Journal Article
. 2009 Mar; 454(4):421-9.
doi: 10.1007/s00428-009-0749-3.

A European network for virtual microscopy--design, implementation and evaluation of performance

Mikael Lundin 1 Janusz Szymas  Ewert Linder  Hans Beck  Peter de Wilde  Han van Krieken  Marcial García Rojo  Ignacio Moreno  Aurelio Ariza  Sitki Tuzlali  Sergülen Dervişoğlu  Heikki Helin  Veli-Pekka Lehto  Johan Lundin  
  • PMID: 19280223
  •     11 References
  •     10 citations


Web-based virtual microscopy has enabled new applications within pathology. Here, we introduce and evaluate a network of academic servers, designed to maximize image accessibility to users from all regions of Europe. Whole-slide imaging was utilized to digitize the entire slide set (n = 154) for the slide seminars of the 21st European Congress of Pathology. The virtual slides were mirrored to five academic servers across Europe using a novel propagation method. Functionality was implemented that automatically selects the fastest server connection in order to optimize the slide-viewing speed ( Results show that during 6 months of monitoring the uptime of the network was 100%. The average viewing speed with the network was 3.1 Mbit/s, as compared to 1.9 Mbit/s using single servers. A good viewing speed (>2Mbit/s) was observed in 32 of 37 countries (86%), compared to 25 of 37 (68%) using single servers. Our study shows that implementing a virtual microscopy network spanning a large geographical area is technically feasible. By utilizing existing academic networks and cost-minimizing image compression, it is also economically feasible.

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