Journal Article
. 2009 May; 101(10):736-50.
doi: 10.1093/jnci/djp082.

Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer

Maggie C U Cheang 1 Stephen K Chia  David Voduc  Dongxia Gao  Samuel Leung  Jacqueline Snider  Mark Watson  Sherri Davies  Philip S Bernard  Joel S Parker  Charles M Perou  Matthew J Ellis  Torsten O Nielsen  
Affiliations
  • PMID: 19436038
  •     53 References
  •     732 citations

Abstract

Background: Gene expression profiling of breast cancer has identified two biologically distinct estrogen receptor (ER)-positive subtypes of breast cancer: luminal A and luminal B. Luminal B tumors have higher proliferation and poorer prognosis than luminal A tumors. In this study, we developed a clinically practical immunohistochemistry assay to distinguish luminal B from luminal A tumors and investigated its ability to separate tumors according to breast cancer recurrence-free and disease-specific survival.

Methods: Tumors from a cohort of 357 patients with invasive breast carcinomas were subtyped by gene expression profile. Hormone receptor status, HER2 status, and the Ki67 index (percentage of Ki67-positive cancer nuclei) were determined immunohistochemically. Receiver operating characteristic curves were used to determine the Ki67 cut point to distinguish luminal B from luminal A tumors. The prognostic value of the immunohistochemical assignment for breast cancer recurrence-free and disease-specific survival was investigated with an independent tissue microarray series of 4046 breast cancers by use of Kaplan-Meier curves and multivariable Cox regression.

Results: Gene expression profiling classified 101 (28%) of the 357 tumors as luminal A and 69 (19%) as luminal B. The best Ki67 index cut point to distinguish luminal B from luminal A tumors was 13.25%. In an independent cohort of 4046 patients with breast cancer, 2847 had hormone receptor-positive tumors. When HER2 immunohistochemistry and the Ki67 index were used to subtype these 2847 tumors, we classified 1530 (59%, 95% confidence interval [CI] = 57% to 61%) as luminal A, 846 (33%, 95% CI = 31% to 34%) as luminal B, and 222 (9%, 95% CI = 7% to 10%) as luminal-HER2 positive. Luminal B and luminal-HER2-positive breast cancers were statistically significantly associated with poor breast cancer recurrence-free and disease-specific survival in all adjuvant systemic treatment categories. Of particular relevance are women who received tamoxifen as their sole adjuvant systemic therapy, among whom the 10-year breast cancer-specific survival was 79% (95% CI = 76% to 83%) for luminal A, 64% (95% CI = 59% to 70%) for luminal B, and 57% (95% CI = 47% to 69%) for luminal-HER2 subtypes.

Conclusion: Expression of ER, progesterone receptor, and HER2 proteins and the Ki67 index appear to distinguish luminal A from luminal B breast cancer subtypes.

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Protein expression, survival and docetaxel benefit in node-positive breast cancer treated with adjuvant chemotherapy in the FNCLCC-PACS 01 randomized trial.
Jocelyne Jacquemier, Jean-Marie Boher, +12 authors, François Bertucci.
Breast Cancer Res, 2011 Nov 03; 13(6). PMID: 22044691    Free PMC article.
Altered expression of insulin receptor isoforms in breast cancer.
Jiaqi Huang, Chris Morehouse, +12 authors, Yihong Yao.
PLoS One, 2011 Nov 03; 6(10). PMID: 22046260    Free PMC article.
Ki-67: level of evidence and methodological considerations for its role in the clinical management of breast cancer: analytical and critical review.
Elisabeth Luporsi, Fabrice André, +22 authors, Jean-Pierre Bellocq.
Breast Cancer Res Treat, 2011 Nov 04; 132(3). PMID: 22048814    Free PMC article.
Highly Cited. Review.
Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment.
Peter A Fasching, Katharina Heusinger, +14 authors, David L Wachter.
BMC Cancer, 2011 Nov 16; 11. PMID: 22081974    Free PMC article.
Highly Cited.
Targeting abnormal DNA repair in therapy-resistant breast cancers.
Lisa A Tobin, Carine Robert, +7 authors, Feyruz V Rassool.
Mol Cancer Res, 2011 Nov 25; 10(1). PMID: 22112941    Free PMC article.
Invasive Breast Cancer: Recognition of Molecular Subtypes.
Johanna D Strehl, David L Wachter, +2 authors, Arndt Hartmann.
Breast Care (Basel), 2011 Dec 03; 6(4). PMID: 22135623    Free PMC article.
Practical implications of gene-expression-based assays for breast oncologists.
Aleix Prat, Matthew J Ellis, Charles M Perou.
Nat Rev Clin Oncol, 2011 Dec 07; 9(1). PMID: 22143140    Free PMC article.
Highly Cited. Review.
Triple-negative subtype predicts poor overall survival and high locoregional relapse in inflammatory breast cancer.
Jing Li, Ana M Gonzalez-Angulo, +12 authors, Thomas A Buchholz.
Oncologist, 2011 Dec 08; 16(12). PMID: 22147002    Free PMC article.
gef gene expression in MCF-7 breast cancer cells is associated with a better prognosis and induction of apoptosis by p53-mediated signaling pathway.
Houria Boulaiz, Pablo J Alvarez, +8 authors, Antonia Aránega.
Int J Mol Sci, 2011 Dec 17; 12(11). PMID: 22174609    Free PMC article.
Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).
Laura J Esserman, Donald A Berry, +32 authors, I-SPY 1 TRIAL Investigators.
Breast Cancer Res Treat, 2011 Dec 27; 132(3). PMID: 22198468    Free PMC article.
Highly Cited.
Luminal-B breast cancer and novel therapeutic targets.
Ben Tran, Philippe L Bedard.
Breast Cancer Res, 2012 Jan 06; 13(6). PMID: 22217398    Free PMC article.
Review.
Prognostic value of proliferation assay in the luminal, HER2-positive, and triple-negative biologic classes of breast cancer.
Mohammed A Aleskandarany, Andrew R Green, +5 authors, Emad A Rakha.
Breast Cancer Res, 2012 Jan 10; 14(1). PMID: 22225836    Free PMC article.
HER2 and TOP2A in high-risk early breast cancer patients treated with adjuvant epirubicin-based dose-dense sequential chemotherapy.
George Fountzilas, Christos Valavanis, +18 authors, Petroula Arapantoni.
J Transl Med, 2012 Jan 14; 10. PMID: 22240029    Free PMC article.
Expression of the androgen receptor and its correlation with molecular subtypes in 980 chinese breast cancer patients.
Ji-Ping Qi, You-Lin Yang, +11 authors, Ping Tang.
Breast Cancer (Auckl), 2012 Jan 20; 6. PMID: 22259247    Free PMC article.
A Comparative Analysis of Biomarker Expression and Molecular Subtypes of Pure Ductal Carcinoma In Situ and Invasive Breast Carcinoma by Image Analysis: Relationship of the Subtypes with Histologic Grade, Ki67, p53 Overexpression, and DNA Ploidy.
Venetia R Sarode, Jeong S Han, +2 authors, Roshni Rao.
Int J Breast Cancer, 2012 Feb 02; 2011. PMID: 22295212    Free PMC article.
Do we need biomarkers to predict the benefit of adding adjuvant taxanes for treatment of breast cancer?
José Pérez-García, Javier Cortés.
Breast Cancer Res, 2012 Feb 03; 14(1). PMID: 22297134    Free PMC article.
Gemcitabine and carboplatin for pretreated metastatic breast cancer: the predictive value of immunohistochemically defined subtypes.
Fabrizio Nelli, Luca Moscetti, +6 authors, Enzo Maria Ruggeri.
Int J Clin Oncol, 2012 Feb 22; 18(2). PMID: 22350024
Responsiveness of intrinsic subtypes to adjuvant anthracycline substitution in the NCIC.CTG MA.5 randomized trial.
Maggie C U Cheang, K David Voduc, +15 authors, Torsten O Nielsen.
Clin Cancer Res, 2012 Feb 22; 18(8). PMID: 22351696    Free PMC article.
Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer.
Roxana Schillaci, Pablo Guzmán, +10 authors, Patricia V Elizalde.
BMC Cancer, 2012 Feb 24; 12. PMID: 22356700    Free PMC article.
Proteomic analyses reveal high expression of decorin and endoplasmin (HSP90B1) are associated with breast cancer metastasis and decreased survival.
Thomas R Cawthorn, Juan C Moreno, +16 authors, Susan J Done.
PLoS One, 2012 Mar 01; 7(2). PMID: 22363530    Free PMC article.
Use of neoadjuvant data to design adjuvant endocrine therapy trials for breast cancer.
Rodrigo Goncalves, Cynthia Ma, +2 authors, Matthew James Ellis.
Nat Rev Clin Oncol, 2012 Mar 01; 9(4). PMID: 22371132    Free PMC article.
Review.
Correlations between diffusion-weighted imaging and breast cancer biomarkers.
Laura Martincich, Veronica Deantoni, +9 authors, Filippo Montemurro.
Eur Radiol, 2012 Mar 14; 22(7). PMID: 22411304
Agreement in risk prediction between the 21-gene recurrence score assay (Oncotype DX®) and the PAM50 breast cancer intrinsic Classifier™ in early-stage estrogen receptor-positive breast cancer.
Catherine M Kelly, Philip S Bernard, +7 authors, Lajos Pusztai.
Oncologist, 2012 Mar 16; 17(4). PMID: 22418568    Free PMC article.
CD8+ lymphocyte infiltration is an independent favorable prognostic indicator in basal-like breast cancer.
Shuzhen Liu, Jonathan Lachapelle, +3 authors, Torsten O Nielsen.
Breast Cancer Res, 2012 Mar 17; 14(2). PMID: 22420471    Free PMC article.
Highly Cited.
MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition.
Dai Horiuchi, Leonard Kusdra, +11 authors, Andrei Goga.
J Exp Med, 2012 Mar 21; 209(4). PMID: 22430491    Free PMC article.
Highly Cited.
Germline copy number variants are not associated with globally acquired copy number changes in familial breast tumours.
Logan C Walker, Lutz Krause, +2 authors, Nic Waddell.
Breast Cancer Res Treat, 2012 Mar 22; 134(3). PMID: 22434526    Free PMC article.
Peritumoral vascular invasion and NHERF1 expression define an immunophenotype of grade 2 invasive breast cancer associated with poor prognosis.
Andrea Malfettone, Concetta Saponaro, +2 authors, Annita Mangia.
BMC Cancer, 2012 Mar 24; 12. PMID: 22439624    Free PMC article.
Membrane progesterone receptor alpha as a potential prognostic biomarker for breast cancer survival: a retrospective study.
Mingxuan Xie, Xiangzhu Zhu, +6 authors, Shaojin You.
PLoS One, 2012 Apr 13; 7(4). PMID: 22496908    Free PMC article.
Concordance among gene expression-based predictors for ER-positive breast cancer treated with adjuvant tamoxifen.
A Prat, J S Parker, +9 authors, C M Perou.
Ann Oncol, 2012 Apr 26; 23(11). PMID: 22532584    Free PMC article.
Aurora kinase A outperforms Ki67 as a prognostic marker in ER-positive breast cancer.
H R Ali, S-J Dawson, +3 authors, C Caldas.
Br J Cancer, 2012 Apr 28; 106(11). PMID: 22538974    Free PMC article.
Pre-treatment hormonal receptor status and Ki67 index predict pathologic complete response to neoadjuvant trastuzumab/taxanes but not disease-free survival in HER2-positive breast cancer patients.
Guo-Chun Zhang, Xue-Ke Qian, +6 authors, Ning Liao.
Med Oncol, 2012 May 02; 29(5). PMID: 22547076
Prognostic and predictive value of TP53 mutations in node-positive breast cancer patients treated with anthracycline- or anthracycline/taxane-based adjuvant therapy: results from the BIG 02-98 phase III trial.
Lynnette Fernández-Cuesta, Catherine Oakman, +14 authors, Magali Olivier.
Breast Cancer Res, 2012 May 04; 14(3). PMID: 22551440    Free PMC article.
Generation and analysis of a mouse intestinal metatranscriptome through Illumina based RNA-sequencing.
Xuejian Xiong, Daniel N Frank, +8 authors, John Parkinson.
PLoS One, 2012 May 05; 7(4). PMID: 22558305    Free PMC article.
Poor-prognosis estrogen receptor- positive disease: present and future clinical solutions.
Per E Lønning.
Ther Adv Med Oncol, 2012 May 17; 4(3). PMID: 22590486    Free PMC article.
Distribution, clinicopathologic features and survival of breast cancer subtypes in Southern China.
Cong Xue, Xi Wang, +7 authors, Zhongyu Yuan.
Cancer Sci, 2012 May 26; 103(9). PMID: 22625227    Free PMC article.
Behaviour of breast cancer molecular subtypes through tumour progression.
Carlos A Castaneda, Eva Andrés, +3 authors, Eva Ciruelos.
Clin Transl Oncol, 2012 May 29; 14(6). PMID: 22634538
Biological characterization and selection criteria of adjuvant chemotherapy for early breast cancer: experience from the Italian observational NEMESI study.
Matteo Clavarezza, Giorgio Mustacchi, +13 authors, Marco Venturini.
BMC Cancer, 2012 Jun 08; 12. PMID: 22672524    Free PMC article.
Differential response of immunohistochemically defined breast cancer subtypes to anthracycline-based adjuvant chemotherapy with or without paclitaxel.
George Fountzilas, Urania Dafni, +18 authors, Meletios A Dimopoulos.
PLoS One, 2012 Jun 09; 7(6). PMID: 22679488    Free PMC article.
Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance.
Justin M Balko, Rebecca S Cook, +15 authors, Carlos L Arteaga.
Nat Med, 2012 Jun 12; 18(7). PMID: 22683778    Free PMC article.
Highly Cited.
Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression.
Todd P Knutson, Andrea R Daniel, +4 authors, Carol A Lange.
Breast Cancer Res, 2012 Jun 16; 14(3). PMID: 22697792    Free PMC article.
AKT-aro and HER2-aro, models for de novo resistance to aromatase inhibitors; molecular characterization and inhibitor response studies.
Cynthie Wong, Xin Wang, +2 authors, Shiuan Chen.
Breast Cancer Res Treat, 2012 Jun 19; 134(2). PMID: 22706627    Free PMC article.
A 50-gene intrinsic subtype classifier for prognosis and prediction of benefit from adjuvant tamoxifen.
Stephen K Chia, Vivien H Bramwell, +12 authors, Torsten O Nielsen.
Clin Cancer Res, 2012 Jun 20; 18(16). PMID: 22711706    Free PMC article.
Highly Cited.
Tumour biomarker expression relative to age and molecular subtypes of invasive breast cancer.
D H Morrison, D Rahardja, +2 authors, V R Sarode.
Br J Cancer, 2012 Jun 21; 107(2). PMID: 22713661    Free PMC article.
Stromal genes add prognostic information to proliferation and histoclinical markers: a basis for the next generation of breast cancer gene signatures.
Dwain Mefford, Joel Mefford.
PLoS One, 2012 Jun 22; 7(6). PMID: 22719844    Free PMC article.
Amplified loci on chromosomes 8 and 17 predict early relapse in ER-positive breast cancers.
Erhan Bilal, Kristen Vassallo, +8 authors, Shridar Ganesan.
PLoS One, 2012 Jun 22; 7(6). PMID: 22719901    Free PMC article.
Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.
Karolina Holm, Dorthe Grabau, +13 authors, Markus Ringnér.
Mol Oncol, 2012 Jul 07; 6(5). PMID: 22766277    Free PMC article.
High-risk estrogen-receptor-positive breast cancer: identification and implications for therapy.
Rosemary L Balleine, Nicholas R Wilcken.
Mol Diagn Ther, 2012 Jul 21; 16(4). PMID: 22812573
Review.
Can predictive biomarkers in breast cancer guide adjuvant endocrine therapy?
Karin Beelen, Wilbert Zwart, Sabine C Linn.
Nat Rev Clin Oncol, 2012 Jul 25; 9(9). PMID: 22825374
Review.
Luminal A and luminal B (HER2 negative) subtypes of breast cancer consist of a mixture of tumors with different genotype.
Masumi Yanagawa, Kenzo Ikemot, +6 authors, Kohsuke Sasaki.
BMC Res Notes, 2012 Jul 27; 5. PMID: 22830453    Free PMC article.
The gene expression landscape of breast cancer is shaped by tumor protein p53 status and epithelial-mesenchymal transition.
Erik Fredlund, Johan Staaf, +3 authors, Markus Ringnér.
Breast Cancer Res, 2012 Jul 31; 14(4). PMID: 22839103    Free PMC article.
Moderate immunohistochemical expression of HER-2 (2+) without HER-2 gene amplification is a negative prognostic factor in early breast cancer.
Valentina Rossi, Ivana Sarotto, +9 authors, Filippo Montemurro.
Oncologist, 2012 Sep 07; 17(11). PMID: 22951668    Free PMC article.
The molecular profile of luminal B breast cancer.
Chad J Creighton.
Biologics, 2012 Sep 08; 6. PMID: 22956860    Free PMC article.
Ki-67 as a prognostic marker according to breast cancer subtype and a predictor of recurrence time in primary breast cancer.
Reiki Nishimura, Tomofumi Osako, +3 authors, Nobuyuki Arima.
Exp Ther Med, 2010 Sep 01; 1(5). PMID: 22993598    Free PMC article.
EndoPredict improves the prognostic classification derived from common clinical guidelines in ER-positive, HER2-negative early breast cancer.
P Dubsky, M Filipits, +17 authors, Austrian Breast and Colorectal Cancer Study Group (ABCSG).
Ann Oncol, 2012 Oct 05; 24(3). PMID: 23035151    Free PMC article.
Prognostic value of the hDMP1-ARF-Hdm2-p53 pathway in breast cancer.
D Maglic, S Zhu, +7 authors, K Inoue.
Oncogene, 2012 Oct 10; 32(35). PMID: 23045280    Free PMC article.
Long-term outcome of neoadjuvant systemic therapy for locally advanced breast cancer in routine clinical practice.
Domenico Angelucci, Nicola Tinari, +13 authors, Clara Natoli.
J Cancer Res Clin Oncol, 2012 Oct 12; 139(2). PMID: 23052698    Free PMC article.
[Translational research and diagnostics for breast cancer].
H H Kreipe.
Pathologe, 2012 Oct 16; 33 Suppl 2. PMID: 23064514
Review.
Topoisomerase II alpha gene amplification is a favorable prognostic factor in patients with HER2-positive metastatic breast cancer treated with trastuzumab.
George Fountzilas, Christos Christodoulou, +12 authors, Konstantine T Kalogeras.
J Transl Med, 2012 Oct 25; 10. PMID: 23092535    Free PMC article.
Prognostic interaction between expression of p53 and estrogen receptor in patients with node-negative breast cancer: results from IBCSG Trials VIII and IX.
Alan S Coates, Ewan K A Millar, +10 authors, Robert L Sutherland.
Breast Cancer Res, 2012 Nov 07; 14(6). PMID: 23127292    Free PMC article.
A pure invasive cribriform carcinoma of the breast with bone metastasis if untreated for thirteen years: a case report and literature review.
Wei Zhang, Zhichun Lin, +2 authors, Yun Niu.
World J Surg Oncol, 2012 Nov 22; 10. PMID: 23167837    Free PMC article.
Review.
Expression of MHC Class I on breast cancer cells correlates inversely with HER2 expression.
Masayuki Inoue, Kousaku Mimura, +13 authors, Koji Kono.
Oncoimmunology, 2012 Nov 22; 1(7). PMID: 23170258    Free PMC article.
Association between body mass index and breast cancer intrinsic subtypes in Japanese women.
Kosei Kimura, Satoru Tanaka, +4 authors, Kazuhisa Uchiyama.
Exp Ther Med, 2012 Nov 28; 4(3). PMID: 23181105    Free PMC article.
Prognostic significance of progesterone receptor-positive tumor cells within immunohistochemically defined luminal A breast cancer.
Aleix Prat, Maggie Chon U Cheang, +8 authors, Charles M Perou.
J Clin Oncol, 2012 Dec 13; 31(2). PMID: 23233704    Free PMC article.
Highly Cited.
Role of microRNAs in breast cancer.
Ramesh Singh, Yin-Yuan Mo.
Cancer Biol Ther, 2013 Jan 08; 14(3). PMID: 23291983    Free PMC article.
Review.
Analysis of the potent prognostic factors in luminal-type breast cancer.
Han-Sung Kim, Inseok Park, +7 authors, Young-Duck Kim.
J Breast Cancer, 2013 Jan 25; 15(4). PMID: 23346168    Free PMC article.
Expression profiling of 21 biomolecules in locally advanced nasopharyngeal carcinomas of Caucasian patients.
Dimitrios Krikelis, Mattheos Bobos, +7 authors, George Fountzilas.
BMC Clin Pathol, 2013 Jan 31; 13. PMID: 23360534    Free PMC article.
Significance analysis of prognostic signatures.
Andrew H Beck, Nicholas W Knoblauch, +7 authors, Benjamin Haibe-Kains.
PLoS Comput Biol, 2013 Feb 01; 9(1). PMID: 23365551    Free PMC article.
The maximum standardized uptake value of 18 F-FDG PET scan to determine prognosis of hormone-receptor positive metastatic breast cancer.
Jian Zhang, Zhen Jia, +7 authors, Xi-Chun Hu.
