Journal Article
. 2006 May; 24(19):3187-205.
doi: 10.1200/JCO.2006.06.4451.

2006 update of recommendations for the use of white blood cell growth factors: an evidence-based clinical practice guideline

Thomas J Smith 1 James Khatcheressian  Gary H Lyman  Howard Ozer  James O Armitage  Lodovico Balducci  Charles L Bennett  Scott B Cantor  Jeffrey Crawford  Scott J Cross  George Demetri  Christopher E Desch  Philip A Pizzo  Charles A Schiffer  Lee Schwartzberg  Mark R Somerfield  George Somlo  James C Wade  James L Wade  Rodger J Winn  Antoinette J Wozniak  Antonio C Wolff  
  • PMID: 16682719
  •     411 citations


Purpose: To update the 2000 American Society of Clinical Oncology guideline on the use of hematopoietic colony-stimulating factors (CSF).

Update Methodology: The Update Committee completed a review and analysis of pertinent data published from 1999 through September 2005. Guided by the 1996 ASCO clinical outcomes criteria, the Update Committee formulated recommendations based on improvements in survival, quality of life, toxicity reduction and cost-effectiveness.

Recommendations: The 2005 Update Committee agreed unanimously that reduction in febrile neutropenia (FN) is an important clinical outcome that justifies the use of CSFs, regardless of impact on other factors, when the risk of FN is approximately 20% and no other equally effective regimen that does not require CSFs is available. Primary prophylaxis is recommended for the prevention of FN in patients who are at high risk based on age, medical history, disease characteristics, and myelotoxicity of the chemotherapy regimen. CSF use allows a modest to moderate increase in dose-density and/or dose-intensity of chemotherapy regimens. Dose-dense regimens should only be used within an appropriately designed clinical trial or if supported by convincing efficacy data. Prophylactic CSF for patients with diffuse aggressive lymphoma aged 65 years and older treated with curative chemotherapy (CHOP or more aggressive regimens) should be given to reduce the incidence of FN and infections. Current recommendations for the management of patients exposed to lethal doses of total body radiotherapy, but not doses high enough to lead to certain death due to injury to other organs, includes the prompt administration of CSF or pegylated G-CSF.

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The cost-utility of adjuvant chemotherapy using docetaxel and cyclophosphamide compared with doxorubicin and cyclophosphamide in breast cancer.
T Younis, D Rayson, C Skedgel.
Curr Oncol, 2011 Dec 21; 18(6). PMID: 22184496    Free PMC article.
Colony stimulating factors (CSF) biosimilars. Progress?
Florian Scotté, Vincent Launay-Vacher, Jean-Baptiste Rey.
Target Oncol, 2012 Jan 18; 7 Suppl 1. PMID: 22249656
Primary G-CSF prophylaxis for adjuvant TC or FEC-D chemotherapy outside of clinical trial settings: a systematic review and meta-analysis.
Tallal Younis, Daniel Rayson, Kara Thompson.
Support Care Cancer, 2012 Jan 19; 20(10). PMID: 22252548
Systematic Review.
Feasibility Of Administering Adjuvant Chemotherapy Of Pemetrexed Followed By Pemetrexed/oxaliplatin Immediately Post-VATS In Patients With Completely Resected NSCLC.
Jianxing He, Wenlong Shao, +6 authors, Daoyuan Wang.
J Thorac Dis, 2009 Dec 01; 1(1). PMID: 22263005    Free PMC article.
Uptake and economic impact of first-cycle colony-stimulating factor use during adjuvant treatment of breast cancer.
Dawn L Hershman, Elizabeth T Wilde, +4 authors, Alfred I Neugut.
J Clin Oncol, 2012 Feb 09; 30(8). PMID: 22312106    Free PMC article.
Acute radiation syndrome (ARS) - treatment of the reduced host defense.
Lars Heslet, Christiane Bay, Steen Nepper-Christensen.
Int J Gen Med, 2012 Feb 10; 5. PMID: 22319248    Free PMC article.
A way forward on the medically appropriate use of white cell growth factors.
Thomas J Smith, Bruce E Hillner.
J Clin Oncol, 2012 Mar 01; 30(14). PMID: 22370327    Free PMC article.
Skin and soft tissue infections in patients with solid tumours.
Diamantis P Kofteridis, Antonios Valachis, +7 authors, George Samonis.
ScientificWorldJournal, 2012 Mar 27; 2012. PMID: 22448140    Free PMC article.
[Myelopoiesis and bone marrow function in elderly tumor patients].
G F Kolb.
Z Gerontol Geriatr, 2012 Mar 28; 45(3). PMID: 22451304
Randomized, double-blind, placebo-controlled phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic castration-resistant prostate cancer: CALGB 90401.
William Kevin Kelly, Susan Halabi, +9 authors, Eric J Small.
J Clin Oncol, 2012 Mar 29; 30(13). PMID: 22454414    Free PMC article.
Highly Cited.
Hematopoietic growth factors: personalization of risks and benefits.
Shannon Puhalla, Saveri Bhattacharya, Nancy E Davidson.
Mol Oncol, 2012 Apr 14; 6(2). PMID: 22497867    Free PMC article.
Induction of Bv8 expression by granulocyte colony-stimulating factor in CD11b+Gr1+ cells: key role of Stat3 signaling.
Xueping Qu, Guanglei Zhuang, +2 authors, Napoleone Ferrara.
J Biol Chem, 2012 Apr 25; 287(23). PMID: 22528488    Free PMC article.
Pharmacoeconomics of the myeloid growth factors: a critical and systematic review.
Bradford R Hirsch, Gary H Lyman.
Pharmacoeconomics, 2012 May 01; 30(6). PMID: 22540394
Systematic Review.
A randomised trial of granulocyte-macrophage colony-stimulating factor for neonatal sepsis: outcomes at 2 years.
Neil Marlow, Timothy Morris, +7 authors, Caroline Dore.
Arch Dis Child Fetal Neonatal Ed, 2012 May 01; 98(1). PMID: 22542709    Free PMC article.
Filgrastim as a rescue therapy for persistent neutropenia in a case of dengue hemorrhagic Fever with acute respiratory distress syndrome and myocarditis.
Desh Deepak, Rakesh Garg, +3 authors, Indubala Maurya.
Case Rep Anesthesiol, 2011 Jan 01; 2011. PMID: 22606398    Free PMC article.
Incidence of febrile neutropenia during adjuvant chemotherapy for breast cancer: a prospective study.
D Rayson, S Lutes, +6 authors, T Younis.
Curr Oncol, 2012 Jun 07; 19(3). PMID: 22670112    Free PMC article.
The critically-ill pediatric hemato-oncology patient: epidemiology, management, and strategy of transfer to the pediatric intensive care unit.
Pierre Demaret, Geraldine Pettersen, +2 authors, Guillaume Emeriaud.
Ann Intensive Care, 2012 Jun 14; 2(1). PMID: 22691690    Free PMC article.
Austrian Arbeitsgemeinschaft für Gynäkologische Onkologie (AGO) guideline for prophylaxis with granulocyte colony-stimulating factors (G-CSF) in gynecologic malignancies, including breast cancer.
Edgar Petru, Alain Gustave Zeimet, +9 authors, Austrian Arbeitsgemeinschaft für Gynäkologische Onkologie (AGO).
Wien Klin Wochenschr, 2012 Jun 29; 124(11-12). PMID: 22739650
Prediction of docetaxel monotherapy-induced neutropenia based on the monocyte percentage.
Itaru Sato, Naoki Nakaya, +2 authors, Yoshiharu Motoo.
Oncol Lett, 2012 Jun 29; 3(4). PMID: 22741007    Free PMC article.
Splenectomy revisited in 2011: Impact on hematologic toxicities while performing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
Nancy Deslauriers, Harold Olney, Rami Younan.
J Gastrointest Oncol, 2012 Jul 20; 2(2). PMID: 22811831    Free PMC article.
Personalising docetaxel and G-CSF schedules in cancer patients by a clinically validated computational model.
O Vainas, S Ariad, +8 authors, Z Agur.
Br J Cancer, 2012 Jul 21; 107(5). PMID: 22814580    Free PMC article.
Use and delivery of granulocyte colony-stimulating factor in breast cancer patients receiving neoadjuvant or adjuvant chemotherapy-single-centre experience.
X Zhu, N Bouganim, +3 authors, M J Clemons.
Curr Oncol, 2012 Aug 10; 19(4). PMID: 22876152    Free PMC article.
Treatment-related death in patients with small-cell lung cancer in phase III trials over the last two decades.
Nobuaki Ochi, Katsuyuki Hotta, +7 authors, Katsuyuki Kiura.
PLoS One, 2012 Aug 11; 7(8). PMID: 22880112    Free PMC article.
Economic costs of chemotherapy-induced febrile neutropenia among patients with non-Hodgkin's lymphoma in European and Australian clinical practice.
Derek Weycker, Aurelie Danel, +3 authors, Ruth Pettengell.
BMC Cancer, 2012 Aug 24; 12. PMID: 22913768    Free PMC article.
A nonhuman primate model of the hematopoietic acute radiation syndrome plus medical management.
Ann M Farese, Melanie V Cohen, +4 authors, Thomas J MacVittie.
Health Phys, 2012 Aug 30; 103(4). PMID: 22929469    Free PMC article.
Guideline-Based Peer-to-Peer Consultation Optimizes Pegfilgrastim Use With No Adverse Clinical Consequences.
Marc L Fishman, Akhil Kumar, +2 authors, William J M Hrushesky.
J Oncol Pract, 2012 Sep 04; 8(3 Suppl). PMID: 22942828    Free PMC article.
Primary prophylaxis with granulocyte colony-stimulating factor (GCSF) reduces the incidence of febrile neutropenia in patients with non-Hodgkin lymphoma (NHL) receiving CHOP chemotherapy treatment without adversely affecting their quality of life: cost-benefit and quality of life analysis.
Sophie Lee, Angela Knox, +3 authors, Samar Issa.
Support Care Cancer, 2012 Sep 14; 21(3). PMID: 22972488
Costs and outcomes associated with hospitalized cancer patients with neutropenic complications: A retrospective study.
M Blane Schilling, Connie Parks, Robert G Deeter.
Exp Ther Med, 2012 Sep 15; 2(5). PMID: 22977589    Free PMC article.
Predictors of response of patients with solid tumors to granulocyte colony-stimulating factor.
Hiroaki Ohnaka, Hitoshi Tsukamoto, +5 authors, Mikio Masada.
Int J Clin Pharm, 2012 Sep 27; 35(1). PMID: 23011270
The importance of supportive care in optimizing treatment outcomes of patients with advanced prostate cancer.
Florian Scotté.
Oncologist, 2012 Oct 04; 17 Suppl 1. PMID: 23015682    Free PMC article.
The experience with cytotoxic chemotherapy in metastatic castration-resistant prostate cancer.
Mario A Eisenberger, Emmanuel S Antonarakis.
Urol Clin North Am, 2012 Oct 23; 39(4). PMID: 23084532    Free PMC article.
Chemotherapy-Induced Neutropenia in HIV Positive Patients with Lymphoma: Comparison of Pegfilgrastim with Daily Filgrastim Administration.
Luciana Teofili, Immacolata Izzi, +4 authors, Katleen de Gaetano Donati.
Mediterr J Hematol Infect Dis, 2012 Nov 22; 4(1). PMID: 23170191    Free PMC article.
Febrile neutropenia: outline of management.
Sapna Oberoi, Renu Suthar, Deepak Bansal, R K Marwaha.
Indian J Pediatr, 2012 Nov 28; 80(2). PMID: 23180404
Filgrastim improves survival in lethally irradiated nonhuman primates.
Ann M Farese, Melanie V Cohen, +4 authors, Thomas J MacVittie.
Radiat Res, 2012 Dec 06; 179(1). PMID: 23210705    Free PMC article.
