Journal Article
. 2011 Oct; 103(22):1656-64.
doi: 10.1093/jnci/djr393.

Assessment of Ki67 in breast cancer: recommendations from the International Ki67 in Breast Cancer working group

Mitch Dowsett 1 Torsten O Nielsen  Roger A'Hern  John Bartlett  R Charles Coombes  Jack Cuzick  Matthew Ellis  N Lynn Henry  Judith C Hugh  Tracy Lively  Lisa McShane  Soon Paik  Frederique Penault-Llorca  Ljudmila Prudkin  Meredith Regan  Janine Salter  Christos Sotiriou  Ian E Smith  Giuseppe Viale  Jo Anne Zujewski  Daniel F Hayes  International Ki-67 in Breast Cancer Working Group  
Affiliations
  • PMID: 21960707
  •     51 References
  •     551 citations

Abstract

Uncontrolled proliferation is a hallmark of cancer. In breast cancer, immunohistochemical assessment of the proportion of cells staining for the nuclear antigen Ki67 has become the most widely used method for comparing proliferation between tumor samples. Potential uses include prognosis, prediction of relative responsiveness or resistance to chemotherapy or endocrine therapy, estimation of residual risk in patients on standard therapy and as a dynamic biomarker of treatment efficacy in samples taken before, during, and after neoadjuvant therapy, particularly neoadjuvant endocrine therapy. Increasingly, Ki67 is measured in these scenarios for clinical research, including as a primary efficacy endpoint for clinical trials, and sometimes for clinical management. At present, the enormous variation in analytical practice markedly limits the value of Ki67 in each of these contexts. On March 12, 2010, an international panel of investigators with substantial expertise in the assessment of Ki67 and in the development of biomarker guidelines was convened in London by the co-chairs of the Breast International Group and North American Breast Cancer Group Biomarker Working Party to consider evidence for potential applications. Comprehensive recommendations on preanalytical and analytical assessment, and interpretation and scoring of Ki67 were formulated based on current evidence. These recommendations are geared toward achieving a harmonized methodology, create greater between-laboratory and between-study comparability, and allow earlier valid applications of this marker in clinical practice.

Ki67 in breast cancer: prognostic and predictive potential.
Rinat Yerushalmi, Ryan Woods, +2 authors, Karen A Gelmon.
Lancet Oncol, 2010 Feb 16; 11(2). PMID: 20152769
Highly Cited. Review.
Relationship between oestrogen receptor status and proliferation in predicting response and long-term outcome to neoadjuvant chemotherapy for breast cancer.
Robin L Jones, Janine Salter, +5 authors, Mitchell Dowsett.
Breast Cancer Res Treat, 2009 Feb 28; 119(2). PMID: 19247830
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer.
M Elizabeth H Hammond, Daniel F Hayes, +29 authors, Antonio C Wolff.
Arch Pathol Lab Med, 2010 Jun 09; 134(6). PMID: 20524868    Free PMC article.
Highly Cited.
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer (unabridged version).
M Elizabeth H Hammond, Daniel F Hayes, +31 authors, College of American Pathologists.
Arch Pathol Lab Med, 2010 Jul 01; 134(7). PMID: 20586616
Highly Cited. Systematic Review.
Comparative validation of the SP6 antibody to Ki67 in breast cancer.
Lila Zabaglo, Janine Salter, +5 authors, Mitch Dowsett.
J Clin Pathol, 2010 Jul 31; 63(9). PMID: 20671052
Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based intrinsic subtype--ACOSOG Z1031.
Matthew J Ellis, Vera J Suman, +17 authors, John A Olson.
J Clin Oncol, 2011 May 11; 29(17). PMID: 21555689    Free PMC article.
Highly Cited.
Quantitative assessment shows loss of antigenic epitopes as a function of pre-analytic variables.
Yalai Bai, Juliana Tolles, +6 authors, Annette M Molinaro.
Lab Invest, 2011 Apr 27; 91(8). PMID: 21519325    Free PMC article.
Which patients benefit most from adjuvant aromatase inhibitors? Results using a composite measure of prognostic risk in the BIG 1-98 randomized trial.
G Viale, M M Regan, +17 authors, BIG 1-98 Collaborative and International Breast Cancer Study Groups.
Ann Oncol, 2011 Feb 22; 22(10). PMID: 21335417    Free PMC article.
Endocrine therapy, new biologicals, and new study designs for presurgical studies in breast cancer.
Mitch Dowsett, Ian Smith, +13 authors, Judith Bliss.
J Natl Cancer Inst Monogr, 2011 Nov 02; 2011(43). PMID: 22043057
Extreme loss of immunoreactive p-Akt and p-Erk1/2 during routine fixation of primary breast cancer.
Isabel F Pinhel, Fiona A Macneill, +7 authors, Mitch Dowsett.
Breast Cancer Res, 2010 Oct 06; 12(5). PMID: 20920193    Free PMC article.
The Ki-67 protein: from the known and the unknown.
T Scholzen, J Gerdes.
J Cell Physiol, 2000 Feb 01; 182(3). PMID: 10653597
Highly Cited. Review.
Validation of tissue microarray technology in breast carcinoma.
R L Camp, L A Charette, D L Rimm.
Lab Invest, 2001 Jan 05; 80(12). PMID: 11140706
Highly Cited.
Effect of raloxifene on breast cancer cell Ki67 and apoptosis: a double-blind, placebo-controlled, randomized clinical trial in postmenopausal patients.
M Dowsett, N J Bundred, +8 authors, D B Muchmore.
Cancer Epidemiol Biomarkers Prev, 2001 Sep 06; 10(9). PMID: 11535548
Comparison of the short-term biological effects of 7alpha-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)-nonyl]estra-1,3,5, (10)-triene-3,17beta-diol (Faslodex) versus tamoxifen in postmenopausal women with primary breast cancer.
J F Robertson, R I Nicholson, +9 authors, M Dixon.
Cancer Res, 2001 Sep 18; 61(18). PMID: 11559545
Effect of prolonged formalin fixation on the immunohistochemical reactivity of breast markers.
Daniel A Arber.
Appl Immunohistochem Mol Morphol, 2002 Jun 08; 10(2). PMID: 12051639
Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial.
M Baum, A U Budzar, +5 authors, ATAC Trialists' Group.
Lancet, 2002 Jul 02; 359(9324). PMID: 12090977
Highly Cited.
Inter-laboratory and inter-observer reproducibility of immunohistochemical assessment of the Ki-67 labelling index in a large multi-centre trial.
Michael Mengel, Reinhard von Wasielewski, +3 authors, Hans Kreipe.
J Pathol, 2002 Oct 11; 198(3). PMID: 12375261
Letrozole inhibits tumor proliferation more effectively than tamoxifen independent of HER1/2 expression status.
Matthew J Ellis, Andrew Coop, +8 authors, William R Miller.
Cancer Res, 2003 Oct 16; 63(19). PMID: 14559846
Studies of the potential utility of Ki67 as a predictive molecular marker of clinical response in primary breast cancer.
L Assersohn, J Salter, +5 authors, M Dowsett.
Breast Cancer Res Treat, 2003 Dec 25; 82(2). PMID: 14692655
Outcome and human epidermal growth factor receptor (HER) 1-4 status in invasive breast carcinomas with proliferation indices evaluated by bromodeoxyuridine labelling.
Sian M Tovey, Caroline J Witton, +3 authors, Timothy G Cooke.
Breast Cancer Res, 2004 Apr 16; 6(3). PMID: 15084248    Free PMC article.
Confidence intervals for the effect of a prognostic factor after selection of an 'optimal' cutpoint.
Norbert Holländer, Willi Sauerbrei, Martin Schumacher.
Stat Med, 2004 May 26; 23(11). PMID: 15160403
Long-term preservation of antigenicity on tissue microarrays.
Kyle A DiVito, Lori A Charette, David L Rimm, Robert L Camp.
Lab Invest, 2004 Jun 15; 84(8). PMID: 15195116
The long-term prognostic significance of the thymidine labelling index in breast cancer.
M Tubiana, M H Pejovic, +2 authors, E P Malaise.
Int J Cancer, 1984 Apr 15; 33(4). PMID: 6706431
Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.
J Gerdes, H Lemke, +3 authors, H Stein.
J Immunol, 1984 Oct 01; 133(4). PMID: 6206131
Highly Cited.
Evaluation of a modeling system for S-phase estimation in breast cancer by flow cytometry.
L G Dressler, L Seamer, +2 authors, W L McGuire.
Cancer Res, 1987 Oct 15; 47(20). PMID: 3652035
Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections.
G Cattoretti, M H Becker, +4 authors, J Gerdes.
J Pathol, 1992 Dec 01; 168(4). PMID: 1484317
Highly Cited.
Effect of fixation time and microwave oven heating time on retrieval of the Ki-67 antigen from paraffin-embedded tissue.
S Munakata, J B Hendricks.
J Histochem Cytochem, 1993 Aug 01; 41(8). PMID: 8331288
The relevance of antibody concentration to the immunohistological quantification of cell proliferation-associated antigens.
D McCormick, C Yu, C Hobbs, P A Hall.
Histopathology, 1993 Jun 01; 22(6). PMID: 8102614
Microwave-antigen retrieval: the importance of pH of the retrieval solution for MIB-1 staining.
M E Boon.
Eur J Morphol, 1996 Dec 01; 34(5). PMID: 9034793
Immunoreactivity to MIB-1 in breast cancer: methodological assessment and comparison with other proliferation indices.
E Benini, S Rao, +2 authors, R Silvestrini.
Cell Prolif, 1997 Mar 01; 30(3-4). PMID: 9375023    Free PMC article.
Oestrogen receptor status, pathological complete response and prognosis in patients receiving neoadjuvant chemotherapy for early breast cancer.
A E Ring, I E Smith, +2 authors, S R Lakhani.
Br J Cancer, 2004 Nov 24; 91(12). PMID: 15558072    Free PMC article.
Short-term changes in Ki-67 during neoadjuvant treatment of primary breast cancer with anastrozole or tamoxifen alone or combined correlate with recurrence-free survival.
Mitch Dowsett, Ian E Smith, +11 authors, IMPACT Trialists.
Clin Cancer Res, 2005 Feb 11; 11(2 Pt 2). PMID: 15701892
Proliferation marker Ki-67 in early breast cancer.
Ander Urruticoechea, Ian E Smith, Mitch Dowsett.
J Clin Oncol, 2005 Sep 30; 23(28). PMID: 16192605
Highly Cited. Review.
A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer.
Breast International Group (BIG) 1-98 Collaborative Group, Beat Thürlimann, +13 authors, Aron Goldhirsch.
N Engl J Med, 2005 Dec 31; 353(26). PMID: 16382061
Highly Cited.
Prognostic value of pathologic complete response after primary chemotherapy in relation to hormone receptor status and other factors.
Valentina Guarneri, Kristine Broglio, +8 authors, Ana M Gonzalez-Angulo.
J Clin Oncol, 2006 Mar 01; 24(7). PMID: 16505422
Highly Cited.
Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer.
Mitch Dowsett, Ian E Smith, +8 authors, IMPACT Trialists Group.
J Natl Cancer Inst, 2007 Jan 18; 99(2). PMID: 17228000
Highly Cited.
The contribution of bifunctional SkipDewax pretreatment solution, rabbit monoclonal antibodies, and polymer detection systems in immunohistochemistry.
Sze Chuen Cesar Wong, John K C Chan, +5 authors, Anthony T C Chan.
Arch Pathol Lab Med, 2007 Jul 10; 131(7). PMID: 17616990
A phase II placebo-controlled trial of neoadjuvant anastrozole alone or with gefitinib in early breast cancer.
Ian E Smith, Geraldine Walsh, +7 authors, Mitch Dowsett.
J Clin Oncol, 2007 Aug 08; 25(25). PMID: 17679728
American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer.
Lyndsay Harris, Herbert Fritsche, +7 authors, American Society of Clinical Oncology.
J Clin Oncol, 2007 Oct 24; 25(33). PMID: 17954709
Highly Cited. Review.
Predictive value of tumor Ki-67 expression in two randomized trials of adjuvant chemoendocrine therapy for node-negative breast cancer.
Giuseppe Viale, Meredith M Regan, +16 authors, International Breast Cancer Study Group.
J Natl Cancer Inst, 2008 Jan 31; 100(3). PMID: 18230798
Short preoperative treatment with erlotinib inhibits tumor cell proliferation in hormone receptor-positive breast cancers.
Marta Guix, Nara de Matos Granja, +15 authors, Carlos L Arteaga.
J Clin Oncol, 2008 Jan 09; 26(6). PMID: 18180460
Proliferation markers and survival in early breast cancer: a systematic review and meta-analysis of 85 studies in 32,825 patients.
R Stuart-Harris, C Caldas, S E Pinder, P Pharoah.
Breast, 2008 May 06; 17(4). PMID: 18455396
Highly Cited. Systematic Review.
Outcome prediction for estrogen receptor-positive breast cancer based on postneoadjuvant endocrine therapy tumor characteristics.
Matthew J Ellis, Yu Tao, +9 authors, Mitch Dowsett.
J Natl Cancer Inst, 2008 Sep 25; 100(19). PMID: 18812550    Free PMC article.
Highly Cited.
The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative: methods of the EGAPP Working Group.
Steven M Teutsch, Linda A Bradley, +7 authors, EGAPP Working Group.
Genet Med, 2008 Sep 25; 11(1). PMID: 18813139    Free PMC article.
Highly Cited.
Membranous and cytoplasmic staining of Ki67 is associated with HER2 and ER status in invasive breast carcinoma.
Dana Faratian, Alison Munro, Christopher Twelves, John M S Bartlett.
Histopathology, 2009 Feb 12; 54(2). PMID: 19207951
Breast cancer subtypes and response to docetaxel in node-positive breast cancer: use of an immunohistochemical definition in the BCIRG 001 trial.
Judith Hugh, John Hanson, +11 authors, Charles Vogel.
J Clin Oncol, 2009 Feb 11; 27(8). PMID: 19204205    Free PMC article.
Highly Cited.
Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer.
Maggie C U Cheang, Stephen K Chia, +10 authors, Torsten O Nielsen.
J Natl Cancer Inst, 2009 May 14; 101(10). PMID: 19436038    Free PMC article.
Highly Cited.
Improved surgical outcomes for breast cancer patients receiving neoadjuvant aromatase inhibitor therapy: results from a multicenter phase II trial.
John A Olson, G Thomas Budd, +10 authors, Matthew J Ellis.
J Am Coll Surg, 2009 May 30; 208(5). PMID: 19476859    Free PMC article.
Ki67 expression and docetaxel efficacy in patients with estrogen receptor-positive breast cancer.
Frédérique Penault-Llorca, Fabrice André, +11 authors, Henri Roché.
J Clin Oncol, 2009 Apr 22; 27(17). PMID: 19380452
The prognostic significance of Ki67 before and after neoadjuvant chemotherapy in breast cancer.
Robin L Jones, Janine Salter, +5 authors, Mitchell Dowsett.
Breast Cancer Res Treat, 2008 Jul 02; 116(1). PMID: 18592370
Cetuximab-based immunotherapy and radioimmunotherapy of head and neck squamous cell carcinoma.