BMC Cancer, 2013 Feb 02; 13. PMID: 23368410    Free PMC article.
A simple immunohistochemical panel comprising 2 conventional markers, Ki67 and p53, is a powerful tool for predicting patient outcome in luminal-type breast cancer.
Takayuki Kobayashi, Keiichi Iwaya, +4 authors, Osamu Matsubara.
BMC Clin Pathol, 2013 Feb 07; 13. PMID: 23384409    Free PMC article.
A new genome-driven integrated classification of breast cancer and its implications.
Sarah-Jane Dawson, Oscar M Rueda, Samuel Aparicio, Carlos Caldas.
EMBO J, 2013 Feb 12; 32(5). PMID: 23395906    Free PMC article.
Highly Cited. Review.
[Molecular classification of breast cancer in Morocco].
Abbass Fouad, Akasbi Yousra, +3 authors, Bennis Sanae.
Pan Afr Med J, 2013 Feb 12; 13. PMID: 23396646    Free PMC article.
Low expression of Beclin 1 and elevated expression of HIF-1α refine distant metastasis risk and predict poor prognosis of ER-positive, HER2-negative breast cancer.
Min Dong, Xiang-bo Wan, +12 authors, Xiang Yuan Wu.
Med Oncol, 2013 Feb 15; 30(1). PMID: 23408367
Invasive cribriform carcinoma in a Chinese population: comparison with low-grade invasive ductal carcinoma-not otherwise specified.
Wei Zhang, Tongxian Zhang, +6 authors, Yun Niu.
Int J Clin Exp Pathol, 2013 Feb 16; 6(3). PMID: 23412348    Free PMC article.
A dual-regulated oncolytic adenovirus expressing interleukin-24 sensitizes melanoma cells to temozolomide via the induction of apoptosis.
Guan Jiang, Ai-Jun Jiang, +3 authors, Jun-Nian Zheng.
Tumour Biol, 2013 Feb 23; 34(2). PMID: 23430584
Epirubicin and docetaxel as neoadjuvant treatment of hormone receptor positive, HER-2 negative breast cancer: findings from two successive phase II studies.
Alessandro Tuzi, Davide Lombardi, +5 authors, Andrea Veronesi.
Radiol Oncol, 2013 Mar 02; 47(1). PMID: 23450278    Free PMC article.
ER, PR, HER2, Ki-67 and CK5 in Early and Late Relapsing Breast Cancer-Reduced CK5 Expression in Metastases.
Kristiina Joensuu, Marjut Leidenius, +3 authors, Päivi Heikkilä.
Breast Cancer (Auckl), 2013 Mar 22; 7. PMID: 23514931    Free PMC article.
Long-term prognostic performance of Ki67 rate in early stage, pT1-pT2, pN0, invasive breast carcinoma.
Fabien Reyal, David Hajage, +14 authors, Xavier Sastre-Garau.
PLoS One, 2013 Mar 26; 8(3). PMID: 23526930    Free PMC article.
Evaluation of the prognostic role of centromere 17 gain and HER2/topoisomerase II alpha gene status and protein expression in patients with breast cancer treated with anthracycline-containing adjuvant chemotherapy: pooled analysis of two Hellenic Cooperative Oncology Group (HeCOG) phase III trials.
George Fountzilas, Urania Dafni, +21 authors, Meletios A Dimopoulos.
BMC Cancer, 2013 Mar 30; 13. PMID: 23537287    Free PMC article.
Tailoring treatment for ductal intraepithelial neoplasia of the breast according to Ki-67 and molecular phenotype.
M Lazzeroni, A Guerrieri-Gonzaga, +12 authors, G Pruneri.
Br J Cancer, 2013 Apr 13; 108(8). PMID: 23579208    Free PMC article.
Efficacy of exemestane in korean patients with metastatic breast cancer after failure of nonsteroidal aromatase inhibitors.
June Koo Lee, Seock-Ah Im, +12 authors, Dong-Young Noh.
J Breast Cancer, 2013 Apr 18; 16(1). PMID: 23593084    Free PMC article.
Molecular subtypes of breast cancer: metabolic correlation with ¹⁸F-FDG PET/CT.
Ana María García Vicente, Ángel Soriano Castrejón, +6 authors, Ana González Ageitos.
Eur J Nucl Med Mol Imaging, 2013 May 02; 40(9). PMID: 23632960
Diffusion-weighted MRI in pretreatment prediction of response to neoadjuvant chemotherapy in patients with breast cancer.
Raphael Richard, Isabelle Thomassin, +7 authors, Cedric de Bazelaire.
Eur Radiol, 2013 May 09; 23(9). PMID: 23652844
Ki-67 is a prognostic parameter in breast cancer patients: results of a large population-based cohort of a cancer registry.
E C Inwald, M Klinkhammer-Schalke, +4 authors, O Ortmann.
Breast Cancer Res Treat, 2013 May 16; 139(2). PMID: 23674192    Free PMC article.
Highly Cited.
Illuminating luminal B: QSOX1 as a subtype-specific biomarker.
Padmalaya Das, Gabrielle M Siegers, Lynne-Marie Postovit.
Breast Cancer Res, 2013 May 18; 15(3). PMID: 23680167    Free PMC article.
Unique clinicopathological features of metaplastic breast carcinoma compared with invasive ductal carcinoma and poor prognostic indicators.
Yanni Song, Xiaolong Liu, +10 authors, Da Pang.
World J Surg Oncol, 2013 Jun 07; 11. PMID: 23738706    Free PMC article.
Somatic mutation profiling and associations with prognosis and trastuzumab benefit in early breast cancer.
Sherene Loi, Stefan Michiels, +8 authors, Christos Sotiriou.
J Natl Cancer Inst, 2013 Jun 07; 105(13). PMID: 23739063    Free PMC article.
Basal cytokeratin as a potential marker of low risk of invasion in ductal carcinoma in situ.
Fernando N Aguiar, Henrique N Mendes, +2 authors, Filomena M Carvalho.
Clinics (Sao Paulo), 2013 Jun 20; 68(5). PMID: 23778411    Free PMC article.
Influence of body mass index on clinicopathological factors including estrogen receptor, progesterone receptor, and Ki67 expression levels in breast cancers.
Ayako Yanai, Yoshimasa Miyagawa, +9 authors, Yasuo Miyoshi.
Int J Clin Oncol, 2013 Jul 04; 19(3). PMID: 23821234
Response prediction to neoadjuvant chemotherapy: comparison between pre-therapeutic gene expression profiles and in vitro chemosensitivity assay.
Christian F Singer, Florian Klinglmüller, +8 authors, Martin Bilban.
PLoS One, 2013 Jul 05; 8(6). PMID: 23826101    Free PMC article.
Breast cancer subtyping by immunohistochemistry and histological grade outperforms breast cancer intrinsic subtypes in predicting neoadjuvant chemotherapy response.
E H Lips, L Mulder, +5 authors, J Wesseling.
Breast Cancer Res Treat, 2013 Jul 06; 140(1). PMID: 23828499    Free PMC article.
Immunohistochemical evaluation of human epidermal growth factor receptor 2 and estrogen and progesterone receptors in invasive breast cancer in women.
Anna M Badowska-Kozakiewicz, Maria Sobol, Janusz Patera, Wojciech Kozłowski.
Arch Med Sci, 2013 Jul 13; 9(3). PMID: 23847668    Free PMC article.
Glycoprotein non-metastatic b (GPNMB): A metastatic mediator and emerging therapeutic target in cancer.
Gordana Maric, April An Rose, Matthew G Annis, Peter M Siegel.
Onco Targets Ther, 2013 Jul 23; 6. PMID: 23874106    Free PMC article.
Relative and disease-free survival for breast cancer in relation to subtype: a population-based study.
Pamela Minicozzi, Francesca Bella, +10 authors, Milena Sant.
J Cancer Res Clin Oncol, 2013 Jul 31; 139(9). PMID: 23892409
The genomic map of breast cancer: which roads lead to better targeted therapies?
Justin M Balko, Thomas P Stricker, Carlos L Arteaga.
Breast Cancer Res, 2013 Aug 03; 15(4). PMID: 23905624    Free PMC article.
Review.
Assignment of tumor subtype by genomic testing and pathologic-based approximations: implications on patient's management and therapy selection.
A Romero, A Prat, +9 authors, M Martín.
Clin Transl Oncol, 2013 Aug 03; 16(4). PMID: 23907291
Steroid receptor RNA activator protein (SRAP) expression as a prognostic factor in ER+ human breast tumors.
Yi Yan, Carla C Penner, +8 authors, Etienne Leygue.
J Cancer Res Clin Oncol, 2013 Aug 03; 139(10). PMID: 23907597
Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013.
A Goldhirsch, E P Winer, +5 authors, Panel members.
Ann Oncol, 2013 Aug 07; 24(9). PMID: 23917950    Free PMC article.
Highly Cited.
Imaging features of sporadic breast cancer in women under 40 years old: 97 cases.
Bénédicte Bullier, Gaétan MacGrogan, +4 authors, Martine Boisserie-Lacroix.
Eur Radiol, 2013 Aug 07; 23(12). PMID: 23918218
Prognostic significance of ESR1 gene amplification, mRNA/protein expression and functional profiles in high-risk early breast cancer: a translational study of the Hellenic Cooperative Oncology Group (HeCOG).
George Pentheroudakis, Vassiliki Kotoula, +19 authors, George Fountzilas.
PLoS One, 2013 Aug 08; 8(7). PMID: 23923010    Free PMC article.
[Gene expression analysis in breast cancer. A new diagnostic tool in pathology].
C Denkert.
Pathologe, 2013 Aug 13; 34(5). PMID: 23934410
Review.
Survival Analysis Based on Clinicopathological Data from a Single Institution: Chemotherapy Intensity Would Be Enhanced in Patients with Positive Hormone Receptors and Positive HER2 in China Who Cannot Afford the Target Therapy.
Jianyi Li, Shi Jia, +3 authors, Rui Tian.
ISRN Oncol, 2013 Aug 29; 2013. PMID: 23984097    Free PMC article.
Luminal breast cancer cell lines overexpressing ZNF703 are resistant to tamoxifen through activation of Akt/mTOR signaling.
Xi Zhang, Xin Mu, +4 authors, Kunwei Shen.
PLoS One, 2013 Aug 31; 8(8). PMID: 23991038    Free PMC article.
Molecular and cellular heterogeneity in breast cancer: challenges for personalized medicine.
Ashley G Rivenbark, Siobhan M O'Connor, William B Coleman.
Am J Pathol, 2013 Sep 03; 183(4). PMID: 23993780    Free PMC article.
Review.
Value of pre-treatment biomarkers in prediction of response to neoadjuvant endocrine therapy for hormone receptor-positive postmenopausal breast cancer.
Min Ying, Yingjian He, +7 authors, Tao Ouyang.
Chin J Cancer Res, 2013 Sep 03; 25(4). PMID: 23997526    Free PMC article.
Elevated expression of tumor miR-222 in pancreatic cancer is associated with Ki67 and poor prognosis.
ChongLek Lee, Hang He, +5 authors, Deliang Fu.
Med Oncol, 2013 Sep 13; 30(4). PMID: 24026657
Pan-cancer patterns of somatic copy number alteration.
Travis I Zack, Stephen E Schumacher, +15 authors, Rameen Beroukhim.
Nat Genet, 2013 Sep 28; 45(10). PMID: 24071852    Free PMC article.
Highly Cited.
Lymph node involvement in immunohistochemistry-based molecular classifications of breast cancer.
Nicholas K Howland, Teryn D Driver, +5 authors, Celia Chao.
J Surg Res, 2013 Oct 08; 185(2). PMID: 24095025    Free PMC article.
18F-FDG uptake in breast cancer correlates with immunohistochemically defined subtypes.
Hye Ryoung Koo, Jeong Seon Park, +9 authors, Woo Kyung Moon.
Eur Radiol, 2013 Oct 08; 24(3). PMID: 24097303
Tumor secretion of CCL22 activates intratumoral Treg infiltration and is independent prognostic predictor of breast cancer.
Ya-Qing Li, Fang-Fang Liu, +3 authors, Li Fu.
PLoS One, 2013 Oct 15; 8(10). PMID: 24124553    Free PMC article.
Pattern of recurrence of early breast cancer is different according to intrinsic subtype and proliferation index.
Nuria Ribelles, Lidia Perez-Villa, +11 authors, Emilio Alba.
Breast Cancer Res, 2013 Oct 24; 15(5). PMID: 24148581    Free PMC article.
Prognostic value of the nodal ratio and ki-67 expression in breast cancer patients treated with postmastectomy radiotherapy.
Tae Ryool Koo, Keun Yong Eom, +5 authors, In Ah Kim.
J Breast Cancer, 2013 Oct 25; 16(3). PMID: 24155756    Free PMC article.
High expression of ZNF703 independent of amplification indicates worse prognosis in patients with luminal B breast cancer.
Inga Reynisdottir, Adalgeir Arason, +14 authors, Rosa Bjork Barkardottir.
Cancer Med, 2013 Oct 25; 2(4). PMID: 24156016    Free PMC article.
Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes.
Aleix Prat, Olga Karginova, +8 authors, Charles M Perou.
Breast Cancer Res Treat, 2013 Oct 29; 142(2). PMID: 24162158    Free PMC article.
Highly Cited.
Competing risks analysis in mortality estimation for breast cancer patients from independent risk groups.
Shengfan Zhang, Julie S Ivy, +2 authors, Bonnie C Yankaskas.
Health Care Manag Sci, 2013 Nov 19; 17(3). PMID: 24242701
Prognostic relevance at 5 years of the early monitoring of neoadjuvant chemotherapy using (18)F-FDG PET in luminal HER2-negative breast cancer.
Olivier Humbert, Alina Berriolo-Riedinger, +9 authors, François Brunotte.
Eur J Nucl Med Mol Imaging, 2013 Nov 22; 41(3). PMID: 24258007
St Gallen molecular subtypes in primary breast cancer and matched lymph node metastases--aspects on distribution and prognosis for patients with luminal A tumours: results from a prospective randomised trial.
Anna-Karin Falck, Mårten Fernö, Pär-Ola Bendahl, Lisa Rydén.
BMC Cancer, 2013 Nov 28; 13. PMID: 24274821    Free PMC article.
Reinventing diagnostics for personalized therapy in oncology.
Diponkar Banerjee.
Cancers (Basel), 2010 Jan 01; 2(2). PMID: 24281107    Free PMC article.
Are breast cancer molecular classes predictive of survival in patients with long follow-up?
Danae Pracella, Serena Bonin, +4 authors, Giorgio Stanta.
Dis Markers, 2013 Nov 30; 35(6). PMID: 24288429    Free PMC article.
Progesterone receptor expression is an independent prognostic variable in early breast cancer: a population-based study.
C A Purdie, P Quinlan, +4 authors, A M Thompson.
Br J Cancer, 2013 Dec 05; 110(3). PMID: 24300977    Free PMC article.
A collaborative study of the etiology of breast cancer subtypes in African American women: the AMBER consortium.
Julie R Palmer, Christine B Ambrosone, Andrew F Olshan.
Cancer Causes Control, 2013 Dec 18; 25(3). PMID: 24343304    Free PMC article.
Semi-automated evaluation of Ki-67 index in invasive ductal carcinoma of the breast.
Cristian Suciu, Anca Muresan, +3 authors, Marius Raica.
Oncol Lett, 2013 Dec 19; 7(1). PMID: 24348830    Free PMC article.
Clinicopathological features and prognosis of pregnancy associated breast cancer - a matched case control study.
Lilla Madaras, Kristóf Attila Kovács, +7 authors, Janina Kulka.
Pathol Oncol Res, 2013 Dec 21; 20(3). PMID: 24357159
Differential impact of the expression of the androgen receptor by age in estrogen receptor-positive breast cancer.
Eriko Tokunaga, Yuichi Hisamatsu, +10 authors, Yoshihiko Maehara.
Cancer Med, 2014 Jan 10; 2(6). PMID: 24403250    Free PMC article.
[Determination of proliferation in breast cancer by immunohistochemical detection of Ki-67].
M Christgen, W Winkens, H H Kreipe.
Pathologe, 2014 Jan 15; 35(1). PMID: 24414612
Expression of Immunohistochemical Markers before and after Neoadjuvant Chemotherapy in Breast Carcinoma, and Their Use as Predictors of Response.
Ho-Chang Lee, Hyoungsuk Ko, +5 authors, In Ae Park.
J Breast Cancer, 2014 Jan 24; 16(4). PMID: 24454461    Free PMC article.
Trastuzumab or lapatinib with standard chemotherapy for HER2-positive breast cancer: results from the GEICAM/2006-14 trial.
E Alba, J Albanell, +12 authors, A Lluch.
Br J Cancer, 2014 Jan 25; 110(5). PMID: 24457911    Free PMC article.
High levels of BCOX1 expression are associated with poor prognosis in patients with invasive ductal carcinomas of the breast.
Tong Liu, Xian-Yu Zhang, +7 authors, Da Pang.
PLoS One, 2014 Feb 04; 9(1). PMID: 24489812    Free PMC article.
Outcome disparities in African American women with triple negative breast cancer: a comparison of epidemiological and molecular factors between African American and Caucasian women with triple negative breast cancer.
Lori A Sturtz, Jen Melley, +2 authors, Rachel E Ellsworth.
BMC Cancer, 2014 Feb 06; 14. PMID: 24495414    Free PMC article.
Prognostic value of Ki-67 in breast cancer patients with positive axillary lymph nodes: a retrospective cohort study.
Feng-yan Li, San-gang Wu, +5 authors, Zhen-yu He.
PLoS One, 2014 Feb 06; 9(2). PMID: 24498305    Free PMC article.
Targeted biomarker profiling of matched primary and metastatic estrogen receptor positive breast cancers.
Erica B Schleifman, Rupal Desai, +13 authors, Mark R Lackner.
PLoS One, 2014 Feb 13; 9(2). PMID: 24520381    Free PMC article.
Long-term outcome of neoadjuvant endocrine therapy with aromatase inhibitors in elderly women with hormone receptor-positive breast cancer.
Antonino Grassadonia, Marta Di Nicola, +14 authors, Ettore Cianchetti.
Ann Surg Oncol, 2014 Feb 14; 21(5). PMID: 24522992    Free PMC article.
Genomic profiling in luminal breast cancer.
Oleg Gluz, Daniel Hofmann, +3 authors, Nadia Harbeck.
Breast Care (Basel), 2014 Feb 20; 8(6). PMID: 24550749    Free PMC article.
Review.
Expression of B7-H3, a potential factor of tumor immune evasion in combination with the number of regulatory T cells, affects against recurrence-free survival in breast cancer patients.
N Maeda, K Yoshimura, +13 authors, M Oka.
Ann Surg Oncol, 2014 Feb 25; 21 Suppl 4. PMID: 24562936    Free PMC article.
Relationship of CK8/18 expression pattern to breast cancer immunohistochemical subtyping in Egyptian patients.
Hayam A Aiad, Rehab M Samaka, +3 authors, Islam M Miligy.
Ecancermedicalscience, 2014 Mar 08; 8. PMID: 24605136    Free PMC article.
Deregulation of base excision repair gene expression and enhanced proliferation in head and neck squamous cell carcinoma.
Ishrat Mahjabeen, Kashif Ali, Xiaofeng Zhou, Mahmood Akhtar Kayani.
Tumour Biol, 2014 Mar 14; 35(6). PMID: 24622884
Baseline staging tests based on molecular subtype is necessary for newly diagnosed breast cancer.
Xuesong Chen, Lichun Sun, +8 authors, Xiaoqun Dong.
J Exp Clin Cancer Res, 2014 Mar 19; 33. PMID: 24628817    Free PMC article.
Multi-level gene expression signatures, but not binary, outperform Ki67 for the long term prognostication of breast cancer patients.
Nicholas P Tobin, Linda S Lindström, +3 authors, Kristian Wennmalm.
Mol Oncol, 2014 Mar 19; 8(3). PMID: 24630985    Free PMC article.
A microRNA signature associated with early recurrence in breast cancer.
Luis G Pérez-Rivas, José M Jerez, +9 authors, José Lozano.
PLoS One, 2014 Mar 19; 9(3). PMID: 24632820    Free PMC article.
Differential expression of the insulin-like growth factor receptor among early breast cancer subtypes.
Giannis Mountzios, Dimitra Aivazi, +14 authors, George Fountzilas.
PLoS One, 2014 Mar 19; 9(3). PMID: 24637962    Free PMC article.
Quantum dot-based immunofluorescent imaging of Ki67 and identification of prognostic value in HER2-positive (non-luminal) breast cancer.
Jin-Zhong Sun, Chuang Chen, +3 authors, Sheng-Rong Sun.
Int J Nanomedicine, 2014 Mar 22; 9. PMID: 24648732    Free PMC article.
Estrogen receptor-positive breast cancer molecular signatures and therapeutic potentials (Review).
Mei Hong Zhang, Hong Tao Man, +2 authors, Shi Liang Ma.
Biomed Rep, 2014 Mar 22; 2(1). PMID: 24649067    Free PMC article.
Collagen gel droplet-embedded culture-drug sensitivity test and Ki67 expression in estrogen receptor-positive and HER2-negative breast cancer.
Katsunori Tozuka, Jun Horiguchi, +7 authors, Izumi Takeyoshi.
