Role of dendritic cells in antibody-dependent enhancement of dengue virus infection.
Kobporn Boonnak, Bonnie M Slike, +8 authors, Timothy H Burgess, Randall M Mason, Shuenn-Jue Wu, Peifang Sun, Kevin Porter, Irani Fianza Rudiman, Djoko Yuwono, Pilaipan Puthavathana, Mary A Marovich. less
J Virol, 2008 Feb 15; 82(8). PMID: 18272578 Free PMC article.
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Making autoantibodies safe.
Christopher N Scanlan, Dennis R Burton, Raymond A Dwek.
Proc Natl Acad Sci U S A, 2008 Mar 18; 105(11). PMID: 18344326 Free PMC article.
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Distinct cell-specific control of autoimmunity and infection by FcgammaRIIb.
Rebecca J Brownlie, Kate E Lawlor, +7 authors, Heather A Niederer, Antony J Cutler, Zou Xiang, Menna R Clatworthy, R Andres Floto, David R Greaves, Paul A Lyons, Kenneth G C Smith. less
J Exp Med, 2008 Mar 26; 205(4). PMID: 18362174 Free PMC article.
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Inhalation of Francisella novicida Delta mglA causes replicative infection that elicits innate and adaptive responses but is not protective against invasive pneumonic tularemia.
T Eoin West, Mark R Pelletier, +3 authors, Melanie C Majure, Annalisa Lembo, Adeline M Hajjar, Shawn J Skerrett. less
Microbes Infect, 2008 Jun 10; 10(7). PMID: 18539500 Free PMC article.
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Role of chaperones and FcgammaR in immunogenic death.
Madhav V Dhodapkar, Kavita M Dhodapkar, Zihai Li.
Curr Opin Immunol, 2008 Jun 24; 20(5). PMID: 18572395 Free PMC article.
Review.
|
Phagocytic signaling: you can touch, but you can't eat.
Jason M Kinchen, Kodi S Ravichandran.
Curr Biol, 2008 Jun 27; 18(12). PMID: 18579095 Free PMC article.
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The crystal structure of CHIR-AB1: a primordial avian classical Fc receptor.
Tal I Arnon, Jens T Kaiser, +5 authors, Anthony P West, Rich Olson, Ron Diskin, Birgit C Viertlboeck, Thomas W Göbel, Pamela J Bjorkman. less
J Mol Biol, 2008 Jul 16; 381(4). PMID: 18625238 Free PMC article.
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Fc receptor engagement mediates differentiation of cardiac fibroblast precursor cells.
Sandra B Haudek, JoAnn Trial, +3 authors, Ying Xia, Damon Gupta, Darrell Pilling, Mark L Entman. less
Proc Natl Acad Sci U S A, 2008 Jul 18; 105(29). PMID: 18632582 Free PMC article.
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Neuroprotection in stroke by complement inhibition and immunoglobulin therapy.
T V Arumugam, T M Woodruff, +3 authors, J D Lathia, P K Selvaraj, M P Mattson, S M Taylor. less
Neuroscience, 2008 Aug 12; 158(3). PMID: 18691639 Free PMC article.
Review.
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Potential therapy of Fc-antigen combination-encoding DNA vaccination in mouse allergic airway inflammation.
Y Wang, G Qian, +3 authors, G Wang, X Cheng, C Bai, X Wang. less
Clin Exp Immunol, 2008 Aug 30; 154(1). PMID: 18727625 Free PMC article.
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Negative signaling by inhibitory receptors: the NK cell paradigm.
Eric O Long.
Immunol Rev, 2008 Sep 02; 224. PMID: 18759921 Free PMC article.
Highly Cited. Review.
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Role of B cells in systemic lupus erythematosus and rheumatoid arthritis.
Laura Mandik-Nayak, Natalie Ridge, +2 authors, Michele Fields, Audrey Y Park, Jan Erikson. less
Curr Opin Immunol, 2008 Sep 09; 20(6). PMID: 18775493 Free PMC article.
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Structural insights into the mechanisms of antibody-mediated neutralization of flavivirus infection: implications for vaccine development.
Theodore C Pierson, Daved H Fremont, Richard J Kuhn, Michael S Diamond.
Cell Host Microbe, 2008 Sep 10; 4(3). PMID: 18779049 Free PMC article.
Highly Cited. Review.
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A signal-switch hypothesis for cross-regulation of cytokine and TLR signalling pathways.
Lionel B Ivashkiv.
Nat Rev Immunol, 2008 Sep 13; 8(10). PMID: 18787561 Free PMC article.
Review.
|
Antibodies against a surface protein of Streptococcus pyogenes promote a pathological inflammatory response.
Fredrik Kahn, Matthias Mörgelin, +4 authors, Oonagh Shannon, Anna Norrby-Teglund, Heiko Herwald, Anders I Olin, Lars Björck. less
PLoS Pathog, 2008 Sep 13; 4(9). PMID: 18787689 Free PMC article.
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Immune modulating effect by a phosphoprotein-deleted rabies virus vaccine vector expressing two copies of the rabies virus glycoprotein gene.
Jonathan Cenna, Gene S Tan, +3 authors, Amy B Papaneri, Bernhard Dietzschold, Matthias J Schnell, James P McGettigan. less
Vaccine, 2008 Sep 23; 26(50). PMID: 18804506 Free PMC article.
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In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner.
Heike Albert, Mattias Collin, +2 authors, Diana Dudziak, Jeffrey V Ravetch, Falk Nimmerjahn. less
Proc Natl Acad Sci U S A, 2008 Sep 26; 105(39). PMID: 18815375 Free PMC article.
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Blockade of maternal anti-HPA-1a-mediated platelet clearance by an HPA-1a epitope-specific F(ab') in an in vivo mouse model of alloimmune thrombocytopenia.
Tamam Bakchoul, Brian Boylan, +4 authors, Ulrich J H Sachs, Gregor Bein, Changgeng Ruan, Sentot Santoso, Peter J Newman. less
Transfusion, 2008 Nov 13; 49(2). PMID: 19000229 Free PMC article.
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Identification of a receptor required for the anti-inflammatory activity of IVIG.
Robert M Anthony, Fredrik Wermeling, Mikael C I Karlsson, Jeffrey V Ravetch.
Proc Natl Acad Sci U S A, 2008 Nov 28; 105(50). PMID: 19036920 Free PMC article.
Highly Cited.
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Improved tumor immunity using anti-tyrosinase related protein-1 monoclonal antibody combined with DNA vaccines in murine melanoma.
Yvonne M Saenger, Yanyun Li, +6 authors, Karoline C Chiou, Brian Chan, Gabrielle Rizzuto, Stephanie L Terzulli, Taha Merghoub, Alan N Houghton, Jedd D Wolchok. less
Cancer Res, 2008 Dec 03; 68(23). PMID: 19047169 Free PMC article.
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Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies.
Angela Giorgini, Heather J Brown, +5 authors, Helen R Lock, Falk Nimmerjahn, Jeffrey V Ravetch, J Sjef Verbeek, Steven H Sacks, Michael G Robson. less
J Immunol, 2008 Dec 04; 181(12). PMID: 19050295 Free PMC article.
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Aglycosylated immunoglobulin G1 variants productively engage activating Fc receptors.
Stephen L Sazinsky, René G Ott, +3 authors, Nathaniel W Silver, Bruce Tidor, Jeffrey V Ravetch, K Dane Wittrup. less
Proc Natl Acad Sci U S A, 2008 Dec 17; 105(51). PMID: 19074274 Free PMC article.
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Immunoglobulin G subclass-specific responses against Plasmodium falciparum merozoite antigens are associated with control of parasitemia and protection from symptomatic illness.
Danielle I Stanisic, Jack S Richards, +8 authors, Fiona J McCallum, Pascal Michon, Christopher L King, Sonja Schoepflin, Paul R Gilson, Vincent J Murphy, Robin F Anders, Ivo Mueller, James G Beeson. less
Infect Immun, 2009 Jan 14; 77(3). PMID: 19139189 Free PMC article.
Highly Cited.
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An integrated approach for measuring copy number variation at the FCGR3 (CD16) locus.
Edward J Hollox, Jan-Christoph Detering, Tushna Dehnugara.
Hum Mutat, 2009 Jan 15; 30(3). PMID: 19143032 Free PMC article.
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When is a malaria immune complex not an immune complex?
R J Pleass.
Parasite Immunol, 2009 Jan 20; 31(2). PMID: 19149773 Free PMC article.
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Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis.
Yuntao S Mao, Masaki Yamaga, +12 authors, Xiaohui Zhu, Yongjie Wei, Hui-Qiao Sun, Jing Wang, Mia Yun, Yanfeng Wang, Gilbert Di Paolo, Michael Bennett, Ira Mellman, Charles S Abrams, Pietro De Camilli, Christopher Y Lu, Helen L Yin. less
J Cell Biol, 2009 Jan 21; 184(2). PMID: 19153220 Free PMC article.
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Macrophages activated by C-reactive protein through Fc gamma RI transfer suppression of immune thrombocytopenia.
Kristopher D Marjon, Lorraine L Marnell, Carolyn Mold, Terry W Du Clos.
J Immunol, 2009 Jan 22; 182(3). PMID: 19155486 Free PMC article.
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Efficacy of opsonic and nonopsonic serotype 3 pneumococcal capsular polysaccharide-specific monoclonal antibodies against intranasal challenge with Streptococcus pneumoniae in mice.
Haijun Tian, Sarah Weber, +2 authors, Peter Thorkildson, Thomas R Kozel, Liise-Anne Pirofski. less
Infect Immun, 2009 Jan 27; 77(4). PMID: 19168739 Free PMC article.
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Glycosylation as a strategy to improve antibody-based therapeutics.
Roy Jefferis.
Nat Rev Drug Discov, 2009 Feb 28; 8(3). PMID: 19247305
Highly Cited. Review.
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Impaired inhibitory Fcgamma receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy.
Björn Tackenberg, Ilijas Jelcic, +4 authors, Anne Baerenwaldt, Wolfgang H Oertel, Norbert Sommer, Falk Nimmerjahn, Jan D Lünemann. less
Proc Natl Acad Sci U S A, 2009 Mar 06; 106(12). PMID: 19261857 Free PMC article.
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Proteomics-based identification of anchorless cell wall proteins as vaccine candidates against Staphylococcus aureus.
Eva Glowalla, Bettina Tosetti, Martin Krönke, Oleg Krut.
Infect Immun, 2009 Apr 15; 77(7). PMID: 19364833 Free PMC article.
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Fcgamma receptors: structure, function and role as genetic risk factors in SLE.
X Li, T S Ptacek, E E Brown, J C Edberg.
Genes Immun, 2009 May 08; 10(5). PMID: 19421223 Free PMC article.
Review.
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Antibody-mediated immunity to the obligate intracellular bacterial pathogen Coxiella burnetii is Fc receptor- and complement-independent.
Jeffrey G Shannon, Diane C Cockrell, +2 authors, Kazue Takahashi, Gregory L Stahl, Robert A Heinzen. less
BMC Immunol, 2009 May 12; 10. PMID: 19426498 Free PMC article.
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Utilization of immunoglobulin G Fc receptors by human immunodeficiency virus type 1: a specific role for antibodies against the membrane-proximal external region of gp41.
Lautaro G Perez, Matthew R Costa, +2 authors, Christopher A Todd, Barton F Haynes, David C Montefiori. less
J Virol, 2009 May 22; 83(15). PMID: 19458010 Free PMC article.
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Cross-talk between TLR4 and FcgammaReceptorIII (CD16) pathways.
Daniel Rittirsch, Michael A Flierl, +8 authors, Danielle E Day, Brian A Nadeau, Firas S Zetoune, J Vidya Sarma, Clement M Werner, Guido A Wanner, Hans-Peter Simmen, Markus S Huber-Lang, Peter A Ward. less
PLoS Pathog, 2009 Jun 09; 5(6). PMID: 19503602 Free PMC article.
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Characterization and ligand specificity of sheep IgG2 receptor.
Songlin Qiao, Yanyan Yang, +7 authors, Yunchao Liu, Gaiping Zhang, Jun Xi, Hong Zhang, Huifang Hao, Xiaohui Tian, Suzhen Yang, Ruiguang Deng. less
Immunogenetics, 2009 Jul 10; 61(8). PMID: 19588135
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Functional and clinical consequences of Fc receptor polymorphic and copy number variants.
S Bournazos, J M Woof, S P Hart, I Dransfield.
Clin Exp Immunol, 2009 Jul 17; 157(2). PMID: 19604264 Free PMC article.
Review.
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Antibody limits in vivo murid herpesvirus-4 replication by IgG Fc receptor-dependent functions.
Debbie E Wright, Susanna Colaco, Camilo Colaco, Philip G Stevenson.
J Gen Virol, 2009 Jul 25; 90(Pt 11). PMID: 19625459 Free PMC article.
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Activation of Fc gamma RI on monocytes triggers differentiation into immature dendritic cells that induce autoreactive T cell responses.
Motoyuki Tanaka, Stephan R Krutzik, +3 authors, Peter A Sieling, Delphine J Lee, Thomas H Rea, Robert L Modlin. less
J Immunol, 2009 Jul 29; 183(4). PMID: 19635920 Free PMC article.
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Analysis of the Fc gamma receptor-dependent component of neutralization measured by anthrax toxin neutralization assays.
Anita Verma, Miriam M Ngundi, +3 authors, Bruce D Meade, Roberto De Pascalis, Karen L Elkins, Drusilla L Burns. less
Clin Vaccine Immunol, 2009 Aug 07; 16(10). PMID: 19656993 Free PMC article.
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Displaying Fel d1 on virus-like particles prevents reactogenicity despite greatly enhanced immunogenicity: a novel therapy for cat allergy.
Nicole Schmitz, Klaus Dietmeier, +5 authors, Monika Bauer, Melanie Maudrich, Stefan Utzinger, Simone Muntwiler, Philippe Saudan, Martin F Bachmann. less
J Exp Med, 2009 Aug 12; 206(9). PMID: 19667059 Free PMC article.
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Fc-receptors and immunity to malaria: from models to vaccines.
R J Pleass.
Parasite Immunol, 2009 Aug 21; 31(9). PMID: 19691552 Free PMC article.
Review.
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Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites.
Alexander I Taylor, Brian J Sutton, Rosaleen A Calvert.
Dev Comp Immunol, 2009 Sep 08; 34(2). PMID: 19733585 Free PMC article.
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The state of the art: immune-mediated mechanisms of monoclonal antibodies in cancer therapy.
J Griggs, K Zinkewich-Peotti.
Br J Cancer, 2009 Oct 08; 101(11). PMID: 19809433 Free PMC article.
Review.
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Tumor-associated and microbial proteases compromise host IgG effector functions by a single cleavage proximal to the hinge.
Randall J Brezski, Omid Vafa, +7 authors, Diane Petrone, Susan H Tam, Gordon Powers, Mary H Ryan, Jennifer L Luongo, Allison Oberholtzer, David M Knight, Robert E Jordan. less
Proc Natl Acad Sci U S A, 2009 Oct 10; 106(42). PMID: 19815504 Free PMC article.
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Dengue virus neutralization is modulated by IgG antibody subclass and Fcgamma receptor subtype.
W W Shanaka I Rodrigo, Olivia K T Block, +8 authors, Christopher Lane, Soila Sukupolvi-Petty, Ana P Goncalvez, Syd Johnson, Michael S Diamond, Ching-Juh Lai, Robert C Rose, Xia Jin, Jacob J Schlesinger. less
Virology, 2009 Oct 17; 394(2). PMID: 19833371 Free PMC article.
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Complement protein C1q reduces the stoichiometric threshold for antibody-mediated neutralization of West Nile virus.
Erin Mehlhop, Steevenson Nelson, +5 authors, Christiane A Jost, Sergey Gorlatov, Syd Johnson, Daved H Fremont, Michael S Diamond, Theodore C Pierson. less
Cell Host Microbe, 2009 Oct 20; 6(4). PMID: 19837377 Free PMC article.
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Involvement of Fc receptors in disorders of the central nervous system.
Eitan Okun, Mark P Mattson, Thiruma V Arumugam.
Neuromolecular Med, 2009 Oct 22; 12(2). PMID: 19844812 Free PMC article.
Review.
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Identity of the elusive IgM Fc receptor (FcmuR) in humans.
Hiromi Kubagawa, Satoshi Oka, +10 authors, Yoshiki Kubagawa, Ikuko Torii, Eiji Takayama, Dong-Won Kang, G Larry Gartland, Luigi F Bertoli, Hiromi Mori, Hiroyuki Takatsu, Toshio Kitamura, Hiroshi Ohno, Ji-Yang Wang. less
J Exp Med, 2009 Oct 28; 206(12). PMID: 19858324 Free PMC article.
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Molecularly defined antibody conjugation through a selenocysteine interface.
Thomas Hofer, Lauren R Skeffington, Colby M Chapman, Christoph Rader.
Biochemistry, 2009 Nov 10; 48(50). PMID: 19894757 Free PMC article.
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The expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells.
Jessica A Hamerman, Minjian Ni, +2 authors, Justin R Killebrew, Ching-Liang Chu, Clifford A Lowell. less
Immunol Rev, 2009 Nov 17; 232(1). PMID: 19909355 Free PMC article.
Review.
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Mechanisms of immune complex-mediated neutrophil recruitment and tissue injury.
Tanya N Mayadas, George C Tsokos, Naotake Tsuboi.
Circulation, 2009 Nov 18; 120(20). PMID: 19917895 Free PMC article.
Review.
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Tissue-mediated control of immunopathology in coeliac disease.
Bana Jabri, Ludvig M Sollid.
Nat Rev Immunol, 2009 Nov 26; 9(12). PMID: 19935805
Highly Cited. Review.
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Murine IgG1 and IgG3 isotype switch variants promote phagocytosis of Cryptococcus neoformans through different receptors.
Carolyn A Saylor, Ekaterina Dadachova, Arturo Casadevall.
J Immunol, 2009 Dec 02; 184(1). PMID: 19949107 Free PMC article.
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The other side of immunoglobulin G: suppressor of inflammation.
S Aschermann, A Lux, +2 authors, A Baerenwaldt, M Biburger, F Nimmerjahn. less
Clin Exp Immunol, 2010 Jan 01; 160(2). PMID: 20041883 Free PMC article.
Review.
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A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis.
Joana Rf Abreu, Wendy Dontje, +9 authors, Sarah Krausz, Daphne de Launay, Paula B van Hennik, Anne-Marieke van Stalborch, Jean-Paul Ten Klooster, Marjolein E Sanders, Kris A Reedquist, Margriet J Vervoordeldonk, Peter L Hordijk, Paul P Tak. less
Arthritis Res Ther, 2010 Jan 08; 12(1). PMID: 20053277 Free PMC article.
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Antibodies to wounded tissue enhance cutaneous wound healing.
Naomi Nishio, Sachiko Ito, Haruhiko Suzuki, Ken-ichi Isobe.
Immunology, 2010 Jan 14; 128(3). PMID: 20067537 Free PMC article.
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IgG2m4, an engineered antibody isotype with reduced Fc function.
Zhiqiang An, Gail Forrest, +13 authors, Renee Moore, Michael Cukan, Peter Haytko, Lingyi Huang, Salvatore Vitelli, Jing Zhang Zhao, Ping Lu, Jin Hua, Christopher R Gibson, Barrett R Harvey, Donna Montgomery, Dennis Zaller, Fubao Wang, William Strohl. less
MAbs, 2010 Jan 16; 1(6). PMID: 20073128 Free PMC article.
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Aglycosylated IgG variants expressed in bacteria that selectively bind FcgammaRI potentiate tumor cell killing by monocyte-dendritic cells.
Sang Taek Jung, Sai T Reddy, +4 authors, Tae Hyun Kang, M Jack Borrok, Inger Sandlie, Philip W Tucker, George Georgiou. less
Proc Natl Acad Sci U S A, 2010 Jan 19; 107(2). PMID: 20080725 Free PMC article.
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Antigen-induced oligomerization of the B cell receptor is an early target of Fc gamma RIIB inhibition.
Wanli Liu, Hae Won Sohn, +2 authors, Pavel Tolar, Tobias Meckel, Susan K Pierce. less
J Immunol, 2010 Jan 20; 184(4). PMID: 20083655 Free PMC article.
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Does activation of the FcgammaRIIa play a role in the pathogenesis of the acute lung injury/acute respiratory distress syndrome?
Rafal Fudala, Agnieszka Krupa, +2 authors, Dorota Stankowska, Timothy C Allen, Anna K Kurdowska. less
Clin Sci (Lond), 2010 Jan 22; 118(8). PMID: 20088831 Free PMC article.
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Mechanisms involved in antibody- and complement-mediated allograft rejection.
Barbara A Wasowska.
Immunol Res, 2010 Feb 06; 47(1-3). PMID: 20135240 Free PMC article.
Review.
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FcRgamma activation regulates inflammation-associated squamous carcinogenesis.
Pauline Andreu, Magnus Johansson, +11 authors, Nesrine I Affara, Ferdinando Pucci, Tingting Tan, Simon Junankar, Lidiya Korets, Julia Lam, David Tawfik, David G DeNardo, Luigi Naldini, Karin E de Visser, Michele De Palma, Lisa M Coussens. less
Cancer Cell, 2010 Feb 09; 17(2). PMID: 20138013 Free PMC article.
Highly Cited.
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In vivo veritas: the surprising roles of Fc receptors in immunity.
Jeffrey Ravetch.
Nat Immunol, 2010 Feb 17; 11(3). PMID: 20157296
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The neonatal Fc receptor as therapeutic target in IgG-mediated autoimmune diseases.
Alina Sesarman, Gestur Vidarsson, Cassian Sitaru.
Cell Mol Life Sci, 2010 Mar 11; 67(15). PMID: 20217455
Review.
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Fcgamma receptors modulate pulmonary inflammation by activating innate immune cells in murine hypersensitivity pneumonitis.
Hyo Jin Park, Hye Sung Kim, Doo Hyun Chung.
Immune Netw, 2010 Mar 17; 10(1). PMID: 20228933 Free PMC article.
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Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones.
Isabelle Isnardi, Yen-Shing Ng, +8 authors, Laurence Menard, Greta Meyers, David Saadoun, Iva Srdanovic, Jonathan Samuels, Jessica Berman, Jane H Buckner, Charlotte Cunningham-Rundles, Eric Meffre. less
Blood, 2010 Mar 17; 115(24). PMID: 20231422 Free PMC article.
Highly Cited.
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Intravenous immunoglobulins as a treatment for Alzheimer's disease: rationale and current evidence.
Richard Dodel, Frauke Neff, +4 authors, Carmen Noelker, Refik Pul, Yansheng Du, Michael Bacher, Wolfgang Oertel. less
Drugs, 2010 Mar 25; 70(5). PMID: 20329802
Review.
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Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins.
Lu Wang, Rachael A Gordon, +6 authors, Linda Huynh, Xiaodi Su, Kyung-Hyun Park Min, Jiahuai Han, J Simon Arthur, George D Kalliolias, Lionel B Ivashkiv. less
Immunity, 2010 Apr 07; 32(4). PMID: 20362473 Free PMC article.
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B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcgammaRIIb, which are modulated by anti-tumor necrosis factor therapy.
Diego Catalán, Octavio Aravena, +6 authors, Francisca Sabugo, Pamela Wurmann, Lilian Soto, Alexis M Kalergis, Miguel Cuchacovich, Juan C Aguillón, Millenium Nucleus on Immunology and Immunotherapy P-07-088-F. less
Arthritis Res Ther, 2010 Apr 20; 12(2). PMID: 20398308 Free PMC article.
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Cleavage of IgGs by proteases associated with invasive diseases: an evasion tactic against host immunity?
Randall J Brezski, Robert E Jordan.
MAbs, 2010 Apr 20; 2(3). PMID: 20400859 Free PMC article.
Review.
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FcgammaRIIB in autoimmunity and infection: evolutionary and therapeutic implications.
Kenneth G C Smith, Menna R Clatworthy.
Nat Rev Immunol, 2010 Apr 24; 10(5). PMID: 20414206 Free PMC article.
Highly Cited. Review.
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Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies.
Frank R Brennan, Laura Dill Morton, +6 authors, Sebastian Spindeldreher, Andrea Kiessling, Roy Allenspach, Adam Hey, Patrick Y Muller, Werner Frings, Jennifer Sims. less
MAbs, 2010 Apr 28; 2(3). PMID: 20421713 Free PMC article.
Review.
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Mechanisms of IVIG efficacy in chronic inflammatory demyelinating polyneuropathy.
Björn Tackenberg, Falk Nimmerjahn, Jan D Lünemann.
J Clin Immunol, 2010 Apr 29; 30 Suppl 1. PMID: 20424898
Review.
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Genetics of SLE: evidence from mouse models.
Laurence Morel.
Nat Rev Rheumatol, 2010 May 05; 6(6). PMID: 20440287
Review.
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IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis.
Mirjan M van Timmeren, Betty S van der Veen, +4 authors, Coen A Stegeman, Arjen H Petersen, Thomas Hellmark, Mattias Collin, Peter Heeringa. less
J Am Soc Nephrol, 2010 May 08; 21(7). PMID: 20448018 Free PMC article.
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Monocyte surface expression of Fcgamma receptor RI (CD64), a biomarker reflecting type-I interferon levels in systemic lupus erythematosus.
Yi Li, Pui Y Lee, +8 authors, Erinn S Kellner, Matthew Paulus, Juliana Switanek, Yuan Xu, Haoyang Zhuang, Eric S Sobel, Mark S Segal, Minoru Satoh, Westley H Reeves. less
Arthritis Res Ther, 2010 May 19; 12(3). PMID: 20478071 Free PMC article.
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A novel role for the IgG Fc glycan: the anti-inflammatory activity of sialylated IgG Fcs.
Robert M Anthony, Jeffrey V Ravetch.
J Clin Immunol, 2010 May 19; 30 Suppl 1. PMID: 20480216
Highly Cited. Review.
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Copy number, linkage disequilibrium and disease association in the FCGR locus.
Heather A Niederer, Lisa C Willcocks, +17 authors, Tim F Rayner, Wanling Yang, Yu Lung Lau, Thomas N Williams, J Anthony G Scott, Britta C Urban, Norbert Peshu, Sarah J Dunstan, Tran Tinh Hien, Nguyen Hoan Phu, Leonid Padyukov, Iva Gunnarsson, Elisabet Svenungsson, Caroline O Savage, Richard A Watts, Paul A Lyons, David G Clayton, Kenneth G C Smith. less
Hum Mol Genet, 2010 May 29; 19(16). PMID: 20508037 Free PMC article.
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Cutting edge: FcR-like 6 is an MHC class II receptor.
Daniel M Schreeder, John P Cannon, +3 authors, Jiongru Wu, Ran Li, Mikhail A Shakhmatov, Randall S Davis. less
J Immunol, 2010 Jun 04; 185(1). PMID: 20519654 Free PMC article.
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EB66 cell line, a duck embryonic stem cell-derived substrate for the industrial production of therapeutic monoclonal antibodies with enhanced ADCC activity.
Stéphane Olivier, Marine Jacoby, +12 authors, Cédric Brillon, Sylvana Bouletreau, Thomas Mollet, Olivier Nerriere, Audrey Angel, Sévérine Danet, Boussad Souttou, Fabienne Guehenneux, Laurent Gauthier, Mathilde Berthomé, Henri Vié, Nicola Beltraminelli, Majid Mehtali. less
MAbs, 2010 Jun 22; 2(4). PMID: 20562528 Free PMC article.
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Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response.
Cristina L Swanson, Timothy J Wilson, +3 authors, Pamela Strauch, Marco Colonna, Roberta Pelanda, Raul M Torres. less
J Exp Med, 2010 Jun 23; 207(7). PMID: 20566717 Free PMC article.
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Functional expression of IgG-Fc receptors in human airway smooth muscle cells.
YuXiu C Xia, Michael Schuliga, +8 authors, Malcolm Shepherd, Maree Powell, Trudi Harris, Shenna Y Langenbach, Peck Szee Tan, William T Gerthoffer, P Mark Hogarth, Alastair G Stewart, Graham A Mackay. less
Am J Respir Cell Mol Biol, 2010 Jul 03; 44(5). PMID: 20595464 Free PMC article.
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Long-lasting protective antiviral immunity induced by passive immunotherapies requires both neutralizing and effector functions of the administered monoclonal antibody.
Roudaina Nasser, Mireia Pelegrin, +3 authors, Henri-Alexandre Michaud, Marc Plays, Marc Piechaczyk, Laurent Gros. less
J Virol, 2010 Jul 09; 84(19). PMID: 20610721 Free PMC article.
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ITAM signaling in dendritic cells controls T helper cell priming by regulating MHC class II recycling.
Daniel B Graham, Holly M Akilesh, +13 authors, Grzegorz B Gmyrek, Laura Piccio, Susan Gilfillan, Julia Sim, Roger Belizaire, Javier A Carrero, Yinan Wang, Gregory S Blaufuss, Gabriel Sandoval, Keiko Fujikawa, Anne H Cross, John H Russell, Marina Cella, Wojciech Swat. less
Blood, 2010 Jul 17; 116(17). PMID: 20634378 Free PMC article.
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SIVsm Tat, Rev, and Nef1: functional characteristics of r-GV internalization on isotypes, cytokines, and intracellular degradation.
Marinko Sremac, Elizabeth S Stuart.
BMC Biotechnol, 2010 Jul 21; 10. PMID: 20642814 Free PMC article.
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Programming dendritic cells to induce T(H)2 and tolerogenic responses.
Bali Pulendran, Hua Tang, Santhakumar Manicassamy.
Nat Immunol, 2010 Jul 21; 11(8). PMID: 20644570
Highly Cited. Review.
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Monocyte and macrophage abnormalities in systemic lupus erythematosus.
Yi Li, Pui Y Lee, Westley H Reeves.
Arch Immunol Ther Exp (Warsz), 2010 Aug 03; 58(5). PMID: 20676786 Free PMC article.
Review.
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Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates.
Christopher Sundling, Mattias N E Forsell, +8 authors, Sijy O'Dell, Yu Feng, Bimal Chakrabarti, Srinivas S Rao, Karin Loré, John R Mascola, Richard T Wyatt, Iyadh Douagi, Gunilla B Karlsson Hedestam. less
J Exp Med, 2010 Aug 04; 207(9). PMID: 20679401 Free PMC article.
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Circadian variations in gene expression in rat abdominal adipose tissue and relationship to physiology.
Siddharth Sukumaran, Bai Xue, +2 authors, William J Jusko, Debra C Dubois, Richard R Almon. less
Physiol Genomics, 2010 Aug 05; 42A(2). PMID: 20682845 Free PMC article.
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Alport alloantibodies but not Goodpasture autoantibodies induce murine glomerulonephritis: protection by quinary crosslinks locking cryptic α3(IV) collagen autoepitopes in vivo.
Wentian Luo, Xu-Ping Wang, Clifford E Kashtan, Dorin-Bogdan Borza.
J Immunol, 2010 Aug 17; 185(6). PMID: 20709951 Free PMC article.
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Could the expression of CD86 and FcγRIIB on B cells be functionally related and involved in driving rheumatoid arthritis?
Claudia Mauri, Elizabeth C Jury.
Arthritis Res Ther, 2010 Aug 26; 12(4). PMID: 20735866 Free PMC article.
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Divergent intracellular sorting of Fc{gamma}RIIA and Fc{gamma}RIIB2.
Christine Y Zhang, James W Booth.
J Biol Chem, 2010 Aug 26; 285(44). PMID: 20736173 Free PMC article.
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PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils.
Karen E Anderson, Tamara A M Chessa, +9 authors, Keith Davidson, Robert B Henderson, Simon Walker, Tanya Tolmachova, Katarzyna Grys, Oliver Rausch, Miguel C Seabra, Victor L J Tybulewicz, Len R Stephens, Phillip T Hawkins. less
Blood, 2010 Sep 04; 116(23). PMID: 20813901 Free PMC article.
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The humoral response to HIV-1: new insights, renewed focus.
Galit Alter, M Anthony Moody.
J Infect Dis, 2010 Sep 25; 202 Suppl 2. PMID: 20846039 Free PMC article.
Review.
|
Heat shock protein 70 is acute phase reactant: response elicited by tumor treatment with photodynamic therapy.
Soroush Merchant, Mladen Korbelik.
Cell Stress Chaperones, 2010 Sep 25; 16(2). PMID: 20865355 Free PMC article.
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Defining the immunological phenotype of Fc receptor-like B (FCRLB) deficient mice: Confounding role of the inhibitory FcγRIIb.
Keiji Masuda, Hiromi Mori, +3 authors, Osamu Ohara, Manabu Nakayama, Ji-Yang Wang, Peter D Burrows. less
Cell Immunol, 2010 Sep 28; 266(1). PMID: 20869045 Free PMC article.
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IκBζ is essential for natural killer cell activation in response to IL-12 and IL-18.
Tohru Miyake, Takashi Satoh, +7 authors, Hiroki Kato, Kazufumi Matsushita, Yutaro Kumagai, Alexis Vandenbon, Tohru Tani, Tatsushi Muta, Shizuo Akira, Osamu Takeuchi. less
Proc Natl Acad Sci U S A, 2010 Sep 30; 107(41). PMID: 20876105 Free PMC article.
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Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes.
Scott B Halstead, Suresh Mahalingam, +2 authors, Mary A Marovich, Sukathida Ubol, David M Mosser. less
Lancet Infect Dis, 2010 Oct 05; 10(10). PMID: 20883967 Free PMC article.
Highly Cited. Review.
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Infections of people with complement deficiencies and patients who have undergone splenectomy.
Sanjay Ram, Lisa A Lewis, Peter A Rice.
Clin Microbiol Rev, 2010 Oct 12; 23(4). PMID: 20930072 Free PMC article.
Highly Cited. Review.
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The tipping points in the initiation of B cell signalling: how small changes make big differences.
Susan K Pierce, Wanli Liu.
Nat Rev Immunol, 2010 Oct 12; 10(11). PMID: 20935671 Free PMC article.
Review.
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FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo.
Falk Nimmerjahn, Anja Lux, +5 authors, Heike Albert, Melissa Woigk, Christian Lehmann, Diana Dudziak, Patrick Smith, Jeffrey V Ravetch. less
Proc Natl Acad Sci U S A, 2010 Oct 27; 107(45). PMID: 20974962 Free PMC article.
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Deficiency of activating Fcγ-receptors reduces hepatic clearance and deposition of IC and increases CIC levels in mercury-induced autoimmunity.
Klara Martinsson, Thomas Skogh, +3 authors, Seyed Ali Mousavi, Trond Berg, Jan-Ingvar Jönsson, Per Hultman. less
PLoS One, 2010 Oct 27; 5(10). PMID: 20976163 Free PMC article.
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From vaccines to memory and back.
Federica Sallusto, Antonio Lanzavecchia, Koichi Araki, Rafi Ahmed.
Immunity, 2010 Oct 30; 33(4). PMID: 21029957 Free PMC article.
Highly Cited. Review.
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Interaction of two phagocytic host defense systems: Fcγ receptors and complement receptor 3.
Zhen-Yu Huang, Sharon Hunter, +4 authors, Paul Chien, Moo-Kyung Kim, Tae-Hee Han-Kim, Zena K Indik, Alan D Schreiber. less
J Biol Chem, 2010 Nov 04; 286(1). PMID: 21044955 Free PMC article.
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Src-family and Syk kinases in activating and inhibitory pathways in innate immune cells: signaling cross talk.
Clifford A Lowell.
Cold Spring Harb Perspect Biol, 2010 Nov 12; 3(3). PMID: 21068150 Free PMC article.
Review.
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Mechanism of outside-in {alpha}IIb{beta}3-mediated activation of human platelets by the colonizing Bacterium, Streptococcus gordonii.
Ciara Keane, Helen Petersen, +5 authors, Kieran Reynolds, Debra K Newman, Dermot Cox, Howard F Jenkinson, Peter J Newman, Steven W Kerrigan. less
Arterioscler Thromb Vasc Biol, 2010 Nov 13; 30(12). PMID: 21071690 Free PMC article.
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γδ T-cell killing of primary follicular lymphoma cells is dramatically potentiated by GA101, a type II glycoengineered anti-CD20 monoclonal antibody.
Mounia Sabrina Braza, Bernard Klein, Geneviève Fiol, Jean-François Rossi.
Haematologica, 2010 Nov 27; 96(3). PMID: 21109686 Free PMC article.
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Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis.
Julie A Di Paolo, Tao Huang, +28 authors, Mercedesz Balazs, James Barbosa, Kai H Barck, Brandon J Bravo, Richard A D Carano, James Darrow, Douglas R Davies, Laura E DeForge, Lauri Diehl, Ronald Ferrando, Steven L Gallion, Anthony M Giannetti, Peter Gribling, Vincent Hurez, Sarah G Hymowitz, Randall Jones, Jeffrey E Kropf, Wyne P Lee, Patricia M Maciejewski, Scott A Mitchell, Hong Rong, Bart L Staker, J Andrew Whitney, Sherry Yeh, Wendy B Young, Christine Yu, Juan Zhang, Karin Reif, Kevin S Currie. less
Nat Chem Biol, 2010 Nov 30; 7(1). PMID: 21113169
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Human IgG subclasses: in vitro neutralization of and in vivo protection against West Nile virus.
Yvonne Hofmeister, Christina B Planitzer, +5 authors, Maria R Farcet, Wolfgang Teschner, H Arno Butterweck, Alfred Weber, Georg W Holzer, Thomas R Kreil. less
J Virol, 2010 Dec 03; 85(4). PMID: 21123389 Free PMC article.
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Interleukin-15:Interleukin-15 receptor α scaffold for creation of multivalent targeted immune molecules.
Richard L Wong, Bai Liu, +9 authors, Xiaoyun Zhu, Lijing You, Lin Kong, Kai-Ping Han, Hyung-Il Lee, Pierre-Andre Chavaillaz, Moonsoo Jin, Yi Wang, Peter R Rhode, Hing C Wong. less
Protein Eng Des Sel, 2010 Dec 24; 24(4). PMID: 21177283 Free PMC article.
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High affinity allele for the gene of FCGR3A is risk factor for HIV infection and progression.
Bhawna Poonia, Gustavo H Kijak, C David Pauza.
PLoS One, 2010 Dec 29; 5(12). PMID: 21187939 Free PMC article.
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Antibody-mediated neutralization of flaviviruses: a reductionist view.
Kimberly A Dowd, Theodore C Pierson.
Virology, 2011 Jan 25; 411(2). PMID: 21255816 Free PMC article.
Highly Cited. Review.
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Advances in the assessment and control of the effector functions of therapeutic antibodies.
Xu-Rong Jiang, An Song, +7 authors, Svetlana Bergelson, Thomas Arroll, Bhavin Parekh, Kimberly May, Shan Chung, Robert Strouse, Anthony Mire-Sluis, Mark Schenerman. less
Nat Rev Drug Discov, 2011 Feb 02; 10(2). PMID: 21283105
Highly Cited. Review.
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Chemokine receptor CXCR2 mediates bacterial clearance rather than neutrophil recruitment in a murine model of pneumonic plague.
Nicholas A Eisele, Hanni Lee-Lewis, +2 authors, Cynthia Besch-Williford, Charles R Brown, Deborah M Anderson. less
Am J Pathol, 2011 Mar 02; 178(3). PMID: 21356370 Free PMC article.
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Target-specific mechanics of phagocytosis: protrusive neutrophil response to zymosan differs from the uptake of antibody-tagged pathogens.
Cheng-Yuk Lee, Marc Herant, Volkmar Heinrich.
J Cell Sci, 2011 Mar 10; 124(Pt 7). PMID: 21385838 Free PMC article.
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Characterization of monoclonal antibodies to terminal and internal O-antigen epitopes of Francisella tularensis lipopolysaccharide.
Marly I Roche, Zhaohua Lu, Julia H Hui, Jacqueline Sharon.
Hybridoma (Larchmt), 2011 Apr 07; 30(1). PMID: 21466282 Free PMC article.
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Glycoengineered Pichia produced anti-HER2 is comparable to trastuzumab in preclinical study.
Ningyan Zhang, Liming Liu, +16 authors, Calin Dan Dumitru, Nga Rewa Houston Cummings, Michael Cukan, Youwei Jiang, Yuan Li, Fang Li, Teresa Mitchell, Muralidhar R Mallem, Yangsi Ou, Rohan N Patel, Kim Vo, Hui Wang, Irina Burnina, Byung-Kwon Choi, Hans E Huber, Terrance A Stadheim, Dongxing Zha. less
MAbs, 2011 Apr 14; 3(3). PMID: 21487242 Free PMC article.
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B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies.
Daniel A Winer, Shawn Winer, +16 authors, Lei Shen, Persis P Wadia, Jason Yantha, Geoffrey Paltser, Hubert Tsui, Ping Wu, Matthew G Davidson, Michael N Alonso, Hwei X Leong, Alec Glassford, Maria Caimol, Justin A Kenkel, Thomas F Tedder, Tracey McLaughlin, David B Miklos, H-Michael Dosch, Edgar G Engleman. less
Nat Med, 2011 Apr 19; 17(5). PMID: 21499269 Free PMC article.
Highly Cited.
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Neuronal Fc-gamma receptor I mediated excitatory effects of IgG immune complex on rat dorsal root ganglion neurons.
Lintao Qu, Pu Zhang, Robert H LaMotte, Chao Ma.
Brain Behav Immun, 2011 Apr 28; 25(7). PMID: 21521651 Free PMC article.
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Bi-specific aptamers mediating tumor cell lysis.
Achim Boltz, Birgit Piater, +3 authors, Lars Toleikis, Ralf Guenther, Harald Kolmar, Bjoern Hock. less
J Biol Chem, 2011 May 03; 286(24). PMID: 21531729 Free PMC article.
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Aim2 deficiency in mice suppresses the expression of the inhibitory Fcgamma receptor (FcgammaRIIB) through the induction of the IFN-inducible p202, a lupus susceptibility protein.
Ravichandran Panchanathan, Hui Shen, +4 authors, Xin Duan, Vijay A K Rathinam, Loren D Erickson, Katherine A Fitzgerald, Divaker Choubey. less
J Immunol, 2011 May 10; 186(12). PMID: 21551362 Free PMC article.
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Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals.
Anne-Sophie Dugast, Andrew Tonelli, +8 authors, Christoph T Berger, Margaret E Ackerman, Gaia Sciaranghella, Qingquan Liu, Magdalena Sips, Ildiko Toth, Alicja Piechocka-Trocha, Musie Ghebremichael, Galit Alter. less
Virology, 2011 May 14; 415(2). PMID: 21565376 Free PMC article.
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Recombinant HPV16 E7 assembled into particles induces an immune response and specific tumour protection administered without adjuvant in an animal model.
Linda Petrone, Maria G Ammendolia, +4 authors, Armando Cesolini, Stefano Caimi, Fabiana Superti, Colomba Giorgi, Paola Di Bonito. less
J Transl Med, 2011 May 20; 9. PMID: 21592382 Free PMC article.
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PLD1 rather than PLD2 regulates phorbol-ester-, adhesion-dependent and Fc{gamma}-receptor-stimulated ROS production in neutrophils.
Laura J Norton, Qifeng Zhang, +7 authors, Khalid M Saqib, Heinrich Schrewe, Karol Macura, Karen E Anderson, Craig W Lindsley, H Alex Brown, Simon A Rudge, Michael J O Wakelam. less
J Cell Sci, 2011 May 26; 124(Pt 12). PMID: 21610093 Free PMC article.
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High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations.
Maja Pucić, Ana Knezević, +16 authors, Jana Vidic, Barbara Adamczyk, Mislav Novokmet, Ozren Polasek, Olga Gornik, Sandra Supraha-Goreta, Mark R Wormald, Irma Redzić, Harry Campbell, Alan Wright, Nicholas D Hastie, James F Wilson, Igor Rudan, Manfred Wuhrer, Pauline M Rudd, Djuro Josić, Gordan Lauc. less
Mol Cell Proteomics, 2011 Jun 10; 10(10). PMID: 21653738 Free PMC article.
