Review
. 2007 Dec; 8(1):34-47.
doi: 10.1038/nri2206.

Fcgamma receptors as regulators of immune responses

Falk Nimmerjahn 1 Jeffrey V Ravetch  
Affiliations
  • PMID: 18064051
  •     1149 citations

Abstract

In addition to their role in binding antigen, antibodies can regulate immune responses through interacting with Fc receptors (FcRs). In recent years, significant progress has been made in understanding the mechanisms that regulate the activity of IgG antibodies in vivo. In this Review, we discuss recent studies addressing the multifaceted roles of FcRs for IgG (FcgammaRs) in the immune system and how this knowledge could be translated into novel therapeutic strategies to treat human autoimmune, infectious or malignant diseases.

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Defining the immunological phenotype of Fc receptor-like B (FCRLB) deficient mice: Confounding role of the inhibitory FcγRIIb.
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Deficiency of activating Fcγ-receptors reduces hepatic clearance and deposition of IC and increases CIC levels in mercury-induced autoimmunity.
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High affinity allele for the gene of FCGR3A is risk factor for HIV infection and progression.
Bhawna Poonia, Gustavo H Kijak, C David Pauza.
PLoS One, 2010 Dec 29; 5(12). PMID: 21187939    Free PMC article.
Antibody-mediated neutralization of flaviviruses: a reductionist view.
Kimberly A Dowd, Theodore C Pierson.
Virology, 2011 Jan 25; 411(2). PMID: 21255816    Free PMC article.
Highly Cited. Review.
Advances in the assessment and control of the effector functions of therapeutic antibodies.
Xu-Rong Jiang, An Song, +7 authors, Mark Schenerman.
Nat Rev Drug Discov, 2011 Feb 02; 10(2). PMID: 21283105
Highly Cited. Review.
Chemokine receptor CXCR2 mediates bacterial clearance rather than neutrophil recruitment in a murine model of pneumonic plague.
Nicholas A Eisele, Hanni Lee-Lewis, +2 authors, Deborah M Anderson.
Am J Pathol, 2011 Mar 02; 178(3). PMID: 21356370    Free PMC article.
Target-specific mechanics of phagocytosis: protrusive neutrophil response to zymosan differs from the uptake of antibody-tagged pathogens.
Cheng-Yuk Lee, Marc Herant, Volkmar Heinrich.
J Cell Sci, 2011 Mar 10; 124(Pt 7). PMID: 21385838    Free PMC article.
Characterization of monoclonal antibodies to terminal and internal O-antigen epitopes of Francisella tularensis lipopolysaccharide.
Marly I Roche, Zhaohua Lu, Julia H Hui, Jacqueline Sharon.
Hybridoma (Larchmt), 2011 Apr 07; 30(1). PMID: 21466282    Free PMC article.
Glycoengineered Pichia produced anti-HER2 is comparable to trastuzumab in preclinical study.
Ningyan Zhang, Liming Liu, +16 authors, Dongxing Zha.
MAbs, 2011 Apr 14; 3(3). PMID: 21487242    Free PMC article.
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies.
Daniel A Winer, Shawn Winer, +16 authors, Edgar G Engleman.
Nat Med, 2011 Apr 19; 17(5). PMID: 21499269    Free PMC article.
Highly Cited.
Neuronal Fc-gamma receptor I mediated excitatory effects of IgG immune complex on rat dorsal root ganglion neurons.
Lintao Qu, Pu Zhang, Robert H LaMotte, Chao Ma.
Brain Behav Immun, 2011 Apr 28; 25(7). PMID: 21521651    Free PMC article.
Bi-specific aptamers mediating tumor cell lysis.
Achim Boltz, Birgit Piater, +3 authors, Bjoern Hock.
J Biol Chem, 2011 May 03; 286(24). PMID: 21531729    Free PMC article.
Aim2 deficiency in mice suppresses the expression of the inhibitory Fcgamma receptor (FcgammaRIIB) through the induction of the IFN-inducible p202, a lupus susceptibility protein.
Ravichandran Panchanathan, Hui Shen, +4 authors, Divaker Choubey.
J Immunol, 2011 May 10; 186(12). PMID: 21551362    Free PMC article.
Decreased Fc receptor expression on innate immune cells is associated with impaired antibody-mediated cellular phagocytic activity in chronically HIV-1 infected individuals.
Anne-Sophie Dugast, Andrew Tonelli, +8 authors, Galit Alter.
Virology, 2011 May 14; 415(2). PMID: 21565376    Free PMC article.
Recombinant HPV16 E7 assembled into particles induces an immune response and specific tumour protection administered without adjuvant in an animal model.
Linda Petrone, Maria G Ammendolia, +4 authors, Paola Di Bonito.
J Transl Med, 2011 May 20; 9. PMID: 21592382    Free PMC article.
PLD1 rather than PLD2 regulates phorbol-ester-, adhesion-dependent and Fc{gamma}-receptor-stimulated ROS production in neutrophils.
Laura J Norton, Qifeng Zhang, +7 authors, Michael J O Wakelam.
J Cell Sci, 2011 May 26; 124(Pt 12). PMID: 21610093    Free PMC article.
High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations.
Maja Pucić, Ana Knezević, +16 authors, Gordan Lauc.
Mol Cell Proteomics, 2011 Jun 10; 10(10). PMID: 21653738    Free PMC article.
Highly Cited.
Passively administered pooled human immunoglobulins exert IL-10 dependent anti-inflammatory effects that protect against fatal HSV encephalitis.
Chandran Ramakrishna, Alain N S Newo, Yueh-Wei Shen, Edouard Cantin.
PLoS Pathog, 2011 Jun 10; 7(6). PMID: 21655109    Free PMC article.
Clinical cancer therapy by NK cells via antibody-dependent cell-mediated cytotoxicity.
Kory L Alderson, Paul M Sondel.
J Biomed Biotechnol, 2011 Jun 11; 2011. PMID: 21660134    Free PMC article.
Review.
LyGDI, a novel SHIP-interacting protein, is a negative regulator of FcγR-mediated phagocytosis.
Payal Mehta, Anne-Sophie Wavreille, +8 authors, Susheela Tridandapani.
PLoS One, 2011 Jun 23; 6(6). PMID: 21695085    Free PMC article.
The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells.
Betty Y Chang, Min Mei Huang, +5 authors, Joseph J Buggy.
Arthritis Res Ther, 2011 Jul 15; 13(4). PMID: 21752263    Free PMC article.
Unique carbohydrate-carbohydrate interactions are required for high affinity binding between FcgammaRIII and antibodies lacking core fucose.
Claudia Ferrara, Sandra Grau, +9 authors, Jörg Benz.
Proc Natl Acad Sci U S A, 2011 Jul 20; 108(31). PMID: 21768335    Free PMC article.
Highly Cited.
Anti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cells.
Diego G Silva, Stephen R Daley, +6 authors, Carola G Vinuesa.
Diabetes, 2011 Jul 27; 60(8). PMID: 21788582    Free PMC article.
β2-microglobulin is required for the full expression of xenobiotic-induced systemic autoimmunity.
Kenneth M Pollard, Per Hultman, +3 authors, Dwight H Konoc.
J Immunotoxicol, 2011 Jul 29; 8(3). PMID: 21793797    Free PMC article.
HER2-based recombinant immunogen to target DCs through FcγRs for cancer immunotherapy.
Ilaria Grazia Zizzari, Filippo Veglia, +12 authors, Aurelia Rughetti.
J Mol Med (Berl), 2011 Aug 17; 89(12). PMID: 21845448    Free PMC article.
A panel of IgG1 b12 variants with selectively diminished or enhanced affinity for Fcγ receptors to define the role of effector functions in protection against HIV.
Brian Moldt, Niccole Schultz, +6 authors, Dennis R Burton.
J Virol, 2011 Aug 19; 85(20). PMID: 21849450    Free PMC article.
Inhibitory Fcγ receptor engagement drives adjuvant and anti-tumor activities of agonistic CD40 antibodies.
Fubin Li, Jeffrey V Ravetch.
Science, 2011 Aug 20; 333(6045). PMID: 21852502    Free PMC article.
Highly Cited.
An essential role for Stat3 in regulating IgG immune complex-induced pulmonary inflammation.
Huifang Tang, Chunguang Yan, +4 authors, Hongwei Gao.
FASEB J, 2011 Aug 24; 25(12). PMID: 21859893    Free PMC article.
The in vivo mechanism of action of CD20 monoclonal antibodies depends on local tumor burden.
Peter Boross, J H Marco Jansen, +8 authors, Jeanette H W Leusen.
Haematologica, 2011 Sep 02; 96(12). PMID: 21880632    Free PMC article.
T cell activation by terminal complex of complement and immune complexes.
Anil K Chauhan, Terry L Moore.
J Biol Chem, 2011 Sep 09; 286(44). PMID: 21900254    Free PMC article.
Emerging roles for the interferon-inducible p200-family proteins in sex bias in systemic lupus erythematosus.
Divaker Choubey, Ravichandran Panchanathan, +2 authors, Hongzhu Liu.
J Interferon Cytokine Res, 2011 Sep 10; 31(12). PMID: 21902548    Free PMC article.
Review.
TOSO, the Fcmicro receptor, is highly expressed on chronic lymphocytic leukemia B cells, internalizes upon IgM binding, shuttles to the lysosome, and is downregulated in response to TLR activation.
Bérengère Vire, Alexandre David, Adrian Wiestner.
J Immunol, 2011 Sep 13; 187(8). PMID: 21908732    Free PMC article.
Blurred line between chemotactic chase and phagocytic consumption: an immunophysical single-cell perspective.
Volkmar Heinrich, Cheng-Yuk Lee.
J Cell Sci, 2011 Sep 15; 124(Pt 18). PMID: 21914817    Free PMC article.
Review.
Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells.
Andrew J Gross, Irina Proekt, Anthony L DeFranco.
Eur J Immunol, 2011 Sep 20; 41(12). PMID: 21928281    Free PMC article.
Coupling of Fcγ receptor I to Fcγ receptor IIb by SRC kinase mediates C-reactive protein impairment of endothelial function.
Nathan C Sundgren, Weifei Zhu, +6 authors, Philip W Shaul.
Circ Res, 2011 Sep 24; 109(10). PMID: 21940940    Free PMC article.
TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells.
Hiroaki Ito, Jessica A Hamerman.
Eur J Immunol, 2011 Oct 01; 42(1). PMID: 21956652    Free PMC article.
Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC-STAMP).
Ya-Hui Chiu, Kofi A Mensah, +8 authors, Christopher T Ritchlin.
J Bone Miner Res, 2011 Oct 12; 27(1). PMID: 21987375    Free PMC article.
Antibody-Mediated Fcγ Receptor-Based Mechanisms of HIV Inhibition: Recent Findings and New Vaccination Strategies.
Vincent Holl, Maryse Peressin, Christiane Moog.
Viruses, 2009 Dec 01; 1(3). PMID: 21994593    Free PMC article.
Chemoenzymatic synthesis and Fcγ receptor binding of homogeneous glycoforms of antibody Fc domain. Presence of a bisecting sugar moiety enhances the affinity of Fc to FcγIIIa receptor.
Guozhang Zou, Hirofumi Ochiai, +3 authors, Lai-Xi Wang.
J Am Chem Soc, 2011 Oct 19; 133(46). PMID: 22004528    Free PMC article.
Multiple mechanisms of immune suppression by B lymphocytes.
Matthew W Klinker, Steven K Lundy.
Mol Med, 2011 Oct 29; 18. PMID: 22033729    Free PMC article.
Review.
Activation of cord blood myeloid dendritic cells by Trypanosoma cruzi and parasite-specific antibodies, proliferation of CD8+ T cells, and production of IFN-γ.
Patricia Rodriguez, Yves Carlier, Carine Truyens.
Med Microbiol Immunol, 2011 Nov 01; 201(2). PMID: 22037700
Chronic alloantibody mediated rejection.
R Neal Smith, Robert B Colvin.
Semin Immunol, 2011 Nov 05; 24(2). PMID: 22051115    Free PMC article.
Review.
Differential inhibition of trastuzumab- and cetuximab-induced cytotoxicity of cancer cells by immunoglobulin G1 expressing different GM allotypes.
A M Namboodiri, J P Pandey.
Clin Exp Immunol, 2011 Nov 09; 166(3). PMID: 22059994    Free PMC article.
Fcγ receptor IIB (FcγRIIB) maintains humoral tolerance in the human immune system in vivo.
Anne Baerenwaldt, Anja Lux, +5 authors, Falk Nimmerjahn.
Proc Natl Acad Sci U S A, 2011 Nov 09; 108(46). PMID: 22065769    Free PMC article.
CD83-stimulated monocytes suppress T-cell immune responses through production of prostaglandin E2.
Liwen Chen, Yibei Zhu, +3 authors, Xueguang Zhang.
Proc Natl Acad Sci U S A, 2011 Nov 09; 108(46). PMID: 22065790    Free PMC article.
Cell-associated flagella enhance the protection conferred by mucosally-administered attenuated Salmonella Paratyphi A vaccines.
Orit Gat, James E Galen, +5 authors, Myron M Levine.
PLoS Negl Trop Dis, 2011 Nov 10; 5(11). PMID: 22069504    Free PMC article.
Distinct regulation of murine lupus susceptibility genes by the IRF5/Blimp-1 axis.
Ravichandran Panchanathan, Hongzhu Liu, +4 authors, Divaker Choubey.
J Immunol, 2011 Nov 26; 188(1). PMID: 22116829    Free PMC article.
The in vitro resistance of IgG2 to proteolytic attack concurs with a comparative paucity of autoantibodies against peptide analogs of the IgG2 hinge.
Randall J Brezski, Allison Oberholtzer, Brandy Strake, Robert E Jordan.
MAbs, 2011 Nov 30; 3(6). PMID: 22123056    Free PMC article.
The impact of glycosylation on monoclonal antibody conformation and stability.
Kai Zheng, Christopher Bantog, Robert Bayer.
MAbs, 2011 Nov 30; 3(6). PMID: 22123061    Free PMC article.
Anti-tumor activity and toxicokinetics analysis of MGAH22, an anti-HER2 monoclonal antibody with enhanced Fcγ receptor binding properties.
Jeffrey L Nordstrom, Sergey Gorlatov, +12 authors, Ezio Bonvini.
Breast Cancer Res, 2011 Dec 02; 13(6). PMID: 22129105    Free PMC article.
Emerging technologies for making glycan-defined glycoproteins.
Lai-Xi Wang, Joseph V Lomino.
ACS Chem Biol, 2011 Dec 07; 7(1). PMID: 22141574    Free PMC article.
Review.
C5a-regulated CCAAT/enhancer-binding proteins β and δ are essential in Fcγ receptor-mediated inflammatory cytokine and chemokine production in macrophages.
Chunguang Yan, Mei Zhu, +2 authors, Hongwei Gao.
J Biol Chem, 2011 Dec 08; 287(5). PMID: 22147692    Free PMC article.
Age related changes in microglial phenotype vary between CNS regions: grey versus white matter differences.
Adam D Hart, Andreas Wyttenbach, V Hugh Perry, Jessica L Teeling.
Brain Behav Immun, 2011 Dec 14; 26(5). PMID: 22155499    Free PMC article.
Immune mediated diseases and immune modulation in the neurocritical care unit.
Gloria von Geldern, Thomas McPharlin, Kyra Becker.
Neurotherapeutics, 2011 Dec 14; 9(1). PMID: 22161307    Free PMC article.
Review.
Role of novel rat-specific Fc receptor in macrophage activation associated with crescentic glomerulonephritis.
Theresa H Page, Zelpha D'Souza, +5 authors, Jacques Behmoaras.
J Biol Chem, 2011 Dec 21; 287(8). PMID: 22184119    Free PMC article.
FcγRIIIa expression on monocytes in rheumatoid arthritis: role in immune-complex stimulated TNF production and non-response to methotrexate therapy.
Dawn L Cooper, Stephen G Martin, +7 authors, Ann W Morgan.
PLoS One, 2012 Jan 12; 7(1). PMID: 22235253    Free PMC article.
Immune complexes and late complement proteins trigger activation of Syk tyrosine kinase in human CD4(+) T cells.
A K Chauhan, T L Moore.
Clin Exp Immunol, 2012 Jan 13; 167(2). PMID: 22235999    Free PMC article.
Antibody inhibition of a viral type 1 interferon decoy receptor cures a viral disease by restoring interferon signaling in the liver.
Ren-Huan Xu, Daniel Rubio, +7 authors, Luis J Sigal.
PLoS Pathog, 2012 Jan 14; 8(1). PMID: 22241999    Free PMC article.
A serotype 3 pneumococcal capsular polysaccharide-specific monoclonal antibody requires Fcγ receptor III and macrophages to mediate protection against pneumococcal pneumonia in mice.
Sarah Weber, Haijun Tian, Nico van Rooijen, Liise-Anne Pirofski.
Infect Immun, 2012 Feb 01; 80(4). PMID: 22290146    Free PMC article.
The influence of ACPA status and characteristics on the course of RA.
Annemiek Willemze, Leendert A Trouw, René E M Toes, Tom W J Huizinga.
Nat Rev Rheumatol, 2012 Feb 02; 8(3). PMID: 22293763
Review.
Feasibility of cross-protective vaccination against flaviviruses of the Japanese encephalitis serocomplex.
Mario Lobigs, Michael S Diamond.
Expert Rev Vaccines, 2012 Feb 09; 11(2). PMID: 22309667    Free PMC article.
Review.
Analytical characterization of ch14.18: a mouse-human chimeric disialoganglioside-specific therapeutic antibody.
Gopalan Soman, Abraham T Kallarakal, +6 authors, George Mitra.
MAbs, 2012 Feb 14; 4(1). PMID: 22327432    Free PMC article.
Polymeric human Fc-fusion proteins with modified effector functions.
David N A Mekhaiel, Daniel M Czajkowsky, +9 authors, Richard J Pleass.
Sci Rep, 2012 Feb 23; 1. PMID: 22355641    Free PMC article.
ITAM-coupled receptors inhibit IFNAR signaling and alter macrophage responses to TLR4 and Listeria monocytogenes.
Linda Huynh, Lu Wang, +2 authors, Lionel B Ivashkiv.
J Immunol, 2012 Mar 01; 188(7). PMID: 22368279    Free PMC article.
Intravenous immunoglobulins modulate neutrophil activation and vascular injury through FcγRIII and SHP-1.
Jung-Eun Jang, Andrés Hidalgo, Paul S Frenette.
Circ Res, 2012 Mar 15; 110(8). PMID: 22415018    Free PMC article.
The role of sialic acid as a modulator of the anti-inflammatory activity of IgG.
Sybille Böhm, Inessa Schwab, Anja Lux, Falk Nimmerjahn.
Semin Immunopathol, 2012 Mar 23; 34(3). PMID: 22437760
Review.
Lyn but not Fyn kinase controls IgG-mediated systemic anaphylaxis.
Yves T Falanga, Natalia S Chaimowitz, +14 authors, John J Ryan.
J Immunol, 2012 Mar 28; 188(9). PMID: 22450804    Free PMC article.
Fc receptor-targeted therapies for the treatment of inflammation, cancer and beyond.
P Mark Hogarth, Geoffrey A Pietersz.
Nat Rev Drug Discov, 2012 Mar 31; 11(4). PMID: 22460124
Highly Cited. Review.
Prevalence of collagen VII-specific autoantibodies in patients with autoimmune and inflammatory diseases.
Emilia Licarete, Susanne Ganz, +9 authors, Cassian Sitaru.
BMC Immunol, 2012 Apr 05; 13. PMID: 22471736    Free PMC article.
Mouse model recapitulating human Fcγ receptor structural and functional diversity.
Patrick Smith, David J DiLillo, +2 authors, Jeffrey V Ravetch.
Proc Natl Acad Sci U S A, 2012 Apr 05; 109(16). PMID: 22474370    Free PMC article.
Highly Cited.
The biological significance of evolution in autoimmune phenomena.
Carlos A Cañas, Felipe Cañas.
Autoimmune Dis, 2012 Apr 07; 2012. PMID: 22482039    Free PMC article.
Selective deactivation of serum IgG: a general strategy for the enhancement of monoclonal antibody receptor interactions.
Kavitha Baruah, Thomas A Bowden, +3 authors, Christopher N Scanlan.
J Mol Biol, 2012 Apr 10; 420(1-2). PMID: 22484364    Free PMC article.
Cutting edge: human FcRL4 and FcRL5 are receptors for IgA and IgG.
Timothy J Wilson, Anja Fuchs, Marco Colonna.
J Immunol, 2012 Apr 12; 188(10). PMID: 22491254    Free PMC article.
FcγRI mediates serum amyloid P inhibition of fibrocyte differentiation.
Jeffrey R Crawford, Darrell Pilling, Richard H Gomer.
J Leukoc Biol, 2012 Apr 12; 92(4). PMID: 22493081    Free PMC article.
Cancer and innate immune system interactions: translational potentials for cancer immunotherapy.
Yanan Liu, Gang Zeng.
J Immunother, 2012 Apr 13; 35(4). PMID: 22495387    Free PMC article.
Review.
Lepidopteran cells, an alternative for the production of recombinant antibodies?
Martine Cérutti, Josée Golay.
MAbs, 2012 Apr 26; 4(3). PMID: 22531440    Free PMC article.
Review.
Quantitative evaluation of fucose reducing effects in a humanized antibody on Fcγ receptor binding and antibody-dependent cell-mediated cytotoxicity activities.
Shan Chung, Valerie Quarmby, +9 authors, An Song.
MAbs, 2012 Apr 26; 4(3). PMID: 22531441    Free PMC article.
Development and validation of an antibody-dependent cell-mediated cytotoxicity-reporter gene assay.
Bhavin S Parekh, Elaine Berger, +6 authors, Dennis Gately.
MAbs, 2012 Apr 26; 4(3). PMID: 22531445    Free PMC article.
Immunopotentiating properties of a multispecific α-anti-idiotype antibody.
Tays Hernández, Cristina Mateo de Acosta, Rolando Pérez.
MAbs, 2012 Apr 26; 4(3). PMID: 22531446    Free PMC article.
Exacerbation of collagen induced arthritis by Fcγ receptor targeted collagen peptide due to enhanced inflammatory chemokine and cytokine production.
Eszter Szarka, Zsuzsa Neer, +6 authors, Gabriella Sármay.
Biologics, 2012 Apr 26; 6. PMID: 22532778    Free PMC article.
Antibodies targeting dengue virus envelope domain III are not required for serotype-specific protection or prevention of enhancement in vivo.
Katherine L Williams, Wahala M P B Wahala, +2 authors, Eva Harris.
Virology, 2012 Apr 28; 429(1). PMID: 22537810    Free PMC article.
Prevention and treatment of allergic inflammation by an Fcγ-Der f2 fusion protein in a murine model of dust mite-induced asthma.
Li-hui Lin, Ping Zheng, +6 authors, Li Li.
Immunol Res, 2012 Apr 28; 52(3). PMID: 22539132
Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life.
Jan Terje Andersen, Stian Foss, +5 authors, Inger Sandlie.
J Biol Chem, 2012 May 10; 287(27). PMID: 22570488    Free PMC article.
Ultrasensitive capillary electrophoretic analysis of potentially immunogenic carbohydrate residues in biologics: galactose-α-1,3-galactose containing oligosaccharides.
Zoltan Szabo, Andras Guttman, +3 authors, Barry L Karger.
Mol Pharm, 2012 May 11; 9(6). PMID: 22571495    Free PMC article.
NMR characterization of immunoglobulin G Fc glycan motion on enzymatic sialylation.
Adam W Barb, Lu Meng, +3 authors, James H Prestegard.
Biochemistry, 2012 May 12; 51(22). PMID: 22574931    Free PMC article.
The Fyn-STAT5 Pathway: A New Frontier in IgE- and IgG-Mediated Mast Cell Signaling.
Nicholas A Pullen, Yves T Falanga, Johanna K Morales, John J Ryan.
Front Immunol, 2012 May 18; 3. PMID: 22593761    Free PMC article.
Evolutionary history of copy-number-variable locus for the low-affinity Fcγ receptor: mutation rate, autoimmune disease, and the legacy of helminth infection.
Lee R Machado, Robert J Hardwick, +4 authors, Edward J Hollox.
Am J Hum Genet, 2012 May 23; 90(6). PMID: 22608500    Free PMC article.
Antiphagocytic function of an IgG glycosyl hydrolase from Streptococcus equi subsp. equi and its use as a vaccine component.
Margareta Flock, Lars Frykberg, +2 authors, Jan-Ingmar Flock.
Infect Immun, 2012 May 23; 80(8). PMID: 22615244    Free PMC article.
Increasing the clinical efficacy of NK and antibody-mediated cancer immunotherapy: potential predictors of successful clinical outcome based on observations in high-risk neuroblastoma.
Tony A Koehn, Lori L Trimble, +5 authors, Paul M Sondel.
Front Pharmacol, 2012 May 25; 3. PMID: 22623917    Free PMC article.
High-content live-cell imaging assay used to establish mechanism of trastuzumab emtansine (T-DM1)--mediated inhibition of platelet production.
Jonathan N Thon, Matthew T Devine, +2 authors, Joseph E Italiano.
Blood, 2012 Jun 06; 120(10). PMID: 22665936    Free PMC article.
Glycans in sera of amyotrophic lateral sclerosis patients and their role in killing neuronal cells.
Meital Edri-Brami, Benyamin Rosental, +7 authors, Rachel G Lichtenstein.
PLoS One, 2012 Jun 06; 7(5). PMID: 22666317    Free PMC article.
Antibody-dependent cellular cytotoxicity against primary HIV-infected CD4+ T cells is directly associated with the magnitude of surface IgG binding.
Adjoa Smalls-Mantey, Nicole Doria-Rose, +13 authors, Mark Connors.
J Virol, 2012 Jun 08; 86(16). PMID: 22674985    Free PMC article.
Production, characterization, and pharmacokinetic properties of antibodies with N-linked mannose-5 glycans.
Marcella Yu, Darren Brown, +6 authors, Robert Bayer.
MAbs, 2012 Jun 16; 4(4). PMID: 22699308    Free PMC article.
Fc-Gamma Receptor 3B Copy Number Variation Is Not a Risk Factor for Behçet's Disease.
Rachel Black, Sue Lester, +8 authors, Fereydoun Davatchi.
Int J Rheumatol, 2012 Jun 16; 2012. PMID: 22701122    Free PMC article.
Apoptotic and antitumor activity of death receptor antibodies require inhibitory Fcγ receptor engagement.
Fubin Li, Jeffrey V Ravetch.
Proc Natl Acad Sci U S A, 2012 Jun 23; 109(27). PMID: 22723355    Free PMC article.
The interactions of human neutrophils with shiga toxins and related plant toxins: danger or safety?
Maurizio Brigotti.
Toxins (Basel), 2012 Jun 29; 4(3). PMID: 22741061    Free PMC article.
Review.
Chemoenzymatic glycoengineering of intact IgG antibodies for gain of functions.
Wei Huang, John Giddens, +2 authors, Lai-Xi Wang.
J Am Chem Soc, 2012 Jul 04; 134(29). PMID: 22747414    Free PMC article.
Highly Cited.
Revisiting the role of glycosylation in the structure of human IgG Fc.
M Jack Borrok, Sang Taek Jung, +2 authors, George Georgiou.
ACS Chem Biol, 2012 Jul 04; 7(9). PMID: 22747430    Free PMC article.
Antibody-recruiting molecules: an emerging paradigm for engaging immune function in treating human disease.
Patrick J McEnaney, Christopher G Parker, Andrew X Zhang, David A Spiegel.
ACS Chem Biol, 2012 Jul 05; 7(7). PMID: 22758917    Free PMC article.
Systematic Review.
Association of FCRL4 polymorphisms on disease susceptibility and severity of ankylosing spondylitis in Chinese Han population.
Zhen Zeng, Zhenhua Duan, +11 authors, Faming Pan.
Clin Rheumatol, 2012 Jul 11; 31(10). PMID: 22777505
Transient receptor potential canonical 3 (TRPC3) is required for IgG immune complex-induced excitation of the rat dorsal root ganglion neurons.
Lintao Qu, Yumei Li, +3 authors, Chao Ma.
J Neurosci, 2012 Jul 13; 32(28). PMID: 22787041    Free PMC article.
Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study.
David H Cribbs, Nicole C Berchtold, +4 authors, Carl W Cotman.
J Neuroinflammation, 2012 Jul 25; 9. PMID: 22824372    Free PMC article.
Highly Cited.
Fc-fusion proteins: new developments and future perspectives.
Daniel M Czajkowsky, Jun Hu, Zhifeng Shao, Richard J Pleass.
EMBO Mol Med, 2012 Jul 28; 4(10). PMID: 22837174    Free PMC article.
Highly Cited. Review.
Interferon-inducible Ifi200-family genes as modifiers of lupus susceptibility.
Divaker Choubey.
Immunol Lett, 2012 Jul 31; 147(1-2). PMID: 22841963    Free PMC article.
Review.
Cross-presentation of IgG-containing immune complexes.
Kristi Baker, Timo Rath, +2 authors, Richard S Blumberg.
Cell Mol Life Sci, 2012 Aug 01; 70(8). PMID: 22847331    Free PMC article.
Review.
Association of Fcγ receptor IIB polymorphism with cryptococcal meningitis in HIV-uninfected Chinese patients.
Xiu-Ping Hu, Ji-Qin Wu, +5 authors, Xin-Hua Weng.
PLoS One, 2012 Aug 11; 7(8). PMID: 22879986    Free PMC article.
Genetic polymorphisms of FCGR2A encoding Fcγ receptor IIa in a Japanese population and functional analysis of the L273P variant.
Minoru Tada, Akiko Ishii-Watabe, +23 authors, Yasuhiro Matsumura.
Immunogenetics, 2012 Aug 21; 64(12). PMID: 22903236
A general requirement for FcγRIIB co-engagement of agonistic anti-TNFR antibodies.
Fubin Li, Jeffrey V Ravetch.
Cell Cycle, 2012 Aug 25; 11(18). PMID: 22918247    Free PMC article.
Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1.
Christian M Karsten, Manoj K Pandey, +23 authors, Jörg Köhl.
Nat Med, 2012 Aug 28; 18(9). PMID: 22922409    Free PMC article.
Highly Cited.
ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge.
Michael D Alpert, Jackson D Harvey, +9 authors, David T Evans.