68-year-old man with neutropenic fever and upper extremity hematoma.
Elena Beam, Aaron S Mansfield, Carrie A Thompson.
Mayo Clin Proc, 2012 Dec 12; 87(12). PMID: 23218088    Free PMC article.
Retinoid agonist Am80-enhanced neutrophil bactericidal activity arising from granulopoiesis in vitro and in a neutropenic mouse model.
Wanjing Ding, Hiroyuki Shimada, +6 authors, Lingtao Wu.
Blood, 2012 Dec 18; 121(6). PMID: 23243275    Free PMC article.
Phase II study of lenalidomide and rituximab as salvage therapy for patients with relapsed or refractory chronic lymphocytic leukemia.
Xavier C Badoux, Michael J Keating, +6 authors, Alessandra Ferrajoli.
J Clin Oncol, 2012 Dec 28; 31(5). PMID: 23270003    Free PMC article.
Pegfilgrastim prophylaxis is associated with a lower risk of hospitalization of cancer patients than filgrastim prophylaxis: a retrospective United States claims analysis of granulocyte colony-stimulating factors (G-CSF).
Arash Naeim, Henry J Henk, +4 authors, Robert Deeter.
BMC Cancer, 2013 Jan 10; 13. PMID: 23298389    Free PMC article.
Febrile neutropenia rates with adjuvant docetaxel and cyclophosphamide chemotherapy in early breast cancer: discrepancy between published reports and community practice-an updated analysis.
J Younus, T Vandenberg, M Jawaid, M A Jawaid.
Curr Oncol, 2013 Jan 10; 19(6). PMID: 23300360    Free PMC article.
A randomized, non-inferiority study comparing efficacy and safety of a single dose of pegfilgrastim versus daily filgrastim in pediatric patients after autologous peripheral blood stem cell transplant.
Simone Cesaro, Francesca Nesi, +4 authors, Elisabetta Calore.
PLoS One, 2013 Jan 12; 8(1). PMID: 23308174    Free PMC article.
Mobilization of PBSC for allogeneic transplantation by the use of the G-CSF biosimilar XM02 in healthy donors.
M Schmitt, X Xu, +5 authors, A Schmitt.
Bone Marrow Transplant, 2013 Jan 16; 48(7). PMID: 23318540    Free PMC article.
Supportive therapy in medical therapy of head and neck tumors.
Hartmut Link.
GMS Curr Top Otorhinolaryngol Head Neck Surg, 2013 Jan 16; 11. PMID: 23320053    Free PMC article.
Neutropenia and G-CSF in lymphoproliferative diseases.
Roberto Ria, Antonia Reale, +2 authors, Angelo Vacca.
Hematology, 2013 Jan 17; 18(3). PMID: 23321273    Free PMC article.
Analysis of chemotherapy-induced neutropenia and optimal timing for prophylactic use of G-CSF in B-cell non-Hodgkin lymphoma patients treated with R-CHOP.
Hisaharu Shikata, Yoshihiro Yakushijin, +2 authors, Masaki Yasukawa.
Int J Clin Oncol, 2013 Feb 06; 19(1). PMID: 23380958
Technical evaluation of methods for identifying chemotherapy-induced febrile neutropenia in healthcare claims databases.
Derek Weycker, Oleg Sofrygin, +3 authors, John Edelsberg.
BMC Health Serv Res, 2013 Feb 15; 13. PMID: 23406481    Free PMC article.
Primary prophylaxis of bacterial infections and Pneumocystis jirovecii pneumonia in patients with hematological malignancies and solid tumors : guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO).
S Neumann, S W Krause, +4 authors, German Society of Hematology and Oncology (DGHO).
Ann Hematol, 2013 Feb 16; 92(4). PMID: 23412562    Free PMC article.
Deviations from guideline-based therapy for febrile neutropenia in cancer patients and their effect on outcomes.
Jason D Wright, Alfred I Neugut, +5 authors, Dawn L Hershman.
JAMA Intern Med, 2013 Mar 06; 173(7). PMID: 23460379    Free PMC article.
Breakthrough febrile neutropenia and associated complications among elderly cancer patients receiving myelosuppressive chemotherapy for solid tumors and lymphomas.
Alexandre Chan, Chee Ping Lee, Joen Chiang, Raymond Ng.
Support Care Cancer, 2013 Mar 09; 21(8). PMID: 23471537
Colony-stimulating factors for febrile neutropenia during cancer therapy.
Charles L Bennett, Benjamin Djulbegovic, LeAnn B Norris, James O Armitage.
N Engl J Med, 2013 Mar 22; 368(12). PMID: 23514290    Free PMC article.
The MASCC Neutropenia, Infection and Myelosuppression Study Group evaluates recent new concepts for the use of granulocyte colony-stimulating factors for the prevention of febrile neutropenia.
Jean Klastersky, Harry Raftopoulos, Bernardo Rapoport.
Support Care Cancer, 2013 Mar 26; 21(6). PMID: 23525960
Immunomodulation Therapy for Invasive Aspergillosis: Discussion on Myeloid Growth Factors, Recombinant Cytokines, and Antifungal Drug Immune Modulation.
Amar Safdar.
Curr Fungal Infect Rep, 2010 Mar 01; 4(1). PMID: 23585915
Pseudomonas aeruginosa endocarditis in acute myeloid leukemia: a rare complication.
Barshay J, Nemets A, Ducach A, Lugassy G.
Int J Biomed Sci, 2008 Dec 01; 4(4). PMID: 23675106    Free PMC article.
A randomized, multi-center, open-label, phase II study of once-per-cycle DA-3031, a biosimilar pegylated G-CSF, compared with daily filgrastim in patients receiving TAC chemotherapy for early-stage breast cancer.
K H Park, J H Sohn, +12 authors, J H Seo.
Invest New Drugs, 2013 May 17; 31(5). PMID: 23677653
Optimal management of patients receiving cabazitaxel-based chemotherapy.
Catherine Sperlich, Fred Saad.
Can Urol Assoc J, 2013 May 18; 7(1-2 Suppl 1). PMID: 23682302    Free PMC article.
Pharmaceutical follow-up for patients on rituximab therapy for non-Hodgkin lymphoma: what is the evidence?
Vanessa Hegele, Paula Stoll, +4 authors, Luciane Pereira Lindenmeyer.
Int J Clin Pharm, 2013 Jun 06; 35(4). PMID: 23737385
Systematic Review.
Real-world impact of granulocyte-colony stimulating factor on febrile neutropenia.
A K Altwairgi, W M Hopman, M Mates.
Curr Oncol, 2013 Jun 06; 20(3). PMID: 23737687    Free PMC article.
Incidence and predictors of febrile neutropenia during chemotherapy in patients with head and neck cancer.
Yukinori Takenaka, Hironori Cho, +3 authors, Hidenori Inohara.
Support Care Cancer, 2013 Jun 12; 21(10). PMID: 23748486
The impact of the granulocyte colony-stimulating factor on chemotherapy dose intensity and cancer survival: a systematic review and meta-analysis of randomized controlled trials.
G H Lyman, D C Dale, +5 authors, J Crawford.
Ann Oncol, 2013 Jun 22; 24(10). PMID: 23788754    Free PMC article.
Systematic Review.
The effects of antioxidants on gene expression following gamma-radiation (GR) and proton radiation (PR) in mice in vivo.
Niklas Finnberg, Chris Wambi, Ann R Kennedy, Wafik S El-Deiry.
Cell Cycle, 2013 Jun 26; 12(14). PMID: 23797590    Free PMC article.
Filgrastim XM02 (Tevagrastim®) after autologous stem cell transplantation compared to lenograstim: favourable cost-efficacy analysis.
A Gardellini, F Gigli, +5 authors, D Laszlo.
Ecancermedicalscience, 2013 Jul 03; 7. PMID: 23818939    Free PMC article.
Use of azacitidine for myelodysplastic syndromes: controversial issues and practical recommendations.
Yoo-Jin Kim, Jun Ho Jang, +2 authors, Hyeoung-Joon Kim.
Blood Res, 2013 Jul 05; 48(2). PMID: 23826577    Free PMC article.
Chemotherapy dosing in overweight and obese patients with cancer.
Gary H Lyman, Alex Sparreboom.
Nat Rev Clin Oncol, 2013 Jul 17; 10(8). PMID: 23856744
Comparison of pegfilgrastim prescribing practice to national guidelines at a university hospital outpatient oncology clinic.
Geralyn E Waters, Patricia Corrigan, Mandy Gatesman, Thomas J Smith.
J Oncol Pract, 2013 Aug 15; 9(4). PMID: 23942922    Free PMC article.
Febrile neutropenia in hematologic malignancies.
Michael K Keng, Mikkael A Sekeres.
Curr Hematol Malig Rep, 2013 Aug 31; 8(4). PMID: 23990311
Germline genetic variants in ABCB1, ABCC1 and ALDH1A1, and risk of hematological and gastrointestinal toxicities in a SWOG Phase III trial S0221 for breast cancer.
S Yao, L E Sucheston, +18 authors, C B Ambrosone.
Pharmacogenomics J, 2013 Sep 04; 14(3). PMID: 23999597    Free PMC article.
Efficacy of deferred dosing of granulocyte colony-stimulating factor in autologous hematopoietic transplantation for multiple myeloma.
J E Cox, S Campos, +7 authors, R T Kamble.
Bone Marrow Transplant, 2013 Oct 08; 49(2). PMID: 24096822    Free PMC article.
Benefit risk assessment and update on the use of docetaxel in the management of breast cancer.
Scheryll Alken, Catherine M Kelly.
Cancer Manag Res, 2013 Oct 22; 5. PMID: 24143122    Free PMC article.
Neutropenia management and granulocyte colony-stimulating factor use in patients with solid tumours receiving myelotoxic chemotherapy--findings from clinical practice.
K Krzemieniecki, P Sevelda, +7 authors, J Maenpaa.
Support Care Cancer, 2013 Oct 25; 22(3). PMID: 24154740    Free PMC article.
Helical irradiation of the total skin with dose painting to replace total skin electron beam therapy for therapy-refractory cutaneous CD4+ T-cell lymphoma.
Chen-Hsi Hsieh, Pei-Wei Shueng, +7 authors, Yu-Jen Chen.
Biomed Res Int, 2013 Nov 01; 2013. PMID: 24175298    Free PMC article.
Study design: two long-term observational studies of the biosimilar filgrastim Nivestim™ (Hospira filgrastim) in the treatment and prevention of chemotherapy-induced neutropenia.
Didier Kamioner, Stefan Fruehauf, +3 authors, Christian Berthou.
BMC Cancer, 2013 Nov 19; 13. PMID: 24237790    Free PMC article.
Efficacy and safety analysis of once per cycle pegfilgrastim and daily lenograstim in patients with breast cancer receiving adjuvant myelosuppressive chemotherapy FEC 100: a pilot study.
Luigi Rossi, Federica Tomao, +10 authors, Silverio Tomao.
Ther Clin Risk Manag, 2013 Nov 21; 9. PMID: 24255599    Free PMC article.
A prospective observational study to evaluate G-CSF usage in patients with solid tumors receiving myelosuppressive chemotherapy in Italian clinical oncology practice.
S Barni, V Lorusso, +10 authors, P Pronzato.
Med Oncol, 2013 Dec 07; 31(1). PMID: 24307348
Carboplatin (renally dosed) and Etoposide regimen for small-cell lung cancer.
Matthew R Rutledge, J Aubrey Waddell, Dominic A Solimando.
Hosp Pharm, 2014 Jan 15; 48(4). PMID: 24421475    Free PMC article.
Docetaxel and Cisplatin regimen for non-small-cell lung cancer.
Jessie Yang, Dominic A Solimando, J Aubrey Waddell.
Hosp Pharm, 2014 Jan 15; 48(7). PMID: 24421519    Free PMC article.
