Journal Article
. 2007 Nov;357(21).
doi: 10.1056/NEJMsr077003.

Statistics in medicine--reporting of subgroup analyses in clinical trials

Rui Wang  Stephen W Lagakos  James H Ware  David J Hunter  Jeffrey M Drazen  
  • PMID: 18032770
  •     329 citations

No abstract available

The Lipid lowering and Onset of Renal Disease (LORD) Trial: a randomized double blind placebo controlled trial assessing the effect of atorvastatin on the progression of kidney disease.
Robert G Fassett, Madeleine J Ball, +2 authors, Jeff S Coombes.
BMC Nephrol, 2008 Mar 28; 9. PMID: 18366658    Free PMC article.
Reducing the probability of false positive research findings by pre-publication validation - experience with a large multiple sclerosis database.
Martin Daumer, Ulrike Held, +3 authors, George Ebers.
BMC Med Res Methodol, 2008 Apr 12; 8. PMID: 18402689    Free PMC article.
How to interpret figures in reports of clinical trials.
Stuart J Pocock, Thomas G Travison, Lisa M Wruck.
BMJ, 2008 May 24; 336(7654). PMID: 18497415    Free PMC article.
Review.
Sentinel node mapping during laparoscopic distal gastrectomy for gastric cancer.
Emanuel Sporn, J Wade Davis, Klaus Thaler, Brent W Miedema.
Surg Endosc, 2008 Jun 17; 22(9). PMID: 18553200
Ambulatory continuous posterior lumbar plexus nerve blocks after hip arthroplasty: a dual-center, randomized, triple-masked, placebo-controlled trial.
Brian M Ilfeld, Scott T Ball, +9 authors, R Scott Meyer.
Anesthesiology, 2008 Aug 23; 109(3). PMID: 18719448    Free PMC article.
Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial.
Stanley J Szefler, Herman Mitchell, +14 authors, William W Busse.
Lancet, 2008 Sep 23; 372(9643). PMID: 18805335    Free PMC article.
Stratification for spontaneous report databases.
Stephen J W Evans.
Drug Saf, 2008 Oct 09; 31(11). PMID: 18840024
Flaws in the U.S. Food and Drug Administration's rationale for supporting the development and approval of BiDil as a treatment for heart failure only in black patients.
George T H Ellison, Jay S Kaufman, +2 authors, Jonathan D Kahn.
J Law Med Ethics, 2008 Oct 09; 36(3). PMID: 18840235    Free PMC article.
Toll-like receptor 4 polymorphisms and aspergillosis in stem-cell transplantation.
Pierre-Yves Bochud, Jason W Chien, +9 authors, Michael Boeckh.
N Engl J Med, 2008 Oct 24; 359(17). PMID: 18946062    Free PMC article.
Highly Cited.
Aggressive vs. conservative phototherapy for infants with extremely low birth weight.
Brenda H Morris, William Oh, +28 authors, NICHD Neonatal Research Network.
N Engl J Med, 2008 Oct 31; 359(18). PMID: 18971491    Free PMC article.
Predicting successful treatment outcome of web-based self-help for problem drinkers: secondary analysis from a randomized controlled trial.
Heleen Riper, Jeannet Kramer, +3 authors, Pim Cuijpers.
J Med Internet Res, 2008 Nov 27; 10(4). PMID: 19033150    Free PMC article.
Prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon.
Adrian M Di Bisceglie, Mitchell L Shiffman, +12 authors, HALT-C Trial Investigators.
N Engl J Med, 2008 Dec 05; 359(23). PMID: 19052125    Free PMC article.
Highly Cited.
Age-related crossover in breast cancer incidence rates between black and white ethnic groups.
William F Anderson, Philip S Rosenberg, +2 authors, Ruth M Pfeiffer.
J Natl Cancer Inst, 2008 Dec 11; 100(24). PMID: 19066264    Free PMC article.
Dry-weight reduction in hypertensive hemodialysis patients (DRIP): a randomized, controlled trial.
Rajiv Agarwal, Pooneh Alborzi, Sangeetha Satyan, Robert P Light.
Hypertension, 2009 Jan 21; 53(3). PMID: 19153263    Free PMC article.
A small sample study of the STEPP approach to assessing treatment-covariate interactions in survival data.
Marco Bonetti, David Zahrieh, Bernard F Cole, Richard D Gelber.
Stat Med, 2009 Jan 27; 28(8). PMID: 19170050    Free PMC article.
The inclusion of women and minorities in smoking cessation clinical trials: a systematic review.
Daniel L Dickerson, Robert F Leeman, Carolyn M Mazure, Stephanie S O'Malley.
Am J Addict, 2009 Feb 17; 18(1). PMID: 19219662    Free PMC article.
Systematic Review.
The efficacy of natalizumab in patients with relapsing multiple sclerosis: subgroup analyses of AFFIRM and SENTINEL.
Michael Hutchinson, Ludwig Kappos, +18 authors, AFFIRM and SENTINEL Investigators.
J Neurol, 2009 Mar 25; 256(3). PMID: 19308305
How to guarantee finding a statistically significant difference: the use and abuse of subgroup analyses.
Peter M Fayers, Madeleine T King.
Qual Life Res, 2009 Apr 04; 18(5). PMID: 19343540
The role of genetics in susceptibility to diabetic retinopathy.
Gerald Liew, Ronald Klein, Tien Y Wong.
Int Ophthalmol Clin, 2009 Apr 08; 49(2). PMID: 19349785    Free PMC article.
Review.
Corticosteroids in peri-radicular infiltration for radicular pain: a randomised double blind controlled trial. One year results and subgroup analysis.
Suhayl Tafazal, Leslie Ng, Neeraj Chaudhary, Philip Sell.
Eur Spine J, 2009 Apr 24; 18(8). PMID: 19387704    Free PMC article.
Outcome based subgroup analysis: a neglected concern.
Karim F Hirji, Morten W Fagerland.
Trials, 2009 May 21; 10. PMID: 19454041    Free PMC article.
Repeated ethanol exposure affects the acquisition of spatial memory in adolescent female rats.
Ratna Sircar, Ashim K Basak, Debashish Sircar.
Behav Brain Res, 2009 May 26; 202(2). PMID: 19463705    Free PMC article.
Evaluating erythropoietin-associated tumor progression using archival tissues from a phase III clinical trial.
Chris P Miller, Kimberly A Lowe, +5 authors, C Anthony Blau.
Stem Cells, 2009 Jun 23; 27(9). PMID: 19544471    Free PMC article.
Dealing with heterogeneity of treatment effects: is the literature up to the challenge?
Nicole B Gabler, Naihua Duan, +3 authors, Richard L Kravitz.
Trials, 2009 Jun 24; 10. PMID: 19545379    Free PMC article.
Effect of once-yearly zoledronic acid five milligrams on fracture risk and change in femoral neck bone mineral density.
Richard Eastell, Dennis M Black, +9 authors, HORIZON Pivotal Fracture Trial.
J Clin Endocrinol Metab, 2009 Jul 02; 94(9). PMID: 19567517    Free PMC article.
Synchronized nasal intermittent positive-pressure ventilation and neonatal outcomes.
Vineet Bhandari, Neil N Finer, +6 authors, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.
Pediatrics, 2009 Aug 05; 124(2). PMID: 19651577    Free PMC article.
Letrozole therapy alone or in sequence with tamoxifen in women with breast cancer.
BIG 1-98 Collaborative Group, Henning Mouridsen, +10 authors, Alan S Coates.
N Engl J Med, 2009 Aug 21; 361(8). PMID: 19692688    Free PMC article.
Highly Cited.
The Gini concentration test for survival data.
Marco Bonetti, Chiara Gigliarano, Pietro Muliere.
Lifetime Data Anal, 2009 Sep 04; 15(4). PMID: 19728088
Prospective meta-analysis using individual patient data in intensive care medicine.
Michael C Reade, Anthony Delaney, +6 authors, Derek C Angus.
Intensive Care Med, 2009 Sep 18; 36(1). PMID: 19760395    Free PMC article.
Qualitative age interactions in breast cancer studies: mind the gap.
William F Anderson, Ismail Jatoi, Mark E Sherman.
J Clin Oncol, 2009 Oct 15; 27(32). PMID: 19826117    Free PMC article.
Effects of exercise on mobility in obese and nonobese older adults.
Todd M Manini, Anne B Newman, +11 authors, LIFE Research Group.
Obesity (Silver Spring), 2009 Oct 17; 18(6). PMID: 19834467    Free PMC article.
Subgroup Analysis of Trials Is Rarely Easy (SATIRE): a study protocol for a systematic review to characterize the analysis, reporting, and claim of subgroup effects in randomized trials.
Xin Sun, Matthias Briel, +20 authors, Gordon H Guyatt.
Trials, 2009 Nov 11; 10. PMID: 19900273    Free PMC article.
Assessing Heterogeneity of Treatment Effects: Are Authors Misinterpreting Their Results?
Erik Fernandez Y Garcia, Hien Nguyen, +2 authors, Richard L Kravitz.
Health Serv Res, 2009 Nov 26; 45(1). PMID: 19929962    Free PMC article.
Carotid endarterectomy benefits patients with CKD and symptomatic high-grade stenosis.
Anna Mathew, Michael Eliasziw, +4 authors, North American Symptomatic Carotid Endarterectomy Trial (NASCET) Collaborators.
J Am Soc Nephrol, 2009 Dec 17; 21(1). PMID: 20007752    Free PMC article.
Interpreting results in 2 x 2 tables: part 9 of a series on evaluation of scientific publications.
Wilhelm Sauerbrei, Maria Blettner.
Dtsch Arztebl Int, 2009 Dec 30; 106(48). PMID: 20038982    Free PMC article.
Review.
Long-term efficacy and safety of Raltegravir combined with optimized background therapy in treatment-experienced patients with drug-resistant HIV infection: week 96 results of the BENCHMRK 1 and 2 Phase III trials.
Roy T Steigbigel, David A Cooper, +20 authors, BENCHMRK Study Teamsa.
Clin Infect Dis, 2010 Jan 21; 50(4). PMID: 20085491    Free PMC article.
Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer.
Philip W Kantoff, Thomas J Schuetz, +11 authors, Wayne R Godfrey.
J Clin Oncol, 2010 Jan 27; 28(7). PMID: 20100959    Free PMC article.
Highly Cited.
Effect of intensive compared with standard glycemia treatment strategies on mortality by baseline subgroup characteristics: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.
Jorge Calles-Escandón, Laura C Lovato, +9 authors, Bruce Hamilton.
Diabetes Care, 2010 Jan 28; 33(4). PMID: 20103550    Free PMC article.
Multiple micronutrient supplementation during pregnancy in low-income countries: a meta-analysis of effects on birth size and length of gestation.
Caroline H D Fall, David J Fisher, +2 authors, Maternal Micronutrient Supplementation Study Group.
Food Nutr Bull, 2010 Feb 04; 30(4 Suppl). PMID: 20120795    Free PMC article.
The Making of Evidence-based Practice: The Case of Project ALERT.
Dennis M Gorman, Eugenia Conde.
Child Youth Serv Rev, 2010 Feb 18; 32(2). PMID: 20161479    Free PMC article.
A school-based intervention for diabetes risk reduction.
HEALTHY Study Group, Gary D Foster, +8 authors, Kathryn Hirst.
N Engl J Med, 2010 Jun 29; 363(5). PMID: 20581420    Free PMC article.
Highly Cited.
Influence of zinc supplementation in acute diarrhea differs by the isolated organism.
Archana B Patel, Michael J Dibley, +2 authors, Hemant Kulkarni.
Int J Pediatr, 2010 Jul 02; 2010. PMID: 20592753    Free PMC article.
Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial.
Faramarz Ismail-Beigi, Timothy Craven, +21 authors, ACCORD trial group.
Lancet, 2010 Jul 03; 376(9739). PMID: 20594588    Free PMC article.
Highly Cited.
Rituximab versus cyclophosphamide for ANCA-associated vasculitis.
