Journal Article
. 2011 Jun; 14(4):429-37.
doi: 10.1016/j.jval.2011.01.011.

Conducting indirect-treatment-comparison and network-meta-analysis studies: report of the ISPOR Task Force on Indirect Treatment Comparisons Good Research Practices: part 2

David C Hoaglin 1 Neil Hawkins  Jeroen P Jansen  David A Scott  Robbin Itzler  Joseph C Cappelleri  Cornelis Boersma  David Thompson  Kay M Larholt  Mireya Diaz  Annabel Barrett  
  • PMID: 21669367
  •     191 citations


Evidence-based health care decision making requires comparison of all relevant competing interventions. In the absence of randomized controlled trials involving a direct comparison of all treatments of interest, indirect treatment comparisons and network meta-analysis provide useful evidence for judiciously selecting the best treatment(s). Mixed treatment comparisons, a special case of network meta-analysis, combine direct evidence and indirect evidence for particular pairwise comparisons, thereby synthesizing a greater share of the available evidence than traditional meta-analysis. This report from the International Society for Pharmacoeconomics and Outcomes Research Indirect Treatment Comparisons Good Research Practices Task Force provides guidance on technical aspects of conducting network meta-analyses (our use of this term includes most methods that involve meta-analysis in the context of a network of evidence). We start with a discussion of strategies for developing networks of evidence. Next we briefly review assumptions of network meta-analysis. Then we focus on the statistical analysis of the data: objectives, models (fixed-effects and random-effects), frequentist versus Bayesian approaches, and model validation. A checklist highlights key components of network meta-analysis, and substantial examples illustrate indirect treatment comparisons (both frequentist and Bayesian approaches) and network meta-analysis. A further section discusses eight key areas for future research.

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The Cost-effectiveness of Dulaglutide 1.5mg versus Exenatide QW for the Treatment of Patients with Type 2 Diabetes Mellitus in France.
Mickael Basson, Dionysios Ntais, +5 authors, Kirsi Norrbacka.
Diabetes Ther, 2017 Nov 15; 9(1). PMID: 29134607    Free PMC article.
Comparative efficacy and safety of antibiotics used to treat acute bacterial skin and skin structure infections: Results of a network meta-analysis.
Julian F Guest, Jaime Esteban, +3 authors, Miquel Serra.
PLoS One, 2017 Nov 15; 12(11). PMID: 29136035    Free PMC article.
The Assessment for Disinvestment of Intramuscular Interferon Beta for Relapsing-Remitting Multiple Sclerosis in Brazil.
Livia Lovato Pires de Lemos, Augusto Afonso Guerra Júnior, +11 authors, Francisco de Assis Acurcio.
Pharmacoeconomics, 2017 Nov 16; 36(2). PMID: 29139001    Free PMC article.
An Indirect Comparison of Changes in the Impact of Weight on Quality of Life Among Subjects with Type 2 Diabetes Treated with Antihyperglycemic Agents in Dual Therapy with Metformin.
Shana B Traina, April Slee, Suzy Van Sanden, Joris Diels.
Diabetes Ther, 2017 Dec 14; 9(1). PMID: 29236222    Free PMC article.
Pharmacological interventions for preventing post-operative atrial fibrillation in patients undergoing cardiac surgery: a network meta-analysis protocol.
Xiaoqin Wang, Liang Yao, +6 authors, Kehu Yang.
BMJ Open, 2018 Jan 01; 7(12). PMID: 29289938    Free PMC article.
A network meta-analysis on the comparative efficacy of different dietary approaches on glycaemic control in patients with type 2 diabetes mellitus.
Lukas Schwingshackl, Anna Chaimani, +2 authors, Heiner Boeing.
Eur J Epidemiol, 2018 Jan 06; 33(2). PMID: 29302846    Free PMC article.
Highly Cited.
Methodological challenges in indirect treatment comparisons: spotlight on a recent comparison of long-acting injectable aripiprazole versus paliperidone palmitate in the treatment of schizophrenia.
Arun Singh, Srihari Gopal, +5 authors, Jesse Berlin.
