Review
. 2008 May; 133(5):775-87.
doi: 10.1016/j.cell.2008.05.009.

Regulatory T cells and immune tolerance

Shimon Sakaguchi 1 Tomoyuki Yamaguchi  Takashi Nomura  Masahiro Ono  
Affiliations
  • PMID: 18510923
  •     1946 citations

Abstract

Regulatory T cells (Tregs) play an indispensable role in maintaining immunological unresponsiveness to self-antigens and in suppressing excessive immune responses deleterious to the host. Tregs are produced in the thymus as a functionally mature subpopulation of T cells and can also be induced from naive T cells in the periphery. Recent research reveals the cellular and molecular basis of Treg development and function and implicates dysregulation of Tregs in immunological disease.

FOXP3 and its partners: structural and biochemical insights into the regulation of FOXP3 activity.
Zhaocai Zhou, Xiaomin Song, Bin Li, Mark I Greene.
Immunol Res, 2008 Jul 16; 42(1-3). PMID: 18626575
Review.
Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation.
Yasushi Onishi, Zoltan Fehervari, Tomoyuki Yamaguchi, Shimon Sakaguchi.
Proc Natl Acad Sci U S A, 2008 Jul 19; 105(29). PMID: 18635688    Free PMC article.
Highly Cited.
TGF-beta: a master of all T cell trades.
Ming O Li, Richard A Flavell.
Cell, 2008 Aug 12; 134(3). PMID: 18692464    Free PMC article.
Highly Cited. Review.
TGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3.
Arabinda Samanta, Bin Li, +8 authors, Mark I Greene.
Proc Natl Acad Sci U S A, 2008 Sep 10; 105(37). PMID: 18779564    Free PMC article.
Induction of immune tolerance by activation of CD8+ T suppressor/regulatory cells in lupus-prone mice.
Brian J Skaggs, Ram Pyare Singh, Bevra H Hahn.
Hum Immunol, 2008 Sep 27; 69(11). PMID: 18817829    Free PMC article.
Review.
Genetic engineering of T cells for adoptive immunotherapy.
Angel Varela-Rohena, Carmine Carpenito, +9 authors, James L Riley.
Immunol Res, 2008 Oct 09; 42(1-3). PMID: 18841331    Free PMC article.
Review.
Update in endocrine autoimmunity.
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J Clin Endocrinol Metab, 2008 Oct 10; 93(10). PMID: 18842982    Free PMC article.
Review.
Cytokine related therapies for autoimmune disease.
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Curr Opin Immunol, 2008 Oct 23; 20(6). PMID: 18940257    Free PMC article.
Review.
Mycobacterium bovis bacille Calmette-Guérin infection in the CNS suppresses experimental autoimmune encephalomyelitis and Th17 responses in an IFN-gamma-independent manner.
JangEun Lee, Emily K Reinke, +2 authors, Zsuzsanna Fabry.
J Immunol, 2008 Oct 23; 181(9). PMID: 18941210    Free PMC article.
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Curr Opin Immunol, 2008 Oct 29; 20(6). PMID: 18955138    Free PMC article.
Review.
Tumor necrosis factor-related apoptosis-inducing ligand inhibits experimental autoimmune thyroiditis by the expansion of CD4+CD25+ regulatory T cells.
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Endocrinology, 2008 Nov 15; 150(4). PMID: 19008314    Free PMC article.
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Nat Rev Immunol, 2008 Nov 15; 8(12). PMID: 19008897    Free PMC article.
Review.
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Immunol Cell Biol, 2008 Nov 26; 87(1). PMID: 19030016    Free PMC article.
Review.
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Immunity, 2008 Dec 09; 29(6). PMID: 19062319    Free PMC article.
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BMC Cancer, 2008 Dec 18; 8. PMID: 19087311    Free PMC article.
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Mol Ther, 2008 Dec 18; 17(2). PMID: 19088705    Free PMC article.
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Nat Rev Genet, 2008 Dec 19; 10(1). PMID: 19092835
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Review.
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Highly Cited.
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Diabetes, 2009 Jan 20; 58(4). PMID: 19151201    Free PMC article.
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Highly Cited.
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Clin Rev Allergy Immunol, 2009 Feb 03; 37(2). PMID: 19184559
Review.
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Highly Cited.
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Pediatr Nephrol, 2009 Feb 04; 24(6). PMID: 19189134
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Highly Cited.
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J Clin Immunol, 2009 Feb 28; 29(4). PMID: 19247822
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Proc Natl Acad Sci U S A, 2009 Mar 03; 106(12). PMID: 19251650    Free PMC article.
Comparative and developmental study of the immune system in Xenopus.
Jacques Robert, Yuko Ohta.
Dev Dyn, 2009 Mar 03; 238(6). PMID: 19253402    Free PMC article.
Review.
Development of AFFITOPE vaccines for Alzheimer's disease (AD)--from concept to clinical testing.
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J Nutr Health Aging, 2009 Mar 06; 13(3). PMID: 19262965
Review.
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Rahul Sharma, Sun-sang Joe Sung, Shu Man Fu, Shyr-Te Ju.
J Biomed Sci, 2009 Mar 11; 16. PMID: 19272184    Free PMC article.
Review.
An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance.
Weiming Ouyang, Omar Beckett, Richard A Flavell, Ming O Li.
Immunity, 2009 Mar 17; 30(3). PMID: 19285438    Free PMC article.
Highly Cited.
Dendritic cells as controllers of antigen-specific Foxp3+ regulatory T cells.
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J Dermatol Sci, 2009 Mar 17; 54(2). PMID: 19286352    Free PMC article.
Review.
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Review.
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Derese Getnet, Charles H Maris, +11 authors, Charles G Drake.
J Immunol, 2009 Apr 04; 182(8). PMID: 19342643    Free PMC article.
Treg versus Th17 lymphocyte lineages are cross-regulated by LIF versus IL-6.
Wenda Gao, Lorraine Thompson, +4 authors, Su M Metcalfe.
Cell Cycle, 2009 Apr 04; 8(9). PMID: 19342884    Free PMC article.
Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: immunopathogenesis and therapeutic implications.
Sébastien André, David F Tough, +2 authors, Jagadeesh Bayry.
Am J Pathol, 2009 Apr 08; 174(5). PMID: 19349365    Free PMC article.
Review.
Hepatic gene transfer as a means of tolerance induction to transgene products.
Paul A LoDuca, Brad E Hoffman, Roland W Herzog.
Curr Gene Ther, 2009 Apr 10; 9(2). PMID: 19355868    Free PMC article.
Review.
The companions: regulatory T cells and gene therapy.
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Immunology, 2009 Apr 17; 127(1). PMID: 19368560    Free PMC article.
Review.
Immunoregulatory functions of mTOR inhibition.
Angus W Thomson, Hēth R Turnquist, Giorgio Raimondi.
Nat Rev Immunol, 2009 Apr 25; 9(5). PMID: 19390566    Free PMC article.
Highly Cited. Review.
Parasite-dependent expansion of TNF receptor II-positive regulatory T cells with enhanced suppressive activity in adults with severe malaria.
Gabriela Minigo, Tonia Woodberry, +7 authors, Magdalena Plebanski.
PLoS Pathog, 2009 Apr 25; 5(4). PMID: 19390618    Free PMC article.
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation.
Meghan A Koch, Glady's Tucker-Heard, +3 authors, Daniel J Campbell.
Nat Immunol, 2009 May 05; 10(6). PMID: 19412181    Free PMC article.
Highly Cited.
Autoimmunity: CTLA-4: a key protein in autoimmunity.
Jagadeesh Bayry.
Nat Rev Rheumatol, 2009 May 05; 5(5). PMID: 19412189
OX40 engagement and chemotherapy combination provides potent antitumor immunity with concomitant regulatory T cell apoptosis.
Daniel Hirschhorn-Cymerman, Gabrielle A Rizzuto, +6 authors, Alan N Houghton.
J Exp Med, 2009 May 06; 206(5). PMID: 19414558    Free PMC article.
Sialoadhesin-positive macrophages bind regulatory T cells, negatively controlling their expansion and autoimmune disease progression.
Chuan Wu, Uwe Rauch, +4 authors, Lydia M Sorokin.
J Immunol, 2009 May 06; 182(10). PMID: 19414805    Free PMC article.
Tolerogenic dendritic cell-regulatory T-cell interaction and the promotion of transplant tolerance.
Angus W Thomson, Hēth R Turnquist, Alan F Zahorchak, Giorgio Raimondi.
Transplantation, 2009 May 14; 87(9 Suppl). PMID: 19424018    Free PMC article.
Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells.
Hélène Bour-Jordan, Jeffrey A Bluestone.
Immunol Rev, 2009 May 12; 229(1). PMID: 19426214    Free PMC article.
Review.
The significance of OX40 and OX40L to T-cell biology and immune disease.
Michael Croft, Takanori So, Wei Duan, Pejman Soroosh.
Immunol Rev, 2009 May 12; 229(1). PMID: 19426222    Free PMC article.
Highly Cited. Review.
Intraclonal competition limits the fate determination of regulatory T cells in the thymus.
Jhoanne L Bautista, Chan-Wang J Lio, +5 authors, Chyi-Song Hsieh.
Nat Immunol, 2009 May 12; 10(6). PMID: 19430476    Free PMC article.
Highly Cited.
Cyclophosphamide augments antitumor immunity: studies in an autochthonous prostate cancer model.
Satoshi Wada, Kiyoshi Yoshimura, +10 authors, Charles G Drake.
Cancer Res, 2009 May 14; 69(10). PMID: 19435909    Free PMC article.
Extracorporeal photopheresis-induced immune tolerance: a focus on modulation of antigen-presenting cells and induction of regulatory T cells by apoptotic cells.
Chang-Qing Xia, Kim A Campbell, Michael J Clare-Salzler.
Curr Opin Organ Transplant, 2009 May 16; 14(4). PMID: 19444106    Free PMC article.
Review.
Innate and adaptive immunity in atherosclerosis.
René R S Packard, Andrew H Lichtman, Peter Libby.
Semin Immunopathol, 2009 May 19; 31(1). PMID: 19449008    Free PMC article.
Review.
Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cells.
Joseph F Grosso, Monica V Goldberg, +7 authors, Charles G Drake.
J Immunol, 2009 May 21; 182(11). PMID: 19454660    Free PMC article.
CARMA1 controls an early checkpoint in the thymic development of FoxP3+ regulatory T cells.
Luciana L Molinero, Jianying Yang, +3 authors, Maria-Luisa Alegre.
J Immunol, 2009 May 21; 182(11). PMID: 19454668    Free PMC article.
Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells.
David J Chung, Marco Rossi, +4 authors, James W Young.
Blood, 2009 May 26; 114(3). PMID: 19465693    Free PMC article.
Highly Cited.
Monoclonal antibodies for podocytopathies: rationale and clinical responses.
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Nat Rev Nephrol, 2009 May 29; 5(6). PMID: 19474828
Review.
The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.
Guangwei Liu, Samir Burns, +4 authors, Hongbo Chi.
Nat Immunol, 2009 Jun 02; 10(7). PMID: 19483717    Free PMC article.
Highly Cited.
Fc receptor-like 3 protein expressed on IL-2 nonresponsive subset of human regulatory T cells.
Satoshi Nagata, Tomoko Ise, Ira Pastan.
J Immunol, 2009 Jun 06; 182(12). PMID: 19494275    Free PMC article.
Can childhood viral infection protect from type 1 diabetes?
Terry B Strom.
J Clin Invest, 2009 Jun 09; 119(6). PMID: 19504721    Free PMC article.
Heat shock protein 60 reactive T cells in juvenile idiopathic arthritis: what is new?
Yvonne Vercoulen, Nienke H van Teijlingen, +3 authors, Berent J Prakken.
Arthritis Res Ther, 2009 Jun 13; 11(3). PMID: 19519922    Free PMC article.
Review.
A novel modifier of regulatory T cells.
Naganari Ohkura, Shimon Sakaguchi.
Nat Immunol, 2009 Jun 19; 10(7). PMID: 19536192
Foxp3+ regulatory T cells: differentiation, specification, subphenotypes.
Markus Feuerer, Jonathan A Hill, Diane Mathis, Christophe Benoist.
Nat Immunol, 2009 Jun 19; 10(7). PMID: 19536194
Highly Cited. Review.
Peripheral induction of tolerance by retinal antigen expression.
Dale S Gregerson, Neal D Heuss, Ute Lehmann, Scott W McPherson.
J Immunol, 2009 Jun 23; 183(2). PMID: 19542366    Free PMC article.
Altered thymic selection and increased autoimmunity caused by ectopic expression of DRAK2 during T cell development.
Martina Gatzka, Ryan H Newton, Craig M Walsh.
J Immunol, 2009 Jun 23; 183(1). PMID: 19542440    Free PMC article.
New insights into the regulation of T cells by gamma(c) family cytokines.
Yrina Rochman, Rosanne Spolski, Warren J Leonard.
Nat Rev Immunol, 2009 Jun 23; 9(7). PMID: 19543225    Free PMC article.
Highly Cited. Review.
Absence of leucine zipper in the natural FOXP3Delta2Delta7 isoform does not affect dimerization but abrogates suppressive capacity.
Reiner K W Mailer, Kirsten Falk, Olaf Rötzschke.
PLoS One, 2009 Jul 02; 4(7). PMID: 19568423    Free PMC article.
Cytokine alteration and speculated immunological pathophysiology in silicosis and asbestos-related diseases.
Shuko Murakami, Yasumitsu Nishimura, +6 authors, Takemi Otsuki.
Environ Health Prev Med, 2009 Jul 02; 14(4). PMID: 19568841    Free PMC article.
Strategies to modulate immune responses: a new frontier for gene therapy.
Valder R Arruda, Patricia Favaro, Jonathan D Finn.
Mol Ther, 2009 Jul 09; 17(9). PMID: 19584819    Free PMC article.
Review.
Targeting lymphotoxin depletes pathogenic T cells.
Anna M Hansen, Rachel R Caspi.
Nat Med, 2009 Jul 09; 15(7). PMID: 19584860    Free PMC article.
The Nature of Increased Circulating CD4CD25Foxp3 T Cells in Patients with Systemic Lupus Erythematosus: A Novel Hypothesis.
Bing Yan, Yi Liu.
Open Rheumatol J, 2009 Jul 11; 3. PMID: 19590592    Free PMC article.
Th9 and allergic disease.
Pejman Soroosh, Taylor A Doherty.
Immunology, 2009 Jul 17; 127(4). PMID: 19604299    Free PMC article.
Review.
mTOR: taking cues from the immune microenvironment.
Greg M Delgoffe, Jonathan D Powell.
Immunology, 2009 Jul 17; 127(4). PMID: 19604300    Free PMC article.
Review.
Role of regulatory T cells in tolerance to coagulation factors.
O Cao, P A Loduca, R W Herzog.
J Thromb Haemost, 2009 Jul 28; 7 Suppl 1. PMID: 19630776    Free PMC article.
Review.
Vitamin D and immune function: understanding common pathways.
Daniel D Bikle.
Curr Osteoporos Rep, 2009 Jul 28; 7(2). PMID: 19631030
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters.
Markus Feuerer, Laura Herrero, +8 authors, Diane Mathis.
Nat Med, 2009 Jul 28; 15(8). PMID: 19633656    Free PMC article.
Highly Cited.
Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease.
Renat Shaykhiev, Anja Krause, +4 authors, Ronald G Crystal.
J Immunol, 2009 Jul 29; 183(4). PMID: 19635926    Free PMC article.
Highly Cited.
Down-modulation of programmed death 1 alters regulatory T cells and promotes experimental autoimmune encephalomyelitis.
Chunhe Wang, Yuexin Li, +2 authors, Halina Offner.
J Neurosci Res, 2009 Jul 31; 88(1). PMID: 19642196    Free PMC article.
Therapeutic manipulation of immune tolerance in allergic disease.
Mübeccel Akdis, Cezmi A Akdis.
Nat Rev Drug Discov, 2009 Aug 01; 8(8). PMID: 19644474
Review.
Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells.
Rui Wang, Lina Kozhaya, +3 authors, Derya Unutmaz.
Proc Natl Acad Sci U S A, 2009 Aug 12; 106(32). PMID: 19666573    Free PMC article.
Highly Cited.
Feedback control of regulatory T cell homeostasis by dendritic cells in vivo.
Guillaume Darrasse-Jèze, Stephanie Deroubaix, +8 authors, Michel C Nussenzweig.
J Exp Med, 2009 Aug 12; 206(9). PMID: 19667061    Free PMC article.
Highly Cited.
Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis.
Joost Smolders, Mariëlle Thewissen, +4 authors, Raymond Hupperts.
PLoS One, 2009 Aug 14; 4(8). PMID: 19675671    Free PMC article.
Betting on immunotherapy for melanoma.
Mario Sznol.
Curr Oncol Rep, 2009 Aug 15; 11(5). PMID: 19679015
Review.
Immature and maturation-resistant human dendritic cells generated from bone marrow require two stimulations to induce T cell anergy in vitro.
Thomas G Berger, Hendrik Schulze-Koops, +2 authors, Manfred B Lutz.
PLoS One, 2009 Aug 15; 4(8). PMID: 19680551    Free PMC article.
Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells.
Fan Pan, Hong Yu, +11 authors, Drew M Pardoll.
Science, 2009 Aug 22; 325(5944). PMID: 19696312    Free PMC article.
Highly Cited.
CD4+FOXP3+ regulatory T cells confer long-term regulation of factor VIII-specific immune responses in plasmid-mediated gene therapy-treated hemophilia mice.
Carol H Miao, Benjamin R Harmeling, +8 authors, David J Rawlings.
Blood, 2009 Aug 29; 114(19). PMID: 19713458    Free PMC article.
Extracellular redox modulation by regulatory T cells.
Zhonghua Yan, Sanjay K Garg, Jonathan Kipnis, Ruma Banerjee.
Nat Chem Biol, 2009 Sep 01; 5(10). PMID: 19718041    Free PMC article.
Enhancing the efficacy of cancer vaccines in urologic oncology: new directions.
Sergei Kusmartsev, Johannes Vieweg.
Nat Rev Urol, 2009 Sep 09; 6(10). PMID: 19736551
Review.
Mechanisms and clinical implications of glucocorticosteroids in the treatment of allergic rhinitis.
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Clin Exp Immunol, 2009 Sep 10; 158(2). PMID: 19737138    Free PMC article.
Review.
TCR-dependent differentiation of thymic Foxp3+ cells is limited to small clonal sizes.
Monica W L Leung, Shiqian Shen, Juan J Lafaille.
J Exp Med, 2009 Sep 10; 206(10). PMID: 19737865    Free PMC article.
Regulatory T cells and immune tolerance to tumors.
Xuefang Cao.
Immunol Res, 2009 Sep 19; 46(1-3). PMID: 19763889
Review.
Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells.
Dipayan Rudra, Takeshi Egawa, +3 authors, Alexander Y Rudensky.
Nat Immunol, 2009 Sep 22; 10(11). PMID: 19767756    Free PMC article.
CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury.
Franco R D'Alessio, Kenji Tsushima, +8 authors, Landon S King.
J Clin Invest, 2009 Sep 23; 119(10). PMID: 19770521    Free PMC article.
Highly Cited.
Depletion of CD4+CD25+ regulatory T cells enhances natural killer T cell-mediated anti-tumour immunity in a murine mammary breast cancer model.
H Hong, Y Gu, +5 authors, S Jiang.
Clin Exp Immunol, 2009 Oct 13; 159(1). PMID: 19817769    Free PMC article.
How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets.
Markus Feuerer, Yuelei Shen, +2 authors, Diane Mathis.
Immunity, 2009 Oct 13; 31(4). PMID: 19818653    Free PMC article.
Highly Cited.
Mechanistic insights into immunomodulation by hepatic stellate cells in mice: a critical role of interferon-gamma signaling.
Horng-Ren Yang, Hong-Shuie Chou, +5 authors, Shiguang Qian.
Hepatology, 2009 Oct 13; 50(6). PMID: 19821484    Free PMC article.
Autoimmune thyroiditis: a model uniquely suited to probe regulatory T cell function.
Yi-Chi M Kong, Gerald P Morris, +3 authors, Chella S David.
J Autoimmun, 2009 Oct 14; 33(3-4). PMID: 19822405    Free PMC article.
Review.
The gut feeling of Treg cells: IL-10 is the silver lining during colitis.
Derya Unutmaz, Bali Pulendran.
Nat Immunol, 2009 Oct 21; 10(11). PMID: 19841645
Targeting a mimotope vaccine to activating Fcgamma receptors empowers dendritic cells to prime specific CD8+ T cell responses in tumor-bearing mice.
Margaret Gil, Magdalena Bieniasz, +3 authors, Danuta Kozbor.
J Immunol, 2009 Oct 23; 183(10). PMID: 19846865    Free PMC article.
Forkhead transcription factors in chronic inflammation.
Stanford L Peng.
Int J Biochem Cell Biol, 2009 Oct 24; 42(4). PMID: 19850149    Free PMC article.
Review.
Dual mechanism of impairment of interleukin-7 (IL-7) responses in human immunodeficiency virus infection: decreased IL-7 binding and abnormal activation of the JAK/STAT5 pathway.
Olivier Juffroy, Florence Bugault, +7 authors, Lisa A Chakrabarti.
J Virol, 2009 Oct 30; 84(1). PMID: 19864382    Free PMC article.
IFN-gamma triggered STAT1-PKB/AKT signalling pathway influences the function of alloantigen reactive regulatory T cells.
B Wei, S Baker, J Wieckiewicz, K J Wood.
Am J Transplant, 2009 Nov 06; 10(1). PMID: 19889125    Free PMC article.
The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis.
E C Lavelle, C Murphy, L A J O'Neill, E M Creagh.
Mucosal Immunol, 2009 Nov 06; 3(1). PMID: 19890268    Free PMC article.
Review.
Rhesus monkey immature monocyte-derived dendritic cells generate alloantigen-specific regulatory T cells from circulating CD4+CD127-/lo T cells.
Alan F Zahorchak, Giorgio Raimondi, Angus W Thomson.
Transplantation, 2009 Nov 10; 88(9). PMID: 19898200    Free PMC article.
Unaltered negative selection and Treg development of self-reactive thymocytes in TCR transgenic Fyn-deficient mice.
Alusha A Mamchak, Christine B F Thien, +4 authors, Anthony L DeFranco.
Eur J Immunol, 2009 Nov 12; 40(2). PMID: 19904769    Free PMC article.
Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells.
Sven Klunker, Mark M W Chong, +8 authors, Cezmi A Akdis.
J Exp Med, 2009 Nov 18; 206(12). PMID: 19917773    Free PMC article.
Induction of antigen-specific immune tolerance by TGF-beta-induced CD4+Foxp3+ regulatory T cells.
Huimin Fan, Julie Wang, +2 authors, Song Guo Zheng.
Int J Clin Exp Med, 2009 Nov 18; 2(3). PMID: 19918314    Free PMC article.
Immune tolerance induction by integrating innate and adaptive immune regulators.
Jun Suzuki, Camillo Ricordi, Zhibin Chen.
Cell Transplant, 2009 Nov 19; 19(3). PMID: 19919733    Free PMC article.
Review.
Targeting the tumor microenvironment with anti-neu/anti-CD40 conjugated nanoparticles for the induction of antitumor immune responses.
Ana Lucia Dominguez, Joseph Lustgarten.
Vaccine, 2009 Nov 26; 28(5). PMID: 19931385    Free PMC article.
Antigen-specific dependence of Tr1-cell therapy in preclinical models of islet transplant.
Nicola Gagliani, Tatiana Jofra, +4 authors, Manuela Battaglia.
Diabetes, 2009 Nov 26; 59(2). PMID: 19934002    Free PMC article.
Synergistic effect of TGF-beta superfamily members on the induction of Foxp3+ Treg.
Ling Lu, Jilin Ma, +9 authors, Song Guo Zheng.
Eur J Immunol, 2009 Nov 28; 40(1). PMID: 19943263    Free PMC article.
Generalized immune activation as a direct result of activated CD4+ T cell killing.
Rute Marques, Adam Williams, +5 authors, George Kassiotis.
J Biol, 2009 Dec 01; 8(10). PMID: 19943952    Free PMC article.
CD4(+)CD25(+) regulatory T cells resist a novel form of CD28- and Fas-dependent p53-induced T cell apoptosis.
Nagendra Singh, Mutsumi Yamamoto, +4 authors, Makio Iwashima.
J Immunol, 2009 Dec 02; 184(1). PMID: 19949106    Free PMC article.
Functional anatomy of T cell activation and synapse formation.
David R Fooksman, Santosh Vardhana, +7 authors, Michael L Dustin.
Annu Rev Immunol, 2009 Dec 09; 28. PMID: 19968559    Free PMC article.
Highly Cited. Review.
Mammalian target of rapamycin inhibition and alloantigen-specific regulatory T cells synergize to promote long-term graft survival in immunocompetent recipients.
Giorgio Raimondi, Tina L Sumpter, +5 authors, Angus W Thomson.
J Immunol, 2009 Dec 17; 184(2). PMID: 20007530    Free PMC article.
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells.
Loise M Francisco, Victor H Salinas, +4 authors, Arlene H Sharpe.
J Exp Med, 2009 Dec 17; 206(13). PMID: 20008522    Free PMC article.
Highly Cited.
Emergent group dynamics governed by regulatory cells produce a robust primary T cell response.
Peter S Kim, Peter P Lee, Doron Levy.
Bull Math Biol, 2009 Dec 17; 72(3). PMID: 20013355    Free PMC article.
Regulatory T cells exert checks and balances on self tolerance and autoimmunity.
Kajsa Wing, Shimon Sakaguchi.
Nat Immunol, 2009 Dec 18; 11(1). PMID: 20016504
Highly Cited. Review.
FoxP3+ regulatory T cells essentially contribute to peripheral CD8+ T-cell tolerance induced by steady-state dendritic cells.
Anita Schildknecht, Sabine Brauer, +5 authors, Maries van den Broek.
Proc Natl Acad Sci U S A, 2009 Dec 19; 107(1). PMID: 20018763    Free PMC article.
Reduction of Foxp3+ cells by depletion with the PC61 mAb induces mortality in resistant BALB/c mice infected with Toxoplasma gondii.
Eda Patricia Tenorio, Jonadab Efraín Olguín, +2 authors, Rafael Saavedra.
J Biomed Biotechnol, 2009 Dec 29; 2010. PMID: 20037737    Free PMC article.
In vivo dynamical interactions between CD4 Tregs, CD8 Tregs and CD4+ CD25- cells in mice.
Arnon Arazi, Amir Sharabi, +2 authors, Avidan U Neumann.
PLoS One, 2009 Dec 31; 4(12). PMID: 20041142    Free PMC article.
Vitiligo vulgaris and autoimmune diseases in Japan: A report from vitiligo clinic in Kyoto University Hospital.
Miki Tanioka, Yosuke Yamamoto, +2 authors, Yoshiki Miyachi.
Dermatoendocrinol, 2010 Jan 05; 1(1). PMID: 20046588    Free PMC article.
In situ patrolling of regulatory T cells is essential for protecting autoimmune exocrinopathy.
Naozumi Ishimaru, Takeshi Nitta, +4 authors, Yoshio Hayashi.
PLoS One, 2010 Jan 07; 5(1). PMID: 20052419    Free PMC article.
Fluorosomes: a convenient new reagent to detect and block multivalent and complex receptor-ligand interactions.
Hans J Kueng, Calin Manta, +8 authors, Winfried F Pickl.
FASEB J, 2010 Jan 09; 24(5). PMID: 20056716    Free PMC article.
Costimulator B7-DC attenuates strong Th2 responses induced by Nippostrongylus brasiliensis.
Kenji Ishiwata, Naohiro Watanabe, +6 authors, Tahiro Shin.
J Immunol, 2010 Jan 13; 184(4). PMID: 20065112    Free PMC article.
Expression and function of TNF and IL-1 receptors on human regulatory T cells.
Frances Mercer, Lina Kozhaya, Derya Unutmaz.
PLoS One, 2010 Jan 13; 5(1). PMID: 20066156    Free PMC article.
Redox remodeling as an immunoregulatory strategy.
Zhonghua Yan, Ruma Banerjee.
Biochemistry, 2010 Jan 15; 49(6). PMID: 20070126    Free PMC article.
Review.
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate.
Ye Zheng, Steven Josefowicz, +3 authors, Alexander Y Rudensky.
Nature, 2010 Jan 15; 463(7282). PMID: 20072126    Free PMC article.
Highly Cited.
High-dose RHAMM-R3 peptide vaccination for patients with acute myeloid leukemia, myelodysplastic syndrome and multiple myeloma.
Jochen Greiner, Anita Schmitt, +9 authors, Michael Schmitt.
Haematologica, 2010 Jan 19; 95(7). PMID: 20081055    Free PMC article.
CD40-activated B cells are more potent than immature dendritic cells to induce and expand CD4(+) regulatory T cells.
Jian Zheng, Yinping Liu, Yu-Lung Lau, Wenwei Tu.
Cell Mol Immunol, 2010 Jan 19; 7(1). PMID: 20081875    Free PMC article.
Development, regulation and functional capacities of Th17 cells.
Keiji Hirota, Bruno Martin, Marc Veldhoen.
Semin Immunopathol, 2010 Jan 29; 32(1). PMID: 20107806
Review.
Foxp3 positive regulatory T cells: a functional regulation by the E3 ubiquitin ligase Itch.
Jin Su, Yun-Cai Liu.
Semin Immunopathol, 2010 Jan 29; 32(2). PMID: 20108139    Free PMC article.
Review.
Mast cells mobilize myeloid-derived suppressor cells and Treg cells in tumor microenvironment via IL-17 pathway in murine hepatocarcinoma model.
Zhuoshun Yang, Biao Zhang, +4 authors, Bo Huang.
PLoS One, 2010 Jan 30; 5(1). PMID: 20111717    Free PMC article.
The contribution of Asian researchers to the field of rheumatology.
Yoshihisa Yamano, Kusuki Nishioka.
Nat Rev Rheumatol, 2010 Feb 04; 6(2). PMID: 20125178
Review.
Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments.
Dorothea Busse, Maurus de la Rosa, +4 authors, Thomas Höfer.
Proc Natl Acad Sci U S A, 2010 Feb 06; 107(7). PMID: 20133667    Free PMC article.
Increased levels of Treg cells in bronchoalveolar lavage fluid and induced sputum of patients with active pulmonary sarcoidosis.
R M Mroz, M Korniluk, +2 authors, E Chyczewska.
Eur J Med Res, 2010 Jul 14; 14 Suppl 4. PMID: 20156750    Free PMC article.
Regulatory T cells in many flavors control asthma.
A Ray, A Khare, +2 authors, P Ray.
Mucosal Immunol, 2010 Feb 19; 3(3). PMID: 20164832    Free PMC article.
Review.
Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice.
Michio Tomura, Tetsuya Honda, +10 authors, Kenji Kabashima.
J Clin Invest, 2010 Feb 25; 120(3). PMID: 20179354    Free PMC article.
Highly Cited.
Cancer vaccine by fusions of dendritic and cancer cells.
Shigeo Koido, Eiichi Hara, +4 authors, Hisao Tajiri.
Clin Dev Immunol, 2010 Feb 26; 2009. PMID: 20182533    Free PMC article.
Review.
Mediators of inflammation in acute kidney injury.
Ali Akcay, Quocan Nguyen, Charles L Edelstein.
Mediators Inflamm, 2010 Feb 26; 2009. PMID: 20182538    Free PMC article.
Highly Cited. Review.
Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells.
John J O'Shea, William E Paul.
Science, 2010 Feb 27; 327(5969). PMID: 20185720    Free PMC article.
Highly Cited. Review.
CD122+CD8+ Treg suppress vaccine-induced antitumor immune responses in lymphodepleted mice.
Li-Xin Wang, Yuhuan Li, +5 authors, Hong-Ming Hu.
Eur J Immunol, 2010 Feb 27; 40(5). PMID: 20186876    Free PMC article.
Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of programmed cell death-1.
Louise A Swainson, Jeff E Mold, Urmila D Bajpai, Joseph M McCune.
J Immunol, 2010 Mar 02; 184(7). PMID: 20190142    Free PMC article.
Measles virus-induced immunosuppression in SLAM knock-in mice.
Ritsuko Koga, Shinji Ohno, Satoshi Ikegame, Yusuke Yanagi.
J Virol, 2010 Mar 05; 84(10). PMID: 20200244    Free PMC article.
Cell-based immunotherapy with mesenchymal stem cells cures bisphosphonate-related osteonecrosis of the jaw-like disease in mice.
Takashi Kikuiri, Insoo Kim, +8 authors, Songtao Shi.
J Bone Miner Res, 2010 Mar 05; 25(7). PMID: 20200952    Free PMC article.
Norwalk virus-like particles as vaccines.
Melissa Herbst-Kralovetz, Hugh S Mason, Qiang Chen.
Expert Rev Vaccines, 2010 Mar 12; 9(3). PMID: 20218858    Free PMC article.
Review.
Adaptive autoimmunity and Foxp3-based immunoregulation in zebrafish.
Francisco J Quintana, Antonio H Iglesias, +5 authors, Howard L Weiner.
PLoS One, 2010 Mar 12; 5(3). PMID: 20221429    Free PMC article.
Genomic definition of multiple ex vivo regulatory T cell subphenotypes.
Markus Feuerer, Jonathan A Hill, +3 authors, Christophe Benoist.
Proc Natl Acad Sci U S A, 2010 Mar 17; 107(13). PMID: 20231436    Free PMC article.
Highly Cited.
Dendritic cells control T cell tonic signaling required for responsiveness to foreign antigen.
Kristin Hochweller, Guido H Wabnitz, +3 authors, Natalio Garbi.
Proc Natl Acad Sci U S A, 2010 Mar 17; 107(13). PMID: 20231464    Free PMC article.
CARMA1 regulation of regulatory T cell development involves modulation of interleukin-2 receptor signaling.
Andrew Joon Lee, Xuefeng Wu, +3 authors, Shao-Cong Sun.
J Biol Chem, 2010 Mar 18; 285(21). PMID: 20233721    Free PMC article.
Mycobacteria-induced suppression of autoimmunity in the central nervous system.
JangEun Lee, Matyas Sandor, Erika Heninger, Zsuzsanna Fabry.
J Neuroimmune Pharmacol, 2010 Mar 25; 5(2). PMID: 20333556    Free PMC article.
Review.
Regulation of the T helper cell type 2 (Th2)/T regulatory cell (Treg) balance by IL-4 and STAT6.
Svetlana Chapoval, Preeta Dasgupta, Nicolas J Dorsey, Achsah D Keegan.
J Leukoc Biol, 2010 Mar 26; 87(6). PMID: 20335310    Free PMC article.