PLoS Pathog, 2012 Aug 29; 8(8). PMID: 22927823    Free PMC article.
Highly Cited.
A novel assay for antibody-dependent cell-mediated cytotoxicity against HIV-1- or SIV-infected cells reveals incomplete overlap with antibodies measured by neutralization and binding assays.
Michael D Alpert, Lisa N Heyer, +4 authors, David T Evans.
J Virol, 2012 Aug 31; 86(22). PMID: 22933282    Free PMC article.
Molecular characterization of novel trispecific ErbB-cMet-IGF1R antibodies and their antigen-binding properties.
R Castoldi, U Jucknischke, +5 authors, C Sustmann.
Protein Eng Des Sel, 2012 Sep 01; 25(10). PMID: 22936109    Free PMC article.
Fc gamma receptor CD64 modulates the inhibitory activity of infliximab.
Kacper A Wojtal, Gerhard Rogler, +7 authors, Stephan R Vavricka.
PLoS One, 2012 Sep 01; 7(8). PMID: 22937039    Free PMC article.
A sweet spot to control complement-induced inflammation.
Daniel Ricklin, Edimara S Reis, John D Lambris.
Nat Med, 2012 Sep 11; 18(9). PMID: 22961162
T cell responses induced by adenoviral vectored vaccines can be adjuvanted by fusion of antigen to the oligomerization domain of C4b-binding protein.
Emily K Forbes, Simone C de Cassan, +8 authors, Simon J Draper.
PLoS One, 2012 Sep 18; 7(9). PMID: 22984589    Free PMC article.
Critical role of the IgM Fc receptor in IgM homeostasis, B-cell survival, and humoral immune responses.
Rika Ouchida, Hiromi Mori, +5 authors, Ji-Yang Wang.
Proc Natl Acad Sci U S A, 2012 Sep 19; 109(40). PMID: 22988094    Free PMC article.
The Plasmodium falciparum erythrocyte invasion ligand Pfrh4 as a target of functional and protective human antibodies against malaria.
Linda Reiling, Jack S Richards, +14 authors, James G Beeson.
PLoS One, 2012 Oct 03; 7(9). PMID: 23028883    Free PMC article.
FCGR2C genotyping by pyrosequencing reveals linkage disequilibrium with FCGR3A V158F and FCGR2A H131R polymorphisms in a Caucasian population.
Julien Lejeune, Benoît Piègu, +3 authors, Gilles Thibault.
MAbs, 2012 Oct 04; 4(6). PMID: 23032993    Free PMC article.
Treatment with low doses of polyclonal immunoglobulin improves B cell function during immune reconstitution in a murine model.
Ana Barahona Afonso, Lígia Neves Justo, +7 authors, Cristina João.
J Clin Immunol, 2012 Oct 12; 33(2). PMID: 23054339
A New Kid on the Block: IL-10+ Regulatory B Cells and a Possible Role In Psoriasis.
Kamruz Darabi, Rohit Jaiswal, +3 authors, Patricia Witman.
J Pediatr Pharmacol Ther, 2009 Jul 01; 14(3). PMID: 23055903    Free PMC article.
The chicken SLAM family.
Christian Straub, Birgit C Viertlboeck, Thomas W Göbel.
Immunogenetics, 2012 Oct 16; 65(1). PMID: 23064403
Immune complexes isolated from patients with pulmonary tuberculosis modulate the activation and function of normal granulocytes.
P Senbagavalli, J Nancy Hilda, +3 authors, Subash Babu.
Clin Vaccine Immunol, 2012 Oct 27; 19(12). PMID: 23100480    Free PMC article.
Analysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity.
Marion Espéli, Menna R Clatworthy, +5 authors, Kenneth G C Smith.
J Exp Med, 2012 Oct 31; 209(12). PMID: 23109709    Free PMC article.
Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and FcγR signaling.
Christian D Sadik, Nancy D Kim, Yoichiro Iwakura, Andrew D Luster.
Proc Natl Acad Sci U S A, 2012 Nov 01; 109(46). PMID: 23112187    Free PMC article.
Regulation of allograft survival by inhibitory FcγRIIb signaling.
Chris J Callaghan, Thet Su Win, +9 authors, Gavin J Pettigrew.
J Immunol, 2012 Nov 15; 189(12). PMID: 23150718    Free PMC article.
The contribution of allergen-specific IgG to the development of th2-mediated airway inflammation.
Jesse W Williams, Melissa Y Tjota, Anne I Sperling.
J Allergy (Cairo), 2012 Nov 15; 2012. PMID: 23150737    Free PMC article.
Quorum sensing contributes to activated IgM-secreting B cell homeostasis.
Caroline Montaudouin, Marie Anson, +9 authors, António A Freitas.
J Immunol, 2012 Dec 05; 190(1). PMID: 23209322    Free PMC article.
Recombinant human cytomegalovirus (HCMV) RL13 binds human immunoglobulin G Fc.
Mirko Cortese, Stefano Calò, +3 authors, Marcello Merola.
PLoS One, 2012 Dec 12; 7(11). PMID: 23226246    Free PMC article.
Mechanisms of action of CD20 antibodies.
Peter Boross, Jeanette H W Leusen.
Am J Cancer Res, 2012 Dec 12; 2(6). PMID: 23226614    Free PMC article.
ADAM17 cleaves CD16b (FcγRIIIb) in human neutrophils.
Yue Wang, Jianming Wu, +3 authors, Bruce Walcheck.
Biochim Biophys Acta, 2012 Dec 12; 1833(3). PMID: 23228566    Free PMC article.
Antibody orientation at bacterial surfaces is related to invasive infection.
Pontus Nordenfelt, Sofia Waldemarson, +4 authors, Lars Björck.
J Exp Med, 2012 Dec 12; 209(13). PMID: 23230002    Free PMC article.
Proteolysis breaks tolerance toward intact α345(IV) collagen, eliciting novel anti-glomerular basement membrane autoantibodies specific for α345NC1 hexamers.
Florina Olaru, Xu-Ping Wang, +8 authors, Dorin-Bogdan Borza.
J Immunol, 2013 Jan 11; 190(4). PMID: 23303673    Free PMC article.
Macrophage and NK-mediated killing of precursor-B acute lymphoblastic leukemia cells targeted with a-fucosylated anti-CD19 humanized antibodies.
K Matlawska-Wasowska, E Ward, +4 authors, B S Wilson.
Leukemia, 2013 Jan 12; 27(6). PMID: 23307031    Free PMC article.
β(2) integrins inhibit TLR responses by regulating NF-κB pathway and p38 MAPK activation.
Nathan K Yee, Jessica A Hamerman.
Eur J Immunol, 2013 Jan 12; 43(3). PMID: 23310953    Free PMC article.
Serum amyloid P inhibits granulocyte adhesion.
Anu S Maharjan, David Roife, Derrick Brazill, Richard H Gomer.
Fibrogenesis Tissue Repair, 2013 Jan 18; 6(1). PMID: 23324174    Free PMC article.
Application of knockout mouse models to investigate the influence of FcγR on the pharmacokinetics and anti-platelet effects of MWReg30, a monoclonal anti-GPIIb antibody.
Lubna Abuqayyas, Xiaoyan Zhang, Joseph P Balthasar.
Int J Pharm, 2013 Feb 02; 444(1-2). PMID: 23370434    Free PMC article.
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Gordan Lauc, Jennifer E Huffman, +36 authors, Igor Rudan.
PLoS Genet, 2013 Feb 06; 9(1). PMID: 23382691    Free PMC article.
Highly Cited.
In-depth characterization of N-linked oligosaccharides using fluoride-mediated negative ion microfluidic chip LC-MS.
Wenqin Ni, Jonathan Bones, Barry L Karger.
Anal Chem, 2013 Feb 13; 85(6). PMID: 23398125    Free PMC article.
Antibody-DEPENDENT, FcγRI-mediated neutralization of HIV-1 in TZM-bl cells occurs independently of phagocytosis.
Lautaro G Perez, Susan Zolla-Pazner, David C Montefiori.
J Virol, 2013 Feb 15; 87(9). PMID: 23408628    Free PMC article.
Intravenous immunoglobulin therapy: how does IgG modulate the immune system?
Inessa Schwab, Falk Nimmerjahn.
Nat Rev Immunol, 2013 Feb 16; 13(3). PMID: 23411799
Highly Cited. Review.
Combined analysis of genome-wide-linked susceptibility loci to Kawasaki disease in Han Chinese.
Yuanlong Yan, Yongyi Ma, +8 authors, Yuan Yang.
Hum Genet, 2013 Mar 05; 132(6). PMID: 23456091
B cells and their mediators as targets for therapy in solid tumors.
Andrew J Gunderson, Lisa M Coussens.
Exp Cell Res, 2013 Mar 19; 319(11). PMID: 23499742    Free PMC article.
Review.
Toll-like receptor 2 ligands regulate monocyte Fcγ receptor expression and function.
Prexy Shah, Kavin Fatehchand, +6 authors, Jonathan P Butchar.
J Biol Chem, 2013 Mar 19; 288(17). PMID: 23504312    Free PMC article.
Controlling natural killer cell responses: integration of signals for activation and inhibition.
Eric O Long, Hun Sik Kim, +2 authors, Sumati Rajagopalan.
Annu Rev Immunol, 2013 Mar 23; 31. PMID: 23516982    Free PMC article.
Highly Cited. Review.
Natural killer cell mediated antibody-dependent cellular cytotoxicity in tumor immunotherapy with therapeutic antibodies.
Ursula J E Seidel, Patrick Schlegel, Peter Lang.
Front Immunol, 2013 Apr 02; 4. PMID: 23543707    Free PMC article.
Highly Cited.
B-cell targeted therapeutics in clinical development.
Stephan Blüml, Kathleen McKeever, +2 authors, Ronald Herbst.
Arthritis Res Ther, 2013 Apr 10; 15 Suppl 1. PMID: 23566679    Free PMC article.
Review.
New developments in C5a receptor signaling.
J Vidya Sarma, Peter A Ward.
Cell Health Cytoskelet, 2013 Apr 12; 4. PMID: 23576881    Free PMC article.
IL-33-dependent induction of allergic lung inflammation by FcγRIII signaling.
Melissa Y Tjota, Jesse W Williams, +7 authors, Anne I Sperling.
J Clin Invest, 2013 Apr 16; 123(5). PMID: 23585480    Free PMC article.
FCGR2B and FCRLB gene polymorphisms associated with IgA nephropathy.
Xu-jie Zhou, Fa-juan Cheng, +5 authors, Hong Zhang.
PLoS One, 2013 Apr 18; 8(4). PMID: 23593433    Free PMC article.
IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R.
Christopher E Martin, Ester M M van Leeuwen, +3 authors, Charles D Surh.
Blood, 2013 Apr 24; 121(22). PMID: 23610371    Free PMC article.
Human FcγRII cytoplasmic domains differentially influence antibody-mediated dengue virus infection.
Kobporn Boonnak, Bonnie M Slike, Gina C Donofrio, Mary A Marovich.
J Immunol, 2013 Apr 26; 190(11). PMID: 23616574    Free PMC article.
Human Fc receptor-like 5 binds intact IgG via mechanisms distinct from those of Fc receptors.
Andrea Franco, Bazarragchaa Damdinsuren, +4 authors, Mate Tolnay.
J Immunol, 2013 Apr 26; 190(11). PMID: 23616577    Free PMC article.
No evidence that soluble TACI induces signalling via membrane-expressed BAFF and APRIL in myeloid cells.
Josquin Nys, Cristian R Smulski, +6 authors, Pascal Schneider.
PLoS One, 2013 Apr 27; 8(4). PMID: 23620746    Free PMC article.
The B cell helper side of neutrophils.
Andrea Cerutti, Irene Puga, Giuliana Magri.
J Leukoc Biol, 2013 May 01; 94(4). PMID: 23630389    Free PMC article.
Review.
A single-dose PLGA encapsulated protective antigen domain 4 nanoformulation protects mice against Bacillus anthracis spore challenge.
Manish Manish, Amit Rahi, +2 authors, Samer Singh.
PLoS One, 2013 May 03; 8(4). PMID: 23637922    Free PMC article.
Inhibition of HPA-1a alloantibody-mediated platelet destruction by a deglycosylated anti-HPA-1a monoclonal antibody in mice: toward targeted treatment of fetal-alloimmune thrombocytopenia.
Tamam Bakchoul, Andreas Greinacher, +6 authors, Sentot Santoso.
Blood, 2013 May 07; 122(3). PMID: 23645838    Free PMC article.
Targeting natural killer cells to acute myeloid leukemia in vitro with a CD16 x 33 bispecific killer cell engager and ADAM17 inhibition.
Andres Wiernik, Bree Foley, +9 authors, Jeffrey S Miller.
Clin Cancer Res, 2013 May 22; 19(14). PMID: 23690482    Free PMC article.
Highly Cited.
Dengue virus neutralization in cells expressing Fc gamma receptors.
Tanu Chawla, Kuan Rong Chan, +4 authors, Eng Eong Ooi.
PLoS One, 2013 May 30; 8(5). PMID: 23717696    Free PMC article.
Engineered antibody Fc variant with selectively enhanced FcγRIIb binding over both FcγRIIa(R131) and FcγRIIa(H131).
F Mimoto, H Katada, +7 authors, K Hattori.
Protein Eng Des Sel, 2013 Jun 08; 26(10). PMID: 23744091    Free PMC article.
Inflammatory monocytes and Fcγ receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice.
Michaela Seeling, Ulrike Hillenhoff, +4 authors, Falk Nimmerjahn.
Proc Natl Acad Sci U S A, 2013 Jun 12; 110(26). PMID: 23754379    Free PMC article.
T and B lymphocytes in the brains of dogs with concomitant seropositivity to three pathogenic protozoans: Leishmania chagasi, Toxoplasma gondii and Neospora caninum.
Keila Priscilla Sakamoto, Guilherme Dias de Melo, Gisele Fabrino Machado.
BMC Res Notes, 2013 Jun 14; 6. PMID: 23758819    Free PMC article.
Analytical FcRn affinity chromatography for functional characterization of monoclonal antibodies.
Tilman Schlothauer, Petra Rueger, +9 authors, Apollon Papadimitriou.
MAbs, 2013 Jun 15; 5(4). PMID: 23765230    Free PMC article.
The Wnt signaling pathway is involved in the regulation of phagocytosis of virus in Drosophila.
Fei Zhu, Xiaobo Zhang.
Sci Rep, 2013 Jun 26; 3. PMID: 23797713    Free PMC article.
B Cell in Autoimmune Diseases.
Christiane S Hampe.
Scientifica (Cairo), 2012 Jan 01; 2012. PMID: 23807906    Free PMC article.
Membrane-type 6 matrix metalloproteinase regulates the activation-induced downmodulation of CD16 in human primary NK cells.
Giovanna Peruzzi, Laurette Femnou, +4 authors, John E Coligan.
J Immunol, 2013 Jul 16; 191(4). PMID: 23851692    Free PMC article.
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma.
Tyler R Simpson, Fubin Li, +11 authors, Sergio A Quezada.
J Exp Med, 2013 Jul 31; 210(9). PMID: 23897981    Free PMC article.
Highly Cited.
Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies.
Yannick Bulliard, Rose Jolicoeur, +6 authors, Jennifer L Brogdon.
J Exp Med, 2013 Jul 31; 210(9). PMID: 23897982    Free PMC article.
Highly Cited.
Tpl2 kinase regulates FcγR signaling and immune thrombocytopenia in mice.
Irene Kyrmizi, Marianna Ioannou, +3 authors, Ioannis Tassiulas.
J Leukoc Biol, 2013 Jul 31; 94(4). PMID: 23898046    Free PMC article.
Acute inflammation primes myeloid effector cells for anti-inflammatory STAT6 signaling.
Fredrik Wermeling, Robert M Anthony, Frank Brombacher, Jeffrey V Ravetch.
Proc Natl Acad Sci U S A, 2013 Jul 31; 110(33). PMID: 23898202    Free PMC article.
High-dose methylprednisolone pulse therapy upregulated FcγRIIb expression on B cells in primary Sjögren's syndrome patients with thrombocytopenia.
Haifeng Chen, Shiliang Zhou, +3 authors, Lingyun Sun.
Clin Rheumatol, 2013 Aug 07; 32(12). PMID: 23917390
Immunomagnetic enrichment and flow cytometric characterization of mouse microglia.
Supinder S Bedi, Philippa Smith, +2 authors, Charles S Cox.
J Neurosci Methods, 2013 Aug 10; 219(1). PMID: 23928152    Free PMC article.
Lessons for the clinic from rituximab pharmacokinetics and pharmacodynamics.
Josée Golay, Gianpietro Semenzato, +8 authors, Mario Regazzi.
MAbs, 2013 Aug 13; 5(6). PMID: 23933992    Free PMC article.
Review.
Clinical presentation, pathogenesis, diagnosis, and treatment of epidermolysis bullosa acquisita.
Ralf J Ludwig.
ISRN Dermatol, 2013 Aug 21; 2013. PMID: 23956869    Free PMC article.
Fc-gamma receptor polymorphisms as predictive and prognostic factors in patients receiving oncolytic adenovirus treatment.
Mari Hirvinen, Raita Heiskanen, +6 authors, Akseli Hemminki.
J Transl Med, 2013 Aug 24; 11. PMID: 23965133    Free PMC article.
Ankylosing spondylitis: from cells to genes.
José Francisco Zambrano-Zaragoza, Juan Manuel Agraz-Cibrian, +2 authors, Norberto Vibanco-Pérez.
Int J Inflam, 2013 Aug 24; 2013. PMID: 23970995    Free PMC article.
Fcγ receptors enable anticancer action of proapoptotic and immune-modulatory antibodies.
Jeong M Kim, Avi Ashkenazi.
J Exp Med, 2013 Aug 28; 210(9). PMID: 23980122    Free PMC article.
Review.
Involvement of antibody-dependent cell-mediated cytotoxicity in inflammatory demyelination in a mouse model of neuromyelitis optica.
Julien Ratelade, Nithi Asavapanumas, +3 authors, A S Verkman.
Acta Neuropathol, 2013 Sep 03; 126(5). PMID: 23995423    Free PMC article.
Intravenous immunoglobulin-mediated immunosuppression and the development of an IVIG substitute.
Miglena G Prabagar, Hyeong-jwa Choi, +2 authors, Young-Sun Kang.
Clin Exp Med, 2013 Sep 03; 14(4). PMID: 23996469
Review.
Molecular basis for downregulation of C5a-mediated inflammation by IgG1 immune complexes in allergy and asthma.
Manoj Kumar Pandey.
Curr Allergy Asthma Rep, 2013 Sep 10; 13(6). PMID: 24013944
Review.
No Association between FC γ R3B Copy Number Variation and Susceptibility to Biopsy-Proven Giant Cell Arteritis.
Emma Dunstan, Sue Lester, +4 authors, Catherine L Hill.
Arthritis, 2013 Sep 13; 2013. PMID: 24027635    Free PMC article.
To fuse or not to fuse: what is your purpose?
Mark R Bell, Mark J Engleka, Asim Malik, James E Strickler.
Protein Sci, 2013 Sep 17; 22(11). PMID: 24038604    Free PMC article.
Review.
Comparative efficiency of HIV-1-infected T cell killing by NK cells, monocytes and neutrophils.
Adjoa Smalls-Mantey, Mark Connors, Quentin J Sattentau.
PLoS One, 2013 Sep 17; 8(9). PMID: 24040353    Free PMC article.
RON receptor tyrosine kinase, a negative regulator of inflammation, is decreased during simian immunodeficiency virus-associated central nervous system disease.
Daniele C Cary, Janice E Clements, Andrew J Henderson.
J Immunol, 2013 Sep 18; 191(8). PMID: 24043899    Free PMC article.
Glycoepitopes of staphylococcal wall teichoic acid govern complement-mediated opsonophagocytosis via human serum antibody and mannose-binding lectin.
Kenji Kurokawa, Dong-Jun Jung, +12 authors, Bok Luel Lee.
J Biol Chem, 2013 Sep 21; 288(43). PMID: 24045948    Free PMC article.
B cell-regulated immune responses in tumor models and cancer patients.
Carlo Fremd, Florian Schuetz, +2 authors, Christoph Domschke.
Oncoimmunology, 2013 Sep 28; 2(7). PMID: 24073382    Free PMC article.
Review.
Retargeting T cells for HER2-positive tumor killing by a bispecific Fv-Fc antibody.
Lei Wang, Yanran He, +7 authors, Bin Gao.
PLoS One, 2013 Oct 03; 8(9). PMID: 24086580    Free PMC article.
Meningococcal disease and the complement system.
Lisa A Lewis, Sanjay Ram.
Virulence, 2013 Oct 10; 5(1). PMID: 24104403    Free PMC article.
Review.
Exocytosis acts as a modulator of the ILT4-mediated inhibition of neutrophil functions.
Jeremy Baudhuin, Julie Migraine, +4 authors, Benoit Favier.
Proc Natl Acad Sci U S A, 2013 Oct 18; 110(44). PMID: 24133137    Free PMC article.
Investigating monoclonal antibody aggregation using a combination of H/DX-MS and other biophysical measurements.
Roxana E Iacob, George M Bou-Assaf, +3 authors, Damian Houde.
J Pharm Sci, 2013 Oct 19; 102(12). PMID: 24136070    Free PMC article.
The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus.
Rachael Keating, Tomer Hertz, +12 authors, Maureen A McGargill.
Nat Immunol, 2013 Oct 22; 14(12). PMID: 24141387    Free PMC article.
Highly Cited.
Opportunities to exploit non-neutralizing HIV-specific antibody activity.
Margaret E Ackerman, Galit Alter.
Curr HIV Res, 2013 Nov 07; 11(5). PMID: 24191934    Free PMC article.
Review.
Fc receptor-mediated immune responses: new tools but increased complexity in HIV prevention.
Diego A Vargas-Inchaustegui, Marjorie Robert-Guroff.
Curr HIV Res, 2013 Nov 07; 11(5). PMID: 24191937    Free PMC article.
Epitope specificity of human immunodeficiency virus-1 antibody dependent cellular cytotoxicity [ADCC] responses.
Justin Pollara, Mattia Bonsignori, +3 authors, Guido Ferrari.
Curr HIV Res, 2013 Nov 07; 11(5). PMID: 24191939    Free PMC article.
Review.
Antitumor activities of agonistic anti-TNFR antibodies require differential FcγRIIB coengagement in vivo.
Fubin Li, Jeffrey V Ravetch.
Proc Natl Acad Sci U S A, 2013 Nov 13; 110(48). PMID: 24218606    Free PMC article.
HLA-DQA1 and PLA2R1 polymorphisms and risk of idiopathic membranous nephropathy.
Gemma Bullich, José Ballarín, +6 authors, Elisabet Ars.
Clin J Am Soc Nephrol, 2013 Nov 23; 9(2). PMID: 24262501    Free PMC article.
Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease.
Zsuzsanna Tucsek, Peter Toth, +7 authors, Anna Csiszar.
J Gerontol A Biol Sci Med Sci, 2013 Nov 26; 69(10). PMID: 24269929    Free PMC article.
Highly Cited.
Enhancement of anti-tumor CD8 immunity by IgG1-mediated targeting of Fc receptors.
Scott N Furlan, Rajakumar Mandraju, +6 authors, Chandrashekhar Pasare.
MAbs, 2013 Nov 29; 6(1). PMID: 24284965    Free PMC article.
Cutting edge: Expression of FcγRIIB tempers memory CD8 T cell function in vivo.
Gabriel R Starbeck-Miller, Vladimir P Badovinac, Daniel L Barber, John T Harty.
J Immunol, 2013 Nov 29; 192(1). PMID: 24285839    Free PMC article.
Asymmetrical Fc engineering greatly enhances antibody-dependent cellular cytotoxicity (ADCC) effector function and stability of the modified antibodies.
Zhi Liu, Kannan Gunasekaran, +10 authors, Wei Yan.
J Biol Chem, 2013 Dec 07; 289(6). PMID: 24311787    Free PMC article.
Liquid-liquid diffusion crystallization improves the X-ray diffraction of EndoS, an endo-β-N-acetylglucosaminidase from Streptococcus pyogenes with activity on human IgG.
Beatriz Trastoy, Joseph V Lomino, Lai Xi Wang, Eric J Sundberg.
Acta Crystallogr Sect F Struct Biol Cryst Commun, 2013 Dec 10; 69(Pt 12). PMID: 24316841    Free PMC article.
Early IFN-gamma production after YF 17D vaccine virus immunization in mice and its association with adaptive immune responses.
Patrícia C C Neves, Juliana R Santos, +2 authors, Ricardo Galler.
PLoS One, 2013 Dec 11; 8(12). PMID: 24324734    Free PMC article.
Glycosylation of immunoglobulin g: role of genetic and epigenetic influences.
Cristina Menni, Toma Keser, +11 authors, Ana M Valdes.
PLoS One, 2013 Dec 11; 8(12). PMID: 24324808    Free PMC article.
Fcγ receptor upregulation is associated with immune complex inflammation in the mouse retina and early age-related macular degeneration.
Salome Murinello, Robert F Mullins, +2 authors, Jessica L Teeling.
Invest Ophthalmol Vis Sci, 2013 Dec 18; 55(1). PMID: 24334446    Free PMC article.
Genetic dissection of dendritic cell homeostasis and function: lessons from cell type-specific gene ablation.
Peer W F Karmaus, Hongbo Chi.
Cell Mol Life Sci, 2013 Dec 25; 71(10). PMID: 24366237    Free PMC article.
Review.
Recombinant IgG2a Fc (M045) multimers effectively suppress experimental autoimmune myasthenia gravis.
Muthusamy Thiruppathi, Jian Rong Sheng, +2 authors, Matthew N Meriggioli.
J Autoimmun, 2014 Jan 07; 52. PMID: 24388113    Free PMC article.
Yersinia pestis: mechanisms of entry into and resistance to the host cell.
Yuehua Ke, Zeliang Chen, Ruifu Yang.
Front Cell Infect Microbiol, 2014 Jan 09; 3. PMID: 24400226    Free PMC article.
Review.
Human IgG Fc domain engineering enhances antitoxin neutralizing antibody activity.
Stylianos Bournazos, Siu-Kei Chow, +2 authors, Jeffrey V Ravetch.
J Clin Invest, 2014 Jan 10; 124(2). PMID: 24401277    Free PMC article.
Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo.
David J DiLillo, Gene S Tan, Peter Palese, Jeffrey V Ravetch.
Nat Med, 2014 Jan 15; 20(2). PMID: 24412922    Free PMC article.
Highly Cited.
Chemical and chemoenzymatic synthesis of glycoproteins for deciphering functions.
Lai-Xi Wang, Mohammed N Amin.
Chem Biol, 2014 Jan 21; 21(1). PMID: 24439206    Free PMC article.
Review.
CD19 and CD32b differentially regulate human B cell responsiveness.
Jodi L Karnell, Nazzareno Dimasi, +7 authors, Rachel Ettinger.
J Immunol, 2014 Jan 21; 192(4). PMID: 24442430    Free PMC article.
The function of Fcγ receptors in dendritic cells and macrophages.
Martin Guilliams, Pierre Bruhns, +2 authors, Bart N Lambrecht.
Nat Rev Immunol, 2014 Jan 22; 14(2). PMID: 24445665
Highly Cited. Review.
Whole Pichia pastoris yeast expressing measles virus nucleoprotein as a production and delivery system to multimerize Plasmodium antigens.
Daria Jacob, Claude Ruffie, +11 authors, Monica Sala.
PLoS One, 2014 Jan 30; 9(1). PMID: 24475165    Free PMC article.
Increasing FcγRIIa affinity of an FcγRIII-optimized anti-EGFR antibody restores neutrophil-mediated cytotoxicity.
Stefanie Derer, Pia Glorius, +7 authors, Matthias Peipp.
MAbs, 2014 Feb 05; 6(2). PMID: 24492248    Free PMC article.
Effects of altered FcγR binding on antibody pharmacokinetics in cynomolgus monkeys.
Maya K Leabman, Y Gloria Meng, +3 authors, Suhasini Iyer.
MAbs, 2014 Feb 05; 5(6). PMID: 24492343    Free PMC article.
Respiratory syncytial virus persistence in macrophages upregulates Fcgamma receptors expression.
Jorge Gaona, Carlos Santiago-Olivares, Enrique Ortega, Beatriz Gómez.
Viruses, 2014 Feb 11; 6(2). PMID: 24509813    Free PMC article.
The biology of NK cells and their receptors affects clinical outcomes after hematopoietic cell transplantation (HCT).
Bree Foley, Martin Felices, +3 authors, Jeffrey S Miller.
Immunol Rev, 2014 Feb 13; 258(1). PMID: 24517425    Free PMC article.
Review.
Fcγ receptor-mediated inflammation inhibits axon regeneration.
Gang Zhang, Nataliia Bogdanova, +4 authors, Kazim A Sheikh.
PLoS One, 2014 Feb 14; 9(2). PMID: 24523933    Free PMC article.
Structural insights on the role of antibodies in HIV-1 vaccine and therapy.
Anthony P West, Louise Scharf, +3 authors, Michel C Nussenzweig.
Cell, 2014 Feb 18; 156(4). PMID: 24529371    Free PMC article.
Highly Cited. Review.
An Fc domain protein-small molecule conjugate as an enhanced immunomodulator.
Meng-Jung Chiang, Marc A Holbert, +14 authors, Philip A Cole.
J Am Chem Soc, 2014 Feb 19; 136(9). PMID: 24533830    Free PMC article.
Inhibitory Fcγ receptor is required for the maintenance of tolerance through distinct mechanisms.
Fubin Li, Patrick Smith, Jeffrey V Ravetch.
J Immunol, 2014 Feb 25; 192(7). PMID: 24563255    Free PMC article.
Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA.
Juan Carlos Almagro, Gary L Gilliland, +21 authors, Kai Y Xu.
MAbs, 2014 Mar 05; 6(3). PMID: 24589717    Free PMC article.
Direct neutralization of type III effector translocation by the variable region of a monoclonal antibody to Yersinia pestis LcrV.
Maya I Ivanov, Jim Hill, James B Bliska.
Clin Vaccine Immunol, 2014 Mar 07; 21(5). PMID: 24599533    Free PMC article.
Current and Potential Uses of Immunocytokines as Cancer Immunotherapy.
Paul M Sondel, Stephen D Gillies.