Int Clin Psychopharmacol, 2018 Mar 02; 33(4). PMID: 29494348    Free PMC article.
Comparison of non-insulin antidiabetic agents as an add-on drug to insulin therapy in type 2 diabetes: a network meta-analysis.
Jeong-Hwa Yoon, Se Hee Min, +2 authors, Seokyung Hahn.
Sci Rep, 2018 Mar 08; 8(1). PMID: 29511288    Free PMC article.
Evaluating optimal utilisation of technology in type 1 diabetes mellitus from a clinical and health economic perspective: protocol for a systematic review.
Anthony Pease, Clement Lo, +2 authors, Sophia Zoungas.
Syst Rev, 2018 Mar 14; 7(1). PMID: 29530081    Free PMC article.
Pharmacological treatments for alleviating agitation in dementia: a systematic review and network meta-analysis.
Khachen Kongpakwattana, Ratree Sawangjit, +3 authors, Nathorn Chaiyakunapruk.
Br J Clin Pharmacol, 2018 Apr 11; 84(7). PMID: 29637593    Free PMC article.
Systematic Review.
A Systematic Literature Review and Network Meta-Analysis Comparing Once-Weekly Semaglutide with Other GLP-1 Receptor Agonists in Patients with Type 2 Diabetes Previously Receiving 1-2 Oral Anti-Diabetic Drugs.
Michal Witkowski, Lars Wilkinson, +3 authors, Hrvoje Vrazic.
Diabetes Ther, 2018 Apr 21; 9(3). PMID: 29675798    Free PMC article.
Mapping the characteristics of network meta-analyses on drug therapy: A systematic review.
Fernanda S Tonin, Laiza M Steimbach, +3 authors, Fernando Fernandez-Llimos.
PLoS One, 2018 May 01; 13(4). PMID: 29709028    Free PMC article.
Systematic Review.
A Systematic Literature Review and Network Meta-Analysis Comparing Once-Weekly Semaglutide with Other GLP-1 Receptor Agonists in Patients with Type 2 Diabetes Previously Receiving Basal Insulin.
Michal Witkowski, Lars Wilkinson, +3 authors, Hrvoje Vrazic.
Diabetes Ther, 2018 May 02; 9(3). PMID: 29713961    Free PMC article.
Network meta-analysis: an introduction for pharmacists.
Yina Xu, Mohamed Amine Amiche, Mina Tadrous.
Int J Clin Pharm, 2018 May 23; 40(5). PMID: 29785685
Network meta-analysis: users' guide for pediatricians.
Reem Al Khalifah, Ivan D Florez, Gordon Guyatt, Lehana Thabane.
BMC Pediatr, 2018 May 31; 18(1). PMID: 29843665    Free PMC article.
No differences in the efficacy among various core decompression modalities and non-operative treatment: a network meta-analysis.
Byung-Ho Yoon, Young-Kyun Lee, +2 authors, Kyung-Hoi Koo.
Int Orthop, 2018 Jun 02; 42(12). PMID: 29855682
Efficacy of Anti-HER2 Agents in Combination With Adjuvant or Neoadjuvant Chemotherapy for Early and Locally Advanced HER2-Positive Breast Cancer Patients: A Network Meta-Analysis.
Márcio Debiasi, Carisi A Polanczyk, +12 authors, Olufunmilayo Olopade.
Front Oncol, 2018 Jun 07; 8. PMID: 29872641    Free PMC article.
History and publication trends in the diffusion and early uptake of indirect comparison meta-analytic methods to study drugs: animated coauthorship networks over time.
Joann K Ban, Mina Tadrous, +2 authors, Suzanne M Cadarette.
BMJ Open, 2018 Jul 02; 8(6). PMID: 29961001    Free PMC article.
Disease-Modifying Therapies for Relapsing-Remitting Multiple Sclerosis: A Network Meta-Analysis.
Rosa C Lucchetta, Fernanda S Tonin, +8 authors, Astrid Wiens.
CNS Drugs, 2018 Jul 18; 32(9). PMID: 30014314
Systematic Review.