Review.
Protein kinase C-theta mediates negative feedback on regulatory T cell function.
Alexandra Zanin-Zhorov, Yi Ding, +7 authors, Michael L Dustin.
Science, 2010 Mar 27; 328(5976). PMID: 20339032    Free PMC article.
Highly Cited.
Cutting edge: human latency-associated peptide+ T cells: a novel regulatory T cell subset.
Roopali Gandhi, Mauricio F Farez, +3 authors, Howard L Weiner.
J Immunol, 2010 Apr 07; 184(9). PMID: 20368276    Free PMC article.
OX40 is required for regulatory T cell-mediated control of colitis.
Thibault Griseri, Mark Asquith, Claire Thompson, Fiona Powrie.
J Exp Med, 2010 Apr 07; 207(4). PMID: 20368580    Free PMC article.
CD8+ Tregs in lupus, autoimmunity, and beyond.
Ravi K Dinesh, Brian J Skaggs, +2 authors, Ram Pyare Singh.
Autoimmun Rev, 2010 Apr 14; 9(8). PMID: 20385256    Free PMC article.
Review.
Hypoxia-driven immunosuppression: a new reason to use thermal therapy in the treatment of cancer?
Chen-Ting Lee, Thomas Mace, Elizabeth A Repasky.
Int J Hyperthermia, 2010 Apr 15; 26(3). PMID: 20388021    Free PMC article.
Review.
Altered regulatory T cell homeostasis in patients with CD4+ lymphopenia following allogeneic hematopoietic stem cell transplantation.
Ken-ichi Matsuoka, Haesook T Kim, +9 authors, Jerome Ritz.
J Clin Invest, 2010 Apr 15; 120(5). PMID: 20389017    Free PMC article.
Highly Cited.
Cbl-b and itch: key regulators of peripheral T-cell tolerance.
K Venuprasad.
Cancer Res, 2010 Apr 17; 70(8). PMID: 20395198    Free PMC article.
Review.
Immunomodulation by intravenous immunoglobulin: role of regulatory T cells.
Mohan S Maddur, Shivashankar Othy, +4 authors, Srini V Kaveri.
J Clin Immunol, 2010 Apr 21; 30 Suppl 1. PMID: 20405183
Review.
Autoimmune polyendocrine syndromes: clues to type 1 diabetes pathogenesis.
Eystein S Husebye, Mark S Anderson.
Immunity, 2010 Apr 24; 32(4). PMID: 20412758    Free PMC article.
Review.
CD28 facilitates the generation of Foxp3(-) cytokine responsive regulatory T cell precursors.
Chan-Wang J Lio, Lindzy F Dodson, +2 authors, Jonathan M Green.
J Immunol, 2010 Apr 28; 184(11). PMID: 20421644    Free PMC article.
Anti-CD154 mAb and rapamycin induce T regulatory cell mediated tolerance in rat-to-mouse islet transplantation.
Yannick D Muller, Gang Mai, +12 authors, Leo H Bühler.
PLoS One, 2010 May 04; 5(4). PMID: 20436684    Free PMC article.
Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells.
Yohsuke Harada, Yasuyo Harada, +4 authors, Yun-Cai Liu.
J Exp Med, 2010 May 05; 207(7). PMID: 20439537    Free PMC article.
Highly Cited.
Thymic changes after chorioamnionitis induced by intraamniotic lipopolysaccharide in fetal sheep.
Steffen Kunzmann, Kerstin Glogger, +7 authors, Boris W Kramer.
Am J Obstet Gynecol, 2010 May 11; 202(5). PMID: 20452494    Free PMC article.
Induction of transplantation tolerance to fully mismatched cardiac allografts by T cell mediated delivery of alloantigen.
Chaorui Tian, Xueli Yuan, +3 authors, John Iacomini.
Clin Immunol, 2010 May 11; 136(2). PMID: 20452826    Free PMC article.
HIV-1 impairs in vitro priming of naïve T cells and gives rise to contact-dependent suppressor T cells.
Karlhans F Che, Rachel L Sabado, +5 authors, Marie Larsson.
Eur J Immunol, 2010 May 11; 40(8). PMID: 20455275    Free PMC article.
Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells.
Weiming Ouyang, Omar Beckett, +3 authors, Ming O Li.
Nat Immunol, 2010 May 15; 11(7). PMID: 20467422
Highly Cited.
Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development.
Weiming Ouyang, Omar Beckett, Qian Ma, Ming O Li.
Immunity, 2010 May 18; 32(5). PMID: 20471291    Free PMC article.
Highly Cited.
Enhanced suppressive function of regulatory T cells from patients with immune-mediated diseases following successful ex vivo expansion.
Tinghua Cao, Sally E Wenzel, +2 authors, Li Li.
Clin Immunol, 2010 May 18; 136(3). PMID: 20472506    Free PMC article.
Diversity of TCRs on natural Foxp3+ T cells in mice lacking Aire expression.
Danielle Daniely, Joanna Kern, Anna Cebula, Leszek Ignatowicz.
J Immunol, 2010 May 21; 184(12). PMID: 20483761    Free PMC article.
Investigating the induction of vaccine-induced Th17 and regulatory T cells in healthy, Mycobacterium bovis BCG-immunized adults vaccinated with a new tuberculosis vaccine, MVA85A.
Simone C de Cassan, Ansar A Pathan, +5 authors, Helen A Fletcher.
Clin Vaccine Immunol, 2010 May 21; 17(7). PMID: 20484570    Free PMC article.
Natural Foxp3(+) regulatory T cells inhibit Th2 polarization but are biased toward suppression of Th17-driven lung inflammation.
Teri Girtsman, Zeina Jaffar, +2 authors, Kevan Roberts.
J Leukoc Biol, 2010 May 25; 88(3). PMID: 20495073    Free PMC article.
Why functional pre-erythrocytic and bloodstage malaria vaccines fail: a meta-analysis of fully protective immunizations and novel immunological model.
D Lys Guilbride, Pawel Gawlinski, Patrick D L Guilbride.
PLoS One, 2010 May 27; 5(5). PMID: 20502667    Free PMC article.
T regulatory cells and transplantation tolerance.
Vijay S Gorantla, Stefan Schneeberger, +4 authors, Xin Xiao Zheng.
Transplant Rev (Orlando), 2010 Jun 15; 24(3). PMID: 20541385    Free PMC article.
Review.
Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis.
Shahin Shafiani, Glady's Tucker-Heard, +2 authors, Kevin B Urdahl.
J Exp Med, 2010 Jun 16; 207(7). PMID: 20547826    Free PMC article.
Highly Cited.
Crosstalk between decidual NK and CD14+ myelomonocytic cells results in induction of Tregs and immunosuppression.
Paola Vacca, Claudia Cantoni, +6 authors, Maria Cristina Mingari.
Proc Natl Acad Sci U S A, 2010 Jun 16; 107(26). PMID: 20547831    Free PMC article.
FOXP3+ regulatory T cells in the human immune system.
Shimon Sakaguchi, Makoto Miyara, Cristina M Costantino, David A Hafler.
Nat Rev Immunol, 2010 Jun 19; 10(7). PMID: 20559327
Highly Cited. Review.
PI3Ks in lymphocyte signaling and development.
Klaus Okkenhaug, David A Fruman.
Curr Top Microbiol Immunol, 2010 Jun 22; 346. PMID: 20563708    Free PMC article.
Review.
Control of Th2-mediated inflammation by regulatory T cells.
K Venuprasad, K Venuprasad Poojary, Yi-Chi M Kong, Michael A Farrar.
Am J Pathol, 2010 Jun 23; 177(2). PMID: 20566752    Free PMC article.
Review.
The relationship of x-linked primary immune deficiencies and autoimmunity.
Itai M Pessach.
Curr Allergy Asthma Rep, 2010 Jun 24; 10(5). PMID: 20571932
Review.
Altered effector CD4+ T cell function in IL-21R-/- CD4+ T cell-mediated graft-versus-host disease.
Iekuni Oh, Katsutoshi Ozaki, +11 authors, Keiya Ozawa.
J Immunol, 2010 Jun 25; 185(3). PMID: 20574002    Free PMC article.
Identification of an immediate Foxp3(-) precursor to Foxp3(+) regulatory T cells in peripheral lymphoid organs of nonmanipulated mice.
Sonja Schallenberg, Pei-Yun Tsai, Julia Riewaldt, Karsten Kretschmer.
J Exp Med, 2010 Jun 30; 207(7). PMID: 20584884    Free PMC article.
Protection against bronchiolitis obliterans syndrome is associated with allograft CCR7+ CD45RA- T regulatory cells.
Aric L Gregson, Aki Hoji, +9 authors, John A Belperio.
PLoS One, 2010 Jul 09; 5(6). PMID: 20613873    Free PMC article.
Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation.
Lai Wei, Golnaz Vahedi, +10 authors, Yuka Kanno.
Immunity, 2010 Jul 14; 32(6). PMID: 20620946    Free PMC article.
Highly Cited.
Expression of 3G11 epitope defines subpopulations of regulatory T cells with different suppressive potency.
Zhao Zhao, Bogoljub Ciric, +5 authors, Abdolmohamad Rostami.
J Neurol Sci, 2010 Jul 14; 295(1-2). PMID: 20621800    Free PMC article.
Interleukin-10 mediated autoregulation of murine B-1 B-cells and its role in Borrelia hermsii infection.
Vishal Sindhava, Michael E Woodman, Brian Stevenson, Subbarao Bondada.
PLoS One, 2010 Jul 14; 5(7). PMID: 20625435    Free PMC article.
Phenotypical and functional alterations of CD8 regulatory T cells in primary biliary cirrhosis.
Francesca Bernuzzi, Daniela Fenoglio, +7 authors, Gilberto Filaci.
J Autoimmun, 2010 Jul 20; 35(3). PMID: 20638239    Free PMC article.
Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis.
Yun Kyung Lee, Juscilene S Menezes, Yoshinori Umesaki, Sarkis K Mazmanian.
Proc Natl Acad Sci U S A, 2010 Jul 28; 108 Suppl 1. PMID: 20660719    Free PMC article.
Highly Cited.
Zoledronic acid impairs myeloid differentiation to tumour-associated macrophages in mesothelioma.
J D Veltman, M E H Lambers, +4 authors, J G J V Aerts.
Br J Cancer, 2010 Jul 29; 103(5). PMID: 20664588    Free PMC article.
Non-human primate regulatory T cells: current biology and implications for transplantation.
Eefje M Dons, Giorgio Raimondi, David K C Cooper, Angus W Thomson.
Transplantation, 2010 Jul 31; 90(8). PMID: 20671597    Free PMC article.
Review.
Direct and indirect roles of the LTbetaR pathway in central tolerance induction.
Mingzhao Zhu, Nicholas K Brown, Yang-Xin Fu.
Trends Immunol, 2010 Aug 03; 31(9). PMID: 20675191    Free PMC article.
CD25 appears non essential for human peripheral T(reg) maintenance in vivo.
Marie-Ghislaine de Goër de Herve, Emmanuel Gonzales, +5 authors, Yassine Taoufik.
PLoS One, 2010 Aug 07; 5(7). PMID: 20689592    Free PMC article.
Hyperactivation of nuclear factor of activated T cells 1 (NFAT1) in T cells attenuates severity of murine autoimmune encephalomyelitis.
Srimoyee Ghosh, Sergei B Koralov, +5 authors, Martin R Müller.
Proc Natl Acad Sci U S A, 2010 Aug 11; 107(34). PMID: 20696888    Free PMC article.
Dendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice.
Cathleen Petzold, Julia Riewaldt, +2 authors, Karsten Kretschmer.
Rev Diabet Stud, 2010 Aug 13; 7(1). PMID: 20703438    Free PMC article.
CD28 exerts protective and detrimental effects in a pulmonary model of paracoccidioidomycosis.
Maíra Felonato, Adriana Pina, +3 authors, Vera L G Calich.
Infect Immun, 2010 Aug 18; 78(11). PMID: 20713624    Free PMC article.
CD4+ CD25+ Foxp3+ regulatory T cells, dendritic cells, and circulating cytokines in uncomplicated malaria: do different parasite species elicit similar host responses?
Raquel M Gonçalves, Karina C Salmazi, +7 authors, Kézia K G Scopel.
Infect Immun, 2010 Aug 18; 78(11). PMID: 20713627    Free PMC article.
Novel role of regulatory T cells in limiting early neutrophil responses in skin.
Hannah Richards, Anwen Williams, +4 authors, Awen Gallimore.
Immunology, 2010 Aug 21; 131(4). PMID: 20722759    Free PMC article.
Effects of irradiating adult mdx mice before full-length dystrophin cDNA transfer on host anti-dystrophin immunity.
S Eghtesad, H Zheng, +2 authors, P R Clemens.
Gene Ther, 2010 Sep 10; 17(9). PMID: 20827278    Free PMC article.
Combined administration of a mutant TGF-beta1/Fc and rapamycin promotes induction of regulatory T cells and islet allograft tolerance.
Wensheng Zhang, Dong Zhang, +5 authors, Xin Xiao Zheng.
J Immunol, 2010 Sep 17; 185(8). PMID: 20844194    Free PMC article.
Control of the specificity of T cell-mediated anti-idiotype immunity by natural regulatory T cells.
Max Warncke, Maike Buchner, +5 authors, Hendrik Veelken.
Cancer Immunol Immunother, 2010 Sep 18; 60(1). PMID: 20848095    Free PMC article.
Human regulatory T cells in autoimmune diseases.
Gregory L Cvetanovich, David A Hafler.
Curr Opin Immunol, 2010 Sep 28; 22(6). PMID: 20869862    Free PMC article.
Review.
Naive human T cells are activated and proliferate in response to the heme oxygenase-1 inhibitor tin mesoporphyrin.
Trevor D Burt, Lillian Seu, +2 authors, Joseph M McCune.
J Immunol, 2010 Oct 06; 185(9). PMID: 20921523    Free PMC article.
Suppression of innate immune pathology by regulatory T cells during Influenza A virus infection of immunodeficient mice.
Inês Antunes, George Kassiotis.
J Virol, 2010 Oct 15; 84(24). PMID: 20943986    Free PMC article.
An intrinsic mechanism predisposes Foxp3-expressing regulatory T cells to Th2 conversion in vivo.
Yunqi Wang, Abdallah Souabni, Richard A Flavell, Yisong Y Wan.
J Immunol, 2010 Oct 15; 185(10). PMID: 20944002    Free PMC article.
Adaptive immunity in the host-microbiota dialog.
T Feng, C O Elson.
Mucosal Immunol, 2010 Oct 15; 4(1). PMID: 20944557    Free PMC article.
Review.
Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia.
V Y Taraban, T J Slebioda, +7 authors, A Al-Shamkhani.
Mucosal Immunol, 2010 Oct 22; 4(2). PMID: 20962771    Free PMC article.
Autoimmunity in Coxsackievirus B3 induced myocarditis: role of estrogen in suppressing autoimmunity.
Future Virol, 2010 Oct 22; 5(3). PMID: 20963181    Free PMC article.
The ligase PIAS1 restricts natural regulatory T cell differentiation by epigenetic repression.
Bin Liu, Samuel Tahk, +2 authors, Ke Shuai.
Science, 2010 Oct 23; 330(6003). PMID: 20966256    Free PMC article.
Immunomodulation for inhibitors in hemophilia A: the important role of Treg cells.
Carol H Miao.
Expert Rev Hematol, 2010 Oct 27; 3(4). PMID: 20976115    Free PMC article.
Review.
Regulatory T cells interfere with glutathione metabolism in dendritic cells and T cells.
Zhonghua Yan, Sanjay K Garg, Ruma Banerjee.
J Biol Chem, 2010 Nov 03; 285(53). PMID: 21037289    Free PMC article.
Immunology: Conditional stability of T cells.
Shimon Sakaguchi.
Nature, 2010 Nov 05; 468(7320). PMID: 21048753
Regulation of tumor immunity by tumor/dendritic cell fusions.
Shigeo Koido, Sadamu Homma, +8 authors, Hisao Tajiri.
Clin Dev Immunol, 2010 Nov 05; 2010. PMID: 21048993    Free PMC article.
Review.
How tolerogenic dendritic cells induce regulatory T cells.
Roberto A Maldonado, Ulrich H von Andrian.
Adv Immunol, 2010 Nov 09; 108. PMID: 21056730    Free PMC article.
Highly Cited. Review.
Regulatory T-cell trafficking: from thymic development to tumor-induced immune suppression.
Adam W Mailloux, M Rita I Young.
Crit Rev Immunol, 2010 Nov 19; 30(5). PMID: 21083525    Free PMC article.
Review.
Signal transduction pathways and transcriptional regulation in Th17 cell differentiation.
Kiyoshi Hirahara, Kamran Ghoreschi, +3 authors, John J O'Shea.
Cytokine Growth Factor Rev, 2010 Nov 19; 21(6). PMID: 21084214    Free PMC article.
Review.
Foxo: in command of T lymphocyte homeostasis and tolerance.
Weiming Ouyang, Ming O Li.
Trends Immunol, 2010 Nov 26; 32(1). PMID: 21106439    Free PMC article.
Review.
CD8 regulates T regulatory cell production of IL-6 and maintains their suppressive phenotype in allergic lung disease.
Anthony Joetham, Masakazu Okamoto, +4 authors, Erwin W Gelfand.
J Immunol, 2010 Dec 01; 186(1). PMID: 21115736    Free PMC article.
The role of HLA-G in immunity and hematopoiesis.
Edgardo D Carosella, Silvia Gregori, +3 authors, Benoit Favier.
Cell Mol Life Sci, 2010 Dec 01; 68(3). PMID: 21116680
Review.
Paradigm shifts in the role of CD4+ T cells in keratoplasty.
Khrishen Cunnusamy, Peter W Chen, Jerry Y Niederkorn.
Discov Med, 2010 Dec 03; 10(54). PMID: 21122477    Free PMC article.
H2 control of natural T regulatory cell frequency in the lymph node correlates with susceptibility to day 3 thymectomy-induced autoimmune disease.
Roxana del Rio, Yuefang Sun, +2 authors, Cory Teuscher.
J Immunol, 2010 Dec 08; 186(1). PMID: 21135167    Free PMC article.
An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness.
Claudio Procaccini, Veronica De Rosa, +8 authors, Giuseppe Matarese.
Immunity, 2010 Dec 15; 33(6). PMID: 21145759    Free PMC article.
Highly Cited.
Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases.
Zaruhi Hovhannisyan, Jacquelyn Treatman, Dan R Littman, Lloyd Mayer.
Gastroenterology, 2010 Dec 15; 140(3). PMID: 21147109    Free PMC article.
Highly Cited.
Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice.
David R Beers, Weihua Zhao, +5 authors, Jenny S Henkel.
Brain Behav Immun, 2010 Dec 24; 25(5). PMID: 21176785    Free PMC article.
CD8α+ plasmacytoid precursor DCs induce antigen-specific regulatory T cells that enhance HSC engraftment in vivo.
Yiming Huang, Larry D Bozulic, +3 authors, Suzanne T Ildstad.
Blood, 2010 Dec 31; 117(8). PMID: 21190989    Free PMC article.
Immunopathology of postprimary tuberculosis: increased T-regulatory cells and DEC-205-positive foamy macrophages in cavitary lesions.
Kerry J Welsh, Semyon A Risin, Jeffrey K Actor, Robert L Hunter.
Clin Dev Immunol, 2011 Jan 05; 2011. PMID: 21197439    Free PMC article.
Has the microbiota played a critical role in the evolution of the adaptive immune system?
Yun Kyung Lee, Sarkis K Mazmanian.
Science, 2011 Jan 06; 330(6012). PMID: 21205662    Free PMC article.
Highly Cited. Review.
Update in the mechanisms of allergen-specific immunotheraphy.
Tunc Akkoc, Mübeccel Akdis, Cezmi A Akdis.
Allergy Asthma Immunol Res, 2011 Jan 11; 3(1). PMID: 21217920    Free PMC article.
CD34+ hematopoietic precursors are present in human decidua and differentiate into natural killer cells upon interaction with stromal cells.
Paola Vacca, Chiara Vitale, +6 authors, Maria Cristina Mingari.
Proc Natl Acad Sci U S A, 2011 Jan 21; 108(6). PMID: 21248224    Free PMC article.
Heterologous immunity: immunopathology, autoimmunity and protection during viral infections.
Liisa K Selin, Myriam F Wlodarczyk, +4 authors, Franco Celada.
Autoimmunity, 2011 Jan 22; 44(4). PMID: 21250837    Free PMC article.
Review.
Cross-talk between cd1d-restricted nkt cells and γδ cells in t regulatory cell response.
Wei Liu, Sally A Huber.
Virol J, 2011 Jan 25; 8. PMID: 21255407    Free PMC article.
Review.
Phenotypical and functional specialization of FOXP3+ regulatory T cells.
Daniel J Campbell, Meghan A Koch.
Nat Rev Immunol, 2011 Jan 27; 11(2). PMID: 21267013    Free PMC article.
Highly Cited. Review.
T-cell subset regulation in atopy.
Marek Jutel, Cezmi A Akdis.
Curr Allergy Asthma Rep, 2011 Jan 29; 11(2). PMID: 21271314    Free PMC article.
Review.
T cell state transition produces an emergent change detector.
Peter S Kim, Peter P Lee.
J Theor Biol, 2011 Feb 01; 275(1). PMID: 21276803    Free PMC article.
Expression of TNFRSF25 on conventional T cells and Tregs.
Vadim Y Taraban, John R Ferdinand, Aymen Al-Shamkhani.
J Clin Invest, 2011 Feb 03; 121(2). PMID: 21285518    Free PMC article.
Visceral adipose inflammation in obesity is associated with critical alterations in tregulatory cell numbers.
Jeffrey Deiuliis, Zubair Shah, +12 authors, Sanjay Rajagopalan.
PLoS One, 2011 Feb 08; 6(1). PMID: 21298111    Free PMC article.
Highly Cited.
CD2 costimulation reveals defective activity by human CD4+CD25(hi) regulatory cells in patients with multiple sclerosis.
Clare M Baecher-Allan, Cristina M Costantino, +4 authors, David A Hafler.
J Immunol, 2011 Feb 09; 186(6). PMID: 21300823    Free PMC article.
Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells.
Masako Saito, Masayuki Nagasawa, +10 authors, Yoshiyuki Minegishi.
J Exp Med, 2011 Feb 09; 208(2). PMID: 21300911    Free PMC article.
Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development.
Yu Lei, Adiratna Mat Ripen, +9 authors, Yousuke Takahama.
J Exp Med, 2011 Feb 09; 208(2). PMID: 21300913    Free PMC article.
Highly Cited.
Evidence that FoxP3+ regulatory T cells may play a role in promoting long-term acceptance of composite tissue allotransplants.
Larry D Bozulic, Yujie Wen, Hong Xu, Suzanne T Ildstad.
Transplantation, 2011 Feb 10; 91(8). PMID: 21304439    Free PMC article.
Immune responses to gut microbiota-commensals and pathogens.
Takeshi Tanoue, Yoshinori Umesaki, Kenya Honda.
Gut Microbes, 2011 Feb 18; 1(4). PMID: 21327029    Free PMC article.
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
Yorifumi Satou, Jun-Ichirou Yasunaga, +11 authors, Masao Matsuoka.
PLoS Pathog, 2011 Feb 25; 7(2). PMID: 21347344    Free PMC article.
Highly Cited.
Tissue-based class control: the other side of tolerance.
Polly Matzinger, Tirumalai Kamala.
Nat Rev Immunol, 2011 Feb 26; 11(3). PMID: 21350581
Highly Cited. Review.
The therapeutic efficacy of human adipose tissue-derived mesenchymal stem cells on experimental autoimmune hearing loss in mice.
Yixuan Zhou, Jingdong Yuan, +4 authors, Tai June Yoo.
Immunology, 2011 Mar 04; 133(1). PMID: 21366561    Free PMC article.
Hepatic stellate cells regulate immune response by way of induction of myeloid suppressor cells in mice.
Hong-Shiue Chou, Ching-Chuan Hsieh, +9 authors, Shiguang Qian.
Hepatology, 2011 Mar 05; 53(3). PMID: 21374665    Free PMC article.
The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells.
Erika Cretney, Annie Xin, +8 authors, Axel Kallies.
Nat Immunol, 2011 Mar 08; 12(4). PMID: 21378976
Highly Cited.
A differential interplay between the expression of Th1/Th2/Treg related cytokine genes in Teladorsagia circumcincta infected DRB1*1101 carrier lambs.
Musa Hassan, James P Hanrahan, +2 authors, Torres Sweeney.
Vet Res, 2011 Mar 10; 42. PMID: 21385411    Free PMC article.
Generation of adaptive regulatory T cells by alloantigen is required for some but not all transplant tolerance protocols.
James I Kim, Matthew R O'connor, +7 authors, James F Markmann.
Transplantation, 2011 Mar 10; 91(7). PMID: 21386770    Free PMC article.
Maturation of effector regulatory T cells.
Naganari Ohkura, Shimon Sakaguchi.
Nat Immunol, 2011 Mar 23; 12(4). PMID: 21423222
Dexamethasone attenuates development of monocrotaline-induced pulmonary arterial hypertension.
Wei Wang, Yu-Lin Wang, +4 authors, Bo Han.
Mol Biol Rep, 2011 Mar 25; 38(5). PMID: 21431360
Antigen-specific blocking of CD4-specific immunological synapse formation using BPI and current therapies for autoimmune diseases.
Prakash Manikwar, Paul Kiptoo, +2 authors, Teruna J Siahaan.
Med Res Rev, 2011 Mar 25; 32(4). PMID: 21433035    Free PMC article.
Review.
Intracerebral human regulatory T cells: analysis of CD4+ CD25+ FOXP3+ T cells in brain lesions and cerebrospinal fluid of multiple sclerosis patients.
Benedikt Fritzsching, Jürgen Haas, +7 authors, Brigitte Wildemann.
PLoS One, 2011 Mar 26; 6(3). PMID: 21437244    Free PMC article.
Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): a myeloid inhibitory receptor involved in immune tolerance.
Hao Cheng, Fiyaz Mohammed, +7 authors, George F Gao.
J Biol Chem, 2011 Apr 02; 286(20). PMID: 21454581    Free PMC article.
Co-inhibitory molecules: Controlling the effectors or controlling the controllers?
Govindarajan Thangavelu, Christa Smolarchuk, Colin C Anderson.
Self Nonself, 2011 Apr 14; 1(2). PMID: 21487510    Free PMC article.
A superagonistic monoclonal antibody for CD28 ameliorates crescentic glomerulonephritis in wistar-kyoto rats.
Yoshitsugu Takabatake, Xiao-Kang Li, +10 authors, Yoshitaka Isaka.
Mol Med, 2011 Apr 14; 17(7-8). PMID: 21487638    Free PMC article.
Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family.
Hélène Bour-Jordan, Jonathan H Esensten, +3 authors, Jeffrey A Bluestone.
Immunol Rev, 2011 Apr 15; 241(1). PMID: 21488898    Free PMC article.
Highly Cited. Review.
The Role of MicroRNAs in Regulatory T Cells and in the Immune Response.
Tai-You Ha.
Immune Netw, 2011 Apr 16; 11(1). PMID: 21494372    Free PMC article.
Contrasting effects of TNF and anti-TNF on the activation of effector T cells and regulatory T cells in autoimmunity.
Xin Chen, Joost J Oppenheim.
FEBS Lett, 2011 Apr 26; 585(23). PMID: 21513711    Free PMC article.
Review.
Regulatory T cells control the Th1 immune response in murine crescentic glomerulonephritis.
Hans-Joachim Paust, Annett Ostmann, +6 authors, Gisa Tiegs.
Kidney Int, 2011 Apr 29; 80(2). PMID: 21525855    Free PMC article.
Efficient induction of CD25- iTreg by co-immunization requires strongly antigenic epitopes for T cells.
Shuang Geng, Yang Yu, +7 authors, Bin Wang.
BMC Immunol, 2011 May 06; 12. PMID: 21542943    Free PMC article.
Nitric oxide modulates TGF-beta-directive signals to suppress Foxp3+ regulatory T cell differentiation and potentiate Th1 development.
Seung-Woo Lee, Heonsik Choi, +2 authors, Michael Croft.
J Immunol, 2011 May 11; 186(12). PMID: 21555530    Free PMC article.
Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice.
Jinlin Liu, Ning Zhang, +6 authors, Honglin Wang.
PLoS One, 2011 May 12; 6(4). PMID: 21559338    Free PMC article.
Maturation of human dendritic cells with Saccharomyces cerevisiae (yeast) reduces the number and function of regulatory T cells and enhances the ratio of antigen-specific effectors to regulatory T cells.
Vittore Cereda, Matteo Vergati, +7 authors, Kwong Y Tsang.
Vaccine, 2011 May 17; 29(31). PMID: 21569810    Free PMC article.
Dynamic palmitoylation and the role of DHHC proteins in T cell activation and anergy.
Nadejda Ladygina, Brent R Martin, Amnon Altman.
Adv Immunol, 2011 May 17; 109. PMID: 21569911    Free PMC article.
Review.
Requirements for prolongation of allograft survival with regulatory T cell infusion in lymphosufficient hosts.
Todd V Brennan, Qizhi Tang, +4 authors, Sang-Mo Kang.
J Surg Res, 2011 May 17; 169(1). PMID: 21571317    Free PMC article.
Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice.
Kenta Misaki, Akio Morinobu, +5 authors, Shunichi Kumagai.
Arthritis Res Ther, 2011 May 20; 13(3). PMID: 21592365    Free PMC article.
Making sense of regulatory T cell suppressive function.
Itay Shalev, Moritz Schmelzle, Simon C Robson, Gary Levy.
Semin Immunol, 2011 May 20; 23(4). PMID: 21592823    Free PMC article.
Review.
Functional regulatory T cells produced by inhibiting cyclic nucleotide phosphodiesterase type 3 prevent allograft rejection.
Gang Feng, Satish N Nadig, +6 authors, Andrew Bushell.
Sci Transl Med, 2011 May 20; 3(83). PMID: 21593400    Free PMC article.
Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis.
David R Beers, Jenny S Henkel, +5 authors, Stanley H Appel.
Brain, 2011 May 21; 134(Pt 5). PMID: 21596768    Free PMC article.
Highly Cited.
Immunomodulatory effects of cyclophosphamide and implementations for vaccine design.
Antonella Sistigu, Sophie Viaud, +3 authors, Laurence Zitvogel.
Semin Immunopathol, 2011 May 26; 33(4). PMID: 21611872
Highly Cited. Review.
CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice.
Christian Weber, Svenja Meiler, +20 authors, Alma Zernecke.
J Clin Invest, 2011 Jun 03; 121(7). PMID: 21633167    Free PMC article.
T regulatory cells participate in the control of germinal centre reactions.
Carla-Maria Alexander, Lorraine T Tygrett, +3 authors, Thomas J Waldschmidt.
Immunology, 2011 Jun 04; 133(4). PMID: 21635248    Free PMC article.
Regulation of bone by the adaptive immune system in arthritis.
Kazuo Okamoto, Hiroshi Takayanagi.
Arthritis Res Ther, 2011 Jun 04; 13(3). PMID: 21635718    Free PMC article.
Review.
Characteristics and PD-1 expression of peripheral CD4+CD127loCD25hiFoxP3+ Treg cells in chronic HCV infected-patients.
Tao Shen, Jiajia Zheng, +5 authors, Fengmin Lu.
Virol J, 2011 Jun 08; 8. PMID: 21645420    Free PMC article.
Type I diabetes-associated tolerogenic properties of interleukin-2.
Aziz Alami Chentoufi, Simon Gaudreau, +3 authors, Geyhad Elghazali.
Clin Dev Immunol, 2011 Jun 08; 2011. PMID: 21647403    Free PMC article.
Innate immune sensors and gastrointestinal bacterial infections.
Georgina L Hold, Indrani Mukhopadhya, Tom P Monie.
Clin Dev Immunol, 2011 Jun 08; 2011. PMID: 21647408    Free PMC article.
Review.
Intranasal delivery of E-selectin reduces atherosclerosis in ApoE-/- mice.
Xinhui Li, Kory R Johnson, +6 authors, Jacqueline A Quandt.
PLoS One, 2011 Jun 28; 6(6). PMID: 21701687    Free PMC article.
Induction of self-antigen-specific Foxp3+ regulatory T cells in the periphery by lymphodepletion treatment with anti-mouse thymocyte globulin in mice.
Yan Lu, Jun Suzuki, +2 authors, Zhibin Chen.
Immunology, 2011 Jun 30; 134(1). PMID: 21711461    Free PMC article.
Role of dendritic cells in the induction of regulatory T cells.
Rahul Kushwah, Jim Hu.
Cell Biosci, 2011 Jun 30; 1(1). PMID: 21711933    Free PMC article.
Polyclonal Treg cells modulate T effector cell trafficking.
Todd S Davidson, Ethan M Shevach.
Eur J Immunol, 2011 Jul 06; 41(10). PMID: 21728170    Free PMC article.
PKC-θ function at the immunological synapse: prospects for therapeutic targeting.
Alexandra Zanin-Zhorov, Michael L Dustin, Bruce R Blazar.
Trends Immunol, 2011 Jul 08; 32(8). PMID: 21733754    Free PMC article.
Review.
Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells.
Ho-Jin Shin, Jeanette Baker, +3 authors, Robert S Negrin.
Blood, 2011 Jul 08; 118(8). PMID: 21734238    Free PMC article.
Regulatory T cells for tolerance therapy: revisiting the concept.
Christian Leguern.
Crit Rev Immunol, 2011 Jul 12; 31(3). PMID: 21740350    Free PMC article.
Review.
Regulatory T cells in CNS injury: the simple, the complex and the confused.
James T Walsh, Jonathan Kipnis.
Trends Mol Med, 2011 Jul 12; 17(10). PMID: 21741881    Free PMC article.
Disturbance of cytokine networks in Sjögren's syndrome.
Pierre Youinou, Jacques-Olivier Pers.
Arthritis Res Ther, 2011 Jul 13; 13(4). PMID: 21745420    Free PMC article.
Review.
Autoimmune regulator (AIRE)-deficient CD8+CD28low regulatory T lymphocytes fail to control experimental colitis.
Céline Pomié, Rita Vicente, +8 authors, Joost P M van Meerwijk.
Proc Natl Acad Sci U S A, 2011 Jul 13; 108(30). PMID: 21746930    Free PMC article.
The molecular mechanisms of Foxp3 gene regulation.
Takashi Maruyama, Joanne E Konkel, Brian F Zamarron, WanJun Chen.
Semin Immunol, 2011 Jul 15; 23(6). PMID: 21752667    Free PMC article.
Review.
