, Kent W Hunter.
Cancer Res, 2009 Jan 02; 69(1). PMID: 19118016    Free PMC article.
Gene expression of ceramide kinase, galactosyl ceramide synthase and ganglioside GD3 synthase is associated with prognosis in breast cancer.
Eugen Ruckhäberle, Thomas Karn, +5 authors, Manfred Kaufmann.
J Cancer Res Clin Oncol, 2009 Jan 07; 135(8). PMID: 19125296
Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers.
Jérôme Eeckhoute, Mathieu Lupien, +4 authors, Myles Brown.
Genome Res, 2009 Jan 09; 19(3). PMID: 19129543    Free PMC article.
On reliable discovery of molecular signatures.
Roland Nilsson, Johan Björkegren, Jesper Tegnér.
BMC Bioinformatics, 2009 Jan 31; 10. PMID: 19178740    Free PMC article.
Selecting control genes for RT-QPCR using public microarray data.
Vlad Popovici, Darlene R Goldstein, +3 authors, Pratyaksha Wirapati.
BMC Bioinformatics, 2009 Feb 04; 10. PMID: 19187545    Free PMC article.
Supervised risk predictor of breast cancer based on intrinsic subtypes.
Joel S Parker, Michael Mullins, +17 authors, Philip S Bernard.
J Clin Oncol, 2009 Feb 11; 27(8). PMID: 19204204    Free PMC article.
Highly Cited.
Network-based support vector machine for classification of microarray samples.
Yanni Zhu, Xiaotong Shen, Wei Pan.
BMC Bioinformatics, 2009 Feb 28; 10 Suppl 1. PMID: 19208121    Free PMC article.
Master regulators used as breast cancer metastasis classifier.
Wei Keat Lim, Eugenia Lyashenko, Andrea Califano.
Pac Symp Biocomput, 2009 Feb 13;. PMID: 19209726    Free PMC article.
A bayesian analysis strategy for cross-study translation of gene expression biomarkers.
Joseph Lucas, Carlos Carvalho, Mike West.
Stat Appl Genet Mol Biol, 2009 Feb 19; 8. PMID: 19222378    Free PMC article.
Cross-study projections of genomic biomarkers: an evaluation in cancer genomics.
Joseph E Lucas, Carlos M Carvalho, +2 authors, Mike West.
PLoS One, 2009 Feb 20; 4(2). PMID: 19225561    Free PMC article.
Learning therapeutic lessons from metastasis suppressor proteins.
Steven Christopher Smith, Dan Theodorescu.
Nat Rev Cancer, 2009 Feb 27; 9(4). PMID: 19242414    Free PMC article.
Review.
Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue.
Dung-Tsa Chen, Aejaz Nasir, +12 authors, Timothy Yeatman.
Breast Cancer Res Treat, 2009 Mar 07; 119(2). PMID: 19266279    Free PMC article.
A radiation-derived gene expression signature predicts clinical outcome for breast cancer patients.
Brian D Piening, Pei Wang, Aravind Subramanian, Amanda G Paulovich.
Radiat Res, 2009 Mar 10; 171(2). PMID: 19267539    Free PMC article.
Meta-analysis and gene set enrichment relative to er status reveal elevated activity of MYC and E2F in the "basal" breast cancer subgroup.
M Chehani Alles, Margaret Gardiner-Garden, +5 authors, Christopher J Ormandy.
PLoS One, 2009 Mar 10; 4(3). PMID: 19270750    Free PMC article.
T-cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers.
Achim Rody, Uwe Holtrich, +10 authors, Manfred Kaufmann.
Breast Cancer Res, 2009 Mar 11; 11(2). PMID: 19272155    Free PMC article.
Highly Cited.
Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells.
Marta Santisteban, Jennifer M Reiman, +10 authors, Keith L Knutson.
Cancer Res, 2009 Mar 12; 69(7). PMID: 19276366    Free PMC article.
Highly Cited.
A compact VEGF signature associated with distant metastases and poor outcomes.
Zhiyuan Hu, Cheng Fan, +10 authors, Charles M Perou.
BMC Med, 2009 Mar 18; 7. PMID: 19291283    Free PMC article.
Derivation of molecular signatures for breast cancer recurrence prediction using a two-way validation approach.
Yijun Sun, Virginia Urquidi, Steve Goodison.
Breast Cancer Res Treat, 2009 Mar 18; 119(3). PMID: 19291396    Free PMC article.
No evidence of familial correlation in breast cancer metastasis.
Alice S Whittemore, Beth Stearman, +5 authors, Saundra S Buys.
Breast Cancer Res Treat, 2009 Mar 20; 118(3). PMID: 19296215    Free PMC article.
Evaluation of malignancy-risk gene signature in breast cancer patients.
Dung-Tsa Chen, Aejaz Nasir, +3 authors, Timothy Yeatman.
Breast Cancer Res Treat, 2009 Mar 24; 120(1). PMID: 19306088    Free PMC article.
Identification of a putative protein profile associated with tamoxifen therapy resistance in breast cancer.
Arzu Umar, Hyuk Kang, +8 authors, Ljiljana Pasa-Tolić.
Mol Cell Proteomics, 2009 Mar 31; 8(6). PMID: 19329653    Free PMC article.
Mining metastasis related genes by primary-secondary tumor comparisons from large-scale databases.
Sangwoo Kim, Doheon Lee.
BMC Bioinformatics, 2009 Apr 15; 10 Suppl 3. PMID: 19344478    Free PMC article.
Distant metastasis: not out of reach any more.
François Bertucci, Daniel Birnbaum.
J Biol, 2009 Apr 07; 8(3). PMID: 19344492    Free PMC article.
Review.
Gene expression profiles and breast cancer metastasis: a genetic perspective.
Kent W Hunter, Jude Alsarraj.
Clin Exp Metastasis, 2009 Apr 07; 26(6). PMID: 19347591    Free PMC article.
Review.
Coactivator function defines the active estrogen receptor alpha cistrome.
Mathieu Lupien, Jérôme Eeckhoute, +4 authors, Myles Brown.
Mol Cell Biol, 2009 Apr 15; 29(12). PMID: 19364822    Free PMC article.
Gene expression profiling of human lymph node metastases and matched primary breast carcinomas: clinical implications.
Mika Suzuki, David Tarin.
Mol Oncol, 2007 Sep 01; 1(2). PMID: 19383293    Free PMC article.
The MINDACT trial: the first prospective clinical validation of a genomic tool.
Fatima Cardoso, Martine Piccart-Gebhart, +2 authors, TRANSBIG Consortium.
Mol Oncol, 2007 Dec 01; 1(3). PMID: 19383299    Free PMC article.
PrognoScan: a new database for meta-analysis of the prognostic value of genes.
Hideaki Mizuno, Kunio Kitada, Kenta Nakai, Akinori Sarai.
BMC Med Genomics, 2009 Apr 28; 2. PMID: 19393097    Free PMC article.
Highly Cited.
An expression module of WIPF1-coexpressed genes identifies patients with favorable prognosis in three tumor types.
Eike Staub, Joern Groene, +11 authors, André Rosenthal.
J Mol Med (Berl), 2009 Apr 29; 87(6). PMID: 19399471    Free PMC article.
A mouse mammary gland involution mRNA signature identifies biological pathways potentially associated with breast cancer metastasis.
Torsten Stein, Nathan Salomonis, +2 authors, Barry A Gusterson.
J Mammary Gland Biol Neoplasia, 2009 May 02; 14(2). PMID: 19408105
Review.
Recent advances in systemic therapy: new diagnostics and biological predictors of outcome in early breast cancer.
Catherine Oakman, Silvia Bessi, +3 authors, Angelo Di Leo.
Breast Cancer Res, 2009 May 14; 11(2). PMID: 19435470    Free PMC article.
Review.
The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer.
R Shah, P Smith, +5 authors, T Crook.
Br J Cancer, 2009 May 14; 100(10). PMID: 19436308    Free PMC article.
Systematic identification of transcription factors associated with patient survival in cancers.
Chao Cheng, Lei M Li, Pedro Alves, Mark Gerstein.
BMC Genomics, 2009 May 16; 10. PMID: 19442316    Free PMC article.
Mechanisms of bone metastases of breast cancer.
Larry J Suva, Robert J Griffin, Issam Makhoul.
Endocr Relat Cancer, 2009 May 16; 16(3). PMID: 19443538    Free PMC article.
Review.
Effects of sample size on robustness and prediction accuracy of a prognostic gene signature.
Seon-Young Kim.
BMC Bioinformatics, 2009 May 19; 10. PMID: 19445687    Free PMC article.
Evaluation of microarray preprocessing algorithms based on concordance with RT-PCR in clinical samples.
Balazs Gyorffy, Bela Molnar, +2 authors, Aron C Eklund.
PLoS One, 2009 May 23; 4(5). PMID: 19461970    Free PMC article.
Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer.
Roshan Agarwal, Ana-Maria Gonzalez-Angulo, +16 authors, Bryan T Hennessy.
Clin Cancer Res, 2009 May 28; 15(11). PMID: 19470724    Free PMC article.
Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment.
Denise A Chan, Tiara L A Kawahara, +3 authors, Amato J Giaccia.
Cancer Cell, 2009 May 30; 15(6). PMID: 19477431    Free PMC article.
Profile of estrogen-responsive genes in an estrogen-specific mammary gland outgrowth model.
Bonnie J Deroo, Sylvia C Hewitt, +3 authors, Kenneth S Korach.
Mol Reprod Dev, 2009 Jun 02; 76(8). PMID: 19484750    Free PMC article.
AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist.
Daniel R Rhodes, Bushra Ateeq, +13 authors, Arul M Chinnaiyan.
Proc Natl Acad Sci U S A, 2009 Jun 03; 106(25). PMID: 19487683    Free PMC article.
A systems biology view of cancer.
Reinhard Laubenbacher, Valerie Hower, +5 authors, Steven Akman.
Biochim Biophys Acta, 2009 Jun 10; 1796(2). PMID: 19505535    Free PMC article.
Review.
Clinical utility of microarrays: current status, existing challenges and future outlook.
Xinmin Li, Richard J Quigg, +3 authors, Elaine F Reed.
Curr Genomics, 2009 Jun 10; 9(7). PMID: 19506735    Free PMC article.
Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study.
Joëlle Vermeulen, Katleen De Preter, +33 authors, Jo Vandesompele.
Lancet Oncol, 2009 Jun 12; 10(7). PMID: 19515614    Free PMC article.
HtrA serine proteases as potential therapeutic targets in cancer.
Jeremy Chien, Mara Campioni, Viji Shridhar, Alfonso Baldi.
Curr Cancer Drug Targets, 2009 Jun 13; 9(4). PMID: 19519315    Free PMC article.
Review.
Genomic predictors of outcome and treatment response in breast cancer.
Lara Dunn, Angela Demichele.
Mol Diagn Ther, 2009 Jun 23; 13(2). PMID: 19537843
Review.
Prestige centrality-based functional outlier detection in gene expression analysis.
Ali Torkamani, Nicholas J Schork.
Bioinformatics, 2009 Jun 25; 25(17). PMID: 19549629    Free PMC article.
Gene expression profiling identifies activated growth factor signaling in poor prognosis (Luminal-B) estrogen receptor positive breast cancer.
Sherene Loi, Christos Sotiriou, +5 authors, Grant A McArthur.
BMC Med Genomics, 2009 Jun 26; 2. PMID: 19552798    Free PMC article.
Intrinsic bias in breast cancer gene expression data sets.
Jonathan D Mosley, Ruth A Keri.
BMC Cancer, 2009 Jul 01; 9. PMID: 19563679    Free PMC article.
Estrogen regulation of cyclin E2 requires cyclin D1 but not c-Myc.
C Elizabeth Caldon, C Marcelo Sergio, +4 authors, Elizabeth A Musgrove.
Mol Cell Biol, 2009 Jul 01; 29(17). PMID: 19564413    Free PMC article.
Latent bone metastasis in breast cancer tied to Src-dependent survival signals.
Xiang H-F Zhang, Qiongqing Wang, +5 authors, Joan Massagué.
Cancer Cell, 2009 Jul 04; 16(1). PMID: 19573813    Free PMC article.
Highly Cited.
Breast cancer subtypes based on ER/PR and Her2 expression: comparison of clinicopathologic features and survival.
Adedayo A Onitilo, Jessica M Engel, Robert T Greenlee, Bickol N Mukesh.
Clin Med Res, 2009 Jul 04; 7(1-2). PMID: 19574486    Free PMC article.
Highly Cited.
A systems biology-based gene expression classifier of glioblastoma predicts survival with solid tumors.
Jing Zhang, Bing Liu, +7 authors, Sonya Wei Song.
PLoS One, 2009 Jul 18; 4(7). PMID: 19609451    Free PMC article.
SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis.
Hailing Cheng, Pixu Liu, +9 authors, Jean J Zhao.
Sci Signal, 2009 Jul 23; 2(80). PMID: 19622832    Free PMC article.
CT-X antigen expression in human breast cancer.
Anita Grigoriadis, Otavia L Caballero, +11 authors, A Munro Neville.
Proc Natl Acad Sci U S A, 2009 Aug 05; 106(32). PMID: 19651608    Free PMC article.
Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells.
'Matladi N Ndlovu, Carine Van Lint, +4 authors, Wim Vanden Berghe.
Mol Cell Biol, 2009 Aug 19; 29(20). PMID: 19687301    Free PMC article.
Frequent loss of heterozygosity at the interferon regulatory factor-1 gene locus in breast cancer.
Luciane R Cavalli, Rebecca B Riggins, +2 authors, Bassem R Haddad.
Breast Cancer Res Treat, 2009 Aug 22; 121(1). PMID: 19697121    Free PMC article.
Biological determinants of endocrine resistance in breast cancer.
Elizabeth A Musgrove, Robert L Sutherland.
Nat Rev Cancer, 2009 Aug 25; 9(9). PMID: 19701242
Highly Cited. Review.
Antiestrogen-resistant subclones of MCF-7 human breast cancer cells are derived from a common monoclonal drug-resistant progenitor.
Kathryn R Coser, Ben S Wittner, +8 authors, Toshi Shioda.
Proc Natl Acad Sci U S A, 2009 Aug 27; 106(34). PMID: 19706540    Free PMC article.
Identification of novel gene amplifications in breast cancer and coexistence of gene amplification with an activating mutation of PIK3CA.
Mitsutaka Kadota, Misako Sato, +11 authors, Maxwell P Lee.
Cancer Res, 2009 Aug 27; 69(18). PMID: 19706770    Free PMC article.
The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor.
Nigel P S Crawford, Hailiu Yang, Katherine R Mattaini, Kent W Hunter.
J Biol Chem, 2009 Aug 28; 284(42). PMID: 19710015    Free PMC article.
Robust model selection for classification of microarrays.
Ikumi Suzuki, Takashi Takenouchi, +2 authors, Shin Ishii.
Cancer Inform, 2009 Sep 01; 7. PMID: 19718450    Free PMC article.
mRNA expression profiles show differential regulatory effects of microRNAs between estrogen receptor-positive and estrogen receptor-negative breast cancer.
Chao Cheng, Xuping Fu, Pedro Alves, Mark Gerstein.
Genome Biol, 2009 Sep 03; 10(9). PMID: 19723326    Free PMC article.
Improvement of the clinical applicability of the Genomic Grade Index through a qRT-PCR test performed on frozen and formalin-fixed paraffin-embedded tissues.
Jérôme Toussaint, Anieta M Sieuwerts, +8 authors, Christos Sotiriou.
BMC Genomics, 2009 Sep 12; 10. PMID: 19744330    Free PMC article.
Genetic characterization of breast cancer and implications for clinical management.
Felipe C Geyer, Maria A Lopez-Garcia, Maryou B Lambros, Jorge S Reis-Filho.
J Cell Mol Med, 2009 Sep 17; 13(10). PMID: 19754664    Free PMC article.
Review.
The rapamycin-regulated gene expression signature determines prognosis for breast cancer.
Argun Akcakanat, Li Zhang, Spiridon Tsavachidis, Funda Meric-Bernstam.
Mol Cancer, 2009 Sep 26; 8. PMID: 19778445    Free PMC article.
Chemotherapy: Adjuvant chemotherapy in older patients with breast cancer.
Agnes Jager, Jaap Verweij, Stefan Sleijfer.
Nat Rev Clin Oncol, 2009 Sep 30; 6(10). PMID: 19786999
Immutable functional attributes of histologic grade revealed by context-independent gene expression in primary breast cancer cells.
Shanaz H Dairkee, Aejaz Sayeed, +6 authors, Dan H Moore.
Cancer Res, 2009 Oct 01; 69(19). PMID: 19789341    Free PMC article.
Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model.
Anka Bric, Cornelius Miething, +12 authors, Scott W Lowe.
Cancer Cell, 2009 Oct 06; 16(4). PMID: 19800577    Free PMC article.
Identification of novel kinase targets for the treatment of estrogen receptor-negative breast cancer.
Corey Speers, Anna Tsimelzon, +7 authors, Powel Brown.
Clin Cancer Res, 2009 Oct 08; 15(20). PMID: 19808870    Free PMC article.
Novel expression signatures identified by transcriptional analysis of separated leucocyte subsets in systemic lupus erythematosus and vasculitis.
Paul A Lyons, Eoin F McKinney, +7 authors, Kenneth G C Smith.
Ann Rheum Dis, 2009 Oct 10; 69(6). PMID: 19815495    Free PMC article.
KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta.
Dung-Fang Lee, Hsu-Ping Kuo, +16 authors, Mien-Chie Hung.
Mol Cell, 2009 Oct 13; 36(1). PMID: 19818716    Free PMC article.
Highly Cited.
Preinvasive breast cancer.
Dennis C Sgroi.
Annu Rev Pathol, 2009 Oct 15; 5. PMID: 19824828    Free PMC article.
Review.
Gene expression profile assays as predictors of distant recurrence-free survival in early-stage breast cancer.
Nicole M Kuderer, Gary H Lyman.
Cancer Invest, 2009 Oct 17; 27(9). PMID: 19832034    Free PMC article.
Review.
Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis.
Adrian M Jubb, Francesca M Buffa, Adrian L Harris.
J Cell Mol Med, 2009 Oct 21; 14(1-2). PMID: 19840191    Free PMC article.
Review.
Can survival prediction be improved by merging gene expression data sets?
Haleh Yasrebi, Peter Sperisen, Viviane Praz, Philipp Bucher.
PLoS One, 2009 Oct 24; 4(10). PMID: 19851466    Free PMC article.
Circulating levels of matrix metalloproteinase-9 (MMP-9), neutrophil gelatinase-associated lipocalin (NGAL) and their complex MMP-9/NGAL in breast cancer disease.
Xeni Provatopoulou, Antonia Gounaris, +6 authors, George Zografos.
BMC Cancer, 2009 Nov 06; 9. PMID: 19889214    Free PMC article.
Altered serotonin physiology in human breast cancers favors paradoxical growth and cell survival.
Vaibhav P Pai, Aaron M Marshall, +2 authors, Nelson D Horseman.
Breast Cancer Res, 2009 Nov 12; 11(6). PMID: 19903352    Free PMC article.
CITED2 and NCOR2 in anti-oestrogen resistance and progression of breast cancer.
T van Agthoven, A M Sieuwerts, +9 authors, L C J Dorssers.
Br J Cancer, 2009 Nov 12; 101(11). PMID: 19904269    Free PMC article.
Prediction of outcome of patients with metastatic breast cancer: evaluation with prognostic factors and Nottingham prognostic index.
Mu-Tai Liu, Wen-Tao Huang, +5 authors, Hao-Han Yang.
Support Care Cancer, 2009 Nov 12; 18(12). PMID: 19904562
Epithelial to mesenchymal transition and breast cancer.
Eva Tomaskovic-Crook, Erik W Thompson, Jean Paul Thiery.
Breast Cancer Res, 2009 Nov 17; 11(6). PMID: 19909494    Free PMC article.
Highly Cited. Review.
Impact of biospecimens handling on biomarker research in breast cancer.
Loris De Cecco, Valeria Musella, +6 authors, Maria Grazia Daidone.
BMC Cancer, 2009 Nov 26; 9. PMID: 19930681    Free PMC article.
A comprehensive sensitivity analysis of microarray breast cancer classification under feature variability.
Herman M J Sontrop, Perry D Moerland, +2 authors, Wim F J Verhaegh.
BMC Bioinformatics, 2009 Nov 28; 10. PMID: 19941644    Free PMC article.
Histological and molecular types of breast cancer: is there a unifying taxonomy?
Britta Weigelt, Jorge S Reis-Filho.
Nat Rev Clin Oncol, 2009 Nov 28; 6(12). PMID: 19942925
Highly Cited. Review.
Accurate and reliable cancer classification based on probabilistic inference of pathway activity.
Junjie Su, Byung-Jun Yoon, Edward R Dougherty.
PLoS One, 2009 Dec 10; 4(12). PMID: 19997592    Free PMC article.
Survival prediction from clinico-genomic models--a comparative study.
Hege M Bøvelstad, Ståle Nygård, Ornulf Borgan.
BMC Bioinformatics, 2009 Dec 17; 10. PMID: 20003386    Free PMC article.
Web-based interrogation of gene expression signatures using EXALT.
Jun Wu, Qingchao Qiu, +5 authors, Yajun Yi.
BMC Bioinformatics, 2009 Dec 17; 10. PMID: 20003458    Free PMC article.
Expression signature developed from a complex series of mouse models accurately predicts human breast cancer survival.
Mei He, David P Mangiameli, +5 authors, Steven K Libutti.
Clin Cancer Res, 2009 Dec 24; 16(1). PMID: 20028755    Free PMC article.
Current potential and limitations of molecular diagnostic methods in head and neck cancer.
Magdy E Mahfouz, Juan P Rodrigo, +4 authors, Alfio Ferlito.
Eur Arch Otorhinolaryngol, 2009 Dec 29; 267(6). PMID: 20037788
Review.
Correlating measurements across samples improves accuracy of large-scale expression profile experiments.
Mariano Javier Alvarez, Pavel Sumazin, Presha Rajbhandari, Andrea Califano.
Genome Biol, 2010 Jan 01; 10(12). PMID: 20042104    Free PMC article.
Classification across gene expression microarray studies.
Andreas Buness, Markus Ruschhaupt, Ruprecht Kuner, Achim Tresch.
BMC Bioinformatics, 2010 Jan 01; 10. PMID: 20042109    Free PMC article.
Detecting disease associated modules and prioritizing active genes based on high throughput data.
Yu-Qing Qiu, Shihua Zhang, Xiang-Sun Zhang, Luonan Chen.
BMC Bioinformatics, 2010 Jan 15; 11. PMID: 20070902    Free PMC article.
Multidisciplinary approach of early breast cancer: the biology applied to radiation oncology.
Céline Bourgier, Mahmut Ozsahin, David Azria.
Radiat Oncol, 2010 Jan 16; 5. PMID: 20074364    Free PMC article.
Review.
Multi-platform whole-genome microarray analyses refine the epigenetic signature of breast cancer metastasis with gene expression and copy number.
Joseph Andrews, Wendy Kennette, +4 authors, David I Rodenhiser.
PLoS One, 2010 Jan 20; 5(1). PMID: 20084286    Free PMC article.
Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer.
Yang Li, Lihua Zou, +9 authors, Zhigang Charles Wang.
Nat Med, 2010 Jan 26; 16(2). PMID: 20098429    Free PMC article.
Highly Cited.
Simpler evaluation of predictions and signature stability for gene expression data.
Yvonne E Pittelkow, Susan R Wilson.
J Biomed Biotechnol, 2010 Jan 30; 2009. PMID: 20111740    Free PMC article.
Biomarker profile in breast carcinomas presenting with bone metastasis.
Olga L Bohn, Irem Nasir, +4 authors, Mamatha Chivukula.
Int J Clin Exp Pathol, 2010 Feb 04; 3(2). PMID: 20126581    Free PMC article.
A population-based gene signature is predictive of breast cancer survival and chemoresponse.
Shruti Rathnagiriswaran, Ying-Wooi Wan, +3 authors, Nancy L Guo.
Int J Oncol, 2010 Feb 04; 36(3). PMID: 20126981    Free PMC article.
MYC regulation of a "poor-prognosis" metastatic cancer cell state.
Anita Wolfer, Ben S Wittner, +14 authors, Sridhar Ramaswamy.
Proc Natl Acad Sci U S A, 2010 Feb 06; 107(8). PMID: 20133671    Free PMC article.
Molecular risk assessment of BIG 1-98 participants by expression profiling using RNA from archival tissue.
Janine Antonov, Vlad Popovici, +9 authors, Rolf Jaggi.
BMC Cancer, 2010 Feb 11; 10. PMID: 20144231    Free PMC article.
Cellular processes of v-Src transformation revealed by gene profiling of primary cells--implications for human cancer.
Bart M Maślikowski, Benjamin D Néel, +4 authors, Pierre-André Bédard.
BMC Cancer, 2010 Feb 16; 10. PMID: 20152043    Free PMC article.
Have the roles of two functional polymorphisms in breast cancer, R72P in P53 and MDM2-309 in MDM2, become clearer?
Rodney J Scott.
Breast Cancer Res, 2010 Feb 17; 12(1). PMID: 20156327    Free PMC article.
A fuzzy gene expression-based computational approach improves breast cancer prognostication.
Benjamin Haibe-Kains, Christine Desmedt, +3 authors, Gianluca Bontempi.
Genome Biol, 2010 Feb 17; 11(2). PMID: 20156340    Free PMC article.
Bimodal gene expression patterns in breast cancer.
Marina Bessarabova, Eugene Kirillov, +3 authors, Tatiana Nikolskaya.
BMC Genomics, 2010 Mar 03; 11 Suppl 1. PMID: 20158879    Free PMC article.
Approaches to biomarkers in human colorectal cancer: looking back, to go forward.
Rod K Nibbe, Mark R Chance.
Biomark Med, 2010 Feb 18; 3(4). PMID: 20161020    Free PMC article.
Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer.
C Elizabeth Caldon, Elizabeth A Musgrove.
Cell Div, 2010 Feb 26; 5. PMID: 20180967    Free PMC article.
Gene expression profiles identify inflammatory signatures in dendritic cells.
Anna Torri, Ottavio Beretta, +3 authors, Maria Foti.
PLoS One, 2010 Mar 03; 5(2). PMID: 20195376    Free PMC article.
Pathway-BasedFeature Selection Algorithm for Cancer Microarray Data.
Nirmalya Bandyopadhyay, Tamer Kahveci, +2 authors, Sanjay Ranka.
Adv Bioinformatics, 2009 Jan 01;. PMID: 20204186    Free PMC article.
The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer.
Zhi Hu, Ge Huang, +7 authors, Jian-Hua Mao.
Breast Cancer Res, 2010 Mar 10; 12(2). PMID: 20211017    Free PMC article.
Identifying common prognostic factors in genomic cancer studies: a novel index for censored outcomes.
Sigrid Rouam, Thierry Moreau, Philippe Broët.
BMC Bioinformatics, 2010 Mar 26; 11. PMID: 20334636    Free PMC article.
A pathway-based classification of human breast cancer.
Michael L Gatza, Joseph E Lucas, +8 authors, Joseph R Nevins.
Proc Natl Acad Sci U S A, 2010 Mar 26; 107(15). PMID: 20335537    Free PMC article.
Highly Cited.
Protein interaction network underpins concordant prognosis among heterogeneous breast cancer signatures.
James Chen, Lee Sam, +5 authors, Yves A Lussier.
J Biomed Inform, 2010 Mar 31; 43(3). PMID: 20350617    Free PMC article.