Gang Niu, Xilin Sun, +5 authors, Xiaoyuan Chen.
Clin Cancer Res, 2010 Mar 11; 16(7). PMID: 20215534    Free PMC article.
Strategies for subtypes--dealing with the diversity of breast cancer: highlights of the St. Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011.
A Goldhirsch, W C Wood, +4 authors, Panel members.
Ann Oncol, 2011 Jun 29; 22(8). PMID: 21709140    Free PMC article.
Highly Cited.
Comparison of visual and automated assessment of Ki-67 proliferative activity and their impact on outcome in primary operable invasive ductal breast cancer.
Z M A Mohammed, D C McMillan, +5 authors, J Edwards.
Br J Cancer, 2012 Jan 19; 106(2). PMID: 22251968    Free PMC article.
Use of neoadjuvant data to design adjuvant endocrine therapy trials for breast cancer.
Rodrigo Goncalves, Cynthia Ma, +2 authors, Matthew James Ellis.
Nat Rev Clin Oncol, 2012 Mar 01; 9(4). PMID: 22371132    Free PMC article.
Review.
Respective prognostic value of genomic grade and histological proliferation markers in early stage (pN0) breast carcinoma.
Fabien Reyal, Marc A Bollet, +9 authors, Xavier Sastre-Garau.
PLoS One, 2012 Apr 25; 7(4). PMID: 22529987    Free PMC article.
Assessment of the contribution of the IHC4+C score to decision making in clinical practice in early breast cancer.
S Barton, L Zabaglo, +6 authors, M Dowsett.
Br J Cancer, 2012 Apr 26; 106(11). PMID: 22531639    Free PMC article.
Aurora kinase A outperforms Ki67 as a prognostic marker in ER-positive breast cancer.
H R Ali, S-J Dawson, +3 authors, C Caldas.
Br J Cancer, 2012 Apr 28; 106(11). PMID: 22538974    Free PMC article.
[Assessment of proliferation: core biopsy or resection specimen? Discrepancies in breast cancer with low and high proliferation].
E C Obermann, S Eppenberger-Castori, C Tapia.
Pathologe, 2012 May 12; 33(3). PMID: 22576598
Review.
How reliable is Ki-67 immunohistochemistry in grade 2 breast carcinomas? A QA study of the Swiss Working Group of Breast- and Gynecopathologists.
Zsuzsanna Varga, Joachim Diebold, +16 authors, Hans-Anton Lehr.
PLoS One, 2012 Jun 05; 7(5). PMID: 22662150    Free PMC article.
Feasibility study of FDG PET as an indicator of early response to aromatase inhibitors and trastuzumab in a heterogeneous group of breast cancer patients.
Brenda F Kurland, Vijayakrishna K Gadi, +8 authors, Hannah M Linden.
EJNMMI Res, 2012 Jun 27; 2(1). PMID: 22731662    Free PMC article.
Breast density predicts endocrine treatment outcome in the adjuvant setting.
Jack Cuzick.
Breast Cancer Res, 2012 Aug 15; 14(4). PMID: 22889086    Free PMC article.
Long-term outcome of neoadjuvant systemic therapy for locally advanced breast cancer in routine clinical practice.
Domenico Angelucci, Nicola Tinari, +13 authors, Clara Natoli.
J Cancer Res Clin Oncol, 2012 Oct 12; 139(2). PMID: 23052698    Free PMC article.
[Translational research and diagnostics for breast cancer].
H H Kreipe.
Pathologe, 2012 Oct 16; 33 Suppl 2. PMID: 23064514
Review.
Publication of tumor marker research results: the necessity for complete and transparent reporting.
Lisa M McShane, Daniel F Hayes.
J Clin Oncol, 2012 Oct 17; 30(34). PMID: 23071235    Free PMC article.
Review.
Embryonic morphogen nodal promotes breast cancer growth and progression.
Daniela F Quail, Guihua Zhang, +7 authors, Lynne-Marie Postovit.
PLoS One, 2012 Nov 13; 7(11). PMID: 23144858    Free PMC article.
Prognostic value of Ki-67 for prostate cancer death in a conservatively managed cohort.
G Fisher, Z H Yang, +5 authors, Transatlantic Prostate Group.
Br J Cancer, 2013 Jan 19; 108(2). PMID: 23329234    Free PMC article.
[Breast cancer. Individualized therapy concepts].
N Harbeck, R Wuerstlein.
Internist (Berl), 2013 Feb 02; 54(2). PMID: 23371261
Assessment of early tumor response to cytotoxic chemotherapy with dynamic contrast-enhanced ultrasound in human breast cancer xenografts.
Jian-Wei Wang, Wei Zheng, +5 authors, Jian-Hua Zhou.
PLoS One, 2013 Mar 08; 8(3). PMID: 23469274    Free PMC article.
Comparison of circulating tumor cells (CTC) in peripheral blood and disseminated tumor cells in the bone marrow (DTC-BM) of breast cancer patients.
Christian Schindlbeck, Ulrich Andergassen, +6 authors, Brigitte Rack.
J Cancer Res Clin Oncol, 2013 Mar 26; 139(6). PMID: 23525580
Effect of intermittent dosing regimens of erlotinib on methylnitrosourea-induced mammary carcinogenesis.
Ronald A Lubet, Eva Szabo, +7 authors, Clinton J Grubbs.
Cancer Prev Res (Phila), 2013 Mar 28; 6(5). PMID: 23531447    Free PMC article.
The combination of Ki67, histological grade and estrogen receptor status identifies a low-risk group among 1,854 chemo-naïve women with N0/N1 primary breast cancer.
Carina Strand, Martin Bak, +13 authors, Mårten Fernö.
Springerplus, 2013 Apr 06; 2(1). PMID: 23560250    Free PMC article.
Is TIMP-1 immunoreactivity alone or in combination with other markers a predictor of benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial?
Alison F Munro, Annette Bartels, +4 authors, John M S Bartlett.
Breast Cancer Res, 2013 Apr 11; 15(2). PMID: 23570501    Free PMC article.
Tailoring treatment for ductal intraepithelial neoplasia of the breast according to Ki-67 and molecular phenotype.
M Lazzeroni, A Guerrieri-Gonzaga, +12 authors, G Pruneri.
Br J Cancer, 2013 Apr 13; 108(8). PMID: 23579208    Free PMC article.
A comparison of Ki-67 and mitotic count as prognostic markers for metastatic pancreatic and midgut neuroendocrine neoplasms.
M S Khan, T V Luong, +3 authors, T Meyer.
Br J Cancer, 2013 Apr 13; 108(9). PMID: 23579216    Free PMC article.
Mass spectrometry imaging for in situ kinetic histochemistry.
Katherine B Louie, Benjamin P Bowen, +5 authors, Trent R Northen.
Sci Rep, 2013 Apr 16; 3. PMID: 23584513    Free PMC article.
Ki-67 labeling in canine perianal glands neoplasms: a novel approach for immunohistological diagnostic and prognostic.
Rodrigo Storti Pereira, Augusto Schweigert, +3 authors, Gisele Fabrino Machado.
BMC Vet Res, 2013 Apr 23; 9. PMID: 23601191    Free PMC article.
Effectiveness of neoadjuvant trastuzumab and chemotherapy in HER2-overexpressing breast cancer.
Clara Natoli, Patrizia Vici, +17 authors, Teresa Gamucci.
J Cancer Res Clin Oncol, 2013 Apr 23; 139(7). PMID: 23604446    Free PMC article.
Aromatase inhibition 2013: clinical state of the art and questions that remain to be solved.
Per Eystein Lønning, Hans Petter Eikesdal.
Endocr Relat Cancer, 2013 Apr 30; 20(4). PMID: 23625614    Free PMC article.
Review.
Ki-67 is a prognostic parameter in breast cancer patients: results of a large population-based cohort of a cancer registry.
E C Inwald, M Klinkhammer-Schalke, +4 authors, O Ortmann.
Breast Cancer Res Treat, 2013 May 16; 139(2). PMID: 23674192    Free PMC article.
Highly Cited.
Digital quantification of gene expression in sequential breast cancer biopsies reveals activation of an immune response.
Rinath M Jeselsohn, Lillian Werner, +11 authors, Steven E Come.
PLoS One, 2013 Jun 07; 8(5). PMID: 23741308    Free PMC article.
PET/CT and breast cancer subtypes.
Laura Gilardi, Marco Colleoni, Giovanni Paganelli.
Eur J Nucl Med Mol Imaging, 2013 Jun 12; 40(9). PMID: 23748238
[Breast cancer: current recommendations for pathologists on the basis of the S3 guidelines].
A Lebeau, H Kreipe, +2 authors, R Kreienberg.
Pathologe, 2013 Jun 25; 34(4). PMID: 23793365
A new Ki-67 / E-cadherin cocktail reduces inter-observer variation of the calculated proliferative index.
Golan Bubis, Ohad Hilly, +4 authors, Lea Rath-Wolfson.
Pathol Oncol Res, 2013 Jul 09; 19(4). PMID: 23832820
Luminal breast cancer: from biology to treatment.
Michail Ignatiadis, Christos Sotiriou.
Nat Rev Clin Oncol, 2013 Jul 25; 10(9). PMID: 23881035
Review.
Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013.
A Goldhirsch, E P Winer, +5 authors, Panel members.
Ann Oncol, 2013 Aug 07; 24(9). PMID: 23917950    Free PMC article.
Highly Cited.
[Gene expression analysis in breast cancer. A new diagnostic tool in pathology].
C Denkert.
Pathologe, 2013 Aug 13; 34(5). PMID: 23934410
Review.
Preoperative core needle biopsy is accurate in determining molecular subtypes in invasive breast cancer.
Xiaosong Chen, Long Sun, +10 authors, Kunwei Shen.
BMC Cancer, 2013 Aug 21; 13. PMID: 23957561    Free PMC article.
Ki67-BCL2 index in prognosis of malignant peritoneal mesothelioma.
Krishna Pillai, Mohammad H Pourgholami, Terence C Chua, David L Morris.
Am J Cancer Res, 2013 Aug 27; 3(4). PMID: 23977450    Free PMC article.
Prediction of late distant recurrence in patients with oestrogen-receptor-positive breast cancer: a prospective comparison of the breast-cancer index (BCI) assay, 21-gene recurrence score, and IHC4 in the TransATAC study population.
Dennis C Sgroi, Ivana Sestak, +9 authors, Mitch Dowsett.
Lancet Oncol, 2013 Sep 17; 14(11). PMID: 24035531    Free PMC article.
Highly Cited.
p53 accumulation is a strong predictor of recurrence in estrogen receptor-positive breast cancer patients treated with aromatase inhibitors.
Mitsugu Yamamoto, Mitsuchika Hosoda, +6 authors, Hiroko Yamashita.
Cancer Sci, 2013 Oct 15; 105(1). PMID: 24118529    Free PMC article.
Immunohistochemical quantification of the vitamin B12 transport protein (TCII), cell surface receptor (TCII-R) and Ki-67 in human tumor xenografts.
Annette M Sysel, Victor E Valli, Ray B Nagle, Joseph A Bauer.
Anticancer Res, 2013 Oct 15; 33(10). PMID: 24122983    Free PMC article.
Genomic instability: a stronger prognostic marker than proliferation for early stage luminal breast carcinomas.
Anne Vincent-Salomon, Vanessa Benhamo, +13 authors, Olivier Delattre.
PLoS One, 2013 Oct 22; 8(10). PMID: 24143191    Free PMC article.
The effect of metformin on apoptosis in a breast cancer presurgical trial.
M Cazzaniga, A DeCensi, +11 authors, B Bonanni.
Br J Cancer, 2013 Oct 26; 109(11). PMID: 24157825    Free PMC article.
Quantitative assessment Ki-67 score for prediction of response to neoadjuvant chemotherapy in breast cancer.
Jason R Brown, Michael P DiGiovanna, +2 authors, David L Rimm.
Lab Invest, 2013 Nov 06; 94(1). PMID: 24189270
The use of digital images improves reproducibility of the ki-67 labeling index as a proliferation marker in breast cancer.
András Vörös, Erika Csörgő, +3 authors, Gábor Cserni.
Pathol Oncol Res, 2013 Nov 10; 20(2). PMID: 24202856
An international Ki67 reproducibility study.
Mei-Yin C Polley, Samuel C Y Leung, +16 authors, International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group.
J Natl Cancer Inst, 2013 Nov 10; 105(24). PMID: 24203987    Free PMC article.
Highly Cited.
Quantifying the ki-67 heterogeneity profile in prostate cancer.
Shane Mesko, Patrick Kupelian, +3 authors, Mitchell Kamrava.
Prostate Cancer, 2013 Nov 14; 2013. PMID: 24222860    Free PMC article.
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.
Suzanne A Eccles, Eric O Aboagye, +84 authors, Alastair M Thompson.
Breast Cancer Res, 2013 Nov 30; 15(5). PMID: 24286369    Free PMC article.
Highly Cited. Review.
Progesterone receptor expression is an independent prognostic variable in early breast cancer: a population-based study.
C A Purdie, P Quinlan, +4 authors, A M Thompson.
Br J Cancer, 2013 Dec 05; 110(3). PMID: 24300977    Free PMC article.
Increased expression of mdig predicts poorer survival of the breast cancer patients.
Chitra Thakur, Yongju Lu, +3 authors, Fei Chen.
Gene, 2013 Dec 07; 535(2). PMID: 24309373    Free PMC article.
The prognostic value of mitotic activity index (MAI), phosphohistone H3 (PPH3), cyclin B1, cyclin A, and Ki67, alone and in combinations, in node-negative premenopausal breast cancer.
Marie Klintman, Carina Strand, +11 authors, Mårten Fernö.
PLoS One, 2013 Dec 11; 8(12). PMID: 24324728    Free PMC article.
Semi-automated evaluation of Ki-67 index in invasive ductal carcinoma of the breast.
Cristian Suciu, Anca Muresan, +3 authors, Marius Raica.
Oncol Lett, 2013 Dec 19; 7(1). PMID: 24348830    Free PMC article.
Association of molecular subtypes with Ki-67 changes in untreated breast cancer patients undergoing pre-surgical trials.
S Gandini, A Guerrieri-Gonzaga, +8 authors, A DeCensi.
Ann Oncol, 2013 Dec 20; 25(3). PMID: 24351403    Free PMC article.
Biological effects of green tea capsule supplementation in pre-surgery postmenopausal breast cancer patients.
Steven S Yu, Darcy V Spicer, +4 authors, Anna H Wu.
Front Oncol, 2014 Jan 01; 3. PMID: 24380073    Free PMC article.
Tamoxifen versus tamoxifen plus doxorubicin and cyclophosphamide as adjuvant therapy for node-positive postmenopausal breast cancer: results of a Japan Clinical Oncology Group Study (JCOG9401).
Tadahiko Shien, Hiroji Iwata, +7 authors, Haruhiko Fukuda.
Int J Clin Oncol, 2014 Jan 08; 19(6). PMID: 24395447
[Determination of proliferation in breast cancer by immunohistochemical detection of Ki-67].