Immune dysregulation after cardiothoracic surgery and incidental thymectomy: maintenance of regulatory T cells despite impaired thymopoiesis.
Nancy J Halnon, Paige Cooper, +2 authors, Christel H Uittenbogaart.
Clin Dev Immunol, 2011 Jul 22; 2011. PMID: 21776289    Free PMC article.
Mesenchymal stem cells promote the sustained expression of CD69 on activated T lymphocytes: roles of canonical and non-canonical NF-κB signalling.
Felipe Saldanha-Araujo, Rodrigo Haddad, +8 authors, Rodrigo A Panepucci.
J Cell Mol Med, 2011 Jul 23; 16(6). PMID: 21777379    Free PMC article.
IL-1β promotes TGF-β1 and IL-2 dependent Foxp3 expression in regulatory T cells.
Balaji B Ganesh, Palash Bhattacharya, +3 authors, Bellur S Prabhakar.
PLoS One, 2011 Jul 23; 6(7). PMID: 21779356    Free PMC article.
Signals through 4-1BB inhibit T regulatory cells by blocking IL-9 production enhancing antitumor responses.
Shannon E Smith, Dominique B Hoelzinger, +2 authors, Joseph Lustgarten.
Cancer Immunol Immunother, 2011 Jul 27; 60(12). PMID: 21789593    Free PMC article.
Current concepts of hyperinflammation in chronic granulomatous disease.
Nikolaus Rieber, Andreas Hector, +2 authors, Dominik Hartl.
Clin Dev Immunol, 2011 Aug 03; 2012. PMID: 21808651    Free PMC article.
Review.
Interleukin-10 released by CD4(+)CD25(+) natural regulatory T cells improves microvascular endothelial function through inhibition of NADPH oxidase activity in hypertensive mice.
Modar Kassan, Maria Galan, +2 authors, Khalid Matrougui.
Arterioscler Thromb Vasc Biol, 2011 Aug 06; 31(11). PMID: 21817097    Free PMC article.
Treg cells: patrolling a dangerous neighborhood.
Daniel J Campbell, Meghan A Koch.
Nat Med, 2011 Aug 06; 17(8). PMID: 21818088
Role of cytokines in the pathogenesis and suppression of thyroid autoimmunity.
Balaji B Ganesh, Palash Bhattacharya, Anupama Gopisetty, Bellur S Prabhakar.
J Interferon Cytokine Res, 2011 Aug 10; 31(10). PMID: 21823922    Free PMC article.
Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation.
Marc Beyer, Yasser Thabet, +32 authors, Joachim L Schultze.
Nat Immunol, 2011 Aug 16; 12(9). PMID: 21841785    Free PMC article.
Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1.
Eric V Dang, Joseph Barbi, +15 authors, Fan Pan.
Cell, 2011 Aug 30; 146(5). PMID: 21871655    Free PMC article.
Highly Cited.
Increased frequency of regulatory T cells accompanies increased immune activation in rectal mucosae of HIV-positive noncontrollers.
Julia M Shaw, Peter W Hunt, +6 authors, Barbara L Shacklett.
J Virol, 2011 Sep 02; 85(21). PMID: 21880771    Free PMC article.
Smad4 deficiency in T cells leads to the Th17-associated development of premalignant gastroduodenal lesions in mice.
Jennifer Nancy Hahn, Vincent George Falck, Frank Robert Jirik.
J Clin Invest, 2011 Sep 02; 121(10). PMID: 21881210    Free PMC article.
SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-{gamma} and IL-17A production.
Reiko Takahashi, Shuhei Nishimoto, +7 authors, Akihiko Yoshimura.
J Exp Med, 2011 Sep 07; 208(10). PMID: 21893603    Free PMC article.
Immune interactions in endometriosis.
Jennifer L Herington, Kaylon L Bruner-Tran, John A Lucas, Kevin G Osteen.
Expert Rev Clin Immunol, 2011 Sep 08; 7(5). PMID: 21895474    Free PMC article.
Regulatory T cell: a protection for tumour cells.
Yi Wang, Yushui Ma, +4 authors, Xizhong Shen.
J Cell Mol Med, 2011 Sep 08; 16(3). PMID: 21895966    Free PMC article.
Review.
Low telomerase activity in CD4+ regulatory T cells in patients with severe chronic GVHD after hematopoietic stem cell transplantation.
Yutaka Kawano, Haesook T Kim, +9 authors, Jerome Ritz.
Blood, 2011 Sep 09; 118(18). PMID: 21900196    Free PMC article.
Comparative approach to define increased regulatory T cells in different cancer subtypes by combined assessment of CD127 and FOXP3.
Marc Beyer, Sabine Classen, +5 authors, Joachim L Schultze.
Clin Dev Immunol, 2011 Sep 10; 2011. PMID: 21904560    Free PMC article.
Retinal self-antigen induces a predominantly Th1 effector response in Axl and Mertk double-knockout mice.
Fei Ye, Lixia Han, +6 authors, Qingxian Lu.
J Immunol, 2011 Sep 16; 187(8). PMID: 21918185    Free PMC article.
An essential role of the transcription factor GATA-3 for the function of regulatory T cells.
Yunqi Wang, Maureen A Su, Yisong Y Wan.
Immunity, 2011 Sep 20; 35(3). PMID: 21924928    Free PMC article.
Highly Cited.
Quantitative in situ analysis of FoxP3+ T regulatory cells on transplant tissue using laser scanning cytometry.
Hidenori Takahashi, Phillip Ruiz, +8 authors, Hirohito Ichii.
Cell Transplant, 2011 Sep 21; 21(1). PMID: 21929847    Free PMC article.
The deubiquitinase CYLD targets Smad7 protein to regulate transforming growth factor β (TGF-β) signaling and the development of regulatory T cells.
Yongge Zhao, Angela M Thornton, +5 authors, Ashish Jain.
J Biol Chem, 2011 Sep 21; 286(47). PMID: 21931165    Free PMC article.
Therapeutic effects of novel sphingosine-1-phosphate receptor agonist W-061 in murine DSS colitis.
Yasuaki Sanada, Tsunekazu Mizushima, +6 authors, Toshinori Ito.
PLoS One, 2011 Sep 21; 6(9). PMID: 21931623    Free PMC article.
Higher proportions of circulating FOXP3+ and CTLA-4+ regulatory T cells are associated with lower fractions of memory CD4+ T cells in infants.
Hardis Rabe, Anna-Carin Lundell, +3 authors, Anna Rudin.
J Leukoc Biol, 2011 Sep 22; 90(6). PMID: 21934066    Free PMC article.
Selective recruitment of regulatory T cell through CCR6-CCL20 in hepatocellular carcinoma fosters tumor progression and predicts poor prognosis.
Kang-Jie Chen, Sheng-Zhang Lin, +4 authors, Shu-Sen Zheng.
PLoS One, 2011 Sep 22; 6(9). PMID: 21935436    Free PMC article.
Molecular and functional heterogeneity of T regulatory cells.
Lequn Li, Vassiliki A Boussiotis.
Clin Immunol, 2011 Sep 29; 141(3). PMID: 21945485    Free PMC article.
Review.
Current views on the functions of interleukin-17A-producing cells in atherosclerosis.
M Butcher, E Galkina.
Thromb Haemost, 2011 Sep 29; 106(5). PMID: 21946932    Free PMC article.
Review.
The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development.
Céline Colacios, Audrey Casemayou, +11 authors, Abdelhadi Saoudi.
J Exp Med, 2011 Sep 29; 208(11). PMID: 21948080    Free PMC article.
B cell depletion enhances T regulatory cell activity essential in the suppression of arthritis.
Keith M Hamel, Yanxia Cao, +5 authors, Alison Finnegan.
J Immunol, 2011 Sep 29; 187(9). PMID: 21948985    Free PMC article.
MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis.
Caroline G McPhee, Thomas J Sproule, +6 authors, Derry C Roopenian.
J Immunol, 2011 Oct 04; 187(9). PMID: 21964024    Free PMC article.
Helper T-cell differentiation and plasticity: insights from epigenetics.
Kiyoshi Hirahara, Golnaz Vahedi, +5 authors, Arian Laurence.
Immunology, 2011 Oct 08; 134(3). PMID: 21977994    Free PMC article.
Review.
Respiratory syncytial virus vaccine development.
Julia L Hurwitz.
Expert Rev Vaccines, 2011 Oct 13; 10(10). PMID: 21988307    Free PMC article.
Review.
Human T-lymphotropic virus type 1 (HTLV-1) and regulatory T cells in HTLV-1-associated neuroinflammatory disease.
Natsumi Araya, Tomoo Sato, +4 authors, Yoshihisa Yamano.
Viruses, 2011 Oct 14; 3(9). PMID: 21994794    Free PMC article.
Review.
New frontiers in primary immunodeficiency disorders: immunology and beyond….
Eleonora Gambineri.
Cell Mol Life Sci, 2011 Oct 20; 69(1). PMID: 22009453
Review.
CD4+CD25highFoxP3+ regulatory T-cells in hematologic diseases.
Hee-Won Moon, Bo Hyun Kim, +4 authors, Mark Hong Lee.
Korean J Lab Med, 2011 Oct 22; 31(4). PMID: 22016675    Free PMC article.
c-Rel controls multiple discrete steps in the thymic development of Foxp3+ CD4 regulatory T cells.
George Grigoriadis, Ajithkumar Vasanthakumar, +5 authors, Steve Gerondakis.
PLoS One, 2011 Nov 09; 6(10). PMID: 22066012    Free PMC article.
Cholera-like enterotoxins and Regulatory T cells.
Christelle Basset, Fatou Thiam, +3 authors, Evelyne Kohli.
Toxins (Basel), 2010 Jul 01; 2(7). PMID: 22069660    Free PMC article.
Review.
Unexpected modulation of recall B and T cell responses after immunization with rotavirus-like particles in the presence of LT-R192G.
Fatou Thiam, Cyrille Di Martino, +6 authors, Evelyne Kohli.
Toxins (Basel), 2010 Aug 01; 2(8). PMID: 22069670    Free PMC article.
DNA methylation in inflammatory genes among children with obstructive sleep apnea.
Jinkwan Kim, Rakesh Bhattacharjee, +4 authors, David Gozal.
Am J Respir Crit Care Med, 2011 Nov 15; 185(3). PMID: 22077067    Free PMC article.
Immunotherapy with IL-10- and IFN-γ-producing CD4 effector cells modulate "Natural" and "Inducible" CD4 TReg cell subpopulation levels: observations in four cases of patients with ovarian cancer.
Mark J Dobrzanski, Kathleen A Rewers-Felkins, +5 authors, Stephen E Wright.
Cancer Immunol Immunother, 2011 Nov 16; 61(6). PMID: 22083345    Free PMC article.
Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice.
Uri Sela, Peter Olds, +2 authors, Ralph M Steinman.
J Exp Med, 2011 Nov 16; 208(12). PMID: 22084406    Free PMC article.
Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System.
Manuel Nieto-Sampedro, Beatriz Valle-Argos, +2 authors, Manuel Nieto-Díaz.
Clin Med Insights Oncol, 2011 Nov 16; 5. PMID: 22084619    Free PMC article.
Myeloid dendritic cells isolated from tissues of SIV-infected Rhesus macaques promote the induction of regulatory T cells.
Pietro Presicce, Julia M Shaw, +2 authors, Claire A Chougnet.
AIDS, 2011 Nov 19; 26(3). PMID: 22095196    Free PMC article.
Regulatory T cells essential to prevent the loss of self-tolerance in murine models of erythrocyte-specific autoantibody responses.
Catherine E Calkins.
Immunol Res, 2011 Dec 02; 51(2-3). PMID: 22131153
Review.
Interleukin 10 in the tumor microenvironment: a target for anticancer immunotherapy.
Takami Sato, Mizue Terai, +3 authors, Senthamil R Selvan.
Immunol Res, 2011 Dec 06; 51(2-3). PMID: 22139852
Review.
Manipulating Immune Tolerance with Micro-RNA Regulated Gene Therapy.
Kevin Scott Goudy, Andrea Annoni, Luigi Naldini, Maria-Grazia Roncarolo.
Front Microbiol, 2011 Dec 07; 2. PMID: 22144977    Free PMC article.
Redox outside the box: linking extracellular redox remodeling with intracellular redox metabolism.
Ruma Banerjee.
J Biol Chem, 2011 Dec 08; 287(7). PMID: 22147695    Free PMC article.
Review.
Histamine H4 receptor optimizes T regulatory cell frequency and facilitates anti-inflammatory responses within the central nervous system.
Roxana del Rio, Rajkumar Noubade, +6 authors, Cory Teuscher.
J Immunol, 2011 Dec 08; 188(2). PMID: 22147765    Free PMC article.
Microbial infection-induced expansion of effector T cells overcomes the suppressive effects of regulatory T cells via an IL-2 deprivation mechanism.
Alicia Benson, Sean Murray, +4 authors, Felix Yarovinsky.
J Immunol, 2011 Dec 08; 188(2). PMID: 22147768    Free PMC article.
Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice.
Andréa M Caricilli, Paty K Picardi, +10 authors, Mário J A Saad.
PLoS Biol, 2011 Dec 14; 9(12). PMID: 22162948    Free PMC article.
Highly Cited.
Gene and cell therapy based treatment strategies for inflammatory bowel diseases.
Sander van der Marel, Anna Majowicz, +3 authors, Valerie Ferreira.
World J Gastrointest Pathophysiol, 2011 Dec 20; 2(6). PMID: 22180846    Free PMC article.
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID.
Aisha V Sauer, Immacolata Brigida, +12 authors, Alessandro Aiuti.
Blood, 2011 Dec 21; 119(6). PMID: 22184407    Free PMC article.
Physiological and pathophysiological functions of SOCE in the immune system.
Patrick J Shaw, Stefan Feske.
Front Biosci (Elite Ed), 2011 Dec 29; 4(6). PMID: 22202035    Free PMC article.
Review.
Regulatory T-cell-associated cytokines in systemic lupus erythematosus.
Akiko Okamoto, Keishi Fujio, Tomohisa Okamura, Kazuhiko Yamamoto.
J Biomed Biotechnol, 2012 Jan 06; 2011. PMID: 22219657    Free PMC article.
Review.
Regulation of the inflammatory response in cardiac repair.
Nikolaos G Frangogiannis.
Circ Res, 2012 Jan 10; 110(1). PMID: 22223212    Free PMC article.
Highly Cited. Review.
The microbiome in infectious disease and inflammation.
Kenya Honda, Dan R Littman.
Annu Rev Immunol, 2012 Jan 10; 30. PMID: 22224764    Free PMC article.
Highly Cited. Review.
Re-establishing immunological self-tolerance in autoimmune disease.
Shimon Sakaguchi, Fiona Powrie, Richard M Ransohoff.
Nat Med, 2012 Jan 10; 18(1). PMID: 22227673
Activity of childhood lupus nephritis is linked to altered T cell and cytokine homeostasis.
Monika Edelbauer, Sudhir Kshirsagar, +13 authors, Elisabeth Steichen-Gersdorf.
J Clin Immunol, 2012 Jan 10; 32(3). PMID: 22228566
Increased numbers of Foxp3-positive regulatory T cells in gastritis, peptic ulcer and gastric adenocarcinoma.
Hsin-Hung Cheng, Guan-Ying Tseng, +3 authors, Wen-Ching Wang.
World J Gastroenterol, 2012 Jan 10; 18(1). PMID: 22228968    Free PMC article.
Murine regulatory T cells contain hyperproliferative and death-prone subsets with differential ICOS expression.
Yong Chen, Shudan Shen, +2 authors, Xiao-Ping Zhong.
J Immunol, 2012 Jan 11; 188(4). PMID: 22231701    Free PMC article.
Natural IgM anti-leukocyte autoantibodies attenuate excess inflammation mediated by innate and adaptive immune mechanisms involving Th-17.
Peter I Lobo, Amandeep Bajwa, +8 authors, Mark D Okusa.
J Immunol, 2012 Jan 21; 188(4). PMID: 22262657    Free PMC article.
Mesenchymal stem cells differentially mediate regulatory T cells and conventional effector T cells to protect fully allogeneic islet grafts in mice.
D M Xu, X F Yu, +4 authors, Y C Ding.
Diabetologia, 2012 Jan 25; 55(4). PMID: 22270222
Establishment of nasal tolerance to heat shock protein-60 alleviates atherosclerosis by inducing TGF-β-dependent regulatory T cells.
Haiyu Li, Yanping Ding, +2 authors, Wenkai Yang.
J Huazhong Univ Sci Technolog Med Sci, 2012 Jan 28; 32(1). PMID: 22282240
Controlled release formulations of IL-2, TGF-β1 and rapamycin for the induction of regulatory T cells.
Siddharth Jhunjhunwala, Stephen C Balmert, +4 authors, Steven R Little.
J Control Release, 2012 Jan 31; 159(1). PMID: 22285546    Free PMC article.
Phenotype and function of regulatory T cells in the genital tract.
Janina Jiang, Kathleen A Kelly.
Curr Trends Immunol, 2012 Jan 31; 12. PMID: 22287829    Free PMC article.
Double negative regulatory T cells in transplantation and autoimmunity: recent progress and future directions.
Stephen C Juvet, Li Zhang.
J Mol Cell Biol, 2012 Feb 02; 4(1). PMID: 22294241    Free PMC article.
Review.
MicroRNA profile of circulating CD4-positive regulatory T cells in human adults and impact of differentially expressed microRNAs on expression of two genes essential to their function.
Hussein Fayyad-Kazan, Redouane Rouas, +11 authors, Philippe Martiat.
J Biol Chem, 2012 Feb 02; 287(13). PMID: 22294691    Free PMC article.
Class II MHC self-antigen presentation in human B and T lymphocytes.
Cristina Maria Costantino, Eric Spooner, Hidde L Ploegh, David A Hafler.
PLoS One, 2012 Feb 03; 7(1). PMID: 22299025    Free PMC article.
Unraveling the mystery of the hygiene hypothesis through Helicobacter pylori infection.
Kouji Matsushima, Shigenori Nagai.
J Clin Invest, 2012 Feb 07; 122(3). PMID: 22307323    Free PMC article.
Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function.
Alexandra Zanin-Zhorov, Jiqiang Lin, +7 authors, Michael L Dustin.
Proc Natl Acad Sci U S A, 2012 Feb 07; 109(5). PMID: 22307621    Free PMC article.
Dickkopf-3, an immune modulator in peripheral CD8 T-cell tolerance.
Maria Papatriantafyllou, Gerhard Moldenhauer, +12 authors, Thilo Oelert.
Proc Natl Acad Sci U S A, 2012 Feb 07; 109(5). PMID: 22307622    Free PMC article.
A delicate balance: tweaking IL-2 immunotherapy.
Nat Med, 2012 Feb 09; 18(2). PMID: 22310686
Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells.
Hye-Sook Kwon, Hyung W Lim, +3 authors, Melanie Ott.
J Immunol, 2012 Feb 09; 188(6). PMID: 22312127    Free PMC article.
Extrathymically generated regulatory T cells control mucosal TH2 inflammation.
Steven Z Josefowicz, Rachel E Niec, +5 authors, Alexander Y Rudensky.
Nature, 2012 Feb 10; 482(7385). PMID: 22318520    Free PMC article.
Highly Cited.
Preferential control of induced regulatory T cell homeostasis via a Bim/Bcl-2 axis.
X Wang, A L Szymczak-Workman, +3 authors, D A A Vignali.
Cell Death Dis, 2012 Feb 10; 3. PMID: 22318539    Free PMC article.
Ras inhibition by FTS attenuates brain tumor growth in mice by direct antitumor activity and enhanced reactivity of cytotoxic lymphocytes.
Elizabeta Aizman, Adi Mor, +2 authors, Yoel Kloog.
Oncotarget, 2012 Feb 11; 3(2). PMID: 22323550    Free PMC article.
Expansion of CD4+CD25+FOXP3+ regulatory T cells in infants of mothers with type 1 diabetes.
Kristiina Luopajärvi, Janne K Nieminen, +3 authors, Outi Vaarala.
Pediatr Diabetes, 2012 Feb 16; 13(5). PMID: 22332874    Free PMC article.
Helper T cell diversity and plasticity.
Shingo Nakayamada, Hayato Takahashi, Yuka Kanno, John J O'Shea.
Curr Opin Immunol, 2012 Feb 22; 24(3). PMID: 22341735    Free PMC article.
Highly Cited. Review.
A role for granulocyte-macrophage colony-stimulating factor in the regulation of CD8(+) T cell responses to rabies virus.
Celestine N Wanjalla, Elizabeth F Goldstein, Christoph Wirblich, Matthias J Schnell.
Virology, 2012 Feb 22; 426(2). PMID: 22341782    Free PMC article.
Metabolic pathways in T cell fate and function.
Valerie A Gerriets, Jeffrey C Rathmell.
Trends Immunol, 2012 Feb 22; 33(4). PMID: 22342741    Free PMC article.
Highly Cited. Review.
Thymic gene transfer of myelin oligodendrocyte glycoprotein ameliorates the onset but not the progression of autoimmune demyelination.
Christopher Siatskas, Natalie Seach, +7 authors, Claude C Bernard.
Mol Ther, 2012 Feb 23; 20(7). PMID: 22354375    Free PMC article.
Protective and therapeutic efficacy of Mycobacterium smegmatis expressing HBHA-hIL12 fusion protein against Mycobacterium tuberculosis in mice.
Shanmin Zhao, Yong Zhao, +5 authors, Zhikai Xu.
PLoS One, 2012 Mar 01; 7(2). PMID: 22363768    Free PMC article.
Interleukin-10 plays a crucial role in suppression of experimental autoimmune encephalomyelitis by Bowman-Birk inhibitor.
Hong Dai, Bogoljub Ciric, Guang-Xian Zhang, Abdolmohamad Rostami.
J Neuroimmunol, 2012 Mar 01; 245(1-2). PMID: 22365083    Free PMC article.
Ex vivo expansion of human Tregs by rabbit ATG is dependent on intact STAT3-signaling in CD4⁺ T cells and requires the presence of monocytes.
O Boenisch, M Lopez, +3 authors, N Najafian.
Am J Transplant, 2012 Mar 07; 12(4). PMID: 22390202    Free PMC article.
Historical overview of immunological tolerance.
Ronald H Schwartz.
Cold Spring Harb Perspect Biol, 2012 Mar 08; 4(4). PMID: 22395097    Free PMC article.
Review.
Immunity, cancer and aging: lessons from mouse models.
Cheryl E Myers, Noweeda N Mirza, Joseph Lustgarten.
Aging Dis, 2012 Mar 08; 2(6). PMID: 22396898    Free PMC article.
Mechanisms of inflammatory responses in obese adipose tissue.
Shengyi Sun, Yewei Ji, Sander Kersten, Ling Qi.
Annu Rev Nutr, 2012 Mar 13; 32. PMID: 22404118    Free PMC article.
Highly Cited. Review.
Peptide immunotherapy for childhood allergy - addressing translational challenges.
Karen J Mackenzie, Stephen M Anderton, Jürgen Schwarze.
Clin Transl Allergy, 2011 Jan 01; 1(1). PMID: 22409934    Free PMC article.
A mathematical model of the enhancement of tumor vaccine efficacy by immunotherapy.
Shelby Wilson, Doron Levy.
Bull Math Biol, 2012 Mar 23; 74(7). PMID: 22438084    Free PMC article.
Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells.
Thomas Duhen, Rebekka Duhen, +2 authors, Daniel J Campbell.
Blood, 2012 Mar 23; 119(19). PMID: 22438251    Free PMC article.
Highly Cited.
Immunohistochemical investigation of Foxp3 expression in the intestine in healthy and diseased dogs.
Johannes Junginger, Ulrike Schwittlick, +2 authors, Marion Hewicker-Trautwein.
Vet Res, 2012 Mar 24; 43. PMID: 22440243    Free PMC article.
Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice.
Meilang Xue, Suat Dervish, +2 authors, Christopher J Jackson.
J Biol Chem, 2012 Mar 27; 287(20). PMID: 22447930    Free PMC article.
Foxp3+ regulatory T cells control persistence of viral CNS infection.
Dajana Reuter, Tim Sparwasser, Thomas Hünig, Jürgen Schneider-Schaulies.
PLoS One, 2012 Mar 27; 7(3). PMID: 22448284    Free PMC article.
Self-tolerance in multiple sclerosis.
R E Gonsette.
Acta Neurol Belg, 2012 Mar 28; 112(2). PMID: 22450711    Free PMC article.
Review.
Revisiting the old link between infection and autoimmune disease with commensals and T helper 17 cells.
J Magarian Blander, Miriam B Torchinsky, Laura Campisi.
Immunol Res, 2012 Mar 31; 54(1-3). PMID: 22460741    Free PMC article.
Review.
Loss of T regulatory cell suppression following signaling through glucocorticoid-induced tumor necrosis receptor (GITR) is dependent on c-Jun N-terminal kinase activation.
Anthony Joetham, Hiroshi Ohnishi, +5 authors, Erwin W Gelfand.
J Biol Chem, 2012 Mar 31; 287(21). PMID: 22461627    Free PMC article.
TGF-β converts apoptotic stimuli into the signal for Th9 differentiation.
Mariko Takami, Robert B Love, Makio Iwashima.
J Immunol, 2012 Mar 31; 188(9). PMID: 22461692    Free PMC article.
Cyclosporin but not everolimus inhibits chemokine receptor expression on CD4+ T cell subsets circulating in the peripheral blood of renal transplant recipients.
A Hoerning, S Köhler, +8 authors, O Witzke.
Clin Exp Immunol, 2012 Apr 05; 168(2). PMID: 22471287    Free PMC article.
Interleukin 2 gene polymorphisms are associated with non-Hodgkin lymphoma.
Haihan Song, Lei Chen, Zhanshan Cha, Jianwen Bai.
DNA Cell Biol, 2012 Apr 05; 31(7). PMID: 22472080    Free PMC article.
The pro-metastatic role of bone marrow-derived cells: a focus on MSCs and regulatory T cells.
Bong Ihn Koh, Yibin Kang.
EMBO Rep, 2012 Apr 05; 13(5). PMID: 22473297    Free PMC article.
Review.
Type I interferons maintain Foxp3 expression and T-regulatory cell functions under inflammatory conditions in mice.
Shee Eun Lee, Xiangli Li, +6 authors, Eyal Raz.
Gastroenterology, 2012 Apr 06; 143(1). PMID: 22475534    Free PMC article.
Phenotypic and functional properties of Helios+ regulatory T cells.
Daniel J Zabransky, Christopher J Nirschl, +6 authors, Charles G Drake.
PLoS One, 2012 Apr 06; 7(3). PMID: 22479644    Free PMC article.
Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells.
Jae-Hoon Chang, Yichuan Xiao, +9 authors, Shao-Cong Sun.
Nat Immunol, 2012 Apr 10; 13(5). PMID: 22484734    Free PMC article.
Multiple associations between a broad spectrum of autoimmune diseases, chronic inflammatory diseases and cancer.
Alexis L Franks, Jill E Slansky.
Anticancer Res, 2012 Apr 12; 32(4). PMID: 22493341    Free PMC article.
Review.
Cell-autonomous role of TGFβ and IL-2 receptors in CD4+ and CD8+ inducible regulatory T-cell generation during GVHD.
Norifumi Sawamukai, Atsushi Satake, +4 authors, Taku Kambayashi.
Blood, 2012 Apr 13; 119(23). PMID: 22496155    Free PMC article.
Thymus atrophy and double-positive escape are common features in infectious diseases.
Juliana de Meis, Désio Aurélio Farias-de-Oliveira, +4 authors, Wilson Savino.
J Parasitol Res, 2012 Apr 21; 2012. PMID: 22518275    Free PMC article.
Highlights of the advances in basic immunology in 2011.
Juan Liu, Shuxun Liu, Xuetao Cao.
Cell Mol Immunol, 2012 Apr 24; 9(3). PMID: 22522654    Free PMC article.
Review.
[Mechanism of action of nasal glucocorticosteroids in the treatment of allergic rhinitis. Part 1: Pathophysiology, molecular basis].
L Klimek, P Högger, O Pfaar.
HNO, 2012 Apr 26; 60(7). PMID: 22532281
Regulatory T cells in type 1 autoimmune pancreatitis.
Kazushige Uchida, Takeo Kusuda, +12 authors, Kazuichi Okazaki.
Int J Rheumatol, 2012 Apr 27; 2012. PMID: 22536257    Free PMC article.
Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice.
Fabienne Billiard, Camille Lobry, +19 authors, Dimitris Skokos.
J Exp Med, 2012 May 02; 209(5). PMID: 22547652    Free PMC article.
Role of dendritic cell maturity/costimulation for generation, homeostasis, and suppressive activity of regulatory T cells.
Katrien Pletinckx, Anja Döhler, Vladimir Pavlovic, Manfred B Lutz.
Front Immunol, 2011 Jan 01; 2. PMID: 22566829    Free PMC article.
The molecular mechanisms of regulatory T cell immunosuppression.
Pushpa Pandiyan, Lixin Zheng, Michael J Lenardo.
Front Immunol, 2011 Jan 01; 2. PMID: 22566849    Free PMC article.
The cellular and molecular mechanisms of immuno-suppression by human type 1 regulatory T cells.
Silvia Gregori, Kevin S Goudy, Maria Grazia Roncarolo.
Front Immunol, 2012 May 09; 3. PMID: 22566914    Free PMC article.
The anti-inflammatory mechanisms of Hsp70.
Thiago J Borges, Lotte Wieten, +4 authors, Willem van Eden.
Front Immunol, 2012 May 09; 3. PMID: 22566973    Free PMC article.
Interleukin-7 influences FOXP3+CD4+ regulatory T cells peripheral homeostasis.
Federico Simonetta, Nicolas Gestermann, +4 authors, Christine Bourgeois.
PLoS One, 2012 May 16; 7(5). PMID: 22586481    Free PMC article.
CD25 blockade depletes and selectively reprograms regulatory T cells in concert with immunotherapy in cancer patients.
Andrew J Rech, Rosemarie Mick, +13 authors, Robert H Vonderheide.
Sci Transl Med, 2012 May 18; 4(134). PMID: 22593175    Free PMC article.
Highly Cited.
The immunoregulatory function of vitamin D: implications in chronic kidney disease.
Kevin A Sterling, Parham Eftekhari, +2 authors, Dominic S Raj.
Nat Rev Nephrol, 2012 May 23; 8(7). PMID: 22614789
Review.
Release of dendritic cells from cognate CD4+ T-cell recognition results in impaired peripheral tolerance and fatal cytotoxic T-cell mediated autoimmunity.
Sabine Muth, Kristian Schütze, Hansjörg Schild, Hans Christian Probst.
Proc Natl Acad Sci U S A, 2012 May 23; 109(23). PMID: 22615402    Free PMC article.
Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.
Tadashi Yokosuka, Masako Takamatsu, +3 authors, Takashi Saito.
J Exp Med, 2012 May 30; 209(6). PMID: 22641383    Free PMC article.
Highly Cited.
HTLV-1 modulates the frequency and phenotype of FoxP3+CD4+ T cells in virus-infected individuals.
Yorifumi Satou, Atae Utsunomiya, +3 authors, Masao Matsuoka.
Retrovirology, 2012 Jun 01; 9. PMID: 22647666    Free PMC article.
Hashimoto's Thyroiditis: From Genes to the Disease.
Katja Zaletel, Simona Gaberšček.
Curr Genomics, 2012 Jun 02; 12(8). PMID: 22654557    Free PMC article.
Polarity and lymphocyte fate determination.
John T Chang.
Curr Opin Cell Biol, 2012 Jun 05; 24(4). PMID: 22658837    Free PMC article.
Review.
Biological therapy and the immune system in patients with chronic myeloid leukemia.
Peter Rohon.
Int J Hematol, 2012 Jun 05; 96(1). PMID: 22661045
Review.
The immunology of acute stroke.
Ángel Chamorro, Andreas Meisel, +3 authors, Roland Veltkamp.
Nat Rev Neurol, 2012 Jun 06; 8(7). PMID: 22664787
Highly Cited. Review.
The role of foxp3-expressing regulatory T cells and T helpers in immunopathogenesis of multidrug resistant pulmonary tuberculosis.
E G Churina, O I Urazova, V V Novitskiy.
Tuberc Res Treat, 2012 Jun 06; 2012. PMID: 22666578    Free PMC article.
Cellular and cytokine-dependent immunosuppressive mechanisms of grm1-transgenic murine melanoma.
Miriam Alb, Christopher Sie, +3 authors, David Schrama.
Cancer Immunol Immunother, 2012 Jun 08; 61(12). PMID: 22674057    Free PMC article.
Tolerance-inducing strategies in islet transplantation.
Sumantha Bhatt, John J Fung, Lina Lu, Shiguang Qian.
Int J Endocrinol, 2012 Jun 08; 2012. PMID: 22675353    Free PMC article.
Severe Developmental B Lymphopoietic Defects in Foxp3-Deficient Mice are Refractory to Adoptive Regulatory T Cell Therapy.
Julia Riewaldt, Sandra Düber, +5 authors, Karsten Kretschmer.
Front Immunol, 2012 Jun 09; 3. PMID: 22679447    Free PMC article.
Increased percentages of T helper cells producing IL-17 and monocytes expressing markers of alternative activation in patients with sepsis.
Milena Karina Colo Brunialti, Michelle Carolina Santos, +3 authors, Reinaldo Salomao.
PLoS One, 2012 Jun 14; 7(5). PMID: 22693573    Free PMC article.
Human regulatory T cells induce T-lymphocyte senescence.
Jian Ye, Xingxu Huang, +6 authors, Guangyong Peng.
Blood, 2012 Jun 23; 120(10). PMID: 22723548    Free PMC article.
Significance of the balance between regulatory T (Treg) and T helper 17 (Th17) cells during hepatitis B virus related liver fibrosis.
Jing Li, Shuang-Jian Qiu, +7 authors, Wei Jiang.
PLoS One, 2012 Jun 30; 7(6). PMID: 22745730    Free PMC article.
The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses T(H)2 differentiation.
Makoto Kuwahara, Masakatsu Yamashita, +9 authors, Toshinori Nakayama.
Nat Immunol, 2012 Jul 04; 13(8). PMID: 22751141    Free PMC article.
Multiple treg suppressive modules and their adaptability.
James B Wing, Shimon Sakaguchi.
Front Immunol, 2012 Jul 04; 3. PMID: 22754556    Free PMC article.
Hypoxia-inducible factor 1: A link between metabolism and T cell differentiation and a potential therapeutic target.
Fan Pan, Joseph Barbi, Drew M Pardoll.
Oncoimmunology, 2012 Jul 04; 1(4). PMID: 22754770    Free PMC article.
Regulatory T cells, mTOR kinase, and metabolic activity.
Claudio Procaccini, Giuseppe Matarese.
