Journal Article
. 2009 Jun;20(8).
doi: 10.1093/annonc/mdp322.

Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009

A Goldhirsch 1 J N Ingle  R D Gelber  A S Coates  B Thürlimann  H-J Senn  Panel members  
Affiliations
  • PMID: 19535820
  •     64 References
  •     367 citations

Abstract

The 11(th) St Gallen (Switzerland) expert consensus meeting on the primary treatment of early breast cancer in March 2009 maintained an emphasis on targeting adjuvant systemic therapies according to subgroups defined by predictive markers. Any positive level of estrogen receptor (ER) expression is considered sufficient to justify the use of endocrine adjuvant therapy in almost all patients. Overexpression or amplification of HER2 by standard criteria is an indication for anti-HER2 therapy for all but the very lowest risk invasive tumours. The corollary is that ER and HER2 must be reliably and accurately measured. Indications for cytotoxic adjuvant therapy were refined, acknowledging the role of risk factors with the caveat that risk per se is not a target. Proliferation markers, including those identified in multigene array analyses, were recognised as important in this regard. The threshold for indication of each systemic treatment modality thus depends on different criteria which have been separately listed to clarify the therapeutic decision-making algorithm.

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Eva J Kantelhardt, Martina Vetter, +12 authors, Nadia Harbeck.
BMC Cancer, 2011 Apr 19; 11. PMID: 21496284    Free PMC article.
Use of tamoxifen and aromatase inhibitors in a large population-based cohort of women with breast cancer.
L Huiart, S Dell'Aniello, S Suissa.
Br J Cancer, 2011 Apr 28; 104(10). PMID: 21522148    Free PMC article.
Factors influencing treatment recommendations in node-negative breast cancer.
Elisabeth Edstrom Elder, Sally Baron Hay, Katrina Moore.
J Oncol Pract, 2011 May 03; 7(1). PMID: 21532807    Free PMC article.
Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications.
Taru A Muranen, Dario Greco, +7 authors, Heli Nevanlinna.
Breast Cancer Res, 2011 May 06; 13(5). PMID: 21542898    Free PMC article.
Tamoxifen in early-stage estrogen receptor-positive breast cancer: overview of clinical use and molecular biomarkers for patient selection.
Carmen Criscitiello, Debora Fumagalli, Kamal S Saini, Sherene Loi.
Onco Targets Ther, 2011 May 10; 4. PMID: 21552410    Free PMC article.
Prognostic utility of HOXB13:IL17BR and molecular grade index in early-stage breast cancer patients from the Stockholm trial.
P-L Jerevall, X-J Ma, +9 authors, O Stål.
Br J Cancer, 2011 May 12; 104(11). PMID: 21559019    Free PMC article.
All nodes lead to chemo...
Lidia Schapira, Michaela J Higgins.
Oncologist, 2011 May 19; 16(5). PMID: 21586662    Free PMC article.
St. Gallen 2011: Summary of the Consensus Discussion.
Michael Gnant, Nadia Harbeck, Christoph Thomssen.
Breast Care (Basel), 2011 Jun 03; 6(2). PMID: 21633630    Free PMC article.
Interpreting Breast International Group (BIG) 1-98: a randomized, double-blind, phase III trial comparing letrozole and tamoxifen as adjuvant endocrine therapy for postmenopausal women with hormone receptor-positive, early breast cancer.
Meredith M Regan, Karen N Price, +3 authors, International Breast Cancer Study Group and BIG 1-98 Collaborative Group.
Breast Cancer Res, 2011 Jun 04; 13(3). PMID: 21635709    Free PMC article.
Review.
Different annual recurrence pattern between lumpectomy and mastectomy: implication for breast cancer surveillance after breast-conserving surgery.
Ke-Da Yu, Shuang Li, Zhi-Ming Shao.
Oncologist, 2011 Jun 18; 16(8). PMID: 21680575    Free PMC article.
Strategies for subtypes--dealing with the diversity of breast cancer: highlights of the St. Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011.
A Goldhirsch, W C Wood, +4 authors, Panel members.
Ann Oncol, 2011 Jun 29; 22(8). PMID: 21709140    Free PMC article.
Highly Cited.
Clinical epidemiology and pharmacology of CYP2D6 inhibition related to breast cancer outcomes.
Deirdre P Cronin-Fenton, Timothy L Lash.
Expert Rev Clin Pharmacol, 2011 Jun 29; 4(3). PMID: 21709817    Free PMC article.
Review.
Prediction of outcome of early ER+ breast cancer is improved using a biomarker panel, which includes Ki-67 and p53.
E K A Millar, P H Graham, +10 authors, R L Sutherland.
Br J Cancer, 2011 Jun 30; 105(2). PMID: 21712826    Free PMC article.
Effect of Supplementation of Tanshinone IIA and Sodium Tanshinone IIA Sulfonate on the Anticancer Effect of Epirubicin: An In Vitro Study.
Szu-Erh Chan, Hung-Wen Lai, +4 authors, Dar-Ren Chen.
Evid Based Complement Alternat Med, 2011 Jul 01; 2011. PMID: 21716682    Free PMC article.
Immune effects of trastuzumab.
Marianna Nuti, Filippo Bellati, +8 authors, Aurelia Rughetti.
J Cancer, 2011 Jul 01; 2. PMID: 21716848    Free PMC article.
A simple method for assigning genomic grade to individual breast tumours.
Kristian Wennmalm, Jonas Bergh.
BMC Cancer, 2011 Jul 23; 11. PMID: 21777443    Free PMC article.
Adjuvant Systemic Therapy of Breast Cancer.
Florian Schuetz.
Breast Care (Basel), 2011 Jul 23; 6(3). PMID: 21779222    Free PMC article.
Prognostic and Predictive Markers for Treatment Decisions in Early Breast Cancer.
Elmar Stickeler.
Breast Care (Basel), 2011 Jul 23; 6(3). PMID: 21779224    Free PMC article.
Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction.
Pierre-Emmanuel Colombo, Fernanda Milanezi, Britta Weigelt, Jorge S Reis-Filho.
Breast Cancer Res, 2011 Jul 27; 13(3). PMID: 21787441    Free PMC article.
Review.
Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials.
Early Breast Cancer Trialists' Collaborative Group (EBCTCG), C Davies, +11 authors, R Peto.
Lancet, 2011 Aug 02; 378(9793). PMID: 21802721    Free PMC article.
Highly Cited.
Molecular serum portraits in patients with primary breast cancer predict the development of distant metastases.
Anders Carlsson, Christer Wingren, +10 authors, Carl A K Borrebaeck.
Proc Natl Acad Sci U S A, 2011 Aug 17; 108(34). PMID: 21844363    Free PMC article.
The advantage of letrozole over tamoxifen in the BIG 1-98 trial is consistent in younger postmenopausal women and in those with chemotherapy-induced menopause.
Jacquie Chirgwin, Zhuoxin Sun, +8 authors, BIG 1-98 Collaborative and International Breast Cancer Study Groups.
Breast Cancer Res Treat, 2011 Sep 06; 131(1). PMID: 21892704    Free PMC article.
Breast medical oncologists' use of standard prognostic factors to predict a 21-gene recurrence score.
Arif H Kamal, Charles L Loprinzi, +7 authors, Matthew P Goetz.
Oncologist, 2011 Sep 22; 16(10). PMID: 21934103    Free PMC article.
Pharmacoeconomic considerations in the treatment of breast cancer.
Athanasios Pallis, Vasiliki Tsiantou, Efi Simou, Nikos Maniadakis.
Clinicoecon Outcomes Res, 2010 Jan 01; 2. PMID: 21935314    Free PMC article.
Prognostic and predictive role of ESR1 status for postmenopausal patients with endocrine-responsive early breast cancer in the Danish cohort of the BIG 1-98 trial.
B Ejlertsen, J Aldridge, +10 authors, Danish Breast Cancer Cooperative Group the BIG 1-98 Collaborative Group and the International Breast Cancer Study Group.
Ann Oncol, 2011 Oct 12; 23(5). PMID: 21986093    Free PMC article.
Prognostic utility of the breast cancer index and comparison to Adjuvant! Online in a clinical case series of early breast cancer.
Rachel C Jankowitz, Kristine Cooper, +5 authors, Adam Brufsky.
Breast Cancer Res, 2011 Oct 18; 13(5). PMID: 21999244    Free PMC article.
Changes in the ER, PgR, HER2, p53 and Ki-67 biological markers between primary and recurrent breast cancer: discordance rates and prognosis.
Reiki Nishimura, Tomofumi Osako, +3 authors, Nobuyuki Arima.
World J Surg Oncol, 2011 Oct 19; 9. PMID: 22004841    Free PMC article.
High rate of extra-haematological toxicity compromises dose-dense sequential adjuvant chemotherapy for breast cancer.
E Brain, C Levy, +12 authors, P Fumoleau.
Br J Cancer, 2011 Oct 20; 105(10). PMID: 22009030    Free PMC article.
Degree of variability in performance on breast cancer quality indicators: findings from the Florida initiative for quality cancer care.
Jhanelle E Gray, Christine Laronga, +16 authors, Paul B Jacobsen.
J Oncol Pract, 2011 Nov 02; 7(4). PMID: 22043190    Free PMC article.
Ki-67: level of evidence and methodological considerations for its role in the clinical management of breast cancer: analytical and critical review.
Elisabeth Luporsi, Fabrice André, +22 authors, Jean-Pierre Bellocq.
Breast Cancer Res Treat, 2011 Nov 04; 132(3). PMID: 22048814    Free PMC article.
Highly Cited. Review.
A case of HER-2-positive recurrent breast cancer showing a clinically complete response to trastuzumab-containing chemotherapy after primary treatment of triple-negative breast cancer.
Hideo Shigematsu, Takayuki Kadoya, +9 authors, Morihito Okada.
World J Surg Oncol, 2011 Nov 09; 9. PMID: 22059982    Free PMC article.
Exemestane in the adjuvant treatment of breast cancer in postmenopausal women.
Muaiad Kittaneh, Stefan Glück.
Breast Cancer (Auckl), 2011 Nov 16; 5. PMID: 22084574    Free PMC article.
Zoledronic acid in breast cancer: latest findings and interpretations.
Michael Gnant.
Ther Adv Med Oncol, 2011 Nov 16; 3(6). PMID: 22084643    Free PMC article.
Paclitaxel-induced peripheral neuropathy in patients receiving adjuvant chemotherapy for breast cancer.
Yuko Tanabe, Kenji Hashimoto, +9 authors, Yasuhiro Fujiwara.
Int J Clin Oncol, 2011 Nov 23; 18(1). PMID: 22105895
Glycoprotein profiles of human breast cells demonstrate a clear clustering of normal/benign versus malignant cell lines and basal versus luminal cell lines.
Ten-Yang Yen, Bruce A Macher, +2 authors, Leslie C Timpe.
J Proteome Res, 2011 Nov 24; 11(2). PMID: 22106898    Free PMC article.
Zoledronic acid in the treatment of early-stage breast cancer: is there a final verdict?
Michael Gnant.
Curr Oncol Rep, 2011 Nov 25; 14(1). PMID: 22113793
Review.
The breast cancer genome--a key for better oncology.
Hans Kristian Moen Vollan, Carlos Caldas.
BMC Cancer, 2011 Dec 02; 11. PMID: 22128823    Free PMC article.
Review.
Factors associated with concordant estrogen receptor expression at diagnosis and centralized re-assay in a Danish population-based breast cancer study.
Deirdre P Cronin-Fenton, Ylva Hellberg, +7 authors, Stephen Hamilton-Dutoit.
Acta Oncol, 2011 Dec 02; 51(2). PMID: 22129357    Free PMC article.
AGO Recommendations for Diagnosis and Treatment of Patients with Primary and Metastatic Breast Cancer. Update 2011.
Christoph Thomssen, Anton Scharl, Nadia Harbeck.
Breast Care (Basel), 2011 Dec 14; 6(4). PMID: 22164127    Free PMC article.