Antibodies (Basel), 2012 Jul 04; 1(2). PMID: 24634778    Free PMC article.
Natural autoantibodies to Fcγ receptors in intravenous immunoglobulins.
Hicham Bouhlal, Denis Martinvalet, +5 authors, Srini V Kaveri.
J Clin Immunol, 2014 Apr 01; 34 Suppl 1. PMID: 24682714
Persistent lung inflammation and fibrosis in serum amyloid P component (APCs-/-) knockout mice.
Darrell Pilling, Richard H Gomer.
PLoS One, 2014 Apr 04; 9(4). PMID: 24695531    Free PMC article.
Chemoenzymatic Fc glycosylation via engineered aldehyde tags.
Elizabeth L Smith, John P Giddens, +3 authors, Carolyn R Bertozzi.
Bioconjug Chem, 2014 Apr 08; 25(4). PMID: 24702330    Free PMC article.
Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering.
Limin Shang, Bruno Daubeuf, +21 authors, Greg Elson.
J Biol Chem, 2014 Apr 17; 289(22). PMID: 24737331    Free PMC article.
Antigen cross-presentation of immune complexes.
Barbara Platzer, Madeleine Stout, Edda Fiebiger.
Front Immunol, 2014 Apr 20; 5. PMID: 24744762    Free PMC article.
Review.
Development of a cell-based assay measuring the activation of FcγRIIa for the characterization of therapeutic monoclonal antibodies.
Minoru Tada, Akiko Ishii-Watabe, Takuo Suzuki, Nana Kawasaki.
PLoS One, 2014 Apr 23; 9(4). PMID: 24752341    Free PMC article.
Inhibition of murine fibrocyte differentiation by cross-linked IgG is dependent on FcγRI.
Darrell Pilling, Jeffrey R Crawford, J Sjef Verbeek, Richard H Gomer.
J Leukoc Biol, 2014 Apr 23; 96(2). PMID: 24752483    Free PMC article.
Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies.
Beatriz Trastoy, Joseph V Lomino, +8 authors, Eric J Sundberg.
Proc Natl Acad Sci U S A, 2014 Apr 23; 111(18). PMID: 24753590    Free PMC article.
Fcγ receptor III and Fcγ receptor IV on macrophages drive autoimmune valvular carditis in mice.
Patricia M Hobday, Jennifer L Auger, +3 authors, Bryce A Binstadt.
Arthritis Rheumatol, 2014 Apr 24; 66(4). PMID: 24757138    Free PMC article.
Targeting B cells and autoantibodies in the therapy of autoimmune diseases.
Daniela Kao, Anja Lux, Inessa Schwab, Falk Nimmerjahn.
Semin Immunopathol, 2014 Apr 30; 36(3). PMID: 24777745
Review.
Antibody-mediated enhancement of parvovirus B19 uptake into endothelial cells mediated by a receptor for complement factor C1q.
Kristina von Kietzell, Tanja Pozzuto, +3 authors, Stefan Weger.
J Virol, 2014 May 09; 88(14). PMID: 24807719    Free PMC article.
Fc receptors for immunoglobulins and their appearance during vertebrate evolution.
Srinivas Akula, Sayran Mohammadamin, Lars Hellman.
PLoS One, 2014 May 13; 9(5). PMID: 24816777    Free PMC article.
Suppression of innate and adaptive B cell activation pathways by antibody coengagement of FcγRIIb and CD19.
Dániel Szili, Marcell Cserhalmi, +3 authors, Gabriella Sármay.
MAbs, 2014 May 16; 6(4). PMID: 24828435    Free PMC article.
Single-domain antibodies targeting neuraminidase protect against an H5N1 influenza virus challenge.
Francisco Miguel Cardoso, Lorena Itatí Ibañez, +9 authors, Xavier Saelens.
J Virol, 2014 May 16; 88(15). PMID: 24829341    Free PMC article.
Primer on tumor immunology and cancer immunotherapy.
Timothy J Harris, Charles G Drake.
J Immunother Cancer, 2013 Jan 01; 1. PMID: 24829749    Free PMC article.
Review.
Role of Fc-mediated antibody function in protective immunity against HIV-1.
George K Lewis.
Immunology, 2014 May 21; 142(1). PMID: 24843871    Free PMC article.
Review.
B cells and humoral immunity in atherosclerosis.
Dimitrios Tsiantoulas, Cody J Diehl, Joseph L Witztum, Christoph J Binder.
Circ Res, 2014 May 24; 114(11). PMID: 24855199    Free PMC article.
Highly Cited. Review.
The Fab conformations in the solution structure of human immunoglobulin G4 (IgG4) restrict access to its Fc region: implications for functional activity.
Lucy E Rayner, Gar Kay Hui, +3 authors, Stephen J Perkins.
J Biol Chem, 2014 May 31; 289(30). PMID: 24876381    Free PMC article.
Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirus.
Ming Shum Yip, Nancy Hiu Lan Leung, +6 authors, Martial Jaume.
Virol J, 2014 Jun 03; 11. PMID: 24885320    Free PMC article.
Investigating perturbed pathway modules from gene expression data via structural equation models.
Daniele Pepe, Mario Grassi.
BMC Bioinformatics, 2014 Jun 03; 15. PMID: 24885496    Free PMC article.
Glycans - the third revolution in evolution.
Gordan Lauc, Jasminka Krištić, Vlatka Zoldoš.
Front Genet, 2014 Jun 07; 5. PMID: 24904645    Free PMC article.
Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies.
Caitlin Gillis, Aurélie Gouel-Chéron, Friederike Jönsson, Pierre Bruhns.
Front Immunol, 2014 Jun 10; 5. PMID: 24910634    Free PMC article.
Review.
Actin cytoskeleton reorganization by Syk regulates Fcγ receptor responsiveness by increasing its lateral mobility and clustering.
Valentin Jaumouillé, Yoav Farkash, +3 authors, Sergio Grinstein.
Dev Cell, 2014 Jun 11; 29(5). PMID: 24914558    Free PMC article.
Neurobiology of microglial action in CNS injuries: receptor-mediated signaling mechanisms and functional roles.
Xiaoming Hu, Anthony K F Liou, +7 authors, Jun Chen.
Prog Neurobiol, 2014 Jun 14; 119-120. PMID: 24923657    Free PMC article.
Review.
Dual role for Fcγ receptors in host defense and disease in Borrelia burgdorferi-infected mice.
Alexia A Belperron, Nengyin Liu, Carmen J Booth, Linda K Bockenstedt.
Front Cell Infect Microbiol, 2014 Jun 27; 4. PMID: 24967215    Free PMC article.
Dengue virus infection induces expansion of a CD14(+)CD16(+) monocyte population that stimulates plasmablast differentiation.
Marcin Kwissa, Helder I Nakaya, +8 authors, Bali Pulendran.
Cell Host Microbe, 2014 Jul 02; 16(1). PMID: 24981333    Free PMC article.
Highly Cited.
Association studies of Fcγ receptor polymorphisms with outcome in HER2+ breast cancer patients treated with trastuzumab in NCCTG (Alliance) Trial N9831.
Nadine Norton, Rebecca M Olson, +5 authors, Edith A Perez.
Cancer Immunol Res, 2014 Jul 06; 2(10). PMID: 24989892    Free PMC article.
Enhanced auto-antibody production and Mott cell formation in FcμR-deficient autoimmune mice.
Kazuhito Honjo, Yoshiki Kubagawa, +5 authors, Hiromi Kubagawa.
Int Immunol, 2014 Jul 06; 26(12). PMID: 24994818    Free PMC article.
Prolonged antigen presentation by immune complex-binding dendritic cells programs the proliferative capacity of memory CD8 T cells.
Beatriz León, André Ballesteros-Tato, Troy D Randall, Frances E Lund.
J Exp Med, 2014 Jul 09; 211(8). PMID: 25002751    Free PMC article.
Defunctioning polymorphism in the immunoglobulin G inhibitory receptor (FcγRIIB-T/T232) does not impact on kidney transplant or recipient survival.
Menna R Clatworthy, Rebeccah J Matthews, +3 authors, Kenneth G C Smith.
Transplantation, 2014 Jul 16; 98(3). PMID: 25022320    Free PMC article.
Distinct Fcγ receptors mediate the effect of serum amyloid p on neutrophil adhesion and fibrocyte differentiation.
Nehemiah Cox, Darrell Pilling, Richard H Gomer.
J Immunol, 2014 Jul 16; 193(4). PMID: 25024390    Free PMC article.
Scavenger receptor function of mouse Fcγ receptor III contributes to progression of atherosclerosis in apolipoprotein E hyperlipidemic mice.
Xinmei Zhu, Hang Pong Ng, +4 authors, Shanmugam Nagarajan.
J Immunol, 2014 Jul 20; 193(5). PMID: 25038257    Free PMC article.
Independent evolution of Fc- and Fab-mediated HIV-1-specific antiviral antibody activity following acute infection.
Anne-Sophie Dugast, Leonidas Stamatatos, +8 authors, Galit Alter.
Eur J Immunol, 2014 Jul 22; 44(10). PMID: 25043633    Free PMC article.
Phenotypic expression in human monocyte-derived interleukin-4-induced foreign body giant cells and macrophages in vitro: dependence on material surface properties.
Amy K McNally, James M Anderson.
J Biomed Mater Res A, 2014 Jul 22; 103(4). PMID: 25045023    Free PMC article.
Type I and type II Fc receptors regulate innate and adaptive immunity.
Andrew Pincetic, Stylianos Bournazos, +5 authors, Jeffrey V Ravetch.
Nat Immunol, 2014 Jul 22; 15(8). PMID: 25045879    Free PMC article.
Highly Cited. Review.
CD64 expression is increased in patients with severe acute pancreatitis: clinical significance.
Hao Zhang, Xian-Long Ling, +5 authors, Shi-Ming Yang.
Gut Liver, 2014 Jul 30; 8(4). PMID: 25071912    Free PMC article.
Silencing Bruton's tyrosine kinase in alveolar neutrophils protects mice from LPS/immune complex-induced acute lung injury.
Agnieszka Krupa, Marek Fol, +10 authors, Anna K Kurdowska.
Am J Physiol Lung Cell Mol Physiol, 2014 Aug 03; 307(6). PMID: 25085625    Free PMC article.
FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial.
Shuying S Li, Peter B Gilbert, +31 authors, Daniel E Geraghty.
J Clin Invest, 2014 Aug 12; 124(9). PMID: 25105367    Free PMC article.
Highly Cited.
Human gene copy number variation and infectious disease.
Edward J Hollox, Boon-Peng Hoh.
Hum Genet, 2014 Aug 12; 133(10). PMID: 25110110
Review.
Enhanced neonatal Fc receptor function improves protection against primate SHIV infection.
Sung-Youl Ko, Amarendra Pegu, +18 authors, Gary J Nabel.
Nature, 2014 Aug 15; 514(7524). PMID: 25119033    Free PMC article.
Highly Cited.
Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice.
Ariel Halper-Stromberg, Ching-Lan Lu, +13 authors, Michel C Nussenzweig.
Cell, 2014 Aug 19; 158(5). PMID: 25131989    Free PMC article.
Highly Cited.
Atheroprotective immunization with malondialdehyde-modified LDL is hapten specific and dependent on advanced MDA adducts: implications for development of an atheroprotective vaccine.
Ayelet Gonen, Lotte F Hansen, +12 authors, Karsten Hartvigsen.
J Lipid Res, 2014 Aug 22; 55(10). PMID: 25143462    Free PMC article.
Delineating the importance of serum opsonins and the bacterial capsule in affecting the uptake and killing of Burkholderia pseudomallei by murine neutrophils and macrophages.
Minal Mulye, Michael P Bechill, +3 authors, R Mark Wooten.
PLoS Negl Trop Dis, 2014 Aug 22; 8(8). PMID: 25144195    Free PMC article.
Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function.
Amy W Chung, Max Crispin, +8 authors, Galit Alter.
AIDS, 2014 Aug 28; 28(17). PMID: 25160934    Free PMC article.
New roles for Fc receptors in neurodegeneration-the impact on Immunotherapy for Alzheimer's Disease.
James P Fuller, Jeffrey B Stavenhagen, Jessica L Teeling.
Front Neurosci, 2014 Sep 06; 8. PMID: 25191216    Free PMC article.
Review.
Age-related macular degeneration in the aspect of chronic low-grade inflammation (pathophysiological parainflammation).
Małgorzata Nita, Andrzej Grzybowski, Francisco J Ascaso, Valentín Huerva.
Mediators Inflamm, 2014 Sep 13; 2014. PMID: 25214719    Free PMC article.
Functions of Antibodies.
Donald N Forthal.
Microbiol Spectr, 2014 Sep 13; 2(4). PMID: 25215264    Free PMC article.
Universal antibody conjugation to nanoparticles using the Fcγ receptor I (FcγRI): quantitative profiling of membrane biomarkers.
Chloe Kim, Justin F Galloway, Kwan Hyi Lee, Peter C Searson.
Bioconjug Chem, 2014 Sep 13; 25(10). PMID: 25215471    Free PMC article.
The Role of FcRn in Antigen Presentation.
Kristi Baker, Timo Rath, Michal Pyzik, Richard S Blumberg.
Front Immunol, 2014 Sep 16; 5. PMID: 25221553    Free PMC article.
Review.
Therapeutic blockade of LIGHT interaction with herpesvirus entry mediator and lymphotoxin β receptor attenuates in vivo cytotoxic allogeneic responses.
Maria-Luisa del Rio, Carlos Fernandez-Renedo, +6 authors, Jose-Ignacio Rodriguez-Barbosa.
Transplantation, 2014 Sep 17; 98(11). PMID: 25226173    Free PMC article.
Maternal antibodies: clinical significance, mechanism of interference with immune responses, and possible vaccination strategies.
Stefan Niewiesk.
Front Immunol, 2014 Oct 04; 5. PMID: 25278941    Free PMC article.
Highly Cited. Review.
CMV-encoded Fcγ receptors: modulators at the interface of innate and adaptive immunity.
Eugenia Corrales-Aguilar, Katja Hoffmann, Hartmut Hengel.
Semin Immunopathol, 2014 Oct 08; 36(6). PMID: 25288477
Review.
The mechanism of phagocytosis: two stages of engulfment.
David M Richards, Robert G Endres.
Biophys J, 2014 Oct 09; 107(7). PMID: 25296306    Free PMC article.
Role of B cells and antibodies in acquired immunity against Mycobacterium tuberculosis.
Jacqueline M Achkar, John Chan, Arturo Casadevall.
Cold Spring Harb Perspect Med, 2014 Oct 11; 5(3). PMID: 25301934    Free PMC article.
Review.
The Amazing Transglycosylation Activity of Endo-β-N-acetylglucosaminidases.
Lai-Xi Wang.
Trends Glycosci Glycotechnol, 2011 Jan 01; 23(129). PMID: 25309039    Free PMC article.
Immune complexes inhibit IL-1 secretion and inflammasome activation.
John R Janczy, Ceren Ciraci, +4 authors, Fayyaz S Sutterwala.
J Immunol, 2014 Oct 17; 193(10). PMID: 25320279    Free PMC article.
Dichotomy in FcγRIIB deficiency and autoimmune-prone SLAM haplotype clarifies the roles of the Fc receptor in development of autoantibodies and glomerulonephritis.
Yasuyoshi Kanari, Akiko Sugahara-Tobinai, +4 authors, Toshiyuki Takai.
BMC Immunol, 2014 Oct 24; 15. PMID: 25339546    Free PMC article.
Fc gamma receptor IIb on GM-CSF macrophages controls immune complex mediated inhibition of inflammatory signals.
Kim C M Santegoets, Mark H Wenink, Wim B van den Berg, Timothy R D J Radstake.
PLoS One, 2014 Oct 24; 9(10). PMID: 25340460    Free PMC article.
Development of non-viral vehicles for targeted gene transfer into microglia via the integrin receptor CD11b.
Markus Smolny, Mary-Louise Rogers, +2 authors, Martin J Stebbing.
Front Mol Neurosci, 2014 Oct 28; 7. PMID: 25346658    Free PMC article.
IgG1 protects against renal disease in a mouse model of cryoglobulinaemia.
Richard T Strait, Monica T Posgai, +11 authors, Fred D Finkelman.
Nature, 2014 Nov 05; 517(7535). PMID: 25363774    Free PMC article.
IgG receptor FcγRIIB plays a key role in obesity-induced hypertension.
Nathan C Sundgren, Wanpen Vongpatanasin, +5 authors, Philip W Shaul.
Hypertension, 2014 Nov 05; 65(2). PMID: 25368023    Free PMC article.
Investigating the interaction between the neonatal Fc receptor and monoclonal antibody variants by hydrogen/deuterium exchange mass spectrometry.
Pernille Foged Jensen, Vincent Larraillet, +3 authors, Kasper D Rand.
Mol Cell Proteomics, 2014 Nov 08; 14(1). PMID: 25378534    Free PMC article.
Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages.
Lisa T C Vogelpoel, Ivo S Hansen, +8 authors, Jeroen den Dunnen.
Nat Commun, 2014 Nov 14; 5. PMID: 25392121    Free PMC article.
Antibody-dependent enhancement infection facilitates dengue virus-regulated signaling of IL-10 production in monocytes.
Tsung-Ting Tsai, Yi-Jui Chuang, +5 authors, Chiou-Feng Lin.
PLoS Negl Trop Dis, 2014 Nov 21; 8(11). PMID: 25412261    Free PMC article.
Genetic Susceptibility to ANCA-Associated Vasculitis: State of the Art.
Francesco Bonatti, Michele Reina, Tauro Maria Neri, Davide Martorana.
Front Immunol, 2014 Dec 03; 5. PMID: 25452756    Free PMC article.
Review.
The role of B cells and humoral immunity in Mycobacterium tuberculosis infection.
John Chan, Simren Mehta, +4 authors, JoAnne Flynn.
Semin Immunol, 2014 Dec 03; 26(6). PMID: 25458990    Free PMC article.
Review.
HIV-1 CD4-induced (CD4i) gp120 epitope vaccines promote B and T-cell responses that contribute to reduced viral loads in rhesus macaques.
Michael A Thomas, Iskra Tuero, +13 authors, Marjorie Robert-Guroff.
Virology, 2014 Dec 03; 471-473. PMID: 25461534    Free PMC article.
Clinical severity of visceral leishmaniasis is associated with changes in immunoglobulin g fc N-glycosylation.
Luiz Gustavo Gardinassi, Viktoria Dotz, +8 authors, Isabel Kinney Ferreira de Miranda Santos.
mBio, 2014 Dec 04; 5(6). PMID: 25467439    Free PMC article.
FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis.
Menna R Clatworthy, Sarah K Harford, Rebeccah J Mathews, Kenneth G C Smith.
Proc Natl Acad Sci U S A, 2014 Dec 06; 111(50). PMID: 25475856    Free PMC article.
Gut microbiota elicits a protective immune response against malaria transmission.
Bahtiyar Yilmaz, Silvia Portugal, +12 authors, Miguel P Soares.
Cell, 2014 Dec 07; 159(6). PMID: 25480293    Free PMC article.
Highly Cited.
IgG4 can induce an M2-like phenotype in human monocyte-derived macrophages through FcγRI.
Jennifer F A Swisher, Devin A Haddad, +2 authors, Gerald M Feldman.
MAbs, 2014 Dec 09; 6(6). PMID: 25484046    Free PMC article.
A general strategy for generating intact, full-length IgG antibodies that penetrate into the cytosol of living cells.
Dong-Ki Choi, Jeomil Bae, +3 authors, Yong-Sung Kim.
MAbs, 2014 Dec 09; 6(6). PMID: 25484049    Free PMC article.
Protein A-neutralizing monoclonal antibody protects neonatal mice against Staphylococcus aureus.
Vilasack Thammavongsa, Sabine Rauch, +2 authors, Olaf Schneewind.
Vaccine, 2014 Dec 10; 33(4). PMID: 25488332    Free PMC article.
Detection of true IgE-expressing mouse B lineage cells.
Michael P Gallagher, Akritee Shrestha, Jennifer M Magee, Duane R Wesemann.
J Vis Exp, 2014 Dec 10; (94). PMID: 25490087    Free PMC article.
Chemically synthesized molecules with the targeting and effector functions of antibodies.
Patrick J McEnaney, Kelly J Fitzgerald, +5 authors, David A Spiegel.
J Am Chem Soc, 2014 Dec 17; 136(52). PMID: 25514603    Free PMC article.
Monomeric IgG1 Fc molecules displaying unique Fc receptor interactions that are exploitable to treat inflammation-mediated diseases.
Tianlei Ying, Yang Feng, +2 authors, Dimiter S Dimitrov.
MAbs, 2014 Dec 18; 6(5). PMID: 25517305    Free PMC article.
A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies.
Jan Stracke, Thomas Emrich, +11 authors, Apollon Papadimitriou.
MAbs, 2014 Dec 18; 6(5). PMID: 25517308    Free PMC article.
A monoclonal antibody against hinge-cleaved IgG restores effector function to proteolytically-inactivated IgGs in vitro and in vivo.
Randall J Brezski, Michelle Kinder, +9 authors, Robert E Jordan.
MAbs, 2014 Dec 18; 6(5). PMID: 25517311    Free PMC article.
Fc-dependent mechanisms of action: roles of FcγR and FcRn.
T Kuijpers.
Clin Exp Immunol, 2014 Dec 30; 178 Suppl 1. PMID: 25546775    Free PMC article.
De-functioning polymorphism in the inhibitory receptor FcγRIIB does not impact upon kidney allograft survival.
M R Clatworthy, R Matthews, +3 authors, K G C Smith.
Clin Exp Immunol, 2014 Dec 30; 178 Suppl 1. PMID: 25546804    Free PMC article.
Rational clinical trial design for antibody mediated renal allograft injury.
Shaifali Sandal, Martin S Zand.
Front Biosci (Landmark Ed), 2015 Jan 02; 20(4). PMID: 25553476    Free PMC article.
Review.
Induced expression of FcγRIIIa (CD16a) on CD4+ T cells triggers generation of IFN-γhigh subset.
Anil K Chauhan, Chen Chen, Terry L Moore, Richard J DiPaolo.
J Biol Chem, 2015 Jan 06; 290(8). PMID: 25556651    Free PMC article.
The high-affinity human IgG receptor Fc gamma receptor I (FcγRI) is not associated with vascular leakage of dengue.
Zaiharina Mohamad Zamberi, Zuraihan Zakaria, +6 authors, Hoh Boon Peng.
J Negat Results Biomed, 2015 Jan 09; 14. PMID: 25566870    Free PMC article.
Requirement for Fc effector mechanisms in the APOBEC3/Rfv3-dependent neutralizing antibody response.
Kalani Halemano, Bradley S Barrett, +2 authors, Mario L Santiago.
J Virol, 2015 Jan 16; 89(7). PMID: 25589647    Free PMC article.
Fcγ receptors and ligands and cardiovascular disease.
Keiji Tanigaki, Nathan Sundgren, +3 authors, Philip W Shaul.
Circ Res, 2015 Jan 17; 116(2). PMID: 25593280    Free PMC article.
Review.
A comparison of assays for accurate copy number measurement of the low-affinity Fc gamma receptor genes FCGR3A and FCGR3B.
Umi Shakina Haridan, Umairah Mokhtar, +11 authors, Hoh Boon Peng.
PLoS One, 2015 Jan 17; 10(1). PMID: 25594501    Free PMC article.
Unique ligand-binding property of the human IgM Fc receptor.
Kazuhito Honjo, Yoshiki Kubagawa, John F Kearney, Hiromi Kubagawa.
J Immunol, 2015 Jan 21; 194(4). PMID: 25601920    Free PMC article.
Neuronal Fc gamma receptor I as a novel mediator for IgG immune complex-induced peripheral sensitization.
Lintao Qu.
Neural Regen Res, 2012 Sep 15; 7(26). PMID: 25624839    Free PMC article.
Review.
The presence of FCGR2B promoter or transmembrane region variant alleles leads to reduced serum IL-6 levels in rheumatoid arthritis.
Stefanie Meister, Robby Engelmann, Christian Kneitz, Brigitte Müller-Hilke.
Rheumatol Int, 2015 Jan 30; 35(8). PMID: 25630523
Macrophages are critical effectors of antibody therapies for cancer.
Kipp Weiskopf, Irving L Weissman.
MAbs, 2015 Feb 11; 7(2). PMID: 25667985    Free PMC article.
Highly Cited. Review.
Antibody effector functions mediated by Fcγ-receptors are compromised during persistent viral infection.
Andreas Wieland, Rangaiah Shashidharamurthy, +9 authors, Rafi Ahmed.
Immunity, 2015 Feb 15; 42(2). PMID: 25680276    Free PMC article.
Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection.
Douglas H Yamada, Heidi Elsaesser, +5 authors, David G Brooks.
Immunity, 2015 Feb 15; 42(2). PMID: 25680277    Free PMC article.
B cells and antibodies in the defense against Mycobacterium tuberculosis infection.
Jacqueline M Achkar, John Chan, Arturo Casadevall.
Immunol Rev, 2015 Feb 24; 264(1). PMID: 25703559    Free PMC article.
Highly Cited. Review.
Neutralization of (NK-cell-derived) B-cell activating factor by Belimumab restores sensitivity of chronic lymphoid leukemia cells to direct and Rituximab-induced NK lysis.
J Wild, B J Schmiedel, +6 authors, H R Salih.
Leukemia, 2015 Feb 25; 29(8). PMID: 25710310
Clinical characteristics of male and female Korean patients with systemic lupus erythematosus: a comparative study.
Jiwon Hwang, Jaejoon Lee, +3 authors, Eun-Mi Koh.
Korean J Intern Med, 2015 Mar 10; 30(2). PMID: 25750567    Free PMC article.
Control of cytokine production by human fc gamma receptors: implications for pathogen defense and autoimmunity.
Lisa T C Vogelpoel, Dominique L P Baeten, Esther C de Jong, Jeroen den Dunnen.
Front Immunol, 2015 Mar 12; 6. PMID: 25759693    Free PMC article.
Review.
Metabolic control of B cells: more questions than answers.
Melania Capasso, Alaa Rashed Alyahyawi, Sarah Spear.
Front Immunol, 2015 Mar 13; 6. PMID: 25762999    Free PMC article.
Review.
The long pentraxin PTX3 promotes fibrocyte differentiation.
Darrell Pilling, Nehemiah Cox, +2 authors, Richard H Gomer.
PLoS One, 2015 Mar 17; 10(3). PMID: 25774777    Free PMC article.
Reduced Atherosclerosis in apoE-inhibitory FcγRIIb-Deficient Mice Is Associated With Increased Anti-Inflammatory Responses by T Cells and Macrophages.
Hang Pong Ng, Xinmei Zhu, +2 authors, Shanmugam Nagarajan.
Arterioscler Thromb Vasc Biol, 2015 Mar 21; 35(5). PMID: 25792447    Free PMC article.
Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells.
Yawu Jing, Zhenya Ni, +4 authors, Bruce Walcheck.
PLoS One, 2015 Mar 31; 10(3). PMID: 25816339    Free PMC article.
Immune complexes regulate bone metabolism through FcRγ signalling.
Takako Negishi-Koga, Hans-Jürgen Gober, +8 authors, Hiroshi Takayanagi.
Nat Commun, 2015 Apr 01; 6. PMID: 25824719
Siglec receptors impact mammalian lifespan by modulating oxidative stress.
Flavio Schwarz, Oliver M T Pearce, +14 authors, Pascal Gagneux.
Elife, 2015 Apr 08; 4. PMID: 25846707    Free PMC article.
Variation at FCGR2A and functionally related genes is associated with the response to anti-TNF therapy in rheumatoid arthritis.
Gabriela Avila-Pedretti, Jesús Tornero, +14 authors, Sara Marsal.
PLoS One, 2015 Apr 08; 10(4). PMID: 25848939    Free PMC article.
A Bivalent, Chimeric Rabies Virus Expressing Simian Immunodeficiency Virus Envelope Induces Multifunctional Antibody Responses.
Amber Dunkel, Shixue Shen, +2 authors, James P McGettigan.
AIDS Res Hum Retroviruses, 2015 Apr 08; 31(11). PMID: 25848984    Free PMC article.
Inflammatory bowel disease associates with proinflammatory potential of the immunoglobulin G glycome.
Irena Trbojević Akmačić, Nicholas T Ventham, +16 authors, IBD-BIOM Consortium.
Inflamm Bowel Dis, 2015 Apr 22; 21(6). PMID: 25895110    Free PMC article.
Highly Cited.
Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils.
K Thomsen, L Christophersen, +3 authors, N Høiby.
Infect Immun, 2015 Apr 22; 83(7). PMID: 25895968    Free PMC article.
C-reactive protein directly suppresses Th1 cell differentiation and alleviates experimental autoimmune encephalomyelitis.
Lin Zhang, Shan-Hui Liu, +7 authors, Yi Wu.
J Immunol, 2015 Apr 29; 194(11). PMID: 25917100    Free PMC article.
Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients.
Emanuela Romano, Monika Kusio-Kobialka, +7 authors, Daniel E Speiser.
Proc Natl Acad Sci U S A, 2015 Apr 29; 112(19). PMID: 25918390    Free PMC article.
Highly Cited.
Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI.
Masato Kiyoshi, Jose M M Caaveiro, +5 authors, Kouhei Tsumoto.
Nat Commun, 2015 May 01; 6. PMID: 25925696    Free PMC article.
Anti-Ganglioside Antibodies Induce Nodal and Axonal Injury via Fcγ Receptor-Mediated Inflammation.
Lan He, Gang Zhang, +2 authors, Kazim A Sheikh.
J Neurosci, 2015 May 01; 35(17). PMID: 25926454    Free PMC article.
An Fc engineering approach that modulates antibody-dependent cytokine release without altering cell-killing functions.
Michelle Kinder, Allison R Greenplate, +2 authors, Randall J Brezski.
MAbs, 2015 May 02; 7(3). PMID: 25933349    Free PMC article.
FcRn: The Architect Behind the Immune and Nonimmune Functions of IgG and Albumin.
Michal Pyzik, Timo Rath, +2 authors, Richard S Blumberg.
J Immunol, 2015 May 03; 194(10). PMID: 25934922    Free PMC article.
Highly Cited. Review.
Intranasal and oral vaccination with protein-based antigens: advantages, challenges and formulation strategies.
Shujing Wang, Huiqin Liu, Xinyi Zhang, Feng Qian.