John H Stone, Peter A Merkel, +27 authors, RAVE-ITN Research Group.
N Engl J Med, 2010 Jul 22; 363(3). PMID: 20647199    Free PMC article.
Highly Cited.
Assessing and reporting heterogeneity in treatment effects in clinical trials: a proposal.
David M Kent, Peter M Rothwell, +2 authors, Rodney A Hayward.
Trials, 2010 Aug 14; 11. PMID: 20704705    Free PMC article.
Highly Cited.
Decision trees for identifying predictors of treatment effectiveness in clinical trials and its application to ovulation in a study of women with polycystic ovary syndrome.
Heping Zhang, Richard S Legro, +13 authors, Reproductive Medicine Network.
Hum Reprod, 2010 Aug 19; 25(10). PMID: 20716558    Free PMC article.
The effect of dietary patterns on estimated coronary heart disease risk: results from the Dietary Approaches to Stop Hypertension (DASH) trial.
Steven T Chen, Nisa M Maruthur, Lawrence J Appel.
Circ Cardiovasc Qual Outcomes, 2010 Sep 03; 3(5). PMID: 20807884    Free PMC article.
Intensive blood-pressure control in hypertensive chronic kidney disease.
Lawrence J Appel, Jackson T Wright, +28 authors, AASK Collaborative Research Group.
N Engl J Med, 2010 Sep 08; 363(10). PMID: 20818902    Free PMC article.
Highly Cited.
Evaluation of treatment-effect heterogeneity using biomarkers measured on a continuous scale: subpopulation treatment effect pattern plot.
Ann A Lazar, Bernard F Cole, Marco Bonetti, Richard D Gelber.
J Clin Oncol, 2010 Sep 15; 28(29). PMID: 20837942    Free PMC article.
Analysis of randomized comparative clinical trial data for personalized treatment selections.
Tianxi Cai, Lu Tian, Peggy H Wong, L J Wei.
Biostatistics, 2010 Sep 30; 12(2). PMID: 20876663    Free PMC article.
Point: Intensive glycemic control and mortality in ACCORD--a chance finding?
John M Lachin.
Diabetes Care, 2010 Dec 01; 33(12). PMID: 21115777    Free PMC article.
Using the systematic review methodology to evaluate factors that influence the persistence of influenza virus in environmental matrices.
C K Irwin, K J Yoon, +4 authors, A M O'Connor.
Appl Environ Microbiol, 2010 Dec 15; 77(3). PMID: 21148699    Free PMC article.
Systematic Review.
Methodological criteria for the assessment of moderators in systematic reviews of randomised controlled trials: a consensus study.
Tamar Pincus, Clare Miles, +3 authors, Stephanie J C Taylor.
BMC Med Res Methodol, 2011 Feb 02; 11. PMID: 21281501    Free PMC article.
Examining the evidence: a systematic review of the inclusion and analysis of older adults in randomized controlled trials.
Donna M Zulman, Jeremy B Sussman, +3 authors, Rodney A Hayward.
J Gen Intern Med, 2011 Feb 03; 26(7). PMID: 21286840    Free PMC article.
Highly Cited. Systematic Review.
Reporting statistics in clinical trials published in Indian journals: a survey.
Goyal Jaykaran, N D Kantharia, +2 authors, J Goyal.
Afr Health Sci, 2011 Feb 18; 10(2). PMID: 21326978    Free PMC article.
Long-term treatment with finasteride improves clinical progression of benign prostatic hyperplasia in men with an enlarged versus a smaller prostate: data from the MTOPS trial.
Steven A Kaplan, Jeannette Y Lee, +2 authors, MTOPS Research Group.
J Urol, 2011 Feb 22; 185(4). PMID: 21334655    Free PMC article.
Inclusion, analysis, and reporting of sex and race/ethnicity in clinical trials: have we made progress?
Stacie E Geller, Abby Koch, Beth Pellettieri, Molly Carnes.
J Womens Health (Larchmt), 2011 Mar 01; 20(3). PMID: 21351877    Free PMC article.
Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children.
William W Busse, Wayne J Morgan, +14 authors, Christine A Sorkness.
N Engl J Med, 2011 Mar 18; 364(11). PMID: 21410369    Free PMC article.
Highly Cited.
The (mis)use of overlap of confidence intervals to assess effect modification.
Mirjam J Knol, Wiebe R Pestman, Diederick E Grobbee.
Eur J Epidemiol, 2011 Mar 23; 26(4). PMID: 21424218    Free PMC article.
The influence of study characteristics on reporting of subgroup analyses in randomised controlled trials: systematic review.
Xin Sun, Matthias Briel, +21 authors, Gordon H Guyatt.
BMJ, 2011 Mar 30; 342. PMID: 21444636    Free PMC article.
Systematic Review.
Calcium supplements with or without vitamin D and risk of cardiovascular events: reanalysis of the Women's Health Initiative limited access dataset and meta-analysis.
Mark J Bolland, Andrew Grey, +2 authors, Ian R Reid.
BMJ, 2011 Apr 21; 342. PMID: 21505219    Free PMC article.
Highly Cited. Review.
Exploratory trials, confirmatory observations: a new reasoning model in the era of patient-centered medicine.
José A Sacristán.
BMC Med Res Methodol, 2011 Apr 27; 11. PMID: 21518440    Free PMC article.
ACE inhibition is renoprotective among obese patients with proteinuria.
Francesca Mallamaci, Piero Ruggenenti, +6 authors, REIN Study Group.
J Am Soc Nephrol, 2011 Apr 30; 22(6). PMID: 21527660    Free PMC article.
Detecting moderator effects using subgroup analyses.
Rui Wang, James H Ware.
Prev Sci, 2011 May 13; 14(2). PMID: 21562742    Free PMC article.
Interpretation of subgroup analyses in randomized trials: heterogeneity versus secondary interventions.
Tyler J VanderWeele, Mirjam J Knol.
Ann Intern Med, 2011 May 18; 154(10). PMID: 21576536    Free PMC article.
Effects of prophylactic indomethacin in extremely low-birth-weight infants with and without adequate exposure to antenatal corticosteroids.
Barbara Schmidt, Mary Seshia, +6 authors, Trial of Indomethacin Prophylaxis in Preterms Investigators.
Arch Pediatr Adolesc Med, 2011 Jul 06; 165(7). PMID: 21727276    Free PMC article.
Acupuncture in the inpatient acute care setting: a pragmatic, randomized control trial.
Jeannette Painovich, Patricia M Herman.
Evid Based Complement Alternat Med, 2011 Jul 15; 2012. PMID: 21754946    Free PMC article.
Coexistence of obstructive sleep apnoea and metabolic syndrome is independently associated with left ventricular hypertrophy and diastolic dysfunction.
Yasuhiro Usui, Yoshifumi Takata, +6 authors, Akira Yamashina.
Sleep Breath, 2011 Jul 23; 16(3). PMID: 21779756
Subgroup identification from randomized clinical trial data.
Jared C Foster, Jeremy M G Taylor, Stephen J Ruberg.
Stat Med, 2011 Aug 05; 30(24). PMID: 21815180    Free PMC article.
Highly Cited.
Pre-referral rectal artesunate in severe malaria: flawed trial.
Karim F Hirji, Zulfiqarali G Premji.
Trials, 2011 Aug 10; 12. PMID: 21824389    Free PMC article.
Randomized comparison of systemic anti-inflammatory therapy versus fluocinolone acetonide implant for intermediate, posterior, and panuveitis: the multicenter uveitis steroid treatment trial.
Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group, John H Kempen, +5 authors, Jennifer E Thorne.
Ophthalmology, 2011 Aug 16; 118(10). PMID: 21840602    Free PMC article.
Highly Cited.
Calcium and vitamin D supplements and health outcomes: a reanalysis of the Women's Health Initiative (WHI) limited-access data set.
Mark J Bolland, Andrew Grey, Greg D Gamble, Ian R Reid.
Am J Clin Nutr, 2011 Sep 02; 94(4). PMID: 21880848    Free PMC article.
Highly Cited.
The long-term impact of the MEMA kwa Vijana adolescent sexual and reproductive health intervention: effect of dose and time since intervention exposure.
Aoife M Doyle, Helen A Weiss, +6 authors, David A Ross.
PLoS One, 2011 Sep 21; 6(9). PMID: 21931861    Free PMC article.
Chemotherapy-associated thromboembolic risk in cancer outpatients and effect of nadroparin thromboprophylaxis: results of a retrospective analysis of the PROTECHT study.
Sandro Barni, Roberto Labianca, +8 authors, Giampietro Gasparini.
J Transl Med, 2011 Oct 22; 9. PMID: 22013950    Free PMC article.
Iron-fortified vs low-iron infant formula: developmental outcome at 10 years.
Betsy Lozoff, Marcela Castillo, Katy M Clark, Julia B Smith.
Arch Pediatr Adolesc Med, 2011 Nov 09; 166(3). PMID: 22064877    Free PMC article.
Adverse outcome analyses of observational data: assessing cardiovascular risk in HIV disease.
V A Triant, F Josephson, +17 authors, J Strobos.
Clin Infect Dis, 2011 Nov 19; 54(3). PMID: 22095570    Free PMC article.
Outcomes associated with matching patients' treatment preferences to physicians' recommendations: study methodology.
Nasir Umar, David Litaker, +3 authors, Darcey D Terris.
BMC Health Serv Res, 2012 Jan 05; 12. PMID: 22214259    Free PMC article.
Do we need biomarkers to predict the benefit of adding adjuvant taxanes for treatment of breast cancer?
José Pérez-García, Javier Cortés.
Breast Cancer Res, 2012 Feb 03; 14(1). PMID: 22297134    Free PMC article.
Genetic variants implicated in telomere length associated with left ventricular function in patients with hypertension and cardiac organ damage.
Matthias Huber, Andras Treszl, +9 authors, Reinhold Kreutz.
J Mol Med (Berl), 2012 Feb 09; 90(9). PMID: 22314626
Neonatal outcomes after influenza immunization during pregnancy: a randomized controlled trial.
Mark C Steinhoff, Saad B Omer, +5 authors, K Zaman.
CMAJ, 2012 Feb 23; 184(6). PMID: 22353593    Free PMC article.
Highly Cited.
Clinical trials in orthopaedics research. Part III. Overcoming operational challenges in the design and conduct of randomized clinical trials in orthopaedic surgery.
Elena Losina, James Wright, Jeffrey N Katz.
J Bone Joint Surg Am, 2012 Mar 23; 94(6). PMID: 22438008    Free PMC article.
It is not always about gains: utilities and disutilities associated with treatment features in patients with moderate-to-severe psoriasis.
Nasir Umar, Ina Schöllgen, Darcey D Terris.
Patient Prefer Adherence, 2012 Apr 27; 6. PMID: 22536054    Free PMC article.
Low-fat dairy, but not whole-/high-fat dairy, consumption is related with higher serum adiponectin levels in apparently healthy adults.
Kaijun Niu, Yoritoshi Kobayashi, +6 authors, Ryoichi Nagatomi.
Eur J Nutr, 2012 Jun 01; 52(2). PMID: 22648202
Diabetes, metformin, and breast cancer in postmenopausal women.
Rowan T Chlebowski, Anne McTiernan, +12 authors, David M Euhus.
J Clin Oncol, 2012 Jun 13; 30(23). PMID: 22689798    Free PMC article.
Angiotensin-converting enzyme inhibitor use by older adults is associated with greater functional responses to exercise.
Thomas W Buford, Todd M Manini, +7 authors, Christy S Carter.
J Am Geriatr Soc, 2012 Jun 26; 60(7). PMID: 22726232    Free PMC article.
Hidden decay of impact after education for self-management of chronic illnesses: hypotheses.
M J Park, Joseph Green, Hirono Ishikawa, Takahiro Kiuchi.
Chronic Illn, 2012 Jul 11; 9(1). PMID: 22777566    Free PMC article.