Apoptosis - associated genes and their role in predicting responses to neoadjuvant breast cancer treatment.
Daniel Tvrdík, Helena Skálová, +5 authors, Luboš Petruželka.
Med Sci Monit, 2011 Dec 31; 18(1). PMID: 22207111    Free PMC article.
Expression of the androgen receptor and its correlation with molecular subtypes in 980 chinese breast cancer patients.
Ji-Ping Qi, You-Lin Yang, +11 authors, Ping Tang.
Breast Cancer (Auckl), 2012 Jan 20; 6. PMID: 22259247    Free PMC article.
Role of HER2-Targeted Agents in Adjuvant Treatment for Breast Cancer.
Toru Mukohara.
Chemother Res Pract, 2012 Feb 02; 2011. PMID: 22295205    Free PMC article.
Phase II trial with letrozole to maximum response as primary systemic therapy in postmenopausal patients with ER/PgR[+] operable breast cancer.
Antonio Llombart-Cussac, Ángel Guerrero, +6 authors, Vicente Guillem Porta.
Clin Transl Oncol, 2012 Feb 04; 14(2). PMID: 22301401
Is there any role for new prognostic markers in breast cancer?
Agustí Barnadas.
Clin Transl Oncol, 2012 Mar 01; 14(3). PMID: 22374417
Review.
The dyslexia candidate gene DYX1C1 is a potential marker of poor survival in breast cancer.
Gustaf Rosin, Ulf Hannelius, +4 authors, Juha Kere.
BMC Cancer, 2012 Mar 02; 12. PMID: 22375924    Free PMC article.
Correlations between diffusion-weighted imaging and breast cancer biomarkers.
Laura Martincich, Veronica Deantoni, +9 authors, Filippo Montemurro.
Eur Radiol, 2012 Mar 14; 22(7). PMID: 22411304
Capecitabine monotherapy: review of studies in first-line HER-2-negative metastatic breast cancer.
Joyce A O'Shaughnessy, Manfred Kaufmann, +4 authors, Nadia Harbeck.
Oncologist, 2012 Mar 16; 17(4). PMID: 22418569    Free PMC article.
Review.
Neoadjuvant Therapy - What Have We Achieved in the Last 20 Years?
Jens Huober, Gunter von Minckwitz.
Breast Care (Basel), 2012 Mar 16; 6(6). PMID: 22419894    Free PMC article.
Trends and Novel Approaches in Neoadjuvant Treatment of Breast Cancer.
Guenther G Steger, Rupert Bartsch.
Breast Care (Basel), 2012 Mar 16; 6(6). PMID: 22419895    Free PMC article.
Patients with positive axillary lymph nodes: how to use genomic assays.
Ruta Rao.
Curr Treat Options Oncol, 2012 Mar 20; 13(2). PMID: 22426945
Prognostic value of Bcl-2 in two independent populations of estrogen receptor positive breast cancer patients treated with adjuvant endocrine therapy.
Mathilde S Larsen, Karsten Bjerre, +5 authors, Birgitte B Rasmussen.
Acta Oncol, 2012 Apr 03; 51(6). PMID: 22462654    Free PMC article.
A comparison of survival outcomes and side effects of toremifene or tamoxifen therapy in premenopausal estrogen and progesterone receptor positive breast cancer patients: a retrospective cohort study.
Ran Gu, Weijuan Jia, +13 authors, Fengxi Su.
BMC Cancer, 2012 May 03; 12. PMID: 22548922    Free PMC article.
Managing arthralgia in a postmenopausal woman taking an aromatase inhibitor for hormonesensitive early breast cancer: a case study.
Jane Bryce, Martina Bauer, Peyman Hadji.
Cancer Manag Res, 2012 May 10; 4. PMID: 22570564    Free PMC article.
[Assessment of proliferation: core biopsy or resection specimen? Discrepancies in breast cancer with low and high proliferation].
E C Obermann, S Eppenberger-Castori, C Tapia.
Pathologe, 2012 May 12; 33(3). PMID: 22576598
Review.
Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study.
Rebecca Ritte, Annekatrin Lukanova, +44 authors, Rudolf Kaaks.
Breast Cancer Res, 2012 May 16; 14(3). PMID: 22583394    Free PMC article.
Should Postmastectomy Radiotherapy to the Chest Wall and Regional Lymph Nodes Be Standard for Patients with 1-3 Positive Lymph Nodes?
Birgitte V Offersen, Hans-Jürgen Brodersen, +2 authors, Marie Overgaard.
Breast Care (Basel), 2012 May 24; 6(5). PMID: 22619643    Free PMC article.
Ductal carcinoma in situ: what can we learn from clinical trials?
Lucio Fortunato, Igor Poccia, Ugo de Paula, Elena Santini.
Int J Surg Oncol, 2012 Jun 01; 2012. PMID: 22649720    Free PMC article.
How reliable is Ki-67 immunohistochemistry in grade 2 breast carcinomas? A QA study of the Swiss Working Group of Breast- and Gynecopathologists.
Zsuzsanna Varga, Joachim Diebold, +16 authors, Hans-Anton Lehr.
PLoS One, 2012 Jun 05; 7(5). PMID: 22662150    Free PMC article.
Fertility preservation in women undergoing treatment for breast cancer in the UK: a questionnaire study.
Judy W King, Melanie C Davies, +2 authors, Alison L Jones.
Oncologist, 2012 Jun 19; 17(7). PMID: 22707514    Free PMC article.
SULT1A1 rs9282861 polymorphism-a potential modifier of efficacy of the systemic adjuvant therapy in breast cancer?
Maria Tengström, Arto Mannermaa, +2 authors, Vesa Kataja.
BMC Cancer, 2012 Jun 20; 12. PMID: 22708928    Free PMC article.
A risk score based on histopathological features predicts higher risk of distant recurrence in premenopausal patients with lymph node-negative endocrine-responsive breast cancer.
Silvia Dellapasqua, Vincenzo Bagnardi, +9 authors, Marco Colleoni.
Breast, 2012 Jul 04; 21(5). PMID: 22749924    Free PMC article.
Increased number of regulatory T cells (T-regs) in the peripheral blood of patients with Her-2/neu-positive early breast cancer.
Thomas Decker, Gerhard Fischer, +8 authors, Katharina Götze.
J Cancer Res Clin Oncol, 2012 Jul 05; 138(11). PMID: 22760213
Patterns and risk factors for locoregional failures after mastectomy for breast cancer: an International Breast Cancer Study Group report.
P Karlsson, B F Cole, +12 authors, International Breast Cancer Study Group.
Ann Oncol, 2012 Jul 11; 23(11). PMID: 22776708    Free PMC article.
Development of novel breast cancer recurrence prediction model using support vector machine.
Woojae Kim, Ku Sang Kim, +5 authors, Rae Woong Park.
J Breast Cancer, 2012 Jul 19; 15(2). PMID: 22807942    Free PMC article.
ER and PR signaling nodes during mammary gland development.
Tamara Tanos, Lucia Rojo, Pablo Echeverria, Cathrin Brisken.
Breast Cancer Res, 2012 Jul 20; 14(4). PMID: 22809143    Free PMC article.
Review.
High-risk estrogen-receptor-positive breast cancer: identification and implications for therapy.
Rosemary L Balleine, Nicholas R Wilcken.
Mol Diagn Ther, 2012 Jul 21; 16(4). PMID: 22812573
Review.
Are there biologic differences between male and female breast cancer explaining inferior outcome of men despite equal stage and treatment?!
A-C Müller, C Gani, +4 authors, M Weinmann.
Strahlenther Onkol, 2012 Aug 01; 188(9). PMID: 22847517
The prognostic importance of cathepsin D and E-cadherin in early breast cancer: A single-institution experience.
Galia Jacobson-Raber, Irena Lazarev, +5 authors, Samuel Ariad.
Oncol Lett, 2012 Aug 01; 2(6). PMID: 22848286    Free PMC article.
A retrospective study on TS mRNA expression and prediction of the effects of adjuvant oral 5-fluorouracil in breast cancer.
Fuminori Aki, Yoshimi Bando, +5 authors, Keisuke Izumi.
Oncol Lett, 2010 Nov 01; 1(6). PMID: 22870098    Free PMC article.
Scenario drafting to anticipate future developments in technology assessment.
Valesca P Retèl, Manuela A Joore, +2 authors, Wim H van Harten.
BMC Res Notes, 2012 Aug 17; 5. PMID: 22894140    Free PMC article.
Analysis of and prognostic information from disseminated tumour cells in bone marrow in primary breast cancer: a prospective observational study.
Anna-Karin Falck, Pär-Ola Bendahl, +7 authors, Lisa Rydén.
BMC Cancer, 2012 Sep 12; 12. PMID: 22963449    Free PMC article.
High expression of thymidine phosphorylase in basal-like breast cancers: Stromal expression in EGFR- and/or CK5/6-positive breast cancers.
Shinobu Umemura, Masatoshi Shirane, +3 authors, Robert Y Osamura.
Oncol Lett, 2010 Mar 01; 1(2). PMID: 22966291    Free PMC article.
Accuracy validation of adjuvant! online in Taiwanese breast cancer patients--a 10-year analysis.
Kuo Yao-Lung, Chen Dar-Ren, Chang Tsai-Wang.
BMC Med Inform Decis Mak, 2012 Sep 19; 12. PMID: 22985190    Free PMC article.
Guidelines for locoregional therapy in primary breast cancer in developing countries: The results of an expert panel at the 8(th) Annual Women's Cancer Initiative - Tata Memorial Hospital (WCI-TMH) Conference.
Anusheel Munshi, Sudeep Gupta, +12 authors, other Locoregional Panel Members.
Indian J Med Paediatr Oncol, 2012 Sep 19; 33(2). PMID: 22988354    Free PMC article.
The effect of accompanying in situ ductal carcinoma on accuracy of measuring malignant breast tumor size using B-mode ultrasonography and real-time sonoelastography.
A A Soliman, S Wojcinski, F Degenhardt.
Int J Breast Cancer, 2012 Sep 19; 2012. PMID: 22988516    Free PMC article.
Ki-67 as a prognostic marker according to breast cancer subtype and a predictor of recurrence time in primary breast cancer.
Reiki Nishimura, Tomofumi Osako, +3 authors, Nobuyuki Arima.
Exp Ther Med, 2010 Sep 01; 1(5). PMID: 22993598    Free PMC article.
Comparison of evaluations of hormone receptors in breast carcinoma by image-analysis using three automated immunohistochemical stainings.
Koji Arihiro, Miyo Oda, +9 authors, Maiko Tanaka.
Exp Ther Med, 2010 Nov 01; 1(6). PMID: 22993620    Free PMC article.
Localization of decorin gene expression in normal human breast tissue and in benign and malignant tumors of the human breast.
Pia Boström, Annele Sainio, +3 authors, Hannu Järveläinen.
Histochem Cell Biol, 2012 Sep 26; 139(1). PMID: 23007289    Free PMC article.
Impact of premenopausal status at breast cancer diagnosis in women entered on the placebo-controlled NCIC CTG MA17 trial of extended adjuvant letrozole.
P E Goss, J N Ingle, +11 authors, D Tu.
Ann Oncol, 2012 Oct 03; 24(2). PMID: 23028039    Free PMC article.
EndoPredict improves the prognostic classification derived from common clinical guidelines in ER-positive, HER2-negative early breast cancer.
P Dubsky, M Filipits, +17 authors, Austrian Breast and Colorectal Cancer Study Group (ABCSG).
Ann Oncol, 2012 Oct 05; 24(3). PMID: 23035151    Free PMC article.
Open biomedical pluralism: formalising knowledge about breast cancer phenotypes.
Aleksandra Sojic, Oliver Kutz.
J Biomed Semantics, 2012 Oct 11; 3 Suppl 2. PMID: 23046572    Free PMC article.
Image and pathological changes after radiofrequency ablation of invasive breast cancer: a pilot study of nonsurgical therapy of early breast cancer.
Yasuteru Yoshinaga, Yasuko Enomoto, +3 authors, Akinori Iwasaki.