Protein Cell, 2015 May 07; 6(7). PMID: 25944045    Free PMC article.
Review.
Potent anti-tumor response by targeting B cell maturation antigen (BCMA) in a mouse model of multiple myeloma.
Felix Oden, Stephen F Marino, +11 authors, Martin Lipp.
Mol Oncol, 2015 May 09; 9(7). PMID: 25953704    Free PMC article.
Downmodulation of vaccine-induced immunity and protection against the intracellular bacterium Francisella tularensis by the inhibitory receptor FcγRIIB.
Brian J Franz, Ying Li, +5 authors, Edmund J Gosselin.
J Immunol Res, 2015 May 12; 2015. PMID: 25961064    Free PMC article.
Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium.
Edward Chaum, Christina S Winborn, Sujoy Bhattacharya.
Mamm Genome, 2015 May 13; 26(5-6). PMID: 25963977    Free PMC article.
Is infant immunization by breastfeeding possible?
Valerie Verhasselt.
Philos Trans R Soc Lond B Biol Sci, 2015 May 13; 370(1671). PMID: 25964452    Free PMC article.
Review.
Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect.
David J DiLillo, Jeffrey V Ravetch.
Cell, 2015 May 16; 161(5). PMID: 25976835    Free PMC article.
Highly Cited.
Related Mechanisms of Antibody Somatic Hypermutation and Class Switch Recombination.
Joyce K Hwang, Frederick W Alt, Leng-Siew Yeap.
Microbiol Spectr, 2015 Jun 25; 3(1). PMID: 26104555    Free PMC article.
Review.
DC-SIGN activation mediates the differential effects of SAP and CRP on the innate immune system and inhibits fibrosis in mice.
Nehemiah Cox, Darrell Pilling, Richard H Gomer.
Proc Natl Acad Sci U S A, 2015 Jun 25; 112(27). PMID: 26106150    Free PMC article.
Distinct and synergistic roles of FcγRIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and autoimmunity.
Chetna Soni, Phillip P Domeier, +7 authors, Ziaur S M Rahman.
J Autoimmun, 2015 Jul 15; 63. PMID: 26162758    Free PMC article.
Serum protein gamma-glutamyl hydrolase, Ig gamma-3 chain C region, and haptoglobin are associated with the syndromes of pulmonary tuberculosis in traditional Chinese medicine.
Ting-Ting Jiang, Chong Wang, +6 authors, Ji-Cheng Li.
BMC Complement Altern Med, 2015 Jul 23; 15. PMID: 26198726    Free PMC article.
Glycoengineered Monoclonal Antibodies with Homogeneous Glycan (M3, G0, G2, and A2) Using a Chemoenzymatic Approach Have Different Affinities for FcγRIIIa and Variable Antibody-Dependent Cellular Cytotoxicity Activities.
Masaki Kurogochi, Masako Mori, +12 authors, Takashi Shirai.
PLoS One, 2015 Jul 23; 10(7). PMID: 26200113    Free PMC article.
Association of systemic lupus erythematosus with decreased immunosuppressive potential of the IgG glycome.
Frano Vučković, Jasminka Krištić, +25 authors, Gordan Lauc.
Arthritis Rheumatol, 2015 Jul 23; 67(11). PMID: 26200652    Free PMC article.
Highly Cited.
The Structural Role of Antibody N-Glycosylation in Receptor Interactions.
Ganesh P Subedi, Adam W Barb.
Structure, 2015 Jul 28; 23(9). PMID: 26211613    Free PMC article.
Highly Cited.
Insights into the effector functions of human IgG3 in the context of an antibody targeting transferrin receptor 1.
Lai Sum Leoh, Tracy R Daniels-Wells, Otoniel Martínez-Maza, Manuel L Penichet.
Mol Immunol, 2015 Aug 02; 67(2 Pt B). PMID: 26232328    Free PMC article.
Short Communication: Exploring Antibody Potential as Prophylactic/Therapeutic Strategies for Prevention of Early Mucosal HIV-1 Infection.
Bin Su, Maryse Peressin, +6 authors, Christiane Moog.
AIDS Res Hum Retroviruses, 2015 Aug 08; 31(11). PMID: 26252799    Free PMC article.
Characterization of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori).
Minoru Tada, Ken-ichiro Tatematsu, +5 authors, Nana Kawasaki.
MAbs, 2015 Aug 12; 7(6). PMID: 26261057    Free PMC article.
Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.
Helena Ågerstam, Christine Karlsson, +13 authors, Thoas Fioretos.
Proc Natl Acad Sci U S A, 2015 Aug 12; 112(34). PMID: 26261316    Free PMC article.
Mucosal B Cells Are Associated with Delayed SIV Acquisition in Vaccinated Female but Not Male Rhesus Macaques Following SIVmac251 Rectal Challenge.
Iskra Tuero, Venkatramanan Mohanram, +15 authors, Marjorie Robert-Guroff.
PLoS Pathog, 2015 Aug 13; 11(8). PMID: 26267144    Free PMC article.
The role of Fc-FcγR interactions in IgG-mediated microbial neutralization.
Stylianos Bournazos, David J DiLillo, Jeffrey V Ravetch.
J Exp Med, 2015 Aug 19; 212(9). PMID: 26282878    Free PMC article.
Highly Cited. Review.
Isotype Diversification of IgG Antibodies to HIV Gag Proteins as a Therapeutic Vaccination Strategy for HIV Infection.
Martyn A French, Laila N Abudulai, Sonia Fernandez.
Vaccines (Basel), 2013 Jan 01; 1(3). PMID: 26344116    Free PMC article.
Review.
Dissecting the Role of Anti-ganglioside Antibodies in Guillain-Barré Syndrome: an Animal Model Approach.
Pallavi Asthana, Joaquim Si Long Vong, +4 authors, Chi Him Eddie Ma.
Mol Neurobiol, 2015 Sep 17; 53(7). PMID: 26374552
Review.
Deregulated Fcγ receptor expression in patients with CIDP.
Isaak Quast, Flavio Cueni, +2 authors, Jan D Lünemann.
Neurol Neuroimmunol Neuroinflamm, 2015 Sep 18; 2(5). PMID: 26380354    Free PMC article.
Elevated Membrane and Soluble CD64: A Novel Marker Reflecting Altered FcγR Function and Disease in Early Rheumatoid Arthritis That Can Be Regulated by Anti-Rheumatic Treatment.
Peter Matt, Ulla Lindqvist, Sandra Kleinau.
PLoS One, 2015 Sep 26; 10(9). PMID: 26406605    Free PMC article.
Association between FCGR3B copy number variations and susceptibility to autoimmune diseases: a meta-analysis.
Young Ho Lee, Sang-Cheol Bae, +4 authors, Gwan Gyu Song.
Inflamm Res, 2015 Sep 27; 64(12). PMID: 26407570
Review.
Cooperative and alternate functions for STIM1 and STIM2 in macrophage activation and in the context of inflammation.
Georgios Sogkas, David Stegner, +6 authors, Johannes Engelbert Gessner.
Immun Inflamm Dis, 2015 Sep 30; 3(3). PMID: 26417434    Free PMC article.
Testing the role of the FcγRIIB immunoreceptor tyrosine-based inhibitory motif in regulation of the B cell immune response.
Raja Vuyyuru, Shixue Shen, Tim Manser.
Immun Inflamm Dis, 2015 Sep 30; 3(3). PMID: 26417440    Free PMC article.
Comparing the efficacy and neuroinflammatory potential of three anti-abeta antibodies.
James P Fuller, Jeffrey B Stavenhagen, +3 authors, Jessica L Teeling.
Acta Neuropathol, 2015 Oct 05; 130(5). PMID: 26433971    Free PMC article.
Importance of the Side Chain at Position 296 of Antibody Fc in Interactions with FcγRIIIa and Other Fcγ Receptors.
Yuya Isoda, Hirokazu Yagi, +5 authors, Shigeru Iida.
PLoS One, 2015 Oct 09; 10(10). PMID: 26444434    Free PMC article.
Tumor-binding antibodies and tumor immunity.
Yaron Carmi, Edgar G Engleman.
Oncotarget, 2015 Oct 13; 6(34). PMID: 26457878    Free PMC article.
Fc receptors and their influence on efficacy of therapeutic antibodies for treatment of viral diseases.
Kuan Rong Chan, Eugenia Z Ong, Darren Z L Mok, Eng Eong Ooi.
Expert Rev Anti Infect Ther, 2015 Oct 16; 13(11). PMID: 26466016    Free PMC article.
Review.
Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses.
Frederick W Holtsberg, Sergey Shulenin, +20 authors, M Javad Aman.
J Virol, 2015 Oct 16; 90(1). PMID: 26468533    Free PMC article.
Highly Cited.
Protective Role of Rho Guanosine Diphosphate Dissociation Inhibitor, Ly-GDI, in Pulmonary Alveolitis.
Chunguang Yan, Ximo Wang, +3 authors, Hongwei Gao.
PLoS One, 2015 Oct 16; 10(10). PMID: 26469087    Free PMC article.
Systemic Sclerosis Patients Present Alterations in the Expression of Molecules Involved in B-Cell Regulation.
Lilian Soto, Ashley Ferrier, +7 authors, Diego Catalán.
Front Immunol, 2015 Oct 21; 6. PMID: 26483788    Free PMC article.
A bone to pick with Fc gamma receptors.
Christian M Karsten, Jörg Köhl.
Ann Transl Med, 2015 Oct 22; 3(15). PMID: 26488014    Free PMC article.
Association study of copy number variants in FCGR3A and FCGR3B gene with risk of ankylosing spondylitis in a Chinese population.
Li Wang, Xiao Yang, +11 authors, Faming Pan.
Rheumatol Int, 2015 Oct 24; 36(3). PMID: 26494566
Human IgG4: a structural perspective.
Anna M Davies, Brian J Sutton.
Immunol Rev, 2015 Oct 27; 268(1). PMID: 26497518    Free PMC article.
Review.
TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity.
Stian Foss, Ruth Watkinson, +2 authors, Jan Terje Andersen.
Immunol Rev, 2015 Oct 27; 268(1). PMID: 26497531    Free PMC article.
Review.
Structural insights into the interaction of human IgG1 with FcγRI: no direct role of glycans in binding.
Vaheh Oganesyan, Yariv Mazor, +8 authors, William F Dall'Acqua.
Acta Crystallogr D Biol Crystallogr, 2015 Nov 04; 71(Pt 11). PMID: 26527150    Free PMC article.
Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells.
Derek D Sloan, Chia-Ying Kao Lam, +11 authors, Scott Koenig.
PLoS Pathog, 2015 Nov 06; 11(11). PMID: 26539983    Free PMC article.
Mechanisms of antibody-mediated acute and chronic rejection of kidney allografts.
William M Baldwin, Anna Valujskikh, Robert L Fairchild.
Curr Opin Organ Transplant, 2015 Nov 18; 21(1). PMID: 26575854    Free PMC article.
Review.
DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients.
Isabella C Hirako, Carolina Gallego-Marin, +10 authors, Ricardo T Gazzinelli.
mBio, 2015 Nov 19; 6(6). PMID: 26578679    Free PMC article.
Synthesis of a Liposomal MUC1 Glycopeptide-Based Immunotherapeutic and Evaluation of the Effect of l-Rhamnose Targeting on Cellular Immune Responses.
Partha Karmakar, Kyunghee Lee, +2 authors, Steven J Sucheck.
Bioconjug Chem, 2015 Nov 26; 27(1). PMID: 26595674    Free PMC article.
Generation of new peptide-Fc fusion proteins that mediate antibody-dependent cellular cytotoxicity against different types of cancer cells.
Mouldy Sioud, Phuong Westby, Julie Kristine E Olsen, Anne Mobergslien.
Mol Ther Methods Clin Dev, 2015 Nov 26; 2. PMID: 26605373    Free PMC article.
Neutralizing Antibody Response and Antibody-Dependent Cellular Cytotoxicity in HIV-1-Infected Individuals from Guinea-Bissau and Denmark.
Marie Borggren, Sanne Skov Jensen, +8 authors, Anders Fomsgaard.
AIDS Res Hum Retroviruses, 2015 Dec 02; 32(5). PMID: 26621287    Free PMC article.
Recent Advances in Kawasaki Disease.
Kyu Yeun Kim, Dong Soo Kim.
Yonsei Med J, 2015 Dec 04; 57(1). PMID: 26632378    Free PMC article.
Review.
Antimicrobial Mechanisms of Macrophages and the Immune Evasion Strategies of Staphylococcus aureus.
Ronald S Flannagan, Bryan Heit, David E Heinrichs.
Pathogens, 2015 Dec 04; 4(4). PMID: 26633519    Free PMC article.
Review.
Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells.
Stephanie Vogel, Elena Grabski, +12 authors, Ulrich Kalinke.
Sci Rep, 2015 Dec 17; 5. PMID: 26670584    Free PMC article.
SLE-associated risk factors affect DC function.
Myoungsun Son, Sun Jung Kim, Betty Diamond.
Immunol Rev, 2015 Dec 20; 269(1). PMID: 26683148    Free PMC article.
Review.
A human monoclonal antibody against small envelope protein of hepatitis B virus with potent neutralization effect.
Wei Wang, Lina Sun, +11 authors, Shuping Tong.
MAbs, 2015 Dec 30; 8(3). PMID: 26713590    Free PMC article.
B cells with regulatory properties in transplantation tolerance.
Justine Durand, Elise Chiffoleau.
World J Transplant, 2016 Jan 02; 5(4). PMID: 26722647    Free PMC article.
Review.
IgG4 Characteristics and Functions in Cancer Immunity.
Silvia Crescioli, Isabel Correa, +4 authors, Sophia N Karagiannis.
Curr Allergy Asthma Rep, 2016 Jan 09; 16(1). PMID: 26742760    Free PMC article.
Review.
Validation of research trajectory 1 of an Exposome framework: Exposure to benzo(a)pyrene confers enhanced susceptibility to bacterial infection.
Ryan S Clark, Samuel T Pellom, +9 authors, Darryl B Hood.
Environ Res, 2016 Jan 15; 146. PMID: 26765097    Free PMC article.
Recombinant factor VIII Fc (rFVIIIFc) fusion protein reduces immunogenicity and induces tolerance in hemophilia A mice.
Sriram Krishnamoorthy, Tongyao Liu, +8 authors, Haiyan Jiang.
Cell Immunol, 2016 Jan 18; 301. PMID: 26775174    Free PMC article.
IgG Glycome in Colorectal Cancer.
Frano Vučković, Evropi Theodoratou, +14 authors, Gordan Lauc.
Clin Cancer Res, 2016 Feb 03; 22(12). PMID: 26831718    Free PMC article.
Identification of novel plasma glycosylation-associated markers of aging.
Mariangela Catera, Vincenzo Borelli, +10 authors, Fabio Dall'Olio.
Oncotarget, 2016 Feb 04; 7(7). PMID: 26840264    Free PMC article.
Enhancing the safety of antibody-based immunomodulatory cancer therapy without compromising therapeutic benefit: Can we have our cake and eat it too?
Joseph M Ryan, Jeffrey S Wasser, Adam J Adler, Anthony T Vella.
Expert Opin Biol Ther, 2016 Feb 09; 16(5). PMID: 26855028    Free PMC article.
Review.
Engineered IgG1-Fc--one fragment to bind them all.
Elisabeth Lobner, Michael W Traxlmayr, Christian Obinger, Christoph Hasenhindl.
Immunol Rev, 2016 Feb 13; 270(1). PMID: 26864108    Free PMC article.
Review.
A hematopoietic cell-driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education.
Ning Wu, Ming-Chao Zhong, +7 authors, André Veillette.
Nat Immunol, 2016 Feb 16; 17(4). PMID: 26878112
Prognostic relevance of HER2/neu in acute lymphoblastic leukemia and induction of NK cell reactivity against primary ALL blasts by trastuzumab.
Sebastian P Haen, Benjamin J Schmiedel, +7 authors, Helmut R Salih.
Oncotarget, 2016 Feb 18; 7(11). PMID: 26887048    Free PMC article.
Potential Mechanisms for IgG4 Inhibition of Immediate Hypersensitivity Reactions.
Louisa K James, Stephen J Till.
Curr Allergy Asthma Rep, 2016 Feb 20; 16(3). PMID: 26892721    Free PMC article.
Review.
Functional Role of FcγRIIB in the Regulation of Mesenchymal Stem Cell Function.
Tianyi Zhu, Ruohua Chen, +7 authors, Chong Bai.
Int J Med Sci, 2016 Mar 05; 13(2). PMID: 26941575    Free PMC article.
Glutamate dependent NMDA receptor 2D is a novel angiogenic tumour endothelial marker in colorectal cancer.
Henry J M Ferguson, Joseph W Wragg, +3 authors, Roy Bicknell.
Oncotarget, 2016 Mar 05; 7(15). PMID: 26943033    Free PMC article.
TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity.
Stian Foss, Ruth E Watkinson, +8 authors, Jan Terje Andersen.
J Immunol, 2016 Mar 11; 196(8). PMID: 26962230    Free PMC article.
Involvement of B cells in non-infectious uveitis.
Justine R Smith, Andrew J Stempel, Arpita Bharadwaj, Binoy Appukuttan.
Clin Transl Immunology, 2016 Mar 11; 5(2). PMID: 26962453    Free PMC article.
Review.
Molecular modeling of antibodies for the treatment of TNFα-related immunological diseases.
Ciro Leonardo Pierri, Fabrizio Bossis, +4 authors, Domenico Tricarico.
Pharmacol Res Perspect, 2016 Mar 16; 4(1). PMID: 26977294    Free PMC article.
Computationally Designed Bispecific Antibodies using Negative State Repertoires.
Andrew Leaver-Fay, Karen J Froning, +10 authors, Brian Kuhlman.
Structure, 2016 Mar 22; 24(4). PMID: 26996964    Free PMC article.
Rapid and Long-Term Immunity Elicited by DNA-Encoded Antibody Prophylaxis and DNA Vaccination Against Chikungunya Virus.
Karuppiah Muthumani, Peter Block, +15 authors, David B Weiner.
J Infect Dis, 2016 Mar 24; 214(3). PMID: 27001960    Free PMC article.
Highly Cited.
New Insights into Molecular Mechanisms of Immune Complex-Induced Injury in Lung.
Peter A Ward, Fatemeh Fattahi, Markus Bosmann.
Front Immunol, 2016 Mar 26; 7. PMID: 27014266    Free PMC article.
Review.
DC-STAMP: A Key Regulator in Osteoclast Differentiation.
Ya-Hui Chiu, Christopher T Ritchlin.
J Cell Physiol, 2016 Mar 29; 231(11). PMID: 27018136    Free PMC article.
Review.
Signals and Receptors.
Carl-Henrik Heldin, Benson Lu, Ron Evans, J Silvio Gutkind.
Cold Spring Harb Perspect Biol, 2016 Apr 03; 8(4). PMID: 27037414    Free PMC article.
Review.
The FcγR/IgG Interaction as Target for the Treatment of Autoimmune Diseases.
Peter Sondermann.
J Clin Immunol, 2016 Apr 04; 36 Suppl 1. PMID: 27039179
Review.
FCGR3A-V158F polymorphism is a disease-specific pharmacogenetic marker for the treatment of psoriasis with Fc-containing TNFα inhibitors.
E Mendrinou, A Patsatsi, +9 authors, Y Vasilopoulos.
Pharmacogenomics J, 2016 Apr 06; 17(3). PMID: 27044681
Resistance is futile: Targeting the inhibitory FcγRIIB (CD32B) to maximize immunotherapy.
Ali Roghanian, Mark S Cragg, Björn Frendéus.
Oncoimmunology, 2016 Apr 09; 5(2). PMID: 27057434    Free PMC article.
FCGR3A and FCGR3B copy number variations are risk factors for sarcoidosis.
Jianming Wu, Yunfang Li, +3 authors, Maneesh Bhargava.
Hum Genet, 2016 Apr 10; 135(7). PMID: 27059607
Associations between PTPRC rs10919563 A/G and FCGR2A R131H polymorphisms and responsiveness to TNF blockers in rheumatoid arthritis: a meta-analysis.
Young Ho Lee, Sang-Cheol Bae.
Rheumatol Int, 2016 Apr 15; 36(6). PMID: 27074847
Review.
Effect of CD16a, the surface receptor of Kupffer cells, on the growth of hepatocellular carcinoma cells.
Xiu-Yun Li, Lun Wu, +5 authors, Xiong Ding.
Int J Mol Med, 2016 Apr 16; 37(6). PMID: 27082928    Free PMC article.
Immune Complex-Induced, Nitric Oxide-Mediated Vascular Endothelial Cell Death by Phagocytes Is Prevented with Decoy FcγReceptors.
Ramanjaneya V R Mula, Deepa Machiah, +5 authors, Rangaiah Shashidharamurthy.
PLoS One, 2016 Apr 23; 11(4). PMID: 27101012    Free PMC article.
Comparison of Antibody-Dependent Cell-Mediated Cytotoxicity and Virus Neutralization by HIV-1 Env-Specific Monoclonal Antibodies.
Benjamin von Bredow, Juan F Arias, +6 authors, David T Evans.
J Virol, 2016 Apr 29; 90(13). PMID: 27122574    Free PMC article.
Highly Cited.
Expression Profile of Human Fc Receptors in Mucosal Tissue: Implications for Antibody-Dependent Cellular Effector Functions Targeting HIV-1 Transmission.
Hannah M Cheeseman, Ann M Carias, +5 authors, Robin J Shattock.
PLoS One, 2016 May 11; 11(5). PMID: 27164006    Free PMC article.
Generation of BiKEs and TriKEs to Improve NK Cell-Mediated Targeting of Tumor Cells.
Martin Felices, Todd R Lenvik, +2 authors, Daniel A Vallera.
Methods Mol Biol, 2016 May 15; 1441. PMID: 27177679    Free PMC article.
Antitumor Efficacy of Anti-GD2 IgG1 Is Enhanced by Fc Glyco-Engineering.
Hong Xu, Hongfen Guo, Irene Y Cheung, Nai-Kong V Cheung.
Cancer Immunol Res, 2016 May 20; 4(7). PMID: 27197064    Free PMC article.
Sialylated intravenous immunoglobulin suppress anti-ganglioside antibody mediated nerve injury.
Gang Zhang, Cynthia A Massaad, +4 authors, Kazim A Sheikh.
Exp Neurol, 2016 May 22; 282. PMID: 27208700    Free PMC article.
Characterization of NF-κB Reporter U937 Cells and Their Application for the Detection of Inflammatory Immune-Complexes.
Csilla Kecse-Nagy, Zoltán Szittner, +6 authors, József Prechl.
PLoS One, 2016 May 28; 11(5). PMID: 27232500    Free PMC article.
Aspergillus Cell Wall Chitin Induces Anti- and Proinflammatory Cytokines in Human PBMCs via the Fc-γ Receptor/Syk/PI3K Pathway.
K L Becker, V Aimanianda, +8 authors, F L van de Veerdonk.
mBio, 2016 Jun 02; 7(3). PMID: 27247234    Free PMC article.
Therapeutic implications of autoantibodies in rheumatoid arthritis.
Daniel Aletaha, Stephan Blüml.
RMD Open, 2016 Jun 03; 2(1). PMID: 27252890    Free PMC article.
Review.
Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement.
Rony Dahan, Bryan C Barnhart, +3 authors, Jeffrey V Ravetch.
Cancer Cell, 2016 Jun 07; 29(6). PMID: 27265505    Free PMC article.
Highly Cited.
Association of FCGR2A rs1801274 polymorphism with susceptibility to autoimmune diseases: A meta-analysis.
Chang'e Zhang, Wenju Wang, +2 authors, Shuping Guo.
Oncotarget, 2016 Oct 26; 7(26). PMID: 27270653    Free PMC article.
Perinatal HIV-1 transmission: Fc gamma receptor variability associates with maternal infectiousness and infant susceptibility.
Ria Lassaunière, Alfred Musekiwa, +2 authors, Caroline T Tiemessen.
Retrovirology, 2016 Jun 12; 13(1). PMID: 27287460    Free PMC article.
Human CD4(+) T-Cells: A Role for Low-Affinity Fc Receptors.
Anil K Chauhan.
Front Immunol, 2016 Jun 18; 7. PMID: 27313579    Free PMC article.
Review.
CD16 and CD32 Gene Polymorphisms May Contribute to Risk of Idiopathic Thrombocytopenic Purpura.
Jiannan Xu, Liyun Zhao, +2 authors, Hui Chen.
Med Sci Monit, 2016 Jun 19; 22. PMID: 27315784    Free PMC article.
Review.
Enhancement of Immune Effector Functions by Modulating IgG's Intrinsic Affinity for Target Antigen.
Yariv Mazor, Chunning Yang, +4 authors, William F Dall'Acqua.
PLoS One, 2016 Jun 21; 11(6). PMID: 27322177    Free PMC article.
FcγR mediates TLR2- and Syk-dependent NLRP3 inflammasome activation by inactivated Francisella tularensis LVS immune complexes.
Ellen B Duffy, Sivakumar Periasamy, +2 authors, Jonathan A Harton.
J Leukoc Biol, 2016 Jul 02; 100(6). PMID: 27365531    Free PMC article.
Third-stage Gnathostoma spinigerum larva excretory secretory antigens modulate function of Fc gamma receptor I-mediated monocytes in peripheral blood mononuclear cell culture.
Surachet Benjathummarak, Ratchanok Kumsiri, +4 authors, Yaowapa Maneerat.
Trop Med Health, 2016 Jul 12; 44. PMID: 27398064    Free PMC article.
An Fc-optimized CD133 antibody for induction of NK cell reactivity against myeloid leukemia.
S P Koerner, M C André, +8 authors, H R Salih.
Leukemia, 2016 Jul 21; 31(2). PMID: 27435001
Modulation of Stat-1 in Human Macrophages Infected with Different Species of Intracellular Pathogenic Bacteria.
Giuditta Fiorella Schiavano, Sabrina Dominici, +3 authors, Mauro Magnani.
J Immunol Res, 2016 Jul 21; 2016. PMID: 27437406    Free PMC article.
Enhancement of antibody-dependent cell mediated cytotoxicity: a new era in cancer treatment.
Narendiran Rajasekaran, Cariad Chester, +2 authors, Holbrook E Kohrt.
Immunotargets Ther, 2015 Jan 01; 4. PMID: 27471715    Free PMC article.
Review.
Immune Monitoring of Trans-endothelial Transport by Kidney-Resident Macrophages.
Efstathios G Stamatiades, Marie-Eve Tremblay, +11 authors, Frederic Geissmann.
Cell, 2016 Aug 02; 166(4). PMID: 27477514    Free PMC article.
Highly Cited.
Characterization of low affinity Fcγ receptor biotinylation under controlled reaction conditions by mass spectrometry and ligand binding analysis.
Karin P M Geuijen, David F Egging, +3 authors, Michel H Eppink.
Protein Sci, 2016 Aug 02; 25(10). PMID: 27479529    Free PMC article.
Broadly Neutralizing Activity of Zika Virus-Immune Sera Identifies a Single Viral Serotype.
Kimberly A Dowd, Christina R DeMaso, +10 authors, Theodore C Pierson.
Cell Rep, 2016 Aug 03; 16(6). PMID: 27481466    Free PMC article.
Highly Cited.
Converting monoclonal antibody-based immunotherapies from passive to active: bringing immune complexes into play.
Jennifer Lambour, Mar Naranjo-Gomez, Marc Piechaczyk, Mireia Pelegrin.
Emerg Microbes Infect, 2016 Aug 18; 5(8). PMID: 27530750    Free PMC article.
Review.
Malignant Mesothelioma Effusions Are Infiltrated by CD3+ T Cells Highly Expressing PD-L1 and the PD-L1+ Tumor Cells within These Effusions Are Susceptible to ADCC by the Anti-PD-L1 Antibody Avelumab.
Swati Khanna, Anish Thomas, +8 authors, Raffit Hassan.
J Thorac Oncol, 2016 Oct 25; 11(11). PMID: 27544053    Free PMC article.
Immunoregulatory functions of immune complexes in vaccine and therapy.
Yu-Mei Wen, Libing Mu, Yan Shi.
EMBO Mol Med, 2016 Aug 31; 8(10). PMID: 27572622    Free PMC article.
Review.
Investigation of the Immunomodulatory effect of Berberis vulgaris on core-pulsed dendritic cell vaccine.
Doaa A Ghareeb, Eiman H Elwakeel, +2 authors, Maha A El Demellawy.
BMC Complement Altern Med, 2016 Sep 01; 16(1). PMID: 27577059    Free PMC article.
Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses.
Matthew Zirui Tay, Pinghuang Liu, +12 authors, Georgia D Tomaras.
PLoS Pathog, 2016 Sep 01; 12(8). PMID: 27579713    Free PMC article.
Highly Cited.
Effects of anchor structure and glycosylation of Fcγ receptor III on ligand binding affinity.
Ning Jiang, Wei Chen, +4 authors, Cheng Zhu.
Mol Biol Cell, 2016 Nov 05; 27(22). PMID: 27582391    Free PMC article.
Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology.
Mark J Selby, John J Engelhardt, +11 authors, Alan J Korman.
PLoS One, 2016 Sep 10; 11(9). PMID: 27610613    Free PMC article.
Highly Cited.
Effects of allergic diseases and age on the composition of serum IgG glycome in children.
Marija Pezer, Jerko Stambuk, +13 authors, Gordan Lauc.
Sci Rep, 2016 Sep 13; 6. PMID: 27616597    Free PMC article.
Active but not inactive granulomatosis with polyangiitis is associated with decreased and phenotypically and functionally altered CD56(dim) natural killer cells.
Wolfgang Merkt, Maren Claus, +4 authors, Carsten Watzl.
Arthritis Res Ther, 2016 Sep 15; 18(1). PMID: 27624647    Free PMC article.
Rituximab induces phenotypical and functional changes of NK cells in a non-malignant experimental setting.
Wolfgang Merkt, Hanns-Martin Lorenz, Carsten Watzl.
Arthritis Res Ther, 2016 Sep 16; 18(1). PMID: 27629249    Free PMC article.
Regulation of FcRγ function by site-specific serine phosphorylation.
Spandan Shah, Andrew W Gibson, +5 authors, Robert P Kimberly.
J Leukoc Biol, 2016 Sep 16; 101(2). PMID: 27630214    Free PMC article.