Do client attributes moderate the effectiveness of a group cognitive behavioral therapy for depression in addiction treatment?
Sarah B Hunter, Susan M Paddock, +2 authors, Kimberly A Hepner.
J Behav Health Serv Res, 2012 Jul 26; 40(1). PMID: 22828976    Free PMC article.
Changing patterns in the association between regional socio-economic context and dental caries experience according to gender and age: a multilevel study in Korean adults.
Hoo-Yeon Lee, Youn-Hee Choi, Hyoung Wook Park, Sang Gyu Lee.
Int J Health Geogr, 2012 Jul 31; 11. PMID: 22839762    Free PMC article.
A randomized controlled trial to improve health among women receiving welfare in the US: the relationship between employment outcomes and the economic recession.
Shawn M Kneipp, John A Kairalla, Amanda L Sheely.
Soc Sci Med, 2012 Sep 12; 80. PMID: 22963921    Free PMC article.
The MeTeOR trial (Meniscal Tear in Osteoarthritis Research): rationale and design features.
Jeffrey N Katz, Christine E Chaisson, +15 authors, Elena Losina.
Contemp Clin Trials, 2012 Sep 13; 33(6). PMID: 22968127    Free PMC article.
Survey finds that most meta-analysts do not attempt to collect individual patient data.
Stephanie A Kovalchik.
J Clin Epidemiol, 2012 Sep 18; 65(12). PMID: 22981246    Free PMC article.
Reporting guidelines: optimal use in preventive medicine and public health.
Karyn Popham, William A Calo, +6 authors, Patricia Dolan Mullen.
Am J Prev Med, 2012 Sep 21; 43(4). PMID: 22992369    Free PMC article.
Aggregate-data estimation of an individual patient data linear random effects meta-analysis with a patient covariate-treatment interaction term.
Stephanie A Kovalchik.
Biostatistics, 2012 Sep 25; 14(2). PMID: 23001065    Free PMC article.
N-terminal pro-B-type natriuretic peptide, left ventricular mass, and incident heart failure: Multi-Ethnic Study of Atherosclerosis.
Eui-Young Choi, Hossein Bahrami, +13 authors, Joao A C Lima.
Circ Heart Fail, 2012 Oct 04; 5(6). PMID: 23032197    Free PMC article.
Effect of a multifactorial interdisciplinary intervention on mobility-related disability in frail older people: randomised controlled trial.
Nicola Fairhall, Catherine Sherrington, +3 authors, Ian D Cameron.
BMC Med, 2012 Oct 17; 10. PMID: 23067364    Free PMC article.
Introduction to the special issue: subgroup analysis in prevention and intervention research.
Lauren H Supplee, Brendan C Kelly, +2 authors, Meryl Yoches Barofsky.
Prev Sci, 2012 Oct 24; 14(2). PMID: 23090721
Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival.
Xiaoyun Liao, Paul Lochhead, +14 authors, Shuji Ogino.
N Engl J Med, 2012 Oct 26; 367(17). PMID: 23094721    Free PMC article.
Highly Cited.
Comparative effectiveness research in heart failure therapies: women, elderly patients, and patients with kidney disease.
Rashmee U Shah, Tara I Chang, Gregg C Fonarow.
Heart Fail Clin, 2012 Nov 22; 9(1). PMID: 23168319    Free PMC article.
Review.
The effects of carbohydrate, unsaturated fat, and protein intake on measures of insulin sensitivity: results from the OmniHeart trial.
Meghana D Gadgil, Lawrence J Appel, +3 authors, Edgar R Miller.
Diabetes Care, 2012 Dec 12; 36(5). PMID: 23223345    Free PMC article.
From concepts, theory, and evidence of heterogeneity of treatment effects to methodological approaches: a primer.
Richard J Willke, Zhiyuan Zheng, +2 authors, C Daniel Mullins.
BMC Med Res Methodol, 2012 Dec 14; 12. PMID: 23234603    Free PMC article.
Review.
Sagittal plane gait characteristics in hip osteoarthritis patients with mild to moderate symptoms compared to healthy controls: a cross-sectional study.
Ingrid Eitzen, Linda Fernandes, Lars Nordsletten, May Arna Risberg.
BMC Musculoskelet Disord, 2012 Dec 22; 13. PMID: 23256709    Free PMC article.
Subgroup specific incremental value of new markers for risk prediction.
Qian M Zhou, Yingye Zheng, Tianxi Cai.
Lifetime Data Anal, 2012 Dec 25; 19(2). PMID: 23263882    Free PMC article.
Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis.
Katherine M Flegal, Brian K Kit, Heather Orpana, Barry I Graubard.
JAMA, 2013 Jan 03; 309(1). PMID: 23280227    Free PMC article.
Highly Cited. Systematic Review.
The perils of ignoring design effects in experimental studies: lessons from a mammography screening trial.
Beth A Glenn, Roshan Bastani, Annette E Maxwell.
Psychol Health, 2013 Jan 08; 28(5). PMID: 23289517    Free PMC article.
Patient-centered medicine and patient-oriented research: improving health outcomes for individual patients.
José A Sacristán.
BMC Med Inform Decis Mak, 2013 Jan 09; 13. PMID: 23294526    Free PMC article.
Influence of pharmacogenomic profiling prior to pharmaceutical treatment in metastatic colorectal cancer on cost effectiveness : a systematic review.
Martin Frank, Thomas Mittendorf.
Pharmacoeconomics, 2013 Jan 23; 31(3). PMID: 23338963
Systematic Review.
Recent development on statistical methods for personalized medicine discovery.
Yingqi Zhao, Donglin Zeng.
Front Med, 2013 Feb 05; 7(1). PMID: 23377890
Review.
Latent subgroup analysis of a randomized clinical trial through a semiparametric accelerated failure time mixture model.
L Altstein, G Li.
Biometrics, 2013 Feb 07; 69(1). PMID: 23383608    Free PMC article.
Impact of misspecifying the distribution of a prognostic factor on power and sample size for testing treatment interactions in clinical trials.
William M Reichmann, Michael P LaValley, David R Gagnon, Elena Losina.
BMC Med Res Methodol, 2013 Feb 19; 13. PMID: 23414513    Free PMC article.
Surgery versus physical therapy for a meniscal tear and osteoarthritis.
Jeffrey N Katz, Robert H Brophy, +26 authors, Elena Losina.
N Engl J Med, 2013 Mar 20; 368(18). PMID: 23506518    Free PMC article.
Highly Cited.
Safety and efficacy of duloxetine treatment in older and younger patients with osteoarthritis knee pain: a post hoc, subgroup analysis of two randomized, placebo-controlled trials.
Joseph L Micca, Dustin Ruff, Jonna Ahl, Madelaine M Wohlreich.
BMC Musculoskelet Disord, 2013 Apr 18; 14. PMID: 23590727    Free PMC article.
Physical activity, tumor PTGS2 expression, and survival in patients with colorectal cancer.
Mai Yamauchi, Paul Lochhead, +12 authors, Shuji Ogino.
Cancer Epidemiol Biomarkers Prev, 2013 May 01; 22(6). PMID: 23629521    Free PMC article.
Donepezil 23 mg: An empty suit.
David S Knopman.
Neurol Clin Pract, 2013 May 02; 2(4). PMID: 23634378    Free PMC article.
Heterogeneity of treatment effects: from "How to treat" to "Whom to treat".
Joseph R Dettori, Daniel C Norvell, Andrea C Skelly, Jens Chapman.
Evid Based Spine Care J, 2011 May 01; 2(2). PMID: 23637676    Free PMC article.
A framework for the analysis of heterogeneity of treatment effect in patient-centered outcomes research.
Ravi Varadhan, Jodi B Segal, +2 authors, Carlos O Weiss.
J Clin Epidemiol, 2013 May 09; 66(8). PMID: 23651763    Free PMC article.
Review.
Assessment of falls in older patients treated with duloxetine: a secondary analysis of a 24-week randomized, placebo-controlled trial.
J Craig Nelson, Tina M M Oakes, +5 authors, Michael J Robinson.
Prim Care Companion CNS Disord, 2013 Jun 01; 15(1). PMID: 23724353    Free PMC article.
Psychopathy as predictor and moderator of multisystemic therapy outcomes among adolescents treated for antisocial behavior.
Willeke A Manders, Maja Deković, +2 authors, Pier J M Prins.
J Abnorm Child Psychol, 2013 Jun 13; 41(7). PMID: 23756854
Predictors of stroke recurrence in patients with recent lacunar stroke and response to interventions according to risk status: secondary prevention of small subcortical strokes trial.
Robert G Hart, Lesly A Pearce, +5 authors, David C Anderson.
J Stroke Cerebrovasc Dis, 2013 Jun 27; 23(4). PMID: 23800503    Free PMC article.
A systematic review of individual patient data meta-analyses on surgical interventions.
Gerjon Hannink, Hein G Gooszen, Cornelis J H M van Laarhoven, Maroeska M Rovers.
Syst Rev, 2013 Jul 06; 2. PMID: 23826895    Free PMC article.
Systematic Review.
Treatment benefit and treatment harm rate to characterize heterogeneity in treatment effect.
Changyu Shen, Jaesik Jeong, +2 authors, Alfred Buxton.
Biometrics, 2013 Jul 20; 69(3). PMID: 23865447    Free PMC article.
Reporting characteristics of non-primary publications of results of randomized trials: a cross-sectional review.
Sally Hopewell, Gary S Collins, +4 authors, Douglas G Altman.
Trials, 2013 Aug 02; 14. PMID: 23902608    Free PMC article.
Review.
Italian guidelines on thrombolysis indications in ischemic stroke have been revised after IST-3 trial and Cochrane revision: cons.
Giorgio Costantino, Gian Marco Podda, +2 authors, Gruppo di Autoformazione Metodologica (GrAM).
Intern Emerg Med, 2013 Aug 27; 8(8). PMID: 23975391
Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial.
Aldo P Maggioni, Stephen J Greene, +10 authors, ASTRONAUT Investigators and Coordinators.
Eur Heart J, 2013 Sep 04; 34(40). PMID: 23999456    Free PMC article.
EFFECTIVELY SELECTING A TARGET POPULATION FOR A FUTURE COMPARATIVE STUDY.
Lihui Zhao, Lu Tian, +2 authors, L J Wei.
J Am Stat Assoc, 2013 Sep 24; 108(502). PMID: 24058223    Free PMC article.
The EVIDENT-trial: protocol and rationale of a multicenter randomized controlled trial testing the effectiveness of an online-based psychological intervention.
Jan Philipp Klein, Thomas Berger, +12 authors, Steffen Moritz.
BMC Psychiatry, 2013 Oct 01; 13. PMID: 24074299    Free PMC article.
The evidence for treating hypertension in older people with dementia: a systematic review.
L C Beishon, J K Harrison, +3 authors, S P Conroy.
J Hum Hypertens, 2013 Nov 08; 28(5). PMID: 24196416
Systematic Review.
New oral anticoagulants are not superior to warfarin in secondary prevention of stroke or transient ischemic attacks, but lower the risk of intracranial bleeding: insights from a meta-analysis and indirect treatment comparisons.
Partha Sardar, Saurav Chatterjee, +4 authors, Debabrata Mukherjee.
PLoS One, 2013 Nov 10; 8(10). PMID: 24204920    Free PMC article.
Systematic Review.
Once-weekly teriparatide reduces the risk of vertebral fracture in patients with various fracture risks: subgroup analysis of the Teriparatide Once-Weekly Efficacy Research (TOWER) trial.
Tetsuo Nakano, Masataka Shiraki, +7 authors, Toshitaka Nakamura.
J Bone Miner Metab, 2013 Nov 12; 32(4). PMID: 24213216
Treatment of peripheral neuropathic pain by topical capsaicin: Impact of pre-existing pain in the QUEPP-study.
C G Maihöfner, M-L S Heskamp.
Eur J Pain, 2013 Nov 22; 18(5). PMID: 24259265    Free PMC article.