World J Surg, 2012 Oct 12; 37(2). PMID: 23052813
[Translational research and diagnostics for breast cancer].
H H Kreipe.
Pathologe, 2012 Oct 16; 33 Suppl 2. PMID: 23064514
Review.
Population-based study of breast cancer in older women: prognostic factors of relative survival and predictors of treatment.
Pegdwende Olivia Dialla, Tienhan Sandrine Dabakuyo, +6 authors, Patrick Arveux.
BMC Cancer, 2012 Oct 17; 12. PMID: 23066863    Free PMC article.
Patients' choice on axillary lymph node dissection following sentinel lymph node micrometastasis--first report on prospective use of a nomogram in very low risk patients.
Gábor Cserni, Istvánné Bezsenyi, László Markó.
Pathol Oncol Res, 2012 Oct 17; 19(2). PMID: 23070585
Impact of the american college of surgeons oncology group Z0011 criteria applied to a contemporary patient population.
Min Yi, Henry M Kuerer, +6 authors, Kelly K Hunt.
J Am Coll Surg, 2012 Nov 06; 216(1). PMID: 23122536    Free PMC article.
A model of estrogen-related gene expression reveals non-linear effects in transcriptional response to tamoxifen.
Galina Lebedeva, Azusa Yamaguchi, +2 authors, David J Harrison.
BMC Syst Biol, 2012 Nov 09; 6. PMID: 23134774    Free PMC article.
The 21-gene recurrence score assay impacts adjuvant therapy recommendations for ER-positive, node-negative and node-positive early breast cancer resulting in a risk-adapted change in chemotherapy use.
W Eiermann, M Rezai, +13 authors, J Blohmer.
Ann Oncol, 2012 Nov 09; 24(3). PMID: 23136233    Free PMC article.
Histone demethylase GASC1--a potential prognostic and predictive marker in invasive breast cancer.
Bozena Berdel, Kaisa Nieminen, +5 authors, Arto Mannermaa.
BMC Cancer, 2012 Nov 15; 12. PMID: 23148692    Free PMC article.
Adding hormonal therapy to chemotherapy and trastuzumab improves prognosis in patients with hormone receptor-positive and human epidermal growth factor receptor 2-positive primary breast cancer.
Naoki Hayashi, Naoki Niikura, +2 authors, Naoto T Ueno.
Breast Cancer Res Treat, 2012 Nov 28; 137(2). PMID: 23184079    Free PMC article.
Treatment when prognostic factors do not match St. Gallen recommendations: profiling of prognostic factors among HR(+) and HER2(-) breast cancer patients.
Kyoko Satoh, Maki Tanaka, +2 authors, Tatsuyuki Kakuma.
World J Surg, 2012 Dec 12; 37(3). PMID: 23229849
Optimizing surgical margins in breast conservation.
Preya Ananthakrishnan, Fatih Levent Balci, Joseph P Crowe.
Int J Surg Oncol, 2013 Jan 11; 2012. PMID: 23304479    Free PMC article.
Adjuvant Hormonal Therapy in Postmenopausal Women with Breast Cancer: Physician's Choices.
Asim Jamal Shaikh, Shiyam Kumar, +2 authors, Osama Ishtiaq.
Int J Breast Cancer, 2013 Jan 11; 2012. PMID: 23304528    Free PMC article.
Analysis of the potent prognostic factors in luminal-type breast cancer.
Han-Sung Kim, Inseok Park, +7 authors, Young-Duck Kim.
J Breast Cancer, 2013 Jan 25; 15(4). PMID: 23346168    Free PMC article.
The mitochondrial transport protein SLC25A43 affects drug efficacy and drug-induced cell cycle arrest in breast cancer cell lines.
Marike Gabrielson, Elisabet Tina.
Oncol Rep, 2013 Jan 29; 29(4). PMID: 23354756    Free PMC article.
Elevated BUBR1 expression is associated with poor survival in early breast cancer patients: 15-year follow-up analysis.
Adam Maciejczyk, Jolanta Szelachowska, +4 authors, Paweł Surowiak.
J Histochem Cytochem, 2013 Feb 09; 61(5). PMID: 23392733    Free PMC article.
Genomic and phenotypic profiles of two Brazilian breast cancer cell lines derived from primary human tumors.
Natássia C R Corrêa, Hellen Kuasne, +10 authors, Dawidson A Gomes.
Oncol Rep, 2013 Feb 14; 29(4). PMID: 23404580    Free PMC article.
Evidence produced in Japan: tegafur-based preparations for postoperative chemotherapy in breast cancer.
Toru Watanabe.
Breast Cancer, 2013 Mar 05; 20(4). PMID: 23456736    Free PMC article.
Review.
Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial.
Viviana Galimberti, Bernard F Cole, +25 authors, International Breast Cancer Study Group Trial 23-01 investigators.
Lancet Oncol, 2013 Mar 16; 14(4). PMID: 23491275    Free PMC article.
Highly Cited.
A dynamic clinical pathway for the treatment of patients with early breast cancer is a tool for better cancer care: implementation and prospective analysis between 2002-2010.
Peter A van Dam, Gerda Verheyden, +7 authors, Luc Dirix.
World J Surg Oncol, 2013 Mar 19; 11. PMID: 23497270    Free PMC article.
Long-term prognostic performance of Ki67 rate in early stage, pT1-pT2, pN0, invasive breast carcinoma.
Fabien Reyal, David Hajage, +14 authors, Xavier Sastre-Garau.
PLoS One, 2013 Mar 26; 8(3). PMID: 23526930    Free PMC article.
The combination of Ki67, histological grade and estrogen receptor status identifies a low-risk group among 1,854 chemo-naïve women with N0/N1 primary breast cancer.
Carina Strand, Martin Bak, +13 authors, Mårten Fernö.
Springerplus, 2013 Apr 06; 2(1). PMID: 23560250    Free PMC article.
Long-term analysis to objectify the tumour grading by means of automated microscopic image analysis of the nucleolar organizer regions (AgNORs) in the case of breast carcinoma.
Klaus-Jürgen Winzer, Joachim Bellach, Peter Hufnagl.
Diagn Pathol, 2013 Apr 10; 8. PMID: 23566354    Free PMC article.
Gene expression profiling in breast cancer.
Belisario A Arango, Celine L Rivera, Stefan Glück.
Am J Transl Res, 2013 Apr 11; 5(2). PMID: 23573359    Free PMC article.
Tailoring treatment for ductal intraepithelial neoplasia of the breast according to Ki-67 and molecular phenotype.
M Lazzeroni, A Guerrieri-Gonzaga, +12 authors, G Pruneri.
Br J Cancer, 2013 Apr 13; 108(8). PMID: 23579208    Free PMC article.
Fertility preservation in cancer survivors: a national survey of oncologists' current knowledge, practice and attitudes.
E Adams, E Hill, E Watson.
Br J Cancer, 2013 Apr 13; 108(8). PMID: 23579214    Free PMC article.
HER2-positive breast cancer patients receiving trastuzumab treatment obtain prognosis comparable with that of HER2-negative breast cancer patients.
Tao Qin, Zhongyu Yuan, +5 authors, Shusen Wang.
Onco Targets Ther, 2013 May 01; 6. PMID: 23630425    Free PMC article.
Identification and validation of a new set of five genes for prediction of risk in early breast cancer.
Giorgio Mustacchi, Maria Pia Sormani, +5 authors, Luca Morandi.
Int J Mol Sci, 2013 May 08; 14(5). PMID: 23648477    Free PMC article.
A randomized, double-blind, controlled study of exemestane versus anastrozole for the first-line treatment of postmenopausal Japanese women with hormone-receptor-positive advanced breast cancer.
Hiroji Iwata, Norikazu Masuda, +10 authors, Shinzaburo Noguchi.
Breast Cancer Res Treat, 2013 May 30; 139(2). PMID: 23715630    Free PMC article.
Multigene assays and molecular markers in breast cancer: systematic review of health economic analyses.
Roman Rouzier, Paolo Pronzato, +3 authors, William J Valentine.
Breast Cancer Res Treat, 2013 Jun 01; 139(3). PMID: 23722312    Free PMC article.
Systematic Review.
Association between genomic recurrence risk and well-being among breast cancer patients.
Valesca P Retèl, Catharina G M Groothuis-Oudshoorn, +3 authors, Wim H van Harten.
BMC Cancer, 2013 Jun 20; 13. PMID: 23777535    Free PMC article.
The EndoPredict Gene-Expression Assay in Clinical Practice - Performance and Impact on Clinical Decisions.
Berit Maria Müller, Elke Keil, +16 authors, Carsten Denkert.
PLoS One, 2013 Jul 05; 8(6). PMID: 23826382    Free PMC article.
Molecular subtypes, histopathological grade and survival in a historic cohort of breast cancer patients.
M J Engstrøm, S Opdahl, +5 authors, A M Bofin.
Breast Cancer Res Treat, 2013 Aug 01; 140(3). PMID: 23901018    Free PMC article.
Clinical relevance of lymph node ratio in breast cancer patients with one to three positive lymph nodes.
S I Kim, S-H Cho, +5 authors, B-W Park.
Br J Cancer, 2013 Aug 15; 109(5). PMID: 23942073    Free PMC article.
Genomic Grade Index (GGI): feasibility in routine practice and impact on treatment decisions in early breast cancer.
Otto Metzger-Filho, Aurélie Catteau, +21 authors, Christos Sotiriou.
PLoS One, 2013 Aug 31; 8(8). PMID: 23990869    Free PMC article.
Value of pre-treatment biomarkers in prediction of response to neoadjuvant endocrine therapy for hormone receptor-positive postmenopausal breast cancer.
Min Ying, Yingjian He, +7 authors, Tao Ouyang.
Chin J Cancer Res, 2013 Sep 03; 25(4). PMID: 23997526    Free PMC article.
St. Gallen 2013: brief preliminary summary of the consensus discussion.
Nadia Harbeck, Christoph Thomssen, Michael Gnant.
Breast Care (Basel), 2013 Sep 04; 8(2). PMID: 24000280    Free PMC article.
Clinical relevance of the reappraisal of negative hormone receptor expression in breast cancer.
António E Pinto, Filipa Areia, +5 authors, Saudade André.
Springerplus, 2013 Sep 07; 2. PMID: 24010033    Free PMC article.
Role of maximum standardized uptake value in fluorodeoxyglucose positron emission tomography/computed tomography predicts malignancy grade and prognosis of operable breast cancer: a multi-institute study.
Takayuki Kadoya, Kenjiro Aogi, +3 authors, Morihito Okada.
Breast Cancer Res Treat, 2013 Sep 13; 141(2). PMID: 24026860    Free PMC article.
Effect of chemotherapy for luminal a breast cancer.
Naotaka Uchida, Takako Suda, Kiyosuke Ishiguro.
Yonago Acta Med, 2013 Sep 14; 56(2). PMID: 24031152    Free PMC article.
Impact of SOX18 expression in cancer cells and vessels on the outcome of invasive ductal breast carcinoma.
Bartosz Pula, Mateusz Olbromski, +5 authors, Marzena Podhorska-Okolow.
Cell Oncol (Dordr), 2013 Sep 26; 36(6). PMID: 24065215
The EANM and SNMMI practice guideline for lymphoscintigraphy and sentinel node localization in breast cancer.
Francesco Giammarile, Naomi Alazraki, +10 authors, Sergi Vidal Sicart.
Eur J Nucl Med Mol Imaging, 2013 Oct 03; 40(12). PMID: 24085499
The use of digital images improves reproducibility of the ki-67 labeling index as a proliferation marker in breast cancer.
András Vörös, Erika Csörgő, +3 authors, Gábor Cserni.
Pathol Oncol Res, 2013 Nov 10; 20(2). PMID: 24202856
Effect of prior chemotherapy regimens on the efficacy of endocrine therapy within a German cohort of the TEAM trial.
Michaela Bossart, Peyman Hadji, +2 authors, Annette Hasenburg.