Mol Clin Oncol, 2013 Jan 01; 1(1). PMID: 24649129    Free PMC article.
Joint detection of multiple immunohistochemical indices and clinical significance in breast cancer.
En-Qi Qiao, Minghua Ji, +9 authors, Ji-Hai Tang.
Mol Clin Oncol, 2014 Mar 22; 1(4). PMID: 24649232    Free PMC article.
Expression of neuroendocrine markers in different molecular subtypes of breast carcinoma.
David L Wachter, Arndt Hartmann, +4 authors, Abbas Agaimy.
Biomed Res Int, 2014 Apr 05; 2014. PMID: 24701575    Free PMC article.
Potent anti-tumour activity of a novel conditionally replicating adenovirus for melanoma via inhibition of migration and invasion.
G Jiang, C-S Yang, +4 authors, Y-Q Liu.
Br J Cancer, 2014 Apr 10; 110(10). PMID: 24714752    Free PMC article.
Invasive breast carcinomas of no special type with osteoclast-like giant cells frequently have a luminal phenotype.
Shuling Zhou, Lin Yu, +2 authors, Wentao Yang.
Virchows Arch, 2014 Apr 15; 464(6). PMID: 24728734
Changes in aldehyde dehydrogenase-1 expression during neoadjuvant chemotherapy predict outcome in locally advanced breast cancer.
Muhammad Alamgeer, Vinod Ganju, +8 authors, D Neil Watkins.
Breast Cancer Res, 2014 Apr 26; 16(2). PMID: 24762066    Free PMC article.
Levels of lymphocyte subsets in peripheral blood prior treatment are associated with aggressive breast cancer phenotypes or subtypes.
Yijun Jia, Lei Xu, +4 authors, Yunshu Lu.
Med Oncol, 2014 May 07; 31(6). PMID: 24798876
Different methods of pretreatment Ki-67 labeling index evaluation in core biopsies of breast cancer patients treated with neoadjuvant chemotherapy and their relation to response to therapy.
András Vörös, Erika Csörgő, +5 authors, Gábor Cserni.
Pathol Oncol Res, 2014 May 27; 21(1). PMID: 24859973
Prolactin-induced protein is required for cell cycle progression in breast cancer.
Ali Naderi, Marion Vanneste.
Neoplasia, 2014 May 28; 16(4). PMID: 24862759    Free PMC article.
Relationship between chemotherapy and prognosis in different subtypes of node-negative breast cancer.
Xia Liu, Yong Guan, +5 authors, Yun Niu.
Tumour Biol, 2014 May 28; 35(9). PMID: 24863944
The mTOR inhibitor rapamycin synergizes with a fatty acid synthase inhibitor to induce cytotoxicity in ER/HER2-positive breast cancer cells.
Chen Yan, Huang Wei, +4 authors, Han Sheng.
PLoS One, 2014 May 29; 9(5). PMID: 24866893    Free PMC article.
Current breast cancer proliferative markers correlate variably based on decoupled duration of cell cycle phases.
Lik Hang Lee, Hua Yang, Gilbert Bigras.
Sci Rep, 2014 May 31; 4. PMID: 24874299    Free PMC article.
Molecular classification of breast cancer.
Darina Vuong, Peter T Simpson, +2 authors, Sunil R Lakhani.
Virchows Arch, 2014 Jun 01; 465(1). PMID: 24878755
Lin28B expression correlates with aggressive clinicopathological characteristics in breast invasive ductal carcinoma.
Ruilian Xie, Yanru Wang, +4 authors, Xiaoxiang Guan.
Cancer Biother Radiopharm, 2014 Jun 03; 29(5). PMID: 24885919    Free PMC article.
Tumour volume doubling time of molecular breast cancer subtypes assessed by serial breast ultrasound.
Eun Bi Ryu, Jung Min Chang, +3 authors, Woo Kyung Moon.
Eur Radiol, 2014 Jun 05; 24(9). PMID: 24895040
Prognostic value of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in breast cancer.
Joohyun Woo, Heejung Park, +3 authors, Woosung Lim.
PLoS One, 2014 Jun 11; 9(6). PMID: 24914806    Free PMC article.
Luminal breast cancer classification according to proliferative indices: clinicopathological characteristics and short-term survival analysis.
Yan Sun, Gang Nie, +3 authors, Haibo Wang.
Med Oncol, 2014 Jun 18; 31(7). PMID: 24935624
Proposed new clinicopathological surrogate definitions of luminal A and luminal B (HER2-negative) intrinsic breast cancer subtypes.
Patrick Maisonneuve, Davide Disalvatore, +10 authors, Aron Goldhirsch.
Breast Cancer Res, 2014 Jun 22; 16(3). PMID: 24951027    Free PMC article.
Breast Cancer Survival Defined by the ER/PR/HER2 Subtypes and a Surrogate Classification according to Tumor Grade and Immunohistochemical Biomarkers.
Carol A Parise, Vincent Caggiano.
J Cancer Epidemiol, 2014 Jun 24; 2014. PMID: 24955090    Free PMC article.
Highly Cited.
Histopathological characterization of ductal carcinoma in situ (DCIS) of the breast according to HER2 amplification status and molecular subtype.
Mieke Van Bockstal, Kathleen Lambein, +6 authors, Louis Libbrecht.
Virchows Arch, 2014 Jun 30; 465(3). PMID: 24973889
Therapeutic targeting of integrin αvβ6 in breast cancer.
Kate M Moore, Gareth J Thomas, +25 authors, John F Marshall.
J Natl Cancer Inst, 2014 Jun 30; 106(8). PMID: 24974129    Free PMC article.
Evaluating the response of neoadjuvant chemotherapy for treatment of breast cancer: are tumor biomarkers and dynamic contrast enhanced MR images useful predictive tools?
Zijing Zhang, Wei Zhang, +10 authors, Qiang Zou.
J Thorac Dis, 2014 Jul 01; 6(6). PMID: 24977004    Free PMC article.
alphaB-crystallin is a marker of aggressive breast cancer behavior but does not independently predict for patient outcome: a combined analysis of two randomized studies.
Triantafyllia Koletsa, Flora Stavridi, +13 authors, George Fountzilas.
BMC Clin Pathol, 2014 Jul 06; 14. PMID: 24987308    Free PMC article.
Pathway-centric integrative analysis identifies RRM2 as a prognostic marker in breast cancer associated with poor survival and tamoxifen resistance.
Nagireddy Putluri, Suman Maity, +19 authors, Arun Sreekumar.
Neoplasia, 2014 Jul 14; 16(5). PMID: 25016594    Free PMC article.
The three receptor tyrosine kinases c-KIT, VEGFR2 and PDGFRα, closely spaced at 4q12, show increased protein expression in triple-negative breast cancer.
Sara Jansson, Pär-Ola Bendahl, +4 authors, Lisa Rydén.
PLoS One, 2014 Jul 16; 9(7). PMID: 25025175    Free PMC article.
Predictors of recurrence in breast cancer subtypes with negative lymph node in a Chinese population.
Xia Liu, Yong Guan, +4 authors, Yun Niu.
Int J Clin Exp Pathol, 2014 Jul 18; 7(6). PMID: 25031741    Free PMC article.
Identification of collaborative driver pathways in breast cancer.
Yang Liu, Zhenjun Hu.
BMC Genomics, 2014 Jul 19; 15. PMID: 25034939    Free PMC article.
Whole-body total lesion glycolysis measured on fluorodeoxyglucose positron emission tomography/computed tomography as a prognostic variable in metastatic breast cancer.
Yoko Satoh, Atsushi Nambu, Tomoaki Ichikawa, Hiroshi Onishi.
BMC Cancer, 2014 Jul 23; 14. PMID: 25048880    Free PMC article.
Ki67 expression and the effect of neo-adjuvant chemotherapy on luminal HER2-negative breast cancer.
Yoshiya Horimoto, Atsushi Arakawa, +7 authors, Mitsue Saito.
BMC Cancer, 2014 Jul 31; 14. PMID: 25073969    Free PMC article.
The mammary cellular hierarchy and breast cancer.
Samantha R Oakes, David Gallego-Ortega, Christopher J Ormandy.
Cell Mol Life Sci, 2014 Aug 01; 71(22). PMID: 25080108    Free PMC article.
Review.
How transferable are recommendations of the era of treating conventionally defined breast cancer for the era of molecularly characterised breast cancer?
Robert Königsberg, Christian Dittrich.
Gland Surg, 2012 Nov 01; 1(3). PMID: 25083440    Free PMC article.
Prognostic value of ki-67 in breast carcinoma: tissue microarray method versus whole section analysis- potentials and pitfalls.
Natalija Dedić Plavetić, Jasminka Jakić-Razumović, +3 authors, Damir Vrbanec.
Pathol Oncol Res, 2014 Aug 07; 21(2). PMID: 25096394
p85 protein expression is associated with poor survival in HER2-positive patients with advanced breast cancer treated with trastuzumab.
Kitty Pavlakis, Mattheos Bobos, +13 authors, George Fountzilas.
Pathol Oncol Res, 2014 Aug 08; 21(2). PMID: 25098276
Adjusting breast cancer patient prognosis with non-HER2-gene patterns on chromosome 17.
Vassiliki Kotoula, Mattheos Bobos, +12 authors, George Fountzilas.
PLoS One, 2014 Aug 08; 9(8). PMID: 25098819    Free PMC article.
Recurrent ESR1-CCDC170 rearrangements in an aggressive subset of oestrogen receptor-positive breast cancers.
Jamunarani Veeraraghavan, Ying Tan, +11 authors, Xiao-Song Wang.
Nat Commun, 2014 Aug 08; 5. PMID: 25099679    Free PMC article.
Predicting response and survival in chemotherapy-treated triple-negative breast cancer.
A Prat, A Lluch, +35 authors, E Alba.
Br J Cancer, 2014 Aug 08; 111(8). PMID: 25101563    Free PMC article.
Pathogenesis, prevention, diagnosis and treatment of breast cancer.
Rupen Shah, Kelly Rosso, S David Nathanson.
World J Clin Oncol, 2014 Aug 13; 5(3). PMID: 25114845    Free PMC article.
Review.
Biological subtypes of breast cancer: Prognostic and therapeutic implications.
Ozlem Yersal, Sabri Barutca.
World J Clin Oncol, 2014 Aug 13; 5(3). PMID: 25114856    Free PMC article.
Highly Cited. Review.
Presence of CHD1L over-expression is associated with aggressive tumor biology and is a novel prognostic biomarker for patient survival in human breast cancer.
Jiayi Wu, Yu Zong, +7 authors, Li Zhu.
PLoS One, 2014 Aug 26; 9(8). PMID: 25153161    Free PMC article.
Gene Expression Analysis Reveals Distinct Pathways of Resistance to Bevacizumab in Xenograft Models of Human ER-Positive Breast Cancer.
Yesim Gökmen-Polar, Chirayu P Goswami, +9 authors, George W Sledge.
J Cancer, 2014 Aug 27; 5(8). PMID: 25157274    Free PMC article.
[18F]-fluorodeoxyglucose positron emission tomography can contribute to discriminate patients with poor prognosis in hormone receptor-positive breast cancer.
Sung Gwe Ahn, Minkyung Lee, +6 authors, Joon Jeong.
PLoS One, 2014 Aug 29; 9(8). PMID: 25167062    Free PMC article.
Progesterone receptor status and Ki-67 index may predict early relapse in luminal B/HER2 negative breast cancer patients: a retrospective study.
Yu Zong, Li Zhu, +7 authors, Kunwei Shen.
PLoS One, 2014 Aug 30; 9(8). PMID: 25170613    Free PMC article.
Geographic differences in the distribution of molecular subtypes of breast cancer in Brazil.
Filomena M Carvalho, Lívia M Bacchi, +2 authors, Carlos E Bacchi.
BMC Womens Health, 2014 Sep 02; 14. PMID: 25174527    Free PMC article.
Membranous Nectin-4 expression is a risk factor for distant relapse of T1-T2, N0 luminal-A early breast cancer.
R Lattanzio, R Ghasemi, +7 authors, M Piantelli.
Oncogenesis, 2014 Sep 02; 3. PMID: 25178039    Free PMC article.
Immunohistochemical study of nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 in invasive breast carcinoma of no special type.
Krzysztof Symonowicz, Kamila Duś-Szachniewicz, +5 authors, Piotr Ziółkowski.
Exp Ther Med, 2014 Sep 05; 8(4). PMID: 25187794    Free PMC article.
Prognostic significance of FOXP3+ tumor-infiltrating lymphocytes in breast cancer depends on estrogen receptor and human epidermal growth factor receptor-2 expression status and concurrent cytotoxic T-cell infiltration.
Shuzhen Liu, William D Foulkes, +4 authors, Torsten O Nielsen.
Breast Cancer Res, 2014 Sep 07; 16(5). PMID: 25193543    Free PMC article.
HER2-positive endometrial cancer subtype carries poor prognosis.
Sylwia Lapińska-Szumczyk, Anna Supernat, +5 authors, Anna J Zaczek.
Clin Transl Sci, 2014 Sep 10; 7(6). PMID: 25201050    Free PMC article.
Impact of intrinsic subtype on predicting axillary lymph node metastasis in breast cancer.
Masataka Sawaki, Ai Idota, +7 authors, Hiroji Iwata.
Oncol Lett, 2014 Sep 10; 8(4). PMID: 25202396    Free PMC article.
Molecular breast cancer subtypes and therapies in a public hospital of northeastern Brazil.
Ana Cláudia de Macêdo Andrade, Carlos Alberis Ferreira Júnior, +3 authors, Mathias Weller.
BMC Womens Health, 2014 Sep 14; 14. PMID: 25216732    Free PMC article.
Contrast enhanced computed tomography is indicative for angiogenesis pattern and display prognostic significance in breast cancer.
Jianyi Li, Yang Zhang, +3 authors, Jiao Guo.
BMC Cancer, 2014 Sep 17; 14. PMID: 25224155    Free PMC article.
HER-2 positive breast cancer is associated with an increased risk of positive cavity margins after initial lumpectomy.
Haixia Jia, Weijuan Jia, +14 authors, Fengxi Su.
World J Surg Oncol, 2014 Sep 23; 12. PMID: 25241216    Free PMC article.
Triple-negative vimentin-positive heterogeneous feline mammary carcinomas as a potential comparative model for breast cancer.
Diego Caliari, Valentina Zappulli, +4 authors, Massimo Castagnaro.
BMC Vet Res, 2014 Sep 25; 10. PMID: 25249140    Free PMC article.
Difference between Luminal A and Luminal B Subtypes According to Ki-67, Tumor Size, and Progesterone Receptor Negativity Providing Prognostic Information.
Zorka Inic, Milan Zegarac, +6 authors, Snezana Jancic.
Clin Med Insights Oncol, 2014 Sep 25; 8. PMID: 25249766    Free PMC article.
MicroRNA expression as risk biomarker of breast cancer metastasis: a pilot retrospective case-cohort study.
Augusto L F Marino, Adriane F Evangelista, +6 authors, Marcia M C Marques.
BMC Cancer, 2014 Oct 04; 14. PMID: 25277099    Free PMC article.
Metabolic syndrome-breast cancer link varies by intrinsic molecular subtype.
Immacolata Capasso, Emanuela Esposito, +13 authors, Giuseppe D'Aiuto.
Diabetol Metab Syndr, 2014 Oct 07; 6(1). PMID: 25285159    Free PMC article.
Tumour 18 F-FDG Uptake on preoperative PET/CT may predict axillary lymph node metastasis in ER-positive/HER2-negative and HER2-positive breast cancer subtypes.
Jin You Kim, Suck Hong Lee, +2 authors, Young Tae Bae.
Eur Radiol, 2014 Oct 10; 25(4). PMID: 25298170
Combination of the mTOR inhibitor ridaforolimus and the anti-IGF1R monoclonal antibody dalotuzumab: preclinical characterization and phase I clinical trial.
Serena Di Cosimo, Sriram Sathyanarayanan, +15 authors, José Baselga.
Clin Cancer Res, 2014 Oct 17; 21(1). PMID: 25320355    Free PMC article.
Absence of gamma-interferon-inducible lysosomal thiol reductase (GILT) is associated with poor disease-free survival in breast cancer patients.
Yu-Juan Xiang, Ming-Ming Guo, +14 authors, Zhi-Gang Yu.
PLoS One, 2014 Oct 22; 9(10). PMID: 25333930    Free PMC article.
Integrative investigation on breast cancer in ER, PR and HER2-defined subgroups using mRNA and miRNA expression profiling.
Xiaofeng Dai, Ana Chen, Zhonghu Bai.
Sci Rep, 2014 Oct 24; 4. PMID: 25338681    Free PMC article.
Molecular subtype and tumor characteristics of breast cancer metastases as assessed by gene expression significantly influence patient post-relapse survival.
N P Tobin, J C Harrell, +14 authors, TEX Trialists Group.
Ann Oncol, 2014 Nov 02; 26(1). PMID: 25361981    Free PMC article.
Evaluation of Ki67 expression across distinct categories of breast cancer specimens: a population-based study of matched surgical specimens, core needle biopsies and tissue microarrays.
Gøril Knutsvik, Ingunn M Stefansson, +4 authors, Lars A Akslen.
PLoS One, 2014 Nov 07; 9(11). PMID: 25375149    Free PMC article.
Development of circulating tumor cell-endocrine therapy index in patients with hormone receptor-positive breast cancer.
Costanza Paoletti, Maria C Muñiz, +13 authors, Daniel F Hayes.
Clin Cancer Res, 2014 Nov 09; 21(11). PMID: 25381338    Free PMC article.
Lobular breast cancers lack the inverse relationship between ER/PR status and cell growth rate characteristic of ductal cancers in two independent patient cohorts: implications for tumor biology and adjuvant therapy.
Hilda Wong, Silvia Lau, +4 authors, Richard J Epstein.
BMC Cancer, 2014 Nov 12; 14. PMID: 25385074    Free PMC article.
Pathological non-response to chemotherapy in a neoadjuvant setting of breast cancer: an inter-institutional study.
D Balmativola, C Marchiò, +26 authors, A Sapino.
Breast Cancer Res Treat, 2014 Nov 15; 148(3). PMID: 25395316    Free PMC article.
Male breast carcinoma: a clinicopathological and immunohistochemical characterization study.
Ruoji Zhou, Lin Yu, +6 authors, Wentao Yang.
Int J Clin Exp Pathol, 2014 Nov 18; 7(10). PMID: 25400768    Free PMC article.
Single-nucleotide polymorphisms in DNA bypass polymerase genes and association with breast cancer and breast cancer subtypes among African Americans and Whites.
Leila Family, Jeannette T Bensen, +3 authors, Andrew F Olshan.
Breast Cancer Res Treat, 2014 Nov 25; 149(1). PMID: 25417172    Free PMC article.
Mining cancer gene expression databases for latent information on intronic microRNAs.
Simona Monterisi, Giovanni D'Ario, +11 authors, Fabrizio Bianchi.
Mol Oncol, 2014 Dec 03; 9(2). PMID: 25459350    Free PMC article.
Pregnancy-associated plasma protein-A expression in human breast cancer.
Aaron S Mansfield, Daniel W Visscher, +4 authors, Cheryl A Conover.
Growth Horm IGF Res, 2014 Dec 04; 24(6). PMID: 25468445    Free PMC article.
Inclusion of KI67 significantly improves performance of the PREDICT prognostication and prediction model for early breast cancer.
Gordon C Wishart, Emad Rakha, +6 authors, Paul D P Pharoah.
BMC Cancer, 2014 Dec 05; 14. PMID: 25472026    Free PMC article.
The histone chaperone HJURP is a new independent prognostic marker for luminal A breast carcinoma.
Rocío Montes de Oca, Zachary A Gurard-Levin, +12 authors, Geneviève Almouzni.
Mol Oncol, 2014 Dec 17; 9(3). PMID: 25497280    Free PMC article.
Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature.
Josie Hayes, Helene Thygesen, +8 authors, Sean E Lawler.
Mol Oncol, 2014 Dec 17; 9(3). PMID: 25499534    Free PMC article.
Expression of Histone Deacetylases HDAC1, HDAC2, HDAC3, and HDAC6 in Invasive Ductal Carcinomas of the Breast.
Jinwon Seo, Soo Kee Min, +4 authors, Young-Su Ju.
J Breast Cancer, 2014 Dec 31; 17(4). PMID: 25548579    Free PMC article.
Subtype is a predictive factor of nonsentinel lymph node involvement in sentinel node-positive breast cancer patients.
Kaptan Gülben, Uğur Berberoğlu, Ogün Aydoğan, Volkan Kınaş.
J Breast Cancer, 2014 Dec 31; 17(4). PMID: 25548586    Free PMC article.
Kallikrein-related peptidase 5 induces miRNA-mediated anti-oncogenic pathways in breast cancer.
Konstantinos G Sidiropoulos, Nicole M A White, +7 authors, George M Yousef.
Oncoscience, 2015 Jan 17; 1(11). PMID: 25593998    Free PMC article.
Gene expression profiling of lobular carcinoma in situ reveals candidate precursor genes for invasion.
Victor P Andrade, Mary Morrogh, +12 authors, Tari A King.
Mol Oncol, 2015 Jan 21; 9(4). PMID: 25601220    Free PMC article.
Methylation of tumor suppressor genes is related with copy number aberrations in breast cancer.
Rosa Murria, Sarai Palanca, +12 authors, Pascual Bolufer.
