Journal Article
. 2009 Feb;27(8).
doi: 10.1200/JCO.2008.18.1370.

Supervised risk predictor of breast cancer based on intrinsic subtypes

Joel S Parker 1 Michael Mullins  Maggie C U Cheang  Samuel Leung  David Voduc  Tammi Vickery  Sherri Davies  Christiane Fauron  Xiaping He  Zhiyuan Hu  John F Quackenbush  Inge J Stijleman  Juan Palazzo  J S Marron  Andrew B Nobel  Elaine Mardis  Torsten O Nielsen  Matthew J Ellis  Charles M Perou  Philip S Bernard  
Affiliations
  • PMID: 19204204
  •     26 References
  •     1547 citations

Abstract

Unlabelled: PURPOSE To improve on current standards for breast cancer prognosis and prediction of chemotherapy benefit by developing a risk model that incorporates the gene expression-based "intrinsic" subtypes luminal A, luminal B, HER2-enriched, and basal-like. METHODS A 50-gene subtype predictor was developed using microarray and quantitative reverse transcriptase polymerase chain reaction data from 189 prototype samples. Test sets from 761 patients (no systemic therapy) were evaluated for prognosis, and 133 patients were evaluated for prediction of pathologic complete response (pCR) to a taxane and anthracycline regimen.

Results: The intrinsic subtypes as discrete entities showed prognostic significance (P = 2.26E-12) and remained significant in multivariable analyses that incorporated standard parameters (estrogen receptor status, histologic grade, tumor size, and node status). A prognostic model for node-negative breast cancer was built using intrinsic subtype and clinical information. The C-index estimate for the combined model (subtype and tumor size) was a significant improvement on either the clinicopathologic model or subtype model alone. The intrinsic subtype model predicted neoadjuvant chemotherapy efficacy with a negative predictive value for pCR of 97%. CONCLUSION Diagnosis by intrinsic subtype adds significant prognostic and predictive information to standard parameters for patients with breast cancer. The prognostic properties of the continuous risk score will be of value for the management of node-negative breast cancers. The subtypes and risk score can also be used to assess the likelihood of efficacy from neoadjuvant chemotherapy.

Molecular portraits of human breast tumours.
C M Perou, T Sørlie, +15 authors, D Botstein.
Nature, 2000 Aug 30; 406(6797). PMID: 10963602
Highly Cited.
Nomograms to predict pathologic complete response and metastasis-free survival after preoperative chemotherapy for breast cancer.
Roman Rouzier, Lajos Pusztai, +13 authors, Gabriel N Hortobagyi.
J Clin Oncol, 2005 Nov 19; 23(33). PMID: 16293864
Gene expression profiling predicts clinical outcome of breast cancer.
Laura J van 't Veer, Hongyue Dai, +13 authors, Stephen H Friend.
Nature, 2002 Feb 02; 415(6871). PMID: 11823860
Highly Cited.
Diagnosis of multiple cancer types by shrunken centroids of gene expression.
Robert Tibshirani, Trevor Hastie, Balasubramanian Narasimhan, Gilbert Chu.
Proc Natl Acad Sci U S A, 2002 May 16; 99(10). PMID: 12011421    Free PMC article.
Highly Cited.
A prediction-based resampling method for estimating the number of clusters in a dataset.
Sandrine Dudoit, Jane Fridlyand.
Genome Biol, 2002 Aug 20; 3(7). PMID: 12184810    Free PMC article.
A gene-expression signature as a predictor of survival in breast cancer.
Marc J van de Vijver, Yudong D He, +18 authors, René Bernards.
N Engl J Med, 2002 Dec 20; 347(25). PMID: 12490681
Highly Cited.
Statistical methods for identifying differentially expressed genes in DNA microarrays.
John D Storey, Robert Tibshirani.
Methods Mol Biol, 2003 Apr 25; 224. PMID: 12710672
Highly Cited.
Repeated observation of breast tumor subtypes in independent gene expression data sets.
Therese Sorlie, Robert Tibshirani, +13 authors, David Botstein.
Proc Natl Acad Sci U S A, 2003 Jun 28; 100(14). PMID: 12829800    Free PMC article.
Highly Cited.
Cluster analysis and display of genome-wide expression patterns.
M B Eisen, P T Spellman, P O Brown, D Botstein.
Proc Natl Acad Sci U S A, 1998 Dec 09; 95(25). PMID: 9843981    Free PMC article.
Highly Cited.
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer.
Soonmyung Paik, Steven Shak, +12 authors, Norman Wolmark.
N Engl J Med, 2004 Dec 14; 351(27). PMID: 15591335
Highly Cited.
Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer.
Yixin Wang, Jan G M Klijn, +11 authors, John A Foekens.
Lancet, 2005 Feb 22; 365(9460). PMID: 15721472
Highly Cited.
Gene expression profiling of breast cancer: a new tumor marker.
Laura J van't Veer, Soonmyung Paik, Daniel F Hayes.
J Clin Oncol, 2005 Mar 10; 23(8). PMID: 15755970
Review.
Classification of microarrays to nearest centroids.
Alan R Dabney.
Bioinformatics, 2005 Sep 22; 21(22). PMID: 16174683
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications.
T Sørlie, C M Perou, +14 authors, A L Børresen-Dale.
Proc Natl Acad Sci U S A, 2001 Sep 13; 98(19). PMID: 11553815    Free PMC article.
Highly Cited.
Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis.
Christos Sotiriou, Pratyaksha Wirapati, +17 authors, Mauro Delorenzi.
J Natl Cancer Inst, 2006 Feb 16; 98(4). PMID: 16478745
Highly Cited.
The molecular portraits of breast tumors are conserved across microarray platforms.
Zhiyuan Hu, Cheng Fan, +28 authors, Charles M Perou.
BMC Genomics, 2006 Apr 29; 7. PMID: 16643655    Free PMC article.
Highly Cited.
Classification and risk stratification of invasive breast carcinomas using a real-time quantitative RT-PCR assay.
Laurent Perreard, Cheng Fan, +18 authors, Philip S Bernard.
Breast Cancer Res, 2006 Apr 22; 8(2). PMID: 16626501    Free PMC article.
Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer.
Soonmyung Paik, Gong Tang, +11 authors, Norman Wolmark.
J Clin Oncol, 2006 May 25; 24(23). PMID: 16720680
Highly Cited.
Concordance among gene-expression-based predictors for breast cancer.
Cheng Fan, Daniel S Oh, +5 authors, Charles M Perou.
N Engl J Med, 2006 Aug 11; 355(6). PMID: 16899776
Highly Cited.
Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer.
Anna V Ivshina, Joshy George, +12 authors, Lance D Miller.
Cancer Res, 2006 Nov 03; 66(21). PMID: 17079448
Highly Cited.
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes.
Richard M Neve, Koei Chin, +24 authors, Joe W Gray.
Cancer Cell, 2006 Dec 13; 10(6). PMID: 17157791    Free PMC article.
Highly Cited.
Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer.
Lyndsay N Harris, Fanglei You, +12 authors, Eric P Winer.
Clin Cancer Res, 2007 Feb 24; 13(4). PMID: 17317830
Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade.
Sherene Loi, Benjamin Haibe-Kains, +14 authors, Christos Sotiriou.
J Clin Oncol, 2007 Apr 03; 25(10). PMID: 17401012
Highly Cited.
Agreement in breast cancer classification between microarray and quantitative reverse transcription PCR from fresh-frozen and formalin-fixed, paraffin-embedded tissues.
Michael Mullins, Laurent Perreard, +7 authors, Philip S Bernard.
Clin Chem, 2007 May 26; 53(7). PMID: 17525107
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors.
Jason I Herschkowitz, Karl Simin, +23 authors, Charles M Perou.
Genome Biol, 2007 May 12; 8(5). PMID: 17493263    Free PMC article.
Highly Cited.
Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer.
Kenneth R Hess, Keith Anderson, +14 authors, Lajos Pusztai.
J Clin Oncol, 2006 Aug 10; 24(26). PMID: 16896004
Highly Cited.
PIK3CA and PIK3CB inhibition produce synthetic lethality when combined with estrogen deprivation in estrogen receptor-positive breast cancer.
Robert J Crowder, Chanpheng Phommaly, +14 authors, Matthew J Ellis.
Cancer Res, 2009 Apr 16; 69(9). PMID: 19366795    Free PMC article.
Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer.
Maggie C U Cheang, Stephen K Chia, +10 authors, Torsten O Nielsen.
J Natl Cancer Inst, 2009 May 14; 101(10). PMID: 19436038    Free PMC article.
Highly Cited.
Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer.
Brian Bierie, Christine H Chung, +6 authors, Harold L Moses.
J Clin Invest, 2009 May 20; 119(6). PMID: 19451693    Free PMC article.
Challenges in studying the etiology of breast cancer subtypes.
Melissa A Troester, Theresa Swift-Scanlan.
Breast Cancer Res, 2009 Jul 29; 11(3). PMID: 19635173    Free PMC article.
Genetic characterization of breast cancer and implications for clinical management.
Felipe C Geyer, Maria A Lopez-Garcia, Maryou B Lambros, Jorge S Reis-Filho.
J Cell Mol Med, 2009 Sep 17; 13(10). PMID: 19754664    Free PMC article.
Review.
8p22 MTUS1 gene product ATIP3 is a novel anti-mitotic protein underexpressed in invasive breast carcinoma of poor prognosis.
Sylvie Rodrigues-Ferreira, Anne Di Tommaso, +14 authors, Clara Nahmias.
PLoS One, 2009 Oct 02; 4(10). PMID: 19794912    Free PMC article.
Histological and molecular types of breast cancer: is there a unifying taxonomy?
Britta Weigelt, Jorge S Reis-Filho.
Nat Rev Clin Oncol, 2009 Nov 28; 6(12). PMID: 19942925
Highly Cited. Review.
Gene expression pathway analysis to predict response to neoadjuvant docetaxel and capecitabine for breast cancer.
Larissa A Korde, Lara Lusa, +7 authors, Jo Anne Zujewski.
Breast Cancer Res Treat, 2009 Dec 17; 119(3). PMID: 20012355    Free PMC article.
Gene expression profiling of breast cancer.
Lajos Pusztai.
Breast Cancer Res, 2010 Jan 20; 11 Suppl 3. PMID: 20030862    Free PMC article.
Adjuvant therapy of triple negative breast cancer.
Edith A Perez, Alvaro Moreno-Aspitia, E Aubrey Thompson, Cathy A Andorfer.
Breast Cancer Res Treat, 2010 Jan 23; 120(2). PMID: 20094772    Free PMC article.
Review.
Relationship between plasma estradiol levels and estrogen-responsive gene expression in estrogen receptor-positive breast cancer in postmenopausal women.
Anita K Dunbier, Helen Anderson, +11 authors, Mitch Dowsett.
J Clin Oncol, 2010 Feb 04; 28(7). PMID: 20124184    Free PMC article.
Gene expression in nontumoral liver tissue and recurrence-free survival in hepatitis C virus-positive hepatocellular carcinoma.
Masato Tsuchiya, Joel S Parker, +3 authors, Ivan Rusyn.
Mol Cancer, 2010 Apr 13; 9. PMID: 20380719    Free PMC article.
Genome remodelling in a basal-like breast cancer metastasis and xenograft.
Li Ding, Matthew J Ellis, +66 authors, Elaine R Mardis.
Nature, 2010 Apr 16; 464(7291). PMID: 20393555    Free PMC article.
Highly Cited.
A growing family: adding mutated Erbb4 as a novel cancer target.
Udo Rudloff, Yardena Samuels.
Cell Cycle, 2010 Apr 21; 9(8). PMID: 20404484    Free PMC article.
Gene-expression-based prognostic assays for breast cancer.
Chungyeul Kim, Soonmyung Paik.
Nat Rev Clin Oncol, 2010 May 05; 7(6). PMID: 20440284
Review.
Histological types of breast cancer: how special are they?
Britta Weigelt, Felipe C Geyer, Jorge S Reis-Filho.
Mol Oncol, 2010 May 11; 4(3). PMID: 20452298    Free PMC article.
Highly Cited. Review.
High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer.
Johan Staaf, Göran Jönsson, +10 authors, Ake Borg.
Breast Cancer Res, 2010 May 13; 12(3). PMID: 20459607    Free PMC article.
Tumor metabolism and blood flow as assessed by positron emission tomography varies by tumor subtype in locally advanced breast cancer.
Jennifer M Specht, Brenda F Kurland, +9 authors, David A Mankoff.
Clin Cancer Res, 2010 May 13; 16(10). PMID: 20460489    Free PMC article.
Molecular basis for therapy resistance.
Per E Lønning.
Mol Oncol, 2010 May 15; 4(3). PMID: 20466604    Free PMC article.
Review.
PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer.
Sherene Loi, Benjamin Haibe-Kains, +17 authors, Christos Sotiriou.
Proc Natl Acad Sci U S A, 2010 May 19; 107(22). PMID: 20479250    Free PMC article.
Highly Cited.
Triple-negative breast cancer: present challenges and new perspectives.
Franca Podo, Lutgarde M C Buydens, +16 authors, FEMME Consortium.
Mol Oncol, 2010 Jun 12; 4(3). PMID: 20537966    Free PMC article.
Highly Cited. Review.
Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53.
Chad Deisenroth, Aaron R Thorner, +2 authors, Yanping Zhang.
Mol Cell Biol, 2010 Jun 16; 30(16). PMID: 20547751    Free PMC article.
Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns.
Karolina Holm, Cecilia Hegardt, +5 authors, Markus Ringnér.
Breast Cancer Res, 2010 Jun 23; 12(3). PMID: 20565864    Free PMC article.
Highly Cited.
Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer.
Chad J Creighton, Xiaoyong Fu, +11 authors, Rachel Schiff.
Breast Cancer Res, 2010 Jun 24; 12(3). PMID: 20569503    Free PMC article.
Highly Cited.
Molecular diversity in ductal carcinoma in situ (DCIS) and early invasive breast cancer.
Aslaug Aamodt Muggerud, Michael Hallett, +8 authors, Fredrik Wärnberg.
Mol Oncol, 2010 Jul 29; 4(4). PMID: 20663721    Free PMC article.
Ferroportin and iron regulation in breast cancer progression and prognosis.
Zandra K Pinnix, Lance D Miller, +9 authors, Frank M Torti.
Sci Transl Med, 2010 Aug 06; 2(43). PMID: 20686179    Free PMC article.
Highly Cited.
Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool.
Y H Chia, M J Ellis, C X Ma.
Br J Cancer, 2010 Aug 12; 103(6). PMID: 20700118    Free PMC article.
Review.
Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density.
Vilde D Haakensen, Margarethe Biong, +12 authors, Aslaug Helland.
Breast Cancer Res, 2010 Aug 31; 12(4). PMID: 20799965    Free PMC article.
Microarray data analysis in neoadjuvant biomarker studies in estrogen receptor-positive breast cancer.
Jingqin Luo, Matthew J Ellis.
Breast Cancer Res, 2010 Sep 02; 12(4). PMID: 20804563    Free PMC article.
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer.
Aleix Prat, Joel S Parker, +5 authors, Charles M Perou.
Breast Cancer Res, 2010 Sep 04; 12(5). PMID: 20813035    Free PMC article.
Highly Cited.
Poly (ADP-ribose) polymerase as a novel therapeutic target in cancer.
Christina M Annunziata, Joyce O'Shaughnessy.
Clin Cancer Res, 2010 Sep 09; 16(18). PMID: 20823142    Free PMC article.
Review.
Allele-specific copy number analysis of tumors.
Peter Van Loo, Silje H Nordgard, +10 authors, Vessela N Kristensen.
Proc Natl Acad Sci U S A, 2010 Sep 15; 107(39). PMID: 20837533    Free PMC article.
Highly Cited.
A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptor-positive breast cancer.
Torsten O Nielsen, Joel S Parker, +12 authors, Matthew J Ellis.
Clin Cancer Res, 2010 Sep 15; 16(21). PMID: 20837693    Free PMC article.
Highly Cited.
Minireview: Basal-like breast cancer: from molecular profiles to targeted therapies.
Daniel J Toft, Vincent L Cryns.
Mol Endocrinol, 2010 Sep 24; 25(2). PMID: 20861225    Free PMC article.
Review.
DNA repair and personalized breast cancer therapy.
Shu-Xia Li, Ashley Sjolund, Lyndsay Harris, Joann B Sweasy.
Environ Mol Mutagen, 2010 Sep 28; 51(8-9). PMID: 20872853    Free PMC article.
Review.
Triple-negative breast cancer: disease entity or title of convenience?
Lisa Carey, Eric Winer, +2 authors, Luca Gianni.
Nat Rev Clin Oncol, 2010 Sep 30; 7(12). PMID: 20877296
Highly Cited. Review.
DNA methylation epigenotypes in breast cancer molecular subtypes.
Naiara G Bediaga, Amelia Acha-Sagredo, +13 authors, Marian M de Pancorbo.
Breast Cancer Res, 2010 Oct 06; 12(5). PMID: 20920229    Free PMC article.
Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response.
Josie Ursini-Siegel, Sean Cory, +15 authors, William J Muller.
Cancer Res, 2010 Oct 07; 70(20). PMID: 20924104    Free PMC article.
Genome profiling of ERBB2-amplified breast cancers.
Fabrice Sircoulomb, Ismahane Bekhouche, +13 authors, Max Chaffanet.
BMC Cancer, 2010 Oct 12; 10. PMID: 20932292    Free PMC article.
Potential tumor suppressor role for the c-Myb oncogene in luminal breast cancer.
Aaron R Thorner, Joel S Parker, Katherine A Hoadley, Charles M Perou.
PLoS One, 2010 Oct 16; 5(10). PMID: 20949095    Free PMC article.
Breast cancer assessment tools and optimizing adjuvant therapy.
Catherine Oakman, Libero Santarpia, Angelo Di Leo.
Nat Rev Clin Oncol, 2010 Oct 27; 7(12). PMID: 20975745
Review.
Treatment options for patients with triple-negative breast cancer.
Rafael Santana-Davila, Edith A Perez.
J Hematol Oncol, 2010 Oct 29; 3. PMID: 20979652    Free PMC article.
Review.
Systems biology and genomics of breast cancer.
Charles M Perou, Anne-Lise Børresen-Dale.
Cold Spring Harb Perspect Biol, 2010 Nov 05; 3(2). PMID: 21047916    Free PMC article.
Review.
Histological, molecular and functional subtypes of breast cancers.
Gautam K Malhotra, Xiangshan Zhao, Hamid Band, Vimla Band.
Cancer Biol Ther, 2010 Nov 09; 10(10). PMID: 21057215    Free PMC article.
Review.
Identification of a low-risk subgroup of HER-2-positive breast cancer by the 70-gene prognosis signature.
M Knauer, F Cardoso, +4 authors, L J van 't Veer.
Br J Cancer, 2010 Nov 18; 103(12). PMID: 21081926    Free PMC article.
Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2.
Juha K Rantala, Henrik Edgren, +9 authors, Olli Kallioniemi.
Neoplasia, 2010 Nov 18; 12(11). PMID: 21082043    Free PMC article.
Predicting prognosis of breast cancer with gene signatures: are we lost in a sea of data?
Takayuki Iwamoto, Lajos Pusztai.
Genome Med, 2010 Nov 26; 2(11). PMID: 21092148    Free PMC article.
Breast carcinomas arising at a young age: unique biology or a surrogate for aggressive intrinsic subtypes?
Carey K Anders, Cheng Fan, +4 authors, Charles M Perou.
J Clin Oncol, 2010 Dec 01; 29(1). PMID: 21115855    Free PMC article.
Interactions with fibroblasts are distinct in Basal-like and luminal breast cancers.
J Terese Camp, Fathi Elloumi, +5 authors, Melissa A Troester.
Mol Cancer Res, 2010 Dec 07; 9(1). PMID: 21131600    Free PMC article.
Deconstructing the molecular portraits of breast cancer.
Aleix Prat, Charles M Perou.
Mol Oncol, 2010 Dec 15; 5(1). PMID: 21147047    Free PMC article.
Highly Cited. Review.
Phase II study of bortezomib and pegylated liposomal doxorubicin in the treatment of metastatic breast cancer.
William J Irvin, Robert Z Orlowski, +7 authors, E Claire Dees.
Clin Breast Cancer, 2010 Dec 15; 10(6). PMID: 21147690    Free PMC article.
Different gene expressions are associated with the different molecular subtypes of inflammatory breast cancer.
Takayuki Iwamoto, Giampaolo Bianchini, +13 authors, Naoto T Ueno.
Breast Cancer Res Treat, 2010 Dec 15; 125(3). PMID: 21153052    Free PMC article.
Basal-like breast cancers: the phenotypic disparity between the cancer-initiating cells and tumor histology.
Afshin Raouf.
Breast Cancer Res, 2010 Dec 22; 12(6). PMID: 21172068    Free PMC article.
Molecular profiling currently offers no more than tumour morphology and basic immunohistochemistry.
Britta Weigelt, Jorge S Reis-Filho.
Breast Cancer Res, 2011 Jan 05; 12 Suppl 4. PMID: 21172089    Free PMC article.
Cisplatin as neoadjuvant chemotherapy in triple negative breast cancer: Exciting early results.
Arun Kumar Goel, Malay Nandy, Gopal Sharma.
Indian J Med Paediatr Oncol, 2011 Jan 06; 31(3). PMID: 21206711    Free PMC article.
Building prognostic models for breast cancer patients using clinical variables and hundreds of gene expression signatures.
Cheng Fan, Aleix Prat, +4 authors, Charles M Perou.
BMC Med Genomics, 2011 Jan 11; 4. PMID: 21214954    Free PMC article.
Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure.
Laurent Sansregret, Charles Vadnais, +6 authors, Alain Nepveu.
Proc Natl Acad Sci U S A, 2011 Jan 20; 108(5). PMID: 21245318    Free PMC article.
Breast cancer and fertility preservation.
S Samuel Kim, Jennifer Klemp, Carol Fabian.
Fertil Steril, 2011 Jan 29; 95(5). PMID: 21272867    Free PMC article.
Review.
Studying therapy response and resistance in mouse models for BRCA1-deficient breast cancer.
Ewa Malgorzata Michalak, Jos Jonkers.
J Mammary Gland Biol Neoplasia, 2011 Feb 19; 16(1). PMID: 21331759
Review.
Challenges to developing proteomic-based breast cancer diagnostics.
Richard R Drake, Lisa H Cazares, +3 authors, Christine Laronga.
OMICS, 2011 Feb 22; 15(5). PMID: 21332380    Free PMC article.
Review.
The cell of origin of BRCA1 mutation-associated breast cancer: a cautionary tale of gene expression profiling.
Gemma Molyneux, Matthew J Smalley.
J Mammary Gland Biol Neoplasia, 2011 Feb 22; 16(1). PMID: 21336547
Review.
ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium.
Daniel G Holland, Angela Burleigh, +19 authors, Carlos Caldas.
EMBO Mol Med, 2011 Feb 22; 3(3). PMID: 21337521    Free PMC article.
A gene expression signature from human breast cancer cells with acquired hormone independence identifies MYC as a mediator of antiestrogen resistance.
Todd W Miller, Justin M Balko, +9 authors, Carlos L Arteaga.
Clin Cancer Res, 2011 Feb 25; 17(7). PMID: 21346144    Free PMC article.
Integrated analysis of gene expression, CpG island methylation, and gene copy number in breast cancer cells by deep sequencing.
Zhifu Sun, Yan W Asmann, +10 authors, E Aubrey Thompson.
PLoS One, 2011 Mar 03; 6(2). PMID: 21364760    Free PMC article.
Methylated genes in breast cancer: associations with clinical and histopathological features in a familial breast cancer cohort.
Theresa Swift-Scanlan, Russell Vang, +2 authors, Saraswati Sukumar.
Cancer Biol Ther, 2011 Mar 09; 11(10). PMID: 21383541    Free PMC article.
Ribavirin treatment effects on breast cancers overexpressing eIF4E, a biomarker with prognostic specificity for luminal B-type breast cancer.
Filippa Pettersson, Christina Yau, +11 authors, Wilson H Miller.
Clin Cancer Res, 2011 Mar 19; 17(9). PMID: 21415224    Free PMC article.
Microarray-based class discovery for molecular classification of breast cancer: analysis of interobserver agreement.
Alan Mackay, Britta Weigelt, +7 authors, Jorge S Reis-Filho.
J Natl Cancer Inst, 2011 Mar 23; 103(8). PMID: 21421860    Free PMC article.
Assessment of Topoisomerase II α status in breast cancer by quantitative PCR, gene expression microarrays, immunohistochemistry, and fluorescence in situ hybridization.
Atocha Romero, Miguel Martín, +9 authors, Trinidad Caldés Llopis.
Am J Pathol, 2011 Mar 26; 178(4). PMID: 21435434    Free PMC article.
Review.
GOBO: gene expression-based outcome for breast cancer online.
Markus Ringnér, Erik Fredlund, +2 authors, Johan Staaf.
PLoS One, 2011 Mar 30; 6(3). PMID: 21445301    Free PMC article.
Highly Cited.
Breast cancer proteomics: a review for clinicians.
E R C G N Galvão, L M S Martins, +2 authors, S J H Monte.
J Cancer Res Clin Oncol, 2011 Apr 06; 137(6). PMID: 21465318
Review.
Topology based data analysis identifies a subgroup of breast cancers with a unique mutational profile and excellent survival.
Monica Nicolau, Arnold J Levine, Gunnar Carlsson.
Proc Natl Acad Sci U S A, 2011 Apr 13; 108(17). PMID: 21482760    Free PMC article.
Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization.
Kuo-Jang Kao, Kai-Ming Chang, Hui-Chi Hsu, Andrew T Huang.
BMC Cancer, 2011 Apr 20; 11. PMID: 21501481    Free PMC article.
Highly Cited.
Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications.
Taru A Muranen, Dario Greco, +7 authors, Heli Nevanlinna.
Breast Cancer Res, 2011 May 06; 13(5). PMID: 21542898    Free PMC article.
Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based intrinsic subtype--ACOSOG Z1031.
Matthew J Ellis, Vera J Suman, +17 authors, John A Olson.
J Clin Oncol, 2011 May 11; 29(17). PMID: 21555689    Free PMC article.
Highly Cited.
Preoperative chemotherapy for operable breast cancer improves surgical outcomes in the community hospital setting.
Ian K Komenaka, Michael L Hibbard, +4 authors, Chandra Jha.
Oncologist, 2011 May 12; 16(6). PMID: 21558133    Free PMC article.
A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.
Christos Hatzis, Lajos Pusztai, +27 authors, W Fraser Symmans.
JAMA, 2011 May 12; 305(18). PMID: 21558518    Free PMC article.
Highly Cited.
Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse.
J Chuck Harrell, Aleix Prat, +6 authors, Charles M Perou.
Breast Cancer Res Treat, 2011 Jun 15; 132(2). PMID: 21671017    Free PMC article.
Highly Cited.
Strategies for subtypes--dealing with the diversity of breast cancer: highlights of the St. Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011.
A Goldhirsch, W C Wood, +4 authors, Panel members.
Ann Oncol, 2011 Jun 29; 22(8). PMID: 21709140    Free PMC article.
Highly Cited.
FGFR signaling promotes the growth of triple-negative and basal-like breast cancer cell lines both in vitro and in vivo.
Rachel Sharpe, Alex Pearson, +8 authors, Nicholas C Turner.
Clin Cancer Res, 2011 Jun 30; 17(16). PMID: 21712446    Free PMC article.
Systematic bias in genomic classification due to contaminating non-neoplastic tissue in breast tumor samples.
Fathi Elloumi, Zhiyuan Hu, +4 authors, Melissa A Troester.
BMC Med Genomics, 2011 Jul 02; 4. PMID: 21718502    Free PMC article.
Targeting androgen receptor in estrogen receptor-negative breast cancer.
Min Ni, Yiwen Chen, +6 authors, Myles Brown.
Cancer Cell, 2011 Jul 12; 20(1). PMID: 21741601    Free PMC article.
Highly Cited.
An evaluation protocol for subtype-specific breast cancer event prediction.
Herman M J Sontrop, Wim F J Verhaegh, Marcel J T Reinders, Perry D Moerland.
PLoS One, 2011 Jul 16; 6(7). PMID: 21760900    Free PMC article.
Nottingham Prognostic Index in triple-negative breast cancer: a reliable prognostic tool?
André Albergaria, Sara Ricardo, +5 authors, Fernando Schmitt.
BMC Cancer, 2011 Jul 19; 11. PMID: 21762477    Free PMC article.
A pharmacogenomic method for individualized prediction of drug sensitivity.
Adam L Cohen, Raffaella Soldi, +8 authors, Andrea H Bild.
Mol Syst Biol, 2011 Jul 21; 7. PMID: 21772261    Free PMC article.
A refined molecular taxonomy of breast cancer.
M Guedj, L Marisa, +19 authors, C Theillet.
Oncogene, 2011 Jul 26; 31(9). PMID: 21785460    Free PMC article.
Highly Cited.
Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction.
Pierre-Emmanuel Colombo, Fernanda Milanezi, Britta Weigelt, Jorge S Reis-Filho.
Breast Cancer Res, 2011 Jul 27; 13(3). PMID: 21787441    Free PMC article.
Review.
Nab-paclitaxel for the treatment of breast cancer: efficacy, safety, and approval.
Yutaka Yamamoto, Ichiro Kawano, Hirotaka Iwase.
Onco Targets Ther, 2011 Jul 28; 4. PMID: 21792318    Free PMC article.
Selective genomic copy number imbalances and probability of recurrence in early-stage breast cancer.
Patricia A Thompson, Abenaa M Brewster, +12 authors, Melissa L Bondy.
PLoS One, 2011 Aug 23; 6(8). PMID: 21858162    Free PMC article.
An iron regulatory gene signature predicts outcome in breast cancer.
Lance D Miller, Lan G Coffman, +5 authors, Frank M Torti.
Cancer Res, 2011 Aug 31; 71(21). PMID: 21875943    Free PMC article.
Challenges translating breast cancer gene signatures into the clinic.
Britta Weigelt, Lajos Pusztai, Alan Ashworth, Jorge S Reis-Filho.
Nat Rev Clin Oncol, 2011 Sep 01; 9(1). PMID: 21878891
Review.
Relationship between quantitative GRB7 RNA expression and recurrence after adjuvant anthracycline chemotherapy in triple-negative breast cancer.
Joseph A Sparano, Lori J Goldstein, +13 authors, Robert Gray.
Clin Cancer Res, 2011 Sep 22; 17(22). PMID: 21933890    Free PMC article.