Expression of Long-chain Fatty Acyl-CoA Synthetase 4 in Breast and Prostate Cancers Is Associated with Sex Steroid Hormone Receptor Negativity.
Marie E Monaco, Chad J Creighton, +3 authors, Diana M Stafforini.
Transl Oncol, 2010 Apr 03; 3(2). PMID: 20360933    Free PMC article.
Support Vector Machines with Disease-gene-centric Network Penalty for High Dimensional Microarray Data.
Yanni Zhu, Wei Pan, Xiaotong Shen.
Stat Interface, 2010 Apr 20; 2(3). PMID: 20401316    Free PMC article.
Improved microarray-based decision support with graph encoded interactome data.
Anneleen Daemen, Marco Signoretto, +2 authors, Bart De Moor.
PLoS One, 2010 Apr 27; 5(4). PMID: 20419106    Free PMC article.
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU.
Elena Favaro, Anassuya Ramachandran, +14 authors, Adrian L Harris.
PLoS One, 2010 May 04; 5(4). PMID: 20436681    Free PMC article.
Highly Cited.
Histological types of breast cancer: how special are they?
Britta Weigelt, Felipe C Geyer, Jorge S Reis-Filho.
Mol Oncol, 2010 May 11; 4(3). PMID: 20452298    Free PMC article.
Highly Cited. Review.
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.
Peter Bouwman, Amal Aly, +17 authors, Jos Jonkers.
Nat Struct Mol Biol, 2010 May 11; 17(6). PMID: 20453858    Free PMC article.
Highly Cited.
Protein-protein interaction reveals synergistic discrimination of cancer phenotype.
Jianghui Xiong, Juan Liu, +2 authors, Shanguang Chen.
Cancer Inform, 2010 May 12; 9. PMID: 20458363    Free PMC article.
Molecular basis for therapy resistance.
Per E Lønning.
Mol Oncol, 2010 May 15; 4(3). PMID: 20466604    Free PMC article.
Review.
An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer.
Raj Chari, Bradley P Coe, +2 authors, Wan L Lam.
BMC Syst Biol, 2010 May 19; 4. PMID: 20478067    Free PMC article.
Comparison of scores for bimodality of gene expression distributions and genome-wide evaluation of the prognostic relevance of high-scoring genes.
Birte Hellwig, Jan G Hengstler, +3 authors, Jörg Rahnenführer.
BMC Bioinformatics, 2010 May 27; 11. PMID: 20500820    Free PMC article.
Prediction of breast cancer prognosis using gene set statistics provides signature stability and biological context.
Gad Abraham, Adam Kowalczyk, +2 authors, Justin Zobel.
BMC Bioinformatics, 2010 May 27; 11. PMID: 20500821    Free PMC article.
Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer.
Adam C Pond, Jason I Herschkowitz, +9 authors, Jeffrey M Rosen.
Cancer Res, 2010 May 27; 70(12). PMID: 20501844    Free PMC article.
An eScience-Bayes strategy for analyzing omics data.
Martin Eklund, Ola Spjuth, Jarl E S Wikberg.
BMC Bioinformatics, 2010 May 28; 11. PMID: 20504364    Free PMC article.
Co-expression module analysis reveals biological processes, genomic gain, and regulatory mechanisms associated with breast cancer progression.
Zhiao Shi, Catherine K Derow, Bing Zhang.
BMC Syst Biol, 2010 May 29; 4. PMID: 20507583    Free PMC article.
Differential co-expression framework to quantify goodness of biclusters and compare biclustering algorithms.
Burton Kuan Hui Chia, R Krishna Murthy Karuturi.
Algorithms Mol Biol, 2010 May 29; 5. PMID: 20507637    Free PMC article.
Up-regulation of cell cycle arrest protein BTG2 correlates with increased overall survival in breast cancer, as detected by immunohistochemistry using tissue microarray.
Elin Möllerström, Anikó Kovács, +8 authors, Khalil Helou.
BMC Cancer, 2010 Jun 18; 10. PMID: 20553615    Free PMC article.
Immune signatures predict prognosis in localized cancer.
David S Hsu, Mickey K Kim, +7 authors, Phillip G Febbo.
Cancer Invest, 2010 Jun 24; 28(7). PMID: 20569070    Free PMC article.
Robust multi-tissue gene panel for cancer detection.
Joseph Irgon, C Chris Huang, +3 authors, Sándor Szalma.
BMC Cancer, 2010 Jun 24; 10. PMID: 20569444    Free PMC article.
Dynamic changes in gene expression in vivo predict prognosis of tamoxifen-treated patients with breast cancer.
Karen J Taylor, Andrew H Sims, +8 authors, Simon P Langdon.
Breast Cancer Res, 2010 Jun 24; 12(3). PMID: 20569502    Free PMC article.
Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer.
Chad J Creighton, Xiaoyong Fu, +11 authors, Rachel Schiff.
Breast Cancer Res, 2010 Jun 24; 12(3). PMID: 20569503    Free PMC article.
Highly Cited.
Role of thioredoxin reductase 1 and thioredoxin interacting protein in prognosis of breast cancer.
Cristina Cadenas, Dennis Franckenstein, +14 authors, Jan G Hengstler.
Breast Cancer Res, 2010 Jun 30; 12(3). PMID: 20584310    Free PMC article.
The embryonic transcription cofactor LBH is a direct target of the Wnt signaling pathway in epithelial development and in aggressive basal subtype breast cancers.
Megan E Rieger, Andrew H Sims, +2 authors, Karoline J Briegel.
Mol Cell Biol, 2010 Jul 08; 30(17). PMID: 20606007    Free PMC article.
The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer.
J Yu, Q Cao, +13 authors, A M Chinnaiyan.
Oncogene, 2010 Jul 14; 29(39). PMID: 20622896    Free PMC article.
Gene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy.
Ramón García-Escudero, Ana B Martínez-Cruz, +8 authors, Jesús M Paramio.
Mol Cancer, 2010 Jul 16; 9. PMID: 20630075    Free PMC article.
Local-learning-based feature selection for high-dimensional data analysis.
Yijun Sun, Sinisa Todorovic, Steve Goodison.
IEEE Trans Pattern Anal Mach Intell, 2010 Jul 17; 32(9). PMID: 20634556    Free PMC article.
Ceramide galactosyltransferase (UGT8) is a molecular marker of breast cancer malignancy and lung metastases.
P Dzięgiel, T Owczarek, +6 authors, M Ugorski.
Br J Cancer, 2010 Jul 22; 103(4). PMID: 20648017    Free PMC article.
Predictive relevance of HOXB13 protein expression for tamoxifen benefit in breast cancer.
Piiha-Lotta Jerevall, Agneta Jansson, +3 authors, Olle Stål.
Breast Cancer Res, 2010 Jul 24; 12(4). PMID: 20649975    Free PMC article.
Statistical methods for integrating multiple types of high-throughput data.
Yang Xie, Chul Ahn.
Methods Mol Biol, 2010 Jul 24; 620. PMID: 20652519    Free PMC article.
Review.
Molecular diversity in ductal carcinoma in situ (DCIS) and early invasive breast cancer.
Aslaug Aamodt Muggerud, Michael Hallett, +8 authors, Fredrik Wärnberg.
Mol Oncol, 2010 Jul 29; 4(4). PMID: 20663721    Free PMC article.
In silico estimates of tissue components in surgical samples based on expression profiling data.
Yipeng Wang, Xiao-Qin Xia, +5 authors, Michael McClelland.
Cancer Res, 2010 Jul 29; 70(16). PMID: 20663908    Free PMC article.
Robust prediction of t-year survival with data from multiple studies.
Tianxi Cai, Thomas A Gerds, Yingye Zheng, Jinbo Chen.
Biometrics, 2010 Jul 31; 67(2). PMID: 20670303    Free PMC article.
Increased entropy of signal transduction in the cancer metastasis phenotype.
Andrew E Teschendorff, Simone Severini.
BMC Syst Biol, 2010 Aug 03; 4. PMID: 20673354    Free PMC article.
Grouping pursuit through a regularization solution surface.
Xiaotong Shen, Hsin-Cheng Huang.
J Am Stat Assoc, 2010 Aug 07; 105(490). PMID: 20689721    Free PMC article.
Genomic index of sensitivity to endocrine therapy for breast cancer.
W Fraser Symmans, Christos Hatzis, +13 authors, Lajos Pusztai.
J Clin Oncol, 2010 Aug 11; 28(27). PMID: 20697068    Free PMC article.
Highly Cited.
Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
Geoff S Higgins, Adrian L Harris, +3 authors, Francesca M Buffa.
Oncotarget, 2010 Aug 12; 1(3). PMID: 20700469    Free PMC article.
ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments.
Alexander Lachmann, Huilei Xu, +3 authors, Avi Ma'ayan.
Bioinformatics, 2010 Aug 17; 26(19). PMID: 20709693    Free PMC article.
Highly Cited.
Enumerating the gene sets in breast cancer, a "direct" alternative to hierarchical clustering.
Dwain Mefford, Joel A Mefford.
BMC Genomics, 2010 Aug 25; 11. PMID: 20731868    Free PMC article.
Future directions of bone-targeted therapy for metastatic breast cancer.
Tomifumi Onishi, Naoki Hayashi, +2 authors, Naoto T Ueno.
Nat Rev Clin Oncol, 2010 Sep 03; 7(11). PMID: 20808302
Review.
EGFR signaling in breast cancer: bad to the bone.
John Foley, Nicole K Nickerson, +4 authors, David J Riese.
Semin Cell Dev Biol, 2010 Sep 04; 21(9). PMID: 20813200    Free PMC article.
Review.
Aberrant expression of LMO4 induces centrosome amplification and mitotic spindle abnormalities in breast cancer cells.
Marjorie E Montañez-Wiscovich, Melissa D Shelton, +6 authors, Ruth A Keri.
J Pathol, 2010 Sep 04; 222(3). PMID: 20814902    Free PMC article.
Inferring cancer subnetwork markers using density-constrained biclustering.
Phuong Dao, Recep Colak, +4 authors, Martin Ester.
Bioinformatics, 2010 Sep 09; 26(18). PMID: 20823331    Free PMC article.
Perspectives on Breast Cancer Management: Tailoring Treatment to the Individual Patient.
Christoph Thomssen.
Breast Care (Basel), 2008 Jan 01; 3(s1). PMID: 20824005    Free PMC article.
Assessment of Urokinase-Type Plasminogen Activator and Its Inhibitor PAI-1 in Breast Cancer Tissue: Historical Aspects and Future Prospects.
Manfred Schmitt, Karin Mengele, +4 authors, Nadia Harbeck.
Breast Care (Basel), 2008 Jan 01; 3(s2). PMID: 20824007    Free PMC article.
Genomic distance entrained clustering and regression modelling highlights interacting genomic regions contributing to proliferation in breast cancer.
Tim J Dexter, David Sims, +4 authors, Marketa Zvelebil.
BMC Syst Biol, 2010 Sep 10; 4. PMID: 20825665    Free PMC article.
Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA.
Julia Ling-Yu Chen, Daniel Merl, +7 authors, Jen-Tsan Chi.
PLoS Genet, 2010 Sep 17; 6(9). PMID: 20844768    Free PMC article.
Triple-negative, basal-like, and quintuple-negative breast cancers: better prediction model for survival.
Yoon-La Choi, Ensel Oh, +12 authors, Young Kee Shin.
BMC Cancer, 2010 Sep 24; 10. PMID: 20860845    Free PMC article.
ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2.
Ekaterina V Kalashnikova, Alexey S Revenko, +6 authors, Hong-Wu Chen.
Cancer Res, 2010 Sep 25; 70(22). PMID: 20864510    Free PMC article.
Growth factor stimulation induces a distinct ER(alpha) cistrome underlying breast cancer endocrine resistance.
Mathieu Lupien, Clifford A Meyer, +8 authors, Myles Brown.
Genes Dev, 2010 Oct 05; 24(19). PMID: 20889718    Free PMC article.
Nuclear receptor coregulators as a new paradigm for therapeutic targeting.
Elaine Y Hsia, Michael L Goodson, +2 authors, Hong-Wu Chen.
Adv Drug Deliv Rev, 2010 Oct 12; 62(13). PMID: 20933027    Free PMC article.
Review.
Identification of diagnostic subnetwork markers for cancer in human protein-protein interaction network.
Junjie Su, Byung-Jun Yoon, Edward R Dougherty.
BMC Bioinformatics, 2010 Oct 22; 11 Suppl 6. PMID: 20946619    Free PMC article.
A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer.
Christina Yau, Laura Esserman, +3 authors, Christopher C Benz.
Breast Cancer Res, 2010 Oct 16; 12(5). PMID: 20946665    Free PMC article.
Proteomic characterization of Her2/neu-overexpressing breast cancer cells.
Hexin Chen, Genaro Pimienta, +8 authors, Akhilesh Pandey.
Proteomics, 2010 Oct 21; 10(21). PMID: 20960451    Free PMC article.
Identification of high-quality cancer prognostic markers and metastasis network modules.
Jie Li, Anne E G Lenferink, +5 authors, Edwin Wang.
Nat Commun, 2010 Oct 27; 1. PMID: 20975711    Free PMC article.
Highly Cited.
Breast cancer in the personal genomics era.
Rachel E Ellsworth, David J Decewicz, Craig D Shriver, Darrell L Ellsworth.
Curr Genomics, 2010 Nov 03; 11(3). PMID: 21037853    Free PMC article.
Systems biology and genomics of breast cancer.
Charles M Perou, Anne-Lise Børresen-Dale.
Cold Spring Harb Perspect Biol, 2010 Nov 05; 3(2). PMID: 21047916    Free PMC article.
Review.
Improved prognostic classification of breast cancer defined by antagonistic activation patterns of immune response pathway modules.
Andrew E Teschendorff, Sergio Gomez, +4 authors, Carlos Caldas.
BMC Cancer, 2010 Nov 06; 10. PMID: 21050467    Free PMC article.
Multi-level reproducibility of signature hubs in human interactome for breast cancer metastasis.
Chen Yao, Hongdong Li, +3 authors, Zheng Guo.
BMC Syst Biol, 2010 Nov 10; 4. PMID: 21059271    Free PMC article.
The UCSC Cancer Genomics Browser: update 2011.
J Zachary Sanborn, Stephen C Benz, +12 authors, Jingchun Zhu.
Nucleic Acids Res, 2010 Nov 10; 39(Database issue). PMID: 21059681    Free PMC article.
Metastatic canine mammary carcinomas can be identified by a gene expression profile that partly overlaps with human breast cancer profiles.
Robert Klopfleisch, Dido Lenze, Michael Hummel, Achim D Gruber.
BMC Cancer, 2010 Nov 11; 10. PMID: 21062462    Free PMC article.
Node-Negative Breast Cancer: Which Patients Should Be Treated?
Marcus Schmidt.
Breast Care (Basel), 2008 Jan 01; 3(4). PMID: 21076603    Free PMC article.
Higher levels of GATA3 predict better survival in women with breast cancer.
Nam K Yoon, Erin L Maresh, +8 authors, Lee Goodglick.
Hum Pathol, 2010 Nov 17; 41(12). PMID: 21078439    Free PMC article.
Identification of a low-risk subgroup of HER-2-positive breast cancer by the 70-gene prognosis signature.
M Knauer, F Cardoso, +4 authors, L J van 't Veer.
Br J Cancer, 2010 Nov 18; 103(12). PMID: 21081926    Free PMC article.
Derivation of cancer diagnostic and prognostic signatures from gene expression data.
Steve Goodison, Yijun Sun, Virginia Urquidi.
Bioanalysis, 2010 Nov 19; 2(5). PMID: 21083217    Free PMC article.
Review.
Pre-clinical drug prioritization via prognosis-guided genetic interaction networks.
Jianghui Xiong, Juan Liu, +3 authors, Shanguang Chen.
PLoS One, 2010 Nov 19; 5(11). PMID: 21085674    Free PMC article.
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data.
Christoph Bartenhagen, Hans-Ulrich Klein, +2 authors, Martin Dugas.
BMC Bioinformatics, 2010 Nov 20; 11. PMID: 21087509    Free PMC article.
Predicting prognosis of breast cancer with gene signatures: are we lost in a sea of data?
Takayuki Iwamoto, Lajos Pusztai.
Genome Med, 2010 Nov 26; 2(11). PMID: 21092148    Free PMC article.
Diagnostic utility of snail in metaplastic breast carcinoma.
Aziza Nassar, Nicole Sookhan, +4 authors, Amy Degnim.
Diagn Pathol, 2010 Nov 30; 5. PMID: 21110878    Free PMC article.
Breast carcinomas arising at a young age: unique biology or a surrogate for aggressive intrinsic subtypes?
Carey K Anders, Cheng Fan, +4 authors, Charles M Perou.
J Clin Oncol, 2010 Dec 01; 29(1). PMID: 21115855    Free PMC article.
Nearest template prediction: a single-sample-based flexible class prediction with confidence assessment.
Yujin Hoshida.
PLoS One, 2010 Dec 03; 5(11). PMID: 21124904    Free PMC article.
The molecular pathology of breast cancer progression.
Alessandro Bombonati, Dennis C Sgroi.
J Pathol, 2010 Dec 03; 223(2). PMID: 21125683    Free PMC article.
Review.
The α₂β₁ integrin is a metastasis suppressor in mouse models and human cancer.
Norma E Ramirez, Zhonghua Zhang, +7 authors, Mary M Zutter.
J Clin Invest, 2010 Dec 08; 121(1). PMID: 21135504    Free PMC article.
Prognostic gene network modules in breast cancer hold promise.
Andrew E Teschendorff, Yan Jiao, Carlos Caldas.
Breast Cancer Res, 2010 Dec 15; 12(6). PMID: 21143771    Free PMC article.
Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium.
Dana M Brantley-Sieders, Charlene M Dunaway, +8 authors, Jin Chen.
Cancer Res, 2010 Dec 15; 71(3). PMID: 21148069    Free PMC article.
Minimising immunohistochemical false negative ER classification using a complementary 23 gene expression signature of ER status.
Qiyuan Li, Aron C Eklund, +5 authors, Charles Swanton.
PLoS One, 2010 Dec 15; 5(12). PMID: 21152022    Free PMC article.
Mesenchymal/stromal gene expression signature relates to basal-like breast cancers, identifies bone metastasis and predicts resistance to therapies.
Cristina Marchini, Maura Montani, +14 authors, Augusto Amici.
PLoS One, 2010 Dec 15; 5(11). PMID: 21152434    Free PMC article.
Trefoil factor 3 is oncogenic and mediates anti-estrogen resistance in human mammary carcinoma.
Nagarajan Kannan, Jian Kang, +10 authors, Peter E Lobie.
Neoplasia, 2010 Dec 21; 12(12). PMID: 21170268    Free PMC article.
Molecular profiling currently offers no more than tumour morphology and basic immunohistochemistry.
Britta Weigelt, Jorge S Reis-Filho.
Breast Cancer Res, 2011 Jan 05; 12 Suppl 4. PMID: 21172089    Free PMC article.
Manipulating protein acetylation in breast cancer: a promising approach in combination with hormonal therapies?
Aurélien Linares, Florence Dalenc, +2 authors, Vincent Cavailles.
J Biomed Biotechnol, 2010 Dec 29; 2011. PMID: 21188173    Free PMC article.
Review.
A systems biological approach to identify key transcription factors and their genomic neighborhoods in human sarcomas.
Antti Ylipää, Olli Yli-Harja, Wei Zhang, Matti Nykter.
Chin J Cancer, 2011 Jan 05; 30(1). PMID: 21192842    Free PMC article.
Metastasis suppressor genes at the interface between the environment and tumor cell growth.
Douglas R Hurst, Danny R Welch.
Int Rev Cell Mol Biol, 2011 Jan 05; 286. PMID: 21199781    Free PMC article.
Review.
Building prognostic models for breast cancer patients using clinical variables and hundreds of gene expression signatures.
Cheng Fan, Aleix Prat, +4 authors, Charles M Perou.
BMC Med Genomics, 2011 Jan 11; 4. PMID: 21214954    Free PMC article.
Young age, increased tumor proliferation and FOXM1 expression predict early metastatic relapse only for endocrine-dependent breast cancers.
Christina Yau, Yixin Wang, +2 authors, Christopher C Benz.
Breast Cancer Res Treat, 2011 Jan 13; 126(3). PMID: 21225456    Free PMC article.
HSulf-1 modulates FGF2- and hypoxia-mediated migration and invasion of breast cancer cells.
Ashwani Khurana, Peng Liu, +9 authors, Viji Shridhar.
Cancer Res, 2011 Jan 27; 71(6). PMID: 21266348    Free PMC article.
Paradoxical relationship between chromosomal instability and survival outcome in cancer.
Nicolai J Birkbak, Aron C Eklund, +7 authors, Charles Swanton.
Cancer Res, 2011 Jan 29; 71(10). PMID: 21270108    Free PMC article.
Highly Cited.
Calpain-mediated proteolysis of paxillin negatively regulates focal adhesion dynamics and cell migration.
Christa L Cortesio, Lindsy R Boateng, +2 authors, Anna Huttenlocher.
J Biol Chem, 2011 Jan 29; 286(12). PMID: 21270128    Free PMC article.
Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer.
Bao-Hong Guo, Yan Feng, +5 authors, Mu-Sheng Zeng.
Mol Cancer, 2011 Feb 01; 10(1). PMID: 21276221    Free PMC article.
Highly Cited.
Prolactin-induced mouse mammary carcinomas model estrogen resistant luminal breast cancer.
Lisa M Arendt, Debra E Rugowski, +3 authors, Linda A Schuler.
Breast Cancer Res, 2011 Feb 01; 13(1). PMID: 21276249    Free PMC article.
The effect of a DNA repair gene on cellular invasiveness: XRCC3 over-expression in breast cancer cells.
Veronica L Martinez-Marignac, Amélie Rodrigue, +6 authors, Raquel Aloyz.
PLoS One, 2011 Feb 02; 6(1). PMID: 21283680    Free PMC article.
Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis.
Haijun Zhang, Fanyan Meng, +6 authors, Guojun Wu.
Cancer Res, 2011 Feb 03; 71(4). PMID: 21285253    Free PMC article.
Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells.
Nilay Sethi, Xudong Dai, Christopher G Winter, Yibin Kang.
Cancer Cell, 2011 Feb 08; 19(2). PMID: 21295524    Free PMC article.
Highly Cited.
The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression.
Peter Chan, Andreas Möller, +11 authors, Stephen B Fox.
Breast Cancer Res, 2011 Feb 11; 13(1). PMID: 21306611    Free PMC article.
Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study.
Jack Cuzick, Gregory P Swanson, +18 authors, Transatlantic Prostate Group.
Lancet Oncol, 2011 Feb 12; 12(3). PMID: 21310658    Free PMC article.
Highly Cited.
The human DEK oncogene stimulates β-catenin signaling, invasion and mammosphere formation in breast cancer.
L M Privette Vinnedge, R McClaine, +3 authors, S I Wells.
Oncogene, 2011 Feb 15; 30(24). PMID: 21317931    Free PMC article.
Biomarkers in the age of omics: time for a systems biology approach.
Mones S Abu-Asab, Mohamed Chaouchi, +6 authors, Hakima Amri.
OMICS, 2011 Feb 16; 15(3). PMID: 21319991    Free PMC article.
High-resolution comparative genomic hybridization of inflammatory breast cancer and identification of candidate genes.
Ismahane Bekhouche, Pascal Finetti, +11 authors, François Bertucci.
PLoS One, 2011 Feb 23; 6(2). PMID: 21339811    Free PMC article.
Multi-resolution independent component analysis for high-performance tumor classification and biomarker discovery.
Henry Han, Xiao-Li Li.
BMC Bioinformatics, 2011 Mar 05; 12 Suppl 1. PMID: 21342590    Free PMC article.
Gene signatures of breast cancer progression and metastasis.
David I Rodenhiser, Joseph D Andrews, Theodore A Vandenberg, Ann F Chambers.
Breast Cancer Res, 2011 Feb 25; 13(1). PMID: 21345283    Free PMC article.
Review.
Effect of data combination on predictive modeling: a study using gene expression data.
Melanie Osl, Stephan Dreiseitl, +3 authors, Lucila Ohno-Machado.
AMIA Annu Symp Proc, 2011 Feb 25; 2010. PMID: 21347042    Free PMC article.
Gene expression profiles from formalin fixed paraffin embedded breast cancer tissue are largely comparable to fresh frozen matched tissue.
Lorenza Mittempergher, Jorma J de Ronde, +5 authors, Laura J Van't Veer.
PLoS One, 2011 Feb 25; 6(2). PMID: 21347257    Free PMC article.
ENCODE tiling array analysis identifies differentially expressed annotated and novel 5' capped RNAs in hepatitis C infected liver.
Milan E Folkers, Don A Delker, +4 authors, Curt H Hagedorn.
PLoS One, 2011 Mar 02; 6(2). PMID: 21359205    Free PMC article.
Can some patients avoid adjuvant chemotherapy for early-stage breast cancer?
Philippe L Bedard, Fatima Cardoso.
Nat Rev Clin Oncol, 2011 Mar 03; 8(5). PMID: 21364525
Review.
Emerging molecular biomarkers--blood-based strategies to detect and monitor cancer.
Samir M Hanash, Christina S Baik, Olli Kallioniemi.
Nat Rev Clin Oncol, 2011 Mar 03; 8(3). PMID: 21364687
Highly Cited. Review.
A signature inferred from Drosophila mitotic genes predicts survival of breast cancer patients.
Christian Damasco, Antonio Lembo, +3 authors, Paolo Provero.
PLoS One, 2011 Mar 10; 6(2). PMID: 21386884    Free PMC article.
Twist1-induced invadopodia formation promotes tumor metastasis.
Mark A Eckert, Thinzar M Lwin, +4 authors, Jing Yang.
Cancer Cell, 2011 Mar 15; 19(3). PMID: 21397860    Free PMC article.
Highly Cited.
Identification of novel variants of metadherin in breast cancer.
Xianqiang Liu, Ning Zhang, +7 authors, Qifeng Yang.
PLoS One, 2011 Mar 17; 6(3). PMID: 21408129    Free PMC article.
Microarray-based class discovery for molecular classification of breast cancer: analysis of interobserver agreement.
Alan Mackay, Britta Weigelt, +7 authors, Jorge S Reis-Filho.
J Natl Cancer Inst, 2011 Mar 23; 103(8). PMID: 21421860    Free PMC article.
Do two machine-learning based prognostic signatures for breast cancer capture the same biological processes?
Yotam Drier, Eytan Domany.
PLoS One, 2011 Mar 23; 6(3). PMID: 21423753    Free PMC article.
Combining gene signatures improves prediction of breast cancer survival.
Xi Zhao, Einar Andreas Rødland, +6 authors, Ole Christian Lingjærde.
PLoS One, 2011 Mar 23; 6(3). PMID: 21423775    Free PMC article.
Meta-analysis of gene expression microarrays with missing replicates.
Fan Shi, Gad Abraham, +2 authors, Adam Kowalczyk.
BMC Bioinformatics, 2011 Mar 26; 12. PMID: 21435268    Free PMC article.
GOBO: gene expression-based outcome for breast cancer online.
Markus Ringnér, Erik Fredlund, +2 authors, Johan Staaf.
PLoS One, 2011 Mar 30; 6(3). PMID: 21445301    Free PMC article.
Highly Cited.
Signaling pathways in breast cancer metastasis - novel insights from functional genomics.
Mario Andres Blanco, Yibin Kang.
Breast Cancer Res, 2011 Apr 05; 13(2). PMID: 21457525    Free PMC article.
Review.
Design and multiseries validation of a web-based gene expression assay for predicting breast cancer recurrence and patient survival.
Ryan K Van Laar.