J Cancer Res Clin Oncol, 2013 Nov 26; 140(1). PMID: 24271056
St Gallen molecular subtypes in primary breast cancer and matched lymph node metastases--aspects on distribution and prognosis for patients with luminal A tumours: results from a prospective randomised trial.
Anna-Karin Falck, Mårten Fernö, Pär-Ola Bendahl, Lisa Rydén.
BMC Cancer, 2013 Nov 28; 13. PMID: 24274821    Free PMC article.
Significance of micrometastases: circulating tumor cells and disseminated tumor cells in early breast cancer.
Catherine Oakman, Marta Pestrin, +2 authors, Angelo Di Leo.
Cancers (Basel), 2010 Jan 01; 2(2). PMID: 24281114    Free PMC article.
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.
Suzanne A Eccles, Eric O Aboagye, +84 authors, Alastair M Thompson.
Breast Cancer Res, 2013 Nov 30; 15(5). PMID: 24286369    Free PMC article.
Highly Cited. Review.
Weakly hormone receptor-positive breast cancer and use of adjuvant hormonal therapy.
Cassandra M Lin, Jasbir Jaswal, +2 authors, Muriel Brackstone.
Curr Oncol, 2013 Dec 07; 20(6). PMID: 24311965    Free PMC article.
Post-mastectomy radiotherapy for breast cancer patients with t1-t2 and 1-3 positive lymph nodes: a meta-analysis.
Yaming Li, Meena S Moran, +2 authors, Bruce G Haffty.
PLoS One, 2013 Dec 07; 8(12). PMID: 24312582    Free PMC article.
CYP19 genetic polymorphism haplotype AASA is associated with a poor prognosis in premenopausal women with lymph node-negative, hormone receptor-positive breast cancer.
Sung-Hsin Kuo, Shi-Yi Yang, +6 authors, Chiun-Sheng Huang.
Biomed Res Int, 2013 Dec 11; 2013. PMID: 24324964    Free PMC article.
Metabolism and transport of tamoxifen in relation to its effectiveness: new perspectives on an ongoing controversy.
Deirdre P Cronin-Fenton, Per Damkier, Timothy L Lash.
Future Oncol, 2013 Dec 18; 10(1). PMID: 24328412    Free PMC article.
Review.
Semi-automated evaluation of Ki-67 index in invasive ductal carcinoma of the breast.
Cristian Suciu, Anca Muresan, +3 authors, Marius Raica.
Oncol Lett, 2013 Dec 19; 7(1). PMID: 24348830    Free PMC article.
Aromatase inhibitor-associated bone loss and its management with bisphosphonates in patients with breast cancer.
M Bauer, J Bryce, P Hadji.
Breast Cancer (Dove Med Press), 2012 Jan 01; 4. PMID: 24367197    Free PMC article.
Review.
Complementary or alternative medicine as possible determinant of decreased persistence to aromatase inhibitor therapy among older women with non-metastatic breast cancer.
Laetitia Huiart, Anne-Deborah Bouhnik, +6 authors, Roch Giorgi.
PLoS One, 2013 Dec 25; 8(12). PMID: 24367488    Free PMC article.
Estrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast cancer cells.
I Moy, V Todorović, +7 authors, S E Bulun.
Oncogene, 2014 Jan 15; 34(3). PMID: 24413080    Free PMC article.
[Determination of proliferation in breast cancer by immunohistochemical detection of Ki-67].
M Christgen, W Winkens, H H Kreipe.
Pathologe, 2014 Jan 15; 35(1). PMID: 24414612
Prognostic value of Ki-67 in breast cancer patients with positive axillary lymph nodes: a retrospective cohort study.
Feng-yan Li, San-gang Wu, +5 authors, Zhen-yu He.
PLoS One, 2014 Feb 06; 9(2). PMID: 24498305    Free PMC article.
Do the derived neutrophil to lymphocyte ratio and the neutrophil to lymphocyte ratio predict prognosis in breast cancer?
Ahmet Dirican, Betul Bolat Kucukzeybek, +13 authors, Mustafa Oktay Tarhan.
Int J Clin Oncol, 2014 Feb 18; 20(1). PMID: 24532163
Invasive lobular carcinoma of the breast: long-term prognostic value of Ki67 and histological grade, alone and in combination with estrogen receptor.
Ulrik Narbe, Pär-Ola Bendahl, +3 authors, Mårten Fernö.
Springerplus, 2014 Feb 26; 3. PMID: 24567879    Free PMC article.
Determinants of newly diagnosed comorbidities among breast cancer survivors.
Nadia Obi, Daniela Gornyk, +4 authors, Dieter Flesch-Janys.
J Cancer Surviv, 2014 Feb 27; 8(3). PMID: 24570215
Clinicopathologic features of triple negative breast cancers: an experience from Pakistan.
Atif Ali Hashmi, Muhammad Muzzammil Edhi, +3 authors, Mehmood Khan.
Diagn Pathol, 2014 Mar 04; 9. PMID: 24581278    Free PMC article.
Nottingham Prognostic Index Plus (NPI+): a modern clinical decision making tool in breast cancer.
E A Rakha, D Soria, +6 authors, I O Ellis.
Br J Cancer, 2014 Mar 13; 110(7). PMID: 24619074    Free PMC article.
Multi-level gene expression signatures, but not binary, outperform Ki67 for the long term prognostication of breast cancer patients.
Nicholas P Tobin, Linda S Lindström, +3 authors, Kristian Wennmalm.
Mol Oncol, 2014 Mar 19; 8(3). PMID: 24630985    Free PMC article.
Comparative assessment of the estrogen receptor β expression in the tissues of non-small cell lung carcinoma and lung metastases of tumors of other primary localizations.
T A Bogush, A S Shaturova, +4 authors, M I Davydov.
Dokl Biochem Biophys, 2014 Mar 19; 454(1). PMID: 24633609
Collagen gel droplet-embedded culture-drug sensitivity test and Ki67 expression in estrogen receptor-positive and HER2-negative breast cancer.
Katsunori Tozuka, Jun Horiguchi, +7 authors, Izumi Takeyoshi.
Mol Clin Oncol, 2013 Jan 01; 1(1). PMID: 24649129    Free PMC article.
Clinical utility of aromatase inhibitors as adjuvant treatment in postmenopausal early breast cancer.
Arturo Loaiza-Bonilla, Francisco Socola, Stefan Glück.
Clin Med Insights Womens Health, 2013 Jan 01; 6. PMID: 24665209    Free PMC article.
Review.
Correlation between three-dimensional ultrasound features and pathological prognostic factors in breast cancer.
Jun Jiang, Ya-qing Chen, +4 authors, Xiao-jin Wang.
Eur Radiol, 2014 Apr 12; 24(6). PMID: 24723231
The effect of laterality and primary tumor site on cancer-specific mortality in breast cancer: a SEER population-based study.
Jing Bao, Ke-Da Yu, +2 authors, Gen-Hong Di.
PLoS One, 2014 Apr 18; 9(4). PMID: 24740002    Free PMC article.
Intratumoral CD8⁺ cytotoxic lymphocyte is a favorable prognostic marker in node-negative breast cancer.
Zonglin Chen, Xianyu Chen, +5 authors, Zhonghua Tang.
PLoS One, 2014 Apr 20; 9(4). PMID: 24743335    Free PMC article.
Interdisciplinary GoR level III Guidelines for the Diagnosis, Therapy and Follow-up Care of Breast Cancer: Short version - AWMF Registry No.: 032-045OL AWMF-Register-Nummer: 032-045OL - Kurzversion 3.0, Juli 2012.
R Kreienberg, U-S Albert, +3 authors, A Wöckel.
Geburtshilfe Frauenheilkd, 2014 Apr 29; 73(6). PMID: 24771925    Free PMC article.
Multigene Assays for Classification, Prognosis, and Prediction in Breast Cancer: a Critical Review on the Background and Clinical Utility.
P Sinn, S Aulmann, +6 authors, A Schneeweiss.
Geburtshilfe Frauenheilkd, 2014 Apr 29; 73(9). PMID: 24771945    Free PMC article.
Cdc20 and securin overexpression predict short-term breast cancer survival.
H Karra, H Repo, +6 authors, P Kronqvist.
Br J Cancer, 2014 May 24; 110(12). PMID: 24853182    Free PMC article.
Different methods of pretreatment Ki-67 labeling index evaluation in core biopsies of breast cancer patients treated with neoadjuvant chemotherapy and their relation to response to therapy.
András Vörös, Erika Csörgő, +5 authors, Gábor Cserni.
Pathol Oncol Res, 2014 May 27; 21(1). PMID: 24859973
DEGRO practical guidelines for radiotherapy of breast cancer IV: radiotherapy following mastectomy for invasive breast cancer.
Frederik Wenz, Elena Sperk, +12 authors, Breast Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO).
Strahlenther Onkol, 2014 Jun 04; 190(8). PMID: 24888511
Factors associated to persistence with hormonal therapy in women with breast cancer.
Cláudia Brito, Margareth Crisóstomo Portela, Mauricio Teixeira Leite de Vasconcellos.
Rev Saude Publica, 2014 Jun 05; 48(2). PMID: 24897050    Free PMC article.
Novel serum protein biomarker panel revealed by mass spectrometry and its prognostic value in breast cancer.
Liping Chung, Katrina Moore, +3 authors, Robert C Baxter.
Breast Cancer Res, 2014 Jun 18; 16(3). PMID: 24935269    Free PMC article.
Luminal breast cancer classification according to proliferative indices: clinicopathological characteristics and short-term survival analysis.
Yan Sun, Gang Nie, +3 authors, Haibo Wang.
Med Oncol, 2014 Jun 18; 31(7). PMID: 24935624
The multigene signature MammaPrint impacts on multidisciplinary team decisions in ER+, HER2- early breast cancer.
R Exner, Z Bago-Horvath, +9 authors, P Dubsky.
Br J Cancer, 2014 Jul 09; 111(5). PMID: 25003667    Free PMC article.
Differential expression of miR-139, miR-486 and miR-21 in breast cancer patients sub-classified according to lymph node status.
Lene Rask, Eva Balslev, +4 authors, Thomas Litman.
Cell Oncol (Dordr), 2014 Jul 17; 37(3). PMID: 25027758
Postmastectomy radiotherapy for locally advanced breast cancer receiving neoadjuvant chemotherapy.
Icro Meattini, Sara Cecchini, +13 authors, Lorenzo Livi.
Biomed Res Int, 2014 Jul 22; 2014. PMID: 25045694    Free PMC article.
Tumour cell proliferation (Ki-67) in non-small cell lung cancer: a critical reappraisal of its prognostic role.
A Warth, J Cortis, +12 authors, W Weichert.
Br J Cancer, 2014 Jul 23; 111(6). PMID: 25051406    Free PMC article.
Aromatase inhibitors associated musculoskeletal disorders and bone fractures in postmenopausal breast cancer patients: a result from Chinese population.
Lu Xu, Jue Wang, Dan-Dan Xue, Wei He.
Med Oncol, 2014 Jul 25; 31(9). PMID: 25056205
Prognostic value of ki-67 in breast carcinoma: tissue microarray method versus whole section analysis- potentials and pitfalls.
Natalija Dedić Plavetić, Jasminka Jakić-Razumović, +3 authors, Damir Vrbanec.
Pathol Oncol Res, 2014 Aug 07; 21(2). PMID: 25096394
Trends and present treatment patterns of early breast cancer in Southwest China.
Qiancheng Hu, Ting Luo, +5 authors, Hong Zheng.
Pathol Oncol Res, 2014 Aug 07; 21(2). PMID: 25096396
A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.
Hans Kristian Moen Vollan, Oscar M Rueda, +22 authors, Carlos Caldas.
Mol Oncol, 2014 Aug 30; 9(1). PMID: 25169931    Free PMC article.
Immunohistochemical detection improves the prognostic value of lymphatic and blood vessel invasion in primary ductal breast cancer.
Fadia J A Gujam, James J Going, +3 authors, Donald C McMillan.
BMC Cancer, 2014 Sep 23; 14. PMID: 25234410    Free PMC article.