The efficacy and safety of first-line therapies for preventing chronic post-surgical pain: a network meta-analysis.
Jie Ning, Jing Luo, +8 authors, Rongzhong Huang.
Oncotarget, 2018 Sep 04; 9(62). PMID: 30174798    Free PMC article.
Efficacy and safety of chemopreventive agents on colorectal cancer incidence and mortality: systematic review and network meta-analysis.
Sajesh K Veettil, Peerawat Jinatongthai, +7 authors, Nathorn Chaiyakunapruk.
Clin Epidemiol, 2018 Oct 24; 10. PMID: 30349391    Free PMC article.
Efficacy, effectiveness, and safety of herpes zoster vaccines in adults aged 50 and older: systematic review and network meta-analysis.
Andrea C Tricco, Wasifa Zarin, +8 authors, Sharon E Straus.
BMJ, 2018 Oct 27; 363. PMID: 30361202    Free PMC article.
Systematic Review.
Partially systematic thoughts on the history of systematic reviews.
Mike Clarke.
Syst Rev, 2018 Oct 29; 7(1). PMID: 30368251    Free PMC article.
Optimal use of tranexamic acid for total hip arthroplasty: A network meta-analysis.
Byung-Ho Yoon, Tae-Young Kim, +3 authors, Kyung-Hoi Koo.
PLoS One, 2018 Nov 01; 13(10). PMID: 30379905    Free PMC article.
Which treatment is most effective for patients with patellofemoral pain? A protocol for a living systematic review including network meta-analysis.
Marinus Winters, Sinead Holden, +5 authors, Michael Skovdal Rathleff.
BMJ Open, 2018 Nov 21; 8(11). PMID: 30455387    Free PMC article.
Systematic Review.
Indirect Treatment Comparison of the Efficacy and Safety of Sarilumab Monotherapy in Rheumatoid Arthritis Patients with Inadequate Response to Conventional Disease-Modifying Antirheumatic Drugs.
Ernest Choy, Nick Freemantle, +7 authors, Thi-Minh-Thao Huynh.
Adv Ther, 2019 Mar 14; 36(4). PMID: 30864105    Free PMC article.
Systematic Review.
Comparative assessment of budesonide-MMX and mesalamine in active, mild-to-moderate ulcerative colitis: A systematic review and network meta-analysis.
Stefanos Bonovas, Georgios K Nikolopoulos, +5 authors, Silvio Danese.
Br J Clin Pharmacol, 2019 Jul 04; 85(10). PMID: 31269287    Free PMC article.
Systematic Review.
Synbiotics for prevention of ventilator-associated pneumonia: a probiotics strain-specific network meta-analysis.
Qiong-Li Fan, Xiu-Mei Yu, +3 authors, Yu-Ping Zhang.
J Int Med Res, 2019 Oct 04; 47(11). PMID: 31578896    Free PMC article.
Orally Administered Semaglutide Versus GLP-1 RAs in Patients with Type 2 Diabetes Previously Receiving 1-2 Oral Antidiabetics: Systematic Review and Network Meta-Analysis.
Solomon Nuhoho, Jatin Gupta, +3 authors, Abby Paine.
Diabetes Ther, 2019 Oct 11; 10(6). PMID: 31599391    Free PMC article.
Using Matching-Adjusted Indirect Comparisons and Network Meta-analyses to Compare Efficacy of Brexanolone Injection with Selective Serotonin Reuptake Inhibitors for Treating Postpartum Depression.
Miranda C Cooper, Hannah S Kilvert, +2 authors, Adi Eldar-Lissai.
CNS Drugs, 2019 Oct 24; 33(10). PMID: 31642037    Free PMC article.
Cost-Effectiveness Analysis of Vedolizumab Compared with Other Biologics in Anti-TNF-Naïve Patients with Moderate-to-Severe Ulcerative Colitis in Japan.
Luis Hernandez, Hiroyo Kuwabara, +5 authors, Ryuichi Iwakiri.
Pharmacoeconomics, 2019 Sep 26; 38(1). PMID: 31552601    Free PMC article.