Myeloid-derived suppressor cells in murine AIDS inhibit B-cell responses in part via soluble mediators including reactive oxygen and nitrogen species, and TGF-β.
Jessica L Rastad, William R Green.
Virology, 2016 Sep 16; 499. PMID: 27632561    Free PMC article.
A Functional Role for Antibodies in Tuberculosis.
Lenette L Lu, Amy W Chung, +22 authors, Galit Alter.
Cell, 2016 Sep 27; 167(2). PMID: 27667685    Free PMC article.
Highly Cited.
Humoral Immunity Provides Resident Intestinal Eosinophils Access to Luminal Antigen via Eosinophil-Expressed Low-Affinity Fcγ Receptors.
Kalmia M Smith, Raiann S Rahman, Lisa A Spencer.
J Immunol, 2016 Sep 30; 197(9). PMID: 27683752    Free PMC article.
Antigen modulation as a potential mechanism of anti-KEL immunoprophylaxis in mice.
Jingchun Liu, Manjula Santhanakrishnan, +7 authors, Jeanne E Hendrickson.
Blood, 2016 Oct 01; 128(26). PMID: 27688803    Free PMC article.
Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus.
Wenqian He, Gene S Tan, +8 authors, Matthew S Miller.
Proc Natl Acad Sci U S A, 2016 Oct 30; 113(42). PMID: 27698132    Free PMC article.
Highly Cited.
Impact of Glycosylation on Effector Functions of Therapeutic IgG.
Riad Abès, Jean-Luc Teillaud.
Pharmaceuticals (Basel), 2010 Jan 12; 3(1). PMID: 27713246    Free PMC article.
Review.
Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) Regulates Osteoclast Differentiation via the Ca2+ /NFATc1 Axis.
Ya-Hui Chiu, Edward Schwarz, +12 authors, Christopher T Ritchlin.
J Cell Physiol, 2016 Oct 11; 232(9). PMID: 27723141    Free PMC article.
Leukocyte immunoglobulin-like receptor B4 regulates key signalling molecules involved in FcγRI-mediated clathrin-dependent endocytosis and phagocytosis.
Mijeong Park, Mark J Raftery, +3 authors, Nicodemus Tedla.
Sci Rep, 2016 Oct 12; 6. PMID: 27725776    Free PMC article.
Soluble fibrinogen like protein 2 (sFGL2), the novel effector molecule for immunoregulation.
Xin-Guang Liu, Yu Liu, Feng Chen.
Oncotarget, 2016 Oct 13; 8(2). PMID: 27732962    Free PMC article.
Review.
FCGR Polymorphisms Influence Response to IL2 in Metastatic Renal Cell Carcinoma.
Amy K Erbe, Wei Wang, +15 authors, Paul M Sondel.
Clin Cancer Res, 2016 Nov 01; 23(9). PMID: 27742794    Free PMC article.
FcμR in human B cell subsets in primary selective IgM deficiency, and regulation of FcμR and production of natural IgM antibodies by IGIV.
Sudhir Gupta, Sudhanshu Agrawal, Sastry Gollapudi, Hiromi Kubagawa.
Hum Immunol, 2016 Oct 19; 77(12). PMID: 27751883    Free PMC article.
The contribution of the programmed cell death machinery in innate immune cells to lupus nephritis.
FuNien Tsai, Harris Perlman, Carla M Cuda.
Clin Immunol, 2016 Nov 05; 185. PMID: 27780774    Free PMC article.
Review.
Immunoglobulin Glycosylation Effects in Allergy and Immunity.
Alexandra Epp, Kathryn C Sullivan, Andrew B Herr, Richard T Strait.
Curr Allergy Asthma Rep, 2016 Nov 01; 16(11). PMID: 27796794
Review.
CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP.
Chizuru Akatsu, Kenro Shinagawa, +8 authors, Takeshi Tsubata.
J Exp Med, 2016 Nov 05; 213(12). PMID: 27810925    Free PMC article.
Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation.
Anissa S H Chan, Adria Bykowski Jonas, +13 authors, Nandita Bose.
PLoS One, 2016 Nov 05; 11(11). PMID: 27812183    Free PMC article.
Akt and SHP-1 are DC-intrinsic checkpoints for tumor immunity.
Yaron Carmi, Tyler R Prestwood, +10 authors, Edgar G Engleman.
JCI Insight, 2016 Nov 05; 1(18). PMID: 27812544    Free PMC article.
CD19-specific triplebody SPM-1 engages NK and γδ T cells for rapid and efficient lysis of malignant B-lymphoid cells.
Christian B Schiller, Todd A Braciak, +12 authors, Fuat S Oduncu.
Oncotarget, 2016 Nov 09; 7(50). PMID: 27825135    Free PMC article.
FcγRIIb-SHIP2 axis links Aβ to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model.
Tae-In Kam, Hyejin Park, +5 authors, Yong-Keun Jung.
Elife, 2016 Nov 12; 5. PMID: 27834631    Free PMC article.
Chicken IgY Fc Linked to Bordetella avium ompA and Taishan Pinus massoniana Pollen Polysaccharide Adjuvant Enhances Macrophage Function and Specific Immune Responses.
Wenwen Dong, Hao Zhang, +8 authors, Ruiliang Zhu.
Front Microbiol, 2016 Nov 17; 7. PMID: 27847501    Free PMC article.
Dendritic cell-elicited B-cell activation fosters immune privilege via IL-10 signals in hepatocellular carcinoma.
Fang-Zhu Ouyang, Rui-Qi Wu, +7 authors, Dong-Ming Kuang.
Nat Commun, 2016 Nov 18; 7. PMID: 27853178    Free PMC article.
A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells.
E J Cheadle, G Lipowska-Bhalla, +4 authors, T M Illidge.
Leukemia, 2016 Nov 29; 31(7). PMID: 27890931    Free PMC article.
Fc gamma receptors: glycobiology and therapeutic prospects.
Jerrard M Hayes, Mark R Wormald, Pauline M Rudd, Gavin P Davey.
J Inflamm Res, 2016 Nov 30; 9. PMID: 27895507    Free PMC article.
Review.
Sequence diversity of dengue virus type 2 in brain and thymus of infected interferon receptor ko mice: implications for dengue virulence.
Priya Dhole, Emi E Nakayama, +4 authors, Takeshi Kurosu.
Virol J, 2016 Dec 03; 13(1). PMID: 27903277    Free PMC article.
Structural Insights into Reovirus σ1 Interactions with Two Neutralizing Antibodies.
Melanie H Dietrich, Kristen M Ogden, +7 authors, Thilo Stehle.
J Virol, 2016 Dec 09; 91(4). PMID: 27928010    Free PMC article.
Understanding the Genomic Structure of Copy-Number Variation of the Low-Affinity Fcγ Receptor Region Allows Confirmation of the Association of FCGR3B Deletion with Rheumatoid Arthritis.
Raheleh Rahbari, Luciana W Zuccherato, +6 authors, Edward J Hollox.
Hum Mutat, 2016 Dec 21; 38(4). PMID: 27995740    Free PMC article.
TIARP attenuates autoantibody-mediated arthritis via the suppression of neutrophil migration by reducing CXCL2/CXCR2 and IL-6 expression.
Asuka Inoue, Isao Matsumoto, +9 authors, Takayuki Sumida.
Sci Rep, 2016 Dec 21; 6. PMID: 27995997    Free PMC article.
Cell-Based Screen Identifies Human Interferon-Stimulated Regulators of Listeria monocytogenes Infection.
Sofya S Perelman, Michael E Abrams, +5 authors, Neal M Alto.
PLoS Pathog, 2016 Dec 22; 12(12). PMID: 28002492    Free PMC article.
Fcγ-receptor IIa-mediated Src Signaling Pathway Is Essential for the Antibody-Dependent Enhancement of Ebola Virus Infection.
Wakako Furuyama, Andrea Marzi, +9 authors, Ayato Takada.
PLoS Pathog, 2016 Dec 31; 12(12). PMID: 28036370    Free PMC article.
The Impact of HLA Class I-Specific Killer Cell Immunoglobulin-Like Receptors on Antibody-Dependent Natural Killer Cell-Mediated Cytotoxicity and Organ Allograft Rejection.
Raja Rajalingam.
Front Immunol, 2017 Jan 10; 7. PMID: 28066408    Free PMC article.
Review.
Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice.
Megan Lo, Hok Seon Kim, +14 authors, James A Ernst.
J Biol Chem, 2017 Jan 13; 292(9). PMID: 28077575    Free PMC article.
Comparison of Multiple Methods for Determination of FCGR3A/B Genomic Copy Numbers in HapMap Asian Populations with Two Public Databases.
Yuan-Yuan Qi, Xu-Jie Zhou, +3 authors, Hong Zhang.
Front Genet, 2017 Jan 14; 7. PMID: 28083015    Free PMC article.
FcRγ-dependent immune activation initiates astrogliosis during the asymptomatic phase of Sandhoff disease model mice.
Yasuhiro Ogawa, Takafumi Sano, +11 authors, Kazuhiko Oishi.
Sci Rep, 2017 Jan 14; 7. PMID: 28084424    Free PMC article.
The Role and Function of Fcγ Receptors on Myeloid Cells.
Stylianos Bournazos, Taia T Wang, Jeffrey V Ravetch.
Microbiol Spectr, 2017 Jan 15; 4(6). PMID: 28087938    Free PMC article.
Review.
Targeted Fcγ Receptor (FcγR)-mediated Clearance by a Biparatopic Bispecific Antibody.
Srinath Kasturirangan, G Jonah Rainey, +10 authors, Changshou Gao.
J Biol Chem, 2017 Jan 20; 292(10). PMID: 28100773    Free PMC article.
Enhancement of antibody functions through Fc multiplications.
Qun Wang, Yan Chen, +11 authors, Xiaodong Xiao.
MAbs, 2017 Jan 20; 9(3). PMID: 28102754    Free PMC article.
Comparative transcriptomics of elasmobranchs and teleosts highlight important processes in adaptive immunity and regional endothermy.
Nicholas J Marra, Vincent P Richards, +4 authors, Mahmood S Shivji.
BMC Genomics, 2017 Jan 31; 18(1). PMID: 28132643    Free PMC article.
Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies.
Elie Dheilly, Valéry Moine, +12 authors, Krzysztof Masternak.
Mol Ther, 2017 Feb 06; 25(2). PMID: 28153099    Free PMC article.
Modulation of Microglial Cell Fcγ Receptor Expression Following Viral Brain Infection.
Priyanka Chauhan, Shuxian Hu, +2 authors, James R Lokensgard.
Sci Rep, 2017 Feb 07; 7. PMID: 28165503    Free PMC article.
Spontaneous germinal centers and autoimmunity.
Phillip P Domeier, Stephanie L Schell, Ziaur S M Rahman.
Autoimmunity, 2017 Feb 09; 50(1). PMID: 28166685    Free PMC article.
Review.
B cells interactions in lipid immune responses: implications in atherosclerotic disease.
Laura C Echeverri Tirado, Lina M Yassin.
Lipids Health Dis, 2017 Feb 09; 16(1). PMID: 28166809    Free PMC article.
Review.
Therapeutic antibody targeting of indoleamine-2,3-dioxygenase (IDO2) inhibits autoimmune arthritis.
Lauren M F Merlo, Samantha Grabler, +5 authors, Laura Mandik-Nayak.
Clin Immunol, 2017 Feb 23; 179. PMID: 28223071    Free PMC article.
Enhanced FCGR2A and FCGR3A signaling by HIV viremic controller IgG.
Raymond A Alvarez, Ana M Maestre, +11 authors, Benjamin K Chen.
JCI Insight, 2017 Feb 28; 2(4). PMID: 28239647    Free PMC article.
Modulating IgG effector function by Fc glycan engineering.
Tiezheng Li, David J DiLillo, +3 authors, Lai-Xi Wang.
Proc Natl Acad Sci U S A, 2017 Mar 16; 114(13). PMID: 28289219    Free PMC article.
Highly Cited.
Setting the target for pemphigus vulgaris therapy.
Christoph T Ellebrecht, Aimee S Payne.
JCI Insight, 2017 Mar 16; 2(5). PMID: 28289723    Free PMC article.
Review.
Help is on the way: Monoclonal antibody therapy for multi-drug resistant bacteria.
Rachelle Babb, Liise-Anne Pirofski.
Virulence, 2017 Mar 18; 8(7). PMID: 28306387    Free PMC article.
Antibody Functional Assays as Measures of Fc Receptor-Mediated Immunity to HIV - New Technologies and their Impact on the HIV Vaccine Field.
Bruce D Wines, Hugh Billings, +2 authors, P Mark Hogarth.
Curr HIV Res, 2017 Mar 23; 15(3). PMID: 28322167    Free PMC article.
Review.
Basal-like breast cancer: molecular profiles, clinical features and survival outcomes.
Heloisa H Milioli, Inna Tishchenko, +2 authors, Pablo Moscato.
BMC Med Genomics, 2017 Mar 30; 10(1). PMID: 28351365    Free PMC article.
FcγRIIb expression in early stage chronic lymphocytic leukemia.
Rosa Bosch, Alba Mora, +19 authors, Carol Moreno.
Leuk Lymphoma, 2017 Apr 05; 58(11). PMID: 28372509    Free PMC article.
Fcγ Receptor Heterogeneity in Leukocyte Functional Responses.
Carlos Rosales.
Front Immunol, 2017 Apr 05; 8. PMID: 28373871    Free PMC article.
Highly Cited. Review.
Two years' long-term follow up in chronic inflammatory demyelinating polyradiculoneuropathy: efficacy of intravenous immunoglobulin treatment.
Gisa Ellrichmann, Ralf Gold, +2 authors, Christiane Schneider-Gold.
Ther Adv Neurol Disord, 2017 Apr 07; 10(2). PMID: 28382108    Free PMC article.
Trehalose dimycolate interferes with FcγR-mediated phagosome maturation through Mincle, SHP-1 and FcγRIIB signalling.
Emmanuel C Patin, Anna C Geffken, +6 authors, Ulrich E Schaible.
PLoS One, 2017 Apr 07; 12(4). PMID: 28384255    Free PMC article.
DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo.
Christian H K Lehmann, Anna Baranska, +15 authors, Diana Dudziak.
J Exp Med, 2017 Apr 09; 214(5). PMID: 28389502    Free PMC article.
Genetic architecture of gene expression underlying variation in host response to porcine reproductive and respiratory syndrome virus infection.
Arun Kommadath, Hua Bao, +12 authors, Graham S Plastow.
Sci Rep, 2017 Apr 11; 7. PMID: 28393889    Free PMC article.
Macrophage Polarization Modulates FcγR- and CD13-Mediated Phagocytosis and Reactive Oxygen Species Production, Independently of Receptor Membrane Expression.
Elizabeth Mendoza-Coronel, Enrique Ortega.
Front Immunol, 2017 Apr 12; 8. PMID: 28396660    Free PMC article.
Targeting CD157 in AML using a novel, Fc-engineered antibody construct.
Christina Krupka, Felix S Lichtenegger, +14 authors, Marion Subklewe.
Oncotarget, 2017 Apr 19; 8(22). PMID: 28415689    Free PMC article.
The lack of BTK does not impair monocytes and polymorphonuclear cells functions in X-linked agammaglobulinemia under treatment with intravenous immunoglobulin replacement.
Filomena Monica Cavaliere, Alessandro Prezzo, +2 authors, Isabella Quinti.
PLoS One, 2017 Apr 20; 12(4). PMID: 28422989    Free PMC article.
Glycan Remodeling of Human Erythropoietin (EPO) Through Combined Mammalian Cell Engineering and Chemoenzymatic Transglycosylation.
Qiang Yang, Yanming An, +4 authors, Lai-Xi Wang.
ACS Chem Biol, 2017 Apr 30; 12(6). PMID: 28452462    Free PMC article.
Signature of the Sleeper Cell: A Biomarker of HIV Latency Revealed.
Satish K Pillai, Steven G Deeks.
Trends Immunol, 2017 May 18; 38(7). PMID: 28511815    Free PMC article.
Favorable Response to Long-term Nucleos(t)ide Analogue Therapy in HBeAg-positive Patients with High Serum Fucosyl-Agalactosyl IgG.
Cheng-Hsun Ho, Hung-Wen Tsai, +8 authors, Shu-Hui Chen.
Sci Rep, 2017 May 18; 7(1). PMID: 28512353    Free PMC article.
T0001, a variant of TNFR2-Fc fusion protein, exhibits improved Fc effector functions through increased binding to membrane-bound TNFα.
Yijun Shen, Gang Li, +9 authors, Yong Su.
PLoS One, 2017 May 26; 12(5). PMID: 28542350    Free PMC article.
The Use of Xanthan Gum as Vaccine Adjuvant: An Evaluation of Immunostimulatory Potential in BALB/c Mice and Cytotoxicity In Vitro.
Rodrigo Andrade Schuch, Thaís Larré Oliveira, +6 authors, Daiane Drawanz Hartwig.
Biomed Res Int, 2017 May 31; 2017. PMID: 28555192    Free PMC article.
Identification of Fc Gamma Receptor Glycoforms That Produce Differential Binding Kinetics for Rituximab.
Jerrard M Hayes, Asa Frostell, +8 authors, Pauline M Rudd.
Mol Cell Proteomics, 2017 Jun 04; 16(10). PMID: 28576848    Free PMC article.
Drug discovery and therapeutic delivery for the treatment of B and T cell tumors.
Regan Stephenson, Ankur Singh.
Adv Drug Deliv Rev, 2017 Jun 20; 114. PMID: 28625826    Free PMC article.
Review.
Selective activation of anti-CD73 mechanisms in control of primary tumors and metastases.
Dipti Vijayan, Deborah S Barkauskas, +7 authors, Mark J Smyth.
Oncoimmunology, 2017 Jun 24; 6(5). PMID: 28638737    Free PMC article.
Pharmacokinetics of Monoclonal Antibodies.
Josiah T Ryman, Bernd Meibohm.
CPT Pharmacometrics Syst Pharmacol, 2017 Jun 28; 6(9). PMID: 28653357    Free PMC article.
Highly Cited. Review.
Yeast lysates carrying the nucleoprotein from measles virus vaccine as a novel subunit vaccine platform to deliver Plasmodium circumsporozoite antigen.
Daria Jacob, Claude Ruffie, +5 authors, Monica Sala.
Malar J, 2017 Jul 01; 16(1). PMID: 28662722    Free PMC article.
A bioconjugate leveraging xenoreactive antibodies to alleviate cocaine-induced behavior.
NIcholas T Jacob, Kensaku Anraku, +5 authors, Kim D Janda.
Chem Commun (Camb), 2017 Jul 06; 53(58). PMID: 28677711    Free PMC article.
Engineering Aglycosylated IgG Variants with Wild-Type or Improved Binding Affinity to Human Fc Gamma RIIA and Fc Gamma RIIIAs.
Tiffany F Chen, Stephen L Sazinsky, +8 authors, K Dane Wittrup.
J Mol Biol, 2017 Jul 12; 429(16). PMID: 28694069    Free PMC article.
Regulation of Subunit-Specific Germinal Center B Cell Responses to the HIV-1 Envelope Glycoproteins by Antibody-Mediated Feedback.
Mattias N E Forsell, Linda Kvastad, +2 authors, Mikael C I Karlsson.
Front Immunol, 2017 Jul 18; 8. PMID: 28713371    Free PMC article.
Neurofilament light as an immune target for pathogenic antibodies.
Fabiola Puentes, Baukje J van der Star, +10 authors, Sandra Amor.
Immunology, 2017 Jul 19; 152(4). PMID: 28718500    Free PMC article.
The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells.
Hong-Sheng Dai, Nathaniel Griffin, +10 authors, Michael A Caligiuri.
Immunity, 2017 Jul 21; 47(1). PMID: 28723548    Free PMC article.
A pilot study on using rapamycin-carrying synthetic vaccine particles (SVP) in conjunction with enzyme replacement therapy to induce immune tolerance in Pompe disease.
Han-Hyuk Lim, Haiqing Yi, +3 authors, Priya S Kishnani.
Mol Genet Metab Rep, 2017 Aug 02; 13. PMID: 28761815    Free PMC article.
Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis.
Rosa Molfetta, Linda Quatrini, Angela Santoni, Rossella Paolini.
Int J Mol Sci, 2017 Aug 03; 18(8). PMID: 28767057    Free PMC article.
Review.
IgG cooperativity - Is there allostery? Implications for antibody functions and therapeutic antibody development.
Danlin Yang, Rachel Kroe-Barrett, +2 authors, Thomas M Laue.
MAbs, 2017 Aug 17; 9(8). PMID: 28812955    Free PMC article.
Review.
Therapeutic Potential of Intravenous Immunoglobulin in Acute Brain Injury.
Vivien Thom, Thiruma V Arumugam, Tim Magnus, Mathias Gelderblom.
Front Immunol, 2017 Aug 22; 8. PMID: 28824617    Free PMC article.
Review.
IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement.
A D van Dam, L van Beek, +10 authors, V van Harmelen.
Int J Obes (Lond), 2017 Aug 31; 42(2). PMID: 28852207
Therapeutic Antibodies against Intracellular Tumor Antigens.
Iva Trenevska, Demin Li, Alison H Banham.
Front Immunol, 2017 Sep 05; 8. PMID: 28868054    Free PMC article.
Review.
(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fcγ receptor signaling.
Qing Qi, Heng Li, +11 authors, Jian-Ping Zuo.
Acta Pharmacol Sin, 2017 Sep 08; 39(1). PMID: 28880016    Free PMC article.
Natural Killer (NK) Cell Education Differentially Influences HIV Antibody-Dependent NK Cell Activation and Antibody-Dependent Cellular Cytotoxicity.
Nicole F Bernard, Zahra Kiani, +3 authors, Franck P Dupuy.
Front Immunol, 2017 Sep 09; 8. PMID: 28883824    Free PMC article.
Review.
Male-specific association of the FCGR2A His167Arg polymorphism with Kawasaki disease.
Young-Chang Kwon, Jae-Jung Kim, +19 authors, Korean Kawasaki Disease Genetics Consortium.
PLoS One, 2017 Sep 09; 12(9). PMID: 28886140    Free PMC article.
Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases.
Hiroshi Nishi, Kazuhiro Furuhashi, +14 authors, Tanya N Mayadas.
J Clin Invest, 2017 Sep 12; 127(10). PMID: 28891817    Free PMC article.
Biodegradable Viral Nanoparticle/Polymer Implants Prepared via Melt-Processing.
Parker W Lee, Sourabh Shukla, +4 authors, Jonathan K Pokorski.
ACS Nano, 2017 Sep 14; 11(9). PMID: 28902491    Free PMC article.
Syk-dependent tyrosine phosphorylation of 3BP2 is required for optimal FcRγ-mediated phagocytosis and chemokine expression in U937 cells.
Kazuyasu Chihara, Yuji Kato, +3 authors, Kiyonao Sada.
Sci Rep, 2017 Sep 15; 7(1). PMID: 28904407    Free PMC article.
Differential antibody glycosylation in autoimmunity: sweet biomarker or modulator of disease activity?
Michaela Seeling, Christin Brückner, Falk Nimmerjahn.
Nat Rev Rheumatol, 2017 Sep 15; 13(10). PMID: 28905852
Review.
Correlation between cell aggregation and antibody production in IgE-producing plasma cells.
Mari Hikosaka, Akihiko Murata, Miya Yoshino, Shin-Ichi Hayashi.
Biochem Biophys Rep, 2017 Sep 29; 10. PMID: 28955750    Free PMC article.
Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields.
Kristina M Ilieva, Judit Fazekas-Singer, +16 authors, Sophia N Karagiannis.
Front Immunol, 2017 Sep 30; 8. PMID: 28959256    Free PMC article.
Rapid screening of IgG quality attributes - effects on Fc receptor binding.
Karin P M Geuijen, Cindy Oppers-Tiemissen, +4 authors, Michel H M Eppink.
FEBS Open Bio, 2017 Oct 06; 7(10). PMID: 28979843    Free PMC article.
IgG Fc engineering to modulate antibody effector functions.
Xinhua Wang, Mary Mathieu, Randall J Brezski.
Protein Cell, 2017 Oct 08; 9(1). PMID: 28986820    Free PMC article.
Highly Cited. Review.
Designer α1,6-Fucosidase Mutants Enable Direct Core Fucosylation of Intact N-Glycopeptides and N-Glycoproteins.
Chao Li, Shilei Zhu, Christopher Ma, Lai-Xi Wang.
J Am Chem Soc, 2017 Oct 11; 139(42). PMID: 28990779    Free PMC article.
Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice.
Wenqian He, Chi-Jene Chen, +13 authors, Gene S Tan.
Nat Commun, 2017 Oct 12; 8(1). PMID: 29018261    Free PMC article.
Highly Cited.
Complement-Activating Anti-HLA Antibodies in Kidney Transplantation: Allograft Gene Expression Profiling and Response to Treatment.
Carmen Lefaucheur, Denis Viglietti, +22 authors, Alexandre Loupy.
J Am Soc Nephrol, 2017 Oct 19; 29(2). PMID: 29042454    Free PMC article.
IFNγ Enhances CD64-Potentiated Phagocytosis of Treponema pallidum Opsonized with Human Syphilitic Serum by Human Macrophages.
Kelly L Hawley, Adriana R Cruz, +9 authors, Juan C Salazar.
Front Immunol, 2017 Oct 21; 8. PMID: 29051759    Free PMC article.
Beyond binding: antibody effector functions in infectious diseases.
Lenette L Lu, Todd J Suscovich, Sarah M Fortune, Galit Alter.
Nat Rev Immunol, 2017 Oct 25; 18(1). PMID: 29063907    Free PMC article.
Highly Cited. Review.
Recombinant Antibodies to Arm Cytotoxic Lymphocytes in Cancer Immunotherapy.
Joachim Koch, Michael Tesar.
Transfus Med Hemother, 2017 Oct 27; 44(5). PMID: 29070979    Free PMC article.
Review.
Enavatuzumab, a Humanized Anti-TWEAK Receptor Monoclonal Antibody, Exerts Antitumor Activity through Attracting and Activating Innate Immune Effector Cells.
Shiming Ye, Melvin I Fox, +8 authors, Patricia A Culp.
J Immunol Res, 2017 Oct 28; 2017. PMID: 29075649    Free PMC article.
Pro-inflammatory State in Monoclonal Gammopathy of Undetermined Significance and in Multiple Myeloma Is Characterized by Low Sialylation of Pathogen-Specific and Other Monoclonal Immunoglobulins.
Adrien Bosseboeuf, Sophie Allain-Maillet, +13 authors, Jean Harb.
Front Immunol, 2017 Nov 04; 8. PMID: 29098000    Free PMC article.
Autoimmunity and autoinflammation: A systems view on signaling pathway dysregulation profiles.
Arsen Arakelyan, Lilit Nersisyan, +5 authors, Hans Binder.
PLoS One, 2017 Nov 04; 12(11). PMID: 29099860    Free PMC article.
Tuberculosis State Is Associated with Expression of Toll-Like Receptor 2 in Sputum Macrophages.
Karim Lakehal, David Levine, +5 authors, Richard Pine.
mSphere, 2017 Nov 07; 2(6). PMID: 29104936    Free PMC article.
Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway.
Elisa Benedetti, Maja Pučić-Baković, +28 authors, Jan Krumsiek.
Nat Commun, 2017 Nov 15; 8(1). PMID: 29133956    Free PMC article.
IVIG activates FcγRIIB-SHIP1-PIP3 Pathway to stabilize mast cells and suppress inflammation after ICH in mice.
Gokce Yilmaz Akyol, Anatol Manaenko, +6 authors, Jiping Tang.
Sci Rep, 2017 Nov 16; 7(1). PMID: 29138419    Free PMC article.
Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection.
Lucien H Turner, Jeremy M Kinder, +5 authors, Sing Sing Way.
PLoS Pathog, 2017 Nov 18; 13(11). PMID: 29145516    Free PMC article.
Generation and characterization of cross neutralizing human monoclonal antibody against 4 serotypes of dengue virus without enhancing activity.
Subenya Injampa, Nataya Muenngern, +6 authors, Pannamthip Pitaksajjakul.
PeerJ, 2017 Nov 21; 5. PMID: 29152418    Free PMC article.
Interplay between Natural Killer Cells and Anti-HER2 Antibodies: Perspectives for Breast Cancer Immunotherapy.
Aura Muntasell, Mariona Cabo, +6 authors, Miguel López-Botet.
Front Immunol, 2017 Nov 29; 8. PMID: 29181007    Free PMC article.
Review.
From IgG Fusion Proteins to Engineered-Specific Human Regulatory T Cells: A Life of Tolerance.
David W Scott.
Front Immunol, 2017 Nov 29; 8. PMID: 29181011    Free PMC article.
Review.
Immunotherapeutic efficacy of liposome-encapsulated refined allergen vaccines against Dermatophagoides pteronyssinus allergy.
Urai Chaisri, Anchalee Tungtrongchitr, +6 authors, Nitat Sookrung.
PLoS One, 2017 Nov 29; 12(11). PMID: 29182623    Free PMC article.
Next generation antibody drugs: pursuit of the 'high-hanging fruit'.
Paul J Carter, Greg A Lazar.
Nat Rev Drug Discov, 2017 Dec 02; 17(3). PMID: 29192287
Highly Cited. Review.
Phagosomal transport depends strongly on phagosome size.
S Keller, K Berghoff, H Kress.
Sci Rep, 2017 Dec 08; 7(1). PMID: 29213131    Free PMC article.
Spoiling for a Fight: B Lymphocytes As Initiator and Effector Populations within Tertiary Lymphoid Organs in Autoimmunity and Transplantation.
Jawaher Alsughayyir, Gavin J Pettigrew, Reza Motallebzadeh.
Front Immunol, 2017 Dec 09; 8. PMID: 29218052    Free PMC article.
Review.
Increasing the Clinical Potential and Applications of Anti-HIV Antibodies.
Casey K Hua, Margaret E Ackerman.
Front Immunol, 2017 Dec 14; 8. PMID: 29234320    Free PMC article.
Review.
Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action.
James I Robinson, Euan W Baxter, +13 authors, Ann W Morgan.
Proc Natl Acad Sci U S A, 2017 Dec 17; 115(1). PMID: 29247053    Free PMC article.
The Role of Estrogen Membrane Receptor (G Protein-Coupled Estrogen Receptor 1) in Skin Inflammation Induced by Systemic Lupus Erythematosus Serum IgG.