Highly Cited.
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Passively administered pooled human immunoglobulins exert IL-10 dependent anti-inflammatory effects that protect against fatal HSV encephalitis.
Chandran Ramakrishna, Alain N S Newo, Yueh-Wei Shen, Edouard Cantin.
PLoS Pathog, 2011 Jun 10; 7(6). PMID: 21655109 Free PMC article.
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Clinical cancer therapy by NK cells via antibody-dependent cell-mediated cytotoxicity.
Kory L Alderson, Paul M Sondel.
J Biomed Biotechnol, 2011 Jun 11; 2011. PMID: 21660134 Free PMC article.
Review.
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LyGDI, a novel SHIP-interacting protein, is a negative regulator of FcγR-mediated phagocytosis.
Payal Mehta, Anne-Sophie Wavreille, +8 authors, Steven E Justiniano, Rachel L Marsh, Jianhua Yu, Richard W Burry, David Jarjoura, Timothy Eubank, Michael A Caligiuri, Jonathan P Butchar, Susheela Tridandapani. less
PLoS One, 2011 Jun 23; 6(6). PMID: 21695085 Free PMC article.
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The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells.
Betty Y Chang, Min Mei Huang, +5 authors, Michelle Francesco, Jun Chen, Jeremy Sokolove, Padmaja Magadala, William H Robinson, Joseph J Buggy. less
Arthritis Res Ther, 2011 Jul 15; 13(4). PMID: 21752263 Free PMC article.
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Unique carbohydrate-carbohydrate interactions are required for high affinity binding between FcgammaRIII and antibodies lacking core fucose.
Claudia Ferrara, Sandra Grau, +9 authors, Christiane Jäger, Peter Sondermann, Peter Brünker, Inja Waldhauer, Michael Hennig, Armin Ruf, Arne Christian Rufer, Martine Stihle, Pablo Umaña, Jörg Benz. less
Proc Natl Acad Sci U S A, 2011 Jul 20; 108(31). PMID: 21768335 Free PMC article.
Highly Cited.
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Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells.
Diego G Silva, Stephen R Daley, +6 authors, Jennifer Hogan, Sau K Lee, Charis E Teh, Daniel Y Hu, Kong-Peng Lam, Christopher C Goodnow, Carola G Vinuesa. less
Diabetes, 2011 Jul 27; 60(8). PMID: 21788582 Free PMC article.
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β2-microglobulin is required for the full expression of xenobiotic-induced systemic autoimmunity.
Kenneth M Pollard, Per Hultman, +3 authors, Christopher B Toomey, David M Cauvi, Dwight H Kono, Dwight H Konoc. less
J Immunotoxicol, 2011 Jul 29; 8(3). PMID: 21793797 Free PMC article.
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HER2-based recombinant immunogen to target DCs through FcγRs for cancer immunotherapy.
Ilaria Grazia Zizzari, Filippo Veglia, +12 authors, Federica Taurino, Hassan Rahimi, Elena Quaglino, Francesca Belleudi, Federica Riccardo, Morena Antonilli, Chiara Napoletano, Filippo Bellati, Pierluigi Benedetti-Panici, Maria Rosaria Torrisi, Luigi Frati, Marianna Nuti, Aurelia Rughetti. less
J Mol Med (Berl), 2011 Aug 17; 89(12). PMID: 21845448 Free PMC article.
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A panel of IgG1 b12 variants with selectively diminished or enhanced affinity for Fcγ receptors to define the role of effector functions in protection against HIV.
Brian Moldt, Niccole Schultz, +6 authors, D Cameron Dunlop, Michael D Alpert, Jackson D Harvey, David T Evans, Pascal Poignard, Ann J Hessell, Dennis R Burton. less
J Virol, 2011 Aug 19; 85(20). PMID: 21849450 Free PMC article.
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Inhibitory Fcγ receptor engagement drives adjuvant and anti-tumor activities of agonistic CD40 antibodies.
Fubin Li, Jeffrey V Ravetch.
Science, 2011 Aug 20; 333(6045). PMID: 21852502 Free PMC article.
Highly Cited.
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An essential role for Stat3 in regulating IgG immune complex-induced pulmonary inflammation.
Huifang Tang, Chunguang Yan, +4 authors, Jay Cao, J Vidya Sarma, Eric B Haura, Min Wu, Hongwei Gao. less
FASEB J, 2011 Aug 24; 25(12). PMID: 21859893 Free PMC article.
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The in vivo mechanism of action of CD20 monoclonal antibodies depends on local tumor burden.
Peter Boross, J H Marco Jansen, +8 authors, Simone de Haij, Frank J Beurskens, Cees E van der Poel, Lisette Bevaart, Maaike Nederend, Josée Golay, Jan G J van de Winkel, Paul W H I Parren, Jeanette H W Leusen. less
Haematologica, 2011 Sep 02; 96(12). PMID: 21880632 Free PMC article.
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T cell activation by terminal complex of complement and immune complexes.
Anil K Chauhan, Terry L Moore.
J Biol Chem, 2011 Sep 09; 286(44). PMID: 21900254 Free PMC article.
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Emerging roles for the interferon-inducible p200-family proteins in sex bias in systemic lupus erythematosus.
Divaker Choubey, Ravichandran Panchanathan, +2 authors, Xin Duan, Hongqi Liu, Hongzhu Liu. less
J Interferon Cytokine Res, 2011 Sep 10; 31(12). PMID: 21902548 Free PMC article.
Review.
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TOSO, the Fcmicro receptor, is highly expressed on chronic lymphocytic leukemia B cells, internalizes upon IgM binding, shuttles to the lysosome, and is downregulated in response to TLR activation.
Bérengère Vire, Alexandre David, Adrian Wiestner.
J Immunol, 2011 Sep 13; 187(8). PMID: 21908732 Free PMC article.
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Blurred line between chemotactic chase and phagocytic consumption: an immunophysical single-cell perspective.
Volkmar Heinrich, Cheng-Yuk Lee.
J Cell Sci, 2011 Sep 15; 124(Pt 18). PMID: 21914817 Free PMC article.
Review.
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Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells.
Andrew J Gross, Irina Proekt, Anthony L DeFranco.
Eur J Immunol, 2011 Sep 20; 41(12). PMID: 21928281 Free PMC article.
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Coupling of Fcγ receptor I to Fcγ receptor IIb by SRC kinase mediates C-reactive protein impairment of endothelial function.
Nathan C Sundgren, Weifei Zhu, +6 authors, Ivan S Yuhanna, Ken L Chambliss, Mohamed Ahmed, Keiji Tanigaki, Michihisa Umetani, Chieko Mineo, Philip W Shaul. less
Circ Res, 2011 Sep 24; 109(10). PMID: 21940940 Free PMC article.
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TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells.
Hiroaki Ito, Jessica A Hamerman.
Eur J Immunol, 2011 Oct 01; 42(1). PMID: 21956652 Free PMC article.
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Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC-STAMP).
Ya-Hui Chiu, Kofi A Mensah, +8 authors, Edward M Schwarz, Yawen Ju, Masahiko Takahata, Changyong Feng, Loralee A McMahon, David G Hicks, Ben Panepento, Peter C Keng, Christopher T Ritchlin. less
J Bone Miner Res, 2011 Oct 12; 27(1). PMID: 21987375 Free PMC article.
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Antibody-Mediated Fcγ Receptor-Based Mechanisms of HIV Inhibition: Recent Findings and New Vaccination Strategies.
Vincent Holl, Maryse Peressin, Christiane Moog.
Viruses, 2009 Dec 01; 1(3). PMID: 21994593 Free PMC article.
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Chemoenzymatic synthesis and Fcγ receptor binding of homogeneous glycoforms of antibody Fc domain. Presence of a bisecting sugar moiety enhances the affinity of Fc to FcγIIIa receptor.
Guozhang Zou, Hirofumi Ochiai, +3 authors, Wei Huang, Qiang Yang, Cishan Li, Lai-Xi Wang. less
J Am Chem Soc, 2011 Oct 19; 133(46). PMID: 22004528 Free PMC article.
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Multiple mechanisms of immune suppression by B lymphocytes.
Matthew W Klinker, Steven K Lundy.
Mol Med, 2011 Oct 29; 18. PMID: 22033729 Free PMC article.
Review.
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Activation of cord blood myeloid dendritic cells by Trypanosoma cruzi and parasite-specific antibodies, proliferation of CD8+ T cells, and production of IFN-γ.
Patricia Rodriguez, Yves Carlier, Carine Truyens.
Med Microbiol Immunol, 2011 Nov 01; 201(2). PMID: 22037700
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Chronic alloantibody mediated rejection.
R Neal Smith, Robert B Colvin.
Semin Immunol, 2011 Nov 05; 24(2). PMID: 22051115 Free PMC article.
Review.
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Differential inhibition of trastuzumab- and cetuximab-induced cytotoxicity of cancer cells by immunoglobulin G1 expressing different GM allotypes.
A M Namboodiri, J P Pandey.
Clin Exp Immunol, 2011 Nov 09; 166(3). PMID: 22059994 Free PMC article.
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Fcγ receptor IIB (FcγRIIB) maintains humoral tolerance in the human immune system in vivo.
Anne Baerenwaldt, Anja Lux, +5 authors, Heike Danzer, Bernd M Spriewald, Evelyn Ullrich, Gordon Heidkamp, Diana Dudziak, Falk Nimmerjahn. less
Proc Natl Acad Sci U S A, 2011 Nov 09; 108(46). PMID: 22065769 Free PMC article.
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CD83-stimulated monocytes suppress T-cell immune responses through production of prostaglandin E2.
Liwen Chen, Yibei Zhu, +3 authors, Guangbo Zhang, Chao Gao, Weixue Zhong, Xueguang Zhang. less
Proc Natl Acad Sci U S A, 2011 Nov 09; 108(46). PMID: 22065790 Free PMC article.
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Cell-associated flagella enhance the protection conferred by mucosally-administered attenuated Salmonella Paratyphi A vaccines.
Orit Gat, James E Galen, +5 authors, Sharon Tennant, Raphael Simon, William C Blackwelder, David J Silverman, Marcela F Pasetti, Myron M Levine. less
PLoS Negl Trop Dis, 2011 Nov 10; 5(11). PMID: 22069504 Free PMC article.
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Distinct regulation of murine lupus susceptibility genes by the IRF5/Blimp-1 axis.
Ravichandran Panchanathan, Hongzhu Liu, +4 authors, Hongqi Liu, Chee-Mun Fang, Loren D Erickson, Paula M Pitha, Divaker Choubey. less
J Immunol, 2011 Nov 26; 188(1). PMID: 22116829 Free PMC article.
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The in vitro resistance of IgG2 to proteolytic attack concurs with a comparative paucity of autoantibodies against peptide analogs of the IgG2 hinge.
Randall J Brezski, Allison Oberholtzer, Brandy Strake, Robert E Jordan.
MAbs, 2011 Nov 30; 3(6). PMID: 22123056 Free PMC article.
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The impact of glycosylation on monoclonal antibody conformation and stability.
Kai Zheng, Christopher Bantog, Robert Bayer.
MAbs, 2011 Nov 30; 3(6). PMID: 22123061 Free PMC article.
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Anti-tumor activity and toxicokinetics analysis of MGAH22, an anti-HER2 monoclonal antibody with enhanced Fcγ receptor binding properties.
Jeffrey L Nordstrom, Sergey Gorlatov, +12 authors, Wenjun Zhang, Yinhua Yang, Ling Huang, Steve Burke, Hua Li, Valentina Ciccarone, Tengfei Zhang, Jeffrey Stavenhagen, Scott Koenig, Stanford J Stewart, Paul A Moore, Syd Johnson, Ezio Bonvini. less
Breast Cancer Res, 2011 Dec 02; 13(6). PMID: 22129105 Free PMC article.
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Emerging technologies for making glycan-defined glycoproteins.
Lai-Xi Wang, Joseph V Lomino.
ACS Chem Biol, 2011 Dec 07; 7(1). PMID: 22141574 Free PMC article.
Review.
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C5a-regulated CCAAT/enhancer-binding proteins β and δ are essential in Fcγ receptor-mediated inflammatory cytokine and chemokine production in macrophages.
Chunguang Yan, Mei Zhu, +2 authors, Jennifer Staiger, Peter F Johnson, Hongwei Gao. less
J Biol Chem, 2011 Dec 08; 287(5). PMID: 22147692 Free PMC article.
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Age related changes in microglial phenotype vary between CNS regions: grey versus white matter differences.
Adam D Hart, Andreas Wyttenbach, V Hugh Perry, Jessica L Teeling.
Brain Behav Immun, 2011 Dec 14; 26(5). PMID: 22155499 Free PMC article.
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Immune mediated diseases and immune modulation in the neurocritical care unit.
Gloria von Geldern, Thomas McPharlin, Kyra Becker.
Neurotherapeutics, 2011 Dec 14; 9(1). PMID: 22161307 Free PMC article.
Review.
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Role of novel rat-specific Fc receptor in macrophage activation associated with crescentic glomerulonephritis.
Theresa H Page, Zelpha D'Souza, +5 authors, Satoshi Nakanishi, Tadao Serikawa, Charles D Pusey, Timothy J Aitman, H Terence Cook, Jacques Behmoaras. less
J Biol Chem, 2011 Dec 21; 287(8). PMID: 22184119 Free PMC article.
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FcγRIIIa expression on monocytes in rheumatoid arthritis: role in immune-complex stimulated TNF production and non-response to methotrexate therapy.
Dawn L Cooper, Stephen G Martin, +7 authors, James I Robinson, Sarah L Mackie, Christopher J Charles, Jackie Nam, YEAR Consortium, John D Isaacs, Paul Emery, Ann W Morgan. less
PLoS One, 2012 Jan 12; 7(1). PMID: 22235253 Free PMC article.
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Immune complexes and late complement proteins trigger activation of Syk tyrosine kinase in human CD4(+) T cells.
A K Chauhan, T L Moore.
Clin Exp Immunol, 2012 Jan 13; 167(2). PMID: 22235999 Free PMC article.
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Antibody inhibition of a viral type 1 interferon decoy receptor cures a viral disease by restoring interferon signaling in the liver.
Ren-Huan Xu, Daniel Rubio, +7 authors, Felicia Roscoe, Tracy E Krouse, Mary Ellen Truckenmiller, Christopher C Norbury, Paul N Hudson, Inger K Damon, Antonio Alcamí, Luis J Sigal. less
PLoS Pathog, 2012 Jan 14; 8(1). PMID: 22241999 Free PMC article.
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A serotype 3 pneumococcal capsular polysaccharide-specific monoclonal antibody requires Fcγ receptor III and macrophages to mediate protection against pneumococcal pneumonia in mice.
Sarah Weber, Haijun Tian, Nico van Rooijen, Liise-Anne Pirofski.
Infect Immun, 2012 Feb 01; 80(4). PMID: 22290146 Free PMC article.
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The influence of ACPA status and characteristics on the course of RA.
Annemiek Willemze, Leendert A Trouw, René E M Toes, Tom W J Huizinga.
Nat Rev Rheumatol, 2012 Feb 02; 8(3). PMID: 22293763
Review.
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Feasibility of cross-protective vaccination against flaviviruses of the Japanese encephalitis serocomplex.
Mario Lobigs, Michael S Diamond.
Expert Rev Vaccines, 2012 Feb 09; 11(2). PMID: 22309667 Free PMC article.
Review.
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Analytical characterization of ch14.18: a mouse-human chimeric disialoganglioside-specific therapeutic antibody.
Gopalan Soman, Abraham T Kallarakal, +6 authors, Dennis Michiel, Xiaoyi Yang, Nirmala Saptharish, Hengguang Jiang, Steve Giardina, John Gilly, George Mitra. less
MAbs, 2012 Feb 14; 4(1). PMID: 22327432 Free PMC article.
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Polymeric human Fc-fusion proteins with modified effector functions.
David N A Mekhaiel, Daniel M Czajkowsky, +9 authors, Jan Terje Andersen, Jianguo Shi, Marwa El-Faham, Michael Doenhoff, Richard S McIntosh, Inger Sandlie, Jianfeng He, Jun Hu, Zhifeng Shao, Richard J Pleass. less
Sci Rep, 2012 Feb 23; 1. PMID: 22355641 Free PMC article.
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ITAM-coupled receptors inhibit IFNAR signaling and alter macrophage responses to TLR4 and Listeria monocytogenes.
Linda Huynh, Lu Wang, +2 authors, Chao Shi, Kyung-Hyun Park-Min, Lionel B Ivashkiv. less
J Immunol, 2012 Mar 01; 188(7). PMID: 22368279 Free PMC article.
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Intravenous immunoglobulins modulate neutrophil activation and vascular injury through FcγRIII and SHP-1.
Jung-Eun Jang, Andrés Hidalgo, Paul S Frenette.
Circ Res, 2012 Mar 15; 110(8). PMID: 22415018 Free PMC article.
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The role of sialic acid as a modulator of the anti-inflammatory activity of IgG.
Sybille Böhm, Inessa Schwab, Anja Lux, Falk Nimmerjahn.
Semin Immunopathol, 2012 Mar 23; 34(3). PMID: 22437760
Review.
|
Lyn but not Fyn kinase controls IgG-mediated systemic anaphylaxis.
Yves T Falanga, Natalia S Chaimowitz, +14 authors, Nicolas Charles, Fred D Finkelman, Nicholas A Pullen, Suzanne Barbour, Kevin Dholaria, Travis Faber, Motunrayo Kolawole, Bernice Huang, Sandra Odom, Juan Rivera, Jason Carlyon, Daniel H Conrad, Sarah Spiegel, Carole A Oskeritzian, John J Ryan. less
J Immunol, 2012 Mar 28; 188(9). PMID: 22450804 Free PMC article.
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Fc receptor-targeted therapies for the treatment of inflammation, cancer and beyond.
P Mark Hogarth, Geoffrey A Pietersz.
Nat Rev Drug Discov, 2012 Mar 31; 11(4). PMID: 22460124
Highly Cited. Review.
|
Prevalence of collagen VII-specific autoantibodies in patients with autoimmune and inflammatory diseases.
Emilia Licarete, Susanne Ganz, +9 authors, Martin J Recknagel, Giovanni Di Zenzo, Takashi Hashimoto, Michael Hertl, Giovanna Zambruno, Gheorghe Hundorfean, Jonas Mudter, Markus F Neurath, Leena Bruckner-Tuderman, Cassian Sitaru. less
BMC Immunol, 2012 Apr 05; 13. PMID: 22471736 Free PMC article.
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Mouse model recapitulating human Fcγ receptor structural and functional diversity.
Patrick Smith, David J DiLillo, +2 authors, Stylianos Bournazos, Fubin Li, Jeffrey V Ravetch. less
Proc Natl Acad Sci U S A, 2012 Apr 05; 109(16). PMID: 22474370 Free PMC article.
Highly Cited.
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The biological significance of evolution in autoimmune phenomena.
Carlos A Cañas, Felipe Cañas.
Autoimmune Dis, 2012 Apr 07; 2012. PMID: 22482039 Free PMC article.
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Selective deactivation of serum IgG: a general strategy for the enhancement of monoclonal antibody receptor interactions.
Kavitha Baruah, Thomas A Bowden, +3 authors, Benjamin A Krishna, Raymond A Dwek, Max Crispin, Christopher N Scanlan. less
J Mol Biol, 2012 Apr 10; 420(1-2). PMID: 22484364 Free PMC article.
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Cutting edge: human FcRL4 and FcRL5 are receptors for IgA and IgG.
Timothy J Wilson, Anja Fuchs, Marco Colonna.
J Immunol, 2012 Apr 12; 188(10). PMID: 22491254 Free PMC article.
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FcγRI mediates serum amyloid P inhibition of fibrocyte differentiation.
Jeffrey R Crawford, Darrell Pilling, Richard H Gomer.
J Leukoc Biol, 2012 Apr 12; 92(4). PMID: 22493081 Free PMC article.
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Cancer and innate immune system interactions: translational potentials for cancer immunotherapy.
Yanan Liu, Gang Zeng.
J Immunother, 2012 Apr 13; 35(4). PMID: 22495387 Free PMC article.
Review.
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Lepidopteran cells, an alternative for the production of recombinant antibodies?
Martine Cérutti, Josée Golay.
MAbs, 2012 Apr 26; 4(3). PMID: 22531440 Free PMC article.
Review.
|
Quantitative evaluation of fucose reducing effects in a humanized antibody on Fcγ receptor binding and antibody-dependent cell-mediated cytotoxicity activities.
Shan Chung, Valerie Quarmby, +9 authors, Xiaoying Gao, Yong Ying, Linda Lin, Chae Reed, Chris Fong, Wendy Lau, Zhihua J Qiu, Amy Shen, Martin Vanderlaan, An Song. less
MAbs, 2012 Apr 26; 4(3). PMID: 22531441 Free PMC article.
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Development and validation of an antibody-dependent cell-mediated cytotoxicity-reporter gene assay.
Bhavin S Parekh, Elaine Berger, +6 authors, Sharon Sibley, Suntara Cahya, Liqun Xiao, Melinda Ann LaCerte, Peter Vaillancourt, Scott Wooden, Dennis Gately. less
MAbs, 2012 Apr 26; 4(3). PMID: 22531445 Free PMC article.
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Immunopotentiating properties of a multispecific α-anti-idiotype antibody.
Tays Hernández, Cristina Mateo de Acosta, Rolando Pérez.
MAbs, 2012 Apr 26; 4(3). PMID: 22531446 Free PMC article.
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Exacerbation of collagen induced arthritis by Fcγ receptor targeted collagen peptide due to enhanced inflammatory chemokine and cytokine production.
Eszter Szarka, Zsuzsa Neer, +6 authors, Péter Balogh, Monika Adori, Adrienn Angyal, József Prechl, Endre Kiss, Dorottya Kövesdi, Gabriella Sármay. less
Biologics, 2012 Apr 26; 6. PMID: 22532778 Free PMC article.
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Antibodies targeting dengue virus envelope domain III are not required for serotype-specific protection or prevention of enhancement in vivo.
Katherine L Williams, Wahala M P B Wahala, +2 authors, Susana Orozco, Aravinda M de Silva, Eva Harris. less
Virology, 2012 Apr 28; 429(1). PMID: 22537810 Free PMC article.
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Prevention and treatment of allergic inflammation by an Fcγ-Der f2 fusion protein in a murine model of dust mite-induced asthma.
Li-hui Lin, Ping Zheng, +6 authors, John W M Yuen, Juan Wang, Juan Zhou, Cun-quan Kong, Xia Peng, Jia Li, Li Li. less
Immunol Res, 2012 Apr 28; 52(3). PMID: 22539132
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Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life.
Jan Terje Andersen, Stian Foss, +5 authors, Vania E Kenanova, Tove Olafsen, Ingvild S Leikfoss, Derry C Roopenian, Anna M Wu, Inger Sandlie. less
J Biol Chem, 2012 May 10; 287(27). PMID: 22570488 Free PMC article.
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Ultrasensitive capillary electrophoretic analysis of potentially immunogenic carbohydrate residues in biologics: galactose-α-1,3-galactose containing oligosaccharides.
Zoltan Szabo, Andras Guttman, +3 authors, Jonathan Bones, Randi L Shand, David Meh, Barry L Karger. less
Mol Pharm, 2012 May 11; 9(6). PMID: 22571495 Free PMC article.
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NMR characterization of immunoglobulin G Fc glycan motion on enzymatic sialylation.
Adam W Barb, Lu Meng, +3 authors, Zhongwei Gao, Roy W Johnson, Kelley W Moremen, James H Prestegard. less
Biochemistry, 2012 May 12; 51(22). PMID: 22574931 Free PMC article.
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The Fyn-STAT5 Pathway: A New Frontier in IgE- and IgG-Mediated Mast Cell Signaling.
Nicholas A Pullen, Yves T Falanga, Johanna K Morales, John J Ryan.
Front Immunol, 2012 May 18; 3. PMID: 22593761 Free PMC article.
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Evolutionary history of copy-number-variable locus for the low-affinity Fcγ receptor: mutation rate, autoimmune disease, and the legacy of helminth infection.
Lee R Machado, Robert J Hardwick, +4 authors, Jennifer Bowdrey, Helen Bogle, Timothy J Knowles, Manuela Sironi, Edward J Hollox. less
Am J Hum Genet, 2012 May 23; 90(6). PMID: 22608500 Free PMC article.
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Antiphagocytic function of an IgG glycosyl hydrolase from Streptococcus equi subsp. equi and its use as a vaccine component.
Margareta Flock, Lars Frykberg, +2 authors, Markus Sköld, Bengt Guss, Jan-Ingmar Flock. less
Infect Immun, 2012 May 23; 80(8). PMID: 22615244 Free PMC article.
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Increasing the clinical efficacy of NK and antibody-mediated cancer immunotherapy: potential predictors of successful clinical outcome based on observations in high-risk neuroblastoma.
Tony A Koehn, Lori L Trimble, +5 authors, Kory L Alderson, Amy K Erbe, Kimberly A McDowell, Bartosz Grzywacz, Jacquelyn A Hank, Paul M Sondel. less
Front Pharmacol, 2012 May 25; 3. PMID: 22623917 Free PMC article.
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High-content live-cell imaging assay used to establish mechanism of trastuzumab emtansine (T-DM1)--mediated inhibition of platelet production.
Jonathan N Thon, Matthew T Devine, +2 authors, Antonija Jurak Begonja, Jay Tibbitts, Joseph E Italiano. less
Blood, 2012 Jun 06; 120(10). PMID: 22665936 Free PMC article.
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Glycans in sera of amyotrophic lateral sclerosis patients and their role in killing neuronal cells.
Meital Edri-Brami, Benyamin Rosental, +7 authors, Dana Hayoun, Michael Welt, Hila Rosen, Itzhak Wirguin, Beatrice Nefussy, Vivian E Drory, Angel Porgador, Rachel G Lichtenstein. less
PLoS One, 2012 Jun 06; 7(5). PMID: 22666317 Free PMC article.
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Antibody-dependent cellular cytotoxicity against primary HIV-infected CD4+ T cells is directly associated with the magnitude of surface IgG binding.
Adjoa Smalls-Mantey, Nicole Doria-Rose, +13 authors, Rachel Klein, Andy Patamawenu, Stephen A Migueles, Sung-Youl Ko, Claire W Hallahan, Hing Wong, Bai Liu, Lijing You, Johannes Scheid, John C Kappes, Christina Ochsenbauer, Gary J Nabel, John R Mascola, Mark Connors. less
J Virol, 2012 Jun 08; 86(16). PMID: 22674985 Free PMC article.
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Production, characterization, and pharmacokinetic properties of antibodies with N-linked mannose-5 glycans.
Marcella Yu, Darren Brown, +6 authors, Chae Reed, Shan Chung, Jeff Lutman, Eric Stefanich, Anne Wong, Jean-Philippe Stephan, Robert Bayer. less
MAbs, 2012 Jun 16; 4(4). PMID: 22699308 Free PMC article.
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Fc-Gamma Receptor 3B Copy Number Variation Is Not a Risk Factor for Behçet's Disease.
Rachel Black, Sue Lester, +8 authors, Emma Dunstan, Farhad Shahram, Abdolhadi Nadji, Noushin Bayat, Kayvan Saeedfar, Naghmeh Ziaei, Catherine Hill, Maureen Rischmueller, Fereydoun Davatchi. less
Int J Rheumatol, 2012 Jun 16; 2012. PMID: 22701122 Free PMC article.
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Apoptotic and antitumor activity of death receptor antibodies require inhibitory Fcγ receptor engagement.
Fubin Li, Jeffrey V Ravetch.
Proc Natl Acad Sci U S A, 2012 Jun 23; 109(27). PMID: 22723355 Free PMC article.
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The interactions of human neutrophils with shiga toxins and related plant toxins: danger or safety?
Maurizio Brigotti.
Toxins (Basel), 2012 Jun 29; 4(3). PMID: 22741061 Free PMC article.
Review.
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Chemoenzymatic glycoengineering of intact IgG antibodies for gain of functions.
Wei Huang, John Giddens, +2 authors, Shu-Quan Fan, Christian Toonstra, Lai-Xi Wang. less
J Am Chem Soc, 2012 Jul 04; 134(29). PMID: 22747414 Free PMC article.
Highly Cited.
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Revisiting the role of glycosylation in the structure of human IgG Fc.
M Jack Borrok, Sang Taek Jung, +2 authors, Tae Hyun Kang, Arthur F Monzingo, George Georgiou. less
ACS Chem Biol, 2012 Jul 04; 7(9). PMID: 22747430 Free PMC article.
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Antibody-recruiting molecules: an emerging paradigm for engaging immune function in treating human disease.
Patrick J McEnaney, Christopher G Parker, Andrew X Zhang, David A Spiegel.
ACS Chem Biol, 2012 Jul 05; 7(7). PMID: 22758917 Free PMC article.
Systematic Review.
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Association of FCRL4 polymorphisms on disease susceptibility and severity of ankylosing spondylitis in Chinese Han population.
Zhen Zeng, Zhenhua Duan, +11 authors, Tianchen Zhang, Sheng Wang, Guixing Li, Yang Mei, Jing Gao, Rui Ge, Dongqing Ye, Yanfeng Zou, Shengqian Xu, Jianhua Xu, Li Zhang, Faming Pan. less
Clin Rheumatol, 2012 Jul 11; 31(10). PMID: 22777505
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Transient receptor potential canonical 3 (TRPC3) is required for IgG immune complex-induced excitation of the rat dorsal root ganglion neurons.
Lintao Qu, Yumei Li, +3 authors, Xinghua Pan, Pu Zhang, Robert H LaMotte, Chao Ma. less
J Neurosci, 2012 Jul 13; 32(28). PMID: 22787041 Free PMC article.
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Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study.
David H Cribbs, Nicole C Berchtold, +4 authors, Victoria Perreau, Paul D Coleman, Joseph Rogers, Andrea J Tenner, Carl W Cotman. less
J Neuroinflammation, 2012 Jul 25; 9. PMID: 22824372 Free PMC article.
Highly Cited.
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Fc-fusion proteins: new developments and future perspectives.
Daniel M Czajkowsky, Jun Hu, Zhifeng Shao, Richard J Pleass.
EMBO Mol Med, 2012 Jul 28; 4(10). PMID: 22837174 Free PMC article.
Highly Cited. Review.
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Interferon-inducible Ifi200-family genes as modifiers of lupus susceptibility.
Divaker Choubey.
Immunol Lett, 2012 Jul 31; 147(1-2). PMID: 22841963 Free PMC article.
Review.
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Cross-presentation of IgG-containing immune complexes.
Kristi Baker, Timo Rath, +2 authors, Wayne I Lencer, Edda Fiebiger, Richard S Blumberg. less
Cell Mol Life Sci, 2012 Aug 01; 70(8). PMID: 22847331 Free PMC article.
Review.
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Association of Fcγ receptor IIB polymorphism with cryptococcal meningitis in HIV-uninfected Chinese patients.
Xiu-Ping Hu, Ji-Qin Wu, +5 authors, Li-Ping Zhu, Xuan Wang, Bin Xu, Rui-Ying Wang, Xue-Ting Ou, Xin-Hua Weng. less
PLoS One, 2012 Aug 11; 7(8). PMID: 22879986 Free PMC article.
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Genetic polymorphisms of FCGR2A encoding Fcγ receptor IIa in a Japanese population and functional analysis of the L273P variant.
Minoru Tada, Akiko Ishii-Watabe, +23 authors, Keiko Maekawa, Hiromi Fukushima-Uesaka, Kouichi Kurose, Takuo Suzuki, Nahoko Kaniwa, Jun-Ichi Sawada, Nana Kawasaki, Takako Eguchi Nakajima, Ken Kato, Yasuhide Yamada, Yasuhiro Shimada, Teruhiko Yoshida, Takashi Ura, Miyuki Saito, Kei Muro, Toshihiko Doi, Nozomu Fuse, Takayuki Yoshino, Atsushi Ohtsu, Nagahiro Saijo, Haruhiro Okuda, Tetsuya Hamaguchi, Yoshiro Saito, Yasuhiro Matsumura. less
Immunogenetics, 2012 Aug 21; 64(12). PMID: 22903236
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A general requirement for FcγRIIB co-engagement of agonistic anti-TNFR antibodies.
Fubin Li, Jeffrey V Ravetch.
Cell Cycle, 2012 Aug 25; 11(18). PMID: 22918247 Free PMC article.
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Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1.
Christian M Karsten, Manoj K Pandey, +23 authors, Julia Figge, Regina Kilchenstein, Philip R Taylor, Marcela Rosas, Jacqueline U McDonald, Selinda J Orr, Markus Berger, Dominique Petzold, Veroniqué Blanchard, André Winkler, Constanze Hess, Delyth M Reid, Irina V Majoul, Richard T Strait, Nathaniel L Harris, Gabriele Köhl, Eva Wex, Ralf Ludwig, Detlef Zillikens, Falk Nimmerjahn, Fred D Finkelman, Gordon D Brown, Marc Ehlers, Jörg Köhl. less
Nat Med, 2012 Aug 28; 18(9). PMID: 22922409 Free PMC article.
Highly Cited.
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ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge.
Michael D Alpert, Jackson D Harvey, +9 authors, W Anderson Lauer, R Keith Reeves, Michael Piatak, Angela Carville, Keith G Mansfield, Jeffrey D Lifson, Wenjun Li, Ronald C Desrosiers, R Paul Johnson, David T Evans. less
PLoS Pathog, 2012 Aug 29; 8(8). PMID: 22927823 Free PMC article.
Highly Cited.
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A novel assay for antibody-dependent cell-mediated cytotoxicity against HIV-1- or SIV-infected cells reveals incomplete overlap with antibodies measured by neutralization and binding assays.
Michael D Alpert, Lisa N Heyer, +4 authors, David E J Williams, Jackson D Harvey, Thomas Greenough, Maria Allhorn, David T Evans. less
J Virol, 2012 Aug 31; 86(22). PMID: 22933282 Free PMC article.
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Molecular characterization of novel trispecific ErbB-cMet-IGF1R antibodies and their antigen-binding properties.
R Castoldi, U Jucknischke, +5 authors, L P Pradel, E Arnold, C Klein, S Scheiblich, G Niederfellner, C Sustmann. less
Protein Eng Des Sel, 2012 Sep 01; 25(10). PMID: 22936109 Free PMC article.
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Fc gamma receptor CD64 modulates the inhibitory activity of infliximab.
Kacper A Wojtal, Gerhard Rogler, +7 authors, Michael Scharl, Luc Biedermann, Pascal Frei, Michael Fried, Achim Weber, Jyrki J Eloranta, Gerd A Kullak-Ublick, Stephan R Vavricka. less
PLoS One, 2012 Sep 01; 7(8). PMID: 22937039 Free PMC article.
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A sweet spot to control complement-induced inflammation.
Daniel Ricklin, Edimara S Reis, John D Lambris.
Nat Med, 2012 Sep 11; 18(9). PMID: 22961162
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T cell responses induced by adenoviral vectored vaccines can be adjuvanted by fusion of antigen to the oligomerization domain of C4b-binding protein.
Emily K Forbes, Simone C de Cassan, +8 authors, David Llewellyn, Sumi Biswas, Anna L Goodman, Matthew G Cottingham, Carole A Long, Richard J Pleass, Adrian V S Hill, Fergal Hill, Simon J Draper. less
PLoS One, 2012 Sep 18; 7(9). PMID: 22984589 Free PMC article.
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Critical role of the IgM Fc receptor in IgM homeostasis, B-cell survival, and humoral immune responses.
Rika Ouchida, Hiromi Mori, +5 authors, Koji Hase, Hiroyuki Takatsu, Tomohiro Kurosaki, Takeshi Tokuhisa, Hiroshi Ohno, Ji-Yang Wang. less
Proc Natl Acad Sci U S A, 2012 Sep 19; 109(40). PMID: 22988094 Free PMC article.
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The Plasmodium falciparum erythrocyte invasion ligand Pfrh4 as a target of functional and protective human antibodies against malaria.
Linda Reiling, Jack S Richards, +14 authors, Freya J I Fowkes, Danny W Wilson, Watcharee Chokejindachai, Alyssa E Barry, Wai-Hong Tham, Janine Stubbs, Christine Langer, John Donelson, Pascal Michon, Livingstone Tavul, Brendan S Crabb, Peter M Siba, Alan F Cowman, Ivo Mueller, James G Beeson. less
PLoS One, 2012 Oct 03; 7(9). PMID: 23028883 Free PMC article.
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FCGR2C genotyping by pyrosequencing reveals linkage disequilibrium with FCGR3A V158F and FCGR2A H131R polymorphisms in a Caucasian population.
Julien Lejeune, Benoît Piègu, +3 authors, Valérie Gouilleux-Gruart, Marc Ohresser, Hervé Watier, Gilles Thibault. less
MAbs, 2012 Oct 04; 4(6). PMID: 23032993 Free PMC article.
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Treatment with low doses of polyclonal immunoglobulin improves B cell function during immune reconstitution in a murine model.
Ana Barahona Afonso, Lígia Neves Justo, +7 authors, Ana Cristina Queirós, Constantin Fesel, Maria Salomé Cabral, Maria Gomes da Silva, Luis Porrata, Svetomir Markovic, Ana Elisabete Pires, Cristina João. less
J Clin Immunol, 2012 Oct 12; 33(2). PMID: 23054339
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A New Kid on the Block: IL-10+ Regulatory B Cells and a Possible Role In Psoriasis.
Kamruz Darabi, Rohit Jaiswal, +3 authors, Sarah G Hostetler, Mark A Bechtel, Matthew J Zirwas, Patricia Witman. less
J Pediatr Pharmacol Ther, 2009 Jul 01; 14(3). PMID: 23055903 Free PMC article.
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The chicken SLAM family.
Christian Straub, Birgit C Viertlboeck, Thomas W Göbel.
Immunogenetics, 2012 Oct 16; 65(1). PMID: 23064403
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Immune complexes isolated from patients with pulmonary tuberculosis modulate the activation and function of normal granulocytes.
P Senbagavalli, J Nancy Hilda, +3 authors, V D Ramanathan, V Kumaraswami, Thomas B Nutman, Subash Babu. less
Clin Vaccine Immunol, 2012 Oct 27; 19(12). PMID: 23100480 Free PMC article.
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Analysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity.
Marion Espéli, Menna R Clatworthy, +5 authors, Susanne Bökers, Kate E Lawlor, Antony J Cutler, Frank Köntgen, Paul A Lyons, Kenneth G C Smith. less
J Exp Med, 2012 Oct 31; 209(12). PMID: 23109709 Free PMC article.
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Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and FcγR signaling.
Christian D Sadik, Nancy D Kim, Yoichiro Iwakura, Andrew D Luster.
Proc Natl Acad Sci U S A, 2012 Nov 01; 109(46). PMID: 23112187 Free PMC article.
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Regulation of allograft survival by inhibitory FcγRIIb signaling.
Chris J Callaghan, Thet Su Win, +9 authors, Reza Motallebzadeh, Thomas M Conlon, Manu Chhabra, Inês Harper, Siva Sivaganesh, Eleanor M Bolton, J Andrew Bradley, Rebecca J Brownlie, Kenneth G C Smith, Gavin J Pettigrew. less
J Immunol, 2012 Nov 15; 189(12). PMID: 23150718 Free PMC article.
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The contribution of allergen-specific IgG to the development of th2-mediated airway inflammation.
Jesse W Williams, Melissa Y Tjota, Anne I Sperling.
J Allergy (Cairo), 2012 Nov 15; 2012. PMID: 23150737 Free PMC article.
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Quorum sensing contributes to activated IgM-secreting B cell homeostasis.
Caroline Montaudouin, Marie Anson, +9 authors, Yi Hao, Susanne V Duncker, Tahia Fernandez, Emmanuelle Gaudin, Michael Ehrenstein, William G Kerr, Jean-Hervé Colle, Pierre Bruhns, Marc Daëron, António A Freitas. less
J Immunol, 2012 Dec 05; 190(1). PMID: 23209322 Free PMC article.
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Recombinant human cytomegalovirus (HCMV) RL13 binds human immunoglobulin G Fc.
Mirko Cortese, Stefano Calò, +3 authors, Romina D'Aurizio, Anders Lilja, Nicola Pacchiani, Marcello Merola. less
PLoS One, 2012 Dec 12; 7(11). PMID: 23226246 Free PMC article.
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Mechanisms of action of CD20 antibodies.
Peter Boross, Jeanette H W Leusen.
Am J Cancer Res, 2012 Dec 12; 2(6). PMID: 23226614 Free PMC article.
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ADAM17 cleaves CD16b (FcγRIIIb) in human neutrophils.
Yue Wang, Jianming Wu, +3 authors, Robert Newton, Nooshin S Bahaie, Chunmei Long, Bruce Walcheck. less
Biochim Biophys Acta, 2012 Dec 12; 1833(3). PMID: 23228566 Free PMC article.
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Antibody orientation at bacterial surfaces is related to invasive infection.
Pontus Nordenfelt, Sofia Waldemarson, +4 authors, Adam Linder, Matthias Mörgelin, Christofer Karlsson, Johan Malmström, Lars Björck. less
J Exp Med, 2012 Dec 12; 209(13). PMID: 23230002 Free PMC article.
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Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for α345NC1 hexamers.
Florina Olaru, Xu-Ping Wang, +8 authors, Wentian Luo, Linna Ge, Jeffrey H Miner, Sandra Kleinau, Xochiquetzal J Geiger, Andrew Wasiluk, Laurence Heidet, A Richard Kitching, Dorin-Bogdan Borza. less
J Immunol, 2013 Jan 11; 190(4). PMID: 23303673 Free PMC article.
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Macrophage and NK-mediated killing of precursor-B acute lymphoblastic leukemia cells targeted with a-fucosylated anti-CD19 humanized antibodies.
K Matlawska-Wasowska, E Ward, +4 authors, S Stevens, Y Wang, R Herbst, S S Winter, B S Wilson. less
Leukemia, 2013 Jan 12; 27(6). PMID: 23307031 Free PMC article.
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β(2) integrins inhibit TLR responses by regulating NF-κB pathway and p38 MAPK activation.
Nathan K Yee, Jessica A Hamerman.
Eur J Immunol, 2013 Jan 12; 43(3). PMID: 23310953 Free PMC article.
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Serum amyloid P inhibits granulocyte adhesion.
Anu S Maharjan, David Roife, Derrick Brazill, Richard H Gomer.
Fibrogenesis Tissue Repair, 2013 Jan 18; 6(1). PMID: 23324174 Free PMC article.
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Application of knockout mouse models to investigate the influence of FcγR on the pharmacokinetics and anti-platelet effects of MWReg30, a monoclonal anti-GPIIb antibody.
Lubna Abuqayyas, Xiaoyan Zhang, Joseph P Balthasar.
Int J Pharm, 2013 Feb 02; 444(1-2). PMID: 23370434 Free PMC article.
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Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Gordan Lauc, Jennifer E Huffman, +36 authors, Maja Pučić, Lina Zgaga, Barbara Adamczyk, Ana Mužinić, Mislav Novokmet, Ozren Polašek, Olga Gornik, Jasminka Krištić, Toma Keser, Veronique Vitart, Blanca Scheijen, Hae-Won Uh, Mariam Molokhia, Alan Leslie Patrick, Paul McKeigue, Ivana Kolčić, Ivan Krešimir Lukić, Olivia Swann, Frank N van Leeuwen, L Renee Ruhaak, Jeanine J Houwing-Duistermaat, P Eline Slagboom, Marian Beekman, Anton J M de Craen, André M Deelder, Qiang Zeng, Wei Wang, Nicholas D Hastie, Ulf Gyllensten, James F Wilson, Manfred Wuhrer, Alan F Wright, Pauline M Rudd, Caroline Hayward, Yurii Aulchenko, Harry Campbell, Igor Rudan. less
PLoS Genet, 2013 Feb 06; 9(1). PMID: 23382691 Free PMC article.