Shared parameter model for competing risks and different data summaries in meta-analysis: Implications for common and rare outcomes.
Howard Thom, José A López-López, Nicky J Welton.
Res Synth Methods, 2019 Jul 23; 11(1). PMID: 31330089    Free PMC article.
Rapid Response of Biologic Treatments of Moderate-to-Severe Plaque Psoriasis: A Comprehensive Investigation Using Bayesian and Frequentist Network Meta-analyses.
Richard B Warren, Kyoungah See, +5 authors, Alexander Egeberg.
Dermatol Ther (Heidelb), 2019 Nov 07; 10(1). PMID: 31686337    Free PMC article.
Tofacitinib for the treatment of moderately to severely active ulcerative colitis: a systematic review, network meta-analysis and economic evaluation.
Christoph Lohan, Alex Diamantopoulos, +3 authors, Laura Marie Sawyer.
BMJ Open Gastroenterol, 2019 Aug 16; 6(1). PMID: 31413856    Free PMC article.
Effect of AcrySof versus other intraocular lens properties on the risk of Nd:YAG capsulotomy after cataract surgery: A systematic literature review and network meta-analysis.
Howard Thom, Frank Ender, +5 authors, Derek O'Boyle.
PLoS One, 2019 Aug 20; 14(8). PMID: 31425548    Free PMC article.
Systematic Review.
Use of Intermediate Endpoints in the Economic Evaluation of New Treatments for Advanced Cancer and Methods Adopted When Suitable Overall Survival Data are Not Available.
Catherine Beauchemin, Marie-Ève Lapierre, +2 authors, Jean Lachaine.
Pharmacoeconomics, 2016 Mar 24; 34(9). PMID: 27002517
Systematic Review.
Comparative effectiveness of biologics for the management of rheumatoid arthritis: systematic review and network meta-analysis.
Rafael Alfonso-Cristancho, Nigel Armstrong, +4 authors, Jos Kleijnen.
Clin Rheumatol, 2016 Oct 12; 36(1). PMID: 27726046
Systematic Review.
CORR Insights®: Postoperative Thromboprophylaxis With New Oral Anticoagulants is Superior to LMWH in Hip Arthroplasty Surgery: Findings from the Swedish Registry.
Kyung-Hoi Koo.
Clin Orthop Relat Res, 2019 May 29; 477(6). PMID: 31136432    Free PMC article.
Comparative efficacy of various anti-ulcer medications after gastric endoscopic submucosal dissection: a systematic review and network meta-analysis.
Eun Hye Kim, Se Woo Park, +2 authors, Chan Hyuk Park.
Surg Endosc, 2018 Sep 01; 33(4). PMID: 30167955
Systematic Review.
Comparative effectiveness of the different components of care provided in heart failure clinics-protocol for a systematic review and network meta-analysis.
Morgan Slater, Joanna Bielecki, +10 authors, Valeria E Rac.
Syst Rev, 2019 Feb 04; 8(1). PMID: 30711016    Free PMC article.
Personalizing Second-Line Type 2 Diabetes Treatment Selection: Combining Network Meta-analysis, Individualized Risk, and Patient Preferences for Unified Decision Support.
Sung Eun Choi, Seth A Berkowitz, +2 authors, Sanjay Basu.
Med Decis Making, 2019 Feb 16; 39(3). PMID: 30767632    Free PMC article.
Botulinum Toxins Type A (Bont-A) in the Management of Lower Limb Spasticity in Children: A Systematic Literature Review and Bayesian Network Meta-analysis.
Patricia Guyot, Chrysostomos Kalyvas, Carole Mamane, Natalya Danchenko.
J Child Neurol, 2019 Feb 26; 34(7). PMID: 30803305    Free PMC article.
Systematic Review.
Temporal effectiveness of interventions to improve medication adherence: A network meta-analysis.
Elyssa Wiecek, Fernanda S Tonin, +3 authors, Victoria Garcia-Cardenas.
PLoS One, 2019 Mar 13; 14(3). PMID: 30861014    Free PMC article.