Am J Cancer Res, 2015 Jan 30; 5(1). PMID: 25628946    Free PMC article.
Clinical and histopathological factors associated with Ki-67 expression in breast cancer patients.
Gul Alco, Atilla Bozdogan, +8 authors, Vahit Ozmen.
Oncol Lett, 2015 Feb 11; 9(3). PMID: 25663855    Free PMC article.
Biomarkers in Patients with Metastatic Breast Cancer and the PRAEGNANT Study Network.
P A Fasching, S Y Brucker, +14 authors, A Schneeweiss.
Geburtshilfe Frauenheilkd, 2015 Feb 17; 75(1). PMID: 25684786    Free PMC article.
Utility of (18)F FDG-PET/CT for predicting prognosis of luminal-type breast cancer.
Kenjiro Aogi, Takayuki Kadoya, +4 authors, Morihito Okada.
Breast Cancer Res Treat, 2015 Feb 24; 150(1). PMID: 25697596    Free PMC article.
An international study to increase concordance in Ki67 scoring.
Mei-Yin C Polley, Samuel C Y Leung, +28 authors, Torsten O Nielsen.
Mod Pathol, 2015 Feb 24; 28(6). PMID: 25698062
Highly Cited.
The origin of breast tumor heterogeneity.
A Skibinski, C Kuperwasser.
Oncogene, 2015 Feb 24; 34(42). PMID: 25703331    Free PMC article.
Highly Cited. Review.
The predictive accuracy of PREDICT: a personalized decision-making tool for Southeast Asian women with breast cancer.
Hoong-Seam Wong, Shridevi Subramaniam, +7 authors, Nirmala Bhoo-Pathy.
Medicine (Baltimore), 2015 Feb 26; 94(8). PMID: 25715267    Free PMC article.
In stage II/III lymph node-positive breast cancer patients less than 55 years of age, keratin 8 expression in lymph node metastases but not in the primary tumour is an indicator of better survival.
Serena Bonin, Danae Pracella, +2 authors, Giorgio Stanta.
Virchows Arch, 2015 Mar 01; 466(5). PMID: 25724181
Tubal Ligation Induces Quiescence in the Epithelia of the Fallopian Tube Fimbria.
Ekaterina Tiourin, Victor S Velasco, +3 authors, Sanaz Memarzadeh.
Reprod Sci, 2015 Mar 05; 22(10). PMID: 25736327    Free PMC article.
The CCL2 chemokine is a negative regulator of autophagy and necrosis in luminal B breast cancer cells.
Wei Bin Fang, Min Yao, +5 authors, Nikki Cheng.
Breast Cancer Res Treat, 2015 Mar 07; 150(2). PMID: 25744294    Free PMC article.
Can molecular subtyping replace axillary nodal status as prognostic marker in breast cancer?
Debarshi Jana, Diptendra Kumar Sarkar, +3 authors, Syamsundar Mandal.
Indian J Surg Oncol, 2015 Mar 15; 5(4). PMID: 25767340    Free PMC article.
Ki67--no evidence for its use in node-positive breast cancer.
Fabrice Andre, Monica Arnedos, +2 authors, Suzette Delaloge.
Nat Rev Clin Oncol, 2015 Mar 18; 12(5). PMID: 25781576
Review.
Abnormal expression of the Notch and Wnt/β-catenin signaling pathways in stem-like ALDHhiCD44+ cells correlates highly with Ki-67 expression in breast cancer.
Junwei Cui, Peng Li, +2 authors, Wei Wei.
Oncol Lett, 2015 Mar 20; 9(4). PMID: 25789008    Free PMC article.
Retrospective analysis of metastatic behaviour of breast cancer subtypes.
C Dilara Savci-Heijink, Hans Halfwerk, +3 authors, Marc J van de Vijver.
Breast Cancer Res Treat, 2015 Mar 31; 150(3). PMID: 25820592    Free PMC article.
Expression of ribosome-binding protein 1 correlates with shorter survival in Her-2 positive breast cancer.
Xiaoshuan Liang, Shanshan Sun, +6 authors, Da Pang.
Cancer Sci, 2015 Apr 08; 106(6). PMID: 25845758    Free PMC article.
Clinical significance of topoisomerase 2A expression and gene change in operable invasive breast cancer.
Jiang-Hua Qiao, De-Chuang Jiao, +2 authors, Zhen-Zhen Liu.
Tumour Biol, 2015 Apr 08; 36(9). PMID: 25846735
Patient-derived xenograft models of breast cancer and their predictive power.
James R Whittle, Michael T Lewis, Geoffrey J Lindeman, Jane E Visvader.
Breast Cancer Res, 2015 Apr 08; 17. PMID: 25849559    Free PMC article.
Highly Cited. Review.
Phosphoglycerate kinase-1 is a predictor of poor survival and a novel prognostic biomarker of chemoresistance to paclitaxel treatment in breast cancer.
S Sun, X Liang, +8 authors, D Pang.
Br J Cancer, 2015 Apr 14; 112(8). PMID: 25867275    Free PMC article.
Altered PPP2R2A and Cyclin D1 expression defines a subgroup of aggressive luminal-like breast cancer.
Francisco Beca, Miguel Pereira, +2 authors, Fernando Schmitt.
BMC Cancer, 2015 Apr 17; 15. PMID: 25879784    Free PMC article.
Prognostic Relevance of Circulating Tumor Cells in Molecular Subtypes of Breast Cancer.
M Banys-Paluchowski, H Schneck, +7 authors, H Neubauer.
Geburtshilfe Frauenheilkd, 2015 Apr 29; 75(3). PMID: 25914415    Free PMC article.
An interobserver reproducibility analysis of Ki67 visual assessment in breast cancer.
Ruohong Shui, Baohua Yu, +2 authors, Wentao Yang.
PLoS One, 2015 May 02; 10(5). PMID: 25932921    Free PMC article.
Association between ¹⁸F-FDG uptake and molecular subtype of breast cancer.
Kazuhiro Kitajima, Kazuhito Fukushima, +6 authors, Shozo Hirota.
Eur J Nucl Med Mol Imaging, 2015 May 08; 42(9). PMID: 25947575
Pilot study investigating the prognostic significance of thymidine phosphorylase expression in patients with metastatic breast cancer: a single institution retrospective analysis.
Anna Lisa Tedeschi, Zohreh Eslami, +6 authors, Catalin Mihalcioiu.
Onco Targets Ther, 2015 May 12; 8. PMID: 25960662    Free PMC article.
Chemopreventive Activity of Ferulago angulate against Breast Tumor in Rats and the Apoptotic Effect of Polycerasoidin in MCF7 Cells: A Bioassay-Guided Approach.
Hamed Karimian, Mehran Fadaeinasab, +6 authors, Mohamad Ibrahim Noordin.
PLoS One, 2015 May 23; 10(5). PMID: 25996383    Free PMC article.
From bench to bedside: What do we know about hormone receptor-positive and human epidermal growth factor receptor 2-positive breast cancer?
Victoria Shang Wu, Noriko Kanaya, +2 authors, Shiuan Chen.
J Steroid Biochem Mol Biol, 2015 May 23; 153. PMID: 25998416    Free PMC article.
Review.
Evaluation of the prognostic significance of HER family mRNA expression in high-risk early breast cancer: a Hellenic Cooperative Oncology Group (HeCOG) validation study.
Angelos Koutras, Konstantine T Kalogeras, +16 authors, George Fountzilas.
J Transl Med, 2015 May 30; 13. PMID: 26021752    Free PMC article.
Molecular Phenotype of Breast Cancer According to Time Since Last Pregnancy in a Large Cohort of Young Women.
Laura C Collins, Shari Gelber, +12 authors, Ann H Partridge.
Oncologist, 2015 May 31; 20(7). PMID: 26025931    Free PMC article.
Identifying ultrasound and clinical features of breast cancer molecular subtypes by ensemble decision.
Lei Zhang, Jing Li, +7 authors, Jiawei Tian.
Sci Rep, 2015 Jun 06; 5. PMID: 26046791    Free PMC article.
Appraisal of the technologies and review of the genomic landscape of ductal carcinoma in situ of the breast.
Jia-Min B Pang, Kylie L Gorringe, +3 authors, Stephen B Fox.
Breast Cancer Res, 2015 Jun 17; 17. PMID: 26078038    Free PMC article.
Review.
Using proliferative markers and Oncotype DX in therapeutic decision-making for breast cancer: the B.C. experience.
E Baxter, L Gondara, +5 authors, S Tyldesley.
Curr Oncol, 2015 Jun 20; 22(3). PMID: 26089718    Free PMC article.
Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer.
Grace O Silva, Xiaping He, +8 authors, Charles M Perou.
Breast Cancer Res Treat, 2015 Jun 26; 152(2). PMID: 26109346    Free PMC article.
Clinicopathological Features and Prognosis of Metaplastic Breast Carcinoma: Experience of a Major Chinese Cancer Center.
Yiqian Zhang, Feng Lv, +11 authors, Xiaojing Guo.
PLoS One, 2015 Jun 27; 10(6). PMID: 26115045    Free PMC article.
Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance.
Loredana Vesci, Valeria Carollo, +4 authors, Rita De Santis.
Oncol Rep, 2015 Jul 03; 34(3). PMID: 26133490    Free PMC article.
Evaluation of the pathological response and prognosis following neoadjuvant chemotherapy in molecular subtypes of breast cancer.
Yue Zhao, Xiaoqiu Dong, +4 authors, Dongwei Zhang.
Onco Targets Ther, 2015 Jul 08; 8. PMID: 26150728    Free PMC article.
Differences in Clinical Outcomes between Luminal A and B Type Breast Cancers according to the St. Gallen Consensus 2013.
Hyo Jung Ahn, Soo Jin Jung, +2 authors, Hye-Kyoung Yoon.
J Breast Cancer, 2015 Jul 15; 18(2). PMID: 26155291    Free PMC article.
The impact of preoperative axillary ultrasonography in T1 breast tumours.
Javier del Riego, María Jesús Diaz-Ruiz, +5 authors, Grup de Mama Vallès-Osona-Bages (GMVOB; Cooperative Breast Workgroup Vallés-Osona-Bagés).
Eur Radiol, 2015 Jul 15; 26(4). PMID: 26162580
High expression of valosin-containing protein predicts poor prognosis in patients with breast carcinoma.
Yan Cui, Ming Niu, +3 authors, Da Pang.
Tumour Biol, 2015 Jul 15; 36(12). PMID: 26168958
Evaluation of an Optimal Cut-Off Point for the Ki-67 Index as a Prognostic Factor in Primary Breast Cancer: A Retrospective Study.
Rumiko Tashima, Reiki Nishimura, +6 authors, Nobuyuki Arima.
PLoS One, 2015 Jul 16; 10(7). PMID: 26177501    Free PMC article.
Targeting Mdmx to treat breast cancers with wild-type p53.
S Haupt, D Buckley, +13 authors, Y Haupt.
Cell Death Dis, 2015 Jul 17; 6. PMID: 26181202    Free PMC article.
miR-205-5p-mediated downregulation of ErbB/HER receptors in breast cancer stem cells results in targeted therapy resistance.
A De Cola, S Volpe, +13 authors, V De Laurenzi.
Cell Death Dis, 2015 Jul 17; 6. PMID: 26181203    Free PMC article.
Response: Expression of Glucagon-Like Peptide-1 Receptor in Papillary Thyroid Carcinoma and Its Clinicopathologic Significance (Endocrinol Metab 2014;29:536-44, Min Jung Jung et al.).
Min Jung Jung, Su Kyoung Kwon.
Endocrinol Metab (Seoul), 2015 Jul 22; 30(2). PMID: 26194083    Free PMC article.
Monitoring therapeutic efficacy of sunitinib using [(18)F]FDG and [(18)F]FMISO PET in an immunocompetent model of luminal B (HER2-positive)-type mammary carcinoma.
Benoît Thézé, Nicholas Bernards, +5 authors, Raphaël Boisgard.
BMC Cancer, 2015 Jul 23; 15. PMID: 26198000    Free PMC article.
Digital imaging in the immunohistochemical evaluation of the proliferation markers Ki67, MCM2 and Geminin, in early breast cancer, and their putative prognostic value.
Shalaka Joshi, Johnathan Watkins, +4 authors, Sarah E Pinder.
BMC Cancer, 2015 Jul 25; 15. PMID: 26205655    Free PMC article.
Relative Effectiveness of Letrozole Compared With Tamoxifen for Patients With Lobular Carcinoma in the BIG 1-98 Trial.
Otto Metzger Filho, Anita Giobbie-Hurder, +12 authors, Aron Goldhirsch.
J Clin Oncol, 2015 Jul 29; 33(25). PMID: 26215945    Free PMC article.
Electrochemotherapy in the Treatment of Cutaneous Metastases from Breast Cancer: A Multicenter Cohort Analysis.
C Cabula, L G Campana, +14 authors, R Agresti.
Ann Surg Oncol, 2015 Aug 06; 22 Suppl 3. PMID: 26242370    Free PMC article.
p27(Kip1) and Ser10-phosphorylated p27(Kip1) in breast cancer: clinical significance and expression.
Wei Song, Ruilian Xie, +6 authors, Xiaoxiang Guan.
Onco Targets Ther, 2015 Aug 06; 8. PMID: 26244023    Free PMC article.
Polymorphisms in poly (ADP-ribose) polymerase-1 (PARP1) promoter and 3' untranslated region and their association with PARP1 expression in breast cancer patients.
Lili Zhai, Shuai Li, +7 authors, Li Fu.
Int J Clin Exp Pathol, 2015 Aug 12; 8(6). PMID: 26261599    Free PMC article.
Differential involvement of RASSF2 hypermethylation in breast cancer subtypes and their prognosis.
Noemi Perez-Janices, Idoia Blanco-Luquin, +13 authors, David Guerrero-Setas.
Oncotarget, 2015 Aug 19; 6(27). PMID: 26284587    Free PMC article.
Development and verification of the PAM50-based Prosigna breast cancer gene signature assay.
Brett Wallden, James Storhoff, +16 authors, Joel S Parker.
BMC Med Genomics, 2015 Aug 25; 8. PMID: 26297356    Free PMC article.
Highly Cited.
Insights into Orphan Nuclear Receptors as Prognostic Markers and Novel Therapeutic Targets for Breast Cancer.
Reidun Aesoy, Colin D Clyne, Ashwini L Chand.
Front Endocrinol (Lausanne), 2015 Aug 25; 6. PMID: 26300846    Free PMC article.
Review.
Correlation Between Clinical-Pathologic Factors and Long-Term Follow-Up in Young Breast Cancer Patients.
Yue Zhao, Xiaoqiu Dong, +2 authors, Dongwei Zhang.
Transl Oncol, 2015 Aug 28; 8(4). PMID: 26310372    Free PMC article.
Breast Cancer Anti-Estrogen Resistance 4 (BCAR4) Drives Proliferation of IPH-926 lobular Carcinoma Cells.
Ton van Agthoven, Lambert C J Dorssers, +3 authors, Matthias Christgen.
PLoS One, 2015 Sep 01; 10(8). PMID: 26317614    Free PMC article.
Retinoic acid-related orphan receptor C isoform 2 expression and its prognostic significance for non-small cell lung cancer.
Qi Huang, Jinshuo Fan, +9 authors, Yang Jin.
J Cancer Res Clin Oncol, 2015 Sep 01; 142(1). PMID: 26319393
Immunohistochemical, genetic and epigenetic profiles of hereditary and triple negative breast cancers. Relevance in personalized medicine.
Rosa Murria, Sarai Palanca, +14 authors, Pascual Bolufer.
Am J Cancer Res, 2015 Sep 04; 5(7). PMID: 26328265    Free PMC article.
Postmenopausal mammographic breast density and subsequent breast cancer risk according to selected tissue markers.
Lusine Yaghjyan, Andreas Pettersson, +6 authors, Rulla M Tamimi.
Br J Cancer, 2015 Sep 04; 113(7). PMID: 26335607    Free PMC article.
Inhibitory effects of O-methylated isoflavone glycitein on human breast cancer SKBR-3 cells.
Bo Zhang, Jun-Ping Su, +2 authors, Yong-Hong Liu.
Int J Clin Exp Pathol, 2015 Sep 05; 8(7). PMID: 26339345    Free PMC article.
Associations between sociodemographic and clinicopathological factors and breast cancer subtypes in a population-based study.
Adana A M Llanos, Sheenu Chandwani, +4 authors, Kitaw Demissie.
Cancer Causes Control, 2015 Sep 18; 26(12). PMID: 26376894    Free PMC article.
Prognostic impact of discrepant Ki67 and mitotic index on hormone receptor-positive, HER2-negative breast carcinoma.
L Rossi, E Laas, +6 authors, F Reyal.
Br J Cancer, 2015 Sep 18; 113(7). PMID: 26379080    Free PMC article.
Outcomes of special histotypes of breast cancer after adjuvant endocrine therapy with letrozole or tamoxifen in the monotherapy cohort of the BIG 1-98 trial.
E Munzone, A Giobbie-Hurder, +13 authors, International Breast Cancer Study Group and the BIG 1-98 Collaborative Group.
Ann Oncol, 2015 Sep 21; 26(12). PMID: 26387144    Free PMC article.
Molecular portraits revealing the heterogeneity of breast tumor subtypes defined using immunohistochemistry markers.
Xiaofeng Dai, Yang Li, Zhonghu Bai, Xu-Qing Tang.
Sci Rep, 2015 Sep 26; 5. PMID: 26404658    Free PMC article.
Comprehensive prognostic analysis in breast cancer integrating clinical, tumoral, micro-environmental and immunohistochemical criteria.
Isabelle de Mascarel, Marc Debled, +8 authors, Gaëtan MacGrogan.
Springerplus, 2015 Sep 26; 4. PMID: 26405647    Free PMC article.
The importance of tissue handling of surgically removed breast cancer for an accurate assessment of the Ki-67 index.
Nobuyuki Arima, Reiki Nishimura, +6 authors, Yasuo Toyozumi.
J Clin Pathol, 2015 Oct 01; 69(3). PMID: 26420767    Free PMC article.
Expression and Significance of COX-2 and Ki-67 in Hepatolithiasis with Bile Duct Carcinoma.
Ping Wang, Yu He, +4 authors, Yanmin Liu.
Med Sci Monit, 2015 Oct 02; 21. PMID: 26423666    Free PMC article.
Targeting MCM2 function as a novel strategy for the treatment of highly malignant breast tumors.
Shinya Abe, Kouhei Yamamoto, +4 authors, Masanobu Kitagawa.
Oncotarget, 2015 Oct 03; 6(33). PMID: 26430873    Free PMC article.
Expression of alpha B crystallin and BCL2 in patients with infiltrating ductal carcinoma.
Mee-Seon Kim, Hyoun Wook Lee, Si-Youl Jun, Eun Hee Lee.
Int J Clin Exp Pathol, 2015 Oct 16; 8(8). PMID: 26464626    Free PMC article.
Prognostic Nomogram for Prediction of Axillary Pathologic Complete Response After Neoadjuvant Chemotherapy in Cytologically Proven Node-Positive Breast Cancer.
Jee Ye Kim, Hyung Seok Park, +3 authors, Seung Il Kim.
Medicine (Baltimore), 2015 Oct 30; 94(43). PMID: 26512562    Free PMC article.
Surgery time interval and molecular subtype may influence Ki67 change after core needle biopsy in breast cancer patients.
Xiaosong Chen, Siji Zhu, +9 authors, Kunwei Shen.
BMC Cancer, 2015 Oct 31; 15. PMID: 26514283    Free PMC article.
High Expression of Pyruvate Kinase M2 is Associated with Chemosensitivity to Epirubicin and 5-Fluorouracil in Breast Cancer.
Yang Lin, Feng Lv, +5 authors, Li Fu.
J Cancer, 2015 Oct 31; 6(11). PMID: 26516361    Free PMC article.
Differentiation between genetic mutations of breast cancer by breath volatolomics.
Orna Barash, Wei Zhang, +7 authors, Hossam Haick.
Oncotarget, 2015 Nov 06; 6(42). PMID: 26540569    Free PMC article.
γKlotho is a novel marker and cell survival factor in a subset of triple negative breast cancers.
Nuša Trošt, Samuel Peña-Llopis, +4 authors, Elisabeth D Martinez.
Oncotarget, 2015 Nov 12; 7(3). PMID: 26556877    Free PMC article.
Loss of antigenicity with tissue age in breast cancer.
Susan E Combs, Gang Han, +3 authors, David L Rimm.
Lab Invest, 2015 Nov 17; 96(3). PMID: 26568292
High expression of FOXR2 in breast cancer correlates with poor prognosis.
Haiping Song, Wenshan He, +2 authors, Tao Huang.
Tumour Biol, 2015 Nov 26; 37(5). PMID: 26596836
HOXD13 methylation status is a prognostic indicator in breast cancer.
Zhenbin Zhong, Ming Shan, +5 authors, Da Pang.
Int J Clin Exp Pathol, 2015 Dec 01; 8(9). PMID: 26617782    Free PMC article.
Ki-67 and caspase expression in breast carcinoma: does variance in locational sampling exist?
Filinte Deniz, Kaymakci Dilek, +2 authors, Kaya Handan.
Int J Clin Exp Pathol, 2015 Dec 01; 8(9). PMID: 26617854    Free PMC article.
Prognostic significance of HOXD13 expression in human breast cancer.