J Mol Diagn, 2011 Apr 05; 13(3). PMID: 21458382    Free PMC article.
A signature of immune function genes associated with recurrence-free survival in breast cancer patients.
Maria Libera Ascierto, Maciej Kmieciak, +10 authors, Masoud H Manjili.
Breast Cancer Res Treat, 2011 Apr 12; 131(3). PMID: 21479927    Free PMC article.
CAERUS: predicting CAncER oUtcomeS using relationship between protein structural information, protein networks, gene expression data, and mutation data.
Kelvin Xi Zhang, B F Francis Ouellette.
PLoS Comput Biol, 2011 Apr 13; 7(3). PMID: 21483478    Free PMC article.
Breast cancer at bone metastatic sites: recent discoveries and treatment targets.
Osama Hussein, Svetlana V Komarova.
J Cell Commun Signal, 2011 Apr 13; 5(2). PMID: 21484191    Free PMC article.
Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization.
Kuo-Jang Kao, Kai-Ming Chang, Hui-Chi Hsu, Andrew T Huang.
BMC Cancer, 2011 Apr 20; 11. PMID: 21501481    Free PMC article.
Highly Cited.
An empirical Bayes' approach to joint analysis of multiple microarray gene expression studies.
Lingyan Ruan, Ming Yuan.
Biometrics, 2011 Apr 27; 67(4). PMID: 21517790    Free PMC article.
Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications.
Taru A Muranen, Dario Greco, +7 authors, Heli Nevanlinna.
Breast Cancer Res, 2011 May 06; 13(5). PMID: 21542898    Free PMC article.
ESR1 is co-expressed with closely adjacent uncharacterised genes spanning a breast cancer susceptibility locus at 6q25.1.
Anita K Dunbier, Helen Anderson, +8 authors, Mitch Dowsett.
PLoS Genet, 2011 May 10; 7(4). PMID: 21552322    Free PMC article.
Solving the puzzle of metastasis: the evolution of cell migration in neoplasms.
Jun Chen, Kathleen Sprouffske, Qihong Huang, Carlo C Maley.
PLoS One, 2011 May 11; 6(4). PMID: 21556134    Free PMC article.
A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.
Christos Hatzis, Lajos Pusztai, +27 authors, W Fraser Symmans.
JAMA, 2011 May 12; 305(18). PMID: 21558518    Free PMC article.
Highly Cited.
Receptor activator of NF-kB (RANK) expression in primary tumors associates with bone metastasis occurrence in breast cancer patients.
Daniele Santini, Gaia Schiavon, +16 authors, Giuseppe Tonini.
PLoS One, 2011 May 12; 6(4). PMID: 21559440    Free PMC article.
A multimarker QPCR-based platform for the detection of circulating tumour cells in patients with early-stage breast cancer.
T J Molloy, L A Devriese, +5 authors, L J van't Veer.
Br J Cancer, 2011 May 19; 104(12). PMID: 21587256    Free PMC article.
Biologic markers determine both the risk and the timing of recurrence in breast cancer.
Laura J Esserman, Dan H Moore, +11 authors, Christopher C Benz.
Breast Cancer Res Treat, 2011 May 21; 129(2). PMID: 21597921    Free PMC article.
The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors.
Lauren L C Marotta, Vanessa Almendro, +25 authors, Kornelia Polyak.
J Clin Invest, 2011 Jun 03; 121(7). PMID: 21633165    Free PMC article.
Highly Cited.
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies.
Brian D Lehmann, Joshua A Bauer, +4 authors, Jennifer A Pietenpol.
J Clin Invest, 2011 Jun 03; 121(7). PMID: 21633166    Free PMC article.
Highly Cited.
18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers.
Nicolaos Palaskas, Steven M Larson, +20 authors, Ingo K Mellinghoff.
Cancer Res, 2011 Jun 08; 71(15). PMID: 21646475    Free PMC article.
Domain and functional analysis of a novel breast tumor suppressor protein, SCUBE2.
Yuh-Charn Lin, Chun-Chuan Chen, Chien-Jui Cheng, Ruey-Bing Yang.
J Biol Chem, 2011 Jun 10; 286(30). PMID: 21652720    Free PMC article.
Combined genomic and phenotype screening reveals secretory factor SPINK1 as an invasion and survival factor associated with patient prognosis in breast cancer.
Wendy Weijia Soon, Lance David Miller, +7 authors, Edison T Liu.
EMBO Mol Med, 2011 Jun 10; 3(8). PMID: 21656687    Free PMC article.
Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse.
J Chuck Harrell, Aleix Prat, +6 authors, Charles M Perou.
Breast Cancer Res Treat, 2011 Jun 15; 132(2). PMID: 21671017    Free PMC article.
Highly Cited.
The changing role of pathology in breast cancer diagnosis and treatment.
Anthony S-Y Leong, Zhengping Zhuang.
Pathobiology, 2011 Jun 17; 78(2). PMID: 21677473    Free PMC article.
Review.
Impact of established prognostic factors and molecular subtype in very young breast cancer patients: pooled analysis of four EORTC randomized controlled trials.
Jos A van der Hage, J Sven D Mieog, +3 authors, Marc J van de Vijver.
Breast Cancer Res, 2011 Jun 28; 13(3). PMID: 21699739    Free PMC article.
Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell properties.
S M Farabaugh, D S Micalizzi, +2 authors, H L Ford.
Oncogene, 2011 Jun 28; 31(5). PMID: 21706047    Free PMC article.
Reversal of endocrine resistance in breast cancer: interrelationships among 14-3-3ζ, FOXM1, and a gene signature associated with mitosis.
Anna Bergamaschi, Barbara L Christensen, Benita S Katzenellenbogen.
Breast Cancer Res, 2011 Jun 29; 13(3). PMID: 21707964    Free PMC article.
Expression of endoplasmic reticulum stress proteins is a candidate marker of brain metastasis in both ErbB-2+ and ErbB-2- primary breast tumors.
Rebeca Sanz-Pamplona, Ramón Aragüés, +12 authors, Angels Sierra.
Am J Pathol, 2011 Jun 29; 179(2). PMID: 21708117    Free PMC article.
A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables.
David Endesfelder, Nicholas McGranahan, +4 authors, Charles Swanton.
Oncotarget, 2011 Jun 29; 2(7). PMID: 21709316    Free PMC article.
Systematic bias in genomic classification due to contaminating non-neoplastic tissue in breast tumor samples.
Fathi Elloumi, Zhiyuan Hu, +4 authors, Melissa A Troester.
BMC Med Genomics, 2011 Jul 02; 4. PMID: 21718502    Free PMC article.
Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas.
Gema Moreno-Bueno, Fernando Salvador, +14 authors, Amparo Cano.
EMBO Mol Med, 2011 Jul 07; 3(9). PMID: 21732535    Free PMC article.
Global microRNA expression profiling identifies MiR-210 associated with tumor proliferation, invasion and poor clinical outcome in breast cancer.
Françoise Rothé, Michail Ignatiadis, +9 authors, Christos Sotiriou.
PLoS One, 2011 Jul 09; 6(6). PMID: 21738599    Free PMC article.
Highly Cited.
Targeting androgen receptor in estrogen receptor-negative breast cancer.
Min Ni, Yiwen Chen, +6 authors, Myles Brown.
Cancer Cell, 2011 Jul 12; 20(1). PMID: 21741601    Free PMC article.
Highly Cited.
An evaluation protocol for subtype-specific breast cancer event prediction.
Herman M J Sontrop, Wim F J Verhaegh, Marcel J T Reinders, Perry D Moerland.
PLoS One, 2011 Jul 16; 6(7). PMID: 21760900    Free PMC article.
Contribution of xanthine oxidoreductase to mammary epithelial and breast cancer cell differentiation in part modulates inhibitor of differentiation-1.
Mehdi A Fini, Jenifer Monks, Susan M Farabaugh, Richard M Wright.
Mol Cancer Res, 2011 Jul 22; 9(9). PMID: 21775420    Free PMC article.
Kinome expression profiling and prognosis of basal breast cancers.
Renaud Sabatier, Pascal Finetti, +7 authors, François Bertucci.
Mol Cancer, 2011 Jul 23; 10. PMID: 21777462    Free PMC article.
The 'invisible hand': regulation of RHO GTPases by RHOGDIs.
Rafael Garcia-Mata, Etienne Boulter, Keith Burridge.
Nat Rev Mol Cell Biol, 2011 Jul 23; 12(8). PMID: 21779026    Free PMC article.
Highly Cited. Review.
Identification of the YES1 Kinase as a Therapeutic Target in Basal-Like Breast Cancers.
Erhan Bilal, Gabriela Alexe, +6 authors, Gyan Bhanot.
Genes Cancer, 2011 Jul 23; 1(10). PMID: 21779430    Free PMC article.
Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer.
Rebecca Roylance, David Endesfelder, +12 authors, Charles Swanton.
Cancer Epidemiol Biomarkers Prev, 2011 Jul 26; 20(10). PMID: 21784954    Free PMC article.
Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction.
Pierre-Emmanuel Colombo, Fernanda Milanezi, Britta Weigelt, Jorge S Reis-Filho.
Breast Cancer Res, 2011 Jul 27; 13(3). PMID: 21787441    Free PMC article.
Review.
Predictive and prognostic molecular markers for cancer medicine.
Sunali Mehta, Andrew Shelling, +4 authors, Cristin Print.
Ther Adv Med Oncol, 2010 Mar 01; 2(2). PMID: 21789130    Free PMC article.
Inhibition of matrix metalloproteinase 14 (MMP-14)-mediated cancer cell migration.
Kevin Zarrabi, Antoine Dufour, +7 authors, Jian Cao.
J Biol Chem, 2011 Jul 29; 286(38). PMID: 21795678    Free PMC article.
Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response.
Qiyuan Li, Aron C Eklund, +8 authors, Zoltan Szallasi.
BMC Bioinformatics, 2011 Jul 30; 12. PMID: 21798043    Free PMC article.
Inferring causal genomic alterations in breast cancer using gene expression data.
Linh M Tran, Bin Zhang, +6 authors, Jun Zhu.
BMC Syst Biol, 2011 Aug 03; 5. PMID: 21806811    Free PMC article.
Induction of stable drug resistance in human breast cancer cells using a combinatorial zinc finger transcription factor library.
Jeongeun Lee, Andrew S Hirsh, +9 authors, Dennis C Sgroi.
PLoS One, 2011 Aug 06; 6(7). PMID: 21818254    Free PMC article.
Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERα-positive breast cancer.
Sheryl R Krig, Seth Frietze, +9 authors, Colleen Sweeney.
Mol Cancer Res, 2011 Aug 09; 9(10). PMID: 21821674    Free PMC article.
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization.
Manav Korpal, Brian J Ell, +14 authors, Yibin Kang.
Nat Med, 2011 Aug 09; 17(9). PMID: 21822286    Free PMC article.
Highly Cited.
Histopathological and genomic grading provide complementary prognostic information in breast cancer: a study on publicly available datasets.
Nilotpal Chowdhury.
Patholog Res Int, 2011 Aug 17; 2011. PMID: 21845210    Free PMC article.
[Translational research in head and neck cancer. Biological characteristics and general aspects].
A Dietz, G Wichmann.
HNO, 2011 Aug 24; 59(9). PMID: 21861150
Review.
Activation of the glucocorticoid receptor is associated with poor prognosis in estrogen receptor-negative breast cancer.
Deng Pan, Masha Kocherginsky, Suzanne D Conzen.
Cancer Res, 2011 Aug 27; 71(20). PMID: 21868756    Free PMC article.
Highly Cited.
An integrative genomics approach to biomarker discovery in breast cancer.
Chindo Hicks, Rozana Asfour, Antonio Pannuti, Lucio Miele.
Cancer Inform, 2011 Aug 27; 10. PMID: 21869864    Free PMC article.
Challenges translating breast cancer gene signatures into the clinic.
Britta Weigelt, Lajos Pusztai, Alan Ashworth, Jorge S Reis-Filho.
Nat Rev Clin Oncol, 2011 Sep 01; 9(1). PMID: 21878891
Review.
Overexpression of centromere protein H is significantly associated with breast cancer progression and overall patient survival.
Wen-Ting Liao, Yan Feng, +4 authors, Li-Bing Song.
Chin J Cancer, 2011 Sep 02; 30(9). PMID: 21880184    Free PMC article.
GATA3 inhibits lysyl oxidase-mediated metastases of human basal triple-negative breast cancer cells.
I M Chu, A M Michalowski, +7 authors, J E Green.
Oncogene, 2011 Sep 06; 31(16). PMID: 21892208    Free PMC article.
Semi-supervised learning improves gene expression-based prediction of cancer recurrence.
Mingguang Shi, Bing Zhang.
Bioinformatics, 2011 Sep 07; 27(21). PMID: 21893520    Free PMC article.
Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasis.
V Walia, Y Yu, +8 authors, R C Elble.
Oncogene, 2011 Sep 13; 31(17). PMID: 21909135    Free PMC article.
Sprouty 2 is an independent prognostic factor in breast cancer and may be useful in stratifying patients for trastuzumab therapy.
Dana Faratian, Andrew H Sims, +4 authors, David J Harrison.
PLoS One, 2011 Sep 13; 6(8). PMID: 21909357    Free PMC article.
Postoperative serum proteomic profiles may predict recurrence-free survival in high-risk primary breast cancer.
Marie-Christine W Gast, Marc Zapatka, +7 authors, Jos H Beijnen.
J Cancer Res Clin Oncol, 2011 Sep 14; 137(12). PMID: 21913038    Free PMC article.
Breast cancer biological subtypes and protein expression predict for the preferential distant metastasis sites: a nationwide cohort study.
Harri Sihto, Johan Lundin, +9 authors, Heikki Joensuu.
Breast Cancer Res, 2011 Sep 15; 13(5). PMID: 21914172    Free PMC article.
Ischemia caused by time to freezing induces systematic microRNA and mRNA responses in cancer tissue.
Eldrid Borgan, Roy Navon, +6 authors, Anne-Lise Børresen-Dale.
Mol Oncol, 2011 Sep 16; 5(6). PMID: 21917534    Free PMC article.
Molecular characterization of the tumor-suppressive function of nischarin in breast cancer.
Somesh Baranwal, Yanfang Wang, +7 authors, Suresh K Alahari.
J Natl Cancer Inst, 2011 Sep 16; 103(20). PMID: 21917605    Free PMC article.
TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73.
Kang Liu, Shiyun Ling, Weei-Chin Lin.
Mol Cell Biol, 2011 Sep 21; 31(22). PMID: 21930790    Free PMC article.
Relationship between quantitative GRB7 RNA expression and recurrence after adjuvant anthracycline chemotherapy in triple-negative breast cancer.
Joseph A Sparano, Lori J Goldstein, +13 authors, Robert Gray.
Clin Cancer Res, 2011 Sep 22; 17(22). PMID: 21933890    Free PMC article.
A new gene expression signature, the ClinicoMolecular Triad Classification, may improve prediction and prognostication of breast cancer at the time of diagnosis.
Dong-Yu Wang, Susan J Done, +3 authors, Wey Liang Leong.
Breast Cancer Res, 2011 Sep 24; 13(5). PMID: 21939527    Free PMC article.
Top scoring pairs for feature selection in machine learning and applications to cancer outcome prediction.
Ping Shi, Surajit Ray, Qifu Zhu, Mark A Kon.
BMC Bioinformatics, 2011 Sep 24; 12. PMID: 21939564    Free PMC article.
The rearranged during transfection/papillary thyroid carcinoma tyrosine kinase is an estrogen-dependent gene required for the growth of estrogen receptor positive breast cancer cells.
Chunyu Wang, Julie Ann Mayer, Abhijit Mazumdar, Powel H Brown.
Breast Cancer Res Treat, 2011 Sep 29; 133(2). PMID: 21947652    Free PMC article.
Insight into the heterogeneity of breast cancer through next-generation sequencing.
Hege G Russnes, Nicholas Navin, James Hicks, Anne-Lise Borresen-Dale.
J Clin Invest, 2011 Oct 04; 121(10). PMID: 21965338    Free PMC article.
Highly Cited. Review.
Transglutaminase 2 facilitates the distant hematogenous metastasis of breast cancer by modulating interleukin-6 in cancer cells.
Keunhee Oh, Eunyoung Ko, +4 authors, Dong-Sup Lee.
Breast Cancer Res, 2011 Oct 05; 13(5). PMID: 21967801    Free PMC article.
A clinically relevant gene signature in triple negative and basal-like breast cancer.
Achim Rody, Thomas Karn, +11 authors, Manfred Kaufmann.
Breast Cancer Res, 2011 Oct 08; 13(5). PMID: 21978456    Free PMC article.
Highly Cited.
Protein networks as logic functions in development and cancer.
Janusz Dutkowski, Trey Ideker.
PLoS Comput Biol, 2011 Oct 08; 7(9). PMID: 21980275    Free PMC article.
Functional viability profiles of breast cancer.
Rachel Brough, Jessica R Frankum, +19 authors, Alan Ashworth.
Cancer Discov, 2011 Oct 11; 1(3). PMID: 21984977    Free PMC article.
Identifying cancer biomarkers by network-constrained support vector machines.
Li Chen, Jianhua Xuan, +2 authors, Yue Wang.
BMC Syst Biol, 2011 Oct 14; 5. PMID: 21992556    Free PMC article.
Quantifying stability in gene list ranking across microarray derived clinical biomarkers.
Sebastian Schneckener, Nilou S Arden, Andreas Schuppert.
BMC Med Genomics, 2011 Oct 15; 4. PMID: 21996057    Free PMC article.
DART: Denoising Algorithm based on Relevance network Topology improves molecular pathway activity inference.
Yan Jiao, Katherine Lawler, +6 authors, Andrew E Teschendorff.
BMC Bioinformatics, 2011 Oct 21; 12. PMID: 22011170    Free PMC article.
Network based consensus gene signatures for biomarker discovery in breast cancer.
Holger Fröhlich.
PLoS One, 2011 Nov 03; 6(10). PMID: 22046239    Free PMC article.
Molecular characterisation of formalin-fixed paraffin-embedded (FFPE) breast tumour specimens using a custom 512-gene breast cancer bead array-based platform.
M Abramovitz, B G Barwick, +8 authors, B Leyland-Jones.
Br J Cancer, 2011 Nov 10; 105(10). PMID: 22067903    Free PMC article.
The microenvironment in breast cancer progression: biology and implications for treatment.
Andrew E Place, Sung Jin Huh, Kornelia Polyak.
Breast Cancer Res, 2011 Nov 15; 13(6). PMID: 22078026    Free PMC article.
Highly Cited. Review.
Basal breast cancer: a complex and deadly molecular subtype.
F Bertucci, P Finetti, D Birnbaum.
Curr Mol Med, 2011 Nov 16; 12(1). PMID: 22082486    Free PMC article.
Review.
Novel staging system for predicting disease-specific survival in patients with breast cancer treated with surgery as the first intervention: time to modify the current American Joint Committee on Cancer staging system.
Min Yi, Elizabeth A Mittendorf, +10 authors, Kelly K Hunt.
J Clin Oncol, 2011 Nov 16; 29(35). PMID: 22084362    Free PMC article.
Biologic characteristics of premalignant breast disease.
Kimberly Cole, Maria Tabernero, Karen S Anderson.
Cancer Biomark, 2011 Nov 25; 9(1-6). PMID: 22112476    Free PMC article.
Multiple-input multiple-output causal strategies for gene selection.
Gianluca Bontempi, Benjamin Haibe-Kains, +2 authors, John Quackenbush.
BMC Bioinformatics, 2011 Nov 29; 12. PMID: 22118187    Free PMC article.
Role of Pirh2 in mediating the regulation of p53 and c-Myc.
Anne Hakem, Miyuki Bohgaki, +22 authors, Razqallah Hakem.
PLoS Genet, 2011 Nov 30; 7(11). PMID: 22125490    Free PMC article.
PBX1 genomic pioneer function drives ERα signaling underlying progression in breast cancer.
Luca Magnani, Elizabeth B Ballantyne, Xiaoyang Zhang, Mathieu Lupien.
PLoS Genet, 2011 Nov 30; 7(11). PMID: 22125492    Free PMC article.
Lack of sufficiently strong informative features limits the potential of gene expression analysis as predictive tool for many clinical classification problems.
Kenneth R Hess, Caimiao Wei, +3 authors, Lajos Pusztai.
BMC Bioinformatics, 2011 Dec 03; 12. PMID: 22132775    Free PMC article.
VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors.
Xin Lu, Euphemia Mu, +11 authors, Yibin Kang.
Cancer Cell, 2011 Dec 06; 20(6). PMID: 22137794    Free PMC article.
Highly Cited.
TRIM29 functions as a tumor suppressor in nontumorigenic breast cells and invasive ER+ breast cancer.
Jin Liu, Bryan Welm, +2 authors, Philip S Bernard.
Am J Pathol, 2011 Dec 06; 180(2). PMID: 22138580    Free PMC article.
Modeling invasive breast cancer: growth factors propel progression of HER2-positive premalignant lesions.
C-R Pradeep, A Zeisel, +15 authors, Y Yarden.
Oncogene, 2011 Dec 06; 31(31). PMID: 22139081    Free PMC article.
Identification of prognostic genes for recurrent risk prediction in triple negative breast cancer patients in Taiwan.
Lee H Chen, Wen-Hung Kuo, +7 authors, King-Jen Chang.
PLoS One, 2011 Dec 06; 6(11). PMID: 22140552    Free PMC article.
Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness.
Nyam-Osor Chimge, Sanjeev K Baniwal, +6 authors, Baruch Frenkel.
Clin Cancer Res, 2011 Dec 08; 18(3). PMID: 22147940    Free PMC article.
Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2.
Nyam-Osor Chimge, Sanjeev K Baniwal, +5 authors, Baruch Frenkel.
Breast Cancer Res, 2011 Dec 14; 13(6). PMID: 22151997    Free PMC article.
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.
Jessica D Kessler, Kristopher T Kahle, +24 authors, Thomas F Westbrook.
Science, 2011 Dec 14; 335(6066). PMID: 22157079    Free PMC article.
Highly Cited.
A simple but highly effective approach to evaluate the prognostic performance of gene expression signatures.
Maud H W Starmans, Glenn Fung, +2 authors, Philippe Lambin.
PLoS One, 2011 Dec 14; 6(12). PMID: 22163293    Free PMC article.
Selecting a single model or combining multiple models for microarray-based classifier development?--a comparative analysis based on large and diverse datasets generated from the MAQC-II project.
Minjun Chen, Leming Shi, +3 authors, Weida Tong.
BMC Bioinformatics, 2011 Dec 23; 12 Suppl 10. PMID: 22166133    Free PMC article.
A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells.
Kim J Png, Nils Halberg, Mitsukuni Yoshida, Sohail F Tavazoie.
Nature, 2011 Dec 16; 481(7380). PMID: 22170610
Highly Cited.
Variants on the promoter region of PTEN affect breast cancer progression and patient survival.
Tuomas Heikkinen, Dario Greco, +6 authors, Heli Nevanlinna.
Breast Cancer Res, 2011 Dec 17; 13(6). PMID: 22171747    Free PMC article.
Jetset: selecting the optimal microarray probe set to represent a gene.
Qiyuan Li, Nicolai J Birkbak, +2 authors, Aron C Eklund.
BMC Bioinformatics, 2011 Dec 17; 12. PMID: 22172014    Free PMC article.
Highly Cited.
A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression.
J N Anastas, T L Biechele, +4 authors, R T Moon.
Oncogene, 2011 Dec 20; 31(32). PMID: 22179838    Free PMC article.
Graph based fusion of miRNA and mRNA expression data improves clinical outcome prediction in prostate cancer.
Stephan Gade, Christine Porzelius, +6 authors, Tim Beissbarth.
BMC Bioinformatics, 2011 Dec 23; 12. PMID: 22188670    Free PMC article.
Early developments in gene-expression profiling of breast tumors: potential for increasing black-white patient disparities in breast cancer outcomes?
Donna H Odierna, Aimee Afable-Munsuz, +5 authors, Ninez A Ponce.
Per Med, 2011 Dec 23; 8(6). PMID: 22190978    Free PMC article.
YB-1, the E2F pathway, and regulation of tumor cell growth.
Annette Lasham, Weini Samuel, +10 authors, Antony W Braithwaite.
J Natl Cancer Inst, 2011 Dec 30; 104(2). PMID: 22205655    Free PMC article.
The influence of feature selection methods on accuracy, stability and interpretability of molecular signatures.
Anne-Claire Haury, Pierre Gestraud, Jean-Philippe Vert.
PLoS One, 2011 Dec 30; 6(12). PMID: 22205940    Free PMC article.
SLC22A5/OCTN2 expression in breast cancer is induced by estrogen via a novel intronic estrogen-response element (ERE).
Chunyu Wang, Ivan P Uray, +2 authors, Powel H Brown.
Breast Cancer Res Treat, 2012 Jan 04; 134(1). PMID: 22212555    Free PMC article.
'Omic approaches to preventing or managing metastatic breast cancer.
Obi L Griffith, Joe W Gray.
Breast Cancer Res, 2012 Jan 06; 13(6). PMID: 22216753    Free PMC article.
Review.
Characterization and clinical evaluation of CD10+ stroma cells in the breast cancer microenvironment.
Christine Desmedt, Samira Majjaj, +18 authors, Christos Sotiriou.
Clin Cancer Res, 2012 Jan 12; 18(4). PMID: 22235100    Free PMC article.
Association of HADHA expression with the risk of breast cancer: targeted subset analysis and meta-analysis of microarray data.
Manju Mamtani, Hemant Kulkarni.
BMC Res Notes, 2012 Jan 14; 5. PMID: 22240105    Free PMC article.
Integrated proteomic, transcriptomic, and biological network analysis of breast carcinoma reveals molecular features of tumorigenesis and clinical relapse.
Marcin Imielinski, Sangwon Cha, +3 authors, Dennis C Sgroi.
Mol Cell Proteomics, 2012 Jan 14; 11(6). PMID: 22240506    Free PMC article.
Core module biomarker identification with network exploration for breast cancer metastasis.
Ruoting Yang, Bernie J Daigle, Linda R Petzold, Francis J Doyle.
BMC Bioinformatics, 2012 Jan 20; 13. PMID: 22257533    Free PMC article.
A three-gene model to robustly identify breast cancer molecular subtypes.
Benjamin Haibe-Kains, Christine Desmedt, +4 authors, Christos Sotiriou.
J Natl Cancer Inst, 2012 Jan 21; 104(4). PMID: 22262870    Free PMC article.
Highly Cited.
ErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancers.
Paola D Vermeer, Megan Bell, +9 authors, John H Lee.
PLoS One, 2012 Jan 27; 7(1). PMID: 22279592    Free PMC article.
The PKCθ pathway participates in the aberrant accumulation of Fra-1 protein in invasive ER-negative breast cancer cells.
K Belguise, S Milord, +3 authors, D Chalbos.
Oncogene, 2012 Jan 31; 31(47). PMID: 22286759    Free PMC article.
"I don't think we're in Kansas anymore, Toto".
Joseph O'Donnell.
J Cancer Educ, 2012 Feb 02; 27(1). PMID: 22293911
Integrated cross-species transcriptional network analysis of metastatic susceptibility.
Ying Hu, Gang Wu, +4 authors, Kent W Hunter.
Proc Natl Acad Sci U S A, 2012 Feb 07; 109(8). PMID: 22308418    Free PMC article.
NEFL mRNA expression level is a prognostic factor for early-stage breast cancer patients.
Xiao-Qing Li, Lin Li, Chun-Hua Xiao, Yu-Mei Feng.