A new gene expression signature, the ClinicoMolecular Triad Classification, may improve prediction and prognostication of breast cancer at the time of diagnosis.
Dong-Yu Wang, Susan J Done, +3 authors, Wey Liang Leong.
Breast Cancer Res, 2011 Sep 24; 13(5). PMID: 21939527    Free PMC article.
Breast cancer - one term, many entities?
Nicholas R Bertos, Morag Park.
J Clin Invest, 2011 Oct 04; 121(10). PMID: 21965335    Free PMC article.
Highly Cited. Review.
Insight into the heterogeneity of breast cancer through next-generation sequencing.
Hege G Russnes, Nicholas Navin, James Hicks, Anne-Lise Borresen-Dale.
J Clin Invest, 2011 Oct 04; 121(10). PMID: 21965338    Free PMC article.
Highly Cited. Review.
The Promise and the Problems of Epigenetics Biomarkers in Cancer.
Attila T Lorincz.
Expert Opin Med Diagn, 2011 Oct 18; 5(5). PMID: 22003365    Free PMC article.
Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes.
Yoko S DeRose, Guoying Wang, +12 authors, Alana L Welm.
Nat Med, 2011 Oct 25; 17(11). PMID: 22019887    Free PMC article.
Highly Cited.
Quality assurance of RNA expression profiling in clinical laboratories.
Weihua Tang, Zhiyuan Hu, Hind Muallem, Margaret L Gulley.
J Mol Diagn, 2011 Oct 25; 14(1). PMID: 22020152    Free PMC article.
Review.
Integrating contextual miRNA and protein signatures for diagnostic and treatment decisions in cancer.
Lorenzo F Sempere.
Expert Rev Mol Diagn, 2011 Oct 26; 11(8). PMID: 22022944    Free PMC article.
Review.
Effects of tissue handling on RNA integrity and microarray measurements from resected breast cancers.
Christos Hatzis, Hongxia Sun, +6 authors, W Fraser Symmans.
J Natl Cancer Inst, 2011 Oct 29; 103(24). PMID: 22034635    Free PMC article.
Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features.
Vilde D Haakensen, Ole Christian Lingjaerde, +14 authors, Aslaug Helland.
BMC Med Genomics, 2011 Nov 03; 4. PMID: 22044755    Free PMC article.
Altered expression of insulin receptor isoforms in breast cancer.
Jiaqi Huang, Chris Morehouse, +12 authors, Yihong Yao.
PLoS One, 2011 Nov 03; 6(10). PMID: 22046260    Free PMC article.
Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival.
Victor J Weigman, Hann-Hsiang Chao, +11 authors, Charles M Perou.
Breast Cancer Res Treat, 2011 Nov 04; 133(3). PMID: 22048815    Free PMC article.
Molecular characterisation of formalin-fixed paraffin-embedded (FFPE) breast tumour specimens using a custom 512-gene breast cancer bead array-based platform.
M Abramovitz, B G Barwick, +8 authors, B Leyland-Jones.
Br J Cancer, 2011 Nov 10; 105(10). PMID: 22067903    Free PMC article.
Basal breast cancer: a complex and deadly molecular subtype.
F Bertucci, P Finetti, D Birnbaum.
Curr Mol Med, 2011 Nov 16; 12(1). PMID: 22082486    Free PMC article.
Review.
RNA helicase DDX5 regulates microRNA expression and contributes to cytoskeletal reorganization in basal breast cancer cells.
Daojing Wang, Jing Huang, Zhi Hu.
Mol Cell Proteomics, 2011 Nov 17; 11(2). PMID: 22086602    Free PMC article.
The colony-stimulating factor-1 (CSF-1) receptor sustains ERK1/2 activation and proliferation in breast cancer cell lines.
Andrea Morandi, Valentina Barbetti, +2 authors, Elisabetta Rovida.
PLoS One, 2011 Nov 19; 6(11). PMID: 22096574    Free PMC article.
The breast cancer genome--a key for better oncology.
Hans Kristian Moen Vollan, Carlos Caldas.
BMC Cancer, 2011 Dec 02; 11. PMID: 22128823    Free PMC article.
Review.
Invasive Breast Cancer: Recognition of Molecular Subtypes.
Johanna D Strehl, David L Wachter, +2 authors, Arndt Hartmann.
Breast Care (Basel), 2011 Dec 03; 6(4). PMID: 22135623    Free PMC article.
Triple-Negative Breast Cancer: Clinical and Histological Correlations.
Zeinab Elsawaf, Hans-Peter Sinn.
Breast Care (Basel), 2011 Dec 03; 6(4). PMID: 22135625    Free PMC article.
TRIM29 functions as a tumor suppressor in nontumorigenic breast cells and invasive ER+ breast cancer.
Jin Liu, Bryan Welm, +2 authors, Philip S Bernard.
Am J Pathol, 2011 Dec 06; 180(2). PMID: 22138580    Free PMC article.
Practical implications of gene-expression-based assays for breast oncologists.
Aleix Prat, Matthew J Ellis, Charles M Perou.
Nat Rev Clin Oncol, 2011 Dec 07; 9(1). PMID: 22143140    Free PMC article.
Highly Cited. Review.
Triple-negative subtype predicts poor overall survival and high locoregional relapse in inflammatory breast cancer.
Jing Li, Ana M Gonzalez-Angulo, +12 authors, Thomas A Buchholz.
Oncologist, 2011 Dec 08; 16(12). PMID: 22147002    Free PMC article.
Opposing effects of Runx2 and estradiol on breast cancer cell proliferation: in vitro identification of reciprocally regulated gene signature related to clinical letrozole responsiveness.
Nyam-Osor Chimge, Sanjeev K Baniwal, +6 authors, Baruch Frenkel.
Clin Cancer Res, 2011 Dec 08; 18(3). PMID: 22147940    Free PMC article.
Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer.
Gary C Hon, R David Hawkins, +14 authors, Bing Ren.
Genome Res, 2011 Dec 14; 22(2). PMID: 22156296    Free PMC article.
Highly Cited.
Landscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer.
Johan Staaf, Göran Jönsson, +2 authors, Ake Borg.
Breast Cancer Res, 2011 Dec 16; 13(6). PMID: 22169037    Free PMC article.
Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer.
Yun-Yong Park, Kyounghyun Kim, +11 authors, Ju-Seog Lee.
EMBO Mol Med, 2011 Dec 17; 4(1). PMID: 22174013    Free PMC article.
Characterization of uncertainty in the classification of multivariate assays: application to PAM50 centroid-based genomic predictors for breast cancer treatment plans.
Mark Tw Ebbert, Roy Rl Bastien, +6 authors, Julio C Facelli.
J Clin Bioinforma, 2011 Dec 27; 1. PMID: 22196354    Free PMC article.
Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).
Laura J Esserman, Donald A Berry, +32 authors, I-SPY 1 TRIAL Investigators.
Breast Cancer Res Treat, 2011 Dec 27; 132(3). PMID: 22198468    Free PMC article.
Highly Cited.
'Omic approaches to preventing or managing metastatic breast cancer.
Obi L Griffith, Joe W Gray.
Breast Cancer Res, 2012 Jan 06; 13(6). PMID: 22216753    Free PMC article.
Review.
Luminal-B breast cancer and novel therapeutic targets.
Ben Tran, Philippe L Bedard.
Breast Cancer Res, 2012 Jan 06; 13(6). PMID: 22217398    Free PMC article.
Review.
Gene expression, molecular class changes, and pathway analysis after neoadjuvant systemic therapy for breast cancer.
Ana M Gonzalez-Angulo, Takayuki Iwamoto, +7 authors, Lajos Pusztai.
Clin Cancer Res, 2012 Jan 12; 18(4). PMID: 22235097    Free PMC article.
Race and hormone receptor-positive breast cancer outcomes in a randomized chemotherapy trial.
Joseph A Sparano, Molin Wang, +9 authors, Nancy E Davidson.
J Natl Cancer Inst, 2012 Jan 18; 104(5). PMID: 22250182    Free PMC article.
A three-gene model to robustly identify breast cancer molecular subtypes.
Benjamin Haibe-Kains, Christine Desmedt, +4 authors, Christos Sotiriou.
J Natl Cancer Inst, 2012 Jan 21; 104(4). PMID: 22262870    Free PMC article.
Highly Cited.
Gene expression profiling: changing face of breast cancer classification and management.
Robert Wesolowski, Bhuvaneswari Ramaswamy.
Gene Expr, 2012 Jan 25; 15(3). PMID: 22268293    Free PMC article.
Review.
Molecular basis of triple negative breast cancer and implications for therapy.
Parvin F Peddi, Matthew J Ellis, Cynthia Ma.
Int J Breast Cancer, 2012 Feb 02; 2012. PMID: 22295242    Free PMC article.
Minireview: Inflammation: an instigator of more aggressive estrogen receptor (ER) positive breast cancers.
Sarah C Baumgarten, Jonna Frasor.
Mol Endocrinol, 2012 Feb 04; 26(3). PMID: 22301780    Free PMC article.
Review.
Targeting of primary breast cancers and metastases in a transgenic mouse model using rationally designed multifunctional SPIONs.
Forrest M Kievit, Zachary R Stephen, +7 authors, Miqin Zhang.
ACS Nano, 2012 Feb 14; 6(3). PMID: 22324543    Free PMC article.
Responsiveness of intrinsic subtypes to adjuvant anthracycline substitution in the NCIC.CTG MA.5 randomized trial.
Maggie C U Cheang, K David Voduc, +15 authors, Torsten O Nielsen.
Clin Cancer Res, 2012 Feb 22; 18(8). PMID: 22351696    Free PMC article.
Expression profiling of cancerous and normal breast tissues identifies microRNAs that are differentially expressed in serum from patients with (metastatic) breast cancer and healthy volunteers.
Eleni van Schooneveld, Maartje Ca Wouters, +7 authors, Steven J Van Laere.
Breast Cancer Res, 2012 Feb 23; 14(1). PMID: 22353773    Free PMC article.
Highly Cited.
A gene signature for predicting outcome in patients with basal-like breast cancer.
Robin M Hallett, Anna Dvorkin-Gheva, Anita Bane, John A Hassell.
Sci Rep, 2012 Feb 23; 2. PMID: 22355741    Free PMC article.
Transcriptomic landscape of breast cancers through mRNA sequencing.
Jeyanthy Eswaran, Dinesh Cyanam, +7 authors, Rakesh Kumar.
Sci Rep, 2012 Feb 23; 2. PMID: 22355776    Free PMC article.
A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers.
Rachael Natrajan, Alan Mackay, +30 authors, Jorge S Reis-Filho.
J Pathol, 2012 Mar 01; 227(1). PMID: 22362584    Free PMC article.
Topoisomerase 2 alpha: a real predictor of anthracycline efficacy?
Atocha Romero, Trinidad Caldés, Eduardo Díaz-Rubio, Miguel Martín.
Clin Transl Oncol, 2012 Mar 01; 14(3). PMID: 22374418
Review.
Correlations between diffusion-weighted imaging and breast cancer biomarkers.
Laura Martincich, Veronica Deantoni, +9 authors, Filippo Montemurro.
Eur Radiol, 2012 Mar 14; 22(7). PMID: 22411304
Agreement in risk prediction between the 21-gene recurrence score assay (Oncotype DX®) and the PAM50 breast cancer intrinsic Classifier™ in early-stage estrogen receptor-positive breast cancer.
Catherine M Kelly, Philip S Bernard, +7 authors, Lajos Pusztai.
Oncologist, 2012 Mar 16; 17(4). PMID: 22418568    Free PMC article.
Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models.
Cynthia X Ma, Shirong Cai, +10 authors, Helen Piwnica-Worms.
J Clin Invest, 2012 Mar 27; 122(4). PMID: 22446188    Free PMC article.
Highly Cited.
The clonal and mutational evolution spectrum of primary triple-negative breast cancers.
Sohrab P Shah, Andrew Roth, +56 authors, Samuel Aparicio.
Nature, 2012 Apr 13; 486(7403). PMID: 22495314    Free PMC article.
Highly Cited.
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.
Christina Curtis, Sohrab P Shah, +29 authors, Samuel Aparicio.
Nature, 2012 Apr 24; 486(7403). PMID: 22522925    Free PMC article.
Highly Cited.
Concordance among gene expression-based predictors for ER-positive breast cancer treated with adjuvant tamoxifen.
A Prat, J S Parker, +9 authors, C M Perou.
Ann Oncol, 2012 Apr 26; 23(11). PMID: 22532584    Free PMC article.
Basal-like breast cancer cells induce phenotypic and genomic changes in macrophages.
Delisha A Stewart, Yinmeng Yang, Liza Makowski, Melissa A Troester.
Mol Cancer Res, 2012 Apr 26; 10(6). PMID: 22532586    Free PMC article.
Crk adaptor proteins act as key signaling integrators for breast tumorigenesis.
Kelly E Fathers, Emily S Bell, +12 authors, Morag Park.
Breast Cancer Res, 2012 May 10; 14(3). PMID: 22569336    Free PMC article.
Loss of cell-surface laminin anchoring promotes tumor growth and is associated with poor clinical outcomes.
Armin Akhavan, Obi L Griffith, +5 authors, John L Muschler.
Cancer Res, 2012 May 17; 72(10). PMID: 22589276    Free PMC article.
Exploring molecular pathways of triple-negative breast cancer.
Valeria Ossovskaya, Yipeng Wang, +6 authors, Nikolai Daraselia.
Genes Cancer, 2012 May 18; 2(9). PMID: 22593799    Free PMC article.
Quantitative in situ measurement of estrogen receptor mRNA predicts response to tamoxifen.
Jennifer M Bordeaux, Huan Cheng, +7 authors, David L Rimm.
PLoS One, 2012 May 19; 7(5). PMID: 22606272    Free PMC article.
Splitting random forest (SRF) for determining compact sets of genes that distinguish between cancer subtypes.
Xiaowei Guan, Mark R Chance, Jill S Barnholtz-Sloan.
J Clin Bioinforma, 2012 May 24; 2(1). PMID: 22616791    Free PMC article.
Overrepresentation of transcription factor families in the genesets underlying breast cancer subtypes.
Himanshu Joshi, Silje H Nord, +2 authors, Vessela N Kristensen.
BMC Genomics, 2012 May 24; 13. PMID: 22616941    Free PMC article.
JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer.
Yi Fang Lee, Lance David Miller, +6 authors, Kartiki V Desai.
Breast Cancer Res, 2012 May 25; 14(3). PMID: 22621393    Free PMC article.
The implications of breast cancer molecular phenotype for radiation oncology.
Shirin Sioshansi, Kathryn E Huber, David E Wazer.
Front Oncol, 2011 Jan 01; 1. PMID: 22649753    Free PMC article.
TBCRC 001: randomized phase II study of cetuximab in combination with carboplatin in stage IV triple-negative breast cancer.
Lisa A Carey, Hope S Rugo, +17 authors, Eric P Winer.
J Clin Oncol, 2012 Jun 06; 30(21). PMID: 22665533    Free PMC article.
Highly Cited.
Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance.
Justin M Balko, Rebecca S Cook, +15 authors, Carlos L Arteaga.
Nat Med, 2012 Jun 12; 18(7). PMID: 22683778    Free PMC article.
Highly Cited.
Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression.
Todd P Knutson, Andrea R Daniel, +4 authors, Carol A Lange.
Breast Cancer Res, 2012 Jun 16; 14(3). PMID: 22697792    Free PMC article.
A 50-gene intrinsic subtype classifier for prognosis and prediction of benefit from adjuvant tamoxifen.
Stephen K Chia, Vivien H Bramwell, +12 authors, Torsten O Nielsen.
Clin Cancer Res, 2012 Jun 20; 18(16). PMID: 22711706    Free PMC article.
Highly Cited.
PAM50 assay and the three-gene model for identifying the major and clinically relevant molecular subtypes of breast cancer.
A Prat, J S Parker, C Fan, C M Perou.
Breast Cancer Res Treat, 2012 Jul 04; 135(1). PMID: 22752290    Free PMC article.
Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.
Karolina Holm, Dorthe Grabau, +13 authors, Markus Ringnér.
Mol Oncol, 2012 Jul 07; 6(5). PMID: 22766277    Free PMC article.
High-risk estrogen-receptor-positive breast cancer: identification and implications for therapy.
Rosemary L Balleine, Nicholas R Wilcken.
Mol Diagn Ther, 2012 Jul 21; 16(4). PMID: 22812573
Review.
Distinct genes related to drug response identified in ER positive and ER negative breast cancer cell lines.
Kui Shen, Shara D Rice, +9 authors, Nan Song.
PLoS One, 2012 Jul 21; 7(7). PMID: 22815861    Free PMC article.
Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures.
Peter Kabos, Jessica Finlay-Schultz, +8 authors, Carol A Sartorius.
Breast Cancer Res Treat, 2012 Jul 24; 135(2). PMID: 22821401    Free PMC article.
The gene expression landscape of breast cancer is shaped by tumor protein p53 status and epithelial-mesenchymal transition.
Erik Fredlund, Johan Staaf, +3 authors, Markus Ringnér.
Breast Cancer Res, 2012 Jul 31; 14(4). PMID: 22839103    Free PMC article.
An "elite hacker": breast tumors exploit the normal microenvironment program to instruct their progression and biological diversity.
Aaron Boudreau, Laura J van't Veer, Mina J Bissell.
Cell Adh Migr, 2012 Aug 07; 6(3). PMID: 22863741    Free PMC article.
Review.
Association of primary tumour FDG uptake with clinical, histopathological and molecular characteristics in breast cancer patients scheduled for neoadjuvant chemotherapy.
B B Koolen, M J T F D Vrancken Peeters, +8 authors, R A Valdés Olmos.
Eur J Nucl Med Mol Imaging, 2012 Aug 17; 39(12). PMID: 22895862
Direct integration of intensity-level data from Affymetrix and Illumina microarrays improves statistical power for robust reanalysis.
Arran K Turnbull, Robert R Kitchen, +3 authors, Andrew H Sims.
BMC Med Genomics, 2012 Aug 23; 5. PMID: 22909195    Free PMC article.
PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA-proficient triple-negative breast cancer to PARP inhibition.
Yasir H Ibrahim, Celina García-García, +18 authors, José Baselga.
Cancer Discov, 2012 Aug 24; 2(11). PMID: 22915752    Free PMC article.
Highly Cited.
Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors.
Laura A Petrillo, Denise M Wolf, +12 authors, Laura J Esserman.
Breast Cancer Res Treat, 2012 Sep 04; 135(3). PMID: 22941572    Free PMC article.
The molecular profile of luminal B breast cancer.
Chad J Creighton.
Biologics, 2012 Sep 08; 6. PMID: 22956860    Free PMC article.
Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer.
Esther H Lips, Rita A Mukhtar, +13 authors, I-SPY TRIAL Investigators.
Breast Cancer Res Treat, 2012 Sep 11; 136(1). PMID: 22961065    Free PMC article.
The interaction between ER and NFκB in resistance to endocrine therapy.
Leen Sas, Filip Lardon, +5 authors, Steven J Van Laere.
Breast Cancer Res, 2012 Sep 12; 14(4). PMID: 22963717    Free PMC article.
Review.
Preoperative FDG PET/CT in breast cancer patients: where are we going?
Laura Gilardi, Concetta De Cicco, Giovanni Paganelli.
Eur J Nucl Med Mol Imaging, 2012 Sep 15; 39(11). PMID: 22976500
A pathway-based classification of breast cancer integrating data on differentially expressed genes, copy number variations and microRNA target genes.
Hae-Seok Eo, Jee Yeon Heo, +2 authors, Hyung-Seok Choi.
Mol Cells, 2012 Sep 18; 34(4). PMID: 22983731    Free PMC article.
FH535 inhibited migration and growth of breast cancer cells.
Joji Iida, Jesse Dorchak, +8 authors, Craig D Shriver.
PLoS One, 2012 Sep 18; 7(9). PMID: 22984505    Free PMC article.
Comprehensive molecular portraits of human breast tumours.
Cancer Genome Atlas Network.
Nature, 2012 Sep 25; 490(7418). PMID: 23000897    Free PMC article.
Highly Cited.
Radiation therapy following surgery for localized breast cancer: outcome prediction by classical prognostic factors and approximated genetic subtypes.
Roberto Pacelli, Manuel Conson, +8 authors, Marco Salvatore.
J Radiat Res, 2012 Sep 29; 54(2). PMID: 23019151    Free PMC article.
Human epidermal growth factor receptor-2-positive breast cancer: does estrogen receptor status define two distinct subtypes?
I Vaz-Luis, E P Winer, N U Lin.
Ann Oncol, 2012 Oct 02; 24(2). PMID: 23022997    Free PMC article.
Review.
EndoPredict improves the prognostic classification derived from common clinical guidelines in ER-positive, HER2-negative early breast cancer.
P Dubsky, M Filipits, +17 authors, Austrian Breast and Colorectal Cancer Study Group (ABCSG).
Ann Oncol, 2012 Oct 05; 24(3). PMID: 23035151    Free PMC article.
PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers.
Roy R L Bastien, Álvaro Rodríguez-Lescure, +29 authors, Miguel Martín.
BMC Med Genomics, 2012 Oct 06; 5. PMID: 23035882    Free PMC article.
Highly Cited.
Decentral gene expression analysis: analytical validation of the Endopredict genomic multianalyte breast cancer prognosis test.
Ralf Kronenwett, Kerstin Bohmann, +16 authors, Carsten Denkert.
BMC Cancer, 2012 Oct 09; 12. PMID: 23039280    Free PMC article.
The RUNX family in breast cancer: relationships with estrogen signaling.
N-O Chimge, B Frenkel.
Oncogene, 2012 Oct 10; 32(17). PMID: 23045283    Free PMC article.
Review.
Prediction consistency and clinical presentations of breast cancer molecular subtypes for Han Chinese population.
Chi-Cheng Huang, Shih-Hsin Tu, +7 authors, Eric Y Chuang.
J Transl Med, 2012 Oct 25; 10 Suppl 1. PMID: 23046482    Free PMC article.
Co-expression of HER2 and HER3 receptor tyrosine kinases enhances invasion of breast cells via stimulation of interleukin-8 autocrine secretion.
Nicola Aceto, Stephan Duss, +4 authors, Mohamed Bentires-Alj.
Breast Cancer Res, 2012 Oct 16; 14(5). PMID: 23062209    Free PMC article.
Comparative effectiveness research, genomics-enabled personalized medicine, and rapid learning health care: a common bond.
Geoffrey S Ginsburg, Nicole M Kuderer.
J Clin Oncol, 2012 Oct 17; 30(34). PMID: 23071236    Free PMC article.
Review.
Update on triple-negative breast cancer: prognosis and management strategies.
Olivier Brouckaert, Hans Wildiers, Giuseppe Floris, Patrick Neven.
Int J Womens Health, 2012 Oct 17; 4. PMID: 23071421    Free PMC article.
Potential tumorigenic programs associated with TP53 mutation status reveal role of VEGF pathway.
H Joshi, G Bhanot, A-L Børresen-Dale, V Kristensen.
Br J Cancer, 2012 Oct 20; 107(10). PMID: 23079576    Free PMC article.
Regulation of mRNA expression in breast cancer - a cis-tematic trans-action.
Roel G W Verhaak, Gordon B Mills.
Breast Cancer Res, 2012 Oct 31; 14(5). PMID: 23106814    Free PMC article.
Py2T murine breast cancer cells, a versatile model of TGFβ-induced EMT in vitro and in vivo.
Lorenz Waldmeier, Nathalie Meyer-Schaller, Maren Diepenbruck, Gerhard Christofori.
PLoS One, 2012 Nov 13; 7(11). PMID: 23144919    Free PMC article.
Molecular characterisation of cell line models for triple-negative breast cancers.
Anita Grigoriadis, Alan Mackay, +5 authors, Andrew Tutt.
BMC Genomics, 2012 Nov 16; 13. PMID: 23151021    Free PMC article.
Clinical implementation of RNA signatures for pharmacogenomic decision-making.
Weihua Tang, Zhiyuan Hu, Hind Muallem, Margaret L Gulley.
Pharmgenomics Pers Med, 2011 Jan 01; 4. PMID: 23226056    Free PMC article.
Prognostic significance of progesterone receptor-positive tumor cells within immunohistochemically defined luminal A breast cancer.
Aleix Prat, Maggie Chon U Cheang, +8 authors, Charles M Perou.
J Clin Oncol, 2012 Dec 13; 31(2). PMID: 23233704    Free PMC article.
Highly Cited.
Vimentin DNA methylation predicts survival in breast cancer.
Jacob Ulirsch, Cheng Fan, +4 authors, Theresa Swift-Scanlan.
Breast Cancer Res Treat, 2012 Dec 15; 137(2). PMID: 23239149    Free PMC article.
A phase II study of UCN-01 in combination with irinotecan in patients with metastatic triple negative breast cancer.
Cynthia X Ma, Matthew J C Ellis, +19 authors, Paula M Fracasso.
Breast Cancer Res Treat, 2012 Dec 18; 137(2). PMID: 23242585    Free PMC article.
Prognostically relevant gene signatures of high-grade serous ovarian carcinoma.
Roel G W Verhaak, Pablo Tamayo, +39 authors, Cancer Genome Atlas Research Network.
J Clin Invest, 2012 Dec 22; 123(1). PMID: 23257362    Free PMC article.
Highly Cited.
Micro-scale genomic DNA copy number aberrations as another means of mutagenesis in breast cancer.
Hann-Hsiang Chao, Xiaping He, +2 authors, Charles M Perou.
PLoS One, 2013 Jan 04; 7(12). PMID: 23284754    Free PMC article.
The genomic landscape of breast cancer as a therapeutic roadmap.
Matthew J Ellis, Charles M Perou.
Cancer Discov, 2013 Jan 16; 3(1). PMID: 23319768    Free PMC article.
Highly Cited.
Transcriptional shift identifies a set of genes driving breast cancer chemoresistance.
Laura Vera-Ramirez, Pedro Sanchez-Rovira, +3 authors, Jose A Lorente.
PLoS One, 2013 Jan 18; 8(1). PMID: 23326553    Free PMC article.
Mask is required for the activity of the Hippo pathway effector Yki/YAP.
Leticia Sansores-Garcia, Mardelle Atkins, +4 authors, Georg Halder.
Curr Biol, 2013 Jan 22; 23(3). PMID: 23333314    Free PMC article.
Utility of prognostic genomic tests in breast cancer practice: The IMPAKT 2012 Working Group Consensus Statement.
H A Azim, S Michiels, +9 authors, C Swanton.
Ann Oncol, 2013 Jan 23; 24(3). PMID: 23337633    Free PMC article.
Murine microenvironment metaprofiles associate with human cancer etiology and intrinsic subtypes.
David H Nguyen, Erik Fredlund, +4 authors, Mary Helen Barcellos-Hoff.
Clin Cancer Res, 2013 Jan 23; 19(6). PMID: 23339125    Free PMC article.
Patient-derived breast tumor xenografts facilitating personalized cancer therapy.
Melissa D Landis, Brian D Lehmann, Jennifer A Pietenpol, Jenny C Chang.
Breast Cancer Res, 2013 Jan 24; 15(1). PMID: 23339383    Free PMC article.
Review.
MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11.
Jessica Bockhorn, Rachel Dalton, +16 authors, Huiping Liu.
Nat Commun, 2013 Jan 24; 4. PMID: 23340433    Free PMC article.
Highly Cited.
Visualizing multidimensional cancer genomics data.
Michael P Schroeder, Abel Gonzalez-Perez, Nuria Lopez-Bigas.
Genome Med, 2013 Feb 01; 5(1). PMID: 23363777    Free PMC article.
Review.
Translating metastasis-related biomarkers to the clinic--progress and pitfalls.
François-Clément Bidard, Jean-Yves Pierga, Jean-Charles Soria, Jean Paul Thiery.
Nat Rev Clin Oncol, 2013 Feb 06; 10(3). PMID: 23381003
Review.
A data similarity-based strategy for meta-analysis of transcriptional profiles in cancer.
Qingchao Qiu, Pengcheng Lu, +6 authors, Yajun Yi.
PLoS One, 2013 Feb 06; 8(1). PMID: 23383020    Free PMC article.
A new genome-driven integrated classification of breast cancer and its implications.
Sarah-Jane Dawson, Oscar M Rueda, Samuel Aparicio, Carlos Caldas.
EMBO J, 2013 Feb 12; 32(5). PMID: 23395906    Free PMC article.
Highly Cited. Review.
Uncovering the molecular secrets of inflammatory breast cancer biology: an integrated analysis of three distinct affymetrix gene expression datasets.
Steven J Van Laere, Naoto T Ueno, +15 authors, François Bertucci.
Clin Cancer Res, 2013 Feb 12; 19(17). PMID: 23396049    Free PMC article.
Molecular characterization of basal-like and non-basal-like triple-negative breast cancer.
Aleix Prat, Barbara Adamo, +3 authors, Charles M Perou.
Oncologist, 2013 Feb 14; 18(2). PMID: 23404817    Free PMC article.
Highly Cited. Review.
PAM50 proliferation score as a predictor of weekly paclitaxel benefit in breast cancer.
Miguel Martín, Aleix Prat, +24 authors, Philip S Bernard.
Breast Cancer Res Treat, 2013 Feb 21; 138(2). PMID: 23423445    Free PMC article.
Comprehensive analysis of BRCA1, BRCA2 and TP53 germline mutation and tumor characterization: a portrait of early-onset breast cancer in Brazil.
Dirce Maria Carraro, Maria Aparecida Azevedo Koike Folgueira, +14 authors, Maria Mitzi Brentani.
PLoS One, 2013 Mar 08; 8(3). PMID: 23469205    Free PMC article.
Protein kinase Cδ is required for ErbB2-driven mammary gland tumorigenesis and negatively correlates with prognosis in human breast cancer.
B L Allen-Petersen, C J Carter, A M Ohm, M E Reyland.
Oncogene, 2013 Mar 12; 33(10). PMID: 23474764    Free PMC article.
Targeting the PyMT Oncogene to Diverse Mammary Cell Populations Enhances Tumor Heterogeneity and Generates Rare Breast Cancer Subtypes.
Brittni A Smith, Dawne N Shelton, +5 authors, Bryan E Welm.
Genes Cancer, 2013 Mar 15; 3(9-10). PMID: 23486760    Free PMC article.
Embryonic mammary signature subsets are activated in Brca1-/- and basal-like breast cancers.
Marketa Zvelebil, Erik Oliemuller, +6 authors, Beatrice A Howard.
Breast Cancer Res, 2013 Mar 20; 15(2). PMID: 23506684    Free PMC article.