Zhen-Bin Zhong, Ming Shan, +7 authors, Da Pang.
Int J Clin Exp Pathol, 2015 Dec 01; 8(9). PMID: 26617867    Free PMC article.
Associations and indications of Ki67 expression with clinicopathological parameters and molecular subtypes in invasive breast cancer: A population-based study.
Jinzhong Sun, Chuang Chen, +9 authors, Shengrong Sun.
Oncol Lett, 2015 Dec 02; 10(3). PMID: 26622743    Free PMC article.
Cell surface GRP78: A potential marker of good prognosis and response to chemotherapy in breast cancer.
Rinat Yerushalmi, Annat Raiter, Karen Nalbandyan, Britta Hardy.
Oncol Lett, 2015 Dec 02; 10(4). PMID: 26622810    Free PMC article.
Biomarkers in Breast Cancer - An Update.
M Schmidt, P A Fasching, M W Beckmann, H Kölbl.
Geburtshilfe Frauenheilkd, 2012 Sep 01; 72(9). PMID: 26640290    Free PMC article.
Intrinsic subtypes and genomic signatures of primary breast cancer and prognosis after systemic relapse.
Claudette Falato, Nicholas P Tobin, +3 authors, Theodoros Foukakis.
Mol Oncol, 2015 Dec 15; 10(4). PMID: 26651914    Free PMC article.
Neuroendocrine Carcinoma of the Breast: Current Evidence and Future Perspectives.
Alessandro Inno, Giuseppe Bogina, +8 authors, Stefania Gori.
Oncologist, 2015 Dec 15; 21(1). PMID: 26659223    Free PMC article.
Review.
TP53 Mutational Analysis Enhances the Prognostic Accuracy of IHC4 and PAM50 Assays.
Ching-Hung Lin, I-Chiun Chen, +11 authors, Ann-Lii Cheng.
Sci Rep, 2015 Dec 17; 5. PMID: 26671300    Free PMC article.
Reproductive risk factors in relation to molecular subtypes of breast cancer: Results from the nurses' health studies.
Julia S Sisti, Laura C Collins, +3 authors, A Heather Eliassen.
Int J Cancer, 2015 Dec 20; 138(10). PMID: 26684063    Free PMC article.
Breast cancer intrinsic subtype classification, clinical use and future trends.
Xiaofeng Dai, Ting Li, +4 authors, Bozhi Shi.
Am J Cancer Res, 2015 Dec 23; 5(10). PMID: 26693050    Free PMC article.
Highly Cited. Review.
Negative association between GATA3 and fascin could predict relapse-free and overall survival in patients with breast cancer.
Kyueng-Whan Min, Dong-Hoon Kim, +14 authors, Kyoung Min Moon.
Virchows Arch, 2016 Jan 01; 468(4). PMID: 26719157
Decreased Wnt5a Expression is a Poor Prognostic Factor in Triple-Negative Breast Cancer.
ZhenBin Zhong, Ming Shan, +3 authors, Da Pang.
Med Sci Monit, 2016 Jan 02; 22. PMID: 26721633    Free PMC article.
Ki-67 is a prognostic marker for hormone receptor positive tumors.
M E Pérez-López, J García-Gómez, +3 authors, T García-Caballero.
Clin Transl Oncol, 2016 Jan 09; 18(10). PMID: 26742937    Free PMC article.
Bimodality of intratumor Ki67 expression is an independent prognostic factor of overall survival in patients with invasive breast carcinoma.
Arvydas Laurinavicius, Benoit Plancoulaine, +11 authors, Ian O Ellis.
Virchows Arch, 2016 Jan 29; 468(4). PMID: 26818835
Expression of eag1 channel associated with the aggressive clinicopathological features and subtype of breast cancer.
Guang-Xu Liu, Yun-Cui Yu, +4 authors, Yan He.
Int J Clin Exp Pathol, 2016 Jan 30; 8(11). PMID: 26823849    Free PMC article.
Breast Cancer-Associated Fibroblasts: Where We Are and Where We Need to Go.
Rachel J Buchsbaum, Sun Young Oh.
Cancers (Basel), 2016 Feb 02; 8(2). PMID: 26828520    Free PMC article.
Highly Cited. Review.
The association of subtypes of breast cancer with tumour characteristics and reproductive factors in 1326 Mexican women.
Gabriel Pérez-Rodríguez, Catalina Aranda-Moreno, Ivonne M Olivares-Corichi, Jose R Garcia-Sanchez.
Contemp Oncol (Pozn), 2016 Feb 05; 19(6). PMID: 26843843    Free PMC article.
Targeted therapies with companion diagnostics in the management of breast cancer: current perspectives.
Meagan B Myers.
Pharmgenomics Pers Med, 2016 Feb 10; 9. PMID: 26858530    Free PMC article.
Review.
Interobserver Variability of Ki-67 Measurement in Breast Cancer.
Yul Ri Chung, Min Hye Jang, +3 authors, Korean Breast Pathology Ki-67 Study Group.
J Pathol Transl Med, 2016 Feb 16; 50(2). PMID: 26875758    Free PMC article.
Serum HER2 levels are increased in cats with mammary carcinomas and predict tissue HER2 status.
Maria Soares, Rita Ribeiro, +4 authors, Fernando Ferreira.
Oncotarget, 2016 Feb 26; 7(14). PMID: 26909614    Free PMC article.
A Comparison of Visual Assessment and Automated Digital Image Analysis of Ki67 Labeling Index in Breast Cancer.
Fangfang Zhong, Rui Bi, +3 authors, Ruohong Shui.
PLoS One, 2016 Mar 02; 11(2). PMID: 26928407    Free PMC article.
Long non-coding RNAs as prognostic markers in human breast cancer.
Hairong Liu, Juan Li, +7 authors, Yin-Yuan Mo.
Oncotarget, 2016 Mar 05; 7(15). PMID: 26942882    Free PMC article.
Highly Cited.
Association Between Insulin Resistance and Luminal B Subtype Breast Cancer in Postmenopausal Women.
Sanggeun Nam, Seho Park, +3 authors, Seung Il Kim.
Medicine (Baltimore), 2016 Mar 06; 95(9). PMID: 26945364    Free PMC article.
Risk Factors Associated with Discordant Ki-67 Levels between Preoperative Biopsy and Postoperative Surgical Specimens in Breast Cancers.
Hyung Sun Kim, Seho Park, +6 authors, Byeong-Woo Park.
PLoS One, 2016 Mar 10; 11(3). PMID: 26954364    Free PMC article.
Nomograms to estimate long-term overall survival and breast cancer-specific survival of patients with luminal breast cancer.
Wei Sun, Yi-Zhou Jiang, +2 authors, Zhi-Ming Shao.
Oncotarget, 2016 Mar 12; 7(15). PMID: 26967253    Free PMC article.
Triple-negative breast cancer exhibits a favorable response to neoadjuvant chemotherapy independent of the expression of topoisomerase IIα.
Hiroko Nogi, Ken Uchida, +7 authors, Hiroshi Takeyama.
Mol Clin Oncol, 2016 Mar 22; 4(3). PMID: 26998288    Free PMC article.
Subpopulation Treatment Effect Pattern Plot (STEPP) analysis of Ki67 assay according to histology: prognostic relevance for resected early stage 'pure' and 'mixed' lobular breast cancer.
Luisa Carbognin, Isabella Sperduti, +13 authors, Emilio Bria.
J Exp Clin Cancer Res, 2016 Mar 24; 35. PMID: 27000271    Free PMC article.
Role of dietary bioactive natural products in estrogen receptor-positive breast cancer.
Min Ji Bak, Soumyasri Das Gupta, Joseph Wahler, Nanjoo Suh.
Semin Cancer Biol, 2016 Mar 27; 40-41. PMID: 27016037    Free PMC article.
Review.
Analysis of TRRAP as a Potential Molecular Marker and Therapeutic Target for Breast Cancer.
Ji Wang, Ming Shan, +4 authors, Da Pang.
J Breast Cancer, 2016 Apr 12; 19(1). PMID: 27066097    Free PMC article.
Prognostic value of Ki67 and p53 in patients with estrogen receptor-positive and human epidermal growth factor receptor 2-negative breast cancer: Validation of the cut-off value of the Ki67 labeling index as a predictive factor.
Masahiro Ohara, Kazuo Matsuura, +5 authors, Toshiyuki Itamoto.
Mol Clin Oncol, 2016 Apr 14; 4(4). PMID: 27073684    Free PMC article.
Elevated expression of chemokine C-C ligand 2 in stroma is associated with recurrent basal-like breast cancers.
Min Yao, Elaine Yu, +2 authors, Nikki Cheng.
Mod Pathol, 2016 Apr 30; 29(8). PMID: 27125354
Additional Value of Diffusion-Weighted Imaging to Evaluate Prognostic Factors of Breast Cancer: Correlation with the Apparent Diffusion Coefficient.
Eun Kyung Park, Kyu Ran Cho, +3 authors, Jeoung Won Bae.
Iran J Radiol, 2016 Apr 30; 13(1). PMID: 27127582    Free PMC article.
Value of Breast Cancer Molecular Subtypes and Ki67 Expression for the Prediction of Efficacy and Prognosis of Neoadjuvant Chemotherapy in a Chinese Population.
Jiayu Wang, Die Sang, +9 authors, Qiao Li.
Medicine (Baltimore), 2016 May 07; 95(18). PMID: 27149453    Free PMC article.
Optimal Ki67 cut-off for luminal breast cancer prognostic evaluation: a large case series study with a long-term follow-up.
Sara Bustreo, Simona Osella-Abate, +6 authors, Isabella Castellano.
Breast Cancer Res Treat, 2016 May 09; 157(2). PMID: 27155668    Free PMC article.
TransCONFIRM: Identification of a Genetic Signature of Response to Fulvestrant in Advanced Hormone Receptor-Positive Breast Cancer.
Rinath Jeselsohn, William T Barry, +10 authors, Luca Malorni.
Clin Cancer Res, 2016 Nov 01; 22(23). PMID: 27185372    Free PMC article.
Neoadjuvant Sequential Docetaxel Followed by High-Dose Epirubicin in Combination With Cyclophosphamide Administered Concurrently With Trastuzumab. The DECT Trial.
Laura Pizzuti, Maddalena Barba, +18 authors, Patrizia Vici.
J Cell Physiol, 2016 May 18; 231(11). PMID: 27187274    Free PMC article.
Intravoxel incoherent motion diffusion-weighted MR imaging of breast cancer: association with histopathological features and subtypes.
Yunju Kim, Kyounglan Ko, +4 authors, Boram Park.
Br J Radiol, 2016 May 21; 89(1063). PMID: 27197744    Free PMC article.
High prevalence of luminal B breast cancer intrinsic subtype in Colombian women.
Silvia Juliana Serrano-Gomez, Maria Carolina Sanabria-Salas, +7 authors, Jovanny Zabaleta.
Carcinogenesis, 2016 May 22; 37(7). PMID: 27207651    Free PMC article.
Characteristics and survival of patients with metachronous or synchronous double primary malignancies: breast and thyroid cancer.
Li Zhang, Yansheng Wu, +2 authors, Zhongsheng Tong.
Oncotarget, 2016 May 26; 7(32). PMID: 27223440    Free PMC article.
HER2 reduces breast cancer radiosensitivity by activating focal adhesion kinase in vitro and in vivo.
Jing Hou, Zhirui Zhou, +8 authors, Xiaomao Guo.
Oncotarget, 2016 Jun 11; 7(29). PMID: 27286256    Free PMC article.
Extent of ductal carcinoma in situ according to breast cancer subtypes: a population-based cohort study.
Shusma C Doebar, Esther C van den Broek, +4 authors, Carolien H M van Deurzen.
Breast Cancer Res Treat, 2016 Jun 20; 158(1). PMID: 27318854    Free PMC article.
Tumor suppressor berberine binds VASP to inhibit cell migration in basal-like breast cancer.
Ke Su, Pengchao Hu, +7 authors, Jingwei Zhang.
Oncotarget, 2016 Jun 21; 7(29). PMID: 27322681    Free PMC article.
Prognostic value of the ubiquitin ligase carboxyl terminus of the Hsc70-interacting protein in postmenopausal breast cancer.
Sasagu Kurozumi, Yuri Yamaguchi, +9 authors, Masafumi Kurosumi.
Cancer Med, 2016 Jun 24; 5(8). PMID: 27334118    Free PMC article.
Early breast cancer screening using iron/iron oxide-based nanoplatforms with sub-femtomolar limits of detection.
Dinusha N Udukala, Hongwang Wang, +19 authors, Stefan H Bossmann.
Beilstein J Nanotechnol, 2016 Jun 24; 7. PMID: 27335730    Free PMC article.
Extensive Transcriptomic and Genomic Analysis Provides New Insights about Luminal Breast Cancers.
Inna Tishchenko, Heloisa Helena Milioli, Carlos Riveros, Pablo Moscato.
PLoS One, 2016 Jun 25; 11(6). PMID: 27341628    Free PMC article.
The dual role of FOXF2 in regulation of DNA replication and the epithelial-mesenchymal transition in breast cancer progression.
Pang-Kuo Lo, Ji Shin Lee, Xiaohui Liang, Saraswati Sukumar.
Cell Signal, 2016 Jul 06; 28(10). PMID: 27377963    Free PMC article.
Technical validation of an RT-qPCR in vitro diagnostic test system for the determination of breast cancer molecular subtypes by quantification of ERBB2, ESR1, PGR and MKI67 mRNA levels from formalin-fixed paraffin-embedded breast tumor specimens.
Mark Laible, Kornelia Schlombs, +8 authors, Ugur Sahin.
BMC Cancer, 2016 Jul 09; 16. PMID: 27389414    Free PMC article.
Cancer Hallmarks, Biomarkers and Breast Cancer Molecular Subtypes.
Xiaofeng Dai, Liangjian Xiang, Ting Li, Zhonghu Bai.
J Cancer, 2016 Jul 09; 7(10). PMID: 27390604    Free PMC article.
Highly Cited. Review.
Non-canonical NF-κB pathway activation predicts outcome in borderline oestrogen receptor positive breast carcinoma.
Federico Rojo, Abel González-Pérez, +15 authors, Pilar Eroles.
Br J Cancer, 2016 Jul 13; 115(3). PMID: 27404455    Free PMC article.
Outcome Disparities in African American Compared with European American Women with ER+HER2- Tumors Treated within an Equal-Access Health Care System.
Nicholas S Costantino, Benjamin Freeman, Craig D Shriver, Rachel E Ellsworth.
Ethn Dis, 2016 Jul 22; 26(3). PMID: 27440982    Free PMC article.
Prognostic impact of AJCC response criteria for neoadjuvant chemotherapy in stage II/III breast cancer patients: breast cancer subtype analyses.
Yaewon Yang, Seock-Ah Im, +11 authors, Dong-Young Noh.
BMC Cancer, 2016 Jul 23; 16. PMID: 27444430    Free PMC article.
Metabolomics of Breast Cancer Using High-Resolution Magic Angle Spinning Magnetic Resonance Spectroscopy: Correlations with 18F-FDG Positron Emission Tomography-Computed Tomography, Dynamic Contrast-Enhanced and Diffusion-Weighted Imaging MRI.
Haesung Yoon, Dahye Yoon, +9 authors, Min Jung Kim.
PLoS One, 2016 Jul 28; 11(7). PMID: 27459480    Free PMC article.
The highly expressed 5'isomiR of hsa-miR-140-3p contributes to the tumor-suppressive effects of miR-140 by reducing breast cancer proliferation and migration.
Omar Salem, Nese Erdem, +5 authors, Cindy Körner.
BMC Genomics, 2016 Aug 10; 17. PMID: 27502506    Free PMC article.
Histogram analysis of apparent diffusion coefficients after neoadjuvant chemotherapy in breast cancer.
Yun Ju Kim, Sung Hun Kim, +3 authors, Byung Joo Song.
Jpn J Radiol, 2016 Aug 16; 34(10). PMID: 27517370
The Relationship Between Estrogen Receptor, Progesterone Receptor and Human Epidermal Growth Factor Receptor 2 Expression of Breast Cancer and the Retention Index in Dual Phase (18)F-FDG PET/CT.
Hansol Moon, Woo Chul Noh, +10 authors, Sang Moo Lim.
Nucl Med Mol Imaging, 2016 Aug 20; 50(3). PMID: 27540429    Free PMC article.
Luminal B breast cancer: patterns of recurrence and clinical outcome.
Zhi-Hua Li, Ping-Hua Hu, Jian-Hong Tu, Ni-Si Yu.
Oncotarget, 2016 Aug 20; 7(40). PMID: 27542253    Free PMC article.
Young Age Is Associated with Increased Locoregional Recurrence in Node-Positive Breast Cancer with Luminal Subtypes.
Sang-Won Kim, Mison Chun, +5 authors, Seung Hee Kang.
Cancer Res Treat, 2016 Aug 25; 49(2). PMID: 27554479    Free PMC article.
Efficacy of Letrozole as First-Line Treatment of Postmenopausal Women with Hormone Receptor-Positive Metastatic Breast Cancer in Korea.
Seung Hoon Beom, Jisu Oh, +10 authors, Seock-Ah Im.
Cancer Res Treat, 2016 Aug 25; 49(2). PMID: 27554482    Free PMC article.
Identification of breast cancer cell subtypes sensitive to ATG4B inhibition.
Svetlana Bortnik, Courtney Choutka, +9 authors, Sharon M Gorski.
Oncotarget, 2016 Aug 25; 7(41). PMID: 27556700    Free PMC article.
Hypofractionation with no boost after breast conservation in early-stage breast cancer patients.
Francesca Arcadipane, Pierfrancesco Franco, +11 authors, Umberto Ricardi.
Med Oncol, 2016 Aug 31; 33(10). PMID: 27573380
From High-Throughput Microarray-Based Screening to Clinical Application: The Development of a Second Generation Multigene Test for Breast Cancer Prognosis.
Jan C Brase, Ralf Kronenwett, +2 authors, Marcus Schmidt.
Microarrays (Basel), 2013 Jan 01; 2(3). PMID: 27605191    Free PMC article.
Review.
Prognostic values of negative estrogen or progesterone receptor expression in patients with luminal B HER2-negative breast cancer.
Chansub Park, Kyeongmee Park, +8 authors, Geumhee Gwak.
World J Surg Oncol, 2016 Sep 14; 14(1). PMID: 27619909    Free PMC article.
Prognosis of breast cancer molecular subtypes in routine clinical care: A large prospective cohort study.
André Hennigs, Fabian Riedel, +13 authors, Andreas Schneeweiss.
BMC Cancer, 2016 Sep 17; 16(1). PMID: 27634735    Free PMC article.
[New prognostic and predictive markers for breast cancer].
D L Wachter.
Pathologe, 2016 Sep 18; 37(Suppl 2). PMID: 27638528
Review.
αB-crystallin Expression in Breast Cancer is Associated with Brain Metastasis.
K David Voduc, Torsten O Nielsen, +6 authors, Maggie C U Cheang.
NPJ Breast Cancer, 2016 Sep 23; 1. PMID: 27656679    Free PMC article.
Comparison of the Ability of Different Clinical Treatment Scores to Estimate Prognosis in High-Risk Early Breast Cancer Patients: A Hellenic Cooperative Oncology Group Study.
Flora Stavridi, Konstantine T Kalogeras, +19 authors, George Fountzilas.
PLoS One, 2016 Oct 04; 11(10). PMID: 27695115    Free PMC article.
Decreased sirtuin 4 expression is associated with poor prognosis in patients with invasive breast cancer.
Qingyu Shi, Tong Liu, +4 authors, Da Pang.
Oncol Lett, 2016 Oct 05; 12(4). PMID: 27698834    Free PMC article.
Transcriptomic characterization of differential gene expression in oral squamous cell carcinoma: a meta-analysis of publicly available microarray data sets.
Yang Sun, Zhijian Sang, +2 authors, Youcheng Yu.
Tumour Biol, 2016 Oct 06;. PMID: 27704359
Biological Subtypes and Distant Relapse Pattern in Breast Cancer Patients After Curative Surgery (Study of Anatolian Society of Medical Oncology).
Muhammet A Kaplan, Ulku Y Arslan, +21 authors, Mukremin Uysal.
Breast Care (Basel), 2016 Oct 11; 11(4). PMID: 27721711    Free PMC article.
Low Ki67/high ATM protein expression in malignant tumors predicts favorable prognosis in a retrospective study of early stage hormone receptor positive breast cancer.
Xiaolan Feng, Haocheng Li, +9 authors, Alexander Paterson.
Oncotarget, 2016 Oct 16; 7(52). PMID: 27741524    Free PMC article.
Magnetic resonance imaging and pathological characteristics of pure mucinous carcinoma in the breast according to echogenicity on ultrasonography.
Young Gyung Shin, Eun-Kyung Kim, +2 authors, Hee Jung Moon.
Ultrasonography, 2016 Oct 22; 36(2). PMID: 27764910    Free PMC article.
Correlating Tumor Stiffness with Immunohistochemical Subtypes of Breast Cancers: Prognostic Value of Comb-Push Ultrasound Shear Elastography for Differentiating Luminal Subtypes.
Max Denis, Adriana Gregory, +6 authors, Azra Alizad.
PLoS One, 2016 Oct 25; 11(10). PMID: 27776153    Free PMC article.
Steroid Hormone Receptor Positive Breast Cancer Patient-Derived Xenografts.