Prognostic significance of Ki-67 index value at the primary breast tumor in recurrent breast cancer.
Reiki Nishimura, Tomofumi Osako, +5 authors, Nobuyuki Arima.
Mol Clin Oncol, 2014 Oct 04; 2(6). PMID: 25279198    Free PMC article.
Genetic variants of kinase suppressors of Ras (KSR1) to predict survival in patients with ERα-positive advanced breast cancer.
L Benhaim, W Zhang, +14 authors, H J Lenz.
Pharmacogenomics J, 2014 Oct 08; 15(3). PMID: 25287073
Receptor conversion in carcinoma breast metastatic to the bone marrow.
T Santosh, M K Patro, +4 authors, D P Mishra.
Indian J Hematol Blood Transfus, 2014 Oct 22; 30(Suppl 1). PMID: 25332613    Free PMC article.
Update on adjuvant chemotherapy for early breast cancer.
Murtuza M Rampurwala, Gabrielle B Rocque, Mark E Burkard.
Breast Cancer (Auckl), 2014 Oct 23; 8. PMID: 25336961    Free PMC article.
Review.
Prognosis in very young women with triple-negative breast cancer: retrospective study of 216 cases.
Ying Liu, Tao Xin, +7 authors, Qiu-ying Jiang.
Med Oncol, 2014 Nov 14; 31(12). PMID: 25391919
Imaging tumour heterogeneity of the consequences of a PKCα-substrate interaction in breast cancer patients.
Gregory Weitsman, Katherine Lawler, +18 authors, Tony Ng.
Biochem Soc Trans, 2014 Nov 18; 42(6). PMID: 25399560    Free PMC article.
Review.
Nordamnacanthal potentiates the cytotoxic effects of tamoxifen in human breast cancer cells.
Tamilselvan Subramani, Swee Keong Yeap, +5 authors, Noorjahan Banu Alitheen.
Oncol Lett, 2014 Dec 02; 9(1). PMID: 25435988    Free PMC article.
BP-C1 in the treatment of patients with stage IV breast cancer: a randomized, double-blind, placebo-controlled multicenter study and an additional open-label treatment phase.
Stig Larsen, Kritiya Butthongkomvong, +5 authors, Steen Lindkær-Jensen.
Breast Cancer (Dove Med Press), 2014 Dec 05; 6. PMID: 25473312    Free PMC article.
Heterogeneity in hormone-receptor status and survival outcomes among women with synchronous and metachronous bilateral breast cancers.
Zora Baretta, Olufunmilayo I Olopade, Dezheng Huo.
Breast, 2014 Dec 24; 24(2). PMID: 25534718    Free PMC article.
Exploring the spatial dimension of estrogen and progesterone signaling: detection of nuclear labeling in lobular epithelial cells in normal mammary glands adjacent to breast cancer.
Anne Grote, Mahmoud Abbas, +3 authors, Friedrich Feuerhake.
Diagn Pathol, 2015 Jan 08; 9 Suppl 1. PMID: 25565114    Free PMC article.
Predicting fatigue in older breast cancer patients receiving radiotherapy. A head-to-head comparison of established assessments.
Michael Dieter Denkinger, Melanie Hasch, +3 authors, Katharina Hancke.
Z Gerontol Geriatr, 2015 Jan 17; 48(2). PMID: 25592175
Triple-negative breast cancer: new perspectives for targeted therapies.
Federica Tomao, Anselmo Papa, +6 authors, Silverio Tomao.
Onco Targets Ther, 2015 Feb 06; 8. PMID: 25653541    Free PMC article.
Highly Cited. Review.
A randomized controlled study evaluating safety and efficacy of leuprorelin acetate every-3-months depot for 2 versus 3 or more years with tamoxifen for 5 years as adjuvant treatment in premenopausal patients with endocrine-responsive breast cancer.
Eiichi Shiba, Hiroko Yamashita, +5 authors, Tsukasa Fujimoto.
Breast Cancer, 2015 Feb 07; 23(3). PMID: 25655898    Free PMC article.
Common 4977 bp deletion and novel alterations in mitochondrial DNA in Vietnamese patients with breast cancer.
Jan Dimberg, Thai Trinh Hong, +3 authors, Andreas Matussek.
Springerplus, 2015 Feb 13; 4. PMID: 25674508    Free PMC article.
Strong adverse effect of epidermal growth factor receptor 2 overexpression on prognosis of patients with invasive lobular breast cancer: a comparative study with invasive ductal breast cancer in Chinese population.
Tong Wang, Yuanyuan Ma, +3 authors, Ruifang Niu.
Tumour Biol, 2015 Mar 26; 36(8). PMID: 25804795
Sentinel lymph node biopsy (SLNB) vs. axillary lymph node dissection (ALND) in the current surgical treatment of early stage breast cancer.
M Gherghe, C Bordea, A Blidaru.
J Med Life, 2015 Apr 14; 8(2). PMID: 25866575    Free PMC article.
Poor prognosis of single hormone receptor- positive breast cancer: similar outcome as triple-negative breast cancer.
Soo Youn Bae, Sangmin Kim, +6 authors, Seok Jin Nam.
BMC Cancer, 2015 Apr 17; 15. PMID: 25880075    Free PMC article.
Macroscopic optical physiological parameters correlate with microscopic proliferation and vessel area breast cancer signatures.
So Hyun Chung, Michael D Feldman, +10 authors, Regine Choe.
Breast Cancer Res, 2015 May 28; 17. PMID: 26013572    Free PMC article.
Magnetic resonance imaging texture analysis classification of primary breast cancer.
S A Waugh, C A Purdie, +4 authors, A M Thompson.
Eur Radiol, 2015 Jun 13; 26(2). PMID: 26065395
Using proliferative markers and Oncotype DX in therapeutic decision-making for breast cancer: the B.C. experience.
E Baxter, L Gondara, +5 authors, S Tyldesley.
Curr Oncol, 2015 Jun 20; 22(3). PMID: 26089718    Free PMC article.
Quantitation of the Regional Lymph Node Metastatic Burden and Prognosis in Malignant Mammary Tumors of Dogs.
M R de Araújo, L C Campos, E Ferreira, G D Cassali.
J Vet Intern Med, 2015 Jul 02; 29(5). PMID: 26130166    Free PMC article.
Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance.
Loredana Vesci, Valeria Carollo, +4 authors, Rita De Santis.
Oncol Rep, 2015 Jul 03; 34(3). PMID: 26133490    Free PMC article.
Application status of tamoxifen in endocrine therapy for early breast cancer.
Qiancheng Hu, Ting Luo, +3 authors, Hong Zheng.
Exp Ther Med, 2015 Jul 03; 9(6). PMID: 26136961    Free PMC article.
Application of a 70-Gene Expression Profile to Japanese Breast Cancer Patients.
Hideo Shimizu, Yoshiya Horimoto, +14 authors, Mitsue Saito.
Breast Care (Basel), 2015 Jul 22; 10(2). PMID: 26195940    Free PMC article.
Digital imaging in the immunohistochemical evaluation of the proliferation markers Ki67, MCM2 and Geminin, in early breast cancer, and their putative prognostic value.
Shalaka Joshi, Johnathan Watkins, +4 authors, Sarah E Pinder.
BMC Cancer, 2015 Jul 25; 15. PMID: 26205655    Free PMC article.
Decreased hormonal sensitivity after childbirth rather than the tumor size influences the prognosis of very young breast cancer patients.
Masujiro Makita, Takehiko Sakai, +17 authors, Takuji Iwase.
Springerplus, 2015 Jul 25; 4. PMID: 26207196    Free PMC article.
Relative Effectiveness of Letrozole Compared With Tamoxifen for Patients With Lobular Carcinoma in the BIG 1-98 Trial.
Otto Metzger Filho, Anita Giobbie-Hurder, +12 authors, Aron Goldhirsch.
J Clin Oncol, 2015 Jul 29; 33(25). PMID: 26215945    Free PMC article.
Protease Activated Receptors 1 and 2 Correlate Differently with Breast Cancer Aggressiveness Depending on Tumor ER Status.
Jon Lidfeldt, Pär-Ola Bendahl, +3 authors, Mattias Belting.
PLoS One, 2015 Aug 06; 10(8). PMID: 26244666    Free PMC article.
Predicting benefit of endocrine therapy for early breast cancer.
Meredith M Regan.
Breast, 2015 Aug 10; 24 Suppl 2. PMID: 26255197    Free PMC article.
Outcomes of special histotypes of breast cancer after adjuvant endocrine therapy with letrozole or tamoxifen in the monotherapy cohort of the BIG 1-98 trial.
E Munzone, A Giobbie-Hurder, +13 authors, International Breast Cancer Study Group and the BIG 1-98 Collaborative Group.
Ann Oncol, 2015 Sep 21; 26(12). PMID: 26387144    Free PMC article.
Predictive value and clinical utility of centrally assessed ER, PgR, and Ki-67 to select adjuvant endocrine therapy for premenopausal women with hormone receptor-positive, HER2-negative early breast cancer: TEXT and SOFT trials.
Meredith M Regan, Olivia Pagani, +21 authors, SOFT and TEXT Investigators and International Breast Cancer Study Group.
Breast Cancer Res Treat, 2015 Oct 24; 154(2). PMID: 26493064    Free PMC article.
LINC00472 expression is regulated by promoter methylation and associated with disease-free survival in patients with grade 2 breast cancer.
Yi Shen, Zhanwei Wang, +6 authors, Herbert Yu.
Breast Cancer Res Treat, 2015 Nov 14; 154(3). PMID: 26564482    Free PMC article.
The Role of Androgen Receptor in Breast Cancer.
Domenico Iacopetta, Yassine Rechoum, Suzanne Aw Fuqua.
Drug Discov Today Dis Mech, 2012 Jul 01; 9(1-2). PMID: 26568765    Free PMC article.
The Performance of the Nottingham Prognosis Index and the Adjuvant Online Decision Making Tool for Prognosis in Early-stage Breast Cancer Patients.
Mehri Rejali, Mehdi Tazhibi, +2 authors, Reyhane Mokarian.
Int J Prev Med, 2015 Nov 26; 6. PMID: 26605014    Free PMC article.
Sentinel lymph node biopsy in patients with breast ductal carcinoma in situ: Chinese experiences.
Xiao Sun, Hao Li, +7 authors, Yong-Sheng Wang.
Oncol Lett, 2015 Dec 02; 10(3). PMID: 26622778    Free PMC article.
Hormone receptor status predicts the clinical outcome of human epidermal growth factor 2-positive metastatic breast cancer patients receiving trastuzumab therapy: a multicenter retrospective study.
Yunchao Wang, Tao Sun, +5 authors, Janice Lu.
Onco Targets Ther, 2015 Dec 10; 8. PMID: 26648738    Free PMC article.
The search for optimal cutoff points for apoptosis and proliferation rate in prognostification of early stage breast cancer patients treated with anthracyclines in adjuvant settings.
Beata Biesaga, Joanna Niemiec, +2 authors, Marek Ziobro.
Tumour Biol, 2015 Dec 22; 37(6). PMID: 26687650
The variation and clinical significance of hormone receptors and Her-2 status from primary to metastatic lesions in breast cancer patients.
Yan-Yun Zhu, Wen Si, +3 authors, Jun-Lan Yang.
Tumour Biol, 2015 Dec 22; 37(6). PMID: 26687919
Modulation of Tamoxifen Cytotoxicity by Caffeic Acid Phenethyl Ester in MCF-7 Breast Cancer Cells.
Tarek K Motawi, Samy A Abdelazim, +2 authors, Samia A Shouman.
Oxid Med Cell Longev, 2015 Dec 24; 2016. PMID: 26697130    Free PMC article.
The role of postmastectomy radiotherapy in clinically node-positive, stage II-III breast cancer patients with pathological negative nodes after neoadjuvant chemotherapy: an analysis from the NCDB.
Jieqiong Liu, Kai Mao, +5 authors, Lisa K Jacobs.
Oncotarget, 2015 Dec 29; 7(17). PMID: 26709538    Free PMC article.