Analysis of individual items on the attention-deficit/hyperactivity disorder symptom rating scale in children and adults: the effects of age and sex in pivotal trials of lisdexamfetamine dimesylate.
Richard H Weisler, Lenard A Adler, +4 authors, Ann C Childress.
Neuropsychiatr Dis Treat, 2013 Dec 24; 10. PMID: 24363557    Free PMC article.
Meta-analysis: pitfalls and hints.
T Greco, A Zangrillo, G Biondi-Zoccai, G Landoni.
Heart Lung Vessel, 2013 Dec 24; 5(4). PMID: 24364016    Free PMC article.
Review.
Reassessing the benefits of statins in the prevention of cardiovascular disease in diabetic patients--a systematic review and meta-analysis.
Yu-Hung Chang, Ming-Chia Hsieh, +2 authors, Yau-Jiunn Lee.
Rev Diabet Stud, 2014 Jan 01; 10(2-3). PMID: 24380090    Free PMC article.
Systematic Review.
Multimorbidity and evidence generation.
Carlos O Weiss, Ravi Varadhan, +4 authors, David M Kent.
J Gen Intern Med, 2014 Jan 21; 29(4). PMID: 24442333    Free PMC article.
Review.
Cognitive function and brain structure in persons with type 2 diabetes mellitus after intensive lowering of blood pressure and lipid levels: a randomized clinical trial.
Jeff D Williamson, Lenore J Launer, +17 authors, Action to Control Cardiovascular Risk in Diabetes Memory in Diabetes Investigators.
JAMA Intern Med, 2014 Feb 05; 174(3). PMID: 24493100    Free PMC article.
Telephone-delivered psychotherapy for rural-dwelling older adults with generalized anxiety disorder: study protocol of a randomized controlled trial.
Gretchen A Brenes, Suzanne C Danhauer, Mary F Lyles, Michael E Miller.
BMC Psychiatry, 2014 Feb 11; 14. PMID: 24506950    Free PMC article.
Can 88% of patients with acute lower respiratory infection all be special?
Alastair D Hay, Kate Tilling.
Br J Gen Pract, 2014 Feb 26; 64(619). PMID: 24567585    Free PMC article.
Implications of Lifecourse Epidemiology for Research on Determinants of Adult Disease.
Sze Liu, Richard N Jones, M Maria Glymour.
Public Health Rev, 2010 Nov 01; 32(2). PMID: 24639598    Free PMC article.
Tight glycemic control after pediatric cardiac surgery in high-risk patient populations: a secondary analysis of the safe pediatric euglycemia after cardiac surgery trial.
Michael S D Agus, Lisa A Asaro, +5 authors, SPECS Investigators.
Circulation, 2014 Mar 29; 129(22). PMID: 24671945    Free PMC article.
A pooled analysis of gemcitabine plus docetaxel versus capecitabine plus docetaxel in metastatic breast cancer.
Andrew D Seidman, Stephen Chan, +3 authors, Binghe Xu.
Oncologist, 2014 Apr 08; 19(5). PMID: 24705980    Free PMC article.
Humoral response to a viral glycan correlates with survival on PROSTVAC-VF.
Christopher T Campbell, James L Gulley, +3 authors, Jeffrey C Gildersleeve.
Proc Natl Acad Sci U S A, 2014 Apr 16; 111(17). PMID: 24733910    Free PMC article.
Multidisciplinary team meeting in digestive oncology: when opinions differ.
Alban Zarzavadjian Le Bian, Renato Costi, +2 authors, Claude Smadja.
Clin Transl Sci, 2014 May 21; 7(4). PMID: 24841628    Free PMC article.
Improving the quality of adult mortality data collected in demographic surveys: validation study of a new siblings' survival questionnaire in Niakhar, Senegal.
Stéphane Helleringer, Gilles Pison, +5 authors, Valérie Delaunay.
PLoS Med, 2014 May 29; 11(5). PMID: 24866715    Free PMC article.
Behavioral treatment of chronic insomnia in older adults: does nocturia matter?
Shachi Tyagi, Neil M Resnick, +3 authors, Daniel J Buysse.
Sleep, 2014 Jun 06; 37(4). PMID: 24899759    Free PMC article.
The use of propensity scores to assess the generalizability of results from randomized trials.
Elizabeth A Stuart, Stephen R Cole, Catherine P Bradshaw, Philip J Leaf.
J R Stat Soc Ser A Stat Soc, 2001 Apr 01; 174(2). PMID: 24926156    Free PMC article.
Association between Serum Antibodies to Oral Microorganisms and Hyperglycemia in Adults.
A T Merchant, D Shrestha, +3 authors, J Zhang.
J Dent Res, 2014 Jun 20; 93(8). PMID: 24943202    Free PMC article.
The value of heterogeneity for cost-effectiveness subgroup analysis: conceptual framework and application.
Manuel A Espinoza, Andrea Manca, Karl Claxton, Mark J Sculpher.
Med Decis Making, 2014 Jun 20; 34(8). PMID: 24944196    Free PMC article.
Evidence for the selective reporting of analyses and discrepancies in clinical trials: a systematic review of cohort studies of clinical trials.
Kerry Dwan, Douglas G Altman, +5 authors, Jamie J Kirkham.
PLoS Med, 2014 Jun 25; 11(6). PMID: 24959719    Free PMC article.
Highly Cited. Systematic Review.
Conceptual and Analytical Considerations toward the Use of Patient-Reported Outcomes in Personalized Medicine.
Demissie Alemayehu, Joseph C Cappelleri.
Am Health Drug Benefits, 2012 Jul 01; 5(5). PMID: 24991329    Free PMC article.
Review.
Cost-effectiveness of a rapid response team intervention for suicidal youth presenting at an emergency department.
Eric A Latimer, Geneviéve Garièpy, Brian Greenfield.
Can J Psychiatry, 2014 Jul 10; 59(6). PMID: 25007405    Free PMC article.
Subgroup analyses in randomised controlled trials: cohort study on trial protocols and journal publications.
Benjamin Kasenda, Stefan Schandelmaier, +37 authors, DISCO Study Group.
BMJ, 2014 Jul 18; 349. PMID: 25030633    Free PMC article.
Challenges and solutions to pre- and post-randomization subgroup analyses.
Manisha Desai, Karen S Pieper, Ken Mahaffey.
Curr Cardiol Rep, 2014 Aug 20; 16(10). PMID: 25135344    Free PMC article.
Review.
Clinical effectiveness of CRT and ICD therapy in heart failure patients by racial/ethnic classification: insights from the IMPROVE HF registry.
Boback Ziaeian, Yan Zhang, +9 authors, Gregg C Fonarow.
J Am Coll Cardiol, 2014 Aug 26; 64(8). PMID: 25145524    Free PMC article.
Inference for environmental intervention studies using principal stratification.
Amber J Hackstadt, Elizabeth C Matsui, +4 authors, Roger D Peng.
Stat Med, 2014 Aug 29; 33(28). PMID: 25164949    Free PMC article.
Comparison of the effects of albumin and crystalloid on mortality in adult patients with severe sepsis and septic shock: a meta-analysis of randomized clinical trials.
Jing-Yuan Xu, Qi-Hong Chen, +9 authors, Hai-Bo Qiu.
Crit Care, 2014 Dec 17; 18(6). PMID: 25499187    Free PMC article.
Subgroup analysis as a source of spurious findings: an illustration using new data on alcohol intake and coronary heart disease.
Steven Bell, Mika Kivimäki, G David Batty.
Addiction, 2014 Dec 18; 110(1). PMID: 25515832    Free PMC article.
Interpreting the results of a retrospective comparison of test and reference treatments in a randomized clinical trial setting.
Moshe Fridman, M Haim Erder.
Clin Drug Investig, 2014 Dec 21; 35(2). PMID: 25526678    Free PMC article.
Effectiveness of a multifactorial intervention on preventing development of frailty in pre-frail older people: study protocol for a randomised controlled trial.
Nicola Fairhall, Susan E Kurrle, +6 authors, Ian D Cameron.
BMJ Open, 2015 Feb 11; 5(2). PMID: 25667151    Free PMC article.
Improving Patient Care Using the Johnson-Neyman Analysis of Heterogeneity of Treatment Effects According to Individuals' Baseline Characteristics.
Ann A Lazar, Stuart A Gansky, +2 authors, Jane A Weintraub.
J Dent Oral Craniofac Epidemiol, 2013 Oct 01; 1(3). PMID: 25705704    Free PMC article.
Detecting treatment-covariate interactions using permutation methods.
Rui Wang, David A Schoenfeld, Bettina Hoeppner, A Eden Evins.
Stat Med, 2015 Mar 05; 34(12). PMID: 25736915    Free PMC article.
A clustering method to identify who benefits most from the treatment group in clinical trials.
Beom S Lee, Pranab K Sen, +3 authors, David A Chiriboga.
Health Psychol Behav Med, 2014 Jan 01; 2(1). PMID: 25750814    Free PMC article.
Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma.
Joe K Gerald, Lynn B Gerald, +18 authors, Fernando D Martinez.
J Allergy Clin Immunol Pract, 2015 Mar 19; 3(4). PMID: 25783161    Free PMC article.
Estimates of absolute treatment benefit for individual patients required careful modeling of statistical interactions.
David van Klaveren, Yvonne Vergouwe, +2 authors, Ewout W Steyerberg.
J Clin Epidemiol, 2015 Mar 31; 68(11). PMID: 25814403    Free PMC article.
Estimation of treatment effect in a subpopulation: An empirical Bayes approach.
Changyu Shen, Xiaochun Li, Jaesik Jeong.
J Biopharm Stat, 2015 May 27; 26(3). PMID: 26010422    Free PMC article.
The comparative efficacy of lifestyle intervention and metformin by educational attainment in the Diabetes Prevention Program.
Matthew J O'Brien, Robert C Whitaker, Daohai Yu, Ronald T Ackermann.
Prev Med, 2015 May 31; 77. PMID: 26024851    Free PMC article.
Moderators of Varenicline Treatment Effects in a Double-Blind, Placebo-Controlled Trial for Alcohol Dependence: An Exploratory Analysis.
Daniel E Falk, I-Jen P Castle, +2 authors, Raye Z Litten.
J Addict Med, 2015 Jun 18; 9(4). PMID: 26083958    Free PMC article.
Effect of Structured Physical Activity on Sleep-Wake Behaviors in Sedentary Elderly Adults with Mobility Limitations.
Carlos A Vaz Fragoso, Michael E Miller, +8 authors, Lifestyle Interventions and Independence for Elders Study Group.
J Am Geriatr Soc, 2015 Jun 27; 63(7). PMID: 26115386    Free PMC article.
P2Y12 antagonists in non-ST-segment elevation acute coronary syndromes: latest evidence and optimal use.
Nicholas B Norgard, James J DiNicolantonio.
Ther Adv Chronic Dis, 2015 Jul 03; 6(4). PMID: 26137210    Free PMC article.
Review.
Electrocardiogram Derived QRS Duration >120 ms is Associated With Elevated Plasma Homocysteine Levels in a Rural Australian Cross-Sectional Population.
Yvonne Lee Yin Leng, Yuling Zhou, +4 authors, Craig S McLachlan.
Medicine (Baltimore), 2015 Jul 15; 94(27). PMID: 26166085    Free PMC article.
Regional Nodal Irradiation in Early-Stage Breast Cancer.
Timothy J Whelan, Ivo A Olivotto, +21 authors, MA.20 Study Investigators.
N Engl J Med, 2015 Jul 23; 373(4). PMID: 26200977    Free PMC article.
Highly Cited.
The Risk of Intraocular Pressure Elevation in Pediatric Noninfectious Uveitis.
Srishti Kothari, C Stephen Foster, +12 authors, Systemic Immunosuppressive Therapy for Eye Diseases Research Group.
Ophthalmology, 2015 Aug 04; 122(10). PMID: 26233626    Free PMC article.
Benefits of Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, and Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study.
Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group, John H Kempen, +5 authors, Jennifer E Thorne.