Shawna B Matthews, Carol A Sartorius.
Horm Cancer, 2016 Nov 01; 8(1). PMID: 27796944    Free PMC article.
Review.
Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer.
Gabriele Corda, Gianluca Sala, +22 authors, Arturo Sala.
J Pathol, 2016 Nov 20; 241(3). PMID: 27859262    Free PMC article.
Unique epigenetic gene profiles define human breast cancers with poor prognosis.
Samuel Peña-Llopis, Yihong Wan, Elisabeth D Martinez.
Oncotarget, 2016 Nov 20; 7(52). PMID: 27863398    Free PMC article.
Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer.
Kelly K Hunt, Cansu Karakas, +13 authors, Khandan Keyomarsi.
Clin Cancer Res, 2016 Nov 25; 23(12). PMID: 27881578    Free PMC article.
Oestrogen receptor negativity in breast cancer: a cause or consequence?
Vijaya Narasihma Reddy Gajulapalli, Vijaya Lakshmi Malisetty, Suresh Kumar Chitta, Bramanandam Manavathi.
Biosci Rep, 2016 Nov 26; 36(6). PMID: 27884978    Free PMC article.
Review.
CD44 induces FOXP3 expression and is related with favorable outcome in breast carcinoma.
Elena Sanmartín, Fernando Ortiz-Martínez, +9 authors, Gloria Peiró.
Virchows Arch, 2016 Nov 26; 470(1). PMID: 27885422
Identification of lncRNA FAM83H-AS1 as a novel prognostic marker in luminal subtype breast cancer.
Fan Yang, Shi-Xu Lv, +6 authors, Ou-Chen Wang.
Onco Targets Ther, 2016 Nov 30; 9. PMID: 27895496    Free PMC article.
Androgen Receptor: A Complex Therapeutic Target for Breast Cancer.
Ramesh Narayanan, James T Dalton.
Cancers (Basel), 2016 Dec 06; 8(12). PMID: 27918430    Free PMC article.
Review.
Homeobox A11 hypermethylation indicates unfavorable prognosis in breast cancer.
Bingshu Xia, Ming Shan, +6 authors, Da Pang.
Oncotarget, 2016 Dec 31; 8(6). PMID: 28038461    Free PMC article.
Claudin-Low Breast Cancer; Clinical & Pathological Characteristics.
Kay Dias, Anna Dvorkin-Gheva, +6 authors, Anita L Bane.
PLoS One, 2017 Jan 04; 12(1). PMID: 28045912    Free PMC article.
Prognostic significance of Ki67 in Chinese women diagnosed with ER+/HER2- breast cancers by the 2015 St. Gallen consensus classification.
Yue Hu, Ran Gu, +9 authors, Weijuan Jia.
BMC Cancer, 2017 Jan 08; 17(1). PMID: 28061893    Free PMC article.
Algorithms for prediction of the Oncotype DX recurrence score using clinicopathologic data: a review and comparison using an independent dataset.
Michael R Harowicz, Timothy J Robinson, +4 authors, Maciej A Mazurowski.
Breast Cancer Res Treat, 2017 Jan 09; 162(1). PMID: 28064383    Free PMC article.
First report on molecular breast cancer subtypes and their clinico-pathological characteristics in Eastern Morocco: series of 2260 cases.
Manal Elidrissi Errahhali, Mounia Elidrissi Errahhali, +3 authors, Mohammed Bellaoui.
BMC Womens Health, 2017 Jan 11; 17(1). PMID: 28068979    Free PMC article.
P-cadherin: a useful biomarker for axillary-based breast cancer decisions in the clinical practice.
André Filipe Vieira, Maria Rita Dionísio, +5 authors, Joana Paredes.
Mod Pathol, 2017 Jan 14; 30(5). PMID: 28084338
MCM2: An alternative to Ki-67 for measuring breast cancer cell proliferation.
Einas M Yousef, Daniela Furrer, +4 authors, Louis A Gaboury.
Mod Pathol, 2017 Jan 14; 30(5). PMID: 28084344
Estimation of T2* Relaxation Time of Breast Cancer: Correlation with Clinical, Imaging and Pathological Features.
Mirinae Seo, Jung Kyu Ryu, +4 authors, Kyu-Yeoun Won.
Korean J Radiol, 2017 Jan 18; 18(1). PMID: 28096732    Free PMC article.
BI-RADS 3-5 microcalcifications can preoperatively predict breast cancer HER2 and Luminal a molecular subtype.
DongZhi Cen, Li Xu, +7 authors, Tingting Luo.
Oncotarget, 2017 Jan 19; 8(8). PMID: 28099938    Free PMC article.
Molecular characterization of CD44+/CD24-/Ck+/CD45- cells in benign and malignant breast lesions.
Arnaud Da Cruz Paula, Catarina Leitão, +8 authors, Carlos Lopes.
Virchows Arch, 2017 Jan 25; 470(3). PMID: 28116522
CDH22 hypermethylation is an independent prognostic biomarker in breast cancer.
Esperanza Martín-Sánchez, Saioa Mendaza, +7 authors, David Guerrero-Setas.
Clin Epigenetics, 2017 Feb 06; 9. PMID: 28149335    Free PMC article.
Ki-67 as a prognostic marker according to breast cancer molecular subtype.
Nahed A Soliman, Shaimaa M Yussif.
Cancer Biol Med, 2017 Feb 06; 13(4). PMID: 28154782    Free PMC article.
Radiomic analysis reveals DCE-MRI features for prediction of molecular subtypes of breast cancer.
Ming Fan, Hui Li, +3 authors, Lihua Li.
PLoS One, 2017 Feb 07; 12(2). PMID: 28166261    Free PMC article.
CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer.
Esperanza Martín-Sánchez, Saioa Mendaza, +11 authors, David Guerrero-Setas.
Oncotarget, 2017 Feb 09; 8(9). PMID: 28178655    Free PMC article.
How interacting pathways are regulated by miRNAs in breast cancer subtypes.
Claudia Cava, Antonio Colaprico, +3 authors, Isabella Castiglioni.
BMC Bioinformatics, 2017 Feb 12; 17(Suppl 12). PMID: 28185585    Free PMC article.
A comparison of Ki-67 counting methods in luminal Breast Cancer: The Average Method vs. the Hot Spot Method.
Min Hye Jang, Hyun Jung Kim, +2 authors, So Yeon Park.
PLoS One, 2017 Feb 12; 12(2). PMID: 28187177    Free PMC article.
Comparison of immunohistochemistry with PCR for assessment of ER, PR, and Ki-67 and prediction of pathological complete response in breast cancer.
Hans-Peter Sinn, Andreas Schneeweiss, +9 authors, Frederik Marmé.
BMC Cancer, 2017 Feb 15; 17(1). PMID: 28193205    Free PMC article.
Association of osteopontin with specific prognostic factors and survival in adjuvant breast cancer trials of the Hellenic Cooperative Oncology Group.
Amanda Psyrri, Konstantine T Kalogeras, +21 authors, George Fountzilas.
J Transl Med, 2017 Feb 15; 15(1). PMID: 28193231    Free PMC article.
[Breast cancer in Morocco: phenotypic profile of tumors].
Ahmadaye Ibrahim Khalil, Karima Bendahhou, +2 authors, Abdellatif Benider.
Pan Afr Med J, 2017 Mar 16; 25. PMID: 28292037    Free PMC article.
A phase II study of combined ridaforolimus and dalotuzumab compared with exemestane in patients with estrogen receptor-positive breast cancer.
José Baselga, Serafin M Morales, +17 authors, Hope S Rugo.
Breast Cancer Res Treat, 2017 Mar 23; 163(3). PMID: 28324268    Free PMC article.
Cinical Significance of Androgen Receptor, CK-5/6, KI-67 and Molecular Subtypes in Breast Cancer.
Münire Kayahan, Ufuk Oğuz İdiz, +3 authors, Mahmut Müslümanoğlu.
J Breast Health, 2014 Jan 01; 10(4). PMID: 28331672    Free PMC article.
Molecular Classification of Breast Carcinoma: From Traditional, Old-Fashioned Way to A New Age, and A New Way.
Nuket Eliyatkın, Evrim Yalçın, +2 authors, Enver Vardar.
J Breast Health, 2015 Jan 01; 11(2). PMID: 28331693    Free PMC article.
Review.
Differential impact of hormone receptor status on survival and recurrence for HER2 receptor-positive breast cancers treated with Trastuzumab.
Andrew McGuire, Olga Kalinina, +6 authors, Michael J Kerin.
Breast Cancer Res Treat, 2017 Apr 06; 164(1). PMID: 28378298    Free PMC article.
Differences in subtype distribution between screen-detected and symptomatic invasive breast cancer and their impact on survival.
N Kobayashi, M Hikichi, +4 authors, T Utsumi.
Clin Transl Oncol, 2017 Apr 15; 19(10). PMID: 28409323
Immunohistochemical Ki67 after short-term hormone therapy identifies low-risk breast cancers as reliably as genomic markers.
Takayuki Iwamoto, Toyomasa Katagiri, +12 authors, Junji Matsuoka.
Oncotarget, 2017 Apr 17; 8(16). PMID: 28412725    Free PMC article.
Effect of Ki-67 assessment in the distribution of breast cancer subtypes: Evaluation in a cohort of Latin American patients.
Alejandro Yábar, Rosa Meléndez, +6 authors, Raúl E Velarde-López.
Mol Clin Oncol, 2017 Apr 18; 6(4). PMID: 28413656    Free PMC article.
Phosphorylation of androgen receptors at serine 515 is a potential prognostic marker for triple negative breast cancer.
Antonia K Roseweir, Pamela McCall, +4 authors, Joanne Edwards.
Oncotarget, 2017 Apr 19; 8(23). PMID: 28415597    Free PMC article.
Mitotic read-out genes confer poor outcome in luminal A breast cancer tumors.
Javier Pérez-Peña, Ana Alcaraz-Sanabria, +9 authors, Alberto Ocaña.
Oncotarget, 2017 Apr 21; 8(13). PMID: 28423514    Free PMC article.
Limitations in predicting PAM50 intrinsic subtype and risk of relapse score with Ki67 in estrogen receptor-positive HER2-negative breast cancer.
Aranzazu Fernandez-Martinez, Tomás Pascual, +30 authors, Miguel Martin.
Oncotarget, 2017 Apr 21; 8(13). PMID: 28423537    Free PMC article.
Quantification of HER2 and estrogen receptor heterogeneity in breast cancer by single-molecule RNA fluorescence in situ hybridization.
Laura Annaratone, Michele Simonetti, +7 authors, Nicola Crosetto.
Oncotarget, 2017 Apr 21; 8(12). PMID: 28423635    Free PMC article.
Post-operative radiotherapy is beneficial for T1/T2 triple negative breast cancer patients with four or more positive lymph nodes.
Lin Chen, Jinfeng Zhang, +4 authors, Dandan Wang.
Oncotarget, 2017 May 06; 8(26). PMID: 28476034    Free PMC article.
Ki67 expression in invasive breast cancer: the use of tissue microarrays compared with whole tissue sections.
Abir A Muftah, Mohammed A Aleskandarany, +7 authors, Andrew R Green.
Breast Cancer Res Treat, 2017 May 10; 164(2). PMID: 28478613    Free PMC article.
Quality assurance trials for Ki67 assessment in pathology.
M Raap, S Ließem, +5 authors, H Kreipe.
Virchows Arch, 2017 May 13; 471(4). PMID: 28497316
Clinical utility of gene-expression signatures in early stage breast cancer.
Maryann Kwa, Andreas Makris, Francisco J Esteva.
Nat Rev Clin Oncol, 2017 Jun 01; 14(10). PMID: 28561071
Highly Cited. Review.
Molecular characterization of breast cancer cell lines by clinical immunohistochemical markers.
André de Lima Mota, Adriane Feijo Evangelista, +4 authors, Marcia Maria Chiquitelli Marques.
Oncol Lett, 2017 Jun 08; 13(6). PMID: 28588725    Free PMC article.
Development of a Ki-67-based clinical trial assay for neoadjuvant endocrine therapy response monitoring in breast cancer.
Rodrigo Goncalves, Katherine DeSchryver, +11 authors, Matthew J Ellis.
Breast Cancer Res Treat, 2017 Jun 15; 165(2). PMID: 28612227    Free PMC article.
Survivin expression pattern in the intestine of normoxic and ischemic rats.
Alexandra Scheer, Shirley K Knauer, Rabea Verhaegh.
BMC Gastroenterol, 2017 Jun 16; 17(1). PMID: 28615071    Free PMC article.
Evaluation of the Prognostic Value of RANK, OPG, and RANKL mRNA Expression in Early Breast Cancer Patients Treated with Anthracycline-Based Adjuvant Chemotherapy.
Eleni Timotheadou, Konstantine T Kalogeras, +16 authors, George Fountzilas.
Transl Oncol, 2017 Jul 01; 10(4). PMID: 28666187    Free PMC article.
PAM50 gene signatures and breast cancer prognosis with adjuvant anthracycline- and taxane-based chemotherapy: correlative analysis of C9741 (Alliance).
Minetta C Liu, Brandelyn N Pitcher, +20 authors, William T Barry.
NPJ Breast Cancer, 2016 Jan 01; 2. PMID: 28691057    Free PMC article.
[18F]FDG PET/CT features for the molecular characterization of primary breast tumors.
Lidija Antunovic, Francesca Gallivanone, +7 authors, Isabella Castiglioni.
Eur J Nucl Med Mol Imaging, 2017 Jul 18; 44(12). PMID: 28711994
The Epigenetic Landscape of Promoter Genome-wide Analysis in Breast Cancer.
Seher Karsli-Ceppioglu, Aslihan Dagdemir, +4 authors, Dominique Bernard-Gallon.
Sci Rep, 2017 Jul 28; 7(1). PMID: 28747748    Free PMC article.
Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: oncogenic rather than tumor-suppressive role of E-cadherin.
H J Hugo, N P A D Gunasinghe, +7 authors, E W Thompson.
Breast Cancer Res, 2017 Jul 29; 19(1). PMID: 28750639    Free PMC article.
Integrated diagnostic network construction reveals a 4-gene panel and 5 cancer hallmarks driving breast cancer heterogeneity.
Xiaofeng Dai, Tongyan Hua, Tingting Hong.
Sci Rep, 2017 Jul 30; 7(1). PMID: 28754978    Free PMC article.
Ganoderma spp.: A Promising Adjuvant Treatment for Breast Cancer.
Ivette J Suárez-Arroyo, Yaliz Loperena-Alvarez, Raysa Rosario-Acevedo, Michelle M Martínez-Montemayor.
Medicines (Basel), 2017 Aug 02; 4(1). PMID: 28758107    Free PMC article.
Stathmin1 expression is associated with aggressive phenotypes and cancer stem cell marker expression in breast cancer patients.
Sayaka Obayashi, Jun Horiguchi, +10 authors, Hiroyuki Kuwano.
Int J Oncol, 2017 Aug 03; 51(3). PMID: 28766688    Free PMC article.
Percentage change of primary tumor on 18F-FDG PET/CT as a prognostic factor for invasive ductal breast cancer with axillary lymph node metastasis: Comparison with MRI.
Jang Yoo, Bom Sahn Kim, Jin Chung, Hai-Jeon Yoon.
Medicine (Baltimore), 2017 Aug 03; 96(31). PMID: 28767583    Free PMC article.
Tumor infiltrating leukocyte density is independent of tumor grade and molecular subtype in aggressive breast cancer of Western Kenya.
Rispah T Sawe, Simeon K Mining, +11 authors, Laurie E Littlepage.
Trop Med Health, 2017 Aug 11; 45. PMID: 28794686    Free PMC article.
Protein expression patterns of cell cycle regulators in operable breast cancer.
Flora Zagouri, Vassiliki Kotoula, +21 authors, George Fountzilas.
PLoS One, 2017 Aug 11; 12(8). PMID: 28797035    Free PMC article.
Breast cancer subtype discrimination using standardized 4-IHC and digital image analysis.
Marina Gándara-Cortes, Ángel Vázquez-Boquete, +10 authors, Tomás García-Caballero.
Virchows Arch, 2017 Aug 22; 472(2). PMID: 28825136
Ancestry as a potential modifier of gene expression in breast tumors from Colombian women.
Silvia J Serrano-Gómez, María Carolina Sanabria-Salas, +7 authors, Jovanny Zabaleta.
PLoS One, 2017 Aug 24; 12(8). PMID: 28832682    Free PMC article.
Decreasing Eukaryotic Initiation Factor 3C (EIF3C) Suppresses Proliferation and Stimulates Apoptosis in Breast Cancer Cell Lines Through Mammalian Target of Rapamycin (mTOR) Pathway.
Weipeng Zhao, Xichuan Li, +6 authors, Zhongsheng Tong.
Med Sci Monit, 2017 Aug 31; 23. PMID: 28854163    Free PMC article.
Ki-67 Expression in Breast Cancer Tissue Microarrays: Assessing Tumor Heterogeneity, Concordance With Full Section, and Scoring Methods.
Thaer Khoury, Gary Zirpoli, +9 authors, Christine B Ambrosone.
Am J Clin Pathol, 2017 Sep 14; 148(2). PMID: 28898983    Free PMC article.
Splice variants of cytosolic polyadenylation element-binding protein 2 (CPEB2) differentially regulate pathways linked to cancer metastasis.
James T DeLigio, Grace Lin, Charles E Chalfant, Margaret A Park.
J Biol Chem, 2017 Sep 15; 292(43). PMID: 28904175    Free PMC article.
The Impact of Young Age for Prognosis by Subtype in Women with Early Breast Cancer.
Weibin Lian, Fangmeng Fu, +6 authors, Chuan Wang.
Sci Rep, 2017 Sep 16; 7(1). PMID: 28912475    Free PMC article.
Therapeutic Implications of the Molecular and Immune Landscape of Triple-Negative Breast Cancer.
Ana C Gregório, Manuela Lacerda, +3 authors, João Nuno Moreira.
Pathol Oncol Res, 2017 Sep 16; 24(4). PMID: 28913723
Review.
Epigenetic Mechanisms of Tamoxifen Resistance in Luminal Breast Cancer.
Hany A Abdel-Hafiz.
Diseases, 2017 Sep 22; 5(3). PMID: 28933369    Free PMC article.
Review.
Texture analysis of high-resolution dedicated breast 18 F-FDG PET images correlates with immunohistochemical factors and subtype of breast cancer.
Alexis Moscoso, Álvaro Ruibal, +7 authors, Pablo Aguiar.
Eur J Nucl Med Mol Imaging, 2017 Sep 25; 45(2). PMID: 28936601
Contrast Enhancement on Cone-Beam Breast-CT for Discrimination of Breast Cancer Immunohistochemical Subtypes.
Johannes Uhlig, Uwe Fischer, +4 authors, Susanne Wienbeck.
Transl Oncol, 2017 Sep 26; 10(6). PMID: 28946110    Free PMC article.
Cytoplasmic Cyclin E Mediates Resistance to Aromatase Inhibitors in Breast Cancer.
Iman Doostan, Cansu Karakas, +7 authors, Khandan Keyomarsi.
Clin Cancer Res, 2017 Sep 28; 23(23). PMID: 28947566    Free PMC article.
Clinical and pathological portraits of axillary presentation breast cancer and effects of preoperative systemic therapy.
Ling Xu, Fang Li, +4 authors, Ling Xin.
Chin J Cancer Res, 2017 Sep 28; 29(4). PMID: 28947869    Free PMC article.
Assessment of Ki67 and uPA/PAI-1 expression in intermediate-risk early stage breast cancers.
Elise Deluche, Laurence Venat-Bouvet, +6 authors, Nicole Tubiana-Mathieu.
BMC Cancer, 2017 Sep 29; 17(1). PMID: 28954632    Free PMC article.
Clinicopathological study of a dimorphic variant of breast carcinoma.
Nozomi Ueno, Hajime Kuroda, +5 authors, Yasuo Imai.
Breast Cancer, 2017 Oct 02; 25(2). PMID: 28965222    Free PMC article.
DNA-damage related genes and clinical outcome in hormone receptor positive breast cancer.
Cristina Nieto-Jiménez, Ana Alcaraz-Sanabria, +4 authors, Alberto Ocaña.
Oncotarget, 2016 Jul 28; 8(38). PMID: 28968952    Free PMC article.
Magnetic resonance metabolic profiling of estrogen receptor-positive breast cancer: correlation with currently used molecular markers.
Ji Soo Choi, Dahye Yoon, +5 authors, Min Jung Kim.
Oncotarget, 2017 Oct 04; 8(38). PMID: 28969000    Free PMC article.
Serum CA125 is a predictive marker for breast cancer outcomes and correlates with molecular subtypes.
Cheng Fang, Yue Cao, +2 authors, Yirong Li.
Oncotarget, 2017 Oct 04; 8(38). PMID: 28969044    Free PMC article.
High Eg5 expression predicts poor prognosis in breast cancer.
Qin Jin, Fang Huang, +5 authors, Qichao Ni.
Oncotarget, 2017 Oct 06; 8(37). PMID: 28977938    Free PMC article.
Prognostic immune-related gene models for breast cancer: a pooled analysis.
Jianli Zhao, Ying Wang, +6 authors, Kai Chen.
Onco Targets Ther, 2017 Oct 06; 10. PMID: 28979134    Free PMC article.