PLoS One, 2012 Feb 10; 7(2). PMID: 22319610    Free PMC article.
A novel significance score for gene selection and ranking.
Yufei Xiao, Tzu-Hung Hsiao, +4 authors, Yidong Chen.
Bioinformatics, 2012 Feb 11; 30(6). PMID: 22321699    Free PMC article.
Shortening of 3'UTRs correlates with poor prognosis in breast and lung cancer.
Antonio Lembo, Ferdinando Di Cunto, Paolo Provero.
PLoS One, 2012 Feb 22; 7(2). PMID: 22347440    Free PMC article.
RORα suppresses breast tumor invasion by inducing SEMA3F expression.
Gaofeng Xiong, Chi Wang, +2 authors, Ren Xu.
Cancer Res, 2012 Feb 22; 72(7). PMID: 22350413    Free PMC article.
A gene signature for predicting outcome in patients with basal-like breast cancer.
Robin M Hallett, Anna Dvorkin-Gheva, Anita Bane, John A Hassell.
Sci Rep, 2012 Feb 23; 2. PMID: 22355741    Free PMC article.
Transcriptomic landscape of breast cancers through mRNA sequencing.
Jeyanthy Eswaran, Dinesh Cyanam, +7 authors, Rakesh Kumar.
Sci Rep, 2012 Feb 23; 2. PMID: 22355776    Free PMC article.
Attenuation of TGF-β signaling suppresses premature senescence in a p21-dependent manner and promotes oncogenic Ras-mediated metastatic transformation in human mammary epithelial cells.
Shu Lin, Junhua Yang, +7 authors, Lu-Zhe Sun.
Mol Biol Cell, 2012 Feb 24; 23(8). PMID: 22357622    Free PMC article.
Proteomics of mouse BRCA1-deficient mammary tumors identifies DNA repair proteins with potential diagnostic and prognostic value in human breast cancer.
Marc Warmoes, Janneke E Jaspers, +8 authors, Connie R Jimenez.
Mol Cell Proteomics, 2012 Mar 01; 11(7). PMID: 22366898    Free PMC article.
Application of microarray in breast cancer: An overview.
Rajnish Kumar, Anju Sharma, Rajesh Kumar Tiwari.
J Pharm Bioallied Sci, 2012 Mar 01; 4(1). PMID: 22368395    Free PMC article.
Maximizing biomarker discovery by minimizing gene signatures.
Chang Chang, Junwei Wang, +7 authors, Tieliu Shi.
BMC Genomics, 2012 Mar 06; 12 Suppl 5. PMID: 22369133    Free PMC article.
A prognostic gene expression profile that predicts circulating tumor cell presence in breast cancer patients.
Timothy J Molloy, Paul Roepman, Bjørn Naume, Laura J van't Veer.
PLoS One, 2012 Mar 03; 7(2). PMID: 22384245    Free PMC article.
Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop.
Nicola Aceto, Nina Sausgruber, +12 authors, Mohamed Bentires-Alj.
Nat Med, 2012 Mar 06; 18(4). PMID: 22388088
Highly Cited.
Phosphorylation by p38 mitogen-activated protein kinase promotes estrogen receptor α turnover and functional activity via the SCF(Skp2) proteasomal complex.
Shweta Bhatt, Zhen Xiao, Zhaojing Meng, Benita S Katzenellenbogen.
Mol Cell Biol, 2012 Mar 21; 32(10). PMID: 22431515    Free PMC article.
Gene Selection using a High-Dimensional Regression Model with Microarrays in Cancer Prognostic Studies.
Shuhei Kaneko, Akihiro Hirakawa, Chikuma Hamada.
Cancer Inform, 2012 Mar 24; 11. PMID: 22442625    Free PMC article.
Comparison of the RNA-based EndoPredict multigene test between core biopsies and corresponding surgical breast cancer sections.
Berit Maria Müller, Jan C Brase, +7 authors, Carsten Denkert.
J Clin Pathol, 2012 Mar 27; 65(7). PMID: 22447922    Free PMC article.
Sample-level enrichment analysis unravels shared stress phenotypes among multiple cancer types.
Gunes Gundem, Nuria Lopez-Bigas.
Genome Med, 2012 Mar 31; 4(3). PMID: 22458606    Free PMC article.
Targeting the insulin-like growth factor receptor: developing biomarkers from gene expression profiling.
David N Boone, Adrian V Lee.
Crit Rev Oncog, 2012 Apr 05; 17(2). PMID: 22471706    Free PMC article.
Review.
Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer.
Qing Cheng, Jeffrey T Chang, +4 authors, H Kim Lyerly.
Breast Cancer Res, 2012 Apr 19; 14(2). PMID: 22510516    Free PMC article.
Microenvironments dictating tumor cell dormancy.
Paloma Bragado, Maria Soledad Sosa, +2 authors, Julio A Aguirre-Ghiso.
Recent Results Cancer Res, 2012 Apr 25; 195. PMID: 22527492    Free PMC article.
Review.
Dormancy signatures and metastasis in estrogen receptor positive and negative breast cancer.
Ryung S Kim, Alvaro Avivar-Valderas, +4 authors, Jeffrey E Segall.
PLoS One, 2012 Apr 25; 7(4). PMID: 22530051    Free PMC article.
Induction of the RNA regulator LIN28A is required for the growth and pathogenesis of RESTless breast tumors.
Kearney T W Gunsalus, Matthew P Wagoner, +6 authors, Avtar Roopra.
Cancer Res, 2012 Apr 26; 72(13). PMID: 22532168    Free PMC article.
Concordance among gene expression-based predictors for ER-positive breast cancer treated with adjuvant tamoxifen.
A Prat, J S Parker, +9 authors, C M Perou.
Ann Oncol, 2012 Apr 26; 23(11). PMID: 22532584    Free PMC article.
Improving biomarker list stability by integration of biological knowledge in the learning process.
Tiziana Sanavia, Fabio Aiolli, +2 authors, Barbara Di Camillo.
BMC Bioinformatics, 2012 May 02; 13 Suppl 4. PMID: 22536969    Free PMC article.
Age of 40 years or younger is an independent risk factor for locoregional failure in early breast cancer: a single-institutional analysis in saudi arabia.
Volker Rudat, Hamdan El-Sweilmeen, +5 authors, Saleh Altuwaijri.
J Oncol, 2012 May 01; 2012. PMID: 22545048    Free PMC article.
RNA processing and modification protein, carbon catabolite repression 4 (Ccr4), arrests the cell cycle through p21-dependent and p53-independent pathway.
Xia Yi, Mei Hong, +6 authors, Yongfeng Shang.
J Biol Chem, 2012 May 02; 287(25). PMID: 22547059    Free PMC article.
Prognostic gene signatures for patient stratification in breast cancer: accuracy, stability and interpretability of gene selection approaches using prior knowledge on protein-protein interactions.
Yupeng Cun, Holger Fröhlichholger Fröhlich.
BMC Bioinformatics, 2012 May 03; 13. PMID: 22548963    Free PMC article.
Next generation sequencing and a new era of medicine.
Graham Casey, David Conti, Robert Haile, David Duggan.
Gut, 2012 May 03; 62(6). PMID: 22550129    Free PMC article.
Review.
A critical evaluation of network and pathway-based classifiers for outcome prediction in breast cancer.
Christine Staiger, Sidney Cadot, +4 authors, Lodewyk F A Wessels.
PLoS One, 2012 May 05; 7(4). PMID: 22558100    Free PMC article.
Centromere protein-A, an essential centromere protein, is a prognostic marker for relapse in estrogen receptor-positive breast cancer.
Susan L McGovern, Yuan Qi, +2 authors, Thomas A Buchholz.
Breast Cancer Res, 2012 May 09; 14(3). PMID: 22559056    Free PMC article.
Crk adaptor proteins act as key signaling integrators for breast tumorigenesis.
Kelly E Fathers, Emily S Bell, +12 authors, Morag Park.
Breast Cancer Res, 2012 May 10; 14(3). PMID: 22569336    Free PMC article.
Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila.
S K Pallavi, Diana M Ho, +2 authors, Spyros Artavanis-Tsakonas.
EMBO J, 2012 May 15; 31(13). PMID: 22580825    Free PMC article.
Adoption of gene expression profile testing and association with use of chemotherapy among women with breast cancer.
Michael J Hassett, Samuel M Silver, +12 authors, Jane C Weeks.
J Clin Oncol, 2012 May 16; 30(18). PMID: 22585699    Free PMC article.
Comparison of data-merging methods with SVM attribute selection and classification in breast cancer gene expression.
Vitoantonio Bevilacqua, Paolo Pannarale, +3 authors, Stefania Tommasi.
BMC Bioinformatics, 2012 May 25; 13 Suppl 7. PMID: 22595006    Free PMC article.
Preclinical and clinical studies of estrogen deprivation support the PDGF/Abl pathway as a novel therapeutic target for overcoming endocrine resistance in breast cancer.
Marion T Weigel, Zara Ghazoui, +3 authors, Lesley-Ann Martin.
Breast Cancer Res, 2012 May 23; 14(3). PMID: 22608253    Free PMC article.
The practical effect of batch on genomic prediction.
Hilary S Parker, Jeffrey T Leek.
Stat Appl Genet Mol Biol, 2012 May 23; 11(3). PMID: 22611599    Free PMC article.
Google goes cancer: improving outcome prediction for cancer patients by network-based ranking of marker genes.
Christof Winter, Glen Kristiansen, +18 authors, Robert Grützmann.
PLoS Comput Biol, 2012 May 23; 8(5). PMID: 22615549    Free PMC article.
Evaluation of activity and combination strategies with the microtubule-targeting drug sagopilone in breast cancer cell lines.
Julia Eschenbrenner, Sebastian Winsel, +11 authors, Jens Hoffmann.
Front Oncol, 2011 Jan 01; 1. PMID: 22649765    Free PMC article.
Strategies for the discovery and development of therapies for metastatic breast cancer.
Bedrich L Eckhardt, Prudence A Francis, Belinda S Parker, Robin L Anderson.
Nat Rev Drug Discov, 2012 Jun 02; 11(6). PMID: 22653217
Highly Cited. Review.
Nucleic acid-based diagnostics for infectious diseases in public health affairs.
Albert Cheung-Hoi Yu, Greg Vatcher, +9 authors, Lok-Ting Lau.
Front Med, 2012 Jun 05; 6(2). PMID: 22660977    Free PMC article.
Review.
Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance.
Justin M Balko, Rebecca S Cook, +15 authors, Carlos L Arteaga.
Nat Med, 2012 Jun 12; 18(7). PMID: 22683778    Free PMC article.
Highly Cited.
Global secretome analysis identifies novel mediators of bone metastasis.
Mario Andres Blanco, Gary LeRoy, +4 authors, Yibin Kang.
Cell Res, 2012 Jun 13; 22(9). PMID: 22688892    Free PMC article.
Cancer core modules identification through genomic and transcriptomic changes correlation detection at network level.
Wenting Li, Rui Wang, +2 authors, Zhirong Sun.
BMC Syst Biol, 2012 Jun 14; 6. PMID: 22691569    Free PMC article.
Network-induced classification kernels for gene expression profile analysis.
Ofer Lavi, Gideon Dror, Ron Shamir.
J Comput Biol, 2012 Jun 16; 19(6). PMID: 22697242    Free PMC article.
TOP2A RNA expression and recurrence in estrogen receptor-positive breast cancer.
Joseph A Sparano, Lori J Goldstein, +2 authors, Robert Gray.
Breast Cancer Res Treat, 2012 Jun 19; 134(2). PMID: 22706628    Free PMC article.
Stromal genes add prognostic information to proliferation and histoclinical markers: a basis for the next generation of breast cancer gene signatures.
Dwain Mefford, Joel Mefford.
PLoS One, 2012 Jun 22; 7(6). PMID: 22719844    Free PMC article.
Independent and functional validation of a multi-tumour-type proliferation signature.
M H W Starmans, N G Lieuwes, +8 authors, P Lambin.
Br J Cancer, 2012 Jun 23; 107(3). PMID: 22722312    Free PMC article.
Distinct regulation of cytoplasmic calcium signals and cell death pathways by different plasma membrane calcium ATPase isoforms in MDA-MB-231 breast cancer cells.
Merril C Curry, Nicole A Luk, +2 authors, Gregory R Monteith.
J Biol Chem, 2012 Jun 27; 287(34). PMID: 22733819    Free PMC article.
Likelihood-based selection and sharp parameter estimation.
Xiaotong Shen, Wei Pan, Yunzhang Zhu.
J Am Stat Assoc, 2012 Jun 28; 107(497). PMID: 22736876    Free PMC article.
High-throughput molecular analysis from leftover of fine needle aspiration cytology of mammographically detected breast cancer.
Laura Annaratone, Caterina Marchiò, +13 authors, Anna Sapino.
Transl Oncol, 2012 Jun 29; 5(3). PMID: 22741037    Free PMC article.
PAM50 assay and the three-gene model for identifying the major and clinically relevant molecular subtypes of breast cancer.
A Prat, J S Parker, C Fan, C M Perou.
Breast Cancer Res Treat, 2012 Jul 04; 135(1). PMID: 22752290    Free PMC article.
Pathway-based classification of cancer subtypes.
Shinuk Kim, Mark Kon, Charles DeLisi.
Biol Direct, 2012 Jul 05; 7. PMID: 22759382    Free PMC article.
Identifying transcription factors and microRNAs as key regulators of pathways using Bayesian inference on known pathway structures.
Damian Roqueiro, Lei Huang, Yang Dai.
Proteome Sci, 2012 Jul 05; 10 Suppl 1. PMID: 22759573    Free PMC article.
Unmasking epithelial-mesenchymal transition in a breast cancer primary culture: a study report.
Luigi Minafra, Rossana Norata, +4 authors, Cristina Messa.
BMC Res Notes, 2012 Jul 05; 5. PMID: 22759679    Free PMC article.
I-spline Smoothing for Calibrating Predictive Models.
Yuan Wu, Xiaoqian Jiang, Jihoon Kim, Lucila Ohno-Machado.
AMIA Jt Summits Transl Sci Proc, 2012 Jul 11; 2012. PMID: 22779048    Free PMC article.
Exploring molecular links between lymph node invasion and cancer prognosis in human breast cancer.
Sangwoo Kim, Hojung Nam, Doheon Lee.
BMC Syst Biol, 2012 Jul 20; 5 Suppl 2. PMID: 22784575    Free PMC article.
Integration of breast cancer gene signatures based on graph centrality.
Jianxin Wang, Gang Chen, Min Li, Yi Pan.
BMC Syst Biol, 2012 Jul 20; 5 Suppl 3. PMID: 22784616    Free PMC article.
Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers.
I-Ming Wang, Bin Zhang, +24 authors, Christopher Roberts.
Mol Syst Biol, 2012 Jul 19; 8. PMID: 22806142    Free PMC article.
Integration of clinical and gene expression data has a synergetic effect on predicting breast cancer outcome.
Martin H van Vliet, Hugo M Horlings, +2 authors, Lodewyk F A Wessels.
PLoS One, 2012 Jul 19; 7(7). PMID: 22808140    Free PMC article.
Distinct genes related to drug response identified in ER positive and ER negative breast cancer cell lines.
Kui Shen, Shara D Rice, +9 authors, Nan Song.
PLoS One, 2012 Jul 21; 7(7). PMID: 22815861    Free PMC article.
Identification of a selective small-molecule inhibitor series targeting the eyes absent 2 (Eya2) phosphatase activity.
Aaron B Krueger, Seameen J Dehdashti, +6 authors, Rui Zhao.
J Biomol Screen, 2012 Jul 24; 18(1). PMID: 22820394    Free PMC article.
Validation of a radiosensitivity molecular signature in breast cancer.
Steven A Eschrich, William J Fulp, +9 authors, Javier F Torres-Roca.
Clin Cancer Res, 2012 Jul 27; 18(18). PMID: 22832933    Free PMC article.
Adhesion receptors as therapeutic targets for circulating tumor cells.
Jiahe Li, Michael R King.
Front Oncol, 2012 Jul 28; 2. PMID: 22837985    Free PMC article.
Integrating gene expression and protein-protein interaction network to prioritize cancer-associated genes.
Chao Wu, Jun Zhu, Xuegong Zhang.
BMC Bioinformatics, 2012 Jul 31; 13. PMID: 22838965    Free PMC article.
The prognostic importance of cathepsin D and E-cadherin in early breast cancer: A single-institution experience.
Galia Jacobson-Raber, Irena Lazarev, +5 authors, Samuel Ariad.
Oncol Lett, 2012 Aug 01; 2(6). PMID: 22848286    Free PMC article.
HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers.
Marc L Mendillo, Sandro Santagata, +7 authors, Susan Lindquist.
Cell, 2012 Aug 07; 150(3). PMID: 22863008    Free PMC article.
Highly Cited.
An "elite hacker": breast tumors exploit the normal microenvironment program to instruct their progression and biological diversity.
Aaron Boudreau, Laura J van't Veer, Mina J Bissell.
Cell Adh Migr, 2012 Aug 07; 6(3). PMID: 22863741    Free PMC article.
Review.
Transcriptional network analysis identifies BACH1 as a master regulator of breast cancer bone metastasis.
Yajun Liang, Heng Wu, +8 authors, Yibin Kang.
J Biol Chem, 2012 Aug 10; 287(40). PMID: 22875853    Free PMC article.
Mouse p53-deficient cancer models as platforms for obtaining genomic predictors of human cancer clinical outcomes.
Marta Dueñas, Mirentxu Santos, +13 authors, Ramón García-Escudero.
PLoS One, 2012 Aug 11; 7(8). PMID: 22880004    Free PMC article.
The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites.
Hua Gao, Goutam Chakraborty, +7 authors, Filippo G Giancotti.
Cell, 2012 Aug 21; 150(4). PMID: 22901808    Free PMC article.
Highly Cited.
GOLPH3 overexpression correlates with tumor progression and poor prognosis in patients with clinically N0 oral tongue cancer.
Huan Li, Ling Guo, +5 authors, Ming Song.
J Transl Med, 2012 Aug 22; 10. PMID: 22905766    Free PMC article.
An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer.
Hui Li, Sara Duhachek-Muggy, +3 authors, Anna Zolkiewska.
Breast Cancer Res Treat, 2012 Aug 29; 135(3). PMID: 22926263    Free PMC article.
TMEM45A is essential for hypoxia-induced chemoresistance in breast and liver cancer cells.
Lionel Flamant, Edith Roegiers, +6 authors, Carine Michiels.
BMC Cancer, 2012 Sep 08; 12. PMID: 22954140    Free PMC article.
The molecular profile of luminal B breast cancer.
Chad J Creighton.
Biologics, 2012 Sep 08; 6. PMID: 22956860    Free PMC article.
High TWIST1 mRNA expression is associated with poor prognosis in lymph node-negative and estrogen receptor-positive human breast cancer and is co-expressed with stromal as well as ECM related genes.
Muhammad Riaz, Anieta M Sieuwerts, +4 authors, John W M Martens.
Breast Cancer Res, 2012 Sep 13; 14(5). PMID: 22967435    Free PMC article.
Cancer cell growth and survival as a system-level property sustained by enhanced glycolysis and mitochondrial metabolic remodeling.
Lilia Alberghina, Daniela Gaglio, +7 authors, Marco Vanoni.
Front Physiol, 2012 Sep 19; 3. PMID: 22988443    Free PMC article.
Cellular mechanisms of zinc dysregulation: a perspective on zinc homeostasis as an etiological factor in the development and progression of breast cancer.
Samina Alam, Shannon L Kelleher.
Nutrients, 2012 Sep 28; 4(8). PMID: 23016122    Free PMC article.
Review.
Identification of common prognostic gene expression signatures with biological meanings from microarray gene expression datasets.
Jun Yao, Qi Zhao, +4 authors, John N Weinstein.
PLoS One, 2012 Oct 03; 7(9). PMID: 23029298    Free PMC article.
EndoPredict improves the prognostic classification derived from common clinical guidelines in ER-positive, HER2-negative early breast cancer.
P Dubsky, M Filipits, +17 authors, Austrian Breast and Colorectal Cancer Study Group (ABCSG).
Ann Oncol, 2012 Oct 05; 24(3). PMID: 23035151    Free PMC article.
VAMP-associated protein B (VAPB) promotes breast tumor growth by modulation of Akt activity.
Meghana Rao, Wenqiang Song, +5 authors, Jin Chen.
PLoS One, 2012 Oct 11; 7(10). PMID: 23049696    Free PMC article.
Molecular characteristics and metastasis predictor genes of triple-negative breast cancer: a clinical study of triple-negative breast carcinomas.
Wen-Hung Kuo, Yao-Yin Chang, +4 authors, Eric Y Chuang.
PLoS One, 2012 Oct 11; 7(9). PMID: 23049873    Free PMC article.
Network analysis of gene lists for finding reproducible prognostic breast cancer gene signatures.
Ulykbek Kairov, Tatyana Karpenyuk, Erlan Ramanculov, Andrei Zinovyev.
Bioinformation, 2012 Oct 12; 8(16). PMID: 23055628    Free PMC article.
Neutrophil gelatinase-associated lipocalin (NGAL) predicts response to neoadjuvant chemotherapy and clinical outcome in primary human breast cancer.
Antonia Sophie Wenners, Keyur Mehta, +16 authors, Maret Bauer.
PLoS One, 2012 Oct 12; 7(10). PMID: 23056218    Free PMC article.
GREB1 functions as a growth promoter and is modulated by IL6/STAT3 in breast cancer.
Mingli Liu, Guangdi Wang, Carmen R Gomez-Fernandez, Shanchun Guo.
PLoS One, 2012 Oct 12; 7(10). PMID: 23056300    Free PMC article.
Estrogen receptor prevents p53-dependent apoptosis in breast cancer.
Shannon T Bailey, Hyunjin Shin, +2 authors, Myles Brown.
Proc Natl Acad Sci U S A, 2012 Oct 19; 109(44). PMID: 23077249    Free PMC article.
Circulating tumor cells, disease recurrence and survival in newly diagnosed breast cancer.
Bas Franken, Marco R de Groot, +4 authors, Leon W M M Terstappen.
Breast Cancer Res, 2012 Oct 24; 14(5). PMID: 23088337    Free PMC article.
A molecular assay of tumor radiosensitivity: a roadmap towards biology-based personalized radiation therapy.
Javier F Torres-Roca.
Per Med, 2012 Oct 30; 9(5). PMID: 23105945    Free PMC article.
Evaluating the prognostic significance of FBXW7 expression level in human breast cancer by a meta-analysis of transcriptional profiles.
Guangwei Wei, Yunshan Wang, +2 authors, Jian-Hua Mao.
J Cancer Sci Ther, 2012 Oct 30; 4(9). PMID: 23105958    Free PMC article.
Selective gene-expression profiling of migratory tumor cells in vivo predicts clinical outcome in breast cancer patients.
Antonia Patsialou, Yarong Wang, +4 authors, John S Condeelis.
Breast Cancer Res, 2012 Nov 02; 14(5). PMID: 23113900    Free PMC article.
A Steiner tree-based method for biomarker discovery and classification in breast cancer metastasis.
Md Jamiul Jahid, Jianhua Ruan.
BMC Genomics, 2012 Nov 21; 13 Suppl 6. PMID: 23134806    Free PMC article.
Doubly Optimized Calibrated Support Vector Machine (DOC-SVM): an algorithm for joint optimization of discrimination and calibration.
Xiaoqian Jiang, Aditya Menon, +2 authors, Lucila Ohno-Machado.
PLoS One, 2012 Nov 10; 7(11). PMID: 23139819    Free PMC article.
Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis.
Nora Pencheva, Hien Tran, +4 authors, Sohail F Tavazoie.
Cell, 2012 Nov 13; 151(5). PMID: 23142051    Free PMC article.
Highly Cited.
Identifying protein interaction subnetworks by a bagging Markov random field-based method.
Li Chen, Jianhua Xuan, +2 authors, Robert Clarke.
Nucleic Acids Res, 2012 Nov 20; 41(2). PMID: 23161673    Free PMC article.
Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors.
Marcus Schmidt, Patrick Micke, Mathias Gehrmann, Jan G Hengstler.
Oncoimmunology, 2012 Nov 22; 1(7). PMID: 23170262    Free PMC article.
Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ.
S Jin, A P Mutvei, +13 authors, U Lendahl.
Oncogene, 2012 Nov 28; 32(41). PMID: 23178494    Free PMC article.
Expression of aurora kinase A is associated with metastasis-free survival in node-negative breast cancer patients.
Wulf Siggelkow, Daniel Boehm, +12 authors, Marcus Schmidt.
BMC Cancer, 2012 Nov 29; 12. PMID: 23186136    Free PMC article.
An array CGH based genomic instability index (G2I) is predictive of clinical outcome in breast cancer and reveals a subset of tumors without lymph node involvement but with poor prognosis.
Françoise Bonnet, Mickael Guedj, +14 authors, Michel Longy.
BMC Med Genomics, 2012 Nov 29; 5. PMID: 23186559    Free PMC article.
Non-invasive proteomics-thinking about personalized breast cancer screening and treatment.
Manuel Debald, Matthias Wolfgarten, +2 authors, Michael Braun.
EPMA J, 2010 Sep 01; 1(3). PMID: 23199085    Free PMC article.
Prediction and prognosis: impact of gene expression profiling in personalized treatment of breast cancer patients.
Michael R Mallmann, Andrea Staratschek-Jox, +5 authors, Joachim L Schultze.
EPMA J, 2010 Sep 01; 1(3). PMID: 23199086    Free PMC article.
Peptide-based selective inhibitors of matrix metalloproteinase-mediated activities.
Margaret W Ndinguri, Manishabrata Bhowmick, +2 authors, Gregg B Fields.
Molecules, 2012 Dec 04; 17(12). PMID: 23201642    Free PMC article.
Identifying grade/stage-related active modules in human co-regulatory networks: a case study for breast cancer.
Chenchen Feng, Lina Chen, +7 authors, Weiming He.
OMICS, 2012 Dec 12; 16(12). PMID: 23215806    Free PMC article.
Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer.
Chi-Rong Li, Jimmy J-M Su, +10 authors, Kelvin K-C Tsai.
Am J Pathol, 2012 Dec 12; 182(2). PMID: 23219426    Free PMC article.
Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancer.
Erin D Giles, Elizabeth A Wellberg, +6 authors, Paul S Maclean.
Cancer Res, 2012 Dec 12; 72(24). PMID: 23222299    Free PMC article.
Molecular profiles of pre- and postoperative breast cancer tumours reveal differentially expressed genes.
Margit L H Riis, Torben Lüders, +4 authors, Ida R K Bukholm.
ISRN Oncol, 2012 Dec 12; 2012. PMID: 23227362    Free PMC article.
Clinical and multiple gene expression variables in survival analysis of breast cancer: analysis with the hypertabastic survival model.
Mohammad A Tabatabai, Wayne M Eby, +2 authors, Karan P Singh.
BMC Med Genomics, 2012 Dec 18; 5. PMID: 23241496    Free PMC article.
Gene expression profiles for predicting metastasis in breast cancer: a cross-study comparison of classification methods.
Mark Burton, Mads Thomassen, Qihua Tan, Torben A Kruse.
ScientificWorldJournal, 2012 Dec 20; 2012. PMID: 23251101    Free PMC article.
Prognostically relevant gene signatures of high-grade serous ovarian carcinoma.
Roel G W Verhaak, Pablo Tamayo, +39 authors, Cancer Genome Atlas Research Network.
J Clin Invest, 2012 Dec 22; 123(1). PMID: 23257362    Free PMC article.
Highly Cited.
14-3-3ζ as a predictor of early time to recurrence and distant metastasis in hormone receptor-positive and -negative breast cancers.