Highly Cited.
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In-depth characterization of N-linked oligosaccharides using fluoride-mediated negative ion microfluidic chip LC-MS.
Wenqin Ni, Jonathan Bones, Barry L Karger.
Anal Chem, 2013 Feb 13; 85(6). PMID: 23398125 Free PMC article.
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Antibody-DEPENDENT, FcγRI-mediated neutralization of HIV-1 in TZM-bl cells occurs independently of phagocytosis.
Lautaro G Perez, Susan Zolla-Pazner, David C Montefiori.
J Virol, 2013 Feb 15; 87(9). PMID: 23408628 Free PMC article.
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Intravenous immunoglobulin therapy: how does IgG modulate the immune system?
Inessa Schwab, Falk Nimmerjahn.
Nat Rev Immunol, 2013 Feb 16; 13(3). PMID: 23411799
Highly Cited. Review.
|
Combined analysis of genome-wide-linked susceptibility loci to Kawasaki disease in Han Chinese.
Yuanlong Yan, Yongyi Ma, +8 authors, Yunqiang Liu, Hongde Hu, Ying Shen, Sizhong Zhang, Yongxing Ma, Dachang Tao, Qing Wu, Qian Peng, Yuan Yang. less
Hum Genet, 2013 Mar 05; 132(6). PMID: 23456091
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B cells and their mediators as targets for therapy in solid tumors.
Andrew J Gunderson, Lisa M Coussens.
Exp Cell Res, 2013 Mar 19; 319(11). PMID: 23499742 Free PMC article.
Review.
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Toll-like receptor 2 ligands regulate monocyte Fcγ receptor expression and function.
Prexy Shah, Kavin Fatehchand, +6 authors, Hemal Patel, Huiqing Fang, Steven E Justiniano, Xiaokui Mo, David Jarjoura, Susheela Tridandapani, Jonathan P Butchar. less
J Biol Chem, 2013 Mar 19; 288(17). PMID: 23504312 Free PMC article.
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Controlling natural killer cell responses: integration of signals for activation and inhibition.
Eric O Long, Hun Sik Kim, +2 authors, Dongfang Liu, Mary E Peterson, Sumati Rajagopalan. less
Annu Rev Immunol, 2013 Mar 23; 31. PMID: 23516982 Free PMC article.
Highly Cited. Review.
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Natural killer cell mediated antibody-dependent cellular cytotoxicity in tumor immunotherapy with therapeutic antibodies.
Ursula J E Seidel, Patrick Schlegel, Peter Lang.
Front Immunol, 2013 Apr 02; 4. PMID: 23543707 Free PMC article.
Highly Cited.
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B-cell targeted therapeutics in clinical development.
Stephan Blüml, Kathleen McKeever, +2 authors, Rachel Ettinger, Josef Smolen, Ronald Herbst. less
Arthritis Res Ther, 2013 Apr 10; 15 Suppl 1. PMID: 23566679 Free PMC article.
Review.
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New developments in C5a receptor signaling.
J Vidya Sarma, Peter A Ward.
Cell Health Cytoskelet, 2013 Apr 12; 4. PMID: 23576881 Free PMC article.
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IL-33-dependent induction of allergic lung inflammation by FcγRIII signaling.
Melissa Y Tjota, Jesse W Williams, +7 authors, Tiffany Lu, Bryan S Clay, Tiara Byrd, Cara L Hrusch, Donna C Decker, Claudia Alves de Araujo, Paul J Bryce, Anne I Sperling. less
J Clin Invest, 2013 Apr 16; 123(5). PMID: 23585480 Free PMC article.
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FCGR2B and FCRLB gene polymorphisms associated with IgA nephropathy.
Xu-jie Zhou, Fa-juan Cheng, +5 authors, Yuan-yuan Qi, Yan-feng Zhao, Ping Hou, Li Zhu, Ji-cheng Lv, Hong Zhang. less
PLoS One, 2013 Apr 18; 8(4). PMID: 23593433 Free PMC article.
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IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R.
Christopher E Martin, Ester M M van Leeuwen, +3 authors, Se Jin Im, Derry C Roopenian, Young-Chul Sung, Charles D Surh. less
Blood, 2013 Apr 24; 121(22). PMID: 23610371 Free PMC article.
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Human FcγRII cytoplasmic domains differentially influence antibody-mediated dengue virus infection.
Kobporn Boonnak, Bonnie M Slike, Gina C Donofrio, Mary A Marovich.
J Immunol, 2013 Apr 26; 190(11). PMID: 23616574 Free PMC article.
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Human Fc receptor-like 5 binds intact IgG via mechanisms distinct from those of Fc receptors.
Andrea Franco, Bazarragchaa Damdinsuren, +4 authors, Tomoko Ise, Jessica Dement-Brown, Huifang Li, Satoshi Nagata, Mate Tolnay. less
J Immunol, 2013 Apr 26; 190(11). PMID: 23616577 Free PMC article.
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No evidence that soluble TACI induces signalling via membrane-expressed BAFF and APRIL in myeloid cells.
Josquin Nys, Cristian R Smulski, +6 authors, Aubry Tardivel, Laure Willen, Christine Kowalczyk, Olivier Donzé, Bertrand Huard, Henry Hess, Pascal Schneider. less
PLoS One, 2013 Apr 27; 8(4). PMID: 23620746 Free PMC article.
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The B cell helper side of neutrophils.
Andrea Cerutti, Irene Puga, Giuliana Magri.
J Leukoc Biol, 2013 May 01; 94(4). PMID: 23630389 Free PMC article.
Review.
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A single-dose PLGA encapsulated protective antigen domain 4 nanoformulation protects mice against Bacillus anthracis spore challenge.
Manish Manish, Amit Rahi, +2 authors, Manpreet Kaur, Rakesh Bhatnagar, Samer Singh. less
PLoS One, 2013 May 03; 8(4). PMID: 23637922 Free PMC article.
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Inhibition of HPA-1a alloantibody-mediated platelet destruction by a deglycosylated anti-HPA-1a monoclonal antibody in mice: toward targeted treatment of fetal-alloimmune thrombocytopenia.
Tamam Bakchoul, Andreas Greinacher, +6 authors, Ulrich J Sachs, Annika Krautwurst, Harald Renz, Habi Harb, Gregor Bein, Peter J Newman, Sentot Santoso. less
Blood, 2013 May 07; 122(3). PMID: 23645838 Free PMC article.
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Targeting natural killer cells to acute myeloid leukemia in vitro with a CD16 x 33 bispecific killer cell engager and ADAM17 inhibition.
Andres Wiernik, Bree Foley, +9 authors, Bin Zhang, Michael R Verneris, Erica Warlick, Michelle K Gleason, Julie A Ross, Xianghua Luo, Daniel J Weisdorf, Bruce Walcheck, Daniel A Vallera, Jeffrey S Miller. less
Clin Cancer Res, 2013 May 22; 19(14). PMID: 23690482 Free PMC article.
Highly Cited.
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Dengue virus neutralization in cells expressing Fc gamma receptors.
Tanu Chawla, Kuan Rong Chan, +4 authors, Summer L Zhang, Hwee Cheng Tan, Angeline P C Lim, Brendon J Hanson, Eng Eong Ooi. less
PLoS One, 2013 May 30; 8(5). PMID: 23717696 Free PMC article.
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Engineered antibody Fc variant with selectively enhanced FcγRIIb binding over both FcγRIIa(R131) and FcγRIIa(H131).
F Mimoto, H Katada, +7 authors, S Kadono, T Igawa, T Kuramochi, M Muraoka, Y Wada, K Haraya, T Miyazaki, K Hattori. less
Protein Eng Des Sel, 2013 Jun 08; 26(10). PMID: 23744091 Free PMC article.
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Inflammatory monocytes and Fcγ receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice.
Michaela Seeling, Ulrike Hillenhoff, +4 authors, Jean Pierre David, Georg Schett, Jan Tuckermann, Anja Lux, Falk Nimmerjahn. less
Proc Natl Acad Sci U S A, 2013 Jun 12; 110(26). PMID: 23754379 Free PMC article.
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T and B lymphocytes in the brains of dogs with concomitant seropositivity to three pathogenic protozoans: Leishmania chagasi, Toxoplasma gondii and Neospora caninum.
Keila Priscilla Sakamoto, Guilherme Dias de Melo, Gisele Fabrino Machado.
BMC Res Notes, 2013 Jun 14; 6. PMID: 23758819 Free PMC article.
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Analytical FcRn affinity chromatography for functional characterization of monoclonal antibodies.
Tilman Schlothauer, Petra Rueger, +9 authors, Jan Olaf Stracke, Hubert Hertenberger, Felix Fingas, Lothar Kling, Thomas Emrich, Georg Drabner, Stefan Seeber, Johannes Auer, Stefan Koch, Apollon Papadimitriou. less
MAbs, 2013 Jun 15; 5(4). PMID: 23765230 Free PMC article.
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The Wnt signaling pathway is involved in the regulation of phagocytosis of virus in Drosophila.
Fei Zhu, Xiaobo Zhang.
Sci Rep, 2013 Jun 26; 3. PMID: 23797713 Free PMC article.
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B Cell in Autoimmune Diseases.
Christiane S Hampe.
Scientifica (Cairo), 2012 Jan 01; 2012. PMID: 23807906 Free PMC article.
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Membrane-type 6 matrix metalloproteinase regulates the activation-induced downmodulation of CD16 in human primary NK cells.
Giovanna Peruzzi, Laurette Femnou, +4 authors, Aleksandra Gil-Krzewska, Francisco Borrego, Jennifer Weck, Konrad Krzewski, John E Coligan. less
J Immunol, 2013 Jul 16; 191(4). PMID: 23851692 Free PMC article.
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Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma.
Tyler R Simpson, Fubin Li, +11 authors, Welby Montalvo-Ortiz, Manuel A Sepulveda, Katharina Bergerhoff, Frederick Arce, Claire Roddie, Jake Y Henry, Hideo Yagita, Jedd D Wolchok, Karl S Peggs, Jeffrey V Ravetch, James P Allison, Sergio A Quezada. less
J Exp Med, 2013 Jul 31; 210(9). PMID: 23897981 Free PMC article.
Highly Cited.
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Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies.
Yannick Bulliard, Rose Jolicoeur, +6 authors, Maurice Windman, Sarah M Rue, Seth Ettenberg, Deborah A Knee, Nicholas S Wilson, Glenn Dranoff, Jennifer L Brogdon. less
J Exp Med, 2013 Jul 31; 210(9). PMID: 23897982 Free PMC article.
Highly Cited.
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Tpl2 kinase regulates FcγR signaling and immune thrombocytopenia in mice.
Irene Kyrmizi, Marianna Ioannou, +3 authors, Maria Hatziapostolou, Philip N Tsichlis, Dimitrios T Boumpas, Ioannis Tassiulas. less
J Leukoc Biol, 2013 Jul 31; 94(4). PMID: 23898046 Free PMC article.
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Acute inflammation primes myeloid effector cells for anti-inflammatory STAT6 signaling.
Fredrik Wermeling, Robert M Anthony, Frank Brombacher, Jeffrey V Ravetch.
Proc Natl Acad Sci U S A, 2013 Jul 31; 110(33). PMID: 23898202 Free PMC article.
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High-dose methylprednisolone pulse therapy upregulated FcγRIIb expression on B cells in primary Sjögren's syndrome patients with thrombocytopenia.
Haifeng Chen, Shiliang Zhou, +3 authors, Dinglei Su, Liwei Lu, Xia Li, Lingyun Sun. less
Clin Rheumatol, 2013 Aug 07; 32(12). PMID: 23917390
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Immunomagnetic enrichment and flow cytometric characterization of mouse microglia.
Supinder S Bedi, Philippa Smith, +2 authors, Robert A Hetz, Hasen Xue, Charles S Cox. less
J Neurosci Methods, 2013 Aug 10; 219(1). PMID: 23928152 Free PMC article.
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Lessons for the clinic from rituximab pharmacokinetics and pharmacodynamics.
Josée Golay, Gianpietro Semenzato, +8 authors, Alessandro Rambaldi, Robin Foà, Gianluca Gaidano, Enrica Gamba, Fabrizio Pane, Antonello Pinto, Giorgina Specchia, Francesco Zaja, Mario Regazzi. less
MAbs, 2013 Aug 13; 5(6). PMID: 23933992 Free PMC article.
Review.
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Clinical presentation, pathogenesis, diagnosis, and treatment of epidermolysis bullosa acquisita.
Ralf J Ludwig.
ISRN Dermatol, 2013 Aug 21; 2013. PMID: 23956869 Free PMC article.
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Fc-gamma receptor polymorphisms as predictive and prognostic factors in patients receiving oncolytic adenovirus treatment.
Mari Hirvinen, Raita Heiskanen, +6 authors, Minna Oksanen, Saila Pesonen, Ilkka Liikanen, Timo Joensuu, Anna Kanerva, Vincenzo Cerullo, Akseli Hemminki. less
J Transl Med, 2013 Aug 24; 11. PMID: 23965133 Free PMC article.
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Ankylosing spondylitis: from cells to genes.
José Francisco Zambrano-Zaragoza, Juan Manuel Agraz-Cibrian, +2 authors, Christian González-Reyes, Ma de Jesús Durán-Avelar, Norberto Vibanco-Pérez. less
Int J Inflam, 2013 Aug 24; 2013. PMID: 23970995 Free PMC article.
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Fcγ receptors enable anticancer action of proapoptotic and immune-modulatory antibodies.
Jeong M Kim, Avi Ashkenazi.
J Exp Med, 2013 Aug 28; 210(9). PMID: 23980122 Free PMC article.
Review.
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Involvement of antibody-dependent cell-mediated cytotoxicity in inflammatory demyelination in a mouse model of neuromyelitis optica.
Julien Ratelade, Nithi Asavapanumas, +3 authors, Alanna M Ritchie, Scott Wemlinger, Jeffrey L Bennett, A S Verkman. less
Acta Neuropathol, 2013 Sep 03; 126(5). PMID: 23995423 Free PMC article.
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Intravenous immunoglobulin-mediated immunosuppression and the development of an IVIG substitute.
Miglena G Prabagar, Hyeong-jwa Choi, +2 authors, Jin-Yeon Park, Sohee Loh, Young-Sun Kang. less
Clin Exp Med, 2013 Sep 03; 14(4). PMID: 23996469
Review.
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Molecular basis for downregulation of C5a-mediated inflammation by IgG1 immune complexes in allergy and asthma.
Manoj Kumar Pandey.
Curr Allergy Asthma Rep, 2013 Sep 10; 13(6). PMID: 24013944
Review.
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No Association between FC γ R3B Copy Number Variation and Susceptibility to Biopsy-Proven Giant Cell Arteritis.
Emma Dunstan, Sue Lester, +4 authors, Rachel Black, Maureen Rischmueller, Helen Chan, Alex W Hewitt, Catherine L Hill. less
Arthritis, 2013 Sep 13; 2013. PMID: 24027635 Free PMC article.
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To fuse or not to fuse: what is your purpose?
Mark R Bell, Mark J Engleka, Asim Malik, James E Strickler.
Protein Sci, 2013 Sep 17; 22(11). PMID: 24038604 Free PMC article.
Review.
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Comparative efficiency of HIV-1-infected T cell killing by NK cells, monocytes and neutrophils.
Adjoa Smalls-Mantey, Mark Connors, Quentin J Sattentau.
PLoS One, 2013 Sep 17; 8(9). PMID: 24040353 Free PMC article.
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RON receptor tyrosine kinase, a negative regulator of inflammation, is decreased during simian immunodeficiency virus-associated central nervous system disease.
Daniele C Cary, Janice E Clements, Andrew J Henderson.
J Immunol, 2013 Sep 18; 191(8). PMID: 24043899 Free PMC article.
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Glycoepitopes of staphylococcal wall teichoic acid govern complement-mediated opsonophagocytosis via human serum antibody and mannose-binding lectin.
Kenji Kurokawa, Dong-Jun Jung, +12 authors, Jang-Hyun An, Katharina Fuchs, Yu-Jin Jeon, Na-Hyang Kim, Xuehua Li, Koichiro Tateishi, Ji Ae Park, Guoqing Xia, Misao Matsushita, Kazue Takahashi, Hee-Ju Park, Andreas Peschel, Bok Luel Lee. less
J Biol Chem, 2013 Sep 21; 288(43). PMID: 24045948 Free PMC article.
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B cell-regulated immune responses in tumor models and cancer patients.
Carlo Fremd, Florian Schuetz, +2 authors, Christof Sohn, Philipp Beckhove, Christoph Domschke. less
Oncoimmunology, 2013 Sep 28; 2(7). PMID: 24073382 Free PMC article.
Review.
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Retargeting T cells for HER2-positive tumor killing by a bispecific Fv-Fc antibody.
Lei Wang, Yanran He, +7 authors, Ge Zhang, Juan Ma, Changzhen Liu, Wen He, Wei Wang, Huamin Han, Bhargavi M Boruah, Bin Gao. less
PLoS One, 2013 Oct 03; 8(9). PMID: 24086580 Free PMC article.
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Meningococcal disease and the complement system.
Lisa A Lewis, Sanjay Ram.
Virulence, 2013 Oct 10; 5(1). PMID: 24104403 Free PMC article.
Review.
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Exocytosis acts as a modulator of the ILT4-mediated inhibition of neutrophil functions.
Jeremy Baudhuin, Julie Migraine, +4 authors, Valerie Faivre, Laure Loumagne, Anne-Claire Lukaszewicz, Didier Payen, Benoit Favier. less
Proc Natl Acad Sci U S A, 2013 Oct 18; 110(44). PMID: 24133137 Free PMC article.
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Investigating monoclonal antibody aggregation using a combination of H/DX-MS and other biophysical measurements.
Roxana E Iacob, George M Bou-Assaf, +3 authors, Lee Makowski, John R Engen, Steven A Berkowitz, Damian Houde. less
J Pharm Sci, 2013 Oct 19; 102(12). PMID: 24136070 Free PMC article.
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The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus.
Rachael Keating, Tomer Hertz, +12 authors, Marie Wehenkel, Tarsha L Harris, Benjamin A Edwards, Jennifer L McClaren, Scott A Brown, Sherri Surman, Zachary S Wilson, Philip Bradley, Julia Hurwitz, Hongbo Chi, Peter C Doherty, Paul G Thomas, Maureen A McGargill. less
Nat Immunol, 2013 Oct 22; 14(12). PMID: 24141387 Free PMC article.
Highly Cited.
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Opportunities to exploit non-neutralizing HIV-specific antibody activity.
Margaret E Ackerman, Galit Alter.
Curr HIV Res, 2013 Nov 07; 11(5). PMID: 24191934 Free PMC article.
Review.
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Fc receptor-mediated immune responses: new tools but increased complexity in HIV prevention.
Diego A Vargas-Inchaustegui, Marjorie Robert-Guroff.
Curr HIV Res, 2013 Nov 07; 11(5). PMID: 24191937 Free PMC article.
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Epitope specificity of human immunodeficiency virus-1 antibody dependent cellular cytotoxicity [ADCC] responses.
Justin Pollara, Mattia Bonsignori, +3 authors, M Anthony Moody, Marzena Pazgier, Barton F Haynes, Guido Ferrari. less
Curr HIV Res, 2013 Nov 07; 11(5). PMID: 24191939 Free PMC article.
Review.
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Antitumor activities of agonistic anti-TNFR antibodies require differential FcγRIIB coengagement in vivo.
Fubin Li, Jeffrey V Ravetch.
Proc Natl Acad Sci U S A, 2013 Nov 13; 110(48). PMID: 24218606 Free PMC article.
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HLA-DQA1 and PLA2R1 polymorphisms and risk of idiopathic membranous nephropathy.
Gemma Bullich, José Ballarín, +6 authors, Artur Oliver, Nadia Ayasreh, Irene Silva, Sheila Santín, Montserrat M Díaz-Encarnación, Roser Torra, Elisabet Ars. less
Clin J Am Soc Nephrol, 2013 Nov 23; 9(2). PMID: 24262501 Free PMC article.
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Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease.
Zsuzsanna Tucsek, Peter Toth, +7 authors, Danuta Sosnowska, Tripti Gautam, Matthew Mitschelen, Akos Koller, Gabor Szalai, William E Sonntag, Zoltan Ungvari, Anna Csiszar. less
J Gerontol A Biol Sci Med Sci, 2013 Nov 26; 69(10). PMID: 24269929 Free PMC article.
Highly Cited.
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Enhancement of anti-tumor CD8 immunity by IgG1-mediated targeting of Fc receptors.
Scott N Furlan, Rajakumar Mandraju, +6 authors, Travis Brewer, Kole Roybal, Ty Dale Troutman, Wei Hu, Noah W Palm, Arun Unni, Chandrashekhar Pasare. less
MAbs, 2013 Nov 29; 6(1). PMID: 24284965 Free PMC article.
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Cutting edge: Expression of FcγRIIB tempers memory CD8 T cell function in vivo.
Gabriel R Starbeck-Miller, Vladimir P Badovinac, Daniel L Barber, John T Harty.
J Immunol, 2013 Nov 29; 192(1). PMID: 24285839 Free PMC article.
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Asymmetrical Fc engineering greatly enhances antibody-dependent cellular cytotoxicity (ADCC) effector function and stability of the modified antibodies.
Zhi Liu, Kannan Gunasekaran, +10 authors, Wei Wang, Vladimir Razinkov, Laura Sekirov, Esther Leng, Heather Sweet, Ian Foltz, Monique Howard, Anne-Marie Rousseau, Carl Kozlosky, William Fanslow, Wei Yan. less
J Biol Chem, 2013 Dec 07; 289(6). PMID: 24311787 Free PMC article.
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Liquid-liquid diffusion crystallization improves the X-ray diffraction of EndoS, an endo-β-N-acetylglucosaminidase from Streptococcus pyogenes with activity on human IgG.
Beatriz Trastoy, Joseph V Lomino, Lai Xi Wang, Eric J Sundberg.
Acta Crystallogr Sect F Struct Biol Cryst Commun, 2013 Dec 10; 69(Pt 12). PMID: 24316841 Free PMC article.
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Early IFN-gamma production after YF 17D vaccine virus immunization in mice and its association with adaptive immune responses.
Patrícia C C Neves, Juliana R Santos, +2 authors, Luciana N Tubarão, Myrna C Bonaldo, Ricardo Galler. less
PLoS One, 2013 Dec 11; 8(12). PMID: 24324734 Free PMC article.
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Glycosylation of immunoglobulin g: role of genetic and epigenetic influences.
Cristina Menni, Toma Keser, +11 authors, Massimo Mangino, Jordana T Bell, Idil Erte, Irena Akmačić, Frano Vučković, Maja Pučić Baković, Olga Gornik, Mark I McCarthy, Vlatka Zoldoš, Tim D Spector, Gordan Lauc, Ana M Valdes. less
PLoS One, 2013 Dec 11; 8(12). PMID: 24324808 Free PMC article.
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Fcγ receptor upregulation is associated with immune complex inflammation in the mouse retina and early age-related macular degeneration.
Salome Murinello, Robert F Mullins, +2 authors, Andrew J Lotery, V Hugh Perry, Jessica L Teeling. less
Invest Ophthalmol Vis Sci, 2013 Dec 18; 55(1). PMID: 24334446 Free PMC article.
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Genetic dissection of dendritic cell homeostasis and function: lessons from cell type-specific gene ablation.
Peer W F Karmaus, Hongbo Chi.
Cell Mol Life Sci, 2013 Dec 25; 71(10). PMID: 24366237 Free PMC article.
Review.
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Recombinant IgG2a Fc (M045) multimers effectively suppress experimental autoimmune myasthenia gravis.
Muthusamy Thiruppathi, Jian Rong Sheng, +2 authors, Liangcheng Li, Bellur S Prabhakar, Matthew N Meriggioli. less
J Autoimmun, 2014 Jan 07; 52. PMID: 24388113 Free PMC article.
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Yersinia pestis: mechanisms of entry into and resistance to the host cell.
Yuehua Ke, Zeliang Chen, Ruifu Yang.
Front Cell Infect Microbiol, 2014 Jan 09; 3. PMID: 24400226 Free PMC article.
Review.
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Human IgG Fc domain engineering enhances antitoxin neutralizing antibody activity.
Stylianos Bournazos, Siu-Kei Chow, +2 authors, Nareen Abboud, Arturo Casadevall, Jeffrey V Ravetch. less
J Clin Invest, 2014 Jan 10; 124(2). PMID: 24401277 Free PMC article.
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Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo.
David J DiLillo, Gene S Tan, Peter Palese, Jeffrey V Ravetch.
Nat Med, 2014 Jan 15; 20(2). PMID: 24412922 Free PMC article.
Highly Cited.
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Chemical and chemoenzymatic synthesis of glycoproteins for deciphering functions.
Lai-Xi Wang, Mohammed N Amin.
Chem Biol, 2014 Jan 21; 21(1). PMID: 24439206 Free PMC article.
Review.
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CD19 and CD32b differentially regulate human B cell responsiveness.
Jodi L Karnell, Nazzareno Dimasi, +7 authors, Fredrick G Karnell, Ryan Fleming, Ellen Kuta, Mildred Wilson, Herren Wu, Changshou Gao, Ronald Herbst, Rachel Ettinger. less
J Immunol, 2014 Jan 21; 192(4). PMID: 24442430 Free PMC article.
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The function of Fcγ receptors in dendritic cells and macrophages.
Martin Guilliams, Pierre Bruhns, +2 authors, Yvan Saeys, Hamida Hammad, Bart N Lambrecht. less
Nat Rev Immunol, 2014 Jan 22; 14(2). PMID: 24445665
Highly Cited. Review.
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Whole Pichia pastoris yeast expressing measles virus nucleoprotein as a production and delivery system to multimerize Plasmodium antigens.
Daria Jacob, Claude Ruffie, +11 authors, Myriam Dubois, Chantal Combredet, Rogerio Amino, Pauline Formaglio, Olivier Gorgette, Gérard Pehau-Arnaudet, Charline Guery, Odile Puijalon, Jean-Christophe Barale, Robert Ménard, Frédéric Tangy, Monica Sala. less
PLoS One, 2014 Jan 30; 9(1). PMID: 24475165 Free PMC article.
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Increasing FcγRIIa affinity of an FcγRIII-optimized anti-EGFR antibody restores neutrophil-mediated cytotoxicity.
Stefanie Derer, Pia Glorius, +7 authors, Martin Schlaeth, Stefan Lohse, Katja Klausz, Umesh Muchhal, John R Desjarlais, Andreas Humpe, Thomas Valerius, Matthias Peipp. less
MAbs, 2014 Feb 05; 6(2). PMID: 24492248 Free PMC article.
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Effects of altered FcγR binding on antibody pharmacokinetics in cynomolgus monkeys.
Maya K Leabman, Y Gloria Meng, +3 authors, Robert F Kelley, Laura E DeForge, Kyra J Cowan, Suhasini Iyer. less
MAbs, 2014 Feb 05; 5(6). PMID: 24492343 Free PMC article.
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Respiratory syncytial virus persistence in macrophages upregulates Fcgamma receptors expression.
Jorge Gaona, Carlos Santiago-Olivares, Enrique Ortega, Beatriz Gómez.
Viruses, 2014 Feb 11; 6(2). PMID: 24509813 Free PMC article.
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The biology of NK cells and their receptors affects clinical outcomes after hematopoietic cell transplantation (HCT).
Bree Foley, Martin Felices, +3 authors, Frank Cichocki, Sarah Cooley, Michael R Verneris, Jeffrey S Miller. less
Immunol Rev, 2014 Feb 13; 258(1). PMID: 24517425 Free PMC article.
Review.
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Fcγ receptor-mediated inflammation inhibits axon regeneration.
Gang Zhang, Nataliia Bogdanova, +4 authors, Tong Gao, Julia J Song, Mark S Cragg, Martin J Glennie, Kazim A Sheikh. less
PLoS One, 2014 Feb 14; 9(2). PMID: 24523933 Free PMC article.
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Structural insights on the role of antibodies in HIV-1 vaccine and therapy.
Anthony P West, Louise Scharf, +3 authors, Johannes F Scheid, Florian Klein, Pamela J Bjorkman, Michel C Nussenzweig. less
Cell, 2014 Feb 18; 156(4). PMID: 24529371 Free PMC article.
Highly Cited. Review.
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An Fc domain protein-small molecule conjugate as an enhanced immunomodulator.
Meng-Jung Chiang, Marc A Holbert, +14 authors, Jay H Kalin, Young-Hoon Ahn, John Giddens, Mohammed N Amin, Martin S Taylor, Samuel L Collins, Yee Chan-Li, Adam Waickman, Po-Yuan Hsiao, David Bolduc, Daniel J Leahy, Maureen R Horton, Lai-Xi Wang, Jonathan D Powell, Philip A Cole. less
J Am Chem Soc, 2014 Feb 19; 136(9). PMID: 24533830 Free PMC article.
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Inhibitory Fcγ receptor is required for the maintenance of tolerance through distinct mechanisms.
Fubin Li, Patrick Smith, Jeffrey V Ravetch.
J Immunol, 2014 Feb 25; 192(7). PMID: 24563255 Free PMC article.
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Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA.
Juan Carlos Almagro, Gary L Gilliland, +21 authors, Felix Breden, Jamie K Scott, Devin Sok, Matthias Pauthner, Janice M Reichert, Gustavo Helguera, Raiees Andrabi, Robert Mabry, Mathieu Bléry, James E Voss, Juha Laurén, Lubna Abuqayyas, Stefan Barghorn, Eshel Ben-Jacob, James E Crowe, James S Huston, Stephen Albert Johnston, Eric Krauland, Fridtjof Lund-Johansen, Wayne A Marasco, Paul W H I Parren, Kai Y Xu. less
MAbs, 2014 Mar 05; 6(3). PMID: 24589717 Free PMC article.
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Direct neutralization of type III effector translocation by the variable region of a monoclonal antibody to Yersinia pestis LcrV.
Maya I Ivanov, Jim Hill, James B Bliska.
Clin Vaccine Immunol, 2014 Mar 07; 21(5). PMID: 24599533 Free PMC article.
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Current and Potential Uses of Immunocytokines as Cancer Immunotherapy.
Paul M Sondel, Stephen D Gillies.
Antibodies (Basel), 2012 Jul 04; 1(2). PMID: 24634778 Free PMC article.
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Natural autoantibodies to Fcγ receptors in intravenous immunoglobulins.
Hicham Bouhlal, Denis Martinvalet, +5 authors, Jean-Luc Teillaud, Catherine Fridman, Michel D Kazatchkine, Jagadeesh Bayry, Sébastien Lacroix-Desmazes, Srini V Kaveri. less
J Clin Immunol, 2014 Apr 01; 34 Suppl 1. PMID: 24682714
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Persistent lung inflammation and fibrosis in serum amyloid P component (APCs-/-) knockout mice.
Darrell Pilling, Richard H Gomer.
PLoS One, 2014 Apr 04; 9(4). PMID: 24695531 Free PMC article.
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Chemoenzymatic Fc glycosylation via engineered aldehyde tags.
Elizabeth L Smith, John P Giddens, +3 authors, Anthony T Iavarone, Kamil Godula, Lai-Xi Wang, Carolyn R Bertozzi. less
Bioconjug Chem, 2014 Apr 08; 25(4). PMID: 24702330 Free PMC article.
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Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering.
Limin Shang, Bruno Daubeuf, +21 authors, Martha Triantafilou, Robin Olden, Fabien Dépis, Anne-Catherine Raby, Suzanne Herren, Anaelle Dos Santos, Pauline Malinge, Irene Dunn-Siegrist, Sanae Benmkaddem, Antoine Geinoz, Giovanni Magistrelli, François Rousseau, Vanessa Buatois, Susana Salgado-Pires, Walter Reith, Renato Monteiro, Jérôme Pugin, Olivier Leger, Walter Ferlin, Marie Kosco-Vilbois, Kathy Triantafilou, Greg Elson. less
J Biol Chem, 2014 Apr 17; 289(22). PMID: 24737331 Free PMC article.
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Antigen cross-presentation of immune complexes.
Barbara Platzer, Madeleine Stout, Edda Fiebiger.
Front Immunol, 2014 Apr 20; 5. PMID: 24744762 Free PMC article.
Review.
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Development of a cell-based assay measuring the activation of FcγRIIa for the characterization of therapeutic monoclonal antibodies.
Minoru Tada, Akiko Ishii-Watabe, Takuo Suzuki, Nana Kawasaki.
PLoS One, 2014 Apr 23; 9(4). PMID: 24752341 Free PMC article.
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Inhibition of murine fibrocyte differentiation by cross-linked IgG is dependent on FcγRI.
Darrell Pilling, Jeffrey R Crawford, J Sjef Verbeek, Richard H Gomer.
J Leukoc Biol, 2014 Apr 23; 96(2). PMID: 24752483 Free PMC article.
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Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies.
Beatriz Trastoy, Joseph V Lomino, +8 authors, Brian G Pierce, Lester G Carter, Sebastian Günther, John P Giddens, Greg A Snyder, Thomas M Weiss, Zhiping Weng, Lai-Xi Wang, Eric J Sundberg. less
Proc Natl Acad Sci U S A, 2014 Apr 23; 111(18). PMID: 24753590 Free PMC article.
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Fcγ receptor III and Fcγ receptor IV on macrophages drive autoimmune valvular carditis in mice.
Patricia M Hobday, Jennifer L Auger, +3 authors, Gregory R Schuneman, Stefanie Haasken, J Sjef Verbeek, Bryce A Binstadt. less
Arthritis Rheumatol, 2014 Apr 24; 66(4). PMID: 24757138 Free PMC article.
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Targeting B cells and autoantibodies in the therapy of autoimmune diseases.
Daniela Kao, Anja Lux, Inessa Schwab, Falk Nimmerjahn.
Semin Immunopathol, 2014 Apr 30; 36(3). PMID: 24777745
Review.
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Antibody-mediated enhancement of parvovirus B19 uptake into endothelial cells mediated by a receptor for complement factor C1q.
Kristina von Kietzell, Tanja Pozzuto, +3 authors, Regine Heilbronn, Tobias Grössl, Henry Fechner, Stefan Weger. less
J Virol, 2014 May 09; 88(14). PMID: 24807719 Free PMC article.
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Fc receptors for immunoglobulins and their appearance during vertebrate evolution.
Srinivas Akula, Sayran Mohammadamin, Lars Hellman.
PLoS One, 2014 May 13; 9(5). PMID: 24816777 Free PMC article.
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Suppression of innate and adaptive B cell activation pathways by antibody coengagement of FcγRIIb and CD19.
Dániel Szili, Marcell Cserhalmi, +3 authors, Zsuzsanna Bankó, György Nagy, David E Szymkowski, Gabriella Sármay. less
MAbs, 2014 May 16; 6(4). PMID: 24828435 Free PMC article.
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Single-domain antibodies targeting neuraminidase protect against an H5N1 influenza virus challenge.
Francisco Miguel Cardoso, Lorena Itatí Ibañez, +9 authors, Silvie Van den Hoecke, Sarah De Baets, Anouk Smet, Kenny Roose, Bert Schepens, Francis J Descamps, Walter Fiers, Serge Muyldermans, Ann Depicker, Xavier Saelens. less
J Virol, 2014 May 16; 88(15). PMID: 24829341 Free PMC article.
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Primer on tumor immunology and cancer immunotherapy.
Timothy J Harris, Charles G Drake.
J Immunother Cancer, 2013 Jan 01; 1. PMID: 24829749 Free PMC article.
Review.
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Role of Fc-mediated antibody function in protective immunity against HIV-1.
George K Lewis.
Immunology, 2014 May 21; 142(1). PMID: 24843871 Free PMC article.
Review.
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B cells and humoral immunity in atherosclerosis.
Dimitrios Tsiantoulas, Cody J Diehl, Joseph L Witztum, Christoph J Binder.
Circ Res, 2014 May 24; 114(11). PMID: 24855199 Free PMC article.
Highly Cited. Review.
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The Fab conformations in the solution structure of human immunoglobulin G4 (IgG4) restrict access to its Fc region: implications for functional activity.
Lucy E Rayner, Gar Kay Hui, +3 authors, Jayesh Gor, Richard K Heenan, Paul A Dalby, Stephen J Perkins. less
J Biol Chem, 2014 May 31; 289(30). PMID: 24876381 Free PMC article.
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Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirus.
Ming Shum Yip, Nancy Hiu Lan Leung, +6 authors, Chung Yan Cheung, Ping Hung Li, Horace Hok Yeung Lee, Marc Daëron, Joseph Sriyal Malik Peiris, Roberto Bruzzone, Martial Jaume. less
Virol J, 2014 Jun 03; 11. PMID: 24885320 Free PMC article.
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Investigating perturbed pathway modules from gene expression data via structural equation models.
Daniele Pepe, Mario Grassi.
BMC Bioinformatics, 2014 Jun 03; 15. PMID: 24885496 Free PMC article.
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Glycans - the third revolution in evolution.
Gordan Lauc, Jasminka Krištić, Vlatka Zoldoš.
Front Genet, 2014 Jun 07; 5. PMID: 24904645 Free PMC article.
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Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies.
Caitlin Gillis, Aurélie Gouel-Chéron, Friederike Jönsson, Pierre Bruhns.
Front Immunol, 2014 Jun 10; 5. PMID: 24910634 Free PMC article.
Review.
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Actin cytoskeleton reorganization by Syk regulates Fcγ receptor responsiveness by increasing its lateral mobility and clustering.
Valentin Jaumouillé, Yoav Farkash, +3 authors, Khuloud Jaqaman, Raibatak Das, Clifford A Lowell, Sergio Grinstein. less
Dev Cell, 2014 Jun 11; 29(5). PMID: 24914558 Free PMC article.
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Neurobiology of microglial action in CNS injuries: receptor-mediated signaling mechanisms and functional roles.
Xiaoming Hu, Anthony K F Liou, +7 authors, Rehana K Leak, Mingyue Xu, Chengrui An, Jun Suenaga, Yejie Shi, Yanqin Gao, Ping Zheng, Jun Chen. less
Prog Neurobiol, 2014 Jun 14; 119-120. PMID: 24923657 Free PMC article.
Review.
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Dual role for Fcγ receptors in host defense and disease in Borrelia burgdorferi-infected mice.
Alexia A Belperron, Nengyin Liu, Carmen J Booth, Linda K Bockenstedt.
Front Cell Infect Microbiol, 2014 Jun 27; 4. PMID: 24967215 Free PMC article.
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Dengue virus infection induces expansion of a CD14(+)CD16(+) monocyte population that stimulates plasmablast differentiation.
Marcin Kwissa, Helder I Nakaya, +8 authors, Nattawat Onlamoon, Jens Wrammert, Francois Villinger, Guey Chuen Perng, Sutee Yoksan, Kovit Pattanapanyasat, Kulkanya Chokephaibulkit, Rafi Ahmed, Bali Pulendran. less
Cell Host Microbe, 2014 Jul 02; 16(1). PMID: 24981333 Free PMC article.
Highly Cited.
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Association studies of Fcγ receptor polymorphisms with outcome in HER2+ breast cancer patients treated with trastuzumab in NCCTG (Alliance) Trial N9831.
Nadine Norton, Rebecca M Olson, +5 authors, Mark Pegram, Kathleen Tenner, Karla V Ballman, Raphael Clynes, Keith L Knutson, Edith A Perez. less
Cancer Immunol Res, 2014 Jul 06; 2(10). PMID: 24989892 Free PMC article.
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Enhanced auto-antibody production and Mott cell formation in FcμR-deficient autoimmune mice.
Kazuhito Honjo, Yoshiki Kubagawa, +5 authors, Yusuke Suzuki, Miyuki Takagi, Hiroshi Ohno, R Pat Bucy, Shozo Izui, Hiromi Kubagawa. less
Int Immunol, 2014 Jul 06; 26(12). PMID: 24994818 Free PMC article.
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Prolonged antigen presentation by immune complex-binding dendritic cells programs the proliferative capacity of memory CD8 T cells.
Beatriz León, André Ballesteros-Tato, Troy D Randall, Frances E Lund.
J Exp Med, 2014 Jul 09; 211(8). PMID: 25002751 Free PMC article.
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Defunctioning polymorphism in the immunoglobulin G inhibitory receptor (FcγRIIB-T/T232) does not impact on kidney transplant or recipient survival.
Menna R Clatworthy, Rebeccah J Matthews, +3 authors, Bernd Doehler, Lisa C Willcocks, Gerhard Opelz, Kenneth G C Smith. less
Transplantation, 2014 Jul 16; 98(3). PMID: 25022320 Free PMC article.
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Distinct Fcγ receptors mediate the effect of serum amyloid p on neutrophil adhesion and fibrocyte differentiation.
Nehemiah Cox, Darrell Pilling, Richard H Gomer.
J Immunol, 2014 Jul 16; 193(4). PMID: 25024390 Free PMC article.
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Scavenger receptor function of mouse Fcγ receptor III contributes to progression of atherosclerosis in apolipoprotein E hyperlipidemic mice.
Xinmei Zhu, Hang Pong Ng, +4 authors, Yen-Chun Lai, Jodi K Craigo, Pruthvi S Nagilla, Pooja Raghani, Shanmugam Nagarajan. less
J Immunol, 2014 Jul 20; 193(5). PMID: 25038257 Free PMC article.
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Independent evolution of Fc- and Fab-mediated HIV-1-specific antiviral antibody activity following acute infection.
Anne-Sophie Dugast, Leonidas Stamatatos, +8 authors, Andrew Tonelli, Todd J Suscovich, Anna F Licht, Iliyana Mikell, Margaret E Ackerman, Hendrik Streeck, P J Klasse, John P Moore, Galit Alter. less
Eur J Immunol, 2014 Jul 22; 44(10). PMID: 25043633 Free PMC article.
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Phenotypic expression in human monocyte-derived interleukin-4-induced foreign body giant cells and macrophages in vitro: dependence on material surface properties.
Amy K McNally, James M Anderson.
J Biomed Mater Res A, 2014 Jul 22; 103(4). PMID: 25045023 Free PMC article.
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Type I and type II Fc receptors regulate innate and adaptive immunity.
Andrew Pincetic, Stylianos Bournazos, +5 authors, David J DiLillo, Jad Maamary, Taia T Wang, Rony Dahan, Benjamin-Maximillian Fiebiger, Jeffrey V Ravetch. less
Nat Immunol, 2014 Jul 22; 15(8). PMID: 25045879 Free PMC article.
Highly Cited. Review.
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CD64 expression is increased in patients with severe acute pancreatitis: clinical significance.
Hao Zhang, Xian-Long Ling, +5 authors, Yu-Yun Wu, Mu-Han Lü, Hong Guo, Peng-Bin Zhang, Xiao-Yan Zhao, Shi-Ming Yang. less
Gut Liver, 2014 Jul 30; 8(4). PMID: 25071912 Free PMC article.
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Silencing Bruton's tyrosine kinase in alveolar neutrophils protects mice from LPS/immune complex-induced acute lung injury.
Agnieszka Krupa, Marek Fol, +10 authors, Moshiur Rahman, Karen Y Stokes, Jon M Florence, Igor L Leskov, Mikhail V Khoretonenko, Michael A Matthay, Kathleen D Liu, Carolyn S Calfee, Amy Tvinnereim, Gabriel R Rosenfield, Anna K Kurdowska. less
Am J Physiol Lung Cell Mol Physiol, 2014 Aug 03; 307(6). PMID: 25085625 Free PMC article.
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FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial.