Gefitinib, Fluorouracil, Oxaliplatin, and Leucovorin (IFOX) Regimen for Colorectal Cancer.
Alicia S Chen, Dominic A Solimando, J Aubrey Waddell.
Hosp Pharm, 2014 Jan 30; 48(11). PMID: 24474830    Free PMC article.
Granulocyte colony-stimulating factor (G-CSF) patterns of use in cancer patients receiving myelosuppressive chemotherapy.
Mi Rim Choi, Craig A Solid, +4 authors, Thomas J Arneson.
Support Care Cancer, 2014 Feb 05; 22(6). PMID: 24492928
Expert panel consensus statement on the optimal use of pomalidomide in relapsed and refractory multiple myeloma.
M A Dimopoulos, X Leleu, +14 authors, J F S Miguel.
Leukemia, 2014 Feb 06; 28(8). PMID: 24496300    Free PMC article.
Biosimilar G-CSF based mobilization of peripheral blood hematopoietic stem cells for autologous and allogeneic stem cell transplantation.
Michael Schmitt, Amy Publicover, +7 authors, Arnon Nagler.
Theranostics, 2014 Feb 08; 4(3). PMID: 24505236    Free PMC article.
Impact of granulocyte colony-stimulating factors in metastatic colorectal cancer patients.
A Amadio, R Burkes, +2 authors, B Coleman.
Curr Oncol, 2014 Feb 14; 21(1). PMID: 24523621    Free PMC article.
Retrospective analysis of the use of G-CSF and its impact on dose response for anthracycline plus taxane-based schedules in early breast cancer.
J A Pérez-Fidalgo, B Bermejo, +7 authors, A Lluch.
Clin Transl Oncol, 2014 Feb 18; 16(9). PMID: 24532305    Free PMC article.
Severe neutropenia and relative dose intensity among patients<65 and ≥65 years with non-Hodgkin's lymphoma receiving CHOP-based chemotherapy.
Lee S Schwartzberg, Mansoor Saleh, Sadie Whittaker, Esteban Abella.
Support Care Cancer, 2014 Feb 19; 22(7). PMID: 24535242
Reducing febrile neutropenia rates in early breast cancer. Experience of two UK cancer centres.
A P Mullard, V Misra, +3 authors, Z Malik.
Support Care Cancer, 2014 Mar 07; 22(8). PMID: 24595405
Capecitabine and Gemcitabine (CapGem, CG, GemCap) for Advanced Pancreatic and Biliary Tract Cancer.
Dominic A Solimando, J Aubrey Waddell.
Hosp Pharm, 2014 Mar 14; 49(2). PMID: 24623866    Free PMC article.
Multivariable regression analysis of febrile neutropenia occurrence in early breast cancer patients receiving chemotherapy assessing patient-related, chemotherapy-related and genetic risk factors.
Alena M Pfeil, Christof Vulsteke, +8 authors, Hans Wildiers.
BMC Cancer, 2014 Mar 20; 14. PMID: 24641830    Free PMC article.
Use of pegfilgrastim primary prophylaxis and risk of infection, by chemotherapy cycle and regimen, among patients with breast cancer or non-Hodgkin's lymphoma.
Wendy J Langeberg, Conchitina C Siozon, +2 authors, Victoria M Chia.
Support Care Cancer, 2014 Mar 22; 22(8). PMID: 24652049
Patterns of chemotherapy-associated toxicity and supportive care in US oncology practice: a nationwide prospective cohort study.
Eva Culakova, Ramya Thota, +5 authors, Gary H Lyman.
Cancer Med, 2014 Apr 08; 3(2). PMID: 24706592    Free PMC article.
Use of G-CSF to hasten neutrophil recovery after auto-SCT for AML is not associated with increased relapse incidence: a report from the Acute Leukemia Working Party of the EBMT.
T Czerw, M Labopin, +10 authors, M Mohty.
Bone Marrow Transplant, 2014 Apr 09; 49(7). PMID: 24710564
Present status of adjuvant chemotherapy for elderly breast cancer patients.
Sibylle Loibl, Mattea Reinisch.
Breast Care (Basel), 2012 Dec 01; 7(6). PMID: 24715824    Free PMC article.
Filgrastim, lenograstim and pegfilgrastim in the mobilization of peripheral blood progenitor cells in patients with lymphoproliferative malignancies.
Roberto Ria, Antonia Reale, +3 authors, Angelo Vacca.
Clin Exp Med, 2014 Apr 12; 15(2). PMID: 24722996    Free PMC article.
Supportive care in hemato-oncology: a review in light of the latest guidelines.
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Turk J Haematol, 2012 Mar 01; 29(1). PMID: 24744617    Free PMC article.
Use of colony-stimulating factor in patients with ovarian cancer receiving paclitaxel and carboplatin in Japan.
Kenichi Harano, Akihiro Hirakawa, +3 authors, Noriyuki Katsumata.
J Gynecol Oncol, 2014 Apr 25; 25(2). PMID: 24761216    Free PMC article.
The use of granulocyte colony-stimulating factors in a Canadian outpatient setting.
S Fine, M Koo, +4 authors, N Mittmann.
Curr Oncol, 2014 Apr 26; 21(2). PMID: 24764708    Free PMC article.
Risk and consequences of chemotherapy-induced neutropenic complications in patients receiving daily filgrastim: the importance of duration of prophylaxis.
Derek Weycker, Rich Barron, +3 authors, Andrew G Glass.
BMC Health Serv Res, 2014 Apr 29; 14. PMID: 24767095    Free PMC article.
Efficacy and safety of early G-CSF administration in patients with head and neck cancer treated by docetaxel-cisplatin and 5-fluorouracil (DCF protocol): a retrospective study.
B Linot, P Augereau, +2 authors, O Capitain.
Support Care Cancer, 2014 May 14; 22(10). PMID: 24821366
Incidence and management of adverse events in patients with relapsed and/or refractory multiple myeloma receiving single-agent carfilzomib.
R Donald Harvey.
Clin Pharmacol, 2014 May 24; 6. PMID: 24855395    Free PMC article.
Radio(chemo)therapy in Elderly Patients with Esophageal Cancer: A Feasible Treatment with an Outcome Consistent with Younger Patients.
Philippe Rochigneux, Michel Resbeut, +4 authors, Laurence Moureau-Zabotto.
Front Oncol, 2014 May 27; 4. PMID: 24860783    Free PMC article.
Lenalidomide and rituximab for the initial treatment of patients with chronic lymphocytic leukemia: a multicenter clinical-translational study from the chronic lymphocytic leukemia research consortium.
Danelle F James, Lillian Werner, +9 authors, Thomas J Kipps.
J Clin Oncol, 2014 May 29; 32(19). PMID: 24868031    Free PMC article.
Safety profile of Pertuzumab with Trastuzumab and Docetaxel in patients from Asia with human epidermal growth factor receptor 2-positive metastatic breast cancer: results from the phase III trial CLEOPATRA.
Sandra M Swain, Young-Hyuck Im, +6 authors, José Baselga.
Oncologist, 2014 May 30; 19(7). PMID: 24869931    Free PMC article.
Presentation and management of docetaxel-related adverse effects in patients with breast cancer.
Maria Y Ho, John R Mackey.
Cancer Manag Res, 2014 Jun 07; 6. PMID: 24904223    Free PMC article.
Clinical predictive models for chemotherapy-induced febrile neutropenia in breast cancer patients: a validation study.
Kai Chen, Xiaolan Zhang, +4 authors, Xiaogeng Deng.
PLoS One, 2014 Jun 20; 9(6). PMID: 24945817    Free PMC article.
Paclitaxel and trastuzumab for breast cancer.
Thomas Lehmann, Dominic A Solimando, J Aubrey Waddell.
Hosp Pharm, 2014 Jun 25; 49(4). PMID: 24958939    Free PMC article.
Paclitaxel and Carboplatin (TC) Regimen for Ovarian Cancer.
Julie M Akin, J Aubrey Waddell, Dominic A Solimando.
Hosp Pharm, 2014 Jun 25; 49(5). PMID: 24958952    Free PMC article.
Gemcitabine and Vinorelbine (GemVin) Regimen.
Elizabeth Y Shang, Dominic A Solimando, J Aubrey Waddell.
Hosp Pharm, 2014 Jun 25; 49(6). PMID: 24958967    Free PMC article.
Incidence of febrile neutropenia in early stage breast cancer patients receiving adjuvant FEC-D treatment.
Hazem Assi, Joshua Murray, Laura Boyle, Daniel Rayson.
Support Care Cancer, 2014 Jul 06; 22(12). PMID: 24996828
Risk factors for febrile neutropenia in patients receiving docetaxel chemotherapy for castration-resistant prostate cancer.
Masaki Shiota, Akira Yokomizo, +4 authors, Seiji Naito.
Support Care Cancer, 2014 Jul 06; 22(12). PMID: 24996830
Neutropenia and relative dose intensity on adjuvant FOLFOX chemotherapy are not associated with survival for resected colon cancer.
Martin Smoragiewicz, Khodadad R Javaheri, Yaling Yin, Sharlene Gill.
J Gastrointest Cancer, 2014 Jul 12; 45(4). PMID: 25012517
Risk of febrile neutropenia in patients receiving emerging chemotherapy regimens.
Derek Weycker, Xiaoyan Li, +4 authors, Gary H Lyman.
Support Care Cancer, 2014 Aug 02; 22(12). PMID: 25082364
Preventing infections during cancer treatment: development of an interactive patient education website.
Angela Dunbar, Eric Tai, +2 authors, Lisa C Richardson.
Clin J Oncol Nurs, 2014 Aug 06; 18(4). PMID: 25095295    Free PMC article.
Granulocyte colony-stimulating factor use in a large British hospital: comparison with published experience.
Román Pérez Velasco.
Pharm Pract (Granada), 2010 Oct 01; 8(4). PMID: 25126143    Free PMC article.
Impact of pegylated filgrastim in comparison to filgrastim for patients with acute myeloid leukaemia (AML) on high-dose cytarabine (HIDAC) consolidation chemotherapy.
Grace Kam, Richard Yiu, +4 authors, Gee Chuan Wong.
Support Care Cancer, 2014 Aug 28; 23(3). PMID: 25160495
Model-based approach to early predict prolonged high grade neutropenia in carboplatin-treated patients and guide G-CSF prophylactic treatment.
Mélanie L Pastor, Céline M Laffont, +2 authors, Didier Concordet.
Pharm Res, 2014 Sep 05; 32(2). PMID: 25186439
Predictive factors for severe and febrile neutropenia during docetaxel chemotherapy for castration-resistant prostate cancer.
Keisuke Shigeta, Takeo Kosaka, +10 authors, Mototsugu Oya.
Int J Clin Oncol, 2014 Sep 10; 20(3). PMID: 25196861
Increasing utilization and predictors of hematopoietic growth factors in patients diagnosed with colorectal cancer: findings from a large national population-based cohort in the USA, 1992-2009.
Yefei Zhang, Shuang-Shuang Fu, Xianglin L Du.
Med Oncol, 2014 Sep 19; 31(10). PMID: 25231751
The prophylactic effects of a traditional Japanese medicine, goshajinkigan, on paclitaxel-induced peripheral neuropathy and its mechanism of action.
Yukiko Matsumura, Yoshihito Yokoyama, +3 authors, Hideki Mizunuma.
Mol Pain, 2014 Sep 23; 10. PMID: 25240613    Free PMC article.
A randomized, double-blind, active control, multicenter, dose-finding study of lipegfilgrastim (XM22) in breast cancer patients receiving myelosuppressive therapy.
Anton Buchner, Reiner Elsässer, Peter Bias.
Breast Cancer Res Treat, 2014 Sep 28; 148(1). PMID: 25261291    Free PMC article.
Efficacy, effectiveness and safety of long-acting granulocyte colony-stimulating factors for prophylaxis of chemotherapy-induced neutropenia in patients with cancer: a systematic review.