Cell Mol Life Sci, 2012 Jul 05; 69(23). PMID: 22760498
Review.
Layers of dendritic cell-mediated T cell tolerance, their regulation and the prevention of autoimmunity.
Christian T Mayer, Luciana Berod, Tim Sparwasser.
Front Immunol, 2012 Jul 12; 3. PMID: 22783257    Free PMC article.
Effects of anesthetic methods on preserving anti-tumor T-helper polarization following hepatectomy.
Di Zhou, Fang-Ming Gu, +3 authors, Chang-Hong Miao.
World J Gastroenterol, 2012 Jul 14; 18(24). PMID: 22791944    Free PMC article.
Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanisms.
Weihua Zhao, David R Beers, +2 authors, Stanley H Appel.
Neurobiol Dis, 2012 Jul 24; 48(3). PMID: 22820142    Free PMC article.
Bioinspired controlled release of CCL22 recruits regulatory T cells in vivo.
Siddharth Jhunjhunwala, Giorgio Raimondi, +5 authors, Steven R Little.
Adv Mater, 2012 Jul 24; 24(35). PMID: 22821823    Free PMC article.
CD8+CD45RA+CCR7+FOXP3+ T cells with immunosuppressive properties: a novel subset of inducible human regulatory T cells.
Masakatsu Suzuki, Ann L Jagger, +4 authors, Cornelia M Weyand.
J Immunol, 2012 Jul 24; 189(5). PMID: 22821963    Free PMC article.
Autoimmunity in wiskott-Aldrich syndrome: an unsolved enigma.
Marco Catucci, Maria Carmina Castiello, +2 authors, Anna Villa.
Front Immunol, 2012 Jul 25; 3. PMID: 22826711    Free PMC article.
Tolerance to MHC class II disparate allografts through genetic modification of bone marrow.
P T Jindra, S Tripathi, +2 authors, J Bagley.
Gene Ther, 2012 Jul 27; 20(5). PMID: 22833118    Free PMC article.
Induced and natural regulatory T cells in human cancer.
Theresa L Whiteside, Patrick Schuler, Bastian Schilling.
Expert Opin Biol Ther, 2012 Aug 02; 12(10). PMID: 22849383    Free PMC article.
Review.
Therapeutical measures to control airway tolerance in asthma and lung cancer.
Katerina Andreev, Anna Graser, +2 authors, Susetta Finotto.
Front Immunol, 2012 Aug 03; 3. PMID: 22855687    Free PMC article.
FoxP3⁺ regulatory CD4 T cells control the generation of functional CD8 memory.
M G de Goër de Herve, S Jaafoura, M Vallée, Y Taoufik.
Nat Commun, 2012 Aug 09; 3. PMID: 22871805    Free PMC article.
Intervention of PKC-θ as an immunosuppressive regimen.
Zuoming Sun.
Front Immunol, 2012 Aug 10; 3. PMID: 22876242    Free PMC article.
Involvement of distinct PKC gene products in T cell functions.
Christa Pfeifhofer-Obermair, Nikolaus Thuille, Gottfried Baier.
Front Immunol, 2012 Aug 14; 3. PMID: 22888329    Free PMC article.
Ribavirin modulates the conversion of human CD4(+)  CD25(-) T cell to CD4(+)  CD25(+)  FOXP3(+) T cell via suppressing interleukin-10-producing regulatory T cell.
Tamaki Kobayashi, Katsuhisa Nakatsuka, +6 authors, Choitsu Sakamoto.
Immunology, 2012 Aug 16; 137(3). PMID: 22891772    Free PMC article.
Role of the PD-1 pathway in the immune response.
L V Riella, A M Paterson, A H Sharpe, A Chandraker.
Am J Transplant, 2012 Aug 21; 12(10). PMID: 22900886    Free PMC article.
Highly Cited. Review.
The STAT5b Pathway Defect and Autoimmunity.
Takahiro Kanai, Jennifer Jenks, Kari Christine Nadeau.
Front Immunol, 2012 Aug 23; 3. PMID: 22912632    Free PMC article.
Transcription factor Foxp3 and its protein partners form a complex regulatory network.
Dipayan Rudra, Paul deRoos, +7 authors, Alexander Y Rudensky.
Nat Immunol, 2012 Aug 28; 13(10). PMID: 22922362    Free PMC article.
Highly Cited.
Tumor antigen specific iTreg accumulate in the tumor microenvironment and suppress therapeutic vaccination.
Taylor H Schreiber, Dietlinde Wolf, Maria Bodero, Eckhard Podack.
Oncoimmunology, 2012 Aug 31; 1(5). PMID: 22934256    Free PMC article.
Treg cells, life history, and diversity.
Christophe Benoist, Diane Mathis.
Cold Spring Harb Perspect Biol, 2012 Sep 07; 4(9). PMID: 22952391    Free PMC article.
Review.
T-bet(+) Treg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor β2.
Meghan A Koch, Kerri R Thomas, +3 authors, Daniel J Campbell.
Immunity, 2012 Sep 11; 37(3). PMID: 22960221    Free PMC article.
Highly Cited.
A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells.
Wenxian Fu, Ayla Ergun, +12 authors, Christophe Benoist.
Nat Immunol, 2012 Sep 11; 13(10). PMID: 22961053    Free PMC article.
Highly Cited.
Autoimmune dysregulation and purine metabolism in adenosine deaminase deficiency.
Aisha Vanessa Sauer, Immacolata Brigida, Nicola Carriglio, Alessandro Aiuti.
Front Immunol, 2012 Sep 13; 3. PMID: 22969765    Free PMC article.
Predictors of immunosuppressive regulatory T lymphocytes in healthy women.
Shalaka S Hampras, Mary Nesline, +4 authors, Kirsten B Moysich.
J Cancer Epidemiol, 2012 Sep 13; 2012. PMID: 22969801    Free PMC article.
Dendritic cell-specific disruption of TGF-β receptor II leads to altered regulatory T cell phenotype and spontaneous multiorgan autoimmunity.
Rajalakshmy Ramalingam, Claire B Larmonier, +4 authors, Pawel R Kiela.
J Immunol, 2012 Sep 14; 189(8). PMID: 22972928    Free PMC article.
Regulatory T-cells in chronic lymphocytic leukemia and autoimmune diseases.
Giovanni D'Arena, Giovanni Rossi, +10 authors, Pellegrino Musto.
Mediterr J Hematol Infect Dis, 2012 Sep 14; 4(1). PMID: 22973497    Free PMC article.
T-cell inhibitors: a bench-to-bedside review.
Shinjita Das, Kiyoshi Ariizumi, Ponciano D Cruz.
Dermatitis, 2012 Sep 27; 23(5). PMID: 23010825    Free PMC article.
Review.
Autoimmune manifestations in viral hepatitis.
Diego Vergani, Giorgina Mieli-Vergani.
Semin Immunopathol, 2012 Sep 27; 35(1). PMID: 23010889
Review.
The Therapeutic Potential for PI3K Inhibitors in Autoimmune Rheumatic Diseases.
Edward Banham-Hall, Menna R Clatworthy, Klaus Okkenhaug.
Open Rheumatol J, 2012 Oct 03; 6. PMID: 23028409    Free PMC article.
Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus.
Yoshihiro Ueda, Koko Katagiri, +6 authors, Tatsuo Kinashi.
Nat Commun, 2012 Oct 04; 3. PMID: 23033074
Helminth infections and host immune regulation.
Henry J McSorley, Rick M Maizels.
Clin Microbiol Rev, 2012 Oct 05; 25(4). PMID: 23034321    Free PMC article.
Highly Cited. Review.
Molecular targets related to inflammation and insulin resistance and potential interventions.
Sandro M Hirabara, Renata Gorjão, +3 authors, Rui Curi.
J Biomed Biotechnol, 2012 Oct 11; 2012. PMID: 23049242    Free PMC article.
Review.
Animal models on HTLV-1 and related viruses: what did we learn?
Hiba El Hajj, Rihab Nasr, +6 authors, Ali Bazarbachi.
Front Microbiol, 2012 Oct 11; 3. PMID: 23049525    Free PMC article.
Immunomodulatory effect of vancomycin on Treg in pediatric inflammatory bowel disease and primary sclerosing cholangitis.
David N Abarbanel, Scott M Seki, +5 authors, Kenneth L Cox.
J Clin Immunol, 2012 Oct 12; 33(2). PMID: 23054338    Free PMC article.
Green tea epigallocatechin-3-gallate modulates differentiation of naïve CD4⁺ T cells into specific lineage effector cells.
Junpeng Wang, Munkyong Pae, Simin Nikbin Meydani, Dayong Wu.
J Mol Med (Berl), 2012 Oct 16; 91(4). PMID: 23064699
Technetium-99 conjugated with methylene diphosphonate ameliorates ovariectomy-induced osteoporotic phenotype without causing osteonecrosis in the jaw.
Yinghua Zhao, Lei Wang, +7 authors, Songtao Shi.
Calcif Tissue Int, 2012 Oct 16; 91(6). PMID: 23064899    Free PMC article.
Donor bone marrow-derived T cells inhibit GVHD induced by donor lymphocyte infusion in established mixed allogeneic hematopoietic chimeras.
Hui Wang, Yanping Yang, +4 authors, Yong-Guang Yang.
PLoS One, 2012 Oct 19; 7(10). PMID: 23077554    Free PMC article.
Novel developments in the mechanisms of immune tolerance to allergens.
Thomas Eiwegger, Saskia Gruber, Zsolt Szépfalusi, Cezmi A Akdis.
Hum Vaccin Immunother, 2012 Oct 26; 8(10). PMID: 23095863    Free PMC article.
Review.
Induction and regulation of pathogenic Th17 cell responses in schistosomiasis.
Bridget M Larkin, Patrick M Smith, +3 authors, Miguel J Stadecker.
Semin Immunopathol, 2012 Oct 26; 34(6). PMID: 23096253    Free PMC article.
Review.
Cellular immune suppressor mechanisms in patients with hepatocellular carcinoma.
Fei Zhao, Firouzeh Korangy, Tim F Greten.
Dig Dis, 2012 Oct 31; 30(5). PMID: 23108303    Free PMC article.
Review.
A cancer vaccine induces expansion of NY-ESO-1-specific regulatory T cells in patients with advanced melanoma.
Lisa M Ebert, Sarah E MacRaild, +3 authors, Weisan Chen.
PLoS One, 2012 Oct 31; 7(10). PMID: 23110239    Free PMC article.
Combination peptide immunotherapy based on T-cell epitope mapping reduces allergen-specific IgE and eosinophilia in allergic airway inflammation.
Karen J Mackenzie, Paul M Fitch, +6 authors, Jürgen Schwarze.
Immunology, 2012 Nov 02; 138(3). PMID: 23113712    Free PMC article.
Helminth infection in populations undergoing epidemiological transition: a friend or foe?
Aprilianto Eddy Wiria, Yenny Djuardi, +2 authors, Maria Yazdanbakhsh.
Semin Immunopathol, 2012 Nov 07; 34(6). PMID: 23129304
Review.
Novel Foxo1-dependent transcriptional programs control T(reg) cell function.
Weiming Ouyang, Will Liao, +13 authors, Ming O Li.
Nature, 2012 Nov 09; 491(7425). PMID: 23135404    Free PMC article.
Highly Cited.
Dendritic cell-directed vaccination with a lentivector encoding PSCA for prostate cancer in mice.
Liang Xiao, Kye-Il Joo, Matthew Lim, Pin Wang.
PLoS One, 2012 Nov 10; 7(11). PMID: 23139820    Free PMC article.
Tumour-infiltrating FOXP3(+) lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer.
N R West, S E Kost, +4 authors, P H Watson.
Br J Cancer, 2012 Nov 22; 108(1). PMID: 23169287    Free PMC article.
Human umbilical cord mesenchymal stem cells as treatment of adjuvant rheumatoid arthritis in a rat model.
Sahar Greish, Noha Abogresha, +3 authors, Mohamed Hefny.
World J Stem Cells, 2012 Nov 29; 4(10). PMID: 23189211    Free PMC article.
Single nucleotide polymorphisms in the promoter regions of Foxp3 and ICOSLG genes are associated with Alopecia areata.
G Conteduca, A Rossi, +11 authors, G Filaci.
Clin Exp Med, 2012 Dec 01; 14(1). PMID: 23196741
Molecular and Cellular Mechanism of Leukemogenesis of ATL: Emergent Evidence of a Significant Role for HBZ in HTLV-1-Induced Pathogenesis.
Yorifumi Satou, Masao Matsuoka.
Leuk Res Treatment, 2012 Dec 01; 2012. PMID: 23198153    Free PMC article.
Immune tolerance and transplantation.
Onder Alpdogan, Marcel R M van den Brink.
Semin Oncol, 2012 Dec 05; 39(6). PMID: 23206840    Free PMC article.
Review.
Regulatory T cells in children with recently diagnosed type 1 diabetes.
Asmaa Mohamed Zahran, Khalid Ibrahem Elsayh, Kotb Abbass Metwalley.
Indian J Endocrinol Metab, 2012 Dec 12; 16(6). PMID: 23226641    Free PMC article.
The need for inducing tolerance in vascularized composite allotransplantation.
Kadiyala V Ravindra, Hong Xu, +2 authors, Suzanne T Ildstad.
Clin Dev Immunol, 2012 Dec 20; 2012. PMID: 23251216    Free PMC article.
Review.
Regulatory T cells in HIV infection: can immunotherapy regulate the regulator?
Mohammad-Ali Jenabian, Petronela Ancuta, Norbert Gilmore, Jean-Pierre Routy.
Clin Dev Immunol, 2012 Dec 20; 2012. PMID: 23251223    Free PMC article.
Review.
Functional defect in regulatory T cells in myasthenia gravis.
Muthusamy Thiruppathi, Julie Rowin, +3 authors, Matthew N Meriggioli.
Ann N Y Acad Sci, 2012 Dec 21; 1274. PMID: 23252899    Free PMC article.
Review.
A study of circulating anti-CD25 antibodies in non-small cell lung cancer.
L Ye, X Li, +6 authors, B Liu.
Clin Transl Oncol, 2012 Dec 25; 15(8). PMID: 23263913
Dendritic cells from oral cavity induce Foxp3(+) regulatory T cells upon antigen stimulation.
Sayuri Yamazaki, Akira Maruyama, +3 authors, Tsukasa Seya.
PLoS One, 2012 Dec 29; 7(12). PMID: 23272135    Free PMC article.
Long-term engraftment of human natural T regulatory cells in NOD/SCID IL2rγc(null) mice by expression of human IL-2.
Sojan Abraham, Rajendra Pahwa, +7 authors, Premlata Shankar.
PLoS One, 2012 Dec 29; 7(12). PMID: 23272176    Free PMC article.
Helios induces epigenetic silencing of IL2 gene expression in regulatory T cells.
Ian Baine, Samik Basu, +2 authors, Fernando Macian.
J Immunol, 2013 Jan 01; 190(3). PMID: 23275607    Free PMC article.
Varicella zoster-specific CD4+Foxp3+ T cells accumulate after cutaneous antigen challenge in humans.
Milica Vukmanovic-Stejic, Daisy Sandhu, +11 authors, Arne N Akbar.
J Immunol, 2013 Jan 04; 190(3). PMID: 23284056    Free PMC article.
Study of regulatory T-cells in patients with gastric malt lymphoma: influence on treatment response and outcome.
Mar García, Beatriz Bellosillo, +10 authors, Antonio Salar.
PLoS One, 2013 Jan 04; 7(12). PMID: 23284739    Free PMC article.
Natalizumab exerts direct signaling capacity and supports a pro-inflammatory phenotype in some patients with multiple sclerosis.
Thomas F Benkert, Lena Dietz, +5 authors, Friederike Berberich-Siebelt.
PLoS One, 2013 Jan 04; 7(12). PMID: 23284936    Free PMC article.
Tolerance and autoimmunity in primary immunodeficiency disease: a comprehensive review.
Sudhir Gupta, Ankmalika Gupta Louis.
Clin Rev Allergy Immunol, 2013 Jan 09; 45(2). PMID: 23296947
Review.
Application of dendritic cells stimulated with Trichinella spiralis excretory-secretory antigens alleviates experimental autoimmune encephalomyelitis.
L J Sofronic-Milosavljevic, I Radovic, +3 authors, A Gruden-Movsesijan.
Med Microbiol Immunol, 2013 Jan 12; 202(3). PMID: 23307236
BRG1-mediated immune tolerance: facilitation of Treg activation and partial independence of chromatin remodelling.
Barbara H Chaiyachati, Anant Jani, +3 authors, Tian Chi.
EMBO J, 2013 Jan 17; 32(3). PMID: 23321680    Free PMC article.
Ontogeny and localization of the cells produce IL-2 in healthy animals.
Mutsumi Yamamoto, Yoichi Seki, +6 authors, Makio Iwashima.
Cytokine, 2013 Jan 22; 61(3). PMID: 23332616    Free PMC article.
SMAD regulatory networks construct a balanced immune system.
Nidhi Malhotra, Joonsoo Kang.
Immunology, 2013 Jan 26; 139(1). PMID: 23347175    Free PMC article.
Review.
Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease.
Kylie D Mason, Ann Lin, +9 authors, Lorraine A O'Reilly.
Proc Natl Acad Sci U S A, 2013 Jan 26; 110(7). PMID: 23349374    Free PMC article.
Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy.
Wei Liao, Jian-Xin Lin, Warren J Leonard.
Immunity, 2013 Jan 29; 38(1). PMID: 23352221    Free PMC article.
Highly Cited. Review.
Regulatory T-cells in chronic lymphocytic leukemia: actor or innocent bystander?
Giovanni D'Arena, Vittorio Simeon, +7 authors, Vincenzo De Feo.
Am J Blood Res, 2013 Jan 30; 3(1). PMID: 23358515    Free PMC article.
CD8⁺CXCR5⁺ T cells regulate pathology in the genital tract.
Janina Jiang, Cheryl I Champion, +2 authors, Kathleen A Kelly.
Infect Dis Obstet Gynecol, 2013 Feb 01; 2013. PMID: 23365491    Free PMC article.
Immunomodulatory effects of total intravenous and balanced inhalation anesthesia in patients with bladder cancer undergoing elective radical cystectomy: preliminary results.
Maria Sofra, Paola Cordiali Fei, +5 authors, Ester Forastiere.
J Exp Clin Cancer Res, 2013 Feb 05; 32. PMID: 23374147    Free PMC article.
Colonic immune stimulation by targeted oral vaccine.
Mahesh Kathania, Mojgan Zadeh, +4 authors, Mansour Mohamadzadeh.
PLoS One, 2013 Feb 06; 8(1). PMID: 23383086    Free PMC article.
Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells.
Yutaka Kurebayashi, Shigenori Nagai, Ai Ikejiri, Shigeo Koyasu.
Genes Cells, 2013 Feb 07; 18(4). PMID: 23383714    Free PMC article.
Review.
Identification of the E3 deubiquitinase ubiquitin-specific peptidase 21 (USP21) as a positive regulator of the transcription factor GATA3.
Jing Zhang, Chen Chen, +11 authors, Bin Li.
J Biol Chem, 2013 Feb 12; 288(13). PMID: 23395819    Free PMC article.
Adoptive transfer of human gingiva-derived mesenchymal stem cells ameliorates collagen-induced arthritis via suppression of Th1 and Th17 cells and enhancement of regulatory T cell differentiation.
Maogen Chen, Wenru Su, +10 authors, Song Guo Zheng.
Arthritis Rheum, 2013 Feb 13; 65(5). PMID: 23400582    Free PMC article.
Highly Cited.
Helper T-cell identity and evolution of differential transcriptomes and epigenomes.
Golnaz Vahedi, Amanda C Poholek, +4 authors, Kiyoshi Hirahara.
Immunol Rev, 2013 Feb 15; 252(1). PMID: 23405893    Free PMC article.
Review.
Metabolic control of the Treg/Th17 axis.
Joseph Barbi, Drew Pardoll, Fan Pan.
Immunol Rev, 2013 Feb 15; 252(1). PMID: 23405895    Free PMC article.
Highly Cited. Review.
CD4(+) T-cell subsets in intestinal inflammation.
Matthew Shale, Chris Schiering, Fiona Powrie.
Immunol Rev, 2013 Feb 15; 252(1). PMID: 23405904    Free PMC article.
Review.
Immune response from a resource allocation perspective.
Wendy M Rauw.
Front Genet, 2013 Feb 16; 3. PMID: 23413205    Free PMC article.
Circulating autoantibody to CD25 may be a potential biomarker for early diagnosis of esophageal squamous cell carcinoma.
S Guan, B Liu, +3 authors, J Wei.
Clin Transl Oncol, 2013 Feb 21; 15(10). PMID: 23423807
In and out of the bull's eye: protein kinase Cs in the immunological synapse.
Kok-Fai Kong, Amnon Altman.
Trends Immunol, 2013 Feb 23; 34(5). PMID: 23428395    Free PMC article.
Review.
Fetal regulatory T cells and peripheral immune tolerance in utero: implications for development and disease.
Trevor D Burt.
Am J Reprod Immunol, 2013 Feb 26; 69(4). PMID: 23432802    Free PMC article.
Review.
The yin and yang of protein kinase C-theta (PKCθ): a novel drug target for selective immunosuppression.
Elizabeth Yan Zhang, Kok-Fai Kong, Amnon Altman.
Adv Pharmacol, 2013 Feb 26; 66. PMID: 23433459    Free PMC article.
Review.
Regulation of nuclear factor-κB in autoimmunity.
Shao-Cong Sun, Jae-Hoon Chang, Jin Jin.
Trends Immunol, 2013 Feb 26; 34(6). PMID: 23434408    Free PMC article.
Review.
The importance of the nurse cells and regulatory cells in the control of T lymphocyte responses.
María Guadalupe Reyes García, Fernando García Tamayo.
Biomed Res Int, 2013 Mar 20; 2013. PMID: 23509712    Free PMC article.
Review.
Immunological cells and functions in Gaucher disease.
Manoj Kumar Pandey, Gregory A Grabowski.
Crit Rev Oncog, 2013 Mar 21; 18(3). PMID: 23510064    Free PMC article.
Review.
PD-L1/PD-1 Co-Stimulation, a Brake for T cell Activation and a T cell Differentiation Signal.
Therese Liechtenstein, Ines Dufait, +4 authors, David Escors.
J Clin Cell Immunol, 2013 Mar 26; S12. PMID: 23525238    Free PMC article.
Retroviral and lentiviral vectors for the induction of immunological tolerance.
Inès Dufait, Therese Liechtenstein, +5 authors, David Escors.
Scientifica (Cairo), 2013 Mar 26; 2012. PMID: 23526794    Free PMC article.
Information-theoretic analysis of the dynamics of an executable biological model.
Avital Sadot, Septimia Sarbu, +4 authors, Ilya Shmulevich.
PLoS One, 2013 Mar 26; 8(3). PMID: 23527156    Free PMC article.
Identification of cytolytic CD161- CD56+ regulatory CD8 T cells in human peripheral blood.
Dan Hu, Howard L Weiner, Jerome Ritz.
PLoS One, 2013 Mar 26; 8(3). PMID: 23527216    Free PMC article.
The role of glutamate and the immune system in organophosphate-induced CNS damage.
Arik Eisenkraft, Avshalom Falk, Arseny Finkelstein.
Neurotox Res, 2013 Mar 28; 24(2). PMID: 23532600
Review.
Expanding roles for CD4 T cells and their subpopulations in tumor immunity and therapy.
Mark J Dobrzanski.
Front Oncol, 2013 Mar 28; 3. PMID: 23533029    Free PMC article.
The serum IL-6 profile and Treg/Th17 peripheral cell populations in patients with type 1 diabetes.
Monika Ryba-Stanisławowska, Maria Skrzypkowska, Jolanta Myśliwska, Małgorzata Myśliwiec.
Mediators Inflamm, 2013 Mar 28; 2013. PMID: 23533301    Free PMC article.
Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway.
Jonathan M Coquet, Julie C Ribot, +9 authors, Jannie Borst.
J Exp Med, 2013 Apr 03; 210(4). PMID: 23547099    Free PMC article.
Regulatory T-cell immunotherapy for allogeneic hematopoietic stem-cell transplantation.
Matthew Horch, Vu H Nguyen.
Ther Adv Hematol, 2012 Feb 01; 3(1). PMID: 23556110    Free PMC article.
Role of T cell death in maintaining immune tolerance during persistent viral hepatitis.
Juan Ramón Larrubia, Megha Uttam Lokhande, +3 authors, Eduardo Sanz-de-Villalobos.
World J Gastroenterol, 2013 Apr 10; 19(12). PMID: 23569333    Free PMC article.
Review.
GARP-TGF-β complexes negatively regulate regulatory T cell development and maintenance of peripheral CD4+ T cells in vivo.
Angela X Zhou, Lina Kozhaya, Hodaka Fujii, Derya Unutmaz.
J Immunol, 2013 Apr 12; 190(10). PMID: 23576681    Free PMC article.
Regulatory T cell phenotype and function 4 years after GAD-alum treatment in children with type 1 diabetes.
M Pihl, L Akerman, +5 authors, R Casas.
Clin Exp Immunol, 2013 Apr 23; 172(3). PMID: 23600827    Free PMC article.
The liver works as a school to educate regulatory immune cells.
Fenglei Li, Zhigang Tian.
Cell Mol Immunol, 2013 Apr 23; 10(4). PMID: 23604044    Free PMC article.
Review.
Targeting purinergic receptors in islet transplantation.
Reid A Aikin.
Diabetes, 2013 Apr 25; 62(5). PMID: 23613563    Free PMC article.
Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease.
Kiyoshi Hirahara, Amanda Poholek, +4 authors, John J O'Shea.
J Allergy Clin Immunol, 2013 Apr 30; 131(5). PMID: 23622118    Free PMC article.
Review.
T-cell tolerance in cancer.
Roza Nurieva, Junmei Wang, Anupama Sahoo.
Immunotherapy, 2013 May 04; 5(5). PMID: 23638746    Free PMC article.
Review.
Genetic polymorphism in FOXP3 gene: imbalance in regulatory T-cell role and development of human diseases.
Julie Massayo Maeda Oda, Bruna Karina Banin Hirata, Roberta Losi Guembarovski, Maria Angelica Ehara Watanabe.
J Genet, 2013 May 04; 92(1). PMID: 23640423
Review.
IL-2-independent and TNF-α-dependent expansion of Vβ5+ natural regulatory T cells during retrovirus infection.
Lara Myers, Jara J Joedicke, +5 authors, Kim J Hasenkrug.
J Immunol, 2013 May 07; 190(11). PMID: 23645880    Free PMC article.
Identification of CD3+CD4-CD8- T cells as potential regulatory cells in an experimental murine model of graft-versus-host skin disease (GVHD).
Fumi Miyagawa, Naoko Okiyama, Vadim Villarroel, Stephen I Katz.
J Invest Dermatol, 2013 May 08; 133(11). PMID: 23648548    Free PMC article.
Distinct translational control in CD4+ T cell subsets.
Eva Bjur, Ola Larsson, +7 authors, Ciriaco A Piccirillo.
PLoS Genet, 2013 May 10; 9(5). PMID: 23658533    Free PMC article.
Comparative analysis of cancer vaccine settings for the selection of an effective protocol in mice.
Francesca Kalli, Rodolfo Machiorlatti, +11 authors, Gilberto Filaci.
J Transl Med, 2013 May 15; 11. PMID: 23663506    Free PMC article.
Peripheral Treg count and it's determinants in unsensitized and sensitized chronic kidney disease patients.
Cansu Topal, Sadi Köksoy, +2 authors, F Fevzi Ersoy.
Int Urol Nephrol, 2013 May 16; 45(6). PMID: 23673776
The plasticity and stability of regulatory T cells.
Shimon Sakaguchi, Dario A A Vignali, +2 authors, Herman Waldmann.
Nat Rev Immunol, 2013 May 18; 13(6). PMID: 23681097
Highly Cited.
T cell receptor (TCR) and transforming growth factor β (TGF-β) signaling converge on DNA (cytosine-5)-methyltransferase to control forkhead box protein 3 (foxp3) locus methylation and inducible regulatory T cell differentiation.
Chaoran Li, Peter J R Ebert, Qi-Jing Li.
J Biol Chem, 2013 May 21; 288(26). PMID: 23687305    Free PMC article.
Cutting edge: Receptors for C3a and C5a modulate stability of alloantigen-reactive induced regulatory T cells.
William van der Touw, Paolo Cravedi, +3 authors, Peter S Heeger.
J Immunol, 2013 May 22; 190(12). PMID: 23690475    Free PMC article.
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression.
Tomoyuki Yamaguchi, Ayumi Kishi, +5 authors, Shimon Sakaguchi.
Proc Natl Acad Sci U S A, 2013 May 22; 110(23). PMID: 23690575    Free PMC article.
Foxp3(+) regulatory T cells in mouse models of type 1 diabetes.
Cathleen Petzold, Julia Riewaldt, +3 authors, Karsten Kretschmer.
J Diabetes Res, 2013 May 22; 2013. PMID: 23691523    Free PMC article.
IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection.
Iwana Schmitz, Christoph Schneider, +7 authors, Manfred Kopf.
PLoS Pathog, 2013 May 23; 9(5). PMID: 23696736    Free PMC article.
Stable graft function on low-dose steroid monotherapy in spite of donor-specific antibodies in renal transplantation combined with stem cell infusion.
Hargovind L Trivedi, Aruna V Vanikar, Shruti D Dave.
BMJ Case Rep, 2013 Jun 05; 2013. PMID: 23729716    Free PMC article.
Alterations in circulating T-cell lymphocyte populations in children with obstructive sleep apnea.
Hui-Leng Tan, David Gozal, +4 authors, Leila Kheirandish-Gozal.
Sleep, 2013 Jun 05; 36(6). PMID: 23729935    Free PMC article.
Regulatory CD8+ T cells associated with erosion of immune surveillance in persistent virus infection suppress in vitro and have a reversible proliferative defect.
Zhuting Hu, Weijun Zhang, Edward J Usherwood.
J Immunol, 2013 Jun 05; 191(1). PMID: 23733872    Free PMC article.
Cutting edge: inhaled antigen upregulates retinaldehyde dehydrogenase in lung CD103+ but not plasmacytoid dendritic cells to induce Foxp3 de novo in CD4+ T cells and promote airway tolerance.
Anupriya Khare, Nandini Krishnamoorthy, +3 authors, Anuradha Ray.
J Immunol, 2013 Jun 05; 191(1). PMID: 23733880    Free PMC article.
Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals.
Xuguang Tai, Batu Erman, +9 authors, Alfred Singer.
Immunity, 2013 Jun 12; 38(6). PMID: 23746651    Free PMC article.
Highly Cited.
The role of CARMA1 in T cells.
Marly I Roche, Ravisankar A Ramadas, Benjamin D Medoff.
Crit Rev Immunol, 2013 Jun 13; 33(3). PMID: 23756245    Free PMC article.
Review.
The role of IL-17-producing Foxp3+ CD4+ T cells in inflammatory bowel disease and colon cancer.
Lequn Li, Vassiliki A Boussiotis.
Clin Immunol, 2013 Jun 19; 148(2). PMID: 23773923    Free PMC article.
Review.
Pathogen-specific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12.
Shahin Shafiani, Crystal Dinh, +7 authors, Kevin B Urdahl.
Immunity, 2013 Jun 25; 38(6). PMID: 23791647    Free PMC article.
Chloroquine treatment enhances regulatory T cells and reduces the severity of experimental autoimmune encephalomyelitis.
Rodolfo Thomé, Adriel S Moraes, +7 authors, Liana Verinaud.
PLoS One, 2013 Jun 27; 8(6). PMID: 23799062    Free PMC article.
Dendritic cells in the periphery control antigen-specific natural and induced regulatory T cells.
Sayuri Yamazaki, Akimichi Morita.
Front Immunol, 2013 Jun 27; 4. PMID: 23801989    Free PMC article.
Thymic versus induced regulatory T cells - who regulates the regulators?
Giovanni Antonio Maria Povoleri, Cristiano Scottà, +3 authors, Behdad Afzali.
Front Immunol, 2013 Jul 03; 4. PMID: 23818888    Free PMC article.
Mechanism of immune tolerance induced by donor derived immature dendritic cells in rat high-risk corneal transplantation.
Xiao-Wei Gao, Yan Fu, +3 authors, Xu-Dong Zhao.
Int J Ophthalmol, 2013 Jul 05; 6(3). PMID: 23826517    Free PMC article.
CD8(+) T cells in multiple sclerosis.
Aleksandar Denic, Bharath Wootla, Moses Rodriguez.
Expert Opin Ther Targets, 2013 Jul 09; 17(9). PMID: 23829711    Free PMC article.
Review.
Differential targeting of IL-2 and T cell receptor signaling pathways selectively expands regulatory T cells while inhibiting conventional T cells.
Atsushi Satake, Amanda M Schmidt, +3 authors, Taku Kambayashi.
J Autoimmun, 2013 Jul 10; 44. PMID: 23834842    Free PMC article.
Regulatory T cells in the immunodiagnosis and outcome of kidney allograft rejection.
O Franzese, A Mascali, +3 authors, N Di Daniele.
Clin Dev Immunol, 2013 Jul 12; 2013. PMID: 23843861    Free PMC article.
Review.
Apoptotic cell administration enhances pancreatic islet engraftment by induction of regulatory T cells and tolerogenic dendritic cells.
Cong Wu, Yi Zhang, +5 authors, Guoyou Chen.
Cell Mol Immunol, 2013 Jul 23; 10(5). PMID: 23872920    Free PMC article.
Natural and induced T regulatory cells in cancer.
Dennis O Adeegbe, Hiroyoshi Nishikawa.
Front Immunol, 2013 Jul 23; 4. PMID: 23874336    Free PMC article.
Highly Cited.
Home sweet home: the tumor microenvironment as a haven for regulatory T cells.
Beatrice Ondondo, Emma Jones, Andrew Godkin, Awen Gallimore.
Front Immunol, 2013 Jul 23; 4. PMID: 23874342    Free PMC article.
Natural Killer Dendritic Cells Enhance Immune Responses Elicited by α -Galactosylceramide-Stimulated Natural Killer T Cells.
Sung Won Lee, Hyun Jung Park, Nayoung Kim, Seokmann Hong.
Biomed Res Int, 2013 Jul 24; 2013. PMID: 23878807    Free PMC article.
The role of ubiquitin ligases in the control of organ specific autoimmunity.
Gerard F Hoyne.
Am J Clin Exp Immunol, 2012 Jan 01; 1(2). PMID: 23885319    Free PMC article.
Combining genetic mapping with genome-wide expression in experimental autoimmune encephalomyelitis highlights a gene network enriched for T cell functions and candidate genes regulating autoimmunity.