Shuying S Li, Peter B Gilbert, +31 authors, Georgia D Tomaras, Gustavo Kijak, Guido Ferrari, Rasmi Thomas, Chul-Woo Pyo, Susan Zolla-Pazner, David Montefiori, Hua-Xin Liao, Gary Nabel, Abraham Pinter, David T Evans, Raphael Gottardo, James Y Dai, Holly Janes, Daryl Morris, Youyi Fong, Paul T Edlefsen, Fusheng Li, Nicole Frahm, Michael D Alpert, Heather Prentice, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Jaranit Kaewkungwal, Sorachai Nitayaphan, Merlin L Robb, Robert J O'Connell, Barton F Haynes, Nelson L Michael, Jerome H Kim, M Juliana McElrath, Daniel E Geraghty. less
J Clin Invest, 2014 Aug 12; 124(9). PMID: 25105367 Free PMC article.
Highly Cited.
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Human gene copy number variation and infectious disease.
Edward J Hollox, Boon-Peng Hoh.
Hum Genet, 2014 Aug 12; 133(10). PMID: 25110110
Review.
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Enhanced neonatal Fc receptor function improves protection against primate SHIV infection.
Sung-Youl Ko, Amarendra Pegu, +18 authors, Rebecca S Rudicell, Zhi-yong Yang, M Gordon Joyce, Xuejun Chen, Keyun Wang, Saran Bao, Thomas D Kraemer, Timo Rath, Ming Zeng, Stephen D Schmidt, John-Paul Todd, Scott R Penzak, Kevin O Saunders, Martha C Nason, Ashley T Haase, Srinivas S Rao, Richard S Blumberg, John R Mascola, Gary J Nabel. less
Nature, 2014 Aug 15; 514(7524). PMID: 25119033 Free PMC article.
Highly Cited.
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Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice.
Ariel Halper-Stromberg, Ching-Lan Lu, +13 authors, Florian Klein, Joshua A Horwitz, Stylianos Bournazos, Lilian Nogueira, Thomas R Eisenreich, Cassie Liu, Anna Gazumyan, Uwe Schaefer, Rebecca C Furze, Michael S Seaman, Rab Prinjha, Alexander Tarakhovsky, Jeffrey V Ravetch, Michel C Nussenzweig. less
Cell, 2014 Aug 19; 158(5). PMID: 25131989 Free PMC article.
Highly Cited.
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Atheroprotective immunization with malondialdehyde-modified LDL is hapten specific and dependent on advanced MDA adducts: implications for development of an atheroprotective vaccine.
Ayelet Gonen, Lotte F Hansen, +12 authors, William W Turner, Erica N Montano, Xuchu Que, Apaїs Rafia, Meng-Yun Chou, Philipp Wiesner, Dimitrios Tsiantoulas, Maripat Corr, Michael S VanNieuwenhze, Sotirios Tsimikas, Christoph J Binder, Joseph L Witztum, Karsten Hartvigsen. less
J Lipid Res, 2014 Aug 22; 55(10). PMID: 25143462 Free PMC article.
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Delineating the importance of serum opsonins and the bacterial capsule in affecting the uptake and killing of Burkholderia pseudomallei by murine neutrophils and macrophages.
Minal Mulye, Michael P Bechill, +3 authors, William Grose, Viviana P Ferreira, Eric R Lafontaine, R Mark Wooten. less
PLoS Negl Trop Dis, 2014 Aug 22; 8(8). PMID: 25144195 Free PMC article.
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Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function.
Amy W Chung, Max Crispin, +8 authors, Laura Pritchard, Hannah Robinson, Miroslaw K Gorny, Xiaojie Yu, Chris Bailey-Kellogg, Margaret E Ackerman, Chris Scanlan, Susan Zolla-Pazner, Galit Alter. less
AIDS, 2014 Aug 28; 28(17). PMID: 25160934 Free PMC article.
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New roles for Fc receptors in neurodegeneration-the impact on Immunotherapy for Alzheimer's Disease.
James P Fuller, Jeffrey B Stavenhagen, Jessica L Teeling.
Front Neurosci, 2014 Sep 06; 8. PMID: 25191216 Free PMC article.
Review.
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Age-related macular degeneration in the aspect of chronic low-grade inflammation (pathophysiological parainflammation).
Małgorzata Nita, Andrzej Grzybowski, Francisco J Ascaso, Valentín Huerva.
Mediators Inflamm, 2014 Sep 13; 2014. PMID: 25214719 Free PMC article.
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Functions of Antibodies.
Donald N Forthal.
Microbiol Spectr, 2014 Sep 13; 2(4). PMID: 25215264 Free PMC article.
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Universal antibody conjugation to nanoparticles using the Fcγ receptor I (FcγRI): quantitative profiling of membrane biomarkers.
Chloe Kim, Justin F Galloway, Kwan Hyi Lee, Peter C Searson.
Bioconjug Chem, 2014 Sep 13; 25(10). PMID: 25215471 Free PMC article.
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The Role of FcRn in Antigen Presentation.
Kristi Baker, Timo Rath, Michal Pyzik, Richard S Blumberg.
Front Immunol, 2014 Sep 16; 5. PMID: 25221553 Free PMC article.
Review.
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Therapeutic blockade of LIGHT interaction with herpesvirus entry mediator and lymphotoxin β receptor attenuates in vivo cytotoxic allogeneic responses.
Maria-Luisa del Rio, Carlos Fernandez-Renedo, +6 authors, Stefanie Scheu, Klaus Pfeffer, Yasushi Shintani, Mitchell Kronenberg, Olivier Chaloin, Pascal Schneider, Jose-Ignacio Rodriguez-Barbosa. less
Transplantation, 2014 Sep 17; 98(11). PMID: 25226173 Free PMC article.
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Maternal antibodies: clinical significance, mechanism of interference with immune responses, and possible vaccination strategies.
Stefan Niewiesk.
Front Immunol, 2014 Oct 04; 5. PMID: 25278941 Free PMC article.
Highly Cited. Review.
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CMV-encoded Fcγ receptors: modulators at the interface of innate and adaptive immunity.
Eugenia Corrales-Aguilar, Katja Hoffmann, Hartmut Hengel.
Semin Immunopathol, 2014 Oct 08; 36(6). PMID: 25288477
Review.
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The mechanism of phagocytosis: two stages of engulfment.
David M Richards, Robert G Endres.
Biophys J, 2014 Oct 09; 107(7). PMID: 25296306 Free PMC article.
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Role of B cells and antibodies in acquired immunity against Mycobacterium tuberculosis.
Jacqueline M Achkar, John Chan, Arturo Casadevall.
Cold Spring Harb Perspect Med, 2014 Oct 11; 5(3). PMID: 25301934 Free PMC article.
Review.
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The Amazing Transglycosylation Activity of Endo-β-N-acetylglucosaminidases.
Lai-Xi Wang.
Trends Glycosci Glycotechnol, 2011 Jan 01; 23(129). PMID: 25309039 Free PMC article.
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Immune complexes inhibit IL-1 secretion and inflammasome activation.
John R Janczy, Ceren Ciraci, +4 authors, Stefanie Haasken, Yoichiro Iwakura, Alicia K Olivier, Suzanne L Cassel, Fayyaz S Sutterwala. less
J Immunol, 2014 Oct 17; 193(10). PMID: 25320279 Free PMC article.
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Dichotomy in FcγRIIB deficiency and autoimmune-prone SLAM haplotype clarifies the roles of the Fc receptor in development of autoantibodies and glomerulonephritis.
Yasuyoshi Kanari, Akiko Sugahara-Tobinai, +4 authors, Haruka Takahashi, Masanori Inui, Akira Nakamura, Sachiko Hirose, Toshiyuki Takai. less
BMC Immunol, 2014 Oct 24; 15. PMID: 25339546 Free PMC article.
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Fc gamma receptor IIb on GM-CSF macrophages controls immune complex mediated inhibition of inflammatory signals.
Kim C M Santegoets, Mark H Wenink, Wim B van den Berg, Timothy R D J Radstake.
PLoS One, 2014 Oct 24; 9(10). PMID: 25340460 Free PMC article.
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Development of non-viral vehicles for targeted gene transfer into microglia via the integrin receptor CD11b.
Markus Smolny, Mary-Louise Rogers, +2 authors, Anthony Shafton, Robert A Rush, Martin J Stebbing. less
Front Mol Neurosci, 2014 Oct 28; 7. PMID: 25346658 Free PMC article.
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IgG1 protects against renal disease in a mouse model of cryoglobulinaemia.
Richard T Strait, Monica T Posgai, +11 authors, Ashley Mahler, Nathaniel Barasa, Chaim O Jacob, Jörg Köhl, Marc Ehlers, Keith Stringer, Shiva Kumar Shanmukhappa, David Witte, Md Monir Hossain, Marat Khodoun, Andrew B Herr, Fred D Finkelman. less
Nature, 2014 Nov 05; 517(7535). PMID: 25363774 Free PMC article.
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IgG receptor FcγRIIB plays a key role in obesity-induced hypertension.
Nathan C Sundgren, Wanpen Vongpatanasin, +5 authors, Brigid-Meghan D Boggan, Keiji Tanigaki, Ivan S Yuhanna, Ken L Chambliss, Chieko Mineo, Philip W Shaul. less
Hypertension, 2014 Nov 05; 65(2). PMID: 25368023 Free PMC article.
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Investigating the interaction between the neonatal Fc receptor and monoclonal antibody variants by hydrogen/deuterium exchange mass spectrometry.
Pernille Foged Jensen, Vincent Larraillet, +3 authors, Tilman Schlothauer, Hubert Kettenberger, Maximiliane Hilger, Kasper D Rand. less
Mol Cell Proteomics, 2014 Nov 08; 14(1). PMID: 25378534 Free PMC article.
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Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages.
Lisa T C Vogelpoel, Ivo S Hansen, +8 authors, Theo Rispens, Femke J M Muller, Toni M M van Capel, Maureen C Turina, Joost B Vos, Dominique L P Baeten, Martien L Kapsenberg, Esther C de Jong, Jeroen den Dunnen. less
Nat Commun, 2014 Nov 14; 5. PMID: 25392121 Free PMC article.
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Antibody-dependent enhancement infection facilitates dengue virus-regulated signaling of IL-10 production in monocytes.
Tsung-Ting Tsai, Yi-Jui Chuang, +5 authors, Yee-Shin Lin, Chih-Peng Chang, Shu-Wen Wan, Sheng-Hsiang Lin, Chia-Ling Chen, Chiou-Feng Lin. less
PLoS Negl Trop Dis, 2014 Nov 21; 8(11). PMID: 25412261 Free PMC article.
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Genetic Susceptibility to ANCA-Associated Vasculitis: State of the Art.
Francesco Bonatti, Michele Reina, Tauro Maria Neri, Davide Martorana.
Front Immunol, 2014 Dec 03; 5. PMID: 25452756 Free PMC article.
Review.
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The role of B cells and humoral immunity in Mycobacterium tuberculosis infection.
John Chan, Simren Mehta, +4 authors, Sushma Bharrhan, Yong Chen, Jacqueline M Achkar, Arturo Casadevall, JoAnne Flynn. less
Semin Immunol, 2014 Dec 03; 26(6). PMID: 25458990 Free PMC article.
Review.
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HIV-1 CD4-induced (CD4i) gp120 epitope vaccines promote B and T-cell responses that contribute to reduced viral loads in rhesus macaques.
Michael A Thomas, Iskra Tuero, +13 authors, Thorsten Demberg, Diego A Vargas-Inchaustegui, Thomas Musich, Peng Xiao, David Venzon, Celia LaBranche, David C Montefiori, Janet DiPasquale, Steven G Reed, Anthony DeVico, Timothy Fouts, George K Lewis, Robert C Gallo, Marjorie Robert-Guroff. less
Virology, 2014 Dec 03; 471-473. PMID: 25461534 Free PMC article.
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Clinical severity of visceral leishmaniasis is associated with changes in immunoglobulin g fc N-glycosylation.
Luiz Gustavo Gardinassi, Viktoria Dotz, +8 authors, Agnes Hipgrave Ederveen, Roque Pacheco de Almeida, Carlos Henrique Nery Costa, Dorcas Lamounier Costa, Amélia Ribeiro de Jesus, Oleg A Mayboroda, Gustavo Rocha Garcia, Manfred Wuhrer, Isabel Kinney Ferreira de Miranda Santos. less
mBio, 2014 Dec 04; 5(6). PMID: 25467439 Free PMC article.
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FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis.
Menna R Clatworthy, Sarah K Harford, Rebeccah J Mathews, Kenneth G C Smith.
Proc Natl Acad Sci U S A, 2014 Dec 06; 111(50). PMID: 25475856 Free PMC article.
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Gut microbiota elicits a protective immune response against malaria transmission.
Bahtiyar Yilmaz, Silvia Portugal, +12 authors, Tuan M Tran, Raffaella Gozzelino, Susana Ramos, Joana Gomes, Ana Regalado, Peter J Cowan, Anthony J F d'Apice, Anita S Chong, Ogobara K Doumbo, Boubacar Traore, Peter D Crompton, Henrique Silveira, Miguel P Soares. less
Cell, 2014 Dec 07; 159(6). PMID: 25480293 Free PMC article.
Highly Cited.
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IgG4 can induce an M2-like phenotype in human monocyte-derived macrophages through FcγRI.
Jennifer F A Swisher, Devin A Haddad, +2 authors, Anna G McGrath, Gunther H Boekhoudt, Gerald M Feldman. less
MAbs, 2014 Dec 09; 6(6). PMID: 25484046 Free PMC article.
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A general strategy for generating intact, full-length IgG antibodies that penetrate into the cytosol of living cells.
Dong-Ki Choi, Jeomil Bae, +3 authors, Seung-Min Shin, Ju-Yeon Shin, Sunghoon Kim, Yong-Sung Kim. less
MAbs, 2014 Dec 09; 6(6). PMID: 25484049 Free PMC article.
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Protein A-neutralizing monoclonal antibody protects neonatal mice against Staphylococcus aureus.
Vilasack Thammavongsa, Sabine Rauch, +2 authors, Hwan Keun Kim, Dominique M Missiakas, Olaf Schneewind. less
Vaccine, 2014 Dec 10; 33(4). PMID: 25488332 Free PMC article.
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Detection of true IgE-expressing mouse B lineage cells.
Michael P Gallagher, Akritee Shrestha, Jennifer M Magee, Duane R Wesemann.
J Vis Exp, 2014 Dec 10; (94). PMID: 25490087 Free PMC article.
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Chemically synthesized molecules with the targeting and effector functions of antibodies.
Patrick J McEnaney, Kelly J Fitzgerald, +5 authors, Andrew X Zhang, Eugene F Douglass, Weifang Shan, Aaron Balog, Mariya D Kolesnikova, David A Spiegel. less
J Am Chem Soc, 2014 Dec 17; 136(52). PMID: 25514603 Free PMC article.
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Monomeric IgG1 Fc molecules displaying unique Fc receptor interactions that are exploitable to treat inflammation-mediated diseases.
Tianlei Ying, Yang Feng, +2 authors, Yanping Wang, Weizao Chen, Dimiter S Dimitrov. less
MAbs, 2014 Dec 18; 6(5). PMID: 25517305 Free PMC article.
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A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies.
Jan Stracke, Thomas Emrich, +11 authors, Petra Rueger, Tilman Schlothauer, Lothar Kling, Alexander Knaupp, Hubert Hertenberger, Andreas Wolfert, Christian Spick, Wilma Lau, Georg Drabner, Ulrike Reiff, Hans Koll, Apollon Papadimitriou. less
MAbs, 2014 Dec 18; 6(5). PMID: 25517308 Free PMC article.
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A monoclonal antibody against hinge-cleaved IgG restores effector function to proteolytically-inactivated IgGs in vitro and in vivo.
Randall J Brezski, Michelle Kinder, +9 authors, Katharine D Grugan, Keri L Soring, Jill Carton, Allison R Greenplate, Theodore Petley, Dorie Capaldi, Kerry Brosnan, Eva Emmell, Sharon Watson, Robert E Jordan. less
MAbs, 2014 Dec 18; 6(5). PMID: 25517311 Free PMC article.
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Fc-dependent mechanisms of action: roles of FcγR and FcRn.
T Kuijpers.
Clin Exp Immunol, 2014 Dec 30; 178 Suppl 1. PMID: 25546775 Free PMC article.
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De-functioning polymorphism in the inhibitory receptor FcγRIIB does not impact upon kidney allograft survival.
M R Clatworthy, R Matthews, +3 authors, B Doehler, L Willcocks, G Opelz, K G C Smith. less
Clin Exp Immunol, 2014 Dec 30; 178 Suppl 1. PMID: 25546804 Free PMC article.
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Rational clinical trial design for antibody mediated renal allograft injury.
Shaifali Sandal, Martin S Zand.
Front Biosci (Landmark Ed), 2015 Jan 02; 20(4). PMID: 25553476 Free PMC article.
Review.
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Induced expression of FcγRIIIa (CD16a) on CD4+ T cells triggers generation of IFN-γhigh subset.
Anil K Chauhan, Chen Chen, Terry L Moore, Richard J DiPaolo.
J Biol Chem, 2015 Jan 06; 290(8). PMID: 25556651 Free PMC article.
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The high-affinity human IgG receptor Fc gamma receptor I (FcγRI) is not associated with vascular leakage of dengue.
Zaiharina Mohamad Zamberi, Zuraihan Zakaria, +6 authors, Abu Thalhah Abdul Aziz, Benedict Sim Lim Heng, Masliza Zaid, Christopher Lee Kwok Chong, Fadzilah Mohd Noor, Sazaly Abu Bakar, Hoh Boon Peng. less
J Negat Results Biomed, 2015 Jan 09; 14. PMID: 25566870 Free PMC article.
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Requirement for Fc effector mechanisms in the APOBEC3/Rfv3-dependent neutralizing antibody response.
Kalani Halemano, Bradley S Barrett, +2 authors, Karl J Heilman, Thomas E Morrison, Mario L Santiago. less
J Virol, 2015 Jan 16; 89(7). PMID: 25589647 Free PMC article.
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Fcγ receptors and ligands and cardiovascular disease.
Keiji Tanigaki, Nathan Sundgren, +3 authors, Amit Khera, Wanpen Vongpatanasin, Chieko Mineo, Philip W Shaul. less
Circ Res, 2015 Jan 17; 116(2). PMID: 25593280 Free PMC article.
Review.
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A comparison of assays for accurate copy number measurement of the low-affinity Fc gamma receptor genes FCGR3A and FCGR3B.
Umi Shakina Haridan, Umairah Mokhtar, +11 authors, Lee R Machado, Abu Thalhah Abdul Aziz, Rafidah Hanim Shueb, Masliza Zaid, Benedict Sim, Mahiran Mustafa, Nik Khairudin Nik Yusof, Christopher K C Lee, Suhaili Abu Bakar, Sazaly AbuBakar, Edward J Hollox, Hoh Boon Peng. less
PLoS One, 2015 Jan 17; 10(1). PMID: 25594501 Free PMC article.
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Unique ligand-binding property of the human IgM Fc receptor.
Kazuhito Honjo, Yoshiki Kubagawa, John F Kearney, Hiromi Kubagawa.
J Immunol, 2015 Jan 21; 194(4). PMID: 25601920 Free PMC article.
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Neuronal Fc gamma receptor I as a novel mediator for IgG immune complex-induced peripheral sensitization.
Lintao Qu.
Neural Regen Res, 2012 Sep 15; 7(26). PMID: 25624839 Free PMC article.
Review.
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The presence of FCGR2B promoter or transmembrane region variant alleles leads to reduced serum IL-6 levels in rheumatoid arthritis.
Stefanie Meister, Robby Engelmann, Christian Kneitz, Brigitte Müller-Hilke.
Rheumatol Int, 2015 Jan 30; 35(8). PMID: 25630523
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Macrophages are critical effectors of antibody therapies for cancer.
Kipp Weiskopf, Irving L Weissman.
MAbs, 2015 Feb 11; 7(2). PMID: 25667985 Free PMC article.
Highly Cited. Review.
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Antibody effector functions mediated by Fcγ-receptors are compromised during persistent viral infection.
Andreas Wieland, Rangaiah Shashidharamurthy, +9 authors, Alice O Kamphorst, Jin-Hwan Han, Rachael D Aubert, Biswa P Choudhury, Sean R Stowell, Junghwa Lee, George A Punkosdy, Mark J Shlomchik, Periasamy Selvaraj, Rafi Ahmed. less
Immunity, 2015 Feb 15; 42(2). PMID: 25680276 Free PMC article.
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Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection.
Douglas H Yamada, Heidi Elsaesser, +5 authors, Anja Lux, John M Timmerman, Sherie L Morrison, Juan Carlos de la Torre, Falk Nimmerjahn, David G Brooks. less
Immunity, 2015 Feb 15; 42(2). PMID: 25680277 Free PMC article.
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B cells and antibodies in the defense against Mycobacterium tuberculosis infection.
Jacqueline M Achkar, John Chan, Arturo Casadevall.
Immunol Rev, 2015 Feb 24; 264(1). PMID: 25703559 Free PMC article.
Highly Cited. Review.
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Neutralization of (NK-cell-derived) B-cell activating factor by Belimumab restores sensitivity of chronic lymphoid leukemia cells to direct and Rituximab-induced NK lysis.
J Wild, B J Schmiedel, +6 authors, A Maurer, S Raab, L Prokop, S Stevanović, D Dörfel, P Schneider, H R Salih. less
Leukemia, 2015 Feb 25; 29(8). PMID: 25710310
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Clinical characteristics of male and female Korean patients with systemic lupus erythematosus: a comparative study.
Jiwon Hwang, Jaejoon Lee, +3 authors, Joong Kyoung Ahn, Eun-Jung Park, Hoon-Suk Cha, Eun-Mi Koh. less
Korean J Intern Med, 2015 Mar 10; 30(2). PMID: 25750567 Free PMC article.
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Control of cytokine production by human fc gamma receptors: implications for pathogen defense and autoimmunity.
Lisa T C Vogelpoel, Dominique L P Baeten, Esther C de Jong, Jeroen den Dunnen.
Front Immunol, 2015 Mar 12; 6. PMID: 25759693 Free PMC article.
Review.
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Metabolic control of B cells: more questions than answers.
Melania Capasso, Alaa Rashed Alyahyawi, Sarah Spear.
Front Immunol, 2015 Mar 13; 6. PMID: 25762999 Free PMC article.
Review.
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The long pentraxin PTX3 promotes fibrocyte differentiation.
Darrell Pilling, Nehemiah Cox, +2 authors, Varsha Vakil, J Sjef Verbeek, Richard H Gomer. less
PLoS One, 2015 Mar 17; 10(3). PMID: 25774777 Free PMC article.
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Reduced Atherosclerosis in apoE-inhibitory FcγRIIb-Deficient Mice Is Associated With Increased Anti-Inflammatory Responses by T Cells and Macrophages.
Hang Pong Ng, Xinmei Zhu, +2 authors, Erin Y Harmon, Michelle R Lennartz, Shanmugam Nagarajan. less
Arterioscler Thromb Vasc Biol, 2015 Mar 21; 35(5). PMID: 25792447 Free PMC article.
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Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells.
Yawu Jing, Zhenya Ni, +4 authors, Jianming Wu, LeeAnn Higgins, Todd W Markowski, Dan S Kaufman, Bruce Walcheck. less
PLoS One, 2015 Mar 31; 10(3). PMID: 25816339 Free PMC article.
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Immune complexes regulate bone metabolism through FcRγ signalling.
Takako Negishi-Koga, Hans-Jürgen Gober, +8 authors, Eriko Sumiya, Noriko Komatsu, Kazuo Okamoto, Shinichiro Sawa, Ayako Suematsu, Tomomi Suda, Kojiro Sato, Toshiyuki Takai, Hiroshi Takayanagi. less
Nat Commun, 2015 Apr 01; 6. PMID: 25824719
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Siglec receptors impact mammalian lifespan by modulating oxidative stress.
Flavio Schwarz, Oliver M T Pearce, +14 authors, Xiaoxia Wang, Annie N Samraj, Heinz Läubli, Javier O Garcia, Hongqiao Lin, Xiaoming Fu, Andrea Garcia-Bingman, Patrick Secrest, Casey E Romanoski, Charles Heyser, Christopher K Glass, Stanley L Hazen, Nissi Varki, Ajit Varki, Pascal Gagneux. less
Elife, 2015 Apr 08; 4. PMID: 25846707 Free PMC article.
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Variation at FCGR2A and functionally related genes is associated with the response to anti-TNF therapy in rheumatoid arthritis.
Gabriela Avila-Pedretti, Jesús Tornero, +14 authors, Antonio Fernández-Nebro, Francisco Blanco, Isidoro González-Alvaro, Juan D Cañete, Joan Maymó, Mercedes Alperiz, Benjamín Fernández-Gutiérrez, Alex Olivé, Héctor Corominas, Alba Erra, Adrià Aterido, María López Lasanta, Raül Tortosa, Antonio Julià, Sara Marsal. less
PLoS One, 2015 Apr 08; 10(4). PMID: 25848939 Free PMC article.
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A Bivalent, Chimeric Rabies Virus Expressing Simian Immunodeficiency Virus Envelope Induces Multifunctional Antibody Responses.
Amber Dunkel, Shixue Shen, +2 authors, Celia C LaBranche, David Montefiori, James P McGettigan. less
AIDS Res Hum Retroviruses, 2015 Apr 08; 31(11). PMID: 25848984 Free PMC article.
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Inflammatory bowel disease associates with proinflammatory potential of the immunoglobulin G glycome.
Irena Trbojević Akmačić, Nicholas T Ventham, +16 authors, Evropi Theodoratou, Frano Vučković, Nicholas A Kennedy, Jasminka Krištić, Elaine R Nimmo, Rahul Kalla, Hazel Drummond, Jerko Štambuk, Malcolm G Dunlop, Mislav Novokmet, Yurii Aulchenko, Olga Gornik, Harry Campbell, Maja Pučić Baković, Jack Satsangi, Gordan Lauc, IBD-BIOM Consortium. less
Inflamm Bowel Dis, 2015 Apr 22; 21(6). PMID: 25895110 Free PMC article.
Highly Cited.
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Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils.
K Thomsen, L Christophersen, +3 authors, T Bjarnsholt, P Ø Jensen, C Moser, N Høiby. less
Infect Immun, 2015 Apr 22; 83(7). PMID: 25895968 Free PMC article.
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C-reactive protein directly suppresses Th1 cell differentiation and alleviates experimental autoimmune encephalomyelitis.
Lin Zhang, Shan-Hui Liu, +7 authors, Tyler T Wright, Zhi-Yuan Shen, Hai-Yun Li, Wei Zhu, Lawrence A Potempa, Shang-Rong Ji, Alexander J Szalai, Yi Wu. less
J Immunol, 2015 Apr 29; 194(11). PMID: 25917100 Free PMC article.
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Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients.
Emanuela Romano, Monika Kusio-Kobialka, +7 authors, Periklis G Foukas, Petra Baumgaertner, Christiane Meyer, Pierluigi Ballabeni, Olivier Michielin, Benjamin Weide, Pedro Romero, Daniel E Speiser. less
Proc Natl Acad Sci U S A, 2015 Apr 29; 112(19). PMID: 25918390 Free PMC article.
Highly Cited.
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Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI.
Masato Kiyoshi, Jose M M Caaveiro, +5 authors, Takeaki Kawai, Shinya Tashiro, Teruhiko Ide, Yoshiharu Asaoka, Kouta Hatayama, Kouhei Tsumoto. less
Nat Commun, 2015 May 01; 6. PMID: 25925696 Free PMC article.
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Anti-Ganglioside Antibodies Induce Nodal and Axonal Injury via Fcγ Receptor-Mediated Inflammation.
Lan He, Gang Zhang, +2 authors, Weiqiang Liu, Tong Gao, Kazim A Sheikh. less
J Neurosci, 2015 May 01; 35(17). PMID: 25926454 Free PMC article.
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An Fc engineering approach that modulates antibody-dependent cytokine release without altering cell-killing functions.
Michelle Kinder, Allison R Greenplate, +2 authors, William R Strohl, Robert E Jordan, Randall J Brezski. less
MAbs, 2015 May 02; 7(3). PMID: 25933349 Free PMC article.
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FcRn: The Architect Behind the Immune and Nonimmune Functions of IgG and Albumin.
Michal Pyzik, Timo Rath, +2 authors, Wayne I Lencer, Kristi Baker, Richard S Blumberg. less
J Immunol, 2015 May 03; 194(10). PMID: 25934922 Free PMC article.
Highly Cited. Review.
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Intranasal and oral vaccination with protein-based antigens: advantages, challenges and formulation strategies.
Shujing Wang, Huiqin Liu, Xinyi Zhang, Feng Qian.
Protein Cell, 2015 May 07; 6(7). PMID: 25944045 Free PMC article.
Review.
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Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.
Felix Oden, Stephen F Marino, +11 authors, Janko Brand, Susanne Scheu, Cathleen Kriegel, Daniel Olal, Anna Takvorian, Jörg Westermann, Buket Yilmaz, Michael Hinz, Oliver Daumke, Uta E Höpken, Gerd Müller, Martin Lipp. less
Mol Oncol, 2015 May 09; 9(7). PMID: 25953704 Free PMC article.
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Downmodulation of vaccine-induced immunity and protection against the intracellular bacterium Francisella tularensis by the inhibitory receptor FcγRIIB.
Brian J Franz, Ying Li, +5 authors, Constantine Bitsaktsis, Bibiana V Iglesias, Giang Pham, Raju Sunagar, Sudeep Kumar, Edmund J Gosselin. less
J Immunol Res, 2015 May 12; 2015. PMID: 25961064 Free PMC article.
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Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium.
Edward Chaum, Christina S Winborn, Sujoy Bhattacharya.
Mamm Genome, 2015 May 13; 26(5-6). PMID: 25963977 Free PMC article.
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Is infant immunization by breastfeeding possible?
Valerie Verhasselt.
Philos Trans R Soc Lond B Biol Sci, 2015 May 13; 370(1671). PMID: 25964452 Free PMC article.
Review.
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Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect.
David J DiLillo, Jeffrey V Ravetch.
Cell, 2015 May 16; 161(5). PMID: 25976835 Free PMC article.
Highly Cited.
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Related Mechanisms of Antibody Somatic Hypermutation and Class Switch Recombination.
Joyce K Hwang, Frederick W Alt, Leng-Siew Yeap.
Microbiol Spectr, 2015 Jun 25; 3(1). PMID: 26104555 Free PMC article.
Review.
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DC-SIGN activation mediates the differential effects of SAP and CRP on the innate immune system and inhibits fibrosis in mice.
Nehemiah Cox, Darrell Pilling, Richard H Gomer.
Proc Natl Acad Sci U S A, 2015 Jun 25; 112(27). PMID: 26106150 Free PMC article.
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Distinct and synergistic roles of FcγRIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and autoimmunity.
Chetna Soni, Phillip P Domeier, +7 authors, Eric B Wong, Shwetank, Tahsin N Khan, Melinda J Elias, Stephanie L Schell, Aron E Lukacher, Timothy K Cooper, Ziaur S M Rahman. less
J Autoimmun, 2015 Jul 15; 63. PMID: 26162758 Free PMC article.
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Serum protein gamma-glutamyl hydrolase, Ig gamma-3 chain C region, and haptoglobin are associated with the syndromes of pulmonary tuberculosis in traditional Chinese medicine.
Ting-Ting Jiang, Chong Wang, +6 authors, Li-Liang Wei, Xiao-Mei Yu, Li-Ying Shi, Dan-Dan Xu, Zhong-Liang Chen, Ze-Peng Ping, Ji-Cheng Li. less
BMC Complement Altern Med, 2015 Jul 23; 15. PMID: 26198726 Free PMC article.
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Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities.
Masaki Kurogochi, Masako Mori, +12 authors, Kenji Osumi, Mami Tojino, Shu-Ichi Sugawara, Shou Takashima, Yuriko Hirose, Wataru Tsukimura, Mamoru Mizuno, Junko Amano, Akio Matsuda, Masahiro Tomita, Atsushi Takayanagi, Shin-Ichiro Shoda, Takashi Shirai. less
PLoS One, 2015 Jul 23; 10(7). PMID: 26200113 Free PMC article.
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Association of systemic lupus erythematosus with decreased immunosuppressive potential of the IgG glycome.
Frano Vučković, Jasminka Krištić, +25 authors, Ivan Gudelj, Maria Teruel, Toma Keser, Marija Pezer, Maja Pučić-Baković, Jerko Štambuk, Irena Trbojević-Akmačić, Clara Barrios, Tamara Pavić, Cristina Menni, Youxin Wang, Yong Zhou, Liufu Cui, Haicheng Song, Qiang Zeng, Xiuhua Guo, Bernardo A Pons-Estel, Paul McKeigue, Alan Leslie Patrick, Olga Gornik, Tim D Spector, Miroslav Harjaček, Marta Alarcon-Riquelme, Mariam Molokhia, Wei Wang, Gordan Lauc. less
Arthritis Rheumatol, 2015 Jul 23; 67(11). PMID: 26200652 Free PMC article.
Highly Cited.
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The Structural Role of Antibody N-Glycosylation in Receptor Interactions.
Ganesh P Subedi, Adam W Barb.
Structure, 2015 Jul 28; 23(9). PMID: 26211613 Free PMC article.
Highly Cited.
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Insights into the effector functions of human IgG3 in the context of an antibody targeting transferrin receptor 1.
Lai Sum Leoh, Tracy R Daniels-Wells, Otoniel Martínez-Maza, Manuel L Penichet.
Mol Immunol, 2015 Aug 02; 67(2 Pt B). PMID: 26232328 Free PMC article.
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Short Communication: Exploring Antibody Potential as Prophylactic/Therapeutic Strategies for Prevention of Early Mucosal HIV-1 Infection.
Bin Su, Maryse Peressin, +6 authors, Camille Ducloy, Julien Penichon, Luzia M Mayr, Géraldine Laumond, Sylvie Schmidt, Thomas Decoville, Christiane Moog. less
AIDS Res Hum Retroviruses, 2015 Aug 08; 31(11). PMID: 26252799 Free PMC article.
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Characterization of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori).
Minoru Tada, Ken-ichiro Tatematsu, +5 authors, Akiko Ishii-Watabe, Akira Harazono, Daisuke Takakura, Noritaka Hashii, Hideki Sezutsu, Nana Kawasaki. less
MAbs, 2015 Aug 12; 7(6). PMID: 26261057 Free PMC article.
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Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.
Helena Ågerstam, Christine Karlsson, +13 authors, Nils Hansen, Carl Sandén, Maria Askmyr, Sofia von Palffy, Carl Högberg, Marianne Rissler, Mark Wunderlich, Gunnar Juliusson, Johan Richter, Kjell Sjöström, Ravi Bhatia, James C Mulloy, Marcus Järås, Thoas Fioretos. less
Proc Natl Acad Sci U S A, 2015 Aug 12; 112(34). PMID: 26261316 Free PMC article.
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Mucosal B Cells Are Associated with Delayed SIV Acquisition in Vaccinated Female but Not Male Rhesus Macaques Following SIVmac251 Rectal Challenge.
Iskra Tuero, Venkatramanan Mohanram, +15 authors, Thomas Musich, Leia Miller, Diego A Vargas-Inchaustegui, Thorsten Demberg, David Venzon, Irene Kalisz, V S Kalyanaraman, Ranajit Pal, Maria Grazia Ferrari, Celia LaBranche, David C Montefiori, Mangala Rao, Monica Vaccari, Genoveffa Franchini, Susan W Barnett, Marjorie Robert-Guroff. less
PLoS Pathog, 2015 Aug 13; 11(8). PMID: 26267144 Free PMC article.
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The role of Fc-FcγR interactions in IgG-mediated microbial neutralization.
Stylianos Bournazos, David J DiLillo, Jeffrey V Ravetch.
J Exp Med, 2015 Aug 19; 212(9). PMID: 26282878 Free PMC article.
Highly Cited. Review.
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Isotype Diversification of IgG Antibodies to HIV Gag Proteins as a Therapeutic Vaccination Strategy for HIV Infection.
Martyn A French, Laila N Abudulai, Sonia Fernandez.
Vaccines (Basel), 2013 Jan 01; 1(3). PMID: 26344116 Free PMC article.
Review.
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Dissecting the Role of Anti-ganglioside Antibodies in Guillain-Barré Syndrome: an Animal Model Approach.
Pallavi Asthana, Joaquim Si Long Vong, +4 authors, Gajendra Kumar, Raymond Chuen-Chung Chang, Gang Zhang, Kazim A Sheikh, Chi Him Eddie Ma. less
Mol Neurobiol, 2015 Sep 17; 53(7). PMID: 26374552
Review.
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Deregulated Fcγ receptor expression in patients with CIDP.
Isaak Quast, Flavio Cueni, +2 authors, Falk Nimmerjahn, Björn Tackenberg, Jan D Lünemann. less
Neurol Neuroimmunol Neuroinflamm, 2015 Sep 18; 2(5). PMID: 26380354 Free PMC article.
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Elevated Membrane and Soluble CD64: A Novel Marker Reflecting Altered FcγR Function and Disease in Early Rheumatoid Arthritis That Can Be Regulated by Anti-Rheumatic Treatment.
Peter Matt, Ulla Lindqvist, Sandra Kleinau.
PLoS One, 2015 Sep 26; 10(9). PMID: 26406605 Free PMC article.
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Association between FCGR3B copy number variations and susceptibility to autoimmune diseases: a meta-analysis.
Young Ho Lee, Sang-Cheol Bae, +4 authors, Young Ho Seo, Jae-Hoon Kim, Sung Jae Choi, Jong Dae Ji, Gwan Gyu Song. less
Inflamm Res, 2015 Sep 27; 64(12). PMID: 26407570
Review.
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Cooperative and alternate functions for STIM1 and STIM2 in macrophage activation and in the context of inflammation.
Georgios Sogkas, David Stegner, +6 authors, Shahzad N Syed, Timo Vögtle, Eduard Rau, Britta Gewecke, Reinhold E Schmidt, Bernhard Nieswandt, Johannes Engelbert Gessner. less
Immun Inflamm Dis, 2015 Sep 30; 3(3). PMID: 26417434 Free PMC article.
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Testing the role of the FcγRIIB immunoreceptor tyrosine-based inhibitory motif in regulation of the B cell immune response.
Raja Vuyyuru, Shixue Shen, Tim Manser.
Immun Inflamm Dis, 2015 Sep 30; 3(3). PMID: 26417440 Free PMC article.
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Comparing the efficacy and neuroinflammatory potential of three anti-abeta antibodies.
James P Fuller, Jeffrey B Stavenhagen, +3 authors, Søren Christensen, Fredrik Kartberg, Martin J Glennie, Jessica L Teeling. less
Acta Neuropathol, 2015 Oct 05; 130(5). PMID: 26433971 Free PMC article.
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Importance of the Side Chain at Position 296 of Antibody Fc in Interactions with FcγRIIIa and Other Fcγ Receptors.
Yuya Isoda, Hirokazu Yagi, +5 authors, Tadashi Satoh, Mami Shibata-Koyama, Kazuhiro Masuda, Mitsuo Satoh, Koichi Kato, Shigeru Iida. less
PLoS One, 2015 Oct 09; 10(10). PMID: 26444434 Free PMC article.
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Tumor-binding antibodies and tumor immunity.
Yaron Carmi, Edgar G Engleman.
Oncotarget, 2015 Oct 13; 6(34). PMID: 26457878 Free PMC article.
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Fc receptors and their influence on efficacy of therapeutic antibodies for treatment of viral diseases.
Kuan Rong Chan, Eugenia Z Ong, Darren Z L Mok, Eng Eong Ooi.
Expert Rev Anti Infect Ther, 2015 Oct 16; 13(11). PMID: 26466016 Free PMC article.
Review.
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Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses.
Frederick W Holtsberg, Sergey Shulenin, +20 authors, Hong Vu, Katie A Howell, Sonal J Patel, Bronwyn Gunn, Marcus Karim, Jonathan R Lai, Julia C Frei, Elisabeth K Nyakatura, Larry Zeitlin, Robin Douglas, Marnie L Fusco, Jeffrey W Froude, Erica Ollmann Saphire, Andrew S Herbert, Ariel S Wirchnianski, Calli M Lear-Rooney, Galit Alter, John M Dye, Pamela J Glass, Kelly L Warfield, M Javad Aman. less
J Virol, 2015 Oct 16; 90(1). PMID: 26468533 Free PMC article.
Highly Cited.
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Protective Role of Rho Guanosine Diphosphate Dissociation Inhibitor, Ly-GDI, in Pulmonary Alveolitis.
Chunguang Yan, Ximo Wang, +3 authors, Yanlan Liu, Raja-Elie Abdulnour, Min Wu, Hongwei Gao. less
PLoS One, 2015 Oct 16; 10(10). PMID: 26469087 Free PMC article.
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Systemic Sclerosis Patients Present Alterations in the Expression of Molecules Involved in B-Cell Regulation.
Lilian Soto, Ashley Ferrier, +7 authors, Octavio Aravena, Elianet Fonseca, Jorge Berendsen, Andrea Biere, Daniel Bueno, Verónica Ramos, Juan Carlos Aguillón, Diego Catalán. less
Front Immunol, 2015 Oct 21; 6. PMID: 26483788 Free PMC article.
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A bone to pick with Fc gamma receptors.
Christian M Karsten, Jörg Köhl.
Ann Transl Med, 2015 Oct 22; 3(15). PMID: 26488014 Free PMC article.
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Association study of copy number variants in FCGR3A and FCGR3B gene with risk of ankylosing spondylitis in a Chinese population.
Li Wang, Xiao Yang, +11 authors, Guoqi Cai, Lihong Xin, Qing Xia, Xu Zhang, Xiaona Li, Mengmeng Wang, Kang Wang, Guo Xia, Shengqian Xu, Jianhua Xu, Yanfeng Zou, Faming Pan. less
Rheumatol Int, 2015 Oct 24; 36(3). PMID: 26494566
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Human IgG4: a structural perspective.
Anna M Davies, Brian J Sutton.
Immunol Rev, 2015 Oct 27; 268(1). PMID: 26497518 Free PMC article.
Review.
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TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity.
Stian Foss, Ruth Watkinson, +2 authors, Inger Sandlie, Leo C James, Jan Terje Andersen. less
Immunol Rev, 2015 Oct 27; 268(1). PMID: 26497531 Free PMC article.
Review.
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Structural insights into the interaction of human IgG1 with FcγRI: no direct role of glycans in binding.
Vaheh Oganesyan, Yariv Mazor, +8 authors, Chunning Yang, Kimberly E Cook, Robert M Woods, Andrew Ferguson, Michael A Bowen, Tom Martin, Jie Zhu, Herren Wu, William F Dall'Acqua. less
Acta Crystallogr D Biol Crystallogr, 2015 Nov 04; 71(Pt 11). PMID: 26527150 Free PMC article.
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Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells.
Derek D Sloan, Chia-Ying Kao Lam, +11 authors, Alivelu Irrinki, Liqin Liu, Angela Tsai, Craig S Pace, Jasmine Kaur, Jeffrey P Murry, Mini Balakrishnan, Paul A Moore, Syd Johnson, Jeffrey L Nordstrom, Tomas Cihlar, Scott Koenig. less
PLoS Pathog, 2015 Nov 06; 11(11). PMID: 26539983 Free PMC article.
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Mechanisms of antibody-mediated acute and chronic rejection of kidney allografts.
William M Baldwin, Anna Valujskikh, Robert L Fairchild.
Curr Opin Organ Transplant, 2015 Nov 18; 21(1). PMID: 26575854 Free PMC article.
Review.
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DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients.
Isabella C Hirako, Carolina Gallego-Marin, +10 authors, Marco A Ataide, Warrison A Andrade, Humberto Gravina, Bruno C Rocha, Rosane B de Oliveira, Dhelio B Pereira, Joseph Vinetz, Betty Diamond, Sanjay Ram, Douglas T Golenbock, Ricardo T Gazzinelli. less
mBio, 2015 Nov 19; 6(6). PMID: 26578679 Free PMC article.