Alena M Pfeil, Kim Allcott, +3 authors, Zsolt Szabo.
Support Care Cancer, 2014 Oct 07; 23(2). PMID: 25284721
Systematic Review.
Granulocyte colony-stimulating factors as prophylaxis against febrile neutropenia.
Sol Cortés de Miguel, Miguel Ángel Calleja-Hernández, Salomón Menjón-Beltrán, Inmaculada Vallejo-Rodríguez.
Support Care Cancer, 2014 Oct 07; 23(2). PMID: 25284722
Clinical practice guidelines and consensus statements in oncology--an assessment of their methodological quality.
Carmel Jacobs, Ian D Graham, +4 authors, Mark Clemons.
PLoS One, 2014 Oct 21; 9(10). PMID: 25329669    Free PMC article.
Adjuvant Docetaxel and Cyclophosphamide (DC) with prophylactic granulocyte colony-stimulating factor (G-CSF) on days 8 &12 in breast cancer patients: a retrospective analysis.
Rinat Yerushalmi, Hadar Goldvaser, +10 authors, Salomon M Stemmer.
PLoS One, 2014 Oct 21; 9(10). PMID: 25330205    Free PMC article.
Update on adjuvant chemotherapy for early breast cancer.
Murtuza M Rampurwala, Gabrielle B Rocque, Mark E Burkard.
Breast Cancer (Auckl), 2014 Oct 23; 8. PMID: 25336961    Free PMC article.
Pegfilgrastim in primary prophylaxis of febrile neutropenia during chemotherapy of relapsed and refractory multiple myeloma: a real-life experience.
Claudio Cerchione, Lucio Catalano, +2 authors, Fabrizio Pane.
Support Care Cancer, 2014 Oct 25; 23(2). PMID: 25341551
Preclinical profile of cabazitaxel.
Patricia Vrignaud, Dorothée Semiond, +3 authors, Sunil Gupta.
Drug Des Devel Ther, 2014 Nov 08; 8. PMID: 25378905    Free PMC article.
Pharmacokinetic study of aldoxorubicin in patients with solid tumors.
Monica M Mita, Ronald B Natale, +5 authors, Alain C Mita.
Invest New Drugs, 2014 Nov 13; 33(2). PMID: 25388939    Free PMC article.
Management of breast cancer patients with chemotherapy-induced neutropenia or febrile neutropenia.
Caterina Fontanella, Silvia Bolzonello, Bianca Lederer, Giuseppe Aprile.
Breast Care (Basel), 2014 Nov 19; 9(4). PMID: 25404882    Free PMC article.
Patterns of neutropenia and risk factors for febrile neutropenia of diffuse large B-cell lymphoma patients treated with rituximab-CHOP.
Yong Won Choi, Seong Hyun Jeong, +5 authors, Joon Seong Park.
J Korean Med Sci, 2014 Nov 20; 29(11). PMID: 25408580    Free PMC article.
G-CSF utilization rate and prescribing patterns in United States: associations between physician and patient factors and GCSF use.
Gisoo Barnes, Ashutosh Pathak, Lee Schwartzberg.
Cancer Med, 2014 Nov 21; 3(6). PMID: 25410813    Free PMC article.
A prospectively validated nomogram for predicting the risk of chemotherapy-induced febrile neutropenia: a multicenter study.
H Bozcuk, M Yıldız, +10 authors, B Savas.
Support Care Cancer, 2014 Dec 01; 23(6). PMID: 25433439
Paclitaxel, Carboplatin, and trastuzumab.
Jennifer Lee, Dominic A Solimando, J Aubrey Waddell.
Hosp Pharm, 2014 Dec 06; 49(10). PMID: 25477563    Free PMC article.
Irinotecan and Carboplatin (IC) Regimen for Small-Cell Lung Cancer and Non-Small-Cell Lung Cancer.
Matthew R Rutledge, J Aubrey Waddell, Dominic A Solimando.
Hosp Pharm, 2014 Dec 06; 49(7). PMID: 25477577    Free PMC article.
Comparison of filgrastim and pegfilgrastim to prevent neutropenia and maintain dose intensity of adjuvant chemotherapy in patients with breast cancer.
Georgia Kourlaba, Meletios A Dimopoulos, +6 authors, Nikos Maniadakis.
Support Care Cancer, 2014 Dec 20; 23(7). PMID: 25524005
Modelling chemotherapy effects on granulopoiesis.
Sibylle Schirm, Christoph Engel, Markus Loeffler, Markus Scholz.
BMC Syst Biol, 2014 Dec 30; 8. PMID: 25539928    Free PMC article.
Safety and tolerability of docetaxel, cyclophosphamide, and trastuzumab compared to standard trastuzumab-based chemotherapy regimens for early-stage human epidermal growth factor receptor 2-positive breast cancer.
Potjana Jitawatanarat, Tracey L O'Connor, +3 authors, Nuttapong Ngamphaiboon.
J Breast Cancer, 2014 Dec 31; 17(4). PMID: 25548584    Free PMC article.
Pharmacotherapy for adverse events reduces the length of hospital stay in patients admitted to otolaryngology ward: a single arm intervention study.
Akio Suzuki, Ryo Kobayashi, +4 authors, Yoshinori Itoh.
PLoS One, 2014 Dec 31; 9(12). PMID: 25549093    Free PMC article.
Phase III placebo-controlled, double-blind, randomized trial of pegfilgrastim to reduce the risk of febrile neutropenia in breast cancer patients receiving docetaxel/cyclophosphamide chemotherapy.
Yoshimasa Kosaka, Yoshiaki Rai, +7 authors, Kazuo Tamura.
Support Care Cancer, 2015 Jan 13; 23(4). PMID: 25576433    Free PMC article.
Pegfilgrastim vs filgrastim in PBSC mobilization for autologous hematopoietic SCT: a systematic review and meta-analysis.
M G Kim, N Han, E-K Lee, T Kim.
Bone Marrow Transplant, 2015 Jan 13; 50(4). PMID: 25581410
Systematic Review.
Comparison of Therapeutic G-CSF Cycles and Prophylactic G-CSF Cycles in Patients Receiving Paclitaxel and Carboplatin Combination Chemotherapy for Ovarian Cancer: A Retrospective Study Report.
Masaaki Kawashima, Hajime Kondo.
J Rural Med, 2015 Feb 05; 9(2). PMID: 25648659    Free PMC article.
The signs, symptoms and help-seeking experiences of neutropenic sepsis patients before they reach hospital: a qualitative study.
Rachel T Clarke, Sarah Bird, +2 authors, Victoria van Hamel Parsons.
Support Care Cancer, 2015 Feb 11; 23(9). PMID: 25663575
Bortezomib, Melphalan, and Prednisone (VMP) Regimen for Multiple Myeloma.
Samantha Bryant, Dominic A Solimando, J Aubrey Waddell.
Hosp Pharm, 2015 Feb 17; 50(1). PMID: 25684797    Free PMC article.
Pertuzumab, trastuzumab, and docetaxel in HER2-positive metastatic breast cancer.
Sandra M Swain, José Baselga, +12 authors, CLEOPATRA Study Group.
N Engl J Med, 2015 Feb 19; 372(8). PMID: 25693012    Free PMC article.
Highly Cited.
Phase I and pharmacokinetic study of the novel anthracycline derivative 5-imino-13-deoxydoxorubicin (GPX-150) in patients with advanced solid tumors.
Sarah A Holstein, James C Bigelow, +3 authors, Raymond J Hohl.
Invest New Drugs, 2015 Feb 24; 33(3). PMID: 25698442
Does procalcitonin, C-reactive protein, or interleukin-6 test have a role in the diagnosis of severe infection in patients with febrile neutropenia? A systematic review and meta-analysis.
Chun-Wei Wu, Jiunn-Yih Wu, +5 authors, Chien-Chang Lee.
Support Care Cancer, 2015 Feb 24; 23(10). PMID: 25701436
Systematic Review.
Dose response of pegfilgrastim in Japanese breast cancer patients receiving six cycles of docetaxel, doxorubicin, and cyclophosphamide therapy: a randomized controlled trial.
Norikazu Masuda, Yutaka Tokuda, +3 authors, Kazuo Tamura.
Support Care Cancer, 2015 Mar 04; 23(10). PMID: 25733000    Free PMC article.
Safety and efficacy of granulocyte colony-stimulating factor biosimilars in engraftment after autologous stem cell transplantation for haematological malignancies: a 4-year, single institute experience with different conditioning regimens.
Simona Bassi, Elisa M Stroppa, +11 authors, Daniele Vallisa.
Blood Transfus, 2015 Mar 12; 13(3). PMID: 25761321    Free PMC article.
The evolving role of cytotoxic chemotherapy in the management of patients with metastatic prostate cancer.
Elan Diamond, María del Carmen Garcias, Beerinder Karir, Scott T Tagawa.
Curr Treat Options Oncol, 2015 Mar 13; 16(2). PMID: 25762124
Clinical practice in febrile neutropenia risk assessment and granulocyte colony-stimulating factor primary prophylaxis of febrile neutropenia in Poland.
Marek Wojtukiewicz, Ewa Chmielowska, +5 authors, Elżbieta Kosno-Kruszewska.
Contemp Oncol (Pozn), 2014 Jan 01; 18(6). PMID: 25784841    Free PMC article.
Assessing patients' risk of febrile neutropenia: is there a correlation between physician-assessed risk and model-predicted risk?
Gary H Lyman, David C Dale, +4 authors, Jeffrey Crawford.
Cancer Med, 2015 Mar 27; 4(8). PMID: 25810005    Free PMC article.
An open-label, randomized, multicenter dose-finding study of once-per-cycle pegfilgrastim versus daily filgrastim in Chinese breast cancer patients receiving TAC chemotherapy.
Wei Zhang, Zhiwei Jiang, +2 authors, Jielai Xia.
Med Oncol, 2015 Mar 31; 32(5). PMID: 25820754
The impact of primary prophylaxis with granulocyte colony-stimulating factors on febrile neutropenia during chemotherapy: a systematic review and meta-analysis of randomized controlled trials.
Li Wang, Onur Baser, +2 authors, Richard Barron.
Support Care Cancer, 2015 Mar 31; 23(11). PMID: 25821144    Free PMC article.
Systematic Review.
Differential Impact of Relative Dose-Intensity Reductions in Diffuse Large B-Cell Lymphoma Treated with R-CHOP21 or R-CHOP14.
Antonio Gutiérrez, Leyre Bento, +19 authors, Joan Besalduch.
PLoS One, 2015 Apr 25; 10(4). PMID: 25909361    Free PMC article.
Incidence of bone pain in patients with breast cancer treated with lipegfilgrastim or pegfilgrastim: an integrated analysis from phase II and III studies.
I M Bondarenko, P Bias, A Buchner.
Support Care Cancer, 2015 May 31; 24(1). PMID: 26024743
Febrile neutropenia in chemotherapy treated small-cell lung cancer patients.
Renata Rezonja Kukec, Iztok Grabnar, +3 authors, Tanja Cufer.
Radiol Oncol, 2015 Jun 02; 49(2). PMID: 26029029    Free PMC article.
Phase II study of lapatinib in combination with vinorelbine, as first or second-line therapy in women with HER2 overexpressing metastatic breast cancer.
Helen Kent Chew, Lee Schwartzberg, +5 authors, Janine Mahoney.
Springerplus, 2014 Jan 01; 3. PMID: 26034656    Free PMC article.
Adherence to granulocyte-colony stimulating factor (G-CSF) guidelines to reduce the incidence of febrile neutropenia after chemotherapy--a representative sample survey in Germany.
Hartmut Link, J Nietsch, +2 authors, Supportive Care Group (ASORS) of the German Cancer Society (DKG).
Support Care Cancer, 2015 Jun 18; 24(1). PMID: 26081593
Phase 1 study of the investigational Aurora A kinase inhibitor alisertib (MLN8237) in East Asian cancer patients: pharmacokinetics and recommended phase 2 dose.
