. 2007 Apr;8(3).
doi: 10.1007/s11154-007-9035-3.

Molecular profiling in breast cancer

Shannon R Morris 1 Lisa A Carey  
  • PMID: 17464566
  •     77 References
  •     16 citations


Molecular profiling has provided biological evidence for the heterogeneity of breast cancer through the identification of intrinsic subtypes like Luminal A, Luminal B, HER2+/ER- and basal-like. It has also led to the development of clinically applicable gene expression-based prognostic panels like the Mammaprint and Oncotype Dx. The increasingly sophisticated understanding allowed by this and similar technology promises future individualized therapy.

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