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Synthesis of a Liposomal MUC1 Glycopeptide-Based Immunotherapeutic and Evaluation of the Effect of l-Rhamnose Targeting on Cellular Immune Responses.
Partha Karmakar, Kyunghee Lee, +2 authors, Sourav Sarkar, Katherine A Wall, Steven J Sucheck. less
Bioconjug Chem, 2015 Nov 26; 27(1). PMID: 26595674 Free PMC article.
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Generation of new peptide-Fc fusion proteins that mediate antibody-dependent cellular cytotoxicity against different types of cancer cells.
Mouldy Sioud, Phuong Westby, Julie Kristine E Olsen, Anne Mobergslien.
Mol Ther Methods Clin Dev, 2015 Nov 26; 2. PMID: 26605373 Free PMC article.
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Neutralizing Antibody Response and Antibody-Dependent Cellular Cytotoxicity in HIV-1-Infected Individuals from Guinea-Bissau and Denmark.
Marie Borggren, Sanne Skov Jensen, +8 authors, Leo Heyndrickx, Angelica A Palm, Jan Gerstoft, Gitte Kronborg, Bo Langhoff Hønge, Sanne Jespersen, Zacarias José da Silva, Ingrid Karlsson, Anders Fomsgaard. less
AIDS Res Hum Retroviruses, 2015 Dec 02; 32(5). PMID: 26621287 Free PMC article.
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Recent Advances in Kawasaki Disease.
Kyu Yeun Kim, Dong Soo Kim.
Yonsei Med J, 2015 Dec 04; 57(1). PMID: 26632378 Free PMC article.
Review.
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Antimicrobial Mechanisms of Macrophages and the Immune Evasion Strategies of Staphylococcus aureus.
Ronald S Flannagan, Bryan Heit, David E Heinrichs.
Pathogens, 2015 Dec 04; 4(4). PMID: 26633519 Free PMC article.
Review.
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Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells.
Stephanie Vogel, Elena Grabski, +12 authors, Daniela Buschjäger, Frank Klawonn, Marius Döring, Junxi Wang, Erika Fletcher, Ingo Bechmann, Torsten Witte, Martin Durisin, Burkhart Schraven, Sara M Mangsbo, Kurt Schönfeld, Niklas Czeloth, Ulrich Kalinke. less
Sci Rep, 2015 Dec 17; 5. PMID: 26670584 Free PMC article.
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SLE-associated risk factors affect DC function.
Myoungsun Son, Sun Jung Kim, Betty Diamond.
Immunol Rev, 2015 Dec 20; 269(1). PMID: 26683148 Free PMC article.
Review.
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A human monoclonal antibody against small envelope protein of hepatitis B virus with potent neutralization effect.
Wei Wang, Lina Sun, +11 authors, Tiansheng Li, Yanchun Ma, Jisu Li, Yang Liu, Meng Li, Lei Wang, Chuan Li, Youhua Xie, Yumei Wen, Mifang Liang, Li Chen, Shuping Tong. less
MAbs, 2015 Dec 30; 8(3). PMID: 26713590 Free PMC article.
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B cells with regulatory properties in transplantation tolerance.
Justine Durand, Elise Chiffoleau.
World J Transplant, 2016 Jan 02; 5(4). PMID: 26722647 Free PMC article.
Review.
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IgG4 Characteristics and Functions in Cancer Immunity.
Silvia Crescioli, Isabel Correa, +4 authors, Panagiotis Karagiannis, Anna M Davies, Brian J Sutton, Frank O Nestle, Sophia N Karagiannis. less
Curr Allergy Asthma Rep, 2016 Jan 09; 16(1). PMID: 26742760 Free PMC article.
Review.
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Validation of research trajectory 1 of an Exposome framework: Exposure to benzo(a)pyrene confers enhanced susceptibility to bacterial infection.
Ryan S Clark, Samuel T Pellom, +9 authors, Burthia Booker, Aramandla Ramesh, Tongwen Zhang, Anil Shanker, Mark Maguire, Paul D Juarez, Matthews-Juarez Patricia, Michael A Langston, Maureen Y Lichtveld, Darryl B Hood. less
Environ Res, 2016 Jan 15; 146. PMID: 26765097 Free PMC article.
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Recombinant factor VIII Fc (rFVIIIFc) fusion protein reduces immunogenicity and induces tolerance in hemophilia A mice.
Sriram Krishnamoorthy, Tongyao Liu, +8 authors, Douglas Drager, Susannah Patarroyo-White, Ekta Seth Chhabra, Robert Peters, Neil Josephson, David Lillicrap, Richard S Blumberg, Glenn F Pierce, Haiyan Jiang. less
Cell Immunol, 2016 Jan 18; 301. PMID: 26775174 Free PMC article.
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IgG Glycome in Colorectal Cancer.
Frano Vučković, Evropi Theodoratou, +14 authors, Kujtim Thaçi, Maria Timofeeva, Aleksandar Vojta, Jerko Štambuk, Maja Pučić-Baković, Pauline M Rudd, Lovorka Đerek, Dražen Servis, Annika Wennerström, Susan M Farrington, Markus Perola, Yurii Aulchenko, Malcolm G Dunlop, Harry Campbell, Gordan Lauc. less
Clin Cancer Res, 2016 Feb 03; 22(12). PMID: 26831718 Free PMC article.
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Identification of novel plasma glycosylation-associated markers of aging.
Mariangela Catera, Vincenzo Borelli, +10 authors, Nadia Malagolini, Mariella Chiricolo, Giulia Venturi, Celso A Reis, Hugo Osorio, Provvidenza M Abruzzo, Miriam Capri, Daniela Monti, Rita Ostan, Claudio Franceschi, Fabio Dall'Olio. less
Oncotarget, 2016 Feb 04; 7(7). PMID: 26840264 Free PMC article.
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Enhancing the safety of antibody-based immunomodulatory cancer therapy without compromising therapeutic benefit: Can we have our cake and eat it too?
Joseph M Ryan, Jeffrey S Wasser, Adam J Adler, Anthony T Vella.
Expert Opin Biol Ther, 2016 Feb 09; 16(5). PMID: 26855028 Free PMC article.
Review.
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Engineered IgG1-Fc--one fragment to bind them all.
Elisabeth Lobner, Michael W Traxlmayr, Christian Obinger, Christoph Hasenhindl.
Immunol Rev, 2016 Feb 13; 270(1). PMID: 26864108 Free PMC article.
Review.
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A hematopoietic cell-driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education.
Ning Wu, Ming-Chao Zhong, +7 authors, Romain Roncagalli, Luis-Alberto Pérez-Quintero, Huaijian Guo, Zhanguang Zhang, Christelle Lenoir, Zhongjun Dong, Sylvain Latour, André Veillette. less
Nat Immunol, 2016 Feb 16; 17(4). PMID: 26878112
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Prognostic relevance of HER2/neu in acute lymphoblastic leukemia and induction of NK cell reactivity against primary ALL blasts by trastuzumab.
Sebastian P Haen, Benjamin J Schmiedel, +7 authors, Kathrin Rothfelder, Bastian J Schmied, Truong-Minh Dang, Nora Mirza, Robert Möhle, Lothar Kanz, Wichard Vogel, Helmut R Salih. less
Oncotarget, 2016 Feb 18; 7(11). PMID: 26887048 Free PMC article.
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Potential Mechanisms for IgG4 Inhibition of Immediate Hypersensitivity Reactions.
Louisa K James, Stephen J Till.
Curr Allergy Asthma Rep, 2016 Feb 20; 16(3). PMID: 26892721 Free PMC article.
Review.
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Functional Role of FcγRIIB in the Regulation of Mesenchymal Stem Cell Function.
Tianyi Zhu, Ruohua Chen, +7 authors, Zeng Li, Jun Tian, Changwen Deng, Xingxing Zhang, Koudong Zhang, Linrong Tong, Yizhi Yu, Chong Bai. less
Int J Med Sci, 2016 Mar 05; 13(2). PMID: 26941575 Free PMC article.
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Glutamate dependent NMDA receptor 2D is a novel angiogenic tumour endothelial marker in colorectal cancer.
Henry J M Ferguson, Joseph W Wragg, +3 authors, Stephen Ward, Victoria L Heath, Tariq Ismail, Roy Bicknell. less
Oncotarget, 2016 Mar 05; 7(15). PMID: 26943033 Free PMC article.
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TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity.
Stian Foss, Ruth E Watkinson, +8 authors, Algirdas Grevys, Martin B McAdam, Malin Bern, Lene Stokken Høydahl, Bjørn Dalhus, Terje E Michaelsen, Inger Sandlie, Leo C James, Jan Terje Andersen. less
J Immunol, 2016 Mar 11; 196(8). PMID: 26962230 Free PMC article.
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Involvement of B cells in non-infectious uveitis.
Justine R Smith, Andrew J Stempel, Arpita Bharadwaj, Binoy Appukuttan.
Clin Transl Immunology, 2016 Mar 11; 5(2). PMID: 26962453 Free PMC article.
Review.
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Molecular modeling of antibodies for the treatment of TNFα-related immunological diseases.
Ciro Leonardo Pierri, Fabrizio Bossis, +4 authors, Giuseppe Punzi, Anna De Grassi, Michela Cetrone, Giovanni Parisi, Domenico Tricarico. less
Pharmacol Res Perspect, 2016 Mar 16; 4(1). PMID: 26977294 Free PMC article.
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Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Andrew Leaver-Fay, Karen J Froning, +10 authors, Shane Atwell, Hector Aldaz, Anna Pustilnik, Frances Lu, Flora Huang, Richard Yuan, Saleema Hassanali, Aaron K Chamberlain, Jonathan R Fitchett, Stephen J Demarest, Brian Kuhlman. less
Structure, 2016 Mar 22; 24(4). PMID: 26996964 Free PMC article.
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Rapid and Long-Term Immunity Elicited by DNA-Encoded Antibody Prophylaxis and DNA Vaccination Against Chikungunya Virus.
Karuppiah Muthumani, Peter Block, +15 authors, Seleeke Flingai, Nagarajan Muruganantham, Itta Krishna Chaaithanya, Colleen Tingey, Megan Wise, Emma L Reuschel, Christopher Chung, Abirami Muthumani, Gopalsamy Sarangan, Padma Srikanth, Amir S Khan, Paluru Vijayachari, Niranjan Y Sardesai, J Joseph Kim, Kenneth E Ugen, David B Weiner. less
J Infect Dis, 2016 Mar 24; 214(3). PMID: 27001960 Free PMC article.
Highly Cited.
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New Insights into Molecular Mechanisms of Immune Complex-Induced Injury in Lung.
Peter A Ward, Fatemeh Fattahi, Markus Bosmann.
Front Immunol, 2016 Mar 26; 7. PMID: 27014266 Free PMC article.
Review.
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DC-STAMP: A Key Regulator in Osteoclast Differentiation.
Ya-Hui Chiu, Christopher T Ritchlin.
J Cell Physiol, 2016 Mar 29; 231(11). PMID: 27018136 Free PMC article.
Review.
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Signals and Receptors.
Carl-Henrik Heldin, Benson Lu, Ron Evans, J Silvio Gutkind.
Cold Spring Harb Perspect Biol, 2016 Apr 03; 8(4). PMID: 27037414 Free PMC article.
Review.
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The FcγR/IgG Interaction as Target for the Treatment of Autoimmune Diseases.
Peter Sondermann.
J Clin Immunol, 2016 Apr 04; 36 Suppl 1. PMID: 27039179
Review.
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FCGR3A-V158F polymorphism is a disease-specific pharmacogenetic marker for the treatment of psoriasis with Fc-containing TNFα inhibitors.
E Mendrinou, A Patsatsi, +9 authors, E Zafiriou, D Papadopoulou, L Aggelou, C Sarri, Z Mamuris, A Kyriakou, D Sotiriadis, A Roussaki-Schulze, T Sarafidou, Y Vasilopoulos. less
Pharmacogenomics J, 2016 Apr 06; 17(3). PMID: 27044681
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Resistance is futile: Targeting the inhibitory FcγRIIB (CD32B) to maximize immunotherapy.
Ali Roghanian, Mark S Cragg, Björn Frendéus.
Oncoimmunology, 2016 Apr 09; 5(2). PMID: 27057434 Free PMC article.
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FCGR3A and FCGR3B copy number variations are risk factors for sarcoidosis.
Jianming Wu, Yunfang Li, +3 authors, Weihua Guan, Kevin Viken, David M Perlman, Maneesh Bhargava. less
Hum Genet, 2016 Apr 10; 135(7). PMID: 27059607
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Associations between PTPRC rs10919563 A/G and FCGR2A R131H polymorphisms and responsiveness to TNF blockers in rheumatoid arthritis: a meta-analysis.
Young Ho Lee, Sang-Cheol Bae.
Rheumatol Int, 2016 Apr 15; 36(6). PMID: 27074847
Review.
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Effect of CD16a, the surface receptor of Kupffer cells, on the growth of hepatocellular carcinoma cells.
Xiu-Yun Li, Lun Wu, +5 authors, Sheng-Wei Li, Wen-Bo Zhou, Meng-Yuan Wang, Guo-Qing Zuo, Chang-An Liu, Xiong Ding. less
Int J Mol Med, 2016 Apr 16; 37(6). PMID: 27082928 Free PMC article.
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Immune Complex-Induced, Nitric Oxide-Mediated Vascular Endothelial Cell Death by Phagocytes Is Prevented with Decoy FcγReceptors.
Ramanjaneya V R Mula, Deepa Machiah, +5 authors, Lauren Holland, Xinyu Wang, Harish Parihar, Avadhesh C Sharma, Periasamy Selvaraj, Rangaiah Shashidharamurthy. less
PLoS One, 2016 Apr 23; 11(4). PMID: 27101012 Free PMC article.
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Comparison of Antibody-Dependent Cell-Mediated Cytotoxicity and Virus Neutralization by HIV-1 Env-Specific Monoclonal Antibodies.
Benjamin von Bredow, Juan F Arias, +6 authors, Lisa N Heyer, Brian Moldt, Khoa Le, James E Robinson, Susan Zolla-Pazner, Dennis R Burton, David T Evans. less
J Virol, 2016 Apr 29; 90(13). PMID: 27122574 Free PMC article.
Highly Cited.
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Expression Profile of Human Fc Receptors in Mucosal Tissue: Implications for Antibody-Dependent Cellular Effector Functions Targeting HIV-1 Transmission.
Hannah M Cheeseman, Ann M Carias, +5 authors, Abbey B Evans, Natalia J Olejniczak, Paul Ziprin, Deborah F L King, Thomas J Hope, Robin J Shattock. less
PLoS One, 2016 May 11; 11(5). PMID: 27164006 Free PMC article.
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Generation of BiKEs and TriKEs to Improve NK Cell-Mediated Targeting of Tumor Cells.
Martin Felices, Todd R Lenvik, +2 authors, Zachary B Davis, Jeffrey S Miller, Daniel A Vallera. less
Methods Mol Biol, 2016 May 15; 1441. PMID: 27177679 Free PMC article.
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Antitumor Efficacy of Anti-GD2 IgG1 Is Enhanced by Fc Glyco-Engineering.
Hong Xu, Hongfen Guo, Irene Y Cheung, Nai-Kong V Cheung.
Cancer Immunol Res, 2016 May 20; 4(7). PMID: 27197064 Free PMC article.
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Sialylated intravenous immunoglobulin suppress anti-ganglioside antibody mediated nerve injury.
Gang Zhang, Cynthia A Massaad, +4 authors, Tong Gao, Laila Pillai, Natalia Bogdanova, Sameera Ghauri, Kazim A Sheikh. less
Exp Neurol, 2016 May 22; 282. PMID: 27208700 Free PMC article.
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Characterization of NF-κB Reporter U937 Cells and Their Application for the Detection of Inflammatory Immune-Complexes.
Csilla Kecse-Nagy, Zoltán Szittner, +6 authors, Krisztián Papp, Zoltán Hegyi, Paolo Rovero, Paola Migliorini, Veronika Lóránd, László Homolya, József Prechl. less
PLoS One, 2016 May 28; 11(5). PMID: 27232500 Free PMC article.
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Aspergillus Cell Wall Chitin Induces Anti- and Proinflammatory Cytokines in Human PBMCs via the Fc-γ Receptor/Syk/PI3K Pathway.
K L Becker, V Aimanianda, +8 authors, X Wang, M S Gresnigt, A Ammerdorffer, C W Jacobs, R P Gazendam, L A B Joosten, M G Netea, J P Latgé, F L van de Veerdonk. less
mBio, 2016 Jun 02; 7(3). PMID: 27247234 Free PMC article.
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Therapeutic implications of autoantibodies in rheumatoid arthritis.
Daniel Aletaha, Stephan Blüml.
RMD Open, 2016 Jun 03; 2(1). PMID: 27252890 Free PMC article.
Review.
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Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement.
Rony Dahan, Bryan C Barnhart, +3 authors, Fubin Li, Aaron P Yamniuk, Alan J Korman, Jeffrey V Ravetch. less
Cancer Cell, 2016 Jun 07; 29(6). PMID: 27265505 Free PMC article.
Highly Cited.
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Association of FCGR2A rs1801274 polymorphism with susceptibility to autoimmune diseases: A meta-analysis.
Chang'e Zhang, Wenju Wang, +2 authors, Hong'e Zhang, Lulu Wei, Shuping Guo. less
Oncotarget, 2016 Oct 26; 7(26). PMID: 27270653 Free PMC article.
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Perinatal HIV-1 transmission: Fc gamma receptor variability associates with maternal infectiousness and infant susceptibility.
Ria Lassaunière, Alfred Musekiwa, +2 authors, Glenda E Gray, Louise Kuhn, Caroline T Tiemessen. less
Retrovirology, 2016 Jun 12; 13(1). PMID: 27287460 Free PMC article.
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Human CD4(+) T-Cells: A Role for Low-Affinity Fc Receptors.
Anil K Chauhan.
Front Immunol, 2016 Jun 18; 7. PMID: 27313579 Free PMC article.
Review.
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CD16 and CD32 Gene Polymorphisms May Contribute to Risk of Idiopathic Thrombocytopenic Purpura.
Jiannan Xu, Liyun Zhao, +2 authors, Yan Zhang, Qingxu Guo, Hui Chen. less
Med Sci Monit, 2016 Jun 19; 22. PMID: 27315784 Free PMC article.
Review.
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Enhancement of Immune Effector Functions by Modulating IgG's Intrinsic Affinity for Target Antigen.
Yariv Mazor, Chunning Yang, +4 authors, M Jack Borrok, Joanne Ayriss, Karen Aherne, Herren Wu, William F Dall'Acqua. less
PLoS One, 2016 Jun 21; 11(6). PMID: 27322177 Free PMC article.
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FcγR mediates TLR2- and Syk-dependent NLRP3 inflammasome activation by inactivated Francisella tularensis LVS immune complexes.
Ellen B Duffy, Sivakumar Periasamy, +2 authors, Danielle Hunt, James R Drake, Jonathan A Harton. less
J Leukoc Biol, 2016 Jul 02; 100(6). PMID: 27365531 Free PMC article.
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Third-stage Gnathostoma spinigerum larva excretory secretory antigens modulate function of Fc gamma receptor I-mediated monocytes in peripheral blood mononuclear cell culture.
Surachet Benjathummarak, Ratchanok Kumsiri, +4 authors, Supaporn Nuamtanong, Thareerat Kalambaheti, Jitra Waikagul, Nareerat Viseshakul, Yaowapa Maneerat. less
Trop Med Health, 2016 Jul 12; 44. PMID: 27398064 Free PMC article.
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An Fc-optimized CD133 antibody for induction of NK cell reactivity against myeloid leukemia.
S P Koerner, M C André, +8 authors, J S Leibold, P C Kousis, A Kübler, M Pal, S P Haen, H-J Bühring, L Grosse-Hovest, G Jung, H R Salih. less
Leukemia, 2016 Jul 21; 31(2). PMID: 27435001
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Modulation of Stat-1 in Human Macrophages Infected with Different Species of Intracellular Pathogenic Bacteria.
Giuditta Fiorella Schiavano, Sabrina Dominici, +3 authors, Laura Rinaldi, Alfonsina Mariarosaria Cangiano, Giorgio Brandi, Mauro Magnani. less
J Immunol Res, 2016 Jul 21; 2016. PMID: 27437406 Free PMC article.
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Enhancement of antibody-dependent cell mediated cytotoxicity: a new era in cancer treatment.
Narendiran Rajasekaran, Cariad Chester, +2 authors, Atsushi Yonezawa, Xing Zhao, Holbrook E Kohrt. less
Immunotargets Ther, 2015 Jan 01; 4. PMID: 27471715 Free PMC article.
Review.
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Immune Monitoring of Trans-endothelial Transport by Kidney-Resident Macrophages.
Efstathios G Stamatiades, Marie-Eve Tremblay, +11 authors, Mathieu Bohm, Lucile Crozet, Kanchan Bisht, Daniela Kao, Carolina Coelho, Xiying Fan, William T Yewdell, Anne Davidson, Peter S Heeger, Sandra Diebold, Falk Nimmerjahn, Frederic Geissmann. less
Cell, 2016 Aug 02; 166(4). PMID: 27477514 Free PMC article.
Highly Cited.
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Characterization of low affinity Fcγ receptor biotinylation under controlled reaction conditions by mass spectrometry and ligand binding analysis.
Karin P M Geuijen, David F Egging, +3 authors, Stefanie Bartels, Jan Schouten, Richard B Schasfoort, Michel H Eppink. less
Protein Sci, 2016 Aug 02; 25(10). PMID: 27479529 Free PMC article.
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Broadly Neutralizing Activity of Zika Virus-Immune Sera Identifies a Single Viral Serotype.
Kimberly A Dowd, Christina R DeMaso, +10 authors, Rebecca S Pelc, Scott D Speer, Alexander R Y Smith, Leslie Goo, Derek J Platt, John R Mascola, Barney S Graham, Mark J Mulligan, Michael S Diamond, Julie E Ledgerwood, Theodore C Pierson. less
Cell Rep, 2016 Aug 03; 16(6). PMID: 27481466 Free PMC article.
Highly Cited.
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Converting monoclonal antibody-based immunotherapies from passive to active: bringing immune complexes into play.
Jennifer Lambour, Mar Naranjo-Gomez, Marc Piechaczyk, Mireia Pelegrin.
Emerg Microbes Infect, 2016 Aug 18; 5(8). PMID: 27530750 Free PMC article.
Review.
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Malignant Mesothelioma Effusions Are Infiltrated by CD3+ T Cells Highly Expressing PD-L1 and the PD-L1+ Tumor Cells within These Effusions Are Susceptible to ADCC by the Anti-PD-L1 Antibody Avelumab.
Swati Khanna, Anish Thomas, +8 authors, Daniel Abate-Daga, Jingli Zhang, Betsy Morrow, Seth M Steinberg, Augusto Orlandi, Patrizia Ferroni, Jeffrey Schlom, Fiorella Guadagni, Raffit Hassan. less
J Thorac Oncol, 2016 Oct 25; 11(11). PMID: 27544053 Free PMC article.
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Immunoregulatory functions of immune complexes in vaccine and therapy.
Yu-Mei Wen, Libing Mu, Yan Shi.
EMBO Mol Med, 2016 Aug 31; 8(10). PMID: 27572622 Free PMC article.
Review.
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Investigation of the Immunomodulatory effect of Berberis vulgaris on core-pulsed dendritic cell vaccine.
Doaa A Ghareeb, Eiman H Elwakeel, +2 authors, Rowaida Khalil, Mina S Aziz, Maha A El Demellawy. less
BMC Complement Altern Med, 2016 Sep 01; 16(1). PMID: 27577059 Free PMC article.
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Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses.
Matthew Zirui Tay, Pinghuang Liu, +12 authors, LaTonya D Williams, Michael D McRaven, Sheetal Sawant, Thaddeus C Gurley, Thomas T Xu, S Moses Dennison, Hua-Xin Liao, Agnès-Laurence Chenine, S Munir Alam, M Anthony Moody, Thomas J Hope, Barton F Haynes, Georgia D Tomaras. less
PLoS Pathog, 2016 Sep 01; 12(8). PMID: 27579713 Free PMC article.
Highly Cited.
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Effects of anchor structure and glycosylation of Fcγ receptor III on ligand binding affinity.
Ning Jiang, Wei Chen, +4 authors, Prithiviraj Jothikumar, Jaina M Patel, Rangaiah Shashidharamurthy, Periasamy Selvaraj, Cheng Zhu. less
Mol Biol Cell, 2016 Nov 05; 27(22). PMID: 27582391 Free PMC article.
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Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology.
Mark J Selby, John J Engelhardt, +11 authors, Robert J Johnston, Li-Sheng Lu, Minhua Han, Kent Thudium, Dapeng Yao, Michael Quigley, Jose Valle, Changyu Wang, Bing Chen, Pina M Cardarelli, Diann Blanset, Alan J Korman. less
PLoS One, 2016 Sep 10; 11(9). PMID: 27610613 Free PMC article.
Highly Cited.
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Effects of allergic diseases and age on the composition of serum IgG glycome in children.
Marija Pezer, Jerko Stambuk, +13 authors, Marija Perica, Genadij Razdorov, Ivana Banic, Frano Vuckovic, Adrijana Miletic Gospic, Ivo Ugrina, Ana Vecenaj, Maja Pucic Bakovic, Sandra Bulat Lokas, Jelena Zivkovic, Davor Plavec, Graham Devereux, Mirjana Turkalj, Gordan Lauc. less
Sci Rep, 2016 Sep 13; 6. PMID: 27616597 Free PMC article.
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Active but not inactive granulomatosis with polyangiitis is associated with decreased and phenotypically and functionally altered CD56(dim) natural killer cells.
Wolfgang Merkt, Maren Claus, +4 authors, Norbert Blank, Michael Hundemer, Adelheid Cerwenka, Hanns-Martin Lorenz, Carsten Watzl. less
Arthritis Res Ther, 2016 Sep 15; 18(1). PMID: 27624647 Free PMC article.
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Rituximab induces phenotypical and functional changes of NK cells in a non-malignant experimental setting.
Wolfgang Merkt, Hanns-Martin Lorenz, Carsten Watzl.
Arthritis Res Ther, 2016 Sep 16; 18(1). PMID: 27629249 Free PMC article.
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Regulation of FcRγ function by site-specific serine phosphorylation.
Spandan Shah, Andrew W Gibson, +5 authors, Chuanyi Ji, Eric Darrington, James Mobley, Kyoko Kojima, Jeffrey C Edberg, Robert P Kimberly. less
J Leukoc Biol, 2016 Sep 16; 101(2). PMID: 27630214 Free PMC article.
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Myeloid-derived suppressor cells in murine AIDS inhibit B-cell responses in part via soluble mediators including reactive oxygen and nitrogen species, and TGF-β.
Jessica L Rastad, William R Green.
Virology, 2016 Sep 16; 499. PMID: 27632561 Free PMC article.
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A Functional Role for Antibodies in Tuberculosis.
Lenette L Lu, Amy W Chung, +22 authors, Tracy R Rosebrock, Musie Ghebremichael, Wen Han Yu, Patricia S Grace, Matthew K Schoen, Fikadu Tafesse, Constance Martin, Vivian Leung, Alison E Mahan, Magdalena Sips, Manu P Kumar, Jacquelynne Tedesco, Hannah Robinson, Elizabeth Tkachenko, Monia Draghi, Katherine J Freedberg, Hendrik Streeck, Todd J Suscovich, Douglas A Lauffenburger, Blanca I Restrepo, Cheryl Day, Sarah M Fortune, Galit Alter. less
Cell, 2016 Sep 27; 167(2). PMID: 27667685 Free PMC article.
Highly Cited.
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Humoral Immunity Provides Resident Intestinal Eosinophils Access to Luminal Antigen via Eosinophil-Expressed Low-Affinity Fcγ Receptors.
Kalmia M Smith, Raiann S Rahman, Lisa A Spencer.
J Immunol, 2016 Sep 30; 197(9). PMID: 27683752 Free PMC article.
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Antigen modulation as a potential mechanism of anti-KEL immunoprophylaxis in mice.
Jingchun Liu, Manjula Santhanakrishnan, +7 authors, Prabitha Natarajan, David R Gibb, Stephanie C Eisenbarth, Christopher A Tormey, Alexa J Siddon, Sean R Stowell, Donald R Branch, Jeanne E Hendrickson. less
Blood, 2016 Oct 01; 128(26). PMID: 27688803 Free PMC article.
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Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus.
Wenqian He, Gene S Tan, +8 authors, Caitlin E Mullarkey, Amanda J Lee, Mannie Man Wai Lam, Florian Krammer, Carole Henry, Patrick C Wilson, Ali A Ashkar, Peter Palese, Matthew S Miller. less
Proc Natl Acad Sci U S A, 2016 Oct 30; 113(42). PMID: 27698132 Free PMC article.
Highly Cited.
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Impact of Glycosylation on Effector Functions of Therapeutic IgG.
Riad Abès, Jean-Luc Teillaud.
Pharmaceuticals (Basel), 2010 Jan 12; 3(1). PMID: 27713246 Free PMC article.
Review.
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Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) Regulates Osteoclast Differentiation via the Ca2+ /NFATc1 Axis.
Ya-Hui Chiu, Edward Schwarz, +12 authors, Dongge Li, Yuexin Xu, Tzong-Ren Sheu, Jinbo Li, Karen L de Mesy Bentley, Changyong Feng, Baoli Wang, Jhih-Cheng Wang, Liz Albertorio-Saez, Ronald Wood, Minsoo Kim, Wensheng Wang, Christopher T Ritchlin. less
J Cell Physiol, 2016 Oct 11; 232(9). PMID: 27723141 Free PMC article.
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Leukocyte immunoglobulin-like receptor B4 regulates key signalling molecules involved in FcγRI-mediated clathrin-dependent endocytosis and phagocytosis.
Mijeong Park, Mark J Raftery, +3 authors, Paul S Thomas, Carolyn L Geczy, Katherine Bryant, Nicodemus Tedla. less
Sci Rep, 2016 Oct 12; 6. PMID: 27725776 Free PMC article.
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Soluble fibrinogen like protein 2 (sFGL2), the novel effector molecule for immunoregulation.
Xin-Guang Liu, Yu Liu, Feng Chen.
Oncotarget, 2016 Oct 13; 8(2). PMID: 27732962 Free PMC article.
Review.
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FCGR Polymorphisms Influence Response to IL2 in Metastatic Renal Cell Carcinoma.
Amy K Erbe, Wei Wang, +15 authors, Jacob Goldberg, Mikayla Gallenberger, KyungMann Kim, Lakeesha Carmichael, Dustin Hess, Eneida A Mendonca, Yiqiang Song, Jacquelyn A Hank, Su-Chun Cheng, Sabina Signoretti, Michael Atkins, Alexander Carlson, James W Mier, David J Panka, David F McDermott, Paul M Sondel. less
Clin Cancer Res, 2016 Nov 01; 23(9). PMID: 27742794 Free PMC article.
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FcμR in human B cell subsets in primary selective IgM deficiency, and regulation of FcμR and production of natural IgM antibodies by IGIV.
Sudhir Gupta, Sudhanshu Agrawal, Sastry Gollapudi, Hiromi Kubagawa.
Hum Immunol, 2016 Oct 19; 77(12). PMID: 27751883 Free PMC article.
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The contribution of the programmed cell death machinery in innate immune cells to lupus nephritis.
FuNien Tsai, Harris Perlman, Carla M Cuda.
Clin Immunol, 2016 Nov 05; 185. PMID: 27780774 Free PMC article.
Review.
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Immunoglobulin Glycosylation Effects in Allergy and Immunity.
Alexandra Epp, Kathryn C Sullivan, Andrew B Herr, Richard T Strait.
Curr Allergy Asthma Rep, 2016 Nov 01; 16(11). PMID: 27796794
Review.
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CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP.
Chizuru Akatsu, Kenro Shinagawa, +8 authors, Nobutaka Numoto, Zhihong Liu, Ayse Konuskan Ucar, Mohammad Aslam, Shirly Phoon, Takahiro Adachi, Koji Furukawa, Nobutoshi Ito, Takeshi Tsubata. less
J Exp Med, 2016 Nov 05; 213(12). PMID: 27810925 Free PMC article.
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Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation.
Anissa S H Chan, Adria Bykowski Jonas, +13 authors, Xiaohong Qiu, Nadine R Ottoson, Richard M Walsh, Keith B Gorden, Ben Harrison, Peter J Maimonis, Steven M Leonardo, Kathleen E Ertelt, Michael E Danielson, Kyle S Michel, Mariana Nelson, Jeremy R Graff, Myra L Patchen, Nandita Bose. less
PLoS One, 2016 Nov 05; 11(11). PMID: 27812183 Free PMC article.
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Akt and SHP-1 are DC-intrinsic checkpoints for tumor immunity.
Yaron Carmi, Tyler R Prestwood, +10 authors, Matthew H Spitzer, Ian L Linde, Jonathan Chabon, Nathan E Reticker-Flynn, Nupur Bhattacharya, Hong Zhang, Xiangyue Zhang, Pamela A Basto, Bryan M Burt, Michael N Alonso, Edgar G Engleman. less
JCI Insight, 2016 Nov 05; 1(18). PMID: 27812544 Free PMC article.
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CD19-specific triplebody SPM-1 engages NK and γδ T cells for rapid and efficient lysis of malignant B-lymphoid cells.
Christian B Schiller, Todd A Braciak, +12 authors, Nadja C Fenn, Ursula J E Seidel, Claudia C Roskopf, Sarah Wildenhain, Annemarie Honegger, Ingo A Schubert, Alexandra Schele, Kerstin Lämmermann, Georg H Fey, Uwe Jacob, Peter Lang, Karl-Peter Hopfner, Fuat S Oduncu. less
Oncotarget, 2016 Nov 09; 7(50). PMID: 27825135 Free PMC article.
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FcγRIIb-SHIP2 axis links Aβ to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model.
Tae-In Kam, Hyejin Park, +5 authors, Youngdae Gwon, Sungmin Song, Seo-Hyun Kim, Seo Won Moon, Dong-Gyu Jo, Yong-Keun Jung. less
Elife, 2016 Nov 12; 5. PMID: 27834631 Free PMC article.
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Chicken IgY Fc Linked to Bordetella avium ompA and Taishan Pinus massoniana Pollen Polysaccharide Adjuvant Enhances Macrophage Function and Specific Immune Responses.
Wenwen Dong, Hao Zhang, +8 authors, He Huang, Jianbo Zhou, Liping Hu, Ailing Lian, Lijun Zhu, Ningning Ma, Pingping Yang, Kai Wei, Ruiliang Zhu. less
Front Microbiol, 2016 Nov 17; 7. PMID: 27847501 Free PMC article.
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Dendritic cell-elicited B-cell activation fosters immune privilege via IL-10 signals in hepatocellular carcinoma.
Fang-Zhu Ouyang, Rui-Qi Wu, +7 authors, Yuan Wei, Rui-Xian Liu, Dong Yang, Xiao Xiao, Limin Zheng, Bo Li, Xiang-Ming Lao, Dong-Ming Kuang. less
Nat Commun, 2016 Nov 18; 7. PMID: 27853178 Free PMC article.
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A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells.
E J Cheadle, G Lipowska-Bhalla, +4 authors, S J Dovedi, E Fagnano, C Klein, J Honeychurch, T M Illidge. less
Leukemia, 2016 Nov 29; 31(7). PMID: 27890931 Free PMC article.
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Fc gamma receptors: glycobiology and therapeutic prospects.
Jerrard M Hayes, Mark R Wormald, Pauline M Rudd, Gavin P Davey.
J Inflamm Res, 2016 Nov 30; 9. PMID: 27895507 Free PMC article.
Review.
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Sequence diversity of dengue virus type 2 in brain and thymus of infected interferon receptor ko mice: implications for dengue virulence.
Priya Dhole, Emi E Nakayama, +4 authors, Akatsuki Saito, Kriengsak Limkittikul, Supranee Phanthanawiboon, Tatsuo Shioda, Takeshi Kurosu. less
Virol J, 2016 Dec 03; 13(1). PMID: 27903277 Free PMC article.
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Structural Insights into Reovirus σ1 Interactions with Two Neutralizing Antibodies.
Melanie H Dietrich, Kristen M Ogden, +7 authors, Sarah P Katen, Kerstin Reiss, Danica M Sutherland, Robert H Carnahan, Matthew Goff, Tracy Cooper, Terence S Dermody, Thilo Stehle. less
J Virol, 2016 Dec 09; 91(4). PMID: 27928010 Free PMC article.
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Understanding the Genomic Structure of Copy-Number Variation of the Low-Affinity Fcγ Receptor Region Allows Confirmation of the Association of FCGR3B Deletion with Rheumatoid Arthritis.
Raheleh Rahbari, Luciana W Zuccherato, +6 authors, German Tischler, Belinda Chihota, Hasret Ozturk, Sara Saleem, Eduardo Tarazona-Santos, Lee R Machado, Edward J Hollox. less
Hum Mutat, 2016 Dec 21; 38(4). PMID: 27995740 Free PMC article.
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TIARP attenuates autoantibody-mediated arthritis via the suppression of neutrophil migration by reducing CXCL2/CXCR2 and IL-6 expression.
Asuka Inoue, Isao Matsumoto, +9 authors, Yuki Tanaka, Naoto Umeda, Chinatsu Takai, Hoshimi Kawaguchi, Hiroshi Ebe, Hiroto Yoshida, Yoshihiro Matsumoto, Seiji Segawa, Satoru Takahashi, Takayuki Sumida. less
Sci Rep, 2016 Dec 21; 6. PMID: 27995997 Free PMC article.
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Cell-Based Screen Identifies Human Interferon-Stimulated Regulators of Listeria monocytogenes Infection.
Sofya S Perelman, Michael E Abrams, +5 authors, Jennifer L Eitson, Didi Chen, Alyssa Jimenez, Marcel Mettlen, John W Schoggins, Neal M Alto. less
PLoS Pathog, 2016 Dec 22; 12(12). PMID: 28002492 Free PMC article.
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Fcγ-receptor IIa-mediated Src Signaling Pathway Is Essential for the Antibody-Dependent Enhancement of Ebola Virus Infection.
Wakako Furuyama, Andrea Marzi, +9 authors, Aaron B Carmody, Junki Maruyama, Makoto Kuroda, Hiroko Miyamoto, Asuka Nanbo, Rashid Manzoor, Reiko Yoshida, Manabu Igarashi, Heinz Feldmann, Ayato Takada. less
PLoS Pathog, 2016 Dec 31; 12(12). PMID: 28036370 Free PMC article.
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The Impact of HLA Class I-Specific Killer Cell Immunoglobulin-Like Receptors on Antibody-Dependent Natural Killer Cell-Mediated Cytotoxicity and Organ Allograft Rejection.
Raja Rajalingam.
Front Immunol, 2017 Jan 10; 7. PMID: 28066408 Free PMC article.
Review.
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Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice.
Megan Lo, Hok Seon Kim, +14 authors, Raymond K Tong, Travis W Bainbridge, Jean-Michel Vernes, Yin Zhang, Yuwen Linda Lin, Shan Chung, Mark S Dennis, Y Joy Yu Zuchero, Ryan J Watts, Jessica A Couch, Y Gloria Meng, Jasvinder K Atwal, Randall J Brezski, Christoph Spiess, James A Ernst. less
J Biol Chem, 2017 Jan 13; 292(9). PMID: 28077575 Free PMC article.
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Comparison of Multiple Methods for Determination of FCGR3A/B Genomic Copy Numbers in HapMap Asian Populations with Two Public Databases.
Yuan-Yuan Qi, Xu-Jie Zhou, +3 authors, Ding-Fang Bu, Ping Hou, Ji-Cheng Lv, Hong Zhang. less
Front Genet, 2017 Jan 14; 7. PMID: 28083015 Free PMC article.
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FcRγ-dependent immune activation initiates astrogliosis during the asymptomatic phase of Sandhoff disease model mice.
Yasuhiro Ogawa, Takafumi Sano, +11 authors, Masahiro Irisa, Takashi Kodama, Takahiro Saito, Eiri Furusawa, Katsutoshi Kaizu, Yusuke Yanagi, Takahiro Tsukimura, Tadayasu Togawa, Shoji Yamanaka, Kohji Itoh, Hitoshi Sakuraba, Kazuhiko Oishi. less
Sci Rep, 2017 Jan 14; 7. PMID: 28084424 Free PMC article.
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The Role and Function of Fcγ Receptors on Myeloid Cells.
Stylianos Bournazos, Taia T Wang, Jeffrey V Ravetch.
Microbiol Spectr, 2017 Jan 15; 4(6). PMID: 28087938 Free PMC article.
Review.
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Targeted Fcγ Receptor (FcγR)-mediated Clearance by a Biparatopic Bispecific Antibody.
Srinath Kasturirangan, G Jonah Rainey, +10 authors, Linda Xu, Xinwei Wang, Alyse Portnoff, Tracy Chen, Christine Fazenbaker, Helen Zhong, Jared Bee, Zhutian Zeng, Craig Jenne, Herren Wu, Changshou Gao. less
J Biol Chem, 2017 Jan 20; 292(10). PMID: 28100773 Free PMC article.
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Enhancement of antibody functions through Fc multiplications.
Qun Wang, Yan Chen, +11 authors, Mark Pelletier, Romana Cvitkovic, Jessica Bonnell, Chien-Ying Chang, Adem C Koksal, Ellen O'Connor, Xizhe Gao, Xiang-Qing Yu, Herren Wu, C Kendall Stover, William F Dall'Acqua, Xiaodong Xiao. less
MAbs, 2017 Jan 20; 9(3). PMID: 28102754 Free PMC article.
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Comparative transcriptomics of elasmobranchs and teleosts highlight important processes in adaptive immunity and regional endothermy.
Nicholas J Marra, Vincent P Richards, +4 authors, Angela Early, Steve M Bogdanowicz, Paulina D Pavinski Bitar, Michael J Stanhope, Mahmood S Shivji. less
BMC Genomics, 2017 Jan 31; 18(1). PMID: 28132643 Free PMC article.
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Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies.
Elie Dheilly, Valéry Moine, +12 authors, Lucile Broyer, Susana Salgado-Pires, Zoë Johnson, Anne Papaioannou, Laura Cons, Sébastien Calloud, Stefano Majocchi, Robert Nelson, François Rousseau, Walter Ferlin, Marie Kosco-Vilbois, Nicolas Fischer, Krzysztof Masternak. less
Mol Ther, 2017 Feb 06; 25(2). PMID: 28153099 Free PMC article.
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Modulation of Microglial Cell Fcγ Receptor Expression Following Viral Brain Infection.
Priyanka Chauhan, Shuxian Hu, +2 authors, Wen S Sheng, Sujata Prasad, James R Lokensgard. less
Sci Rep, 2017 Feb 07; 7. PMID: 28165503 Free PMC article.
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Spontaneous germinal centers and autoimmunity.
Phillip P Domeier, Stephanie L Schell, Ziaur S M Rahman.
Autoimmunity, 2017 Feb 09; 50(1). PMID: 28166685 Free PMC article.
Review.
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B cells interactions in lipid immune responses: implications in atherosclerotic disease.
Laura C Echeverri Tirado, Lina M Yassin.
Lipids Health Dis, 2017 Feb 09; 16(1). PMID: 28166809 Free PMC article.
Review.
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Therapeutic antibody targeting of indoleamine-2,3-dioxygenase (IDO2) inhibits autoimmune arthritis.
Lauren M F Merlo, Samantha Grabler, +5 authors, James B DuHadaway, Elizabeth Pigott, Kaylend Manley, George C Prendergast, Lisa D Laury-Kleintop, Laura Mandik-Nayak. less
Clin Immunol, 2017 Feb 23; 179. PMID: 28223071 Free PMC article.