M Christgen, W Winkens, H H Kreipe.
Pathologe, 2014 Jan 15; 35(1). PMID: 24414612
Breast Cancer Biomarkers: Utility in Clinical Practice.
Fanny Le Du, Naoto T Ueno, Ana M Gonzalez-Angulo.
Curr Breast Cancer Rep, 2014 Jan 15; 5(4). PMID: 24416469    Free PMC article.
Prognostic prostate tissue biomarkers of potential clinical use.
Theodorus H Van der Kwast.
Virchows Arch, 2014 Feb 04; 464(3). PMID: 24487790
Review.
Differences in breast carcinoma immunohistochemical subtypes between immigrant Arab and European women.
Fanny Preat, Philippe Simon, Jean-Christophe Noel.
Diagn Pathol, 2014 Feb 06; 9. PMID: 24495621    Free PMC article.
Targeted biomarker profiling of matched primary and metastatic estrogen receptor positive breast cancers.
Erica B Schleifman, Rupal Desai, +13 authors, Mark R Lackner.
PLoS One, 2014 Feb 13; 9(2). PMID: 24520381    Free PMC article.
Cutaneous and cardiac toxicity of concurrent trastuzumab and adjuvant breast radiotherapy: a single institution series.
Icro Meattini, Sara Cecchini, +10 authors, Lorenzo Livi.
Med Oncol, 2014 Feb 19; 31(4). PMID: 24535610
Genomic profiling in luminal breast cancer.
Oleg Gluz, Daniel Hofmann, +3 authors, Nadia Harbeck.
Breast Care (Basel), 2014 Feb 20; 8(6). PMID: 24550749    Free PMC article.
Review.
Clinicopathological significance of androgen receptor, HER2, Ki-67 and EGFR expressions in salivary duct carcinoma.
Tatsuo Masubuchi, Yuichiro Tada, +8 authors, Toshitaka Nagao.
Int J Clin Oncol, 2014 Feb 21; 20(1). PMID: 24553861
Estrogen receptor α-coupled Bmi1 regulation pathway in breast cancer and its clinical implications.
Huali Wang, Haijing Liu, +10 authors, Bo Zhang.
BMC Cancer, 2014 Feb 25; 14. PMID: 24559156    Free PMC article.
Invasive lobular carcinoma of the breast: long-term prognostic value of Ki67 and histological grade, alone and in combination with estrogen receptor.
Ulrik Narbe, Pär-Ola Bendahl, +3 authors, Mårten Fernö.
Springerplus, 2014 Feb 26; 3. PMID: 24567879    Free PMC article.
Complexity in regulation of microRNA machinery components in invasive breast carcinoma.
Sun Young Kwon, Jae-ho Lee, +4 authors, Shin Kim.
Pathol Oncol Res, 2014 Feb 28; 20(3). PMID: 24574065
Subtype classification for prediction of prognosis of breast cancer from a biomarker panel: correlations and indications.
Chuang Chen, Jing-Ping Yuan, +6 authors, Yan Li.
Int J Nanomedicine, 2014 Mar 05; 9. PMID: 24591826    Free PMC article.
Presurgical trial of metformin in overweight and obese patients with newly diagnosed breast cancer.
Kevin Kalinsky, Katherine D Crew, +9 authors, Dawn L Hershman.
Cancer Invest, 2014 Mar 13; 32(4). PMID: 24605899    Free PMC article.
Multi-level gene expression signatures, but not binary, outperform Ki67 for the long term prognostication of breast cancer patients.
Nicholas P Tobin, Linda S Lindström, +3 authors, Kristian Wennmalm.
Mol Oncol, 2014 Mar 19; 8(3). PMID: 24630985    Free PMC article.
Quantum dot-based immunofluorescent imaging of Ki67 and identification of prognostic value in HER2-positive (non-luminal) breast cancer.
Jin-Zhong Sun, Chuang Chen, +3 authors, Sheng-Rong Sun.
Int J Nanomedicine, 2014 Mar 22; 9. PMID: 24648732    Free PMC article.
Joint detection of multiple immunohistochemical indices and clinical significance in breast cancer.
En-Qi Qiao, Minghua Ji, +9 authors, Ji-Hai Tang.
Mol Clin Oncol, 2014 Mar 22; 1(4). PMID: 24649232    Free PMC article.
Evaluation and correlation of risk recurrence in early breast cancer assessed by Oncotype DX®, clinicopathological markers and tumor cell dissemination in the blood and bone marrow.
Bahriye Aktas, Agnes Bankfalvi, +2 authors, Sabine Kasimir-Bauer.
Mol Clin Oncol, 2014 Mar 22; 1(6). PMID: 24649291    Free PMC article.
A methodology to ensure and improve accuracy of Ki67 labelling index estimation by automated digital image analysis in breast cancer tissue.
Arvydas Laurinavicius, Benoit Plancoulaine, +8 authors, Catherine Bor.
Breast Cancer Res, 2014 Apr 09; 16(2). PMID: 24708745    Free PMC article.
Erlotinib, erlotinib-sulindac versus placebo: a randomized, double-blind, placebo-controlled window trial in operable head and neck cancer.
Neil D Gross, Julie E Bauman, +16 authors, Jennifer R Grandis.
Clin Cancer Res, 2014 Apr 15; 20(12). PMID: 24727329    Free PMC article.
Mechanistic elucidation of the antitumor properties of withaferin a in breast cancer.
Arumugam Nagalingam, Panjamurthy Kuppusamy, +2 authors, Neeraj K Saxena.
Cancer Res, 2014 Apr 16; 74(9). PMID: 24732433    Free PMC article.
miR-221/222 control luminal breast cancer tumor progression by regulating different targets.
Patrizia Dentelli, Matteo Traversa, +10 authors, Maria Felice Brizzi.
Cell Cycle, 2014 Apr 17; 13(11). PMID: 24736554    Free PMC article.
Interdisciplinary GoR level III Guidelines for the Diagnosis, Therapy and Follow-up Care of Breast Cancer: Short version - AWMF Registry No.: 032-045OL AWMF-Register-Nummer: 032-045OL - Kurzversion 3.0, Juli 2012.
R Kreienberg, U-S Albert, +3 authors, A Wöckel.
Geburtshilfe Frauenheilkd, 2014 Apr 29; 73(6). PMID: 24771925    Free PMC article.
Can ki-67 play a role in prediction of breast cancer patients' response to neoadjuvant chemotherapy?
Juhasz-Böss Ingolf, Mavrova Russalina, +6 authors, Herr Daniel.
Biomed Res Int, 2014 May 02; 2014. PMID: 24783217    Free PMC article.
Evaluation of FLT-PET-CT as an imaging biomarker of proliferation in primary breast cancer.
D K Woolf, M Beresford, +9 authors, A Makris.
Br J Cancer, 2014 May 17; 110(12). PMID: 24832174    Free PMC article.
Different methods of pretreatment Ki-67 labeling index evaluation in core biopsies of breast cancer patients treated with neoadjuvant chemotherapy and their relation to response to therapy.
András Vörös, Erika Csörgő, +5 authors, Gábor Cserni.
Pathol Oncol Res, 2014 May 27; 21(1). PMID: 24859973
Ki-67 is a strong prognostic marker of non-small cell lung cancer when tissue heterogeneity is considered.
Kazuhiro Tabata, Tomonori Tanaka, +4 authors, Junya Fukuoka.
BMC Clin Pathol, 2014 May 27; 14. PMID: 24860257    Free PMC article.
Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery.
Daniel G Booth, Masatoshi Takagi, +8 authors, Paola Vagnarelli.
Elife, 2014 May 29; 3. PMID: 24867636    Free PMC article.
Survivin family proteins as novel molecular determinants of doxorubicin resistance in organotypic human breast tumors.
Alice Faversani, Valentina Vaira, +6 authors, Silvano Bosari.
Breast Cancer Res, 2014 Jun 03; 16(3). PMID: 24886669    Free PMC article.
Chromatin CKAP2, a new proliferation marker, as independent prognostic indicator in breast cancer.
Han-Seong Kim, Jae-Soo Koh, +12 authors, Kyeong-Man Hong.
PLoS One, 2014 Jun 03; 9(6). PMID: 24887265    Free PMC article.
Tumor microenvironment of metastasis and risk of distant metastasis of breast cancer.
Thomas E Rohan, Xiaonan Xue, +10 authors, Joan G Jones.
J Natl Cancer Inst, 2014 Jun 05; 106(8). PMID: 24895374    Free PMC article.
Highly Cited.
A novel model for Ki67 assessment in breast cancer.
Quinci Romero, Pär-Ola Bendahl, +2 authors, Signe Borgquist.
Diagn Pathol, 2014 Jun 18; 9. PMID: 24934660    Free PMC article.
Involvement of macrophage migration inhibitory factor and its receptor (CD74) in human breast cancer.
Vincent Richard, Nadège Kindt, +4 authors, Sven Saussez.
Oncol Rep, 2014 Jun 19; 32(2). PMID: 24939415    Free PMC article.
Evaluating the response of neoadjuvant chemotherapy for treatment of breast cancer: are tumor biomarkers and dynamic contrast enhanced MR images useful predictive tools?
Zijing Zhang, Wei Zhang, +10 authors, Qiang Zou.
J Thorac Dis, 2014 Jul 01; 6(6). PMID: 24977004    Free PMC article.
Postmastectomy radiotherapy for locally advanced breast cancer receiving neoadjuvant chemotherapy.
Icro Meattini, Sara Cecchini, +13 authors, Lorenzo Livi.
Biomed Res Int, 2014 Jul 22; 2014. PMID: 25045694    Free PMC article.
Tamoxifen plus tegafur-uracil (TUFT) versus tamoxifen plus Adriamycin (doxorubicin) and cyclophosphamide (ACT) as adjuvant therapy to treat node-positive premenopausal breast cancer (PreMBC): results of Japan Clinical Oncology Group Study 9404.
Tadahiko Shien, Hiroji Iwata, +8 authors, Haruhiko Fukuda.
Cancer Chemother Pharmacol, 2014 Jul 25; 74(3). PMID: 25055938    Free PMC article.
Ki67 expression and the effect of neo-adjuvant chemotherapy on luminal HER2-negative breast cancer.
Yoshiya Horimoto, Atsushi Arakawa, +7 authors, Mitsue Saito.
BMC Cancer, 2014 Jul 31; 14. PMID: 25073969    Free PMC article.
Prognostic value of ki-67 in breast carcinoma: tissue microarray method versus whole section analysis- potentials and pitfalls.
Natalija Dedić Plavetić, Jasminka Jakić-Razumović, +3 authors, Damir Vrbanec.
Pathol Oncol Res, 2014 Aug 07; 21(2). PMID: 25096394
Recurrent ESR1-CCDC170 rearrangements in an aggressive subset of oestrogen receptor-positive breast cancers.
Jamunarani Veeraraghavan, Ying Tan, +11 authors, Xiao-Song Wang.
Nat Commun, 2014 Aug 08; 5. PMID: 25099679    Free PMC article.
Biological subtypes of breast cancer: Prognostic and therapeutic implications.
Ozlem Yersal, Sabri Barutca.
World J Clin Oncol, 2014 Aug 13; 5(3). PMID: 25114856    Free PMC article.
Highly Cited. Review.
Gene Expression Analysis Reveals Distinct Pathways of Resistance to Bevacizumab in Xenograft Models of Human ER-Positive Breast Cancer.
Yesim Gökmen-Polar, Chirayu P Goswami, +9 authors, George W Sledge.
J Cancer, 2014 Aug 27; 5(8). PMID: 25157274    Free PMC article.
Progesterone receptor status and Ki-67 index may predict early relapse in luminal B/HER2 negative breast cancer patients: a retrospective study.
Yu Zong, Li Zhu, +7 authors, Kunwei Shen.
PLoS One, 2014 Aug 30; 9(8). PMID: 25170613    Free PMC article.
Obstacles to precision oncology: confronting current factors affecting the successful introduction of biomarkers to the clinic.
Ludmila Prudkin, Paolo Nuciforo.
Cell Oncol (Dordr), 2014 Sep 05; 38(1). PMID: 25185990
Review.
The effects of soy supplementation on gene expression in breast cancer: a randomized placebo-controlled study.
Moshe Shike, Ashley S Doane, +7 authors, Larry Norton.
J Natl Cancer Inst, 2014 Sep 06; 106(9). PMID: 25190728    Free PMC article.
Impact of intrinsic subtype on predicting axillary lymph node metastasis in breast cancer.
Masataka Sawaki, Ai Idota, +7 authors, Hiroji Iwata.
Oncol Lett, 2014 Sep 10; 8(4). PMID: 25202396    Free PMC article.
Heterogeneity of triple-negative breast cancer: mammographic, US, and MR imaging features according to androgen receptor expression.
Min Sun Bae, So Yeon Park, +6 authors, Woo Kyung Moon.
Eur Radiol, 2014 Sep 17; 25(2). PMID: 25224727
Paclitaxel-loaded PEG-PE-based micellar nanopreparations targeted with tumor-specific landscape phage fusion protein enhance apoptosis and efficiently reduce tumors.
Tao Wang, Shenghong Yang, +5 authors, Vladimir P Torchilin.
Mol Cancer Ther, 2014 Sep 23; 13(12). PMID: 25239936    Free PMC article.
Triple-negative vimentin-positive heterogeneous feline mammary carcinomas as a potential comparative model for breast cancer.
Diego Caliari, Valentina Zappulli, +4 authors, Massimo Castagnaro.
BMC Vet Res, 2014 Sep 25; 10. PMID: 25249140    Free PMC article.
Differential effects of metformin on breast cancer proliferation according to markers of insulin resistance and tumor subtype in a randomized presurgical trial.
Andrea DeCensi, Matteo Puntoni, +15 authors, Michael N Pollak.
Breast Cancer Res Treat, 2014 Sep 26; 148(1). PMID: 25253174    Free PMC article.
Prognostic significance of Ki-67 index value at the primary breast tumor in recurrent breast cancer.
Reiki Nishimura, Tomofumi Osako, +5 authors, Nobuyuki Arima.
Mol Clin Oncol, 2014 Oct 04; 2(6). PMID: 25279198    Free PMC article.
Novel approaches for quantifying protein biomarkers in gliomas: benefits and pitfalls.
Rikke H Dahlrot, Mia D Sørensen, +8 authors, Bjarne W Kristensen.
CNS Oncol, 2014 Oct 07; 3(4). PMID: 25286040    Free PMC article.
Invasive ductular carcinoma in 2 rhesus macaques (Macaca mulatta).
Amanda P Beck, Amos Brooks, Caroline J Zeiss.
Comp Med, 2014 Oct 09; 64(4). PMID: 25296018    Free PMC article.
Time dependence of biomarkers: non-proportional effects of immunohistochemical panels predicting relapse risk in early breast cancer.
J Stephen, G Murray, +13 authors, J M S Bartlett.
Br J Cancer, 2014 Oct 15; 111(12). PMID: 25314051    Free PMC article.
Identification of chemokine receptors as potential modulators of endocrine resistance in oestrogen receptor-positive breast cancers.
Ricardo Ribas, Zara Ghazoui, +5 authors, Lesley-Ann Martin.