Classification of time series gene expression in clinical studies via integration of biological network.
Liwei Qian, Haoran Zheng, +2 authors, Jinlong Li.
PLoS One, 2013 Mar 22; 8(3). PMID: 23516469    Free PMC article.
Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways.
Margit L H Riis, Xi Zhao, +6 authors, Vessela N Kristensen.
ISRN Oncol, 2013 Mar 28; 2013. PMID: 23533813    Free PMC article.
Identification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer.
Ke-Da Yu, Rui Zhu, +11 authors, Jenny C Chang.
Clin Cancer Res, 2013 Apr 04; 19(10). PMID: 23549873    Free PMC article.
High expression of KIF26B in breast cancer associates with poor prognosis.
Qun Wang, Zong-Bin Zhao, +4 authors, Hong Zheng.
PLoS One, 2013 Apr 16; 8(4). PMID: 23585914    Free PMC article.
Usefulness of pretreatment neutrophil to lymphocyte ratio in predicting disease-specific survival in breast cancer patients.
Hany Noh, Minseob Eomm, Airi Han.
J Breast Cancer, 2013 Apr 18; 16(1). PMID: 23593082    Free PMC article.
Highly Cited.
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer.
Adam A Margolin, Erhan Bilal, +27 authors, Anne-Lise Børresen-Dale.
Sci Transl Med, 2013 Apr 19; 5(181). PMID: 23596205    Free PMC article.
A comprehensive analysis of Aurora A; transcript levels are the most reliable in association with proliferation and prognosis in breast cancer.
Satoko Yamamoto, Mutsuko Yamamoto-Ibusuki, +2 authors, Hirotaka Iwase.
BMC Cancer, 2013 May 01; 13. PMID: 23627634    Free PMC article.
Molecular subtypes of breast cancer: metabolic correlation with ¹⁸F-FDG PET/CT.
Ana María García Vicente, Ángel Soriano Castrejón, +6 authors, Ana González Ageitos.
Eur J Nucl Med Mol Imaging, 2013 May 02; 40(9). PMID: 23632960
Association between SPARC mRNA expression, prognosis and response to neoadjuvant chemotherapy in early breast cancer: a pooled in-silico analysis.
Hatem A Azim, Sandeep Singhal, +7 authors, Christos Sotiriou.
PLoS One, 2013 May 03; 8(4). PMID: 23638089    Free PMC article.
Multiple suboptimal solutions for prediction rules in gene expression data.
Osamu Komori, Mari Pritchard, Shinto Eguchi.
Comput Math Methods Med, 2013 May 11; 2013. PMID: 23662163    Free PMC article.
Expression of VEGF and semaphorin genes define subgroups of triple negative breast cancer.
R Joseph Bender, Feilim Mac Gabhann.
PLoS One, 2013 May 15; 8(5). PMID: 23667446    Free PMC article.
A simple and reproducible breast cancer prognostic test.
Luigi Marchionni, Bahman Afsari, Donald Geman, Jeffrey T Leek.
BMC Genomics, 2013 May 21; 14. PMID: 23682826    Free PMC article.
Combined targeting of mTOR and AKT is an effective strategy for basal-like breast cancer in patient-derived xenograft models.
Siguang Xu, Shunqiang Li, +3 authors, Cynthia X Ma.
Mol Cancer Ther, 2013 May 22; 12(8). PMID: 23689832    Free PMC article.
Lactate dehydrogenase B: a metabolic marker of response to neoadjuvant chemotherapy in breast cancer.
Jennifer B Dennison, Jennifer R Molina, +9 authors, Gordon B Mills.
Clin Cancer Res, 2013 May 24; 19(13). PMID: 23697991    Free PMC article.
Prediction of lung cancer histological types by RT-qPCR gene expression in FFPE specimens.
Matthew D Wilkerson, Jason M Schallheim, +14 authors, Philip S Bernard.
J Mol Diagn, 2013 May 25; 15(4). PMID: 23701907    Free PMC article.
Classifications within molecular subtypes enables identification of BRCA1/BRCA2 mutation carriers by RNA tumor profiling.
Martin J Larsen, Torben A Kruse, +8 authors, Mads Thomassen.
PLoS One, 2013 May 25; 8(5). PMID: 23704984    Free PMC article.
Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis.
Amy S Farrell, Carl Pelz, +8 authors, Rosalie C Sears.
Mol Cell Biol, 2013 May 30; 33(15). PMID: 23716601    Free PMC article.
A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models.
Xiaomei Zhang, Sofie Claerhout, +26 authors, Michael T Lewis.
Cancer Res, 2013 Jun 06; 73(15). PMID: 23737486    Free PMC article.
Highly Cited.
Digital quantification of gene expression in sequential breast cancer biopsies reveals activation of an immune response.
Rinath M Jeselsohn, Lillian Werner, +11 authors, Steven E Come.
PLoS One, 2013 Jun 07; 8(5). PMID: 23741308    Free PMC article.
Prolactin-induced protein (PIP) regulates proliferation of luminal A type breast cancer cells in an estrogen-independent manner.
Sanjeev K Baniwal, Nyam-Osor Chimge, +2 authors, Baruch Frenkel.
PLoS One, 2013 Jun 12; 8(6). PMID: 23755096    Free PMC article.
Translating next generation sequencing to practice: opportunities and necessary steps.
Sitharthan Kamalakaran, Vinay Varadan, +5 authors, Lyndsay N Harris.
Mol Oncol, 2013 Jun 19; 7(4). PMID: 23769412    Free PMC article.
Review.
Predicting drug responsiveness in human cancers using genetically engineered mice.
Jerry Usary, Wei Zhao, +14 authors, Charles M Perou.
Clin Cancer Res, 2013 Jun 20; 19(17). PMID: 23780888    Free PMC article.
BreastMark: an integrated approach to mining publicly available transcriptomic datasets relating to breast cancer outcome.
Stephen F Madden, Colin Clarke, +5 authors, William M Gallagher.
Breast Cancer Res, 2013 Jul 04; 15(4). PMID: 23820017    Free PMC article.
Highly Cited.
Breast cancer subtyping by immunohistochemistry and histological grade outperforms breast cancer intrinsic subtypes in predicting neoadjuvant chemotherapy response.
E H Lips, L Mulder, +5 authors, J Wesseling.
Breast Cancer Res Treat, 2013 Jul 06; 140(1). PMID: 23828499    Free PMC article.
An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers.
Steven A Roberts, Michael S Lawrence, +12 authors, Dmitry A Gordenin.
Nat Genet, 2013 Jul 16; 45(9). PMID: 23852170    Free PMC article.
Highly Cited.
A conceptual and methodological framework for investigating etiologic heterogeneity.
Colin B Begg, Emily C Zabor, +3 authors, Venkatraman E Seshan.
Stat Med, 2013 Jul 17; 32(29). PMID: 23857589    Free PMC article.
Corruption of the intra-gene DNA methylation architecture is a hallmark of cancer.
Thomas E Bartlett, Alexey Zaikin, +3 authors, Martin Widschwendter.
PLoS One, 2013 Jul 23; 8(7). PMID: 23874574    Free PMC article.
Genes dysregulated to different extent or oppositely in estrogen receptor-positive and estrogen receptor-negative breast cancers.
Xianxiao Zhou, Tongwei Shi, +6 authors, Zheng Guo.
PLoS One, 2013 Jul 23; 8(7). PMID: 23875016    Free PMC article.
Cellular iron metabolism in prognosis and therapy of breast cancer.
Suzy V Torti, Frank M Torti.
Crit Rev Oncog, 2013 Jul 25; 18(5). PMID: 23879588    Free PMC article.
Review.
Luminal breast cancer: from biology to treatment.
Michail Ignatiadis, Christos Sotiriou.
Nat Rev Clin Oncol, 2013 Jul 25; 10(9). PMID: 23881035
Review.
Risk factors for specific histopathological types of postmenopausal breast cancer in the NIH-AARP Diet and Health Study.
Sarah J Nyante, Cher M Dallal, +3 authors, Louise A Brinton.
Am J Epidemiol, 2013 Aug 01; 178(3). PMID: 23899816    Free PMC article.
The genomic map of breast cancer: which roads lead to better targeted therapies?
Justin M Balko, Thomas P Stricker, Carlos L Arteaga.
Breast Cancer Res, 2013 Aug 03; 15(4). PMID: 23905624    Free PMC article.
Review.
Assignment of tumor subtype by genomic testing and pathologic-based approximations: implications on patient's management and therapy selection.
A Romero, A Prat, +9 authors, M Martín.
Clin Transl Oncol, 2013 Aug 03; 16(4). PMID: 23907291
Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013.
A Goldhirsch, E P Winer, +5 authors, Panel members.
Ann Oncol, 2013 Aug 07; 24(9). PMID: 23917950    Free PMC article.
Highly Cited.
Thrombospondin-4 expression is activated during the stromal response to invasive breast cancer.
Amy E McCart Reed, Sarah Song, +5 authors, Peter T Simpson.
Virchows Arch, 2013 Aug 15; 463(4). PMID: 23942617
Differential response to neoadjuvant chemotherapy among 7 triple-negative breast cancer molecular subtypes.
Hiroko Masuda, Keith A Baggerly, +9 authors, Naoto T Ueno.
Clin Cancer Res, 2013 Aug 21; 19(19). PMID: 23948975    Free PMC article.
Highly Cited.
Difference in therapeutic response between basal and nonbasal triple-negative breast cancers.
François Bertucci, Pascal Finetti, Patrice Viens, Daniel Birnbaum.
Oncologist, 2013 Aug 21; 18(9). PMID: 23960187    Free PMC article.
Activation of MAPK pathways due to DUSP4 loss promotes cancer stem cell-like phenotypes in basal-like breast cancer.
Justin M Balko, Luis J Schwarz, +6 authors, Carlos L Arteaga.
Cancer Res, 2013 Aug 24; 73(20). PMID: 23966295    Free PMC article.
Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis.
J Chuck Harrell, Adam D Pfefferle, +7 authors, Charles M Perou.
Clin Exp Metastasis, 2013 Aug 27; 31(1). PMID: 23975155    Free PMC article.
Molecular and cellular heterogeneity in breast cancer: challenges for personalized medicine.
Ashley G Rivenbark, Siobhan M O'Connor, William B Coleman.
Am J Pathol, 2013 Sep 03; 183(4). PMID: 23993780    Free PMC article.
Review.
ErbB3 downregulation enhances luminal breast tumor response to antiestrogens.
Meghan M Morrison, Katherine Hutchinson, +13 authors, Rebecca S Cook.
J Clin Invest, 2013 Sep 04; 123(10). PMID: 23999432    Free PMC article.
Clinical and molecular characterization of HER2 amplified-pancreatic cancer.
Angela Chou, Nicola Waddell, +25 authors, Andrew V Biankin.
Genome Med, 2013 Sep 06; 5(8). PMID: 24004612    Free PMC article.
Genetic background may contribute to PAM50 gene expression breast cancer subtype assignments.
Ying Hu, Ling Bai, +5 authors, Kent W Hunter.
PLoS One, 2013 Sep 10; 8(8). PMID: 24015230    Free PMC article.
Role of HGF in epithelial-stromal cell interactions during progression from benign breast disease to ductal carcinoma in situ.
Patricia Casbas-Hernandez, Monica D'Arcy, +9 authors, Melissa A Troester.
Breast Cancer Res, 2013 Sep 13; 15(5). PMID: 24025166    Free PMC article.
The RasGAP gene, RASAL2, is a tumor and metastasis suppressor.
Sara Koenig McLaughlin, Sarah Naomi Olsen, +8 authors, Karen Cichowski.
Cancer Cell, 2013 Sep 14; 24(3). PMID: 24029233    Free PMC article.
Factors predicting late recurrence for estrogen receptor-positive breast cancer.
Ivana Sestak, Mitch Dowsett, +4 authors, Jack Cuzick.
J Natl Cancer Inst, 2013 Sep 14; 105(19). PMID: 24029245    Free PMC article.
Highly Cited.
Characterization of synergistic anti-cancer effects of docosahexaenoic acid and curcumin on DMBA-induced mammary tumorigenesis in mice.
Rafat A Siddiqui, Kevin A Harvey, +6 authors, Cary Mariash.
BMC Cancer, 2013 Sep 17; 13. PMID: 24034496    Free PMC article.
Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts.
Shunqiang Li, Dong Shen, +52 authors, Matthew J Ellis.
Cell Rep, 2013 Sep 24; 4(6). PMID: 24055055    Free PMC article.
Highly Cited.
Integrated genomic analysis of triple-negative breast cancers reveals novel microRNAs associated with clinical and molecular phenotypes and sheds light on the pathways they control.
Emanuele de Rinaldis, Patrycja Gazinska, +10 authors, Andrew Tutt.
BMC Genomics, 2013 Sep 26; 14. PMID: 24059244    Free PMC article.
Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers.
Giampaolo Bianchini, Lajos Pusztai, +16 authors, Luca Gianni.
Breast Cancer Res, 2013 Sep 26; 15(5). PMID: 24060333    Free PMC article.
Potential biomarkers of long-term benefit from single-agent trastuzumab or lapatinib in HER2-positive metastatic breast cancer.
Filippo Montemurro, Aleix Prat, +9 authors, Maurizio Scaltriti.
Mol Oncol, 2013 Oct 01; 8(1). PMID: 24075779    Free PMC article.
Genomic pathway analysis reveals that EZH2 and HDAC4 represent mutually exclusive epigenetic pathways across human cancers.
Adam L Cohen, Stephen R Piccolo, +4 authors, Andrea H Bild.
BMC Med Genomics, 2013 Oct 02; 6. PMID: 24079712    Free PMC article.
Genomic insights into triple-negative and HER2-positive breast cancers using isogenic model systems.
Prakriti Mudvari, Kazufumi Ohshiro, +2 authors, Rakesh Kumar.
PLoS One, 2013 Oct 03; 8(9). PMID: 24086418    Free PMC article.
The molecular diversity of Luminal A breast tumors.
Giovanni Ciriello, Rileen Sinha, +5 authors, Nikolaus Schultz.
Breast Cancer Res Treat, 2013 Oct 08; 141(3). PMID: 24096568    Free PMC article.
Presence of anaplastic lymphoma kinase in inflammatory breast cancer.
Fredika M Robertson, Emanuel F Petricoin Iii, +17 authors, Massimo Cristofanilli.
Springerplus, 2013 Oct 09; 2. PMID: 24102046    Free PMC article.
Clinical application of high-throughput genomic technologies for treatment selection in breast cancer.
Aaron R Hansen, Philippe L Bedard.
Breast Cancer Res, 2013 Oct 19; 15(5). PMID: 24135425    Free PMC article.
Review.
Benefit risk assessment and update on the use of docetaxel in the management of breast cancer.
Scheryll Alken, Catherine M Kelly.
Cancer Manag Res, 2013 Oct 22; 5. PMID: 24143122    Free PMC article.
Review.
Differential activation of Wnt-β-catenin pathway in triple negative breast cancer increases MMP7 in a PTEN dependent manner.
Nandini Dey, Brandon Young, +4 authors, Brian Leyland-Jones.
PLoS One, 2013 Oct 22; 8(10). PMID: 24143235    Free PMC article.
Expression of microRNA-497 and its prognostic significance in human breast cancer.
Shaohua Wang, Hanjun Li, Jingjie Wang, Dan Wang.
Diagn Pathol, 2013 Oct 23; 8. PMID: 24143964    Free PMC article.
Neoadjuvant chemotherapy adaptation and serial MRI response monitoring in ER-positive HER2-negative breast cancer.
L S Rigter, C E Loo, +11 authors, S Rodenhuis.
Br J Cancer, 2013 Oct 24; 109(12). PMID: 24149178    Free PMC article.
High expression of ZNF703 independent of amplification indicates worse prognosis in patients with luminal B breast cancer.
Inga Reynisdottir, Adalgeir Arason, +14 authors, Rosa Bjork Barkardottir.
Cancer Med, 2013 Oct 25; 2(4). PMID: 24156016    Free PMC article.
The EndoPredict score provides prognostic information on late distant metastases in ER+/HER2- breast cancer patients.
P Dubsky, J C Brase, +18 authors, Austrian Breast and Colorectal Cancer Study Group (ABCSG).
Br J Cancer, 2013 Oct 26; 109(12). PMID: 24157828    Free PMC article.
Highly Cited.
Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes.
Aleix Prat, Olga Karginova, +8 authors, Charles M Perou.
Breast Cancer Res Treat, 2013 Oct 29; 142(2). PMID: 24162158    Free PMC article.
Highly Cited.
PROGgene: gene expression based survival analysis web application for multiple cancers.
Chirayu Pankaj Goswami, Harikrishna Nakshatri.
J Clin Bioinforma, 2013 Oct 30; 3(1). PMID: 24165311    Free PMC article.
Highly Cited.
Modeling precision treatment of breast cancer.
Anneleen Daemen, Obi L Griffith, +24 authors, Joe W Gray.
Genome Biol, 2013 Nov 02; 14(10). PMID: 24176112    Free PMC article.
Highly Cited.
Role of aldo-keto reductase family 1 (AKR1) enzymes in human steroid metabolism.
Tea Lanišnik Rižner, Trevor M Penning.
Steroids, 2013 Nov 06; 79. PMID: 24189185    Free PMC article.
Review.
Infrequent loss of luminal differentiation in ductal breast cancer metastasis.
Julia Calvo, Lourdes Sánchez-Cid, +3 authors, Pedro L Fernández.
PLoS One, 2013 Nov 10; 8(10). PMID: 24205108    Free PMC article.
Wnt signaling in triple negative breast cancer is associated with metastasis.
Nandini Dey, Benjamin G Barwick, +11 authors, Brian R Leyland-Jones.
BMC Cancer, 2013 Nov 12; 13. PMID: 24209998    Free PMC article.
Highly Cited.
Differential methylation relative to breast cancer subtype and matched normal tissue reveals distinct patterns.
Sabrina A Bardowell, Joel Parker, +3 authors, Theresa Swift-Scanlan.
Breast Cancer Res Treat, 2013 Nov 12; 142(2). PMID: 24212716    Free PMC article.
Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine.
Charlotte L T Jørgensen, Bent Ejlertsen, +3 authors, Kirsten V Nielsen.
BMC Cancer, 2013 Nov 13; 13. PMID: 24215511    Free PMC article.
Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts.
Adam D Pfefferle, Jason I Herschkowitz, +9 authors, Charles M Perou.
Genome Biol, 2013 Nov 14; 14(11). PMID: 24220145    Free PMC article.
Highly Cited.
Clinical studies examining the impact of obesity on breast cancer risk and prognosis.
Rishi Jain, Howard D Strickler, Eugene Fine, Joseph A Sparano.
J Mammary Gland Biol Neoplasia, 2013 Nov 14; 18(3-4). PMID: 24221746
Review.
Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration.
Lisa M McShane, Margaret M Cavenagh, +12 authors, Barbara A Conley.
BMC Med, 2013 Nov 16; 11. PMID: 24228635    Free PMC article.
Molecular profiling for breast cancer: a comprehensive review.
Muaiad Kittaneh, Alberto J Montero, Stefan Glück.
Biomark Cancer, 2013 Nov 20; 5. PMID: 24250234    Free PMC article.
Review.
An unmet need: tailoring extended adjuvant endocrine therapy.
G Bianchini, L Gianni.
Br J Cancer, 2013 Nov 21; 109(12). PMID: 24253504    Free PMC article.
Predicting degree of benefit from adjuvant trastuzumab in NSABP trial B-31.
Katherine L Pogue-Geile, Chungyeul Kim, +26 authors, Soonmyung Paik.
J Natl Cancer Inst, 2013 Nov 23; 105(23). PMID: 24262440    Free PMC article.
Genomic aberrations in the FGFR pathway: opportunities for targeted therapies in solid tumors.
R Dienstmann, J Rodon, +7 authors, J Tabernero.
Ann Oncol, 2013 Nov 23; 25(3). PMID: 24265351    Free PMC article.
Highly Cited. Review.
MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ERα)-positive mammary adenocarcinomas.
Malini Mukherjee, Gouqing Ge, +6 authors, Debananda Pati.
Oncogene, 2013 Nov 28; 33(48). PMID: 24276237    Free PMC article.
Biomarkers for Basal-like Breast Cancer.
Jennifer R Choo, Torsten O Nielsen.
Cancers (Basel), 2010 Jan 01; 2(2). PMID: 24281106    Free PMC article.
27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology.
Erik R Nelson, Suzanne E Wardell, +10 authors, Donald P McDonnell.
Science, 2013 Nov 30; 342(6162). PMID: 24288332    Free PMC article.
Highly Cited.
Prevalence and risk factors of bone metastasis and skeletal related events in patients with primary breast cancer in Japan.
Hiroyasu Yamashiro, Masahiro Takada, +22 authors, Masakazu Toi.
Int J Clin Oncol, 2013 Dec 03; 19(5). PMID: 24292334
Characterizing the heterogeneity of triple-negative breast cancers using microdissected normal ductal epithelium and RNA-sequencing.
Milan Radovich, Susan E Clare, +24 authors, Bryan P Schneider.
Breast Cancer Res Treat, 2013 Dec 03; 143(1). PMID: 24292813    Free PMC article.
Gene expression profiles of inflammatory breast cancer: correlation with response to neoadjuvant chemotherapy and metastasis-free survival.
F Bertucci, N T Ueno, +16 authors, S J Van Laere.
Ann Oncol, 2013 Dec 05; 25(2). PMID: 24299959    Free PMC article.
Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins.
Jacob J Kennedy, Susan E Abbatiello, +18 authors, Amanda G Paulovich.
Nat Methods, 2013 Dec 10; 11(2). PMID: 24317253    Free PMC article.
Highly Cited.
A collaborative study of the etiology of breast cancer subtypes in African American women: the AMBER consortium.
Julie R Palmer, Christine B Ambrosone, Andrew F Olshan.
Cancer Causes Control, 2013 Dec 18; 25(3). PMID: 24343304    Free PMC article.
A prognostic gene signature for metastasis-free survival of triple negative breast cancer patients.
Unjin Lee, Casey Frankenberger, +6 authors, Marsha Rich Rosner.
PLoS One, 2013 Dec 19; 8(12). PMID: 24349199    Free PMC article.
Long-term treatment efficacy in primary inflammatory breast cancer by hormonal receptor- and HER2-defined subtypes.
H Masuda, T M Brewer, +13 authors, N T Ueno.
Ann Oncol, 2013 Dec 20; 25(2). PMID: 24351399    Free PMC article.
Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets.
Justin M Balko, Jennifer M Giltnane, +24 authors, Carlos L Arteaga.
Cancer Discov, 2013 Dec 21; 4(2). PMID: 24356096    Free PMC article.
Highly Cited.
Magnetic resonance metabolic profiling of breast cancer tissue obtained with core needle biopsy for predicting pathologic response to neoadjuvant chemotherapy.
Ji Soo Choi, Hyeon-Man Baek, +5 authors, Youn Ki Nam.
PLoS One, 2013 Dec 25; 8(12). PMID: 24367616    Free PMC article.
An internally and externally validated prognostic score for metastatic breast cancer: analysis of 2269 patients.
A C Regierer, R Wolters, +7 authors, M B Wischnewsky.
Ann Oncol, 2013 Dec 26; 25(3). PMID: 24368402    Free PMC article.
AGO Recommendations for Diagnosis and Treatment of Patients with Early Breast Cancer: Update 2013.
Anton Scharl, Christoph Thomssen, Nadia Harbeck, Volkmar Müller.
Breast Care (Basel), 2014 Jan 15; 8(3). PMID: 24415966    Free PMC article.
Candidate luminal B breast cancer genes identified by genome, gene expression and DNA methylation profiling.
Stéphanie Cornen, Arnaud Guille, +16 authors, Max Chaffanet.
PLoS One, 2014 Jan 15; 9(1). PMID: 24416132    Free PMC article.
Breast Cancer Biomarkers: Utility in Clinical Practice.
Fanny Le Du, Naoto T Ueno, Ana M Gonzalez-Angulo.
Curr Breast Cancer Rep, 2014 Jan 15; 5(4). PMID: 24416469    Free PMC article.
Induction of Wnt-inducible signaling protein-1 correlates with invasive breast cancer oncogenesis and reduced type 1 cell-mediated cytotoxic immunity: a retrospective study.
David J Klinke.
PLoS Comput Biol, 2014 Jan 16; 10(1). PMID: 24426833    Free PMC article.
Long-term impact of the 70-gene signature on breast cancer outcome.
C A Drukker, H van Tinteren, +4 authors, L J Van't Veer.
Breast Cancer Res Treat, 2014 Jan 22; 143(3). PMID: 24445566    Free PMC article.
RNA profiling reveals familial aggregation of molecular subtypes in non-BRCA1/2 breast cancer families.
Martin J Larsen, Mads Thomassen, +6 authors, Anne-Marie Gerdes.
BMC Med Genomics, 2014 Feb 01; 7. PMID: 24479546    Free PMC article.
Molecular tests as prognostic factors in breast cancer.
Marc J van de Vijver.
Virchows Arch, 2014 Feb 04; 464(3). PMID: 24487789
Review.
Integrated genomic and epigenomic analysis of breast cancer brain metastasis.
Bodour Salhia, Jeff Kiefer, +19 authors, Nhan L Tran.
PLoS One, 2014 Feb 04; 9(1). PMID: 24489661    Free PMC article.
Multiclass prediction with partial least square regression for gene expression data: applications in breast cancer intrinsic taxonomy.
Chi-Cheng Huang, Shih-Hsin Tu, +3 authors, Eric Y Chuang.
Biomed Res Int, 2014 Feb 04; 2013. PMID: 24490149    Free PMC article.
SAP domain-dependent Mkl1 signaling stimulates proliferation and cell migration by induction of a distinct gene set indicative of poor prognosis in breast cancer patients.
Irem Gurbuz, Jacqueline Ferralli, +2 authors, Maria B Asparuhova.
Mol Cancer, 2014 Feb 06; 13. PMID: 24495796    Free PMC article.
Breast tumor subgroups reveal diverse clinical prognostic power.
Zhaoqi Liu, Xiang-Sun Zhang, Shihua Zhang.
Sci Rep, 2014 Feb 07; 4. PMID: 24499868    Free PMC article.
Development and validation of a gene expression score that predicts response to fulvestrant in breast cancer patients.
Steen Knudsen, Thomas Jensen, +5 authors, Elizabeth Anderson.
PLoS One, 2014 Feb 08; 9(2). PMID: 24505287    Free PMC article.
Gene co-expression modules as clinically relevant hallmarks of breast cancer diversity.
Denise M Wolf, Marc E Lenburg, +2 authors, Laura J van 't Veer.
PLoS One, 2014 Feb 12; 9(2). PMID: 24516633    Free PMC article.
Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology.
Jeffrey S Damrauer, Katherine A Hoadley, +8 authors, William Y Kim.
Proc Natl Acad Sci U S A, 2014 Feb 13; 111(8). PMID: 24520177    Free PMC article.
Highly Cited.
Intrinsic subtypes from PAM50 gene expression assay in a population-based breast cancer cohort: differences by age, race, and tumor characteristics.
Carol Sweeney, Philip S Bernard, +11 authors, Bette J Caan.
Cancer Epidemiol Biomarkers Prev, 2014 Feb 14; 23(5). PMID: 24521995    Free PMC article.
Intrinsic subtypes from the PAM50 gene expression assay in a population-based breast cancer survivor cohort: prognostication of short- and long-term outcomes.
Bette J Caan, Carol Sweeney, +8 authors, Philip S Bernard.
Cancer Epidemiol Biomarkers Prev, 2014 Feb 14; 23(5). PMID: 24521998    Free PMC article.
Long-term outcome of neoadjuvant endocrine therapy with aromatase inhibitors in elderly women with hormone receptor-positive breast cancer.
Antonino Grassadonia, Marta Di Nicola, +14 authors, Ettore Cianchetti.
Ann Surg Oncol, 2014 Feb 14; 21(5). PMID: 24522992    Free PMC article.
Radiation-induced gene signature predicts pathologic complete response to neoadjuvant chemotherapy in breast cancer patients.
Daniel S Oh, Maggie C U Cheang, Cheng Fan, Charles M Perou.
Radiat Res, 2014 Feb 18; 181(2). PMID: 24527691    Free PMC article.
Genomic profiling in luminal breast cancer.
Oleg Gluz, Daniel Hofmann, +3 authors, Nadia Harbeck.
Breast Care (Basel), 2014 Feb 20; 8(6). PMID: 24550749    Free PMC article.
Review.
Breast cancer subtype specific classifiers of response to neoadjuvant chemotherapy do not outperform classifiers trained on all subtypes.
Jorma J de Ronde, Marc Jan Bonder, +2 authors, Lodewyk F A Wessels.
PLoS One, 2014 Feb 22; 9(2). PMID: 24558399    Free PMC article.
Clinicopathologic features of triple negative breast cancers: an experience from Pakistan.
Atif Ali Hashmi, Muhammad Muzzammil Edhi, +3 authors, Mehmood Khan.
Diagn Pathol, 2014 Mar 04; 9. PMID: 24581278    Free PMC article.
A core invasiveness gene signature reflects epithelial-to-mesenchymal transition but not metastatic potential in breast cancer cell lines and tissue samples.
Melike Marsan, Gert Van den Eynden, +7 authors, Steven J Van Laere.
PLoS One, 2014 Mar 04; 9(2). PMID: 24586640    Free PMC article.
Race and breast cancer survival by intrinsic subtype based on PAM50 gene expression.
Candyce H Kroenke, Carol Sweeney, +8 authors, Bette J Caan.
Breast Cancer Res Treat, 2014 Mar 08; 144(3). PMID: 24604094    Free PMC article.
ClearCode34: A prognostic risk predictor for localized clear cell renal cell carcinoma.
Samira A Brooks, A Rose Brannon, +12 authors, W Kimryn Rathmell.
Eur Urol, 2014 Mar 13; 66(1). PMID: 24613583    Free PMC article.
Highly Cited.
Nottingham Prognostic Index Plus (NPI+): a modern clinical decision making tool in breast cancer.
E A Rakha, D Soria, +6 authors, I O Ellis.
Br J Cancer, 2014 Mar 13; 110(7). PMID: 24619074    Free PMC article.
Analytical validation of the PAM50-based Prosigna Breast Cancer Prognostic Gene Signature Assay and nCounter Analysis System using formalin-fixed paraffin-embedded breast tumor specimens.
Torsten Nielsen, Brett Wallden, +7 authors, James Storhoff.
BMC Cancer, 2014 Mar 15; 14. PMID: 24625003    Free PMC article.