Prognostic impact of progesterone receptor status combined with body mass index in breast cancer patients treated with adjuvant aromatase inhibitor.
Masahiro Ohara, Etsushi Akimoto, +4 authors, Toshiyuki Itamoto.
Oncol Lett, 2016 Jan 02; 10(5). PMID: 26722327    Free PMC article.
Analysis of informativeness of immunohistochemical and flow cytometric methods for estrogen receptor α assessment.
T A Bogush, E A Dudko, +4 authors, I K Vorotnikov.
Dokl Biochem Biophys, 2016 Jan 06; 465. PMID: 26728725
Fibroblast growth factor receptor-1 protein expression is associated with prognosis in estrogen receptor-positive/human epidermal growth factor receptor-2-negative primary breast cancer.
Mai Tomiguchi, Yutaka Yamamoto, +8 authors, Hirotaka Iwase.
Cancer Sci, 2016 Jan 24; 107(4). PMID: 26801869    Free PMC article.
The association of subtypes of breast cancer with tumour characteristics and reproductive factors in 1326 Mexican women.
Gabriel Pérez-Rodríguez, Catalina Aranda-Moreno, Ivonne M Olivares-Corichi, Jose R Garcia-Sanchez.
Contemp Oncol (Pozn), 2016 Feb 05; 19(6). PMID: 26843843    Free PMC article.
St Gallen molecular subtypes in screening-detected and symptomatic breast cancer in a prospective cohort with long-term follow-up.
A K Falck, A Röme, +4 authors, L Rydén.
Br J Surg, 2016 Feb 10; 103(5). PMID: 26856820    Free PMC article.
Comparisons between glucose analogue 2-deoxy-2-((18)F)fluoro-D-glucose and (18)F-sodium fluoride positron emission tomography/computed tomography in breast cancer patients with bone lesions.
Selene Capitanio, Francesca Bongioanni, +13 authors, Silvia Morbelli.
World J Radiol, 2016 Mar 17; 8(2). PMID: 26981229    Free PMC article.
Prognostic implications of securin expression and sub-cellular localization in human breast cancer.
N Gurvits, H Repo, +5 authors, P Kronqvist.
Cell Oncol (Dordr), 2016 Mar 18; 39(4). PMID: 26984614
Comparison of prognoses according to non-positive and positive spectrin αII expression detected immunohistochemically in epithelial ovarian carcinoma: a retrospective study.
Osamu Maeda, Tomoko Miyata-Takata, +6 authors, Fumitaka Kikkawa.
Cancer Med, 2016 Mar 20; 5(6). PMID: 26993048    Free PMC article.
Efficacy and safety of leuprorelin acetate 6-month depot, TAP-144-SR (6M), in combination with tamoxifen in postoperative, premenopausal patients with hormone receptor-positive breast cancer: a phase III, randomized, open-label, parallel-group comparative study.
Junichi Kurebayashi, Tatsuya Toyama, +2 authors, Tsukasa Fujimoto.
Breast Cancer, 2016 Mar 28; 24(1). PMID: 27017207    Free PMC article.
Automated quantification of proliferation with automated hot-spot selection in phosphohistone H3/MART1 dual-stained stage I/II melanoma.
Patricia Switten Nielsen, Rikke Riber-Hansen, Henrik Schmidt, Torben Steiniche.
Diagn Pathol, 2016 Apr 12; 11. PMID: 27062658    Free PMC article.
Genetics and Breast Cancer - Oncologists Perspectives.
Radheshyam Naik, Vidya Harini Veldore, Kodaganur S Gopinath.
Indian J Surg Oncol, 2016 Apr 12; 6(4). PMID: 27065667    Free PMC article.
Review.
Prognostic value of Ki67 and p53 in patients with estrogen receptor-positive and human epidermal growth factor receptor 2-negative breast cancer: Validation of the cut-off value of the Ki67 labeling index as a predictive factor.
Masahiro Ohara, Kazuo Matsuura, +5 authors, Toshiyuki Itamoto.
Mol Clin Oncol, 2016 Apr 14; 4(4). PMID: 27073684    Free PMC article.
The distribution pattern of ERα expression, ESR1 genetic variation and expression of growth factor receptors: association with breast cancer prognosis in Russian patients treated with adjuvant tamoxifen.
Nataliya Babyshkina, Sergey Vtorushin, +7 authors, Evgeny Choynzonov.
Clin Exp Med, 2016 May 27; 17(3). PMID: 27225751
Triple-negative breast cancer: treatment challenges and solutions.
Joëlle Collignon, Laurence Lousberg, Hélène Schroeder, Guy Jerusalem.
Breast Cancer (Dove Med Press), 2016 Jun 11; 8. PMID: 27284266    Free PMC article.
Highly Cited.
Prolactin-induced protein as a potential therapy response marker of adjuvant chemotherapy in breast cancer patients.
Karolina Jablonska, Jedrzej Grzegrzolka, +10 authors, Piotr Dziegiel.
Am J Cancer Res, 2016 Jun 14; 6(5). PMID: 27293986    Free PMC article.
An international study comparing conventional versus mRNA level testing (TargetPrint) for ER, PR, and HER2 status of breast cancer.
Jelle Wesseling, Corrado Tinterri, +16 authors, Pino Cusumano.
Virchows Arch, 2016 Jul 06; 469(3). PMID: 27377889
Expression and methylation patterns partition luminal-A breast tumors into distinct prognostic subgroups.
Dvir Netanely, Ayelet Avraham, +2 authors, Ron Shamir.
Breast Cancer Res, 2016 Jul 09; 18(1). PMID: 27386846    Free PMC article.
Assessment of dual-probe Her-2 fluorescent in situ hybridization in breast cancer by the 2013 ASCO/CAP guidelines produces more equivocal results than that by the 2007 ASCO/CAP guidelines.
Xiao-Long Qian, Hannah Y Wen, +6 authors, Li Fu.
Breast Cancer Res Treat, 2016 Jul 28; 159(1). PMID: 27455837    Free PMC article.
Identification of novel biomarkers associated with poor patient outcomes in invasive breast carcinoma.
Renata A Canevari, Fabio A Marchi, +5 authors, Eduardo M Reis.
Tumour Biol, 2016 Aug 04; 37(10). PMID: 27485113
Factors that predict recurrence later than 5 years after initial treatment in operable breast cancer.
Pattaraporn Wangchinda, Suthinee Ithimakin.
World J Surg Oncol, 2016 Aug 26; 14(1). PMID: 27557635    Free PMC article.
Risk factors for seroma evacuation in breast cancer patients treated with intraoperative radiotherapy.
Michał Falco, Bartłomiej Masojć, +6 authors, Andrzej Kram.
Rep Pract Oncol Radiother, 2016 Sep 08; 21(3). PMID: 27601955    Free PMC article.
From High-Throughput Microarray-Based Screening to Clinical Application: The Development of a Second Generation Multigene Test for Breast Cancer Prognosis.
Jan C Brase, Ralf Kronenwett, +2 authors, Marcus Schmidt.
Microarrays (Basel), 2013 Jan 01; 2(3). PMID: 27605191    Free PMC article.
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Prognostic values of negative estrogen or progesterone receptor expression in patients with luminal B HER2-negative breast cancer.
Chansub Park, Kyeongmee Park, +8 authors, Geumhee Gwak.
World J Surg Oncol, 2016 Sep 14; 14(1). PMID: 27619909    Free PMC article.
Young adult breast cancer patients have a poor prognosis independent of prognostic clinicopathological factors: a study from the Japanese Breast Cancer Registry.
Akemi Kataoka, Takayuki Iwamoto, +16 authors, Yutaka Tokuda.
Breast Cancer Res Treat, 2016 Sep 21; 160(1). PMID: 27647460    Free PMC article.
Breast cancer classification and prognostication through diverse systems along with recent emerging findings in this respect; the dawn of new perspectives in the clinical applications.
Vida Pourteimoor, Samira Mohammadi-Yeganeh, Mahdi Paryan.
Tumour Biol, 2016 Sep 22; 37(11). PMID: 27651157
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The combined endocrine receptor in breast cancer, a novel approach to traditional hormone receptor interpretation and a better discriminator of outcome than ER and PR alone.
Esther J Campbell, Mathias Tesson, +3 authors, Joanne Edwards.
Br J Cancer, 2016 Sep 23; 115(8). PMID: 27657341    Free PMC article.
Trends in Neoadjuvant Endocrine Therapy Use and Impact on Rates of Breast Conservation in Hormone Receptor-Positive Breast Cancer: A National Cancer Data Base Study.
Akiko Chiba, Tanya L Hoskin, +3 authors, Judy C Boughey.
Ann Surg Oncol, 2016 Sep 25; 24(2). PMID: 27663568    Free PMC article.
Changes in chemotherapy usage and outcome of early breast cancer patients in the last decade.
A Hennigs, F Riedel, +9 authors, A Schneeweiss.
Breast Cancer Res Treat, 2016 Nov 03; 160(3). PMID: 27744486    Free PMC article.
Prognostic significance of mucin expression profiles in breast carcinoma with signet ring cells: a clinicopathological study.
Ryuji Ohashi, Ayako Hayama, +4 authors, Zenya Naito.
Diagn Pathol, 2016 Nov 17; 11(1). PMID: 27846863    Free PMC article.
FISH testing of HER2 immunohistochemistry 1+ invasive breast cancer with unfavorable characteristics.
Stella Petroni, Lucia Caldarola, +4 authors, Giovanni Simone.
Oncol Lett, 2016 Dec 03; 12(5). PMID: 27899970    Free PMC article.
Intraoperative diagnosis of sentinel lymph node metastases in breast cancer treatment with one-step nucleic acid amplification assay (OSNA).
Paweł Szychta, Bogusław Westfal, +4 authors, Marek Zadrożny.
Arch Med Sci, 2016 Dec 03; 12(6). PMID: 27904514    Free PMC article.
Computational prediction of multidisciplinary team decision-making for adjuvant breast cancer drug therapies: a machine learning approach.
Frank P Y Lin, Adrian Pokorny, +2 authors, Richard J Epstein.
BMC Cancer, 2016 Dec 03; 16(1). PMID: 27905893    Free PMC article.
Factors Influencing Decision-Making for or against Adjuvant and Neoadjuvant Chemotherapy in Postmenopausal Hormone Receptor-Positive Breast Cancer Patients in the EvAluate-TM Study.
Paul Gaß, Peter A Fasching, +47 authors, Christian R Löhberg.
Breast Care (Basel), 2016 Dec 07; 11(5). PMID: 27920623    Free PMC article.
BRCAness as a Biomarker for Predicting Prognosis and Response to Anthracycline-Based Adjuvant Chemotherapy for Patients with Triple-Negative Breast Cancer.
Hitomi Mori, Makoto Kubo, +11 authors, Masafumi Nakamura.
PLoS One, 2016 Dec 16; 11(12). PMID: 27977696    Free PMC article.
Triple Negative Breast Cancer: Nanosolutions for a Big Challenge.
Tânia Filipa S Mendes, Leon D Kluskens, Lígia Raquel Rodrigues.
Adv Sci (Weinh), 2015 Jul 17; 2(11). PMID: 27980912    Free PMC article.
Risk factors of locoregional relapse in locally advanced breast cancer treated with neoadjuvant chemotherapy following mastectomy and radiotherapy.
Liang Huang, Sheng Chen, Wentao T Yang, Zhiming Shao.
Oncotarget, 2017 Jan 06; 8(24). PMID: 28055977    Free PMC article.
Prognostic significance of Ki67 in Chinese women diagnosed with ER+/HER2- breast cancers by the 2015 St. Gallen consensus classification.
Yue Hu, Ran Gu, +9 authors, Weijuan Jia.
BMC Cancer, 2017 Jan 08; 17(1). PMID: 28061893    Free PMC article.
The combination of PD-L1 expression and decreased tumor-infiltrating lymphocytes is associated with a poor prognosis in triple-negative breast cancer.
Hitomi Mori, Makoto Kubo, +10 authors, Masafumi Nakamura.