Breast Cancer Res, 2014 Nov 02; 16(5). PMID: 25358600    Free PMC article.
Evaluation of Ki67 expression across distinct categories of breast cancer specimens: a population-based study of matched surgical specimens, core needle biopsies and tissue microarrays.
Gøril Knutsvik, Ingunn M Stefansson, +4 authors, Lars A Akslen.
PLoS One, 2014 Nov 07; 9(11). PMID: 25375149    Free PMC article.
Lobular breast cancers lack the inverse relationship between ER/PR status and cell growth rate characteristic of ductal cancers in two independent patient cohorts: implications for tumor biology and adjuvant therapy.
Hilda Wong, Silvia Lau, +4 authors, Richard J Epstein.
BMC Cancer, 2014 Nov 12; 14. PMID: 25385074    Free PMC article.
Pathological non-response to chemotherapy in a neoadjuvant setting of breast cancer: an inter-institutional study.
D Balmativola, C Marchiò, +26 authors, A Sapino.
Breast Cancer Res Treat, 2014 Nov 15; 148(3). PMID: 25395316    Free PMC article.
Automated Selection of Hotspots (ASH): enhanced automated segmentation and adaptive step finding for Ki67 hotspot detection in adrenal cortical cancer.
Hao Lu, Thomas G Papathomas, +5 authors, Andrew P Stubbs.
Diagn Pathol, 2014 Nov 26; 9. PMID: 25421287    Free PMC article.
Stable luciferase expression does not alter immunologic or in vivo growth properties of GL261 murine glioma cells.
Aaron J Clark, Michael Safaee, +7 authors, Andrew T Parsa.
J Transl Med, 2014 Dec 04; 12. PMID: 25464980    Free PMC article.
PTEN and Ki67 expression is associated with clinicopathologic features of non-small cell lung cancer.
Yong Ji, Mingfeng Zheng, +2 authors, Yijiang Chen.
J Biomed Res, 2014 Dec 04; 28(6). PMID: 25469115    Free PMC article.
Inclusion of KI67 significantly improves performance of the PREDICT prognostication and prediction model for early breast cancer.
Gordon C Wishart, Emad Rakha, +6 authors, Paul D P Pharoah.
BMC Cancer, 2014 Dec 05; 14. PMID: 25472026    Free PMC article.
TBCRC 008: early change in 18F-FDG uptake on PET predicts response to preoperative systemic therapy in human epidermal growth factor receptor 2-negative primary operable breast cancer.
Roisin M Connolly, Jeffrey P Leal, +23 authors, Vered Stearns.
J Nucl Med, 2014 Dec 06; 56(1). PMID: 25476537    Free PMC article.
Longitudinal noninvasive imaging of progesterone receptor as a predictive biomarker of tumor responsiveness to estrogen deprivation therapy.
Szeman Ruby Chan, Amy M Fowler, +6 authors, John A Katzenellenbogen.
Clin Cancer Res, 2014 Dec 19; 21(5). PMID: 25520392    Free PMC article.
An integrative analysis of PIK3CA mutation, PTEN, and INPP4B expression in terms of trastuzumab efficacy in HER2-positive breast cancer.
Aiko Sueta, Yutaka Yamamoto, +4 authors, Hirotaka Iwase.
PLoS One, 2014 Dec 30; 9(12). PMID: 25542038    Free PMC article.
Digital immunohistochemistry platform for the staining variation monitoring based on integration of image and statistical analyses with laboratory information system.
Aida Laurinaviciene, Benoit Plancoulaine, +7 authors, Arvydas Laurinavicius.
Diagn Pathol, 2015 Jan 08; 9 Suppl 1. PMID: 25565007    Free PMC article.
Automated image analysis in the study of lymphocyte subpopulation in eosinophilic oesophagitis.
Marcial García-Rojo, Joaquín Sánchez, +8 authors, Bartolomé López-Viedma.
Diagn Pathol, 2015 Jan 08; 9 Suppl 1. PMID: 25565117    Free PMC article.
Emerging understanding of multiscale tumor heterogeneity.
Michael J Gerdes, Anup Sood, +3 authors, Fiona Ginty.
Front Oncol, 2015 Jan 08; 4. PMID: 25566504    Free PMC article.
Review.
Immunohistochemical quantification of the cobalamin transport protein, cell surface receptor and Ki-67 in naturally occurring canine and feline malignant tumors and in adjacent normal tissues.
Annette M Sysel, Victor E Valli, Joseph A Bauer.
Oncotarget, 2015 Jan 31; 6(4). PMID: 25633912    Free PMC article.
Clinical and histopathological factors associated with Ki-67 expression in breast cancer patients.
Gul Alco, Atilla Bozdogan, +8 authors, Vahit Ozmen.
Oncol Lett, 2015 Feb 11; 9(3). PMID: 25663855    Free PMC article.
Ki-67/MIB-1 immunostaining in a cohort of human gliomas.
Anne J Skjulsvik, Jørgen N Mørk, Morten O Torp, Sverre H Torp.
Int J Clin Exp Pathol, 2015 Feb 13; 7(12). PMID: 25674263    Free PMC article.
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) upregulation in breast carcinoma contributes to tumor progression and predicts early tumor recurrence.
Eman Abdelzaher, Mohamed Farouk Mostafa.
Tumour Biol, 2015 Feb 17; 36(7). PMID: 25683484
An international study to increase concordance in Ki67 scoring.
Mei-Yin C Polley, Samuel C Y Leung, +28 authors, Torsten O Nielsen.
Mod Pathol, 2015 Feb 24; 28(6). PMID: 25698062
Highly Cited.
SDHB/SDHA immunohistochemistry in pheochromocytomas and paragangliomas: a multicenter interobserver variation analysis using virtual microscopy: a Multinational Study of the European Network for the Study of Adrenal Tumors (ENS@T).
Thomas G Papathomas, Lindsey Oudijk, +35 authors, Ronald R de Krijger.
Mod Pathol, 2015 Feb 28; 28(6). PMID: 25720320
PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effects.
Raúl Rincón, Ion Cristóbal, +10 authors, Federico Rojo.
Oncotarget, 2015 Mar 03; 6(6). PMID: 25726524    Free PMC article.
One-Year Neoadjuvant Endocrine Therapy in Breast Cancer.
Orsolya Rusz, András Vörös, +6 authors, Zsuzsanna Kahán.
Pathol Oncol Res, 2015 Mar 11; 21(4). PMID: 25753983
Prevention of chemically induced urinary bladder cancers by naproxen: protocols to reduce gastric toxicity in humans do not alter preventive efficacy.
Ronald A Lubet, James M Scheiman, +6 authors, Clinton J Grubbs.
Cancer Prev Res (Phila), 2015 Mar 13; 8(4). PMID: 25762530    Free PMC article.
Observer performance in the use of digital and optical microscopy for the interpretation of tissue-based biomarkers.
Marios A Gavrielides, Catherine Conway, +2 authors, Stephen M Hewitt.
Anal Cell Pathol (Amst), 2014 Jan 01; 2014. PMID: 25763314    Free PMC article.
MR mammography using diffusion-weighted imaging in evaluating breast cancer: a correlation with proliferation index.
Cristina Molinari, Paola Clauser, +5 authors, Massimo Bazzocchi.
Radiol Med, 2015 Mar 18; 120(10). PMID: 25776017
Ki67--no evidence for its use in node-positive breast cancer.
Fabrice Andre, Monica Arnedos, +2 authors, Suzette Delaloge.
Nat Rev Clin Oncol, 2015 Mar 18; 12(5). PMID: 25781576
Review.
Quantum dots-based quantitative and in situ multiple imaging on ki67 and cytokeratin to improve ki67 assessment in breast cancer.
Jing Ping Yuan, Lin Wei Wang, +7 authors, Yan Li.
PLoS One, 2015 Apr 10; 10(4). PMID: 25856425    Free PMC article.
Effect of tamoxifen and raloxifene on the proliferative activity of the breast epithelium in premenopausal women.
Miliana T Lucato, Ruffo Freitas-Junior, +4 authors, Leonardo R Soares.
Clin Med Insights Oncol, 2015 Apr 11; 9. PMID: 25861235    Free PMC article.
Standardization for Ki-67 assessment in moderately differentiated breast cancer. A retrospective analysis of the SAKK 28/12 study.
Zsuzsanna Varga, Estelle Cassoly, +6 authors, Thomas Ruhstaller.
PLoS One, 2015 Apr 18; 10(4). PMID: 25885288    Free PMC article.
Mechanisms of aromatase inhibitor resistance.
Cynthia X Ma, Tomás Reinert, Izabela Chmielewska, Matthew J Ellis.
Nat Rev Cancer, 2015 Apr 25; 15(5). PMID: 25907219
Highly Cited. Review.
An interobserver reproducibility analysis of Ki67 visual assessment in breast cancer.
Ruohong Shui, Baohua Yu, +2 authors, Wentao Yang.
PLoS One, 2015 May 02; 10(5). PMID: 25932921    Free PMC article.
Clinicopathologic Characteristics of Oestrogen Receptor-Positive/Progesterone Receptor-Negative/Her2-Negative Breast Cancer According to a Novel Definition of Negative Progesterone Receptor Status: A Large Population-Based Study from China.
An-qi Li, Shu-ling Zhou, +4 authors, Wen-tao Yang.
PLoS One, 2015 May 06; 10(5). PMID: 25938238    Free PMC article.
Resolving quandaries: basaloid adenoid cystic carcinoma or breast cylindroma? The role of massively parallel sequencing.
Nicola Fusco, Pierre-Emmanuel Colombo, +8 authors, Britta Weigelt.
Histopathology, 2015 May 09; 68(2). PMID: 25951887    Free PMC article.
From bench to bedside: What do we know about hormone receptor-positive and human epidermal growth factor receptor 2-positive breast cancer?
Victoria Shang Wu, Noriko Kanaya, +2 authors, Shiuan Chen.
J Steroid Biochem Mol Biol, 2015 May 23; 153. PMID: 25998416    Free PMC article.
Review.
Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration.
V Bossuyt, E Provenzano, +18 authors, Breast International Group-North American Breast Cancer Group (BIG-NABCG) collaboration.
Ann Oncol, 2015 May 29; 26(7). PMID: 26019189    Free PMC article.
Review.
Honokiol abrogates leptin-induced tumor progression by inhibiting Wnt1-MTA1-β-catenin signaling axis in a microRNA-34a dependent manner.
Dimiter B Avtanski, Arumugam Nagalingam, +4 authors, Dipali Sharma.
Oncotarget, 2015 Jun 04; 6(18). PMID: 26036628    Free PMC article.
Androgen Receptor (AR), E-Cadherin, and Ki-67 as Emerging Targets and Novel Prognostic Markers in Triple-Negative Breast Cancer (TNBC) Patients.
Giuseppina Rosaria Rita Ricciardi, Barbara Adamo, +6 authors, Vincenzo Adamo.
PLoS One, 2015 Jun 04; 10(6). PMID: 26039245    Free PMC article.
Cancer across the tree of life: cooperation and cheating in multicellularity.
C Athena Aktipis, Amy M Boddy, +4 authors, Gerald S Wilkinson.
Philos Trans R Soc Lond B Biol Sci, 2015 Jun 10; 370(1673). PMID: 26056363    Free PMC article.
Highly Cited. Review.
Immunohistochemical Predictors of Bone Metastases in Breast Cancer Patients.
Piotr Winczura, Katarzyna Sosińska-Mielcarek, +10 authors, Jacek Jassem.
Pathol Oncol Res, 2015 Jun 13; 21(4). PMID: 26062800    Free PMC article.
Comparison of digital image analysis and visual scoring of KI-67 in prostate cancer prognosis after prostatectomy.
Patrice Desmeules, Hélène Hovington, +6 authors, Vincent Fradet.
Diagn Pathol, 2015 Jun 14; 10. PMID: 26070608    Free PMC article.
Using proliferative markers and Oncotype DX in therapeutic decision-making for breast cancer: the B.C. experience.
E Baxter, L Gondara, +5 authors, S Tyldesley.
Curr Oncol, 2015 Jun 20; 22(3). PMID: 26089718    Free PMC article.
Sprouty 1 predicts prognosis in human epithelial ovarian cancer.
Samar Masoumi-Moghaddam, Afshin Amini, +2 authors, David L Morris.
Am J Cancer Res, 2015 Jun 24; 5(4). PMID: 26101716    Free PMC article.
Epidermal growth factor receptor immunohistochemistry: new opportunities in metastatic colorectal cancer.
Ryan A Hutchinson, Richard A Adams, +3 authors, Peter W Hamilton.
J Transl Med, 2015 Jul 08; 13. PMID: 26149458    Free PMC article.
Review.
Differences in Clinical Outcomes between Luminal A and B Type Breast Cancers according to the St. Gallen Consensus 2013.
Hyo Jung Ahn, Soo Jin Jung, +2 authors, Hye-Kyoung Yoon.
J Breast Cancer, 2015 Jul 15; 18(2). PMID: 26155291    Free PMC article.
Clinical and genomic analysis of a randomised phase II study evaluating anastrozole and fulvestrant in postmenopausal patients treated for large operable or locally advanced hormone-receptor-positive breast cancer.
Nathalie Quenel-Tueux, Marc Debled, +18 authors, Richard Iggo.
Br J Cancer, 2015 Jul 15; 113(4). PMID: 26171933    Free PMC article.
Evaluation of an Optimal Cut-Off Point for the Ki-67 Index as a Prognostic Factor in Primary Breast Cancer: A Retrospective Study.
Rumiko Tashima, Reiki Nishimura, +6 authors, Nobuyuki Arima.
PLoS One, 2015 Jul 16; 10(7). PMID: 26177501    Free PMC article.
Clinical utility of the IHC4+C score in oestrogen receptor-positive early breast cancer: a prospective decision impact study.
B Yeo, L Zabaglo, +3 authors, M Dowsett.
Br J Cancer, 2015 Jul 17; 113(3). PMID: 26180920    Free PMC article.
Standardization of pathologic evaluation and reporting of postneoadjuvant specimens in clinical trials of breast cancer: recommendations from an international working group.
Elena Provenzano, Veerle Bossuyt, +17 authors, Residual Disease Characterization Working Group of the Breast International Group-North American Breast Cancer Group Collaboration.
Mod Pathol, 2015 Jul 25; 28(9). PMID: 26205180
Highly Cited.
Digital imaging in the immunohistochemical evaluation of the proliferation markers Ki67, MCM2 and Geminin, in early breast cancer, and their putative prognostic value.
Shalaka Joshi, Johnathan Watkins, +4 authors, Sarah E Pinder.
BMC Cancer, 2015 Jul 25; 15. PMID: 26205655    Free PMC article.
Relative Effectiveness of Letrozole Compared With Tamoxifen for Patients With Lobular Carcinoma in the BIG 1-98 Trial.
Otto Metzger Filho, Anita Giobbie-Hurder, +12 authors, Aron Goldhirsch.
J Clin Oncol, 2015 Jul 29; 33(25). PMID: 26215945    Free PMC article.
The role of the pathologist in the decision-making process.
Angelo Paolo Dei Tos.