Karthik Venkatakrishnan, Tae Min Kim, +8 authors, Won Seog Kim.
Invest New Drugs, 2015 Jun 19; 33(4). PMID: 26084989
Chemotherapy-associated treatment burden in breast cancer patients receiving lipegfilgrastim or pegfilgrastim: secondary efficacy data from a phase III study.
Oleg A Gladkov, Anton Buchner, +2 authors, Reiner Elsässer.
Support Care Cancer, 2015 Jun 21; 24(1). PMID: 26092233
Epidemiology and characteristics of febrile neutropenia in oncology patients from Spanish tertiary care hospitals: PINNACLE study.
Javier DE Castro Carpeño, Pere Gascón-Vilaplana, +8 authors, Francisco José Rebollo Laserna.
Mol Clin Oncol, 2015 Jul 03; 3(3). PMID: 26137294    Free PMC article.
Phase III, randomized, double-blind, placebo-controlled, multicenter study of lipegfilgrastim in patients with non-small cell lung cancer receiving myelosuppressive therapy.
Constantin Volovat, Igor M Bondarenko, +4 authors, Udo Müller.
Springerplus, 2015 Jul 15; 4. PMID: 26155455    Free PMC article.
Risk factors for bone pain among patients with cancer receiving myelosuppressive chemotherapy and pegfilgrastim.
H Xu, Q Gong, +2 authors, J H Page.
Support Care Cancer, 2015 Jul 15; 24(2). PMID: 26162536
Utility of the Multinational Association for Supportive Care in Cancer (MASCC) Risk Index Score as a Criterion for Nonadmission in Febrile Neutropenic Patients with Solid Tumors.
Roger A Bitar.
Perm J, 2015 Jul 16; 19(3). PMID: 26176568    Free PMC article.
The impact of chemotherapy dose intensity and supportive care on the risk of febrile neutropenia in patients with early stage breast cancer: a prospective cohort study.
Eva Culakova, Marek S Poniewierski, +3 authors, Gary H Lyman.
Springerplus, 2015 Aug 08; 4. PMID: 26251780    Free PMC article.
G-CSF and GM-CSF in Neutropenia.
Hrishikesh M Mehta, Michael Malandra, Seth J Corey.
J Immunol, 2015 Aug 09; 195(4). PMID: 26254266    Free PMC article.
Chemotherapy-induced neutropenia and febrile neutropenia in patients with gynecologic malignancy.
Yasunori Hashiguchi, Mari Kasai, +3 authors, Toshiyuki Sumi.
Anticancer Drugs, 2015 Aug 13; 26(10). PMID: 26267078    Free PMC article.
Risk factors for second acute myeloid leukemia/myelodysplastic syndrome among survivors of non-Hodgkin lymphoma.
C J K Lam, R E Curtis, +10 authors, L M Morton.
Leukemia, 2015 Sep 16; 30(5). PMID: 26369985    Free PMC article.
Phase 1 study of oral TAS-102 in patients with refractory metastatic colorectal cancer.
Johanna C Bendell, Lee S Rosen, +7 authors, Manish R Patel.
Cancer Chemother Pharmacol, 2015 Sep 16; 76(5). PMID: 26370544    Free PMC article.
[Neoadjuvant therapy for tumors of the upper gastrointestinal tract : Complication management].
I Gockel, A Hoffmeister, F Lordick.
Chirurg, 2015 Sep 17; 86(11). PMID: 26374651
Measuring the impact of guideline-based antiemetic therapy on nausea and vomiting control in breast cancer patients with multiple risk factors.
George Dranitsaris, Sasha Mazzarello, +3 authors, Mark Clemons.
Support Care Cancer, 2015 Sep 19; 24(4). PMID: 26381427
Doxorubicin and Dacarbazine (AD) Regimen for Soft Tissue Sarcomas.
Kyle E Adkins, Dominic A Solimando, J Aubrey Waddell.
Hosp Pharm, 2015 Sep 26; 50(3). PMID: 26405307    Free PMC article.
Oncological emergencies associated with gastrointestinal tumors.
Klaas Prenen, Hans Prenen.
Ann Gastroenterol, 2015 Oct 02; 28(4). PMID: 26424367    Free PMC article.
Attitudes and practice patterns for maintaining relative dose intensity of chemotherapy in outpatient clinics: results of a Japanese web-based survey.
Hitomi Sakai, Noriyuki Katsumata, Genmu Kadokura.
BMC Cancer, 2015 Oct 07; 15. PMID: 26438185    Free PMC article.
Myelodysplastic syndrome and acute myeloid leukemia following adjuvant chemotherapy with and without granulocyte colony-stimulating factors for breast cancer.
Gregory S Calip, Judith A Malmgren, +2 authors, Henry G Kaplan.
Breast Cancer Res Treat, 2015 Oct 10; 154(1). PMID: 26450505    Free PMC article.
Prophylactic long-acting granulocyte-colony stimulating factors (G-CSF) in gynecologic malignancies: an oncologic expert statement.
Edgar Petru, Christian F Singer, +12 authors, Alain-Gustave Zeimet.
Wien Med Wochenschr, 2015 Oct 17; 165(19-20). PMID: 26471371
Zarzio®, biosimilar of filgrastim, in prophylaxis of chemotherapy-induced neutropenia in routine practice: a French prospective multicentric study.
Sophie Nahon, Mansour Rastkhah, +3 authors, Jean-Luc Labourey.
Support Care Cancer, 2015 Oct 29; 24(5). PMID: 26507190    Free PMC article.
Multicentre, Prospective Observational Study of Pegfilgrastim Primary Prophylaxis in Patients at High Risk of Febrile Neutropenia in Poland: PROFIL Study.
Wojciech Jurczak, Ewa Kalinka-Warzocha, +3 authors, Karolina Wieruszewska.
Contemp Oncol (Pozn), 2015 Nov 12; 19(3). PMID: 26557762    Free PMC article.
Optimal use of bendamustine in hematologic disorders: Treatment recommendations from an international consensus panel - an update.
Bruce D Cheson, Wolfram Brugger, +7 authors, Pier Luigi Zinzani.
Leuk Lymphoma, 2015 Nov 26; 57(4). PMID: 26592922    Free PMC article.
At-home autologous stem cell transplantation in multiple myeloma with and without G-CSF administration: a comparative study.
N Martínez-Cibrian, L Magnano, +16 authors, F Fernández-Avilés.
Bone Marrow Transplant, 2015 Nov 26; 51(4). PMID: 26595072
Efficacy of trabectedin in advanced soft tissue sarcoma: beyond lipo- and leiomyosarcoma.
Rita De Sanctis, Andrea Marrari, +8 authors, Armando Santoro.
Drug Des Devel Ther, 2015 Nov 26; 9. PMID: 26604682    Free PMC article.
Phase I trial of volasertib, a Polo-like kinase inhibitor, in Japanese patients with advanced solid tumors.
Hiroshi Nokihara, Yasuhide Yamada, +9 authors, Tomohide Tamura.
Invest New Drugs, 2015 Dec 03; 34(1). PMID: 26627079
Optimizing Outcomes in Immunocompromised Hosts: Understanding the Role of Immunotherapy in Invasive Fungal Diseases.
Sharada Ravikumar, Mar Soe Win, Louis Yi Ann Chai.
Front Microbiol, 2015 Dec 05; 6. PMID: 26635780    Free PMC article.
A Phase III Study of Balugrastim Versus Pegfilgrastim in Breast Cancer Patients Receiving Chemotherapy With Doxorubicin and Docetaxel.
Oleg Gladkov, Vladimir Moiseyenko, +4 authors, Noa Avisar.
Oncologist, 2015 Dec 17; 21(1). PMID: 26668251    Free PMC article.
Risk of chemotherapy-induced febrile neutropenia with early discontinuation of pegfilgrastim prophylaxis in US clinical practice.
Derek Weycker, Xiaoyan Li, +6 authors, Jacob Garcia.
Support Care Cancer, 2015 Dec 17; 24(6). PMID: 26670915    Free PMC article.
Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial.
Nicholas D James, Matthew R Sydes, +45 authors, STAMPEDE investigators.
Lancet, 2016 Jan 01; 387(10024). PMID: 26719232    Free PMC article.
Highly Cited.
Front-line Treatment with Gemcitabine, Paclitaxel, and Doxorubicin for Patients With Unresectable or Metastatic Urothelial Cancer and Poor Renal Function: Final Results from a Phase II Study.
Arlene O Siefker-Radtke, Matthew T Campbell, +3 authors, Lance C Pagliaro.
Urology, 2016 Jan 03; 89. PMID: 26723185    Free PMC article.
Ofatumumab and Lenalidomide for Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia: Correlation between Responses and Immune Characteristics.
Candida Vitale, Lorenzo Falchi, +13 authors, Alessandra Ferrajoli.
Clin Cancer Res, 2016 Jan 07; 22(10). PMID: 26733610    Free PMC article.
Results of a prospective dose intensity and neutropenia prophylaxis evaluation programme (DIEPP) in cancer patients at risk of febrile neutropenia due to myelosuppressive chemotherapy.
Radosław Mądry, Lidia Popławska, +10 authors, Christine Staudigl.
Wien Klin Wochenschr, 2016 Jan 10; 128(7-8). PMID: 26745973    Free PMC article.
Amrubicin for relapsed small-cell lung cancer: a systematic review and meta-analysis of 803 patients.
Nobuyuki Horita, Masaki Yamamoto, +13 authors, Takeshi Kaneko.
Sci Rep, 2016 Jan 12; 6. PMID: 26750506    Free PMC article.
Systematic Review.
Adjuvant treatment for older women with invasive breast cancer.
Trevor A Jolly, Grant R Williams, +4 authors, Hyman B Muss.
Womens Health (Lond), 2016 Jan 16; 12(1). PMID: 26767315    Free PMC article.
Clinical safety of tbo-filgrastim, a short-acting human granulocyte colony-stimulating factor.
Ruth Pettengell, Peter Bias, Udo Mueller, Nicole Lang.
Support Care Cancer, 2016 Jan 19; 24(6). PMID: 26780505
Granulocyte growth factor use in elderly patients with non-Hodgkin's lymphoma in the United States: adherence to guidelines and comparative effectiveness.
Linda S Elting, Ying Xu, Mariana Chavez-MacGregor, Sharon H Giordano.
Support Care Cancer, 2016 Jan 23; 24(6). PMID: 26797253
PEPCOL: a GERCOR randomized phase II study of nanoliposomal irinotecan PEP02 (MM-398) or irinotecan with leucovorin/5-fluorouracil as second-line therapy in metastatic colorectal cancer.
Benoist Chibaudel, Frédérique Maindrault-Gœbel, +15 authors, Aimery de Gramont.
Cancer Med, 2016 Jan 26; 5(4). PMID: 26806397    Free PMC article.
Bevacizumab and Temozolomide Plus Radiation Regimen for Glioblastoma Multiforme.
Matthew R Rutledge, J Aubrey Waddell, Dominic A Solimando.
Hosp Pharm, 2016 Jan 30; 50(8). PMID: 26823616    Free PMC article.
Examination of the clinical efficacy of eribulin and trastuzumab in HER2-positive recurrent breast cancer.
Takayoshi Kiba, Nao Morii, +5 authors, Hiroyasu Yamashiro.
Mol Clin Oncol, 2016 Feb 13; 4(1). PMID: 26870356    Free PMC article.
Routine Primary Prophylaxis for Febrile Neutropenia with Biosimilar Granulocyte Colony-Stimulating Factor (Nivestim) or Pegfilgrastim Is Cost Effective in Non-Hodgkin Lymphoma Patients undergoing Curative-Intent R-CHOP Chemotherapy.
Xiao Jun Wang, Tiffany Tang, +5 authors, Alexandre Chan.