Male breast cancer: correlation between immunohistochemical subtyping and PAM50 intrinsic subtypes, and the subsequent clinical outcomes.
Alfonso Sánchez-Muñoz, Luis Vicioso, +12 authors, Emilio Alba.
Mod Pathol, 2017 Oct 07; 31(2). PMID: 28984296
Endocrine sensitivity of estrogen receptor-positive breast cancer is negatively correlated with aspartate-β-hydroxylase expression.
Masafumi Shimoda, Ami Hori, +8 authors, Shinzaburo Noguchi.
Cancer Sci, 2017 Oct 07; 108(12). PMID: 28985022    Free PMC article.
The value of phosphohistone H3 as a proliferation marker for evaluating invasive breast cancers: A comparative study with Ki67.
Ji-Ye Kim, Hyang Sook Jeong, +4 authors, Ja Seung Koo.
Oncotarget, 2017 Oct 17; 8(39). PMID: 29029412    Free PMC article.
ER-positive breast cancer patients with more than three positive nodes or grade 3 tumors are at high risk of late recurrence after 5-year adjuvant endocrine therapy.
Fangbin Song, Jianbing Zhang, +6 authors, Junming Xu.
Onco Targets Ther, 2017 Oct 19; 10. PMID: 29042797    Free PMC article.
Breast Cancer in Latinas: A Focus on Intrinsic Subtypes Distribution.
Silvia J Serrano-Gómez, Laura Fejerman, Jovanny Zabaleta.
Cancer Epidemiol Biomarkers Prev, 2017 Oct 22; 27(1). PMID: 29054978    Free PMC article.
Review.
Canine invasive mammary carcinomas as models of human breast cancer. Part 2: immunophenotypes and prognostic significance.
Jérôme Abadie, Frédérique Nguyen, +8 authors, Mario Campone.
Breast Cancer Res Treat, 2017 Oct 25; 167(2). PMID: 29063312    Free PMC article.
Ductal Carcinoma In Situ Biology, Biomarkers, and Diagnosis.
Kylie L Gorringe, Stephen B Fox.
Front Oncol, 2017 Nov 08; 7. PMID: 29109942    Free PMC article.
Review.
MicroRNA-10b expression in node-negative breast cancer-correlation with metastasis and angiogenesis.
Xia Liu, Yong Guan, Li Wang, Yun Niu.
Oncol Lett, 2017 Nov 09; 14(5). PMID: 29113216    Free PMC article.
Molecular Subtypes and Local-Regional Control of Breast Cancer.
Simona Maria Fragomeni, Andrew Sciallis, Jacqueline S Jeruss.
Surg Oncol Clin N Am, 2017 Nov 15; 27(1). PMID: 29132568    Free PMC article.
Review.
Ki67 Proliferation Index as a Histopathological Predictive and Prognostic Parameter of Oral Mucosal Melanoma in Patients without Distant Metastases.
Xuhui Ma, Yunteng Wu, +4 authors, Guoxin Ren.
J Cancer, 2017 Nov 21; 8(18). PMID: 29151970    Free PMC article.
Diffusion-weighted MRI characteristics associated with prognostic pathological factors and recurrence risk in invasive ER+/HER2- breast cancers.
Nita Amornsiripanitch, Vicky T Nguyen, +4 authors, Savannah C Partridge.
J Magn Reson Imaging, 2017 Nov 28; 48(1). PMID: 29178616    Free PMC article.
Application of artificial neural networks for predicting presence of non-sentinel lymph node metastases in breast cancer patients with positive sentinel lymph node biopsies.
Tomasz Nowikiewicz, Paweł Wnuk, +3 authors, Wojciech Zegarski.
Arch Med Sci, 2017 Nov 29; 13(6). PMID: 29181071    Free PMC article.
Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer.
Mónica Álvarez-Fernández, María Sanz-Flores, +11 authors, Marcos Malumbres.
Cell Death Differ, 2017 Dec 13; 25(5). PMID: 29229993    Free PMC article.
Entropy is a Simple Measure of the Antibody Profile and is an Indicator of Health Status: A Proof of Concept.
Lu Wang, Kurt Whittemore, Stephen Albert Johnston, Phillip Stafford.
Sci Rep, 2017 Dec 24; 7(1). PMID: 29273777    Free PMC article.
MRI texture analysis in differentiating luminal A and luminal B breast cancer molecular subtypes - a feasibility study.
Kirsi Holli-Helenius, Annukka Salminen, +4 authors, Riitta Parkkola.
BMC Med Imaging, 2017 Dec 30; 17(1). PMID: 29284425    Free PMC article.
Prognostic parameters of luminal A and luminal B intrinsic breast cancer subtypes of Pakistani patients.
Atif Ali Hashmi, Saher Aijaz, +8 authors, Amir Khan.
World J Surg Oncol, 2018 Jan 03; 16(1). PMID: 29291744    Free PMC article.
Frequent overexpression of AMAP1, an Arf6 effector in cell invasion, is characteristic of the MMTV-PyMT rather than the MMTV-Neu human breast cancer model.
Yutaro Otsuka, Tsukasa Oikawa, +5 authors, Hisataka Sabe.
Cell Commun Signal, 2018 Jan 14; 16(1). PMID: 29329590    Free PMC article.
microRNA-124 inhibits bone metastasis of breast cancer by repressing Interleukin-11.
Wei-Luo Cai, Wen-Ding Huang, +7 authors, Jian-Ru Xiao.
Mol Cancer, 2018 Jan 19; 17(1). PMID: 29343249    Free PMC article.
Prediction of low-risk breast cancer using quantitative DCE-MRI and its pathological basis.
Tingting Xu, Lin Zhang, +5 authors, Guangyu Tang.
Oncotarget, 2018 Jan 27; 8(69). PMID: 29371992    Free PMC article.
Molecular Subtypes of Indonesian Breast Carcinomas - Lack of Association with Patient Age and Tumor Size
Yeni Rahmawati, Yunita Setyawati, +2 authors, Dewajani Purnomosari.
Asian Pac J Cancer Prev, 2018 Jan 28; 19(1). PMID: 29373908    Free PMC article.
Frequency of breast cancer subtypes among African American women in the AMBER consortium.
Emma H Allott, Joseph Geradts, +24 authors, Melissa A Troester.
Breast Cancer Res, 2018 Feb 08; 20(1). PMID: 29409530    Free PMC article.
Prognostic impact of AnxA1 and AnxA2 gene expression in triple-negative breast cancer.
Lee D Gibbs, Jamboor K Vishwanatha.
Oncotarget, 2018 Feb 09; 9(2). PMID: 29416802    Free PMC article.
Targeting breast cancer cells with a CuInS2/ZnS quantum dot-labeled Ki-67 bioprobe.
Guang Sun, Wanying Xing, +3 authors, Siyao Yu.
Oncol Lett, 2018 Feb 13; 15(2). PMID: 29434960    Free PMC article.
Significance of lung biopsy for the definitive diagnosis of lung nodules in breast cancer patients.
Kazuo Matsuura, Toshiyuki Itamoto, +7 authors, Morihito Okada.
Mol Clin Oncol, 2018 Feb 13; 8(2). PMID: 29435285    Free PMC article.
A Metabolomic Approach to Predict Breast Cancer Behavior and Chemotherapy Response.
Marcella Regina Cardoso, Juliana Carvalho Santos, +3 authors, Sophie Françoise Mauricette Derchain.
Int J Mol Sci, 2018 Feb 22; 19(2). PMID: 29466297    Free PMC article.
Review.
Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation.
Mustapha Abubakar, Jenny Chang-Claude, +34 authors, Montserrat Garcia-Closas.
Int J Cancer, 2018 Mar 02; 143(4). PMID: 29492969    Free PMC article.
Association between enhancement patterns and parameters of contrast-enhanced ultrasound and microvessel distribution in breast cancer.
Xiaokang Li, Yaqing Li, +2 authors, Peifang Liu.
Oncol Lett, 2018 Mar 21; 15(4). PMID: 29556301    Free PMC article.
DCE-MRI Pharmacokinetic-Based Phenotyping of Invasive Ductal Carcinoma: A Radiomic Study for Prediction of Histological Outcomes.
Serena Monti, Marco Aiello, +6 authors, Marco Salvatore.
Contrast Media Mol Imaging, 2018 Mar 28; 2018. PMID: 29581709    Free PMC article.
microRNA-10b expression and its correlation with molecular subtypes of early invasive ductal carcinoma.
Chenming Guo, Minggang Fu, +2 authors, Liying Guo.
Exp Ther Med, 2018 Mar 31; 15(3). PMID: 29599829    Free PMC article.
Use of the tumor-infiltrating CD8 to FOXP3 lymphocyte ratio in predicting treatment responses to combination therapy with pertuzumab, trastuzumab, and docetaxel for advanced HER2-positive breast cancer.
Koji Takada, Shinichiro Kashiwagi, +7 authors, Masaichi Ohira.
J Transl Med, 2018 Apr 05; 16(1). PMID: 29615076    Free PMC article.
Diagnostic and prognostic values of contrast‑enhanced ultrasound combined with diffusion‑weighted magnetic resonance imaging in different subtypes of breast cancer.
Gui-Feng Liu, Zong-Qiang Wang, +4 authors, Shao-Nan Yu.
Int J Mol Med, 2018 Apr 06; 42(1). PMID: 29620140    Free PMC article.
Does Methodological Guidance Produce Consistency? A Review of Methodological Consistency in Breast Cancer Utility Value Measurement in NICE Single Technology Appraisals.
Micah Rose, Stephen Rice, Dawn Craig.
Pharmacoecon Open, 2018 Apr 07; 2(2). PMID: 29623616    Free PMC article.
Review.
Reduced expression of α-L-Fucosidase-1 (FUCA-1) predicts recurrence and shorter cancer specific survival in luminal B LN+ breast cancer patients.
Serena Bonin, Alessia Parascandolo, +5 authors, Giancarlo Vecchio.
Oncotarget, 2018 Apr 11; 9(20). PMID: 29632639    Free PMC article.
ANP32E induces tumorigenesis of triple-negative breast cancer cells by upregulating E2F1.
Zhenchong Xiong, Liping Ye, +9 authors, Xi Wang.
Mol Oncol, 2018 Apr 11; 12(6). PMID: 29633513    Free PMC article.
Patterns of breast cancer relapse in accordance to biological subtype.
Atanas Ignatov, Holm Eggemann, Elke Burger, Tanja Ignatov.
J Cancer Res Clin Oncol, 2018 Apr 21; 144(7). PMID: 29675790
Proliferative Index (Ki67) for Prediction in Breast Duct Carcinomas
Shatha Th Ahmed, Azad M Ahmed, +3 authors, Intisar S Pity.
Asian Pac J Cancer Prev, 2018 Apr 26; 19(4). PMID: 29693354    Free PMC article.
Diffusion tensor magnetic resonance imaging of breast cancer: associations between diffusion metrics and histological prognostic factors.
Jin You Kim, Jin Joo Kim, +4 authors, Heesung Park.
Eur Radiol, 2018 May 02; 28(8). PMID: 29713771
Association of APEX1 and OGG1 gene polymorphisms with breast cancer risk among Han women in the Gansu Province of China.
Tao Wang, Haitao Wang, +10 authors, Haixiang Su.
BMC Med Genet, 2018 May 04; 19(1). PMID: 29720094    Free PMC article.
Practical consensus recommendations on management of HR + ve early breast cancer with specific reference to genomic profiling.
S Aggarwal, A Vaid, +10 authors, D Doval.
South Asian J Cancer, 2018 May 04; 7(2). PMID: 29721472    Free PMC article.
Prognostic Significance of Reduction in Ki67 Index After Neoadjuvant Chemotherapy in Patients With Breast Cancer in Kerman Between 2009 And 2014.
Vahid Moazed, Elham Jafari, +3 authors, Seyyed Amir Ben Razavi.
Iran J Pathol, 2018 May 08; 13(1). PMID: 29731798    Free PMC article.
Identification of copy number alterations in colon cancer from analysis of amplicon-based next generation sequencing data.
Duarte Mendes Oliveira, Gianluca Santamaria, +13 authors, Antonia Rizzuto.
Oncotarget, 2018 May 15; 9(29). PMID: 29755661    Free PMC article.
Effect of neoadjuvant chemotherapy on the expression of hormone receptors and Ki-67 in Chinese breast cancer patients: A retrospective study of 525 patients.
Yu-Tuan Wu, Xin Li, +6 authors, Ling-Quan Kong.
J Biomed Res, 2018 May 18;. PMID: 29770779    Free PMC article.
Conventional Pathology Versus Gene Signatures for Assessing Luminal A and B Type Breast Cancers: Results of a Prospective Cohort Study.
Julia E C van Steenhoven, Anne Kuijer, +12 authors, Thijs van Dalen.
Genes (Basel), 2018 May 19; 9(5). PMID: 29772837    Free PMC article.
Novel evaluation scale for QOL (QOL-ACD-BP) in preoperative chemotherapy for breast cancer.
Koji Takada, Shinichiro Kashiwagi, +7 authors, Masaichi Ohira.
J Cancer Res Clin Oncol, 2018 May 21; 144(8). PMID: 29779135    Free PMC article.
Comprehensive Profiling of DNA Repair Defects in Breast Cancer Identifies a Novel Class of Endocrine Therapy Resistance Drivers.
Meenakshi Anurag, Nindo Punturi, +3 authors, Svasti Haricharan.
Clin Cancer Res, 2018 May 26; 24(19). PMID: 29793947    Free PMC article.
The Association between Molecular Subtypes of Breast Cancer with Histological Grade and Lymph Node Metastases in Indonesian Woman
Yunita Setyawati, Yeni Rahmawati, +2 authors, Dewajani Purnomosari.
Asian Pac J Cancer Prev, 2018 May 29; 19(5). PMID: 29801411    Free PMC article.
A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types.
Marie-Claire Wagle, Daniel Kirouac, +20 authors, Shih-Min A Huang.
NPJ Precis Oncol, 2018 Jun 07; 2(1). PMID: 29872725    Free PMC article.
Stem cells purified from human induced pluripotent stem cell-derived neural crest-like cells promote peripheral nerve regeneration.
Hiroo Kimura, Takehito Ouchi, +7 authors, Kazuki Sato.
Sci Rep, 2018 Jul 04; 8(1). PMID: 29968745    Free PMC article.
Triple-negative and HER2 positive ductal carcinoma in situ of the breast: characteristics, behavior, and biomarker profile.
Satoshi Takahashi, Aye Aye Thike, +2 authors, Puay Hoon Tan.
Virchows Arch, 2018 Jul 24; 473(3). PMID: 30033510
Characterization of FGD5 Expression in Primary Breast Cancers and Lymph Node Metastases.
Marit Valla, Patricia G Mjønes, +7 authors, Anna M Bofin.
J Histochem Cytochem, 2018 Jul 28; 66(11). PMID: 30052477    Free PMC article.
Intracellular hypoxia measured by 18F-fluoromisonidazole positron emission tomography has prognostic impact in patients with estrogen receptor-positive breast cancer.
Aya Asano, Shigeto Ueda, +8 authors, Toshiaki Saeki.
Breast Cancer Res, 2018 Jul 29; 20(1). PMID: 30053906    Free PMC article.
Systematic review of the impact of breast-conserving surgery on cancer outcomes of multiple ipsilateral breast cancers.
Z E Winters, J Horsnell, +13 authors, A M Brunt.
BJS Open, 2018 Aug 07; 2(4). PMID: 30079385    Free PMC article.
Review.
Practical Consequences Resulting from the Analysis of a 21-Multigene Array in the Interdisciplinary Conference of a Breast Cancer Center.
Hans-Ullrich Voelker, Lea Frey, Annette Strehl, Michael Weigel.
Int J Breast Cancer, 2018 Aug 17; 2018. PMID: 30112216    Free PMC article.
Scinderin-knockdown inhibits proliferation and promotes apoptosis in human breast carcinoma cells.
Wenjing Jian, Xiaoli Zhang, +4 authors, Renbin Liu.
Oncol Lett, 2018 Aug 22; 16(3). PMID: 30127916    Free PMC article.
OLFM4, LY6D and S100A7 as potent markers for distant metastasis in estrogen receptor-positive breast carcinoma.
Akifumi Mayama, Kiyoshi Takagi, +10 authors, Takashi Suzuki.
Cancer Sci, 2018 Aug 24; 109(10). PMID: 30137688    Free PMC article.
Ki 67 assessment in breast cancer in an Egyptian population: a comparative study between manual assessment on optical microscopy and digital quantitative assessment.
Essam Ayad, Ahmed Soliman, +3 authors, Youhong Dong.
Diagn Pathol, 2018 Aug 30; 13(1). PMID: 30153851    Free PMC article.
Significance of HER2 and Ki-67 in Preneoplastic Lesions and Carcinoma of Gallbladder.
Sutapa Halder, Sayan Kundu, Jayati Chakraborty, Sudipta Chakrabarti.
J Gastrointest Cancer, 2018 Aug 30; 50(4). PMID: 30155833
Genomic Testing in the Management of Early-Stage Breast Cancer.
Sima Ehsani, Kari Braun Wisinski.
J Clin Outcomes Manag, 2017 May 01; 24(5). PMID: 30158821    Free PMC article.
The prognostic effects of somatic mutations in ER-positive breast cancer.
Obi L Griffith, Nicholas C Spies, +30 authors, Matthew J Ellis.
Nat Commun, 2018 Sep 06; 9(1). PMID: 30181556    Free PMC article.
Could local surgery improve survival in de novo stage IV breast cancer?
Zhenchong Xiong, Guangzheng Deng, +4 authors, Xi Wang.
BMC Cancer, 2018 Sep 12; 18(1). PMID: 30200932    Free PMC article.
microRNA Regulation in Estrogen Receptor-Positive Breast Cancer and Endocrine Therapy.
Erin W Howard, Xiaohe Yang.
Biol Proced Online, 2018 Sep 15; 20. PMID: 30214383    Free PMC article.
Review.
Immunoexpression of claudins 4 and 7 among invasive breast carcinoma subtypes: A large diagnostic study using tissue microarray.
Angela Flávia Logullo, Fatima Solange Pasini, +3 authors, Maria Mitzi Brentani.
Mol Clin Oncol, 2018 Sep 15; 9(4). PMID: 30214726    Free PMC article.
Intravoxel incoherent motion magnetic resonance imaging for breast cancer: A comparison with benign lesions and evaluation of heterogeneity in different tumor regions with prognostic factors and molecular classification.
Ming Zhao, Kuang Fu, +6 authors, Jiawei Tian.
Oncol Lett, 2018 Sep 27; 16(4). PMID: 30250578    Free PMC article.
Assessing the efficacy of androgen receptor and Sox10 as independent markers of the triple-negative breast cancer subtype by transcriptome profiling.
Khalid N Al-Zahrani, David P Cook, Barbara C Vanderhyden, Luc A Sabourin.
Oncotarget, 2018 Oct 04; 9(70). PMID: 30279965    Free PMC article.
VOPP1 promotes breast tumorigenesis by interacting with the tumor suppressor WWOX.
Florian Bonin, Karim Taouis, +16 authors, Keltouma Driouch.
BMC Biol, 2018 Oct 05; 16(1). PMID: 30285739    Free PMC article.
Predicting the molecular subtype of breast cancer based on mammography and ultrasound findings.
S Rashmi, S Kamala, +3 authors, K Veeraiah Chaudhary.
Indian J Radiol Imaging, 2018 Oct 16; 28(3). PMID: 30319215    Free PMC article.
Cancer stem cell markers ALDH1 and CD44+/CD24- phenotype and their prognosis impact in invasive ductal carcinoma.
Iris Rabinovich, Ana Paula Martins Sebastião, +6 authors, Andréa Novais Moreno-Amaral.
Eur J Histochem, 2018 Oct 27; 62(3). PMID: 30362671    Free PMC article.
TIM-3 expression in breast cancer.
Samantha Burugu, Dongxia Gao, +2 authors, Torsten O Nielsen.
Oncoimmunology, 2018 Nov 01; 7(11). PMID: 30377566    Free PMC article.
Expression of estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2, and Ki-67 in ductal carcinoma in situ (DCIS) and DCIS with microinvasion.
Zhi-Bin Wan, Hong-Yi Gao, +5 authors, Yan Zhang.
Medicine (Baltimore), 2018 Nov 02; 97(44). PMID: 30383678    Free PMC article.
Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.
Yoshikazu Johmura, Ichiro Maeda, +17 authors, Makoto Nakanishi.
J Clin Invest, 2018 Nov 13; 128(12). PMID: 30418174    Free PMC article.
Distinct expression profiles and functions of Kindlins in breast cancer.
Paula Azorin, Florian Bonin, +8 authors, Keltouma Driouch.
J Exp Clin Cancer Res, 2018 Nov 28; 37(1). PMID: 30477537    Free PMC article.
Optoacoustic imaging of the breast: correlation with histopathology and histopathologic biomarkers.
Gisela L G Menezes, Ritse M Mann, +5 authors, Ruud M Pijnappel.
Eur Radiol, 2019 May 28; 29(12). PMID: 31134367    Free PMC article.
The role of Ki-67 in Asian triple negative breast cancers: a novel combinatory panel approach.
An Sen Tan, Joe Poe Sheng Yeong, +8 authors, Puay Hoon Tan.
Virchows Arch, 2019 Aug 14; 475(6). PMID: 31407032
Ki-67 (30-9) scoring and differentiation of Luminal A- and Luminal B-like breast cancer subtypes.