Highly Cited.
Functional proteomic analysis reveals the involvement of KIAA1199 in breast cancer growth, motility and invasiveness.
Mohammad-Saeid Jami, Jinxuan Hou, +12 authors, Shi-Jian Ding.
BMC Cancer, 2014 Mar 19; 14. PMID: 24628760    Free PMC article.
Baseline staging tests based on molecular subtype is necessary for newly diagnosed breast cancer.
Xuesong Chen, Lichun Sun, +8 authors, Xiaoqun Dong.
J Exp Clin Cancer Res, 2014 Mar 19; 33. PMID: 24628817    Free PMC article.
Multi-level gene expression signatures, but not binary, outperform Ki67 for the long term prognostication of breast cancer patients.
Nicholas P Tobin, Linda S Lindström, +3 authors, Kristian Wennmalm.
Mol Oncol, 2014 Mar 19; 8(3). PMID: 24630985    Free PMC article.
A microRNA signature associated with early recurrence in breast cancer.
Luis G Pérez-Rivas, José M Jerez, +9 authors, José Lozano.
PLoS One, 2014 Mar 19; 9(3). PMID: 24632820    Free PMC article.
Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression.
Janna K Mouw, Yoshihiro Yui, +10 authors, Valerie M Weaver.
Nat Med, 2014 Mar 19; 20(4). PMID: 24633304    Free PMC article.
Highly Cited.
Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status.
Xi Zhao, Einar Andreas Rødland, +5 authors, Anne-Lise Børresen-Dale.
BMC Cancer, 2014 Mar 22; 14. PMID: 24645668    Free PMC article.
Tissue specific DNA methylation in normal human breast epithelium and in breast cancer.
Ayelet Avraham, Sean Soonweng Cho, +9 authors, Ella Evron.
PLoS One, 2014 Mar 22; 9(3). PMID: 24651077    Free PMC article.
Adaptive designs for clinical trials assessing biomarker-guided treatment strategies.
J Wason, A Marshall, +2 authors, N Stallard.
Br J Cancer, 2014 Mar 29; 110(8). PMID: 24667651    Free PMC article.
Identification of intrinsic imaging phenotypes for breast cancer tumors: preliminary associations with gene expression profiles.
Ahmed Bilal Ashraf, Dania Daye, +4 authors, Despina Kontos.
Radiology, 2014 Apr 08; 272(2). PMID: 24702725    Free PMC article.
Clinical validation of the EndoPredict test in node-positive, chemotherapy-treated ER+/HER2- breast cancer patients: results from the GEICAM 9906 trial.
Miguel Martin, Jan C Brase, +15 authors, Alvaro Rodriguez-Lescure.
Breast Cancer Res, 2014 Apr 15; 16(2). PMID: 24725534    Free PMC article.
Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer.
F Al-Ejeh, P T Simpson, +12 authors, K K Khanna.
Oncogenesis, 2014 Apr 23; 3. PMID: 24752235    Free PMC article.
Tumor subtype-specific cancer-testis antigens as potential biomarkers and immunotherapeutic targets for cancers.
Jun Yao, Otavia L Caballero, +4 authors, Qi Zhao.
Cancer Immunol Res, 2014 Apr 26; 2(4). PMID: 24764584    Free PMC article.
Multigene Assays for Classification, Prognosis, and Prediction in Breast Cancer: a Critical Review on the Background and Clinical Utility.
P Sinn, S Aulmann, +6 authors, A Schneeweiss.
Geburtshilfe Frauenheilkd, 2014 Apr 29; 73(9). PMID: 24771945    Free PMC article.
Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer.
Christine Mehner, Alexandra Hockla, +3 authors, Evette S Radisky.
Oncotarget, 2014 May 09; 5(9). PMID: 24811362    Free PMC article.
Highly Cited.
MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.
Yubao Wang, Young-Mi Lee, +15 authors, Jean J Zhao.
Elife, 2014 May 23; 3. PMID: 24844244    Free PMC article.
Hypomethylation of the MMP7 promoter and increased expression of MMP7 distinguishes the basal-like breast cancer subtype from other triple-negative tumors.
Steven T Sizemore, Gina M Sizemore, +6 authors, Ruth A Keri.
Breast Cancer Res Treat, 2014 May 23; 146(1). PMID: 24847890    Free PMC article.
Relationship between chemotherapy and prognosis in different subtypes of node-negative breast cancer.
Xia Liu, Yong Guan, +5 authors, Yun Niu.
Tumour Biol, 2014 May 28; 35(9). PMID: 24863944
Molecular classification of breast cancer.
Darina Vuong, Peter T Simpson, +2 authors, Sunil R Lakhani.
Virchows Arch, 2014 Jun 01; 465(1). PMID: 24878755
Molecular biology of brain metastasis.
Konstantina A Svokos, Bodour Salhia, Steven A Toms.
Int J Mol Sci, 2014 Jun 01; 15(6). PMID: 24879524    Free PMC article.
Review.
Polarity gene alterations in pure invasive micropapillary carcinomas of the breast.
Nadège Gruel, Vanessa Benhamo, +10 authors, Anne Vincent-Salomon.
Breast Cancer Res, 2014 Jun 03; 16(3). PMID: 24887297    Free PMC article.
A shared transcriptional program in early breast neoplasias despite genetic and clinical distinctions.
Alayne L Brunner, Jun Li, +6 authors, Robert B West.
Genome Biol, 2014 Jun 03; 15(5). PMID: 24887547    Free PMC article.
Comparison of RNA-Seq by poly (A) capture, ribosomal RNA depletion, and DNA microarray for expression profiling.
Wei Zhao, Xiaping He, +3 authors, Charles M Perou.
BMC Genomics, 2014 Jun 04; 15. PMID: 24888378    Free PMC article.
Highly Cited.
Nuclear CSPP1 expression defined subtypes of basal-like breast cancer.
J Sternemalm, H G Russnes, +6 authors, S Patzke.
Br J Cancer, 2014 Jun 06; 111(2). PMID: 24901235    Free PMC article.
Prognostic B-cell signatures using mRNA-seq in patients with subtype-specific breast and ovarian cancer.
Michael D Iglesia, Benjamin G Vincent, +4 authors, Jonathan S Serody.
Clin Cancer Res, 2014 Jun 12; 20(14). PMID: 24916698    Free PMC article.
Highly Cited.
Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation.
Sarah Phillips, Aleix Prat, +9 authors, Charlotte Kuperwasser.
Stem Cell Reports, 2014 Jun 18; 2(5). PMID: 24936451    Free PMC article.
Decreased expression of C10orf10 and its prognostic significance in human breast cancer.
Junjiang Deng, Yan Dong, +4 authors, Jianjun Li.
PLoS One, 2014 Jun 18; 9(6). PMID: 24936657    Free PMC article.
JARID1B is a luminal lineage-driving oncogene in breast cancer.
Shoji Yamamoto, Zhenhua Wu, +19 authors, Kornelia Polyak.
Cancer Cell, 2014 Jun 18; 25(6). PMID: 24937458    Free PMC article.
Highly Cited.
Chromosomal instability selects gene copy-number variants encoding core regulators of proliferation in ER+ breast cancer.
David Endesfelder, Rebecca Burrell, +6 authors, Maik Kschischo.
Cancer Res, 2014 Jun 28; 74(17). PMID: 24970479    Free PMC article.
A functional interplay between ZNF217 and estrogen receptor alpha exists in luminal breast cancers.
Nhan T Nguyen, Julie A Vendrell, +8 authors, Pascale A Cohen.
Mol Oncol, 2014 Jun 29; 8(8). PMID: 24973012    Free PMC article.
Validation of the prognostic gene portfolio, ClinicoMolecular Triad Classification, using an independent prospective breast cancer cohort and external patient populations.
Dong-Yu Wang, Susan J Done, David R Mc Cready, Wey L Leong.
Breast Cancer Res, 2014 Jul 06; 16(4). PMID: 24996446    Free PMC article.
iGPSe: a visual analytic system for integrative genomic based cancer patient stratification.
Hao Ding, Chao Wang, Kun Huang, Raghu Machiraju.
BMC Bioinformatics, 2014 Jul 09; 15. PMID: 25000928    Free PMC article.
TBCRC 018: phase II study of iniparib in combination with irinotecan to treat progressive triple negative breast cancer brain metastases.
Carey Anders, Allison M Deal, +21 authors, Lisa A Carey.
Breast Cancer Res Treat, 2014 Jul 09; 146(3). PMID: 25001612    Free PMC article.
Systematic analysis of metastasis-associated genes identifies miR-17-5p as a metastatic suppressor of basal-like breast cancer.
Meiyun Fan, Aarti Sethuraman, +2 authors, Lawrence M Pfeffer.
Breast Cancer Res Treat, 2014 Jul 09; 146(3). PMID: 25001613    Free PMC article.
Integrative genomic and transcriptomic characterization of papillary carcinomas of the breast.
Salvatore Piscuoglio, Charlotte K Y Ng, +10 authors, Jorge S Reis-Filho.
Mol Oncol, 2014 Jul 22; 8(8). PMID: 25041824    Free PMC article.
Proteogenomic characterization of human colon and rectal cancer.
Bing Zhang, Jing Wang, +21 authors, NCI CPTAC.
Nature, 2014 Jul 22; 513(7518). PMID: 25043054    Free PMC article.
Highly Cited.
Subtyping of triple-negative breast cancer: implications for therapy.
Vandana G Abramson, Brian D Lehmann, Tarah J Ballinger, Jennifer A Pietenpol.
Cancer, 2014 Jul 22; 121(1). PMID: 25043972    Free PMC article.
Highly Cited. Review.
Molecular features of the basal-like breast cancer subtype based on BRCA1 mutation status.
Aleix Prat, Cristina Cruz, +3 authors, Judith Balmaña.
Breast Cancer Res Treat, 2014 Jul 23; 147(1). PMID: 25048467    Free PMC article.
Diagnostic tests based on gene expression profile in breast cancer: from background to clinical use.
Laura Zanotti, Alberto Bottini, +2 authors, Maria Rosa Cappelletti.
Tumour Biol, 2014 Jul 23; 35(9). PMID: 25048969
Review.
Computational prognostic indicators for breast cancer.
Xinan Yang, Xindi Ai, John M Cunningham.
Cancer Manag Res, 2014 Jul 23; 6. PMID: 25050076    Free PMC article.
Review.
A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype.
Qing Cheng, Jeffrey T Chang, +4 authors, H Kim Lyerly.
Breast Cancer Res, 2014 Jul 26; 16(4). PMID: 25060555    Free PMC article.
TRIM24 links glucose metabolism with transformation of human mammary epithelial cells.
T N Pathiraja, K N Thakkar, +10 authors, M C Barton.
Oncogene, 2014 Jul 30; 34(22). PMID: 25065590    Free PMC article.
MicroRNA-18a inhibits hypoxia-inducible factor 1α activity and lung metastasis in basal breast cancers.
Raisa Krutilina, Wenlin Sun, +5 authors, Meiyun Fan.
Breast Cancer Res, 2014 Jul 30; 16(4). PMID: 25069832    Free PMC article.
p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition.
Jesse Hudson, Jacqueline R Ha, +10 authors, Josie Ursini-Siegel.
Mol Cell Biol, 2014 Jul 30; 34(19). PMID: 25071152    Free PMC article.
Identification of a novel luminal molecular subtype of breast cancer.
Anna Dvorkin-Gheva, John A Hassell.
PLoS One, 2014 Jul 31; 9(7). PMID: 25076125    Free PMC article.
The co-factor of LIM domains (CLIM/LDB/NLI) maintains basal mammary epithelial stem cells and promotes breast tumorigenesis.
Michael L Salmans, Zhengquan Yu, +5 authors, Bogi Andersen.
PLoS Genet, 2014 Aug 01; 10(7). PMID: 25079073    Free PMC article.
Evaluation of the ability of adjuvant tamoxifen-benefit gene signatures to predict outcome of hormone-naive estrogen receptor-positive breast cancer patients treated with tamoxifen in the advanced setting.
Anieta M Sieuwerts, Maria B Lyng, +6 authors, Henrik J Ditzel.
Mol Oncol, 2014 Aug 02; 8(8). PMID: 25081647    Free PMC article.
Comparison of gene expression patterns across 12 tumor types identifies a cancer supercluster characterized by TP53 mutations and cell cycle defects.
E Martínez, K Yoshihara, +3 authors, R G W Verhaak.
Oncogene, 2014 Aug 05; 34(21). PMID: 25088195    Free PMC article.
Delineation of a FOXA1/ERα/AGR2 regulatory loop that is dysregulated in endocrine therapy-resistant breast cancer.
Tricia M Wright, Suzanne E Wardell, +4 authors, Donald P McDonnell.
Mol Cancer Res, 2014 Aug 08; 12(12). PMID: 25100862    Free PMC article.
Microarray-based RNA profiling of breast cancer: batch effect removal improves cross-platform consistency.
Martin J Larsen, Mads Thomassen, +2 authors, Torben A Kruse.
Biomed Res Int, 2014 Aug 08; 2014. PMID: 25101291    Free PMC article.
Predicting response and survival in chemotherapy-treated triple-negative breast cancer.
A Prat, A Lluch, +35 authors, E Alba.
Br J Cancer, 2014 Aug 08; 111(8). PMID: 25101563    Free PMC article.
Biological subtypes of breast cancer: Prognostic and therapeutic implications.
Ozlem Yersal, Sabri Barutca.
World J Clin Oncol, 2014 Aug 13; 5(3). PMID: 25114856    Free PMC article.
Highly Cited. Review.
Adjuvant chemotherapy in breast cancer: To use or not to use, the anthracyclines.
Jennifer A Crozier, Abhisek Swaika, Alvaro Moreno-Aspitia.
World J Clin Oncol, 2014 Aug 13; 5(3). PMID: 25114866    Free PMC article.
Review.
How many etiological subtypes of breast cancer: two, three, four, or more?
William F Anderson, Philip S Rosenberg, +2 authors, Mark E Sherman.
J Natl Cancer Inst, 2014 Aug 15; 106(8). PMID: 25118203    Free PMC article.
Highly Cited. Review.
Characterization of type III TGF-β receptor expression in invasive breast carcinomas: a potential new marker and target for triple negative breast cancer.
Judy C Pang, Nilam K Virani, Kelley M Kidwell, Celina G Kleer.
J Cell Commun Signal, 2014 Aug 20; 8(3). PMID: 25135009    Free PMC article.
Molecular features and survival outcomes of the intrinsic subtypes within HER2-positive breast cancer.
Aleix Prat, Lisa A Carey, +6 authors, José Baselga.
J Natl Cancer Inst, 2014 Aug 21; 106(8). PMID: 25139534    Free PMC article.
Highly Cited.
Age-specific changes in intrinsic breast cancer subtypes: a focus on older women.
Emily O Jenkins, Allison M Deal, +4 authors, Hyman B Muss.
Oncologist, 2014 Aug 22; 19(10). PMID: 25142841    Free PMC article.
An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer.
Michael L Gatza, Grace O Silva, +2 authors, Charles M Perou.
Nat Genet, 2014 Aug 26; 46(10). PMID: 25151356    Free PMC article.
Highly Cited.
Cancer progression modeling using static sample data.
Yijun Sun, Jin Yao, Norma J Nowak, Steve Goodison.
Genome Biol, 2014 Aug 27; 15(8). PMID: 25155694    Free PMC article.
Gene Expression Analysis Reveals Distinct Pathways of Resistance to Bevacizumab in Xenograft Models of Human ER-Positive Breast Cancer.
Yesim Gökmen-Polar, Chirayu P Goswami, +9 authors, George W Sledge.
J Cancer, 2014 Aug 27; 5(8). PMID: 25157274    Free PMC article.
Genome-driven integrated classification of breast cancer validated in over 7,500 samples.
H Raza Ali, Oscar M Rueda, +4 authors, Carlos Caldas.
Genome Biol, 2014 Aug 29; 15(8). PMID: 25164602    Free PMC article.
Highly Cited.
Chemotherapy in early breast cancer: when, how and which one?
Marcus Schmidt.
Breast Care (Basel), 2014 Sep 02; 9(3). PMID: 25177256    Free PMC article.
Review.
Linking signaling pathways to transcriptional programs in breast cancer.
Hatice U Osmanbeyoglu, Raphael Pelossof, Jacqueline F Bromberg, Christina S Leslie.
Genome Res, 2014 Sep 04; 24(11). PMID: 25183703    Free PMC article.
Molecular subtyping predicts pathologic tumor response in early-stage breast cancer treated with neoadjuvant docetaxel plus capecitabine with or without trastuzumab chemotherapy.
Soley Bayraktar, Melanie Royce, +2 authors, Stefan Glück.
Med Oncol, 2014 Sep 05; 31(10). PMID: 25186065
Genome-based risk prediction for early stage breast cancer.
Christina Adaniel, Komal Jhaveri, Adriana Heguy, Francisco J Esteva.
Oncologist, 2014 Sep 05; 19(10). PMID: 25187476    Free PMC article.
Review.
The effects of soy supplementation on gene expression in breast cancer: a randomized placebo-controlled study.
Moshe Shike, Ashley S Doane, +7 authors, Larry Norton.
J Natl Cancer Inst, 2014 Sep 06; 106(9). PMID: 25190728    Free PMC article.
Microarray phosphatome profiling of breast cancer patients unveils a complex phosphatase regulatory role of the MAPK and PI3K pathways in estrogen receptor-negative breast cancers.
Ramon G Manzano, Elena M Martinez-Navarro, Jeronimo Forteza, Antonio Brugarolas.
Int J Oncol, 2014 Sep 10; 45(6). PMID: 25201346    Free PMC article.
The oncogenic potential of human cytomegalovirus and breast cancer.
Georges Herbein, Amit Kumar.
Front Oncol, 2014 Sep 10; 4. PMID: 25202681    Free PMC article.
Review.
Integrated miRNA and mRNA profiling of tumor-educated macrophages identifies prognostic subgroups in estrogen receptor-positive breast cancer.
Annalen Bleckmann, Andreas Leha, +6 authors, Florian Klemm.
Mol Oncol, 2014 Sep 11; 9(1). PMID: 25205039    Free PMC article.
Comprehensive genomic analysis identifies novel subtypes and targets of triple-negative breast cancer.
Matthew D Burstein, Anna Tsimelzon, +10 authors, Powel H Brown.
Clin Cancer Res, 2014 Sep 12; 21(7). PMID: 25208879    Free PMC article.
Highly Cited.
Preanalytical variables and performance of diagnostic RNA-based gene expression analysis in breast cancer.
Christopher Poremba, Jennifer Uhlendorff, +10 authors, Carsten Denkert.
Virchows Arch, 2014 Sep 15; 465(4). PMID: 25218890    Free PMC article.
Co-expression of MET and CD47 is a novel prognosticator for survival of luminal breast cancer patients.
Irène Baccelli, Albrecht Stenzinger, +11 authors, Andreas Trumpp.
Oncotarget, 2014 Sep 18; 5(18). PMID: 25230070    Free PMC article.
A general framework for analyzing tumor subclonality using SNP array and DNA sequencing data.
Bo Li, Jun Z Li.
Genome Biol, 2014 Sep 26; 15(9). PMID: 25253082    Free PMC article.
Effect of p95HER2/611CTF on the response to trastuzumab and chemotherapy.
Josep Lluís Parra-Palau, Beatriz Morancho, +14 authors, Joaquín Arribas.
J Natl Cancer Inst, 2014 Sep 26; 106(11). PMID: 25253614    Free PMC article.
Excess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivo.
S Winsel, J Mäki-Jouppila, +8 authors, M J Kallio.
Br J Cancer, 2014 Oct 01; 111(11). PMID: 25268374    Free PMC article.
Dynamic classification using case-specific training cohorts outperforms static gene expression signatures in breast cancer.
Balázs Győrffy, Thomas Karn, +3 authors, Lajos Pusztai.
Int J Cancer, 2014 Oct 03; 136(9). PMID: 25274406    Free PMC article.
Claudin-low breast cancers: clinical, pathological, molecular and prognostic characterization.
Renaud Sabatier, Pascal Finetti, +5 authors, François Bertucci.
Mol Cancer, 2014 Oct 04; 13. PMID: 25277734    Free PMC article.
Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis.
Sergey V Novitskiy, Elizabeth Forrester, +10 authors, Harold L Moses.
Breast Cancer Res, 2014 Oct 05; 16(5). PMID: 25280532    Free PMC article.
Dual specificity phosphatase 4 gene expression in association with triple-negative breast cancer outcome.
Michelle L Baglia, Qiuyin Cai, +10 authors, Xiao-Ou Shu.
Breast Cancer Res Treat, 2014 Oct 05; 148(1). PMID: 25281216    Free PMC article.
DNA methylation profiling in the Carolina Breast Cancer Study defines cancer subclasses differing in clinicopathologic characteristics and survival.
Kathleen Conway, Sharon N Edmiston, +8 authors, Robert C Millikan.
Breast Cancer Res, 2014 Oct 08; 16(5). PMID: 25287138    Free PMC article.
Statistical measures of transcriptional diversity capture genomic heterogeneity of cancer.
Tingting Jiang, Weiwei Shi, +5 authors, Christos Hatzis.
BMC Genomics, 2014 Oct 09; 15. PMID: 25294321    Free PMC article.
Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes.
Xiaoping Su, Gabriel G Malouf, +8 authors, Francisco J Esteva.
Oncotarget, 2014 Oct 10; 5(20). PMID: 25296969    Free PMC article.
Highly Cited.
An optical labeling-based proliferation assay system reveals the paracrine effect of interleukin-6 in breast cancer.
Junji Itou, Sunao Tanaka, +3 authors, Masakazu Toi.
Biochim Biophys Acta, 2014 Oct 12; 1853(1). PMID: 25305574    Free PMC article.
Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K.
Jeff C Liu, Veronique Voisin, +10 authors, Eldad Zacksenhaus.
EMBO Mol Med, 2014 Oct 22; 6(12). PMID: 25330770    Free PMC article.
Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity.
Debora Soncini, Irene Caffa, +19 authors, Alessio Nencioni.
J Biol Chem, 2014 Oct 22; 289(49). PMID: 25331943    Free PMC article.
BCCTBbp: the Breast Cancer Campaign Tissue Bank bioinformatics portal.
Rosalind J Cutts, José Afonso Guerra-Assunção, +2 authors, Claude Chelala.
Nucleic Acids Res, 2014 Oct 22; 43(Database issue). PMID: 25332396    Free PMC article.
Development of a robust RNA-based classifier to accurately determine ER, PR, and HER2 status in breast cancer clinical samples.
Timothy R Wilson, Yuanyuan Xiao, +13 authors, Mark R Lackner.
Breast Cancer Res Treat, 2014 Oct 23; 148(2). PMID: 25338319    Free PMC article.
Differentiation and loss of malignant character of spontaneous pulmonary metastases in patient-derived breast cancer models.
Jessica Bockhorn, Aleix Prat, +9 authors, Huiping Liu.
Cancer Res, 2014 Oct 24; 74(24). PMID: 25339353    Free PMC article.
Standard of care and promising new agents for triple negative metastatic breast cancer.
Patrizia Mancini, Antonio Angeloni, +2 authors, Silvia Mezi.
Cancers (Basel), 2014 Oct 28; 6(4). PMID: 25347122    Free PMC article.
Review.
Cutting the brakes and flooring the gas: how TMEPAI turns TGF-β into a tumor promoter.
Magdalena A Cichon, Derek C Radisky.
Genes Cancer, 2014 Oct 30; 5(9-10). PMID: 25352947    Free PMC article.
Estrogen receptor expression is high but is of lower intensity in tubular carcinoma than in well-differentiated invasive ductal carcinoma.
Julie M Jorns, Dafydd G Thomas, +7 authors, Daniel W Visscher.
Arch Pathol Lab Med, 2014 Oct 31; 138(11). PMID: 25357113    Free PMC article.
Vascular endothelial growth factor C promotes breast cancer progression via a novel antioxidant mechanism that involves regulation of superoxide dismutase 3.
Chu-An Wang, J Chuck Harrell, +2 authors, Heide L Ford.
Breast Cancer Res, 2014 Nov 02; 16(5). PMID: 25358638    Free PMC article.
Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer.
Li Zhang, Lisheng Deng, +5 authors, Yongcheng Song.
Oncotarget, 2014 Nov 02; 5(21). PMID: 25359765    Free PMC article.
Molecular subtype and tumor characteristics of breast cancer metastases as assessed by gene expression significantly influence patient post-relapse survival.
N P Tobin, J C Harrell, +14 authors, TEX Trialists Group.
Ann Oncol, 2014 Nov 02; 26(1). PMID: 25361981    Free PMC article.
Hereditary breast cancer: clinical, pathological and molecular characteristics.
Martin J Larsen, Mads Thomassen, Anne-Marie Gerdes, Torben A Kruse.
Breast Cancer (Auckl), 2014 Nov 05; 8. PMID: 25368521    Free PMC article.
Review.
An ER-associated miRNA signature predicts prognosis in ER-positive breast cancer.
Xin Zhou, Xiaping Wang, +3 authors, Ping Liu.
J Exp Clin Cancer Res, 2014 Nov 07; 33. PMID: 25373603    Free PMC article.
A pan-cancer modular regulatory network analysis to identify common and cancer-specific network components.
Sara A Knaack, Alireza Fotuhi Siahpirani, Sushmita Roy.
Cancer Inform, 2014 Nov 07; 13(Suppl 5). PMID: 25374456    Free PMC article.
Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state.
Yarden Katz, Feifei Li, +9 authors, Christopher B Burge.
Elife, 2014 Nov 08; 3. PMID: 25380226    Free PMC article.
Wip1 phosphatase in breast cancer.
A Emelyanov, D V Bulavin.
Oncogene, 2014 Nov 11; 34(34). PMID: 25381821
Review.
Loss of estrogen-regulated microRNA expression increases HER2 signaling and is prognostic of poor outcome in luminal breast cancer.
Shannon T Bailey, Thomas Westerling, Myles Brown.
Cancer Res, 2014 Nov 13; 75(2). PMID: 25388283    Free PMC article.
Lymphovascular invasion and histologic grade are associated with specific genomic profiles in invasive carcinomas of the breast.
Felipe Fidalgo, Tatiane Cristina Rodrigues, +6 authors, Ana Cristina Victorino Krepischi.
Tumour Biol, 2014 Nov 14; 36(3). PMID: 25391423    Free PMC article.
Pathological non-response to chemotherapy in a neoadjuvant setting of breast cancer: an inter-institutional study.
D Balmativola, C Marchiò, +26 authors, A Sapino.
Breast Cancer Res Treat, 2014 Nov 15; 148(3). PMID: 25395316    Free PMC article.
Transfer of clinically relevant gene expression signatures in breast cancer: from Affymetrix microarray to Illumina RNA-Sequencing technology.
Debora Fumagalli, Alexis Blanchet-Cohen, +13 authors, Benjamin Haibe-Kains.
BMC Genomics, 2014 Nov 22; 15. PMID: 25412710    Free PMC article.
Metaplastic breast carcinomas display genomic and transcriptomic heterogeneity [corrected]. .
Britta Weigelt, Charlotte K Y Ng, +8 authors, Jorge S Reis-Filho.
Mod Pathol, 2014 Nov 22; 28(3). PMID: 25412848    Free PMC article.
Dual roles for immune metagenes in breast cancer prognosis and therapy prediction.
Angela Alistar, Jeff W Chou, +3 authors, Lance D Miller.
Genome Med, 2014 Nov 25; 6(10). PMID: 25419236    Free PMC article.
Molecular Heterogeneity of Triple Negative Breast Cancer.
Vandana G Abramson, Ingrid A Mayer.
Curr Breast Cancer Rep, 2014 Nov 25; 6(3). PMID: 25419441    Free PMC article.
Estrogen independent gene expression defines clinically relevant subgroups of estrogen receptor positive breast cancer.
Robin M Hallett, John A Hassell.
BMC Cancer, 2014 Nov 26; 14. PMID: 25420785    Free PMC article.
Expression profiling of circulating tumor cells in metastatic breast cancer.
Julie E Lang, Janet H Scott, +11 authors, John W Park.
Breast Cancer Res Treat, 2014 Nov 30; 149(1). PMID: 25432738    Free PMC article.
E2F4 regulatory program predicts patient survival prognosis in breast cancer.
Sari S Khaleel, Erik H Andrews, +2 authors, Chao Cheng.
Breast Cancer Res, 2014 Dec 03; 16(6). PMID: 25440089    Free PMC article.
Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells.
Debangshu Samanta, Daniele M Gilkes, +2 authors, Gregg L Semenza.
Proc Natl Acad Sci U S A, 2014 Dec 03; 111(50). PMID: 25453096    Free PMC article.
Highly Cited.
Tumor intrinsic subtype is reflected in cancer-adjacent tissue.
Patricia Casbas-Hernandez, Xuezheng Sun, +9 authors, Melissa A Troester.
Cancer Epidemiol Biomarkers Prev, 2014 Dec 04; 24(2). PMID: 25465802    Free PMC article.
A DNA methylation-based definition of biologically distinct breast cancer subtypes.
Olafur A Stefansson, Sebastian Moran, +9 authors, Manel Esteller.
Mol Oncol, 2014 Dec 04; 9(3). PMID: 25468711    Free PMC article.
Highly Cited.
Inclusion of KI67 significantly improves performance of the PREDICT prognostication and prediction model for early breast cancer.
Gordon C Wishart, Emad Rakha, +6 authors, Paul D P Pharoah.
BMC Cancer, 2014 Dec 05; 14. PMID: 25472026    Free PMC article.
Making breast cancer molecular subtypes robust?
Johan Staaf, Markus Ringnér.
J Natl Cancer Inst, 2014 Dec 07; 107(1). PMID: 25479803    Free PMC article.
Emerging gene-based prognostic tools in early breast cancer: First steps to personalised medicine.
Umar Wazir, Kefah Mokbel.
World J Clin Oncol, 2014 Dec 11; 5(5). PMID: 25493218    Free PMC article.
Targeting SH2 domains in breast cancer.
Pietro Morlacchi, Fredika M Robertson, Jim Klostergaard, John S McMurray.
Future Med Chem, 2014 Dec 17; 6(17). PMID: 25495984    Free PMC article.
Review.
Genomic profiling of breast cancers.
Christina Curtis.
Curr Opin Obstet Gynecol, 2014 Dec 17; 27(1). PMID: 25502431    Free PMC article.
Review.
α-Tubulin acetylation elevated in metastatic and basal-like breast cancer cells promotes microtentacle formation, adhesion, and invasive migration.