Melanie Thessen Hedreul, Steffen Möller, +8 authors, Maja Jagodic.
Hum Mol Genet, 2013 Aug 01; 22(24). PMID: 23900079    Free PMC article.
Human regulatory T cells against minor histocompatibility antigens: ex vivo expansion for prevention of graft-versus-host disease.
Anandharaman Veerapathran, Joseph Pidala, +7 authors, Claudio Anasetti.
Blood, 2013 Aug 03; 122(13). PMID: 23908471    Free PMC article.
Serine protease inhibitor 6 plays a critical role in protecting murine granzyme B-producing regulatory T cells.
Jamil Azzi, Nikolaos Skartsis, +13 authors, Reza Abdi.
J Immunol, 2013 Aug 06; 191(5). PMID: 23913965    Free PMC article.
T helper cell polarization in healthy people: implications for cardiovascular disease.
Nels C Olson, Reem Sallam, +2 authors, Sally A Huber.
J Cardiovasc Transl Res, 2013 Aug 08; 6(5). PMID: 23921946    Free PMC article.
Review.
T cell Receptor Signal Transduction in T lymphocytes.
Balachandra K Gorentla, Xiao-Ping Zhong.
J Clin Cell Immunol, 2013 Aug 16; 2012(Suppl 12). PMID: 23946894    Free PMC article.
Peripheral and thymic foxp3(+) regulatory T cells in search of origin, distinction, and function.
Chetan Dhamne, Yeonseok Chung, +2 authors, Dat Quoc Tran.
Front Immunol, 2013 Aug 30; 4. PMID: 23986762    Free PMC article.
Regulatory T cells and Atherosclerosis.
Jahaira Lopez Pastrana, Xiaojin Sha, +5 authors, Xiao-Feng Yang.
J Clin Exp Cardiolog, 2013 Sep 03; 2012(Suppl 12). PMID: 23997979    Free PMC article.
Antibodies targeting human OX40 expand effector T cells and block inducible and natural regulatory T cell function.
Kui S Voo, Laura Bover, +5 authors, Yong J Liu.
J Immunol, 2013 Sep 10; 191(7). PMID: 24014877    Free PMC article.
IL-9 and Th9 cells: progress and challenges.
Picheng Zhao, Xiang Xiao, Rafik M Ghobrial, Xian C Li.
Int Immunol, 2013 Sep 13; 25(10). PMID: 24027199    Free PMC article.
Review.
CCR7 expression and intratumoral FOXP3+ regulatory T cells are correlated with overall survival and lymph node metastasis in gastric cancer.
Shuang Zhou, Zhenbing Shen, +13 authors, Chunmin Liang.
PLoS One, 2013 Sep 17; 8(9). PMID: 24040244    Free PMC article.
PC61 (anti-CD25) treatment inhibits influenza A virus-expanded regulatory T cells and severe lung pathology during a subsequent heterologous lymphocytic choriomeningitis virus infection.
Anke R M Kraft, Myriam F Wlodarczyk, Laurie L Kenney, Liisa K Selin.
J Virol, 2013 Sep 21; 87(23). PMID: 24049180    Free PMC article.
TRAF6 is essential for maintenance of regulatory T cells that suppress Th2 type autoimmunity.
Go Muto, Hitoshi Kotani, +8 authors, Akihiko Yoshimura.
PLoS One, 2013 Sep 24; 8(9). PMID: 24058613    Free PMC article.
Photodynamic therapy plus regulatory T-cell depletion produces immunity against a mouse tumour that expresses a self-antigen.
E Reginato, P Mroz, +3 authors, M R Hamblin.
Br J Cancer, 2013 Sep 26; 109(8). PMID: 24064977    Free PMC article.
Regulatory T cells and natural killer T cells for modulation of GVHD following allogeneic hematopoietic cell transplantation.
Dominik Schneidawind, Antonio Pierini, Robert S Negrin.
Blood, 2013 Sep 27; 122(18). PMID: 24068494    Free PMC article.
Review.
HTLV-1 bZIP factor induces inflammation through labile Foxp3 expression.
Nanae Yamamoto-Taguchi, Yorifumi Satou, +5 authors, Masao Matsuoka.
PLoS Pathog, 2013 Sep 27; 9(9). PMID: 24068936    Free PMC article.
Toll-like receptor 4 deficiency accelerates the development of insulin-deficient diabetes in non-obese diabetic mice.
Elke Gülden, Masaru Ihira, +4 authors, Volker Burkart.
PLoS One, 2013 Oct 03; 8(9). PMID: 24086519    Free PMC article.
Effect of chronic morphine administration on circulating T cell population dynamics in rhesus macaques.
William D Cornwell, Mark G Lewis, +2 authors, Thomas J Rogers.
J Neuroimmunol, 2013 Oct 05; 265(1-2). PMID: 24090653    Free PMC article.
Integrated enrichment analysis of variants and pathways in genome-wide association studies indicates central role for IL-2 signaling genes in type 1 diabetes, and cytokine signaling genes in Crohn's disease.
Peter Carbonetto, Matthew Stephens.
PLoS Genet, 2013 Oct 08; 9(10). PMID: 24098138    Free PMC article.
Adipose tissue immunity and cancer.
Victoria Catalán, Javier Gómez-Ambrosi, Amaia Rodríguez, Gema Frühbeck.
Front Physiol, 2013 Oct 10; 4. PMID: 24106481    Free PMC article.
Review.
CD8+ Treg cells suppress CD8+ T cell-responses by IL-10-dependent mechanism during H5N1 influenza virus infection.
Qiang Zou, Bing Wu, +5 authors, Bin Wang.
Eur J Immunol, 2013 Oct 12; 44(1). PMID: 24114149    Free PMC article.
Actin cytoskeletal defects in immunodeficiency.
Dale A Moulding, Julien Record, Dessislava Malinova, Adrian J Thrasher.
Immunol Rev, 2013 Oct 15; 256(1). PMID: 24117828    Free PMC article.
Review.
Modulation of T Cell Metabolism and Function through Calcium Signaling.
Kelley M Fracchia, Christine Y Pai, Craig M Walsh.
Front Immunol, 2013 Oct 18; 4. PMID: 24133495    Free PMC article.
Review.
CD4(+) CD25(high) forkhead box protein 3(+) regulatory T lymphocytes suppress interferon-γ and CD107 expression in CD4(+) and CD8(+) T cells from tuberculous pleural effusions.
L Geffner, J I Basile, +5 authors, S de la Barrera.
Clin Exp Immunol, 2013 Oct 19; 175(2). PMID: 24134738    Free PMC article.
Itch expression by Treg cells controls Th2 inflammatory responses.
Hyung-seung Jin, Yoon Park, Chris Elly, Yun-Cai Liu.
J Clin Invest, 2013 Oct 19; 123(11). PMID: 24135136    Free PMC article.
Chronic heat stress inhibits immune responses to H5N1 vaccination through regulating CD4⁺ CD25⁺ Foxp3⁺ Tregs.
Di Meng, Yanxin Hu, +3 authors, Ming Wang.
Biomed Res Int, 2013 Oct 24; 2013. PMID: 24151582    Free PMC article.
Thymic regulatory T cell development: role of signalling pathways and transcription factors.
Mark Engel, Tom Sidwell, +2 authors, Ashish Banerjee.
Clin Dev Immunol, 2013 Nov 05; 2013. PMID: 24187564    Free PMC article.
Review.
B cells are critical for autoimmune pathology in Scurfy mice.
Susanne Aschermann, Christian H K Lehmann, +3 authors, Falk Nimmerjahn.
Proc Natl Acad Sci U S A, 2013 Nov 07; 110(47). PMID: 24194550    Free PMC article.
The plasticity of human Treg and Th17 cells and its role in autoimmunity.
Markus Kleinewietfeld, David A Hafler.
Semin Immunol, 2013 Nov 12; 25(4). PMID: 24211039    Free PMC article.
Highly Cited. Review.
Immunity, inflammation and cancer: a leading role for adenosine.
Luca Antonioli, Corrado Blandizzi, Pál Pacher, György Haskó.
Nat Rev Cancer, 2013 Nov 15; 13(12). PMID: 24226193
Highly Cited. Review.
Assessing T-cell responses in anticancer immunotherapy: Dendritic cells or myeloid-derived suppressor cells?
David Escors, Therese Liechtenstein, +9 authors, Karine Breckpot.
Oncoimmunology, 2013 Nov 19; 2(10). PMID: 24244902    Free PMC article.
Review.
Role of plasmacytoid dendritic cells and inducible costimulator-positive regulatory T cells in the immunosuppression microenvironment of gastric cancer.
Xiao-Mei Huang, Xiao-Sun Liu, +9 authors, Ji-Ren Yu.
Cancer Sci, 2013 Nov 23; 105(2). PMID: 24261990    Free PMC article.
Subinfectious hepatitis C virus exposures suppress T cell responses against subsequent acute infection.
Su-Hyung Park, Naga Suresh Veerapu, +5 authors, Barbara Rehermann.
Nat Med, 2013 Nov 26; 19(12). PMID: 24270546    Free PMC article.
Role of childhood infection in the sequelae of H. pylori disease.
Paul R Harris, Lesley E Smythies, Phillip D Smith, Guillermo I Perez-Perez.
Gut Microbes, 2013 Nov 28; 4(6). PMID: 24275060    Free PMC article.
Review.
Diacylglycerol kinase ζ limits the generation of natural regulatory T cells.
Amanda M Schmidt, Tao Zou, +4 authors, Taku Kambayashi.
Sci Signal, 2013 Nov 28; 6(303). PMID: 24280042    Free PMC article.
The paradox role of regulatory T cells in ischemic stroke.
Xiaomeng Xu, Min Li, Yongjun Jiang.
ScientificWorldJournal, 2013 Nov 30; 2013. PMID: 24288462    Free PMC article.
Review.
LncRNA DQ786243 affects Treg related CREB and Foxp3 expression in Crohn's disease.
Yu Qi Qiao, Mei Lan Huang, +3 authors, Jun Shen.
J Biomed Sci, 2013 Dec 03; 20. PMID: 24289115    Free PMC article.
Regulatory T cells and B cells: implication on autoimmune diseases.
Ping Wang, Song Guo Zheng.
Int J Clin Exp Pathol, 2013 Dec 03; 6(12). PMID: 24294353    Free PMC article.
Review.
Assessment of regulatory T cells in childhood immune thrombocytopenic purpura.
Karina L M Mazzucco, Lauro M Junior, +8 authors, Paulo J C Marostica.
ISRN Hematol, 2013 Dec 04; 2013. PMID: 24298390    Free PMC article.
NF-κB control of T cell development.
Steve Gerondakis, Thomas S Fulford, Nicole L Messina, Raelene J Grumont.
Nat Immunol, 2013 Dec 20; 15(1). PMID: 24352326
Highly Cited. Review.
The metalloprotease ADAM12 regulates the effector function of human Th17 cells.
Angela X Zhou, Aimee El Hed, +2 authors, Derya Unutmaz.
PLoS One, 2013 Dec 24; 8(11). PMID: 24363794    Free PMC article.
Bach2 regulates homeostasis of Foxp3+ regulatory T cells and protects against fatal lung disease in mice.
Eui Ho Kim, David J Gasper, +3 authors, M Suresh.
J Immunol, 2013 Dec 25; 192(3). PMID: 24367030    Free PMC article.
TRAF3 regulates the effector function of regulatory T cells and humoral immune responses.
Jae-Hoon Chang, Hongbo Hu, +6 authors, Shao-Cong Sun.
J Exp Med, 2014 Jan 01; 211(1). PMID: 24378539    Free PMC article.
N-Ethyl-N-nitrosourea mutagenesis in the mouse provides strong genetic and in vivo evidence for the role of the Caspase Recruitment Domain (CARD) of CARD-MAGUK1 in T regulatory cell development.
Emma M Salisbury, Lihui Wang, +2 authors, Philip G Ashton-Rickardt.
Immunology, 2014 Jan 05; 141(3). PMID: 24383645    Free PMC article.
The interplay between regulatory T cells and metabolism in immune regulation.
Hu Zeng, Hongbo Chi.
Oncoimmunology, 2014 Jan 10; 2(11). PMID: 24404429    Free PMC article.
Review.
Challenges and developing solutions for increasing the benefits of IL-2 treatment in tumor therapy.
Denise Skrombolas, John G Frelinger.
Expert Rev Clin Immunol, 2014 Jan 15; 10(2). PMID: 24410537    Free PMC article.
Review.
Effects of dietary glutamine on the homeostasis of CD4+ T cells in mice with dextran sulfate sodium-induced acute colitis.
Yuan-Chin Hsiung, Jun-Jen Liu, +2 authors, Sung-Ling Yeh.
PLoS One, 2014 Jan 15; 9(1). PMID: 24416230    Free PMC article.
Protective and detrimental roles for regulatory T cells in a viral model for multiple sclerosis.
Nicholas E Martinez, Fridrik Karlsson, +5 authors, Ikuo Tsunoda.
Brain Pathol, 2014 Jan 15; 24(5). PMID: 24417588    Free PMC article.
Regulatory T cells as adjuvant target for enhancing the viral disease vaccine efficacy.
Jagadeesh Bayry.
Virusdisease, 2014 Jan 16; 25(1). PMID: 24426307    Free PMC article.
Review.
The multifaceted role of Th17 lymphocytes and their associated cytokines in cancer.
Darya Alizadeh, Emmanuel Katsanis, Nicolas Larmonier.
Clin Dev Immunol, 2014 Jan 24; 2013. PMID: 24454480    Free PMC article.
Review.
Th17 cells in immunity and autoimmunity.
Simone Kennedy Bedoya, Brandon Lam, Kenneth Lau, Joseph Larkin.
Clin Dev Immunol, 2014 Jan 24; 2013. PMID: 24454481    Free PMC article.
Highly Cited. Review.
Alterations in immune cell subsets and their cytokine secretion profile in childhood idiopathic thrombocytopenic purpura (ITP).
R M Talaat, A M Elmaghraby, S S Barakat, M El-Shahat.
Clin Exp Immunol, 2014 Jan 28; 176(2). PMID: 24460857    Free PMC article.
Diphtheria toxin-based bivalent human IL-2 fusion toxin with improved efficacy for targeting human CD25(+) cells.
Jaclyn Stromp Peraino, Huiping Zhang, +5 authors, Zhirui Wang.
J Immunol Methods, 2014 Jan 28; 405. PMID: 24462799    Free PMC article.
To drive or be driven: the path of a mouse model of recurrent pregnancy loss.
Elizabeth A Bonney, Stephen A Brown.
Reproduction, 2014 Jan 30; 147(5). PMID: 24472815    Free PMC article.
Review.
Hepatic expression of metallothionein I/II, glycoprotein 96, IL-6, and TGF- β in rat strains with different susceptibilities to experimental autoimmune encephalomyelitis.
Tanja Grubić-Kezele, Gordana Blagojević Zagorac, +3 authors, Biserka Radošević-Stašić.
Clin Dev Immunol, 2014 Feb 04; 2013. PMID: 24489578    Free PMC article.
Identification of STAT5A and STAT5B target genes in human T cells.
Takahiro Kanai, Scott Seki, +6 authors, Kari C Nadeau.
PLoS One, 2014 Feb 06; 9(1). PMID: 24497979    Free PMC article.
Prevention of allogeneic cardiac graft rejection by transfer of ex vivo expanded antigen-specific regulatory T-cells.
Fumika Takasato, Rimpei Morita, +5 authors, Akihiko Yoshimura.
PLoS One, 2014 Feb 06; 9(2). PMID: 24498362    Free PMC article.
Characterization of human CD39+ Th17 cells with suppressor activity and modulation in inflammatory bowel disease.
Maria Serena Longhi, Alan Moss, +5 authors, Simon C Robson.
PLoS One, 2014 Feb 08; 9(2). PMID: 24505337    Free PMC article.
Narrowband ultraviolet B phototherapy ameliorates acute graft-versus-host disease by a mechanism involving in vivo expansion of CD4+CD25+Foxp3+ regulatory T cells.
Satoshi Iyama, Kazuyuki Murase, +17 authors, Junji Kato.
Int J Hematol, 2014 Feb 22; 99(4). PMID: 24557710
Impaired circulating CD4+ LAP+ regulatory T cells in patients with acute coronary syndrome and its mechanistic study.
Zheng-Feng Zhu, Kai Meng, +10 authors, Qiu-Tang Zeng.
PLoS One, 2014 Feb 22; 9(2). PMID: 24558424    Free PMC article.
Th17 cells and Tregs: unlikely allies.
Xin Chen, Joost J Oppenheim.
J Leukoc Biol, 2014 Feb 25; 95(5). PMID: 24563509    Free PMC article.
Review.
Ultra low-dose IL-2 for GVHD prophylaxis after allogeneic hematopoietic stem cell transplantation mediates expansion of regulatory T cells without diminishing antiviral and antileukemic activity.
Alana A Kennedy-Nasser, Stephanie Ku, +16 authors, Catherine M Bollard.
Clin Cancer Res, 2014 Feb 28; 20(8). PMID: 24573552    Free PMC article.
Highly Cited.
Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression.
Martin Vaeth, Gerd Müller, +6 authors, Friederike Berberich-Siebelt.
J Exp Med, 2014 Mar 05; 211(3). PMID: 24590764    Free PMC article.
Highly Cited.
The degree of CD4+ T cell autoreactivity determines cellular pathways underlying inflammatory arthritis.
Olivia A Perng, Malinda Aitken, +5 authors, Andrew J Caton.
J Immunol, 2014 Mar 05; 192(7). PMID: 24591372    Free PMC article.
Th1 response and systemic treg deficiency in inclusion body myositis.
Yves Allenbach, Wahiba Chaara, +14 authors, Olivier Benveniste.
PLoS One, 2014 Mar 07; 9(3). PMID: 24594700    Free PMC article.
Dendritic cell-MHC class II and Itk regulate functional development of regulatory innate memory CD4+ T cells in bone marrow transplantation.
Weishan Huang, Qian Qi, +3 authors, Avery August.
J Immunol, 2014 Mar 13; 192(7). PMID: 24610010    Free PMC article.
Interindividual variation in human T regulatory cells.
Alessandra Ferraro, Anna Morena D'Alise, +10 authors, Christophe Benoist.
Proc Natl Acad Sci U S A, 2014 Mar 13; 111(12). PMID: 24610777    Free PMC article.
Impaired balance of T helper 17/T regulatory cells in carbon tetrachloride-induced liver fibrosis in mice.
Xiao-Fei Sun, Lei Gu, Wen-Sheng Deng, Qing Xu.
World J Gastroenterol, 2014 Mar 13; 20(8). PMID: 24616573    Free PMC article.
Advances in the cellular immunological pathogenesis of type 1 diabetes.
Min Li, Lu-Jun Song, Xin-Yu Qin.
J Cell Mol Med, 2014 Mar 19; 18(5). PMID: 24629100    Free PMC article.
Review.
Tumour immunogenicity, antigen presentation and immunological barriers in cancer immunotherapy.
David Escors.
New J Sci, 2014 Mar 19; 2014. PMID: 24634791    Free PMC article.
T cells and lung injury. Impact of rapamycin.
Takeshi Nakajima, Ko-Wei Lin, +4 authors, Patricia W Finn.
Am J Respir Cell Mol Biol, 2014 Mar 20; 51(2). PMID: 24641710    Free PMC article.
Regulatory T cells promote a protective Th17-associated immune response to intestinal bacterial infection with C. rodentium.
Z Wang, C Friedrich, +6 authors, M Lochner.
Mucosal Immunol, 2014 Mar 22; 7(6). PMID: 24646939
Tipping the balance in metabolic regulation: regulating regulatory T cells by costimulation.
Ling Qi.
Diabetes, 2014 Mar 22; 63(4). PMID: 24651799    Free PMC article.
Inhibition of calcineurin abrogates while inhibition of mTOR promotes regulatory T cell expansion and graft-versus-host disease protection by IL-2 in allogeneic bone marrow transplantation.
Atsushi Satake, Amanda M Schmidt, Shosaku Nomura, Taku Kambayashi.
PLoS One, 2014 Mar 25; 9(3). PMID: 24658577    Free PMC article.
Reduction of IL-17A might suppress the Th1 response and promote the Th2 response by boosting the function of Treg cells during silica-induced inflammatory response in vitro.
Wen Tang, Fangwei Liu, +5 authors, Jie Chen.
Mediators Inflamm, 2014 Apr 03; 2014. PMID: 24692850    Free PMC article.
Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation.
Hiromasa Morikawa, Naganari Ohkura, +11 authors, FANTOM Consortium.
Proc Natl Acad Sci U S A, 2014 Apr 08; 111(14). PMID: 24706905    Free PMC article.
Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection.
Shivani Srivastava, Meghan A Koch, Marion Pepper, Daniel J Campbell.
J Exp Med, 2014 Apr 09; 211(5). PMID: 24711580    Free PMC article.
Highly Cited.
CD4CD8αα lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease.
Guillaume Sarrabayrouse, Céline Bossard, +10 authors, Francine Jotereau.
PLoS Biol, 2014 Apr 10; 12(4). PMID: 24714093    Free PMC article.
Innate and adaptive immune interactions at the fetal-maternal interface in healthy human pregnancy and pre-eclampsia.
Peter Hsu, Ralph Kay Heinrich Nanan.
Front Immunol, 2014 Apr 16; 5. PMID: 24734032    Free PMC article.
Review.
CD3 antibody and IL-2 complex combination therapy inhibits atherosclerosis by augmenting a regulatory immune response.
Kazuyuki Kasahara, Naoto Sasaki, +5 authors, Ken-Ichi Hirata.
J Am Heart Assoc, 2014 Apr 24; 3(2). PMID: 24755152    Free PMC article.
A novel oxygen carrier "YQ23" suppresses the liver tumor metastasis by decreasing circulating endothelial progenitor cells and regulatory T cells.
Chang Xian Li, Bing L Wong, +12 authors, Kwan Man.
BMC Cancer, 2014 Apr 29; 14. PMID: 24766798    Free PMC article.
Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cells.
Florian Wirsdörfer, Federica Cappuccini, +5 authors, Verena Jendrossek.
Radiat Oncol, 2014 Apr 29; 9. PMID: 24766907    Free PMC article.
Cytotoxic T-Cells in Peripheral Blood in Women with Endometriosis.
N Slabe, H Meden-Vrtovec, +2 authors, A Ihan.
Geburtshilfe Frauenheilkd, 2014 Apr 29; 73(10). PMID: 24771894    Free PMC article.
Ubiquitous points of control over regulatory T cells.
Fan Pan, Joseph Barbi.
J Mol Med (Berl), 2014 Apr 30; 92(6). PMID: 24777637    Free PMC article.
Review.
Gut microbiota and the paradox of cancer immunotherapy.
Theofilos Poutahidis, Markus Kleinewietfeld, Susan E Erdman.
Front Immunol, 2014 Apr 30; 5. PMID: 24778636    Free PMC article.
Review.
GATA3: a master of many trades in immune regulation.
Yisong Y Wan.
Trends Immunol, 2014 May 03; 35(6). PMID: 24786134    Free PMC article.
Review.
Restoring the balance: immunotherapeutic combinations for autoimmune disease.
Dawn E Smilek, Mario R Ehlers, Gerald T Nepom.
Dis Model Mech, 2014 May 06; 7(5). PMID: 24795433    Free PMC article.
Review.
Distinct functions of specialized dendritic cell subsets in atherosclerosis and the road ahead.
Alma Zernecke.
Scientifica (Cairo), 2014 May 13; 2014. PMID: 24818041    Free PMC article.
Review.
Polymorphisms and plasma level of transforming growth factor-Beta 1 and risk for preeclampsia: a systematic review.
Xun Li, Lin Shen, Hongzhuan Tan.
PLoS One, 2014 May 16; 9(5). PMID: 24823830    Free PMC article.
Systematic Review.
Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes.
Michael Bonelli, Han-Yu Shih, +8 authors, John J O'Shea.
Curr Top Microbiol Immunol, 2014 May 17; 381. PMID: 24831346    Free PMC article.
Review.
The Biology of Autoimmune Response in the Scurfy Mice that Lack the CD4+Foxp3+ Regulatory T-Cells.
Shyr-Te Ju, Rahul Sharma, +2 authors, Shu Man Fu.
Biology (Basel), 2012 Jan 01; 1(1). PMID: 24832045    Free PMC article.
Gut microbiota-generated metabolites in animal health and disease.
Won-Jae Lee, Koji Hase.
Nat Chem Biol, 2014 May 20; 10(6). PMID: 24838170
Highly Cited. Review.
The regulation of inflammatory mediators in acute kidney injury via exogenous mesenchymal stem cells.
Tao Du, Ying-Jian Zhu.
Mediators Inflamm, 2014 May 20; 2014. PMID: 24839354    Free PMC article.
Review.
Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO.
Juan Liu, Chaofeng Han, +17 authors, Xuetao Cao.
Nat Immunol, 2014 May 27; 15(7). PMID: 24859449
'Default' generated neonatal regulatory T cells are hypomethylated at conserved non-coding sequence 2 and promote long-term cardiac allograft survival.
Chao Cheng, Sihua Wang, +7 authors, Jiahong Xia.
Immunology, 2014 Jun 20; 143(4). PMID: 24944101    Free PMC article.
Prediction of antiviral efficacy in patients with chronic hepatitis C by changes in forkhead box protein 3 levels.
Jia-Bao Chang, Rong Xue, +4 authors, Yong-Feng Yang.
Exp Ther Med, 2014 Jun 20; 8(1). PMID: 24944616    Free PMC article.
MeCP2 enforces Foxp3 expression to promote regulatory T cells' resilience to inflammation.
Chaoran Li, Shan Jiang, +5 authors, Qi-Jing Li.
Proc Natl Acad Sci U S A, 2014 Jun 25; 111(27). PMID: 24958888    Free PMC article.
Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease.
Masaki Miyazaki, Kazuko Miyazaki, +7 authors, Cornelis Murre.
Nat Immunol, 2014 Jun 30; 15(8). PMID: 24973820    Free PMC article.
PD-1 regulates extrathymic regulatory T-cell differentiation.
Xiufen Chen, Dominick Fosco, +4 authors, Justin Kline.
Eur J Immunol, 2014 Jul 01; 44(9). PMID: 24975127    Free PMC article.
TREG-cell therapies for autoimmune rheumatic diseases.
Makoto Miyara, Yoshinaga Ito, Shimon Sakaguchi.
Nat Rev Rheumatol, 2014 Jul 02; 10(9). PMID: 24980140
Highly Cited. Review.
Regulatory T cells protect fine particulate matter-induced inflammatory responses in human umbilical vein endothelial cells.
Wen-cai Zhang, Yan-ge Wang, +9 authors, Long-xian Cheng.
Mediators Inflamm, 2014 Jul 06; 2014. PMID: 24987196    Free PMC article.
Hormonal regulation of the immune microenvironment in the mammary gland.
Eleanor F Need, Vahid Atashgaran, Wendy V Ingman, Pallave Dasari.
J Mammary Gland Biol Neoplasia, 2014 Jul 06; 19(2). PMID: 24993978
Review.
Association of serum interleukin-27 with the exacerbation of chronic obstructive pulmonary disease.
Takashi Angata, Takeo Ishii, +5 authors, Naoyuki Taniguchi.
Physiol Rep, 2014 Jul 06; 2(7). PMID: 24994897    Free PMC article.
Immune biomarkers of anti-EGFR monoclonal antibody therapy.
S Trivedi, F Concha-Benavente, +4 authors, R L Ferris.
Ann Oncol, 2014 Jul 06; 26(1). PMID: 24997207    Free PMC article.
Review.
Special role of Foxp3 for the specifically altered microRNAs in Regulatory T cells of HCC patients.
Long Chen, Huiying Ma, +7 authors, Chunmin Liang.
BMC Cancer, 2014 Jul 09; 14. PMID: 25000974    Free PMC article.
Influence of maternal immunization with allergens on the thymic maturation of lymphocytes with regulatory potential in children: a broad field for further exploration.
Jefferson Russo Victor.
J Immunol Res, 2014 Jul 11; 2014. PMID: 25009823    Free PMC article.
Review.
Both positive and negative effects on immune responses by expression of a second class II MHC molecule.
Peggy P Ni, Yaming Wang, Paul M Allen.
Mol Immunol, 2014 Jul 14; 62(1). PMID: 25016574    Free PMC article.
Natural killer cells and regulatory T cells in early pregnancy loss.
Surendra Sharma.
Int J Dev Biol, 2014 Jul 16; 58(2-4). PMID: 25023688    Free PMC article.
Review.
Mechanisms of T-cell immunosuppression by mesenchymal stromal cells: what do we know so far?
Rodrigo Haddad, Felipe Saldanha-Araujo.
Biomed Res Int, 2014 Jul 16; 2014. PMID: 25025040    Free PMC article.
Review.
The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2.
Zuoan Yi, Wai Wai Lin, Laura L Stunz, Gail A Bishop.
Nat Immunol, 2014 Jul 17; 15(9). PMID: 25029551    Free PMC article.
Successful immunotherapy of autoimmune cholangitis by adoptive transfer of forkhead box protein 3(+) regulatory T cells.
H Tanaka, W Zhang, +10 authors, M E Gershwin.
Clin Exp Immunol, 2014 Jul 22; 178(2). PMID: 25041369    Free PMC article.
Rapid rebound of the Treg compartment in DEREG mice limits the impact of Treg depletion on mycobacterial burden, but prevents autoimmunity.
Luciana Berod, Philipp Stüve, +8 authors, Tim Sparwasser.
PLoS One, 2014 Jul 23; 9(7). PMID: 25050936    Free PMC article.
Regulatory T cells enhance mesenchymal stem cell survival and proliferation following autologous cotransplantation in ischemic myocardium.
Yifu Zhou, Avneesh K Singh, +7 authors, Keith A Horvath.
J Thorac Cardiovasc Surg, 2014 Jul 24; 148(3). PMID: 25052825    Free PMC article.
The immunopathology of ANCA-associated vasculitis.
Eoin F McKinney, Lisa C Willcocks, Verena Broecker, Kenneth G C Smith.
Semin Immunopathol, 2014 Jul 25; 36(4). PMID: 25056155    Free PMC article.
Review.
IL-2-inducible T cell kinase tunes T regulatory cell development and is required for suppressive function.
Weishan Huang, Ah-Reum Jeong, +2 authors, Avery August.
J Immunol, 2014 Jul 27; 193(5). PMID: 25063868    Free PMC article.
Regulatory T cells suppress CD4+ T cells through NFAT-dependent transcriptional mechanisms.
Daniel S Shin, Ayana Jordan, +5 authors, Fernando Macian.
EMBO Rep, 2014 Jul 31; 15(9). PMID: 25074018    Free PMC article.
Clinical significance of serum soluble T cell regulatory molecules in clear cell renal cell carcinoma.
Akinori Masuda, Kyoko Arai, +9 authors, Takao Kamai.
Biomed Res Int, 2014 Aug 05; 2014. PMID: 25089268    Free PMC article.
PIM1 kinase phosphorylates the human transcription factor FOXP3 at serine 422 to negatively regulate its activity under inflammation.
Zhiyuan Li, Fang Lin, +10 authors, Bin Li.
J Biol Chem, 2014 Aug 07; 289(39). PMID: 25096571    Free PMC article.
The integrative roles of chemokines at the maternal-fetal interface in early pregnancy.
Mei-Rong Du, Song-Cun Wang, Da-Jin Li.
Cell Mol Immunol, 2014 Aug 12; 11(5). PMID: 25109684    Free PMC article.
Review.
Cerebral ischemia increases bone marrow CD4+CD25+FoxP3+ regulatory T cells in mice via signals from sympathetic nervous system.
Jianping Wang, Lie Yu, +7 authors, Jian Wang.
Brain Behav Immun, 2014 Aug 12; 43. PMID: 25110149    Free PMC article.
Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection.
Pablo Penaloza-MacMaster, Alice O Kamphorst, +10 authors, Rafi Ahmed.
J Exp Med, 2014 Aug 13; 211(9). PMID: 25113973    Free PMC article.
Highly Cited.
Transcriptional and epigenetic networks of helper T and innate lymphoid cells.
Han-Yu Shih, Giuseppe Sciumè, +8 authors, John J O'Shea.
Immunol Rev, 2014 Aug 16; 261(1). PMID: 25123275    Free PMC article.
Review.
Complex interactions of transcription factors in mediating cytokine biology in T cells.
Peng Li, Rosanne Spolski, Wei Liao, Warren J Leonard.
Immunol Rev, 2014 Aug 16; 261(1). PMID: 25123282    Free PMC article.
Review.
Presence of FOXP3(+)Treg cells is correlated with colorectal cancer progression.
Zhengcai Liu, Qike Huang, +4 authors, Weizhong Wang.
Int J Clin Exp Med, 2014 Aug 16; 7(7). PMID: 25126180    Free PMC article.
Function of a Foxp3 cis-element in protecting regulatory T cell identity.
Xudong Li, Yuqiong Liang, +2 authors, Ye Zheng.
Cell, 2014 Aug 16; 158(4). PMID: 25126782    Free PMC article.
Highly Cited.
Regulatory T cells are recruited in the infarcted mouse myocardium and may modulate fibroblast phenotype and function.
Amit Saxena, Marcin Dobaczewski, +4 authors, Nikolaos G Frangogiannis.
Am J Physiol Heart Circ Physiol, 2014 Aug 17; 307(8). PMID: 25128167    Free PMC article.
A B-1a cell subset induces Foxp3(-) T cells with regulatory activity through an IL-10-independent pathway.
Ling-Hui Hsu, Kun-Po Li, Kuan-Hua Chu, Bor-Luen Chiang.
Cell Mol Immunol, 2014 Aug 19; 12(3). PMID: 25132452    Free PMC article.
SOCS1 and regulation of regulatory T cells plasticity.
Reiko Takahashi, Akihiko Yoshimura.
J Immunol Res, 2014 Aug 19; 2014. PMID: 25133199    Free PMC article.
Review.
Utilizing regulatory T cells against rheumatoid arthritis.
Mohammad Haque, Kristin Fino, +2 authors, Jianxun Song.
Front Oncol, 2014 Aug 26; 4. PMID: 25152867    Free PMC article.
Review.
TGFβ in T cell biology and tumor immunity: Angel or devil?
Eric Tu, Pei Zhi Cheryl Chia, Wanjun Chen.
Cytokine Growth Factor Rev, 2014 Aug 27; 25(4). PMID: 25156420    Free PMC article.
Review.
Targeting α- and β-Adrenergic Receptors Differentially Shifts Th1, Th2, and Inflammatory Cytokine Profiles in Immune Organs to Attenuate Adjuvant Arthritis.
Cheri L Lubahn, Dianne Lorton, +2 authors, Denise L Bellinger.