Ophthalmology, 2015 Aug 25; 122(10). PMID: 26298715    Free PMC article.
Quality of Life and Risks Associated with Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, or Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatment Trial and Follow-up Study.
Multicenter Uveitis Steroid Treatment (MUST) Trial Follow-up Study Research Group.
Ophthalmology, 2015 Aug 25; 122(10). PMID: 26298718    Free PMC article.
High-dose vitamin D3 in adults with pulmonary tuberculosis: a double-blind randomized controlled trial.
Nestan Tukvadze, Ekaterina Sanikidze, +14 authors, Thomas R Ziegler.
Am J Clin Nutr, 2015 Sep 25; 102(5). PMID: 26399865    Free PMC article.
Statistical Methods for Establishing Personalized Treatment Rules in Oncology.
Junsheng Ma, Brian P Hobbs, Francesco C Stingo.
Biomed Res Int, 2015 Oct 09; 2015. PMID: 26446492    Free PMC article.
Review.
Insulin Dose and Cardiovascular Mortality in the ACCORD Trial.
Elias S Siraj, Daniel J Rubin, +15 authors, ACCORD Investigators.
Diabetes Care, 2015 Oct 16; 38(11). PMID: 26464212    Free PMC article.
Identifying treatment effect heterogeneity in clinical trials using subpopulations of events: STEPP.
Ann A Lazar, Marco Bonetti, +2 authors, Richard D Gelber.
Clin Trials, 2015 Oct 24; 13(2). PMID: 26493094    Free PMC article.
Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations.
Stephen J Teach, Michelle A Gill, +17 authors, Stanley J Szefler.
J Allergy Clin Immunol, 2015 Nov 01; 136(6). PMID: 26518090    Free PMC article.
Highly Cited.
Comparison of Adipose Distribution Indices with Gold Standard Body Composition Assessments in the EMPA-REG H2H SU Trial: A Body Composition Sub-Study.
Ian J Neeland, Darren K McGuire, +5 authors, Odd Erik Johansen.
Diabetes Ther, 2015 Nov 27; 6(4). PMID: 26608511    Free PMC article.
Reply.
Michael M Ward, Atul Deodhar, John D Reveille, Liron Caplan.
Arthritis Rheumatol, 2015 Dec 05; 68(6). PMID: 26636978    Free PMC article.
Incomparable Subsequent Effects between Study and Control Fluids Might Cause Questionable Results in Randomized Controlled Trials.
Peng-Lin Ma, Yang Wang, Xiao-Lan Hu.
Chin Med J (Engl), 2015 Dec 30; 129(1). PMID: 26712450    Free PMC article.
Examining the Efficacy of HIV Risk-Reduction Counseling on the Sexual Risk Behaviors of a National Sample of Drug Abuse Treatment Clients: Analysis of Subgroups.
Lauren Gooden, Lisa R Metsch, +6 authors, Daniel J Feaster.
AIDS Behav, 2016 Feb 04; 20(9). PMID: 26837631    Free PMC article.
Subgroup analyses in confirmatory clinical trials: time to be specific about their purposes.
Julien Tanniou, Ingeborg van der Tweel, Steven Teerenstra, Kit C B Roes.
BMC Med Res Methodol, 2016 Feb 20; 16. PMID: 26891992    Free PMC article.
Review.
Qualitative Treatment-Subgroup Interactions in a Randomized Clinical Trial of Treatments for Adolescents with ADHD: Exploring What Cognitive-Behavioral Treatment Works for Whom.
Bianca E Boyer, Lisa L Doove, +3 authors, Saskia Van der Oord.
PLoS One, 2016 Mar 16; 11(3). PMID: 26977602    Free PMC article.
Use of fibrates in the metabolic syndrome: A review.
Kate E Shipman, Richard C Strange, Sudarshan Ramachandran.
World J Diabetes, 2016 Mar 17; 7(5). PMID: 26981181    Free PMC article.
Review.
Reply.
Michael M Ward, Atul Deodhar, John D Reveille, Liron Caplan.
Arthritis Care Res (Hoboken), 2016 Mar 19; 68(6). PMID: 26990665    Free PMC article.
Individualized Household Allergen Intervention Lowers Allergen Level But Not Asthma Medication Use: A Randomized Controlled Trial.
Emily DiMango, Denise Serebrisky, +11 authors, Meyer Kattan.
J Allergy Clin Immunol Pract, 2016 Mar 31; 4(4). PMID: 27025297    Free PMC article.
Subpopulation Treatment Effect Pattern Plot (STEPP) analysis for continuous, binary, and count outcomes.
Wai-Ki Yip, Marco Bonetti, +4 authors, Richard D Gelber.
Clin Trials, 2016 Apr 21; 13(4). PMID: 27094489    Free PMC article.
The Influence of Treatment Motivation on Outcomes of Social Skills Training for Juvenile Delinquents.
Trudy van der Stouwe, Jessica J Asscher, +2 authors, Geert Jan J M Stams.
Int J Offender Ther Comp Criminol, 2016 May 27; 62(1). PMID: 27225504    Free PMC article.
Weak evidence on nalmefene creates dilemmas for clinicians and poses questions for regulators and researchers.
Niamh Fitzgerald, Kathryn Angus, +4 authors, Jim McCambridge.
Addiction, 2016 Jun 06; 111(8). PMID: 27262594    Free PMC article.
Review.
Warfarin Treatment and All-Cause Mortality in Community-Dwelling Older Adults with Atrial Fibrillation: A Retrospective Observational Study.
Alberto Pilotto, Pietro Gallina, +9 authors, Multidimensional Prognostic Index_Age Project Investigators.
J Am Geriatr Soc, 2016 Jun 14; 64(7). PMID: 27295351    Free PMC article.
Can we use baseline characteristics to assess which men with moderately symptomatic benign prostatic hyperplasia at risk of progression will benefit from treatment? A post hoc analysis of data from the 2-year CONDUCT study.
Claus G Roehrborn, Igor Oyarzabal Perez, +5 authors, Michael J Manyak.
World J Urol, 2016 Jun 24; 35(3). PMID: 27334136    Free PMC article.
Preventive Ceftriaxone in Patients with Stroke Treated with Intravenous Thrombolysis: Post Hoc Analysis of the Preventive Antibiotics in Stroke Study.
Jan-Dirk Vermeij, Willeke F Westendorp, +4 authors, PASS Investigators.
Cerebrovasc Dis, 2016 Jun 24; 42(5-6). PMID: 27336314    Free PMC article.
No improvement in the reporting of clinical trial subgroup effects in high-impact general medical journals.
Nicole B Gabler, Naihua Duan, +6 authors, Richard L Kravitz.
Trials, 2016 Jul 18; 17(1). PMID: 27423688    Free PMC article.
Does education level affect the efficacy of a community based salt reduction program? - A post-hoc analysis of the China Rural Health Initiative Sodium Reduction Study (CRHI-SRS).
Xin Wang, Xian Li, +4 authors, Yangfeng Wu.
BMC Public Health, 2016 Aug 16; 16(1). PMID: 27515930    Free PMC article.
Efficacy of Internet-Based Self-Monitoring Interventions on Maternal and Neonatal Outcomes in Perinatal Diabetic Women: A Systematic Review and Meta-Analysis.
Ying Lau, Tha Pyai Htun, +2 authors, Piyanee Klainin-Yobas.
J Med Internet Res, 2016 Aug 17; 18(8). PMID: 27526637    Free PMC article.
Systematic Review.
Aliskiren/amlodipine as a single-pill combination in hypertensive patients: subgroup analysis of elderly patients, with metabolic risk factors or high body mass index.
Christoph Axthelm, Christian Sieder, +2 authors, Edelgard Kaiser.
J Drug Assess, 2013 Jan 01; 2(1). PMID: 27536431    Free PMC article.
Multivariable fractional polynomial interaction to investigate continuous effect modifiers in a meta-analysis on higher versus lower PEEP for patients with ARDS.
Benjamin Kasenda, Willi Sauerbrei, +9 authors, Matthias Briel.
BMJ Open, 2016 Sep 10; 6(9). PMID: 27609843    Free PMC article.
Systematic Review.
Relation of Statin Use and Mortality in Community-Dwelling Frail Older Patients With Coronary Artery Disease.
Alberto Pilotto, Pietro Gallina, +15 authors, MPI_AGE Project Investigators.
Am J Cardiol, 2016 Sep 28; 118(11). PMID: 27670793    Free PMC article.
Outcome Reporting Bias in Government-Sponsored Policy Evaluations: A Qualitative Content Analysis of 13 Studies.
Arnaud Vaganay.
PLoS One, 2016 Oct 01; 11(9). PMID: 27690131    Free PMC article.
Patient characteristics associated with greater blood pressure control in a randomized trial of home blood pressure telemonitoring and pharmacist management.
Stephen E Asche, Patrick J O'Connor, +8 authors, Karen L Margolis.
J Am Soc Hypertens, 2016 Oct 11; 10(11). PMID: 27720142    Free PMC article.
Effect of early postextubation high-flow nasal cannula vs conventional oxygen therapy on hypoxaemia in patients after major abdominal surgery: a French multicentre randomised controlled trial (OPERA).
Emmanuel Futier, Catherine Paugam-Burtz, +11 authors, OPERA study investigators.
Intensive Care Med, 2016 Oct 25; 42(12). PMID: 27771739
Time to share: lessons from post hoc analyses of IPF trials.
Daniel J Kass, Naftali Kaminski.
Thorax, 2016 Oct 30; 72(2). PMID: 27789650    Free PMC article.
Subgroup analyses of randomized clinical trials in heart failure: facts and numbers.
Andrija Vidic, John T Chibnall, Niharika Goparaju, Paul J Hauptman.
ESC Heart Fail, 2016 Nov 15; 3(3). PMID: 27840693    Free PMC article.
Using group data to treat individuals: understanding heterogeneous treatment effects in the age of precision medicine and patient-centred evidence.
Issa J Dahabreh, Rodney Hayward, David M Kent.
Int J Epidemiol, 2016 Nov 20; 45(6). PMID: 27864403    Free PMC article.
Bayesian analysis of heterogeneous treatment effects for patient-centered outcomes research.
Nicholas C Henderson, Thomas A Louis, Chenguang Wang, Ravi Varadhan.
Health Serv Outcomes Res Methodol, 2016 Nov 25; 16(4). PMID: 27881932    Free PMC article.
Sex based subgroup differences in randomized controlled trials: empirical evidence from Cochrane meta-analyses.
Joshua D Wallach, Patrick G Sullivan, +2 authors, John P A Ioannidis.
BMJ, 2016 Nov 26; 355. PMID: 27884869    Free PMC article.
Local Vascular Gene Therapy With Apolipoprotein A-I to Promote Regression of Atherosclerosis.
Bradley K Wacker, Nagadhara Dronadula, Jingwan Zhang, David A Dichek.
Arterioscler Thromb Vasc Biol, 2016 Dec 10; 37(2). PMID: 27932352    Free PMC article.
Comparison of Etomidate and Ketamine for Induction During Rapid Sequence Intubation of Adult Trauma Patients.
Cameron P Upchurch, Carlos G Grijalva, +9 authors, Wesley H Self.
Ann Emerg Med, 2016 Dec 21; 69(1). PMID: 27993308    Free PMC article.
Blood pressure reduction in acute ischemic stroke according to time to treatment: a subgroup analysis of the China Antihypertensive Trial in Acute Ischemic Stroke trial.
Tan Xu, Yonghong Zhang, +25 authors, CATIS investigators.
J Hypertens, 2017 Feb 09; 35(6). PMID: 28169880    Free PMC article.
Recombinant factor VIIa for variceal bleeding in liver cirrhosis: still only a hope.
Xingshun Qi, Chun Ye, Xiaozhong Guo.
Arch Med Sci, 2017 Mar 07; 13(2). PMID: 28261306    Free PMC article.
Reporting and Guidelines in Propensity Score Analysis: A Systematic Review of Cancer and Cancer Surgical Studies.