PLoS One, 2016 Feb 13; 11(2). PMID: 26871584    Free PMC article.
Randomized phase II study of loratadine for the prevention of bone pain caused by pegfilgrastim.
J Moukharskaya, D M Abrams, +9 authors, S Ades.
Support Care Cancer, 2016 Feb 20; 24(7). PMID: 26894485    Free PMC article.
Responding to Acute Care Needs of Patients With Cancer: Recent Trends Across Continents.
Alison Young, Ernie Marshall, +9 authors, Peter Selby.
Oncologist, 2016 Feb 28; 21(3). PMID: 26921289    Free PMC article.
Biosimilars in the management of neutropenia: focus on filgrastim.
Désirée Caselli, Simone Cesaro, Maurizio Aricò.
Biologics, 2016 Mar 05; 10. PMID: 26937170    Free PMC article.
Impact of an electronic tool in prescribing primary prophylaxis with ciprofloxacin or granulocyte colony-stimulating factor for breast cancer patients receiving TC chemotherapy.
Jeffrey Sulpher, Pierre Giguere, Sean Hopkins, Susan Dent.
Support Care Cancer, 2016 Mar 05; 24(7). PMID: 26939922
Randomized, double-blind study comparing proposed biosimilar LA-EP2006 with reference pegfilgrastim in breast cancer.
Nadia Harbeck, Oleg Lipatov, +7 authors, Kimberly Blackwell.
Future Oncol, 2016 Mar 30; 12(11). PMID: 27020170    Free PMC article.
A phase II, multicenter, single-arm trial of eribulin as first-line chemotherapy for HER2-negative locally advanced or metastatic breast cancer.
Tsutomu Takashima, Shinya Tokunaga, +16 authors, Kosei Hirakawa.
Springerplus, 2016 Mar 31; 5. PMID: 27026861    Free PMC article.
Phase I Study of LY2606368, a Checkpoint Kinase 1 Inhibitor, in Patients With Advanced Cancer.
David Hong, Jeffrey Infante, +13 authors, Johanna Bendell.
J Clin Oncol, 2016 Apr 06; 34(15). PMID: 27044938    Free PMC article.
Highly Cited.
Incidence of Febrile Neutropenia in Korean Female Breast Cancer Patients Receiving Preoperative or Postoperative Doxorubicin/Cyclophosphamide Followed by Docetaxel Chemotherapy.
Chang Gon Kim, Joohyuk Sohn, +8 authors, Gun Min Kim.
J Breast Cancer, 2016 Apr 12; 19(1). PMID: 27064666    Free PMC article.
A randomized, double-blind trial of pegfilgrastim versus filgrastim for the management of neutropenia during CHASE(R) chemotherapy for malignant lymphoma.
Kohmei Kubo, Yasuhiko Miyazaki, +5 authors, Kazuo Tamura.
Br J Haematol, 2016 Apr 14; 174(4). PMID: 27072050    Free PMC article.
Chemotherapy continuity and incidence of febrile neutropenia with CHOP therapy in an outpatient setting.
Eiseki Usami, Michio Kimura, +3 authors, Tomoaki Yoshimura.
Mol Clin Oncol, 2016 Apr 14; 4(4). PMID: 27073670    Free PMC article.
A Comparison of Proposed Biosimilar LA-EP2006 and Reference Pegfilgrastim for the Prevention of Neutropenia in Patients With Early-Stage Breast Cancer Receiving Myelosuppressive Adjuvant or Neoadjuvant Chemotherapy: Pegfilgrastim Randomized Oncology (Supportive Care) Trial to Evaluate Comparative Treatment (PROTECT-2), a Phase III, Randomized, Double-Blind Trial.
Kimberly Blackwell, Roman Donskih, +7 authors, Nadia Harbeck.
Oncologist, 2016 Apr 20; 21(7). PMID: 27091420    Free PMC article.
To wake up cancer stem cells, or to let them sleep, that is the question.
Shoichiro Takeishi, Keiichi I Nakayama.
Cancer Sci, 2016 Apr 27; 107(7). PMID: 27116333    Free PMC article.
Humanized mice efficiently engrafted with fetal hepatoblasts and syngeneic immune cells develop human monocytes and NK cells.
Eva Billerbeck, Michiel C Mommersteeg, +11 authors, Ype P de Jong.
J Hepatol, 2016 May 07; 65(2). PMID: 27151182    Free PMC article.
Clinical Predictors of Venetoclax Pharmacokinetics in Chronic Lymphocytic Leukemia and Non-Hodgkin's Lymphoma Patients: a Pooled Population Pharmacokinetic Analysis.
Aksana K Jones, Kevin J Freise, +3 authors, Ahmed Hamed Salem.
AAPS J, 2016 May 29; 18(5). PMID: 27233802
Granulocyte Colony-Stimulating Factor Use in a Large Iranian Hospital: Comparison with American Society of Clinical Oncology (ASCO) Clinical Practice Guideline.
Sarah Mousavi, Mina Dadpoor, Farzaneh Ashrafi.
Int J Hematol Oncol Stem Cell Res, 2016 Jun 03; 10(2). PMID: 27252808    Free PMC article.
Oral administration of the amino acids cystine and theanine attenuates the adverse events of S-1 adjuvant chemotherapy in gastrointestinal cancer patients.
Takashi Tsuchiya, Hiroshi Honda, +8 authors, Takashi Kayahara.
Int J Clin Oncol, 2016 Jun 17; 21(6). PMID: 27306219    Free PMC article.
Cutting the brakes on hematopoietic regeneration by blocking TGFβ to limit chemotherapy-induced myelosuppression.
Fabienne Brenet, Joseph M Scandura.
Mol Cell Oncol, 2016 Jun 17; 2(3). PMID: 27308454    Free PMC article.
Carboplatin and Liposomal Doxorubicin for Ovarian Cancer.
Jamie Nguyen, Dominic A Solimando, J Aubrey Waddell.
Hosp Pharm, 2016 Jun 30; 51(6). PMID: 27354744    Free PMC article.
Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America.
Thomas F Patterson, George R Thompson, +14 authors, John E Bennett.
Clin Infect Dis, 2016 Jul 02; 63(4). PMID: 27365388    Free PMC article.
Highly Cited.
Treatment of Metastatic Colorectal Cancer Patients ≥75 Years Old in Clinical Practice: A Multicenter Analysis.
Roberta Grande, Clara Natoli, +17 authors, Teresa Gamucci.
PLoS One, 2016 Jul 22; 11(7). PMID: 27442239    Free PMC article.
Comparison of adjuvant ED and EC-D regimens in operable breast invasive ductal carcinoma.
Liyu Jiang, Chuyu Jing, +6 authors, Qifeng Yang.
Oncol Lett, 2016 Jul 23; 12(2). PMID: 27446451    Free PMC article.
Efficacy and safety of lipegfilgrastim compared with placebo in patients with non-small cell lung cancer receiving chemotherapy: post hoc analysis of elderly versus younger patients.
Constantin Volovat, Igor Bondarenko, +4 authors, Peter Bias.
Support Care Cancer, 2016 Oct 28; 24(12). PMID: 27501966
Neutrophils in the tumor microenvironment: trying to heal the wound that cannot heal.
Kelly L Singel, Brahm H Segal.
Immunol Rev, 2016 Aug 26; 273(1). PMID: 27558344    Free PMC article.
Chemotherapy-induced neutropenia among pediatric cancer patients in Egypt: Risks and consequences.
Mohamed Badr, Tamer Hassan, +5 authors, Sahbaa Fehr.
Mol Clin Oncol, 2016 Sep 03; 5(3). PMID: 27588196    Free PMC article.
Challenges in the Role of Gammaglobulin Replacement Therapy and Vaccination Strategies for Hematological Malignancy.
Silvia Sánchez-Ramón, Fatima Dhalla, Helen Chapel.
Front Immunol, 2016 Sep 07; 7. PMID: 27597852    Free PMC article.
Phase I Study of the Anti-CD22 Antibody-Drug Conjugate Pinatuzumab Vedotin with/without Rituximab in Patients with Relapsed/Refractory B-cell Non-Hodgkin Lymphoma.
Ranjana H Advani, Daniel Lebovic, +13 authors, Bruce D Cheson.
Clin Cancer Res, 2016 Sep 08; 23(5). PMID: 27601593    Free PMC article.
Cabazitaxel for Metastatic Castration-Resistant Prostate Cancer: Retrospective Data Analysis from an Indian Centre.
Vanita Noronha, Amit Joshi, +2 authors, Kumar Prabhash.
Case Rep Oncol, 2016 Oct 11; 9(2). PMID: 27721776    Free PMC article.
Managing neutropenia by pegfilgrastim in patients affected by relapsed/refractory multiple myeloma treated with bendamustine-bortezomib-dexamethasone.
Claudio Cerchione, Lucio Catalano, +6 authors, Fabrizio Pane.
Support Care Cancer, 2016 Oct 28; 24(12). PMID: 27726031    Free PMC article.
What do oncologists need to know about biosimilar products?
Linda K S Leung, Kevin Mok, Calvin Liu, Stephen L Chan.
Chin J Cancer, 2016 Oct 14; 35(1). PMID: 27733189    Free PMC article.
Burden of Chemotherapy-Induced Febrile Neutropenia Hospitalizations in US Clinical Practice, by Use and Patterns of Prophylaxis with Colony-Stimulating Factor.
Derek Weycker, Xiaoyan Li, +5 authors, Gary H Lyman.
Support Care Cancer, 2016 Oct 14; 25(2). PMID: 27734153
Compatibility of Biosimilar Filgrastim with Cytotoxic Chemotherapy during the Treatment of Malignant Diseases (VENICE): A Prospective, Multicenter, Non-Interventional, Longitudinal Study.
Stefan Fruehauf, Burkhard Otremba, Oliver Stötzer, Christine Rudolph.
Adv Ther, 2016 Oct 28; 33(11). PMID: 27743353    Free PMC article.
A phase III, randomized, non-inferiority study comparing the efficacy and safety of biosimilar filgrastim versus originator filgrastim for chemotherapy-induced neutropenia in breast cancer patients.
Roberto Hegg, André Mattar, +5 authors, Sylvie van-Eyll-Rocha.
Clinics (Sao Paulo), 2016 Oct 21; 71(10). PMID: 27759847    Free PMC article.
Pegfilgrastim in primary prophylaxis of febrile neutropenia following frontline bendamustine plus rituximab treatment in patients with indolent non-Hodgkin lymphoma: a single center, real-life experience.
Claudio Cerchione, Amalia De Renzo, +5 authors, Marco Picardi.
Support Care Cancer, 2016 Nov 05; 25(3). PMID: 27812763    Free PMC article.
Patterns of growth factor usage and febrile neutropenia among older patients with diffuse large B-cell non-Hodgkin lymphoma treated with CHOP or R-CHOP: the Intergroup experience (CALGB 9793; ECOG-SWOG 4494).
Vicki A Morrison, Edie A Weller, +4 authors, Bruce A Peterson.
Leuk Lymphoma, 2016 Dec 15; 58(8). PMID: 27967294    Free PMC article.
Drug-Induced Neutropenia: A Focus on Rituximab-Induced Late-Onset Neutropenia.
Donald C Moore.
P T, 2016 Dec 19; 41(12). PMID: 27990078    Free PMC article.
Safety of Same-day Pegfilgrastim Administration in Metastatic Castration-resistant Prostate Cancer Treated With Cabazitaxel With or Without Carboplatin.
Mehmet Asim Bilen, Diana H Cauley, +7 authors, Jeri Kim.
Clin Genitourin Cancer, 2017 Jan 01; 15(3). PMID: 28038931    Free PMC article.
Interstitial pneumonia following administration of pegfilgrastim during carboplatin and etoposide chemotherapy for small-cell lung cancer.
Masayuki Shirasawa, Yoshiro Nakahara, +7 authors, Noriyuki Masuda.