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Enhanced FCGR2A and FCGR3A signaling by HIV viremic controller IgG.
Raymond A Alvarez, Ana M Maestre, +11 authors, Kenneth Law, Natasha D Durham, Maria Ines Barria, Akiko Ishii-Watabe, Minoru Tada, Manav Kapoor, Mathew T Hotta, Gabriela Rodriguez-Caprio, Daniel S Fierer, Ana Fernandez-Sesma, Viviana Simon, Benjamin K Chen. less
JCI Insight, 2017 Feb 28; 2(4). PMID: 28239647 Free PMC article.
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Modulating IgG effector function by Fc glycan engineering.
Tiezheng Li, David J DiLillo, +3 authors, Stylianos Bournazos, John P Giddens, Jeffrey V Ravetch, Lai-Xi Wang. less
Proc Natl Acad Sci U S A, 2017 Mar 16; 114(13). PMID: 28289219 Free PMC article.
Highly Cited.
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Setting the target for pemphigus vulgaris therapy.
Christoph T Ellebrecht, Aimee S Payne.
JCI Insight, 2017 Mar 16; 2(5). PMID: 28289723 Free PMC article.
Review.
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Help is on the way: Monoclonal antibody therapy for multi-drug resistant bacteria.
Rachelle Babb, Liise-Anne Pirofski.
Virulence, 2017 Mar 18; 8(7). PMID: 28306387 Free PMC article.
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Antibody Functional Assays as Measures of Fc Receptor-Mediated Immunity to HIV - New Technologies and their Impact on the HIV Vaccine Field.
Bruce D Wines, Hugh Billings, +2 authors, Milla R Mclean, Stephen J Kent, P Mark Hogarth. less
Curr HIV Res, 2017 Mar 23; 15(3). PMID: 28322167 Free PMC article.
Review.
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Basal-like breast cancer: molecular profiles, clinical features and survival outcomes.
Heloisa H Milioli, Inna Tishchenko, +2 authors, Carlos Riveros, Regina Berretta, Pablo Moscato. less
BMC Med Genomics, 2017 Mar 30; 10(1). PMID: 28351365 Free PMC article.
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FcγRIIb expression in early stage chronic lymphocytic leukemia.
Rosa Bosch, Alba Mora, +19 authors, Eva Puy Vicente, Gerardo Ferrer, Sonia Jansà, Rajendra Damle, Sergey Gorlatov, Kanti Rai, Emili Montserrat, Josep Nomdedeu, Marta Pratcorona, Laura Blanco, Silvana Saavedra, Ana Garrido, Albert Esquirol, Irene Garcia, Miquel Granell, Rodrigo Martino, Julio Delgado, Jorge Sierra, Nicholas Chiorazzi, Carol Moreno. less
Leuk Lymphoma, 2017 Apr 05; 58(11). PMID: 28372509 Free PMC article.
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Fcγ Receptor Heterogeneity in Leukocyte Functional Responses.
Carlos Rosales.
Front Immunol, 2017 Apr 05; 8. PMID: 28373871 Free PMC article.
Highly Cited. Review.
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Two years' long-term follow up in chronic inflammatory demyelinating polyradiculoneuropathy: efficacy of intravenous immunoglobulin treatment.
Gisa Ellrichmann, Ralf Gold, +2 authors, Ilya Ayzenberg, Min-Suk Yoon, Christiane Schneider-Gold. less
Ther Adv Neurol Disord, 2017 Apr 07; 10(2). PMID: 28382108 Free PMC article.
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Trehalose dimycolate interferes with FcγR-mediated phagosome maturation through Mincle, SHP-1 and FcγRIIB signalling.
Emmanuel C Patin, Anna C Geffken, +6 authors, Sam Willcocks, Christoph Leschczyk, Albert Haas, Falk Nimmerjahn, Roland Lang, Theresa H Ward, Ulrich E Schaible. less
PLoS One, 2017 Apr 07; 12(4). PMID: 28384255 Free PMC article.
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DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo.
Christian H K Lehmann, Anna Baranska, +15 authors, Gordon F Heidkamp, Lukas Heger, Kirsten Neubert, Jennifer J Lühr, Alana Hoffmann, Katharina C Reimer, Christin Brückner, Simone Beck, Michaela Seeling, Melissa Kießling, Didier Soulat, Anne B Krug, Jeffrey V Ravetch, Jeanette H W Leusen, Falk Nimmerjahn, Diana Dudziak. less
J Exp Med, 2017 Apr 09; 214(5). PMID: 28389502 Free PMC article.
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Genetic architecture of gene expression underlying variation in host response to porcine reproductive and respiratory syndrome virus infection.
Arun Kommadath, Hua Bao, +12 authors, Igseo Choi, James M Reecy, James E Koltes, Elyn Fritz-Waters, Chris J Eisley, Jason R Grant, Robert R R Rowland, Christopher K Tuggle, Jack C M Dekkers, Joan K Lunney, Le Luo Guan, Paul Stothard, Graham S Plastow. less
Sci Rep, 2017 Apr 11; 7. PMID: 28393889 Free PMC article.
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Macrophage Polarization Modulates FcγR- and CD13-Mediated Phagocytosis and Reactive Oxygen Species Production, Independently of Receptor Membrane Expression.
Elizabeth Mendoza-Coronel, Enrique Ortega.
Front Immunol, 2017 Apr 12; 8. PMID: 28396660 Free PMC article.
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Targeting CD157 in AML using a novel, Fc-engineered antibody construct.
Christina Krupka, Felix S Lichtenegger, +14 authors, Thomas Köhnke, Jan Bögeholz, Veit Bücklein, Michael Roiss, Torben Altmann, To Uyen Do, Rachel Dusek, Keith Wilson, Arnima Bisht, Jon Terrett, Dee Aud, Esteban Pombo-Villar, Christian Rohlff, Wolfgang Hiddemann, Marion Subklewe. less
Oncotarget, 2017 Apr 19; 8(22). PMID: 28415689 Free PMC article.
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The lack of BTK does not impair monocytes and polymorphonuclear cells functions in X-linked agammaglobulinemia under treatment with intravenous immunoglobulin replacement.
Filomena Monica Cavaliere, Alessandro Prezzo, +2 authors, Caterina Bilotta, Metello Iacobini, Isabella Quinti. less
PLoS One, 2017 Apr 20; 12(4). PMID: 28422989 Free PMC article.
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Glycan Remodeling of Human Erythropoietin (EPO) Through Combined Mammalian Cell Engineering and Chemoenzymatic Transglycosylation.
Qiang Yang, Yanming An, +4 authors, Shilei Zhu, Roushu Zhang, Chun Mun Loke, John F Cipollo, Lai-Xi Wang. less
ACS Chem Biol, 2017 Apr 30; 12(6). PMID: 28452462 Free PMC article.
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Signature of the Sleeper Cell: A Biomarker of HIV Latency Revealed.
Satish K Pillai, Steven G Deeks.
Trends Immunol, 2017 May 18; 38(7). PMID: 28511815 Free PMC article.
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Favorable Response to Long-term Nucleos(t)ide Analogue Therapy in HBeAg-positive Patients with High Serum Fucosyl-Agalactosyl IgG.
Cheng-Hsun Ho, Hung-Wen Tsai, +8 authors, Chen-Yeh Lee, Li-Juan Huang, Rong-Nan Chien, I-Chin Wu, Yen-Cheng Chiu, Wen-Chun Liu, Pin-Nan Cheng, Ting-Tsung Chang, Shu-Hui Chen. less
Sci Rep, 2017 May 18; 7(1). PMID: 28512353 Free PMC article.
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T0001, a variant of TNFR2-Fc fusion protein, exhibits improved Fc effector functions through increased binding to membrane-bound TNFα.
Yijun Shen, Gang Li, +9 authors, Chunying Gu, Ben Chen, Aihua Chen, Hua Li, Bei Gao, Chencai Liang, Jingsong Wu, Tong Yang, Li Jin, Yong Su. less
PLoS One, 2017 May 26; 12(5). PMID: 28542350 Free PMC article.
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The Use of Xanthan Gum as Vaccine Adjuvant: An Evaluation of Immunostimulatory Potential in BALB/c Mice and Cytotoxicity In Vitro.
Rodrigo Andrade Schuch, Thaís Larré Oliveira, +6 authors, Thaís Farias Collares, Leonardo Garcia Monte, Guilherme Roig Inda, Odir Antonio Dellagostin, Claire Tondo Vendruscolo, Angelita da Silveira Moreira, Daiane Drawanz Hartwig. less
Biomed Res Int, 2017 May 31; 2017. PMID: 28555192 Free PMC article.
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Identification of Fc Gamma Receptor Glycoforms That Produce Differential Binding Kinetics for Rituximab.
Jerrard M Hayes, Asa Frostell, +8 authors, Robert Karlsson, Steffen Müller, Silvia Míllan Martín, Martin Pauers, Franziska Reuss, Eoin F Cosgrave, Cecilia Anneren, Gavin P Davey, Pauline M Rudd. less
Mol Cell Proteomics, 2017 Jun 04; 16(10). PMID: 28576848 Free PMC article.
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Drug discovery and therapeutic delivery for the treatment of B and T cell tumors.
Regan Stephenson, Ankur Singh.
Adv Drug Deliv Rev, 2017 Jun 20; 114. PMID: 28625826 Free PMC article.
Review.
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Selective activation of anti-CD73 mechanisms in control of primary tumors and metastases.
Dipti Vijayan, Deborah S Barkauskas, +7 authors, Kimberley Stannard, Erin Sult, Rebecca Buonpane, Kazuyoshi Takeda, Michele W L Teng, Kris Sachsenmeier, Carl Hay, Mark J Smyth. less
Oncoimmunology, 2017 Jun 24; 6(5). PMID: 28638737 Free PMC article.
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Pharmacokinetics of Monoclonal Antibodies.
Josiah T Ryman, Bernd Meibohm.
CPT Pharmacometrics Syst Pharmacol, 2017 Jun 28; 6(9). PMID: 28653357 Free PMC article.
Highly Cited. Review.
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Yeast lysates carrying the nucleoprotein from measles virus vaccine as a novel subunit vaccine platform to deliver Plasmodium circumsporozoite antigen.
Daria Jacob, Claude Ruffie, +5 authors, Chantal Combredet, Pauline Formaglio, Rogerio Amino, Robert Ménard, Frédéric Tangy, Monica Sala. less
Malar J, 2017 Jul 01; 16(1). PMID: 28662722 Free PMC article.
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A bioconjugate leveraging xenoreactive antibodies to alleviate cocaine-induced behavior.
NIcholas T Jacob, Kensaku Anraku, +5 authors, Atsushi Kimishima, Bin Zhou, Karen C Collins, Jonathan W Lockner, Beverley A Ellis, Kim D Janda. less
Chem Commun (Camb), 2017 Jul 06; 53(58). PMID: 28677711 Free PMC article.
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Engineering Aglycosylated IgG Variants with Wild-Type or Improved Binding Affinity to Human Fc Gamma RIIA and Fc Gamma RIIIAs.
Tiffany F Chen, Stephen L Sazinsky, +8 authors, Damian Houde, David J DiLillo, Julie Bird, Kevin K Li, George T Cheng, Huawei Qiu, John R Engen, Jeffrey V Ravetch, K Dane Wittrup. less
J Mol Biol, 2017 Jul 12; 429(16). PMID: 28694069 Free PMC article.
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Regulation of Subunit-Specific Germinal Center B Cell Responses to the HIV-1 Envelope Glycoproteins by Antibody-Mediated Feedback.
Mattias N E Forsell, Linda Kvastad, +2 authors, Saikiran K Sedimbi, John Andersson, Mikael C I Karlsson. less
Front Immunol, 2017 Jul 18; 8. PMID: 28713371 Free PMC article.
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Neurofilament light as an immune target for pathogenic antibodies.
Fabiola Puentes, Baukje J van der Star, +10 authors, Stephanie D Boomkamp, Markus Kipp, Louis Boon, Isabel Bosca, Joel Raffel, Sharmilee Gnanapavan, Paul van der Valk, Jodie Stephenson, Susan C Barnett, David Baker, Sandra Amor. less
Immunology, 2017 Jul 19; 152(4). PMID: 28718500 Free PMC article.
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The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells.
Hong-Sheng Dai, Nathaniel Griffin, +10 authors, Chelsea Bolyard, Hsiaoyin Charlene Mao, Jianying Zhang, Timothy P Cripe, Tadahiro Suenaga, Hisashi Arase, Ichiro Nakano, E A Chiocca, Balveen Kaur, Jianhua Yu, Michael A Caligiuri. less
Immunity, 2017 Jul 21; 47(1). PMID: 28723548 Free PMC article.
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A pilot study on using rapamycin-carrying synthetic vaccine particles (SVP) in conjunction with enzyme replacement therapy to induce immune tolerance in Pompe disease.
Han-Hyuk Lim, Haiqing Yi, +3 authors, Takashi K Kishimoto, Fengqin Gao, Baodong Sun, Priya S Kishnani. less
Mol Genet Metab Rep, 2017 Aug 02; 13. PMID: 28761815 Free PMC article.
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Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis.
Rosa Molfetta, Linda Quatrini, Angela Santoni, Rossella Paolini.
Int J Mol Sci, 2017 Aug 03; 18(8). PMID: 28767057 Free PMC article.
Review.
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IgG cooperativity - Is there allostery? Implications for antibody functions and therapeutic antibody development.
Danlin Yang, Rachel Kroe-Barrett, +2 authors, Sanjaya Singh, Christopher J Roberts, Thomas M Laue. less
MAbs, 2017 Aug 17; 9(8). PMID: 28812955 Free PMC article.
Review.
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Therapeutic Potential of Intravenous Immunoglobulin in Acute Brain Injury.
Vivien Thom, Thiruma V Arumugam, Tim Magnus, Mathias Gelderblom.
Front Immunol, 2017 Aug 22; 8. PMID: 28824617 Free PMC article.
Review.
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IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement.
A D van Dam, L van Beek, +10 authors, A C M Pronk, S M van den Berg, J Van den Bossche, M P J de Winther, F Koning, C van Kooten, P C N Rensen, M R Boon, J S Verbeek, K Willems van Dijk, V van Harmelen. less
Int J Obes (Lond), 2017 Aug 31; 42(2). PMID: 28852207
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Therapeutic Antibodies against Intracellular Tumor Antigens.
Iva Trenevska, Demin Li, Alison H Banham.
Front Immunol, 2017 Sep 05; 8. PMID: 28868054 Free PMC article.
Review.
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(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fcγ receptor signaling.
Qing Qi, Heng Li, +11 authors, Ze-Min Lin, Xiao-Qian Yang, Feng-Hua Zhu, Yu-Ting Liu, Mei-Juan Shao, Lu-Yao Zhang, Yan-Sheng Xu, Yu-Xi Yan, Lan-Lan Sun, Shi-Jun He, Wei Tang, Jian-Ping Zuo. less
Acta Pharmacol Sin, 2017 Sep 08; 39(1). PMID: 28880016 Free PMC article.
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Natural Killer (NK) Cell Education Differentially Influences HIV Antibody-Dependent NK Cell Activation and Antibody-Dependent Cellular Cytotoxicity.
Nicole F Bernard, Zahra Kiani, +3 authors, Alexandra Tremblay-McLean, Sanket A Kant, Christopher E Leeks, Franck P Dupuy. less
Front Immunol, 2017 Sep 09; 8. PMID: 28883824 Free PMC article.
Review.
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Male-specific association of the FCGR2A His167Arg polymorphism with Kawasaki disease.
Young-Chang Kwon, Jae-Jung Kim, +19 authors, Sin Weon Yun, Jeong Jin Yu, Kyung Lim Yoon, Kyung-Yil Lee, Hong-Ryang Kil, Gi Beom Kim, Myung-Ki Han, Min Seob Song, Hyoung Doo Lee, Kee-Soo Ha, Sejung Sohn, Ryota Ebata, Hiromichi Hamada, Hiroyuki Suzuki, Kaoru Ito, Yoshihiro Onouchi, Young Mi Hong, Gi Young Jang, Jong-Keuk Lee, Korean Kawasaki Disease Genetics Consortium. less
PLoS One, 2017 Sep 09; 12(9). PMID: 28886140 Free PMC article.
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Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases.
Hiroshi Nishi, Kazuhiro Furuhashi, +14 authors, Xavier Cullere, Gurpanna Saggu, Mark J Miller, Yunfeng Chen, Florencia Rosetti, Samantha L Hamilton, Lihua Yang, Spencer P Pittman, Jiexi Liao, Jan M Herter, Jeffrey C Berry, Daniel J DeAngelo, Cheng Zhu, George C Tsokos, Tanya N Mayadas. less
J Clin Invest, 2017 Sep 12; 127(10). PMID: 28891817 Free PMC article.
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Biodegradable Viral Nanoparticle/Polymer Implants Prepared via Melt-Processing.
Parker W Lee, Sourabh Shukla, +4 authors, Jaqueline D Wallat, Chaitanya Danda, Nicole F Steinmetz, Joao Maia, Jonathan K Pokorski. less
ACS Nano, 2017 Sep 14; 11(9). PMID: 28902491 Free PMC article.
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Syk-dependent tyrosine phosphorylation of 3BP2 is required for optimal FcRγ-mediated phagocytosis and chemokine expression in U937 cells.
Kazuyasu Chihara, Yuji Kato, +3 authors, Hatsumi Yoshiki, Kenji Takeuchi, Shigeharu Fujieda, Kiyonao Sada. less
Sci Rep, 2017 Sep 15; 7(1). PMID: 28904407 Free PMC article.
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Differential antibody glycosylation in autoimmunity: sweet biomarker or modulator of disease activity?
Michaela Seeling, Christin Brückner, Falk Nimmerjahn.
Nat Rev Rheumatol, 2017 Sep 15; 13(10). PMID: 28905852
Review.
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Correlation between cell aggregation and antibody production in IgE-producing plasma cells.
Mari Hikosaka, Akihiko Murata, Miya Yoshino, Shin-Ichi Hayashi.
Biochem Biophys Rep, 2017 Sep 29; 10. PMID: 28955750 Free PMC article.
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Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields.
Kristina M Ilieva, Judit Fazekas-Singer, +16 authors, Daniela Y Achkova, Tihomir S Dodev, Silvia Mele, Silvia Crescioli, Heather J Bax, Anthony Cheung, Panagiotis Karagiannis, Isabel Correa, Mariangela Figini, Rebecca Marlow, Debra H Josephs, Andrew J Beavil, John Maher, James F Spicer, Erika Jensen-Jarolim, Andrew N Tutt, Sophia N Karagiannis. less
Front Immunol, 2017 Sep 30; 8. PMID: 28959256 Free PMC article.
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Rapid screening of IgG quality attributes - effects on Fc receptor binding.
Karin P M Geuijen, Cindy Oppers-Tiemissen, +4 authors, David F Egging, Peter J Simons, Louis Boon, Richard B M Schasfoort, Michel H M Eppink. less
FEBS Open Bio, 2017 Oct 06; 7(10). PMID: 28979843 Free PMC article.
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IgG Fc engineering to modulate antibody effector functions.
Xinhua Wang, Mary Mathieu, Randall J Brezski.
Protein Cell, 2017 Oct 08; 9(1). PMID: 28986820 Free PMC article.
Highly Cited. Review.
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Designer α1,6-Fucosidase Mutants Enable Direct Core Fucosylation of Intact N-Glycopeptides and N-Glycoproteins.
Chao Li, Shilei Zhu, Christopher Ma, Lai-Xi Wang.
J Am Chem Soc, 2017 Oct 11; 139(42). PMID: 28990779 Free PMC article.
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Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice.
Wenqian He, Chi-Jene Chen, +13 authors, Caitlin E Mullarkey, Jennifer R Hamilton, Christine K Wong, Paul E Leon, Melissa B Uccellini, Veronika Chromikova, Carole Henry, Kevin W Hoffman, Jean K Lim, Patrick C Wilson, Matthew S Miller, Florian Krammer, Peter Palese, Gene S Tan. less
Nat Commun, 2017 Oct 12; 8(1). PMID: 29018261 Free PMC article.
Highly Cited.
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Complement-Activating Anti-HLA Antibodies in Kidney Transplantation: Allograft Gene Expression Profiling and Response to Treatment.
Carmen Lefaucheur, Denis Viglietti, +22 authors, Luis G Hidalgo, Lloyd E Ratner, Serena M Bagnasco, Ibrahim Batal, Olivier Aubert, Babak J Orandi, Federico Oppenheimer, Oriol Bestard, Paolo Rigotti, Anna V Reisaeter, Nassim Kamar, Yvon Lebranchu, Jean-Paul Duong Van Huyen, Patrick Bruneval, Denis Glotz, Christophe Legendre, Jean-Philippe Empana, Xavier Jouven, Dorry L Segev, Robert A Montgomery, Adriana Zeevi, Philip F Halloran, Alexandre Loupy. less
J Am Soc Nephrol, 2017 Oct 19; 29(2). PMID: 29042454 Free PMC article.
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IFNγ Enhances CD64-Potentiated Phagocytosis of Treponema pallidum Opsonized with Human Syphilitic Serum by Human Macrophages.
Kelly L Hawley, Adriana R Cruz, +9 authors, Sarah J Benjamin, Carson J La Vake, Jorge L Cervantes, Morgan LeDoyt, Lady G Ramirez, Daniza Mandich, Mary Fiel-Gan, Melissa J Caimano, Justin D Radolf, Juan C Salazar. less
Front Immunol, 2017 Oct 21; 8. PMID: 29051759 Free PMC article.
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Beyond binding: antibody effector functions in infectious diseases.
Lenette L Lu, Todd J Suscovich, Sarah M Fortune, Galit Alter.
Nat Rev Immunol, 2017 Oct 25; 18(1). PMID: 29063907 Free PMC article.
Highly Cited. Review.
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Recombinant Antibodies to Arm Cytotoxic Lymphocytes in Cancer Immunotherapy.
Joachim Koch, Michael Tesar.
Transfus Med Hemother, 2017 Oct 27; 44(5). PMID: 29070979 Free PMC article.
Review.
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Enavatuzumab, a Humanized Anti-TWEAK Receptor Monoclonal Antibody, Exerts Antitumor Activity through Attracting and Activating Innate Immune Effector Cells.
Shiming Ye, Melvin I Fox, +8 authors, Nicole A Belmar, Mien Sho, Debra T Chao, Donghee Choi, Yuni Fang, Vivian Zhao, Stephen F Keller, Gary C Starling, Patricia A Culp. less
J Immunol Res, 2017 Oct 28; 2017. PMID: 29075649 Free PMC article.
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Pro-inflammatory State in Monoclonal Gammopathy of Undetermined Significance and in Multiple Myeloma Is Characterized by Low Sialylation of Pathogen-Specific and Other Monoclonal Immunoglobulins.
Adrien Bosseboeuf, Sophie Allain-Maillet, +13 authors, Nicolas Mennesson, Anne Tallet, Cédric Rossi, Laurent Garderet, Denis Caillot, Philippe Moreau, Eric Piver, François Girodon, Hélène Perreault, Sophie Brouard, Arnaud Nicot, Edith Bigot-Corbel, Sylvie Hermouet, Jean Harb. less
Front Immunol, 2017 Nov 04; 8. PMID: 29098000 Free PMC article.
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Autoimmunity and autoinflammation: A systems view on signaling pathway dysregulation profiles.
Arsen Arakelyan, Lilit Nersisyan, +5 authors, David Poghosyan, Lusine Khondkaryan, Anna Hakobyan, Henry Löffler-Wirth, Evie Melanitou, Hans Binder. less
PLoS One, 2017 Nov 04; 12(11). PMID: 29099860 Free PMC article.
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Tuberculosis State Is Associated with Expression of Toll-Like Receptor 2 in Sputum Macrophages.
Karim Lakehal, David Levine, +5 authors, Kathleen F Kerr, Pooja Vir, Natalie Bruiners, Alfred Lardizabal, Maria Laura Gennaro, Richard Pine. less
mSphere, 2017 Nov 07; 2(6). PMID: 29104936 Free PMC article.
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Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway.
Elisa Benedetti, Maja Pučić-Baković, +28 authors, Toma Keser, Annika Wahl, Antti Hassinen, Jeong-Yeh Yang, Lin Liu, Irena Trbojević-Akmačić, Genadij Razdorov, Jerko Štambuk, Lucija Klarić, Ivo Ugrina, Maurice H J Selman, Manfred Wuhrer, Igor Rudan, Ozren Polasek, Caroline Hayward, Harald Grallert, Konstantin Strauch, Annette Peters, Thomas Meitinger, Christian Gieger, Marija Vilaj, Geert-Jan Boons, Kelley W Moremen, Tatiana Ovchinnikova, Nicolai Bovin, Sakari Kellokumpu, Fabian J Theis, Gordan Lauc, Jan Krumsiek. less
Nat Commun, 2017 Nov 15; 8(1). PMID: 29133956 Free PMC article.
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IVIG activates FcγRIIB-SHIP1-PIP3 Pathway to stabilize mast cells and suppress inflammation after ICH in mice.
Gokce Yilmaz Akyol, Anatol Manaenko, +6 authors, Onat Akyol, Ihsan Solaroglu, Wing Mann Ho, Yan Ding, Jerry Flores, John H Zhang, Jiping Tang. less
Sci Rep, 2017 Nov 16; 7(1). PMID: 29138419 Free PMC article.
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Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection.
Lucien H Turner, Jeremy M Kinder, +5 authors, Adrienne Wilburn, Rahul J D'Mello, Makayla R Braunlin, Tony T Jiang, Giang Pham, Sing Sing Way. less
PLoS Pathog, 2017 Nov 18; 13(11). PMID: 29145516 Free PMC article.
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Generation and characterization of cross neutralizing human monoclonal antibody against 4 serotypes of dengue virus without enhancing activity.
Subenya Injampa, Nataya Muenngern, +6 authors, Chonlatip Pipattanaboon, Surachet Benjathummarak, Khwanchit Boonha, Hathairad Hananantachai, Waranya Wongwit, Pongrama Ramasoota, Pannamthip Pitaksajjakul. less
PeerJ, 2017 Nov 21; 5. PMID: 29152418 Free PMC article.
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Interplay between Natural Killer Cells and Anti-HER2 Antibodies: Perspectives for Breast Cancer Immunotherapy.
Aura Muntasell, Mariona Cabo, +6 authors, Sonia Servitja, Ignasi Tusquets, María Martínez-García, Ana Rovira, Federico Rojo, Joan Albanell, Miguel López-Botet. less
Front Immunol, 2017 Nov 29; 8. PMID: 29181007 Free PMC article.
Review.
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From IgG Fusion Proteins to Engineered-Specific Human Regulatory T Cells: A Life of Tolerance.
David W Scott.
Front Immunol, 2017 Nov 29; 8. PMID: 29181011 Free PMC article.
Review.
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Immunotherapeutic efficacy of liposome-encapsulated refined allergen vaccines against Dermatophagoides pteronyssinus allergy.
Urai Chaisri, Anchalee Tungtrongchitr, +6 authors, Nitaya Indrawattana, Panisara Meechan, Watchara Phurttikul, Natt Tasaniyananda, Nawannaporn Saelim, Wanpen Chaicumpa, Nitat Sookrung. less
PLoS One, 2017 Nov 29; 12(11). PMID: 29182623 Free PMC article.
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Next generation antibody drugs: pursuit of the 'high-hanging fruit'.
Paul J Carter, Greg A Lazar.
Nat Rev Drug Discov, 2017 Dec 02; 17(3). PMID: 29192287
Highly Cited. Review.
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Phagosomal transport depends strongly on phagosome size.
S Keller, K Berghoff, H Kress.
Sci Rep, 2017 Dec 08; 7(1). PMID: 29213131 Free PMC article.
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Spoiling for a Fight: B Lymphocytes As Initiator and Effector Populations within Tertiary Lymphoid Organs in Autoimmunity and Transplantation.
Jawaher Alsughayyir, Gavin J Pettigrew, Reza Motallebzadeh.
Front Immunol, 2017 Dec 09; 8. PMID: 29218052 Free PMC article.
Review.
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Increasing the Clinical Potential and Applications of Anti-HIV Antibodies.
Casey K Hua, Margaret E Ackerman.
Front Immunol, 2017 Dec 14; 8. PMID: 29234320 Free PMC article.
Review.
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Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action.
James I Robinson, Euan W Baxter, +13 authors, Robin L Owen, Maren Thomsen, Darren C Tomlinson, Mark P Waterhouse, Stephanie J Win, Joanne E Nettleship, Christian Tiede, Richard J Foster, Raymond J Owens, Colin W G Fishwick, Sarah A Harris, Adrian Goldman, Michael J McPherson, Ann W Morgan. less
Proc Natl Acad Sci U S A, 2017 Dec 17; 115(1). PMID: 29247053 Free PMC article.
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The Role of Estrogen Membrane Receptor (G Protein-Coupled Estrogen Receptor 1) in Skin Inflammation Induced by Systemic Lupus Erythematosus Serum IgG.
Zhenming Cai, Changhao Xie, +8 authors, Wei Qiao, Xibin Fei, Xuanxuan Guo, Huicheng Liu, Xiaoyan Li, Xiang Fang, Guangqiong Xu, Hui Dou, Guo-Min Deng. less
Front Immunol, 2017 Dec 20; 8. PMID: 29255468 Free PMC article.
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Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease.
Jose D Pagan, Maya Kitaoka, Robert M Anthony.
Cell, 2017 Dec 26; 172(3). PMID: 29275858 Free PMC article.
Highly Cited.
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The Phagocytic Function of Macrophage-Enforcing Innate Immunity and Tissue Homeostasis.
Daisuke Hirayama, Tomoya Iida, Hiroshi Nakase.
Int J Mol Sci, 2017 Dec 30; 19(1). PMID: 29286292 Free PMC article.
Highly Cited. Review.
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Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex.
Marianna Stamou, Ana Cristina Grodzki, +2 authors, Marc van Oostrum, Bernd Wollscheid, Pamela J Lein. less
J Neuroinflammation, 2018 Jan 08; 15(1). PMID: 29306331 Free PMC article.
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Development and characterization of an anti-rituximab monoclonal antibody panel.
Minoru Tada, Takuo Suzuki, Akiko Ishii-Watabe.
MAbs, 2018 Jan 09; 10(3). PMID: 29309213 Free PMC article.
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Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals.
Lars Torkel Hellman, Srinivas Akula, Michael Thorpe, Zhirong Fu.
Front Immunol, 2018 Jan 10; 8. PMID: 29312297 Free PMC article.
Review.
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Characterization of novel endo-β-N-acetylglucosaminidases from Sphingobacterium species, Beauveria bassiana and Cordyceps militaris that specifically hydrolyze fucose-containing oligosaccharides and human IgG.
Yibo Huang, Yujiro Higuchi, +3 authors, Takashi Kinoshita, Ai Mitani, Yasunari Eshima, Kaoru Takegawa. less
Sci Rep, 2018 Jan 13; 8(1). PMID: 29321565 Free PMC article.
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Complement pathway gene activation and rising circulating immune complexes characterize early disease in HIV-associated tuberculosis.
Hanif Esmail, Rachel P Lai, +7 authors, Maia Lesosky, Katalin A Wilkinson, Christine M Graham, Stuart Horswell, Anna K Coussens, Clifton E Barry, Anne O'Garra, Robert J Wilkinson. less
Proc Natl Acad Sci U S A, 2018 Jan 18; 115(5). PMID: 29339504 Free PMC article.
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Fc-Mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models.
Sai Kiran Sharma, Andrew Chow, +8 authors, Sebastien Monette, Delphine Vivier, Jacob Pourat, Kimberly J Edwards, Thomas R Dilling, Dalya Abdel-Atti, Brian M Zeglis, John T Poirier, Jason S Lewis. less
Cancer Res, 2018 Jan 25; 78(7). PMID: 29363548 Free PMC article.
Highly Cited.
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iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.
Xiaoping Qing, Yurii Chinenov, +9 authors, Patricia Redecha, Michael Madaio, Joris Jth Roelofs, Gregory Farber, Priya D Issuree, Laura Donlin, David R Mcllwain, Tak W Mak, Carl P Blobel, Jane E Salmon. less
J Clin Invest, 2018 Jan 26; 128(4). PMID: 29369823 Free PMC article.
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Evaluating antibody functional activity and strain-specificity of vaccine candidates for malaria in pregnancy using in vitro phagocytosis assays.
Mirja Hommel, Jo-Anne Chan, +4 authors, Alexandra J Umbers, Christine Langer, Stephen J Rogerson, Joseph D Smith, James G Beeson. less
Parasit Vectors, 2018 Jan 31; 11(1). PMID: 29378634 Free PMC article.
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Eradication of spontaneous malignancy by local immunotherapy.
Idit Sagiv-Barfi, Debra K Czerwinski, +4 authors, Shoshana Levy, Israt S Alam, Aaron T Mayer, Sanjiv S Gambhir, Ronald Levy. less
Sci Transl Med, 2018 Feb 02; 10(426). PMID: 29386357 Free PMC article.
Highly Cited.
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Augmentation of CD134 (OX40)-dependent NK anti-tumour activity is dependent on antibody cross-linking.
Anna H Turaj, Kerry L Cox, +10 authors, Christine A Penfold, Ruth R French, C Ian Mockridge, Jane E Willoughby, Alison L Tutt, Jordana Griffiths, Peter W M Johnson, Martin J Glennie, Ronald Levy, Mark S Cragg, Sean H Lim. less
Sci Rep, 2018 Feb 06; 8(1). PMID: 29396470 Free PMC article.
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Mouse IgG2c Fc loop residues promote greater receptor-binding affinity than mouse IgG2b or human IgG1.
Daniel J Falconer, Adam W Barb.
PLoS One, 2018 Feb 07; 13(2). PMID: 29408873 Free PMC article.
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Screening for key genes and transcription factors in ankylosing spondylitis by RNA-Seq.
Zhongyang Xu, Xiuyu Wang, Yanping Zheng.
Exp Ther Med, 2018 Feb 13; 15(2). PMID: 29434723 Free PMC article.
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Role of Bruton's tyrosine kinase in B cells and malignancies.
Simar Pal Singh, Floris Dammeijer, Rudi W Hendriks.
Mol Cancer, 2018 Feb 20; 17(1). PMID: 29455639 Free PMC article.
Highly Cited. Review.
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FcγRIIa defunctioning polymorphism in paediatric patients with renal allograft.
Fatina I Fadel, Manal F Elshamaa, +4 authors, Ahmed Salah, Eman A Elghoroury, Safaa Abd El-Rahman, Mona Hamed Ibrahim, Solaf Kamel. less
Cent Eur J Immunol, 2018 Feb 24; 42(4). PMID: 29472814 Free PMC article.
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Evaluation of analytical similarity between trastuzumab biosimilar CT-P6 and reference product using statistical analyses.
Jihun Lee, Hyun Ah Kang, +5 authors, Jin Soo Bae, Kyu Dae Kim, Kyoung Hoon Lee, Ki Jung Lim, Min Joo Choo, Shin Jae Chang. less
MAbs, 2018 Feb 28; 10(4). PMID: 29482416 Free PMC article.
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Molecular Basis for the Recognition of Herpes Simplex Virus Type 1 Infection by Human Natural Killer Cells.
Hong-Sheng Dai, Michael A Caligiuri.
Front Immunol, 2018 Feb 28; 9. PMID: 29483911 Free PMC article.
Review.
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Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues.
Kutty Selva Nandakumar.
Int J Mol Sci, 2018 Mar 03; 19(3). PMID: 29495570 Free PMC article.
Review.
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Transmembrane domain dependent inhibitory function of FcγRIIB.
Junyi Wang, Zongyu Li, +2 authors, Liling Xu, Hengwen Yang, Wanli Liu. less
Protein Cell, 2018 Mar 03; 9(12). PMID: 29497990 Free PMC article.
Review.
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Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell-mediated cytotoxicity assay.
Justin Pollara, Chiara Orlandi, +11 authors, Charles Beck, R Whitney Edwards, Yi Hu, Shuying Liu, Shixia Wang, Richard A Koup, Thomas N Denny, Shan Lu, Georgia D Tomaras, Anthony DeVico, George K Lewis, Guido Ferrari. less
Cytometry A, 2018 Mar 03; 93(4). PMID: 29498807 Free PMC article.
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Decreased IgG4 ACPA levels in responders and increased CD1c+ classical dendritic cells in non-responders of patients with rheumatoid arthritis under therapy.
Robby Engelmann, Sven Nekarda, +2 authors, Daniela Kuthning, Christian Kneitz, Brigitte Müller-Hilke. less
Clin Rheumatol, 2018 Mar 05; 37(7). PMID: 29502227
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Natural killer cell cytotoxicity and its regulation by inhibitory receptors.
Santosh Kumar.
Immunology, 2018 Mar 08; 154(3). PMID: 29512837 Free PMC article.
Review.
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Analysis of the association between Fc receptor family gene polymorphisms and ocular Behçet's disease in Han Chinese.
Donglei Zhang, Jieying Qin, +5 authors, Lin Li, Guannan Su, Guo Huang, Qingfeng Cao, Aize Kijlstra, Peizeng Yang. less
Sci Rep, 2018 Mar 21; 8(1). PMID: 29555961 Free PMC article.
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Correlation of natural autoantibodies and cardiovascular disease-related anti-bacterial antibodies in pericardial fluid of cardiac surgery patients.
D Simon, O Gilicze, +4 authors, N Farkas, J Najbauer, P Németh, L Lénárd, T Berki. less
Clin Exp Immunol, 2018 Mar 25; 193(1). PMID: 29573404 Free PMC article.
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A Chimeric Antibody against ACKR3/CXCR7 in Combination with TMZ Activates Immune Responses and Extends Survival in Mouse GBM Models.
Nicole Salazar, Jeffrey C Carlson, +14 authors, Kexin Huang, Yayue Zheng, Cecilia Oderup, Julia Gross, Andrew D Jang, Thomas M Burke, Susanna Lewén, Alexander Scholz, Serina Huang, Leona Nease, Jon Kosek, Michel Mittelbronn, Eugene C Butcher, Hua Tu, Brian A Zabel. less
Mol Ther, 2018 Apr 03; 26(5). PMID: 29606504 Free PMC article.
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Antibody-Dependent Cellular Phagocytosis by Macrophages is a Novel Mechanism of Action of Elotuzumab.
Ahmed T Kurdi, Siobhan V Glavey, +14 authors, Natalie A Bezman, Amy Jhatakia, Jennifer L Guerriero, Salomon Manier, Michele Moschetta, Yuji Mishima, Aldo Roccaro, Alexandre Detappe, Chia-Jen Liu, Antonio Sacco, Daisy Huynh, Yu-Tzu Tai, Michael D Robbins, Jamil Azzi, Irene M Ghobrial. less
Mol Cancer Ther, 2018 Apr 15; 17(7). PMID: 29654064 Free PMC article.
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IgG and leukocytes: Targets of immunomodulatory α2,6 sialic acids.
Mark B Jones.
Cell Immunol, 2018 Apr 25; 333. PMID: 29685495 Free PMC article.
Review.
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Artificial Anti-Tumor Opsonizing Proteins with Fibronectin Scaffolds Engineered for Specificity to Each of the Murine FcγR Types.
Tiffany F Chen, Kevin K Li, +5 authors, Eric F Zhu, Cary F Opel, Monique J Kauke, Heeyoon Kim, Eta Atolia, K Dane Wittrup. less
J Mol Biol, 2018 Apr 29; 430(12). PMID: 29704491 Free PMC article.
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Multilayer Control of B Cell Activation by the B Cell Antigen Receptor: Following Themes Initiated With Bill Paul.
Anthony L DeFranco.
Front Immunol, 2018 May 10; 9. PMID: 29740430 Free PMC article.
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Targeting B Cells and Plasma Cells in Autoimmune Diseases.
Katharina Hofmann, Ann-Katrin Clauder, Rudolf Armin Manz.
Front Immunol, 2018 May 10; 9. PMID: 29740441 Free PMC article.
Highly Cited. Review.
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Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S.
Beatriz Trastoy, Erik Klontz, +4 authors, Jared Orwenyo, Alberto Marina, Lai-Xi Wang, Eric J Sundberg, Marcelo E Guerin. less
Nat Commun, 2018 May 16; 9(1). PMID: 29760474 Free PMC article.
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Immunization With Fc-Based Recombinant Epstein-Barr Virus gp350 Elicits Potent Neutralizing Humoral Immune Response in a BALB/c Mice Model.
Bingchun Zhao, Xiao Zhang, +9 authors, Claude Krummenacher, Shuo Song, Ling Gao, Haojiong Zhang, Miao Xu, Lin Feng, Qisheng Feng, Musheng Zeng, Yuting Xu, Yixin Zeng. less
Front Immunol, 2018 May 17; 9. PMID: 29765376 Free PMC article.
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CD32-Expressing CD4 T Cells Are Phenotypically Diverse and Can Contain Proviral HIV DNA.
Genevieve E Martin, Matthew Pace, +15 authors, John P Thornhill, Chansavath Phetsouphanh, Jodi Meyerowitz, Morgane Gossez, Helen Brown, Natalia Olejniczak, Julianne Lwanga, Gita Ramjee, Pontiano Kaleebu, Kholoud Porter, Christian B Willberg, Paul Klenerman, Nneka Nwokolo, Julie Fox, Sarah Fidler, John Frater. less
Front Immunol, 2018 May 22; 9. PMID: 29780387 Free PMC article.
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Molecular and Functional Characterization of Fcγ Receptor IIIb-Ligand Interaction: Implications for Neutrophil-Mediated Immune Mechanisms in Malaria.
Piyapong Simtong, Amornrat V Romphruk, +8 authors, Annalena Traum, Monika Burg-Roderfeld, Gregor Bein, Konstantin Jakubowski, Andreas Dominik, Michael Theisen, Ikhlaq Hussain Kana, Ulrich J Sachs, Sentot Santoso. less
Infect Immun, 2018 May 23; 86(8). PMID: 29784860 Free PMC article.
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Correlation of Lyme Disease-Associated IgG4 Autoantibodies With Synovial Pathology in Antibiotic-Refractory Lyme Arthritis.
Katherine B Sulka, Klemen Strle, +3 authors, Jameson T Crowley, Robert B Lochhead, Robert Anthony, Allen C Steere. less
Arthritis Rheumatol, 2018 May 24; 70(11). PMID: 29790305 Free PMC article.
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Potential of Murine IgG1 and Human IgG4 to Inhibit the Classical Complement and Fcγ Receptor Activation Pathways.
Gina-Maria Lilienthal, Johann Rahmöller, +3 authors, Janina Petry, Yannic C Bartsch, Alexei Leliavski, Marc Ehlers. less
Front Immunol, 2018 Jun 06; 9. PMID: 29867943 Free PMC article.
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Intracapillary immune complexes recruit and activate slan-expressing CD16+ monocytes in human lupus nephritis.
Florina Olaru, Thomas Döbel, +7 authors, Anke S Lonsdorf, Stephanie Oehrl, Michael Maas, Alexander H Enk, Marc Schmitz, Elisabeth F Gröne, Hermann-J Gröne, Knut Schäkel. less
JCI Insight, 2018 Jun 08; 3(11). PMID: 29875315 Free PMC article.
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IGHG, IGKC, and FCGR genes and endogenous antibody responses to GARP in patients with breast cancer and matched controls.
Janardan P Pandey, Aryan M Namboodiri, +4 authors, Kent E Armeson, Motoki Iwasaki, Yoshio Kasuga, Gerson S Hamada, Shoichiro Tsugane. less
Hum Immunol, 2018 Jun 08; 79(8). PMID: 29879453 Free PMC article.
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Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T Cell Antigens.