Amanda E Boggs, Michele I Vitolo, +8 authors, Stuart S Martin.
Cancer Res, 2014 Dec 17; 75(1). PMID: 25503560    Free PMC article.
A new tumor biomarker, serum protein peak at 3,144 m/z, in patients with node-positive breast cancer.
Z Chen, S Xu, +6 authors, X Wang.
Clin Transl Oncol, 2014 Dec 17; 17(6). PMID: 25511546    Free PMC article.
Intrinsic subtypes, PIK3CA mutation, and the degree of benefit from adjuvant trastuzumab in the NSABP B-31 trial.
Katherine L Pogue-Geile, Nan Song, +13 authors, Soonmyung Paik.
J Clin Oncol, 2015 Jan 07; 33(12). PMID: 25559813    Free PMC article.
Emerging understanding of multiscale tumor heterogeneity.
Michael J Gerdes, Anup Sood, +3 authors, Fiona Ginty.
Front Oncol, 2015 Jan 08; 4. PMID: 25566504    Free PMC article.
Review.
BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells.
Walid T Khaled, Song Choon Lee, +15 authors, Pentao Liu.
Nat Commun, 2015 Jan 13; 6. PMID: 25574598    Free PMC article.
Highly Cited.
Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy.
Adam D Pfefferle, Benjamin T Spike, Geoff M Wahl, Charles M Perou.
Breast Cancer Res Treat, 2015 Jan 13; 149(2). PMID: 25575446    Free PMC article.
Intrinsic cancer subtypes--next steps into personalized medicine.
Cristina Santos, Rebeca Sanz-Pamplona, +6 authors, Ramon Salazar.
Cell Oncol (Dordr), 2015 Jan 15; 38(1). PMID: 25586691
Review.
Unsupervised feature construction and knowledge extraction from genome-wide assays of breast cancer with denoising autoencoders.
Jie Tan, Matthew Ung, Chao Cheng, Casey S Greene.
Pac Symp Biocomput, 2015 Jan 17;. PMID: 25592575    Free PMC article.
Expression profiling of migrated and invaded breast cancer cells predicts early metastatic relapse and reveals Krüppel-like factor 9 as a potential suppressor of invasive growth in breast cancer.
Ridha Limame, Ken Op de Beeck, +8 authors, Patrick Pauwels.
Oncoscience, 2015 Jan 17; 1(1). PMID: 25593984    Free PMC article.
Gene expression profiling of lobular carcinoma in situ reveals candidate precursor genes for invasion.
Victor P Andrade, Mary Morrogh, +12 authors, Tari A King.
Mol Oncol, 2015 Jan 21; 9(4). PMID: 25601220    Free PMC article.
miR-29b defines the pro-/anti-proliferative effects of S100A7 in breast cancer.
Helong Zhao, Tasha Wilkie, +5 authors, Ramesh K Ganju.
Mol Cancer, 2015 Jan 28; 14. PMID: 25622979    Free PMC article.
Endothelial follicle-stimulating hormone receptor expression in invasive breast cancer and vascular remodeling at tumor periphery.
François Planeix, Mohammad-Ahsan Siraj, +5 authors, Nicolae Ghinea.
J Exp Clin Cancer Res, 2015 Feb 06; 34. PMID: 25652007    Free PMC article.
Glycan-related gene expression signatures in breast cancer subtypes; relation to survival.
Ivan O Potapenko, Torben Lüders, +7 authors, Vilde D Haakensen.
Mol Oncol, 2015 Feb 07; 9(4). PMID: 25655580    Free PMC article.
Prognostic and predictive value of PDL1 expression in breast cancer.
Renaud Sabatier, Pascal Finetti, +7 authors, François Bertucci.
Oncotarget, 2015 Feb 12; 6(7). PMID: 25669979    Free PMC article.
Highly Cited.
MicroRNA let-7b regulates genomic balance by targeting Aurora B kinase.
Jenni Heidi Eveliina Mäki-Jouppila, Sofia Pruikkonen, +6 authors, Marko Johannes Kallio.
Mol Oncol, 2015 Feb 17; 9(6). PMID: 25682900    Free PMC article.
Role of microRNA221 in regulating normal mammary epithelial hierarchy and breast cancer stem-like cells.
Jia Ke, Zhiju Zhao, +18 authors, Suling Liu.
Oncotarget, 2015 Feb 18; 6(6). PMID: 25686829    Free PMC article.
Gene expression-based classifications of fibroadenomas and phyllodes tumours of the breast.
Maria Vidal, Vicente Peg, +5 authors, Aleix Prat.
Mol Oncol, 2015 Feb 18; 9(6). PMID: 25687451    Free PMC article.
Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.
Magdalena A Cichon, Celeste M Nelson, Derek C Radisky.
Cancer Inform, 2015 Feb 24; 14(Suppl 3). PMID: 25698877    Free PMC article.
Metastatic breast cancer: the potential of miRNA for diagnosis and treatment monitoring.
Andrew McGuire, James A L Brown, Michael J Kerin.
Cancer Metastasis Rev, 2015 Feb 28; 34(1). PMID: 25721950    Free PMC article.
Highly Cited. Review.
The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine.
Lao H Saal, Johan Vallon-Christersson, +16 authors, Åke Borg.
Genome Med, 2015 Feb 28; 7(1). PMID: 25722745    Free PMC article.
Study of integrated heterogeneous data reveals prognostic power of gene expression for breast cancer survival.
Richard E Neapolitan, Xia Jiang.
PLoS One, 2015 Feb 28; 10(2). PMID: 25723490    Free PMC article.
MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer.
Kirti Shukla, Ashwini Kumar Sharma, +8 authors, Stefan Wiemann.
Mol Oncol, 2015 Mar 04; 9(6). PMID: 25732226    Free PMC article.
Combining functional genomics strategies identifies modular heterogeneity of breast cancer intrinsic subtypes.
Nima Pouladi, Richard Cowper-Sallari, Jason H Moore.
BioData Min, 2014 Jan 01; 7. PMID: 25745517    Free PMC article.
Treatment-induced cell cycle kinetics dictate tumor response to chemotherapy.
Robin M Hallett, Cheng Huang, +5 authors, Jonathan S Draper.
Oncotarget, 2015 Mar 10; 6(9). PMID: 25749523    Free PMC article.
Transcriptome-wide identification and study of cancer-specific splicing events across multiple tumors.
Yihsuan S Tsai, Daniel Dominguez, Shawn M Gomez, Zefeng Wang.
Oncotarget, 2015 Mar 10; 6(9). PMID: 25749525    Free PMC article.
Machine learning applications in cancer prognosis and prediction.
Konstantina Kourou, Themis P Exarchos, +2 authors, Dimitrios I Fotiadis.
Comput Struct Biotechnol J, 2015 Mar 10; 13. PMID: 25750696    Free PMC article.
Highly Cited. Review.
Network-based approach to identify prognostic biomarkers for estrogen receptor-positive breast cancer treatment with tamoxifen.
Rong Liu, Cheng-Xian Guo, Hong-Hao Zhou.
Cancer Biol Ther, 2015 Mar 11; 16(2). PMID: 25756514    Free PMC article.
Pseudogenes transcribed in breast invasive carcinoma show subtype-specific expression and ceRNA potential.
Joshua D Welch, Jeanette Baran-Gale, +2 authors, Jan F Prins.
BMC Genomics, 2015 Mar 15; 16. PMID: 25765044    Free PMC article.
Can molecular subtyping replace axillary nodal status as prognostic marker in breast cancer?
Debarshi Jana, Diptendra Kumar Sarkar, +3 authors, Syamsundar Mandal.
Indian J Surg Oncol, 2015 Mar 15; 5(4). PMID: 25767340    Free PMC article.
ZNF32 inhibits autophagy through the mTOR pathway and protects MCF-7 cells from stimulus-induced cell death.
Yanyan Li, Le Zhang, +9 authors, Yuquan Wei.
Sci Rep, 2015 Mar 20; 5. PMID: 25786368    Free PMC article.
Molecular portrait of breast cancer in China reveals comprehensive transcriptomic likeness to Caucasian breast cancer and low prevalence of luminal A subtype.
Xiaoyan Huang, Matteo Dugo, +13 authors, Rosaria Orlandi.
Cancer Med, 2015 Mar 20; 4(7). PMID: 25787708    Free PMC article.
Test set bias affects reproducibility of gene signatures.
Prasad Patil, Pierre-Olivier Bachant-Winner, Benjamin Haibe-Kains, Jeffrey T Leek.
Bioinformatics, 2015 Mar 20; 31(14). PMID: 25788628    Free PMC article.
Intra-tumour signalling entropy determines clinical outcome in breast and lung cancer.
Christopher R S Banerji, Simone Severini, Carlos Caldas, Andrew E Teschendorff.
PLoS Comput Biol, 2015 Mar 21; 11(3). PMID: 25793737    Free PMC article.
Cell signaling events differentiate ER-negative subtypes from ER-positive breast cancer.
Maria J Worsham, Dhanajay Chitale, +2 authors, George Divine.
Med Oncol, 2015 Mar 26; 32(5). PMID: 25805566
Race, response to chemotherapy, and outcome within clinical breast cancer subtypes.
J R Tichy, A M Deal, +2 authors, L A Carey.
Breast Cancer Res Treat, 2015 Mar 31; 150(3). PMID: 25814053    Free PMC article.
The Rab2A GTPase promotes breast cancer stem cells and tumorigenesis via Erk signaling activation.
Man-Li Luo, Chang Gong, +10 authors, Kun Ping Lu.
Cell Rep, 2015 Mar 31; 11(1). PMID: 25818297    Free PMC article.
Head and neck cancer subtypes with biological and clinical relevance: Meta-analysis of gene-expression data.
Loris De Cecco, Monica Nicolau, +5 authors, Silvana Canevari.
Oncotarget, 2015 Mar 31; 6(11). PMID: 25821127    Free PMC article.
Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated with Estrogen Receptor-Negative Subtypes and Poor Prognosis.
Hao Tang, Salwa Sebti, +8 authors, Beth Levine.
EBioMedicine, 2015 Apr 01; 2(3). PMID: 25825707    Free PMC article.
[Molecular pathology for breast cancer: Importance of the gene expression profile].
C Denkert, B M Pfitzner, B I Heppner, M Dietel.
Pathologe, 2015 Apr 04; 36(2). PMID: 25836324
Review.
Transgelin: a potentially useful diagnostic marker differentially expressed in triple-negative and non-triple-negative breast cancers.
Deepthi Rao, Bruce F Kimler, +3 authors, Ossama Tawfik.
Hum Pathol, 2015 Apr 07; 46(6). PMID: 25841305    Free PMC article.
Use of formalin-fixed paraffin-embedded samples for gene expression studies in breast cancer patients.
Valeria Musella, Maurizio Callari, +8 authors, Vera Cappelletti.
PLoS One, 2015 Apr 07; 10(4). PMID: 25844937    Free PMC article.
Phase II Study of Gemcitabine, Carboplatin, and Iniparib As Neoadjuvant Therapy for Triple-Negative and BRCA1/2 Mutation-Associated Breast Cancer With Assessment of a Tumor-Based Measure of Genomic Instability: PrECOG 0105.
Melinda L Telli, Kristin C Jensen, +18 authors, James M Ford.
J Clin Oncol, 2015 Apr 08; 33(17). PMID: 25847929    Free PMC article.
Highly Cited.
TBCRC009: A Multicenter Phase II Clinical Trial of Platinum Monotherapy With Biomarker Assessment in Metastatic Triple-Negative Breast Cancer.
Steven J Isakoff, Erica L Mayer, +16 authors, Leif W Ellisen.
J Clin Oncol, 2015 Apr 08; 33(17). PMID: 25847936    Free PMC article.
Highly Cited.
Prognostic stromal gene signatures in breast cancer.
Sofia Winslow, Karin Leandersson, Anders Edsjö, Christer Larsson.
Breast Cancer Res, 2015 Apr 08; 17. PMID: 25848820    Free PMC article.
Markers for the identification of late breast cancer recurrence.
Ivana Sestak, Jack Cuzick.
Breast Cancer Res, 2015 Apr 08; 17. PMID: 25848913    Free PMC article.
Review.
Molecular subtyping for clinically defined breast cancer subgroups.
Xi Zhao, Einar Andreas Rødland, Robert Tibshirani, Sylvia Plevritis.
Breast Cancer Res, 2015 Apr 08; 17. PMID: 25849221    Free PMC article.
Mouse mammary stem cells express prognostic markers for triple-negative breast cancer.
Kelly J Soady, Howard Kendrick, +8 authors, Matthew J Smalley.
Breast Cancer Res, 2015 Apr 08; 17. PMID: 25849541    Free PMC article.
Patient-derived xenograft models of breast cancer and their predictive power.
James R Whittle, Michael T Lewis, Geoffrey J Lindeman, Jane E Visvader.
Breast Cancer Res, 2015 Apr 08; 17. PMID: 25849559    Free PMC article.
Highly Cited. Review.
Integrated analysis reveals microRNA networks coordinately expressed with key proteins in breast cancer.
Miriam Ragle Aure, Sandra Jernström, +12 authors, Vessela N Kristensen.
Genome Med, 2015 Apr 16; 7(1). PMID: 25873999    Free PMC article.
AGR3 in breast cancer: prognostic impact and suitable serum-based biomarker for early cancer detection.
Stefan Garczyk, Saskia von Stillfried, +9 authors, Edgar Dahl.
PLoS One, 2015 Apr 16; 10(4). PMID: 25875093    Free PMC article.
PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer.
Ana Bosch, Zhiqiang Li, +25 authors, José Baselga.
Sci Transl Med, 2015 Apr 17; 7(283). PMID: 25877889    Free PMC article.
Highly Cited.
Integrative analysis of survival-associated gene sets in breast cancer.
Frederick S Varn, Matthew H Ung, Shao Ke Lou, Chao Cheng.
BMC Med Genomics, 2015 Apr 17; 8. PMID: 25881247    Free PMC article.
Therapies for triple negative breast cancer.
Eleni Andreopoulou, Sarah J Schweber, Joseph A Sparano, Hayley M McDaid.
Expert Opin Pharmacother, 2015 Apr 18; 16(7). PMID: 25881743    Free PMC article.
Review.
Tumor expression, plasma levels and genetic polymorphisms of the coagulation inhibitor TFPI are associated with clinicopathological parameters and survival in breast cancer, in contrast to the coagulation initiator TF.
Mari Tinholt, Hans Kristian Moen Vollan, +9 authors, Nina Iversen.
Breast Cancer Res, 2015 Apr 18; 17. PMID: 25882602    Free PMC article.
BRCA1 Alternative splicing landscape in breast tissue samples.
Atocha Romero, Francisco García-García, +9 authors, Miguel de la Hoya.
BMC Cancer, 2015 Apr 18; 15. PMID: 25884417    Free PMC article.
Association of high obesity with PAM50 breast cancer intrinsic subtypes and gene expression.
Marilyn L Kwan, Candyce H Kroenke, +10 authors, Bette J Caan.
BMC Cancer, 2015 Apr 18; 15. PMID: 25884832    Free PMC article.
Evaluation of public cancer datasets and signatures identifies TP53 mutant signatures with robust prognostic and predictive value.
Brian David Lehmann, Yan Ding, +6 authors, Yajun Yi.
BMC Cancer, 2015 Apr 18; 15. PMID: 25886164    Free PMC article.
Gene-expression molecular subtyping of triple-negative breast cancer tumours: importance of immune response.
Pascal Jézéquel, Delphine Loussouarn, +8 authors, Mario Campone.
Breast Cancer Res, 2015 Apr 19; 17. PMID: 25887482    Free PMC article.
Highly Cited.
Long non-coding RNA expression profiles predict metastasis in lymph node-negative breast cancer independently of traditional prognostic markers.
Kristina P Sørensen, Mads Thomassen, +5 authors, Torben A Kruse.
Breast Cancer Res, 2015 Apr 19; 17. PMID: 25887545    Free PMC article.
Quantification of HER family receptors in breast cancer.
Paolo Nuciforo, Nina Radosevic-Robin, Tony Ng, Maurizio Scaltriti.
Breast Cancer Res, 2015 Apr 19; 17. PMID: 25887735    Free PMC article.
Review.
Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression.
Floriana Centritto, Gabriela Paroni, +16 authors, Enrico Garattini.
EMBO Mol Med, 2015 Apr 19; 7(7). PMID: 25888236    Free PMC article.
HER2 and uPAR cooperativity contribute to metastatic phenotype of HER2-positive breast cancer.
Vineesh Indira Chandran, Serenella Eppenberger-Castori, +2 authors, Marie Ranson.
Oncoscience, 2015 Apr 22; 2(3). PMID: 25897424    Free PMC article.
Review.
Molecular characterization and targeted therapeutic approaches in breast cancer.
Angela Toss, Massimo Cristofanilli.
Breast Cancer Res, 2015 Apr 24; 17. PMID: 25902832    Free PMC article.
Review.
Defining breast cancer intrinsic subtypes by quantitative receptor expression.
Maggie C U Cheang, Miguel Martin, +21 authors, Lisa A Carey.
Oncologist, 2015 Apr 25; 20(5). PMID: 25908555    Free PMC article.
Genome-wide analysis of alternative transcripts in human breast cancer.
Ji Wen, Kevin H Toomer, Zhibin Chen, Xiaodong Cai.
Breast Cancer Res Treat, 2015 Apr 29; 151(2). PMID: 25913416    Free PMC article.
Breastfeeding, PAM50 tumor subtype, and breast cancer prognosis and survival.
Marilyn L Kwan, Philip S Bernard, +12 authors, Bette J Caan.
J Natl Cancer Inst, 2015 Apr 30; 107(7). PMID: 25921910    Free PMC article.
Organ-specific adaptive signaling pathway activation in metastatic breast cancer cells.
Riesa M Burnett, Kelly E Craven, +6 authors, Harikrishna Nakshatri.
Oncotarget, 2015 May 01; 6(14). PMID: 25926557    Free PMC article.
A phase II clinical trial of weekly paclitaxel and carboplatin in combination with panitumumab in metastatic triple negative breast cancer.
S Cowherd, L D Miller, +5 authors, J A Lawrence.
Cancer Biol Ther, 2015 May 01; 16(5). PMID: 25928118    Free PMC article.
Identification of sample-specific regulations using integrative network level analysis.
Chengyu Liu, Riku Louhimo, +2 authors, Sampsa Hautaniemi.
BMC Cancer, 2015 May 01; 15. PMID: 25928379    Free PMC article.
Developing a new generation of breast cancer clinical gene expression tests.
Zuzana Kos, Torsten O Nielsen.
Breast Cancer Res, 2014 Jan 01; 16(4). PMID: 25928431    Free PMC article.
PDL1 expression in inflammatory breast cancer is frequent and predicts for the pathological response to chemotherapy.
François Bertucci, Pascal Finetti, +6 authors, Steven van Laere.
Oncotarget, 2015 May 06; 6(15). PMID: 25940795    Free PMC article.
Coordinated epigenetic remodelling of transcriptional networks occurs during early breast carcinogenesis.
Warwick J Locke, Elena Zotenko, +6 authors, Susan J Clark.
Clin Epigenetics, 2015 May 12; 7. PMID: 25960784    Free PMC article.
Notch promotes recurrence of dormant tumor cells following HER2/neu-targeted therapy.
Daniel L Abravanel, George K Belka, +4 authors, Lewis A Chodosh.
J Clin Invest, 2015 May 12; 125(6). PMID: 25961456    Free PMC article.
Matrix metalloproteinases as breast cancer drivers and therapeutic targets.
Evette S Radisky, Derek C Radisky.
Front Biosci (Landmark Ed), 2015 May 12; 20. PMID: 25961550    Free PMC article.
Review.
Pathway-based personalized analysis of breast cancer expression data.
Anna Livshits, Anna Git, +2 authors, Eytan Domany.
Mol Oncol, 2015 May 13; 9(7). PMID: 25963740    Free PMC article.
Decreased expression of SOX17 is associated with tumor progression and poor prognosis in breast cancer.
De-Yuan Fu, Hao-Sheng Tan, +6 authors, Chuan-Li Ren.
Tumour Biol, 2015 May 15; 36(10). PMID: 25971583
ISOpureR: an R implementation of a computational purification algorithm of mixed tumour profiles.
Catalina V Anghel, Gerald Quon, +4 authors, Paul C Boutros.
BMC Bioinformatics, 2015 May 15; 16. PMID: 25972088    Free PMC article.
Identification and evaluation of network modules for the prognosis of basal-like breast cancer.
Robin M Hallett, Jessica G Cockburn, +3 authors, Anita Bane.
Oncotarget, 2015 May 21; 6(19). PMID: 25991675    Free PMC article.
From bench to bedside: What do we know about hormone receptor-positive and human epidermal growth factor receptor 2-positive breast cancer?
Victoria Shang Wu, Noriko Kanaya, +2 authors, Shiuan Chen.
J Steroid Biochem Mol Biol, 2015 May 23; 153. PMID: 25998416    Free PMC article.
Review.
Gene expression in "young adult type" breast cancer: a retrospective analysis.
Rebecca H Johnson, Pingzhao Hu, Cheng Fan, Carey K Anders.
Oncotarget, 2015 May 23; 6(15). PMID: 25999348    Free PMC article.
Molecular characterization of patients with pathologic complete response or early failure after neoadjuvant chemotherapy for locally advanced breast cancer using next generation sequencing and nCounter assay.
Kyunghee Park, Moon Ki Choi, +11 authors, Yeon Hee Park.
Oncotarget, 2015 May 27; 6(27). PMID: 26009992    Free PMC article.
Serial expression analysis of breast tumors during neoadjuvant chemotherapy reveals changes in cell cycle and immune pathways associated with recurrence and response.
Mark Jesus M Magbanua, Denise M Wolf, +10 authors, Laura J van 't Veer.
Breast Cancer Res, 2015 May 30; 17. PMID: 26021444    Free PMC article.
Diagnosis of Basal-Like Breast Cancer Using a FOXC1-Based Assay.
Tor W Jensen, Tania Ray, +9 authors, Partha S Ray.
J Natl Cancer Inst, 2015 Jun 05; 107(8). PMID: 26041837    Free PMC article.
miR-30e* is an independent subtype-specific prognostic marker in breast cancer.
F D'Aiuto, M Callari, +6 authors, M G Daidone.
Br J Cancer, 2015 Jun 10; 113(2). PMID: 26057454    Free PMC article.
Tumor tissue microRNA expression in association with triple-negative breast cancer outcomes.
Yan Liu, Qiuyin Cai, +8 authors, Xiao-Ou Shu.
Breast Cancer Res Treat, 2015 Jun 13; 152(1). PMID: 26062749    Free PMC article.
Association of Protein Translation and Extracellular Matrix Gene Sets with Breast Cancer Metastasis: Findings Uncovered on Analysis of Multiple Publicly Available Datasets Using Individual Patient Data Approach.
Nilotpal Chowdhury, Shantanu Sapru.
PLoS One, 2015 Jun 17; 10(6). PMID: 26080057    Free PMC article.
Anti-CSF-1 treatment is effective to prevent carcinoma invasion induced by monocyte-derived cells but scarcely by microglia.
Eva Rietkötter, Annalen Bleckmann, +8 authors, Tobias Pukrop.
Oncotarget, 2015 Jun 23; 6(17). PMID: 26098772    Free PMC article.
Race-associated biological differences among Luminal A breast tumors.
Monica D'Arcy, Jodie Fleming, +3 authors, Melissa A Troester.
Breast Cancer Res Treat, 2015 Jun 26; 152(2). PMID: 26109344    Free PMC article.
Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer.
Grace O Silva, Xiaping He, +8 authors, Charles M Perou.
Breast Cancer Res Treat, 2015 Jun 26; 152(2). PMID: 26109346    Free PMC article.
Widespread intron retention diversifies most cancer transcriptomes.
Heidi Dvinge, Robert K Bradley.
Genome Med, 2015 Jun 27; 7(1). PMID: 26113877    Free PMC article.
Highly Cited.
The Effect of Molecular Subtype and Residual Disease on Locoregional Recurrence in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy and Postmastectomy Radiation.
T Jonathan Yang, Monica Morrow, +6 authors, Alice Y Ho.
Ann Surg Oncol, 2015 Jul 02; 22 Suppl 3. PMID: 26130454    Free PMC article.
The Discovery of Novel Biomarkers Improves Breast Cancer Intrinsic Subtype Prediction and Reconciles the Labels in the METABRIC Data Set.
Heloisa Helena Milioli, Renato Vimieiro, +3 authors, Pablo Moscato.
PLoS One, 2015 Jul 02; 10(7). PMID: 26132585    Free PMC article.
Evaluation of the pathological response and prognosis following neoadjuvant chemotherapy in molecular subtypes of breast cancer.
Yue Zhao, Xiaoqiu Dong, +4 authors, Dongwei Zhang.
Onco Targets Ther, 2015 Jul 08; 8. PMID: 26150728    Free PMC article.
Progesterone receptor modulates ERα action in breast cancer.
Hisham Mohammed, I Alasdair Russell, +22 authors, Jason S Carroll.
Nature, 2015 Jul 15; 523(7560). PMID: 26153859    Free PMC article.
Highly Cited.
TGFβ-Mediated induction of SphK1 as a potential determinant in human MDA-MB-231 breast cancer cell bone metastasis.
Keith R Stayrook, Justin K Mack, +7 authors, Theresa A Guise.
Bonekey Rep, 2015 Jul 15; 4. PMID: 26157579    Free PMC article.
The Clinicopathologic and Prognostic Value of Altered Chromosome 17 Centromere Copy Number in HER2 Fish Equivocal Breast Carcinomas.
Hongfei Ji, Qijia Xuan, +2 authors, Qingyuan Zhang.
PLoS One, 2015 Jul 15; 10(7). PMID: 26161550    Free PMC article.
Functional genomic mRNA profiling of a large cancer data base demonstrates mesothelin overexpression in a broad range of tumor types.
Laetitia E Lamberts, Derk Jan A de Groot, +2 authors, Rudolf S N Fehrmann.
Oncotarget, 2015 Jul 15; 6(29). PMID: 26172299    Free PMC article.
Reverse phase protein arrays in signaling pathways: a data integration perspective.
Chad J Creighton, Shixia Huang.
Drug Des Devel Ther, 2015 Jul 18; 9. PMID: 26185419    Free PMC article.
Review.
Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?
Wilbert Zwart, Huub Terra, Sabine C Linn, Sanne B Schagen.
Nat Rev Clin Oncol, 2015 Jul 22; 12(10). PMID: 26196252
Review.
Monitoring therapeutic efficacy of sunitinib using [(18)F]FDG and [(18)F]FMISO PET in an immunocompetent model of luminal B (HER2-positive)-type mammary carcinoma.
Benoît Thézé, Nicholas Bernards, +5 authors, Raphaël Boisgard.
BMC Cancer, 2015 Jul 23; 15. PMID: 26198000    Free PMC article.
Survival of patients with structurally-grouped TP53 mutations in ovarian and breast cancers.
Brandon-Luke L Seagle, Kevin H Eng, +3 authors, Shohreh Shahabi.
Oncotarget, 2015 Jul 29; 6(21). PMID: 26215675    Free PMC article.
Optimal approach in early breast cancer: Adjuvant and neoadjuvant treatment.
J Ribeiro, B Sousa, F Cardoso.
EJC Suppl, 2013 Sep 01; 11(2). PMID: 26217109    Free PMC article.
Review.
Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype.
Haiquan Lu, Debangshu Samanta, +5 authors, Gregg L Semenza.
Proc Natl Acad Sci U S A, 2015 Aug 01; 112(33). PMID: 26229077    Free PMC article.
Highly Cited.
Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics.
Andrew Goodspeed, Laura M Heiser, Joe W Gray, James C Costello.
Mol Cancer Res, 2015 Aug 08; 14(1). PMID: 26248648    Free PMC article.
Highly Cited. Review.
A Molecular Portrait of High-Grade Ductal Carcinoma In Situ.
Martin C Abba, Ting Gong, +10 authors, C Marcelo Aldaz.
Cancer Res, 2015 Aug 08; 75(18). PMID: 26249178    Free PMC article.
The molecular landscape of premenopausal breast cancer.
Serena Liao, Ryan J Hartmaier, +11 authors, Steffi Oesterreich.
Breast Cancer Res, 2015 Aug 08; 17. PMID: 26251034    Free PMC article.
Targeting BCL-2 to enhance vulnerability to therapy in estrogen receptor-positive breast cancer.
D Merino, S W Lok, J E Visvader, G J Lindeman.
Oncogene, 2015 Aug 11; 35(15). PMID: 26257067
Review.
A simplicial complex-based approach to unmixing tumor progression data.
Theodore Roman, Amir Nayyeri, Brittany Terese Fasy, Russell Schwartz.
BMC Bioinformatics, 2015 Aug 13; 16. PMID: 26264682    Free PMC article.
Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity.
Alexandra Van Keymeulen, May Yin Lee, +10 authors, Cédric Blanpain.
Nature, 2015 Aug 13; 525(7567). PMID: 26266985
Highly Cited.
Developmental Transcriptome for a Facultatively Eusocial Bee, Megalopta genalis.
Beryl M Jones, William T Wcislo, Gene E Robinson.
G3 (Bethesda), 2015 Aug 16; 5(10). PMID: 26276382    Free PMC article.
Progress in adjuvant chemotherapy for breast cancer: an overview.
Jesus Anampa, Della Makower, Joseph A Sparano.
BMC Med, 2015 Aug 19; 13. PMID: 26278220    Free PMC article.
Highly Cited. Review.
MVDA: a multi-view genomic data integration methodology.
Angela Serra, Michele Fratello, +3 authors, Dario Greco.
BMC Bioinformatics, 2015 Aug 19; 16. PMID: 26283178    Free PMC article.
Biological and Clinical Significance of MAD2L1 and BUB1, Genes Frequently Appearing in Expression Signatures for Breast Cancer Prognosis.
Zhanwei Wang, Dionyssios Katsaros, +7 authors, Herbert Yu.
PLoS One, 2015 Aug 20; 10(8). PMID: 26287798    Free PMC article.
Development and verification of the PAM50-based Prosigna breast cancer gene signature assay.
Brett Wallden, James Storhoff, +16 authors, Joel S Parker.
BMC Med Genomics, 2015 Aug 25; 8. PMID: 26297356    Free PMC article.
Highly Cited.
MEXPRESS: visualizing expression, DNA methylation and clinical TCGA data.
Alexander Koch, Tim De Meyer, Jana Jeschke, Wim Van Criekinge.
BMC Genomics, 2015 Aug 27; 16. PMID: 26306699    Free PMC article.