Systematic Review.
Evaluation of the efficacy and safety of sarilumab combination therapy in patients with rheumatoid arthritis with inadequate response to conventional disease-modifying antirheumatic drugs or tumour necrosis factor α inhibitors: systematic literature review and network meta-analyses.
Ernest Choy, Nick Freemantle, +7 authors, Thi-Minh-Thao Huynh.
RMD Open, 2019 Mar 20; 5(1). PMID: 30886733    Free PMC article.
Efficacy of pressure ulcer prevention interventions in adult intensive care units: a protocol for a systematic review and network meta-analysis.
Yixiu Du, Fangqin Wu, +5 authors, Yu Zhang.
BMJ Open, 2019 Apr 11; 9(4). PMID: 30967408    Free PMC article.
Comparative Efficacy of Bariatric Surgery in the Treatment of Morbid Obesity and Diabetes Mellitus: a Systematic Review and Network Meta-Analysis.
Chan Hyuk Park, Seung-Joo Nam, +9 authors, Korean Research Group for Endoscopic Management of Metabolic Disorder and Obesity.
Obes Surg, 2019 May 01; 29(7). PMID: 31037599
Systematic Review.
Comparative Efficacy and Safety of Dupilumab and Benralizumab in Patients with Inadequately Controlled Asthma: A Systematic Review.
Koichi Ando, Akihiko Tanaka, Hironori Sagara.
Int J Mol Sci, 2020 Feb 06; 21(3). PMID: 32019141    Free PMC article.
Systematic Review.
A systematic review and network meta-analysis of adjuvant therapy for curatively resected biliary tract cancers.
M Kish, K Chan, K Perry, Y J Ko.
Curr Oncol, 2020 Mar 29; 27(1). PMID: 32218664    Free PMC article.
Systematic Review.
Siyaphambili protocol: An evaluation of randomized, nurse-led adaptive HIV treatment interventions for cisgender female sex workers living with HIV in Durban, South Africa.
Carly A Comins, Sheree R Schwartz, +11 authors, Stefan Baral.
Res Nurs Health, 2019 Jan 16; 42(2). PMID: 30644999    Free PMC article.
CINeMA: An approach for assessing confidence in the results of a network meta-analysis.
Adriani Nikolakopoulou, Julian P T Higgins, +4 authors, Georgia Salanti.
PLoS Med, 2020 Apr 04; 17(4). PMID: 32243458    Free PMC article.
Bayesian Network Meta-analysis of Multiple Outcomes in Dental Research.
Menglu Liang, Qinshu Lian, +3 authors, Haitao Chu.
J Evid Based Dent Pract, 2020 May 10; 20(1). PMID: 32381410    Free PMC article.
Brigatinib and Alectinib for ALK Rearrangement-Positive Advanced Non-Small Cell Lung Cancer With or Without Central Nervous System Metastasis: A Systematic Review and Network Meta-Analysis.
Koichi Ando, Kaho Akimoto, +8 authors, Hironori Sagara.
Cancers (Basel), 2020 Apr 16; 12(4). PMID: 32290309    Free PMC article.
A Network Meta-Analysis of Surgical Treatment in Patients With Early Breast Cancer.
Yu Gui, Xunzhou Liu, +5 authors, Li Chen.
J Natl Cancer Inst, 2019 Jun 13; 111(9). PMID: 31187142    Free PMC article.
Estimating Transition Probabilities from Published Evidence: A Tutorial for Decision Modelers.
Risha Gidwani, Louise B Russell.
Pharmacoeconomics, 2020 Aug 17; 38(11). PMID: 32797380    Free PMC article.
Nivolumab plus Ipilimumab versus Existing Immunotherapies in Patients with PD-L1-Positive Advanced Non-Small Cell Lung Cancer: A Systematic Review and Network Meta-Analysis.
Koichi Ando, Yasunari Kishino, +6 authors, Hironori Sagara.
Cancers (Basel), 2020 Jul 19; 12(7). PMID: 32679702    Free PMC article.
