Journal Article
. 2011 Sep; 66(2):151-4.
doi: 10.1136/jclinpath-2011-200205.

Evaluation of a completely automated tissue-sectioning machine for paraffin blocks

Maristela L Onozato 1 Stephen Hammond  Mark Merren  Yukako Yagi  
  • PMID: 21900334
  •     12 citations


Tissue-sectioning automation can be a resourceful tool in processing anatomical pathology specimens. The advantages of an automated system compared with traditional manual sectioning are the invariable thickness, uniform orientation and fewer tissue-sectioning artefacts. This short report presents the design of an automated tissue-sectioning device and compares the sectioned specimens with normal manual tissue sectioning performed by an experienced histology technician. The automated system was easy to use, safe and the sectioned material showed acceptable quality with well-preserved morphology and tissue antigenicity. It is expected that the turnaround time will be improved in the near future.

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