Front Immunol, 2014 Aug 27; 5. PMID: 25157248    Free PMC article.
The injury-induced myokine insulin-like 6 is protective in experimental autoimmune myositis.
Ling Zeng, Sonomi Maruyama, +6 authors, Kenneth Walsh.
Skelet Muscle, 2014 Aug 28; 4. PMID: 25161767    Free PMC article.
Anti-inflammatory effects of recombinant human PDCD5 (rhPDCD5) in a rat collagen-induced model of arthritis.
Juan Xiao, Ge Li, +3 authors, Yingyu Chen.
Inflammation, 2014 Sep 03; 38(1). PMID: 25178696    Free PMC article.
Epigenetic enzymes are the therapeutic targets for CD4(+)CD25(+/high)Foxp3(+) regulatory T cells.
Jahaira Lopez-Pastrana, Ying Shao, +2 authors, Xiao-Feng Yang.
Transl Res, 2014 Sep 07; 165(1). PMID: 25193380    Free PMC article.
Review.
CD45 ligation expands Tregs by promoting interactions with DCs.
Geoffrey Camirand, Ying Wang, +12 authors, David M Rothstein.
J Clin Invest, 2014 Sep 10; 124(10). PMID: 25202978    Free PMC article.
Increase in the expression of CD4 + CD25+ lymphocytic T cells in the indeterminate clinical form of human Chagas disease after stimulation with recombinant antigens of Trypanosoma cruzi.
Suellen Carvalho de Moura Braz, Adriene Siqueira de Melo, +6 authors, Yara de Miranda Gomes.
J Clin Immunol, 2014 Sep 11; 34(8). PMID: 25205548
Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4.
Hye Sun Kuehn, Weiming Ouyang, +33 authors, Gulbu Uzel.
Science, 2014 Sep 13; 345(6204). PMID: 25213377    Free PMC article.
Highly Cited.
Synthesis of novel tylophorine derivatives and evaluation of their anti-inflammatory activity.
Ti Wen, Ziwen Wang, +8 authors, Qingmin Wang.
ACS Med Chem Lett, 2014 Sep 16; 5(9). PMID: 25221661    Free PMC article.
Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth.
Yuan Yin, Xing Cai, +19 authors, Chen-Yu Zhang.
Cell Res, 2014 Sep 17; 24(10). PMID: 25223704    Free PMC article.
Highly Cited.
Neuropilin-1+ regulatory T cells promote skin allograft survival and modulate effector CD4+ T cells phenotypic signature.
Mauricio Campos-Mora, Rodrigo A Morales, +5 authors, Karina Pino-Lagos.
Immunol Cell Biol, 2014 Sep 24; 93(2). PMID: 25245111
The transcriptional repressor Bcl6 controls the stability of regulatory T cells by intrinsic and extrinsic pathways.
Deepali V Sawant, Hao Wu, +3 authors, Alexander L Dent.
Immunology, 2014 Sep 30; 145(1). PMID: 25262912    Free PMC article.
Helminth parasites alter protection against Plasmodium infection.
Víctor H Salazar-Castañon, Martha Legorreta-Herrera, Miriam Rodriguez-Sosa.
Biomed Res Int, 2014 Oct 03; 2014. PMID: 25276830    Free PMC article.
Review.
Suppressive oligodeoxynucleotides promote the generation of regulatory T cells by inhibiting STAT1 phosphorylation.
Christian Bode, Jing Wang, Dennis M Klinman.
Int Immunopharmacol, 2014 Oct 15; 23(2). PMID: 25311665    Free PMC article.
Regulatory T cells in central nervous system injury: a double-edged sword.
James T Walsh, Jingjing Zheng, +3 authors, Jonathan Kipnis.
J Immunol, 2014 Oct 17; 193(10). PMID: 25320276    Free PMC article.
ImmuCo: a database of gene co-expression in immune cells.
Pingzhang Wang, Huiying Qi, +4 authors, Dalong Ma.
Nucleic Acids Res, 2014 Oct 19; 43(Database issue). PMID: 25326331    Free PMC article.
Functional improvement of regulatory T cells from rheumatoid arthritis subjects induced by capsular polysaccharide glucuronoxylomannogalactan.
Eva Pericolini, Elena Gabrielli, +7 authors, Anna Vecchiarelli.
PLoS One, 2014 Oct 23; 9(10). PMID: 25338013    Free PMC article.
Interleukin 2 in the pathogenesis and therapy of type 1 diabetes.
Michelle Rosenzwajg, Guillaume Churlaud, Agnès Hartemann, David Klatzmann.
Curr Diab Rep, 2014 Oct 27; 14(12). PMID: 25344788
Review.
The role of T and B cells in human atherosclerosis and atherothrombosis.
E Ammirati, F Moroni, M Magnoni, P G Camici.
Clin Exp Immunol, 2014 Oct 30; 179(2). PMID: 25352024    Free PMC article.
Review.
Skewed T-helper (Th)1/2- and Th17/T regulatory‑cell balances in patients with renal cell carcinoma.
Long Li, Cheng Yang, +6 authors, Ruiming Rong.
Mol Med Rep, 2014 Oct 30; 11(2). PMID: 25352158    Free PMC article.
The Regulation of CD4(+) T Cell Responses during Protozoan Infections.
Christian R Engwerda, Susanna S Ng, Patrick T Bunn.
Front Immunol, 2014 Oct 30; 5. PMID: 25352846    Free PMC article.
Review.
CD28-CD80 interactions control regulatory T cell motility and immunological synapse formation.
Timothy J Thauland, Yoshinobu Koguchi, Michael L Dustin, David C Parker.
J Immunol, 2014 Oct 31; 193(12). PMID: 25355918    Free PMC article.
Induction of macrophage-like immunosuppressive cells from mouse ES cells that contribute to prolong allogeneic graft survival.
Hiroya Kudo, Haruka Wada, +6 authors, Ken-ichiro Seino.
PLoS One, 2014 Oct 31; 9(10). PMID: 25356669    Free PMC article.
Regulatory T cells in B cell follicles.
Jae-Hoon Chang, Yeonseok Chung.
Immune Netw, 2014 Nov 02; 14(5). PMID: 25360073    Free PMC article.
Review.
The ratio of circulating regulatory T cells (Tregs)/Th17 cells is associated with acute allograft rejection in liver transplantation.
Ying Wang, Min Zhang, +7 authors, Ming Shi.
PLoS One, 2014 Nov 06; 9(11). PMID: 25372875    Free PMC article.
IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells.
Xin Chen, Jami Willette-Brown, +4 authors, Joost J Oppenheim.
FASEB J, 2014 Nov 08; 29(2). PMID: 25376833    Free PMC article.
Complement protein C1q bound to apoptotic cells suppresses human macrophage and dendritic cell-mediated Th17 and Th1 T cell subset proliferation.
Elizabeth V Clarke, Brian M Weist, Craig M Walsh, Andrea J Tenner.
J Leukoc Biol, 2014 Nov 09; 97(1). PMID: 25381385    Free PMC article.
Signatures of tumour immunity distinguish Asian and non-Asian gastric adenocarcinomas.
Suling J Lin, Johann A Gagnon-Bartsch, +28 authors, Patrick Tan.
Gut, 2014 Nov 12; 64(11). PMID: 25385008    Free PMC article.
Highly Cited.
Intravenous immunoglobulin exerts reciprocal regulation of Th1/Th17 cells and regulatory T cells in Guillain-Barré syndrome patients.
Mohan S Maddur, Magalie Rabin, +6 authors, Srini V Kaveri.
Immunol Res, 2014 Nov 14; 60(2-3). PMID: 25391612
Visualisation of the T cell differentiation programme by Canonical Correspondence Analysis of transcriptomes.
Masahiro Ono, Reiko J Tanaka, Manabu Kano.
BMC Genomics, 2014 Nov 28; 15. PMID: 25428805    Free PMC article.
Targeting CD44 augments the efficacy of Tregs in autoimmune diabetes.
Cheng-Rui Li, Erin E Mueller, Linda M Bradley.
Immunol Lett, 2014 Dec 03; 163(2). PMID: 25447401    Free PMC article.
Local delivery of mesenchymal stem cells with poly-lactic-co-glycolic acid nano-fiber scaffold suppress arthritis in rats.
Xiangmei Zhang, Kunihiro Yamaoka, +10 authors, Yoshiya Tanaka.
PLoS One, 2014 Dec 05; 9(12). PMID: 25474102    Free PMC article.
Bee venom phospholipase A2 protects against acetaminophen-induced acute liver injury by modulating regulatory T cells and IL-10 in mice.
Hyunseong Kim, Dong June Keum, +2 authors, Hyunsu Bae.
PLoS One, 2014 Dec 06; 9(12). PMID: 25478691    Free PMC article.
Treg identity protection by an epigenetic switch.
Xudong Li, Ye Zheng.
Cell Cycle, 2014 Dec 09; 13(20). PMID: 25485491    Free PMC article.
The signaling symphony: T cell receptor tunes cytokine-mediated T cell differentiation.
Weishan Huang, Avery August.
J Leukoc Biol, 2014 Dec 20; 97(3). PMID: 25525115    Free PMC article.
Review.
Development of Gene Transfer for Induction of Antigen-specific Tolerance.
Brandon K Sack, Roland W Herzog, Cox Terhorst, David M Markusic.
Mol Ther Methods Clin Dev, 2015 Jan 06; 1. PMID: 25558460    Free PMC article.
DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions.
Yongheng Chen, Chunxia Chen, +9 authors, Lin Chen.
Nucleic Acids Res, 2015 Jan 09; 43(2). PMID: 25567984    Free PMC article.
Molecules Great and Small: The Complement System.
Douglas R Mathern, Peter S Heeger.
Clin J Am Soc Nephrol, 2015 Jan 09; 10(9). PMID: 25568220    Free PMC article.
Highly Cited. Review.
The second touch hypothesis: T cell activation, homing and polarization.
Klaus Ley.
F1000Res, 2015 Jan 13; 3. PMID: 25580220    Free PMC article.
Dental pulp stem cells suppress the proliferation of lymphocytes via transforming growth factor-β1.
Gang Ding, Jianyi Niu, Yi Liu.
Hum Cell, 2015 Jan 22; 28(2). PMID: 25605036
Regulatory T cells and control of the germinal centre response.
Ine Vanderleyden, Michelle A Linterman, Kenneth G C Smith.
Arthritis Res Ther, 2015 Jan 22; 16(5). PMID: 25606598    Free PMC article.
Review.
GP96 is a GARP chaperone and controls regulatory T cell functions.
Yongliang Zhang, Bill X Wu, +9 authors, Zihai Li.
J Clin Invest, 2015 Jan 22; 125(2). PMID: 25607841    Free PMC article.
FOXP3+ Tregs: heterogeneous phenotypes and conflicting impacts on survival outcomes in patients with colorectal cancer.
Changhua Zhuo, Ye Xu, +5 authors, Bin Li.
Immunol Res, 2015 Jan 23; 61(3). PMID: 25608795
Review.
Generation of Regulatory T Cells to Antigen Expressed in the Retina.
Scott W McPherson, Neal D Heuss, Ute Lehman, Dale S Gregerson.
Curr Immunol Rev, 2011 Jan 01; 7(3). PMID: 25620898    Free PMC article.
Diabetes tolerogenic vaccines targeting antigen-specific inflammation.
Shuang Geng, Huiyuan Zhang, +10 authors, Bin Wang.
Hum Vaccin Immunother, 2015 Jan 27; 11(2). PMID: 25622092    Free PMC article.
Review.
Expression of interleukin-9 and its upstream stimulating factors in rats with ischemic stroke.
Yinyao Lin, Lei Zhang, +5 authors, Zhengqi Lu.
Neurol Sci, 2015 Feb 06; 36(6). PMID: 25652434
Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming.
Melanie P Matheu, Shivashankar Othy, +7 authors, Michael D Cahalan.
Nat Commun, 2015 Feb 06; 6. PMID: 25653051    Free PMC article.
Sleep disorders and increased risk of autoimmune diseases in individuals without sleep apnea.
Yi-Han Hsiao, Yung-Tai Chen, +9 authors, Kun-Ta Chou.
Sleep, 2015 Feb 12; 38(4). PMID: 25669189    Free PMC article.
Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis.
Raphael Sanches Peres, Foo Y Liew, +19 authors, Fernando Q Cunha.
Proc Natl Acad Sci U S A, 2015 Feb 13; 112(8). PMID: 25675517    Free PMC article.
[Regulatory T cells and rheumatic diseases].
J Y Humrich, T Kamradt, G Riemekasten.
Z Rheumatol, 2015 Feb 14; 74(1). PMID: 25676125
Review.
Vaccination to modulate atherosclerosis.
Takayuki Kimura, Kevin Tse, Alessandro Sette, Klaus Ley.
Autoimmunity, 2015 Feb 17; 48(3). PMID: 25683179    Free PMC article.
Review.
Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo.
Huey-Wen Hsiao, Tzu-Sheng Hsu, +5 authors, Ming-Zong Lai.
Nat Commun, 2015 Feb 20; 6. PMID: 25695215    Free PMC article.
Systems biologic analysis of T regulatory cells genetic pathways in murine primary biliary cirrhosis.
Yin-Hu Wang, Wei Yang, +5 authors, Zhe-Xiong Lian.
J Autoimmun, 2015 Feb 24; 59. PMID: 25701076    Free PMC article.
Association of colonic regulatory T cells with hepatitis C virus pathogenesis and liver pathology.
Helal F Hetta, Mohamed A Mekky, +8 authors, Mohamed Tarek M Shata.
J Gastroenterol Hepatol, 2015 Feb 25; 30(10). PMID: 25708446    Free PMC article.
Graft versus host disease: New insights into A2A receptor agonist therapy.
Karlie R Jones, Elizabeth M Kang.
Comput Struct Biotechnol J, 2015 Feb 25; 13. PMID: 25709759    Free PMC article.
Review.
Retina-specific T regulatory cells bring about resolution and maintain remission of autoimmune uveitis.
Phyllis B Silver, Phyllis Silver, +6 authors, Rachel R Caspi.
J Immunol, 2015 Feb 27; 194(7). PMID: 25716996    Free PMC article.
Generation, cryopreservation, function and in vivo persistence of ex vivo expanded cynomolgus monkey regulatory T cells.
Hao Guo, Hong Zhang, +2 authors, Angus W Thomson.
Cell Immunol, 2015 Mar 04; 295(1). PMID: 25732601    Free PMC article.
Immune approaches to the treatment of breast cancer, around the corner?
Carmen Criscitiello, Angela Esposito, +6 authors, Giuseppe Curigliano.
Breast Cancer Res, 2014 Jan 01; 16(1). PMID: 25774617    Free PMC article.
Review.
Distinct modes of antigen presentation promote the formation, differentiation, and activity of foxp3+ regulatory T cells in vivo.
Katherine A Weissler, Victoria Garcia, +5 authors, Andrew J Caton.
J Immunol, 2015 Mar 18; 194(8). PMID: 25780041    Free PMC article.
Cellular imaging in rheumatic diseases.
Robert A Benson, Iain B McInnes, James M Brewer, Paul Garside.
Nat Rev Rheumatol, 2015 Mar 25; 11(6). PMID: 25800215
Review.
Engraftment of embryonic stem cells and differentiated progeny by host conditioning with total lymphoid irradiation and regulatory T cells.
Yuqiong Pan, Dennis B Leveson-Gower, +8 authors, Robert S Negrin.
Cell Rep, 2015 Mar 25; 10(11). PMID: 25801020    Free PMC article.
Regulatory T cells in human and angiotensin II-induced mouse abdominal aortic aneurysms.
Yi Zhou, Wenxue Wu, +4 authors, Guo-Ping Shi.
Cardiovasc Res, 2015 Apr 01; 107(1). PMID: 25824145    Free PMC article.
Impact of dietary components on NK and Treg cell function for cancer prevention.
Young S Kim, Thomas J Sayers, +2 authors, Howard A Young.
Mol Carcinog, 2015 Apr 08; 54(9). PMID: 25845339    Free PMC article.
Review.
Immunosuppression in early postnatal days induces persistent and allergen-specific immune tolerance to asthma in adult mice.
Yan Chen, Jin Zhang, Yong Lu, Libo Wang.
PLoS One, 2015 Apr 11; 10(4). PMID: 25860995    Free PMC article.
Peripheral mononuclear blood cells contribute to the obesity-associated inflammatory state independently of glycemic status: involvement of the novel proinflammatory adipokines chemerin, chitinase-3-like protein 1, lipocalin-2 and osteopontin.
Victoria Catalán, Javier Gómez-Ambrosi, +6 authors, Gema Frühbeck.
Genes Nutr, 2015 Apr 15; 10(3). PMID: 25869413    Free PMC article.
Myeloid lineage skewing due to exacerbated NF-κB signaling facilitates osteopenia in Scurfy mice.
T H-P Chen, G Swarnkar, G Mbalaviele, Y Abu-Amer.
Cell Death Dis, 2015 Apr 17; 6. PMID: 25880090    Free PMC article.
Role of regulatory T cell in clinical outcome of traumatic brain injury.
Min Li, Yun-Peng Lin, +3 authors, Jian-Ning Zhang.
Chin Med J (Engl), 2015 Apr 18; 128(8). PMID: 25881602    Free PMC article.
Therapeutic efficacy and biodistribution of allogeneic mesenchymal stem cells delivered by intrasplenic and intrapancreatic routes in streptozotocin-induced diabetic mice.
Juliana Navarro Ueda Yaochite, Carolina Caliari-Oliveira, +6 authors, Eduardo Antônio Donadi.
Stem Cell Res Ther, 2015 Apr 18; 6. PMID: 25884215    Free PMC article.
Survival and maintenance of regulatory T cells require the kinase TAK1.
Jae-Hoon Chang, Hongbo Hu, Shao-Cong Sun.
Cell Mol Immunol, 2015 Apr 22; 12(5). PMID: 25891214    Free PMC article.
Altered connexin 43 expression underlies age-dependent decrease of regulatory T cell suppressor function in nonobese diabetic mice.
Michal Kuczma, Cong-Yi Wang, +2 authors, Piotr Kraj.
J Immunol, 2015 Apr 26; 194(11). PMID: 25911751    Free PMC article.
Targeting the innate immune system as immunotherapy for acute myeloid leukemia.
Emily Curran, Leticia Corrales, Justin Kline.
Front Oncol, 2015 Apr 29; 5. PMID: 25914882    Free PMC article.
Review.
Three-Dimensional Gradients of Cytokine Signaling between T Cells.
Kevin Thurley, Daniel Gerecht, Elfriede Friedmann, Thomas Höfer.
PLoS Comput Biol, 2015 Apr 30; 11(4). PMID: 25923703    Free PMC article.
Human and Mouse CD8(+)CD25(+)FOXP3(+) Regulatory T Cells at Steady State and during Interleukin-2 Therapy.
Guillaume Churlaud, Fabien Pitoiset, +4 authors, David Klatzmann.
Front Immunol, 2015 May 01; 6. PMID: 25926835    Free PMC article.
Highly Cited.
Violacein Treatment Modulates Acute and Chronic Inflammation through the Suppression of Cytokine Production and Induction of Regulatory T Cells.
Liana Verinaud, Stefanie Costa Pinto Lopes, +13 authors, Rodolfo Thomé.
PLoS One, 2015 May 06; 10(5). PMID: 25938431    Free PMC article.
Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets.
Stephanie Flaherty, Joseph M Reynolds.
J Vis Exp, 2015 May 06; (98). PMID: 25938923    Free PMC article.
A breakthrough in probiotics: Clostridium butyricum regulates gut homeostasis and anti-inflammatory response in inflammatory bowel disease.
Takanori Kanai, Yohei Mikami, Atsushi Hayashi.
J Gastroenterol, 2015 May 06; 50(9). PMID: 25940150
Review.
Differential potency of regulatory T cell-mediated immunosuppression in kidney tumors compared to subcutaneous tumors.
Christel Devaud, Jennifer A Westwood, +6 authors, Michael H Kershaw.
Oncoimmunology, 2015 May 06; 3(11). PMID: 25941590    Free PMC article.
T regulatory cells: Achilles' heel of Mycobacterium tuberculosis infection?
Om Parkash, Sonali Agrawal, M Madhan Kumar.
Immunol Res, 2015 May 08; 62(3). PMID: 25948475
Review.
An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells.
Ivana Campia, Ilaria Buondonno, +5 authors, Chiara Riganti.
PLoS One, 2015 May 09; 10(5). PMID: 25955018    Free PMC article.
BTLA associates with increased Foxp3 expression in CD4(+) T cells in dextran sulfate sodium-induced colitis.
Han-Xian Zhang, Bin Zhu, +9 authors, Jun-Fa Xu.
Int J Clin Exp Pathol, 2015 May 15; 8(2). PMID: 25973010    Free PMC article.
Paracrine co-delivery of TGF-β and IL-2 using CD4-targeted nanoparticles for induction and maintenance of regulatory T cells.
Michael D McHugh, Jason Park, +3 authors, Tarek M Fahmy.
Biomaterials, 2015 May 15; 59. PMID: 25974747    Free PMC article.
Wnt signaling in dendritic cells: its role in regulation of immunity and tolerance.
Daniel Swafford, Santhakumar Manicassamy.
Discov Med, 2015 May 16; 19(105). PMID: 25977193    Free PMC article.
Review.
Regulatory T cell identity: formation and maintenance.
Xudong Li, Ye Zheng.
Trends Immunol, 2015 May 20; 36(6). PMID: 25981968    Free PMC article.
Highly Cited. Review.
Design strategies and applications of circulating cell-mediated drug delivery systems.
Yixue Su, Zhiwei Xie, +2 authors, Jian Yang.
ACS Biomater Sci Eng, 2015 May 20; 1(4). PMID: 25984572    Free PMC article.
ImmuSort, a database on gene plasticity and electronic sorting for immune cells.
Pingzhang Wang, Yehong Yang, Wenling Han, Dalong Ma.
Sci Rep, 2015 May 20; 5. PMID: 25988315    Free PMC article.
Expanding regulatory T cells alleviates chikungunya virus-induced pathology in mice.
Wendy W L Lee, Teck-Hui Teo, +6 authors, Lisa F P Ng.
J Virol, 2015 May 23; 89(15). PMID: 25995249    Free PMC article.
Therapeutic window of interleukin-2 for autoimmune diseases.
Qizhi Tang.
Diabetes, 2015 May 23; 64(6). PMID: 25999537    Free PMC article.
Expression pattern of transcription factors and intracellular cytokines reveals that clinically cured tuberculosis is accompanied by an increase in Mycobacterium-specific Th1, Th2, and Th17 cells.
Marcos V da Silva, Vladimir J Massaro Junior, +5 authors, Virmondes Rodrigues.
Biomed Res Int, 2015 May 23; 2015. PMID: 26000298    Free PMC article.
An IL-27/Lag3 axis enhances Foxp3+ regulatory T cell-suppressive function and therapeutic efficacy.
J-S Do, A Visperas, +10 authors, B Min.
Mucosal Immunol, 2015 May 28; 9(1). PMID: 26013006    Free PMC article.
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3high regulatory T cells in humans.
Makoto Miyara, Driss Chader, +14 authors, Guy Gorochov.
Proc Natl Acad Sci U S A, 2015 May 28; 112(23). PMID: 26015572    Free PMC article.
Highly Cited.
Beyond adjuvants: immunomodulation strategies to enhance T cell immunity.
Alice O Kamphorst, Koichi Araki, Rafi Ahmed.
Vaccine, 2015 May 30; 33 Suppl 2. PMID: 26022562    Free PMC article.
Review.
Inflammation negatively regulates FOXP3 and regulatory T-cell function via DBC1.
Yayi Gao, Jiayou Tang, +15 authors, Bin Li.
Proc Natl Acad Sci U S A, 2015 Jun 11; 112(25). PMID: 26060310    Free PMC article.
T-cell mediated anti-tumor immunity after photodynamic therapy: why does it not always work and how can we improve it?
Florian Anzengruber, Pinar Avci, Lucas Freitas de Freitas, Michael R Hamblin.
Photochem Photobiol Sci, 2015 Jun 13; 14(8). PMID: 26062987    Free PMC article.
Androgen receptor modulates Foxp3 expression in CD4+CD25+Foxp3+ regulatory T-cells.
Magdalena Walecki, Florian Eisel, +6 authors, Monika Fijak.
Mol Biol Cell, 2015 Jun 13; 26(15). PMID: 26063731    Free PMC article.
FOXP3(+)Treg/Th17 cell imbalance in lung tissues of mice with asthma.
Hua Jiang, Xianbo Wu, +3 authors, Yuji Jiang.
Int J Clin Exp Med, 2015 Jun 13; 8(3). PMID: 26064325    Free PMC article.
Leucine-Rich Repeat Kinase 2 (Lrrk2) Deficiency Diminishes the Development of Experimental Autoimmune Uveitis (EAU) and the Adaptive Immune Response.
Wambui S Wandu, Cuiyan Tan, +8 authors, Igal Gery.
PLoS One, 2015 Jun 13; 10(6). PMID: 26067490    Free PMC article.
Tolerance Induction in Liver.
M H Karimi, B Geramizadeh, S A Malek-Hosseini.
Int J Organ Transplant Med, 2015 Jun 18; 6(2). PMID: 26082828    Free PMC article.
Review.
Ubiquitin-dependent regulation of Foxp3 and Treg function.
Joseph Barbi, Drew M Pardoll, Fan Pan.
Immunol Rev, 2015 Jun 19; 266(1). PMID: 26085205    Free PMC article.
Review.
The Novel PKCθ from Benchtop to Clinic.
Rouba Hage-Sleiman, Asmaa B Hamze, +2 authors, Ghassan Dbaibo.
J Immunol Res, 2015 Jun 20; 2015. PMID: 26090489    Free PMC article.
Review.
Regulatory T Cells in Autoimmune and Viral Chronic Hepatitis.
Pascal Lapierre, Alain Lamarre.
J Immunol Res, 2015 Jun 25; 2015. PMID: 26106627    Free PMC article.
Review.
Examining the Effects of External or Internal Radiation Exposure of Juvenile Mice on Late Morbidity after Infection with Influenza A.
Ravi S Misra, Carl J Johnston, +8 authors, Jacqueline P Williams.
Radiat Res, 2015 Jun 27; 184(1). PMID: 26114328    Free PMC article.
Role of CD4+ Foxp3+ Regulatory T Cells in Protection Induced by a Live Attenuated, Replicating Type I Vaccine Strain of Toxoplasma gondii.
Haroon Akbar, Isabelle Dimier-Poisson, Nathalie Moiré.
Infect Immun, 2015 Jul 01; 83(9). PMID: 26123802    Free PMC article.
Association of CD4(+)CD25(+)FoxP3(+) regulatory T cells with natural course of childhood chronic immune thrombocytopenic purpura.
Bo Ra Son, Ji Yoon Kim.
Korean J Pediatr, 2015 Jul 01; 58(5). PMID: 26124848    Free PMC article.
New insights into the mechanisms of Treg function.
David M Rothstein, Geoffrey Camirand.
Curr Opin Organ Transplant, 2015 Jul 01; 20(4). PMID: 26126193    Free PMC article.
Review.
An Act of Balance Between Adaptive and Maladaptive Immunity in Depression: a Role for T Lymphocytes.
Catherine Toben, Bernhard T Baune.
J Neuroimmune Pharmacol, 2015 Jul 03; 10(4). PMID: 26133121
Review.
Paclitaxel and Its Evolving Role in the Management of Ovarian Cancer.
Nirmala Chandralega Kampan, Mutsa Tatenda Madondo, +2 authors, Magdalena Plebanski.
Biomed Res Int, 2015 Jul 03; 2015. PMID: 26137480    Free PMC article.
Review.
Spontaneous Intestinal Tumorigenesis in Apc (/Min+) Mice Requires Altered T Cell Development with IL-17A.
Wook-Jin Chae, Alfred L M Bothwell.
J Immunol Res, 2015 Jul 07; 2015. PMID: 26146642    Free PMC article.
The Macrophage Galactose-Type C-Type Lectin (MGL) Modulates Regulatory T Cell Functions.
Ilaria Grazia Zizzari, Paola Martufi, +6 authors, Chiara Napoletano.
PLoS One, 2015 Jul 07; 10(7). PMID: 26147970    Free PMC article.
Transcription factor IRF8 controls Th1-like regulatory T-cell function.
Wonyong Lee, Hyeong Su Kim, Song Yi Baek, Gap Ryol Lee.
Cell Mol Immunol, 2015 Jul 15; 13(6). PMID: 26166768    Free PMC article.
In vitro and in vivo antitumor effects of 50 to 100-KDa components from B16 melanoma culture supernatant.
Ying-Song Qin, X U Zhang, Xiang-Yu Zhang.
Oncol Lett, 2015 Jul 15; 10(1). PMID: 26170991    Free PMC article.
Genome-wide Analysis of Host-Plasmodium yoelii Interactions Reveals Regulators of the Type I Interferon Response.
Jian Wu, Baowei Cai, +14 authors, Xin-Zhuan Su.
Cell Rep, 2015 Jul 21; 12(4). PMID: 26190101    Free PMC article.
The life (and death) of CD4+ CD28(null) T cells in inflammatory diseases.
Ingrid E Dumitriu.
Immunology, 2015 Jul 21; 146(2). PMID: 26190355    Free PMC article.
Review.
Repeated Injections of IL-2 Break Renal Allograft Tolerance Induced via Mixed Hematopoietic Chimerism in Monkeys.
Y Yamada, O Nadazdin, +8 authors, G Benichou.
Am J Transplant, 2015 Jul 21; 15(12). PMID: 26190648    Free PMC article.
Integrin αE(CD103) Is Involved in Regulatory T-Cell Function in Allergic Contact Hypersensitivity.
Andrea Braun, Nadin Dewert, +10 authors, Michael P Schön.
J Invest Dermatol, 2015 Jul 24; 135(12). PMID: 26203637
The past, present and future of immunotherapy against tumor.
Tao Jiang, Caicun Zhou.
Transl Lung Cancer Res, 2015 Jul 25; 4(3). PMID: 26207213    Free PMC article.
Review.
CD4+VEGFR1(HIGH) T cell as a novel Treg subset regulates inflammatory bowel disease in lymphopenic mice.
Jin-Young Shin, Il-Hee Yoon, +8 authors, Chung-Gyu Park.
Cell Mol Immunol, 2015 Jul 28; 12(5). PMID: 26211666    Free PMC article.
Thyroid dysfunction: an autoimmune aspect.
Farah Aziz Khan, Noura Al-Jameil, +2 authors, Hajera Tabassum.
Int J Clin Exp Med, 2015 Jul 30; 8(5). PMID: 26221205    Free PMC article.
Review.
Interleukin-2 administration after modified radical mastectomy in breast cancer therapy increases peripheral regulatory T cells.
Yunli Li, Lei Zhou, +4 authors, Wen Ouyang.
Int J Clin Exp Med, 2015 Jul 30; 8(5). PMID: 26221334    Free PMC article.
Role of Regulatory T Cells (Treg) and the Treg Effector Molecule Fibrinogen-like Protein 2 in Alloimmunity and Autoimmunity.
Andrzej Chruscinski, Hassan Sadozai, +4 authors, Gary A Levy.
Rambam Maimonides Med J, 2015 Aug 05; 6(3). PMID: 26241231    Free PMC article.
Citrate Attenuates Adenine-Induced Chronic Renal Failure in Rats by Modulating the Th17/Treg Cell Balance.
Yan Ou, Shuiqin Li, +10 authors, Zhaoyang Duan.
Inflammation, 2015 Aug 09; 39(1). PMID: 26253296
Continuum model of T-cell avidity: Understanding autoreactive and regulatory T-cell responses in type 1 diabetes.
Majid Jaberi-Douraki, Massimo Pietropaolo, Anmar Khadra.
J Theor Biol, 2015 Aug 15; 383. PMID: 26271890    Free PMC article.
Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology.
Kuti Baruch, Neta Rosenzweig, +7 authors, Michal Schwartz.
Nat Commun, 2015 Aug 19; 6. PMID: 26284939    Free PMC article.
Highly Cited.
Low-level regulatory T-cell activity is essential for functional type-2 effector immunity to expel gastrointestinal helminths.
K A Smith, K J Filbey, +6 authors, R M Maizels.
Mucosal Immunol, 2015 Aug 20; 9(2). PMID: 26286232    Free PMC article.
Foxp3-modified bone marrow mesenchymal stem cells promotes liver allograft tolerance through the generation of regulatory T cells in rats.
Haizhi Qi, Guangshun Chen, +2 authors, Jiequn Li.
J Transl Med, 2015 Aug 22; 13. PMID: 26293578    Free PMC article.
Immunology of hepatocellular carcinoma.
Meenakshi Sachdeva, Yogesh K Chawla, Sunil K Arora.
World J Hepatol, 2015 Aug 25; 7(17). PMID: 26301050    Free PMC article.
Review.
Safety and efficacy of hCDR1 (Edratide) in patients with active systemic lupus erythematosus: results of phase II study.
Murray B Urowitz, David A Isenberg, Daniel J Wallace.
Lupus Sci Med, 2015 Aug 25; 2(1). PMID: 26301100    Free PMC article.
Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells.
Takashi Sekiya, Taisuke Kondo, +3 authors, Akihiko Yoshimura.
J Exp Med, 2015 Aug 26; 212(10). PMID: 26304965    Free PMC article.
A Short Peptide That Mimics the Binding Domain of TGF-β1 Presents Potent Anti-Inflammatory Activity.
Emília R Vaz, Patrícia T Fujimura, +10 authors, Carlos Ueira-Vieira.
PLoS One, 2015 Aug 28; 10(8). PMID: 26312490    Free PMC article.
A Distinct Function of Regulatory T Cells in Tissue Protection.
Nicholas Arpaia, Jesse A Green, +5 authors, Alexander Y Rudensky.
Cell, 2015 Sep 01; 162(5). PMID: 26317471    Free PMC article.
Highly Cited.
Non-suppressive regulatory T cell subset expansion in pulmonary arterial hypertension.
Yoshiharu Sada, Yoshihiro Dohi, +3 authors, Yasuki Kihara.
Heart Vessels, 2015 Sep 01; 31(8). PMID: 26319442
Moxibustion and Acupuncture Ameliorate Crohn's Disease by Regulating the Balance between Th17 and Treg Cells in the Intestinal Mucosa.
Chen Zhao, Chunhui Bao, +9 authors, Huangan Wu.
Evid Based Complement Alternat Med, 2015 Sep 09; 2015. PMID: 26347488    Free PMC article.
Mechanisms of Cholera Toxin in the Modulation of TH17 Responses.
Hsing-Chuan Tsai, Reen Wu.
Crit Rev Immunol, 2015 Sep 10; 35(2). PMID: 26351147    Free PMC article.