Anna Bergamaschi, Jonna Frasor, +5 authors, Benita S Katzenellenbogen.
Breast Cancer Res Treat, 2012 Dec 29; 137(3). PMID: 23271328    Free PMC article.
Statistical aspects of omics data analysis using the random compound covariate.
Pei-Fang Su, Xi Chen, Heidi Chen, Yu Shyr.
BMC Syst Biol, 2013 Jan 11; 6 Suppl 3. PMID: 23281681    Free PMC article.
Pathway correlation profile of gene-gene co-expression for identifying pathway perturbation.
Allison N Tegge, Charles W Caldwell, Dong Xu.
PLoS One, 2013 Jan 04; 7(12). PMID: 23284898    Free PMC article.
RamiGO: an R/Bioconductor package providing an AmiGO visualize interface.
Markus S Schröder, Daniel Gusenleitner, +2 authors, Benjamin Haibe-Kains.
Bioinformatics, 2013 Jan 09; 29(5). PMID: 23297033    Free PMC article.
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.
Maria Kalyuga, David Gallego-Ortega, +27 authors, Christopher J Ormandy.
PLoS Biol, 2013 Jan 10; 10(12). PMID: 23300383    Free PMC article.
Prediction of breast cancer metastasis by gene expression profiles: a comparison of metagenes and single genes.
Mark Burton, Mads Thomassen, Qihua Tan, Torben A Kruse.
Cancer Inform, 2013 Jan 11; 11. PMID: 23304070    Free PMC article.
Towards mechanism classifiers: expression-anchored Gene Ontology signature predicts clinical outcome in lung adenocarcinoma patients.
Xinan Yang, Haiquan Li, +3 authors, Yves A Lussier.
AMIA Annu Symp Proc, 2013 Jan 11; 2012. PMID: 23304380    Free PMC article.
Elafin, an inhibitor of elastase, is a prognostic indicator in breast cancer.
Kelly K Hunt, Hannah Wingate, +8 authors, Khandan Keyomarsi.
Breast Cancer Res, 2013 Jan 17; 15(1). PMID: 23320734    Free PMC article.
Differences in degradation lead to asynchronous expression of cyclin E1 and cyclin E2 in cancer cells.
C Elizabeth Caldon, C Marcelo Sergio, Robert L Sutherland, Elizabeth A Musgrove.
Cell Cycle, 2013 Jan 18; 12(4). PMID: 23324394    Free PMC article.
Cyclin E2 induces genomic instability by mechanisms distinct from cyclin E1.
C Elizabeth Caldon, C Marcelo Sergio, +3 authors, Elizabeth A Musgrove.
Cell Cycle, 2013 Jan 18; 12(4). PMID: 23324395    Free PMC article.
KLF6-SV1 drives breast cancer metastasis and is associated with poor survival.
Raheleh Hatami, Anieta M Sieuwerts, +13 authors, Goutham Narla.
Sci Transl Med, 2013 Jan 25; 5(169). PMID: 23345610    Free PMC article.
Identification and functional annotation of genome-wide ER-regulated genes in breast cancer based on ChIP-Seq data.
Min Ding, Haiyun Wang, +2 authors, Zhonghua Xu.
Comput Math Methods Med, 2013 Jan 25; 2012. PMID: 23346221    Free PMC article.
Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells.
Deborah A Sanders, Caryn S Ross-Innes, +2 authors, Shankar Balasubramanian.
Genome Biol, 2013 Jan 26; 14(1). PMID: 23347430    Free PMC article.
Highly Cited.
Discovery and analysis of consistent active sub-networks in cancers.
Raj K Gaire, Lorey Smith, +3 authors, Izhak Haviv.
BMC Bioinformatics, 2013 Feb 13; 14 Suppl 2. PMID: 23368093    Free PMC article.
Breast cancer subtyping from plasma proteins.
Fan Zhang, Jake Y Chen.
BMC Med Genomics, 2013 Feb 13; 6 Suppl 1. PMID: 23369492    Free PMC article.
Outcome of metastatic breast cancer in selected women with or without deleterious BRCA mutations.
S Bayraktar, A M Gutierrez-Barrera, +10 authors, B K Arun.
Clin Exp Metastasis, 2013 Feb 02; 30(5). PMID: 23370825    Free PMC article.
Ink4a/Arf(-/-) and HRAS(G12V) transform mouse mammary cells into triple-negative breast cancer containing tumorigenic CD49f(-) quiescent cells.
K Kai, T Iwamoto, +10 authors, N T Ueno.
Oncogene, 2013 Feb 05; 33(4). PMID: 23376849    Free PMC article.
Translating metastasis-related biomarkers to the clinic--progress and pitfalls.
François-Clément Bidard, Jean-Yves Pierga, Jean-Charles Soria, Jean Paul Thiery.
Nat Rev Clin Oncol, 2013 Feb 06; 10(3). PMID: 23381003
Review.
Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data.
Miriam Ragle Aure, Israel Steinfeld, +9 authors, Zohar Yakhini.
PLoS One, 2013 Feb 06; 8(1). PMID: 23382830    Free PMC article.
A data similarity-based strategy for meta-analysis of transcriptional profiles in cancer.
Qingchao Qiu, Pengcheng Lu, +6 authors, Yajun Yi.
PLoS One, 2013 Feb 06; 8(1). PMID: 23383020    Free PMC article.
Extracting insights from the shape of complex data using topology.
P Y Lum, G Singh, +5 authors, G Carlsson.
Sci Rep, 2013 Feb 09; 3. PMID: 23393618    Free PMC article.
Highly Cited.
Molecular signature of cancer at gene level or pathway level? Case studies of colorectal cancer and prostate cancer microarray data.
Jiajia Chen, Ying Wang, Bairong Shen, Daqing Zhang.
Comput Math Methods Med, 2013 Feb 13; 2013. PMID: 23401724    Free PMC article.
Molecular characterization of basal-like and non-basal-like triple-negative breast cancer.
Aleix Prat, Barbara Adamo, +3 authors, Charles M Perou.
Oncologist, 2013 Feb 14; 18(2). PMID: 23404817    Free PMC article.
Highly Cited. Review.
PAM50 proliferation score as a predictor of weekly paclitaxel benefit in breast cancer.
Miguel Martín, Aleix Prat, +24 authors, Philip S Bernard.
Breast Cancer Res Treat, 2013 Feb 21; 138(2). PMID: 23423445    Free PMC article.
Improved shrunken centroid classifiers for high-dimensional class-imbalanced data.
Rok Blagus, Lara Lusa.
BMC Bioinformatics, 2013 Feb 26; 14. PMID: 23433084    Free PMC article.
Bridging cancer biology with the clinic: relative expression of a GRHL2-mediated gene-set pair predicts breast cancer metastasis.
Xinan Yang, Prabhakaran Vasudevan, +2 authors, John M Cunningham.
PLoS One, 2013 Feb 27; 8(2). PMID: 23441166    Free PMC article.
Classification of tumor samples from expression data using decision trunks.
Benjamin Ulfenborg, Karin Klinga-Levan, Björn Olsson.
Cancer Inform, 2013 Mar 08; 12. PMID: 23467331    Free PMC article.
Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis.
Christophe J Desmet, Tristan Gallenne, +17 authors, Daniel S Peeper.
Proc Natl Acad Sci U S A, 2013 Mar 14; 110(13). PMID: 23483055    Free PMC article.
Highly Cited.
Gene expression profiling of breast cancer survivability by pooled cDNA microarray analysis using logistic regression, artificial neural networks and decision trees.
Hsiu-Ling Chou, Chung-Tay Yao, +10 authors, Chi-Ming Chu.
BMC Bioinformatics, 2013 Mar 20; 14. PMID: 23506640    Free PMC article.
Systems biology approaches for discovering biomarkers for traumatic brain injury.
Jacob D Feala, Mohamed Diwan M Abdulhameed, +6 authors, Jaques Reifman.
J Neurotrauma, 2013 Mar 21; 30(13). PMID: 23510232    Free PMC article.
Review.
Biomarkers of residual disease, disseminated tumor cells, and metastases in the MMTV-PyMT breast cancer model.
Christian Franci, Jenny Zhou, +4 authors, Hosein Kouros-Mehr.
PLoS One, 2013 Mar 23; 8(3). PMID: 23520493    Free PMC article.
Identification of Robust Pathway Markers for Cancer through Rank-Based Pathway Activity Inference.
Navadon Khunlertgit, Byung-Jun Yoon.
Adv Bioinformatics, 2013 Mar 28; 2013. PMID: 23533400    Free PMC article.
Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways.
Margit L H Riis, Xi Zhao, +6 authors, Vessela N Kristensen.
ISRN Oncol, 2013 Mar 28; 2013. PMID: 23533813    Free PMC article.
Stem cell-like gene expression in ovarian cancer predicts type II subtype and prognosis.
Matthew Schwede, Dimitrios Spentzos, +5 authors, Aedín C Culhane.
PLoS One, 2013 Mar 29; 8(3). PMID: 23536770    Free PMC article.
Gene expression profiling in breast cancer.
Belisario A Arango, Celine L Rivera, Stefan Glück.
Am J Transl Res, 2013 Apr 11; 5(2). PMID: 23573359    Free PMC article.
Prognostic microRNA/mRNA signature from the integrated analysis of patients with invasive breast cancer.
Stefano Volinia, Carlo M Croce.
Proc Natl Acad Sci U S A, 2013 Apr 17; 110(18). PMID: 23589849    Free PMC article.
Highly Cited.
Genome-wide analysis of three-way interplay among gene expression, cancer cell invasion and anti-cancer compound sensitivity.
Yi-Chiung Hsu, Hsuan-Yu Chen, +5 authors, Ker-Chau Li.
BMC Med, 2013 Apr 18; 11. PMID: 23590835    Free PMC article.
Using Frequent Co-expression Network to Identify Gene Clusters for Breast Cancer Prognosis.
Jie Zhang, Kun Huang, Yang Xiang, Ruoming Jin.
Proc Int Joint Conf Bioinforma Syst Biol Intell Comput, 2009 Aug 03;. PMID: 23615925    Free PMC article.
A transcriptome-proteome integrated network identifies endoplasmic reticulum thiol oxidoreductase (ERp57) as a hub that mediates bone metastasis.
Naiara Santana-Codina, Rafael Carretero, +9 authors, Angels Sierra.
Mol Cell Proteomics, 2013 Apr 30; 12(8). PMID: 23625662    Free PMC article.
Steiner tree methods for optimal sub-network identification: an empirical study.
Afshin Sadeghi, Holger Fröhlich.
BMC Bioinformatics, 2013 May 01; 14. PMID: 23627667    Free PMC article.
Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the proinflammatory cytokines IL-6 and IL-8.
Zachary C Hartman, Graham M Poage, +8 authors, Powel H Brown.
Cancer Res, 2013 May 02; 73(11). PMID: 23633491    Free PMC article.
Highly Cited.
Identification of potential biomarkers from microarray experiments using multiple criteria optimization.
Matilde L Sánchez-Peña, Clara E Isaza, +3 authors, Mauricio Cabrera-Ríos.
Cancer Med, 2013 May 02; 2(2). PMID: 23634293    Free PMC article.
Association between SPARC mRNA expression, prognosis and response to neoadjuvant chemotherapy in early breast cancer: a pooled in-silico analysis.
Hatem A Azim, Sandeep Singhal, +7 authors, Christos Sotiriou.
PLoS One, 2013 May 03; 8(4). PMID: 23638089    Free PMC article.
Deconvoluting complex tissues for expression quantitative trait locus-based analyses.
Ji-Heui Seo, Qiyuan Li, +5 authors, Matthew L Freedman.
Philos Trans R Soc Lond B Biol Sci, 2013 May 08; 368(1620). PMID: 23650637    Free PMC article.
Expression of VEGF and semaphorin genes define subgroups of triple negative breast cancer.
R Joseph Bender, Feilim Mac Gabhann.
PLoS One, 2013 May 15; 8(5). PMID: 23667446    Free PMC article.
Tumour dormancy and clinical implications in breast cancer.
L Gelao, C Criscitiello, +6 authors, G Curigliano.
Ecancermedicalscience, 2013 May 30; 7. PMID: 23717341    Free PMC article.
Control of metastatic progression by microRNA regulatory networks.
Nora Pencheva, Sohail F Tavazoie.
Nat Cell Biol, 2013 Jun 04; 15(6). PMID: 23728460    Free PMC article.
Highly Cited. Review.
Integrative analysis of cancer-related signaling pathways.
Thomas Kessler, Hendrik Hache, Christoph Wierling.
Front Physiol, 2013 Jun 14; 4. PMID: 23760067    Free PMC article.
Detection of cancer before distant metastasis.
Frank A W Coumans, Sabine Siesling, Leon W M M Terstappen.
BMC Cancer, 2013 Jun 15; 13. PMID: 23763955    Free PMC article.
PDEF promotes luminal differentiation and acts as a survival factor for ER-positive breast cancer cells.
Gilles Buchwalter, Michele M Hickey, +10 authors, Joan S Brugge.
Cancer Cell, 2013 Jun 15; 23(6). PMID: 23764000    Free PMC article.
Metalloproteinase-disintegrin ADAM12 is associated with a breast tumor-initiating cell phenotype.
Hui Li, Sara Duhachek-Muggy, Suzanne Dubnicka, Anna Zolkiewska.
Breast Cancer Res Treat, 2013 Jun 19; 139(3). PMID: 23771733    Free PMC article.
Module-based breast cancer classification.
Yuji Zhang, Jianhua Xuan, Robert Clarke, Habtom W Ressom.
Int J Data Min Bioinform, 2013 Jul 04; 7(3). PMID: 23819260    Free PMC article.
Interrogating differences in expression of targeted gene sets to predict breast cancer outcome.
Sarah A Andres, Guy N Brock, James L Wittliff.
BMC Cancer, 2013 Jul 04; 13. PMID: 23819905    Free PMC article.
BreastMark: an integrated approach to mining publicly available transcriptomic datasets relating to breast cancer outcome.
Stephen F Madden, Colin Clarke, +5 authors, William M Gallagher.
Breast Cancer Res, 2013 Jul 04; 15(4). PMID: 23820017    Free PMC article.
Highly Cited.
Network-based penalized regression with application to genomic data.
Sunkyung Kim, Wei Pan, Xiaotong Shen.
Biometrics, 2013 Jul 05; 69(3). PMID: 23822182    Free PMC article.
Large-scale integrative network-based analysis identifies common pathways disrupted by copy number alterations across cancers.
Tae Hyun Hwang, Gowtham Atluri, +6 authors, Jinfeng Liu.
BMC Genomics, 2013 Jul 05; 14. PMID: 23822816    Free PMC article.
Relationships between LDH-A, lactate, and metastases in 4T1 breast tumors.
Asif Rizwan, Inna Serganova, +6 authors, Jason A Koutcher.
Clin Cancer Res, 2013 Jul 09; 19(18). PMID: 23833310    Free PMC article.
Metasignatures identify two major subtypes of breast cancer.
Q Duan, Y Kou, +2 authors, A Ma'ayan.
CPT Pharmacometrics Syst Pharmacol, 2013 Jul 10; 2. PMID: 23836026    Free PMC article.
Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells.
Alessandra Pincini, Giusy Tornillo, +12 authors, Sara Cabodi.
Cell Cycle, 2013 Jul 11; 12(15). PMID: 23839042    Free PMC article.
Wnt pathway activity in breast cancer sub-types and stem-like cells.
Rebecca Lamb, Matthew P Ablett, +3 authors, Robert B Clarke.
PLoS One, 2013 Jul 19; 8(7). PMID: 23861811    Free PMC article.
Determination of minimum training sample size for microarray-based cancer outcome prediction-an empirical assessment.
Li Shao, Xiaohui Fan, +2 authors, Yiyu Cheng.
PLoS One, 2013 Jul 19; 8(7). PMID: 23861920    Free PMC article.
Using large-scale molecular data sets to improve breast cancer treatment.
Chad J Creighton.
Breast Cancer Manag, 2012 May 01; 1(1). PMID: 23869198    Free PMC article.
Glycoprotein non-metastatic b (GPNMB): A metastatic mediator and emerging therapeutic target in cancer.
Gordana Maric, April An Rose, Matthew G Annis, Peter M Siegel.
Onco Targets Ther, 2013 Jul 23; 6. PMID: 23874106    Free PMC article.
REACTIN: regulatory activity inference of transcription factors underlying human diseases with application to breast cancer.
Mingzhu Zhu, Chun-Chi Liu, Chao Cheng.
BMC Genomics, 2013 Jul 28; 14. PMID: 23885756    Free PMC article.
Symbolic data analysis to defy low signal-to-noise ratio in microarray data for breast cancer prognosis.
Lyamine Hedjazi, Marie-Veronique Le Lann, +3 authors, Gilles Favre.
J Comput Biol, 2013 Aug 01; 20(8). PMID: 23899014    Free PMC article.
Profiling the immune stromal interface in breast cancer and its potential for clinical impact.
Sheeba Irshad, Anita Grigoriadis, +2 authors, Andrew Tutt.
Breast Care (Basel), 2013 Aug 02; 7(4). PMID: 23904829    Free PMC article.
ProteoMirExpress: inferring microRNA and protein-centered regulatory networks from high-throughput proteomic and mRNA expression data.
Jing Qin, Mulin Jun Li, +6 authors, Junwen Wang.
Mol Cell Proteomics, 2013 Aug 09; 12(11). PMID: 23924514    Free PMC article.
Prior robust empirical Bayes inference for large-scale data by conditioning on rank with application to microarray data.
J G Liao, Timothy McMurry, Arthur Berg.
Biostatistics, 2013 Aug 13; 15(1). PMID: 23934072    Free PMC article.
Support vector machine-based nomogram predicts postoperative distant metastasis for patients with oesophageal squamous cell carcinoma.
H X Yang, W Feng, +7 authors, J H Fu.
Br J Cancer, 2013 Aug 15; 109(5). PMID: 23942069    Free PMC article.
A genome-wide siRNA screen identifies proteasome addiction as a vulnerability of basal-like triple-negative breast cancer cells.
Fabio Petrocca, Gabriel Altschuler, +7 authors, Judy Lieberman.
Cancer Cell, 2013 Aug 21; 24(2). PMID: 23948298    Free PMC article.
Highly Cited.
Incorporating prior knowledge into Gene Network Study.
Zixing Wang, Wenlong Xu, F Anthony San Lucas, Yin Liu.
Bioinformatics, 2013 Aug 21; 29(20). PMID: 23956306    Free PMC article.
LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling.
Joan Chang, Monica M Nicolau, +4 authors, Janine T Erler.
Breast Cancer Res, 2013 Aug 27; 15(4). PMID: 23971878    Free PMC article.
RKIP and HMGA2 regulate breast tumor survival and metastasis through lysyl oxidase and syndecan-2.
M Sun, S Gomes, +5 authors, M R Rosner.
Oncogene, 2013 Aug 27; 33(27). PMID: 23975428    Free PMC article.
Unraveling the role of KIAA1199, a novel endoplasmic reticulum protein, in cancer cell migration.
Nikki A Evensen, Cem Kuscu, +8 authors, Jian Cao.
J Natl Cancer Inst, 2013 Aug 31; 105(18). PMID: 23990668    Free PMC article.
Is tail vein injection a relevant breast cancer lung metastasis model?
Omar M Rashid, Masayuki Nagahashi, +7 authors, Kazuaki Takabe.
J Thorac Dis, 2013 Aug 31; 5(4). PMID: 23991292    Free PMC article.
TIG1 promotes the development and progression of inflammatory breast cancer through activation of Axl kinase.
Xiaoping Wang, Hitomi Saso, +10 authors, Naoto T Ueno.
Cancer Res, 2013 Sep 10; 73(21). PMID: 24014597    Free PMC article.
Genetic background may contribute to PAM50 gene expression breast cancer subtype assignments.
Ying Hu, Ling Bai, +5 authors, Kent W Hunter.
PLoS One, 2013 Sep 10; 8(8). PMID: 24015230    Free PMC article.
Prediction of late distant recurrence in patients with oestrogen-receptor-positive breast cancer: a prospective comparison of the breast-cancer index (BCI) assay, 21-gene recurrence score, and IHC4 in the TransATAC study population.
Dennis C Sgroi, Ivana Sestak, +9 authors, Mitch Dowsett.
Lancet Oncol, 2013 Sep 17; 14(11). PMID: 24035531    Free PMC article.
Highly Cited.
Bisected, complex N-glycans and galectins in mouse mammary tumor progression and human breast cancer.
Hazuki E Miwa, Wade R Koba, +3 authors, Pamela Stanley.
Glycobiology, 2013 Sep 17; 23(12). PMID: 24037315    Free PMC article.
Expression profiling of ion channel genes predicts clinical outcome in breast cancer.
Jae-Hong Ko, Eun A Ko, +3 authors, Tong Zhou.
Mol Cancer, 2013 Sep 24; 12(1). PMID: 24053408    Free PMC article.
Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers.
Giampaolo Bianchini, Lajos Pusztai, +16 authors, Luca Gianni.
Breast Cancer Res, 2013 Sep 26; 15(5). PMID: 24060333    Free PMC article.
SurvExpress: an online biomarker validation tool and database for cancer gene expression data using survival analysis.
Raul Aguirre-Gamboa, Hugo Gomez-Rueda, +5 authors, Victor Treviño.
PLoS One, 2013 Sep 26; 8(9). PMID: 24066126    Free PMC article.
Highly Cited.
Network-based inference framework for identifying cancer genes from gene expression data.
Bo Yang, Junying Zhang, Yaling Yin, Yuanyuan Zhang.
Biomed Res Int, 2013 Sep 28; 2013. PMID: 24073403    Free PMC article.
Metastasis tumor-associated protein 2 enhances metastatic behavior and is associated with poor outcomes in estrogen receptor-negative breast cancer.
Kyle R Covington, Lauren Brusco, +7 authors, Suzanne A W Fuqua.
Breast Cancer Res Treat, 2013 Oct 01; 141(3). PMID: 24077732    Free PMC article.
Hierarchy of gene expression data is predictive of future breast cancer outcome.
Man Chen, Michael W Deem.
Phys Biol, 2013 Oct 05; 10(5). PMID: 24091897    Free PMC article.
The fragile X protein binds mRNAs involved in cancer progression and modulates metastasis formation.
Rossella Lucá, Michele Averna, +24 authors, Claudia Bagni.
EMBO Mol Med, 2013 Oct 05; 5(10). PMID: 24092663    Free PMC article.
Novel modeling of cancer cell signaling pathways enables systematic drug repositioning for distinct breast cancer metastases.
Hong Zhao, Guangxu Jin, +9 authors, Stephen T C Wong.
Cancer Res, 2013 Oct 08; 73(20). PMID: 24097821    Free PMC article.
Concurrent gene signatures for han chinese breast cancers.
Chi-Cheng Huang, Shih-Hsin Tu, +5 authors, Eric Y Chuang.
PLoS One, 2013 Oct 08; 8(10). PMID: 24098497    Free PMC article.
Hybrid method for prediction of metastasis in breast cancer patients using gene expression signals.
Alireza Mehri Dehnavi, Mohammad Reza Sehhati, Hossein Rabbani.
J Med Signals Sens, 2013 Oct 08; 3(2). PMID: 24098861    Free PMC article.
Using protein interaction database and support vector machines to improve gene signatures for prediction of breast cancer recurrence.
Mohammad Reza Sehhati, Alireza Mehri Dehnavi, Hossein Rabbani, Shaghayegh Haghjoo Javanmard.
J Med Signals Sens, 2013 Oct 08; 3(2). PMID: 24098862    Free PMC article.
A robust prognostic signature for hormone-positive node-negative breast cancer.
Obi L Griffith, François Pepin, +4 authors, Joe W Gray.
Genome Med, 2013 Oct 12; 5(10). PMID: 24112773    Free PMC article.
Breast tumors with elevated expression of 1q candidate genes confer poor clinical outcome and sensitivity to Ras/PI3K inhibition.
Muthulakshmi Muthuswami, Vignesh Ramesh, +6 authors, Kumaresan Ganesan.
PLoS One, 2013 Oct 23; 8(10). PMID: 24147022    Free PMC article.
Long chain fatty Acyl-CoA synthetase 4 is a biomarker for and mediator of hormone resistance in human breast cancer.
Xinyu Wu, Yirong Li, +12 authors, Marie E Monaco.
PLoS One, 2013 Oct 25; 8(10). PMID: 24155918    Free PMC article.
An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk.
Christina Yau, John Sninsky, +9 authors, Christopher C Benz.
Breast Cancer Res, 2013 Nov 01; 15(5). PMID: 24172169    Free PMC article.
Wnt signaling in triple negative breast cancer is associated with metastasis.
Nandini Dey, Benjamin G Barwick, +11 authors, Brian R Leyland-Jones.
BMC Cancer, 2013 Nov 12; 13. PMID: 24209998    Free PMC article.
Highly Cited.
Association of osteopontin and cyclooxygenase-2 expression with breast cancer subtypes and their use as potential biomarkers.
Dhanashri Thorat, Asutosh Sahu, +6 authors, Gopal C Kundu.
Oncol Lett, 2013 Nov 22; 6(6). PMID: 24260046    Free PMC article.
Two-gene expression ratio as predictor for breast cancer treated with tamoxifen: evidence from meta-analysis.
Lin Zhao, Shimiao Zhu, Ying Gao, Yaogang Wang.
Tumour Biol, 2013 Nov 23; 35(4). PMID: 24264313
Ensemble classifier based on context specific miRNA regulation modules: a new method for cancer outcome prediction.
Xionghui Zhou, Juan Liu, +2 authors, Jianghui Xiong.
BMC Bioinformatics, 2013 Dec 07; 14 Suppl 12. PMID: 24268063    Free PMC article.
Pathway analyses and understanding disease associations.
Yu Liu, Mark R Chance.
Curr Genet Med Rep, 2013 Dec 10; 1(4). PMID: 24319650    Free PMC article.
An integrated systems genetics screen reveals the transcriptional structure of inherited predisposition to metastatic disease.
Farhoud Faraji, Ying Hu, +4 authors, Kent W Hunter.
Genome Res, 2013 Dec 11; 24(2). PMID: 24322557    Free PMC article.
Gene Expression Meta-Analysis Identifies Cytokine Pathways and 5q Aberrations Involved in Metastasis of ERBB2 Amplified and Basal Breast Cancer.
Mads Thomassen, Qihua Tan, Mark Burton, Torben A Kruse.
Cancer Inform, 2013 Dec 12; 12. PMID: 24327800    Free PMC article.
Omnibus risk assessment via accelerated failure time kernel machine modeling.
Jennifer A Sinnott, Tianxi Cai.
Biometrics, 2013 Dec 18; 69(4). PMID: 24328713    Free PMC article.
Gene expression profiles accurately predict outcome following liver resection in patients with metastatic colorectal cancer.
Hiromichi Ito, Qianxing Mo, +10 authors, Michael D'Angelica.
PLoS One, 2013 Dec 18; 8(12). PMID: 24339954    Free PMC article.
A prognostic gene signature for metastasis-free survival of triple negative breast cancer patients.
Unjin Lee, Casey Frankenberger, +6 authors, Marsha Rich Rosner.
PLoS One, 2013 Dec 19; 8(12). PMID: 24349199    Free PMC article.
Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition.
Gaofeng Xiong, Lei Deng, +2 authors, Ren Xu.
BMC Cancer, 2014 Jan 05; 14. PMID: 24383403    Free PMC article.
Highly Cited.
Current composite-feature classification methods do not outperform simple single-genes classifiers in breast cancer prognosis.
Christine Staiger, Sidney Cadot, +2 authors, Gunnar W Klau.