Ertugliflozin Compared to Other Anti-hyperglycemic Agents as Monotherapy and Add-on Therapy in Type 2 Diabetes: A Systematic Literature Review and Network Meta-Analysis.
Ann M McNeill, Glenn Davies, +6 authors, Euan McLeod.
Diabetes Ther, 2019 Jan 29; 10(2). PMID: 30689140    Free PMC article.
Neoadjuvant chemoradiation for locally advanced rectal cancer: a systematic review of the literature with network meta-analysis.
Min Chen, Liang-Zhou Chen, +2 authors, Xue Song.
Cancer Manag Res, 2019 Jan 31; 11. PMID: 30697067    Free PMC article.
Treating Patients with Type 2 Diabetes Mellitus Uncontrolled on Basal Insulin in the Czech Republic: Cost-Effectiveness of IDegLira Versus iGlarLixi.
Johannes Pöhlmann, Monika Russel-Szymczyk, +2 authors, Barnaby Hunt.
Diabetes Ther, 2019 Feb 02; 10(2). PMID: 30706364    Free PMC article.
Efficacy of complementary and integrative medicine on health-related quality of life in cancer patients: a systematic review and meta-analysis.
Wan-Fu Lin, Mao-Feng Zhong, +5 authors, Chang-Quan Ling.
Cancer Manag Res, 2019 Aug 16; 11. PMID: 31413628    Free PMC article.
Crizanlizumab and comparators for adults with sickle cell disease: a systematic review and network meta-analysis.
Howard Thom, Jeroen Jansen, +5 authors, Nirmish Shah.
BMJ Open, 2020 Sep 20; 10(9). PMID: 32948541    Free PMC article.
Systematic Review.
Efficacy of Once-Weekly Semaglutide vs Empagliflozin Added to Metformin in Type 2 Diabetes: Patient-Level Meta-analysis.
Ildiko Lingvay, Matthew S Capehorn, +5 authors, Abby Paine.
J Clin Endocrinol Metab, 2020 Aug 23; 105(12). PMID: 32827435    Free PMC article.
Risk of malignancies in patients with spondyloarthritis treated with biologics compared with those treated with non-biologics: a systematic review and meta-analysis.
Yu Heng Kwan, Ka Keat Lim, +10 authors, Truls Østbye.
Ther Adv Musculoskelet Dis, 2020 Nov 06; 12. PMID: 33149771    Free PMC article.
Overview of Differences and Similarities of Published Mixed Treatment Comparisons on Pharmaceutical Interventions for Multiple Sclerosis.
Maria Pia Sormani, Robert Wolff, +6 authors, Jos Kleijnen.
Neurol Ther, 2020 Sep 27; 9(2). PMID: 32978726    Free PMC article.
A Systematic Review and Mixed Treatment Comparison of Pharmaceutical Interventions for Multiple Sclerosis.
Gavin Giovannoni, Shona Lang, +6 authors, Jos Kleijnen.
Neurol Ther, 2020 Sep 30; 9(2). PMID: 32989721    Free PMC article.
Long-term efficacy of novel therapies in moderate-to-severe plaque psoriasis: a systematic review and network meta-analysis of PASI response.
L M Sawyer, L Cornic, +3 authors, G B Jemec.
J Eur Acad Dermatol Venereol, 2018 Oct 06; 33(2). PMID: 30289198    Free PMC article.
Systematic Review.
An efficacy comparison of anti-vascular growth factor agents and laser photocoagulation in diabetic macular edema: a network meta-analysis incorporating individual patient-level data.
Dominic Muston, Jean-Francois Korobelnik, +4 authors, Peter K Kaiser.
BMC Ophthalmol, 2018 Dec 29; 18(1). PMID: 30591022    Free PMC article.
Pharmacological and non-pharmacological treatments for irritable bowel syndrome: Protocol for a systematic review and network meta-analysis.
Shenghui Zhou, Xiaoli Liu, +4 authors, Hao Tang.
Medicine (Baltimore), 2019 Jul 28; 98(30). PMID: 31348246    Free PMC article.
Systematic Review.