Zhenming Cai, Changhao Xie, +8 authors, Guo-Min Deng.
Front Immunol, 2017 Dec 20; 8. PMID: 29255468    Free PMC article.
Engineered Sialylation of Pathogenic Antibodies In Vivo Attenuates Autoimmune Disease.
Jose D Pagan, Maya Kitaoka, Robert M Anthony.
Cell, 2017 Dec 26; 172(3). PMID: 29275858    Free PMC article.
Highly Cited.
The Phagocytic Function of Macrophage-Enforcing Innate Immunity and Tissue Homeostasis.
Daisuke Hirayama, Tomoya Iida, Hiroshi Nakase.
Int J Mol Sci, 2017 Dec 30; 19(1). PMID: 29286292    Free PMC article.
Highly Cited. Review.
Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex.
Marianna Stamou, Ana Cristina Grodzki, +2 authors, Pamela J Lein.
J Neuroinflammation, 2018 Jan 08; 15(1). PMID: 29306331    Free PMC article.
Development and characterization of an anti-rituximab monoclonal antibody panel.
Minoru Tada, Takuo Suzuki, Akiko Ishii-Watabe.
MAbs, 2018 Jan 09; 10(3). PMID: 29309213    Free PMC article.
Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals.
Lars Torkel Hellman, Srinivas Akula, Michael Thorpe, Zhirong Fu.
Front Immunol, 2018 Jan 10; 8. PMID: 29312297    Free PMC article.
Review.
Characterization of novel endo-β-N-acetylglucosaminidases from Sphingobacterium species, Beauveria bassiana and Cordyceps militaris that specifically hydrolyze fucose-containing oligosaccharides and human IgG.
Yibo Huang, Yujiro Higuchi, +3 authors, Kaoru Takegawa.
Sci Rep, 2018 Jan 13; 8(1). PMID: 29321565    Free PMC article.
Complement pathway gene activation and rising circulating immune complexes characterize early disease in HIV-associated tuberculosis.
Hanif Esmail, Rachel P Lai, +7 authors, Robert J Wilkinson.
Proc Natl Acad Sci U S A, 2018 Jan 18; 115(5). PMID: 29339504    Free PMC article.
Fc-Mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models.
Sai Kiran Sharma, Andrew Chow, +8 authors, Jason S Lewis.
Cancer Res, 2018 Jan 25; 78(7). PMID: 29363548    Free PMC article.
Highly Cited.
iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.
Xiaoping Qing, Yurii Chinenov, +9 authors, Jane E Salmon.
J Clin Invest, 2018 Jan 26; 128(4). PMID: 29369823    Free PMC article.
Evaluating antibody functional activity and strain-specificity of vaccine candidates for malaria in pregnancy using in vitro phagocytosis assays.
Mirja Hommel, Jo-Anne Chan, +4 authors, James G Beeson.
Parasit Vectors, 2018 Jan 31; 11(1). PMID: 29378634    Free PMC article.
Eradication of spontaneous malignancy by local immunotherapy.
Idit Sagiv-Barfi, Debra K Czerwinski, +4 authors, Ronald Levy.
Sci Transl Med, 2018 Feb 02; 10(426). PMID: 29386357    Free PMC article.
Highly Cited.
Augmentation of CD134 (OX40)-dependent NK anti-tumour activity is dependent on antibody cross-linking.
Anna H Turaj, Kerry L Cox, +10 authors, Sean H Lim.
Sci Rep, 2018 Feb 06; 8(1). PMID: 29396470    Free PMC article.
Mouse IgG2c Fc loop residues promote greater receptor-binding affinity than mouse IgG2b or human IgG1.
Daniel J Falconer, Adam W Barb.
PLoS One, 2018 Feb 07; 13(2). PMID: 29408873    Free PMC article.
Screening for key genes and transcription factors in ankylosing spondylitis by RNA-Seq.
Zhongyang Xu, Xiuyu Wang, Yanping Zheng.
Exp Ther Med, 2018 Feb 13; 15(2). PMID: 29434723    Free PMC article.
Role of Bruton's tyrosine kinase in B cells and malignancies.
Simar Pal Singh, Floris Dammeijer, Rudi W Hendriks.
Mol Cancer, 2018 Feb 20; 17(1). PMID: 29455639    Free PMC article.
Highly Cited. Review.
FcγRIIa defunctioning polymorphism in paediatric patients with renal allograft.
Fatina I Fadel, Manal F Elshamaa, +4 authors, Solaf Kamel.
Cent Eur J Immunol, 2018 Feb 24; 42(4). PMID: 29472814    Free PMC article.
Evaluation of analytical similarity between trastuzumab biosimilar CT-P6 and reference product using statistical analyses.
Jihun Lee, Hyun Ah Kang, +5 authors, Shin Jae Chang.
MAbs, 2018 Feb 28; 10(4). PMID: 29482416    Free PMC article.
Molecular Basis for the Recognition of Herpes Simplex Virus Type 1 Infection by Human Natural Killer Cells.
Hong-Sheng Dai, Michael A Caligiuri.
Front Immunol, 2018 Feb 28; 9. PMID: 29483911    Free PMC article.
Review.
Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues.
Kutty Selva Nandakumar.
Int J Mol Sci, 2018 Mar 03; 19(3). PMID: 29495570    Free PMC article.
Review.
Transmembrane domain dependent inhibitory function of FcγRIIB.
Junyi Wang, Zongyu Li, +2 authors, Wanli Liu.
Protein Cell, 2018 Mar 03; 9(12). PMID: 29497990    Free PMC article.
Review.
Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell-mediated cytotoxicity assay.
Justin Pollara, Chiara Orlandi, +11 authors, Guido Ferrari.
Cytometry A, 2018 Mar 03; 93(4). PMID: 29498807    Free PMC article.
Decreased IgG4 ACPA levels in responders and increased CD1c+ classical dendritic cells in non-responders of patients with rheumatoid arthritis under therapy.
Robby Engelmann, Sven Nekarda, +2 authors, Brigitte Müller-Hilke.
Clin Rheumatol, 2018 Mar 05; 37(7). PMID: 29502227
Natural killer cell cytotoxicity and its regulation by inhibitory receptors.
Santosh Kumar.
Immunology, 2018 Mar 08; 154(3). PMID: 29512837    Free PMC article.
Review.
Analysis of the association between Fc receptor family gene polymorphisms and ocular Behçet's disease in Han Chinese.
Donglei Zhang, Jieying Qin, +5 authors, Peizeng Yang.
Sci Rep, 2018 Mar 21; 8(1). PMID: 29555961    Free PMC article.
Correlation of natural autoantibodies and cardiovascular disease-related anti-bacterial antibodies in pericardial fluid of cardiac surgery patients.
D Simon, O Gilicze, +4 authors, T Berki.
Clin Exp Immunol, 2018 Mar 25; 193(1). PMID: 29573404    Free PMC article.
A Chimeric Antibody against ACKR3/CXCR7 in Combination with TMZ Activates Immune Responses and Extends Survival in Mouse GBM Models.
Nicole Salazar, Jeffrey C Carlson, +14 authors, Brian A Zabel.
Mol Ther, 2018 Apr 03; 26(5). PMID: 29606504    Free PMC article.
Antibody-Dependent Cellular Phagocytosis by Macrophages is a Novel Mechanism of Action of Elotuzumab.
Ahmed T Kurdi, Siobhan V Glavey, +14 authors, Irene M Ghobrial.
Mol Cancer Ther, 2018 Apr 15; 17(7). PMID: 29654064    Free PMC article.
IgG and leukocytes: Targets of immunomodulatory α2,6 sialic acids.
Mark B Jones.
Cell Immunol, 2018 Apr 25; 333. PMID: 29685495    Free PMC article.
Review.
Artificial Anti-Tumor Opsonizing Proteins with Fibronectin Scaffolds Engineered for Specificity to Each of the Murine FcγR Types.
Tiffany F Chen, Kevin K Li, +5 authors, K Dane Wittrup.
J Mol Biol, 2018 Apr 29; 430(12). PMID: 29704491    Free PMC article.
Multilayer Control of B Cell Activation by the B Cell Antigen Receptor: Following Themes Initiated With Bill Paul.
Anthony L DeFranco.
Front Immunol, 2018 May 10; 9. PMID: 29740430    Free PMC article.
Targeting B Cells and Plasma Cells in Autoimmune Diseases.
Katharina Hofmann, Ann-Katrin Clauder, Rudolf Armin Manz.
Front Immunol, 2018 May 10; 9. PMID: 29740441    Free PMC article.
Highly Cited. Review.
Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S.
Beatriz Trastoy, Erik Klontz, +4 authors, Marcelo E Guerin.
Nat Commun, 2018 May 16; 9(1). PMID: 29760474    Free PMC article.
Immunization With Fc-Based Recombinant Epstein-Barr Virus gp350 Elicits Potent Neutralizing Humoral Immune Response in a BALB/c Mice Model.
Bingchun Zhao, Xiao Zhang, +9 authors, Yixin Zeng.
Front Immunol, 2018 May 17; 9. PMID: 29765376    Free PMC article.
CD32-Expressing CD4 T Cells Are Phenotypically Diverse and Can Contain Proviral HIV DNA.
Genevieve E Martin, Matthew Pace, +15 authors, John Frater.
Front Immunol, 2018 May 22; 9. PMID: 29780387    Free PMC article.
Molecular and Functional Characterization of Fcγ Receptor IIIb-Ligand Interaction: Implications for Neutrophil-Mediated Immune Mechanisms in Malaria.
Piyapong Simtong, Amornrat V Romphruk, +8 authors, Sentot Santoso.
Infect Immun, 2018 May 23; 86(8). PMID: 29784860    Free PMC article.
Correlation of Lyme Disease-Associated IgG4 Autoantibodies With Synovial Pathology in Antibiotic-Refractory Lyme Arthritis.
Katherine B Sulka, Klemen Strle, +3 authors, Allen C Steere.
Arthritis Rheumatol, 2018 May 24; 70(11). PMID: 29790305    Free PMC article.
Potential of Murine IgG1 and Human IgG4 to Inhibit the Classical Complement and Fcγ Receptor Activation Pathways.
Gina-Maria Lilienthal, Johann Rahmöller, +3 authors, Marc Ehlers.
Front Immunol, 2018 Jun 06; 9. PMID: 29867943    Free PMC article.
Intracapillary immune complexes recruit and activate slan-expressing CD16+ monocytes in human lupus nephritis.
Florina Olaru, Thomas Döbel, +7 authors, Knut Schäkel.
JCI Insight, 2018 Jun 08; 3(11). PMID: 29875315    Free PMC article.
IGHG, IGKC, and FCGR genes and endogenous antibody responses to GARP in patients with breast cancer and matched controls.
Janardan P Pandey, Aryan M Namboodiri, +4 authors, Shoichiro Tsugane.
Hum Immunol, 2018 Jun 08; 79(8). PMID: 29879453    Free PMC article.
Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T Cell Antigens.
Jeremy D Waight, Dhan Chand, +14 authors, Nicholas S Wilson.
Cancer Cell, 2018 Jun 13; 33(6). PMID: 29894690    Free PMC article.
Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection.
Jason D Simmons, Catherine M Stein, +9 authors, Thomas R Hawn.
Nat Rev Immunol, 2018 Jun 14; 18(9). PMID: 29895826    Free PMC article.
Highly Cited. Review.
The promise and challenges of immune agonist antibody development in cancer.
Patrick A Mayes, Kenneth W Hance, Axel Hoos.
Nat Rev Drug Discov, 2018 Jun 16; 17(7). PMID: 29904196
Highly Cited. Review.
Sialylated Autoantigen-Reactive IgG Antibodies Attenuate Disease Development in Autoimmune Mouse Models of Lupus Nephritis and Rheumatoid Arthritis.
Yannic C Bartsch, Johann Rahmöller, +17 authors, Marc Ehlers.
Front Immunol, 2018 Jun 22; 9. PMID: 29928274    Free PMC article.
Tissue-Specific Expression of the Low-Affinity IgG Receptor, FcγRIIb, on Human Mast Cells.
Oliver T Burton, Alexandra Epp, +6 authors, Hans C Oettgen.
Front Immunol, 2018 Jun 22; 9. PMID: 29928276    Free PMC article.
Extending human IgG half-life using structure-guided design.
Brian J Booth, Boopathy Ramakrishnan, +4 authors, Karthik Viswanathan.
MAbs, 2018 Jun 28; 10(7). PMID: 29947573    Free PMC article.
Size-Dependent Segregation Controls Macrophage Phagocytosis of Antibody-Opsonized Targets.
Matthew H Bakalar, Aaron M Joffe, +3 authors, Daniel A Fletcher.
Cell, 2018 Jun 30; 174(1). PMID: 29958103    Free PMC article.
Highly Cited.
Anti-ADAM17 monoclonal antibody MEDI3622 increases IFNγ production by human NK cells in the presence of antibody-bound tumor cells.
Hemant K Mishra, Nabendu Pore, Emil F Michelotti, Bruce Walcheck.
Cancer Immunol Immunother, 2018 Jul 07; 67(9). PMID: 29978334    Free PMC article.
Effects of Bovine Immunoglobulins on Immune Function, Allergy, and Infection.
Laurien H Ulfman, Jeanette H W Leusen, +2 authors, R J Joost van Neerven.
Front Nutr, 2018 Jul 11; 5. PMID: 29988421    Free PMC article.
Review.
Analysis of protein-protein interaction network based on transcriptome profiling of ovine granulosa cells identifies candidate genes in cyclic recruitment of ovarian follicles.
Reza Talebi, Ahmad Ahmadi, Fazlollah Afraz.
J Anim Sci Technol, 2018 Jul 12; 60. PMID: 29992036    Free PMC article.
Evaluating Anti-CD32b F(ab) Conformation Using Molecular Dynamics and Small-Angle X-Ray Scattering.
Emma J Sutton, Richard T Bradshaw, +6 authors, Jonathan W Essex.
Biophys J, 2018 Jul 19; 115(2). PMID: 30021105    Free PMC article.
Kaposi's Sarcoma-Associated Herpesvirus Latency Locus Renders B Cells Hyperresponsive to Secondary Infections.
Sang-Hoon Sin, Anthony B Eason, +7 authors, Dirk P Dittmer.
J Virol, 2018 Jul 20; 92(19). PMID: 30021906    Free PMC article.
T-Bet+ IgM Memory Cells Generate Multi-lineage Effector B Cells.
Kevin J Kenderes, Russell C Levack, +3 authors, Gary M Winslow.
Cell Rep, 2018 Jul 26; 24(4). PMID: 30044980    Free PMC article.
Higher Serum Immunoglobulin G3 Levels May Predict the Development of Multiple Sclerosis in Individuals With Clinically Isolated Syndrome.
Stephanie Trend, Anderson P Jones, +10 authors, Prue H Hart.
Front Immunol, 2018 Jul 31; 9. PMID: 30057580    Free PMC article.
Aggregates of IVIG or Avastin, but not HSA, modify the response to model innate immune response modulating impurities.
Swamy Kumar Polumuri, Lydia A Haile, Derek D C Ireland, Daniela Verthelyi.
Sci Rep, 2018 Aug 02; 8(1). PMID: 30065306    Free PMC article.
Characterization of peritoneal cells from cats with experimentally-induced feline infectious peritonitis (FIP) using RNA-seq.
Rie Watanabe, Christina Eckstrand, Hongwei Liu, Niels C Pedersen.
Vet Res, 2018 Aug 09; 49(1). PMID: 30086792    Free PMC article.
Circulating and intrahepatic antiviral B cells are defective in hepatitis B.
Alice R Burton, Laura J Pallett, +11 authors, Mala K Maini.
J Clin Invest, 2018 Aug 10; 128(10). PMID: 30091725    Free PMC article.
Highly Cited.
The DNA-polymorphism rs849142 is associated with skin toxicity induced by targeted anti-EGFR therapy using cetuximab.
Matthias F Froelich, Sebastian Stintzing, +5 authors, Andreas Jung.
Oncotarget, 2018 Aug 14; 9(54). PMID: 30100989    Free PMC article.
Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors.
Natalia A Kuzmina, Patrick Younan, +8 authors, Alexander Bukreyev.
Cell Rep, 2018 Aug 16; 24(7). PMID: 30110637    Free PMC article.
The protein tyrosine phosphatase PTPN22 negatively regulates presentation of immune complex derived antigens.
Fiona Clarke, Harriet A Purvis, +5 authors, Andrew P Cope.
Sci Rep, 2018 Aug 25; 8(1). PMID: 30139951    Free PMC article.
Sex Differences in HIV Infection: Mystique Versus Machismo.
Eileen P Scully.
Pathog Immun, 2018 Aug 25; 3(1). PMID: 30140783    Free PMC article.
Chemoenzymatic Methods for the Synthesis of Glycoproteins.
Chao Li, Lai-Xi Wang.
Chem Rev, 2018 Aug 25; 118(17). PMID: 30141327    Free PMC article.
Highly Cited. Review.
Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cells.
Melissa Newling, Willianne Hoepel, +11 authors, Esther C de Jong.
Eur J Immunol, 2018 Sep 06; 48(11). PMID: 30184252    Free PMC article.
Overexpression of CD64 on CD14++CD16- and CD14++CD16+ monocytes of rheumatoid arthritis patients correlates with disease activity.
Qing Luo, Pengcheng Xiao, +7 authors, Junming Li.
Exp Ther Med, 2018 Sep 14; 16(3). PMID: 30210612    Free PMC article.
CD38 Antibodies in Multiple Myeloma: Mechanisms of Action and Modes of Resistance.
Niels W C J van de Donk, Saad Z Usmani.
Front Immunol, 2018 Oct 09; 9. PMID: 30294326    Free PMC article.
Highly Cited. Review.
Adjuvanted Immunotherapy Approaches for Peanut Allergy.
Brandi T Johnson-Weaver, Herman F Staats, A Wesley Burks, Michael D Kulis.
Front Immunol, 2018 Oct 16; 9. PMID: 30319619    Free PMC article.
Review.
A phosphatidylinositol 4,5-bisphosphate redistribution-based sensing mechanism initiates a phagocytosis programing.
Libing Mu, Zhongyuan Tu, +12 authors, Yan Shi.
Nat Commun, 2018 Oct 17; 9(1). PMID: 30323235    Free PMC article.
Antibody-mediated protection against Ebola virus.
Erica Ollmann Saphire, Sharon L Schendel, +2 authors, Galit Alter.
Nat Immunol, 2018 Oct 20; 19(11). PMID: 30333617    Free PMC article.
Highly Cited. Review.
Ligand Recognition Determines the Role of Inhibitory B Cell Co-receptors in the Regulation of B Cell Homeostasis and Autoimmunity.
Takeshi Tsubata.
Front Immunol, 2018 Oct 20; 9. PMID: 30333834    Free PMC article.
Review.
Tregitope-linked Refined Allergen Vaccines for Immunotherapy in Cockroach Allergy.
Pannathee Prangtaworn, Urai Chaisri, +7 authors, Nitat Sookrung.
Sci Rep, 2018 Oct 21; 8(1). PMID: 30341299    Free PMC article.
CD32 Expression is not Associated to HIV-DNA content in CD4 cell subsets of individuals with Different Levels of HIV Control.
Marcial García, María Angeles Navarrete-Muñoz, +11 authors, Norma Rallón.
Sci Rep, 2018 Oct 21; 8(1). PMID: 30341387    Free PMC article.
Critical Role of Macrophage FcγR Signaling and Reactive Oxygen Species in Alloantibody-Mediated Hepatocyte Rejection.
Jason M Zimmerer, Xin L Liu, +4 authors, Ginny L Bumgardner.
J Immunol, 2018 Nov 07; 201(12). PMID: 30397035    Free PMC article.
Targeted Intracellular Delivery of Antibodies: The State of the Art.
Tatiana A Slastnikova, A V Ulasov, A A Rosenkranz, A S Sobolev.
Front Pharmacol, 2018 Nov 09; 9. PMID: 30405420    Free PMC article.
Review.
IgG Glyco-Engineering to Improve IVIg Potency.
Christine W Bruggeman, Gillian Dekkers, +5 authors, Taco W Kuijpers.
Front Immunol, 2018 Nov 09; 9. PMID: 30405631    Free PMC article.
Generation of Highly Efficient Equine-Derived Antibodies for Post-Exposure Treatment of Ricin Intoxications by Vaccination with Monomerized Ricin.
Reut Falach, Anita Sapoznikov, +9 authors, Yoav Gal.
Toxins (Basel), 2018 Nov 15; 10(11). PMID: 30424519    Free PMC article.
Altered circulating levels of B cell growth factors and their modulation upon anti-tuberculosis treatment in pulmonary tuberculosis and tuberculous lymphadenitis.
Gokul Raj Kathamuthu, Kadar Moideen, +4 authors, Subash Babu.
PLoS One, 2018 Nov 15; 13(11). PMID: 30427928    Free PMC article.
The Development of Serum Amyloid P as a Possible Therapeutic.
Darrell Pilling, Richard H Gomer.
Front Immunol, 2018 Nov 22; 9. PMID: 30459752    Free PMC article.
Review.
Fucosyl-Agalactosyl IgG₁ Induces Cholangiocarcinoma Metastasis and Early Recurrence by Activating Tumor-Associated Macrophage.
Ting-Tsung Chang, Hung-Wen Tsai, Cheng-Hsun Ho.
Cancers (Basel), 2018 Nov 25; 10(11). PMID: 30469416    Free PMC article.
Pentraxins and Fc Receptor-Mediated Immune Responses.
Jinghua Lu, Carolyn Mold, Terry W Du Clos, Peter D Sun.
Front Immunol, 2018 Nov 30; 9. PMID: 30483265    Free PMC article.
Review.
Gene Regulatory Network Modeling of Macrophage Differentiation Corroborates the Continuum Hypothesis of Polarization States.
Alessandro Palma, Abdul Salam Jarrah, +2 authors, Filippo Castiglione.
Front Physiol, 2018 Dec 14; 9. PMID: 30546316    Free PMC article.
Landscape of B cell immunity and related immune evasion in human cancers.
Xihao Hu, Jian Zhang, +17 authors, X Shirley Liu.
Nat Genet, 2019 Feb 12; 51(3). PMID: 30742113    Free PMC article.
Highly Cited.
Role of ADAM17 as a regulatory checkpoint of CD16A in NK cells and as a potential target for cancer immunotherapy.
Jianming Wu, Hemant K Mishra, Bruce Walcheck.
J Leukoc Biol, 2019 Feb 21; 105(6). PMID: 30786043    Free PMC article.
Highly Cited. Review.
Antibody responses to viral infections: a structural perspective across three different enveloped viruses.
Charles D Murin, Ian A Wilson, Andrew B Ward.
Nat Microbiol, 2019 Mar 20; 4(5). PMID: 30886356    Free PMC article.
Review.
Decreased expression of FcγRII in active Graves' disease patients.
Xixuan Lu, Shiqiao Peng, +2 authors, Weiping Teng.
J Clin Lab Anal, 2019 Apr 30; 33(6). PMID: 31033004    Free PMC article.
Asparaginase immune complexes induce Fc-γRIII-dependent hypersensitivity in naive mice.
Sanjay Rathod, Manda Ramsey, +3 authors, Christian A Fernandez.
FASEB J, 2019 Jul 10; 33(10). PMID: 31284767    Free PMC article.
Effects of BTK signalling in pathogenic microorganism infections.
Bingjue Ye, Cheng Zhou, Huiting Guo, Min Zheng.
J Cell Mol Med, 2019 Aug 10; 23(10). PMID: 31397086    Free PMC article.
Review.
Dual effects of an anti-CD147 antibody for Esophageal cancer therapy.
Miao Wang, Shuai Zhang, +6 authors, Yu Li.
Cancer Biol Ther, 2019 Aug 15; 20(12). PMID: 31411555    Free PMC article.
Fc Gamma Receptor Polymorphisms Modulated the Vaccine Effect on HIV-1 Risk in the HVTN 505 HIV Vaccine Trial.
Shuying S Li, Peter B Gilbert, +21 authors, Xinxia Peng.
J Virol, 2019 Aug 23; 93(21). PMID: 31434737    Free PMC article.
A distinct subset of FcγRI-expressing Th1 cells exert antibody-mediated cytotoxic activity.
Diana Rasoulouniriana, Nadine Santana-Magal, +11 authors, Yaron Carmi.
J Clin Invest, 2019 Aug 27; 129(10). PMID: 31449054    Free PMC article.
Understudied Factors Influencing Fc-Mediated Immune Responses against Viral Infections.
Sai Priya Anand, Andrés Finzi.
Vaccines (Basel), 2019 Sep 05; 7(3). PMID: 31480293    Free PMC article.
Review.
HIV and Solid Organ Transplantation: Where Are we Now.
Jean Botha, June Fabian, +2 authors, Caroline T Tiemessen.
Curr HIV/AIDS Rep, 2019 Sep 05; 16(5). PMID: 31482298    Free PMC article.
Review.
Ehrlichia chaffeensis Outer Membrane Protein 1-Specific Human Antibody-Mediated Immunity Is Defined by Intracellular TRIM21-Dependent Innate Immune Activation and Extracellular Neutralization.
Thangam Sudha Velayutham, Sandeep Kumar, +5 authors, Jere W McBride.
Infect Immun, 2019 Sep 25; 87(12). PMID: 31548319    Free PMC article.
Differential Effect of Mucosal NKp44+ Innate Lymphoid Cells and Δγ Cells on Simian Immunodeficiency Virus Infection Outcome in Rhesus Macaques.
Mohammad Arif Rahman, Eun-Ju Ko, +6 authors, Marjorie Robert-Guroff.
J Immunol, 2019 Sep 27; 203(9). PMID: 31554692    Free PMC article.
Mechanisms of Resistance to Monoclonal Antibodies (mAbs) in Lymphoid Malignancies.
Pallawi Torka, Mathew Barth, Robert Ferdman, Francisco J Hernandez-Ilizaliturri.
Curr Hematol Malig Rep, 2019 Sep 29; 14(5). PMID: 31559580
Review.
IGFBP2 promotes immunosuppression associated with its mesenchymal induction and FcγRIIB phosphorylation in glioblastoma.
Yunmian Liu, Chunyan Song, +2 authors, Sonya Wei Song.
PLoS One, 2019 Sep 29; 14(9). PMID: 31560714    Free PMC article.
Identification of key genes and pathways associated with different immune statuses of hepatitis B virus infection.
Jinglan Jin, Hongqin Xu, +4 authors, Junqi Niu.
J Cell Mol Med, 2019 Oct 01; 23(11). PMID: 31565863    Free PMC article.
Fcγ receptors and toll-like receptor 9 synergize to drive immune complex-induced dendritic cell maturation.
Nicole L J Nelson, Cheryl M Zajd, Michelle R Lennartz, Edmund J Gosselin.
Cell Immunol, 2019 Oct 05; 345. PMID: 31582169    Free PMC article.
The Role of Immune Checkpoint Receptors in Regulating Immune Reactivity in Lupus.
Kun-Lin Lu, Ming-Ying Wu, +4 authors, Chun-Bing Chen.
Cells, 2019 Oct 11; 8(10). PMID: 31597242    Free PMC article.
Review.
Human Monoclonal Antibodies as Adjuvant Treatment of Chronic Hepatitis B Virus Infection.
Antonella Cerino, Stefania Mantovani, +3 authors, Mario U Mondelli.
Front Immunol, 2019 Oct 15; 10. PMID: 31608071    Free PMC article.
NK Cell-Fc Receptors Advance Tumor Immunotherapy.
Emilio Sanseviero.
J Clin Med, 2019 Oct 17; 8(10). PMID: 31614774    Free PMC article.
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Genetic Variation in Low-To-Medium-Affinity Fcγ Receptors: Functional Consequences, Disease Associations, and Opportunities for Personalized Medicine.
Sietse Q Nagelkerke, David E Schmidt, Masja de Haas, Taco W Kuijpers.
Front Immunol, 2019 Oct 22; 10. PMID: 31632391    Free PMC article.
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Tumor-binding antibodies induce potent dendritic cell-mediated tumor immunity.
Yaron Carmi, Tyler Prestwood, Edgar G Engleman.
Oncoimmunology, 2018 May 07; 8(10). PMID: 31646066    Free PMC article.
The Complex Association of FcγRIIb With Autoimmune Susceptibility.
J Sjef Verbeek, Sachiko Hirose, Hiroyuki Nishimura.
Front Immunol, 2019 Nov 05; 10. PMID: 31681256    Free PMC article.
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Effect of Rhus verniciflua Extract on IgE-Antigen-Mediated Allergic Reaction in Rat Basophilic Leukemic RBL-2H3 Mast Cells and Passive Cutaneous Anaphylaxis in Mice.
Hyun Ju Do, Yeo Jin Hwang, Hye Jin Yang, Kwang Il Park.
Evid Based Complement Alternat Med, 2019 Nov 07; 2019. PMID: 31687037    Free PMC article.
Proteoform-Resolved FcɤRIIIa Binding Assay for Fab Glycosylated Monoclonal Antibodies Achieved by Affinity Chromatography Mass Spectrometry of Fc Moieties.
Steffen Lippold, Simone Nicolardi, Manfred Wuhrer, David Falck.
Front Chem, 2019 Nov 12; 7. PMID: 31709228    Free PMC article.
Boosting therapeutic potency of antibodies by taming Fc domain functions.
Tae Hyun Kang, Sang Taek Jung.
Exp Mol Med, 2019 Nov 19; 51(11). PMID: 31735912    Free PMC article.
Review.
Impaired Antibody-Independent Immune Response of B Cells in Patients With Acute Dengue Infection.
Vinit Upasani, Hoa Thi My Vo, +9 authors, Tineke Cantaert.
Front Immunol, 2019 Nov 19; 10. PMID: 31736948    Free PMC article.
Lupus-like Disease in FcγRIIB-/- Mice Induces Osteopenia.
Peerapat Visitchanakun, Worasit Saiworn, +3 authors, Sutada Lotinun.
Sci Rep, 2019 Nov 24; 9(1). PMID: 31758072    Free PMC article.
Differential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody-dependent (AD) NK cell activation and ADCC.
Irene Lisovsky, Sanket Kant, +8 authors, Nicole F Bernard.
J Leukoc Biol, 2019 Jan 31; 105(3). PMID: 30698860    Free PMC article.
Regulation of macrophage activity by surface receptors contained within Borrelia burgdorferi-enriched phagosomal fractions.