Front Genet, 2014 Jan 07; 4. PMID: 24391662    Free PMC article.
Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets.
Thalia A Farazi, Jelle J Ten Hoeve, +5 authors, Lodewyk F A Wessels.
Genome Biol, 2014 Jan 09; 15(1). PMID: 24398324    Free PMC article.
Boosting the concordance index for survival data--a unified framework to derive and evaluate biomarker combinations.
Andreas Mayr, Matthias Schmid.
PLoS One, 2014 Jan 09; 9(1). PMID: 24400093    Free PMC article.
Identification and validation of an anthracycline/cyclophosphamide-based chemotherapy response assay in breast cancer.
Jude M Mulligan, Laura A Hill, +21 authors, Richard D Kennedy.
J Natl Cancer Inst, 2014 Jan 10; 106(1). PMID: 24402422    Free PMC article.
A T cell gene expression panel for the diagnosis and monitoring of disease activity in patients with systemic lupus erythematosus.
Alexandros P Grammatikos, Vasileios C Kyttaris, +4 authors, George C Tsokos.
Clin Immunol, 2014 Jan 18; 150(2). PMID: 24434273    Free PMC article.
Elafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors.
S I Labidi-Galy, A Clauss, +14 authors, R Drapkin.
Oncogene, 2014 Jan 29; 34(3). PMID: 24469047    Free PMC article.
Regularized Multivariate Regression for Identifying Master Predictors with Application to Integrative Genomics Study of Breast Cancer.
Jie Peng, Ji Zhu, +4 authors, Pei Wang.
Ann Appl Stat, 2010 Mar 01; 4(1). PMID: 24489618    Free PMC article.
Integrative gene network construction to analyze cancer recurrence using semi-supervised learning.
Chihyun Park, Jaegyoon Ahn, Hyunjin Kim, Sanghyun Park.
PLoS One, 2014 Feb 06; 9(1). PMID: 24497942    Free PMC article.
Breast tumor subgroups reveal diverse clinical prognostic power.
Zhaoqi Liu, Xiang-Sun Zhang, Shihua Zhang.
Sci Rep, 2014 Feb 07; 4. PMID: 24499868    Free PMC article.
Novel roles for ERK5 and cofilin as critical mediators linking ERα-driven transcription, actin reorganization, and invasiveness in breast cancer.
Zeynep Madak-Erdogan, Rosa Ventrella, Luke Petry, Benita S Katzenellenbogen.
Mol Cancer Res, 2014 Feb 08; 12(5). PMID: 24505128    Free PMC article.
Decreased expression of Yes-associated protein is associated with outcome in the luminal A breast cancer subgroup and with an impaired tamoxifen response.
Sophie Lehn, Nicholas P Tobin, +4 authors, Göran Landberg.
BMC Cancer, 2014 Feb 25; 14. PMID: 24559095    Free PMC article.
RRHGE: a novel approach to classify the estrogen receptor based breast cancer subtypes.
Ashish Saini, Jingyu Hou, Wanlei Zhou.
ScientificWorldJournal, 2014 Feb 25; 2014. PMID: 24563630    Free PMC article.
Mining the tissue-tissue gene co-expression network for tumor microenvironment study and biomarker prediction.
Yang Xiang, Jie Zhang, Kun Huang.
BMC Genomics, 2014 Feb 26; 14 Suppl 5. PMID: 24564578    Free PMC article.
Molecular pathway identification using biological network-regularized logistic models.
Wen Zhang, Ying-Wooi Wan, +3 authors, Zhandong Liu.
BMC Genomics, 2014 Feb 26; 14 Suppl 8. PMID: 24564637    Free PMC article.
Wnt modulates MCL1 to control cell survival in triple negative breast cancer.
Lixin Yang, Aldwin Apollo Perez, +11 authors, Yun Yen.
BMC Cancer, 2014 Feb 26; 14. PMID: 24564888    Free PMC article.
A categorical network approach for discovering differentially expressed regulations in cancer.
Nikolay Balov.
BMC Med Genomics, 2014 Feb 26; 6 Suppl 3. PMID: 24565081    Free PMC article.
Good practice guidelines for biomarker discovery from array data: a case study for breast cancer prognosis.
Jie Cheng, Joel Greshock, +3 authors, Kwan Lee.
BMC Syst Biol, 2014 Feb 26; 7 Suppl 4. PMID: 24565120    Free PMC article.
E2/Estrogen receptor/sjogren syndrome-associated autoantigen relieves coactivator activator-induced G1/S arrest to promote breast tumorigenicity.
Yun Kyoung Kang, Sung Yun Jung, +4 authors, Bert W O'Malley.
Mol Cell Biol, 2014 Feb 26; 34(9). PMID: 24567374    Free PMC article.
A novel approach for discovering condition-specific correlations of gene expressions within biological pathways by using cloud computing technology.
Tzu-Hao Chang, Shih-Lin Wu, +2 authors, Cheng-Wei Chang.
Biomed Res Int, 2014 Mar 01; 2014. PMID: 24579087    Free PMC article.
Histone demethylase RBP2 is critical for breast cancer progression and metastasis.
Jian Cao, Zongzhi Liu, +6 authors, Qin Yan.
Cell Rep, 2014 Mar 04; 6(5). PMID: 24582965    Free PMC article.
A core invasiveness gene signature reflects epithelial-to-mesenchymal transition but not metastatic potential in breast cancer cell lines and tissue samples.
Melike Marsan, Gert Van den Eynden, +7 authors, Steven J Van Laere.
PLoS One, 2014 Mar 04; 9(2). PMID: 24586640    Free PMC article.
A personalized committee classification approach to improving prediction of breast cancer metastasis.
Md Jamiul Jahid, Tim H Huang, Jianhua Ruan.
Bioinformatics, 2014 Mar 13; 30(13). PMID: 24618465    Free PMC article.
A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity.
Ryan P McMullin, Ben S Wittner, +11 authors, Dennis C Sgroi.
Breast Cancer Res, 2014 Mar 15; 16(2). PMID: 24625110    Free PMC article.
Explaining additional genetic variation in complex traits.
Matthew R Robinson, Naomi R Wray, Peter M Visscher.
Trends Genet, 2014 Mar 19; 30(4). PMID: 24629526    Free PMC article.
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The overexpression of MCPH1 inhibits cell growth through regulating cell cycle-related proteins and activating cytochrome c-caspase 3 signaling in cervical cancer.
Li Mai, Faping Yi, +7 authors, Fangzhou Song.
Mol Cell Biochem, 2014 Mar 19; 392(1-2). PMID: 24633962
Inferring gene dependency network specific to phenotypic alteration based on gene expression data and clinical information of breast cancer.
Xionghui Zhou, Juan Liu.
PLoS One, 2014 Mar 19; 9(3). PMID: 24637666    Free PMC article.
Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status.
Xi Zhao, Einar Andreas Rødland, +5 authors, Anne-Lise Børresen-Dale.
BMC Cancer, 2014 Mar 22; 14. PMID: 24645668    Free PMC article.
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway.
Xi Chen, Dimitrios Iliopoulos, +21 authors, Laurie H Glimcher.
Nature, 2014 Mar 29; 508(7494). PMID: 24670641    Free PMC article.
Highly Cited.
Gasdermin-B promotes invasion and metastasis in breast cancer cells.
Marta Hergueta-Redondo, David Sarrió, +9 authors, Gema Moreno-Bueno.
PLoS One, 2014 Mar 29; 9(3). PMID: 24675552    Free PMC article.
Ferritin heavy chain in triple negative breast cancer: a favorable prognostic marker that relates to a cluster of differentiation 8 positive (CD8+) effector T-cell response.
Ning Qing Liu, Tommaso De Marchi, +13 authors, Arzu Umar.
Mol Cell Proteomics, 2014 Apr 20; 13(7). PMID: 24742827    Free PMC article.
On integrating multi-experiment microarray data.
Georgia Tsiliki, Dimitrios Vlachakis, Sophia Kossida.
Philos Trans A Math Phys Eng Sci, 2014 Apr 23; 372(2016). PMID: 24751870    Free PMC article.
Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer.
F Al-Ejeh, P T Simpson, +12 authors, K K Khanna.
Oncogenesis, 2014 Apr 23; 3. PMID: 24752235    Free PMC article.
Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.
Aaron B Krueger, David J Drasin, +17 authors, Rui Zhao.
J Biol Chem, 2014 Apr 24; 289(23). PMID: 24755226    Free PMC article.
OPG and PgR show similar cohort specific effects as prognostic factors in ER positive breast cancer.
Nicole Sänger, Eugen Ruckhäberle, +9 authors, Thomas Karn.
Mol Oncol, 2014 May 03; 8(7). PMID: 24785095    Free PMC article.
SPSB1 promotes breast cancer recurrence by potentiating c-MET signaling.
Yi Feng, Tien-Chi Pan, +4 authors, Lewis A Chodosh.
Cancer Discov, 2014 May 03; 4(7). PMID: 24786206    Free PMC article.
PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis.
A Paul, S Gunewardena, +11 authors, S Paul.
Cell Death Differ, 2014 May 03; 21(9). PMID: 24786829    Free PMC article.
Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer.
Christine Mehner, Alexandra Hockla, +3 authors, Evette S Radisky.
Oncotarget, 2014 May 09; 5(9). PMID: 24811362    Free PMC article.
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Overexpression of the EMT driver brachyury in breast carcinomas: association with poor prognosis.
Claudia Palena, Mario Roselli, +13 authors, Fiorella Guadagni.
J Natl Cancer Inst, 2014 May 13; 106(5). PMID: 24815864    Free PMC article.
MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.
Yubao Wang, Young-Mi Lee, +15 authors, Jean J Zhao.
Elife, 2014 May 23; 3. PMID: 24844244    Free PMC article.
Intra-tumoral Metastatic Double Primary Carcinoma: Synchronous Metastatic Tumor in Lung from Breast and Thyroid Carcinoma.
Lee Chun Park, Ji Yun Jeong, +4 authors, Yeon Hee Park.
Cancer Res Treat, 2014 May 23; 46(2). PMID: 24851113    Free PMC article.
Subtype-dependent prognostic relevance of an interferon-induced pathway metagene in node-negative breast cancer.
Maurizio Callari, Valeria Musella, +9 authors, Maria Grazia Daidone.
Mol Oncol, 2014 May 24; 8(7). PMID: 24853384    Free PMC article.
Importance of Breast Cancer Subtype in the Development of Androgen Receptor Directed Therapy.
Elgene Lim, Min Ni, +3 authors, Myles Brown.
Curr Breast Cancer Rep, 2014 May 27; 6(2). PMID: 24860642    Free PMC article.
Integration of mRNA expression profile, copy number alterations, and microRNA expression levels in breast cancer to improve grade definition.
Claudia Cava, Gloria Bertoli, +5 authors, Isabella Castiglioni.
PLoS One, 2014 May 29; 9(5). PMID: 24866763    Free PMC article.
Systematic pathway enrichment analysis of a genome-wide association study on breast cancer survival reveals an influence of genes involved in cell adhesion and calcium signaling on the patients' clinical outcome.
Andrea Woltmann, Bowang Chen, +11 authors, Asta Försti.
PLoS One, 2014 Jun 03; 9(6). PMID: 24886783    Free PMC article.
Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer.
Sakari Vanharanta, Christina B Marney, +5 authors, Joan Massagué.
Elife, 2014 Jun 06; 3. PMID: 24898756    Free PMC article.
Ensemble analyses improve signatures of tumour hypoxia and reveal inter-platform differences.
Natalie S Fox, Maud H W Starmans, +2 authors, Paul C Boutros.
BMC Bioinformatics, 2014 Jun 07; 15. PMID: 24902696    Free PMC article.
A 41-gene signature derived from breast cancer stem cells as a predictor of survival.
Zhi-Qiang Yin, Jian-Jun Liu, +9 authors, Hong-Xia Wang.
J Exp Clin Cancer Res, 2014 Jun 08; 33. PMID: 24906694    Free PMC article.
Mammary glands exhibit molecular laterality and undergo left-right asymmetric ductal epithelial growth in MMTV-cNeu mice.
J P Robichaux, R M Hallett, +2 authors, A F Ramsdell.
Oncogene, 2014 Jun 10; 34(15). PMID: 24909172    Free PMC article.
Bioinformatics for precision medicine in oncology: principles and application to the SHIVA clinical trial.
Nicolas Servant, Julien Roméjon, +20 authors, Philippe Hupé.
Front Genet, 2014 Jun 10; 5. PMID: 24910641    Free PMC article.
Review.
Increased macroH2A1.1 expression correlates with poor survival of triple-negative breast cancer patients.
Anne-Claire Lavigne, Magali Castells, +3 authors, Kerstin Bystricky.
PLoS One, 2014 Jun 10; 9(6). PMID: 24911873    Free PMC article.
Hydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer.
Katherine L Cook, Anni Wärri, +4 authors, Robert Clarke.
Clin Cancer Res, 2014 Jun 15; 20(12). PMID: 24928945    Free PMC article.
Breast cancer prognosis risk estimation using integrated gene expression and clinical data.
Ashish Saini, Jingyu Hou, Wanlei Zhou.
Biomed Res Int, 2014 Jun 21; 2014. PMID: 24949450    Free PMC article.
Validation of the prognostic gene portfolio, ClinicoMolecular Triad Classification, using an independent prospective breast cancer cohort and external patient populations.
Dong-Yu Wang, Susan J Done, David R Mc Cready, Wey L Leong.
Breast Cancer Res, 2014 Jul 06; 16(4). PMID: 24996446    Free PMC article.
Systematic analysis of metastasis-associated genes identifies miR-17-5p as a metastatic suppressor of basal-like breast cancer.
Meiyun Fan, Aarti Sethuraman, +2 authors, Lawrence M Pfeffer.
Breast Cancer Res Treat, 2014 Jul 09; 146(3). PMID: 25001613    Free PMC article.
Functional characterization of breast cancer using pathway profiles.
Feng Tian, Yajie Wang, Michael Seiler, Zhenjun Hu.
BMC Med Genomics, 2014 Jul 22; 7. PMID: 25041817    Free PMC article.
Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins.
Hani Goodarzi, Steven Zhang, +3 authors, Sohail F Tavazoie.
Nature, 2014 Jul 22; 513(7517). PMID: 25043050    Free PMC article.
A kernel-based multivariate feature selection method for microarray data classification.
Shiquan Sun, Qinke Peng, Adnan Shakoor.
PLoS One, 2014 Jul 23; 9(7). PMID: 25048512    Free PMC article.
A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype.
Qing Cheng, Jeffrey T Chang, +4 authors, H Kim Lyerly.
Breast Cancer Res, 2014 Jul 26; 16(4). PMID: 25060555    Free PMC article.
Más-o-menos: a simple sign averaging method for discrimination in genomic data analysis.
Sihai Dave Zhao, Giovanni Parmigiani, Curtis Huttenhower, Levi Waldron.
Bioinformatics, 2014 Jul 26; 30(21). PMID: 25061068    Free PMC article.
miR-206 inhibits cell migration through direct targeting of the actin-binding protein coronin 1C in triple-negative breast cancer.
Jun Wang, Efrosini Tsouko, +4 authors, Cecilia Williams.
Mol Oncol, 2014 Jul 31; 8(8). PMID: 25074552    Free PMC article.
Integrative analysis reveals disease-associated genes and biomarkers for prostate cancer progression.
Yin Li, Wanwipa Vongsangnak, Luonan Chen, Bairong Shen.
BMC Med Genomics, 2014 Aug 01; 7 Suppl 1. PMID: 25080090    Free PMC article.
ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.
Peijing Zhang, Yongkun Wei, +16 authors, Li Ma.
Nat Cell Biol, 2014 Aug 05; 16(9). PMID: 25086746    Free PMC article.
Highly Cited.
Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines.
Natascia Marino, Joshua W Collins, +8 authors, Patricia S Steeg.
Clin Exp Metastasis, 2014 Aug 05; 31(7). PMID: 25086928    Free PMC article.
Molecular pathogenesis of bone metastases in breast cancer: Proven and emerging therapeutic targets.
Nadia Rucci, Patrizia Sanità, +2 authors, Adriano Angelucci.
World J Clin Oncol, 2014 Aug 13; 5(3). PMID: 25114849    Free PMC article.
Review.
hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3.
Jason R Dobson, Hanna Taipaleenmäki, +6 authors, Jitesh Pratap.
Cancer Cell Int, 2014 Aug 15; 14. PMID: 25120384    Free PMC article.
Expression of ALDH1 and TGFβ2 in benign and malignant breast tumors and their prognostic implications.
Rongsheng Zheng, Jin Wang, +6 authors, Yan Yang.
Int J Clin Exp Pathol, 2014 Aug 15; 7(7). PMID: 25120797    Free PMC article.
Elevated APOBEC3B correlates with poor outcomes for estrogen-receptor-positive breast cancers.
Anieta M Sieuwerts, Scooter Willis, +11 authors, John W M Martens.
Horm Cancer, 2014 Aug 16; 5(6). PMID: 25123150    Free PMC article.
Highly Cited.
Gly322Asp and Asn127Ser single nucleotide polymorphisms (SNPs) of hMSH2 mismatch repair gene and the risk of triple-negative breast cancer in Polish women.
Beata Smolarz, Marianna Makowska, +2 authors, Hanna Romanowicz.
Fam Cancer, 2014 Aug 20; 14(1). PMID: 25134804    Free PMC article.
A program to identify prognostic and predictive gene signatures.
Sam D Chorlton, Robin M Hallett, John A Hassell.
BMC Res Notes, 2014 Aug 20; 7. PMID: 25135081    Free PMC article.
Age-specific changes in intrinsic breast cancer subtypes: a focus on older women.
Emily O Jenkins, Allison M Deal, +4 authors, Hyman B Muss.
Oncologist, 2014 Aug 22; 19(10). PMID: 25142841    Free PMC article.
Expression of nicotinamide phosphoribosyltransferase-influenced genes predicts recurrence-free survival in lung and breast cancers.
Tong Zhou, Ting Wang, Joe G N Garcia.
Sci Rep, 2014 Aug 26; 4. PMID: 25146220    Free PMC article.
Cancer progression modeling using static sample data.
Yijun Sun, Jin Yao, Norma J Nowak, Steve Goodison.
Genome Biol, 2014 Aug 27; 15(8). PMID: 25155694    Free PMC article.
A computational model to predict bone metastasis in breast cancer by integrating the dysregulated pathways.
Xionghui Zhou, Juan Liu.
BMC Cancer, 2014 Aug 29; 14. PMID: 25163697    Free PMC article.
Ceramide kinase promotes tumor cell survival and mammary tumor recurrence.
Ania W Payne, Dhruv K Pant, Tien-Chi Pan, Lewis A Chodosh.
Cancer Res, 2014 Aug 29; 74(21). PMID: 25164007    Free PMC article.
Systems consequences of amplicon formation in human breast cancer.
Koichiro Inaki, Francesca Menghi, +16 authors, Edison T Liu.
Genome Res, 2014 Sep 05; 24(10). PMID: 25186909    Free PMC article.
An improved syngeneic orthotopic murine model of human breast cancer progression.
Omar M Rashid, Masayuki Nagahashi, +7 authors, Kazuaki Takabe.
Breast Cancer Res Treat, 2014 Sep 10; 147(3). PMID: 25200444    Free PMC article.
Microarray phosphatome profiling of breast cancer patients unveils a complex phosphatase regulatory role of the MAPK and PI3K pathways in estrogen receptor-negative breast cancers.
Ramon G Manzano, Elena M Martinez-Navarro, Jeronimo Forteza, Antonio Brugarolas.
Int J Oncol, 2014 Sep 10; 45(6). PMID: 25201346    Free PMC article.
Prognostic and therapeutic significance of ribonucleotide reductase small subunit M2 in estrogen-negative breast cancers.
Hang Zhang, Xiyong Liu, +7 authors, Yun Yen.
BMC Cancer, 2014 Sep 13; 14. PMID: 25213022    Free PMC article.
A generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling.
Romain Boidot, Samuel Branders, +3 authors, Olivier Feron.
Oncotarget, 2014 Sep 13; 5(16). PMID: 25216520    Free PMC article.
A novel model to combine clinical and pathway-based transcriptomic information for the prognosis prediction of breast cancer.
Sijia Huang, Cameron Yee, +2 authors, Lana X Garmire.
PLoS Comput Biol, 2014 Sep 19; 10(9). PMID: 25233347    Free PMC article.
Androgen receptor genomic regulation.
Hong-Jian Jin, Jung Kim, Jindan Yu.
Transl Androl Urol, 2014 Sep 23; 2(3). PMID: 25237629    Free PMC article.
ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling.
Rumela Chakrabarti, Yong Wei, +13 authors, Yibin Kang.
Nat Cell Biol, 2014 Sep 23; 16(10). PMID: 25241036    Free PMC article.
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Functional Genomics and a New Era in Radiation Biology and Oncology.
Sally A Amundson.
Bioscience, 2008 Jun 01; 58(6). PMID: 25249699    Free PMC article.
Claudin-low breast cancers: clinical, pathological, molecular and prognostic characterization.
Renaud Sabatier, Pascal Finetti, +5 authors, François Bertucci.
Mol Cancer, 2014 Oct 04; 13. PMID: 25277734    Free PMC article.
Invasive lobular breast cancer: the prognostic impact of histopathological grade, E-cadherin and molecular subtypes.
Monica J Engstrøm, Signe Opdahl, +2 authors, Anna M Bofin.
Histopathology, 2014 Oct 07; 66(3). PMID: 25283075    Free PMC article.
Algorithms for Discovery of Multiple Markov Boundaries.
Alexander Statnikov, Nikita I Lytkin, Jan Lemeire, Constantin F Aliferis.
J Mach Learn Res, 2013 Feb 01; 14. PMID: 25285052    Free PMC article.
Network-based Pathway Enrichment Analysis.
Lu Liu, Jianhua Ruan.
Proceedings (IEEE Int Conf Bioinformatics Biomed), 2013 Jan 01;. PMID: 25327472    Free PMC article.
Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells.
Linn-Karina M Selvik, Shalini Rao, +6 authors, Liv Thommesen.
PLoS One, 2014 Nov 11; 9(11). PMID: 25384047    Free PMC article.
Predicting cancer prognosis using functional genomics data sets.
Jishnu Das, Kaitlyn M Gayvert, Haiyuan Yu.
Cancer Inform, 2014 Nov 14; 13(Suppl 5). PMID: 25392695    Free PMC article.
Review.
Shift in GATA3 functions, and GATA3 mutations, control progression and clinical presentation in breast cancer.
Helit Cohen, Rotem Ben-Hamo, +4 authors, Sol Efroni.
Breast Cancer Res, 2014 Nov 21; 16(6). PMID: 25410484    Free PMC article.
Animal models for exploring the pharmacokinetics of breast cancer therapies.
Omar M Rashid, Kazuaki Takabe.
Expert Opin Drug Metab Toxicol, 2014 Nov 25; 11(2). PMID: 25416501    Free PMC article.
Review.
Estrogen independent gene expression defines clinically relevant subgroups of estrogen receptor positive breast cancer.
Robin M Hallett, John A Hassell.
BMC Cancer, 2014 Nov 26; 14. PMID: 25420785    Free PMC article.
E2F4 regulatory program predicts patient survival prognosis in breast cancer.
Sari S Khaleel, Erik H Andrews, +2 authors, Chao Cheng.
Breast Cancer Res, 2014 Dec 03; 16(6). PMID: 25440089    Free PMC article.
Pathway activity inference for multiclass disease classification through a mathematical programming optimisation framework.
Lingjian Yang, Chrysanthi Ainali, Sophia Tsoka, Lazaros G Papageorgiou.
BMC Bioinformatics, 2014 Dec 06; 15. PMID: 25475756    Free PMC article.
The value of multigene predictors of clinical outcome in breast cancer: an analysis of the evidence.
Amalia M Issa, Vivek S Chaudhari, Gary E Marchant.
Expert Rev Mol Diagn, 2014 Dec 06; 15(2). PMID: 25479414    Free PMC article.
Review.
Prognostic influence of cyclooxygenase-2 protein and mRNA expression in node-negative breast cancer patients.
Isabel Sicking, Karlien Rommens, +7 authors, Marcus Schmidt.
BMC Cancer, 2014 Dec 17; 14. PMID: 25511800    Free PMC article.
The SIX1-EYA transcriptional complex as a therapeutic target in cancer.
Melanie A Blevins, Christina G Towers, +2 authors, Heide L Ford.
Expert Opin Ther Targets, 2015 Jan 04; 19(2). PMID: 25555392    Free PMC article.
Review.
Predicting 5-Year Survival Status of Patients with Breast Cancer based on Supervised Wavelet Method.
Maryam Farhadian, Hossein Mahjub, +2 authors, Muharram Mansoorizadeh.
Osong Public Health Res Perspect, 2015 Jan 07; 5(6). PMID: 25562040    Free PMC article.
Distance-based classifiers as potential diagnostic and prediction tools for human diseases.
Boris Veytsman, Lei Wang, +2 authors, Ancha Baranova.
BMC Genomics, 2015 Jan 08; 15 Suppl 12. PMID: 25563076    Free PMC article.
Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate.
Jessica L Schwartz-Roberts, Katherine L Cook, +9 authors, Robert Clarke.
Cancer Res, 2015 Jan 13; 75(6). PMID: 25576084    Free PMC article.
T-ReCS: stable selection of dynamically formed groups of features with application to prediction of clinical outcomes.
Grace T Huang, Ioannis Tsamardinos, +2 authors, Panayiotis V Benos.
Pac Symp Biocomput, 2015 Jan 17;. PMID: 25592602    Free PMC article.
Expression profiling of migrated and invaded breast cancer cells predicts early metastatic relapse and reveals Krüppel-like factor 9 as a potential suppressor of invasive growth in breast cancer.
Ridha Limame, Ken Op de Beeck, +8 authors, Patrick Pauwels.
Oncoscience, 2015 Jan 17; 1(1). PMID: 25593984    Free PMC article.
Stimulation of hERG1 channel activity promotes a calcium-dependent degradation of cyclin E2, but not cyclin E1, in breast cancer cells.
Mathew Perez-Neut, Andrew Shum, +2 authors, Saverio Gentile.
Oncotarget, 2015 Jan 19; 6(3). PMID: 25596745    Free PMC article.
Jumping on the Train of Personalized Medicine: A Primer for Non- Geneticist Clinicians: Part 3. Clinical Applications in the Personalized Medicine Area.
Aihua Li, David Meyre.
Curr Psychiatry Rev, 2015 Jan 20; 10(2). PMID: 25598768    Free PMC article.
A permutation method to assess heterogeneity in external validation for risk prediction models.
Ling-Yi Wang, Wen-Chung Lee.
PLoS One, 2015 Jan 22; 10(1). PMID: 25606854    Free PMC article.
Prognostic significance of minichromosome maintenance proteins in breast cancer.
Hang Fai Kwok, Shu-Dong Zhang, +5 authors, Kelvin Yuen-Kwong Chan.
Am J Cancer Res, 2015 Jan 30; 5(1). PMID: 25628920    Free PMC article.
DC-SCRIPT is a novel regulator of the tumor suppressor gene CDKN2B and induces cell cycle arrest in ERα-positive breast cancer cells.
Marleen Ansems, Jonas Nørskov Søndergaard, +8 authors, Gosse J Adema.
Breast Cancer Res Treat, 2015 Feb 11; 149(3). PMID: 25663546    Free PMC article.
Transcriptome meta-analysis reveals dysregulated pathways in nasopharyngeal carcinoma.
Warut Tulalamba, Noppadol Larbcharoensub, +2 authors, Tavan Janvilisri.