Comparative effectiveness of different forms of traditional Chinese medicine for treatment of post-stroke depression: Protocol for network meta-analysis of randomized controlled trials.
Huiling Chen, Meidan Zhao, +5 authors, Hongwu Wang.
Medicine (Baltimore), 2019 Jul 28; 98(30). PMID: 31348252    Free PMC article.
Systematic Review.
Antiviral Agents for the Prevention and Treatment of Herpes Simplex Virus Type-1 Infection in Clinical Oncology: A Network Meta-Analysis.
Farah Wasim Aribi Al-Zoobaee, Loo Yee Shen, +3 authors, Rohit Kunnath Menon.
Int J Environ Res Public Health, 2020 Dec 04; 17(23). PMID: 33265920    Free PMC article.
Reading and interpreting reviews for health professionals: a practical review.
Michele Antonelli, Fabio Firenzuoli, +2 authors, Davide Donelli.
Intern Emerg Med, 2020 Apr 14; 15(6). PMID: 32281054
Comparative Efficacy of Dual and Single Initiation of Add-On Oral Antihyperglycemic Agents in Type 2 Diabetes Uncontrolled on Metformin Alone: A Systematic Literature Review and Network Meta-Analysis.
Dominik Lautsch, Adnan Alsumali, +7 authors, Swapnil Rajpathak.
Diabetes Ther, 2020 Dec 15; 12(1). PMID: 33313996    Free PMC article.
Comparative Efficacy and Safety of Anti-PD-1/PD-L1 Immune Checkpoint Inhibitors for Refractory or Relapsed Advanced Non-Small-Cell Lung Cancer-A Systematic Review and Network Meta-Analysis.
Koichi Ando, Ryo Manabe, +6 authors, Hironori Sagara.
Cancers (Basel), 2021 Feb 10; 13(1). PMID: 33561074    Free PMC article.
Network meta-analysis of the treatment efficacy of different lasers for peri-implantitis.
Meng-Long Hu, Gang Zheng, +3 authors, Jian-Min Han.
Lasers Med Sci, 2021 Feb 17; 36(3). PMID: 33590365
Efficacy of biologic therapies for biologic-naïve Japanese patients with moderately to severely active ulcerative colitis: a network meta-analysis.
Toshifumi Hibi, Isao Kamae, +4 authors, Haridarshan Patel.
Intest Res, 2020 Apr 22; 19(1). PMID: 32312035    Free PMC article.
Renal Denervation for Uncontrolled and Resistant Hypertension: Systematic Review and Network Meta-Analysis of Randomized Trials.
Jonathan Silverwatch, Kristen E Marti, +6 authors, Adrian V Hernandez.
J Clin Med, 2021 Mar 07; 10(4). PMID: 33669195    Free PMC article.
Once-Daily Oral Semaglutide Versus Injectable GLP-1 RAs in People with Type 2 Diabetes Inadequately Controlled on Basal Insulin: Systematic Review and Network Meta-analysis.
Barrie Chubb, Palvi Gupta, +3 authors, Michelle Orme.
Diabetes Ther, 2021 Mar 17; 12(5). PMID: 33723769    Free PMC article.
Very-low-dose aspirin and surveillance colonoscopy is cost-effective in secondary prevention of colorectal cancer in individuals with advanced adenomas: network meta-analysis and cost-effectiveness analysis.
Sajesh K Veettil, Siang Tong Kew, +4 authors, Nathorn Chaiyakunapruk.
BMC Gastroenterol, 2021 Mar 22; 21(1). PMID: 33743605    Free PMC article.
Systematic Review.
Comparative Efficacy and Safety of Immunotherapeutic Regimens with PD-1/PD-L1 Inhibitors for Previously Untreated Extensive-Stage Small Cell Lung Cancer: A Systematic Review and Network Meta-Analysis.
Koichi Ando, Ryo Manabe, +6 authors, Hironori Sagara.
Curr Oncol, 2021 Mar 07; 28(2). PMID: 33673470    Free PMC article.
Comparative efficacy of subcutaneous (CT-P13) and intravenous infliximab in adult patients with rheumatoid arthritis: a network meta-regression of individual patient data from two randomised trials.