Jeremy D Waight, Dhan Chand, +14 authors, Sylvia Dietrich, Randi Gombos, Thomas Horn, Ana M Gonzalez, Mariana Manrique, Lukasz Swiech, Benjamin Morin, Christine Brittsan, Antoine Tanne, Belinda Akpeng, Ben A Croker, Jennifer S Buell, Robert Stein, David A Savitsky, Nicholas S Wilson. less
Cancer Cell, 2018 Jun 13; 33(6). PMID: 29894690 Free PMC article.
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Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection.
Jason D Simmons, Catherine M Stein, +9 authors, Chetan Seshadri, Monica Campo, Galit Alter, Sarah Fortune, Erwin Schurr, Robert S Wallis, Gavin Churchyard, Harriet Mayanja-Kizza, W Henry Boom, Thomas R Hawn. less
Nat Rev Immunol, 2018 Jun 14; 18(9). PMID: 29895826 Free PMC article.
Highly Cited. Review.
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The promise and challenges of immune agonist antibody development in cancer.
Patrick A Mayes, Kenneth W Hance, Axel Hoos.
Nat Rev Drug Discov, 2018 Jun 16; 17(7). PMID: 29904196
Highly Cited. Review.
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Sialylated Autoantigen-Reactive IgG Antibodies Attenuate Disease Development in Autoimmune Mouse Models of Lupus Nephritis and Rheumatoid Arthritis.
Yannic C Bartsch, Johann Rahmöller, +17 authors, Maria M M Mertes, Susanne Eiglmeier, Felix K M Lorenz, Alexander D Stoehr, Dominique Braumann, Alexandra K Lorenz, André Winkler, Gina-Maria Lilienthal, Janina Petry, Juliane Hobusch, Moritz Steinhaus, Constanze Hess, Vivien Holecska, Carolin T Schoen, Carolin M Oefner, Alexei Leliavski, Véronique Blanchard, Marc Ehlers. less
Front Immunol, 2018 Jun 22; 9. PMID: 29928274 Free PMC article.
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Tissue-Specific Expression of the Low-Affinity IgG Receptor, FcγRIIb, on Human Mast Cells.
Oliver T Burton, Alexandra Epp, +6 authors, Manoussa E Fanny, Samuel J Miller, Amanda J Stranks, Jessica E Teague, Rachael A Clark, Matt van de Rijn, Hans C Oettgen. less
Front Immunol, 2018 Jun 22; 9. PMID: 29928276 Free PMC article.
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Extending human IgG half-life using structure-guided design.
Brian J Booth, Boopathy Ramakrishnan, +4 authors, Kristin Narayan, Andrew M Wollacott, Gregory J Babcock, Zachary Shriver, Karthik Viswanathan. less
MAbs, 2018 Jun 28; 10(7). PMID: 29947573 Free PMC article.
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Size-Dependent Segregation Controls Macrophage Phagocytosis of Antibody-Opsonized Targets.
Matthew H Bakalar, Aaron M Joffe, +3 authors, Eva M Schmid, Sungmin Son, Marija Podolski, Daniel A Fletcher. less
Cell, 2018 Jun 30; 174(1). PMID: 29958103 Free PMC article.
Highly Cited.
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Anti-ADAM17 monoclonal antibody MEDI3622 increases IFNγ production by human NK cells in the presence of antibody-bound tumor cells.
Hemant K Mishra, Nabendu Pore, Emil F Michelotti, Bruce Walcheck.
Cancer Immunol Immunother, 2018 Jul 07; 67(9). PMID: 29978334 Free PMC article.
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Effects of Bovine Immunoglobulins on Immune Function, Allergy, and Infection.
Laurien H Ulfman, Jeanette H W Leusen, +2 authors, Huub F J Savelkoul, John O Warner, R J Joost van Neerven. less
Front Nutr, 2018 Jul 11; 5. PMID: 29988421 Free PMC article.
Review.
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Analysis of protein-protein interaction network based on transcriptome profiling of ovine granulosa cells identifies candidate genes in cyclic recruitment of ovarian follicles.
Reza Talebi, Ahmad Ahmadi, Fazlollah Afraz.
J Anim Sci Technol, 2018 Jul 12; 60. PMID: 29992036 Free PMC article.
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Evaluating Anti-CD32b F(ab) Conformation Using Molecular Dynamics and Small-Angle X-Ray Scattering.
Emma J Sutton, Richard T Bradshaw, +6 authors, Christian M Orr, Bjorn Frendéus, Gunilla Larsson, Ingrid Teige, Mark S Cragg, Ivo Tews, Jonathan W Essex. less
Biophys J, 2018 Jul 19; 115(2). PMID: 30021105 Free PMC article.
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Kaposi's Sarcoma-Associated Herpesvirus Latency Locus Renders B Cells Hyperresponsive to Secondary Infections.
Sang-Hoon Sin, Anthony B Eason, +7 authors, Rachele Bigi, Yongbaek Kim, SunAh Kang, Kelly Tan, Tischan A Seltzer, Raman Venkataramanan, Hyowon An, Dirk P Dittmer. less
J Virol, 2018 Jul 20; 92(19). PMID: 30021906 Free PMC article.
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T-Bet+ IgM Memory Cells Generate Multi-lineage Effector B Cells.
Kevin J Kenderes, Russell C Levack, +3 authors, Amber M Papillion, Berenice Cabrera-Martinez, Lisa M Dishaw, Gary M Winslow. less
Cell Rep, 2018 Jul 26; 24(4). PMID: 30044980 Free PMC article.
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Higher Serum Immunoglobulin G3 Levels May Predict the Development of Multiple Sclerosis in Individuals With Clinically Isolated Syndrome.
Stephanie Trend, Anderson P Jones, +10 authors, Lilian Cha, Scott N Byrne, Sian Geldenhuys, Marzena J Fabis-Pedrini, William M Carroll, Judith M Cole, David R Booth, Robyn M Lucas, Allan G Kermode, Martyn A French, Prue H Hart. less
Front Immunol, 2018 Jul 31; 9. PMID: 30057580 Free PMC article.
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Aggregates of IVIG or Avastin, but not HSA, modify the response to model innate immune response modulating impurities.
Swamy Kumar Polumuri, Lydia A Haile, Derek D C Ireland, Daniela Verthelyi.
Sci Rep, 2018 Aug 02; 8(1). PMID: 30065306 Free PMC article.
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Characterization of peritoneal cells from cats with experimentally-induced feline infectious peritonitis (FIP) using RNA-seq.
Rie Watanabe, Christina Eckstrand, Hongwei Liu, Niels C Pedersen.
Vet Res, 2018 Aug 09; 49(1). PMID: 30086792 Free PMC article.
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Circulating and intrahepatic antiviral B cells are defective in hepatitis B.
Alice R Burton, Laura J Pallett, +11 authors, Laura E McCoy, Kornelija Suveizdyte, Oliver E Amin, Leo Swadling, Elena Alberts, Brian R Davidson, Patrick Tf Kennedy, Upkar S Gill, Claudia Mauri, Paul A Blair, Nadege Pelletier, Mala K Maini. less
J Clin Invest, 2018 Aug 10; 128(10). PMID: 30091725 Free PMC article.
Highly Cited.
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The DNA-polymorphism rs849142 is associated with skin toxicity induced by targeted anti-EGFR therapy using cetuximab.
Matthias F Froelich, Sebastian Stintzing, +5 authors, Jörg Kumbrink, Thomas G P Grünewald, Ulrich Mansmann, Volker Heinemann, Thomas Kirchner, Andreas Jung. less
Oncotarget, 2018 Aug 14; 9(54). PMID: 30100989 Free PMC article.
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Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors.
Natalia A Kuzmina, Patrick Younan, +8 authors, Pavlo Gilchuk, Rodrigo I Santos, Andrew I Flyak, Philipp A Ilinykh, Kai Huang, Ndongala M Lubaki, Palaniappan Ramanathan, James E Crowe, Alexander Bukreyev. less
Cell Rep, 2018 Aug 16; 24(7). PMID: 30110637 Free PMC article.
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The protein tyrosine phosphatase PTPN22 negatively regulates presentation of immune complex derived antigens.
Fiona Clarke, Harriet A Purvis, +5 authors, Cristina Sanchez-Blanco, Enrique Gutiérrez-Martinez, Georgina H Cornish, Rose Zamoyska, Pierre Guermonprez, Andrew P Cope. less
Sci Rep, 2018 Aug 25; 8(1). PMID: 30139951 Free PMC article.
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Sex Differences in HIV Infection: Mystique Versus Machismo.
Eileen P Scully.
Pathog Immun, 2018 Aug 25; 3(1). PMID: 30140783 Free PMC article.
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Chemoenzymatic Methods for the Synthesis of Glycoproteins.
Chao Li, Lai-Xi Wang.
Chem Rev, 2018 Aug 25; 118(17). PMID: 30141327 Free PMC article.
Highly Cited. Review.
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Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cells.
Melissa Newling, Willianne Hoepel, +11 authors, Lisa T C Vogelpoel, Marieke H Heineke, Johan A van Burgsteden, Esther W M Taanman-Kueter, Dirk Eggink, Taco W Kuijpers, Tim Beaumont, Marjolein van Egmond, Martien L Kapsenberg, Dominique L P Baeten, Jeroen den Dunnen, Esther C de Jong. less
Eur J Immunol, 2018 Sep 06; 48(11). PMID: 30184252 Free PMC article.
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Overexpression of CD64 on CD14++CD16- and CD14++CD16+ monocytes of rheumatoid arthritis patients correlates with disease activity.
Qing Luo, Pengcheng Xiao, +7 authors, Xue Li, Zhen Deng, Cheng Qing, Rigu Su, Jianqing Xu, Yang Guo, Zikun Huang, Junming Li. less
Exp Ther Med, 2018 Sep 14; 16(3). PMID: 30210612 Free PMC article.
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CD38 Antibodies in Multiple Myeloma: Mechanisms of Action and Modes of Resistance.
Niels W C J van de Donk, Saad Z Usmani.
Front Immunol, 2018 Oct 09; 9. PMID: 30294326 Free PMC article.
Highly Cited. Review.
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Adjuvanted Immunotherapy Approaches for Peanut Allergy.
Brandi T Johnson-Weaver, Herman F Staats, A Wesley Burks, Michael D Kulis.
Front Immunol, 2018 Oct 16; 9. PMID: 30319619 Free PMC article.
Review.
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A phosphatidylinositol 4,5-bisphosphate redistribution-based sensing mechanism initiates a phagocytosis programing.
Libing Mu, Zhongyuan Tu, +12 authors, Lin Miao, Hefei Ruan, Ning Kang, Yongzhen Hei, Jiahuan Chen, Wei Wei, Fangling Gong, Bingjie Wang, Yanan Du, Guanghui Ma, Matthias W Amerein, Tie Xia, Yan Shi. less
Nat Commun, 2018 Oct 17; 9(1). PMID: 30323235 Free PMC article.
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Antibody-mediated protection against Ebola virus.
Erica Ollmann Saphire, Sharon L Schendel, +2 authors, Bronwyn M Gunn, Jacob C Milligan, Galit Alter. less
Nat Immunol, 2018 Oct 20; 19(11). PMID: 30333617 Free PMC article.
Highly Cited. Review.
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Ligand Recognition Determines the Role of Inhibitory B Cell Co-receptors in the Regulation of B Cell Homeostasis and Autoimmunity.
Takeshi Tsubata.
Front Immunol, 2018 Oct 20; 9. PMID: 30333834 Free PMC article.
Review.
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Tregitope-linked Refined Allergen Vaccines for Immunotherapy in Cockroach Allergy.
Pannathee Prangtaworn, Urai Chaisri, +7 authors, Watee Seesuay, Kodchakorn Mahasongkram, Nattawat Onlamoon, Onrapak Reamtong, Anchalee Tungtrongchitr, Nitaya Indrawattana, Wanpen Chaicumpa, Nitat Sookrung. less
Sci Rep, 2018 Oct 21; 8(1). PMID: 30341299 Free PMC article.
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CD32 Expression is not Associated to HIV-DNA content in CD4 cell subsets of individuals with Different Levels of HIV Control.
Marcial García, María Angeles Navarrete-Muñoz, +11 authors, José M Ligos, Alfonso Cabello, Clara Restrepo, Juan Carlos López-Bernaldo, Francisco Javier de la Hera, Carlos Barros, María Montoya, Manuel Fernández-Guerrero, Vicente Estrada, Miguel Górgolas, José M Benito, Norma Rallón. less
Sci Rep, 2018 Oct 21; 8(1). PMID: 30341387 Free PMC article.
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Critical Role of Macrophage FcγR Signaling and Reactive Oxygen Species in Alloantibody-Mediated Hepatocyte Rejection.
Jason M Zimmerer, Xin L Liu, +4 authors, Alecia Blaszczak, Christina L Avila, Thomas A Pham, Robert T Warren, Ginny L Bumgardner. less
J Immunol, 2018 Nov 07; 201(12). PMID: 30397035 Free PMC article.
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Targeted Intracellular Delivery of Antibodies: The State of the Art.
Tatiana A Slastnikova, A V Ulasov, A A Rosenkranz, A S Sobolev.
Front Pharmacol, 2018 Nov 09; 9. PMID: 30405420 Free PMC article.
Review.
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IgG Glyco-Engineering to Improve IVIg Potency.
Christine W Bruggeman, Gillian Dekkers, +5 authors, Remco Visser, Naneth W M Goes, Timo K van den Berg, Theo Rispens, Gestur Vidarsson, Taco W Kuijpers. less
Front Immunol, 2018 Nov 09; 9. PMID: 30405631 Free PMC article.
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Generation of Highly Efficient Equine-Derived Antibodies for Post-Exposure Treatment of Ricin Intoxications by Vaccination with Monomerized Ricin.
Reut Falach, Anita Sapoznikov, +9 authors, Ron Alcalay, Moshe Aftalion, Sharon Ehrlich, Arik Makovitzki, Avi Agami, Avishai Mimran, Amir Rosner, Tamar Sabo, Chanoch Kronman, Yoav Gal. less
Toxins (Basel), 2018 Nov 15; 10(11). PMID: 30424519 Free PMC article.
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Altered circulating levels of B cell growth factors and their modulation upon anti-tuberculosis treatment in pulmonary tuberculosis and tuberculous lymphadenitis.
Gokul Raj Kathamuthu, Kadar Moideen, +4 authors, Vaithilingam V Banurekha, Dina Nair, R Sridhar, Dhanaraj Baskaran, Subash Babu. less
PLoS One, 2018 Nov 15; 13(11). PMID: 30427928 Free PMC article.
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The Development of Serum Amyloid P as a Possible Therapeutic.
Darrell Pilling, Richard H Gomer.
Front Immunol, 2018 Nov 22; 9. PMID: 30459752 Free PMC article.
Review.
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Fucosyl-Agalactosyl IgG₁ Induces Cholangiocarcinoma Metastasis and Early Recurrence by Activating Tumor-Associated Macrophage.
Ting-Tsung Chang, Hung-Wen Tsai, Cheng-Hsun Ho.
Cancers (Basel), 2018 Nov 25; 10(11). PMID: 30469416 Free PMC article.
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Pentraxins and Fc Receptor-Mediated Immune Responses.
Jinghua Lu, Carolyn Mold, Terry W Du Clos, Peter D Sun.
Front Immunol, 2018 Nov 30; 9. PMID: 30483265 Free PMC article.
Review.
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Gene Regulatory Network Modeling of Macrophage Differentiation Corroborates the Continuum Hypothesis of Polarization States.
Alessandro Palma, Abdul Salam Jarrah, +2 authors, Paolo Tieri, Gianni Cesareni, Filippo Castiglione. less
Front Physiol, 2018 Dec 14; 9. PMID: 30546316 Free PMC article.
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Landscape of B cell immunity and related immune evasion in human cancers.
Xihao Hu, Jian Zhang, +17 authors, Jin Wang, Jingxin Fu, Taiwen Li, Xiaoqi Zheng, Binbin Wang, Shengqing Gu, Peng Jiang, Jingyu Fan, Xiaomin Ying, Jing Zhang, Michael C Carroll, Kai W Wucherpfennig, Nir Hacohen, Fan Zhang, Peng Zhang, Jun S Liu, Bo Li, X Shirley Liu. less
Nat Genet, 2019 Feb 12; 51(3). PMID: 30742113 Free PMC article.
Highly Cited.
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Role of ADAM17 as a regulatory checkpoint of CD16A in NK cells and as a potential target for cancer immunotherapy.
Jianming Wu, Hemant K Mishra, Bruce Walcheck.
J Leukoc Biol, 2019 Feb 21; 105(6). PMID: 30786043 Free PMC article.
Highly Cited. Review.
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Antibody responses to viral infections: a structural perspective across three different enveloped viruses.
Charles D Murin, Ian A Wilson, Andrew B Ward.
Nat Microbiol, 2019 Mar 20; 4(5). PMID: 30886356 Free PMC article.
Review.
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Decreased expression of FcγRII in active Graves' disease patients.
Xixuan Lu, Shiqiao Peng, +2 authors, Xinyi Wang, Zhongyan Shan, Weiping Teng. less
J Clin Lab Anal, 2019 Apr 30; 33(6). PMID: 31033004 Free PMC article.
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Asparaginase immune complexes induce Fc-γRIII-dependent hypersensitivity in naive mice.
Sanjay Rathod, Manda Ramsey, +3 authors, Danielle DiGiorgio, Roberto Berrios, Fred D Finkelman, Christian A Fernandez. less
FASEB J, 2019 Jul 10; 33(10). PMID: 31284767 Free PMC article.
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Effects of BTK signalling in pathogenic microorganism infections.
Bingjue Ye, Cheng Zhou, Huiting Guo, Min Zheng.
J Cell Mol Med, 2019 Aug 10; 23(10). PMID: 31397086 Free PMC article.
Review.
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Dual effects of an anti-CD147 antibody for Esophageal cancer therapy.
Miao Wang, Shuai Zhang, +6 authors, Qian Sun, Xiangmin Yang, Yu Wang, Runze Shang, Yumeng Zhu, Hui Yao, Yu Li. less
Cancer Biol Ther, 2019 Aug 15; 20(12). PMID: 31411555 Free PMC article.
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Fc Gamma Receptor Polymorphisms Modulated the Vaccine Effect on HIV-1 Risk in the HVTN 505 HIV Vaccine Trial.
Shuying S Li, Peter B Gilbert, +21 authors, Lindsay N Carpp, Chul-Woo Pyo, Holly Janes, Youyi Fong, Xiaoying Shen, Scott D Neidich, Derrick Goodman, Allan deCamp, Kristen W Cohen, Guido Ferrari, Scott M Hammer, Magdalena E Sobieszczyk, Mark J Mulligan, Susan P Buchbinder, Michael C Keefer, Edwin DeJesus, Richard M Novak, Ian Frank, M Juliana McElrath, Georgia D Tomaras, Daniel E Geraghty, Xinxia Peng. less
J Virol, 2019 Aug 23; 93(21). PMID: 31434737 Free PMC article.
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A distinct subset of FcγRI-expressing Th1 cells exert antibody-mediated cytotoxic activity.
Diana Rasoulouniriana, Nadine Santana-Magal, +11 authors, Amit Gutwillig, Leen Farhat-Younis, Yariv Wine, Corey Saperia, Lior Tal, Haim Gutman, Alexander Tsivian, Ronen Brenner, Eiman Abu Bandora, Nathan E Reticker-Flynn, Peleg Rider, Yaron Carmi. less
J Clin Invest, 2019 Aug 27; 129(10). PMID: 31449054 Free PMC article.
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Understudied Factors Influencing Fc-Mediated Immune Responses against Viral Infections.
Sai Priya Anand, Andrés Finzi.
Vaccines (Basel), 2019 Sep 05; 7(3). PMID: 31480293 Free PMC article.
Review.
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HIV and Solid Organ Transplantation: Where Are we Now.
Jean Botha, June Fabian, +2 authors, Harriet Etheredge, Francesca Conradie, Caroline T Tiemessen. less
Curr HIV/AIDS Rep, 2019 Sep 05; 16(5). PMID: 31482298 Free PMC article.
Review.
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Ehrlichia chaffeensis Outer Membrane Protein 1-Specific Human Antibody-Mediated Immunity Is Defined by Intracellular TRIM21-Dependent Innate Immune Activation and Extracellular Neutralization.
Thangam Sudha Velayutham, Sandeep Kumar, +5 authors, Xiaofeng Zhang, Nurgun Kose, David H Walker, Gary Winslow, James E Crowe, Jere W McBride. less
Infect Immun, 2019 Sep 25; 87(12). PMID: 31548319 Free PMC article.
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Differential Effect of Mucosal NKp44+ Innate Lymphoid Cells and Δγ Cells on Simian Immunodeficiency Virus Infection Outcome in Rhesus Macaques.
Mohammad Arif Rahman, Eun-Ju Ko, +6 authors, Gospel Enyindah-Asonye, Sabrina Helmold Hait, Christopher Hogge, Ruth Hunegnaw, David J Venzon, Tanya Hoang, Marjorie Robert-Guroff. less
J Immunol, 2019 Sep 27; 203(9). PMID: 31554692 Free PMC article.
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Mechanisms of Resistance to Monoclonal Antibodies (mAbs) in Lymphoid Malignancies.
Pallawi Torka, Mathew Barth, Robert Ferdman, Francisco J Hernandez-Ilizaliturri.
Curr Hematol Malig Rep, 2019 Sep 29; 14(5). PMID: 31559580
Review.
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IGFBP2 promotes immunosuppression associated with its mesenchymal induction and FcγRIIB phosphorylation in glioblastoma.
Yunmian Liu, Chunyan Song, +2 authors, Faping Shen, Jing Zhang, Sonya Wei Song. less
PLoS One, 2019 Sep 29; 14(9). PMID: 31560714 Free PMC article.
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Identification of key genes and pathways associated with different immune statuses of hepatitis B virus infection.
Jinglan Jin, Hongqin Xu, +4 authors, Ruihong Wu, Na Gao, Na Wu, Shibo Li, Junqi Niu. less
J Cell Mol Med, 2019 Oct 01; 23(11). PMID: 31565863 Free PMC article.
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Fcγ receptors and toll-like receptor 9 synergize to drive immune complex-induced dendritic cell maturation.
Nicole L J Nelson, Cheryl M Zajd, Michelle R Lennartz, Edmund J Gosselin.
Cell Immunol, 2019 Oct 05; 345. PMID: 31582169 Free PMC article.
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The Role of Immune Checkpoint Receptors in Regulating Immune Reactivity in Lupus.
Kun-Lin Lu, Ming-Ying Wu, +4 authors, Chi-Hui Wang, Chuang-Wei Wang, Shuen-Iu Hung, Wen-Hung Chung, Chun-Bing Chen. less
Cells, 2019 Oct 11; 8(10). PMID: 31597242 Free PMC article.
Review.
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Human Monoclonal Antibodies as Adjuvant Treatment of Chronic Hepatitis B Virus Infection.
Antonella Cerino, Stefania Mantovani, +3 authors, Dalila Mele, Barbara Oliviero, Stefania Varchetta, Mario U Mondelli. less
Front Immunol, 2019 Oct 15; 10. PMID: 31608071 Free PMC article.
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NK Cell-Fc Receptors Advance Tumor Immunotherapy.
Emilio Sanseviero.
J Clin Med, 2019 Oct 17; 8(10). PMID: 31614774 Free PMC article.
Review.
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Genetic Variation in Low-To-Medium-Affinity Fcγ Receptors: Functional Consequences, Disease Associations, and Opportunities for Personalized Medicine.
Sietse Q Nagelkerke, David E Schmidt, Masja de Haas, Taco W Kuijpers.
Front Immunol, 2019 Oct 22; 10. PMID: 31632391 Free PMC article.
Review.
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Tumor-binding antibodies induce potent dendritic cell-mediated tumor immunity.
Yaron Carmi, Tyler Prestwood, Edgar G Engleman.
Oncoimmunology, 2018 May 07; 8(10). PMID: 31646066 Free PMC article.
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The Complex Association of FcγRIIb With Autoimmune Susceptibility.
J Sjef Verbeek, Sachiko Hirose, Hiroyuki Nishimura.
Front Immunol, 2019 Nov 05; 10. PMID: 31681256 Free PMC article.
Review.
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Effect of Rhus verniciflua Extract on IgE-Antigen-Mediated Allergic Reaction in Rat Basophilic Leukemic RBL-2H3 Mast Cells and Passive Cutaneous Anaphylaxis in Mice.
Hyun Ju Do, Yeo Jin Hwang, Hye Jin Yang, Kwang Il Park.
Evid Based Complement Alternat Med, 2019 Nov 07; 2019. PMID: 31687037 Free PMC article.
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Proteoform-Resolved FcɤRIIIa Binding Assay for Fab Glycosylated Monoclonal Antibodies Achieved by Affinity Chromatography Mass Spectrometry of Fc Moieties.
Steffen Lippold, Simone Nicolardi, Manfred Wuhrer, David Falck.
Front Chem, 2019 Nov 12; 7. PMID: 31709228 Free PMC article.
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Boosting therapeutic potency of antibodies by taming Fc domain functions.
Tae Hyun Kang, Sang Taek Jung.
Exp Mol Med, 2019 Nov 19; 51(11). PMID: 31735912 Free PMC article.
Review.
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Impaired Antibody-Independent Immune Response of B Cells in Patients With Acute Dengue Infection.
Vinit Upasani, Hoa Thi My Vo, +9 authors, Sivlin Ung, Sothy Heng, Denis Laurent, Rithy Choeung, Veasna Duong, Sopheak Sorn, Sowath Ly, Izabela A Rodenhuis-Zybert, Philippe Dussart, Tineke Cantaert. less
Front Immunol, 2019 Nov 19; 10. PMID: 31736948 Free PMC article.
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Lupus-like Disease in FcγRIIB-/- Mice Induces Osteopenia.
Peerapat Visitchanakun, Worasit Saiworn, +3 authors, Prapaporn Jongwattanapisan, Asada Leelahavanichkul, Prapaporn Pisitkun, Sutada Lotinun. less
Sci Rep, 2019 Nov 24; 9(1). PMID: 31758072 Free PMC article.
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Differential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody-dependent (AD) NK cell activation and ADCC.
Irene Lisovsky, Sanket Kant, +8 authors, Alexandra Tremblay-McLean, Gamze Isitman, Zahra Kiani, Franck P Dupuy, Louise Gilbert, Julie Bruneau, Naglaa H Shoukry, Bertrand Lebouché, Nicole F Bernard. less
J Leukoc Biol, 2019 Jan 31; 105(3). PMID: 30698860 Free PMC article.
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Regulation of macrophage activity by surface receptors contained within Borrelia burgdorferi-enriched phagosomal fractions.
Ana Carreras-González, Diego Barriales, +18 authors, Ainhoa Palacios, Marta Montesinos-Robledo, Nicolás Navasa, Mikel Azkargorta, Ainize Peña-Cearra, Julen Tomás-Cortázar, Iraide Escobes, Miguel Angel Pascual-Itoiz, Jana Hradiská, Jan Kopecký, David Gil-Carton, Rafael Prados-Rosales, Leticia Abecia, Estíbaliz Atondo, Itziar Martín, Aize Pellón, Félix Elortza, Héctor Rodríguez, Juan Anguita. less
PLoS Pathog, 2019 Nov 19; 15(11). PMID: 31738806 Free PMC article.
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Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-μTP-L309C, a recombinant IgG1 Fc hexamer.
Bonnie J B Lewis, Jade Ville, +5 authors, Megan Blacquiere, Selena Cen, Rolf Spirig, Adrian W Zuercher, Fabian Käsermann, Donald R Branch. less
BMC Immunol, 2019 Dec 06; 20(1). PMID: 31801459 Free PMC article.
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Geometrical reorganization of Dectin-1 and TLR2 on single phagosomes alters their synergistic immune signaling.
Wenqian Li, Jun Yan, Yan Yu.
Proc Natl Acad Sci U S A, 2019 Nov 23; 116(50). PMID: 31754039 Free PMC article.
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Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor.
Chunshu Yang, Xiaoyu Hou, +4 authors, Qianhui Feng, Yingzhuo Li, Xuejiao Wang, Ling Qin, Pingting Yang. less
J Transl Med, 2019 Dec 23; 17(1). PMID: 31864410 Free PMC article.
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Harnessing MerTK agonism for targeted therapeutics.
Vivekananda Kedage, Diego Ellerman, +4 authors, Yongmei Chen, Wei-Ching Liang, Joven Borneo, Yan Wu, Minhong Yan. less
MAbs, 2019 Dec 20; 12(1). PMID: 31852344 Free PMC article.
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Desperately Seeking Therapies for Cerebral Malaria.
Brittany A Riggle, Louis H Miller, Susan K Pierce.
J Immunol, 2020 Jan 08; 204(2). PMID: 31907275 Free PMC article.
Review.
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Termination of immune activation: an essential component of healthy host immune responses.
Barry A Kane, Katherine J Bryant, H Patrick McNeil, Nicodemus T Tedla.
J Innate Immun, 2014 Jul 19; 6(6). PMID: 25033984 Free PMC article.
Review.
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IgA subclasses have different effector functions associated with distinct glycosylation profiles.
Ulrike Steffen, Carolien A Koeleman, +19 authors, Maria V Sokolova, Holger Bang, Arnd Kleyer, Jürgen Rech, Harald Unterweger, Martin Schicht, Fabian Garreis, Jonas Hahn, Fabian T Andes, Fabian Hartmann, Madelaine Hahn, Aparna Mahajan, Friedrich Paulsen, Markus Hoffmann, Günter Lochnit, Luis E Muñoz, Manfred Wuhrer, David Falck, Martin Herrmann, Georg Schett. less
Nat Commun, 2020 Jan 09; 11(1). PMID: 31913287 Free PMC article.
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Antibody-Dependent Cellular Cytotoxicity (ADCC)-Mediating Antibodies Constrain Neutralizing Antibody Escape Pathway.
Dieter Mielke, Gama Bandawe, +14 authors, Justin Pollara, Melissa-Rose Abrahams, Tinashe Nyanhete, Penny L Moore, Ruwayhida Thebus, Nicole L Yates, John C Kappes, Christina Ochsenbauer, Nigel Garrett, Salim Abdool Karim, Georgia D Tomaras, David Montefiori, Lynn Morris, Guido Ferrari, Carolyn Williamson. less
Front Immunol, 2020 Jan 11; 10. PMID: 31921139 Free PMC article.
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Update on Fc-Mediated Antibody Functions Against HIV-1 Beyond Neutralization.
Bin Su, Stefania Dispinseri, +6 authors, Valeria Iannone, Tong Zhang, Hao Wu, Raphael Carapito, Seiamak Bahram, Gabriella Scarlatti, Christiane Moog. less
Front Immunol, 2020 Jan 11; 10. PMID: 31921207 Free PMC article.
Review.
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Engineering the interactions between a plant-produced HIV antibody and human Fc receptors.
Szymon Stelter, Mathew J Paul, +7 authors, Audrey Y-H Teh, Melanie Grandits, Friedrich Altmann, Jessica Vanier, Muriel Bardor, Alexandra Castilho, Rachel Louise Allen, Julian K-C Ma. less
Plant Biotechnol J, 2019 Jul 14; 18(2). PMID: 31301102 Free PMC article.
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Fcγ Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita.
Balint Kovacs, Jenny Tillmann, +6 authors, Lisa-Christin Freund, Falk Nimmerjahn, Christian D Sadik, Katja Bieber, Ralf J Ludwig, Christian M Karsten, Jörg Köhl. less
Front Immunol, 2020 Jan 30; 10. PMID: 31993051 Free PMC article.
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Minimal B Cell Extrinsic IgG Glycan Modifications of Pro- and Anti-Inflammatory IgG Preparations in vivo.
Anja Schaffert, Maja Hanić, +10 authors, Mislav Novokmet, Olga Zaytseva, Jasminka Krištić, Anja Lux, Lars Nitschke, Matthias Peipp, Marija Pezer, René Hennig, Erdmann Rapp, Gordan Lauc, Falk Nimmerjahn. less
Front Immunol, 2020 Jan 31; 10. PMID: 31998308 Free PMC article.
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Phagocytosis checkpoints as new targets for cancer immunotherapy.
Mingye Feng, Wen Jiang, +3 authors, Betty Y S Kim, Cheng Cheng Zhang, Yang-Xin Fu, Irving L Weissman. less
Nat Rev Cancer, 2019 Aug 30; 19(10). PMID: 31462760 Free PMC article.
Highly Cited. Review.
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Receptor targeting drug delivery strategies and prospects in the treatment of rheumatoid arthritis.
Jaber Emami, Zahra Ansarypour.
Res Pharm Sci, 2020 Feb 11; 14(6). PMID: 32038727 Free PMC article.
Review.
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Factor VIII Fc Fusion Protein but not FVIII Drives Human Monocyte-Derived Dendritic Cell Activation via FcγRIIa.
Christoph Kannicht, Ilona Danßmann, +3 authors, Constanze Weilandt, Katja Derkow, Guido Kohla, Henriette Geyer. less
Hemasphere, 2020 Feb 20; 4(1). PMID: 32072146 Free PMC article.
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IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints.
Sudeepta Kumar Panda, Gustaf Wigerblad, +8 authors, Long Jiang, Yanek Jiménez-Andrade, Vaishnavi Srinivasan Iyer, Yunbing Shen, Sanjaykumar V Boddul, André Ortlieb Guerreiro-Cacais, Bruno Raposo, Zsolt Kasza, Fredrik Wermeling. less
Proc Natl Acad Sci U S A, 2020 Jan 26; 117(6). PMID: 31980518 Free PMC article.
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Predominant Role of Immunoglobulin G in the Pathogenesis of Splenomegaly in Murine Lupus.
Qian Zhang, Liping Xiang, +3 authors, Muhammad Haidar Zaman, Wenhui Dong, Guodan He, Guo-Min Deng. less
Front Immunol, 2020 Feb 23; 10. PMID: 32082297 Free PMC article.
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Elimination of activating Fcγ receptors in spontaneous autoimmune peripheral polyneuropathy model protects from neuropathic disease.
Gang Zhang, Nataliia Bogdanova, Tong Gao, Kazim A Sheikh.
PLoS One, 2019 Aug 16; 14(8). PMID: 31415574 Free PMC article.
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CEACAM3-A Prim(at)e Invention for Opsonin-Independent Phagocytosis of Bacteria.
Patrizia Bonsignore, Johannes W P Kuiper, +2 authors, Jonas Adrian, Griseldis Goob, Christof R Hauck. less
Front Immunol, 2020 Mar 03; 10. PMID: 32117212 Free PMC article.
Review.
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Recombinant Factor VIII Fc Inhibits B Cell Activation via Engagement of the FcγRIIB Receptor.
Maria T Georgescu, Paul C Moorehead, +4 authors, Tongyao Liu, Jennifer Dumont, David W Scott, Christine Hough, David Lillicrap. less
Front Immunol, 2020 Mar 03; 11. PMID: 32117285 Free PMC article.
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Probe Signal Values in mRNA Arrays Imply an Excessive Involvement of Neutrophil FCGR1 in Tuberculosis.
Kang Wu, Meng Li, +2 authors, Zhen-Yan Chen, Douglas B Lowrie, Xiao-Yong Fan. less
Front Med (Lausanne), 2020 Mar 03; 7. PMID: 32118006 Free PMC article.
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Tumour Necrosis Factor-α Inhibition Improves Stroke Outcome in a Mouse Model of Rheumatoid Arthritis.
N R Bonetti, C Diaz-Cañestro, +11 authors, L Liberale, M Crucet, A Akhmedov, M Merlini, M F Reiner, S Gobbato, S Stivala, G Kollias, F Ruschitzka, T F Lüscher, J H Beer, G G Camici. less
Sci Rep, 2019 Feb 20; 9(1). PMID: 30778120 Free PMC article.
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Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes.
Christian Rungsted Andersson, Jeppe Falsig, +5 authors, Jeffrey B Stavenhagen, Søren Christensen, Fredrik Kartberg, Nina Rosenqvist, Bente Finsen, Jan Torleif Pedersen. less
Sci Rep, 2019 Mar 16; 9(1). PMID: 30874605 Free PMC article.
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Patients with common variable immunodeficiency with autoimmune cytopenias exhibit hyperplastic yet inefficient germinal center responses.
Neil Romberg, Carole Le Coz, +17 authors, Salomé Glauzy, Jean-Nicolas Schickel, Melissa Trofa, Brian E Nolan, Michele Paessler, Mina L Xu, Michele P Lambert, Saquib A Lakhani, Mustafa K Khokha, Soma Jyonouchi, Jennifer Heimall, Patricia Takach, Paul J Maglione, Jason Catanzaro, F Ida Hsu, Kathleen E Sullivan, Charlotte Cunningham-Rundles, Eric Meffre. less
J Allergy Clin Immunol, 2018 Jun 24; 143(1). PMID: 29935219 Free PMC article.
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TLR9-mediated activation of dendritic cells by CD32 targeting for the generation of highly immunostimulatory vaccines.
J A Sepulveda-Toepfer, Johannes Pichler, +5 authors, Kathrin Fink, Milica Sevo, Sonja Wildburger, Liesbeth Christiene Mudde-Boer, Christopher Taus, Geert Cornelius Mudde. less
Hum Vaccin Immunother, 2018 Aug 30; 15(1). PMID: 30156957 Free PMC article.
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Humanised effector-null FcγRIIA antibody inhibits immune complex-mediated proinflammatory responses.
Bo Chen, Katherine A Vousden, +28 authors, Brian Naiman, Sean Turman, Hong Sun, Shu Wang, Lisa M K Vinall, Benjamin P Kemp, Srinath Kasturiangan, D Gareth Rees, Ethan Grant, Mary Jane Hinrichs, Steven Eck, Antonio DiGiandomenico, M Jack Borrok, Neang Ly, Ximing Xiong, Carlos Gonzalez, Christopher Morehouse, Yue Wang, Yebin Zhou, Jennifer Cann, Weiguang Zhao, Holly Koelkebeck, Koshu Okubo, Tanya N Mayadas, David Howe, Janet Griffiths, Roland Kolbeck, Ronald Herbst, Gary P Sims. less
Ann Rheum Dis, 2018 Nov 22; 78(2). PMID: 30459279 Free PMC article.
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OMIP-051 - 28-color flow cytometry panel to characterize B cells and myeloid cells.
Thomas Liechti, Mario Roederer.
Cytometry A, 2018 Dec 15; 95(2). PMID: 30549419 Free PMC article.
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CD32 Ligation Promotes the Activation of CD4+ T Cells.
María Pía Holgado, Inés Sananez, +2 authors, Silvina Raiden, Jorge R Geffner, Lourdes Arruvito. less
Front Immunol, 2018 Dec 18; 9. PMID: 30555482 Free PMC article.
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The genomic organization and expression pattern of the low-affinity Fc gamma receptors (FcγR) in the Göttingen minipig.
Jerome Egli, Roland Schmucki, +6 authors, Benjamin Loos, Stephan Reichl, Nils Grabole, Andreas Roller, Martin Ebeling, Alex Odermatt, Antonio Iglesias. less
Immunogenetics, 2018 Dec 20; 71(2). PMID: 30564855 Free PMC article.
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AS03-Adjuvanted H5N1 Avian Influenza Vaccine Modulates Early Innate Immune Signatures in Human Peripheral Blood Mononuclear Cells.
Leigh M Howard, Johannes B Goll, +8 authors, Travis L Jensen, Kristen L Hoek, Nripesh Prasad, Casey E Gelber, Shawn E Levy, Sebastian Joyce, Andrew J Link, C Buddy Creech, Kathryn M Edwards. less
J Infect Dis, 2018 Dec 20; 219(11). PMID: 30566602 Free PMC article.
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Expression of a Recombinant High Affinity IgG Fc Receptor by Engineered NK Cells as a Docking Platform for Therapeutic mAbs to Target Cancer Cells.
Kristin M Snyder, Robert Hullsiek, +6 authors, Hemant K Mishra, Daniel C Mendez, Yunfang Li, Allison Rogich, Dan S Kaufman, Jianming Wu, Bruce Walcheck. less
Front Immunol, 2018 Dec 24; 9. PMID: 30574146 Free PMC article.
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Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody.
Danbee Ha, Atsushi Tanaka, +10 authors, Tatsuya Kibayashi, Atsushi Tanemura, Daisuke Sugiyama, James Badger Wing, Ee Lyn Lim, Karen Wei Weng Teng, Dennis Adeegbe, Evan W Newell, Ichiro Katayama, Hiroyoshi Nishikawa, Shimon Sakaguchi. less
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Lupus-Associated Immune Complexes Activate Human Neutrophils in an FcγRIIA-Dependent but TLR-Independent Response.
Ramon G Bonegio, Jessica D Lin, +3 authors, Britte Beaudette-Zlatanova, Michael R York, Hanni Menn-Josephy, Kei Yasuda. less
J Immunol, 2019 Jan 06; 202(3). PMID: 30610165 Free PMC article.
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Human neutrophils express low levels of FcγRIIIA, which plays a role in PMN activation.
Josée Golay, Rut Valgardsdottir, +3 authors, Gerta Musaraj, Damiano Giupponi, Orietta Spinelli, Martino Introna. less
Blood, 2019 Jan 19; 133(13). PMID: 30655272 Free PMC article.
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Multi-isotype Glycoproteomic Characterization of Serum Antibody Heavy Chains Reveals Isotype- and Subclass-Specific N-Glycosylation Profiles.
Kevin Brown Chandler, Nickita Mehta, +3 authors, Deborah R Leon, Todd J Suscovich, Galit Alter, Catherine E Costello. less
Mol Cell Proteomics, 2019 Jan 20; 18(4). PMID: 30659065 Free PMC article.
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Fc gamma RIIb expression levels in human liver sinusoidal endothelial cells during progression of non-alcoholic fatty liver disease.
Tomoko Ishikawa, Hiroshi Yokoyama, Tomokazu Matsuura, Yoko Fujiwara.
PLoS One, 2019 Jan 30; 14(1). PMID: 30695042 Free PMC article.
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The Impact of FcγRI Binding on Immuno-PET.
Delphine Vivier, Sai Kiran Sharma, +3 authors, Pierre Adumeau, Cindy Rodriguez, Kimberly Fung, Brian M Zeglis. less
J Nucl Med, 2019 Feb 09; 60(8). PMID: 30733320 Free PMC article.
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Current Strategies to Inhibit High Affinity FcεRI-Mediated Signaling for the Treatment of Allergic Disease.
Gregorio Gomez.
Front Immunol, 2019 Feb 23; 10. PMID: 30792720 Free PMC article.
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Bridging Vaccine-Induced HIV-1 Neutralizing and Effector Antibody Responses in Rabbit and Rhesus Macaque Animal Models.
Justin Pollara, Dorothy I Jones, +14 authors, Tori Huffman, R Whitney Edwards, Maria Dennis, Shuk Hang Li, Shalini Jha, Derrick Goodman, Amit Kumar, Celia C LaBranche, David C Montefiori, Genevieve G Fouda, Thomas J Hope, Georgia D Tomaras, Herman F Staats, Guido Ferrari, Sallie R Permar. less
J Virol, 2019 Mar 08; 93(10). PMID: 30842326 Free PMC article.
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Infection-Induced Resistance to Experimental Cerebral Malaria Is Dependent Upon Secreted Antibody-Mediated Inhibition of Pathogenic CD8+ T Cell Responses.
Tovah N Shaw, Colette A Inkson, +6 authors, Ana Villegas-Mendez, David J Pattinson, Patrick Strangward, Kathryn J Else, Simon J Draper, Leo A H Zeef, Kevin N Couper. less
Front Immunol, 2019 Mar 09; 10. PMID: 30846985 Free PMC article.
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Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.