Tumour Biol, 2015 Mar 01; 36(8). PMID: 25724187
Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease.
Maurice P H M Jansen, Leen Sas, +20 authors, Steven Van Laere.
Mol Oncol, 2015 Mar 17; 9(6). PMID: 25771305    Free PMC article.
GPNMB cooperates with neuropilin-1 to promote mammary tumor growth and engages integrin α5β1 for efficient breast cancer metastasis.
G Maric, M G Annis, +7 authors, P M Siegel.
Oncogene, 2015 Mar 17; 34(43). PMID: 25772243
Tumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant.
Wies van Roosmalen, Sylvia E Le Dévédec, +15 authors, Bob van de Water.
J Clin Invest, 2015 Mar 17; 125(4). PMID: 25774502    Free PMC article.
Highly Cited.
Comprehensive evaluation of composite gene features in cancer outcome prediction.
Dezhi Hou, Mehmet Koyutürk.
Cancer Inform, 2014 Jan 01; 13(Suppl 3). PMID: 25780335    Free PMC article.
Intra-tumour signalling entropy determines clinical outcome in breast and lung cancer.
Christopher R S Banerji, Simone Severini, Carlos Caldas, Andrew E Teschendorff.
PLoS Comput Biol, 2015 Mar 21; 11(3). PMID: 25793737    Free PMC article.
BioXpress: an integrated RNA-seq-derived gene expression database for pan-cancer analysis.
Quan Wan, Hayley Dingerdissen, +6 authors, Raja Mazumder.
Database (Oxford), 2015 Mar 31; 2015. PMID: 25819073    Free PMC article.
Retrospective analysis of metastatic behaviour of breast cancer subtypes.
C Dilara Savci-Heijink, Hans Halfwerk, +3 authors, Marc J van de Vijver.
Breast Cancer Res Treat, 2015 Mar 31; 150(3). PMID: 25820592    Free PMC article.
Identification of therapeutic targets for breast cancer using biological informatics methods.
Xuejian Liu, Yongzhen Ma, +3 authors, Xiangli Chen.
Mol Med Rep, 2015 Apr 01; 12(2). PMID: 25824986    Free PMC article.
Prognostic stromal gene signatures in breast cancer.
Sofia Winslow, Karin Leandersson, Anders Edsjö, Christer Larsson.
Breast Cancer Res, 2015 Apr 08; 17. PMID: 25848820    Free PMC article.
Identification of molecular determinants of primary and metastatic tumour re-initiation in breast cancer.
Jason B Ross, Doowon Huh, Lisa B Noble, Sohail F Tavazoie.
Nat Cell Biol, 2015 Apr 14; 17(5). PMID: 25866923    Free PMC article.
TGIF governs a feed-forward network that empowers Wnt signaling to drive mammary tumorigenesis.
Ming-Zhu Zhang, Olivier Ferrigno, +10 authors, Azeddine Atfi.
Cancer Cell, 2015 Apr 16; 27(4). PMID: 25873176    Free PMC article.
Integrative analysis of survival-associated gene sets in breast cancer.
Frederick S Varn, Matthew H Ung, Shao Ke Lou, Chao Cheng.
BMC Med Genomics, 2015 Apr 17; 8. PMID: 25881247    Free PMC article.
YY1 suppresses FEN1 over-expression and drug resistance in breast cancer.
Jianwei Wang, Lina Zhou, +14 authors, Binghui Shen.
BMC Cancer, 2015 Apr 18; 15. PMID: 25885449    Free PMC article.
Denoising perturbation signatures reveal an actionable AKT-signaling gene module underlying a poor clinical outcome in endocrine-treated ER+ breast cancer.
Andrew E Teschendorff, Linlin Li, Zhen Yang.
Genome Biol, 2015 Apr 18; 16. PMID: 25886003    Free PMC article.
Evaluation of public cancer datasets and signatures identifies TP53 mutant signatures with robust prognostic and predictive value.
Brian David Lehmann, Yan Ding, +6 authors, Yajun Yi.
BMC Cancer, 2015 Apr 18; 15. PMID: 25886164    Free PMC article.
ADAM12-L is a direct target of the miR-29 and miR-200 families in breast cancer.
Sara Duhachek-Muggy, Anna Zolkiewska.
BMC Cancer, 2015 Apr 18; 15. PMID: 25886595    Free PMC article.
Long non-coding RNA expression profiles predict metastasis in lymph node-negative breast cancer independently of traditional prognostic markers.
Kristina P Sørensen, Mads Thomassen, +5 authors, Torben A Kruse.
Breast Cancer Res, 2015 Apr 19; 17. PMID: 25887545    Free PMC article.
ENCAPP: elastic-net-based prognosis prediction and biomarker discovery for human cancers.
Jishnu Das, Kaitlyn M Gayvert, +2 authors, Haiyuan Yu.
BMC Genomics, 2015 Apr 19; 16. PMID: 25887568    Free PMC article.
One-step extrapolation of the prediction performance of a gene signature derived from a small study.
Ling-Yi Wang, Wen-Chung Lee.
BMJ Open, 2015 Apr 19; 5(4). PMID: 25888476    Free PMC article.
Fuzzy logic selection as a new reliable tool to identify molecular grade signatures in breast cancer--the INNODIAG study.
Tatiana Kempowsky-Hamon, Carine Valle, +12 authors, Véronique Anton-Leberre.
BMC Med Genomics, 2015 Apr 19; 8. PMID: 25888889    Free PMC article.
Altered Sirtuin 7 Expression is Associated with Early Stage Breast Cancer.
Ahmad Aljada, Ayman M Saleh, +3 authors, Amre Nasr.
Breast Cancer (Auckl), 2015 Apr 30; 9. PMID: 25922576    Free PMC article.
Chromosomal instability as a prognostic marker in cervical cancer.
Christine How, Jeff Bruce, +9 authors, Fei-Fei Liu.
BMC Cancer, 2015 May 07; 15. PMID: 25944123    Free PMC article.
The role of epigenetics in personalized medicine: challenges and opportunities.
Mahmood Rasool, Arif Malik, +9 authors, Siew Gan.
BMC Med Genomics, 2015 May 09; 8 Suppl 1. PMID: 25951941    Free PMC article.
Review.
Coordinated epigenetic remodelling of transcriptional networks occurs during early breast carcinogenesis.
Warwick J Locke, Elena Zotenko, +6 authors, Susan J Clark.
Clin Epigenetics, 2015 May 12; 7. PMID: 25960784    Free PMC article.
Notch promotes recurrence of dormant tumor cells following HER2/neu-targeted therapy.
Daniel L Abravanel, George K Belka, +4 authors, Lewis A Chodosh.
J Clin Invest, 2015 May 12; 125(6). PMID: 25961456    Free PMC article.
Pathway-based personalized analysis of breast cancer expression data.
Anna Livshits, Anna Git, +2 authors, Eytan Domany.
Mol Oncol, 2015 May 13; 9(7). PMID: 25963740    Free PMC article.
Overexpression of chromosome 14 open reading frame 166 correlates with disease progression and poorer prognosis in human NPC.
Lin Yang, Fengyan Li, +4 authors, Yong Chen.
Tumour Biol, 2015 May 13; 36(10). PMID: 25964093
Revisiting the transcriptional analysis of primary tumours and associated nodal metastases with enhanced biological and statistical controls: application to thyroid cancer.
M Tarabichi, M Saiselet, +5 authors, V Detours.
Br J Cancer, 2015 May 13; 112(10). PMID: 25965298    Free PMC article.
Development and validation of a novel platform-independent metastasis signature in human breast cancer.
Shuang G Zhao, Mark Shilkrut, +5 authors, Felix Y Feng.
PLoS One, 2015 May 15; 10(5). PMID: 25974184    Free PMC article.
Gene profiling and circulating tumor cells as biomarker to prognostic of patients with locoregional breast cancer.
Renata K Kuniyoshi, Flávia de Sousa Gehrke, +6 authors, Auro Del Giglio.
Tumour Biol, 2015 May 16; 36(10). PMID: 25976504
Prediction of early breast cancer metastasis from DNA microarray data using high-dimensional cox regression models.
Christophe Zemmour, François Bertucci, +4 authors, Jean-Marie Boher.
Cancer Inform, 2015 May 20; 14(Suppl 2). PMID: 25983547    Free PMC article.
KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer.
A T Alshareeda, O H Negm, +7 authors, E A Rakha.
Br J Cancer, 2015 May 20; 112(12). PMID: 25989275    Free PMC article.
Identification and evaluation of network modules for the prognosis of basal-like breast cancer.
Robin M Hallett, Jessica G Cockburn, +3 authors, Anita Bane.
Oncotarget, 2015 May 21; 6(19). PMID: 25991675    Free PMC article.
Monocytes and macrophages, implications for breast cancer migration and stem cell-like activity and treatment.
Rebecca Ward, Andrew H Sims, +8 authors, Rebecca Lamb.
Oncotarget, 2015 May 27; 6(16). PMID: 26008983    Free PMC article.
BRCC3 acts as a prognostic marker in nasopharyngeal carcinoma patients treated with radiotherapy and mediates radiation resistance in vitro.
Ziwei Tu, Bingqing Xu, +11 authors, Yunfei Xia.
Radiat Oncol, 2015 May 31; 10. PMID: 26024915    Free PMC article.
Presence of insulin-like growth factor binding proteins correlates with tumor-promoting effects of matrix metalloproteinase 9 in breast cancer.
Jae-Hyun Park, Morten Grønbech Rasch, +2 authors, Mikala Egeblad.
Neoplasia, 2015 May 31; 17(5). PMID: 26025665    Free PMC article.
Down-regulation of programmed cell death 4 (PDCD4) is associated with aromatase inhibitor resistance and a poor prognosis in estrogen receptor-positive breast cancer.
Zhike Chen, Yate-Ching Yuan, +3 authors, Shiuan Chen.
Breast Cancer Res Treat, 2015 Jun 01; 152(1). PMID: 26026468    Free PMC article.
Integrative correlation: Properties and relation to canonical correlations.
Leslie Cope, Daniel Q Naiman, Giovanni Parmigiani.
J Multivar Anal, 2014 Jan 01; 123. PMID: 26028790    Free PMC article.
Identification association of drug-disease by using functional gene module for breast cancer.
Lida Zhu, Fuxi Zhu.
BMC Med Genomics, 2015 Jun 06; 8 Suppl 2. PMID: 26045063    Free PMC article.
Gene Expression Signatures Based on Variability can Robustly Predict Tumor Progression and Prognosis.
Wikum Dinalankara, Héctor Corrada Bravo.
Cancer Inform, 2015 Jun 17; 14. PMID: 26078586    Free PMC article.
Association of Protein Translation and Extracellular Matrix Gene Sets with Breast Cancer Metastasis: Findings Uncovered on Analysis of Multiple Publicly Available Datasets Using Individual Patient Data Approach.
Nilotpal Chowdhury, Shantanu Sapru.
PLoS One, 2015 Jun 17; 10(6). PMID: 26080057    Free PMC article.
Co-modulation analysis of gene regulation in breast cancer reveals complex interplay between ESR1 and ERBB2 genes.
Yu-Chiao Chiu, Chin-Ting Wu, +4 authors, Eric Y Chuang.
BMC Genomics, 2015 Jun 24; 16 Suppl 7. PMID: 26100352    Free PMC article.
Multiple signatures of a disease in potential biomarker space: Getting the signatures consensus and identification of novel biomarkers.
Ghim Siong Ow, Vladimir A Kuznetsov.
BMC Genomics, 2015 Jun 24; 16 Suppl 7. PMID: 26100469    Free PMC article.
Expression of Notch1 Correlates with Breast Cancer Progression and Prognosis.
Xun Yuan, Mingsheng Zhang, +6 authors, Kongming Wu.
PLoS One, 2015 Jun 30; 10(6). PMID: 26121683    Free PMC article.
Enhancing the Lasso Approach for Developing a Survival Prediction Model Based on Gene Expression Data.
Shuhei Kaneko, Akihiro Hirakawa, Chikuma Hamada.
Comput Math Methods Med, 2015 Jul 07; 2015. PMID: 26146513    Free PMC article.
Inferring interaction type in gene regulatory networks using co-expression data.
Pegah Khosravi, Vahid H Gazestani, +4 authors, Gary D Bader.
Algorithms Mol Biol, 2015 Jul 15; 10. PMID: 26157474    Free PMC article.
Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness.
Gorka Ruiz de Garibay, Carmen Herranz, +36 authors, Miguel Angel Pujana.
PLoS One, 2015 Jul 15; 10(7). PMID: 26167915    Free PMC article.
MDA-MB-231 breast cancer cells overexpressing single VEGF isoforms display distinct colonisation characteristics.
Melanie Di Benedetto, Aurore Toullec, +7 authors, Martine Perrot-Applanat.
Br J Cancer, 2015 Jul 22; 113(5). PMID: 26196186    Free PMC article.
The prognostic significance of protein tyrosine phosphatase 4A2 in breast cancer.
Duanzheng Zhao, Libin Guo, +8 authors, Yao Lin.
Onco Targets Ther, 2015 Jul 24; 8. PMID: 26203261    Free PMC article.
Systems biology approach to studying proliferation-dependent prognostic subnetworks in breast cancer.
Qianqian Song, Hongyan Wang, +4 authors, Xiaobo Zhou.
Sci Rep, 2015 Aug 11; 5. PMID: 26257336    Free PMC article.
A novel HMGA1-CCNE2-YAP axis regulates breast cancer aggressiveness.
Silvia Pegoraro, Gloria Ros, +3 authors, Guidalberto Manfioletti.
Oncotarget, 2015 Aug 13; 6(22). PMID: 26265440    Free PMC article.
Biological and Clinical Significance of MAD2L1 and BUB1, Genes Frequently Appearing in Expression Signatures for Breast Cancer Prognosis.
Zhanwei Wang, Dionyssios Katsaros, +7 authors, Herbert Yu.
PLoS One, 2015 Aug 20; 10(8). PMID: 26287798    Free PMC article.
Spatiotemporal control of estrogen-responsive transcription in ERα-positive breast cancer cells.
P-Y Hsu, H-K Hsu, +9 authors, T H-M Huang.
Oncogene, 2015 Aug 25; 35(18). PMID: 26300005    Free PMC article.
ATAD2 overexpression links to enrichment of B-MYB-translational signatures and development of aggressive endometrial carcinoma.
Camilla Krakstad, Ingvild L Tangen, +12 authors, Helga B Salvesen.
Oncotarget, 2015 Aug 27; 6(29). PMID: 26308378    Free PMC article.
RKIP Inhibits Local Breast Cancer Invasion by Antagonizing the Transcriptional Activation of MMP13.
Ila Datar, Jingwei Feng, +12 authors, Kam C Yeung.
PLoS One, 2015 Aug 27; 10(8). PMID: 26308852    Free PMC article.
NETWORK-REGULARIZED HIGH-DIMENSIONAL COX REGRESSION FOR ANALYSIS OF GENOMIC DATA.
Hokeun Sun, Wei Lin, Rui Feng, Hongzhe Li.
Stat Sin, 2015 Sep 01; 24(3). PMID: 26316678    Free PMC article.
Boosting for high-dimensional two-class prediction.
Rok Blagus, Lara Lusa.
BMC Bioinformatics, 2015 Sep 24; 16. PMID: 26390865    Free PMC article.
APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer.
Manikandan Periyasamy, Hetal Patel, +17 authors, Simak Ali.
Cell Rep, 2015 Sep 29; 13(1). PMID: 26411678    Free PMC article.
The influence of cancer tissue sampling on the identification of cancer characteristics.
Hui Xu, Xin Guo, +7 authors, Wenyuan Zhao.
Sci Rep, 2015 Oct 23; 5. PMID: 26490514    Free PMC article.
Comparative study of joint analysis of microarray gene expression data in survival prediction and risk assessment of breast cancer patients.
Haleh Yasrebi.
Brief Bioinform, 2015 Oct 28; 17(5). PMID: 26504096    Free PMC article.
Tamoxifen therapy benefit predictive signature coupled with prognostic signature of post-operative recurrent risk for early stage ER+ breast cancer.
Hao Cai, Xiangyu Li, +6 authors, Zheng Guo.
Oncotarget, 2015 Nov 04; 6(42). PMID: 26527319    Free PMC article.
Joint use of over- and under-sampling techniques and cross-validation for the development and assessment of prediction models.
Rok Blagus, Lara Lusa.
BMC Bioinformatics, 2015 Nov 06; 16. PMID: 26537827    Free PMC article.
Ell3 stabilizes p53 following CDDP treatment via its effects on ubiquitin-dependent and -independent proteasomal degradation pathways in breast cancer cells.
Hee-Jin Ahn, Kwang-Soo Kim, +9 authors, Kyung-Soon Park.
Oncotarget, 2015 Nov 06; 6(42). PMID: 26540344    Free PMC article.
Understanding drugs in breast cancer through drug sensitivity screening.
Katharina Uhr, Wendy J C Prager-van der Smissen, +6 authors, John W M Martens.
Springerplus, 2015 Nov 07; 4. PMID: 26543746    Free PMC article.
E2f3 in tumor macrophages promotes lung metastasis.
P Trikha, N Sharma, +9 authors, G Leone.
Oncogene, 2015 Nov 10; 35(28). PMID: 26549026    Free PMC article.
A potential prognostic long non-coding RNA signature to predict metastasis-free survival of breast cancer patients.
Jie Sun, Xihai Chen, +5 authors, Meng Zhou.
Sci Rep, 2015 Nov 10; 5. PMID: 26549855    Free PMC article.
Highly Cited.
LINC00472 expression is regulated by promoter methylation and associated with disease-free survival in patients with grade 2 breast cancer.
Yi Shen, Zhanwei Wang, +6 authors, Herbert Yu.
Breast Cancer Res Treat, 2015 Nov 14; 154(3). PMID: 26564482    Free PMC article.
Using second harmonic generation to predict patient outcome in solid tumors.
K Burke, M Smid, +6 authors, E Brown.
BMC Cancer, 2015 Nov 26; 15. PMID: 26603532    Free PMC article.
High Expression of Three-Gene Signature Improves Prediction of Relapse-Free Survival in Estrogen Receptor-Positive and Node-Positive Breast Tumors.
Arvind Thakkar, Hemanth Raj, +3 authors, Muralidhara Padigaru.
Biomark Insights, 2015 Dec 10; 10. PMID: 26648682    Free PMC article.
Expression of a-Tocopherol-Associated protein (TAP) is associated with clinical outcome in breast cancer patients.
Xi Wang, Brian Z Ring, +5 authors, Shuyuan Yeh.
BMC Clin Pathol, 2015 Dec 15; 15. PMID: 26664297    Free PMC article.
Breast cancer intrinsic subtype classification, clinical use and future trends.
Xiaofeng Dai, Ting Li, +4 authors, Bozhi Shi.
Am J Cancer Res, 2015 Dec 23; 5(10). PMID: 26693050    Free PMC article.
Highly Cited. Review.
TGFβ isoforms and receptors mRNA expression in breast tumours: prognostic value and clinical implications.
Chenfeng Chen, Kong-Nan Zhao, +4 authors, Luis Vitetta.
BMC Cancer, 2015 Dec 26; 15. PMID: 26703884    Free PMC article.
Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles.
Frederick S Varn, Erik H Andrews, David W Mullins, Chao Cheng.
Nat Commun, 2016 Jan 05; 7. PMID: 26725977    Free PMC article.
The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl.
Jennifer L Dine, Ciara C O'Sullivan, +11 authors, Stanley Lipkowitz.
Breast Cancer Res Treat, 2016 Jan 14; 155(2). PMID: 26759246    Free PMC article.
Targeting the Notch signaling pathway in cancer therapeutics.
Huajiao Guo, Yi Lu, +5 authors, Jian Zhang.
Thorac Cancer, 2014 Nov 01; 5(6). PMID: 26767041    Free PMC article.
Review.
Iteratively refining breast cancer intrinsic subtypes in the METABRIC dataset.
Heloisa H Milioli, Renato Vimieiro, +3 authors, Pablo Moscato.
BioData Min, 2016 Jan 16; 9. PMID: 26770261    Free PMC article.
p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer.
Emily Powell, Jiansu Shao, +11 authors, Helen Piwnica-Worms.
Breast Cancer Res, 2016 Jan 29; 18(1). PMID: 26818199    Free PMC article.
G0S2 Suppresses Oncogenic Transformation by Repressing a MYC-Regulated Transcriptional Program.
Christina Y Yim, David J Sekula, +6 authors, Michael J Spinella.
Cancer Res, 2016 Feb 04; 76(5). PMID: 26837760    Free PMC article.
A function-blocking CD47 antibody suppresses stem cell and EGF signaling in triple-negative breast cancer.
Sukhbir Kaur, Abdel G Elkahloun, +8 authors, David D Roberts.
Oncotarget, 2016 Feb 04; 7(9). PMID: 26840086    Free PMC article.
Overexpression of Kinesin Associated Protein 3 (KIFAP3) in Breast Cancer.
Deepthi Telikicherla, Jagadeesha Maharudraiah, +5 authors, Akhilesh Pandey.
J Proteomics Bioinform, 2012 May 01; 5(5). PMID: 26843789    Free PMC article.
Enrichment of CD44 in basal-type breast cancer correlates with EMT, cancer stem cell gene profile, and prognosis.
Hanxiao Xu, Yijun Tian, +5 authors, Kongming Wu.
Onco Targets Ther, 2016 Feb 09; 9. PMID: 26855592    Free PMC article.
Distinct lymphocyte antigens 6 (Ly6) family members Ly6D, Ly6E, Ly6K and Ly6H drive tumorigenesis and clinical outcome.
Linlin Luo, Peter McGarvey, +3 authors, Geeta Upadhyay.
Oncotarget, 2016 Feb 11; 7(10). PMID: 26862846    Free PMC article.
An 8-gene mRNA expression profile in circulating tumor cells predicts response to aromatase inhibitors in metastatic breast cancer patients.
Esther A Reijm, Anieta M Sieuwerts, +17 authors, Stefan Sleijfer.
BMC Cancer, 2016 Feb 20; 16. PMID: 26892682    Free PMC article.
Interleukin-6 is a potential therapeutic target in interleukin-6 dependent, estrogen receptor-α-positive breast cancer.
Tineke Casneuf, Amy E Axel, +6 authors, A Kate Sasser.
Breast Cancer (Dove Med Press), 2016 Feb 20; 8. PMID: 26893580    Free PMC article.
Unbiased Prediction and Feature Selection in High-Dimensional Survival Regression.
Michael Laimighofer, Jan Krumsiek, Florian Buettner, Fabian J Theis.
J Comput Biol, 2016 Feb 20; 23(4). PMID: 26894327    Free PMC article.
Low Concordance between Gene Expression Signatures in ER Positive HER2 Negative Breast Carcinoma Could Impair Their Clinical Application.
Enora Laas, Peter Mallon, +3 authors, Fabien Reyal.
PLoS One, 2016 Feb 20; 11(2). PMID: 26895349    Free PMC article.
Regularized logistic regression with network-based pairwise interaction for biomarker identification in breast cancer.
Meng-Yun Wu, Xiao-Fei Zhang, +3 authors, Hong Yan.
BMC Bioinformatics, 2016 Feb 28; 17. PMID: 26921029    Free PMC article.
Gene modules associated with breast cancer distant metastasis-free survival in the PAM50 molecular subtypes.
Rong Liu, Wei Zhang, Zhao-Qian Liu, Hong-Hao Zhou.
Oncotarget, 2016 Mar 05; 7(16). PMID: 26934123    Free PMC article.
A BRCA1 deficient, NFκB driven immune signal predicts good outcome in triple negative breast cancer.
Niamh E Buckley, Paula Haddock, +6 authors, Paul Mullan.
Oncotarget, 2016 Mar 05; 7(15). PMID: 26943587    Free PMC article.
Differential network analysis reveals the genome-wide landscape of estrogen receptor modulation in hormonal cancers.
Tzu-Hung Hsiao, Yu-Chiao Chiu, +6 authors, Yidong Chen.
Sci Rep, 2016 Mar 15; 6. PMID: 26972162    Free PMC article.
Clinically available RNA profiling tests of prostate tumors: utility and comparison.
Rong Na, Yishuo Wu, Qiang Ding, Jianfeng Xu.
Asian J Androl, 2016 Mar 16; 18(4). PMID: 26975490    Free PMC article.
Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers.
Suryatheja Ananthula, Abhilasha Sinha, +5 authors, Wael M ElShamy.
Oncotarget, 2016 Mar 19; 7(15). PMID: 26989079    Free PMC article.
Overexpression of Ran GTPase Components Regulating Nuclear Export, but not Mitotic Spindle Assembly, Marks Chromosome Instability and Poor Prognosis in Breast Cancer.
Srividya Vaidyanathan, Pulari U Thangavelu, Pascal H G Duijf.
Target Oncol, 2016 Mar 30; 11(5). PMID: 27023921
Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cells.
Qiong Wu, Soni Sharma, +5 authors, Anthony N Imbalzano.
Oncotarget, 2016 Mar 31; 7(19). PMID: 27029062    Free PMC article.
Immunological metagene signatures derived from immunogenic cancer cell death associate with improved survival of patients with lung, breast or ovarian malignancies: A large-scale meta-analysis.
Abhishek D Garg, Dirk De Ruysscher, Patrizia Agostinis.
Oncoimmunology, 2016 Apr 09; 5(2). PMID: 27057433    Free PMC article.
Activated human mesenchymal stem/stromal cells suppress metastatic features of MDA-MB-231 cells by secreting IFN-β.
N Yoon, M S Park, +2 authors, R H Lee.
Cell Death Dis, 2016 Apr 15; 7. PMID: 27077807    Free PMC article.
Mitochondrial DNA content in breast cancer: Impact on in vitro and in vivo phenotype and patient prognosis.
Marjolein J A Weerts, Anieta M Sieuwerts, +4 authors, John W M Martens.
Oncotarget, 2016 Apr 16; 7(20). PMID: 27081694    Free PMC article.
Inference for survival prediction under the regularized Cox model.
Jennifer A Sinnott, Tianxi Cai.
Biostatistics, 2016 Apr 24; 17(4). PMID: 27107008    Free PMC article.
Neoadjuvant tamoxifen synchronizes ERα binding and gene expression profiles related to outcome and proliferation.
Tesa M Severson, Ekaterina Nevedomskaya, +14 authors, Wilbert Zwart.
Oncotarget, 2016 Apr 30; 7(23). PMID: 27129152    Free PMC article.
Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness.
Alexander Nguyen, Mitsukuni Yoshida, Hani Goodarzi, Sohail F Tavazoie.
Nat Commun, 2016 May 04; 7. PMID: 27138336    Free PMC article.
Prognostic signatures of breast cancer: Perou's molecular subtypes and Schmidt's metagenes.
Cristina Cadenas.
EXCLI J, 2012 Jan 01; 11. PMID: 27231466    Free PMC article.
The Role of the 21-Gene Recurrence Score in Breast Cancer Treatment.
Josee-Lyne Ethier, Eitan Amir.
Mol Diagn Ther, 2016 May 29; 20(4). PMID: 27235162
Review.
Breast cancer subtype predictors revisited: from consensus to concordance?
Herman M J Sontrop, Marcel J T Reinders, Perry D Moerland.
BMC Med Genomics, 2016 Jun 05; 9(1). PMID: 27259591    Free PMC article.
DNA polymerase θ (POLQ), double-strand break repair, and cancer.
Richard D Wood, Sylvie Doublié.
DNA Repair (Amst), 2016 Jun 07; 44. PMID: 27264557    Free PMC article.
Highly Cited. Review.
Bagging survival tree procedure for variable selection and prediction in the presence of nonsusceptible patients.