Bernard Combe, Yannick Allanore, +10 authors, Dae Hyun Yoo.
Arthritis Res Ther, 2021 Apr 18; 23(1). PMID: 33863352    Free PMC article.
Efficacy and tolerability of atypical antipsychotics for acute bipolar depression: a network meta-analysis.
Aditi Kadakia, Carole Dembek, +5 authors, Antony Loebel.
BMC Psychiatry, 2021 May 13; 21(1). PMID: 33975574    Free PMC article.
Systematic Review.
Risk of recurrence among patients with HR-positive, HER2-negative, early breast cancer receiving adjuvant endocrine therapy: A systematic review and meta-analysis.
Elizabeth M Salvo, Abril Oliva Ramirez, +4 authors, Imtiaz A Samjoo.
Breast, 2021 Mar 08; 57. PMID: 33677313    Free PMC article.
Methodological approaches for analysing data from therapeutic efficacy studies.
Solange Whegang Youdom, Leonardo K Basco.
Malar J, 2021 May 23; 20(1). PMID: 34020656    Free PMC article.
Network Meta-Analyses in Inflammatory Bowel Disease.
Siddharth Singh.
Gastroenterol Hepatol (N Y), 2021 May 27; 16(6). PMID: 34035735    Free PMC article.
Comparative Efficacy and Safety of Peficitinib Versus Tofacitinib and Baricitinib for Treatment of Rheumatoid Arthritis: A Systematic Review and Network Meta-Analysis.
Yoshiya Tanaka, Hiroyuki Okumura, +5 authors, Neil M Schultz.
Rheumatol Ther, 2021 Mar 17; 8(2). PMID: 33725321    Free PMC article.
A single-arm trial indirect comparison investigation: a proof-of-concept method to predict venous leg ulcer healing time for a new acellular synthetic matrix matched to standard care control.
Ronald Shannon, Andrea Nelson.
Int Wound J, 2016 Nov 22; 14(4). PMID: 27868341    Free PMC article.
Meta-Decision in Healthcare.
Latifa Mohammad Baynouna Al Ketbi.
Front Public Health, 2021 Jul 03; 9. PMID: 34211958    Free PMC article.
A population-adjusted indirect comparison of cardiovascular benefits of once-weekly subcutaneous semaglutide and dulaglutide in the treatment of patients with type 2 diabetes, with or without established cardiovascular disease.
Lyndon Marc Evans, Linda Mellbin, +3 authors, Anna Sandberg.
Endocrinol Diabetes Metab, 2021 Jul 20; 4(3). PMID: 34277983    Free PMC article.
Management of social isolation and loneliness in community-dwelling older adults: protocol for a network meta-analysis of randomised controlled trials.
Ahreum Lee, Caitlin McArthur, +6 authors, Alexandra Papaioannou.
BMJ Open, 2021 Jul 07; 11(7). PMID: 34226209    Free PMC article.
Comparative Efficacy and Safety of Lorlatinib and Alectinib for ALK-Rearrangement Positive Advanced Non-Small Cell Lung Cancer in Asian and Non-Asian Patients: A Systematic Review and Network Meta-Analysis.
Koichi Ando, Ryo Manabe, +5 authors, Hironori Sagara.
Cancers (Basel), 2021 Aug 08; 13(15). PMID: 34359604    Free PMC article.
Effects of traditional Chinese exercise on patients with cognitive impairment: A systematic review and Bayesian network meta-analysis.
Chen Li, Dongxiang Zheng, Jinglan Luo.
Nurs Open, 2021 Feb 20; 8(5). PMID: 33605528    Free PMC article.
Comparative Efficacy of Antifungal Agents Used in the Treatment of Oropharyngeal Candidiasis among HIV-Infected Adults: A Systematic Review and Network Meta-Analysis.
Shamala Gopal Rajadurai, Mari Kannan Maharajan, Sajesh K Veettil, Divya Gopinath.
J Fungi (Basel), 2021 Aug 27; 7(8). PMID: 34436176    Free PMC article.