EJC Suppl, 2013 Sep 01; 11(2). PMID: 26217110    Free PMC article.
Review.
Optimal approach in early breast cancer: Adjuvant and neoadjuvant treatment.
J Ribeiro, B Sousa, F Cardoso.
EJC Suppl, 2013 Sep 01; 11(2). PMID: 26217109    Free PMC article.
Review.
Development and verification of the PAM50-based Prosigna breast cancer gene signature assay.
Brett Wallden, James Storhoff, +16 authors, Joel S Parker.
BMC Med Genomics, 2015 Aug 25; 8. PMID: 26297356    Free PMC article.
Highly Cited.
Correlation Between Clinical-Pathologic Factors and Long-Term Follow-Up in Young Breast Cancer Patients.
Yue Zhao, Xiaoqiu Dong, +2 authors, Dongwei Zhang.
Transl Oncol, 2015 Aug 28; 8(4). PMID: 26310372    Free PMC article.
Impact of immunohistochemistry-based molecular subtype on chemosensitivity and survival in Hispanic breast cancer patients following neoadjuvant chemotherapy.
Rodolfo Gómez, Carlos Andrés Ossa, +13 authors, Héctor García.
Ecancermedicalscience, 2015 Sep 01; 9. PMID: 26316883    Free PMC article.
Conference report from the 2015 OECI Oncology Days, Portugal, 22-24 June-tumour heterogeneity and next generation sequencing: morphology and technology.
Linda Cairns.
Ecancermedicalscience, 2015 Sep 01; 9. PMID: 26316886    Free PMC article.
Comparing computer-generated and pathologist-generated tumour segmentations for immunohistochemical scoring of breast tissue microarrays.
Shazia Akbar, Lee B Jordan, +2 authors, Stephen J McKenna.
Br J Cancer, 2015 Sep 09; 113(7). PMID: 26348443    Free PMC article.
A Phase II Study of 3'-Deoxy-3'-18F-Fluorothymidine PET in the Assessment of Early Response of Breast Cancer to Neoadjuvant Chemotherapy: Results from ACRIN 6688.
Lale Kostakoglu, Fenghai Duan, +13 authors, ACRIN 668 Investigative Team.
J Nucl Med, 2015 Sep 12; 56(11). PMID: 26359256    Free PMC article.
Prognostic impact of discrepant Ki67 and mitotic index on hormone receptor-positive, HER2-negative breast carcinoma.
L Rossi, E Laas, +6 authors, F Reyal.
Br J Cancer, 2015 Sep 18; 113(7). PMID: 26379080    Free PMC article.
The importance of tissue handling of surgically removed breast cancer for an accurate assessment of the Ki-67 index.
Nobuyuki Arima, Reiki Nishimura, +6 authors, Yasuo Toyozumi.
J Clin Pathol, 2015 Oct 01; 69(3). PMID: 26420767    Free PMC article.
Depletion of mucin in mucin-producing human gastrointestinal carcinoma: Results from in vitro and in vivo studies with bromelain and N-acetylcysteine.
Afshin Amini, Samar Masoumi-Moghaddam, +2 authors, David L Morris.
Oncotarget, 2015 Oct 06; 6(32). PMID: 26436698    Free PMC article.
Quantitative analysis of nuclear shape in oral squamous cell carcinoma is useful for predicting the chemotherapeutic response.
Maki Ogura, Yoichiro Yamamoto, +2 authors, Manabu Fukumoto.
Med Mol Morphol, 2015 Oct 07; 49(2). PMID: 26439725
A methodology for comprehensive breast cancer Ki67 labeling index with intra-tumor heterogeneity appraisal based on hexagonal tiling of digital image analysis data.
Benoit Plancoulaine, Aida Laurinaviciene, +5 authors, Arvydas Laurinavicius.
Virchows Arch, 2015 Oct 21;. PMID: 26481244
Ki-67 and caspase expression in breast carcinoma: does variance in locational sampling exist?
Filinte Deniz, Kaymakci Dilek, +2 authors, Kaya Handan.
Int J Clin Exp Pathol, 2015 Dec 01; 8(9). PMID: 26617854    Free PMC article.
Associations and indications of Ki67 expression with clinicopathological parameters and molecular subtypes in invasive breast cancer: A population-based study.
Jinzhong Sun, Chuang Chen, +9 authors, Shengrong Sun.
Oncol Lett, 2015 Dec 02; 10(3). PMID: 26622743    Free PMC article.
Potent efficacy of metronomic topotecan and pazopanib combination therapy in preclinical models of primary or late stage metastatic triple-negative breast cancer.
Teresa Di Desidero, Ping Xu, +2 authors, Robert S Kerbel.
Oncotarget, 2015 Dec 02; 6(40). PMID: 26623560    Free PMC article.
Biomarkers in Breast Cancer - An Update.
M Schmidt, P A Fasching, M W Beckmann, H Kölbl.
Geburtshilfe Frauenheilkd, 2012 Sep 01; 72(9). PMID: 26640290    Free PMC article.
The Contrasting Role of p16Ink4A Patterns of Expression in Neuroendocrine and Non-Neuroendocrine Lung Tumors: A Comprehensive Analysis with Clinicopathologic and Molecular Correlations.
Nicola Fusco, Elena Guerini-Rocco, +9 authors, Stefano Ferrero.
PLoS One, 2015 Dec 18; 10(12). PMID: 26674347    Free PMC article.
The search for optimal cutoff points for apoptosis and proliferation rate in prognostification of early stage breast cancer patients treated with anthracyclines in adjuvant settings.
Beata Biesaga, Joanna Niemiec, +2 authors, Marek Ziobro.
Tumour Biol, 2015 Dec 22; 37(6). PMID: 26687650
Identification of Risk Factors for Locoregional Recurrence in Breast Cancer Patients with Nodal Stage N0 and N1: Who Could Benefit from Post-Mastectomy Radiotherapy?
Eunjin Jwa, Kyung Hwan Shin, +5 authors, Young Hee Park.
PLoS One, 2015 Dec 23; 10(12). PMID: 26691445    Free PMC article.
Ki-67 is a prognostic marker for hormone receptor positive tumors.
M E Pérez-López, J García-Gómez, +3 authors, T García-Caballero.
Clin Transl Oncol, 2016 Jan 09; 18(10). PMID: 26742937    Free PMC article.
High Proliferation Predicts Pathological Complete Response to Neoadjuvant Chemotherapy in Early Breast Cancer.
Emilio Alba, Ana Lluch, +18 authors, Federico Rojo.
Oncologist, 2016 Jan 21; 21(2). PMID: 26786263    Free PMC article.
Measuring the biological effect of presurgical metformin treatment in endometrial cancer.
V N Sivalingam, S Kitson, +7 authors, E J Crosbie.
Br J Cancer, 2016 Jan 23; 114(3). PMID: 26794276    Free PMC article.
Ki67 expression in breast cancer. Correlation with prognostic markers and clinicopathological parameters in Saudi patients.
Mohamed A Elkablawy, Abdulkader M Albasri, +3 authors, Ahmed S Alhujaily.
Saudi Med J, 2016 Feb 04; 37(2). PMID: 26837394    Free PMC article.
Quantum dots-based double imaging combined with organic dye imaging to establish an automatic computerized method for cancer Ki67 measurement.
Lin-Wei Wang, Ai-Ping Qu, +5 authors, Juan Liu.
Sci Rep, 2016 Feb 04; 6. PMID: 26839163    Free PMC article.
Biomarkers of residual disease after neoadjuvant therapy for breast cancer.
Frederique Penault-Llorca, Nina Radosevic-Robin.
Nat Rev Clin Oncol, 2016 Feb 10; 13(8). PMID: 26856744
Review.
Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline.
Lyndsay N Harris, Nofisat Ismaila, +11 authors, American Society of Clinical Oncology.
J Clin Oncol, 2016 Feb 10; 34(10). PMID: 26858339    Free PMC article.
Highly Cited. Review.
Interobserver Variability of Ki-67 Measurement in Breast Cancer.
Yul Ri Chung, Min Hye Jang, +3 authors, Korean Breast Pathology Ki-67 Study Group.
J Pathol Transl Med, 2016 Feb 16; 50(2). PMID: 26875758    Free PMC article.
Low Concordance between Gene Expression Signatures in ER Positive HER2 Negative Breast Carcinoma Could Impair Their Clinical Application.
Enora Laas, Peter Mallon, +3 authors, Fabien Reyal.
PLoS One, 2016 Feb 20; 11(2). PMID: 26895349    Free PMC article.
Locoregional Recurrence by Tumor Biology in Breast Cancer Patients after Preoperative Chemotherapy and Breast Conservation Treatment.
Eunjin Jwa, Kyung Hwan Shin, +8 authors, Tae Hyun Kim.
Cancer Res Treat, 2016 Oct 19; 48(4). PMID: 26910473    Free PMC article.
Digital image analysis outperforms manual biomarker assessment in breast cancer.
Gustav Stålhammar, Nelson Fuentes Martinez, +9 authors, Johan Hartman.
Mod Pathol, 2016 Feb 27; 29(4). PMID: 26916072
A Comparison of Visual Assessment and Automated Digital Image Analysis of Ki67 Labeling Index in Breast Cancer.
Fangfang Zhong, Rui Bi, +3 authors, Ruohong Shui.
PLoS One, 2016 Mar 02; 11(2). PMID: 26928407    Free PMC article.
The Value of 18F-FDG PET/CT Imaging Combined With Pretherapeutic Ki67 for Early Prediction of Pathologic Response After Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer.
Jurui Luo, Zhirui Zhou, +7 authors, Xiaoli Yu.
Medicine (Baltimore), 2016 Mar 05; 95(8). PMID: 26937935    Free PMC article.
Association Between Insulin Resistance and Luminal B Subtype Breast Cancer in Postmenopausal Women.
Sanggeun Nam, Seho Park, +3 authors, Seung Il Kim.
Medicine (Baltimore), 2016 Mar 06; 95(9). PMID: 26945364    Free PMC article.
Risk Factors Associated with Discordant Ki-67 Levels between Preoperative Biopsy and Postoperative Surgical Specimens in Breast Cancers.
Hyung Sun Kim, Seho Park, +6 authors, Byeong-Woo Park.
PLoS One, 2016 Mar 10; 11(3). PMID: 26954364    Free PMC article.
The Genomic Landscape of Male Breast Cancers.
Salvatore Piscuoglio, Charlotte K Y Ng, +19 authors, Jorge S Reis-Filho.
Clin Cancer Res, 2016 Mar 11; 22(16). PMID: 26960396    Free PMC article.
Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer.
Vidar G Flote, Riyas Vettukattil, +10 authors, Inger Thune.
Lipids Health Dis, 2016 Mar 15; 15. PMID: 26970778    Free PMC article.
The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation.
Tsung-Chieh Lin, Chia-Yi Su, +15 authors, Michael Hsiao.
Elife, 2016 Mar 18; 5. PMID: 26984280    Free PMC article.
Clinical significance of the expression of autophagy-associated marker, beclin 1, in breast cancer patients who received neoadjuvant endocrine therapy.
Takayuki Ueno, Shigehira Saji, +13 authors, Masakazu Toi.
BMC Cancer, 2016 Mar 18; 16. PMID: 26984766    Free PMC article.
Upregulation of E2F8 promotes cell proliferation and tumorigenicity in breast cancer by modulating G1/S phase transition.
Liping Ye, Ling Guo, +8 authors, Huanxin Lin.
Oncotarget, 2016 Mar 19; 7(17). PMID: 26992224    Free PMC article.
Expression of cell cycle markers is predictive of the response to primary systemic therapy of locally advanced breast cancer.
Tímea Tőkés, Anna-Mária Tőkés, +5 authors, Magdolna Dank.
Virchows Arch, 2016 Mar 31; 468(6). PMID: 27026269
Autoantibodies specific to estrogen receptor alpha act as estrogen agonists and their levels correlate with breast cancer cell proliferation.
Angela Maselli, Sara Capoccia, +6 authors, Elena Ortona.
Oncoimmunology, 2016 Apr 09; 5(2). PMID: 27057440    Free PMC article.
Prognostic value of Ki67 and p53 in patients with estrogen receptor-positive and human epidermal growth factor receptor 2-negative breast cancer: Validation of the cut-off value of the Ki67 labeling index as a predictive factor.
Masahiro Ohara, Kazuo Matsuura, +5 authors, Toshiyuki Itamoto.
Mol Clin Oncol, 2016 Apr 14; 4(4). PMID: 27073684    Free PMC article.
Comparison of metastatic neuroendocrine neoplasms to the breast and primary invasive mammary carcinomas with neuroendocrine differentiation.
Sambit K Mohanty, Stacey A Kim, +5 authors, Deepti Dhall.
Mod Pathol, 2016 Apr 30; 29(8). PMID: 27125358
Prognostic value of Ki67 in localized prostate carcinoma: a multi-institutional study of >1000 prostatectomies.
M S Tretiakova, W Wei, +18 authors, J D Brooks.
Prostate Cancer Prostatic Dis, 2016 May 04; 19(3). PMID: 27136741    Free PMC article.
Prognostic and predictive value of Ki-67 in triple-negative breast cancer.
Wei Wang, Jiayi Wu, +9 authors, Li Zhu.
Oncotarget, 2016 May 05; 7(21). PMID: 27145269    Free PMC article.
Optimal Ki67 cut-off for luminal breast cancer prognostic evaluation: a large case series study with a long-term follow-up.
Sara Bustreo, Simona Osella-Abate, +6 authors, Isabella Castellano.
Breast Cancer Res Treat, 2016 May 09; 157(2). PMID: 27155668    Free PMC article.
Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer.
Nikiana Simigdala, Qiong Gao, +8 authors, Lesley-Ann Martin.
Breast Cancer Res, 2016 Jun 02; 18(1). PMID: 27246191    Free PMC article.
Assessing the clinical utility of genomic expression data across human cancers.
Xinsen Xu, Lei Huang, +3 authors, Chang Liu.
Oncotarget, 2016 Jun 21; 7(29). PMID: 27322207    Free PMC article.
Prognostic value of the ubiquitin ligase carboxyl terminus of the Hsc70-interacting protein in postmenopausal breast cancer.
Sasagu Kurozumi, Yuri Yamaguchi, +9 authors, Masafumi Kurosumi.
Cancer Med, 2016 Jun 24; 5(8). PMID: 27334118    Free PMC article.
[Histological grading of breast cancer].
M Christgen, F Länger, H Kreipe.
Pathologe, 2016 Jul 02; 37(4). PMID: 27363708
Review.
Tumor-infiltrating lymphocytes (TILs) are a powerful prognostic marker in patients with triple-negative breast cancer enrolled in the IBCSG phase III randomized clinical trial 22-00.
Giancarlo Pruneri, Kathryn P Gray, +14 authors, Marco Colleoni.
Breast Cancer Res Treat, 2016 Jul 04; 158(2). PMID: 27372069    Free PMC article.
Tumour heterogeneity: principles and practical consequences.
Giorgio Stanta, Stephan Wenzel Jahn, Serena Bonin, Gerald Hoefler.