Highly Cited.
hERG1 Potassium Channels: Novel Biomarkers in Human Solid Cancers.
Elena Lastraioli, Tiziano Lottini, +2 authors, Annarosa Arcangeli.
Biomed Res Int, 2015 Sep 05; 2015. PMID: 26339650    Free PMC article.
Review.
Stratifying triple-negative breast cancer prognosis using 18F-FDG-PET/CT imaging.
Yong Yue, Xiaojiang Cui, +3 authors, Benedick Fraass.
Breast Cancer Res Treat, 2015 Sep 09; 153(3). PMID: 26346756    Free PMC article.
Screening of feature genes in distinguishing different types of breast cancer using support vector machine.
Qi Wang, Xudong Liu.
Onco Targets Ther, 2015 Sep 09; 8. PMID: 26347014    Free PMC article.
Pathological response rate in hormone-positive breast cancer patients treated with neoadjuvant FEC and triweekly docetaxel: a case series.
Takayoshi Kiba, Nao Morii, +4 authors, Hiroyasu Yamashiro.
Breast Cancer (Dove Med Press), 2015 Sep 12; 7. PMID: 26357489    Free PMC article.
Comparison of the Genomic Landscape Between Primary Breast Cancer in African American Versus White Women and the Association of Racial Differences With Tumor Recurrence.
Tanya Keenan, Beverly Moy, +6 authors, Aditya Bardia.
J Clin Oncol, 2015 Sep 16; 33(31). PMID: 26371147    Free PMC article.
Highly Cited.
Contrasting breast cancer molecular subtypes across serial tumor progression stages: biological and prognostic implications.
Siker Kimbung, Anikó Kovács, +10 authors, Ingrid Hedenfalk.
Oncotarget, 2015 Sep 17; 6(32). PMID: 26375671    Free PMC article.
Associations between sociodemographic and clinicopathological factors and breast cancer subtypes in a population-based study.
Adana A M Llanos, Sheenu Chandwani, +4 authors, Kitaw Demissie.
Cancer Causes Control, 2015 Sep 18; 26(12). PMID: 26376894    Free PMC article.
Necdin is a breast cancer metastasis suppressor that regulates the transcription of c-Myc.
Minnkyong Lee, Sarah M Beggs, +7 authors, Nigel P S Crawford.
Oncotarget, 2015 Sep 19; 6(31). PMID: 26384308    Free PMC article.
Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential.
Claudia Cava, Gloria Bertoli, Isabella Castiglioni.
BMC Syst Biol, 2015 Sep 24; 9. PMID: 26391647    Free PMC article.
Review.
Beyond the one-locus-one-miRNA paradigm: microRNA isoforms enable deeper insights into breast cancer heterogeneity.
Aristeidis G Telonis, Phillipe Loher, +2 authors, Isidore Rigoutsos.
Nucleic Acids Res, 2015 Sep 25; 43(19). PMID: 26400174    Free PMC article.
Highly Cited.
Molecular portraits revealing the heterogeneity of breast tumor subtypes defined using immunohistochemistry markers.
Xiaofeng Dai, Yang Li, Zhonghu Bai, Xu-Qing Tang.
Sci Rep, 2015 Sep 26; 5. PMID: 26404658    Free PMC article.
CDK7-dependent transcriptional addiction in triple-negative breast cancer.
Yubao Wang, Tinghu Zhang, +14 authors, Jean J Zhao.
Cell, 2015 Sep 26; 163(1). PMID: 26406377    Free PMC article.
Highly Cited.
Molecular essence and endocrine responsiveness of estrogen receptor-negative, progesterone receptor-positive, and HER2-negative breast cancer.
Ke-Da Yu, Yi-Zhou Jiang, Shuang Hao, Zhi-Ming Shao.
BMC Med, 2015 Oct 07; 13. PMID: 26437901    Free PMC article.
Tools for translational epigenetic studies involving formalin-fixed paraffin-embedded human tissue: applying the Infinium HumanMethyation450 Beadchip assay to large population-based studies.
Ee Ming Wong, JiHoon E Joo, +8 authors, Melissa C Southey.
BMC Res Notes, 2015 Oct 07; 8. PMID: 26438025    Free PMC article.
Highly informative marker sets consisting of genes with low individual degree of differential expression.
V V Galatenko, M Yu Shkurnikov, +5 authors, A G Tonevitsky.
Sci Rep, 2015 Oct 09; 5. PMID: 26446398    Free PMC article.
Comprehensive profiling of biological processes reveals two major prognostic subtypes in breast cancer.
Fei Chen, Sheng Gao, +7 authors, Hong Yin.
Tumour Biol, 2015 Oct 09; 37(3). PMID: 26446459
Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer.
Giovanni Ciriello, Michael L Gatza, +30 authors, Charles M Perou.
Cell, 2015 Oct 10; 163(2). PMID: 26451490    Free PMC article.
Highly Cited.
Personalised pathway analysis reveals association between DNA repair pathway dysregulation and chromosomal instability in sporadic breast cancer.
Chao Liu, Sriganesh Srihari, +5 authors, Kim-Anh Lê Cao.
Mol Oncol, 2015 Oct 13; 10(1). PMID: 26456802    Free PMC article.
Down-regulation of miR-129-5p via the Twist1-Snail feedback loop stimulates the epithelial-mesenchymal transition and is associated with poor prognosis in breast cancer.
Yue Yu, Ying Zhao, +4 authors, Xu-Chen Cao.
Oncotarget, 2015 Oct 16; 6(33). PMID: 26460733    Free PMC article.
ALDH1A1 mRNA expression in association with prognosis of triple-negative breast cancer.
Yan Liu, Michelle Baglia, +7 authors, Xiao Ou Shu.
Oncotarget, 2015 Oct 16; 6(38). PMID: 26462023    Free PMC article.
Impact of immunohistological subtypes on the long-term prognosis of patients with metastatic breast cancer.
Kokoro Kobayashi, Yoshinori Ito, +8 authors, Kiyohiko Hatake.
Surg Today, 2015 Oct 16; 46(7). PMID: 26467559
Genomic aberrations in young and elderly  breast cancer patients.
Hatem A Azim, Bastien Nguyen, +2 authors, Christos Sotiriou.
BMC Med, 2015 Oct 16; 13. PMID: 26467651    Free PMC article.
Genome and transcriptome delineation of two major oncogenic pathways governing invasive ductal breast cancer development.
Luay Aswad, Surya Pavan Yenamandra, +3 authors, Vladimir A Kuznetsov.
Oncotarget, 2015 Oct 17; 6(34). PMID: 26474389    Free PMC article.
Cancer classification in the genomic era: five contemporary problems.
Qingxuan Song, Sofia D Merajver, Jun Z Li.
Hum Genomics, 2015 Oct 21; 9. PMID: 26481255    Free PMC article.
Review.
CCL9 Induced by TGFβ Signaling in Myeloid Cells Enhances Tumor Cell Survival in the Premetastatic Organ.
Hangyi H Yan, Jian Jiang, +7 authors, Li Yang.
Cancer Res, 2015 Oct 21; 75(24). PMID: 26483204    Free PMC article.
SEOM clinical guidelines in early-stage breast cancer 2015.
J A Garcia-Saenz, B Bermejo, +7 authors, E Ciruelos.
Clin Transl Oncol, 2015 Oct 27; 17(12). PMID: 26497356    Free PMC article.
Correlation between conductivity and prognostic factors in invasive breast cancer using magnetic resonance electric properties tomography (MREPT).
Soo-Yeon Kim, Jaewook Shin, +4 authors, Jung Hyun Yoon.
Eur Radiol, 2015 Oct 27; 26(7). PMID: 26497503
The unique transcriptional response produced by concurrent estrogen and progesterone treatment in breast cancer cells results in upregulation of growth factor pathways and switching from a Luminal A to a Basal-like subtype.
Eleanor F Need, Luke A Selth, +8 authors, Grant Buchanan.
BMC Cancer, 2015 Oct 27; 15. PMID: 26498662    Free PMC article.
Identifying patients at high risk of breast cancer recurrence: strategies to improve patient outcomes.
Yehoda M Martei, Jennifer M Matro.
Breast Cancer (Dove Med Press), 2015 Oct 28; 7. PMID: 26504408    Free PMC article.
Review.
The Cancer Genome Atlas Clinical Explorer: a web and mobile interface for identifying clinical-genomic driver associations.
HoJoon Lee, Jennifer Palm, Susan M Grimes, Hanlee P Ji.
Genome Med, 2015 Oct 29; 7. PMID: 26507825    Free PMC article.
A Gene Regulatory Program in Human Breast Cancer.
Renhua Li, John Campos, Joji Iida.
Genetics, 2015 Oct 30; 201(4). PMID: 26510790    Free PMC article.
Mutational profiling of brain metastasis from breast cancer: matched pair analysis of targeted sequencing between brain metastasis and primary breast cancer.
Ji Yun Lee, Kyunghee Park, +18 authors, Yeon Hee Park.
Oncotarget, 2015 Nov 04; 6(41). PMID: 26527317    Free PMC article.
Molecular Heterogeneity and Response to Neoadjuvant Human Epidermal Growth Factor Receptor 2 Targeting in CALGB 40601, a Randomized Phase III Trial of Paclitaxel Plus Trastuzumab With or Without Lapatinib.
Lisa A Carey, Donald A Berry, +15 authors, Clifford A Hudis.
J Clin Oncol, 2015 Nov 04; 34(6). PMID: 26527775    Free PMC article.
Highly Cited.
Understanding drugs in breast cancer through drug sensitivity screening.
Katharina Uhr, Wendy J C Prager-van der Smissen, +6 authors, John W M Martens.
Springerplus, 2015 Nov 07; 4. PMID: 26543746    Free PMC article.
Promoter methylation of TRIM9 as a marker for detection of circulating tumor DNA in breast cancer patients.
Chieko Mishima, Naofumi Kagara, +7 authors, Shinzaburo Noguchi.
Springerplus, 2015 Nov 07; 4. PMID: 26543769    Free PMC article.
Expression of androgen receptor splice variants in clinical breast cancers.
Theresa E Hickey, Connie M Irvine, +15 authors, Luke A Selth.
Oncotarget, 2015 Nov 12; 6(42). PMID: 26554309    Free PMC article.
EpCAM based capture detects and recovers circulating tumor cells from all subtypes of breast cancer except claudin-low.
Alexander Ring, Neal Mineyev, +9 authors, Julie E Lang.
Oncotarget, 2015 Nov 12; 6(42). PMID: 26556851    Free PMC article.
LINC00472 expression is regulated by promoter methylation and associated with disease-free survival in patients with grade 2 breast cancer.
Yi Shen, Zhanwei Wang, +6 authors, Herbert Yu.
Breast Cancer Res Treat, 2015 Nov 14; 154(3). PMID: 26564482    Free PMC article.
Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients.
Sara M Tolaney, Yves Boucher, +15 authors, Rakesh K Jain.
Proc Natl Acad Sci U S A, 2015 Nov 19; 112(46). PMID: 26578779    Free PMC article.
Highly Cited.
Differential expression of miRNAs in pancreatobiliary type of periampullary adenocarcinoma and its associated stroma.
V Sandhu, I M Bowitz Lothe, +11 authors, E H Kure.
Mol Oncol, 2015 Nov 22; 10(2). PMID: 26590090    Free PMC article.
Using second harmonic generation to predict patient outcome in solid tumors.
K Burke, M Smid, +6 authors, E Brown.
BMC Cancer, 2015 Nov 26; 15. PMID: 26603532    Free PMC article.
Breast cancer subtype as a predictor for outcomes and control in the setting of brain metastases treated with stereotactic radiosurgery.
Christopher S Grubb, Ashish Jani, +15 authors, Tony J C Wang.
J Neurooncol, 2015 Nov 30; 127(1). PMID: 26615564
Multiscale Embedded Gene Co-expression Network Analysis.
Won-Min Song, Bin Zhang.
PLoS Comput Biol, 2015 Dec 01; 11(11). PMID: 26618778    Free PMC article.
An Analysis of the Sensitivity of Proteogenomic Mapping of Somatic Mutations and Novel Splicing Events in Cancer.
Kelly V Ruggles, Zuojian Tang, +35 authors, David Fenyő.
Mol Cell Proteomics, 2015 Dec 04; 15(3). PMID: 26631509    Free PMC article.
MiRNAs and Other Epigenetic Changes as Biomarkers in Triple Negative Breast Cancer.
Andrea Mathe, Rodney J Scott, Kelly A Avery-Kiejda.
Int J Mol Sci, 2015 Dec 04; 16(12). PMID: 26633365    Free PMC article.
Review.
Systematic pan-cancer analysis of tumour purity.
Dvir Aran, Marina Sirota, Atul J Butte.
Nat Commun, 2015 Dec 05; 6. PMID: 26634437    Free PMC article.
Highly Cited.
Biomarkers in Breast Cancer - An Update.
M Schmidt, P A Fasching, M W Beckmann, H Kölbl.
Geburtshilfe Frauenheilkd, 2012 Sep 01; 72(9). PMID: 26640290    Free PMC article.
High Expression of Three-Gene Signature Improves Prediction of Relapse-Free Survival in Estrogen Receptor-Positive and Node-Positive Breast Tumors.
Arvind Thakkar, Hemanth Raj, +3 authors, Muralidhara Padigaru.
Biomark Insights, 2015 Dec 10; 10. PMID: 26648682    Free PMC article.
Intrinsic subtypes and genomic signatures of primary breast cancer and prognosis after systemic relapse.
Claudette Falato, Nicholas P Tobin, +3 authors, Theodoros Foukakis.
Mol Oncol, 2015 Dec 15; 10(4). PMID: 26651914    Free PMC article.
Reproducibility of Differential Proteomic Technologies in CPTAC Fractionated Xenografts.
David L Tabb, Xia Wang, +32 authors, Daniel C Liebler.
J Proteome Res, 2015 Dec 15; 15(3). PMID: 26653538    Free PMC article.
TP53 Mutational Analysis Enhances the Prognostic Accuracy of IHC4 and PAM50 Assays.
Ching-Hung Lin, I-Chiun Chen, +11 authors, Ann-Lii Cheng.
Sci Rep, 2015 Dec 17; 5. PMID: 26671300    Free PMC article.
Differential expression of neurogenes among breast cancer subtypes identifies high risk patients.
Patricia Fernández-Nogueira, Paloma Bragado, +5 authors, Pedro Gascón.
Oncotarget, 2015 Dec 18; 7(5). PMID: 26673618    Free PMC article.
Therapeutic targeting of casein kinase 1δ in breast cancer.
Laura H Rosenberg, Marie Lafitte, +10 authors, Derek R Duckett.
Sci Transl Med, 2015 Dec 18; 7(318). PMID: 26676609    Free PMC article.
Prognostic significance of FAM83D gene expression across human cancer types.
Peter J Walian, Bo Hang, Jian-Hua Mao.
Oncotarget, 2015 Dec 19; 7(3). PMID: 26678035    Free PMC article.
Expression of PAM50 Genes in Lung Cancer: Evidence that Interactions between Hormone Receptors and HER2/HER3 Contribute to Poor Outcome.
Jill M Siegfried, Yan Lin, +7 authors, Laura P Stabile.
Neoplasia, 2015 Dec 19; 17(11). PMID: 26678909    Free PMC article.
Reproductive risk factors in relation to molecular subtypes of breast cancer: Results from the nurses' health studies.
Julia S Sisti, Laura C Collins, +3 authors, A Heather Eliassen.
Int J Cancer, 2015 Dec 20; 138(10). PMID: 26684063    Free PMC article.
Response and survival of breast cancer intrinsic subtypes following multi-agent neoadjuvant chemotherapy.
Aleix Prat, Cheng Fan, +11 authors, Charles M Perou.
BMC Med, 2015 Dec 20; 13. PMID: 26684470    Free PMC article.
Breast cancer intrinsic subtype classification, clinical use and future trends.
Xiaofeng Dai, Ting Li, +4 authors, Bozhi Shi.
Am J Cancer Res, 2015 Dec 23; 5(10). PMID: 26693050    Free PMC article.
Highly Cited. Review.
TGFβ isoforms and receptors mRNA expression in breast tumours: prognostic value and clinical implications.
Chenfeng Chen, Kong-Nan Zhao, +4 authors, Luis Vitetta.
BMC Cancer, 2015 Dec 26; 15. PMID: 26703884    Free PMC article.
FOXA1 expression affects the proliferation activity of luminal breast cancer stem cell populations.
Kana Tachi, Akira Shiraishi, +5 authors, Osamu Ohneda.
Cancer Sci, 2015 Dec 29; 107(3). PMID: 26708273    Free PMC article.
Performance of Three-Biomarker Immunohistochemistry for Intrinsic Breast Cancer Subtyping in the AMBER Consortium.
Emma H Allott, Stephanie M Cohen, +19 authors, Melissa A Troester.
Cancer Epidemiol Biomarkers Prev, 2015 Dec 30; 25(3). PMID: 26711328    Free PMC article.
Heat shock protein 27 and gross cystic disease fluid protein 15 play critical roles in molecular apocrine breast cancer.
Xiaozhen Liu, Changyun Feng, +5 authors, Yun Niu.
Tumour Biol, 2015 Dec 30; 37(6). PMID: 26711786
Proteomic maps of breast cancer subtypes.
Stefka Tyanova, Reidar Albrechtsen, +3 authors, Tamar Geiger.
Nat Commun, 2016 Jan 05; 7. PMID: 26725330    Free PMC article.
Highly Cited.
Integrative analysis of breast cancer reveals prognostic haematopoietic activity and patient-specific immune response profiles.
Frederick S Varn, Erik H Andrews, David W Mullins, Chao Cheng.
Nat Commun, 2016 Jan 05; 7. PMID: 26725977    Free PMC article.
Subtype-specific accumulation of intracellular zinc pools is associated with the malignant phenotype in breast cancer.
Paige Chandler, Bose S Kochupurakkal, +3 authors, Shannon L Kelleher.
Mol Cancer, 2016 Jan 06; 15. PMID: 26728511    Free PMC article.
ELF5 isoform expression is tissue-specific and significantly altered in cancer.
Catherine L Piggin, Daniel L Roden, +3 authors, Christopher J Ormandy.
Breast Cancer Res, 2016 Jan 08; 18(1). PMID: 26738740    Free PMC article.
Developmental Insights into Breast Cancer Intratumoral Heterogeneity.
Mei Zhang, Jeffrey M Rosen.
Trends Cancer, 2016 Jan 12; 1(4). PMID: 26753176    Free PMC article.
Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer.
Tania M Puvirajesinghe, François Bertucci, +19 authors, Jean-Paul Borg.
Nat Commun, 2016 Jan 13; 7. PMID: 26754771    Free PMC article.
Statistical Significance of Clustering using Soft Thresholding.
Hanwen Huang, Yufeng Liu, Ming Yuan, J S Marron.
J Comput Graph Stat, 2016 Jan 13; 24(4). PMID: 26755893    Free PMC article.
AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation.
Chia-Wei Li, Weiya Xia, +23 authors, Mien-Chie Hung.
Cancer Res, 2016 Jan 14; 76(6). PMID: 26759241    Free PMC article.
Iteratively refining breast cancer intrinsic subtypes in the METABRIC dataset.
Heloisa H Milioli, Renato Vimieiro, +3 authors, Pablo Moscato.
BioData Min, 2016 Jan 16; 9. PMID: 26770261    Free PMC article.
Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance.
Richard Marcotte, Azin Sayad, +10 authors, Benjamin G Neel.
Cell, 2016 Jan 16; 164(1-2). PMID: 26771497    Free PMC article.
Highly Cited.
A Network-Based Model of Oncogenic Collaboration for Prediction of Drug Sensitivity.
Ted G Laderas, Laura M Heiser, Kemal Sönmez.
Front Genet, 2016 Jan 19; 6. PMID: 26779250    Free PMC article.
Prognostic Significance of Promoter DNA Hypermethylation of cysteine dioxygenase 1 (CDO1) Gene in Primary Breast Cancer.
Naoko Minatani, Mina Waraya, +11 authors, Masahiko Watanabe.
PLoS One, 2016 Jan 20; 11(1). PMID: 26785325    Free PMC article.
p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer.
Emily Powell, Jiansu Shao, +11 authors, Helen Piwnica-Worms.
Breast Cancer Res, 2016 Jan 29; 18(1). PMID: 26818199    Free PMC article.
Changes in intrinsic subtype of breast cancer during tumor progression in the same patient.
Chungyeul Kim, Jungjoo Lee, Wonyoung Lee, Aeree Kim.
Int J Clin Exp Pathol, 2016 Jan 30; 8(11). PMID: 26823864    Free PMC article.
Breast Cancer-Associated Fibroblasts: Where We Are and Where We Need to Go.
Rachel J Buchsbaum, Sun Young Oh.
Cancers (Basel), 2016 Feb 02; 8(2). PMID: 26828520    Free PMC article.
Highly Cited. Review.
Study design requirements for RNA sequencing-based breast cancer diagnostics.
Arvind Singh Mer, Daniel Klevebring, Henrik Grönberg, Mattias Rantalainen.
Sci Rep, 2016 Feb 03; 6. PMID: 26830453    Free PMC article.
Transcriptional Profiles from Paired Normal Samples Offer Complementary Information on Cancer Patient Survival--Evidence from TCGA Pan-Cancer Data.
Xiu Huang, David F Stern, Hongyu Zhao.
Sci Rep, 2016 Feb 04; 6. PMID: 26837275    Free PMC article.
Immune Signatures Following Single Dose Trastuzumab Predict Pathologic Response to PreoperativeTrastuzumab and Chemotherapy in HER2-Positive Early Breast Cancer.
Vinay Varadan, Hannah Gilmore, +11 authors, Lyndsay N Harris.
Clin Cancer Res, 2016 Feb 05; 22(13). PMID: 26842237    Free PMC article.
Targeted therapies with companion diagnostics in the management of breast cancer: current perspectives.
Meagan B Myers.
Pharmgenomics Pers Med, 2016 Feb 10; 9. PMID: 26858530    Free PMC article.
Review.
Bayesian inference for latent biologic structure with determinantal point processes (DPP).
Yanxun Xu, Peter Müller, Donatello Telesca.
Biometrics, 2016 Feb 14; 72(3). PMID: 26873271    Free PMC article.
Patterns in target-directed breast cancer research.
Sofia Torres, Christine Simmons, +3 authors, Maureen Trudeau.
Springerplus, 2016 Feb 16; 5. PMID: 26877907    Free PMC article.
An unsupervised MVA method to compare specific regions in human breast tumor tissue samples using ToF-SIMS.
Blake M Bluestein, Fionnuala Morrish, +4 authors, Lara J Gamble.
Analyst, 2016 Feb 16; 141(6). PMID: 26878076    Free PMC article.
Identification of differentially expressed miRNAs in individual breast cancer patient and application in personalized medicine.
F Peng, Y Zhang, +9 authors, Y Gu.
Oncogenesis, 2016 Feb 16; 5. PMID: 26878388    Free PMC article.
Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis.
Rachael Natrajan, Heba Sailem, +5 authors, Yinyin Yuan.
PLoS Med, 2016 Feb 18; 13(2). PMID: 26881778    Free PMC article.
The SOX11 transcription factor is a critical regulator of basal-like breast cancer growth, invasion, and basal-like gene expression.
Jonathan H Shepherd, Ivan P Uray, +4 authors, Powel H Brown.
Oncotarget, 2016 Feb 20; 7(11). PMID: 26894864    Free PMC article.
Changing molecular profile of brain metastases compared with matched breast primary cancers and impact on clinical outcomes.
A H Thomson, J McGrane, +4 authors, R Jenkins.
Br J Cancer, 2016 Feb 26; 114(7). PMID: 26908328    Free PMC article.
Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer.
Wendy M Swetzig, Jianmin Wang, Gokul M Das.
Oncotarget, 2016 Feb 26; 7(13). PMID: 26909605    Free PMC article.
Prognostic ability of EndoPredict compared to research-based versions of the PAM50 risk of recurrence (ROR) scores in node-positive, estrogen receptor-positive, and HER2-negative breast cancer. A GEICAM/9906 sub-study.
Miguel Martin, Jan C Brase, +15 authors, Alvaro Rodriguez-Lescure.
Breast Cancer Res Treat, 2016 Feb 26; 156(1). PMID: 26909792    Free PMC article.
The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repair.
C Bassi, Y-T Li, +8 authors, C Gorrini.
Cell Death Differ, 2016 Feb 27; 23(7). PMID: 26915295    Free PMC article.
Digital image analysis outperforms manual biomarker assessment in breast cancer.
Gustav Stålhammar, Nelson Fuentes Martinez, +9 authors, Johan Hartman.
Mod Pathol, 2016 Feb 27; 29(4). PMID: 26916072
Metformin attenuates transforming growth factor beta (TGF-β) mediated oncogenesis in mesenchymal stem-like/claudin-low triple negative breast cancer.
Reema Wahdan-Alaswad, J Chuck Harrell, +3 authors, Ann D Thor.
Cell Cycle, 2016 Feb 27; 15(8). PMID: 26919310    Free PMC article.
Galectin signatures contribute to the heterogeneity of breast cancer and provide new prognostic information and therapeutic targets.
Andrée-Anne Grosset, Marilyne Labrie, +3 authors, Yves St-Pierre.
Oncotarget, 2016 Mar 05; 7(14). PMID: 26933916    Free PMC article.
Gene modules associated with breast cancer distant metastasis-free survival in the PAM50 molecular subtypes.
Rong Liu, Wei Zhang, Zhao-Qian Liu, Hong-Hao Zhou.
Oncotarget, 2016 Mar 05; 7(16). PMID: 26934123    Free PMC article.
Neoadjuvant therapy for early-stage breast cancer: the clinical utility of pertuzumab.
Jahnavi Gollamudi, Jenny G Parvani, William P Schiemann, Shaveta Vinayak.
Cancer Manag Res, 2016 Mar 05; 8. PMID: 26937204    Free PMC article.
Review.
Identification of mRNA isoform switching in breast cancer.
Wei Zhao, Katherine A Hoadley, Joel S Parker, Charles M Perou.
BMC Genomics, 2016 Mar 05; 17. PMID: 26939613    Free PMC article.
Biological network-driven gene selection identifies a stromal immune module as a key determinant of triple-negative breast carcinoma prognosis.
H Bonsang-Kitzis, B Sadacca, +4 authors, F Reyal.
Oncoimmunology, 2016 Mar 05; 5(1). PMID: 26942074    Free PMC article.
A combination of trastuzumab and BAG-1 inhibition synergistically targets HER2 positive breast cancer cells.
Emmanouil Papadakis, Natalia Robson, +10 authors, Ramsey Cutress.
Oncotarget, 2016 Mar 10; 7(14). PMID: 26958811    Free PMC article.
CoINcIDE: A framework for discovery of patient subtypes across multiple datasets.
Catherine R Planey, Olivier Gevaert.
Genome Med, 2016 Mar 11; 8(1). PMID: 26961683    Free PMC article.
A novel gene expression signature for bone metastasis in breast carcinomas.
C Dilara Savci-Heijink, Hans Halfwerk, Jan Koster, Marc J van de Vijver.
Breast Cancer Res Treat, 2016 Mar 12; 156(2). PMID: 26965286    Free PMC article.
Phase II Randomized Preoperative Window-of-Opportunity Study of the PI3K Inhibitor Pictilisib Plus Anastrozole Compared With Anastrozole Alone in Patients With Estrogen Receptor-Positive Breast Cancer.
Peter Schmid, Sarah E Pinder, +23 authors, Alastair Thompson.
J Clin Oncol, 2016 Mar 16; 34(17). PMID: 26976426    Free PMC article.
Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors.
Shom Goel, Qi Wang, +15 authors, Jean J Zhao.
Cancer Cell, 2016 Mar 16; 29(3). PMID: 26977878    Free PMC article.
Highly Cited.
Genomic markers of panitumumab resistance including ERBB2/ HER2 in a phase II study of KRAS wild-type (wt) metastatic colorectal cancer (mCRC).
Garrett S Barry, Maggie C Cheang, Hector Li Chang, Hagen F Kennecke.
Oncotarget, 2016 Mar 17; 7(14). PMID: 26980732    Free PMC article.
Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkers.
James R Bradford, Mark Wappett, +9 authors, Simon T Barry.
Oncotarget, 2016 Mar 17; 7(15). PMID: 26980748    Free PMC article.
Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer.
Marc A Becker, Yasir H Ibrahim, +8 authors, Douglas Yee.
PLoS One, 2016 Mar 19; 11(3). PMID: 26991655    Free PMC article.
Upregulation of E2F8 promotes cell proliferation and tumorigenicity in breast cancer by modulating G1/S phase transition.
Liping Ye, Ling Guo, +8 authors, Huanxin Lin.
Oncotarget, 2016 Mar 19; 7(17). PMID: 26992224    Free PMC article.
Translating neoadjuvant therapy into survival benefits: one size does not fit all.
Leticia De Mattos-Arruda, Ronglai Shen, Jorge S Reis-Filho, Javier Cortés.
Nat Rev Clin Oncol, 2016 Mar 24; 13(9). PMID: 27000962    Free PMC article.
Review.
Equivalence of MammaPrint array types in clinical trials and diagnostics.
Inès Beumer, Anke Witteveen, +11 authors, Annuska Glas.
Breast Cancer Res Treat, 2016 Mar 24; 156(2). PMID: 27002507    Free PMC article.
EPIG-Seq: extracting patterns and identifying co-expressed genes from RNA-Seq data.
Jianying Li, Pierre R Bushel.
BMC Genomics, 2016 Mar 24; 17. PMID: 27004791    Free PMC article.
Identification and prioritization of candidate genes for symptom variability in breast cancer survivors based on disease characteristics at the cellular level.
Theresa A Koleck, Yvette P Conley.
Breast Cancer (Dove Med Press), 2016 Mar 30; 8. PMID: 27022301    Free PMC article.
Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments.
Barrie Peck, Zachary T Schug, +21 authors, Almut Schulze.
Cancer Metab, 2016 Apr 05; 4. PMID: 27042297    Free PMC article.
Highly Cited.
The Bag-1 inhibitor, Thio-2, reverses an atypical 3D morphology driven by Bag-1L overexpression in a MCF-10A model of ductal carcinoma in situ.
E S Papadakis, C R Barker, +6 authors, R I Cutress.
Oncogenesis, 2016 Apr 05; 5. PMID: 27043661    Free PMC article.
Shared kernel Bayesian screening.
Eric F Lock, David B Dunson.
Biometrika, 2016 Apr 06; 102(4). PMID: 27046939    Free PMC article.