Tomas Castro-Dopico, Thomas W Dennison, +13 authors, John R Ferdinand, Rebeccah J Mathews, Aaron Fleming, Dean Clift, Benjamin J Stewart, Chenzhi Jing, Konstantina Strongili, Larisa I Labzin, Edward J M Monk, Kourosh Saeb-Parsy, Clare E Bryant, Simon Clare, Miles Parkes, Menna R Clatworthy. less
Immunity, 2019 Mar 17; 50(4). PMID: 30876876 Free PMC article.
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Integrin β1 Promotes the Interaction of Murine IgG3 with Effector Cells.
Carolyn Saylor Hawk, Carolina Coelho, +11 authors, Diane Sthefany Lima de Oliveira, Verenice Paredes, Patrícia Albuquerque, Anamélia Lorenzetti Bocca, Ananésia Correa Dos Santos, Victoria Rusakova, Heather Holemon, Ildinete Silva-Pereira, Maria Sueli Soares Felipe, Hideo Yagita, André Moraes Nicola, Arturo Casadevall. less
J Immunol, 2019 Mar 22; 202(9). PMID: 30894426 Free PMC article.
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Important roles of CD32 in promoting suppression of IL-4 induced immune responses by a novel anti-IL-4Rα therapeutic antibody.
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MAbs, 2019 Apr 06; 11(5). PMID: 30950681 Free PMC article.
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Contribution of Fcγ Receptor-Mediated Immunity to the Pathogenesis Caused by the Human Respiratory Syncytial Virus.
Orlando A Acevedo, Fabián E Díaz, +5 authors, Tomas E Beals, Felipe M Benavente, Jorge A Soto, Jorge Escobar-Vera, Pablo A González, Alexis M Kalergis. less
Front Cell Infect Microbiol, 2019 Apr 16; 9. PMID: 30984626 Free PMC article.
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Systems serology for decoding infection and vaccine-induced antibody responses to HIV-1.
Srivamshi Pittala, Kyle S Morrison, Margaret E Ackerman.
Curr Opin HIV AIDS, 2019 Apr 30; 14(4). PMID: 31033729 Free PMC article.
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Fc-Fusion Drugs Have FcγR/C1q Binding and Signaling Properties That May Affect Their Immunogenicity.
H A Daniel Lagassé, Hartmut Hengel, Basil Golding, Zuben E Sauna.
AAPS J, 2019 May 08; 21(4). PMID: 31062128
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B Cell Fcγ Receptor IIb Modulates Atherosclerosis in Male and Female Mice by Controlling Adaptive Germinal Center and Innate B-1-Cell Responses.
Jayashree Bagchi-Chakraborty, Anna Francis, +12 authors, Toni Bray, Leanne Masters, Dimitrios Tsiantoulas, Meritxell Nus, James Harrison, Michelle Broekhuizen, Jennifer Leggat, Menna R Clatworthy, Marion Espéli, Kenneth G C Smith, Christoph J Binder, Ziad Mallat, Andrew P Sage. less
Arterioscler Thromb Vasc Biol, 2019 May 17; 39(7). PMID: 31092015 Free PMC article.
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Optimization of 4-1BB antibody for cancer immunotherapy by balancing agonistic strength with FcγR affinity.
Xinyue Qi, Fanlin Li, +4 authors, Yi Wu, Chen Cheng, Ping Han, Jieyi Wang, Xuanming Yang. less
Nat Commun, 2019 May 21; 10(1). PMID: 31105267 Free PMC article.
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Combinatorial diversity of Syk recruitment driven by its multivalent engagement with FcεRIγ.
Timothy Travers, William K Kanagy, +6 authors, Rachael A Mansbach, Elton Jhamba, Cedric Cleyrat, Byron Goldstein, Diane S Lidke, Bridget S Wilson, S Gnanakaran. less
Mol Biol Cell, 2019 Jun 20; 30(17). PMID: 31216232 Free PMC article.
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NK cell-intrinsic FcεRIγ limits CD8+ T-cell expansion and thereby turns an acute into a chronic viral infection.
Vikas Duhan, Thamer A Hamdan, +10 authors, Haifeng C Xu, Prashant Shinde, Hilal Bhat, Fanghui Li, Yahya Al-Matary, Dieter Häussinger, Judith Bezgovsek, Sarah-Kim Friedrich, Cornelia Hardt, Philipp A Lang, Karl S Lang. less
PLoS Pathog, 2019 Jun 21; 15(6). PMID: 31220194 Free PMC article.
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C-reactive protein (CRP) promotes malignant properties in pancreatic neuroendocrine neoplasms.
Simon Schimmack, Yongchao Yang, +6 authors, Klaus Felix, Markus Herbst, Yixiong Li, Miriam Schenk, Frank Bergmann, Thilo Hackert, Oliver Strobel. less
Endocr Connect, 2019 Jun 25; 8(7). PMID: 31234146 Free PMC article.
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Zika Virus-Immune Plasmas from Symptomatic and Asymptomatic Individuals Enhance Zika Pathogenesis in Adult and Pregnant Mice.
Byoung-Shik Shim, Young-Chan Kwon, +13 authors, Michael J Ricciardi, Mars Stone, Yuka Otsuka, Fatma Berri, Jaclyn M Kwal, Diogo M Magnani, Cody B Jackson, Audrey S Richard, Philip Norris, Michael Busch, Christine L Curry, Michael Farzan, David Watkins, Hyeryun Choe. less
mBio, 2019 Jul 04; 10(4). PMID: 31266863 Free PMC article.
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Transient and chronic childhood immune thrombocytopenia are distinctly affected by Fc-γ receptor polymorphisms.
David E Schmidt, Katja M J Heitink-Pollé, +8 authors, Annemieke G Laarhoven, Marrie C A Bruin, Barbera Veldhuisen, Sietse Q Nagelkerke, Taco W Kuijpers, Leendert Porcelijn, C Ellen van der Schoot, Gestur Vidarsson, Masja de Haas. less
Blood Adv, 2019 Jul 05; 3(13). PMID: 31270082 Free PMC article.
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Glycoform-resolved FcɣRIIIa affinity chromatography-mass spectrometry.
Steffen Lippold, Simone Nicolardi, +6 authors, Elena Domínguez-Vega, Anna-Katharina Heidenreich, Gestur Vidarsson, Dietmar Reusch, Markus Haberger, Manfred Wuhrer, David Falck. less
MAbs, 2019 Jul 06; 11(7). PMID: 31276431 Free PMC article.
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Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor.
Xiaoyang Liu, Senthilkumar Palaniyandi, +7 authors, Iowis Zhu, Jin Tang, Weizhong Li, Xiaoling Wu, Susan Park Ochsner, C David Pauza, Jeffrey I Cohen, Xiaoping Zhu. less
Nat Commun, 2019 Jul 11; 10(1). PMID: 31289263 Free PMC article.
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IFN-mediated negative feedback supports bacteria class-specific macrophage inflammatory responses.
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Elife, 2019 Aug 07; 8. PMID: 31385572 Free PMC article.
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TRIM21-From Intracellular Immunity to Therapy.
Stian Foss, Maria Bottermann, +3 authors, Alexandra Jonsson, Inger Sandlie, Leo C James, Jan Terje Andersen. less
Front Immunol, 2019 Sep 27; 10. PMID: 31555278 Free PMC article.
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Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology.
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EMBO Mol Med, 2020 Jan 18; 12(3). PMID: 31951107 Free PMC article.
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Fc Glycan-Mediated Regulation of Placental Antibody Transfer.
Madeleine F Jennewein, Ilona Goldfarb, +20 authors, Sepideh Dolatshahi, Cormac Cosgrove, Francesca J Noelette, Marina Krykbaeva, Jishnu Das, Aniruddh Sarkar, Matthew J Gorman, Stephanie Fischinger, Carolyn M Boudreau, Joelle Brown, Jennifer H Cooperrider, Jasneet Aneja, Todd J Suscovich, Barney S Graham, Georg M Lauer, Tessa Goetghebuer, Arnaud Marchant, Douglas Lauffenburger, Arthur Y Kim, Laura E Riley, Galit Alter. less
Cell, 2019 Jun 18; 178(1). PMID: 31204102 Free PMC article.
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Boosting of Markers of Fcγ Receptor Function in Anti-HIV Antibodies During Structured Treatment Interruption.
Hugh Billings, Bruce D Wines, +4 authors, Wayne B Dyer, Robert J Center, Halina M Trist, Stephen J Kent, P Mark Hogarth. less
AIDS Res Hum Retroviruses, 2019 Jul 11; 35(9). PMID: 31288562 Free PMC article.
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Antibody-Mediated Porcine Reproductive and Respiratory Syndrome Virus Infection Downregulates the Production of Interferon-α and Tumor Necrosis Factor-α in Porcine Alveolar Macrophages via Fc Gamma Receptor I and III.
Liujun Zhang, Wen Li, +4 authors, Yangyang Sun, Linghao Kong, Pengli Xu, Pingan Xia, Gaiping Zhang. less
Viruses, 2020 Feb 13; 12(2). PMID: 32046249 Free PMC article.
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Fc-Linked IgG N-Glycosylation in FcγR Knock-Out Mice.
Olga O Zaytseva, Michaela Seeling, +3 authors, Jasminka Krištić, Gordan Lauc, Marija Pezer, Falk Nimmerjahn. less
Front Cell Dev Biol, 2020 Mar 21; 8. PMID: 32195245 Free PMC article.
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High-resolution quantification of discrete phagocytic events by live cell time-lapse high-content microscopy imaging.
Charles C Chu, Jonathan J Pinney, +4 authors, Hannah E Whitehead, Fatima Rivera-Escalera, Karl R VanDerMeid, Clive S Zent, Michael R Elliott. less
J Cell Sci, 2020 Feb 02; 133(5). PMID: 32005699 Free PMC article.
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Monocyte procoagulant responses to anthrax peptidoglycan are reinforced by proinflammatory cytokine signaling.
Narcis Ioan Popescu, Alanson Girton, +2 authors, Tarea Burgett, Kessa Lovelady, K Mark Coggeshall. less
Blood Adv, 2019 Aug 17; 3(16). PMID: 31416821 Free PMC article.
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Therapeutic use of immunoglobulins.
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The Role of Complement in Transfusion-Related Acute Lung Injury.
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Impact of Human FcγR Gene Polymorphisms on IgG-Triggered Cytokine Release: Critical Importance of Cell Assay Format.
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Evaluation of in vitro Assays to Assess the Modulation of Dendritic Cells Functions by Therapeutic Antibodies and Aggregates.
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PD-1 Primarily Targets TCR Signal in the Inhibition of Functional T Cell Activation.
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Exploring the Immunological Mechanisms Underlying the Anti-vascular Endothelial Growth Factor Activity in Tumors.
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Antibody-Dependent Cellular Phagocytosis in Antiviral Immune Responses.
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Front Immunol, 2019 Mar 16; 10. PMID: 30873178 Free PMC article.
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DecoyDeveloper: An On-Demand, De Novo Decoy Glycopeptide Generator.
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The Human FcγRII (CD32) Family of Leukocyte FcR in Health and Disease.
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An Engineered Human Fc variant With Exquisite Selectivity for FcγRIIIaV158 Reveals That Ligation of FcγRIIIa Mediates Potent Antibody Dependent Cellular Phagocytosis With GM-CSF-Differentiated Macrophages.
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Current Concepts on 6-sulfo LacNAc Expressing Monocytes (slanMo).
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FcγR-Binding Is an Important Functional Attribute for Immune Checkpoint Antibodies in Cancer Immunotherapy.
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Front Immunol, 2019 Mar 14; 10. PMID: 30863404 Free PMC article.
Highly Cited. Review.
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Molecular Insights Into the Relationship Between Autoimmune Thyroid Diseases and Breast Cancer: A Critical Perspective on Autoimmunity and ER Stress.
Safikur Rahman, Ayyagari Archana, +4 authors, Arif Tasleem Jan, Durgashree Dutta, Abhishek Shankar, Jihoe Kim, Rinki Minakshi. less
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Mind the Gap: How Interspecies Variability in IgG and Its Receptors May Complicate Comparisons of Human and Non-human Primate Effector Function.
Andrew R Crowley, Margaret E Ackerman.
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Chronic HIV-1 Infection Alters the Cellular Distribution of FcγRIIIa and the Functional Consequence of the FcγRIIIa-F158V Variant.
Ntando G Phaahla, Ria Lassaunière, +3 authors, Bianca Da Costa Dias, Ziyaad Waja, Neil A Martinson, Caroline T Tiemessen. less
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FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming.
Willianne Hoepel, Melissa Newling, +6 authors, Lisa T C Vogelpoel, Lathees Sritharan, Ivo S Hansen, Martien L Kapsenberg, Dominique L P Baeten, Bart Everts, Jeroen den Dunnen. less
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IgG and Fcγ Receptors in Intestinal Immunity and Inflammation.
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Knowns and Unknowns of Assaying Antibody-Dependent Cell-Mediated Cytotoxicity Against HIV-1.
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Expression, Role, and Regulation of Neutrophil Fcγ Receptors.
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A Sample-Sparing Multiplexed ADCP Assay.
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Influenza and Antibody-Dependent Cellular Cytotoxicity.
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Review.
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Immunoglobulin Therapy in a Patient With Severe Chikungunya Fever and Vesiculobullous Lesions.
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How Autoantibodies Regulate Osteoclast Induced Bone Loss in Rheumatoid Arthritis.
Ulrike Steffen, Georg Schett, Aline Bozec.
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Review.
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Targeting Conventional Dendritic Cells to Fine-Tune Antibody Responses.
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Alveolar Macrophage Dysfunction and Increased PD-1 Expression During Chronic SIV Infection of Rhesus Macaques.
Ruth Hunegnaw, Zuena Mushtaq, +2 authors, Gospel Enyindah-Asonye, Tanya Hoang, Marjorie Robert-Guroff. less
Front Immunol, 2019 Jul 25; 10. PMID: 31333668 Free PMC article.
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Influenza A Virus Antibodies with Antibody-Dependent Cellular Cytotoxicity Function.
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Interaction analysis of glycoengineered antibodies with CD16a: a native mass spectrometry approach.
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Fc receptors in antibody-dependent enhancement of viral infections.
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Kawasaki Disease: The Role of Immune Complexes Revisited.
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The Diverse Functions of the Ubiquitous Fcγ Receptors and Their Unique Constituent, FcRγ Subunit.
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Immunomodulation in Primary Immune Thrombocytopenia: A Possible Role of the Fc Fragment of Romiplostim?
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Conceptual Approaches to Modulating Antibody Effector Functions and Circulation Half-Life.
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Highly Cited. Review.
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Lactoferrin-containing immunocomplex mediates antitumor effects by resetting tumor-associated macrophages to M1 phenotype.
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Reprogramming the Constant Region of Immunoglobulin G Subclasses for Enhanced Therapeutic Potency against Cancer.
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A new cell line for assessing HIV-1 antibody dependent cellular cytotoxicity against a broad range of variants.
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Dual transcriptomic and epigenomic study of reaction severity in peanut-allergic children.
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The trinity of COVID-19: immunity, inflammation and intervention.
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Understanding SARS-CoV-2-Mediated Inflammatory Responses: From Mechanisms to Potential Therapeutic Tools.
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Differential immunoglobulin and complement levels in leprosy prior to development of reversal reaction and erythema nodosum leprosum.
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A classical swine fever virus E2 fusion protein produced in plants elicits a neutralizing humoral immune response in mice and pigs.
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Passive Immunotherapies for Central Nervous System Disorders: Current Delivery Challenges and New Approaches.
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FcγR Binding and ADCC Activity of Human IgG Allotypes.
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Isotype Switching Converts Anti-CD40 Antagonism to Agonism to Elicit Potent Antitumor Activity.
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HIV infection drives IgM and IgG3 subclass bias in Plasmodium falciparum-specific and total immunoglobulin concentration in Western Kenya.
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CARs: Beyond T Cells and T Cell-Derived Signaling Domains.
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Exploring pharmacological approaches for managing cytokine storm associated with pneumonia and acute respiratory distress syndrome in COVID-19 patients.
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A cross-reactive mouse monoclonal antibody against rhinovirus mediates phagocytosis in vitro.
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Sci Rep, 2020 Jun 18; 10(1). PMID: 32546721 Free PMC article.
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Looking for the Optimal PD-1/PD-L1 Inhibitor in Cancer Treatment: A Comparison in Basic Structure, Function, and Clinical Practice.
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Opsonization-Enhanced Antigen Presentation by MR1 Activates Rapid Polyfunctional MAIT Cell Responses Acting as an Effector Arm of Humoral Antibacterial Immunity.
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Fc Gamma Receptors and Complement Component 3 Facilitate Anti-fVIII Antibody Formation.
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Signaling through the Inhibitory Fc Receptor FcγRIIB Induces CD8+ T Cell Apoptosis to Limit T Cell Immunity.
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Endoglycosidases for the Synthesis of Polysaccharides and Glycoconjugates.
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Differential Role for Activating FcγRIII in Neointima Formation After Arterial Injury and Diet-Induced Chronic Atherosclerosis in Apolipoprotein E-Deficient Mice.
Yaw Asare, Janine Koehncke, +6 authors, Jaco Selle, Sakine Simsekyilmaz, Joachim Jankowski, Gansuvd Shagdarsuren, Johannes E Gessner, Jürgen Bernhagen, Erdenechimeg Shagdarsuren. less
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The neonatal Fc receptor in cancer FcRn in cancer.
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Spatiotemporal immune zonation of the human kidney.
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Development of a VLP-Based Vaccine Displaying an xCT Extracellular Domain for the Treatment of Metastatic Breast Cancer.
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Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis.
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Novel genetic variants in genes of the Fc gamma receptor-mediated phagocytosis pathway predict non-small cell lung cancer survival.
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FcgRIII Deficiency and FcgRIIb Defeciency Promote Renal Injury in Diabetic Mice.
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Role of Opsonophagocytosis in Immune Protection against Malaria.
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A single-cell atlas of the peripheral immune response in patients with severe COVID-19.
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Memory T cell-mediated rejection is mitigated by FcγRIIB expression on CD8+ T cells.
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A fentanyl vaccine constructed upon opsonizing antibodies specific for the Galα1-3Gal epitope.
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Neuroinflammation in dementia with Lewy bodies: a human post-mortem study.
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Human Fcγ-receptor IIb modulates pathogen-specific versus self-reactive antibody responses in lyme arthritis.
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Sialylated Immunoglobulins for the Treatment of Immuno-Inflammatory Diseases.
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Harnessing the Complete Repertoire of Conventional Dendritic Cell Functions for Cancer Immunotherapy.
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Preferential Presentation of High-Affinity Immune Complexes in Germinal Centers Can Explain How Passive Immunization Improves the Humoral Response.
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A Plant-Derived Antigen-Antibody Complex Induces Anti-Cancer Immune Responses by Forming a Large Quaternary Structure.
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Structural insights into the mechanisms and specificities of IgG-active endoglycosidases.
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Targeting the blood-nerve barrier for the management of immune-mediated peripheral neuropathies.
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The Role of IgG Subclass in Antibody-Mediated Protection against Carbapenem-Resistant Klebsiella pneumoniae.
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MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N-Glycosylation.
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Antibody immunoglobulin G1 and immunoglobulin G2a responses against some cystic fluid proteins of Cysticercus bovis in Balb/c mice.
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Heat-Killed Saccharomyces cerevisiae, A Dectin-1 Agonist, Selectively Induces IgG4 Production by Human B Cells.
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Epidermolysis Bullosa Acquisita: The 2019 Update.
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Use of Dendritic Cell Receptors as Targets for Enhancing Anti-Cancer Immune Responses.
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Liposomal Fc Domain Conjugated to a Cancer Vaccine Enhances Both Humoral and Cellular Immunity.
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ACS Omega, 2019 Apr 06; 4(3). PMID: 30949616 Free PMC article.
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Commentary: Fc Gamma Receptors are Expressed in the Developing Rat Brain and Activate Downstream Signaling Molecules upon Cross-Linking with Immune Complex.
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J Neurol Neuromedicine, 2019 May 28; 4(1). PMID: 31131371 Free PMC article.
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Single-Domain Antibodies and Their Formatting to Combat Viral Infections.
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Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.
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Neurological Complications Associated with the Blood-Brain Barrier Damage Induced by the Inflammatory Response During SARS-CoV-2 Infection.
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Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain.
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Site-Specific Glycosylation Mapping of Fc Gamma Receptor IIIb from Neutrophils of Individual Healthy Donors.
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A versatile soluble siglec scaffold for sensitive and quantitative detection of glycan ligands.
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SARS-CoV-2 mediated lung inflammatory responses in host: targeting the cytokine storm for therapeutic interventions.
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Kinase inhibition in autoimmunity and inflammation.
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Contributions of Major Cell Populations to Sjögren's Syndrome.
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Acquired antibody responses against merozoite surface protein-119 antigen during Plasmodium falciparum and P.vivax infections in South Indian city of Mangaluru.
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Aglycosylated antibody-producing mice for aglycosylated antibody-lectin coupled immunoassay for the quantification of tumor markers (ALIQUAT).
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Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer's disease.
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Intratumoral injection reduces toxicity and antibody-mediated neutralization of immunocytokine in a mouse melanoma model.
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Identification of "antigen-specific" neutrophils in atherosclerosis patients that compromise vascular endothelial barrier function.
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Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality.
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RBD-Fc-based COVID-19 vaccine candidate induces highly potent SARS-CoV-2 neutralizing antibody response.
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Activation of Macrophages by Oligomeric Proteins of Different Size and Origin.
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The Binding of Human IgG to Minipig FcγRs - Implications for Preclinical Assessment of Therapeutic Antibodies.
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Differences of the Structure of Immune Regulatory Cell Populations between Cellular Material from Sonographically Detected Focal Thyroid Lesions and Peripheral Blood in Humans.
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Impact of CD14 on Reactive Oxygen Species Production from Human Leukocytes Primed by Escherichia coli Lipopolysaccharides.
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Vaccination with a chikungunya virus-like particle vaccine exacerbates disease in aged mice.
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Intercellular wireless communication network between mother and fetus in rat pregnancy-a study on directed and weighted network.
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Soluble fibrinogen-like protein 2 promotes the growth of hepatocellular carcinoma via attenuating dendritic cell-mediated cytotoxic T cell activity.
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Fc-Engineering for Modulated Effector Functions-Improving Antibodies for Cancer Treatment.
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Functional Domain Order of an Anti-EGFR × Anti-CD16 Bispecific Diabody Involving NK Cell Activation.
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Why remission is not enough: underlying disease mechanisms in RA that prevent cure.
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An Anti-MICA/B Antibody and IL-15 Rescue Altered NKG2D-Dependent NK Cell Responses in Hepatocellular Carcinoma.
Stefania Mantovani, Stefania Varchetta, +19 authors, Dalila Mele, Matteo Donadon, Guido Torzilli, Cristiana Soldani, Barbara Franceschini, Camillo Porta, Silvia Chiellino, Paolo Pedrazzoli, Roberto Santambrogio, Matteo Barabino, Claudia Cigala, Gaetano Piccolo, Enrico Opocher, Marcello Maestri, Angelo Sangiovanni, Stefano Bernuzzi, Florence Lhospice, Manel Kraiem, Mario Umberto Mondelli, Barbara Oliviero. less
Cancers (Basel), 2020 Dec 04; 12(12). PMID: 33266137 Free PMC article.
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IgE and IgG Antibodies as Regulators of Mast Cell and Basophil Functions in Food Allergy.
Cynthia Kanagaratham, Yasmeen S El Ansari, Owen L Lewis, Hans C Oettgen.
Front Immunol, 2020 Dec 29; 11. PMID: 33362785 Free PMC article.
Review.
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The Multiple Functions of B Cells in Chronic HBV Infection.
Ying Cai, Wenwei Yin.
Front Immunol, 2021 Jan 01; 11. PMID: 33381113 Free PMC article.
Review.
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TRIGGERED: could refocused cell signaling be key to natural killer cell-based HIV immunotherapeutics?
Sho Sugawara, Cordelia Manickam, R Keith Reeves.
AIDS, 2020 Oct 30; 35(2). PMID: 33116071 Free PMC article.
Review.
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The Current Landscape of Antibody-based Therapies in Solid Malignancies.
Ashu Shah, Sanchita Rauth, +6 authors, Abhijit Aithal, Sukhwinder Kaur, Koelina Ganguly, Catherine Orzechowski, Grish C Varshney, Maneesh Jain, Surinder K Batra. less
Theranostics, 2021 Jan 05; 11(3). PMID: 33391547 Free PMC article.
Review.
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COVID-19: inflammatory responses, structure-based drug design and potential therapeutics.
Neetu Tripathi, Neeraj Tripathi, Manoj Kumar Goshisht.
Mol Divers, 2021 Jan 06; 26(1). PMID: 33400086 Free PMC article.
Review.
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FcγRIIb differentially regulates pre-immune and germinal center B cell tolerance in mouse and human.
Marion Espéli, Rachael Bashford-Rogers, +5 authors, John M Sowerby, Nagham Alouche, Limy Wong, Alice E Denton, Michelle A Linterman, Kenneth G C Smith. less
Nat Commun, 2019 May 01; 10(1). PMID: 31036800 Free PMC article.
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A quantitative Streptococcus pyogenes-human protein-protein interaction map reveals localization of opsonizing antibodies.
Lotta Happonen, Simon Hauri, +9 authors, Gabriel Svensson Birkedal, Christofer Karlsson, Therese de Neergaard, Hamed Khakzad, Pontus Nordenfelt, Mats Wikström, Magdalena Wisniewska, Lars Björck, Lars Malmström, Johan Malmström. less
Nat Commun, 2019 Jun 23; 10(1). PMID: 31227708 Free PMC article.
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Dysregulation of hepatic microRNA expression in C57BL/6 mice affected by excretory-secretory products of Fasciola gigantica.
Wei Shi, Jun-Jun He, +7 authors, Xue-Fang Mei, Ke-Jing Lu, Zi-Xuan Zeng, Yao-Yao Zhang, Zhao-An Sheng, Hany M Elsheikha, Wei-Yi Huang, Xing-Quan Zhu. less
PLoS Negl Trop Dis, 2020 Dec 18; 14(12). PMID: 33332355 Free PMC article.
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A proteomics-based method for identifying antigens within immune complexes.
Stephanie Menikou, Andrew J McArdle, +3 authors, Ming-Shi Li, Myrsini Kaforou, Paul R Langford, Michael Levin. less
PLoS One, 2020 Dec 29; 15(12). PMID: 33362259 Free PMC article.
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A recombinant protein SARS-CoV-2 candidate vaccine elicits high-titer neutralizing antibodies in macaques.
Gary Baisa, David Rancour, +9 authors, Keith Mansfield, Monika Burns, Lori Martin, Daise Cunha, Jessica Fischer, Frauke Muecksch, Theodora Hatziioannou, Paul Bieniasz, Frtiz Schomburg, Kimberly Luke. less
bioRxiv, 2021 Jan 06;. PMID: 33398285 Free PMC article.
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Inhibition of B cell activation following in vivo co-engagement of B cell antigen receptor and Fcγ receptor IIb in non-autoimmune-prone and SLE-prone mice.
Seung Y Chu, Erik Pong, +6 authors, Christine Bonzon, Ning Yu, Chaim O Jacob, Samantha A Chalmers, Chaim Putterman, David E Szymkowski, William Stohl. less
J Transl Autoimmun, 2021 Jan 08; 4. PMID: 33409482 Free PMC article.
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Gene Expression Analysis of the Pre-Diabetic Pancreas to Identify Pathogenic Mechanisms and Biomarkers of Type 1 Diabetes.
Linda Yip, Rebecca Fuhlbrigge, Reem Alkhataybeh, C Garrison Fathman.
Front Endocrinol (Lausanne), 2021 Jan 12; 11. PMID: 33424774 Free PMC article.
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A Recombinant Protein SARS-CoV-2 Candidate Vaccine Elicits High-titer Neutralizing Antibodies in Macaques.
Gary Baisa, David Rancour, +9 authors, Keith Mansfield, Monika Burns, Lori Martin, Daise Cunha, Jessica Fischer, Frauke Muecksch, Theodora Hatziioannou, Paul D Bieniasz, Fritz Schomburg, Kimberly Luke. less
Res Sq, 2021 Jan 15;. PMID: 33442678 Free PMC article.
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Therapeutic targeting of TGF-β in cancer: hacking a master switch of immune suppression.
Jitske van den Bulk, Noel F C C de Miranda, Peter Ten Dijke.
Clin Sci (Lond), 2021 Jan 06; 135(1). PMID: 33399850 Free PMC article.
Review.
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Intravenous Immunoglobulins at the Crossroad of Autoimmunity and Viral Infections.
Carlo Perricone, Paola Triggianese, +5 authors, Roberto Bursi, Giacomo Cafaro, Elena Bartoloni, Maria Sole Chimenti, Roberto Gerli, Roberto Perricone. less
Microorganisms, 2021 Jan 13; 9(1). PMID: 33430200 Free PMC article.
Review.
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ADCC against MICA/B Is Mediated against Differentiated Oral and Pancreatic and Not Stem-Like/Poorly Differentiated Tumors by the NK Cells; Loss in Cancer Patients due to Down-Modulation of CD16 Receptor.
Kawaljit Kaur, Tahmineh Safaie, +2 authors, Meng-Wei Ko, Yuhao Wang, Anahid Jewett. less
Cancers (Basel), 2021 Jan 15; 13(2). PMID: 33440654 Free PMC article.
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Engineering Anti-Tumor Monoclonal Antibodies and Fc Receptors to Enhance ADCC by Human NK Cells.
Kate J Dixon, Jianming Wu, Bruce Walcheck.
Cancers (Basel), 2021 Jan 21; 13(2). PMID: 33467027 Free PMC article.
Review.
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Efficacy of Margetuximab vs Trastuzumab in Patients With Pretreated ERBB2-Positive Advanced Breast Cancer: A Phase 3 Randomized Clinical Trial.
Hope S Rugo, Seock-Ah Im, +28 authors, Fatima Cardoso, Javier Cortés, Giuseppe Curigliano, Antonino Musolino, Mark D Pegram, Gail S Wright, Cristina Saura, Santiago Escrivá-de-Romaní, Michelino De Laurentiis, Christelle Levy, Ursa Brown-Glaberman, Jean-Marc Ferrero, Maaike de Boer, Sung-Bae Kim, Katarína Petráková, Denise A Yardley, Orit Freedman, Erik H Jakobsen, Bella Kaufman, Rinat Yerushalmi, Peter A Fasching, Jeffrey L Nordstrom, Ezio Bonvini, Scott Koenig, Sutton Edlich, Shengyan Hong, Edwin P Rock, William J Gradishar, SOPHIA Study Group. less
JAMA Oncol, 2021 Jan 23; 7(4). PMID: 33480963 Free PMC article.
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B Cell Aberrance in Lupus: the Ringleader and the Solution.
YuXue Nie, Lidan Zhao, Xuan Zhang.
Clin Rev Allergy Immunol, 2021 Feb 04; 62(2). PMID: 33534064
Review.
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An Acquired and Endogenous Glycocalyx Forms a Bidirectional "Don't Eat" and "Don't Eat Me" Barrier to Phagocytosis.
Paul R C Imbert, Amra Saric, +3 authors, Kayvon Pedram, Carolyn R Bertozzi, Sergio Grinstein, Spencer A Freeman. less
Curr Biol, 2020 Oct 24; 31(1). PMID: 33096038 Free PMC article.
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Understanding and Targeting Natural Killer Cell-Cancer-Associated Fibroblast Interactions in Pancreatic Ductal Adenocarcinoma.
Zoe X Malchiodi, Louis M Weiner.
Cancers (Basel), 2021 Jan 28; 13(3). PMID: 33499238 Free PMC article.
Review.
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Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination.
Matthew J Gorman, Nita Patel, +28 authors, Mimi Guebre-Xabier, Alex Zhu, Caroline Atyeo, Krista M Pullen, Carolin Loos, Yenny Goez-Gazi, Ricardo Carrion, Jing-Hui Tian, Dansu Yaun, Kathryn Bowman, Bin Zhou, Sonia Maciejewski, Marisa E McGrath, James Logue, Matthew B Frieman, David Montefiori, Colin Mann, Sharon Schendel, Fatima Amanat, Florian Krammer, Erica Ollmann Saphire, Douglas Lauffenburger, Ann M Greene, Alyse D Portnoff, Michael J Massare, Larry Ellingsworth, Gregory Glenn, Gale Smith, Galit Alter. less
bioRxiv, 2021 Feb 11;. PMID: 33564763 Free PMC article.
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Immunoglobulin G in Platelet-Derived Wound Healing Factors.
Elisa Seria, Sarah Samut Tagliaferro, +2 authors, Doreen Cutajar, Ruth Galdies, Alex Felice. less
Biomed Res Int, 2021 Feb 13; 2021. PMID: 33575328 Free PMC article.
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IVIG ameliorate inflammation in collagen-induced arthritis: projection for IVIG therapy in rheumatoid arthritis.
G Halpert, I Katz, +8 authors, O Shovman, S Tarasov, K K Ganina, N Petrova, M Tocut, A Volkov, I Barshack, M Blank, H Amital. less
Clin Exp Immunol, 2020 Oct 07; 203(3). PMID: 33020923 Free PMC article.
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Developing a 3D B Cell Lymphoma Culture System to Model Antibody Therapy.
Russell Foxall, Priyanka Narang, +6 authors, Bridget Glaysher, Elin Hub, Emma Teal, Mark C Coles, Margaret Ashton-Key, Stephen A Beers, Mark S Cragg. less
Front Immunol, 2021 Feb 26; 11. PMID: 33628205 Free PMC article.
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A Strategy to Elicit M2e-Specific Antibodies Using a Recombinant H7N9 Live Attenuated Influenza Vaccine Expressing Multiple M2e Tandem Repeats.
Daria Mezhenskaya, Irina Isakova-Sivak, +6 authors, Tatiana Kotomina, Victoria Matyushenko, Min-Chul Kim, Noopur Bhatnagar, Ki-Hye Kim, Sang-Moo Kang, Larisa Rudenko. less
Biomedicines, 2021 Feb 05; 9(2). PMID: 33535408 Free PMC article.
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Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination.
Galit Alter, Matthew Gorman, +28 authors, Nita Patel, Mimi Guebre-Xabier, Alex Zhu, Caroline Atyeo, Krista Pullen, Carolin Loos, Yenny Goez-Gazi, Ricardo Carrion, Jing-Hui Tian, Dansu Yuan, Kathryn Bowman, Bin Zhou, Sonia Maciejewski, Marisa McGrath, James Logue, Matthew Frieman, David Montefiori, Sharon Schendel, Erica Ollmann Saphire, Douglas Lauffenburger, Ann Greene, Alyse Portnoff, Michael Massare, Larry Ellingsworth, Gregory Glenn, Gale Smith, Colin Mann, Fatima Amanat, Florian Krammer. less
Res Sq, 2021 Feb 24;. PMID: 33619473 Free PMC article.
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The Rheumatology Drugs for COVID-19 Management: Which and When?
Fabiola Atzeni, Ignazio Francesco Masala, +8 authors, Javier Rodríguez-Carrio, Roberto Ríos-Garcés, Elisabetta Gerratana, Laura La Corte, Manuela Giallanza, Valeria Nucera, Agostino Riva, Gerard Espinosa, Ricard Cervera. less
J Clin Med, 2021 Mar 07; 10(4). PMID: 33669218 Free PMC article.
Review.
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FcγRIIB is a T cell checkpoint in antitumor immunity.
Clara R Farley, Anna B Morris, +5 authors, Marvi Tariq, Kelsey B Bennion, Sayalee Potdar, Ragini Kudchadkar, Michael C Lowe, Mandy L Ford. less
JCI Insight, 2021 Feb 23; 6(4). PMID: 33616086 Free PMC article.
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Engineered IgG1-Fc Molecules Define Valency Control of Cell Surface Fcγ Receptor Inhibition and Activation in Endosomes.
Elizabeth M Bailey, Amit Choudhury, +5 authors, Harika Vuppula, Daniel F Ortiz, John Schaeck, Anthony M Manning, Carlos J Bosques, Adam D Hoppe. less
Front Immunol, 2021 Mar 09; 11. PMID: 33679705 Free PMC article.
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Mesenchymal stem cell alongside exosomes as a novel cell-based therapy for COVID-19: A review study.
Meruyert Dauletova, Hafsan Hafsan, +3 authors, Negah Mahhengam, Angelina Olegovna Zekiy, Majid Ahmadi, Homayoon Siahmansouri. less
Clin Immunol, 2021 Mar 09; 226. PMID: 33684527 Free PMC article.
Review.
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A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans.
Astrid Hagelkruys, Gerald Wirnsberger, +16 authors, Johannes Stadlmann, Miriam Wöhner, Marion Horrer, Bojan Vilagos, Gustav Jonsson, Melanie Kogler, Luigi Tortola, Maria Novatchkova, Peter Bönelt, David Hoffmann, Rubina Koglgruber, Ulrike Steffen, Georg Schett, Meinrad Busslinger, Andreas Bergthaler, Christoph Klein, Josef M Penninger. less
J Exp Med, 2020 Sep 16; 218(1). PMID: 32930709 Free PMC article.
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Next generation of anti-PD-L1 Atezolizumab with enhanced anti-tumor efficacy in vivo.
Maohua Li, Rongqing Zhao, +9 authors, Jianxin Chen, Wenzhi Tian, Chenxi Xia, Xudong Liu, Yingzi Li, Song Li, Hunter Sun, Tong Shen, Wenlin Ren, Le Sun. less
Sci Rep, 2021 Mar 13; 11(1). PMID: 33707569 Free PMC article.
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Cellular and Humoral Immune Responses in Covid-19 and Immunotherapeutic Approaches.
Amal Hasan, Ebaa Al-Ozairi, +2 authors, Zahraa Al-Baqsumi, Rasheed Ahmad, Fahd Al-Mulla. less
Immunotargets Ther, 2021 Mar 18; 10. PMID: 33728277 Free PMC article.
Review.
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FcγRIIA expression accelerates nephritis and increases platelet activation in systemic lupus erythematosus.
Imene Melki, Isabelle Allaeys, +18 authors, Nicolas Tessandier, Benoit Mailhot, Nathalie Cloutier, Robert A Campbell, Jesse W Rowley, David Salem, Anne Zufferey, Audrée Laroche, Tania Lévesque, Natalie Patey, Joyce Rauch, Christian Lood, Arnaud Droit, Steven E McKenzie, Kellie R Machlus, Matthew T Rondina, Steve Lacroix, Paul R Fortin, Eric Boilard. less
Blood, 2020 Dec 18; 136(25). PMID: 33331924 Free PMC article.
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Identification of Reduced Host Transcriptomic Signatures for Tuberculosis Disease and Digital PCR-Based Validation and Quantification.
Harriet D Gliddon, Myrsini Kaforou, +18 authors, Mary Alikian, Dominic Habgood-Coote, Chenxi Zhou, Tolu Oni, Suzanne T Anderson, Andrew J Brent, Amelia C Crampin, Brian Eley, Robert Heyderman, Florian Kern, Paul R Langford, Tom H M Ottenhoff, Martin L Hibberd, Neil French, Victoria J Wright, Hazel M Dockrell, Lachlan J Coin, Robert J Wilkinson, Michael Levin. less
Front Immunol, 2021 Mar 26; 12. PMID: 33763081 Free PMC article.
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Potential Target Genes in the Development of Atrial Fibrillation: A Comprehensive Bioinformatics Analysis.
Liang Liu, Yun Yu, +7 authors, Long-Long Hu, Quan-Bin Dong, Feng Hu, Ling-Juan Zhu, Qian Liang, Ling-Ling Yu, Hui-Hui Bao, Xiao-Shu Cheng. less
Med Sci Monit, 2021 Mar 21; 27. PMID: 33741890 Free PMC article.
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Human antiviral B cell responses: Emerging lessons from hepatitis B and COVID-19.
Alice R Burton, Mala K Maini.
Immunol Rev, 2021 Feb 10; 299(1). PMID: 33559128 Free PMC article.
Review.
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Harnessing and Enhancing Macrophage Phagocytosis for Cancer Therapy.
Siqi Chen, Seigmund W T Lai, Christine E Brown, Mingye Feng.
Front Immunol, 2021 Apr 02; 12. PMID: 33790906 Free PMC article.
Review.
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Germinal center reactions in tertiary lymphoid structures associate with neoantigen burden, humoral immunity and long-term survivorship in pancreatic cancer.
Andrew J Gunderson, Venkatesh Rajamanickam, +17 authors, Cynthia Bui, Brady Bernard, Joanna Pucilowska, Carmen Ballesteros-Merino, Mark Schmidt, Kayla McCarty, Michaela Philips, Brian Piening, Christopher Dubay, Terry Medler, Phillipa Newell, Paul Hansen, Eric Tran, Ephraim Tang, Carlo Bifulco, Marka Crittenden, Michael Gough, Kristina H Young. less
Oncoimmunology, 2021 Apr 03; 10(1). PMID: 33796412 Free PMC article.
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Bruton's tyrosine kinase: an emerging targeted therapy in myeloid cells within the tumor microenvironment.
Logan Good, Brooke Benner, William E Carson.
Cancer Immunol Immunother, 2021 Apr 06; 70(9). PMID: 33818636 Free PMC article.
Review.
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Immunological memory in rheumatic inflammation - a roadblock to tolerance induction.
Patrick Maschmeyer, Hyun-Dong Chang, +4 authors, Qingyu Cheng, Mir-Farzin Mashreghi, Falk Hiepe, Tobias Alexander, Andreas Radbruch. less
Nat Rev Rheumatol, 2021 Apr 08; 17(5). PMID: 33824526
Review.
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The Advances and Challenges of NK Cell-Based Cancer Immunotherapy.
Synat Kang, Xuefeng Gao, +3 authors, Li Zhang, Erna Yang, Yonghui Li, Li Yu. less
Curr Oncol, 2021 Mar 04; 28(2). PMID: 33652996 Free PMC article.
Review.
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Spontaneous Breathing and Evolving Phenotypes of Lung Damage in Patients with COVID-19: Review of Current Evidence and Forecast of a New Scenario.
Roberto Tonelli, Alessandro Marchioni, +12 authors, Luca Tabbì, Riccardo Fantini, Stefano Busani, Ivana Castaniere, Dario Andrisani, Filippo Gozzi, Giulia Bruzzi, Linda Manicardi, Jacopo Demurtas, Alessandro Andreani, Gaia Francesca Cappiello, Anna Valeria Samarelli, Enrico Clini. less
J Clin Med, 2021 Apr 04; 10(5). PMID: 33801368 Free PMC article.
Review.
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Fcγ receptors on aging neutrophils.
Thaís Helena Gasparoto, Thalita Marcato Dalboni, +6 authors, Nádia Ghinelli Amôr, Aneli Eiko Abe, Graziela Perri, Vanessa Soares Lara, Narciso Almeida Vieira, Carlos Teodoro Gasparoto, Ana Paula Campanelli. less
J Appl Oral Sci, 2021 Apr 08; 29. PMID: 33825754 Free PMC article.
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C-Reactive Protein Suppresses the Th17 Response Indirectly by Attenuating the Antigen Presentation Ability of Monocyte Derived Dendritic Cells in Experimental Autoimmune Encephalomyelitis.
Zhi-Yuan Shen, Yi Zheng, +5 authors, Maggie K Pecsok, Ke Wang, Wei Li, Min-Jie Gong, Feng Wu, Lin Zhang. less
Front Immunol, 2021 Apr 13; 12. PMID: 33841391 Free PMC article.
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NK Cell Adoptive Immunotherapy of Cancer: Evaluating Recognition Strategies and Overcoming Limitations.
Carlos E Sanchez, Ehsan P Dowlati, +4 authors, Ashley E Geiger, Kajal Chaudhry, Matthew A Tovar, Catherine M Bollard, Conrad Russell Y Cruz. less
Transplant Cell Ther, 2020 Oct 03; 27(1). PMID: 33007496 |