Virchows Arch, 2016 Jul 15; 469(4). PMID: 27412632
Review.
Value of Ki-67 expression in triple-negative breast cancer before and after neoadjuvant chemotherapy with weekly paclitaxel plus carboplatin.
Ruo-Xi Wang, Sheng Chen, Xi Jin, Zhi-Ming Shao.
Sci Rep, 2016 Jul 19; 6. PMID: 27426056    Free PMC article.
Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer.
Nicola Fusco, Felipe C Geyer, +18 authors, Britta Weigelt.
Mod Pathol, 2016 Oct 28; 29(11). PMID: 27491809    Free PMC article.
Identification of a combined biomarker for malignant transformation in oral submucous fibrosis.
Shadavlonjid Bazarsad, Xianglan Zhang, +4 authors, Jin Kim.
J Oral Pathol Med, 2016 Aug 09; 46(6). PMID: 27497264    Free PMC article.
High-throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium.
Mustapha Abubakar, William J Howat, +40 authors, Montserrat Garcia-Closas.
J Pathol Clin Res, 2016 Aug 09; 2(3). PMID: 27499923    Free PMC article.
Operation with less adjuvant therapy for elderly breast cancer.
Akimitsu Yamada, Kazutaka Narui, +5 authors, Itaru Endo.
J Surg Res, 2016 Aug 28; 204(2). PMID: 27565077    Free PMC article.
The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism.
Ganesan Senthil Kumar, Ezgi Gokhan, +4 authors, Rebecca Page.
Elife, 2016 Aug 31; 5. PMID: 27572260    Free PMC article.
Quantum dot-based molecular imaging of cancer cell growth using a clone formation assay.
Xia-Fei Geng, Min Fang, Shao-Ping Liu, Yan Li.
Mol Med Rep, 2016 Aug 31; 14(4). PMID: 27572664    Free PMC article.
Impact of tissue sampling on accuracy of Ki67 immunohistochemistry evaluation in breast cancer.
Justinas Besusparis, Benoit Plancoulaine, +6 authors, Arvydas Laurinavicius.
Diagn Pathol, 2016 Sep 01; 11(1). PMID: 27576949    Free PMC article.
Long-term outcome in young women with breast cancer: a population-based study.
Hanna Fredholm, Kristina Magnusson, +8 authors, Irma Fredriksson.
Breast Cancer Res Treat, 2016 Sep 15; 160(1). PMID: 27624330    Free PMC article.
Tumor growth rate of invasive breast cancers during wait times for surgery assessed by ultrasonography.
Su Hyun Lee, Young-Seon Kim, +4 authors, Woo Kyung Moon.
Medicine (Baltimore), 2016 Sep 16; 95(37). PMID: 27631256    Free PMC article.
Prognosis of breast cancer molecular subtypes in routine clinical care: A large prospective cohort study.
André Hennigs, Fabian Riedel, +13 authors, Andreas Schneeweiss.
BMC Cancer, 2016 Sep 17; 16(1). PMID: 27634735    Free PMC article.
A prospective comparison of ER, PR, Ki67 and gene expression in paired sequential core biopsies of primary, untreated breast cancer.
Sirwan M Hadad, Lee B Jordan, +5 authors, Alastair M Thompson.
BMC Cancer, 2016 Sep 24; 16(1). PMID: 27658825    Free PMC article.
The proliferation marker Ki67, but not neuroendocrine expression, is an independent factor in the prediction of prognosis of primary prostate cancer patients.
Mariarosa Pascale, Cinzia Aversa, +7 authors, Giorgio Stanta.
Radiol Oncol, 2016 Sep 30; 50(3). PMID: 27679548    Free PMC article.
FOXC1 identifies basal-like breast cancer in a hereditary breast cancer cohort.
Jeff Johnson, Michael Choi, +9 authors, Xiaojiang Cui.
Oncotarget, 2016 Oct 07; 7(46). PMID: 27708239    Free PMC article.
Low Ki67/high ATM protein expression in malignant tumors predicts favorable prognosis in a retrospective study of early stage hormone receptor positive breast cancer.
Xiaolan Feng, Haocheng Li, +9 authors, Alexander Paterson.
Oncotarget, 2016 Oct 16; 7(52). PMID: 27741524    Free PMC article.
Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups.
Mustapha Abubakar, Nick Orr, +38 authors, Montserrat Garcia-Closas.
Breast Cancer Res, 2016 Oct 21; 18(1). PMID: 27756439    Free PMC article.
A novel quantitative immunohistochemistry method for precise protein measurements directly in formalin-fixed, paraffin-embedded specimens: analytical performance measuring HER2.
Kristian Jensen, Rikke Krusenstjerna-Hafstrøm, +2 authors, Helene Derand.
Mod Pathol, 2016 Oct 22; 30(2). PMID: 27767098
The associations between mast cell infiltration, clinical features and molecular types of invasive breast cancer.
Jianfeng Sang, Dandan Yi, +2 authors, Tao Huang.
Oncotarget, 2016 Nov 12; 7(49). PMID: 27835573    Free PMC article.
FISH testing of HER2 immunohistochemistry 1+ invasive breast cancer with unfavorable characteristics.
Stella Petroni, Lucia Caldarola, +4 authors, Giovanni Simone.
Oncol Lett, 2016 Dec 03; 12(5). PMID: 27899970    Free PMC article.
Recent perspectives of breast cancer prognosis and predictive factors.
Su-Sheng Cao, Cun-Tao Lu.
Oncol Lett, 2016 Dec 03; 12(5). PMID: 27900052    Free PMC article.
Ki-67 in endometrial cancer: scoring optimization and prognostic relevance for window studies.
Sarah Kitson, Vanitha N Sivalingam, +11 authors, Emma J Crosbie.
Mod Pathol, 2016 Dec 03; 30(3). PMID: 27910946    Free PMC article.
The genetic landscape of breast carcinomas with neuroendocrine differentiation.
Caterina Marchiò, Felipe C Geyer, +12 authors, Jorge S Reis-Filho.
J Pathol, 2016 Dec 08; 241(3). PMID: 27925203    Free PMC article.
Ki67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).
Matthew J Ellis, Vera J Suman, +28 authors, Kelly Hunt.
J Clin Oncol, 2017 Jan 04; 35(10). PMID: 28045625    Free PMC article.
Highly Cited.
Prognostic significance of Ki67 in Chinese women diagnosed with ER+/HER2- breast cancers by the 2015 St. Gallen consensus classification.
Yue Hu, Ran Gu, +9 authors, Weijuan Jia.
BMC Cancer, 2017 Jan 08; 17(1). PMID: 28061893    Free PMC article.
Correlation between the Ki-67 proliferation index and response to radiation therapy in small cell lung cancer.
Naoya Ishibashi, Toshiya Maebayashi, +3 authors, Shinobu Masuda.
Radiat Oncol, 2017 Jan 15; 12(1). PMID: 28086989    Free PMC article.
Discordance Rate in Estrogen Receptor, Progesterone Receptor, HER2 Status, and Ki67 Index Between Primary Unifocal and Multiple Homogenous Breast Carcinomas and Synchronous Axillary Lymph Node Metastases Have an Impact on Therapeutic Decision.
Rares Georgescu, Monica Boros, +6 authors, Simona Stolnicu.
Appl Immunohistochem Mol Morphol, 2017 Jan 19; 26(8). PMID: 28099174    Free PMC article.
Quantitative proteomics of breast tumors: Tissue quality assessment to clinical biomarkers.
Yi Chen, David Britton, +4 authors, John M Koomen.
Proteomics, 2017 Jan 28; 17(6). PMID: 28127872    Free PMC article.
Ki-67 as a prognostic marker according to breast cancer molecular subtype.
Nahed A Soliman, Shaimaa M Yussif.
Cancer Biol Med, 2017 Feb 06; 13(4). PMID: 28154782    Free PMC article.
Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway.
Jie Liu, Juan Li, +11 authors, Peijun Liu.
Sci Rep, 2017 Feb 09; 7. PMID: 28169360    Free PMC article.
How interacting pathways are regulated by miRNAs in breast cancer subtypes.
Claudia Cava, Antonio Colaprico, +3 authors, Isabella Castiglioni.
BMC Bioinformatics, 2017 Feb 12; 17(Suppl 12). PMID: 28185585    Free PMC article.
A comparison of Ki-67 counting methods in luminal Breast Cancer: The Average Method vs. the Hot Spot Method.
Min Hye Jang, Hyun Jung Kim, +2 authors, So Yeon Park.
PLoS One, 2017 Feb 12; 12(2). PMID: 28187177    Free PMC article.
Transcriptomic dynamics of breast cancer progression in the MMTV-PyMT mouse model.
Ying Cai, Ruben Nogales-Cadenas, +5 authors, Zhengdong D Zhang.
BMC Genomics, 2017 Feb 19; 18(1). PMID: 28212608    Free PMC article.
Ki-67 as a controversial predictive and prognostic marker in breast cancer patients treated with neoadjuvant chemotherapy.
Balázs Ács, Veronika Zámbó, +9 authors, Anna-Mária Tőkés.
Diagn Pathol, 2017 Feb 23; 12(1). PMID: 28222768    Free PMC article.
P53 and Ki-67 as prognostic markers in triple-negative breast cancer patients.
Yunbao Pan, Yufen Yuan, Guoshi Liu, Yongchang Wei.
PLoS One, 2017 Feb 25; 12(2). PMID: 28235003    Free PMC article.
A three-long noncoding RNA signature as a diagnostic biomarker for differentiating between triple-negative and non-triple-negative breast cancers.
Man Liu, Lu-Qi Xing, Yi-Jing Liu.
Medicine (Baltimore), 2017 Mar 02; 96(9). PMID: 28248879    Free PMC article.
Correlation of Molecular Subtypes of Invasive Ductal Carcinoma of Breast with Glucose Metabolism in FDG PET/CT: Based on the Recommendations of the St. Gallen Consensus Meeting 2013.
Sun Seong Lee, Sang Kyun Bae, +5 authors, Seok Mo Lee.
Nucl Med Mol Imaging, 2017 Mar 03; 51(1). PMID: 28250861    Free PMC article.
Reply to 'Comment on 'Nomogram to predict pathologic complete response in HER2-positive breast cancer treated with neoadjuvant systemic therapy''.
Takeo Fujii, Naoto T Ueno.
Br J Cancer, 2017 Mar 16; 116(8). PMID: 28291772    Free PMC article.
Clinical usefulness of the free web-based image analysis application ImmunoRatio for assessment of Ki-67 labelling index in breast cancer.
Min-Kyung Yeo, Hee Eun Kim, +3 authors, Ahwon Lee.
J Clin Pathol, 2017 Mar 17; 70(8). PMID: 28298390    Free PMC article.
Distribution of Iron Oxide Core-Titanium Dioxide Shell Nanoparticles in VX2 Tumor Bearing Rabbits Introduced by Two Different Delivery Modalities.
Tamer Refaat, Derek West, +14 authors, Gayle E Woloschak.
Nanomaterials (Basel), 2016 Jan 01; 6(8). PMID: 28335271    Free PMC article.
Characterisation of male breast cancer: a descriptive biomarker study from a large patient series.
Matthew P Humphries, Sreekumar Sundara Rajan, +18 authors, Valerie Speirs.
Sci Rep, 2017 Mar 30; 7. PMID: 28350011    Free PMC article.
Randomized, placebo-controlled window trial of EGFR, Src, or combined blockade in head and neck cancer.
Julie E Bauman, Umamaheswar Duvvuri, +18 authors, Jennifer R Grandis.
JCI Insight, 2017 Mar 30; 2(6). PMID: 28352657    Free PMC article.
A Microfluidic Immunostaining System Enables Quality Assured and Standardized Immunohistochemical Biomarker Analysis.
Seyong Kwon, Chang Hyun Cho, +2 authors, Je-Kyun Park.
Sci Rep, 2017 Apr 06; 7. PMID: 28378835    Free PMC article.
Reproducibility and Prognostic Potential of Ki-67 Proliferation Index when Comparing Digital-Image Analysis with Standard Semi-Quantitative Evaluation in Breast Cancer.
Balázs Ács, Lilla Madaras, +5 authors, Attila Marcell Szász.
Pathol Oncol Res, 2017 Apr 13; 24(1). PMID: 28401450
Limitations in predicting PAM50 intrinsic subtype and risk of relapse score with Ki67 in estrogen receptor-positive HER2-negative breast cancer.
Aranzazu Fernandez-Martinez, Tomás Pascual, +30 authors, Miguel Martin.
Oncotarget, 2017 Apr 21; 8(13). PMID: 28423537    Free PMC article.
Ki-67 protein expression and tumor associated inflammatory cells (macrophages and mast cells) in canine colorectal carcinoma.
M Woldemeskel, I Hawkins, L Whittington.
BMC Vet Res, 2017 Apr 22; 13(1). PMID: 28427401    Free PMC article.
Peritoneal carcinomatosis of colorectal cancer is characterized by structural and functional reorganization of the tumor microenvironment inducing senescence and proliferation arrest in cancer cells.
Caroline Theresa Seebauer, Stefan Brunner, +6 authors, Rebecca Kesselring.
Oncoimmunology, 2017 Apr 26; 5(12). PMID: 28439450    Free PMC article.
Combined AURKA and H3K9 Methyltransferase Targeting Inhibits Cell Growth By Inducing Mitotic Catastrophe.
Angela Mathison, Ann Salmonson, +10 authors, Gwen Lomberk.
Mol Cancer Res, 2017 Apr 27; 15(8). PMID: 28442587    Free PMC article.
Ki67 expression in invasive breast cancer: the use of tissue microarrays compared with whole tissue sections.
Abir A Muftah, Mohammed A Aleskandarany, +7 authors, Andrew R Green.
Breast Cancer Res Treat, 2017 May 10; 164(2). PMID: 28478613    Free PMC article.
An international reproducibility study validating quantitative determination of ERBB2, ESR1, PGR, and MKI67 mRNA in breast cancer using MammaTyper®.
Zsuzsanna Varga, Annette Lebeau, +18 authors, Giuseppe Viale.
Breast Cancer Res, 2017 May 12; 19(1). PMID: 28490348    Free PMC article.
Quality assurance trials for Ki67 assessment in pathology.
M Raap, S Ließem, +5 authors, H Kreipe.
Virchows Arch, 2017 May 13; 471(4). PMID: 28497316
Power of PgR expression as a prognostic factor for ER-positive/HER2-negative breast cancer patients at intermediate risk classified by the Ki67 labeling index.
Sasagu Kurozumi, Hiroshi Matsumoto, +6 authors, Masafumi Kurosumi.
BMC Cancer, 2017 May 24; 17(1). PMID: 28532429    Free PMC article.
Sex-related differences of urethane and sodium valproate effects on Ki-67 expression in urethane-induced lung tumors of mice.
Donatas Stakišaitis, Raminta Mozūraitė, +4 authors, Angelija Valančiūtė.
Exp Ther Med, 2017 Jun 08; 13(6). PMID: 28587335    Free PMC article.
Does the 1H-NMR plasma metabolome reflect the host-tumor interactions in human breast cancer?
Vincent Richard, Raphaël Conotte, David Mayne, Jean-Marie Colet.