Mol Clin Oncol, 2017 Jan 21; 5(6). PMID: 28105350    Free PMC article.
Evaluation of a biosimilar granulocyte colony-stimulating factor (filgrastim XM02) for peripheral blood stem cell mobilization and transplantation: a single center experience in Japan.
Hideaki Yoshimura, Masaaki Hotta, +6 authors, Shosaku Nomura.
J Blood Med, 2017 Feb 10; 8. PMID: 28182150    Free PMC article.
Prophylactic Measures During Induction for Acute Myeloid Leukemia.
Matthew W McCarthy, Thomas J Walsh.
Curr Oncol Rep, 2017 Mar 03; 19(3). PMID: 28251490
Impact of Abbreviated Filgrastim Schedule on Survival and Hematopoietic Recovery after Irradiation in Four Mouse Strains with Different Radiosensitivity.
Merriline Satyamitra, Vidya P Kumar, +4 authors, Sanchita P Ghosh.
Radiat Res, 2017 Apr 01; 187(6). PMID: 28362168    Free PMC article.
Hospitalizations, outcomes, and management costs of febrile neutropenia in patients from a managed care population.
Aniket A Kawatkar, Albert J Farias, +4 authors, David B Chandler.
Support Care Cancer, 2017 Apr 12; 25(9). PMID: 28397022    Free PMC article.
The development of a prediction tool to identify cancer patients at high risk for chemotherapy-induced nausea and vomiting.
G Dranitsaris, A Molassiotis, +6 authors, M Aapro.
Ann Oncol, 2017 Apr 12; 28(6). PMID: 28398530    Free PMC article.
Cost of Cancer-Related Neutropenia or Fever Hospitalizations, United States, 2012.
Eric Tai, Gery P Guy, Angela Dunbar, Lisa C Richardson.
J Oncol Pract, 2017 Apr 25; 13(6). PMID: 28437150    Free PMC article.
Use of prophylactic growth factors and antimicrobials in elderly patients with cancer: a review of the Medicare database.
Romina Sosa, Shuling Li, +3 authors, Allan J Collins.
Support Care Cancer, 2017 May 01; 25(10). PMID: 28456908
[Choosing wisely recommendations in hematology and oncology].
S W Krause, A Neubauer.
Internist (Berl), 2017 May 13; 58(6). PMID: 28497377
Neoadjuvant chemotherapy with trastuzumab, docetaxel, and carboplatin administered every 3 weeks for Japanese women with HER2-positive primary breast cancer: efficacy and safety.
Ikuko Sugitani, Shigeto Ueda, +11 authors, Toshiaki Saeki.
Int J Clin Oncol, 2017 May 27; 22(5). PMID: 28547525    Free PMC article.
Condensed versus standard schedule of high-dose cytarabine consolidation therapy with pegfilgrastim growth factor support in acute myeloid leukemia.
S Jaramillo, A Benner, +30 authors, R F Schlenk.
Blood Cancer J, 2017 May 27; 7(5). PMID: 28548643    Free PMC article.
Incidence and risk factors of febrile neutropenia in patients with non-Hodgkin B-cell lymphoma receiving R-CHOP in a single center in Japan.
Masahiro Yokoyama, Yoshiharu Kusano, +8 authors, Kiyohiko Hatake.
Support Care Cancer, 2017 May 30; 25(11). PMID: 28551843    Free PMC article.
Evaluation of the safety and immunomodulatory effects of sargramostim in a randomized, double-blind phase 1 clinical Parkinson's disease trial.
Howard E Gendelman, Yuning Zhang, +16 authors, R Lee Mosley.
NPJ Parkinsons Dis, 2017 Jun 27; 3. PMID: 28649610    Free PMC article.
Capecitabine, Oxaliplatin, and Bevacizumab (BCapOx) Regimen for Metastatic Colorectal Cancer.
Meghan J Garrett, J Aubrey Waddell, Dominic A Solimando.
Hosp Pharm, 2017 Aug 15; 52(5). PMID: 28804149    Free PMC article.
Docetaxel versus docetaxel plus cisplatin for non-small-cell lung cancer: a meta-analysis of randomized clinical trials.
Ang Li, Zhi-Jian Wei, +4 authors, Shi-Qing Feng.
Oncotarget, 2017 Sep 17; 8(34). PMID: 28915677    Free PMC article.
Time trends in utilization of G-CSF prophylaxis and risk of febrile neutropenia in a Medicare population receiving adjuvant chemotherapy for early-stage breast cancer.
Ravi K Goyal, Spiros Tzivelekis, +2 authors, James A Kaye.
Support Care Cancer, 2017 Sep 19; 26(2). PMID: 28921379
Clinical equivalence with G-CSF biosimilars: methodologic approach in a (neo)adjuvant setting in non-metastatic breast cancer.
A Krendyukov, M Schiestl, N Höbel, M Aapro.
Support Care Cancer, 2017 Sep 21; 26(1). PMID: 28929372    Free PMC article.
1-Pamitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol May Reduce Incidence of Gemcitabine-Induced Neutropenia: A Pilot Case-Controlled Study.
Dongwook Oh, Myung-Hwan Kim, +7 authors, Jae Wha Kim.
World J Oncol, 2015 Aug 01; 6(4). PMID: 28983339    Free PMC article.
Pharmacokinetics of carfilzomib in patients with advanced malignancies and varying degrees of hepatic impairment: an open-label, single-arm, phase 1 study.
Jennifer Brown, Ruth Plummer, +7 authors, Ulka Vaishampayan.
Exp Hematol Oncol, 2017 Oct 14; 6. PMID: 29026685    Free PMC article.
The risk of febrile neutropenia in breast cancer patients following adjuvant chemotherapy is predicted by the time course of interleukin-6 and C-reactive protein by modelling.
Ida Netterberg, Mats O Karlsson, +3 authors, Lena E Friberg.
Br J Clin Pharmacol, 2017 Nov 28; 84(3). PMID: 29178353    Free PMC article.
Safety Profile of Biosimilar Filgrastim (Zarzio/Zarxio): A Combined Analysis of Phase III Studies.
Nadia Harbeck, Pere Gascón, +3 authors, Kimberly Blackwell.
Oncologist, 2018 Jan 11; 23(4). PMID: 29317553    Free PMC article.
Whom to treat? Factors associated with chemotherapy recommendations and outcomes among patients with NHL at the Uganda Cancer Institute.
Manoj Menon, Anna Coghill, +5 authors, Corey Casper.
PLoS One, 2018 Feb 02; 13(2). PMID: 29389998    Free PMC article.
Filgrastim use in patients receiving chemotherapy for early-stage breast cancer-a survey of physicians and patients.
John Hilton, Lisa Vandermeer, +8 authors, Mark Clemons.
Support Care Cancer, 2018 Feb 08; 26(7). PMID: 29411131
Medication overuse in oncology: current trends and future implications for patients and society.
Stephen M Schleicher, Peter B Bach, Konstantina Matsoukas, Deborah Korenstein.
Lancet Oncol, 2018 Apr 04; 19(4). PMID: 29611528    Free PMC article.
The prognostic impact of abdominal surgery in cancer patients with neutropenic enterocolitis: a systematic review and meta-analysis, on behalf the Groupe de Recherche en Réanimation Respiratoire du patient d'Onco-Hématologie (GRRR-OH).
Colombe Saillard, Lara Zafrani, +9 authors, Djamel Mokart.
Ann Intensive Care, 2018 Apr 21; 8(1). PMID: 29675758    Free PMC article.
Pretreatment monocyte counts and neutrophil counts predict the risk for febrile neutropenia in patients undergoing TPF chemotherapy for head and neck squamous cell carcinoma.
Marie Shimanuki, Yorihisa Imanishi, +19 authors, Kaoru Ogawa.
Oncotarget, 2018 May 04; 9(27). PMID: 29721176    Free PMC article.
A comparison of the effect of xinruibai versus filgrastim on hematopoietic reconstruction after allogeneic hematopoietic stem cell transplantation.
Qixiang Ye, Hebi Jiang, Hua Jiang.
Ital J Pediatr, 2018 Jun 02; 44(1). PMID: 29855330    Free PMC article.
Febrile neutropenia in adjuvant and neoadjuvant chemotherapy for breast cancer: a retrospective study in routine clinical practice from a single institution.
Joy Bacrie, Marc Laurans, +9 authors, Delphine Lefeuvre.
Support Care Cancer, 2018 Jun 02; 26(12). PMID: 29855772
Docetaxel plus ramucirumab with primary prophylactic pegylated-granulocyte-colony stimulating factor for pretreated non-small cell lung cancer.
Akito Hata, Daijiro Harada, +6 authors, Nobuyuki Katakami.
Oncotarget, 2018 Jul 03; 9(45). PMID: 29963237    Free PMC article.
Is There a Role for Hematopoietic Growth Factors During Sepsis?
Benjamin G Chousterman, Marine Arnaud.
Front Immunol, 2018 Jul 07; 9. PMID: 29977234    Free PMC article.
Lenalidomide consolidation benefits patients with CLL receiving chemoimmunotherapy: results for CALGB 10404 (Alliance).
John C Byrd, Amy S Ruppert, +14 authors, Richard A Larson.
Blood Adv, 2018 Jul 22; 2(14). PMID: 30030269    Free PMC article.
Immunomodulation as Therapy for Fungal Infection: Are We Closer?
Qi Hui Sam, Wen Shan Yew, +2 authors, Louis Yi Ann Chai.
Front Microbiol, 2018 Aug 10; 9. PMID: 30090091    Free PMC article.
Incidence of febrile neutropenia during chemotherapy among patients with nonmyeloid cancer receiving filgrastim vs a filgrastim biosimilar.
Lee S Schwartzberg, Lincy S Lal, +4 authors, Stephanie Korrer.
Clinicoecon Outcomes Res, 2018 Sep 15; 10. PMID: 30214262    Free PMC article.
Home administration of filgrastim (Nivestim™) in primary prophylaxis of chemotherapy-induced febrile neutropenia.
Burkhard Otremba, Carsten Hielscher, Volker Petersen, Christian Petrik.
Patient Prefer Adherence, 2018 Nov 10; 12. PMID: 30410313    Free PMC article.
Oncologic Emergencies-The Old, the New, and the Deadly.
Krishna Thandra, Zuhair Salah, Sanjay Chawla.
J Intensive Care Med, 2018 Nov 10; 35(1). PMID: 30411648    Free PMC article.
Elective nodal irradiation or involved-field irradiation in definitive chemoradiotherapy for esophageal squamous cell cancer: a retrospective analysis in clinical N0 patients.
Y Sun, X L Zhang, +3 authors, M H Li.
Curr Oncol, 2018 Nov 23; 25(5). PMID: 30464693    Free PMC article.
Filgrastim prophylaxis in elderly cancer patients in the real-life setting: a French multicenter observational study, the TULIP study.
Kamel Laribi, Delphine Badinand, +5 authors, Rafik Diab.
Support Care Cancer, 2019 Mar 16; 27(11). PMID: 30874925    Free PMC article.
Strategies to generate functionally normal neutrophils to reduce infection and infection-related mortality in cancer chemotherapy.
Hisham Abdel-Azim, Weili Sun, Lingtao Wu.
Pharmacol Ther, 2019 Aug 31; 204. PMID: 31470030    Free PMC article.
Efficacy and tolerability of granulocyte colony-stimulating factors in cancer patients after chemotherapy: A systematic review and Bayesian network meta-analysis.
Yong Wang, Lin Chen, +4 authors, Yong Li.
Sci Rep, 2019 Oct 28; 9(1). PMID: 31653961    Free PMC article.
Systematic Review.
A multicenter prospective study of 515 febrile neutropenia episodes in Argentina during a 5-year period.
Roberto L Parodi, Mariana Lagrutta, +7 authors, Alcides A Greca.
PLoS One, 2019 Nov 02; 14(10). PMID: 31671108    Free PMC article.