Review.
Hypoxia-inducible factors in T lymphocyte differentiation and function. A Review in the Theme: Cellular Responses to Hypoxia.
Jin-Hui Tao, Joseph Barbi, Fan Pan.
Am J Physiol Cell Physiol, 2015 Sep 12; 309(9). PMID: 26354751    Free PMC article.
Review.
Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents.
Ao Guo, Dongming He, +2 authors, Jian Zhao.
Sci Rep, 2015 Sep 16; 5. PMID: 26370586    Free PMC article.
The RUNX complex: reaching beyond haematopoiesis into immunity.
Dominic Chih-Cheng Voon, Yit Teng Hor, Yoshiaki Ito.
Immunology, 2015 Sep 25; 146(4). PMID: 26399680    Free PMC article.
Review.
A microfluidic platform reveals differential response of regulatory T cells to micropatterned costimulation arrays.
Joung-Hyun Lee, Michael L Dustin, Lance C Kam.
Integr Biol (Camb), 2015 Sep 25; 7(11). PMID: 26400012    Free PMC article.
Epigenetic control of the immune system: a lesson from Kabuki syndrome.
Stefano Stagi, Anna Virginia Gulino, Elisabetta Lapi, Donato Rigante.
Immunol Res, 2015 Sep 29; 64(2). PMID: 26411453
Review.
Quantitative activation suppression assay to evaluate human bone marrow-derived mesenchymal stromal cell potency.
Bahey Salem, Samantha Miner, +8 authors, A John Barrett.
Cytotherapy, 2015 Oct 01; 17(12). PMID: 26422657    Free PMC article.
MiR-125a-5p Decreases the Sensitivity of Treg cells Toward IL-6-Mediated Conversion by Inhibiting IL-6R and STAT3 Expression.
Dan Li, Chao Kong, +7 authors, Bin Li.
Sci Rep, 2015 Oct 02; 5. PMID: 26424054    Free PMC article.
Poly(ADP-ribosyl)ation of FOXP3 Protein Mediated by PARP-1 Protein Regulates the Function of Regulatory T Cells.
Xuerui Luo, Jia Nie, +5 authors, Bin Li.
J Biol Chem, 2015 Oct 03; 290(48). PMID: 26429911    Free PMC article.
Successful treatment of murine autoimmune cholangitis by parabiosis: Implications for hematopoietic therapy.
Jing-Bo Yang, Yin-Hu Wang, +9 authors, Zhe-Xiong Lian.
J Autoimmun, 2015 Oct 04; 66. PMID: 26432598    Free PMC article.
Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors.
Emily J Colbeck, James P Hindley, +11 authors, Awen M Gallimore.
Oncotarget, 2015 Oct 05; 6(28). PMID: 26433463    Free PMC article.
In vivo induction of regulatory T cells for immune tolerance in hemophilia.
Xiaomei Wang, Cox Terhorst, Roland W Herzog.
Cell Immunol, 2015 Oct 12; 301. PMID: 26454643    Free PMC article.
Review.
Prognostic value of tumor-infiltrating FoxP3+ regulatory T cells in cancers: a systematic review and meta-analysis.
Bin Shang, Yao Liu, Shu-juan Jiang, Yi Liu.
Sci Rep, 2015 Oct 16; 5. PMID: 26462617    Free PMC article.
Highly Cited. Systematic Review.
Roles of Foxp3 in the occurrence and development of cervical cancer.
Qingshuang Luo, Shulan Zhang, +2 authors, Huijie Zhang.
Int J Clin Exp Pathol, 2015 Oct 16; 8(8). PMID: 26464616    Free PMC article.
TCR usage, gene expression and function of two distinct FOXP3(+)Treg subsets within CD4(+)CD25(hi) T cells identified by expression of CD39 and CD45RO.
Lingying Ye, Jane C Goodall, +13 authors, Huji Xu.
Immunol Cell Biol, 2015 Oct 16; 94(3). PMID: 26467610
CpG expedites regression of local and systemic tumors when combined with activatable nanodelivery.
Azadeh Kheirolomoom, Elizabeth S Ingham, +8 authors, Katherine W Ferrara.
J Control Release, 2015 Oct 17; 220(Pt A). PMID: 26471394    Free PMC article.
The Genotype of the Donor for the (GT)n Polymorphism in the Promoter/Enhancer of FOXP3 Is Associated with the Development of Severe Acute GVHD but Does Not Affect the GVL Effect after Myeloablative HLA-Identical Allogeneic Stem Cell Transplantation.
Víctor Noriega, Carolina Martínez-Laperche, +27 authors, Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group (GETH).
PLoS One, 2015 Oct 17; 10(10). PMID: 26473355    Free PMC article.
Regulatory T Cells Are Critical for Clearing Influenza A Virus in Neonatal Mice.
Samantha Oliphant, J Louise Lines, Melissa L Hollifield, Beth A Garvy.
Viral Immunol, 2015 Oct 27; 28(10). PMID: 26501792    Free PMC article.
The reduced soluble fibrinogen-like protein 2 and regulatory T cells in acute coronary syndrome.
Kun Liu, Ting Li, +4 authors, Zhaohui Wang.
Exp Biol Med (Maywood), 2015 Oct 31; 241(4). PMID: 26515143    Free PMC article.
A critical role for alpha-synuclein in development and function of T lymphocytes.
Afshin Shameli, Wenbin Xiao, +5 authors, Robert W Maitta.
Immunobiology, 2015 Nov 01; 221(2). PMID: 26517968    Free PMC article.
Transforming growth factor-β1 sustains the survival of Foxp3(+) regulatory cells during late phase of oropharyngeal candidiasis infection.
N Bhaskaran, C Quigley, +3 authors, P Pandiyan.
Mucosal Immunol, 2015 Nov 05; 9(4). PMID: 26530137    Free PMC article.
Adipose-Derived Mesenchymal Stem Cells Prevent Systemic Bone Loss in Collagen-Induced Arthritis.
Manasa G Garimella, Supinder Kour, +7 authors, Mohan R Wani.
J Immunol, 2015 Nov 06; 195(11). PMID: 26538398    Free PMC article.
Lack of association between interleukin-2 (IL-2) gene rs2069762 polymorphism and cancer risk: a meta-analysis.
Yafeng Wang, Yun Shu, +3 authors, Weifeng Tang.
Int J Clin Exp Med, 2015 Nov 10; 8(8). PMID: 26550166    Free PMC article.
Cell-based Hyper-interleukin 6 or Hyper-interleukin 11 secreting vaccines combined with low dose cyclophosphamide in an orthotopic murine prostate cancer model.
Jacek Mackiewicz, Marek Kotlarski, +3 authors, Urszula Kazimierczak.
Contemp Oncol (Pozn), 2015 Nov 12; 19(3). PMID: 26557758    Free PMC article.
Ribavirin contributes to eradicate hepatitis C virus through polarization of T helper 1/2 cell balance into T helper 1 dominance.
Katsuhisa Nakatsuka, Masanori Atsukawa, +2 authors, Chiaki Kawamoto.
World J Hepatol, 2015 Nov 12; 7(25). PMID: 26557951    Free PMC article.
Review.
Reduced β-amyloid pathology in an APP transgenic mouse model of Alzheimer's disease lacking functional B and T cells.
Claudia Späni, Tobias Suter, +6 authors, Luka Kulic.
Acta Neuropathol Commun, 2015 Nov 13; 3. PMID: 26558367    Free PMC article.
Insights into the Role of Chemokines, Damage-Associated Molecular Patterns, and Lymphocyte-Derived Mediators from Computational Models of Trauma-Induced Inflammation.
Rami A Namas, Qi Mi, +9 authors, Yoram Vodovotz.
Antioxid Redox Signal, 2015 Nov 13; 23(17). PMID: 26560096    Free PMC article.
Review.
New Insights about Treg and Th17 Cells in HIV Infection and Disease Progression.
Jacqueline María Valverde-Villegas, Maria Cristina Cotta Matte, Rúbia Marília de Medeiros, José Artur Bogo Chies.
J Immunol Res, 2015 Nov 17; 2015. PMID: 26568963    Free PMC article.
Review.
CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion.
Francois P Legoux, Jong-Baeck Lim, +6 authors, James J Moon.
Immunity, 2015 Nov 18; 43(5). PMID: 26572061    Free PMC article.
Highly Cited.
Inhibitor of NFκB Kinase Subunit 2 Blockade Hinders the Initiation but Aggravates the Progression of Crescentic GN.
Janine Gotot, Eveline Piotrowski, +8 authors, Friedrich Thaiss.
J Am Soc Nephrol, 2015 Nov 18; 27(7). PMID: 26574045    Free PMC article.
Characterization of the inflammatory cell infiltrate and expression of costimulatory molecules in chronic echinococcus granulosus infection of the human liver.
A Vatankhah, J Halász, +3 authors, J Tímár.
BMC Infect Dis, 2015 Nov 19; 15. PMID: 26578348    Free PMC article.
Adipose tissue macrophages induce PPARγ-high FOXP3(+) regulatory T cells.
Toshiharu Onodera, Atsunori Fukuhara, +6 authors, Iichiro Shimomura.
Sci Rep, 2015 Nov 20; 5. PMID: 26582486    Free PMC article.
T Helper Lymphocyte Subsets and Plasticity in Autoimmunity and Cancer: An Overview.
Ekaterina A Ivanova, Alexander N Orekhov.
Biomed Res Int, 2015 Nov 20; 2015. PMID: 26583100    Free PMC article.
Review.
The Role of Regulatory CD4 T Cells in Maintaining Tolerance in a Mouse Model of Autoimmune Hepatitis.
Ira An Haack, Katja Derkow, +4 authors, Eckart Schott.
PLoS One, 2015 Nov 26; 10(11). PMID: 26599014    Free PMC article.
The Dynamics of Treg/Th17 and the Imbalance of Treg/Th17 in Clonorchis sinensis-Infected Mice.
Chao Yan, Bei-Bei Zhang, +9 authors, Kui-Yang Zheng.
PLoS One, 2015 Nov 26; 10(11). PMID: 26599407    Free PMC article.
Role of immune tolerance in BALB/c mice with anaphylactic shock after Echinococcus granulosus infection.
Qin Zhang, Jian-Rong Ye, +3 authors, Hong Zheng.
Immunol Res, 2015 Nov 26; 64(1). PMID: 26603168
Predicting prognosis and therapeutic response from interactions between lymphocytes and tumor cells.
David A Quigley, Vessela Kristensen.
Mol Oncol, 2015 Nov 27; 9(10). PMID: 26607741    Free PMC article.
Review.
TGF-β in tolerance, development and regulation of immunity.
Chris J C Johnston, Danielle J Smyth, David W Dresser, Rick M Maizels.
Cell Immunol, 2015 Dec 01; 299. PMID: 26617281    Free PMC article.
Regulatory T Cell Responses to High-Dose Methylprednisolone in Active Systemic Lupus Erythematosus.
Alexis Mathian, Romain Jouenne, +8 authors, Makoto Miyara.
PLoS One, 2015 Dec 03; 10(12). PMID: 26629828    Free PMC article.
Therapies to Preserve β-Cell Function in Type 1 Diabetes.
Johnny Ludvigsson.
Drugs, 2015 Dec 10; 76(2). PMID: 26645223
Review.
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Limin Wu, Nainong Li, +5 authors, Defu Zeng.
Proc Natl Acad Sci U S A, 2015 Dec 10; 112(52). PMID: 26647186    Free PMC article.
Autoimmunity and dysmetabolism of human acquired immunodeficiency syndrome.
Yan-Mei Huang, Xue-Zhi Hong, +3 authors, Hai-Lu Zhao.
Immunol Res, 2015 Dec 18; 64(3). PMID: 26676359
Review.
TCR Signaling in T Cell Memory.
Mark A Daniels, Emma Teixeiro.
Front Immunol, 2015 Dec 24; 6. PMID: 26697013    Free PMC article.
Review.
T follicular helper cells, T follicular regulatory cells and autoimmunity.
Yangyang Zhu, Le Zou, Yun-Cai Liu.
Int Immunol, 2015 Dec 31; 28(4). PMID: 26714592    Free PMC article.
Review.
Role for urinary biomarkers in diagnosis of acute rejection in the transplanted kidney.
Basma Merhi, George Bayliss, Reginald Y Gohh.
World J Transplant, 2016 Jan 02; 5(4). PMID: 26722652    Free PMC article.
Review.
FOXP3+ Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum: The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly.
Audrey Romano, Xunya Hou, +15 authors, Alain Dessein.
PLoS Negl Trop Dis, 2016 Jan 06; 10(1). PMID: 26731721    Free PMC article.
Gfi1, a transcriptional repressor, inhibits the induction of the T helper type 1 programme in activated CD4 T cells.
Junpei Suzuki, Saho Maruyama, +8 authors, Masakatsu Yamashita.
Immunology, 2016 Jan 11; 147(4). PMID: 26749286    Free PMC article.
Novel concept of iSALT (inducible skin-associated lymphoid tissue) in the elicitation of allergic contact dermatitis.
Tetsuya Honda, Kenji Kabashima.
Proc Jpn Acad Ser B Phys Biol Sci, 2016 Jan 13; 92(1). PMID: 26755397    Free PMC article.
Review.
Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology.
Marcela Montes de Oca, Rajiv Kumar, +17 authors, Christian R Engwerda.
PLoS Pathog, 2016 Jan 15; 12(1). PMID: 26765224    Free PMC article.
Neuroprotective effects of bee venom phospholipase A2 in the 3xTg AD mouse model of Alzheimer's disease.
Minsook Ye, Hwan-Suck Chung, +6 authors, Hyunsu Bae.
J Neuroinflammation, 2016 Jan 17; 13. PMID: 26772975    Free PMC article.
Regulatory T Cell Immunotherapy in Immune-Mediated Diseases.
Antonio Pierini, Dominik Schneidawind, Hidekazu Nishikii, Robert S Negrin.
Curr Stem Cell Rep, 2016 Jan 19; 1(4). PMID: 26779417    Free PMC article.
Nanotechnology as a New Therapeutic Approach to Prevent the HIV-Infection of Treg Cells.
Didiana Jaramillo-Ruiz, Francisco Javier De La Mata, +2 authors, M Ángeles Muñoz-Fernández.
PLoS One, 2016 Jan 20; 11(1). PMID: 26785250    Free PMC article.
Graded Foxo1 activity in Treg cells differentiates tumour immunity from spontaneous autoimmunity.
Chong T Luo, Will Liao, +2 authors, Ming O Li.
Nature, 2016 Jan 21; 529(7587). PMID: 26789248    Free PMC article.
Highly Cited.
Targeting Th17 Cells with Small Molecules and Small Interference RNA.
Hui Lin, Pingfang Song, +3 authors, Cong-Qiu Chu.
Mediators Inflamm, 2016 Jan 23; 2015. PMID: 26792955    Free PMC article.
Review.
MHC-compatible bone marrow stromal/stem cells trigger fibrosis by activating host T cells in a scleroderma mouse model.
Yoko Ogawa, Satoru Morikawa, +12 authors, Shigeto Shimmura.
Elife, 2016 Jan 27; 5. PMID: 26809474    Free PMC article.
Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1.
Evita Bothur, Hartmann Raifer, +19 authors, Michael Lohoff.
Nat Commun, 2016 Jan 28; 6. PMID: 26815406    Free PMC article.
CD4(+) T cell anergy prevents autoimmunity and generates regulatory T cell precursors.
Lokesh A Kalekar, Shirdi E Schmiel, +12 authors, Daniel L Mueller.
Nat Immunol, 2016 Feb 02; 17(3). PMID: 26829766    Free PMC article.
Highly Cited.
SHARPIN controls regulatory T cells by negatively modulating the T cell antigen receptor complex.
Yoon Park, Hyung-Seung Jin, +4 authors, Yun-Cai Liu.
Nat Immunol, 2016 Feb 02; 17(3). PMID: 26829767    Free PMC article.
The role of inflammation in the pathology of preeclampsia.
Ashlyn C Harmon, Denise C Cornelius, +4 authors, Babbette LaMarca.
Clin Sci (Lond), 2016 Feb 06; 130(6). PMID: 26846579    Free PMC article.
Highly Cited. Review.
Genetics of autoimmune diseases: perspectives from genome-wide association studies.
Yuta Kochi.
Int Immunol, 2016 Feb 10; 28(4). PMID: 26857735    Free PMC article.
Review.
Regulatory T Cells in Melanoma Revisited by a Computational Clustering of FOXP3+ T Cell Subpopulations.
Hiroko Fujii, Julie Josse, +3 authors, Masahiro Ono.
J Immunol, 2016 Feb 13; 196(6). PMID: 26864030    Free PMC article.
The human HSP70 family of chaperones: where do we stand?
Jürgen Radons.
Cell Stress Chaperones, 2016 Feb 13; 21(3). PMID: 26865365    Free PMC article.
Highly Cited. Review.
CD4+ T-cell subsets in inflammatory diseases: beyond the Th1/Th2 paradigm.
Kiyoshi Hirahara, Toshinori Nakayama.
Int Immunol, 2016 Feb 14; 28(4). PMID: 26874355    Free PMC article.
Highly Cited. Review.
In Vivo Expansion of Regulatory T Cells by Low-Dose Interleukin-2 Treatment Increases Allograft Survival in Corneal Transplantation.
Maryam Tahvildari, Masahiro Omoto, +6 authors, Reza Dana.
Transplantation, 2016 Feb 18; 100(3). PMID: 26881788    Free PMC article.
The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function.
Samuel E Marsh, Edsel M Abud, +10 authors, Mathew Blurton-Jones.
Proc Natl Acad Sci U S A, 2016 Feb 18; 113(9). PMID: 26884167    Free PMC article.
Highly Cited.
Imbalance of Th17/Tregs in rats with smoke inhalation-induced acute lung injury.
Fan Zhang, Mian-yang Li, Ya-ting Lan, Cheng-bin Wang.
Sci Rep, 2016 Feb 18; 6. PMID: 26884314    Free PMC article.
Subconjunctival injection of in vitro transforming growth factor-β-induced regulatory T cells prolongs allogeneic corneal graft survival in mice.
Qing Xu, Xiaobo Tan, +2 authors, Zhiqiang Pan.
Int J Clin Exp Med, 2016 Feb 18; 8(11). PMID: 26884940    Free PMC article.
Combining FoxP3 and Helios with GARP/LAP markers can identify expanded Treg subsets in cancer patients.
May Abd Al Samid, Belal Chaudhary, +2 authors, Eyad Elkord.
Oncotarget, 2016 Feb 18; 7(12). PMID: 26885615    Free PMC article.
The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements.
Claudio Procaccini, Fortunata Carbone, +12 authors, Giuseppe Matarese.
Immunity, 2016 Feb 18; 44(2). PMID: 26885861    Free PMC article.
Highly Cited.
Metabolism of murine TH 17 cells: Impact on cell fate and function.
Ran Wang, Laura A Solt.
Eur J Immunol, 2016 Feb 20; 46(4). PMID: 26893133    Free PMC article.
Review.
Treg activation defect in type 1 diabetes: correction with TNFR2 agonism.
Yoshiaki Okubo, Heather Torrey, +2 authors, Denise L Faustman.
Clin Transl Immunology, 2016 Feb 24; 5(1). PMID: 26900470    Free PMC article.
Control of Foxp3 stability through modulation of TET activity.
Xiaojing Yue, Sara Trifari, +9 authors, Anjana Rao.
J Exp Med, 2016 Feb 24; 213(3). PMID: 26903244    Free PMC article.
Highly Cited.
Development of Type 2, But Not Type 1, Leprosy Reactions is Associated with a Severe Reduction of Circulating and In situ Regulatory T-Cells.
Ana Paula Vieira, Maria Ângela Bianconcini Trindade, +4 authors, Gil Benard.
Am J Trop Med Hyg, 2016 Feb 24; 94(4). PMID: 26903606    Free PMC article.
Cellular senescence impact on immune cell fate and function.
Rita Vicente, Anne-Laure Mausset-Bonnefont, +2 authors, Jean-Marc Brondello.
Aging Cell, 2016 Feb 26; 15(3). PMID: 26910559    Free PMC article.
Review.
Kinsenoside inhibits the inflammatory mediator release in a type-II collagen induced arthritis mouse model by regulating the T cells responses.
Hung-Bo Hsiao, Chang-Chi Hsieh, +2 authors, Wen-Chuan Lin.
BMC Complement Altern Med, 2016 Feb 27; 16. PMID: 26916550    Free PMC article.
Increased generation of Foxp3(+) regulatory T cells by manipulating antigen presentation in the thymus.
Jiqiang Lin, Lu Yang, +5 authors, Juan J Lafaille.
Nat Commun, 2016 Mar 01; 7. PMID: 26923114    Free PMC article.
SHARPIN controls the development of regulatory T cells.
Vanessa Redecke, Vandana Chaturvedi, Jeeba Kuriakose, Hans Häcker.
Immunology, 2016 Mar 05; 148(2). PMID: 26931177    Free PMC article.
Local delivery of CpG-B and GM-CSF induces concerted activation of effector and regulatory T cells in the human melanoma sentinel lymph node.
Mari F C M van den Hout, Berbel J R Sluijter, +5 authors, Tanja D de Gruijl.
Cancer Immunol Immunother, 2016 Mar 05; 65(4). PMID: 26935057    Free PMC article.
Induced Treg Cells Augment the Th17-Mediated Intestinal Inflammatory Response in a CTLA4-Dependent Manner.
Nobumasa Watanabe, Osamu Kaminuma, Noriko Kitamura, Takachika Hiroi.
PLoS One, 2016 Mar 08; 11(3). PMID: 26950218    Free PMC article.
A high number of IgG4-positive cells in gastric cancer tissue is associated with tumor progression and poor prognosis.
Kozo Miyatani, Hiroaki Saito, +8 authors, Masahide Ikeguchi.
Virchows Arch, 2016 Mar 10; 468(5). PMID: 26951261
Dexamethasone attenuates echinococcosis-induced allergic reactions via regulatory T cells in mice.
Qin Zhang, Jianrong Ye, Hong Zheng.
BMC Immunol, 2016 Mar 13; 17. PMID: 26968945    Free PMC article.
Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors.
Joanna Kopecka, Stefania Porto, +9 authors, Chiara Riganti.
Oncotarget, 2016 Mar 17; 7(15). PMID: 26980746    Free PMC article.
Materials that harness and modulate the immune system.
Jamal S Lewis, Krishnendu Roy, Benjamin G Keselowsky.
MRS Bull, 2014 Jan 01; 39(1). PMID: 26997752    Free PMC article.
Overexpression of interleukin-35 associates with hepatocellular carcinoma aggressiveness and recurrence after curative resection.
Yi-Peng Fu, Yong Yi, +10 authors, Shuang-Jian Qiu.
Br J Cancer, 2016 Mar 24; 114(7). PMID: 27002937    Free PMC article.
Ubiquitin signaling in immune responses.
Hongbo Hu, Shao-Cong Sun.
Cell Res, 2016 Mar 26; 26(4). PMID: 27012466    Free PMC article.
Highly Cited. Review.
Regulation of the Adaptive Immune Response by the IκB Family Protein Bcl-3.
Felicity D Herrington, Robert J B Nibbs.
Cells, 2016 Mar 31; 5(2). PMID: 27023613    Free PMC article.
Review.
T cell receptor signalling in the control of regulatory T cell differentiation and function.
Ming O Li, Alexander Y Rudensky.
Nat Rev Immunol, 2016 Mar 31; 16(4). PMID: 27026074    Free PMC article.
Highly Cited. Review.
Post-transplant bendamustine reduces GvHD while preserving GvL in experimental haploidentical bone marrow transplantation.
Jessica Stokes, Emely A Hoffman, +2 authors, Emmanuel Katsanis.
Br J Haematol, 2016 Apr 01; 174(1). PMID: 27030315    Free PMC article.
Narrow-Band Ultraviolet B Phototherapy Ameliorates Acute Graft-Versus-Host Disease of the Intestine by Expansion of Regulatory T Cells.
Akari Hashimoto, Tsutomu Sato, +12 authors, Junji Kato.
PLoS One, 2016 Apr 01; 11(3). PMID: 27031239    Free PMC article.
Dendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells.
Daniel S Leventhal, Dana C Gilmore, +9 authors, Peter A Savage.
Immunity, 2016 Apr 03; 44(4). PMID: 27037189    Free PMC article.
Effects of conventional immunosuppressive treatment on CD244+ (CD28null) and FOXP3+ T cells in the inflamed muscle of patients with polymyositis and dermatomyositis.
Jayesh M Pandya, Ingela Loell, +5 authors, Vivianne Malmström.
Arthritis Res Ther, 2016 Apr 04; 18. PMID: 27039301    Free PMC article.
Nuclear transfer nTreg model reveals fate-determining TCR-β and novel peripheral nTreg precursors.
Manching Ku, Shih-En Chang, +6 authors, Oktay Kirak.
Proc Natl Acad Sci U S A, 2016 Apr 05; 113(16). PMID: 27044095    Free PMC article.
TCR transgenic mice reveal the impact of type 1 diabetes loci on early and late disease checkpoints.
Erin E Hillhouse, Adrian Liston, +3 authors, Sylvie Lesage.
Immunol Cell Biol, 2016 Apr 06; 94(7). PMID: 27046082
Molecular and cellular mechanisms of food allergy and food tolerance.
R Sharon Chinthrajah, Joseph D Hernandez, +2 authors, Kari C Nadeau.
J Allergy Clin Immunol, 2016 Apr 10; 137(4). PMID: 27059726    Free PMC article.
Highly Cited. Review.
Placental Ischemia and Resultant Phenotype in Animal Models of Preeclampsia.
Babbette LaMarca, Lorena M Amaral, +3 authors, Mark W Cunningham.
Curr Hypertens Rep, 2016 Apr 15; 18(5). PMID: 27076345    Free PMC article.
Review.
NADPH oxidase deficiency underlies dysfunction of aged CD8+ Tregs.
Zhenke Wen, Yasuhiro Shimojima, +6 authors, Cornelia M Weyand.
J Clin Invest, 2016 Apr 19; 126(5). PMID: 27088800    Free PMC article.
Impaired coronary microcirculation in type 2 diabetic patients is associated with elevated circulating regulatory T cells and reduced number of IL-21R⁺ T cells.
Bernt Johan von Scholten, Alexander Rosendahl, +4 authors, Tine W Hansen.
Cardiovasc Diabetol, 2016 Apr 21; 15. PMID: 27095356    Free PMC article.
Phenotypical characterization of regulatory T cells in humans and rodents.
A L Rodríguez-Perea, E D Arcia, C M Rueda, P A Velilla.
Clin Exp Immunol, 2016 Apr 29; 185(3). PMID: 27124481    Free PMC article.
Review.
Autoantigen-specific immunosuppression with tolerogenic peripheral blood cells prevents relapses in a mouse model of relapsing-remitting multiple sclerosis.
Christian Kleist, Elisabeth Mohr, +7 authors, Peter Terness.
J Transl Med, 2016 May 02; 14(1). PMID: 27131971    Free PMC article.
Lower omental t-regulatory cell count is associated with higher fasting glucose and lower β-cell function in adults with obesity.
Lauren E Gyllenhammer, Jonathan Lam, +4 authors, Michael I Goran.
Obesity (Silver Spring), 2016 May 03; 24(6). PMID: 27133873    Free PMC article.
Anti-CCR4 monoclonal antibody enhances antitumor immunity by modulating tumor-infiltrating Tregs in an ovarian cancer xenograft humanized mouse model.
De-Kuan Chang, Eric Peterson, +6 authors, Wayne A Marasco.
Oncoimmunology, 2016 May 04; 5(3). PMID: 27141347    Free PMC article.
Phase Ib study of poly-epitope peptide vaccination to thymidylate synthase (TSPP) and GOLFIG chemo-immunotherapy for treatment of metastatic colorectal cancer patients.
Pierpaolo Correale, Cirino Botta, +14 authors, Maria Grazia Cusi.
Oncoimmunology, 2016 May 04; 5(4). PMID: 27141384    Free PMC article.
Association between two interleukin-2 gene polymorphisms and cancer susceptibility: a meta-analysis.
Meng Zhang, Xiuxiu Tan, +7 authors, Chaozhao Liang.
Onco Targets Ther, 2016 May 05; 9. PMID: 27143914    Free PMC article.
Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis.
Sara Tengvall, Tove Eneljung, +9 authors, Inger Gjertsson.
PLoS One, 2016 May 10; 11(5). PMID: 27159398    Free PMC article.
Both tumour cells and infiltrating T-cells in equine sarcoids express FOXP3 associated with an immune-supressed cytokine microenvironment.
A Douglas Wilson, Chelsea Hicks.
Vet Res, 2016 May 11; 47(1). PMID: 27160146    Free PMC article.
Co-stimulatory and Co-inhibitory Pathways in Autoimmunity.
Qianxia Zhang, Dario A A Vignali.
Immunity, 2016 May 19; 44(5). PMID: 27192568    Free PMC article.
Highly Cited. Review.
Utilizing cell-based therapeutics to overcome immune evasion in hematologic malignancies.
Chuang Sun, Gianpietro Dotti, Barbara Savoldo.
Blood, 2016 May 22; 127(26). PMID: 27207792    Free PMC article.
Review.
Until Death Do Us Part: Necrosis and Oxidation Promote the Tumor Microenvironment.
Ramin Lotfi, Christof Kaltenmeier, Michael T Lotze, Christoph Bergmann.
Transfus Med Hemother, 2016 May 27; 43(2). PMID: 27226794    Free PMC article.
Review.
Dynamic changes in immune cell profile in head and neck squamous cell carcinoma: Immunomodulatory effects of chemotherapy.
Hideyuki Takahashi, Koichi Sakakura, +2 authors, Kazuaki Chikamatsu.
Cancer Sci, 2016 May 27; 107(8). PMID: 27228557    Free PMC article.
Functional Mechanisms of Treg in the Context of HIV Infection and the Janus Face of Immune Suppression.
Jacobo López-Abente, Rafael Correa-Rocha, Marjorie Pion.
Front Immunol, 2016 Jun 01; 7. PMID: 27242797    Free PMC article.
Review.
Enhancement of anti-STLV-1/HTLV-1 immune responses through multimodal effects of anti-CCR4 antibody.
Kenji Sugata, Jun-Ichirou Yasunaga, +9 authors, Masao Matsuoka.
Sci Rep, 2016 Jun 03; 6. PMID: 27250643    Free PMC article.
Zinc supplementation induces CD4+CD25+Foxp3+ antigen-specific regulatory T cells and suppresses IFN-γ production by upregulation of Foxp3 and KLF-10 and downregulation of IRF-1.
Martina Maywald, Lothar Rink.
Eur J Nutr, 2016 Jun 05; 56(5). PMID: 27260002
Gingival Mesenchymal Stem/Progenitor Cells: A Unique Tissue Engineering Gem.
Karim M Fawzy El-Sayed, Christof E Dörfer.
Stem Cells Int, 2016 Jun 18; 2016. PMID: 27313628    Free PMC article.
Review.
Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance.
Lei Gu, Wen-Sheng Deng, +2 authors, Qing Xu.
Mol Med Rep, 2016 Jun 18; 14(2). PMID: 27315465    Free PMC article.
Cell Therapy for Prophylactic Tolerance in Immunoglobulin E-mediated Allergy.
Ulrike Baranyi, Andreas M Farkas, +9 authors, Thomas Wekerle.
EBioMedicine, 2016 Jun 21; 7. PMID: 27322476    Free PMC article.
Preeclampsia and health risks later in life: an immunological link.
Shi-Bin Cheng, Surendra Sharma.
Semin Immunopathol, 2016 Jun 25; 38(6). PMID: 27339196
Review.
Hydrophobic CDR3 residues promote the development of self-reactive T cells.
Brian D Stadinski, Karthik Shekhar, +6 authors, Eric S Huseby.
Nat Immunol, 2016 Jun 28; 17(8). PMID: 27348411    Free PMC article.
Highly Cited.
Amelioration of autoimmune arthritis by adoptive transfer of Foxp3-expressing regulatory B cells is associated with the Treg/Th17 cell balance.
Mi-Kyung Park, Young Ok Jung, +11 authors, Jun-Ki Min.
J Transl Med, 2016 Jun 29; 14(1). PMID: 27350539    Free PMC article.
Interactions Between the Immune and the Renin-Angiotensin Systems in Hypertension.
Nathan P Rudemiller, Steven D Crowley.
Hypertension, 2016 Jun 30; 68(2). PMID: 27354427    Free PMC article.
Review.
Altered regulatory T cell phenotype in latent autoimmune diabetes of the adults (LADA).
M Radenkovic, C Silver, +5 authors, C M Cilio.
Clin Exp Immunol, 2016 Jul 01; 186(1). PMID: 27357431    Free PMC article.
TNF-α priming enhances CD4+FoxP3+ regulatory T-cell suppressive function in murine GVHD prevention and treatment.
Antonio Pierini, William Strober, +7 authors, Robert S Negrin.
Blood, 2016 Jul 02; 128(6). PMID: 27365424    Free PMC article.
The CD25-binding antibody Daclizumab High-Yield Process has a distinct glycosylation pattern and reduced antibody-dependent cell-mediated cytotoxicity in comparison to Zenapax®.
Bishu Ganguly, Balaji Balasa, +9 authors, James P Sheridan.
MAbs, 2016 Jul 02; 8(7). PMID: 27367933    Free PMC article.
Classical Hodgkin Lymphoma with Positive Epstein-Barr Virus Status is Associated with More FOXP3 Regulatory T Cells.
Antonia Pavlovic, Merica Glavina Durdov, +2 authors, Maja Bozic Sakic.
Med Sci Monit, 2016 Jul 06; 22. PMID: 27377121    Free PMC article.
CD25+ FoxP3+ Memory CD4 T Cells Are Frequent Targets of HIV Infection In Vivo.
Mkunde Chachage, Georgios Pollakis, +17 authors, Christof Geldmacher.
J Virol, 2016 Jul 08; 90(20). PMID: 27384654    Free PMC article.
The roles of serum CXCL16 in circulating Tregs and gastrointestinal stromal tumor cells.
Ya-Nan Xing, Jun-Yan Zhang, Hui-Mian Xu.
Onco Targets Ther, 2016 Jul 16; 9. PMID: 27418838    Free PMC article.
Hydrogen Sulfide Regulates Homeostasis of Mesenchymal Stem Cells and Regulatory T Cells.
R Yang, Y Liu, S Shi.
J Dent Res, 2016 Jul 20; 95(13). PMID: 27432317    Free PMC article.
Review.
IL-10+ regulatory B cells are enriched in cord blood and may protect against cGVHD after cord blood transplantation.
Anushruti Sarvaria, Rafet Basar, +19 authors, Katayoun Rezvani.