Oncotarget, 2017 Jan 21; 8(9). PMID: 28107186    Free PMC article.
A cohort study of ethnic differences in use of adjuvant chemotherapy and radiation therapy for breast cancer in New Zealand.
Sanjeewa Seneviratne, Ian Campbell, Nina Scott, Ross Lawrenson.
BMC Health Serv Res, 2017 Jan 23; 17(1). PMID: 28109301    Free PMC article.
Dasatinib inhibits c-src phosphorylation and prevents the proliferation of Triple-Negative Breast Cancer (TNBC) cells which overexpress Syndecan-Binding Protein (SDCBP).
Xiao-Long Qian, Jun Zhang, +7 authors, Li Fu.
PLoS One, 2017 Feb 01; 12(1). PMID: 28141839    Free PMC article.
Ki-67 as a prognostic marker according to breast cancer molecular subtype.
Nahed A Soliman, Shaimaa M Yussif.
Cancer Biol Med, 2017 Feb 06; 13(4). PMID: 28154782    Free PMC article.
Polymorphisms of ESR1, UGT1A1, HCN1, MAP3K1 and CYP2B6 are associated with the prognosis of hormone receptor-positive early breast cancer.
Sung-Hsin Kuo, Shi-Yi Yang, +4 authors, Chiun-Sheng Huang.
Oncotarget, 2017 Feb 09; 8(13). PMID: 28178648    Free PMC article.
Opportunities for improving triple-negative breast cancer outcomes: results of a population-based study.
Elisabetta Rapiti, Kim Pinaud, +5 authors, Christine Bouchardy.
Cancer Med, 2017 Feb 18; 6(3). PMID: 28211614    Free PMC article.
Adjuvant treatment recommendations for patients with ER-positive/HER2-negative early breast cancer by Swiss tumor boards using the 21-gene recurrence score (SAKK 26/10).
Bernhard C Pestalozzi, Christoph Tausch, +17 authors, Swiss Group for Clinical Cancer Research (SAKK).
BMC Cancer, 2017 Apr 15; 17(1). PMID: 28407750    Free PMC article.
Management of Aromatase Inhibitor-Associated Bone Loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: Joint position statement of the IOF, CABS, ECTS, IEG, ESCEO IMS, and SIOG.
Peyman Hadji, Matti S Aapro, +18 authors, Robert E Coleman.
J Bone Oncol, 2017 Apr 18; 7. PMID: 28413771    Free PMC article.
Highly Cited. Review.
Indocyanine green detects sentinel lymph nodes in early breast cancer.
Jun Liu, Linping Huang, Ning Wang, Ping Chen.
J Int Med Res, 2017 Apr 19; 45(2). PMID: 28415938    Free PMC article.
Ki67 expression in invasive breast cancer: the use of tissue microarrays compared with whole tissue sections.
Abir A Muftah, Mohammed A Aleskandarany, +7 authors, Andrew R Green.
Breast Cancer Res Treat, 2017 May 10; 164(2). PMID: 28478613    Free PMC article.
Targeting Intracellular Calcium Signaling ([Ca2+]i) to Overcome Acquired Multidrug Resistance of Cancer Cells: A Mini-Overview.
Dietrich Büsselberg, Ana-Maria Florea.
Cancers (Basel), 2017 May 10; 9(5). PMID: 28486397    Free PMC article.
Review.
Novel therapeutic strategies in the treatment of triple-negative breast cancer.
Karima Oualla, Heba M El-Zawahry, +7 authors, Tamer M Fouad.
Ther Adv Med Oncol, 2017 Jul 19; 9(7). PMID: 28717401    Free PMC article.
Review.
Predicting Triple-Negative Breast Cancer Subtype Using Multiple Single Nucleotide Polymorphisms for Breast Cancer Risk and Several Variable Selection Methods.
Lothar Häberle, Alexander Hein, +11 authors, Marius Wunderle.
Geburtshilfe Frauenheilkd, 2017 Aug 02; 77(6). PMID: 28757654    Free PMC article.
Risk Factors for a False-Negative Result of Sentinel Node Biopsy in Patients with Clinically Node-Negative Breast Cancer.
Seung Ah Lee, Hak Min Lee, +5 authors, Seung Il Kim.
Cancer Res Treat, 2017 Aug 02; 50(3). PMID: 28759990    Free PMC article.
Separase is a marker for prognosis and mitotic activity in breast cancer.
Natalia Gurvits, Eliisa Löyttyniemi, +3 authors, Kati Talvinen.
Br J Cancer, 2017 Sep 01; 117(9). PMID: 28859055    Free PMC article.
Predictive factors of pathologic complete response in HER2-positive and axillary lymph node positive breast cancer after neoadjuvant paclitaxel, carboplatin plus with trastuzumab.
Jinhua Ding, Yinlong Yang, +2 authors, Zhiming Shao.
Oncotarget, 2017 Sep 17; 8(34). PMID: 28915617    Free PMC article.
Revisiting the definition of estrogen receptor positivity in HER2-negative primary breast cancer.
T Fujii, T Kogawa, +10 authors, N T Ueno.
Ann Oncol, 2017 Sep 30; 28(10). PMID: 28961844    Free PMC article.
Canine invasive mammary carcinomas as models of human breast cancer. Part 2: immunophenotypes and prognostic significance.
Jérôme Abadie, Frédérique Nguyen, +8 authors, Mario Campone.
Breast Cancer Res Treat, 2017 Oct 25; 167(2). PMID: 29063312    Free PMC article.
Comparison of quality of life between 2-year and 3-or-more-year administration of leuprorelin acetate every-3-months depot in combination with tamoxifen as adjuvant endocrine treatment in premenopausal patients with endocrine-responsive breast cancer: a randomized controlled trial.
Yasuo Ohashi, Eiichi Shiba, +5 authors, Tsukasa Fujimoto.
Support Care Cancer, 2017 Oct 25; 26(3). PMID: 29063390    Free PMC article.
Persistent homology index as a robust quantitative measure of immunohistochemical scoring.
Akihiro Takiyama, Takashi Teramoto, +2 authors, Shinya Tanaka.
Sci Rep, 2017 Oct 27; 7(1). PMID: 29070862    Free PMC article.
Impact of Her-2 Overexpression on Survival of Patients with Metastatic Breast Cancer
Giovana Tavares dos Santos, Natália Dressler Camillo, +6 authors, Claudia Giuliano Bica.
Asian Pac J Cancer Prev, 2017 Oct 27; 18(10). PMID: 29072390    Free PMC article.
PTTG1-interacting protein (PTTG1IP/PBF) predicts breast cancer survival.
Heli Repo, Natalia Gurvits, +8 authors, Pauliina Kronqvist.
BMC Cancer, 2017 Oct 29; 17(1). PMID: 29078751    Free PMC article.
Identifying accessible prognostic factors for breast cancer relapse: a case-study on 405 histologically confirmed node-negative patients.
Ines Zemni, Montassar Ghalleb, +5 authors, Khaled Rahal.
World J Surg Oncol, 2017 Nov 25; 15(1). PMID: 29169398    Free PMC article.
Genes with mutation significance were highly associated with the clinical pattern of patients with breast cancer.
Wan-Jun Ding, Tao Zeng, +3 authors, Zhi Wang.
Oncotarget, 2017 Dec 13; 8(58). PMID: 29228676    Free PMC article.
Prognostic value of tumor-stroma ratio combined with the immune status of tumors in invasive breast carcinoma.
K M H Vangangelt, G W van Pelt, +6 authors, W E Mesker.
Breast Cancer Res Treat, 2017 Dec 24; 168(3). PMID: 29273955    Free PMC article.
Male occult breast cancer with axillary lymph node metastasis as the first manifestation: A case report and literature review.
Ruixin Xu, Jianbin Li, +2 authors, Youzhe Zhu.
Medicine (Baltimore), 2018 Feb 03; 96(51). PMID: 29390502    Free PMC article.
Review.
Independent prognostic impact of preoperative serum carcinoembryonic antigen and cancer antigen 15-3 levels for early breast cancer subtypes.
Michiko Imamura, Takashi Morimoto, +13 authors, Yasuo Miyoshi.
World J Surg Oncol, 2018 Feb 13; 16(1). PMID: 29433529    Free PMC article.
Randomized phase II study of anastrozole plus tegafur-uracil as neoadjuvant therapy for ER-positive breast cancer in postmenopausal Japanese women (Neo-ACET BC).
Takahiro Nakayama, Yasuaki Sagara, +8 authors, Shinzaburo Noguchi.
Cancer Chemother Pharmacol, 2018 Feb 23; 81(4). PMID: 29468454    Free PMC article.
Prognostic & predictive factors for planning adjuvant chemotherapy of early-stage breast cancer.
Onur Esbah, Berna Oksuzoglu.
Indian J Med Res, 2018 Mar 08; 146(5). PMID: 29512598    Free PMC article.
Review.
Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling.
Pernilla Roswall, Matteo Bocci, +24 authors, Kristian Pietras.
Nat Med, 2018 Mar 13; 24(4). PMID: 29529015    Free PMC article.
Highly Cited.
Coexisting genomic aberrations associated with lymph node metastasis in breast cancer.
Li Bao, Zhaoyang Qian, +8 authors, Henrik J Ditzel.
J Clin Invest, 2018 Mar 21; 128(6). PMID: 29558370    Free PMC article.
Analysis of membranous Ki-67 staining in breast cancer and surrounding breast epithelium.
Gábor Cserni.
Virchows Arch, 2018 Mar 30; 473(2). PMID: 29594352
microRNA-10b expression and its correlation with molecular subtypes of early invasive ductal carcinoma.
Chenming Guo, Minggang Fu, +2 authors, Liying Guo.
Exp Ther Med, 2018 Mar 31; 15(3). PMID: 29599829    Free PMC article.
Practical consensus recommendations regarding the management of sentinel lymph node issues in early breast cancer.
Vedant Kabra, R Aggarwal, +9 authors, S Aggarwal.
South Asian J Cancer, 2018 May 04; 7(2). PMID: 29721480    Free PMC article.
Conventional Pathology Versus Gene Signatures for Assessing Luminal A and B Type Breast Cancers: Results of a Prospective Cohort Study.
Julia E C van Steenhoven, Anne Kuijer, +12 authors, Thijs van Dalen.
Genes (Basel), 2018 May 19; 9(5). PMID: 29772837    Free PMC article.
Upregulation of miR-374a promotes tumor metastasis and progression by downregulating LACTB and predicts unfavorable prognosis in breast cancer.
Jun Zhang, Yuting He, +9 authors, Ranran Sun.
Cancer Med, 2018 May 24;. PMID: 29790671    Free PMC article.
Decreased survival in patients with carcinoma of axillary tail versus upper outer quadrant breast cancers: a SEER population-based study.
Zong-Chao Gou, Xi-Yu Liu, +3 authors, Zhi-Ming Shao.
Cancer Manag Res, 2018 May 26; 10. PMID: 29795985    Free PMC article.
Genome-wide multi-omics profiling of the 8p11-p12 amplicon in breast carcinoma.
Toshima Z Parris, Elisabeth Werner Rönnerman, +8 authors, Khalil Helou.
Oncotarget, 2018 May 31; 9(35). PMID: 29844878    Free PMC article.
A Novel Bimodal Imaging Agent Targeting HER2 Molecule of Breast Cancer.
Wei Lv, Yamei Shen, +6 authors, Li Zhang.
J Immunol Res, 2018 Jun 02; 2018. PMID: 29854844    Free PMC article.
Relationship Between ADAMTS8, ADAMTS18, and ADAMTS20 (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) Expressions and Tumor Molecular Classification, Clinical Pathological Parameters, and Prognosis in Breast Invasive Ductal Carcinoma.
Xuhui Guo, Juntao Li, +3 authors, Xudong Wei.
Med Sci Monit, 2018 Jun 04; 24. PMID: 29860265    Free PMC article.
Application of Real-time Elastography Ultrasound in the Diagnosis of Axillary Lymph Node Metastasis in Breast Cancer Patients.