Oncotarget, 2017 Jun 15; 8(30). PMID: 28611296    Free PMC article.
Development of a Ki-67-based clinical trial assay for neoadjuvant endocrine therapy response monitoring in breast cancer.
Rodrigo Goncalves, Katherine DeSchryver, +11 authors, Matthew J Ellis.
Breast Cancer Res Treat, 2017 Jun 15; 165(2). PMID: 28612227    Free PMC article.
Ki-67 Contributes to Normal Cell Cycle Progression and Inactive X Heterochromatin in p21 Checkpoint-Proficient Human Cells.
Xiaoming Sun, Aizhan Bizhanova, +3 authors, Paul D Kaufman.
Mol Cell Biol, 2017 Jun 21; 37(17). PMID: 28630280    Free PMC article.
Inflammation of mammary adipose tissue occurs in overweight and obese patients exhibiting early-stage breast cancer.
Charlotte Vaysse, Jon Lømo, +12 authors, Inger Thune.
NPJ Breast Cancer, 2017 Jun 27; 3. PMID: 28649659    Free PMC article.
Cone-beam Breast Computed Tomography: CT Density Does Not Reflect Proliferation Potential and Receptor Expression of Breast Carcinoma.
Susanne Wienbeck, Uwe Fischer, +4 authors, Alexey Surov.
Transl Oncol, 2017 Jul 01; 10(4). PMID: 28666188    Free PMC article.
Dissecting the Biological Heterogeneity within Hormone Receptor Positive HER2 Negative Breast Cancer by Gene Expression Markers Identifies Indolent Tumors within Late Stage Disease.
Jyothi S Prabhu, Aruna Korlimarla, +14 authors, T S Sridhar.
Transl Oncol, 2017 Jul 14; 10(4). PMID: 28704710    Free PMC article.
Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration.
Samuel C Y Leung, Torsten O Nielsen, +31 authors, Mitch Dowsett.
NPJ Breast Cancer, 2016 May 18; 2. PMID: 28721378    Free PMC article.
Stathmin1 expression is associated with aggressive phenotypes and cancer stem cell marker expression in breast cancer patients.
Sayaka Obayashi, Jun Horiguchi, +10 authors, Hiroyuki Kuwano.
Int J Oncol, 2017 Aug 03; 51(3). PMID: 28766688    Free PMC article.
A predictive analysis of the SP120 and 10D7G2 antibodies for human equilibrative nucleoside transporter 1 (hENT1) in pancreatic ductal adenocarcinoma treated with adjuvant gemcitabine.
Steve E Kalloger, Maziar Riazy, +9 authors, David F Schaeffer.
J Pathol Clin Res, 2017 Aug 05; 3(3). PMID: 28770102    Free PMC article.
IPET study: an FLT-PET window study to assess the activity of the steroid sulfatase inhibitor irosustat in early breast cancer.
Carlo Palmieri, Richard Szydlo, +11 authors, Laura M Kenny.
Breast Cancer Res Treat, 2017 Aug 11; 166(2). PMID: 28795252    Free PMC article.
Whole tumor section quantitative image analysis maximizes between-pathologists' reproducibility for clinical immunohistochemistry-based biomarkers.
Michael Barnes, Chukka Srinivas, +11 authors, Jim Ranger-Moore.
Lab Invest, 2017 Aug 15; 97(12). PMID: 28805805
Over-Expression of Alpha-Enolase as a Prognostic Biomarker in Patients with Pancreatic Cancer.
Lichao Sun, Chunguang Guo, +4 authors, Duxin Sun.
Int J Med Sci, 2017 Aug 22; 14(7). PMID: 28824297    Free PMC article.
Breast cancer subtype discrimination using standardized 4-IHC and digital image analysis.
Marina Gándara-Cortes, Ángel Vázquez-Boquete, +10 authors, Tomás García-Caballero.
Virchows Arch, 2017 Aug 22; 472(2). PMID: 28825136
Ki-67 Expression in Breast Cancer Tissue Microarrays: Assessing Tumor Heterogeneity, Concordance With Full Section, and Scoring Methods.
Thaer Khoury, Gary Zirpoli, +9 authors, Christine B Ambrosone.
Am J Clin Pathol, 2017 Sep 14; 148(2). PMID: 28898983    Free PMC article.
Lack of chemopreventive efficacy of metformin in rodent models of urinary bladder, head and neck, and colon/intestine cancer.
Matthew D Thompson, Ronald A Lubet, +5 authors, Clinton J Grubbs.
Oncol Lett, 2017 Sep 21; 14(3). PMID: 28927103    Free PMC article.
Texture analysis of high-resolution dedicated breast 18 F-FDG PET images correlates with immunohistochemical factors and subtype of breast cancer.
Alexis Moscoso, Álvaro Ruibal, +7 authors, Pablo Aguiar.
Eur J Nucl Med Mol Imaging, 2017 Sep 25; 45(2). PMID: 28936601
Imaging features of breast cancers on digital breast tomosynthesis according to molecular subtype: association with breast cancer detection.
Su Hyun Lee, Jung Min Chang, +4 authors, Woo Kyung Moon.
Br J Radiol, 2017 Sep 25; 90(1080). PMID: 28937263    Free PMC article.
Contrast Enhancement on Cone-Beam Breast-CT for Discrimination of Breast Cancer Immunohistochemical Subtypes.
Johannes Uhlig, Uwe Fischer, +4 authors, Susanne Wienbeck.
Transl Oncol, 2017 Sep 26; 10(6). PMID: 28946110    Free PMC article.
A retrospective prognostic evaluation analysis using the 8th edition of American Joint Committee on Cancer (AJCC) cancer staging system for luminal A breast cancer.
Jingming Ye, Wenjun Wang, +7 authors, Yinhua Liu.
Chin J Cancer Res, 2017 Sep 28; 29(4). PMID: 28947867    Free PMC article.
Revisiting the definition of estrogen receptor positivity in HER2-negative primary breast cancer.
T Fujii, T Kogawa, +10 authors, N T Ueno.
Ann Oncol, 2017 Sep 30; 28(10). PMID: 28961844    Free PMC article.
Mucoadhesive formulation of Bidens pilosa L. (Asteraceae) reduces intestinal injury from 5-fluorouracil-induced mucositis in mice.
Paulo Henrique Marcelino de Ávila, Renato Ivan de Ávila, +8 authors, Marize Campos Valadares.
Toxicol Rep, 2015 Mar 23; 2. PMID: 28962391    Free PMC article.
Comparison of Core Needle Biopsy and Surgical Specimens in Determining Intrinsic Biological Subtypes of Breast Cancer with Immunohistochemistry.
Kiho You, Sungmin Park, +6 authors, Jeong Eon Lee.
J Breast Cancer, 2017 Oct 04; 20(3). PMID: 28970856    Free PMC article.
PAM50 Provides Prognostic Information When Applied to the Lymph Node Metastases of Advanced Breast Cancer Patients.
Nicholas P Tobin, Arian Lundberg, +13 authors, TEX Trialists Group.
Clin Cancer Res, 2017 Oct 04; 23(23). PMID: 28972041    Free PMC article.
Gene Expression Signatures and Immunohistochemical Subtypes Add Prognostic Value to Each Other in Breast Cancer Cohorts.
Arian Lundberg, Linda S Lindström, +8 authors, Nicholas P Tobin.
Clin Cancer Res, 2017 Oct 04; 23(24). PMID: 28972043    Free PMC article.
The value of phosphohistone H3 as a proliferation marker for evaluating invasive breast cancers: A comparative study with Ki67.
Ji-Ye Kim, Hyang Sook Jeong, +4 authors, Ja Seung Koo.
Oncotarget, 2017 Oct 17; 8(39). PMID: 29029412    Free PMC article.
On expert curation and scalability: UniProtKB/Swiss-Prot as a case study.
Sylvain Poux, Cecilia N Arighi, +8 authors, The UniProt Consortium.
Bioinformatics, 2017 Oct 17; 33(21). PMID: 29036270    Free PMC article.
Cat Mammary Tumors: Genetic Models for the Human Counterpart.
Filomena Adega, Ana Borges, Raquel Chaves.
Vet Sci, 2016 Aug 16; 3(3). PMID: 29056725    Free PMC article.
Review.
Canine invasive mammary carcinomas as models of human breast cancer. Part 2: immunophenotypes and prognostic significance.
Jérôme Abadie, Frédérique Nguyen, +8 authors, Mario Campone.
Breast Cancer Res Treat, 2017 Oct 25; 167(2). PMID: 29063312    Free PMC article.
Persistent homology index as a robust quantitative measure of immunohistochemical scoring.
Akihiro Takiyama, Takashi Teramoto, +2 authors, Shinya Tanaka.
Sci Rep, 2017 Oct 27; 7(1). PMID: 29070862    Free PMC article.
A Microdevice Platform Recapitulating Hypoxic Tumor Microenvironments.
Yuta Ando, Hoang P Ta, +3 authors, Keyue Shen.
Sci Rep, 2017 Nov 11; 7(1). PMID: 29123197    Free PMC article.
Prognostic value of PAM50 and risk of recurrence score in patients with early-stage breast cancer with long-term follow-up.
Hege O Ohnstad, Elin Borgen, +11 authors, Bjørn Naume.
Breast Cancer Res, 2017 Nov 16; 19(1). PMID: 29137653    Free PMC article.
A tissue microRNA signature that predicts the prognosis of breast cancer in young women.
Ai Hironaka-Mitsuhashi, Juntaro Matsuzaki, +10 authors, Takahiro Ochiya.
PLoS One, 2017 Nov 16; 12(11). PMID: 29141042    Free PMC article.
Ki67 Proliferation Index as a Histopathological Predictive and Prognostic Parameter of Oral Mucosal Melanoma in Patients without Distant Metastases.
Xuhui Ma, Yunteng Wu, +4 authors, Guoxin Ren.
J Cancer, 2017 Nov 21; 8(18). PMID: 29151970    Free PMC article.
Combined Ki67 and ERCC1 for prognosis in non-keratinizing nasopharyngeal carcinoma underwent chemoradiotherapy.
Ying Lu, Haixin Huang, +4 authors, Rensheng Wang.
Oncotarget, 2017 Nov 29; 8(51). PMID: 29179456    Free PMC article.
Intra-tumor heterogeneity in breast cancer has limited impact on transcriptomic-based molecular profiling.
Govindasamy-Muralidharan Karthik, Mattias Rantalainen, +9 authors, Johan Hartman.
BMC Cancer, 2017 Dec 01; 17(1). PMID: 29187174    Free PMC article.
Alterations in three biomarkers (estrogen receptor, progesterone receptor and human epidermal growth factor 2) and the Ki67 index between primary and metastatic breast cancer lesions.
Kimihito Fujii, Rie Watanabe, +6 authors, Takashi Fukutomi.
Biomed Rep, 2017 Dec 01; 7(6). PMID: 29188058    Free PMC article.
Large-scale DNA organization is a prognostic marker of breast cancer survival.
Martial Guillaud, Qian Ye, +5 authors, Mira Keyes.
Med Oncol, 2017 Dec 08; 35(1). PMID: 29214466
Concomitant activation of ETS-like transcription factor-1 and Death Receptor-5 via extracellular signal-regulated kinase in withaferin A-mediated inhibition of hepatocarcinogenesis in mice.
Panjamurthy Kuppusamy, Arumugam Nagalingam, +2 authors, Dipali Sharma.
Sci Rep, 2017 Dec 22; 7(1). PMID: 29263422    Free PMC article.
Biomarkers in breast cancer: A consensus statement by the Spanish Society of Medical Oncology and the Spanish Society of Pathology.
R Colomer, I Aranda-López, +7 authors, J Palacios-Calvo.
Clin Transl Oncol, 2017 Dec 24; 20(7). PMID: 29273958    Free PMC article.
Review.
Building Up a High-throughput Screening Platform to Assess the Heterogeneity of HER2 Gene Amplification in Breast Cancers.
Giulia Ercoli, Gianluca Lopez, +7 authors, Nicola Fusco.
J Vis Exp, 2017 Dec 30; (130). PMID: 29286417    Free PMC article.
Heterogeneity of PD-L1 expression in primary tumors and paired lymph node metastases of triple negative breast cancer.
Ming Li, Anqi Li, +4 authors, Wentao Yang.
BMC Cancer, 2018 Jan 03; 18(1). PMID: 29291717    Free PMC article.
The prognostic value of Ki67 in ovarian high-grade serous carcinoma: an 11-year cohort study of Chinese patients.
Ming Chen, Shuzhong Yao, +3 authors, Mian He.
Oncotarget, 2018 Jan 04; 8(64). PMID: 29296209    Free PMC article.
The use of automated Ki67 analysis to predict Oncotype DX risk-of-recurrence categories in early-stage breast cancer.
Satbir Singh Thakur, Haocheng Li, +5 authors, Hua Yang.
PLoS One, 2018 Jan 06; 13(1). PMID: 29304138    Free PMC article.
Clinical and pathological factors influencing survival in a large cohort of triple-negative breast cancer patients.
Silvana Anna Maria Urru, Silvano Gallus, +25 authors, Sandra Orrù.
BMC Cancer, 2018 Jan 10; 18(1). PMID: 29310602    Free PMC article.
Ki-67: more than a proliferation marker.
Xiaoming Sun, Paul D Kaufman.
Chromosoma, 2018 Jan 13; 127(2). PMID: 29322240    Free PMC article.
Highly Cited. Review.
Fundamentals of siRNA and miRNA therapeutics and a review of targeted nanoparticle delivery systems in breast cancer.
Tamkin Ahmadzada, Glen Reid, David R McKenzie.
Biophys Rev, 2018 Jan 13; 10(1). PMID: 29327101    Free PMC article.
Review.
Digital image analysis of Ki67 proliferation index in breast cancer using virtual dual staining on whole tissue sections: clinical validation and inter-platform agreement.
Timco Koopman, Henk J Buikema, +2 authors, Bert van der Vegt.
Breast Cancer Res Treat, 2018 Jan 20; 169(1). PMID: 29349710    Free PMC article.
Can Histological Grade and Mitotic Index Replace Ki67 to Determine Luminal Breast Cancer Subtypes?
David Oddó, Dahiana Pulgar, +11 authors, César Sánchez.
Asian Pac J Cancer Prev, 2018 Jan 28; 19(1). PMID: 29373911    Free PMC article.
Combined effect of obesity and diabetes on early breast cancer outcome: a prospective observational study.
Giuseppe Buono, Anna Crispo, +16 authors, Grazia Arpino.
Oncotarget, 2018 Feb 01; 8(70). PMID: 29383194    Free PMC article.
Inhibition of breast cancer cell survival by Xanthohumol via modulation of the Notch signaling pathway in vivo and in vitro.
Zhihong Sun, Cheng Zhou, +8 authors, Qin Wang.
Oncol Lett, 2018 Feb 10; 15(1). PMID: 29422966    Free PMC article.
Assessment of the predictive role of pretreatment Ki-67 and Ki-67 changes in breast cancer patients receiving neoadjuvant chemotherapy according to the molecular classification: a retrospective study of 1010 patients.