Xiaoxin I Yao, Xiaofei Wang, +6 authors, Herbert H Pang.
J Natl Cancer Inst, 2017 Apr 05; 109(8). PMID: 28376195    Free PMC article.
Highly Cited. Systematic Review.
Trends of medical expenditures and quality of life in US adults with diabetes: the medical expenditure panel survey, 2002-2011.
Jennifer A Campbell, Kinfe G Bishu, Rebekah J Walker, Leonard E Egede.
Health Qual Life Outcomes, 2017 Apr 15; 15(1). PMID: 28407776    Free PMC article.
Saline versus balanced crystalloids for intravenous fluid therapy in the emergency department: study protocol for a cluster-randomized, multiple-crossover trial.
Wesley H Self, Matthew W Semler, +10 authors, Todd W Rice.
Trials, 2017 Apr 15; 18(1). PMID: 28407811    Free PMC article.
Eribulin Approval in Advanced Liposarcoma - Successful Drug or a Weaker Methodology?
Sameer Rastogi, Vineet Gupta.
Indian J Med Paediatr Oncol, 2017 May 05; 38(1). PMID: 28469328    Free PMC article.
Quality of life as indicator of poor outcome in hemodialysis: relation with mortality in different age groups.
I N van Loon, M L Bots, +7 authors, M E Hamaker.
BMC Nephrol, 2017 Jul 07; 18(1). PMID: 28679361    Free PMC article.
Does recruitment source moderate treatment effectiveness? A subgroup analysis from the EVIDENT study, a randomised controlled trial of an internet intervention for depressive symptoms.
Jan Philipp Klein, Carla Gamon, +8 authors, Johanna Schröder.
BMJ Open, 2017 Jul 16; 7(7). PMID: 28710212    Free PMC article.
Subgroup analysis and interaction tests: why they are important and how to avoid common mistakes.
Juliana Carvalho Ferreira, Cecilia Maria Patino.
J Bras Pneumol, 2017 Jul 27; 43(3). PMID: 28746525    Free PMC article.
Change-Plane Analysis for Subgroup Detection and Sample Size Calculation.
Ailin Fan, Rui Song, Wenbin Lu.
J Am Stat Assoc, 2017 Aug 15; 112(518). PMID: 28804182    Free PMC article.
Effectiveness of a Timing and Coordination Group Exercise Program to Improve Mobility in Community-Dwelling Older Adults: A Randomized Clinical Trial.
Jennifer S Brach, Subashan Perera, +4 authors, Edmund Ricci.
JAMA Intern Med, 2017 Aug 15; 177(10). PMID: 28806436    Free PMC article.
Identifying Which Urban Children With Asthma Benefit Most From Clinician Prompting: Subgroup Analyses From the Prompting Asthma Intervention in Rochester-Uniting Parents and Providers (PAIR-UP) Trial.
Nicolas P N Goldstein, Sean M Frey, +2 authors, Jill S Halterman.
Acad Pediatr, 2017 Sep 14; 18(3). PMID: 28899842    Free PMC article.
Adjuvant Chemotherapy vs Postoperative Observation Following Preoperative Chemoradiotherapy and Resection in Gastroesophageal Cancer: A Propensity Score-Matched Analysis.
Ali A Mokdad, Adam C Yopp, +7 authors, Matthew R Porembka.
JAMA Oncol, 2017 Oct 05; 4(1). PMID: 28975352    Free PMC article.
Meta-analysis of pharmacogenetic interactions in amyotrophic lateral sclerosis clinical trials.
Ruben P A van Eijk, Ashley R Jones, +19 authors, For UKMND-LiCALS and LITALS Study Group.
Neurology, 2017 Oct 06; 89(18). PMID: 28978660    Free PMC article.
Review.
Mortality Benefit of Recombinant Human Interleukin-1 Receptor Antagonist for Sepsis Varies by Initial Interleukin-1 Receptor Antagonist Plasma Concentration.
Nuala J Meyer, John P Reilly, +7 authors, Steven M Opal.
Crit Care Med, 2017 Oct 11; 46(1). PMID: 28991823    Free PMC article.
Improving Depression Care for Adults With Serious Mental Illness in Underresourced Areas: Community Coalitions Versus Technical Support.
Enrico G Castillo, Roderick Shaner, +5 authors, Kenneth B Wells.
Psychiatr Serv, 2017 Oct 17; 69(2). PMID: 29032700    Free PMC article.
Correlation between Thyroid Stimulating Hormone and Renal Function in Euthyroid Residents of Japan: Results from the Kyushu and Okinawa Population Study (KOPS).
Yuki Tanaka, Norihiro Furusyo, +5 authors, Jun Hayashi.
J Atheroscler Thromb, 2017 Oct 20; 25(4). PMID: 29046502    Free PMC article.
Serious Adverse Events Among SPRINT Trial Participants Taking Statins at Baseline.
Marco D Huesch.
Drugs R D, 2017 Oct 24; 17(4). PMID: 29058304    Free PMC article.
Effect of Vitamin D Supplementation on Arterial Stiffness and Central Blood Pressure Indexes: Demystifying the Evidence.
Pankaj Arora, Thomas J Wang.
J Am Heart Assoc, 2017 Oct 27; 6(10). PMID: 29066449    Free PMC article.
Long-term impact of intensive lifestyle intervention on cognitive function assessed with the National Institutes of Health Toolbox: The Look AHEAD study.
Kathleen M Hayden, Laura D Baker, +11 authors, Michael E Miller.
Alzheimers Dement (Amst), 2017 Nov 22; 10. PMID: 29159267    Free PMC article.
Extracorporeal cellular therapy (ELAD) in severe alcoholic hepatitis: A multinational, prospective, controlled, randomized trial.
Julie Thompson, Natasha Jones, +41 authors, VTI-208 Study Group.
Liver Transpl, 2017 Nov 25; 24(3). PMID: 29171941    Free PMC article.
Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial.
Guy E Thwaites, Matthew Scarborough, +35 authors, United Kingdom Clinical Infection Research Group (UKCIRG).
Lancet, 2017 Dec 19; 391(10121). PMID: 29249276    Free PMC article.
Reporting of heterogeneity of treatment effect in cohort studies: a review of the literature.
Meryl Dahan, Caroline Scemama, Raphael Porcher, David J Biau.
BMC Med Res Methodol, 2018 Jan 14; 18(1). PMID: 29329525    Free PMC article.
Review.
The relationship between asthma and depression in a community-based sample.
Mahima Akula, Alexandra Kulikova, David A Khan, E Sherwood Brown.
J Asthma, 2018 Jan 18; 55(12). PMID: 29336633    Free PMC article.
Effect of the Apolipoprotein E Genotype on Cognitive Change During a Multidomain Lifestyle Intervention: A Subgroup Analysis of a Randomized Clinical Trial.
Alina Solomon, Heidi Turunen, +17 authors, Miia Kivipelto.
JAMA Neurol, 2018 Jan 23; 75(4). PMID: 29356827    Free PMC article.
Highly Cited.
A recursive partitioning approach for subgroup identification in individual patient data meta-analysis.
Dipesh Mistry, Nigel Stallard, Martin Underwood.
Stat Med, 2018 Feb 01; 37(9). PMID: 29383818    Free PMC article.
A Critical Examination of Subgroup Analyses: The National Acute Spinal Cord Injury Studies and Beyond.
Shannon Hextrum, Stephanie Bennett.
Front Neurol, 2018 Feb 17; 9. PMID: 29449826    Free PMC article.
Review.
Balanced Crystalloids versus Saline in Noncritically Ill Adults.
Wesley H Self, Matthew W Semler, +11 authors, SALT-ED Investigators.
N Engl J Med, 2018 Feb 28; 378(9). PMID: 29485926    Free PMC article.
Highly Cited.
The Risk of Acute Pancreatitis After Initiation of Dipeptidyl Peptidase 4 Inhibitors: Testing a Hypothesis of Subgroup Differences in Older U.S. Adults.
Jin-Liern Hong, John B Buse, +2 authors, Til Stürmer.
Diabetes Care, 2018 Apr 06; 41(6). PMID: 29618573    Free PMC article.
E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium.
Hisani N Horne, Hannah Oh, +49 authors, Jonine D Figueroa.
Sci Rep, 2018 Apr 28; 8(1). PMID: 29700408    Free PMC article.
Association of Adjuvant Chemotherapy With Overall Survival in Patients With Rectal Cancer and Pathologic Complete Response Following Neoadjuvant Chemotherapy and Resection.
Patricio M Polanco, Ali A Mokdad, +2 authors, Sergio Huerta.
JAMA Oncol, 2018 May 02; 4(7). PMID: 29710272    Free PMC article.
Weighing the Evidence of Efficacy of Oral PrEP for HIV Prevention in Women in Southern Africa.
Holly Janes, Lawrence Corey, +5 authors, Glenda E Gray.
AIDS Res Hum Retroviruses, 2018 May 08; 34(8). PMID: 29732896    Free PMC article.
Review.
Raltegravir 1200 mg Once Daily vs 400 mg Twice Daily, With Emtricitabine and Tenofovir Disoproxil Fumarate, for Previously Untreated HIV-1 Infection: Week 96 Results From ONCEMRK, a Randomized, Double-Blind, Noninferiority Trial.
Pedro Cahn, Paul E Sax, +13 authors, ONCEMRK Study Group.
Journal of acquired immune deficiency syndromes (1999), 2018 May 18; 78(5). PMID: 29771789    Free PMC article.
The age of blood in pediatric intensive care units (ABC PICU): study protocol for a randomized controlled trial.
Marisa Tucci, Jacques Lacroix, +16 authors, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.
Trials, 2018 Jul 30; 19(1). PMID: 30055634    Free PMC article.
Diversity in Medical Device Clinical Trials: Do We Know What Works for Which Patients?
Stephanie R Fox-Rawlings, Laura B Gottschalk, Laurén A Doamekpor, Diana M Zuckerman.
Milbank Q, 2018 Sep 12; 96(3). PMID: 30203600    Free PMC article.
Association of tumor differentiation grade and survival of women with squamous cell carcinoma of the uterine cervix.
Koji Matsuo, Rachel S Mandelbaum, +4 authors, Jason D Wright.
J Gynecol Oncol, 2018 Sep 13; 29(6). PMID: 30207099    Free PMC article.
Femoroacetabular Impingement Randomised controlled Trial (FIRST) - a multi-centre randomized controlled trial comparing arthroscopic lavage and arthroscopic osteochondroplasty on patient important outcomes and quality of life in the treatment of young adult (18-50 years) femoroacetabular impingement: a statistical analysis plan.
Nicole Simunovic, D Heels-Ansdell, +2 authors, FIRST Investigators.
Trials, 2018 Oct 31; 19(1). PMID: 30373659    Free PMC article.
Angiotensin II Brings More Questions Than Answers.
Nicholas Farina, Alexandra Bixby, Cesar Alaniz.
P T, 2018 Nov 10; 43(11). PMID: 30410284    Free PMC article.
Rates and Impact of Adherence to Recommended Care for Unhealthy Alcohol Use.
Kimberly A Hepner, Susan M Paddock, +6 authors, Harold Alan Pincus.
J Gen Intern Med, 2018 Nov 30; 34(2). PMID: 30484101    Free PMC article.
Psychological outcomes following a nurse-led preventative psychological intervention for critically ill patients trial: Statistical and health economic analysis plan.
Jerome Wulff, Zia Sadique, +5 authors, David A Harrison.
J Intensive Care Soc, 2018 Dec 06; 19(4). PMID: 30515237    Free PMC article.
Personalized evidence based medicine: predictive approaches to heterogeneous treatment effects.
David M Kent, Ewout Steyerberg, David van Klaveren.
BMJ, 2018 Dec 12; 363. PMID: 30530757    Free PMC article.
Highly Cited. Review.
Effective Visual Communication for the Quantitative Scientist.
Marc Vandemeulebroecke, Mark Baillie, Alison Margolskee, Baldur Magnusson.