G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis.
Matthew J Billard, David J Fitzhugh, +11 authors, Teresa K Tarrant.
PLoS One, 2016 Apr 07; 11(4). PMID: 27049755    Free PMC article.
A four gene signature of chromosome instability (CIN4) predicts for benefit from taxanes in the NCIC-CTG MA21 clinical trial.
Melanie Spears, Nicola Lyttle, +8 authors, John M S Bartlett.
Oncotarget, 2016 Apr 09; 7(31). PMID: 27056899    Free PMC article.
Epigenetic and genetic burden measures are associated with tumor characteristics in invasive breast carcinoma.
Dylan E O'Sullivan, Kevin C Johnson, +2 authors, Brock C Christensen.
Epigenetics, 2016 Apr 14; 11(5). PMID: 27070496    Free PMC article.
Genes associated with histopathologic features of triple negative breast tumors predict molecular subtypes.
Kristen S Purrington, Daniel W Visscher, +28 authors, Fergus J Couch.
Breast Cancer Res Treat, 2016 Apr 17; 157(1). PMID: 27083182    Free PMC article.
Signatures of breast cancer metastasis at a glance.
George S Karagiannis, Sumanta Goswami, +2 authors, John S Condeelis.
J Cell Sci, 2016 Apr 17; 129(9). PMID: 27084578    Free PMC article.
Review.
Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer.
Andrew R Green, D Soria, +9 authors, I O Ellis.
Breast Cancer Res Treat, 2016 Apr 27; 157(1). PMID: 27116185    Free PMC article.
Comparing Breast Cancer Multiparameter Tests in the OPTIMA Prelim Trial: No Test Is More Equal Than the Others.
John M S Bartlett, Jane Bayani, +18 authors, OPTIMA TMG.
J Natl Cancer Inst, 2016 May 01; 108(9). PMID: 27130929    Free PMC article.
MR Imaging Radiomics Signatures for Predicting the Risk of Breast Cancer Recurrence as Given by Research Versions of MammaPrint, Oncotype DX, and PAM50 Gene Assays.
Hui Li, Yitan Zhu, +13 authors, Maryellen L Giger.
Radiology, 2016 Oct 19; 281(2). PMID: 27144536    Free PMC article.
Highly Cited.
Identifying Network Perturbation in Cancer.
Maxim Grechkin, Benjamin A Logsdon, Andrew J Gentles, Su-In Lee.
PLoS Comput Biol, 2016 May 06; 12(5). PMID: 27145341    Free PMC article.
Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers.
Adam D Pfefferle, Yash N Agrawal, +5 authors, Charles M Perou.
Dis Model Mech, 2016 May 07; 9(7). PMID: 27149990    Free PMC article.
MetaKTSP: a meta-analytic top scoring pair method for robust cross-study validation of omics prediction analysis.
SungHwan Kim, Chien-Wei Lin, George C Tseng.
Bioinformatics, 2016 May 07; 32(13). PMID: 27153719    Free PMC article.
Active smoking and risk of Luminal and Basal-like breast cancer subtypes in the Carolina Breast Cancer Study.
Eboneé N Butler, Chiu-Kit Tse, +3 authors, Melissa A Troester.
Cancer Causes Control, 2016 May 08; 27(6). PMID: 27153846    Free PMC article.
Characterization of patient-derived tumor xenografts (PDXs) as models for estrogen receptor positive (ER+HER2- and ER+HER2+) breast cancers.
Noriko Kanaya, George Somlo, +17 authors, Shiuan Chen.
J Steroid Biochem Mol Biol, 2016 May 08; 170. PMID: 27154416    Free PMC article.
Determining breast cancer histological grade from RNA-sequencing data.
Mei Wang, Daniel Klevebring, +3 authors, Mattias Rantalainen.
Breast Cancer Res, 2016 May 12; 18(1). PMID: 27165105    Free PMC article.
Characterisation of the triple negative breast cancer phenotype associated with the development of central nervous system metastases.
Katerin Rojas Laimito, Angelo Gámez-Pozo, +5 authors, Eva Ciruelos.
Ecancermedicalscience, 2016 May 14; 10. PMID: 27170832    Free PMC article.
Review.
Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant.
Jill M Spoerke, Steven Gendreau, +13 authors, Mark R Lackner.
Nat Commun, 2016 May 14; 7. PMID: 27174596    Free PMC article.
Highly Cited.
Multiplexed immunofluorescence delineates proteomic cancer cell states associated with metabolism.
Anup Sood, Alexandra M Miller, +15 authors, Ingo K Mellinghoff.
JCI Insight, 2016 May 18; 1(6). PMID: 27182557    Free PMC article.
Functional cooperation between KCa3.1 and TRPC1 channels in human breast cancer: Role in cell proliferation and patient prognosis.
Malika Faouzi, Frederic Hague, +4 authors, Halima Ouadid-Ahidouch.
Oncotarget, 2016 May 18; 7(24). PMID: 27183905    Free PMC article.
Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease.
Giampaolo Bianchini, Justin M Balko, +2 authors, Luca Gianni.
Nat Rev Clin Oncol, 2016 Oct 19; 13(11). PMID: 27184417    Free PMC article.
Highly Cited. Review.
Intratumor Heterogeneity Affects Gene Expression Profile Test Prognostic Risk Stratification in Early Breast Cancer.
Rekha Gyanchandani, Yan Lin, +10 authors, Adrian V Lee.
Clin Cancer Res, 2016 Nov 03; 22(21). PMID: 27185370    Free PMC article.
TransCONFIRM: Identification of a Genetic Signature of Response to Fulvestrant in Advanced Hormone Receptor-Positive Breast Cancer.
Rinath Jeselsohn, William T Barry, +10 authors, Luca Malorni.
Clin Cancer Res, 2016 Nov 01; 22(23). PMID: 27185372    Free PMC article.
Neoadjuvant Sequential Docetaxel Followed by High-Dose Epirubicin in Combination With Cyclophosphamide Administered Concurrently With Trastuzumab. The DECT Trial.
Laura Pizzuti, Maddalena Barba, +18 authors, Patrizia Vici.
J Cell Physiol, 2016 May 18; 231(11). PMID: 27187274    Free PMC article.
Immunogenic Subtypes of Breast Cancer Delineated by Gene Classifiers of Immune Responsiveness.
Lance D Miller, Jeff A Chou, +13 authors, Francesco M Marincola.
Cancer Immunol Res, 2016 May 20; 4(7). PMID: 27197066    Free PMC article.
MYC Is a Crucial Mediator of TGFβ-Induced Invasion in Basal Breast Cancer.
Magdalena A Cichon, Megan E Moruzzi, +6 authors, Derek C Radisky.
Cancer Res, 2016 May 20; 76(12). PMID: 27197167    Free PMC article.
High prevalence of luminal B breast cancer intrinsic subtype in Colombian women.
Silvia Juliana Serrano-Gomez, Maria Carolina Sanabria-Salas, +7 authors, Jovanny Zabaleta.
Carcinogenesis, 2016 May 22; 37(7). PMID: 27207651    Free PMC article.
Screening of biomarkers for prediction of response to and prognosis after chemotherapy for breast cancers.
Feng Bing, Yu Zhao.
Onco Targets Ther, 2016 May 25; 9. PMID: 27217777    Free PMC article.
Big data and computational biology strategy for personalized prognosis.
Ghim Siong Ow, Zhiqun Tang, Vladimir A Kuznetsov.
Oncotarget, 2016 Oct 26; 7(26). PMID: 27229533    Free PMC article.
Development and clinical application of an integrative genomic approach to personalized cancer therapy.
Andrew V Uzilov, Wei Ding, +41 authors, Rong Chen.
Genome Med, 2016 Jun 02; 8(1). PMID: 27245685    Free PMC article.
Targeting FOSB with a cationic antimicrobial peptide, TP4, for treatment of triple-negative breast cancer.
Chen-Hung Ting, Yi-Chun Chen, Chang-Jer Wu, Jyh-Yih Chen.
Oncotarget, 2016 Oct 27; 7(26). PMID: 27248170    Free PMC article.
Proteogenomics connects somatic mutations to signalling in breast cancer.
Philipp Mertins, D R Mani, +34 authors, NCI CPTAC.
Nature, 2016 Jun 03; 534(7605). PMID: 27251275    Free PMC article.
Highly Cited.
Expression signature distinguishing two tumour transcriptome classes associated with progression-free survival among rare histological types of epithelial ovarian cancer.
Chen Wang, Boris J Winterhoff, +10 authors, Brooke L Fridley.
Br J Cancer, 2016 Jun 03; 114(12). PMID: 27253175    Free PMC article.
Breast cancer subtype predictors revisited: from consensus to concordance?
Herman M J Sontrop, Marcel J T Reinders, Perry D Moerland.
BMC Med Genomics, 2016 Jun 05; 9(1). PMID: 27259591    Free PMC article.
DNA polymerase θ (POLQ), double-strand break repair, and cancer.
Richard D Wood, Sylvie Doublié.
DNA Repair (Amst), 2016 Jun 07; 44. PMID: 27264557    Free PMC article.
Highly Cited. Review.
Targeted gene silencing of CCL2 inhibits triple negative breast cancer progression by blocking cancer stem cell renewal and M2 macrophage recruitment.
Wei Bin Fang, Min Yao, +4 authors, Nikki Cheng.
Oncotarget, 2016 Jun 11; 7(31). PMID: 27283985    Free PMC article.
Breast cancer subtype dictates DNA methylation and ALDH1A3-mediated expression of tumor suppressor RARRES1.
Krysta M Coyle, J Patrick Murphy, +13 authors, Paola Marcato.
Oncotarget, 2016 Jun 11; 7(28). PMID: 27286452    Free PMC article.
Extent of ductal carcinoma in situ according to breast cancer subtypes: a population-based cohort study.
Shusma C Doebar, Esther C van den Broek, +4 authors, Carolien H M van Deurzen.
Breast Cancer Res Treat, 2016 Jun 20; 158(1). PMID: 27318854    Free PMC article.
The Role of Proliferation in Determining Response to Neoadjuvant Chemotherapy in Breast Cancer: A Gene Expression-Based Meta-Analysis.
Daniel G Stover, Jonathan L Coloff, +3 authors, Laura M Selfors.
Clin Cancer Res, 2016 Jun 23; 22(24). PMID: 27330058    Free PMC article.
Meta-analytic framework for sparse K-means to identify disease subtypes in multiple transcriptomic studies.
Zhiguang Huo, Ying Ding, +2 authors, George Tseng.
J Am Stat Assoc, 2016 Jun 23; 111(513). PMID: 27330233    Free PMC article.
Treatment and survival patterns of Chinese patients diagnosed with breast cancer between 2005 and 2009 in Southwest China: An observational, population-based cohort study.
Zuxiang Peng, Jia Wei, +5 authors, Jing Jing.
Medicine (Baltimore), 2016 Jun 24; 95(25). PMID: 27336872    Free PMC article.
The value of genomics in dissecting the RAS-network and in guiding therapeutics for RAS-driven cancers.
Gajendra Shrestha, Shelley M MacNeil, +3 authors, Andrea H Bild.
Semin Cell Dev Biol, 2016 Jun 25; 58. PMID: 27338857    Free PMC article.
Review.
Gene Expression Profiling of Breast Cancer Brain Metastasis.
Ji Yun Lee, Kyunghee Park, +11 authors, Yeon Hee Park.
Sci Rep, 2016 Jun 25; 6. PMID: 27340107    Free PMC article.
Cancer subtypes classification using long non-coding RNA.
Ronan Flippot, Gabriel G Malouf, +3 authors, David Khayat.
Oncotarget, 2016 Jun 25; 7(33). PMID: 27340923    Free PMC article.
Review.
Extensive Transcriptomic and Genomic Analysis Provides New Insights about Luminal Breast Cancers.
Inna Tishchenko, Heloisa Helena Milioli, Carlos Riveros, Pablo Moscato.
PLoS One, 2016 Jun 25; 11(6). PMID: 27341628    Free PMC article.
p62/SQSTM1 enhances breast cancer stem-like properties by stabilizing MYC mRNA.
L-Z Xu, S-S Li, +12 authors, Q Liu.
Oncogene, 2016 Jun 28; 36(3). PMID: 27345399    Free PMC article.
PTPRO represses ERBB2-driven breast oncogenesis by dephosphorylation and endosomal internalization of ERBB2.
H Dong, L Ma, +11 authors, H Zhang.
Oncogene, 2016 Jun 28; 36(3). PMID: 27345410    Free PMC article.
Metabolic clusters of breast cancer in relation to gene- and protein expression subtypes.
Tonje H Haukaas, Leslie R Euceda, +13 authors, Oslo Breast Cancer Consortium (OSBREAC).
Cancer Metab, 2016 Jun 29; 4. PMID: 27350877    Free PMC article.
Proteomic analysis of breast tumors confirms the mRNA intrinsic molecular subtypes using different classifiers: a large-scale analysis of fresh frozen tissue samples.
Sofia Waldemarson, Emila Kurbasic, +4 authors, Peter James.
Breast Cancer Res, 2016 Jul 01; 18(1). PMID: 27357824    Free PMC article.
Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia.
Syed Haider, Alan McIntyre, +4 authors, Francesca M Buffa.
Genome Biol, 2016 Jul 01; 17(1). PMID: 27358048    Free PMC article.
Prognostic significance of PLIN1 expression in human breast cancer.
Cefan Zhou, Ming Wang, +8 authors, Jingfeng Tang.
Oncotarget, 2016 Jul 01; 7(34). PMID: 27359054    Free PMC article.
A high-resolution transcriptome map of cell cycle reveals novel connections between periodic genes and cancer.
Daniel Dominguez, Yi-Hsuan Tsai, +3 authors, Zefeng Wang.
Cell Res, 2016 Jul 02; 26(8). PMID: 27364684    Free PMC article.
2-(fluorine-18)-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography after breast conserving surgery: Correlation with molecular markers of breast cancer.
Salih Ozguven, Sabahat Inanir, +3 authors, Bahadir Gulluoglu.
Indian J Nucl Med, 2016 Jul 08; 31(3). PMID: 27385883    Free PMC article.
Genomic agonism and phenotypic antagonism between estrogen and progesterone receptors in breast cancer.
Hari Singhal, Marianne E Greene, +10 authors, Geoffrey L Greene.
Sci Adv, 2016 Jul 08; 2(6). PMID: 27386569    Free PMC article.
Expression and methylation patterns partition luminal-A breast tumors into distinct prognostic subgroups.
Dvir Netanely, Ayelet Avraham, +2 authors, Ron Shamir.
Breast Cancer Res, 2016 Jul 09; 18(1). PMID: 27386846    Free PMC article.
Technical validation of an RT-qPCR in vitro diagnostic test system for the determination of breast cancer molecular subtypes by quantification of ERBB2, ESR1, PGR and MKI67 mRNA levels from formalin-fixed paraffin-embedded breast tumor specimens.
Mark Laible, Kornelia Schlombs, +8 authors, Ugur Sahin.
BMC Cancer, 2016 Jul 09; 16. PMID: 27389414    Free PMC article.
A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers.
Anthony Ferrari, Anne Vincent-Salomon, +40 authors, Gilles Thomas.
Nat Commun, 2016 Jul 14; 7. PMID: 27406316    Free PMC article.
Induction of HOXA9 expression in three-dimensional organotypic culture of the Claudin-low breast cancer cells.
Miao Li, Xi Li, +6 authors, Bin Shan.
Oncotarget, 2016 Jul 14; 7(32). PMID: 27409175    Free PMC article.
Consensus of gene expression phenotypes and prognostic risk predictors in primary lung adenocarcinoma.
Markus Ringnér, Johan Staaf.
Oncotarget, 2016 Jul 21; 7(33). PMID: 27437773    Free PMC article.
Retrospective analysis of molecular scores for the prediction of distant recurrence according to baseline risk factors.
Ivana Sestak, Mitch Dowsett, +2 authors, Jack Cuzick.
Breast Cancer Res Treat, 2016 Jul 23; 159(1). PMID: 27447876    Free PMC article.
Ultraconserved long non-coding RNA uc.63 in breast cancer.
Alberto Marini, Anna Maria Lena, +8 authors, Gerry Melino.
Oncotarget, 2016 Jul 23; 8(22). PMID: 27447964    Free PMC article.
Atypical ubiquitin ligase RNF31: the nuclear factor modulator in breast cancer progression.
Jian Zhu, Ting Zhuang, +3 authors, Hui Wang.
BMC Cancer, 2016 Jul 28; 16. PMID: 27460922    Free PMC article.
Review.
Loss of Dickkopf 3 Promotes the Tumorigenesis of Basal Breast Cancer.
Eva Lorsy, Aylin Sophie Topuz, +8 authors, Edgar Dahl.
PLoS One, 2016 Jul 29; 11(7). PMID: 27467270    Free PMC article.
The effects of lymph node status on predicting outcome in ER+ /HER2- tamoxifen treated breast cancer patients using gene signatures.
Jessica G Cockburn, Robin M Hallett, +5 authors, Anita Bane.
BMC Cancer, 2016 Jul 30; 16. PMID: 27469239    Free PMC article.
Relevance of Pathological Complete Response after Neoadjuvant Therapy for Breast Cancer.
Angela Pennisi, Thomas Kieber-Emmons, Issam Makhoul, Laura Hutchins.
Breast Cancer (Auckl), 2016 Aug 02; 10. PMID: 27478380    Free PMC article.
Review.
LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer.
Aldema Sas-Chen, Miriam R Aure, +17 authors, Yosef Yarden.
EMBO Mol Med, 2016 Aug 04; 8(9). PMID: 27485121    Free PMC article.
Exercise and Prognosis on the Basis of Clinicopathologic and Molecular Features in Early-Stage Breast Cancer: The LACE and Pathways Studies.
Lee W Jones, Marilyn L Kwan, +13 authors, Bette J Caan.
Cancer Res, 2016 Aug 05; 76(18). PMID: 27488523    Free PMC article.
Amplification of TLK2 Induces Genomic Instability via Impairing the G2-M Checkpoint.
Jin-Ah Kim, Meenakshi Anurag, +3 authors, Xiao-Song Wang.
Mol Cancer Res, 2016 Aug 05; 14(10). PMID: 27489360    Free PMC article.
A 12-gene signature to distinguish colon cancer patients with better clinical outcome following treatment with 5-fluorouracil or FOLFIRI.
Eric R Paquet, Jing Cui, +9 authors, Michel Lebel.
J Pathol Clin Res, 2016 Aug 09; 1(3). PMID: 27499901    Free PMC article.
Nottingham Prognostic Index Plus: Validation of a clinical decision making tool in breast cancer in an independent series.
Andrew R Green, Daniele Soria, +13 authors, Ian O Ellis.
J Pathol Clin Res, 2016 Aug 09; 2(1). PMID: 27499914    Free PMC article.
High-throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium.
Mustapha Abubakar, William J Howat, +40 authors, Montserrat Garcia-Closas.
J Pathol Clin Res, 2016 Aug 09; 2(3). PMID: 27499923    Free PMC article.
Weighted K-means support vector machine for cancer prediction.
SungHwan Kim.
Springerplus, 2016 Aug 12; 5(1). PMID: 27512621    Free PMC article.
PTEN Loss in E-Cadherin-Deficient Mouse Mammary Epithelial Cells Rescues Apoptosis and Results in Development of Classical Invasive Lobular Carcinoma.
Mirjam C Boelens, Micha Nethe, +9 authors, Jos Jonkers.
Cell Rep, 2016 Aug 16; 16(8). PMID: 27524621    Free PMC article.
Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival.
Yubao Wang, Michael Begley, +7 authors, Jean J Zhao.
Proc Natl Acad Sci U S A, 2016 Aug 17; 113(35). PMID: 27528663    Free PMC article.
Tumour hypoxia causes DNA hypermethylation by reducing TET activity.
Bernard Thienpont, Jessica Steinbacher, +16 authors, Diether Lambrechts.
Nature, 2016 Aug 18; 537(7618). PMID: 27533040    Free PMC article.
Highly Cited.
ERα-XPO1 Cross Talk Controls Tamoxifen Sensitivity in Tumors by Altering ERK5 Cellular Localization.
Kinga Wrobel, Yiru Chen Zhao, +10 authors, Zeynep Madak-Erdogan.
Mol Endocrinol, 2016 Aug 18; 30(10). PMID: 27533791    Free PMC article.
The prognostic potential of alternative transcript isoforms across human tumors.
Juan L Trincado, E Sebestyén, A Pagés, E Eyras.
Genome Med, 2016 Aug 19; 8(1). PMID: 27535130    Free PMC article.
The Role of Genomic Profiling in Advanced Breast Cancer: The Two Faces of Janus.
Yesim Eralp.
Transl Oncogenomics, 2016 Aug 23; 8(Suppl 1). PMID: 27547031    Free PMC article.
Review.
CrossLink: a novel method for cross-condition classification of cancer subtypes.
Chifeng Ma, Konduru S Sastry, +7 authors, Yufei Huang.
BMC Genomics, 2016 Aug 25; 17 Suppl 7. PMID: 27556419    Free PMC article.
Association mining of mutated cancer genes in different clinical stages across 11 cancer types.
Wangxiong Hu, Xiaofen Li, Tingzhang Wang, Shu Zheng.
Oncotarget, 2016 Aug 25; 7(42). PMID: 27556693    Free PMC article.
Breast Cancer Prognostics Using Multi-Omics Data.
Sisi Ma, Jiwen Ren, David Fenyö.
AMIA Jt Summits Transl Sci Proc, 2016 Aug 30; 2016. PMID: 27570650    Free PMC article.
Brachyury, a vaccine target, is overexpressed in triple-negative breast cancer.
Duane H Hamilton, Mario Roselli, +5 authors, Fiorella Guadagni.
Endocr Relat Cancer, 2016 Sep 02; 23(10). PMID: 27580659    Free PMC article.
DMBA induced mouse mammary tumors display high incidence of activating Pik3caH1047 and loss of function Pten mutations.
Martín C Abba, Yi Zhong, +7 authors, C Marcelo Aldaz.
Oncotarget, 2016 Sep 03; 7(39). PMID: 27588403    Free PMC article.
Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity.
Barbara Mair, Tomasz Konopka, +6 authors, Sebastian M B Nijman.
PLoS Genet, 2016 Sep 03; 12(9). PMID: 27588951    Free PMC article.
Molecular subtypes and imaging phenotypes of breast cancer.
Nariya Cho.
Ultrasonography, 2016 Sep 08; 35(4). PMID: 27599892    Free PMC article.
Review.
Modeling anti-IL-6 therapy using breast cancer patient-derived xenografts.
Beatriz Morancho, Mariano Zacarías-Fluck, +6 authors, Isabel T Rubio.
Oncotarget, 2016 Sep 08; 7(42). PMID: 27602583    Free PMC article.
Statins affect ETS1-overexpressing triple-negative breast cancer cells by restoring DUSP4 deficiency.
Hae Hyun Jung, Soo-Hyeon Lee, +3 authors, Young-Hyuck Im.
Sci Rep, 2016 Sep 09; 6. PMID: 27604655    Free PMC article.
Improving Pathological Assessment of Breast Cancer by Employing Array-Based Transcriptome Analysis.
Zsuzsanna Mihály, Balázs Győrffy.
Microarrays (Basel), 2013 Jan 01; 2(3). PMID: 27605190    Free PMC article.
Review.
From High-Throughput Microarray-Based Screening to Clinical Application: The Development of a Second Generation Multigene Test for Breast Cancer Prognosis.
Jan C Brase, Ralf Kronenwett, +2 authors, Marcus Schmidt.
Microarrays (Basel), 2013 Jan 01; 2(3). PMID: 27605191    Free PMC article.
Review.
Portraying breast cancers with long noncoding RNAs.
Olivier Van Grembergen, Martin Bizet, +9 authors, François Fuks.
Sci Adv, 2016 Sep 13; 2(9). PMID: 27617288    Free PMC article.
Highly Cited.
An integrative and comparative study of pan-cancer transcriptomes reveals distinct cancer common and specific signatures.
Zhen Cao, Shihua Zhang.
Sci Rep, 2016 Sep 17; 6. PMID: 27633916    Free PMC article.
DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer.
Nnennaya Kanu, Maria Antonietta Cerone, +14 authors, Charles Swanton.
Genome Biol, 2016 Sep 17; 17(1). PMID: 27634334    Free PMC article.
Highly Cited.
Prognosis of breast cancer molecular subtypes in routine clinical care: A large prospective cohort study.
André Hennigs, Fabian Riedel, +13 authors, Andreas Schneeweiss.
BMC Cancer, 2016 Sep 17; 16(1). PMID: 27634735    Free PMC article.
Comprehensive landscape of subtype-specific coding and non-coding RNA transcripts in breast cancer.
Trung Nghia Vu, Setia Pramana, +3 authors, Yudi Pawitan.
Oncotarget, 2016 Sep 17; 7(42). PMID: 27634900    Free PMC article.
A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.
Alejandra Bruna, Oscar M Rueda, +27 authors, Carlos Caldas.
Cell, 2016 Sep 20; 167(1). PMID: 27641504    Free PMC article.
Highly Cited.
Bromodomain and Extraterminal Protein Inhibition Blocks Growth of Triple-negative Breast Cancers through the Suppression of Aurora Kinases.
Jennifer M Sahni, Sylvia S Gayle, +9 authors, Ruth A Keri.
J Biol Chem, 2016 Sep 22; 291(45). PMID: 27650498    Free PMC article.
Breast cancer classification and prognostication through diverse systems along with recent emerging findings in this respect; the dawn of new perspectives in the clinical applications.
Vida Pourteimoor, Samira Mohammadi-Yeganeh, Mahdi Paryan.
Tumour Biol, 2016 Sep 22; 37(11). PMID: 27651157
Review.
αB-crystallin Expression in Breast Cancer is Associated with Brain Metastasis.
K David Voduc, Torsten O Nielsen, +6 authors, Maggie C U Cheang.
NPJ Breast Cancer, 2016 Sep 23; 1. PMID: 27656679    Free PMC article.
The Anti-Cancer Effect of Polyphenols against Breast Cancer and Cancer Stem Cells: Molecular Mechanisms.
Ahmed Abdal Dayem, Hye Yeon Choi, +3 authors, Ssang-Goo Cho.
Nutrients, 2016 Sep 23; 8(9). PMID: 27657126    Free PMC article.
Review.
Mammary Tumor-Associated RNAs Impact Tumor Cell Proliferation, Invasion, and Migration.
Sarah D Diermeier, Kung-Chi Chang, +6 authors, David L Spector.
Cell Rep, 2016 Sep 30; 17(1). PMID: 27681436    Free PMC article.
Repression of p63 and induction of EMT by mutant Ras in mammary epithelial cells.
Kathryn E Yoh, Kausik Regunath, +6 authors, Ron Prywes.
Proc Natl Acad Sci U S A, 2016 Sep 30; 113(41). PMID: 27681615    Free PMC article.
Molecular Classification of Breast Cancer Tumours from Patients Treated with Doxorubicin and Docetaxel.
Atocha Romero Alfonso.
EJIFCC, 2010 Jan 01; 20(4). PMID: 27683343    Free PMC article.
RNA Sequencing to Predict Response to Neoadjuvant Anti-HER2 Therapy: A Secondary Analysis of the NeoALTTO Randomized Clinical Trial.
Debora Fumagalli, David Venet, +20 authors, Christos Sotiriou.
JAMA Oncol, 2016 Sep 30; 3(2). PMID: 27684533    Free PMC article.
Tumor Infiltrating Lymphocytes Affect the Outcome of Patients with Operable Triple-Negative Breast Cancer in Combination with Mutated Amino Acid Classes.
Vassiliki Kotoula, Sotiris Lakis, +18 authors, George Fountzilas.
PLoS One, 2016 Sep 30; 11(9). PMID: 27685159    Free PMC article.
Consensus Analysis of Whole Transcriptome Profiles from Two Breast Cancer Patient Cohorts Reveals Long Non-Coding RNAs Associated with Intrinsic Subtype and the Tumour Microenvironment.
James R Bradford, Angela Cox, Philip Bernard, Nicola J Camp.
PLoS One, 2016 Sep 30; 11(9). PMID: 27685983    Free PMC article.
Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers.
Jin-Ah Kim, Ying Tan, +9 authors, Xiao-Song Wang.
Nat Commun, 2016 Oct 04; 7. PMID: 27694828    Free PMC article.
Chemotherapy response and survival of inflammatory breast cancer by hormone receptor- and HER2-defined molecular subtypes approximation: an analysis from the National Cancer Database.
Jieqiong Liu, Kai Chen, +5 authors, Lisa K Jacobs.
J Cancer Res Clin Oncol, 2016 Oct 06; 143(1). PMID: 27704268
Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium.
Taru A Muranen, Carl Blomqvist, +41 authors, Heli Nevanlinna.
Breast Cancer Res, 2016 Oct 08; 18(1). PMID: 27716369    Free PMC article.
Biological Subtypes and Distant Relapse Pattern in Breast Cancer Patients After Curative Surgery (Study of Anatolian Society of Medical Oncology).
Muhammet A Kaplan, Ulku Y Arslan, +21 authors, Mukremin Uysal.
Breast Care (Basel), 2016 Oct 11; 11(4). PMID: 27721711    Free PMC article.
Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers.
Roni Allaoui, Caroline Bergenfelz, +12 authors, Karin Leandersson.
Nat Commun, 2016 Oct 12; 7. PMID: 27725631    Free PMC article.
Breast cancer molecular subtypes: from TNBC to QNBC.
Jane Date C Hon, Baljit Singh, +7 authors, Peng Lee.
Am J Cancer Res, 2016 Oct 12; 6(9). PMID: 27725895    Free PMC article.
Review.
Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer.
Rico D Bense, Christos Sotiriou, +5 authors, Rudolf S N Fehrmann.
J Natl Cancer Inst, 2016 Oct 16; 109(1). PMID: 27737921    Free PMC article.
Highly Cited.
Impact of the Choice of Normalization Method on Molecular Cancer Class Discovery Using Nonnegative Matrix Factorization.
Haixuan Yang, Cathal Seoighe.
PLoS One, 2016 Oct 16; 11(10). PMID: 27741311    Free PMC article.
CDK4 regulates cancer stemness and is a novel therapeutic target for triple-negative breast cancer.
Meiou Dai, Chenjing Zhang, +7 authors, Jean-Jacques Lebrun.
Sci Rep, 2016 Oct 21; 6. PMID: 27759034    Free PMC article.
Proximal and distal regulation of the HYAL1 gene cluster by the estrogen receptor α in breast cancer cells.