Blood, 2016 Jul 22; 128(10). PMID: 27439912    Free PMC article.
Analysis of the immune microenvironment in resected non-small cell lung cancer: the prognostic value of different T lymphocyte markers.
Marta Usó, Eloisa Jantus-Lewintre, +11 authors, Rafael Sirera.
Oncotarget, 2016 Jul 28; 7(33). PMID: 27463005    Free PMC article.
Herbal Medicines for Asthmatic Inflammation: From Basic Researches to Clinical Applications.
Fang Liu, Nan-Xia Xuan, +3 authors, Hua-Hao Shen.
Mediators Inflamm, 2016 Aug 02; 2016. PMID: 27478309    Free PMC article.
Review.
New horizon for radical cure of chronic hepatitis B virus infection.
Kazuto Tajiri, Yukihiro Shimizu.
World J Hepatol, 2016 Aug 02; 8(21). PMID: 27478536    Free PMC article.
Oral Squamous Carcinoma Cells Express B7-H1 and B7-DC Receptors in Vivo.
Sabine Groeger, H P Howaldt, +3 authors, J Meyle.
Pathol Oncol Res, 2016 Aug 09; 23(1). PMID: 27498988
Regulatory T Cells in the Tumor Microenvironment and Cancer Progression: Role and Therapeutic Targeting.
Belal Chaudhary, Eyad Elkord.
Vaccines (Basel), 2016 Aug 12; 4(3). PMID: 27509527    Free PMC article.
Highly Cited. Review.
Clinical significance of T cell metabolic reprogramming in cancer.
Christoph Herbel, Nikolaos Patsoukis, +3 authors, Vassiliki A Boussiotis.
Clin Transl Med, 2016 Aug 12; 5(1). PMID: 27510264    Free PMC article.
Review.
Transcriptome analysis reveals regional and temporal differences in mucosal immune system development in the small intestine of neonatal calves.
Guanxiang Liang, Nilusha Malmuthuge, +3 authors, Le Luo Guan.
BMC Genomics, 2016 Aug 16; 17(1). PMID: 27515123    Free PMC article.
Association between IL28B rs12979860 single nucleotide polymorphism and the frequency of colonic Treg in chronically HCV-infected patients.
Minesh Mehta, Helal F Hetta, +13 authors, Mohamed Tarek M Shata.
Arch Virol, 2016 Aug 22; 161(11). PMID: 27544760    Free PMC article.
Modulation of Alloimmunity by Heat Shock Proteins.
Thiago J Borges, Benjamin J Lang, Rafael L Lopes, Cristina Bonorino.
Front Immunol, 2016 Aug 25; 7. PMID: 27555846    Free PMC article.
Review.
Selective Memory to Apoptotic Cell-Derived Self-Antigens with Implications for Systemic Lupus Erythematosus Development.
Amanda Duhlin, Yunying Chen, +8 authors, Mikael C I Karlsson.
J Immunol, 2016 Aug 26; 197(7). PMID: 27559051    Free PMC article.
Predictive biomarkers of response to PD-1/PD-L1 immune checkpoint inhibitors in non-small cell lung cancer.
Kazuhiko Shien, Vassiliki A Papadimitrakopoulou, Ignacio I Wistuba.
Lung Cancer, 2016 Aug 28; 99. PMID: 27565919    Free PMC article.
Review.
Leptin Enhances TH2 and ILC2 Responses in Allergic Airway Disease.
Handong Zheng, Xing Zhang, +3 authors, Xuexian O Yang.
J Biol Chem, 2016 Aug 28; 291(42). PMID: 27566543    Free PMC article.
Immunobiology of hepatocarcinogenesis: Ways to go or almost there?
Pavan Patel, Steven E Schutzer, Nikolaos Pyrsopoulos.
World J Gastrointest Pathophysiol, 2016 Aug 31; 7(3). PMID: 27574562    Free PMC article.
Review.
Bach2-Batf interactions control Th2-type immune response by regulating the IL-4 amplification loop.
Makoto Kuwahara, Wataru Ise, +14 authors, Masakatsu Yamashita.
Nat Commun, 2016 Sep 02; 7. PMID: 27581382    Free PMC article.
LuxGLM: a probabilistic covariate model for quantification of DNA methylation modifications with complex experimental designs.
Tarmo Äijö, Xiaojing Yue, Anjana Rao, Harri Lähdesmäki.
Bioinformatics, 2016 Sep 03; 32(17). PMID: 27587669    Free PMC article.
Cigarette Smoke Induces Immune Responses to Vimentin in both, Arthritis-Susceptible and -Resistant Humanized Mice.
Mitali Bidkar, Robert Vassallo, +3 authors, Veena Taneja.
PLoS One, 2016 Sep 08; 11(9). PMID: 27602574    Free PMC article.
Soluble interleukin-2 receptor α and interleukin-2 serum levels in patients with basal cell carcinoma.
Michal Sobjanek, Ewa Bien, +4 authors, Roman Nowicki.
Postepy Dermatol Alergol, 2016 Sep 09; 33(4). PMID: 27605896    Free PMC article.
Notch Signaling and Alloreactivity.
Vedran Radojcic, Ivan Maillard.
Transplantation, 2016 Sep 09; 100(12). PMID: 27607530    Free PMC article.
Review.
The Proportion of Regulatory T Cells in Patients with Rheumatoid Arthritis: A Meta-Analysis.
Takayoshi Morita, Yoshihito Shima, +3 authors, Atsushi Kumanogoh.
PLoS One, 2016 Sep 14; 11(9). PMID: 27622457    Free PMC article.
Systematic Review.
Extraskeletal actions of vitamin D.
Daniel D Bikle.
Ann N Y Acad Sci, 2016 Sep 21; 1376(1). PMID: 27649525    Free PMC article.
Review.
Robust and Accurate Discrimination of Self/Non-Self Antigen Presentations by Regulatory T Cell Suppression.
Chikara Furusawa, Tomoyuki Yamaguchi.
PLoS One, 2016 Sep 27; 11(9). PMID: 27668873    Free PMC article.
Immunomodulation by mesenchymal stem cells: Interplay between mesenchymal stem cells and regulatory lymphocytes.
Oscar Ka-Fai Ma, Koon Ho Chan.
World J Stem Cells, 2016 Sep 30; 8(9). PMID: 27679683    Free PMC article.
Metabolic Interactions in the Gastrointestinal Tract (GIT): Host, Commensal, Probiotics, and Bacteriophage Influences.
Luis Vitetta, Sean Hall, Samantha Coulson.
Microorganisms, 2015 Jan 01; 3(4). PMID: 27682125    Free PMC article.
Review.
Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors.
Kole T Roybal, Jasper Z Williams, +6 authors, Wendell A Lim.
Cell, 2016 Oct 04; 167(2). PMID: 27693353    Free PMC article.
Highly Cited.
Adipose-Derived Mesenchymal Stem Cells Reduce Lymphocytic Infiltration in a Rabbit Model of Induced Autoimmune Dacryoadenitis.
Xue Li, Xiaoxiao Lu, +5 authors, Ruihua Wei.
Invest Ophthalmol Vis Sci, 2016 Oct 05; 57(13). PMID: 27699412    Free PMC article.
Type I Interferons Regulate Immune Responses in Humans with Blood-Stage Plasmodium falciparum Infection.
Marcela Montes de Oca, Rajiv Kumar, +17 authors, Christian R Engwerda.
Cell Rep, 2016 Oct 06; 17(2). PMID: 27705789    Free PMC article.
Umbilical cord-derived mesenchymal stem cells reversed the suppressive deficiency of T regulatory cells from peripheral blood of patients with multiple sclerosis in a co-culture - a preliminary study.
Hongna Yang, Jinhua Sun, +3 authors, Tingyu Qu.
Oncotarget, 2016 Oct 06; 7(45). PMID: 27705922    Free PMC article.
Neuroprotective effects of CD4+CD25+Foxp3+ regulatory T cells in a 3xTg-AD Alzheimer's disease model.
Hyunjung Baek, Minsook Ye, +11 authors, Hyunsu Bae.
Oncotarget, 2016 Oct 08; 7(43). PMID: 27713140    Free PMC article.
Fas-Fas Ligand: Checkpoint of T Cell Functions in Multiple Sclerosis.
Elisabetta Volpe, Manolo Sambucci, Luca Battistini, Giovanna Borsellino.
Front Immunol, 2016 Oct 13; 7. PMID: 27729910    Free PMC article.
Review.
Soluble fibrinogen like protein 2 (sFGL2), the novel effector molecule for immunoregulation.
Xin-Guang Liu, Yu Liu, Feng Chen.
Oncotarget, 2016 Oct 13; 8(2). PMID: 27732962    Free PMC article.
Review.
Enforced Expression of CXCR5 Drives T Follicular Regulatory-Like Features in Foxp3+ T Cells.
Young Uk Kim, Byung-Seok Kim, +2 authors, Yeonseok Chung.
Biomol Ther (Seoul), 2016 Oct 16; 25(2). PMID: 27737526    Free PMC article.
Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.
Michel J Massaad, Jia Zhou, +25 authors, Raif S Geha.
J Clin Invest, 2016 Nov 02; 126(11). PMID: 27760045    Free PMC article.
DR3 signaling modulates the function of Foxp3+ regulatory T cells and the severity of acute graft-versus-host disease.
Hidekazu Nishikii, Byung-Su Kim, +9 authors, Robert S Negrin.
Blood, 2016 Oct 21; 128(24). PMID: 27760760    Free PMC article.
Changes of Regulatory T Cells and of Proinflammatory and Immunosuppressive Cytokines in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.
Yong-Chao Qiao, Jian Shen, +6 authors, Hai-Lu Zhao.
J Diabetes Res, 2016 Oct 26; 2016. PMID: 27777959    Free PMC article.
Systematic Review.
Boosting Tumor-Specific Immunity Using PDT.
Nicole Maeding, Thomas Verwanger, Barbara Krammer.
Cancers (Basel), 2016 Oct 27; 8(10). PMID: 27782066    Free PMC article.
Review.
Block of both TGF-β and IL-2 signaling impedes Neurophilin-1+ regulatory T cell and follicular regulatory T cell development.
Liang Li, Shu-Han Yang, +7 authors, Zhe-Xiong Lian.
Cell Death Dis, 2016 Oct 28; 7(10). PMID: 27787514    Free PMC article.
Tumor infiltrating T lymphocytes expressing FoxP3, CCR7 or PD-1 predict the outcome of prostate cancer patients subjected to salvage radiotherapy after biochemical relapse.
Valerio Nardone, Cirino Botta, +18 authors, Pierpaolo Correale.
Cancer Biol Ther, 2016 Oct 30; 17(11). PMID: 27791459    Free PMC article.
Food allergy: immune mechanisms, diagnosis and immunotherapy.
Wong Yu, Deborah M Hussey Freeland, Kari C Nadeau.
Nat Rev Immunol, 2016 Nov 01; 16(12). PMID: 27795547    Free PMC article.
Highly Cited. Review.
Low-dose IL-2 selectively activates subsets of CD4+ Tregs and NK cells.
Masahiro Hirakawa, Tiago R Matos, +16 authors, Jerome Ritz.
JCI Insight, 2016 Nov 05; 1(18). PMID: 27812545    Free PMC article.
The inhibition of dopamine synthesis in fetuses changes the pattern of T-lymphocyte maturation in the thymus of adult rats.
N V Lifantseva, Ts O Koneeva, +2 authors, V I Melnikova.
Dokl Biochem Biophys, 2016 Nov 07; 470(1). PMID: 27817026
The Roles of CD137 Signaling in Atherosclerosis.
In-Hyuk Jung, Goo Taeg Oh.
Korean Circ J, 2016 Nov 09; 46(6). PMID: 27826331    Free PMC article.
Review.
Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8+ T Cells co-expressing PD-1 and LAG-3 inhibitory receptors.
Ameet K Mishra, Tanya Kadoishi, +4 authors, Jing H Wang.
Oncotarget, 2016 Nov 12; 7(49). PMID: 27835902    Free PMC article.
Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.
Marco De Simone, Alberto Arrigoni, +28 authors, Massimiliano Pagani.
Immunity, 2016 Nov 17; 45(5). PMID: 27851914    Free PMC article.
Highly Cited.
Elevated expression of miR-142-3p is related to the pro-inflammatory function of monocyte-derived dendritic cells in SLE.
Yilun Wang, Jun Liang, +6 authors, Jinhua Xu.
Arthritis Res Ther, 2016 Nov 18; 18(1). PMID: 27852285    Free PMC article.
Combining Theoretical and Experimental Techniques to Study Murine Heart Transplant Rejection.
Julia C Arciero, Andrew Maturo, +3 authors, Giorgio Raimondi.
Front Immunol, 2016 Nov 23; 7. PMID: 27872621    Free PMC article.
DNA Methyltransferase Inhibitor Promotes Human CD4+CD25hFOXP3+ Regulatory T Lymphocyte Induction under Suboptimal TCR Stimulation.
Chun-Hao Lu, Cheng-Jang Wu, +6 authors, Ming-Ling Kuo.
Front Immunol, 2016 Nov 24; 7. PMID: 27877174    Free PMC article.
T regulatory cell mediated immunotherapy for solid organ transplantation: A clinical perspective.
Mohammad Afzal Khan.
Mol Med, 2016 Nov 24; 22. PMID: 27878210    Free PMC article.
Foxp3, Regulatory T Cell, and Autoimmune Diseases.
Jin-Hui Tao, Miao Cheng, +3 authors, Xiang-Pei Li.
Inflammation, 2016 Nov 25; 40(1). PMID: 27882473
Review.
Porphyromonas gingivalis suppresses adaptive immunity in periodontitis, atherosclerosis, and Alzheimer's disease.
Ingar Olsen, Martin A Taubman, Sim K Singhrao.
J Oral Microbiol, 2016 Nov 25; 8. PMID: 27882863    Free PMC article.
Review.
Immune Imbalances in Non-Alcoholic Fatty Liver Disease: From General Biomarkers and Neutrophils to Interleukin-17 Axis Activation and New Therapeutic Targets.
Feliciano Chanana Paquissi.
Front Immunol, 2016 Nov 29; 7. PMID: 27891128    Free PMC article.
Review.
The Double Role of p53 in Cancer and Autoimmunity and Its Potential as Therapeutic Target.
Alessandra Fierabracci, Marsha Pellegrino.
Int J Mol Sci, 2016 Nov 30; 17(12). PMID: 27897991    Free PMC article.
Review.
Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation.
Justyna Ogonek, Mateja Kralj Juric, +4 authors, Eva Weissinger.
Front Immunol, 2016 Dec 03; 7. PMID: 27909435    Free PMC article.
Highly Cited. Review.
Live Imaging of Immune Responses in Experimental Models of Multiple Sclerosis.
Barbara Rossi, Gabriela Constantin.
Front Immunol, 2016 Dec 06; 7. PMID: 27917173    Free PMC article.
Review.
Demystifying the cytokine network: Mathematical models point the way.
Penelope A Morel, Robin E C Lee, James R Faeder.
Cytokine, 2016 Dec 07; 98. PMID: 27919524    Free PMC article.
Review.
Infection, Oxidative Stress, and Changes in Circulating Regulatory T Cells of Heart Failure Patients Supported by Continuous-Flow Ventricular Assist Devices.
Nandan K Mondal, Michael A Sobieski, +4 authors, Zhongjun J Wu.
ASAIO J, 2016 Dec 07; 63(2). PMID: 27922883    Free PMC article.
Time-Dependent Regulation of IL-2R α-Chain (CD25) Expression by TCR Signal Strength and IL-2-Induced STAT5 Signaling in Activated Human Blood T Lymphocytes.
Alla N Shatrova, Elena V Mityushova, +4 authors, Irina I Marakhova.
PLoS One, 2016 Dec 10; 11(12). PMID: 27936140    Free PMC article.
Cancer-derived exosomic microRNAs shape the immune system within the tumor microenvironment: State of the art.
Francesca Fanini, Muller Fabbri.
Semin Cell Dev Biol, 2016 Dec 14; 67. PMID: 27956165    Free PMC article.
Review.
Triptolide Upregulates Myocardial Forkhead Helix Transcription Factor p3 Expression and Attenuates Cardiac Hypertrophy.
Yuan-Yuan Ding, Jing-Mei Li, +7 authors, Hai-Gang Zhang.
Front Pharmacol, 2016 Dec 15; 7. PMID: 27965581    Free PMC article.
Regulatory T cells in cancer immunotherapy.
Atsushi Tanaka, Shimon Sakaguchi.
Cell Res, 2016 Dec 21; 27(1). PMID: 27995907    Free PMC article.
Highly Cited. Review.
Cytokines and metabolic factors regulate tumoricidal T-cell function during cancer immunotherapy.
Adam J Adler, Payal Mittal, +3 authors, Anthony T Vella.
Immunotherapy, 2016 Dec 22; 9(1). PMID: 28000531    Free PMC article.
Review.
The PD1:PD-L1/2 Pathway from Discovery to Clinical Implementation.
Kankana Bardhan, Theodora Anagnostou, Vassiliki A Boussiotis.
Front Immunol, 2016 Dec 27; 7. PMID: 28018338    Free PMC article.
Highly Cited. Review.
Allorecognition by T Lymphocytes and Allograft Rejection.
Jose Marino, Joshua Paster, Gilles Benichou.
Front Immunol, 2016 Dec 27; 7. PMID: 28018349    Free PMC article.
Review.
Porphyromonas gingivalis activates NFκB and MAPK pathways in human oral epithelial cells.
Sabine Groeger, Fabian Jarzina, Eugen Domann, Joerg Meyle.
BMC Immunol, 2017 Jan 07; 18(1). PMID: 28056810    Free PMC article.
Methylation of the FOXP3 upstream enhancer as a clinical indicator of defective regulatory T cells in patients with acute coronary syndrome.
Jun Yang, Xiaoyang Yuan, +5 authors, Xiao-Qing Quan.
Am J Transl Res, 2017 Jan 13; 8(12). PMID: 28078003    Free PMC article.
Diversity of immune cell types in multiple sclerosis and its animal model: Pathological and therapeutic implications.
Yun Cheng, Li Sun, +5 authors, Tao Jin.
J Neurosci Res, 2017 Jan 14; 95(10). PMID: 28084640    Free PMC article.
Review.
Atheroprotective vaccination with MHC-II-restricted ApoB peptides induces peritoneal IL-10-producing CD4 T cells.
Takayuki Kimura, Kevin Tse, +7 authors, Klaus Ley.
Am J Physiol Heart Circ Physiol, 2017 Jan 15; 312(4). PMID: 28087520    Free PMC article.
Direct control of regulatory T cells by keratinocytes.
Mariko Kashiwagi, Junichi Hosoi, +4 authors, Katia Georgopoulos.
Nat Immunol, 2017 Jan 17; 18(3). PMID: 28092372    Free PMC article.
Neural regulation of immunity: molecular mechanisms and clinical translation.
Valentin A Pavlov, Kevin J Tracey.
Nat Neurosci, 2017 Jan 17; 20(2). PMID: 28092663
Highly Cited. Review.
Differences in Peripheral Blood Lymphocytes between Brand-Name and Generic Tacrolimus Used in Stable Liver Transplant Recipients.
Jong Man Kim, Choon Hyuck David Kwon, +5 authors, Suk-Koo Lee.
Med Princ Pract, 2017 Jan 17; 26(3). PMID: 28092916    Free PMC article.
Increased Foxp3+Helios+ Regulatory T Cells and Decreased Acute Graft-versus-Host Disease after Allogeneic Bone Marrow Transplantation in Patients Receiving Sirolimus and RGI-2001, an Activator of Invariant Natural Killer T Cells.
Yi-Bin Chen, Yvonne A Efebera, +13 authors, Jack D Bui.
Biol Blood Marrow Transplant, 2017 Jan 21; 23(4). PMID: 28104514    Free PMC article.
Narcolepsy Type 1 Is Associated with a Systemic Increase and Activation of Regulatory T Cells and with a Systemic Activation of Global T Cells.
Michel Lecendreux, Guillaume Churlaud, +5 authors, Michelle Rosenzwajg.
PLoS One, 2017 Jan 21; 12(1). PMID: 28107375    Free PMC article.
Skin-derived TSLP systemically expands regulatory T cells.
Theresa M Leichner, Atsushi Satake, +9 authors, Taku Kambayashi.
J Autoimmun, 2017 Jan 28; 79. PMID: 28126203    Free PMC article.
Immunologic characteristics of HIV-infected individuals who make broadly neutralizing antibodies.
Persephone Borrow, M Anthony Moody.
Immunol Rev, 2017 Jan 31; 275(1). PMID: 28133804    Free PMC article.
Review.
Alterations of p11 in brain tissue and peripheral blood leukocytes in Parkinson's disease.
Holly Green, Xiaoqun Zhang, +6 authors, Per Svenningsson.
Proc Natl Acad Sci U S A, 2017 Feb 01; 114(10). PMID: 28137881    Free PMC article.
PD-1 modulates regulatory T-cell homeostasis during low-dose interleukin-2 therapy.
Takeru Asano, Yusuke Meguri, +17 authors, Ken-Ichi Matsuoka.
Blood, 2017 Feb 06; 129(15). PMID: 28151427    Free PMC article.
Highly Cited.
Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction.
Vimal Ramjee, Deqiang Li, +14 authors, Jonathan A Epstein.
J Clin Invest, 2017 Feb 07; 127(3). PMID: 28165342    Free PMC article.
HIF-1α inhibitor echinomycin reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect.
Yushi Yao, Lei Wang, Jihao Zhou, Xinyou Zhang.
J Transl Med, 2017 Feb 12; 15(1). PMID: 28183349    Free PMC article.
Novel Immunotherapies for Autoimmune Hepatitis.
Shamir Cassim, Marc Bilodeau, Catherine Vincent, Pascal Lapierre.
Front Pediatr, 2017 Feb 12; 5. PMID: 28184367    Free PMC article.
Review.
Concise Review: Fat and Furious: Harnessing the Full Potential of Adipose-Derived Stromal Vascular Fraction.
Jordan A Dykstra, Tiffany Facile, +4 authors, Daniel J Kota.
Stem Cells Transl Med, 2017 Feb 12; 6(4). PMID: 28186685    Free PMC article.
Review.
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy.
Padmanee Sharma, Siwen Hu-Lieskovan, Jennifer A Wargo, Antoni Ribas.
Cell, 2017 Feb 12; 168(4). PMID: 28187290    Free PMC article.
Highly Cited. Review.
Deregulation of Regulatory T Cells in Acute-on-Chronic Liver Failure: A Rat Model.
Shunlan Ni, Shanshan Li, +4 authors, Mingqin Lu.
Mediators Inflamm, 2017 Feb 15; 2017. PMID: 28194045    Free PMC article.
CD4+  CD25+  GARP+ regulatory T cells display a compromised suppressive function in patients with dilated cardiomyopathy.
Yuzhen Wei, Kunwu Yu, +9 authors, Qiutang Zeng.
Immunology, 2017 Feb 17; 151(3). PMID: 28207945    Free PMC article.
Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance.
Kenneth S K Tung, Jessica Harakal, +15 authors, Erwin Goldberg.
J Clin Invest, 2017 Feb 22; 127(3). PMID: 28218625    Free PMC article.
Single CD28 stimulation induces stable and polyclonal expansion of human regulatory T cells.
Xuehui He, Ruben L Smeets, +3 authors, Hans J P M Koenen.
Sci Rep, 2017 Feb 23; 7. PMID: 28223693    Free PMC article.
Analysis of the T Cell Response to Zika Virus and Identification of a Novel CD8+ T Cell Epitope in Immunocompetent Mice.
Ryan D Pardy, Maaran M Rajah, +3 authors, Martin J Richer.
PLoS Pathog, 2017 Feb 24; 13(2). PMID: 28231312    Free PMC article.
Highly Cited.
Targeting CD38 Suppresses Induction and Function of T Regulatory Cells to Mitigate Immunosuppression in Multiple Myeloma.
Xiaoyan Feng, Li Zhang, +6 authors, Kenneth C Anderson.
Clin Cancer Res, 2017 Mar 03; 23(15). PMID: 28249894    Free PMC article.
Highly Cited.
Role of T Lymphocytes in Type 2 Diabetes and Diabetes-Associated Inflammation.
Chang Xia, Xiaoquan Rao, Jixin Zhong.
J Diabetes Res, 2017 Mar 03; 2017. PMID: 28251163    Free PMC article.
Review.
Exposure to sequestered self-antigens in vivo is not sufficient for the induction of autoimmune diabetes.
Nobuyuki Ono, Kiichi Murakami, +7 authors, Salim Dhanji.
PLoS One, 2017 Mar 04; 12(3). PMID: 28257518    Free PMC article.
Growth Arrest-Specific 6 Enhances the Suppressive Function of CD4+CD25+ Regulatory T Cells Mainly through Axl Receptor.
Guang-Ju Zhao, Jia-Yi Zheng, +7 authors, Zhong-Qiu Lu.
Mediators Inflamm, 2017 Mar 09; 2017. PMID: 28270700    Free PMC article.
A Novel Model on DST-Induced Transplantation Tolerance by the Transfer of Self-Specific Donor tTregs to a Haplotype-Matched Organ Recipient.
Angelica Maria Mohr Gregoriussen, Henrik Georg Bohr.
Front Immunol, 2017 Mar 09; 8. PMID: 28270810    Free PMC article.
CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis.
Christian Barthels, Ana Ogrinc, +12 authors, Thomas Brocker.
Nat Commun, 2017 Mar 10; 8. PMID: 28276457    Free PMC article.
ALS patients' regulatory T lymphocytes are dysfunctional, and correlate with disease progression rate and severity.
David R Beers, Weihua Zhao, +8 authors, Stanley H Appel.
JCI Insight, 2017 Mar 16; 2(5). PMID: 28289705    Free PMC article.
ICOSL expression in human bone marrow-derived mesenchymal stem cells promotes induction of regulatory T cells.
Hyun-Joo Lee, Si-Na Kim, +2 authors, Sun U Song.
Sci Rep, 2017 Mar 16; 7. PMID: 28290526    Free PMC article.
T Lymphocytes and Inflammatory Mediators in the Interplay between Brain and Blood in Alzheimer's Disease: Potential Pools of New Biomarkers.
Anna Mietelska-Porowska, Urszula Wojda.
J Immunol Res, 2017 Mar 16; 2017. PMID: 28293644    Free PMC article.
Review.
miRNAs: novel regulators of autoimmunity-mediated pancreatic β-cell destruction in type 1 diabetes.
Ying Zheng, Zhen Wang, Zhiguang Zhou.
Cell Mol Immunol, 2017 Mar 21; 14(6). PMID: 28317889    Free PMC article.
Review.
Tetrandrine, an agonist of aryl hydrocarbon receptor, reciprocally modulates the activities of STAT3 and STAT5 to suppress Th17 cell differentiation.
Xusheng Yuan, Yannong Dou, +2 authors, Yue Dai.
J Cell Mol Med, 2017 Mar 24; 21(9). PMID: 28332288    Free PMC article.
IL-1β induced HIF-1α inhibits the differentiation of human FOXP3+ T cells.
Lea M Feldhoff, Cesar M Rueda, +4 authors, Jan Rupp.
Sci Rep, 2017 Mar 30; 7(1). PMID: 28352109    Free PMC article.
Mechanisms and consequences of intestinal dysbiosis.
G Adrienne Weiss, Thierry Hennet.
Cell Mol Life Sci, 2017 Mar 30; 74(16). PMID: 28352996
Highly Cited. Review.
The role of metabolic reprogramming in T cell fate and function.
Nikolaos Patsoukis, Kankana Bardhan, +4 authors, Vassiliki A Boussiotis.
Curr Trends Immunol, 2016 Jan 01; 17. PMID: 28356677    Free PMC article.
ATVB Distinguished Scientist Award: How Costimulatory and Coinhibitory Pathways Shape Atherosclerosis.
Klaus Ley, Norbert Gerdes, Holger Winkels.
Arterioscler Thromb Vasc Biol, 2017 Apr 01; 37(5). PMID: 28360089    Free PMC article.
Review.
Proteomic Analysis of Regulatory T Cells Reveals the Importance of Themis1 in the Control of Their Suppressive Function.
Fanny Duguet, Marie Locard-Paulet, +7 authors, Abdelhadi Saoudi.
Mol Cell Proteomics, 2017 Apr 05; 16(8). PMID: 28373295    Free PMC article.
TET Methylcytosine Oxidases in T Cell and B Cell Development and Function.
Ageliki Tsagaratou, Chan-Wang J Lio, Xiaojing Yue, Anjana Rao.
Front Immunol, 2017 Apr 15; 8. PMID: 28408905    Free PMC article.
Review.
Update on Biomarkers to Monitor Clinical Efficacy Response During and Post Treatment in Allergen Immunotherapy.
Lubna Kouser, Jasper Kappen, Ross P Walton, Mohamed H Shamji.
Curr Treat Options Allergy, 2017 Apr 18; 4(1). PMID: 28413769    Free PMC article.
Review.
In vivo reprogramming of immune cells: Technologies for induction of antigen-specific tolerance.
Ryan M Pearson, Liam M Casey, +2 authors, Lonnie D Shea.
Adv Drug Deliv Rev, 2017 Apr 18; 114. PMID: 28414079    Free PMC article.
Review.
Interleukin-2-regulatory T cell axis critically regulates maintenance of hematopoietic stem cells.
Sabrina Giampaolo, Gabriela Wójcik, Edgar Serfling, Amiya K Patra.
Oncotarget, 2017 Apr 19; 8(18). PMID: 28415569    Free PMC article.
Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells.
Garima Garg, Eirini Nikolouli, +13 authors, Jochen Huehn.
Oncotarget, 2017 Apr 19; 8(22). PMID: 28415767    Free PMC article.
Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients.
A Schiza, J Wenthe, +5 authors, G Ullenhag.
J Transl Med, 2017 Apr 22; 15(1). PMID: 28427434    Free PMC article.
The Protective Role of Type I Interferons in the Gastrointestinal Tract.
Kevin P Kotredes, Brianna Thomas, Ana M Gamero.
Front Immunol, 2017 Apr 22; 8. PMID: 28428788    Free PMC article.
Review.
Diabetic Cardiomyopathy: An Immunometabolic Perspective.
Paras K Mishra, Wei Ying, +3 authors, Sushil K Mahata.
Front Endocrinol (Lausanne), 2017 Apr 26; 8. PMID: 28439258    Free PMC article.
Review.
The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis.
Chen Yang, Xiao-Ru Huang, +2 authors, Hui-Yao Lan.
Sci Rep, 2017 May 05; 7(1). PMID: 28469165    Free PMC article.
Oroxylin A inhibits the generation of Tregs in non-small cell lung cancer.
Le Shen, Lu-Lu Zhang, +6 authors, Shuai Zhang.
Oncotarget, 2017 May 05; 8(30). PMID: 28472762    Free PMC article.
Foxp3+ regulatory T cells maintain the bone marrow microenvironment for B cell lymphopoiesis.
Antonio Pierini, Hidekazu Nishikii, +11 authors, Robert S Negrin.
Nat Commun, 2017 May 10; 8. PMID: 28485401    Free PMC article.
mTORC1 regulates mannose-6-phosphate receptor transport and T-cell vulnerability to regulatory T cells by controlling kinesin KIF13A.
Khawaja Ashfaque Ahmed, Jim Xiang.
Cell Discov, 2017 May 13; 3. PMID: 28496990    Free PMC article.
Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells.
Rodrigo Vazquez-Lombardi, Claudia Loetsch, +8 authors, Daniel Christ.
Nat Commun, 2017 May 13; 8. PMID: 28497796    Free PMC article.
Stabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells.
Masahiro Okada, Mitsuhiro Kanamori, +2 authors, Akihiko Yoshimura.
Epigenetics Chromatin, 2017 May 16; 10. PMID: 28503202    Free PMC article.
Interleukin-10-producing LAG3+ regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis.
Shinichiro Nakachi, Shuji Sumitomo, +11 authors, Keishi Fujio.
Arthritis Res Ther, 2017 May 18; 19(1). PMID: 28511719    Free PMC article.
Mechanisms of Immune Tolerance in Leukemia and Lymphoma.
Emily K Curran, James Godfrey, Justin Kline.
Trends Immunol, 2017 May 18; 38(7). PMID: 28511816    Free PMC article.
Review.
Ubiquitin enzymes in the regulation of immune responses.
Petra Ebner, Gijs A Versteeg, Fumiyo Ikeda.
Crit Rev Biochem Mol Biol, 2017 May 20; 52(4). PMID: 28524749    Free PMC article.
Review.
Bio-synthetic materials for immunomodulation of islet transplants.
Greg A Foster, Andrés J García.
Adv Drug Deliv Rev, 2017 May 24; 114. PMID: 28532691    Free PMC article.
Review.
Effector and Regulatory T Cell Trafficking in Corneal Allograft Rejection.
Afsaneh Amouzegar, Sunil K Chauhan.
Mediators Inflamm, 2017 May 26; 2017. PMID: 28539707    Free PMC article.
Review.
Increased serum level of soluble interleukin-2 receptor is associated with a worse response of metastatic clear cell renal cell carcinoma to interferon alpha and sequential VEGF-targeting therapy.
Akinori Nukui, Akinori Masuda, +3 authors, Takao Kamai.
BMC Cancer, 2017 May 27; 17(1). PMID: 28545581    Free PMC article.
Membrane-bound Dickkopf-1 in Foxp3+ regulatory T cells suppresses T-cell-mediated autoimmune colitis.
Wook-Jin Chae, Jong-Hyun Park, +3 authors, Alfred L M Bothwell.
Immunology, 2017 May 31; 152(2). PMID: 28556921    Free PMC article.
Use of immune modulation by human adipose-derived mesenchymal stem cells to treat experimental arthritis in mice.
Li Zhang, Xiao-Yan Wang, +12 authors, Yi-Fei Wang.
Am J Transl Res, 2017 Jun 01; 9(5). PMID: 28560007    Free PMC article.
Tregs restrain dendritic cell autophagy to ameliorate autoimmunity.
Themis Alissafi, Aggelos Banos, +8 authors, Panayotis Verginis.
J Clin Invest, 2017 Jun 06; 127(7). PMID: 28581446    Free PMC article.
Immunoregulatory effects of the traditional Dai prescription Yajieshaba on food allergic mice.
Guangyuan Zhang, Xiaohua Duan, +3 authors, Jin Zheng.
Exp Ther Med, 2017 Jun 08; 13(6). PMID: 28587391    Free PMC article.
Association of increased Treg and Th17 with pathogenesis of moyamoya disease.
Leihua Weng, Xiang Cao, +12 authors, Yun Xu.
Sci Rep, 2017 Jun 10; 7(1). PMID: 28596558