Yanjun Xu, Xiaojun Bai, +4 authors, Li Yu.
Sci Rep, 2018 Jul 08; 8(1). PMID: 29980694    Free PMC article.
Using Probability for Pathological Complete Response (pCR) as a Decision Support Marker for Neoadjuvant Chemotherapy in HER2 Negative Breast Cancer Patients - a Survey Among Physicians.
Paul Gass, Michael Untch, +18 authors, Naiba Nabieva.
Geburtshilfe Frauenheilkd, 2018 Jul 31; 78(7). PMID: 30057427    Free PMC article.
Formin Proteins FHOD1 and INF2 in Triple-Negative Breast Cancer: Association With Basal Markers and Functional Activities.
Vanina D Heuser, Naziha Mansuri, +5 authors, Maria Gardberg.
Breast Cancer (Auckl), 2018 Aug 31; 12. PMID: 30158824    Free PMC article.
Identification of Key Genes and Pathways in Triple-Negative Breast Cancer by Integrated Bioinformatics Analysis.
Pengzhi Dong, Bing Yu, +2 authors, Fangfang Liu.
Biomed Res Int, 2018 Sep 04; 2018. PMID: 30175120    Free PMC article.
Lymph node metastasis and high serum CEA are important prognostic factors in hormone receptor positive and HER2 negative breast cancer.
Yoshimasa Kosaka, Naoko Minatani, +10 authors, Masahiko Watanabe.
Mol Clin Oncol, 2018 Nov 08; 9(5). PMID: 30402236    Free PMC article.
Tumor-infiltrating lymphocytes and CD8+ T cells predict survival of triple-negative breast cancer.
H Vihervuori, T A Autere, +5 authors, P Kronqvist.
J Cancer Res Clin Oncol, 2019 Sep 29; 145(12). PMID: 31562550    Free PMC article.
Endocrine-responsive lobular carcinoma of the breast: features associated with risk of late distant recurrence.
Fabio Conforti, Laura Pala, +12 authors, Aron Goldhirsch.
Breast Cancer Res, 2020 Jan 01; 21(1). PMID: 31888717    Free PMC article.
BOne HEalth ManagEment in Patients with Early Breast Cancer: A Retrospective Italian Osteoncology Center "Real-Life" Experience (BOHEME Study).
Federica Recine, Alberto Bongiovanni, +14 authors, Toni Ibrahim.
J Clin Med, 2019 Nov 09; 8(11). PMID: 31698876    Free PMC article.
MicroRNA-137 Inhibits Cancer Progression by Targeting Del-1 in Triple-Negative Breast Cancer Cells.
Soo Jung Lee, Jae-Hwan Jeong, +6 authors, Yee Soo Chae.
Int J Mol Sci, 2019 Dec 11; 20(24). PMID: 31817673    Free PMC article.
The Prognostic Impact of Hormonal Receptor and HER-2 Expression Discordance in Metastatic Breast Cancer Patients.
Ziyan Yang, Nani Li, +2 authors, Xiaojia Wang.
Onco Targets Ther, 2020 Feb 27; 13. PMID: 32099389    Free PMC article.
21-Gene Recurrence Score and Adjuvant Chemotherapy Decision for Breast Cancer Patients with Positive Lymph Nodes.
Yiwei Tong, Jiayi Wu, +6 authors, Kunwei Shen.
Sci Rep, 2019 Sep 13; 9(1). PMID: 31511599    Free PMC article.
Practical approaches to automated digital image analysis of Ki-67 labeling index in 997 breast carcinomas and causes of discordance with visual assessment.
Ah-Young Kwon, Ha Young Park, +7 authors, Eun Yoon Cho.
PLoS One, 2019 Feb 21; 14(2). PMID: 30785924    Free PMC article.
Sentinel lymph node biopsy in microinvasive ductal carcinoma in situ.
F Magnoni, G Massari, +6 authors, V S Sacchini.
Br J Surg, 2019 Feb 23; 106(4). PMID: 30791092    Free PMC article.
Developing an Indonesian fertility preservation questionnaire for health care providers treating patients with cancer: A preliminary pilot study.
Achmad Kemal Harzif, Raymond Surya, +3 authors, Budi Wiweko.
F1000Res, 2019 Jul 10; 7. PMID: 31275556    Free PMC article.
Do 21-Gene Recurrence Score Influence Chemotherapy Decisions in T1bN0 Breast Cancer Patients?
Jing Yu, Jiayi Wu, +6 authors, Kunwei Shen.
Front Oncol, 2020 Jun 02; 10. PMID: 32477946    Free PMC article.
Metastatic disease in head & neck oncology.
Paolo Pisani, Mario Airoldi, +34 authors, Angelo Zigliani.
Acta Otorhinolaryngol Ital, 2020 May 30; 40(SUPPL. 1). PMID: 32469009    Free PMC article.
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A prognostic model based on cell-cycle control predicts outcome of breast cancer patients.
Heli Repo, Eliisa Löyttyniemi, +4 authors, Pauliina Kronqvist.
BMC Cancer, 2020 Jun 18; 20(1). PMID: 32546141    Free PMC article.
Superior breast cancer metastasis risk stratification using an epithelial-mesenchymal-amoeboid transition gene signature.
Amin Emad, Tania Ray, +4 authors, Partha S Ray.
Breast Cancer Res, 2020 Jul 10; 22(1). PMID: 32641077    Free PMC article.
Re-evaluation of HER2 status in 606 breast cancers-gene protein assay on tissue microarrays versus routine pathological assessment.
Emma Sandén, Somayeh Khazaei, +4 authors, Helena Jernström.
Virchows Arch, 2020 Feb 23; 477(2). PMID: 32080761    Free PMC article.
Is There a Role for Post-Mastectomy Radiotherapy for T1-2N1 Breast Cancers With Node-Positive Pathology After Patients Become Node-Negative Pathology Following Neoadjuvant Chemotherapy?
Qian Wang, Jingjing Zhao, +9 authors, Bing Sun.
Front Oncol, 2020 Jul 23; 10. PMID: 32695661    Free PMC article.
Risk stratification in luminal-type breast cancer: Comparison of Ki-67 with EndoPredict test results.
Aurelia Noske, Sophie-Isabelle Anders, +6 authors, Evelyn Klein.
Breast, 2019 Dec 02; 49. PMID: 31786414    Free PMC article.
Primary 21-Gene Recurrence Score and Disease Outcome in Loco-Regional and Distant Recurrent Breast Cancer Patients.
Yujie Lu, Yiwei Tong, +10 authors, Kunwei Shen.
Front Oncol, 2020 Aug 28; 10. PMID: 32850415    Free PMC article.
Association of sonographic features and molecular subtypes in predicting breast cancer disease outcomes.
Haoyu Wang, Jiejie Yao, +3 authors, Kunwei Shen.
Cancer Med, 2020 Jul 14; 9(17). PMID: 32657039    Free PMC article.
Circulating MicroRNAs and Blood-Brain-Barrier Function in Breast Cancer Metastasis.
Carolin J Curtaz, Constanze Schmitt, +3 authors, Malgorzata Burek.
Curr Pharm Des, 2020 Mar 17; 26(13). PMID: 32175838    Free PMC article.
Emerging Opportunities of Radiotherapy Combined With Immunotherapy in the Era of Breast Cancer Heterogeneity.
Pelagia G Tsoutsou, Khalil Zaman, +3 authors, Marie-Catherine Vozenin.
Front Oncol, 2019 Jan 09; 8. PMID: 30619749    Free PMC article.
Review.
SP1 and STAT3 Functionally Synergize to Induce the RhoU Small GTPase and a Subclass of Non-canonical WNT Responsive Genes Correlating with Poor Prognosis in Breast Cancer.
Emanuele Monteleone, Valeria Orecchia, +7 authors, Valeria Poli.
Cancers (Basel), 2019 Jan 19; 11(1). PMID: 30654518    Free PMC article.
Improved prognosis of low baseline neutrophil-to-lymphocyte ratio is significantly exclusive in breast cancer patients with high absolute counts of lymphocytes.
Yukie Fujimoto, Hiromi Ozawa, +4 authors, Yasuo Miyoshi.
Mol Clin Oncol, 2019 Jan 27; 10(2). PMID: 30680208    Free PMC article.
Integrated Multiparametric Radiomics and Informatics System for Characterizing Breast Tumor Characteristics with the OncotypeDX Gene Assay.
Michael A Jacobs, Christopher B Umbricht, +5 authors, Antonio C Wolff.
Cancers (Basel), 2020 Oct 01; 12(10). PMID: 32992569    Free PMC article.
Diagnostic value of serum HER2 levels in breast cancer: a systematic review and meta-analysis.
Amir Shamshirian, Amir Reza Aref, +7 authors, Reza Alizadeh-Navaei.
BMC Cancer, 2020 Nov 02; 20(1). PMID: 33129287    Free PMC article.
Comparative study of one-step nucleic acid amplification assay, frozen section, and touch imprint cytology for intraoperative assessment of breast sentinel lymph node in Chinese patients.
Yong-sheng Wang, Tao Ou-yang, +8 authors, Ai-ping Lu.
Cancer Sci, 2012 Aug 29; 103(11). PMID: 22924886    Free PMC article.
Axillary Lymph Node Dissection Does Not Improve Post-mastectomy Overall or Disease-Free Survival among Breast Cancer Patients with 1-3 Positive Nodes.
Ji Hyeon Joo, Su Ssan Kim, +7 authors, Beom Seok Ko.
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[Ki67: biological intertumor variance versus variance of assay].
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Pathologe, 2018 Oct 18; 39(Suppl 2). PMID: 30327857
Review.
Immunohistochemical Evaluation of Ki-67 and Comparison with Clinicopathologic Factors in Breast Carcinomas
Nguiessan Alphonse Aman, Brahima Doukoure, +5 authors, Ahoua Benjamin Effi.
Asian Pac J Cancer Prev, 2019 Jan 27; 20(1). PMID: 30678383    Free PMC article.
Specific allelic variants of SNPs in the MDM2 and MDMX genes are associated with earlier tumor onset and progression in Caucasian breast cancer patients.
Marcus Bauer, Eva Johanna Kantelhardt, +15 authors, Martina Vetter.
Oncotarget, 2019 Apr 09; 10(20). PMID: 30956778    Free PMC article.
T-bet+ lymphocytes infiltration as an independent better prognostic indicator for triple-negative breast cancer.
Hitomi Mori, Makoto Kubo, +11 authors, Masafumi Nakamura.
Breast Cancer Res Treat, 2019 May 10; 176(3). PMID: 31069590    Free PMC article.
Clinicopathological Features and Disease Outcome in Breast Cancer Patients with Hormonal Receptor Discordance between Core Needle Biopsy and Following Surgical Sample.
Siji Zhu, Jiayi Wu, +7 authors, Kunwei Shen.
Ann Surg Oncol, 2019 May 31; 26(9). PMID: 31144143    Free PMC article.
Update Breast Cancer 2019 Part 3 - Current Developments in Early Breast Cancer: Review and Critical Assessment by an International Expert Panel.
Hans-Christian Kolberg, Andreas Schneeweiss, +18 authors, Sara Y Brucker.
Geburtshilfe Frauenheilkd, 2019 Jun 01; 79(5). PMID: 31148847    Free PMC article.
Development of a predictive model utilizing the neutrophil to lymphocyte ratio to predict neoadjuvant chemotherapy efficacy in early breast cancer patients.
Jiujun Zhu, Dechuang Jiao, +4 authors, Zhenzhen Liu.
Sci Rep, 2021 Jan 16; 11(1). PMID: 33446717    Free PMC article.
HER2-Positive Breast Cancer Patients with Pre-Treatment Axillary Involvement or Postmenopausal Status Benefit from Neoadjuvant Rather than Adjuvant Chemotherapy Plus Trastuzumab Regimens.
Enora Laas, Arnaud Bresset, +8 authors, Anne-Sophie Hamy.
Cancers (Basel), 2021 Jan 28; 13(3). PMID: 33498405    Free PMC article.