CPT Pharmacometrics Syst Pharmacol, 2019 Jul 23; 8(10). PMID: 31329354    Free PMC article.
Improving the reporting quality of intervention trials addressing the inter-individual variability in response to the consumption of plant bioactives: quality index and recommendations.
Marina Nikolic, Aleksandra Konic Ristic, +20 authors, Pedro Mena.
Eur J Nutr, 2019 Sep 08; 58(Suppl 2). PMID: 31492976    Free PMC article.
Review.
Age-treatment subgroup analyses in Cochrane intervention reviews: a meta-epidemiological study.
Patrick Liu, John P A Ioannidis, +4 authors, Joshua D Wallach.
BMC Med, 2019 Oct 23; 17(1). PMID: 31639007    Free PMC article.
A comparison of the statistical performance of different meta-analysis models for the synthesis of subgroup effects from randomized clinical trials.
Bruno R da Costa, Alex J Sutton.
BMC Med Res Methodol, 2019 Oct 28; 19(1). PMID: 31655550    Free PMC article.
A randomized trial of a specialist palliative care intervention for patients undergoing surgery for cancer: rationale and design of the Surgery for Cancer with Option of Palliative Care Expert (SCOPE) Trial.
Myrick C Shinall, Aimee Hoskins, +10 authors, E Wesley Ely.
Trials, 2019 Dec 13; 20(1). PMID: 31829237    Free PMC article.
The premature closure of ROMPA clinical trial: mortality reduction in septic shock by plasma adsorption.
Carola Giménez-Esparza, Cristina Portillo-Requena, +17 authors, Vicente F Gil-Guillen.
BMJ Open, 2019 Dec 05; 9(12). PMID: 31796477    Free PMC article.
Program to improve mobility in aging (PRIMA) study: Methods and rationale of a task-oriented motor learning exercise program.
Jennifer S Brach, Jessie M VanSwearingen, +4 authors, Subashan Perera.
Contemp Clin Trials, 2019 Dec 16; 89. PMID: 31838258    Free PMC article.
Low-fat dietary pattern and global cognitive function: Exploratory analyses of the Women's Health Initiative (WHI) randomized Dietary Modification trial.
Rowan T Chlebowski, Steve Rapp, +12 authors, Ross L Prentice.
EClinicalMedicine, 2020 Jan 16; 18. PMID: 31938786    Free PMC article.
What is the effect of a decision aid in potentially vulnerable parents? Insights from the head CT choice randomized trial.
Rachel M Skains, Nathan Kuppermann, +12 authors, Erik P Hess.
Health Expect, 2019 Nov 24; 23(1). PMID: 31758633    Free PMC article.
Tumor treating fields plus temozolomide for newly diagnosed glioblastoma: a sub-group analysis of Korean patients in the EF-14 phase 3 trial.
Chae-Yong Kim, Sun Ha Paek, +5 authors, Se-Hyuk Kim.
J Neurooncol, 2020 Feb 06; 146(3). PMID: 32020470
Lasmiditan for the acute treatment of migraine: Subgroup analyses by prior response to triptans.
Kerry Knievel, Andrew S Buchanan, +6 authors, Joshua Tobin.
Cephalalgia, 2019 Nov 21; 40(1). PMID: 31744319    Free PMC article.
Subgroups from regression trees with adjustment for prognostic effects and postselection inference.
Wei-Yin Loh, Michael Man, Shuaicheng Wang.
Stat Med, 2018 Apr 20; 38(4). PMID: 29671896    Free PMC article.
Evaluation of Differences in Individual Treatment Response in Schizophrenia Spectrum Disorders: A Meta-analysis.
Stephanie Winkelbeiner, Stefan Leucht, John M Kane, Philipp Homan.
JAMA Psychiatry, 2019 Jun 04; 76(10). PMID: 31158853    Free PMC article.
Privacy-Preserving Generative Deep Neural Networks Support Clinical Data Sharing.
Brett K Beaulieu-Jones, Zhiwei Steven Wu, +4 authors, Casey S Greene.
Circ Cardiovasc Qual Outcomes, 2019 Jul 10; 12(7). PMID: 31284738    Free PMC article.
Clinical and Genomic Risk to Guide the Use of Adjuvant Therapy for Breast Cancer.
Joseph A Sparano, Robert J Gray, +27 authors, George W Sledge.
N Engl J Med, 2019 Jun 04; 380(25). PMID: 31157962    Free PMC article.
Highly Cited.
Association between Tuberculosis, Statin Use, and Diabetes: A Propensity Score-Matched Analysis.
Min-Chul Kim, Sung-Cheol Yun, +4 authors, Sung-Han Kim.
Am J Trop Med Hyg, 2019 Jul 03; 101(2). PMID: 31264561    Free PMC article.
Assessing heterogeneity of treatment effect analyses in health-related cluster randomized trials: A systematic review.
Monique Anderson Starks, Gillian D Sanders, +7 authors, Adrian F Hernandez.
PLoS One, 2019 Aug 14; 14(8). PMID: 31404063    Free PMC article.
Systematic Review.
Benefit of second-line systemic chemotherapy for advanced biliary tract cancer: A propensity score analysis.
Florian Moik, Jakob M Riedl, +13 authors, Florian Posch.
Sci Rep, 2019 Apr 05; 9(1). PMID: 30944390    Free PMC article.
Early antihypertensive treatment and clinical outcomes in acute ischemic stroke: subgroup analysis by baseline blood pressure.
William J He, Chongke Zhong, +16 authors, CATIS investigators.
J Hypertens, 2018 Feb 02; 36(6). PMID: 29389742    Free PMC article.
Parasitic pharmacology: A plausible mechanism of action for cannabidiol.
Geert Jan Groeneveld, Jennifer H Martin.
Br J Clin Pharmacol, 2019 Jul 11; 86(2). PMID: 31290177    Free PMC article.
Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate is Non-inferior to Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment-naive Adults With Human Immunodeficiency Virus-1 Infection: Week 48 Results of the DRIVE-AHEAD Trial.
Chloe Orkin, Kathleen E Squires, +15 authors, DRIVE-AHEAD Study Group.
Clin Infect Dis, 2018 Sep 06; 68(4). PMID: 30184165    Free PMC article.
Highly Cited.
Quantitative lymph node burden as a 'very-high-risk' factor identifying head and neck cancer patients benefiting from postoperative chemoradiation.
Z S Zumsteg, M Luu, +7 authors, A S Ho.
Ann Oncol, 2018 Nov 06; 30(1). PMID: 30395159    Free PMC article.
Cardiometabolic risk factors in vegans; A meta-analysis of observational studies.
Jocelyne R Benatar, Ralph A H Stewart.
PLoS One, 2018 Dec 21; 13(12). PMID: 30571724    Free PMC article.
Review.
The Clinical Utility of a Precision Medicine Blood Test Incorporating Age, Sex, and Gene Expression for Evaluating Women with Stable Symptoms Suggestive of Obstructive Coronary Artery Disease: Analysis from the PRESET Registry.
Burcu Gul, Alexandra Lansky, +7 authors, Joseph A Ladapo.
J Womens Health (Larchmt), 2019 Jan 18; 28(5). PMID: 30653377    Free PMC article.
Sleeve Gastrectomy Weight Loss and the Preoperative and Postoperative Predictors: a Systematic Review.
Samuel Cottam, Daniel Cottam, Austin Cottam.
Obes Surg, 2019 Jan 21; 29(4). PMID: 30661210
Systematic Review.
For Whom Is Anti-Bullying Intervention Most Effective? The Role of Temperament.
Annalaura Nocentini, Benedetta Emanuela Palladino, Ersilia Menesini.
Int J Environ Res Public Health, 2019 Feb 02; 16(3). PMID: 30704025    Free PMC article.
Selecting Optimal Subgroups for Treatment Using Many Covariates.
Tyler J VanderWeele, Alex R Luedtke, Mark J van der Laan, Ronald C Kessler.
Epidemiology, 2019 Feb 23; 30(3). PMID: 30789432    Free PMC article.
Effectiveness of Implementing a Collaborative Chronic Care Model for Clinician Teams on Patient Outcomes and Health Status in Mental Health: A Randomized Clinical Trial.
Mark S Bauer, Christopher J Miller, +9 authors, Kendra Weaver.
JAMA Netw Open, 2019 Mar 02; 2(3). PMID: 30821830    Free PMC article.
Pantoprazole prophylaxis in ICU patients with high severity of disease: a post hoc analysis of the placebo-controlled SUP-ICU trial.
Søren Marker, Anders Perner, +10 authors, SUP-ICU investigators.
Intensive Care Med, 2019 Mar 14; 45(5). PMID: 30863936
Metabolic, mitochondrial, renal and hepatic safety of enfuvirtide and raltegravir antiretroviral administration: Randomized crossover clinical trial in healthy volunteers.
Sergio Barroso, Constanza Morén, +15 authors, Esteban Martínez.
PLoS One, 2019 May 24; 14(5). PMID: 31120908    Free PMC article.
Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER).
Ruth Stephen, Yawu Liu, +16 authors, FINGER study group.
Alzheimers Res Ther, 2019 Jun 06; 11(1). PMID: 31164160    Free PMC article.
Cardiovascular risk reduction with once-weekly semaglutide in subjects with type 2 diabetes: a post hoc analysis of gender, age, and baseline CV risk profile in the SUSTAIN 6 trial.
Lawrence A Leiter, Stephen C Bain, +6 authors, Ildiko Lingvay.
Cardiovasc Diabetol, 2019 Jun 07; 18(1). PMID: 31167654    Free PMC article.
Does evidence support the high expectations placed in precision medicine? A bibliographic review.
Jordi Cortés, José Antonio González, +6 authors, Erik Cobo.
F1000Res, 2018 Jan 09; 7. PMID: 31143439    Free PMC article.
Review.
Carrying out streamlined routine data analyses with reports for observational studies: introduction to a series of generic SAS ® macros.
Yuan Liu, Dana C Nickleach, +2 authors, Jeanne Kowalski.
F1000Res, 2019 Jun 27; 7. PMID: 31231506    Free PMC article.
The relationship between prenatal psychological stress and placental abruption in Japan, The Japan Environment and Children's Study (JECS).
Yasuyuki Kawanishi, Eiji Yoshioka, +12 authors, Japan Environment and Children’s Study Group.
PLoS One, 2019 Jul 10; 14(7). PMID: 31283785    Free PMC article.
Closed testing using surrogate hypotheses with restricted alternatives.
John M Lachin, Ionut Bebu, Michael D Larsen, Naji Younes.
PLoS One, 2019 Jul 13; 14(7). PMID: 31299051    Free PMC article.
Bayesian credible subgroup identification for treatment effectiveness in time-to-event data.
Duy Ngo, Richard Baumgartner, +3 authors, Patrick Schnell.
PLoS One, 2020 Feb 27; 15(2). PMID: 32101562    Free PMC article.
Heterogeneous treatment effects of a text messaging smoking cessation intervention among university students.
Marcus Bendtsen.
PLoS One, 2020 Mar 07; 15(3). PMID: 32134977    Free PMC article.
Examination of Injury, Host, and Social-Environmental Moderators of Online Family Problem Solving Treatment Efficacy for Pediatric Traumatic Brain Injury Using an Individual Participant Data Meta-Analytic Approach.
Nanhua Zhang, Eloise E Kaizar, +4 authors, Shari L Wade.
J Neurotrauma, 2018 Oct 18; 36(7). PMID: 30328749    Free PMC article.
Heterogeneous impact of cytomegalovirus reactivation on nonrelapse mortality in hematopoietic stem cell transplantation.
Satoshi Kaito, Yujiro Nakajima, +15 authors, Kazuteru Ohashi.
Blood Adv, 2020 Mar 20; 4(6). PMID: 32191806    Free PMC article.
Effectiveness of Iodophor vs Chlorhexidine Solutions for Surgical Site Infections and Unplanned Reoperations for Patients Who Underwent Fracture Repair: The PREP-IT Master Protocol.