Lydia Edjekouane, Samira Benhadjeba, +4 authors, André Tremblay.
Oncotarget, 2016 Oct 21; 7(47). PMID: 27764788    Free PMC article.
PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.
Fara Brasó-Maristany, Simone Filosto, +25 authors, Andrew N Tutt.
Nat Med, 2016 Nov 01; 22(11). PMID: 27775704    Free PMC article.
Highly Cited.
Exploring the intrinsic differences among breast tumor subtypes defined using immunohistochemistry markers based on the decision tree.
Yang Li, Xu-Qing Tang, Zhonghu Bai, Xiaofeng Dai.
Sci Rep, 2016 Oct 28; 6. PMID: 27786176    Free PMC article.
Intrinsic Subtype and Therapeutic Response Among HER2-Positive Breaty st Tumors from the NCCTG (Alliance) N9831 Trial.
Edith A Perez, Karla V Ballman, +10 authors, E Aubrey Thompson.
J Natl Cancer Inst, 2016 Oct 30; 109(2). PMID: 27794124    Free PMC article.
Over-Expression of POU Class 1 Homeobox 1 Transcription Factor (Pit-1) Predicts Poor Prognosis for Breast Cancer Patients.
Zhongcheng Gao, Kecheng Xue, Lianfang Zhang, Meng Wei.
Med Sci Monit, 2016 Nov 01; 22. PMID: 27798557    Free PMC article.
The expression pattern of matrix-producing tumor stroma is of prognostic importance in breast cancer.
Sofia Winslow, Kajsa Ericson Lindquist, Anders Edsjö, Christer Larsson.
BMC Cancer, 2016 Nov 05; 16(1). PMID: 27809802    Free PMC article.
Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression.
Roberto Rangel, Song-Choon Lee, +12 authors, Neal G Copeland.
Proc Natl Acad Sci U S A, 2016 Nov 17; 113(48). PMID: 27849608    Free PMC article.
Epigenomic Deconvolution of Breast Tumors Reveals Metabolic Coupling between Constituent Cell Types.
Vitor Onuchic, Ryan J Hartmaier, +8 authors, Aleksandar Milosavljevic.
Cell Rep, 2016 Nov 17; 17(8). PMID: 27851969    Free PMC article.
Quantitative MRI radiomics in the prediction of molecular classifications of breast cancer subtypes in the TCGA/TCIA data set.
Hui Li, Yitan Zhu, +13 authors, Maryellen L Giger.
NPJ Breast Cancer, 2016 Nov 18; 2. PMID: 27853751    Free PMC article.
Highly Cited.
Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer.
Gabriele Corda, Gianluca Sala, +22 authors, Arturo Sala.
J Pathol, 2016 Nov 20; 241(3). PMID: 27859262    Free PMC article.
The molecular basis of breast cancer pathological phenotypes.
Yujing J Heng, Susan C Lester, +26 authors, Andrew H Beck.
J Pathol, 2016 Nov 20; 241(3). PMID: 27861902    Free PMC article.
Oestrogen receptor negativity in breast cancer: a cause or consequence?
Vijaya Narasihma Reddy Gajulapalli, Vijaya Lakshmi Malisetty, Suresh Kumar Chitta, Bramanandam Manavathi.
Biosci Rep, 2016 Nov 26; 36(6). PMID: 27884978    Free PMC article.
Review.
Hormonal Modulation of Breast Cancer Gene Expression: Implications for Intrinsic Subtyping in Premenopausal Women.
Sarah M Bernhardt, Pallave Dasari, +3 authors, Wendy V Ingman.
Front Oncol, 2016 Nov 30; 6. PMID: 27896218    Free PMC article.
Review.
FREQUENT SUBGRAPH MINING OF PERSONALIZED SIGNALING PATHWAY NETWORKS GROUPS PATIENTS WITH FREQUENTLY DYSREGULATED DISEASE PATHWAYS AND PREDICTS PROGNOSIS.
Arda Durmaz, Tim A D Henderson, Douglas Brubaker, Gurkan Bebek.
Pac Symp Biocomput, 2016 Nov 30; 22. PMID: 27896993    Free PMC article.
Sequencing-based breast cancer diagnostics as an alternative to routine biomarkers.
Mattias Rantalainen, Daniel Klevebring, +10 authors, Henrik Grönberg.
Sci Rep, 2016 Dec 03; 6. PMID: 27901097    Free PMC article.
Accurate prediction of response to endocrine therapy in breast cancer patients: current and future biomarkers.
Cigdem Selli, J Michael Dixon, Andrew H Sims.
Breast Cancer Res, 2016 Dec 03; 18(1). PMID: 27903276    Free PMC article.
Review.
Distinct Receptor Tyrosine Kinase Subsets Mediate Anti-HER2 Drug Resistance in Breast Cancer.
Peter B Alexander, Rui Chen, +9 authors, Xiao-Fan Wang.
J Biol Chem, 2016 Dec 03; 292(2). PMID: 27903634    Free PMC article.
A PAM50-Based Chemoendocrine Score for Hormone Receptor-Positive Breast Cancer with an Intermediate Risk of Relapse.
Aleix Prat, Ana Lluch, +22 authors, Emilio Alba.
Clin Cancer Res, 2016 Dec 03; 23(12). PMID: 27903675    Free PMC article.
DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival.
Thomas Fleischer, Jovana Klajic, +15 authors, Vessela N Kristensen.
Oncotarget, 2016 Dec 03; 8(1). PMID: 27911866    Free PMC article.
Androgen Receptor: A Complex Therapeutic Target for Breast Cancer.
Ramesh Narayanan, James T Dalton.
Cancers (Basel), 2016 Dec 06; 8(12). PMID: 27918430    Free PMC article.
Review.
Transcriptional Network Architecture of Breast Cancer Molecular Subtypes.
Guillermo de Anda-Jáuregui, Tadeo E Velázquez-Caldelas, Jesús Espinal-Enríquez, Enrique Hernández-Lemus.
Front Physiol, 2016 Dec 07; 7. PMID: 27920729    Free PMC article.
Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases.
Katherine A Hoadley, Marni B Siegel, +12 authors, Elaine R Mardis.
PLoS Med, 2016 Dec 07; 13(12). PMID: 27923045    Free PMC article.
Combination Epigenetic Therapy in Advanced Breast Cancer with 5-Azacitidine and Entinostat: A Phase II National Cancer Institute/Stand Up to Cancer Study.
Roisin M Connolly, Huili Li, +22 authors, Vered Stearns.
Clin Cancer Res, 2016 Dec 17; 23(11). PMID: 27979916    Free PMC article.
An mRNA Gene Expression-Based Signature to Identify FGFR1-Amplified Estrogen Receptor-Positive Breast Tumors.
Jingqin Luo, Shuzhen Liu, +11 authors, Matthew J Ellis.
J Mol Diagn, 2016 Dec 21; 19(1). PMID: 27993329    Free PMC article.
Optimizing the Use of Gene Expression Profiling in Early-Stage Breast Cancer.
Hyun-Seok Kim, Christopher B Umbricht, +22 authors, Leslie Cope.
J Clin Oncol, 2016 Dec 22; 34(36). PMID: 27998227    Free PMC article.
p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis.
Robert A H van de Ven, Jolien S de Groot, +11 authors, Patrick W B Derksen.
Nat Commun, 2016 Dec 23; 7. PMID: 28004812    Free PMC article.
Patient-derived xenograft (PDX) models in basic and translational breast cancer research.
Lacey E Dobrolecki, Susie D Airhart, +29 authors, Michael T Lewis.
Cancer Metastasis Rev, 2016 Dec 28; 35(4). PMID: 28025748    Free PMC article.
Highly Cited. Review.
Key Survival Factor, Mcl-1, Correlates with Sensitivity to Combined Bcl-2/Bcl-xL Blockade.
Michelle M Williams, Linus Lee, +9 authors, Rebecca S Cook.
Mol Cancer Res, 2017 Jan 01; 15(3). PMID: 28039357    Free PMC article.
Claudin-Low Breast Cancer; Clinical & Pathological Characteristics.
Kay Dias, Anna Dvorkin-Gheva, +6 authors, Anita L Bane.
PLoS One, 2017 Jan 04; 12(1). PMID: 28045912    Free PMC article.
Competing endogenous RNA network analysis identifies critical genes among the different breast cancer subtypes.
Juan Chen, Juan Xu, +9 authors, Yan Zhang.
Oncotarget, 2017 Jan 05; 8(6). PMID: 28052038    Free PMC article.
Splicing imbalances in basal-like breast cancer underpin perturbation of cell surface and oncogenic pathways and are associated with patients' survival.
Filipe Gracio, Brian Burford, +8 authors, Emanuele de Rinaldis.
Sci Rep, 2017 Jan 07; 7. PMID: 28059167    Free PMC article.
The effect of androgen receptor expression on clinical characterization of metastatic breast cancer.
Ji-Yeon Kim, Kyunghee Park, +5 authors, Yeon Hee Park.
Oncotarget, 2017 Jan 07; 8(5). PMID: 28060723    Free PMC article.
Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.
Xiupeng Zhang, Guiyang Jiang, +5 authors, Yong Zhang.
Oncotarget, 2017 Jan 12; 8(8). PMID: 28076326    Free PMC article.
Dissecting the Biology of Menstrual Cycle-Associated Breast Cancer Risk.
Vahid Atashgaran, Joseph Wrin, +2 authors, Wendy V Ingman.
Front Oncol, 2017 Jan 14; 6. PMID: 28083513    Free PMC article.
Review.
Genomic pathways modulated by Twist in breast cancer.
Farhad Vesuna, Yehudit Bergman, Venu Raman.
BMC Cancer, 2017 Jan 15; 17(1). PMID: 28086829    Free PMC article.
Statistical significance for hierarchical clustering.
Patrick K Kimes, Yufeng Liu, David Neil Hayes, James Stephen Marron.
Biometrics, 2017 Jan 19; 73(3). PMID: 28099990    Free PMC article.
Glucocorticoid receptor signalling activates YAP in breast cancer.
Giovanni Sorrentino, Naomi Ruggeri, +10 authors, Giannino Del Sal.
Nat Commun, 2017 Jan 20; 8. PMID: 28102225    Free PMC article.
Highly Cited.
Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex.
Jon S Zawistowski, Samantha M Bevill, +22 authors, Gary L Johnson.
Cancer Discov, 2017 Jan 22; 7(3). PMID: 28108460    Free PMC article.
Highly Cited.
Computational approach for deriving cancer progression roadmaps from static sample data.
Yijun Sun, Jin Yao, +3 authors, Steve Goodison.
Nucleic Acids Res, 2017 Jan 22; 45(9). PMID: 28108658    Free PMC article.
Principal Graph and Structure Learning Based on Reversed Graph Embedding.
Qi Mao, Li Wang, Ivor W Tsang, Yijun Sun.
IEEE Trans Pattern Anal Mach Intell, 2017 Jan 24; 39(11). PMID: 28114001    Free PMC article.
Parity, hormones and breast cancer subtypes - results from a large nested case-control study in a national screening program.
Merete Ellingjord-Dale, Linda Vos, +3 authors, Giske Ursin.
Breast Cancer Res, 2017 Jan 25; 19(1). PMID: 28114999    Free PMC article.
Genome-wide screen identifies a novel prognostic signature for breast cancer survival.
Xuan Y Mao, Matthew J Lee, +3 authors, Antoine M Snijders.
Oncotarget, 2017 Jan 26; 8(8). PMID: 28122328    Free PMC article.
Subtype-specific CpG island shore methylation and mutation patterns in 30 breast cancer cell lines.
Heejoon Chae, Sangseon Lee, Kenneth P Nephew, Sun Kim.
BMC Syst Biol, 2017 Feb 06; 10(Suppl 4). PMID: 28155687    Free PMC article.
High-dimensional omics data analysis using a variable screening protocol with prior knowledge integration (SKI).
Cong Liu, Jianping Jiang, +3 authors, Hui Lu.
BMC Syst Biol, 2017 Feb 06; 10(Suppl 4). PMID: 28155690    Free PMC article.
RNF20 and histone H2B ubiquitylation exert opposing effects in Basal-Like versus luminal breast cancer.
Ohad Tarcic, Roy Z Granit, +8 authors, Moshe Oren.
Cell Death Differ, 2017 Feb 06; 24(4). PMID: 28157208    Free PMC article.
Bevacizumab May Differentially Improve Ovarian Cancer Outcome in Patients with Proliferative and Mesenchymal Molecular Subtypes.
Stefan Kommoss, Boris Winterhoff, +24 authors, Jacobus Pfisterer.
Clin Cancer Res, 2017 Feb 06; 23(14). PMID: 28159814    Free PMC article.
Amplification of SOX4 promotes PI3K/Akt signaling in human breast cancer.
Gaurav A Mehta, Joel S Parker, +3 authors, Michael L Gatza.
Breast Cancer Res Treat, 2017 Feb 09; 162(3). PMID: 28176176    Free PMC article.
Identifying relations between imaging phenotypes and molecular subtypes of breast cancer: Model discovery and external validation.
Jia Wu, Xiaoli Sun, +5 authors, Ruijiang Li.
J Magn Reson Imaging, 2017 Feb 09; 46(4). PMID: 28177554    Free PMC article.
Comparison of immunohistochemistry with PCR for assessment of ER, PR, and Ki-67 and prediction of pathological complete response in breast cancer.
Hans-Peter Sinn, Andreas Schneeweiss, +9 authors, Frederik Marmé.
BMC Cancer, 2017 Feb 15; 17(1). PMID: 28193205    Free PMC article.
Transcriptomic dynamics of breast cancer progression in the MMTV-PyMT mouse model.
Ying Cai, Ruben Nogales-Cadenas, +5 authors, Zhengdong D Zhang.
BMC Genomics, 2017 Feb 19; 18(1). PMID: 28212608    Free PMC article.
MINT: a multivariate integrative method to identify reproducible molecular signatures across independent experiments and platforms.
Florian Rohart, Aida Eslami, +2 authors, Kim-Anh Lê Cao.
BMC Bioinformatics, 2017 Mar 01; 18(1). PMID: 28241739    Free PMC article.
Systematic Identification and Assessment of Therapeutic Targets for Breast Cancer Based on Genome-Wide RNA Interference Transcriptomes.
Yang Liu, Xiaoyao Yin, +7 authors, Hui Bai.
Genes (Basel), 2017 Mar 02; 8(3). PMID: 28245581    Free PMC article.
Intrinsic Subtypes and Gene Expression Profiles in Primary and Metastatic Breast Cancer.
Juan M Cejalvo, Eduardo Martínez de Dueñas, +24 authors, Aleix Prat.
Cancer Res, 2017 Mar 03; 77(9). PMID: 28249905    Free PMC article.
Highly Cited.
Robust stratification of breast cancer subtypes using differential patterns of transcript isoform expression.
Thomas P Stricker, Christopher D Brown, +6 authors, Kevin P White.
PLoS Genet, 2017 Mar 07; 13(3). PMID: 28263985    Free PMC article.
DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms.
David J Lemler, Miranda L Lynch, +7 authors, Frank M Torti.
Breast Cancer Res, 2017 Mar 09; 19(1). PMID: 28270217    Free PMC article.
Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells.
Brian Bierie, Sarah E Pierce, +8 authors, Robert A Weinberg.
Proc Natl Acad Sci U S A, 2017 Mar 09; 114(12). PMID: 28270621    Free PMC article.
Highly Cited.
Pooled Clustering of High-Grade Serous Ovarian Cancer Gene Expression Leads to Novel Consensus Subtypes Associated with Survival and Surgical Outcomes.
Chen Wang, Sebastian M Armasu, +7 authors, Ellen L Goode.
Clin Cancer Res, 2017 Mar 11; 23(15). PMID: 28280090    Free PMC article.
FOXC1: an emerging marker and therapeutic target for cancer.
B Han, N Bhowmick, +3 authors, X Cui.
Oncogene, 2017 Mar 14; 36(28). PMID: 28288141    Free PMC article.
Review.
[Breast cancer in Morocco: phenotypic profile of tumors].
Ahmadaye Ibrahim Khalil, Karima Bendahhou, +2 authors, Abdellatif Benider.
Pan Afr Med J, 2017 Mar 16; 25. PMID: 28292037    Free PMC article.
Down regulation of ADAM33 as a Predictive Biomarker of Aggressive Breast Cancer.
Graciele C M Manica, Caroline F Ribeiro, +12 authors, Giseli Klassen.
Sci Rep, 2017 Mar 16; 7. PMID: 28294120    Free PMC article.
Covariation of Peptide Abundances Accurately Reflects Protein Concentration Differences.
Bo Zhang, Mohammad Pirmoradian, Roman Zubarev, Lukas Käll.
Mol Cell Proteomics, 2017 Mar 18; 16(5). PMID: 28302922    Free PMC article.
Detecting gene signature activation in breast cancer in an absolute, single-patient manner.
E R Paquet, R Lesurf, +2 authors, M T Hallett.
Breast Cancer Res, 2017 Mar 23; 19(1). PMID: 28327201    Free PMC article.
BCIP: a gene-centered platform for identifying potential regulatory genes in breast cancer.
Jiaqi Wu, Shuofeng Hu, +6 authors, Xiaomin Ying.
Sci Rep, 2017 Mar 23; 7. PMID: 28327601    Free PMC article.
Molecular Classification of Breast Carcinoma: From Traditional, Old-Fashioned Way to A New Age, and A New Way.
Nuket Eliyatkın, Evrim Yalçın, +2 authors, Enver Vardar.
J Breast Health, 2015 Jan 01; 11(2). PMID: 28331693    Free PMC article.
Review.
Low Recombination Proficiency Score (RPS) Predicts Heightened Sensitivity to DNA-Damaging Chemotherapy in Breast Cancer.
Sean P Pitroda, Riyue Bao, +2 authors, Philip P Connell.
Clin Cancer Res, 2017 Mar 28; 23(15). PMID: 28341751    Free PMC article.
A Bayesian semiparametric factor analysis model for subtype identification.
Jiehuan Sun, Joshua L Warren, Hongyu Zhao.
Stat Appl Genet Mol Biol, 2017 Mar 28; 16(2). PMID: 28343169    Free PMC article.
Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer.
Dyah L Dewi, Soumya R Mohapatra, +19 authors, Christiane A Opitz.
Oncoimmunology, 2017 Mar 28; 6(2). PMID: 28344890    Free PMC article.
A new molecular prognostic score for predicting the risk of distant metastasis in patients with HR+/HER2- early breast cancer.
Gyungyub Gong, Mi Jeong Kwon, +15 authors, Young Kee Shin.
Sci Rep, 2017 Mar 30; 7. PMID: 28350001    Free PMC article.
Basal-like breast cancer: molecular profiles, clinical features and survival outcomes.
Heloisa H Milioli, Inna Tishchenko, +2 authors, Pablo Moscato.
BMC Med Genomics, 2017 Mar 30; 10(1). PMID: 28351365    Free PMC article.
Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome.
Miriam Ragle Aure, Valeria Vitelli, +32 authors, OSBREAC.
Breast Cancer Res, 2017 Mar 31; 19(1). PMID: 28356166    Free PMC article.
Revealing common disease mechanisms shared by tumors of different tissues of origin through semantic representation of genomic alterations and topic modeling.
Vicky Chen, John Paisley, Xinghua Lu.
BMC Genomics, 2017 Apr 01; 18(Suppl 2). PMID: 28361690    Free PMC article.
Breast cancer in Asian Americans in California, 1988-2013: increasing incidence trends and recent data on breast cancer subtypes.
Scarlett Lin Gomez, Julie Von Behren, +5 authors, Sally L Glaser.
Breast Cancer Res Treat, 2017 Apr 04; 164(1). PMID: 28365834    Free PMC article.
Role of steroid receptor and coregulator mutations in hormone-dependent cancers.
Anna C Groner, Myles Brown.
J Clin Invest, 2017 Apr 04; 127(4). PMID: 28368289    Free PMC article.
Review.
Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breast cancer.
Mizuki Yamamoto, Kota Sakane, +7 authors, Jun-Ichiro Inoue.
Cancer Sci, 2017 Apr 04; 108(6). PMID: 28371195    Free PMC article.
Progesterone Receptor Isoform Ratio: A Breast Cancer Prognostic and Predictive Factor for Antiprogestin Responsiveness.
Paola A Rojas, María May, +12 authors, Claudia Lanari.
J Natl Cancer Inst, 2017 Apr 05; 109(7). PMID: 28376177    Free PMC article.
Personalized Prognostic Prediction Models for Breast Cancer Recurrence and Survival Incorporating Multidimensional Data.
Xifeng Wu, Yuanqing Ye, +11 authors, Gabriel N Hortobagyi.
J Natl Cancer Inst, 2017 Apr 05; 109(7). PMID: 28376179    Free PMC article.
Breast Cancer Patient-Derived Xenografts: Pros, Cons, and Next Steps.
Maryam Nemati Shafaee, Matthew James Ellis.
J Natl Cancer Inst, 2017 Apr 05; 109(7). PMID: 28376181    Free PMC article.
Comparison of triple-negative breast cancer molecular subtyping using RNA from matched fresh-frozen versus formalin-fixed paraffin-embedded tissue.
Bojana Jovanović, Quanhu Sheng, +8 authors, Brian D Lehmann.
BMC Cancer, 2017 Apr 06; 17(1). PMID: 28376728    Free PMC article.
A 3q gene signature associated with triple negative breast cancer organ specific metastasis and response to neoadjuvant chemotherapy.
Jun Qian, Heidi Chen, +4 authors, Pierre P Massion.
Sci Rep, 2017 Apr 08; 7. PMID: 28387221    Free PMC article.
S100β as a serum marker in endocrine resistant breast cancer.
Sara Charmsaz, Éamon Hughes, +10 authors, Leonie S Young.
BMC Med, 2017 Apr 13; 15(1). PMID: 28399921    Free PMC article.
Using the 21-gene assay from core needle biopsies to choose neoadjuvant therapy for breast cancer: A multicenter trial.
Harry D Bear, Wen Wan, +8 authors, Amy P Sing.
J Surg Oncol, 2017 Apr 14; 115(8). PMID: 28407247    Free PMC article.
Association Study Confirmed Three Breast Cancer-Specific Molecular Subtype-Associated Susceptibility Loci in Chinese Han Women.
Yihui Xu, Mengyun Chen, +7 authors, Bo Zhang.
Oncologist, 2017 Apr 15; 22(8). PMID: 28408616    Free PMC article.
MMP11 and CD2 as novel prognostic factors in hormone receptor-negative, HER2-positive breast cancer.
Jinil Han, Yoon-La Choi, +11 authors, Young Kee Shin.
Breast Cancer Res Treat, 2017 Apr 15; 164(1). PMID: 28409241    Free PMC article.
Fatty acid metabolism in breast cancer subtypes.
Marie E Monaco.
Oncotarget, 2017 Apr 17; 8(17). PMID: 28412757    Free PMC article.
Review.
TFAP2A is a component of the ZEB1/2 network that regulates TGFB1-induced epithelial to mesenchymal transition.
Yoana Dimitrova, Andreas J Gruber, +6 authors, Mihaela Zavolan.
Biol Direct, 2017 Apr 18; 12(1). PMID: 28412966    Free PMC article.
NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress-Induced DPP3-KEAP1 Interaction.
Kevin Lu, Allen L Alcivar, +7 authors, Bing Xia.
Cancer Res, 2017 Apr 19; 77(11). PMID: 28416489    Free PMC article.
Limitations in predicting PAM50 intrinsic subtype and risk of relapse score with Ki67 in estrogen receptor-positive HER2-negative breast cancer.
Aranzazu Fernandez-Martinez, Tomás Pascual, +30 authors, Miguel Martin.
Oncotarget, 2017 Apr 21; 8(13). PMID: 28423537    Free PMC article.
An exploratory study of host polymorphisms in genes that clinically characterize breast cancer tumors and pretreatment cognitive performance in breast cancer survivors.
Theresa A Koleck, Catherine M Bender, +7 authors, Yvette P Conley.
Breast Cancer (Dove Med Press), 2017 Apr 21; 9. PMID: 28424560    Free PMC article.
Clinical implications of genomic profiles in metastatic breast cancer with a focus on TP53 and PIK3CA, the most frequently mutated genes.
Ji-Yeon Kim, Eunjin Lee, +5 authors, Yeon Hee Park.
Oncotarget, 2017 Apr 22; 8(17). PMID: 28427202    Free PMC article.
Immunocompetent mouse allograft models for development of therapies to target breast cancer metastasis.
Yuan Yang, Howard H Yang, +10 authors, Lalage M Wakefield.
Oncotarget, 2017 Apr 22; 8(19). PMID: 28430642    Free PMC article.
A murine preclinical syngeneic transplantation model for breast cancer precision medicine.
Lorenzo Federico, Zechen Chong, +18 authors, Gordon B Mills.
Sci Adv, 2017 Apr 26; 3(4). PMID: 28439535    Free PMC article.
Targeting autophagic cancer stem-cells to reverse chemoresistance in human triple negative breast cancer.
Guilhem Bousquet, Morad El Bouchtaoui, +10 authors, Anne Janin.
Oncotarget, 2017 Apr 27; 8(21). PMID: 28445132    Free PMC article.
Activity of distinct growth factor receptor network components in breast tumors uncovers two biologically relevant subtypes.
Mumtahena Rahman, Shelley M MacNeil, +8 authors, Andrea H Bild.
Genome Med, 2017 Apr 28; 9(1). PMID: 28446242    Free PMC article.
RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signature.
Ryne C Ramaker, Brittany N Lasseigne, +4 authors, Sara J Cooper.
Oncotarget, 2017 Apr 30; 8(24). PMID: 28454104    Free PMC article.
Resistance to Taxanes in Triple-Negative Breast Cancer Associates with the Dynamics of a CD49f+ Tumor-Initiating Population.
Jorge Gómez-Miragaya, Marta Palafox, +19 authors, Eva González-Suárez.
Stem Cell Reports, 2017 May 02; 8(5). PMID: 28457887    Free PMC article.
Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas.
Dezheng Huo, Hai Hu, +17 authors, Olufunmilayo I Olopade.
JAMA Oncol, 2017 May 05; 3(12). PMID: 28472234    Free PMC article.
Highly Cited.
MiSTIC, an integrated platform for the analysis of heterogeneity in large tumour transcriptome datasets.
Sebastien Lemieux, Tobias Sargeant, +10 authors, Guy Sauvageau.
Nucleic Acids Res, 2017 May 05; 45(13). PMID: 28472340    Free PMC article.
A New Gene Expression Signature for Triple Negative Breast Cancer Using Frozen Fresh Tissue before Neoadjuvant Chemotherapy.
Sandra Karina Santuario-Facio, Servando Cardona-Huerta, +16 authors, Rocio Ortiz-Lopez.
Mol Med, 2017 May 06; 23. PMID: 28474731    Free PMC article.
CDK4/6 Inhibition in Breast Cancer: Mechanisms of Response and Treatment Failure.
Ana C Garrido-Castro, Shom Goel.
Curr Breast Cancer Rep, 2017 May 10; 9(1). PMID: 28479958    Free PMC article.
Transcriptional response profiles of paired tumor-normal samples offer novel perspectives in pan-cancer analysis.
Shuofeng Hu, Hanyu Yuan, +7 authors, Xiaomin Ying.
Oncotarget, 2017 May 11; 8(25). PMID: 28489584    Free PMC article.
Associations of Luminal and Basal Subtyping of Prostate Cancer With Prognosis and Response to Androgen Deprivation Therapy.
Shuang G Zhao, S Laura Chang, +25 authors, Felix Y Feng.
JAMA Oncol, 2017 May 12; 3(12). PMID: 28494073    Free PMC article.
Highly Cited.
AHNAK suppresses tumour proliferation and invasion by targeting multiple pathways in triple-negative breast cancer.
Bo Chen, Jin Wang, +7 authors, Xiaoming Xie.
J Exp Clin Cancer Res, 2017 May 13; 36(1). PMID: 28494797    Free PMC article.
RNA-Seq based genome-wide analysis reveals loss of inter-chromosomal regulation in breast cancer.
Jesús Espinal-Enríquez, Cristóbal Fresno, Guillermo Anda-Jáuregui, Enrique Hernández-Lemus.
Sci Rep, 2017 May 13; 7(1). PMID: 28496157    Free PMC article.
BAG-1 as a biomarker in early breast cancer prognosis: a systematic review with meta-analyses.
E S Papadakis, T Reeves, +3 authors, R I Cutress.
Br J Cancer, 2017 May 17; 116(12). PMID: 28510570    Free PMC article.
Systematic Review.
Immune signature of metastatic breast cancer: Identifying predictive markers of immunotherapy response.
Ji-Yeon Kim, Eunjin Lee, +5 authors, Yeon Hee Park.
Oncotarget, 2017 May 26; 8(29). PMID: 28537889    Free PMC article.
Interaction of glycosphingolipids GD3 and GD2 with growth factor receptors maintains breast cancer stem cell phenotype.
Yuh-Jin Liang, Chen-Yu Wang, +9 authors, John Yu.
Oncotarget, 2017 May 26; 8(29). PMID: 28537895    Free PMC article.
Targeting the Molecular Subtypes of Triple Negative Breast Cancer: Understanding the Diversity to Progress the Field.
Clinton Yam, Sendurai A Mani, Stacy L Moulder.
Oncologist, 2017 Jun 01; 22(9). PMID: 28559413    Free PMC article.
Review.
Clinical utility of gene-expression signatures in early stage breast cancer.
Maryann Kwa, Andreas Makris, Francisco J Esteva.
Nat Rev Clin Oncol, 2017 Jun 01; 14(10). PMID: 28561071
Highly Cited. Review.
CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to palbociclib.
Eric Raspé, Katia Coulonval, +14 authors, Pierre P Roger.
EMBO Mol Med, 2017 Jun 02; 9(8). PMID: 28566333    Free PMC article.
Targeting EphA2 impairs cell cycle progression and growth of basal-like/triple-negative breast cancers.
W Song, Y Hwang, +4 authors, D M Brantley-Sieders.
Oncogene, 2017 Jun 06; 36(40). PMID: 28581527    Free PMC article.
Therapeutic Potential of Matrix Metalloproteinase Inhibition in Breast Cancer.
Evette S Radisky, Maryam Raeeszadeh-Sarmazdeh, Derek C Radisky.
J Cell Biochem, 2017 Jun 07; 118(11). PMID: 28585723    Free PMC article.
Review.
Prediction of adjuvant chemotherapy response in triple negative breast cancer with discovery and targeted proteomics.
Angelo Gámez-Pozo, Lucía Trilla-Fuertes, +10 authors,