Cyprien Mbogning, Philippe Broët.
BMC Bioinformatics, 2016 Jun 09; 17(1). PMID: 27266372    Free PMC article.
Assessing the clinical utility of genomic expression data across human cancers.
Xinsen Xu, Lei Huang, +3 authors, Chang Liu.
Oncotarget, 2016 Jun 21; 7(29). PMID: 27322207    Free PMC article.
Meta-analytic framework for sparse K-means to identify disease subtypes in multiple transcriptomic studies.
Zhiguang Huo, Ying Ding, +2 authors, George Tseng.
J Am Stat Assoc, 2016 Jun 23; 111(513). PMID: 27330233    Free PMC article.
multiClust: An R-package for Identifying Biologically Relevant Clusters in Cancer Transcriptome Profiles.
Nathan Lawlor, Alec Fabbri, +2 authors, R Krishna Murthy Karuturi.
Cancer Inform, 2016 Jun 23; 15. PMID: 27330269    Free PMC article.
Review.
KRT19 directly interacts with β-catenin/RAC1 complex to regulate NUMB-dependent NOTCH signaling pathway and breast cancer properties.
S K Saha, H Y Choi, +5 authors, S-G Cho.
Oncogene, 2016 Jun 28; 36(3). PMID: 27345400    Free PMC article.
Detecting Pairwise Interactive Effects of Continuous Random Variables for Biomarker Identification with Small Sample Size.
Amin Ahmadi Adl, Hye-Seung Lee, Xiaoning Qian.
IEEE/ACM Trans Comput Biol Bioinform, 2016 Jul 01; 14(6). PMID: 27362985    Free PMC article.
Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer.
Zhi Hu, Jian-Hua Mao, +22 authors, Joe W Gray.
Breast Cancer Res, 2016 Jul 03; 18(1). PMID: 27368372    Free PMC article.
Analysis of phosphatases in ER-negative breast cancers identifies DUSP4 as a critical regulator of growth and invasion.
Abhijit Mazumdar, Graham M Poage, +11 authors, Powel H Brown.
Breast Cancer Res Treat, 2016 Jul 10; 158(3). PMID: 27393618    Free PMC article.
Expression profile of SIX family members correlates with clinic-pathological features and prognosis of breast cancer: A systematic review and meta-analysis.
Han-Xiao Xu, Kong-Ju Wu, +6 authors, Kong-Ming Wu.
Medicine (Baltimore), 2016 Jul 12; 95(27). PMID: 27399099    Free PMC article.
Systematic Review.
Boosting the discriminatory power of sparse survival models via optimization of the concordance index and stability selection.
Andreas Mayr, Benjamin Hofner, Matthias Schmid.
BMC Bioinformatics, 2016 Jul 23; 17. PMID: 27444890    Free PMC article.
Inhibition of Breast Cancer Metastasis by Presurgical Treatment with an Oral Matrix Metalloproteinase Inhibitor: A Preclinical Proof-of-Principle Study.
Arthur Winer, Maxwell Janosky, +7 authors, Paolo Mignatti.
Mol Cancer Ther, 2016 Jul 29; 15(10). PMID: 27466357    Free PMC article.
Identification of novel biomarkers associated with poor patient outcomes in invasive breast carcinoma.
Renata A Canevari, Fabio A Marchi, +5 authors, Eduardo M Reis.
Tumour Biol, 2016 Aug 04; 37(10). PMID: 27485113
Developmental Toxicity of Zinc Oxide Nanoparticles to Zebrafish (Danio rerio): A Transcriptomic Analysis.
Jin Soo Choi, Ryeo-Ok Kim, Seokjoo Yoon, Woo-Keun Kim.
PLoS One, 2016 Aug 10; 11(8). PMID: 27504894    Free PMC article.
Twist1 promotes breast cancer invasion and metastasis by silencing Foxa1 expression.
Y Xu, L Qin, +6 authors, J Xu.
Oncogene, 2016 Aug 16; 36(8). PMID: 27524420    Free PMC article.
ERα-XPO1 Cross Talk Controls Tamoxifen Sensitivity in Tumors by Altering ERK5 Cellular Localization.
Kinga Wrobel, Yiru Chen Zhao, +10 authors, Zeynep Madak-Erdogan.
Mol Endocrinol, 2016 Aug 18; 30(10). PMID: 27533791    Free PMC article.
Reproducible detection of disease-associated markers from gene expression data.
Katsuhiro Omae, Osamu Komori, Shinto Eguchi.
BMC Med Genomics, 2016 Aug 20; 9(1). PMID: 27538512    Free PMC article.
The 29.5 kb APOBEC3B Deletion Polymorphism Is Not Associated with Clinical Outcome of Breast Cancer.
Jingjing Liu, Anieta M Sieuwerts, +5 authors, John W M Martens.
PLoS One, 2016 Aug 24; 11(8). PMID: 27552096    Free PMC article.
Prognostic significance of nuclear expression of UMP-CMP kinase in triple negative breast cancer patients.
Ning Qing Liu, Tommaso De Marchi, +12 authors, Arzu Umar.
Sci Rep, 2016 Aug 26; 6. PMID: 27558661    Free PMC article.
Improving Pathological Assessment of Breast Cancer by Employing Array-Based Transcriptome Analysis.
Zsuzsanna Mihály, Balázs Győrffy.
Microarrays (Basel), 2013 Jan 01; 2(3). PMID: 27605190    Free PMC article.
Review.
Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model.
Leena Hilakivi-Clarke, Anni Wärri, +13 authors, Robert Clarke.
J Natl Cancer Inst, 2016 Sep 10; 109(1). PMID: 27609189    Free PMC article.
EPRS is a critical regulator of cell proliferation and estrogen signaling in ER+ breast cancer.
Igor Katsyv, Minghui Wang, +6 authors, Hanna Y Irie.
Oncotarget, 2016 Sep 11; 7(43). PMID: 27612429    Free PMC article.
Random rotation survival forest for high dimensional censored data.
Lifeng Zhou, Hong Wang, Qingsong Xu.
Springerplus, 2016 Sep 15; 5(1). PMID: 27625979    Free PMC article.
Breast cancer classification and prognostication through diverse systems along with recent emerging findings in this respect; the dawn of new perspectives in the clinical applications.
Vida Pourteimoor, Samira Mohammadi-Yeganeh, Mahdi Paryan.
Tumour Biol, 2016 Sep 22; 37(11). PMID: 27651157
Review.
Prognostic and therapeutic value of mitochondrial serine hydroxyl-methyltransferase 2 as a breast cancer biomarker.
Lahong Zhang, Zhaojun Chen, +11 authors, Yun Yen.
Oncol Rep, 2016 Oct 26; 36(5). PMID: 27666119    Free PMC article.
The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression.
Yashar S Niknafs, Sumin Han, +25 authors, Felix Y Feng.
Nat Commun, 2016 Sep 27; 7. PMID: 27666543    Free PMC article.
Highly Cited.
Blockade of the Hedgehog pathway downregulates estrogen receptor alpha signaling in breast cancer cells.
Yumei Diao, Ani Azatyan, +4 authors, Peter G Zaphiropoulos.
Oncotarget, 2016 Oct 01; 7(44). PMID: 27689403    Free PMC article.
Incorporating topological information for predicting robust cancer subnetwork markers in human protein-protein interaction network.
Navadon Khunlertgit, Byung-Jun Yoon.
BMC Bioinformatics, 2016 Oct 22; 17(Suppl 13). PMID: 27766944    Free PMC article.
Double-edged role of G protein-coupled estrogen receptor 1 in breast cancer prognosis: an analysis of 167 breast cancer samples and online data sets.
Fan Yang, Zhi-Min Shao.
Onco Targets Ther, 2016 Nov 09; 9. PMID: 27822058    Free PMC article.
MinePath: Mining for Phenotype Differential Sub-paths in Molecular Pathways.
Lefteris Koumakis, Alexandros Kanterakis, +8 authors, George Potamias.
PLoS Comput Biol, 2016 Nov 11; 12(11). PMID: 27832067    Free PMC article.
Immunoglobulin superfamily genes are novel prognostic biomarkers for breast cancer.
Yue Li, Maoni Guo, +6 authors, Dianjun Li.
Oncotarget, 2016 Dec 03; 8(2). PMID: 27911271    Free PMC article.
Epsin Family Member 3 and Ribosome-Related Genes Are Associated with Late Metastasis in Estrogen Receptor-Positive Breast Cancer and Long-Term Survival in Non-Small Cell Lung Cancer Using a Genome-Wide Identification and Validation Strategy.
Birte Hellwig, Katrin Madjar, +11 authors, Jörg Rahnenführer.
PLoS One, 2016 Dec 08; 11(12). PMID: 27926932    Free PMC article.
c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun.
X Xie, T S Kaoud, +12 authors, N T Ueno.
Oncogene, 2016 Dec 13; 36(18). PMID: 27941886    Free PMC article.
Inherent variability of cancer-specific aneuploidy generates metastases.
Mathew Bloomfield, Peter Duesberg.
Mol Cytogenet, 2016 Dec 27; 9. PMID: 28018487    Free PMC article.
Pathway-Structured Predictive Model for Cancer Survival Prediction: A Two-Stage Approach.
Xinyan Zhang, Yan Li, +5 authors, Nengjun Yi.
Genetics, 2017 Jan 05; 205(1). PMID: 28049703    Free PMC article.
A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer.
Bogdan-Tiberius Preca, Karolina Bajdak, +9 authors, Marc P Stemmler.
Oncotarget, 2017 Jan 14; 8(7). PMID: 28086235    Free PMC article.
Contextual Refinement of Regulatory Targets Reveals Effects on Breast Cancer Prognosis of the Regulome.
Erik Andrews, Yue Wang, +2 authors, Chao Cheng.
PLoS Comput Biol, 2017 Jan 20; 13(1). PMID: 28103241    Free PMC article.
EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth.
Naiara Perurena, Carolina Zandueta, +9 authors, Fernando Lecanda.
J Hematol Oncol, 2017 Jan 21; 10(1). PMID: 28103946    Free PMC article.
Genome-wide screen identifies a novel prognostic signature for breast cancer survival.
Xuan Y Mao, Matthew J Lee, +3 authors, Antoine M Snijders.
Oncotarget, 2017 Jan 26; 8(8). PMID: 28122328    Free PMC article.
A Systematic Framework for Drug Repositioning from Integrated Omics and Drug Phenotype Profiles Using Pathway-Drug Network.
Erkhembayar Jadamba, Miyoung Shin.
Biomed Res Int, 2017 Jan 28; 2016. PMID: 28127549    Free PMC article.
Consistent metagenomic biomarker detection via robust PCA.
Mustafa Alshawaqfeh, Ahmad Bashaireh, Erchin Serpedin, Jan Suchodolski.
Biol Direct, 2017 Feb 02; 12(1). PMID: 28143486    Free PMC article.
Metalloprotease-disintegrin ADAM12 actively promotes the stem cell-like phenotype in claudin-low breast cancer.
Sara Duhachek-Muggy, Yue Qi, +4 authors, Anna Zolkiewska.
Mol Cancer, 2017 Feb 06; 16(1). PMID: 28148288    Free PMC article.
Simultaneous identification of robust synergistic subnetwork markers for effective cancer prognosis.
Navadon Khunlertgit, Byung-Jun Yoon.
EURASIP J Bioinform Syst Biol, 2014 Nov 06; 2014. PMID: 28194169    Free PMC article.
Transcriptomic dynamics of breast cancer progression in the MMTV-PyMT mouse model.
Ying Cai, Ruben Nogales-Cadenas, +5 authors, Zhengdong D Zhang.
BMC Genomics, 2017 Feb 19; 18(1). PMID: 28212608    Free PMC article.
Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification.
Liming Chen, Piroon Jenjaroenpun, +15 authors, Jean Paul Thiery.
Proc Natl Acad Sci U S A, 2017 Mar 03; 114(11). PMID: 28251929    Free PMC article.
Personalized chemotherapy selection for breast cancer using gene expression profiles.
Kaixian Yu, Qing-Xiang Amy Sang, +6 authors, Jinfeng Zhang.
Sci Rep, 2017 Mar 04; 7. PMID: 28256629    Free PMC article.
DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms.
David J Lemler, Miranda L Lynch, +7 authors, Frank M Torti.
Breast Cancer Res, 2017 Mar 09; 19(1). PMID: 28270217    Free PMC article.
Sphingosylphosphorylcholine Induces Thrombospondin-1 Secretion in MCF10A Cells via ERK2.
June Hee Kang, Hyun Ji Kim, Mi Kyung Park, Chang Hoon Lee.
Biomol Ther (Seoul), 2017 Mar 10; 25(6). PMID: 28274095    Free PMC article.
Distance in cancer gene expression from stem cells predicts patient survival.
Markus Riester, Hua-Jun Wu, +4 authors, Franziska Michor.
PLoS One, 2017 Mar 24; 12(3). PMID: 28333954    Free PMC article.
Molecular Subtyping of Pancreatic Cancer: Translating Genomics and Transcriptomics into the Clinic.
Yongxing Du, Bangbo Zhao, +5 authors, Yupei Zhao.
J Cancer, 2017 Apr 04; 8(4). PMID: 28367231    Free PMC article.
Review.
A 3q gene signature associated with triple negative breast cancer organ specific metastasis and response to neoadjuvant chemotherapy.
Jun Qian, Heidi Chen, +4 authors, Pierre P Massion.
Sci Rep, 2017 Apr 08; 7. PMID: 28387221    Free PMC article.
Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer.
Tristan Gallenne, Kenneth N Ross, +6 authors, Daniel S Peeper.
Oncotarget, 2017 Apr 16; 8(13). PMID: 28411283    Free PMC article.
The prognostic significance of Cdc6 and Cdt1 in breast cancer.
Ravikiran Mahadevappa, Henrique Neves, +6 authors, Hang Fai Kwok.
Sci Rep, 2017 Apr 22; 7(1). PMID: 28428557    Free PMC article.
Disease biomarker identification from gene network modules for metastasized breast cancer.
Pooja Sharma, Dhruba K Bhattacharyya, Jugal Kalita.
Sci Rep, 2017 Apr 23; 7(1). PMID: 28432361    Free PMC article.
Increased risk of brain metastases in women with breast cancer and p16 expression in metastatic lymph-nodes.
Elise Furet, Morad El Bouchtaoui, +8 authors, Guilhem Bousquet.
Oncotarget, 2017 Apr 27; 8(23). PMID: 28445153    Free PMC article.
The E2F4 prognostic signature predicts pathological response to neoadjuvant chemotherapy in breast cancer patients.
Kenneth M K Mark, Frederick S Varn, +2 authors, Chao Cheng.
BMC Cancer, 2017 May 04; 17(1). PMID: 28464832    Free PMC article.
ADAM12 induction by Twist1 promotes tumor invasion and metastasis via regulation of invadopodia and focal adhesions.
Mark A Eckert, Miguel Santiago-Medina, +3 authors, Jing Yang.
J Cell Sci, 2017 May 05; 130(12). PMID: 28468988    Free PMC article.
Node-Structured Integrative Gaussian Graphical Model Guided by Pathway Information.
SungHwan Kim, Jae-Hwan Jhong, +3 authors, SungWon Han.
Comput Math Methods Med, 2017 May 11; 2017. PMID: 28487748    Free PMC article.
Identification of breast cancer prognostic modules based on weighted protein-protein interaction networks.
Wan Li, Xue Bai, +6 authors, Weiming He.
Oncol Lett, 2017 May 23; 13(5). PMID: 28529601    Free PMC article.
In vitro downregulated hypoxia transcriptome is associated with poor prognosis in breast cancer.
Basel Abu-Jamous, Francesca M Buffa, Adrian L Harris, Asoke K Nandi.
Mol Cancer, 2017 Jun 18; 16(1). PMID: 28619028    Free PMC article.
Quasi-linear score for capturing heterogeneous structure in biomarkers.
Katsuhiro Omae, Osamu Komori, Shinto Eguchi.
BMC Bioinformatics, 2017 Jun 21; 18(1). PMID: 28629325    Free PMC article.
Early response index: a statistic to discover potential early stage disease biomarkers.
Sirajul Salekin, Mehrab Ghanat Bari, +2 authors, Jianqiu Michelle Zhang.
BMC Bioinformatics, 2017 Jun 25; 18(1). PMID: 28645323    Free PMC article.
DACH1 suppresses breast cancer as a negative regulator of CD44.
Hanxiao Xu, Shengnan Yu, +4 authors, Kongming Wu.
Sci Rep, 2017 Jul 01; 7(1). PMID: 28659634    Free PMC article.
Glycosylation of KEAP1 links nutrient sensing to redox stress signaling.
Po-Han Chen, Timothy J Smith, +11 authors, Jen-Tsan Chi.
EMBO J, 2017 Jul 01; 36(15). PMID: 28663241    Free PMC article.
Loss of constitutive ABCB1 expression in breast cancer associated with worse prognosis.
João Marcos de Azevedo Delou, Giselle Maria Vignal, +7 authors, Rosane Vianna-Jorge.
Breast Cancer (Dove Med Press), 2017 Jul 04; 9. PMID: 28670140    Free PMC article.
Prognostic cancer gene signatures share common regulatory motifs.
Ying Wang, Steve Goodison, Xiaoman Li, Haiyan Hu.
Sci Rep, 2017 Jul 08; 7(1). PMID: 28684851    Free PMC article.
Molecular genetics complexity impeding research progress in breast and ovarian cancers.
Ishita Gupta, Ikram Burney, Mansour S Al-Moundhri, Yahya Tamimi.
Mol Clin Oncol, 2017 Jul 08; 7(1). PMID: 28685067    Free PMC article.
Overexpression of Uridine-Cytidine Kinase 2 Correlates with Breast Cancer Progression and Poor Prognosis.
Guosong Shen, Pingya He, +5 authors, Yun Yen.
J Breast Cancer, 2017 Jul 12; 20(2). PMID: 28690649    Free PMC article.
Reliable Biomarker discovery from Metagenomic data via RegLRSD algorithm.
Mustafa Alshawaqfeh, Ahmad Bashaireh, Erchin Serpedin, Jan Suchodolski.
BMC Bioinformatics, 2017 Jul 12; 18(1). PMID: 28693478    Free PMC article.
Evolutionary Origins of Cancer Driver Genes and Implications for Cancer Prognosis.
Xin-Yi Chu, Ling-Han Jiang, +2 authors, Hong-Yu Zhang.
Genes (Basel), 2017 Jul 15; 8(7). PMID: 28708071    Free PMC article.
Widespread alternative exon usage in clinically distinct subtypes of Invasive Ductal Carcinoma.
Sunniva Stordal Bjørklund, Anshuman Panda, +12 authors, Gyan Bhanot.
Sci Rep, 2017 Jul 19; 7(1). PMID: 28717182    Free PMC article.
Identifying biological mechanisms for favorable cancer prognosis using non-hypothesis-driven iterative survival analysis.
Isaac Crespo, Lou Götz, +3 authors, Ioannis Xenarios.
NPJ Syst Biol Appl, 2017 Jul 21; 2. PMID: 28725481    Free PMC article.
Data integration with high dimensionality.
Xin Gao, Raymond J Carroll.
Biometrika, 2017 Aug 02; 104(2). PMID: 28757650    Free PMC article.
A novel FOXA1/ESR1 interacting pathway: A study of Oncomine™ breast cancer microarrays.
Sanjib Chaudhary, B Madhu Krishna, Sandip K Mishra.
Oncol Lett, 2017 Aug 10; 14(2). PMID: 28789340    Free PMC article.
Identification of Nidogen 1 as a lung metastasis protein through secretome analysis.
Maša Alečković, Yong Wei, +4 authors, Yibin Kang.
Genes Dev, 2017 Aug 23; 31(14). PMID: 28827399    Free PMC article.
Tumour radiosensitivity is associated with immune activation in solid tumours.
Tobin Strom, Louis B Harrison, +11 authors, Javier F Torres-Roca.
Eur J Cancer, 2017 Sep 02; 84. PMID: 28863385    Free PMC article.
SPEN, a new player in primary cilia formation and cell migration in breast cancer.
Stéphanie Légaré, Catherine Chabot, Mark Basik.
Breast Cancer Res, 2017 Sep 08; 19(1). PMID: 28877752    Free PMC article.
The landscape of DNA methylation-mediated regulation of long non-coding RNAs in breast cancer.
Chunlong Zhang, Xinyu Wang, +7 authors, Yan Zhang.
Oncotarget, 2017 Sep 09; 8(31). PMID: 28881636    Free PMC article.
Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer.
Skye Hung-Chun Cheng, Tzu-Ting Huang, +6 authors, Ben-Long Yu.
PLoS One, 2017 Sep 09; 12(9). PMID: 28886126    Free PMC article.
The Eya phosphatase: Its unique role in cancer.
Hengbo Zhou, Lingdi Zhang, +2 authors, Rui Zhao.
Int J Biochem Cell Biol, 2017 Sep 10; 96. PMID: 28887153    Free PMC article.
Review.
G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer.
Christina Y Yim, Emmanuel Bikorimana, +6 authors, Michael J Spinella.
Cell Cycle, 2017 Sep 15; 16(21). PMID: 28910567    Free PMC article.
MicroRNA-154 inhibits the growth and metastasis of gastric cancer cells by directly targeting MTDH.
Wenhui Qiao, Nong Cao, Lei Yang.
Oncol Lett, 2017 Sep 21; 14(3). PMID: 28927076    Free PMC article.
Pathway Enrichment Analysis with Networks.
Lu Liu, Jinmao Wei, Jianhua Ruan.
Genes (Basel), 2017 Sep 29; 8(10). PMID: 28956817    Free PMC article.
CytoGTA: A cytoscape plugin for identifying discriminative subnetwork markers using a game theoretic approach.
S Farahmand, M H Foroughmand-Araabi, S Goliaei, Z Razaghi-Moghadam.
PLoS One, 2017 Oct 03; 12(10). PMID: 28968407    Free PMC article.
Genome-wide identification of key modulators of gene-gene interaction networks in breast cancer.
Yu-Chiao Chiu, Li-Ju Wang, +2 authors, Yidong Chen.
BMC Genomics, 2017 Oct 07; 18(Suppl 6). PMID: 28984209    Free PMC article.
TGF-β1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up-regulation of IL-17RB.
Shih-Chia Huang, Pei-Chi Wei, +8 authors, Wen-Hwa Lee.
EMBO Mol Med, 2017 Oct 11; 9(12). PMID: 28993429    Free PMC article.
Prognostic genes of breast cancer revealed by gene co-expression network analysis.
Huijie Shi, Lei Zhang, +3 authors, Min Zheng.
Oncol Lett, 2017 Nov 01; 14(4). PMID: 29085450    Free PMC article.
Protective role of LRRC3B in preventing breast cancer metastasis and recurrence post-bupivacaine.
Gong-Sheng Li, Gao-Yin Kong, Yi Zou.
Oncol Lett, 2017 Nov 01; 14(4). PMID: 29085514    Free PMC article.
Clinical utility of multigene profiling assays in early-stage breast cancer.
M C Chang, L H Souter, +6 authors, Molecular Oncology Advisory Committee.
Curr Oncol, 2017 Nov 02; 24(5). PMID: 29089811    Free PMC article.
Gene network inherent in genomic big data improves the accuracy of prognostic prediction for cancer patients.
Yun Hak Kim, Dae Cheon Jeong, +9 authors, Sae-Ock Oh.
Oncotarget, 2017 Nov 05; 8(44). PMID: 29100405    Free PMC article.
Computational Investigation of Homologous Recombination DNA Repair Deficiency in Sporadic Breast Cancer.
Yue Wang, Matthew H Ung, Sharon Cantor, Chao Cheng.
Sci Rep, 2017 Nov 18; 7(1). PMID: 29146938    Free PMC article.
A transcriptomic insight into the impacts of mast cells in lung, breast, and colon cancers.
Eun-A Ko, Kenton M Sanders, Tong Zhou.
Oncoimmunology, 2017 Nov 18; 6(11). PMID: 29147625    Free PMC article.
A 16-gene signature predicting prognosis of patients with oral tongue squamous cell carcinoma.
Zeting Qiu, Wei Sun, +4 authors, Wenqi Huang.
PeerJ, 2017 Nov 22; 5. PMID: 29158988    Free PMC article.
Prostate Cancer Imaging and Biomarkers Guiding Safe Selection of Active Surveillance.
Zachary A Glaser, Jennifer B Gordetsky, +2 authors, Soroush Rais-Bahrami.
Front Oncol, 2017 Nov 23; 7. PMID: 29164056    Free PMC article.
Review.
PTK6 regulates growth and survival of endocrine therapy-resistant ER+ breast cancer cells.
Koichi Ito, Sun Hee Park, +4 authors, Hanna Y Irie.
NPJ Breast Cancer, 2017 Nov 24; 3. PMID: 29167821    Free PMC article.
Robust method for identification of prognostic gene signatures from gene expression profiles.
Woogwang Sim, Jungsul Lee, Chulhee Choi.
Sci Rep, 2017 Dec 07; 7(1). PMID: 29208919    Free PMC article.
The Role of micro RNAs in Breast Cancer Metastasis: Preclinical Validation and Potential Therapeutic Targets.
Ulrich H Weidle, Steffen Dickopf, +3 authors, Ulrich Brinkmann.
Cancer Genomics Proteomics, 2017 Dec 25; 15(1). PMID: 29275360    Free PMC article.
Review.
Identification of prognostic signature in cancer based on DNA methylation interaction network.
Wei-Lin Hu, Xiong-Hui Zhou.
BMC Med Genomics, 2018 Jan 13; 10(Suppl 4). PMID: 29322932    Free PMC article.
IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer.
Yinghui Zhang, Lynn Wester, +15 authors, Bob van de Water.
Oncogene, 2018 Jan 23; 37(14). PMID: 29353882
CD44/CD24 and aldehyde dehydrogenase 1 in estrogen receptor-positive early breast cancer treated with tamoxifen: CD24 positivity is a poor prognosticator.
Yong Wha Moon, Hee-Jung An, +11 authors, Joohyuk Sohn.
Oncotarget, 2018 Feb 09; 9(2). PMID: 29416796    Free PMC article.
Evolutionary history of metastatic breast cancer reveals minimal seeding from axillary lymph nodes.
Ikram Ullah, Govindasamy-Muralidharan Karthik, +8 authors, Jonas Bergh.
J Clin Invest, 2018 Feb 27; 128(4). PMID: 29480816    Free PMC article.
Highly Cited.
A collection of annotated and harmonized human breast cancer transcriptome datasets, including immunologic classification.
Jessica Roelands, Julie Decock, +19 authors, Wouter Hendrickx.
F1000Res, 2018 Mar 15; 6. PMID: 29527288    Free PMC article.
Investigating a multigene prognostic assay based on significant pathways for Luminal A breast cancer through gene expression profile analysis.
Haiyan Gao, Mei Yang, Xiaolan Zhang.
Oncol Lett, 2018 Mar 17; 15(4). PMID: 29545900    Free PMC article.
Modulation of Molecular Biomarker Expression in Response to Chemotherapy in Invasive Ductal Carcinoma.
Mana Oloomi, Neda Moazzezy, Saeid Bouzari.
Biomed Res Int, 2018 Apr 06; 2018. PMID: 29619374    Free PMC article.
Pathway aggregation for survival prediction via multiple kernel learning.
Jennifer A Sinnott, Tianxi Cai.
Stat Med, 2018 Apr 18; 37(16). PMID: 29664143    Free PMC article.
Identifying statistically significant combinatorial markers for survival analysis.
Raissa T Relator, Aika Terada, Jun Sese.
BMC Med Genomics, 201