Ana Carreras-González, Diego Barriales, +18 authors, Juan Anguita.
PLoS Pathog, 2019 Nov 19; 15(11). PMID: 31738806    Free PMC article.
Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-μTP-L309C, a recombinant IgG1 Fc hexamer.
Bonnie J B Lewis, Jade Ville, +5 authors, Donald R Branch.
BMC Immunol, 2019 Dec 06; 20(1). PMID: 31801459    Free PMC article.
Geometrical reorganization of Dectin-1 and TLR2 on single phagosomes alters their synergistic immune signaling.
Wenqian Li, Jun Yan, Yan Yu.
Proc Natl Acad Sci U S A, 2019 Nov 23; 116(50). PMID: 31754039    Free PMC article.
Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor.
Chunshu Yang, Xiaoyu Hou, +4 authors, Pingting Yang.
J Transl Med, 2019 Dec 23; 17(1). PMID: 31864410    Free PMC article.
Harnessing MerTK agonism for targeted therapeutics.
Vivekananda Kedage, Diego Ellerman, +4 authors, Minhong Yan.
MAbs, 2019 Dec 20; 12(1). PMID: 31852344    Free PMC article.
Desperately Seeking Therapies for Cerebral Malaria.
Brittany A Riggle, Louis H Miller, Susan K Pierce.
J Immunol, 2020 Jan 08; 204(2). PMID: 31907275    Free PMC article.
Review.
Termination of immune activation: an essential component of healthy host immune responses.
Barry A Kane, Katherine J Bryant, H Patrick McNeil, Nicodemus T Tedla.
J Innate Immun, 2014 Jul 19; 6(6). PMID: 25033984    Free PMC article.
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IgA subclasses have different effector functions associated with distinct glycosylation profiles.
Ulrike Steffen, Carolien A Koeleman, +19 authors, Georg Schett.
Nat Commun, 2020 Jan 09; 11(1). PMID: 31913287    Free PMC article.
Antibody-Dependent Cellular Cytotoxicity (ADCC)-Mediating Antibodies Constrain Neutralizing Antibody Escape Pathway.
Dieter Mielke, Gama Bandawe, +14 authors, Carolyn Williamson.
Front Immunol, 2020 Jan 11; 10. PMID: 31921139    Free PMC article.
Update on Fc-Mediated Antibody Functions Against HIV-1 Beyond Neutralization.
Bin Su, Stefania Dispinseri, +6 authors, Christiane Moog.
Front Immunol, 2020 Jan 11; 10. PMID: 31921207    Free PMC article.
Review.
Engineering the interactions between a plant-produced HIV antibody and human Fc receptors.
Szymon Stelter, Mathew J Paul, +7 authors, Julian K-C Ma.
Plant Biotechnol J, 2019 Jul 14; 18(2). PMID: 31301102    Free PMC article.
Fcγ Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita.
Balint Kovacs, Jenny Tillmann, +6 authors, Jörg Köhl.
Front Immunol, 2020 Jan 30; 10. PMID: 31993051    Free PMC article.
Minimal B Cell Extrinsic IgG Glycan Modifications of Pro- and Anti-Inflammatory IgG Preparations in vivo.
Anja Schaffert, Maja Hanić, +10 authors, Falk Nimmerjahn.
Front Immunol, 2020 Jan 31; 10. PMID: 31998308    Free PMC article.
Phagocytosis checkpoints as new targets for cancer immunotherapy.
Mingye Feng, Wen Jiang, +3 authors, Irving L Weissman.
Nat Rev Cancer, 2019 Aug 30; 19(10). PMID: 31462760    Free PMC article.
Highly Cited. Review.
Receptor targeting drug delivery strategies and prospects in the treatment of rheumatoid arthritis.
Jaber Emami, Zahra Ansarypour.
Res Pharm Sci, 2020 Feb 11; 14(6). PMID: 32038727    Free PMC article.
Review.
Factor VIII Fc Fusion Protein but not FVIII Drives Human Monocyte-Derived Dendritic Cell Activation via FcγRIIa.
Christoph Kannicht, Ilona Danßmann, +3 authors, Henriette Geyer.
Hemasphere, 2020 Feb 20; 4(1). PMID: 32072146    Free PMC article.
IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints.
Sudeepta Kumar Panda, Gustaf Wigerblad, +8 authors, Fredrik Wermeling.
Proc Natl Acad Sci U S A, 2020 Jan 26; 117(6). PMID: 31980518    Free PMC article.
Predominant Role of Immunoglobulin G in the Pathogenesis of Splenomegaly in Murine Lupus.
Qian Zhang, Liping Xiang, +3 authors, Guo-Min Deng.
Front Immunol, 2020 Feb 23; 10. PMID: 32082297    Free PMC article.
Elimination of activating Fcγ receptors in spontaneous autoimmune peripheral polyneuropathy model protects from neuropathic disease.
Gang Zhang, Nataliia Bogdanova, Tong Gao, Kazim A Sheikh.
PLoS One, 2019 Aug 16; 14(8). PMID: 31415574    Free PMC article.
CEACAM3-A Prim(at)e Invention for Opsonin-Independent Phagocytosis of Bacteria.
Patrizia Bonsignore, Johannes W P Kuiper, +2 authors, Christof R Hauck.
Front Immunol, 2020 Mar 03; 10. PMID: 32117212    Free PMC article.
Review.
Recombinant Factor VIII Fc Inhibits B Cell Activation via Engagement of the FcγRIIB Receptor.
Maria T Georgescu, Paul C Moorehead, +4 authors, David Lillicrap.
Front Immunol, 2020 Mar 03; 11. PMID: 32117285    Free PMC article.
Probe Signal Values in mRNA Arrays Imply an Excessive Involvement of Neutrophil FCGR1 in Tuberculosis.
Kang Wu, Meng Li, +2 authors, Xiao-Yong Fan.
Front Med (Lausanne), 2020 Mar 03; 7. PMID: 32118006    Free PMC article.
Tumour Necrosis Factor-α Inhibition Improves Stroke Outcome in a Mouse Model of Rheumatoid Arthritis.
N R Bonetti, C Diaz-Cañestro, +11 authors, G G Camici.
Sci Rep, 2019 Feb 20; 9(1). PMID: 30778120    Free PMC article.
Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes.
Christian Rungsted Andersson, Jeppe Falsig, +5 authors, Jan Torleif Pedersen.
Sci Rep, 2019 Mar 16; 9(1). PMID: 30874605    Free PMC article.
Patients with common variable immunodeficiency with autoimmune cytopenias exhibit hyperplastic yet inefficient germinal center responses.
Neil Romberg, Carole Le Coz, +17 authors, Eric Meffre.
J Allergy Clin Immunol, 2018 Jun 24; 143(1). PMID: 29935219    Free PMC article.
TLR9-mediated activation of dendritic cells by CD32 targeting for the generation of highly immunostimulatory vaccines.
J A Sepulveda-Toepfer, Johannes Pichler, +5 authors, Geert Cornelius Mudde.
Hum Vaccin Immunother, 2018 Aug 30; 15(1). PMID: 30156957    Free PMC article.
Humanised effector-null FcγRIIA antibody inhibits immune complex-mediated proinflammatory responses.
Bo Chen, Katherine A Vousden, +28 authors, Gary P Sims.
Ann Rheum Dis, 2018 Nov 22; 78(2). PMID: 30459279    Free PMC article.
OMIP-051 - 28-color flow cytometry panel to characterize B cells and myeloid cells.
Thomas Liechti, Mario Roederer.
Cytometry A, 2018 Dec 15; 95(2). PMID: 30549419    Free PMC article.
CD32 Ligation Promotes the Activation of CD4+ T Cells.
María Pía Holgado, Inés Sananez, +2 authors, Lourdes Arruvito.
Front Immunol, 2018 Dec 18; 9. PMID: 30555482    Free PMC article.
The genomic organization and expression pattern of the low-affinity Fc gamma receptors (FcγR) in the Göttingen minipig.
Jerome Egli, Roland Schmucki, +6 authors, Antonio Iglesias.
Immunogenetics, 2018 Dec 20; 71(2). PMID: 30564855    Free PMC article.
AS03-Adjuvanted H5N1 Avian Influenza Vaccine Modulates Early Innate Immune Signatures in Human Peripheral Blood Mononuclear Cells.
Leigh M Howard, Johannes B Goll, +8 authors, Kathryn M Edwards.
J Infect Dis, 2018 Dec 20; 219(11). PMID: 30566602    Free PMC article.
Expression of a Recombinant High Affinity IgG Fc Receptor by Engineered NK Cells as a Docking Platform for Therapeutic mAbs to Target Cancer Cells.
Kristin M Snyder, Robert Hullsiek, +6 authors, Bruce Walcheck.
Front Immunol, 2018 Dec 24; 9. PMID: 30574146    Free PMC article.
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody.
Danbee Ha, Atsushi Tanaka, +10 authors, Shimon Sakaguchi.
Proc Natl Acad Sci U S A, 2018 Dec 28; 116(2). PMID: 30587582    Free PMC article.
Lupus-Associated Immune Complexes Activate Human Neutrophils in an FcγRIIA-Dependent but TLR-Independent Response.
Ramon G Bonegio, Jessica D Lin, +3 authors, Kei Yasuda.
J Immunol, 2019 Jan 06; 202(3). PMID: 30610165    Free PMC article.
Human neutrophils express low levels of FcγRIIIA, which plays a role in PMN activation.
Josée Golay, Rut Valgardsdottir, +3 authors, Martino Introna.
Blood, 2019 Jan 19; 133(13). PMID: 30655272    Free PMC article.
Multi-isotype Glycoproteomic Characterization of Serum Antibody Heavy Chains Reveals Isotype- and Subclass-Specific N-Glycosylation Profiles.
Kevin Brown Chandler, Nickita Mehta, +3 authors, Catherine E Costello.
Mol Cell Proteomics, 2019 Jan 20; 18(4). PMID: 30659065    Free PMC article.
Fc gamma RIIb expression levels in human liver sinusoidal endothelial cells during progression of non-alcoholic fatty liver disease.
Tomoko Ishikawa, Hiroshi Yokoyama, Tomokazu Matsuura, Yoko Fujiwara.
PLoS One, 2019 Jan 30; 14(1). PMID: 30695042    Free PMC article.
The Impact of FcγRI Binding on Immuno-PET.
Delphine Vivier, Sai Kiran Sharma, +3 authors, Brian M Zeglis.
J Nucl Med, 2019 Feb 09; 60(8). PMID: 30733320    Free PMC article.
Current Strategies to Inhibit High Affinity FcεRI-Mediated Signaling for the Treatment of Allergic Disease.
Gregorio Gomez.
Front Immunol, 2019 Feb 23; 10. PMID: 30792720    Free PMC article.
Review.
Bridging Vaccine-Induced HIV-1 Neutralizing and Effector Antibody Responses in Rabbit and Rhesus Macaque Animal Models.
Justin Pollara, Dorothy I Jones, +14 authors, Sallie R Permar.
J Virol, 2019 Mar 08; 93(10). PMID: 30842326    Free PMC article.
Infection-Induced Resistance to Experimental Cerebral Malaria Is Dependent Upon Secreted Antibody-Mediated Inhibition of Pathogenic CD8+ T Cell Responses.
Tovah N Shaw, Colette A Inkson, +6 authors, Kevin N Couper.
Front Immunol, 2019 Mar 09; 10. PMID: 30846985    Free PMC article.
Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis.
Tomas Castro-Dopico, Thomas W Dennison, +13 authors, Menna R Clatworthy.
Immunity, 2019 Mar 17; 50(4). PMID: 30876876    Free PMC article.
Highly Cited.
Integrin β1 Promotes the Interaction of Murine IgG3 with Effector Cells.
Carolyn Saylor Hawk, Carolina Coelho, +11 authors, Arturo Casadevall.
J Immunol, 2019 Mar 22; 202(9). PMID: 30894426    Free PMC article.
Important roles of CD32 in promoting suppression of IL-4 induced immune responses by a novel anti-IL-4Rα therapeutic antibody.
Jie Zhao, Liangfeng Jiang, +8 authors, Haomin Huang.
MAbs, 2019 Apr 06; 11(5). PMID: 30950681    Free PMC article.
Contribution of Fcγ Receptor-Mediated Immunity to the Pathogenesis Caused by the Human Respiratory Syncytial Virus.
Orlando A Acevedo, Fabián E Díaz, +5 authors, Alexis M Kalergis.
Front Cell Infect Microbiol, 2019 Apr 16; 9. PMID: 30984626    Free PMC article.
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Systems serology for decoding infection and vaccine-induced antibody responses to HIV-1.
Srivamshi Pittala, Kyle S Morrison, Margaret E Ackerman.
Curr Opin HIV AIDS, 2019 Apr 30; 14(4). PMID: 31033729    Free PMC article.
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Fc-Fusion Drugs Have FcγR/C1q Binding and Signaling Properties That May Affect Their Immunogenicity.
H A Daniel Lagassé, Hartmut Hengel, Basil Golding, Zuben E Sauna.
AAPS J, 2019 May 08; 21(4). PMID: 31062128
B Cell Fcγ Receptor IIb Modulates Atherosclerosis in Male and Female Mice by Controlling Adaptive Germinal Center and Innate B-1-Cell Responses.
Jayashree Bagchi-Chakraborty, Anna Francis, +12 authors, Andrew P Sage.
Arterioscler Thromb Vasc Biol, 2019 May 17; 39(7). PMID: 31092015    Free PMC article.
Optimization of 4-1BB antibody for cancer immunotherapy by balancing agonistic strength with FcγR affinity.
Xinyue Qi, Fanlin Li, +4 authors, Xuanming Yang.
Nat Commun, 2019 May 21; 10(1). PMID: 31105267    Free PMC article.
Combinatorial diversity of Syk recruitment driven by its multivalent engagement with FcεRIγ.
Timothy Travers, William K Kanagy, +6 authors, S Gnanakaran.
Mol Biol Cell, 2019 Jun 20; 30(17). PMID: 31216232    Free PMC article.
NK cell-intrinsic FcεRIγ limits CD8+ T-cell expansion and thereby turns an acute into a chronic viral infection.
Vikas Duhan, Thamer A Hamdan, +10 authors, Karl S Lang.
PLoS Pathog, 2019 Jun 21; 15(6). PMID: 31220194    Free PMC article.
C-reactive protein (CRP) promotes malignant properties in pancreatic neuroendocrine neoplasms.
Simon Schimmack, Yongchao Yang, +6 authors, Oliver Strobel.
Endocr Connect, 2019 Jun 25; 8(7). PMID: 31234146    Free PMC article.
Zika Virus-Immune Plasmas from Symptomatic and Asymptomatic Individuals Enhance Zika Pathogenesis in Adult and Pregnant Mice.
Byoung-Shik Shim, Young-Chan Kwon, +13 authors, Hyeryun Choe.
mBio, 2019 Jul 04; 10(4). PMID: 31266863    Free PMC article.
Transient and chronic childhood immune thrombocytopenia are distinctly affected by Fc-γ receptor polymorphisms.
David E Schmidt, Katja M J Heitink-Pollé, +8 authors, Masja de Haas.
Blood Adv, 2019 Jul 05; 3(13). PMID: 31270082    Free PMC article.
Glycoform-resolved FcɣRIIIa affinity chromatography-mass spectrometry.
Steffen Lippold, Simone Nicolardi, +6 authors, David Falck.
MAbs, 2019 Jul 06; 11(7). PMID: 31276431    Free PMC article.
Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor.
Xiaoyang Liu, Senthilkumar Palaniyandi, +7 authors, Xiaoping Zhu.
Nat Commun, 2019 Jul 11; 10(1). PMID: 31289263    Free PMC article.
IFN-mediated negative feedback supports bacteria class-specific macrophage inflammatory responses.
Rachel A Gottschalk, Michael G Dorrington, +8 authors, Ronald N Germain.
Elife, 2019 Aug 07; 8. PMID: 31385572    Free PMC article.
TRIM21-From Intracellular Immunity to Therapy.
Stian Foss, Maria Bottermann, +3 authors, Jan Terje Andersen.
Front Immunol, 2019 Sep 27; 10. PMID: 31555278    Free PMC article.
Review.
Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology.
Annerieke Sierksma, Ashley Lu, +8 authors, Mark Fiers.
EMBO Mol Med, 2020 Jan 18; 12(3). PMID: 31951107    Free PMC article.
Fc Glycan-Mediated Regulation of Placental Antibody Transfer.
Madeleine F Jennewein, Ilona Goldfarb, +20 authors, Galit Alter.
Cell, 2019 Jun 18; 178(1). PMID: 31204102    Free PMC article.
Boosting of Markers of Fcγ Receptor Function in Anti-HIV Antibodies During Structured Treatment Interruption.
Hugh Billings, Bruce D Wines, +4 authors, P Mark Hogarth.
AIDS Res Hum Retroviruses, 2019 Jul 11; 35(9). PMID: 31288562    Free PMC article.
Antibody-Mediated Porcine Reproductive and Respiratory Syndrome Virus Infection Downregulates the Production of Interferon-α and Tumor Necrosis Factor-α in Porcine Alveolar Macrophages via Fc Gamma Receptor I and III.
Liujun Zhang, Wen Li, +4 authors, Gaiping Zhang.
Viruses, 2020 Feb 13; 12(2). PMID: 32046249    Free PMC article.
Fc-Linked IgG N-Glycosylation in FcγR Knock-Out Mice.
Olga O Zaytseva, Michaela Seeling, +3 authors, Falk Nimmerjahn.
Front Cell Dev Biol, 2020 Mar 21; 8. PMID: 32195245    Free PMC article.
High-resolution quantification of discrete phagocytic events by live cell time-lapse high-content microscopy imaging.
Charles C Chu, Jonathan J Pinney, +4 authors, Michael R Elliott.
J Cell Sci, 2020 Feb 02; 133(5). PMID: 32005699    Free PMC article.
Monocyte procoagulant responses to anthrax peptidoglycan are reinforced by proinflammatory cytokine signaling.
Narcis Ioan Popescu, Alanson Girton, +2 authors, K Mark Coggeshall.
Blood Adv, 2019 Aug 17; 3(16). PMID: 31416821    Free PMC article.
Therapeutic use of immunoglobulins.
E Richard Stiehm, Jordan S Orange, Mark Ballow, Heather Lehman.
Adv Pediatr, 2010 Nov 09; 57(1). PMID: 21056739    Free PMC article.
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Immunoreceptors on neutrophils.
Dieke J van Rees, Katka Szilagyi, +2 authors, Timo K van den Berg.
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Review.
The Role of Complement in Transfusion-Related Acute Lung Injury.
Ilse Jongerius, Leendert Porcelijn, +4 authors, Rick Kapur.
Transfus Med Rev, 2019 Nov 05; 33(4). PMID: 31676221    Free PMC article.
Review.
Impact of Human FcγR Gene Polymorphisms on IgG-Triggered Cytokine Release: Critical Importance of Cell Assay Format.
Khiyam Hussain, Chantal E Hargreaves, +9 authors, Mark S Cragg.
Front Immunol, 2019 Mar 23; 10. PMID: 30899264    Free PMC article.
Evaluation of in vitro Assays to Assess the Modulation of Dendritic Cells Functions by Therapeutic Antibodies and Aggregates.
Hannah Morgan, Su-Yi Tseng, +14 authors, Isabelle Turbica.
Front Immunol, 2019 Apr 20; 10. PMID: 31001248    Free PMC article.
PD-1 Primarily Targets TCR Signal in the Inhibition of Functional T Cell Activation.
Reina Mizuno, Daisuke Sugiura, +4 authors, Taku Okazaki.
Front Immunol, 2019 Apr 20; 10. PMID: 31001256    Free PMC article.
Exploring the Immunological Mechanisms Underlying the Anti-vascular Endothelial Growth Factor Activity in Tumors.
Rodrigo Barbosa de Aguiar, Jane Zveiter de Moraes.
Front Immunol, 2019 Jun 04; 10. PMID: 31156623    Free PMC article.
Review.
Antibody-Dependent Cellular Phagocytosis in Antiviral Immune Responses.
Matthew Zirui Tay, Kevin Wiehe, Justin Pollara.
Front Immunol, 2019 Mar 16; 10. PMID: 30873178    Free PMC article.
Review.
DecoyDeveloper: An On-Demand, De Novo Decoy Glycopeptide Generator.
Joshua T Shipman, Xiaomeng Su, David Hua, Heather Desaire.
J Proteome Res, 2019 May 28; 18(7). PMID: 31129958    Free PMC article.
The Human FcγRII (CD32) Family of Leukocyte FcR in Health and Disease.
Jessica C Anania, Alicia M Chenoweth, Bruce D Wines, P Mark Hogarth.
Front Immunol, 2019 Apr 04; 10. PMID: 30941127    Free PMC article.
Review.
An Engineered Human Fc variant With Exquisite Selectivity for FcγRIIIaV158 Reveals That Ligation of FcγRIIIa Mediates Potent Antibody Dependent Cellular Phagocytosis With GM-CSF-Differentiated Macrophages.
Tae Hyun Kang, Chang-Han Lee, +7 authors, George Georgiou.
Front Immunol, 2019 Apr 16; 10. PMID: 30984171    Free PMC article.
Current Concepts on 6-sulfo LacNAc Expressing Monocytes (slanMo).
Fareed Ahmad, Thomas Döbel, Marc Schmitz, Knut Schäkel.
Front Immunol, 2019 Jun 14; 10. PMID: 31191513    Free PMC article.
Review.
FcγR-Binding Is an Important Functional Attribute for Immune Checkpoint Antibodies in Cancer Immunotherapy.
Xin Chen, Xiaomin Song, Kang Li, Tong Zhang.
Front Immunol, 2019 Mar 14; 10. PMID: 30863404    Free PMC article.
Highly Cited. Review.
Molecular Insights Into the Relationship Between Autoimmune Thyroid Diseases and Breast Cancer: A Critical Perspective on Autoimmunity and ER Stress.
Safikur Rahman, Ayyagari Archana, +4 authors, Rinki Minakshi.
Front Immunol, 2019 Mar 19; 10. PMID: 30881358    Free PMC article.
Review.
Mind the Gap: How Interspecies Variability in IgG and Its Receptors May Complicate Comparisons of Human and Non-human Primate Effector Function.
Andrew R Crowley, Margaret E Ackerman.
Front Immunol, 2019 Apr 27; 10. PMID: 31024542    Free PMC article.
Review.
Chronic HIV-1 Infection Alters the Cellular Distribution of FcγRIIIa and the Functional Consequence of the FcγRIIIa-F158V Variant.
Ntando G Phaahla, Ria Lassaunière, +3 authors, Caroline T Tiemessen.
Front Immunol, 2019 Apr 27; 10. PMID: 31024562    Free PMC article.
FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming.
Willianne Hoepel, Melissa Newling, +6 authors, Jeroen den Dunnen.
Front Immunol, 2019 Apr 27; 10. PMID: 31024565    Free PMC article.
IgG and Fcγ Receptors in Intestinal Immunity and Inflammation.
Tomas Castro-Dopico, Menna R Clatworthy.
Front Immunol, 2019 Apr 30; 10. PMID: 31031776    Free PMC article.
Review.
Knowns and Unknowns of Assaying Antibody-Dependent Cell-Mediated Cytotoxicity Against HIV-1.
George K Lewis, Margaret E Ackerman, +7 authors, Bargavi Thyagarajan.
Front Immunol, 2019 May 28; 10. PMID: 31134085    Free PMC article.
Review.
Expression, Role, and Regulation of Neutrophil Fcγ Receptors.
Yu Wang, Friederike Jönsson.
Front Immunol, 2019 Sep 12; 10. PMID: 31507592    Free PMC article.
Review.
A Sample-Sparing Multiplexed ADCP Assay.
Audrey L Butler, Jonathan K Fallon, Galit Alter.
Front Immunol, 2019 Aug 29; 10. PMID: 31456799    Free PMC article.
Influenza and Antibody-Dependent Cellular Cytotoxicity.
Tarra A Von Holle, M Anthony Moody.
Front Immunol, 2019 Jul 19; 10. PMID: 31316510    Free PMC article.
Review.
Immunoglobulin Therapy in a Patient With Severe Chikungunya Fever and Vesiculobullous Lesions.
Ana Isabel V Fernandes, Joelma R Souza, +2 authors, Lúcio R C Castellano.
Front Immunol, 2019 Jul 18; 10. PMID: 31312203    Free PMC article.
How Autoantibodies Regulate Osteoclast Induced Bone Loss in Rheumatoid Arthritis.
Ulrike Steffen, Georg Schett, Aline Bozec.
Front Immunol, 2019 Jul 25; 10. PMID: 31333647    Free PMC article.
Review.
Targeting Conventional Dendritic Cells to Fine-Tune Antibody Responses.
Demo Yemane Tesfaye, Arnar Gudjonsson, Bjarne Bogen, Even Fossum.
Front Immunol, 2019 Jul 25; 10. PMID: 31333661    Free PMC article.
Review.
Alveolar Macrophage Dysfunction and Increased PD-1 Expression During Chronic SIV Infection of Rhesus Macaques.
Ruth Hunegnaw, Zuena Mushtaq, +2 authors, Marjorie Robert-Guroff.
Front Immunol, 2019 Jul 25; 10. PMID: 31333668    Free PMC article.
Influenza A Virus Antibodies with Antibody-Dependent Cellular Cytotoxicity Function.
Rongyuan Gao, Zizhang Sheng, +2 authors, Feng Li.
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Review.
Interaction analysis of glycoengineered antibodies with CD16a: a native mass spectrometry approach.
Joanna Hajduk, Cyrill Brunner, +5 authors, Renato Zenobi.
MAbs, 2020 Mar 14; 12(1). PMID: 32167012    Free PMC article.
Fc receptors in antibody-dependent enhancement of viral infections.
Adam Taylor, Suan-Sin Foo, +3 authors, Suresh Mahalingam.
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Review.
Kawasaki Disease: The Role of Immune Complexes Revisited.
Stephanie Menikou, Paul R Langford, Michael Levin.
Front Immunol, 2019 Jul 03; 10. PMID: 31263461    Free PMC article.
Review.
The Diverse Functions of the Ubiquitous Fcγ Receptors and Their Unique Constituent, FcRγ Subunit.
Thamer A Hamdan, Philipp A Lang, Karl S Lang.
Pathogens, 2020 Feb 26; 9(2). PMID: 32093173    Free PMC article.
Review.
Immunomodulation in Primary Immune Thrombocytopenia: A Possible Role of the Fc Fragment of Romiplostim?
Alexandra Schifferli, Falk Nimmerjahn, Thomas Kühne.
Front Immunol, 2019 Jun 20; 10. PMID: 31214173    Free PMC article.
Review.
Conceptual Approaches to Modulating Antibody Effector Functions and Circulation Half-Life.
Kevin O Saunders.
Front Immunol, 2019 Jun 25; 10. PMID: 31231397    Free PMC article.
Highly Cited. Review.
Lactoferrin-containing immunocomplex mediates antitumor effects by resetting tumor-associated macrophages to M1 phenotype.
Hongliang Dong, Yueyao Yang, +6 authors, Xiaoming Gao.
J Immunother Cancer, 2020 Mar 29; 8(1). PMID: 32217759    Free PMC article.
Reprogramming the Constant Region of Immunoglobulin G Subclasses for Enhanced Therapeutic Potency against Cancer.
Tae Hyun Kang, Sang Taek Jung.
Biomolecules, 2020 Mar 04; 10(3). PMID: 32121592    Free PMC article.
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A new cell line for assessing HIV-1 antibody dependent cellular cytotoxicity against a broad range of variants.
Allison S Thomas, Melissa Ghulam-Smith, +3 authors, Manish Sagar.
J Immunol Methods, 2020 Mar 07; 480. PMID: 32135162    Free PMC article.
Dual transcriptomic and epigenomic study of reaction severity in peanut-allergic children.
Anh N Do, Corey T Watson, +12 authors, Supinda Bunyavanich.
J Allergy Clin Immunol, 2019 Dec 16; 145(4). PMID: 31838046    Free PMC article.
The trinity of COVID-19: immunity, inflammation and intervention.
Matthew Zirui Tay, Chek Meng Poh, +2 authors, Lisa F P Ng.
Nat Rev Immunol, 2020 Apr 30; 20(6). PMID: 32346093    Free PMC article.
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Understanding SARS-CoV-2-Mediated Inflammatory Responses: From Mechanisms to Potential Therapeutic Tools.
Yajing Fu, Yuanxiong Cheng, Yuntao Wu.
Virol Sin, 2020 Mar 04; 35(3). PMID: 32125642    Free PMC article.
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Differential immunoglobulin and complement levels in leprosy prior to development of reversal reaction and erythema nodosum leprosum.
Francianne M Amorim, Maurício L Nobre, +11 authors, Selma M B Jeronimo.
PLoS Negl Trop Dis, 2019 Jan 29; 13(1). PMID: 30689631    Free PMC article.
A classical swine fever virus E2 fusion protein produced in plants elicits a neutralizing humoral immune response in mice and pigs.
Youngmin Park, Sangmin Lee, +8 authors, Eun-Ju Sohn.
Biotechnol Lett, 2020 Apr 24; 42(7). PMID: 32323080    Free PMC article.
Passive Immunotherapies for Central Nervous System Disorders: Current Delivery Challenges and New Approaches.
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Resistance Mechanisms Towards CD38-Directed Antibody Therapy in Multiple Myeloma.
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J Clin Med, 2020 Apr 26; 9(4). PMID: 32331242    Free PMC article.
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FcγR Binding and ADCC Activity of Human IgG Allotypes.
Steven W de Taeye, Arthur E H Bentlage, +10 authors, Gestur Vidarsson.
Front Immunol, 2020 May 22; 11. PMID: 32435243    Free PMC article.
Neuronal FcγRI mediates acute and chronic joint pain.
Li Wang, Xiaohua Jiang, +8 authors, Lintao Qu.
J Clin Invest, 2019 Jun 19; 129(9). PMID: 31211699    Free PMC article.
Isotype Switching Converts Anti-CD40 Antagonism to Agonism to Elicit Potent Antitumor Activity.
Xiaojie Yu, H T Claude Chan, +13 authors, Mark S Cragg.
Cancer Cell, 2020 May 23; 37(6). PMID: 32442402    Free PMC article.
HIV infection drives IgM and IgG3 subclass bias in Plasmodium falciparum-specific and total immunoglobulin concentration in Western Kenya.