Granulocyte-Colony-Stimulating Factor Effectively Shortens Recovery Duration in Anti-Thyroid-Drug-Induced Agranulocytosis: A Systematic Review and Meta-Analysis.
Yonghui Wang, Xiaoying Li, +5 authors, Bingbing Zha.
Front Endocrinol (Lausanne), 2019 Dec 12; 10. PMID: 31824417    Free PMC article.
Systematic Review.
Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): overall survival and updated results of a randomised, double-blind, phase 3 trial.
Daniel P Petrylak, Ronald de Wit, +43 authors, RANGE study investigators.
Lancet Oncol, 2019 Nov 23; 21(1). PMID: 31753727    Free PMC article.
Myelodysplastic syndrome and acute myeloid leukemia after receipt of granulocyte colony-stimulating factors in older patients with non-Hodgkin lymphoma.
Gregory S Calip, Kellyn M Moran, +7 authors, Brian C-H Chiu.
Cancer, 2018 Dec 15; 125(7). PMID: 30548485    Free PMC article.
A multi-national, randomised, open-label, parallel, phase III non-inferiority study comparing NK105 and paclitaxel in metastatic or recurrent breast cancer patients.
Yasuhiro Fujiwara, Hirofumi Mukai, +14 authors, Yoshihiro Nambu.
Br J Cancer, 2019 Feb 13; 120(5). PMID: 30745582    Free PMC article.
Clinical significance of primary prophylactic pegylated-granulocyte-colony stimulating factor after the administration of ramucirumab plus docetaxel in patients with previously treated non-small cell lung cancer.
Atsuto Mouri, Kyoichi Kaira, +4 authors, Hiroshi Kagamu.
Thorac Cancer, 2019 Mar 13; 10(4). PMID: 30859745    Free PMC article.
Front-Line Treatment of High Grade B Cell Non-Hodgkin Lymphoma.
Murali Kesavan, Toby A Eyre, Graham P Collins.
Curr Hematol Malig Rep, 2019 Jun 30; 14(4). PMID: 31254155    Free PMC article.
Granulopoiesis-stimulating factors to prevent adverse effects in the treatment of malignant lymphoma.
Julia Bohlius, Christine Herbst, +2 authors, Andreas Engert.
Cochrane Database Syst Rev, 2008 Oct 10; (4). PMID: 18843642    Free PMC article.
Systematic Review.
A phase II clinical study of 13-deoxy, 5-iminodoxorubicin (GPX-150) with metastatic and unresectable soft tissue sarcoma.
Brian A Van Tine, Mark Agulnik, +5 authors, Mohammed M Milhem.
Cancer Med, 2019 Apr 25; 8(6). PMID: 31016866    Free PMC article.
Clinical utility of polyethylene glycol conjugated granulocyte colony-stimulating factor (PEG-G-CSF) for preventing severe neutropenia in metastatic colorectal cancer patients treated with FOLFOXIRI plus bevacizumab: a single-center retrospective study.
Yusuke Kitagawa, Hiroki Osumi, +10 authors, Kensei Yamaguchi.
BMC Cancer, 2020 Apr 30; 20(1). PMID: 32345249    Free PMC article.
Neutropenic Enterocolitis in the Treatment of Solid Tumors: A Case Report and Review of the Literature.
Sara Cherri, Tiziana Prochilo, +4 authors, Alberto Zaniboni.
Case Rep Oncol, 2020 May 14; 13(1). PMID: 32399014    Free PMC article.
Chemoradiation and granulocyte-colony or granulocyte macrophage-colony stimulating factors (G-CSF or GM-CSF): time to think out of the box?
Marouan Benna, Jean-Baptiste Guy, +10 authors, Alexis Vallard.
Br J Radiol, 2020 Jan 24; 93(1109). PMID: 31971824    Free PMC article.
Colony-stimulating factors for prevention and treatment of infectious complications in patients with acute myelogenous leukemia.
Ronit Gurion, Yulia Belnik-Plitman, +5 authors, Pia Raanani.
Cochrane Database Syst Rev, 2012 Jun 15; (6). PMID: 22696376    Free PMC article.
Systematic Review.
Intensive consolidation with G-CSF support: Tolerability, safety, reduced hospitalization, and efficacy in acute myeloid leukemia patients ≥60 years.
Wolfgang R Sperr, Susanne Herndlhofer, +13 authors, Peter Valent.
Am J Hematol, 2017 Jul 13; 92(10). PMID: 28699225    Free PMC article.
Immunomodulation as a Therapy for Aspergillus Infection: Current Status and Future Perspectives.
Chris D Lauruschkat, Hermann Einsele, Juergen Loeffler.
J Fungi (Basel), 2018 Dec 19; 4(4). PMID: 30558125    Free PMC article.
Lenograstim and filgrastim in the febrile neutropenia prophylaxis of hospitalized patients: efficacy and cost of the prophylaxis in a retrospective survey.
Rolando Innocenti, Luigi Rigacci, +9 authors, Alberto Bosi.
J Blood Med, 2019 Jan 16; 10. PMID: 30643475    Free PMC article.
Pegfilgrastim: More Cost Effective and Equally Efficacious Option as Compared to Filgrastim in Autologous Stem Cell Transplant.
V Sheth, A Gore, +2 authors, T Saikia.
Indian J Hematol Blood Transfus, 2019 Mar 05; 35(1). PMID: 30828150    Free PMC article.
Clinical Impact of Primary Prophylactic Pegfilgrastim in Breast Cancer Patients Receiving Adjuvant Docetaxel-Doxorubicin-Cyclophosphamide Chemotherapy.
Ye Won Jeon, Seung Taek Lim, +2 authors, Young Jin Suh.
J Breast Cancer, 2020 Nov 07; 23(5). PMID: 33154827    Free PMC article.
Use of white blood cell growth factors and risk of acute myeloid leukemia or myelodysplastic syndrome among elderly patients with non-Hodgkin lymphoma.
Stephen K Gruschkus, David Lairson, +2 authors, Xianglin L Du.
Cancer, 2010 Jul 29; 116(22). PMID: 20665502    Free PMC article.
Comparative effectiveness of white blood cell growth factors on neutropenia, infection, and survival in older people with non-Hodgkin's lymphoma treated with chemotherapy.
Stephen K Gruschkus, David Lairson, +2 authors, Xianglin L Du.
J Am Geriatr Soc, 2010 Sep 16; 58(10). PMID: 20840455    Free PMC article.
Neutropenic sepsis: management and complications.
Rachel T Clarke, Tom Jenyon, Victoria van Hamel Parsons, Andrew J King.
Clin Med (Lond), 2013 May 18; 13(2). PMID: 23681870    Free PMC article.
SEOM clinical practice guideline: management and prevention of febrile neutropenia in adults with solid tumors (2018).
A Carmona-Bayonas, P Jimenez-Fonseca, +7 authors, F Ayala de la Peña.
Clin Transl Oncol, 2018 Nov 25; 21(1). PMID: 30470991    Free PMC article.
Efficacy and safety of RGB-02, a pegfilgrastim biosimilar to prevent chemotherapy-induced neutropenia: results of a randomized, double-blind phase III clinical study vs. reference pegfilgrastim in patients with breast cancer receiving chemotherapy.
Zsuzsanna Kahan, Daniela Grecea, +6 authors, Ildiko Aradi.
BMC Cancer, 2019 Feb 08; 19(1). PMID: 30727980    Free PMC article.
Bone Marrow and Peripheral Blood Cells Toxicity of a Single 2.0 Gy Cobalt60 Ionizing Radiation: An Animal Model.
Shittu Akeem, Olatunbosun Lukman, +3 authors, Omokanye Khadijat.
Ethiop J Health Sci, 2019 Apr 24; 29(2). PMID: 31011267    Free PMC article.
A Novel Methanol-Free Platform for Extracellular Expression of rhGM-CSF in Pichia pastoris.
Roghayeh Shirvani, Sajjad Yazdanpanah, Mohammad Barshan-Tashnizi, Maryam Shahali.
Mol Biotechnol, 2019 May 06; 61(7). PMID: 31054084
Use and effectiveness of pegfilgrastim prophylaxis in US clinical practice:a retrospective observational study.
Derek Weycker, Robin Doroff, +6 authors, Gary H Lyman.
BMC Cancer, 2019 Aug 11; 19(1). PMID: 31399079    Free PMC article.
Impact of granulocyte colony-stimulating factor on FOLFIRINOX-induced neutropenia prevention: A population pharmacokinetic/pharmacodynamic approach.
Pauline Macaire, Justine Paris, +3 authors, Antonin Schmitt.
Br J Clin Pharmacol, 2020 May 10; 86(12). PMID: 32386071    Free PMC article.
A Three-Arm Randomized Phase II Study of Bendamustine/Rituximab with Bortezomib Induction or Lenalidomide Continuation in Untreated Follicular Lymphoma: ECOG-ACRIN E2408.
Andrew M Evens, Fangxin Hong, +13 authors, Brad S Kahl.
Clin Cancer Res, 2020 Jun 14; 26(17). PMID: 32532790    Free PMC article.
Change in Body Weight and Serum Albumin Levels in Febrile Neutropenic Lung Cancer Patients.
Naomi Kayauchi, Yumi Nakagawa, +2 authors, Hiroaki Satoh.
Asian Pac Isl Nurs J, 2020 Dec 17; 5(3). PMID: 33324729    Free PMC article.
Emerging therapies in Parkinson disease - repurposed drugs and new approaches.
Ahmad Elkouzi, Vinata Vedam-Mai, Robert S Eisinger, Michael S Okun.
Nat Rev Neurol, 2019 Mar 15; 15(4). PMID: 30867588    Free PMC article.
A Novel PCR Method for Detecting ACE Gene Insertion/Deletion Polymorphisms and its Clinical Application.
Xue-Min Yang, Jian-Ping Liang, +5 authors, Wen-Li Hui.
Biol Proced Online, 2021 Jan 09; 23(1). PMID: 33413084    Free PMC article.
Sustained release of active chemotherapeutics from injectable-solid β-hairpin peptide hydrogel.
Jessie E P Sun, Brandon Stewart, +4 authors, Darrin J Pochan.
Biomater Sci, 2016 Feb 26; 4(5). PMID: 26906463    Free PMC article.
Critically Ill Pediatric Oncology Patients: What the Intensivist Needs to Know? Pediatric Critical Care Medicine.
Amin Al Haj Moussa, Ata Ur Rehman Maaz, Nesreen Faqih, Manu Sundaram.
Indian J Crit Care Med, 2021 Jan 16; 24(12). PMID: 33446982    Free PMC article.
Risk of chemotherapy-induced febrile neutropenia in patients with metastatic cancer not receiving granulocyte colony-stimulating factor prophylaxis in US clinical practice.
Ahuva Averin, Amanda Silvia, +8 authors, Derek Weycker.
Support Care Cancer, 2020 Sep 04; 29(4). PMID: 32880732    Free PMC article.
Randomized and dose-escalation trials of recombinant human serum albumin /granulocyte colony-stimulating factor in patients with breast cancer receiving anthracycline-containing chemotherapy.
Shanshan Chen, Yiqun Han, +15 authors, Binghe Xu.
BMC Cancer, 2021 Apr 02; 21(1). PMID: 33789616    Free PMC article.
Maternal and Neonatal Outcome after the Use of G-CSF for Cancer Treatment during Pregnancy.
Claudia Berends, Charlotte Maggen, +9 authors, Frédéric Amant.
Cancers (Basel), 2021 Apr 04; 13(6). PMID: 33802196    Free PMC article.
Four Cycles of Etoposide plus Cisplatin for Patients with Good-Risk Advanced Germ Cell Tumors.
Samuel A Funt, Deaglan J McHugh, +13 authors, Darren R Feldman.
Oncologist, 2021 Feb 16; 26(6). PMID: 33586274    Free PMC article.