Giuseppe Viale, Amy E Hanlon Newell, +5 authors, Patrick Maisonneuve.
Breast Cancer Res Treat, 2019 Aug 20; 178(2). PMID: 31422497    Free PMC article.
Clinical Theragnostic Relationship between Drug-Resistance Specific miRNA Expressions, Chemotherapeutic Resistance, and Sensitivity in Breast Cancer: A Systematic Review and Meta-Analysis.
Rama Jayaraj, Sankaranarayanan Gomathi Nayagam, +12 authors, Sunil Krishnan.
Cells, 2019 Oct 17; 8(10). PMID: 31615089    Free PMC article.
Systematic Review.
External quality assessment (EQA) program for the immunohistochemical detection of ER, PR and Ki-67 in breast cancer: results of an interlaboratory reproducibility ring study in China.
Tianjie Pu, Ruohong Shui, +6 authors, China Anticancer Association Professional Committee of Tumour Pathology.
BMC Cancer, 2019 Oct 24; 19(1). PMID: 31640622    Free PMC article.
Identifying breast cancer patients who require a double-check of preoperative core needle biopsy and postoperative surgical specimens to determine the molecular subtype of their tumor.
Je Hyung Park, Hyun Yul Kim, +3 authors, Hyun-June Paik.
Ann Surg Treat Res, 2019 Nov 20; 97(5). PMID: 31742206    Free PMC article.
Dual time point 18F-fluorodeoxyglucose positron emission tomography/computed tomography fusion imaging (18F-FDG PET/CT) in primary breast cancer.
Yoji Yamagishi, Tomomi Koiwai, +8 authors, Hitoshi Tsuda.
BMC Cancer, 2019 Nov 30; 19(1). PMID: 31775675    Free PMC article.
Luminal B is the Most Common Intrinsic Molecular Subtypes of Invasive Ductal Breast Carcinoma Patients in East Kalimantan, Indonesia.
Swandari Paramita, Eko Nugroho Raharjo, +2 authors, Nur Ahlina Hanifah.
Asian Pac J Cancer Prev, 2019 Aug 28; 20(8). PMID: 31450891    Free PMC article.
The Exosome And Breast Cancer Cell Plasticity.
Xiaoyun Mao, Feng Jin.
Onco Targets Ther, 2019 Dec 11; 12. PMID: 31819481    Free PMC article.
Review.
Clinical Validation of BCT Scores With Prognostic Factors in Hormone Receptor-positive, HER2-negative Early Breast Cancer.
Jeeyeon Lee, Won Hwa Kim, +9 authors, Ho Yong Park.
In Vivo, 2019 Oct 31; 33(6). PMID: 31662548    Free PMC article.
Quantitative and Qualitative Evaluation of Breast Cancer Prognosis: A Sonographic Elastography Study.
Yue You, Yu Song, +2 authors, Huaying Bo.
Med Sci Monit, 2019 Dec 06; 25. PMID: 31802780    Free PMC article.
Endocrine-responsive lobular carcinoma of the breast: features associated with risk of late distant recurrence.
Fabio Conforti, Laura Pala, +12 authors, Aron Goldhirsch.
Breast Cancer Res, 2020 Jan 01; 21(1). PMID: 31888717    Free PMC article.
Neoadjuvant Metformin Added to Systemic Therapy Decreases the Proliferative Capacity of Residual Breast Cancer.
Eugeni Lopez-Bonet, Maria Buxó, +24 authors, Javier A Menendez.
J Clin Med, 2019 Dec 15; 8(12). PMID: 31835708    Free PMC article.
Correlation between procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 and breast cancer.
Hao-Lin Hu, Chen-Fei Wang, +5 authors, Ya-Nan Zhang.
Int J Clin Exp Pathol, 2020 Jan 15; 12(3). PMID: 31933913    Free PMC article.
Prognostic impact of high p16/cyclin D1 index in breast cancer.
Gi Jeong Kim, Dong-Hoon Kim, Kyueng-Whan Min, Se Hoon Kim.
Int J Clin Exp Pathol, 2020 Jan 15; 12(6). PMID: 31934045    Free PMC article.
The prognostic and predictive potential of Ki-67 in triple-negative breast cancer.
Xiuzhi Zhu, Li Chen, +8 authors, Zhonghua Wang.
Sci Rep, 2020 Jan 16; 10(1). PMID: 31937819    Free PMC article.
Ki-67 Expression is a Significant Prognostic Factor Only When Progesterone Receptor Expression is Low in Estrogen Receptor-Positive and HER2-Negative Early Breast Cancer.
Young-Joon Kang, Han-Byoel Lee, +7 authors, Wonshik Han.
J Oncol, 2020 Jan 25; 2019. PMID: 31975992    Free PMC article.
Response to immunohistochemical markers' conversion after neoadjuvant chemotherapy in breast cancer patients: association between imaging and histopathologic analysis.
Y Zhao, X Wang, +2 authors, D Zhang.
Clin Transl Oncol, 2019 Apr 22; 22(1). PMID: 31006089
Invasive ductal breast cancer: preoperative predict Ki-67 index based on radiomics of ADC maps.
Yu Zhang, Yifeng Zhu, +5 authors, Shaowu Wang.
Radiol Med, 2019 Nov 07; 125(2). PMID: 31696388
Assessment of Ki67 expression for breast cancer subtype classification and prognosis in the Nurses' Health Study.
Megan A Healey, Kelly A Hirko, +6 authors, Aditi Hazra.
Breast Cancer Res Treat, 2017 Aug 10; 166(2). PMID: 28791482    Free PMC article.
Analysis of the molecular subtypes of preoperative core needle biopsy and surgical specimens in invasive breast cancer.
Ye Sul Jeong, Jun Kang, +3 authors, Ahwon Lee.
J Pathol Transl Med, 2019 Nov 14; 54(1). PMID: 31718121    Free PMC article.
Mismatch repair protein loss in breast cancer: clinicopathological associations in a large British Columbia cohort.
Angela S Cheng, Samuel C Y Leung, +4 authors, Torsten O Nielsen.
Breast Cancer Res Treat, 2019 Sep 16; 179(1). PMID: 31522348    Free PMC article.
Paclitaxel's Mechanistic and Clinical Effects on Breast Cancer.
Tala M Abu Samaan, Marek Samec, +2 authors, Dietrich Büsselberg.
Biomolecules, 2019 Dec 01; 9(12). PMID: 31783552    Free PMC article.
Review.
Photoacoustic imaging of breast cancer: a mini review of system design and image features.
Nikhila Nyayapathi, Jun Xia.
J Biomed Opt, 2019 Nov 05; 24(12). PMID: 31677256    Free PMC article.
Review.
MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes.
Elise Klæstad, Signe Opdahl, +4 authors, Marit Valla.
Breast Cancer Res Treat, 2020 Jan 18; 180(1). PMID: 31950385    Free PMC article.
PCA-PAM50 improves consistency between breast cancer intrinsic and clinical subtyping reclassifying a subset of luminal A tumors as luminal B.
Praveen-Kumar Raj-Kumar, Jianfang Liu, +4 authors, Hai Hu.
Sci Rep, 2019 May 30; 9(1). PMID: 31138829    Free PMC article.
Clinical outcomes of an intraoperative surgical margin assessment using the fresh frozen section method in patients with invasive breast cancer undergoing breast-conserving surgery - a single center analysis.
Tomasz Nowikiewicz, Ewa Śrutek, +3 authors, Wojciech Zegarski.
Sci Rep, 2019 Sep 19; 9(1). PMID: 31530867    Free PMC article.
Prognostic Value of the Progesterone Receptor by Subtype in Patients with Estrogen Receptor-Positive, HER-2 Negative Breast Cancer.
Kathleen Van Asten, Laurence Slembrouck, +16 authors, Patrick Neven.
Oncologist, 2018 Sep 02; 24(2). PMID: 30171067    Free PMC article.
PAM50 Molecular Intrinsic Subtypes in the Nurses' Health Study Cohorts.
Kevin H Kensler, Venkat N Sankar, +13 authors, Yujing J Heng.
Cancer Epidemiol Biomarkers Prev, 2018 Dec 29; 28(4). PMID: 30591591    Free PMC article.
Association Between Postpartum Breast Cancer Diagnosis and Metastasis and the Clinical Features Underlying Risk.
Erica T Goddard, Solange Bassale, +8 authors, Virginia F Borges.
JAMA Netw Open, 2019 Jan 16; 2(1). PMID: 30646210    Free PMC article.
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Cell Rep, 2019 Jan 17; 26(3). PMID: 30650356    Free PMC article.
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PLoS One, 2019 Feb 21; 14(2). PMID: 30785924    Free PMC article.
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Br J Cancer, 2019 Mar 23; 120(9). PMID: 30899086    Free PMC article.
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Front Genet, 2020 Mar 17; 11. PMID: 32174978    Free PMC article.
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Oncol Lett, 2020 Mar 21; 19(3). PMID: 32194687    Free PMC article.
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J Transl Med, 2020 Apr 07; 18(1). PMID: 32248830    Free PMC article.
Gene expression profiling revealed MCM3 to be a better marker than Ki67 in prognosis of invasive ductal breast carcinoma patients.
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Clin Exp Med, 2020 Jan 26; 20(2). PMID: 31980982
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J Breast Cancer, 2020 May 13; 23(2). PMID: 32395377    Free PMC article.
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J Natl Cancer Inst, 2019 Oct 08; 112(5). PMID: 31589320    Free PMC article.
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Cell Rep, 2020 Jun 11; 31(10). PMID: 32521270    Free PMC article.
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Ann Surg Oncol, 2020 Mar 04; 27(8). PMID: 32124121    Free PMC article.
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Front Oncol, 2020 Jul 23; 10. PMID: 32695676    Free PMC article.
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Front Oncol, 2020 Jul 23; 10. PMID: 32695682    Free PMC article.
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Do YOU know the Ki-67 index of your breast cancer patients? Knowledge of your institution's Ki-67 index distribution and its robustness is essential for decision-making in early breast cancer.
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Breast, 2020 Apr 18; 51. PMID: 32302928    Free PMC article.
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Breast Cancer Res Treat, 2021 Jan 04; 185(3). PMID: 33389409    Free PMC article.
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A Novel Neoplastic Fusion Transcript, RAD51AP1-DYRK4, Confers Sensitivity to the MEK Inhibitor Trametinib in Aggressive Breast Cancers.
Chia-Chia Liu, Jamunarani Veeraraghavan, +6 authors, Xiao-Song Wang.
Clin Cancer Res, 2020 Nov 12; 27(3). PMID: 33172895    Free PMC article.
Genomic Assays in Node Positive Breast Cancer Patients: A Review.
Maroun Bou Zerdan, Maryam Ibrahim, +2 authors, Hazem I Assi.
Front Oncol, 2021 Mar 06; 10. PMID: 33665165    Free PMC article.
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Advanced Approaches to Breast Cancer Classification and Diagnosis.
M Zubair, S Wang, N Ali.
Front Pharmacol, 2021 Mar 16; 11. PMID: 33716731    Free PMC article.
Review.
Prognostic impact of the glypican family of heparan sulfate proteoglycans on the survival of breast cancer patients.
Paulina Karin Grillo, Balázs Győrffy, Martin Götte.
J Cancer Res Clin Oncol, 2021 Mar 21; 147(7). PMID: 33742285    Free PMC article.
Tucatinib Inhibits Renal Transporters OCT2 and MATE Without Impacting Renal Function in Healthy Subjects.
Ariel R Topletz-Erickson, Anthony J Lee, +8 authors, Christopher J Endres.
J Clin Pharmacol, 2020 Sep 30; 61(4). PMID: 32989831    Free PMC article.
High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer.
Gerardo Gatti, Courtney Betts, +11 authors, Mariana Maccioni.
Breast Cancer Res, 2021 Mar 27; 23(1). PMID: 33766090    Free PMC article.
An analysis of Ki-67 expression in stage 1 invasive ductal breast carcinoma using apparent diffusion coefficient histograms.
Maolin Xu, Qi Tang, +2 authors, Fang Li.
Quant Imaging Med Surg, 2021 Apr 06; 11(4). PMID: 33816188    Free PMC article.
Prognostic significance of TRIM28 expression in patients with breast carcinoma.
Wen Zhang, Zhengquan Cai, +4 authors, Hua Wang.
Open Med (Wars), 2021 Apr 06; 16(1). PMID: 33817325    Free PMC article.
Expression of CCL2/CCR2 signaling proteins in breast carcinoma cells is associated with invasive progression.
Wei Bin Fang, Diana Sofia Acevedo, +12 authors, Nikki Cheng.
Sci Rep, 2021 Apr 24; 11(1). PMID: 33888841    Free PMC article.
Metabolism and immunity in breast cancer.
Deyu Zhang, Xiaojie Xu, Qinong Ye.
Front Med, 2020 Oct 20; 15(2). PMID: 33074528
Review.
Nomograms for Predicting Axillary Lymph Node Status Reconciled With Preoperative Breast Ultrasound Images.
Dongmei Liu, Yujia Lan, +7 authors, Xia Li.
Front Oncol, 2021 Apr 27; 11. PMID: 33898303    Free PMC article.
DTX3 copy number increase in breast cancer: a study of associations to molecular subtype, proliferation and prognosis.
Marit Valla, Signe Opdahl, Borgny Ytterhus, Anna Mary Bofin.
Breast Cancer Res Treat, 2021 Feb 23; 187(1). PMID: 33616774    Free PMC article.
Current Biomarkers for Precision Medicine in Breast Cancer.
Soo Kyung Ahn, So-Youn Jung.
Adv Exp Med Biol, 2021 May 14; 1187. PMID: 33983588
Prognostic relevance of Ki67 expression in primary male breast cancer: determination of cut-off points by different evaluation methods and statistical examinations.
Melanie Erices-Leclercq, Sabine Lubig, +4 authors, Lars Schröder.
J Cancer Res Clin Oncol, 2021 May 16;. PMID: 33991247
Differentiation and Regulation of TH Cells: A Balancing Act for Cancer Immunotherapy.
Amrita Basu, Ganesan Ramamoorthi, +7 authors, Krithika Kodumudi.
Front Immunol, 2021 May 21; 12. PMID: 34012451    Free PMC article.
Review.
Vitamin D receptor (VDR) expression in different molecular subtypes of canine mammary carcinoma.
R Sánchez-Céspedes, M D Fernández-Martínez, +3 authors, Y Millán.
BMC Vet Res, 2021 May 27; 17(1). PMID: 34034728    Free PMC article.
Expression of thrombospondin-1 in conjunctival squamous cell carcinoma is correlated to the Ki67 index and associated with progression-free survival.
Mizuki Tagami, Anna Kakehashi, +5 authors, Shigeru Honda.
Graefes Arch Clin Exp Ophthalmol, 2021 May 30; 259(10). PMID: 34050808
Peritumoral edema in breast cancer at preoperative MRI: an interpretative study with histopathological review toward understanding tumor microenvironment.
Nora Jee-Young Park, Ji Yun Jeong, +9 authors, Won Hwa Kim.
Sci Rep, 2021 Jun 23; 11(1). PMID: 34155253    Free PMC article.
Update Breast Cancer 2021 Part 3 - Current Developments in the Treatment of Early Breast Cancer: Review and Assessment of Specialised Treatment Scenarios by an International Expert Panel.
Tanja N Fehm, Elmar Stickeler, +16 authors, Andreas D Hartkopf.
Geburtshilfe Frauenheilkd, 2021 Jun 26; 81(6). PMID: 34168379    Free PMC article.
Osmotic pressure modulates single cell cycle dynamics inducing reversible growth arrest and reactivation of human metastatic cells.
Hubert M Taïeb, Daniela S Garske, +4 authors, Amaia Cipitria.
Sci Rep, 2021 Jul 01; 11(1). PMID: 34188099    Free PMC article.
Breast cancer: Muscarinic receptors as new targets for tumor therapy.
Alejandro Español, Agustina Salem, Yamila Sanchez, María Elena Sales.
World J Clin Oncol, 2021 Jul 01; 12(6). PMID: 34189066    Free PMC article.
Review.
Chronological Trends of Breast Ductal Carcinoma In Situ: Clinical, Radiologic, and Pathologic Perspectives.
Si Eun Lee, Ha Yan Kim, +6 authors, Hee Jung Moon.
Ann Surg Oncol, 2021 Jul 02;. PMID: 34196861
The Multifaceted Functions of Autophagy in Breast Cancer Development and Treatment.
Nicolas J Niklaus, Igor Tokarchuk, +3 authors, Mario P Tschan.
Cells, 2021 Jul 03; 10(6). PMID: 34207792    Free PMC article.
Review.
Predictive Role of Leptin Receptor (Ob-R) Overexpression in Patients with Early Breast Cancer Receiving Neoadjuvant Systemic Treatment.
Laura García-Estévez, Isabel Calvo, +5 authors, Gema Moreno-Bueno.
Cancers (Basel), 2021 Jul 03; 13(13). PMID: 34210055    Free PMC article.
Correlation between ER, PR, HER-2, and Ki-67 with the risk of bone metastases detected by bone scintigraphy in breast cancer patients: A cross sectional study.
Hanif Afkari, Firdian Makrufardi, +2 authors, Achmad Hussein Sundawa Kartamihardja.
Ann Med Surg (Lond), 2021 Jul 15; 67. PMID: 34257962    Free PMC article.
Invasive lobular carcinoma: clinicopathological features and subtypes.
Sabine Danzinger, Nora Hielscher, +5 authors, Christian F Singer.
J Int Med Res, 2021 Jul 01; 49(6). PMID: 34187216    Free PMC article.
Accurate prediction of breast cancer survival through coherent voting networks with gene expression profiling.
Marco Pellegrini.
Sci Rep, 2021 Jul 21; 11(1). PMID: 34282236    Free PMC article.
Valproic Acid and Breast Cancer: State of the Art in 2021.
Anna Wawruszak, Marta Halasa, +2 authors, Andrzej Stepulak.
Cancers (Basel), 2021 Jul 25; 13(14). PMID: 34298623    Free PMC article.
Review.
Precision treatment exploration of breast cancer based on heterogeneity analysis of lncRNAs at the single-cell level.
Yan Zhang, Denan Zhang, +5 authors, Xiujie Chen.
BMC Cancer, 2021 Aug 15; 21(1). PMID: 34388989    Free PMC article.
Expression profiles and functional prediction of long non-coding RNAs LINC01133, ZEB1-AS1 and ABHD11-AS1 in the luminal subtype of breast cancer.
Sepideh Mehrpour Layeghi, Maedeh Arabpour, +4 authors, Rezvan Esmaeili.
J Transl Med, 2021 Aug 28; 19(1). PMID: 34446052    Free PMC article.
Sugar-Sweetened Beverages, Artificially Sweetened Beverages, and Breast Cancer Risk: Results From 2 Prospective US Cohorts.
Andrea Romanos-Nanclares, Laura C Collins, +4 authors, A Heather Eliassen.
J Nutr, 2021 Jun 12; 151(9). PMID: 34114021    Free PMC article.
Breast Cancer-Epidemiology, Risk Factors, Classification, Prognostic Markers, and Current Treatment Strategies-An Updated Review.
Sergiusz Łukasiewicz, Marcin Czeczelewski, +3 authors, Andrzej Stanisławek.
Cancers (Basel), 2021 Sep 11; 13(17). PMID: 34503097    Free PMC article.
Review.
Ki-67 as a Prognostic Biomarker in Invasive Breast Cancer.
Matthew G Davey, Sean O Hynes, +2 authors, Aoife J Lowery.
Cancers (Basel), 2021 Sep 11; 13(17). PMID: 34503265    Free PMC article.
Review.
Molecular alterations differentiate microinvasive carcinoma from ductal carcinoma in situ and invasive breast carcinoma: retrospective analysis of a large single-center series.
Yan Zhang, Ying Wu, +3 authors, Hong-Yi Gao.
Int J Clin Exp Pathol, 2021 Sep 17; 14(8). PMID: 34527132    Free PMC article.
Vorinostat (SAHA) and Breast Cancer: An Overview.
Anna Wawruszak, Lidia Borkiewicz, +3 authors, Marta Halasa.
Cancers (Basel), 2021 Sep 29; 13(18). PMID: 34572928    Free PMC article.
Review.
Reproducibility of mRNA-Based Testing of ESR1, PGR, ERBB2, and MKI67 Expression in Invasive Breast Cancer-A Europe-Wide External Quality Assessment.
Ramona Erber, Arndt Hartmann, +22 authors, Fulvia Ferrazzi.
Cancers (Basel), 2021 Sep 29; 13(18). PMID: 34572945    Free PMC article.
Improving Prognosis of Surrogate Assay for Breast Cancer Patients by Absolute Quantitation of Ki67 Protein Levels Using Quantitative Dot Blot (QDB) Method.
Junmei Hao, Yan Lyu, +10 authors, Jiandi Zhang.
Front Oncol, 2021 Oct 05; 11. PMID: 34604077    Free PMC article.
Healthful and Unhealthful Plant-Based Diets and Risk of Breast Cancer in U.S. Women: Results from the Nurses' Health Studies.
Andrea Romanos-Nanclares, Walter C Willett, +4 authors, A Heather Eliassen.
Cancer Epidemiol Biomarkers Prev, 2021 Jul 23; 30(10). PMID: 34289970    Free PMC article.