Program of Randomized Trials to Evaluate Pre-operative Antiseptic Skin Solutions in Orthopaedic Trauma (PREP-IT) Investigators, Gerard P Slobogean, +45 authors, Uyen Nguyen.
JAMA Netw Open, 2020 Apr 08; 3(4). PMID: 32259266    Free PMC article.
Association Between Preoperative Metformin Exposure and Postoperative Outcomes in Adults With Type 2 Diabetes.
Katherine M Reitz, Oscar C Marroquin, +15 authors, Matthew D Neal.
JAMA Surg, 2020 Apr 09; 155(6). PMID: 32267474    Free PMC article.
Exploring refinements in targeted behavioral medicine intervention to advance public health.
Abby C King, David F Ahn, Audie A Atienza, Helena C Kraemer.
Ann Behav Med, 2008 Jun 24; 35(3). PMID: 18568380    Free PMC article.
Disparity of Race Reporting and Representation in Clinical Trials Leading to Cancer Drug Approvals From 2008 to 2018.
Jonathan M Loree, Seerat Anand, +7 authors, Kanwal Raghav.
JAMA Oncol, 2019 Aug 16;. PMID: 31415071    Free PMC article.
One-year clinical outcomes of patients treated with polymer-free amphilimus-eluting stents or zotarolimus-eluting stents: A propensity-score adjusted analysis.
Rik Rozemeijer, Ivar G van Muiden, +7 authors, Pieter R Stella.
Catheter Cardiovasc Interv, 2019 Jan 04; 94(1). PMID: 30604493    Free PMC article.
Effects of gentrification on health status after Hurricane Katrina.
Alina Schnake-Mahl, Benjamin D Sommers, +2 authors, Mariana Arcaya.
Health Place, 2019 Nov 20; 61. PMID: 31740125    Free PMC article.
5-0 Polypropylene versus 5-0 fast absorbing plain gut for cutaneous wound closure: a randomized evaluator blind trial.
Daniel Brian Eisen, Anne Rang Zhuang, +3 authors, Milene Kennedy Crispin.
Arch Dermatol Res, 2019 Nov 15; 312(3). PMID: 31724097    Free PMC article.
Association of Patient Demographic Characteristics and Insurance Status With Survival in Cancer Randomized Clinical Trials With Positive Findings.
Joseph M Unger, Charles D Blanke, +4 authors, Dawn L Hershman.
JAMA Netw Open, 2020 May 01; 3(4). PMID: 32352530    Free PMC article.
Interaction of Resistin and Systolic Blood Pressure in Psoriasis Severity.
Divya Seth, Alexa N Ehlert, +4 authors, Kevin D Cooper.
J Invest Dermatol, 2019 Nov 18; 140(6). PMID: 31734188    Free PMC article.
Efficacy of e-technologies in improving breastfeeding outcomes among perinatal women: a meta-analysis.
Ying Lau, Tha P Htun, Wai S W Tam, Piyanee Klainin-Yobas.
Matern Child Nutr, 2015 Jul 22; 12(3). PMID: 26194599    Free PMC article.
Review.
Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial.
Scott E Kasner, Balakumar Swaminathan, +20 authors, NAVIGATE ESUS Investigators.
Lancet Neurol, 2018 Oct 03; 17(12). PMID: 30274772    Free PMC article.
Immediate Antihypertensive Treatment for Patients With Acute Ischemic Stroke With or Without History of Hypertension: A Secondary Analysis of the CATIS Randomized Clinical Trial.
Rui Zhang, Chongke Zhong, +14 authors, Jiang He.
JAMA Netw Open, 2019 Aug 01; 2(7). PMID: 31365109    Free PMC article.
Quality of reporting of systematic reviews and meta-analyses of surgical randomized clinical trials.
J Yu, W Chen, P Wu, Y Li.
BJS Open, 2020 Feb 29; 4(3). PMID: 32109006    Free PMC article.
Doxycycline for exacerbations of chronic obstructive pulmonary disease in outpatients: who benefits?
Patricia van Velzen, Gerben Ter Riet, +2 authors, Jan M Prins.
ERJ Open Res, 2020 Jun 05; 6(2). PMID: 32494571    Free PMC article.
Comparison of Bacterial Load Parameters in Subgingival Plaque during Peri-implantitis and Periodontitis Using the RT-PCR Method.
Oksana Nastych, Myroslav Goncharuk-Khomyn, +3 authors, Vladyslav Tsaryk.
Acta Stomatol Croat, 2020 Jun 12; 54(1). PMID: 32523155    Free PMC article.
Characteristics and interpretation of subgroup analyses based on tumour characteristics in randomised trials testing target-specific anticancer drugs: design of a systematic survey.
Stefan Schandelmaier, Andreas M Schmitt, +6 authors, Benjamin Kasenda.
BMJ Open, 2020 Jun 01; 10(5). PMID: 32474426    Free PMC article.
Efficacy and safety of sarilumab in combination with csDMARDs or as monotherapy in subpopulations of patients with moderately to severely active rheumatoid arthritis in three phase III randomized, controlled studies.
Mark C Genovese, Roy Fleischmann, +6 authors, Gerd R Burmester.
Arthritis Res Ther, 2020 Jun 12; 22(1). PMID: 32522251    Free PMC article.
Is the positive association between middle-income and rich household wealth and adult sub-Saharan African women's overweight status modified by the level of education attainment? A cross-sectional study of 22 countries.
Ifeoma D Ozodiegwu, Henry V Doctor, +3 authors, Hadii M Mamudu.
BMC Public Health, 2020 Jun 27; 20(1). PMID: 32586312    Free PMC article.
Can Statin Treatment Reduce the Risk of Hepatocellular Carcinoma? A Systematic Review and Meta-Analysis.
Yue Chang, Qinyu Liu, +7 authors, Hai Li.
Technol Cancer Res Treat, 2020 Jun 20; 19. PMID: 32552476    Free PMC article.
Effects of dapagliflozin in DAPA-HF according to background heart failure therapy.
Kieran F Docherty, Pardeep S Jhund, +21 authors, John J V McMurray.
Eur Heart J, 2020 Mar 30; 41(25). PMID: 32221582    Free PMC article.
Adjuvant Systemic Chemotherapy vs Active Surveillance Following Up-front Resection of Isolated Synchronous Colorectal Peritoneal Metastases.
Koen P Rovers, Checca Bakkers, +9 authors, Ignace H J T de Hingh.
JAMA Oncol, 2020 Jul 17; 6(8). PMID: 32672798    Free PMC article.
A Patient-Centered Approach to Comparative Effectiveness Research Focused on Older Adults: Lessons From the Patient-Centered Outcomes Research Institute.
Noah R Mason, Harold C Sox, Evelyn P Whitlock.
J Am Geriatr Soc, 2018 Dec 27; 67(1). PMID: 30586155    Free PMC article.
Comparison of protocols and registry entries to published reports for randomised controlled trials.
Kerry Dwan, Douglas G Altman, +3 authors, Paula R Williamson.
Cochrane Database Syst Rev, 2011 Jan 21; (1). PMID: 21249714    Free PMC article.
Highly Cited.
NICE and Fair? Health Technology Assessment Policy Under the UK's National Institute for Health and Care Excellence, 1999-2018.
Victoria Charlton.
Health Care Anal, 2019 Jul 22; 28(3). PMID: 31325000    Free PMC article.
Searching for the Backfire Effect: Measurement and Design Considerations.
Briony Swire-Thompson, Joseph DeGutis, David Lazer.
J Appl Res Mem Cogn, 2020 Sep 10; 9(3). PMID: 32905023    Free PMC article.
Review.
Pregnancy outcomes among women born in Somalia and Sweden giving birth in the Stockholm area - a population-based study.
Anna Akselsson, Helena Lindgren, +3 authors, Ingela Rådestad.
Glob Health Action, 2020 Aug 04; 13(1). PMID: 32744184    Free PMC article.
Intensity and duration of lifestyle interventions for long-term weight loss and association with mortality: a meta-analysis of randomised trials.
Navneet Singh, Ralph Alan Huston Stewart, Jocelyne Rachelle Benatar.
BMJ Open, 2019 Aug 21; 9(8). PMID: 31427335    Free PMC article.
Group Cohesion and Climate in Cognitive Behavioral Therapy for Individuals with a First-Time DUI.
Maricela Cruz, Karen Chan Osilla, Susan M Paddock.
Alcohol Treat Q, 2020 Sep 22; 38(1). PMID: 32952283    Free PMC article.
The impact of particulate matter 2.5 on the risk of preeclampsia: an updated systematic review and meta-analysis.
Hongbiao Yu, Yangxue Yin, Jiashuo Zhang, Rong Zhou.
Environ Sci Pollut Res Int, 2020 Aug 03; 27(30). PMID: 32740838    Free PMC article.
Systematic Review.
Mifepristone and misoprostol versus misoprostol alone for the management of missed miscarriage (MifeMiso): a randomised, double-blind, placebo-controlled trial.
Justin J Chu, Adam J Devall, +37 authors, Arri Coomarasamy.
Lancet, 2020 Aug 28; 396(10253). PMID: 32853559    Free PMC article.
The Predictive Approaches to Treatment effect Heterogeneity (PATH) Statement.
David M Kent, Jessica K Paulus, +14 authors, Ewout W Steyerberg.
Ann Intern Med, 2019 Nov 12; 172(1). PMID: 31711134    Free PMC article.
Exudative Retinal Detachment in Ocular Inflammatory Diseases: Risk and Predictive Factors.
Deepika N Shah, Ahmad Al-Moujahed, +13 authors, Systemic Immunosuppressive Therapy for Eye Diseases Research Group.
Am J Ophthalmol, 2020 Jul 06; 218. PMID: 32621891    Free PMC article.
Clinical and cost-effectiveness of vaginal pessary self-management compared to clinic-based care for pelvic organ prolapse: protocol for the TOPSY randomised controlled trial.
Suzanne Hagen, Rohna Kearney, +19 authors, Carol Bugge.
Trials, 2020 Oct 10; 21(1). PMID: 33032644    Free PMC article.
Vitamin D Supplementation for Prevention of Type 2 Diabetes Mellitus: To D or Not to D?
Anastassios G Pittas, Rolf Jorde, Tetsuya Kawahara, Bess Dawson-Hughes.
J Clin Endocrinol Metab, 2020 Aug 28; 105(12). PMID: 32844212    Free PMC article.
Clinical Endpoints for Evaluating Efficacy in COVID-19 Vaccine Trials.
Devan V Mehrotra, Holly E Janes, +25 authors, Peter B Gilbert.
Ann Intern Med, 2020 Oct 23;. PMID: 33090877    Free PMC article.
Maternal Arsenic Exposure and Gestational Diabetes: A Systematic Review and Meta-Analysis.
Noemi Salmeri, Roberta Villanacci, +8 authors, Massimo Candiani.
Nutrients, 2020 Oct 15; 12(10). PMID: 33050632    Free PMC article.
Review.
Renin, Angiotensin II, and the Journey to Evidence-based Individual Treatment Effects.
Jonathan D Casey, Matthew W Semler.
Am J Respir Crit Care Med, 2020 Aug 05; 202(9). PMID: 32749864    Free PMC article.
Equivalency between the shock index and subtracting the systolic blood pressure from the heart rate: an observational cohort study.
Yohei Kamikawa, Hiroyuki Hayashi.
BMC Emerg Med, 2020 Nov 02; 20(1). PMID: 33129277    Free PMC article.
First-line support for assistance in breathing in children: statistical and health economic analysis plan for the FIRST-ABC trial.
Izabella Orzechowska, M Zia Sadique, +8 authors, David A Harrison.
Trials, 2020 Nov 02; 21(1). PMID: 33129360    Free PMC article.
Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial.
Wesley H Self, Matthew W Semler, +31 authors, National Heart, Lung, and Blood Institute PETAL Clinical Trials Network.
JAMA, 2020 Nov 10; 324(21). PMID: 33165621    Free PMC article.