Eliud O Odhiambo, Dibyadyuti Datta, +5 authors, Anne E P Frosch.
Malar J, 2019 Sep 01; 18(1). PMID: 31470903    Free PMC article.
CARs: Beyond T Cells and T Cell-Derived Signaling Domains.
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Int J Mol Sci, 2020 May 21; 21(10). PMID: 32429316    Free PMC article.
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Exploring pharmacological approaches for managing cytokine storm associated with pneumonia and acute respiratory distress syndrome in COVID-19 patients.
Irma Convertino, Marco Tuccori, +4 authors, Corrado Blandizzi.
Crit Care, 2020 Jun 13; 24(1). PMID: 32527304    Free PMC article.
A cross-reactive mouse monoclonal antibody against rhinovirus mediates phagocytosis in vitro.
Mohammad Amin Behzadi, Angela Choi, +5 authors, Raffael Nachbagauer.
Sci Rep, 2020 Jun 18; 10(1). PMID: 32546721    Free PMC article.
Looking for the Optimal PD-1/PD-L1 Inhibitor in Cancer Treatment: A Comparison in Basic Structure, Function, and Clinical Practice.
Yu Chen, Yanqing Pei, +3 authors, Xiangjiao Meng.
Front Immunol, 2020 Jun 18; 11. PMID: 32547566    Free PMC article.
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Opsonization-Enhanced Antigen Presentation by MR1 Activates Rapid Polyfunctional MAIT Cell Responses Acting as an Effector Arm of Humoral Antibacterial Immunity.
Caroline Boulouis, Jean-Baptiste Gorin, +3 authors, Johan K Sandberg.
J Immunol, 2020 May 22; 205(1). PMID: 32434941    Free PMC article.
Fc Gamma Receptors and Complement Component 3 Facilitate Anti-fVIII Antibody Formation.
Patricia E Zerra, Connie M Arthur, +11 authors, Sean R Stowell.
Front Immunol, 2020 Jun 26; 11. PMID: 32582142    Free PMC article.
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Front Immunol, 2020 Jul 01; 11. PMID: 32595635    Free PMC article.
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Signaling through the Inhibitory Fc Receptor FcγRIIB Induces CD8+ T Cell Apoptosis to Limit T Cell Immunity.
Anna B Morris, Clara R Farley, +8 authors, Mandy L Ford.
Immunity, 2020 Jan 16; 52(1). PMID: 31940267    Free PMC article.
Endoglycosidases for the Synthesis of Polysaccharides and Glycoconjugates.
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Adv Carbohydr Chem Biochem, 2016 Nov 07; 73. PMID: 27816108    Free PMC article.
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Differential Role for Activating FcγRIII in Neointima Formation After Arterial Injury and Diet-Induced Chronic Atherosclerosis in Apolipoprotein E-Deficient Mice.
Yaw Asare, Janine Koehncke, +6 authors, Erdenechimeg Shagdarsuren.
Front Physiol, 2020 Jul 07; 11. PMID: 32625118    Free PMC article.
The neonatal Fc receptor in cancer FcRn in cancer.
Diana Cadena Castaneda, Guillaume Brachet, +2 authors, Valérie Gouilleux-Gruart.
Cancer Med, 2020 May 06; 9(13). PMID: 32368865    Free PMC article.
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Spatiotemporal immune zonation of the human kidney.
Benjamin J Stewart, John R Ferdinand, +40 authors, Menna R Clatworthy.
Science, 2019 Oct 12; 365(6460). PMID: 31604275    Free PMC article.
Development of a VLP-Based Vaccine Displaying an xCT Extracellular Domain for the Treatment of Metastatic Breast Cancer.
Valeria Rolih, Jerri Caldeira, +12 authors, Federica Cavallo.
Cancers (Basel), 2020 Jun 12; 12(6). PMID: 32521631    Free PMC article.
Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis.
Chenzhi Jing, Tomas Castro-Dopico, +15 authors, Menna R Clatworthy.
Proc Natl Acad Sci U S A, 2020 Jun 17; 117(26). PMID: 32541026    Free PMC article.
Novel genetic variants in genes of the Fc gamma receptor-mediated phagocytosis pathway predict non-small cell lung cancer survival.
Danwen Qian, Hongliang Liu, +8 authors, Qingyi Wei.
Transl Lung Cancer Res, 2020 Jul 18; 9(3). PMID: 32676321    Free PMC article.
FcgRIII Deficiency and FcgRIIb Defeciency Promote Renal Injury in Diabetic Mice.
Rui Zhang, Tingli Wang, +13 authors, Fang Liu.
Biomed Res Int, 2019 Sep 20; 2019. PMID: 31534958    Free PMC article.
Role of Opsonophagocytosis in Immune Protection against Malaria.
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A single-cell atlas of the peripheral immune response in patients with severe COVID-19.
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Nat Med, 2020 Jun 10; 26(7). PMID: 32514174    Free PMC article.
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Sibel Kara, Lukas Amon, +3 authors, Anja Lux.
Front Immunol, 2020 Jul 28; 11. PMID: 32714325    Free PMC article.
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Fc Gamma Receptors and Their Role in Antigen Uptake, Presentation, and T Cell Activation.
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Front Immunol, 2020 Jul 29; 11. PMID: 32719679    Free PMC article.
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Memory T cell-mediated rejection is mitigated by FcγRIIB expression on CD8+ T cells.
Anna B Morris, David F Pinelli, +2 authors, Mandy L Ford.
Am J Transplant, 2020 Mar 11; 20(8). PMID: 32154641    Free PMC article.
A fentanyl vaccine constructed upon opsonizing antibodies specific for the Galα1-3Gal epitope.
Jiaxing Wang, Beverly Ellis, +3 authors, Kim D Janda.
Chem Commun (Camb), 2020 May 13; 56(48). PMID: 32396160    Free PMC article.
Neuroinflammation in dementia with Lewy bodies: a human post-mortem study.
Jay Amin, Clive Holmes, +6 authors, Delphine Boche.
Transl Psychiatry, 2020 Aug 05; 10(1). PMID: 32747635    Free PMC article.
Human Fcγ-receptor IIb modulates pathogen-specific versus self-reactive antibody responses in lyme arthritis.
Heike Danzer, Joachim Glaesner, +7 authors, Falk Nimmerjahn.
Elife, 2020 Jul 03; 9. PMID: 32613944    Free PMC article.
Sialylated Immunoglobulins for the Treatment of Immuno-Inflammatory Diseases.
Yuliya V Markina, Elena V Gerasimova, +4 authors, Alexander N Orekhov.
Int J Mol Sci, 2020 Aug 06; 21(15). PMID: 32751832    Free PMC article.
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Harnessing the Complete Repertoire of Conventional Dendritic Cell Functions for Cancer Immunotherapy.
Lukas Amon, Lukas Hatscher, +2 authors, Christian H K Lehmann.
Pharmaceutics, 2020 Jul 18; 12(7). PMID: 32674488    Free PMC article.
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Considerations of Antibody Geometric Constraints on NK Cell Antibody Dependent Cellular Cytotoxicity.
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Front Immunol, 2020 Aug 28; 11. PMID: 32849559    Free PMC article.
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Preferential Presentation of High-Affinity Immune Complexes in Germinal Centers Can Explain How Passive Immunization Improves the Humoral Response.
Amar K Garg, Rajat Desikan, Narendra M Dixit.
Cell Rep, 2019 Dec 19; 29(12). PMID: 31851925    Free PMC article.
A Plant-Derived Antigen-Antibody Complex Induces Anti-Cancer Immune Responses by Forming a Large Quaternary Structure.
Deuk-Su Kim, Yang Joo Kang, +5 authors, Kisung Ko.
Int J Mol Sci, 2020 Aug 09; 21(16). PMID: 32764343    Free PMC article.
Structural insights into the mechanisms and specificities of IgG-active endoglycosidases.
Jonathan J Du, Erik H Klontz, +2 authors, Eric J Sundberg.
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Targeting the blood-nerve barrier for the management of immune-mediated peripheral neuropathies.
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Exp Neurol, 2020 Jun 21; 331. PMID: 32562668    Free PMC article.
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The Role of IgG Subclass in Antibody-Mediated Protection against Carbapenem-Resistant Klebsiella pneumoniae.
Michael P Motley, Elizabeth Diago-Navarro, +2 authors, Bettina C Fries.
mBio, 2020 Sep 10; 11(5). PMID: 32900809    Free PMC article.
Beyond Allotypes: The Influence of Allelic Diversity in Antibody Constant Domains.
Annmaree K Warrender, William Kelton.
Front Immunol, 2020 Sep 26; 11. PMID: 32973808    Free PMC article.
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MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N-Glycosylation.
Thomas Sénard, Andrea F G Gargano, +6 authors, Elena Domínguez-Vega.
Front Immunol, 2020 Sep 26; 11. PMID: 32973813    Free PMC article.
Mechanisms of inside-out signaling of the high-affinity IgG receptor FcγRI.
Arianne M Brandsma, Samantha L Schwartz, +7 authors, Jeanette H W Leusen.
Sci Signal, 2018 Jul 26; 11(540). PMID: 30042128    Free PMC article.
Antibody immunoglobulin G1 and immunoglobulin G2a responses against some cystic fluid proteins of Cysticercus bovis in Balb/c mice.
I Nyoman Mantik Astawa, Ida Bagus Made Oka, I Made Dwinata.
Vet World, 2018 Dec 28; 11(11). PMID: 30587902    Free PMC article.
Heat-Killed Saccharomyces cerevisiae, A Dectin-1 Agonist, Selectively Induces IgG4 Production by Human B Cells.
Ha-Yan Park, Hee-Kyung Yoon, Jong-Yeup Kim, Seok-Rae Park.
Immune Netw, 2019 Jan 09; 18(6). PMID: 30619632    Free PMC article.
Epidermolysis Bullosa Acquisita: The 2019 Update.
Hiroshi Koga, Catherine Prost-Squarcioni, +3 authors, Katja Bieber.
Front Med (Lausanne), 2019 Jan 29; 5. PMID: 30687710    Free PMC article.
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Use of Dendritic Cell Receptors as Targets for Enhancing Anti-Cancer Immune Responses.
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Cancers (Basel), 2019 Mar 27; 11(3). PMID: 30909630    Free PMC article.
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Liposomal Fc Domain Conjugated to a Cancer Vaccine Enhances Both Humoral and Cellular Immunity.
Md Kamal Hossain, Abhishek Vartak, Steven J Sucheck, Katherine A Wall.
ACS Omega, 2019 Apr 06; 4(3). PMID: 30949616    Free PMC article.
Commentary: Fc Gamma Receptors are Expressed in the Developing Rat Brain and Activate Downstream Signaling Molecules upon Cross-Linking with Immune Complex.
Marianna Stamou, Pamela J Lein.
J Neurol Neuromedicine, 2019 May 28; 4(1). PMID: 31131371    Free PMC article.
Single-Domain Antibodies and Their Formatting to Combat Viral Infections.
Dorien De Vlieger, Marlies Ballegeer, +2 authors, Xavier Saelens.
Antibodies (Basel), 2019 Sep 24; 8(1). PMID: 31544807    Free PMC article.
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Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.
Susan H Tam, Stephen G McCarthy, +11 authors, Bernard J Scallon.
Antibodies (Basel), 2017 Sep 01; 6(3). PMID: 31548527    Free PMC article.
Neurological Complications Associated with the Blood-Brain Barrier Damage Induced by the Inflammatory Response During SARS-CoV-2 Infection.
Iván Alquisiras-Burgos, Irlanda Peralta-Arrieta, +3 authors, Penélope Aguilera.
Mol Neurobiol, 2020 Sep 27; 58(2). PMID: 32978729    Free PMC article.
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Stylianos Bournazos, Jeffrey V Ravetch.
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Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain.
Joschka Bauer, Sven Mathias, +6 authors, Anne R Karow-Zwick.
MAbs, 2020 Jul 14; 12(1). PMID: 32658605    Free PMC article.
Site-Specific Glycosylation Mapping of Fc Gamma Receptor IIIb from Neutrophils of Individual Healthy Donors.
Iwona Wojcik, Thomas Sénard, +7 authors, David Falck.
Anal Chem, 2020 Sep 05; 92(19). PMID: 32886488    Free PMC article.
Monoclonal Antibodies in Cancer Therapy.
David Zahavi, Louis Weiner.
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A versatile soluble siglec scaffold for sensitive and quantitative detection of glycan ligands.
Emily Rodrigues, Jaesoo Jung, +16 authors, Matthew S Macauley.
Nat Commun, 2020 Oct 11; 11(1). PMID: 33037195    Free PMC article.
SARS-CoV-2 mediated lung inflammatory responses in host: targeting the cytokine storm for therapeutic interventions.
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Mol Cell Biochem, 2020 Oct 17; 476(2). PMID: 33064288    Free PMC article.
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Kinase inhibition in autoimmunity and inflammation.
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Nat Rev Drug Discov, 2020 Oct 21; 20(1). PMID: 33077936    Free PMC article.
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Contributions of Major Cell Populations to Sjögren's Syndrome.
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J Clin Med, 2020 Sep 26; 9(9). PMID: 32971904    Free PMC article.
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Acquired antibody responses against merozoite surface protein-119 antigen during Plasmodium falciparum and P.vivax infections in South Indian city of Mangaluru.
Kishore Punnath, Kiran K Dayanand, +6 authors, D Channe Gowda.
J Parasit Dis, 2020 Oct 27; 45(1). PMID: 33100734    Free PMC article.
Aglycosylated antibody-producing mice for aglycosylated antibody-lectin coupled immunoassay for the quantification of tumor markers (ALIQUAT).
Nan-Ee Lee, Sun Hee Kim, +6 authors, Yong-Sam Kim.
Commun Biol, 2020 Nov 01; 3(1). PMID: 33128033    Free PMC article.
Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer's disease.
Garrett S Gibbons, Soo-Jung Kim, +10 authors, Virginia M Y Lee.
Mol Neurodegener, 2020 Nov 06; 15(1). PMID: 33148293    Free PMC article.
Intratumoral injection reduces toxicity and antibody-mediated neutralization of immunocytokine in a mouse melanoma model.
Claire C Baniel, Elizabeth G Sumiec, +8 authors, Paul M Sondel.
J Immunother Cancer, 2020 Oct 30; 8(2). PMID: 33115944    Free PMC article.
Role of Fcγ Receptor Mediated Inflammation in Immune Neuropathies.
Gang Zhang, Kazim A Sheikh.
J Clin Cell Immunol, 2017 Jan 01; 8(2). PMID: 33178482    Free PMC article.
Identification of "antigen-specific" neutrophils in atherosclerosis patients that compromise vascular endothelial barrier function.
Haisheng Chen, Liying Wu, +6 authors, Jiangping Song.
Am J Transl Res, 2020 Nov 17; 12(10). PMID: 33194075    Free PMC article.
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Biol Sex Differ, 2020 Nov 14; 11(1). PMID: 33183347    Free PMC article.
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Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality.
Tomer Zohar, Carolin Loos, +16 authors, Galit Alter.
Cell, 2020 Nov 19; 183(6). PMID: 33207184    Free PMC article.
RBD-Fc-based COVID-19 vaccine candidate induces highly potent SARS-CoV-2 neutralizing antibody response.
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Signal Transduct Target Ther, 2020 Nov 29; 5(1). PMID: 33247109    Free PMC article.
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Activation of Macrophages by Oligomeric Proteins of Different Size and Origin.
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Mediators Inflamm, 2018 Dec 26; 2018. PMID: 30581370    Free PMC article.
The Binding of Human IgG to Minipig FcγRs - Implications for Preclinical Assessment of Therapeutic Antibodies.
Jerome Egli, Tilman Schlothauer, +4 authors, Antonio Iglesias.
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Differences of the Structure of Immune Regulatory Cell Populations between Cellular Material from Sonographically Detected Focal Thyroid Lesions and Peripheral Blood in Humans.
Mariusz Stasiołek, Przemysław W Śliwka, +4 authors, Andrzej Lewiński.
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Impact of CD14 on Reactive Oxygen Species Production from Human Leukocytes Primed by Escherichia coli Lipopolysaccharides.
Dmitry S Kabanov, Olga Yu Vwedenskaya, +3 authors, Isabella R Prokhorenko.
Oxid Med Cell Longev, 2019 Apr 05; 2019. PMID: 30944694    Free PMC article.
Vaccination with a chikungunya virus-like particle vaccine exacerbates disease in aged mice.
Maria T Arévalo, Ying Huang, Cheryl A Jones, Ted M Ross.
PLoS Negl Trop Dis, 2019 Apr 27; 13(4). PMID: 31026260    Free PMC article.
Intercellular wireless communication network between mother and fetus in rat pregnancy-a study on directed and weighted network.
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Soluble fibrinogen-like protein 2 promotes the growth of hepatocellular carcinoma via attenuating dendritic cell-mediated cytotoxic T cell activity.
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Functional Interactions of Common Allotypes of Rhesus Macaque FcγR2A and FcγR3A with Human and Macaque IgG Subclasses.
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Fc-Engineering for Modulated Effector Functions-Improving Antibodies for Cancer Treatment.
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Functional Domain Order of an Anti-EGFR × Anti-CD16 Bispecific Diabody Involving NK Cell Activation.
Atsushi Kuwahara, Keisuke Nagai, +2 authors, Ryutaro Asano.
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Structure and dynamics of an α-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
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Nat Commun, 2020 Dec 06; 11(1). PMID: 33277506    Free PMC article.
Why remission is not enough: underlying disease mechanisms in RA that prevent cure.
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Nat Rev Rheumatol, 2020 Dec 12; 17(3). PMID: 33303993
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Engineered antibodies to combat viral threats.
Xiaojie Yu, Mark S Cragg.
Nature, 2020 Nov 20; 588(7838). PMID: 33208906
Environmental exposure enhances the internalization of microplastic particles into cells.
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Effects of estradiol on biological age measured using the glycan age index.
Julija Jurić, Wendy M Kohrt, +4 authors, Gordan Lauc.
Aging (Albany NY), 2020 Oct 14; 12(19). PMID: 33049709    Free PMC article.
An Anti-MICA/B Antibody and IL-15 Rescue Altered NKG2D-Dependent NK Cell Responses in Hepatocellular Carcinoma.
Stefania Mantovani, Stefania Varchetta, +19 authors, Barbara Oliviero.
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IgE and IgG Antibodies as Regulators of Mast Cell and Basophil Functions in Food Allergy.
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The Multiple Functions of B Cells in Chronic HBV Infection.
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TRIGGERED: could refocused cell signaling be key to natural killer cell-based HIV immunotherapeutics?
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The Current Landscape of Antibody-based Therapies in Solid Malignancies.
Ashu Shah, Sanchita Rauth, +6 authors, Surinder K Batra.
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COVID-19: inflammatory responses, structure-based drug design and potential therapeutics.
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FcγRIIb differentially regulates pre-immune and germinal center B cell tolerance in mouse and human.
Marion Espéli, Rachael Bashford-Rogers, +5 authors, Kenneth G C Smith.
Nat Commun, 2019 May 01; 10(1). PMID: 31036800    Free PMC article.
A quantitative Streptococcus pyogenes-human protein-protein interaction map reveals localization of opsonizing antibodies.
Lotta Happonen, Simon Hauri, +9 authors, Johan Malmström.
Nat Commun, 2019 Jun 23; 10(1). PMID: 31227708    Free PMC article.
Dysregulation of hepatic microRNA expression in C57BL/6 mice affected by excretory-secretory products of Fasciola gigantica.
Wei Shi, Jun-Jun He, +7 authors, Xing-Quan Zhu.
PLoS Negl Trop Dis, 2020 Dec 18; 14(12). PMID: 33332355    Free PMC article.
A proteomics-based method for identifying antigens within immune complexes.
Stephanie Menikou, Andrew J McArdle, +3 authors, Michael Levin.
PLoS One, 2020 Dec 29; 15(12). PMID: 33362259    Free PMC article.
A recombinant protein SARS-CoV-2 candidate vaccine elicits high-titer neutralizing antibodies in macaques.
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bioRxiv, 2021 Jan 06;. PMID: 33398285    Free PMC article.
Inhibition of B cell activation following in vivo co-engagement of B cell antigen receptor and Fcγ receptor IIb in non-autoimmune-prone and SLE-prone mice.
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J Transl Autoimmun, 2021 Jan 08; 4. PMID: 33409482    Free PMC article.
Gene Expression Analysis of the Pre-Diabetic Pancreas to Identify Pathogenic Mechanisms and Biomarkers of Type 1 Diabetes.
Linda Yip, Rebecca Fuhlbrigge, Reem Alkhataybeh, C Garrison Fathman.
Front Endocrinol (Lausanne), 2021 Jan 12; 11. PMID: 33424774    Free PMC article.
A Recombinant Protein SARS-CoV-2 Candidate Vaccine Elicits High-titer Neutralizing Antibodies in Macaques.
Gary Baisa, David Rancour, +9 authors, Kimberly Luke.
Res Sq, 2021 Jan 15;. PMID: 33442678    Free PMC article.
Therapeutic targeting of TGF-β in cancer: hacking a master switch of immune suppression.
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Intravenous Immunoglobulins at the Crossroad of Autoimmunity and Viral Infections.
Carlo Perricone, Paola Triggianese, +5 authors, Roberto Perricone.
Microorganisms, 2021 Jan 13; 9(1). PMID: 33430200    Free PMC article.
Review.
ADCC against MICA/B Is Mediated against Differentiated Oral and Pancreatic and Not Stem-Like/Poorly Differentiated Tumors by the NK Cells; Loss in Cancer Patients due to Down-Modulation of CD16 Receptor.
Kawaljit Kaur, Tahmineh Safaie, +2 authors, Anahid Jewett.
Cancers (Basel), 2021 Jan 15; 13(2). PMID: 33440654    Free PMC article.
Engineering Anti-Tumor Monoclonal Antibodies and Fc Receptors to Enhance ADCC by Human NK Cells.
Kate J Dixon, Jianming Wu, Bruce Walcheck.
Cancers (Basel), 2021 Jan 21; 13(2). PMID: 33467027    Free PMC article.
Review.
Efficacy of Margetuximab vs Trastuzumab in Patients With Pretreated ERBB2-Positive Advanced Breast Cancer: A Phase 3 Randomized Clinical Trial.
Hope S Rugo, Seock-Ah Im, +28 authors, SOPHIA Study Group.
JAMA Oncol, 2021 Jan 23; 7(4). PMID: 33480963    Free PMC article.
B Cell Aberrance in Lupus: the Ringleader and the Solution.
YuXue Nie, Lidan Zhao, Xuan Zhang.
Clin Rev Allergy Immunol, 2021 Feb 04; 62(2). PMID: 33534064
Review.
An Acquired and Endogenous Glycocalyx Forms a Bidirectional "Don't Eat" and "Don't Eat Me" Barrier to Phagocytosis.
Paul R C Imbert, Amra Saric, +3 authors, Spencer A Freeman.
Curr Biol, 2020 Oct 24; 31(1). PMID: 33096038    Free PMC article.
Understanding and Targeting Natural Killer Cell-Cancer-Associated Fibroblast Interactions in Pancreatic Ductal Adenocarcinoma.
Zoe X Malchiodi, Louis M Weiner.
Cancers (Basel), 2021 Jan 28; 13(3). PMID: 33499238    Free PMC article.
Review.
Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination.
Matthew J Gorman, Nita Patel, +28 authors, Galit Alter.
bioRxiv, 2021 Feb 11;. PMID: 33564763    Free PMC article.
Immunoglobulin G in Platelet-Derived Wound Healing Factors.
Elisa Seria, Sarah Samut Tagliaferro, +2 authors, Alex Felice.
Biomed Res Int, 2021 Feb 13; 2021. PMID: 33575328    Free PMC article.
IVIG ameliorate inflammation in collagen-induced arthritis: projection for IVIG therapy in rheumatoid arthritis.
G Halpert, I Katz, +8 authors, H Amital.
Clin Exp Immunol, 2020 Oct 07; 203(3). PMID: 33020923    Free PMC article.
Developing a 3D B Cell Lymphoma Culture System to Model Antibody Therapy.
Russell Foxall, Priyanka Narang, +6 authors, Mark S Cragg.
Front Immunol, 2021 Feb 26; 11. PMID: 33628205    Free PMC article.
A Strategy to Elicit M2e-Specific Antibodies Using a Recombinant H7N9 Live Attenuated Influenza Vaccine Expressing Multiple M2e Tandem Repeats.
Daria Mezhenskaya, Irina Isakova-Sivak, +6 authors, Larisa Rudenko.
Biomedicines, 2021 Feb 05; 9(2). PMID: 33535408    Free PMC article.
Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination.
Galit Alter, Matthew Gorman, +28 authors, Florian Krammer.
Res Sq, 2021 Feb 24;. PMID: 33619473    Free PMC article.
The Rheumatology Drugs for COVID-19 Management: Which and When?
Fabiola Atzeni, Ignazio Francesco Masala, +8 authors, Ricard Cervera.
J Clin Med, 2021 Mar 07; 10(4). PMID: 33669218    Free PMC article.
Review.
FcγRIIB is a T cell checkpoint in antitumor immunity.
Clara R Farley, Anna B Morris, +5 authors, Mandy L Ford.
JCI Insight, 2021 Feb 23; 6(4). PMID: 33616086    Free PMC article.
Engineered IgG1-Fc Molecules Define Valency Control of Cell Surface Fcγ Receptor Inhibition and Activation in Endosomes.
Elizabeth M Bailey, Amit Choudhury, +5 authors, Adam D Hoppe.
Front Immunol, 2021 Mar 09; 11. PMID: 33679705    Free PMC article.
Mesenchymal stem cell alongside exosomes as a novel cell-based therapy for COVID-19: A review study.
Meruyert Dauletova, Hafsan Hafsan, +3 authors, Homayoon Siahmansouri.
Clin Immunol, 2021 Mar 09; 226. PMID: 33684527    Free PMC article.
Review.
A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans.
Astrid Hagelkruys, Gerald Wirnsberger, +16 authors, Josef M Penninger.
J Exp Med, 2020 Sep 16; 218(1). PMID: 32930709    Free PMC article.
Next generation of anti-PD-L1 Atezolizumab with enhanced anti-tumor efficacy in vivo.
Maohua Li, Rongqing Zhao, +9 authors, Le Sun.
Sci Rep, 2021 Mar 13; 11(1). PMID: 33707569    Free PMC article.
Cellular and Humoral Immune Responses in Covid-19 and Immunotherapeutic Approaches.
Amal Hasan, Ebaa Al-Ozairi, +2 authors, Fahd Al-Mulla.
Immunotargets Ther, 2021 Mar 18; 10. PMID: 33728277    Free PMC article.
Review.
FcγRIIA expression accelerates nephritis and increases platelet activation in systemic lupus erythematosus.
Imene Melki, Isabelle Allaeys, +18 authors, Eric Boilard.
Blood, 2020 Dec 18; 136(25). PMID: 33331924    Free PMC article.
Identification of Reduced Host Transcriptomic Signatures for Tuberculosis Disease and Digital PCR-Based Validation and Quantification.
Harriet D Gliddon, Myrsini Kaforou, +18 authors, Michael Levin.
Front Immunol, 2021 Mar 26; 12. PMID: 33763081    Free PMC article.
Potential Target Genes in the Development of Atrial Fibrillation: A Comprehensive Bioinformatics Analysis.
Liang Liu, Yun Yu, +7 authors, Xiao-Shu Cheng.
Med Sci Monit, 2021 Mar 21; 27. PMID: 33741890    Free PMC article.
Human antiviral B cell responses: Emerging lessons from hepatitis B and COVID-19.
Alice R Burton, Mala K Maini.
Immunol Rev, 2021 Feb 10; 299(1). PMID: 33559128    Free PMC article.
Review.
Harnessing and Enhancing Macrophage Phagocytosis for Cancer Therapy.
Siqi Chen, Seigmund W T Lai, Christine E Brown, Mingye Feng.
Front Immunol, 2021 Apr 02; 12. PMID: 33790906    Free PMC article.
Review.
Germinal center reactions in tertiary lymphoid structures associate with neoantigen burden, humoral immunity and long-term survivorship in pancreatic cancer.
Andrew J Gunderson, Venkatesh Rajamanickam, +17 authors, Kristina H Young.
Oncoimmunology, 2021 Apr 03; 10(1). PMID: 33796412    Free PMC article.
Bruton's tyrosine kinase: an emerging targeted therapy in myeloid cells within the tumor microenvironment.
Logan Good, Brooke Benner, William E Carson.
Cancer Immunol Immunother, 2021 Apr 06; 70(9). PMID: 33818636    Free PMC article.
Review.
Immunological memory in rheumatic inflammation - a roadblock to tolerance induction.
Patrick Maschmeyer, Hyun-Dong Chang, +4 authors, Andreas Radbruch.
Nat Rev Rheumatol, 2021 Apr 08; 17(5). PMID: 33824526
Review.
The Advances and Challenges of NK Cell-Based Cancer Immunotherapy.
Synat Kang, Xuefeng Gao, +3 authors, Li Yu.
Curr Oncol, 2021 Mar 04; 28(2). PMID: 33652996    Free PMC article.
Review.
Spontaneous Breathing and Evolving Phenotypes of Lung Damage in Patients with COVID-19: Review of Current Evidence and Forecast of a New Scenario.
Roberto Tonelli, Alessandro Marchioni, +12 authors, Enrico Clini.
J Clin Med, 2021 Apr 04; 10(5). PMID: 33801368    Free PMC article.
Review.
Fcγ receptors on aging neutrophils.
Thaís Helena Gasparoto, Thalita Marcato Dalboni, +6 authors, Ana Paula Campanelli.
J Appl Oral Sci, 2021 Apr 08; 29. PMID: 33825754    Free PMC article.
C-Reactive Protein Suppresses the Th17 Response Indirectly by Attenuating the Antigen Presentation Ability of Monocyte Derived Dendritic Cells in Experimental Autoimmune Encephalomyelitis.
Zhi-Yuan Shen, Yi Zheng, +5 authors, Lin Zhang.
Front Immunol, 2021 Apr 13; 12. PMID: 33841391    Free PMC article.
NK Cell Adoptive Immunotherapy of Cancer: Evaluating Recognition Strategies and Overcoming Limitations.
Carlos E Sanchez, Ehsan P Dowlati, +4 authors, Conrad Russell Y Cruz.
Transplant Cell Ther, 2020 Oct 03; 27(1). PMID: 33007496