Rui Chen, Yin Ye, +9 authors, Shengchun Liu.
Breast Cancer Res Treat, 2018 Feb 27; 170(1). PMID: 29480449    Free PMC article.
Ki67 Changes Identify Worse Outcomes in Residual Breast Cancer Tumors After Neoadjuvant Chemotherapy.
Paula Cabrera-Galeana, Wendy Muñoz-Montaño, +9 authors, Oscar Arrieta.
Oncologist, 2018 Mar 02; 23(6). PMID: 29490940    Free PMC article.
Aberrant Ki-67 expression through 3'UTR alternative polyadenylation in breast cancers.
Hong Yan, Rui Tian, +3 authors, Jie He.
FEBS Open Bio, 2018 Mar 08; 8(3). PMID: 29511610    Free PMC article.
Analysis of membranous Ki-67 staining in breast cancer and surrounding breast epithelium.
Gábor Cserni.
Virchows Arch, 2018 Mar 30; 473(2). PMID: 29594352
Nuclear Insulin-Like Growth Factor Binding Protein-3 As a Biomarker in Triple-Negative Breast Cancer Xenograft Tumors: Effect of Targeted Therapy and Comparison With Chemotherapy.
Sohel M Julovi, Janet L Martin, Robert C Baxter.
Front Endocrinol (Lausanne), 2018 Apr 07; 9. PMID: 29623068    Free PMC article.
Prognostic value of Ki-67 according to age in patients with triple-negative breast cancer.
V Zenzola, M A Cabezas-Quintario, +4 authors, J García-Foncillas.
Clin Transl Oncol, 2018 Apr 20; 20(11). PMID: 29671222
Prospective Randomized Biomarker Study of Metformin and Lifestyle Intervention for Prevention in Obese Women at Increased Risk for Endometrial Cancer.
Melinda S Yates, Adriana M Coletta, +12 authors, Karen Lu.
Cancer Prev Res (Phila), 2018 May 03; 11(8). PMID: 29716897    Free PMC article.
Practical consensus recommendations regarding the management of hormone receptor positive early breast cancer in elderly women.
Govind Babu, A Goel, +8 authors, Purvish M Parikh.
South Asian J Cancer, 2018 May 04; 7(2). PMID: 29721478    Free PMC article.
Pre-surgical trial of the AKT inhibitor MK-2206 in patients with operable invasive breast cancer: a New York Cancer Consortium trial.
K Kalinsky, J A Sparano, +17 authors, D L Hershman.
Clin Transl Oncol, 2018 May 08; 20(11). PMID: 29736694    Free PMC article.
Conventional Pathology Versus Gene Signatures for Assessing Luminal A and B Type Breast Cancers: Results of a Prospective Cohort Study.
Julia E C van Steenhoven, Anne Kuijer, +12 authors, Thijs van Dalen.
Genes (Basel), 2018 May 19; 9(5). PMID: 29772837    Free PMC article.
Predicting initial margin status in breast cancer patients during breast-conserving surgery.
Zihao Pan, Liling Zhu, +5 authors, Kai Chen.
Onco Targets Ther, 2018 May 22; 11. PMID: 29780255    Free PMC article.
Is Ki67 prognostic for aggressive prostate cancer? A multicenter real-world study.
Joseph J Fantony, Lauren E Howard, +5 authors, Stephen J Freedland.
Biomark Med, 2018 Jun 16; 12(7). PMID: 29902938    Free PMC article.
Overexpression of topoisomerase II alpha protein is a factor for poor prognosis in patients with luminal B breast cancer.
Hideo Shigematsu, Shinji Ozaki, +7 authors, Kiyomi Taniyama.
Oncotarget, 2018 Jun 22; 9(42). PMID: 29928479    Free PMC article.
Expression of Gastric Markers Is Associated with Malignant Potential of Nonampullary Duodenal Adenocarcinoma.
Chihiro Minatsuki, Nobutake Yamamichi, +16 authors, Kazuhiko Koike.
Dig Dis Sci, 2018 Jun 30; 63(10). PMID: 29956011
ERα-mediated cell cycle progression is an important requisite for CDK4/6 inhibitor response in HR+ breast cancer.
Karineh Petrossian, Noriko Kanaya, +14 authors, Shiuan Chen.
Oncotarget, 2018 Jul 03; 9(45). PMID: 29963233    Free PMC article.
Correlation between the dynamic contrast-enhanced MRI features and prognostic factors in breast cancer: A retrospective case-control study.
Weijing Tao, Chunhong Hu, +2 authors, Yaning Zhu.
Medicine (Baltimore), 2018 Jul 12; 97(28). PMID: 29995825    Free PMC article.
Prognostic significance of Ki67 expression and the derived neutrophil-lymphocyte ratio in nasopharyngeal carcinoma.
Liang Zhao, Haojun Chen, +2 authors, Qin Lin.
Cancer Manag Res, 2018 Jul 18; 10. PMID: 30013398    Free PMC article.
Patient advocate involvement in the design and conduct of breast cancer clinical trials requiring the collection of multiple biopsies.
Leona M Batten, Indrani Subarna Bhattacharya, +10 authors, Judith M Bliss.
Res Involv Engagem, 2018 Jul 22; 4. PMID: 30026963    Free PMC article.
Predictive Factors of Eribulin Activity in Metastatic Breast Cancer Patients.
Rita De Sanctis, Elisa Agostinetto, +7 authors, Armando Santoro.
Oncology, 2018 Jul 24; 94 Suppl 1. PMID: 30036884    Free PMC article.
Characterization of FGD5 Expression in Primary Breast Cancers and Lymph Node Metastases.
Marit Valla, Patricia G Mjønes, +7 authors, Anna M Bofin.
J Histochem Cytochem, 2018 Jul 28; 66(11). PMID: 30052477    Free PMC article.
Expression of PD-1 on CD4+ Tumor-Infiltrating Lymphocytes in Tumor Microenvironment Associated with Pathological Characteristics of Breast Cancer.
Yan-Jie Zhao, Jian Zhang, +8 authors, Qing-Kun Song.
J Immunol Res, 2018 Aug 03; 2018. PMID: 30069490    Free PMC article.
APOBEC3B gene expression as a novel predictive factor for pathological complete response to neoadjuvant chemotherapy in breast cancer.
Yoshitaka Fujiki, Yutaka Yamamoto, +5 authors, Hirotaka Iwase.
Oncotarget, 2018 Aug 11; 9(55). PMID: 30093965    Free PMC article.
Practical Consequences Resulting from the Analysis of a 21-Multigene Array in the Interdisciplinary Conference of a Breast Cancer Center.
Hans-Ullrich Voelker, Lea Frey, Annette Strehl, Michael Weigel.
Int J Breast Cancer, 2018 Aug 17; 2018. PMID: 30112216    Free PMC article.
Comparison of central laboratory assessments of ER, PR, HER2, and Ki67 by IHC/FISH and the corresponding mRNAs (ESR1, PGR, ERBB2, and MKi67) by RT-qPCR on an automated, broadly deployed diagnostic platform.
Natalie C Wu, Wendy Wong, +17 authors, Michael F Press.
Breast Cancer Res Treat, 2018 Aug 19; 172(2). PMID: 30120700    Free PMC article.
Ki 67 assessment in breast cancer in an Egyptian population: a comparative study between manual assessment on optical microscopy and digital quantitative assessment.
Essam Ayad, Ahmed Soliman, +3 authors, Youhong Dong.
Diagn Pathol, 2018 Aug 30; 13(1). PMID: 30153851    Free PMC article.
Relationship between the Ki67 index and its area based approximation in breast cancer.
Muhammad Khalid Khan Niazi, Caglar Senaras, +3 authors, Metin N Gurcan.
BMC Cancer, 2018 Sep 05; 18(1). PMID: 30176814    Free PMC article.
MiR-876-5p modulates head and neck squamous cell carcinoma metastasis and invasion by targeting vimentin.
Yibo Dong, Yang Zheng, +8 authors, Xiaomeng Song.
Cancer Cell Int, 2018 Sep 06; 18. PMID: 30181714    Free PMC article.
PET imaging of chemokine receptor CXCR4 in patients with primary and recurrent breast carcinoma.
Tibor Vag, Katja Steiger, +7 authors, Markus Schwaiger.
EJNMMI Res, 2018 Sep 08; 8(1). PMID: 30191351    Free PMC article.
Comparison of Oncoplastic Breast-Conserving Surgery and Breast-Conserving Surgery Alone: A Meta-Analysis.
Jun-Ying Chen, Yi-Jie Huang, +2 authors, Kun Wang.
J Breast Cancer, 2018 Oct 03; 21(3). PMID: 30275861    Free PMC article.
[Standardized determination of tumor-infiltrating lymphocytes in breast cancer : A prognostic marker for histological diagnosis].
C Denkert, S Loibl, +2 authors, F Klauschen.
Pathologe, 2018 Oct 18; 39(6). PMID: 30327858
Review.
Higher Ki67 expression in fibroblast like cells at invasive front indicates better clinical outcomes in oral squamous cell carcinoma patients.
Yue Jing, Yan Yang, +6 authors, Yanhong Ni.
Biosci Rep, 2018 Oct 21; 38(6). PMID: 30341240    Free PMC article.
RollFISH achieves robust quantification of single-molecule RNA biomarkers in paraffin-embedded tumor tissue samples.
Chenglin Wu, Michele Simonetti, +8 authors, Mats Nilsson.
Commun Biol, 2018 Dec 05; 1. PMID: 30511022    Free PMC article.
Diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) mapping as a quantitative imaging biomarker for prediction of immunohistochemical receptor status, proliferation rate, and molecular subtypes of breast cancer.
Joao V Horvat, Blanca Bernard-Davila, +11 authors, Katja Pinker.
J Magn Reson Imaging, 2019 Feb 28; 50(3). PMID: 30811717    Free PMC article.
The role of Ki-67 in Asian triple negative breast cancers: a novel combinatory panel approach.
An Sen Tan, Joe Poe Sheng Yeong, +8 authors, Puay Hoon Tan.
Virchows Arch, 2019 Aug 14; 475(6). PMID: 31407032
Ki-67 (30-9) scoring and differentiation of Luminal A- and Luminal B-like breast cancer subtypes.
Giuseppe Viale, Amy E Hanlon Newell, +5 authors, Patrick Maisonneuve.
Breast Cancer Res Treat, 2019 Aug 20; 178(2). PMID: 31422497    Free PMC article.
Proliferation in Postmenopausal Endometrial Polyps-A Potential for Malignant Transformation.
Lina Adomaitienė, Rūta Nadišauskienė, +4 authors, Mourad W Seif.
Medicina (Kaunas), 2019 Aug 31; 55(9). PMID: 31466367    Free PMC article.
Generation of in situ sequencing based OncoMaps to spatially resolve gene expression profiles of diagnostic and prognostic markers in breast cancer.
Jessica Svedlund, Carina Strell, +5 authors, Mats Nilsson.
EBioMedicine, 2019 Sep 19; 48. PMID: 31526717    Free PMC article.
Comparing docosahexaenoic acid (DHA) concomitant with neoadjuvant chemotherapy versus neoadjuvant chemotherapy alone in the treatment of breast cancer (DHA WIN): protocol of a double-blind, phase II, randomised controlled trial.
Marnie Newell, John R Mackey, +19 authors, Catherine Field.
BMJ Open, 2019 Sep 19; 9(9). PMID: 31530611    Free PMC article.
Decrease in the Ki67 index during neoadjuvant chemotherapy predicts favorable relapse-free survival in patients with locally advanced breast cancer.
Chunfa Chen, Yuling Zhang, +3 authors, Guojun Zhang.
Cancer Biol Med, 2019 Oct 01; 16(3). PMID: 31565486    Free PMC article.
IHC Color Histograms for Unsupervised Ki67 Proliferation Index Calculation.
Rokshana S Geread, Peter Morreale, +4 authors, April Khademi.
Front Bioeng Biotechnol, 2019 Oct 22; 7. PMID: 31632956    Free PMC article.
External quality assessment (EQA) program for the immunohistochemical detection of ER, PR and Ki-67 in breast cancer: results of an interlaboratory reproducibility ring study in China.
Tianjie Pu, Ruohong Shui, +6 authors, China Anticancer Association Professional Committee of Tumour Pathology.
BMC Cancer, 2019 Oct 24; 19(1). PMID: 31640622    Free PMC article.
Expression of FGD3 gene as prognostic factor in young breast cancer patients.
Irene Renda, Simonetta Bianchi, +4 authors, Tommaso Susini.
Sci Rep, 2019 Oct 28; 9(1). PMID: 31645624    Free PMC article.
Prognostic Value of Ki-67 in Patients With Resected Triple-Negative Breast Cancer: A Meta-Analysis.
Qiang Wu, Guangzhi Ma, +4 authors, Qinghua Zhou.
Front Oncol, 2019 Nov 05; 9. PMID: 31681601    Free PMC article.
Systematic Review.
VGLL4 interacts with STAT3 to function as a tumor suppressor in triple-negative breast cancer.
Hongming Song, Qifeng Luo, +6 authors, Lin Fang.
Exp Mol Med, 2019 Nov 22; 51(11). PMID: 31748508    Free PMC article.
Dual time point 18F-fluorodeoxyglucose positron emission tomography/computed tomography fusion imaging (18F-FDG PET/CT) in primary breast cancer.
Yoji Yamagishi, Tomomi Koiwai, +8 authors, Hitoshi Tsuda.
BMC Cancer, 2019 Nov 30; 19(1). PMID: 31775675    Free PMC article.
Quantitative assessment of Ki67 expression in correlation with various breast cancer characteristics and survival rate; cross sectional study.
Ayad Ahmad Mohammed.
Ann Med Surg (Lond), 2019 Dec 04; 48. PMID: 31788239    Free PMC article.
Matrix metalloproteases and TIMPs as prognostic biomarkers in breast cancer patients treated with radiotherapy: A pilot study.
María Auxiliadora Olivares-Urbano, Carmen Griñán-Lisón, +8 authors, María Isabel Núñez.
J Cell Mol Med, 2019 Oct 01; 24(1). PMID: 31568637    Free PMC article.
Impact of aromatase inhibitor treatment on global gene expression and its association with antiproliferative response in ER+ breast cancer in postmenopausal patients.
Qiong Gao, Elena López-Knowles, +16 authors, POETIC Trial Management Group and Trialists.
Breast Cancer Res, 2020 Jan 02; 22(1). PMID: 31892336    Free PMC article.
Prevalence of Molecular Subtypes of Breast Cancer: A Single Institutional Experience of 2062 Patients.
Prakash Pandit, Roshankumar Patil, +3 authors, Rajnish Nagarkar.
Eur J Breast Health, 2020 Jan 09; 16(1). PMID: 31912012    Free PMC article.
Neoadjuvant Metformin Added to Systemic Therapy Decreases the Proliferative Capacity of Residual Breast Cancer.
Eugeni Lopez-Bonet, Maria Buxó, +24 authors, Javier A Menendez.
J Clin Med, 2019 Dec 15; 8(12). PMID: 31835708    Free PMC article.
Clinicopathologic characteristics of HER2-positive pure mucinous breast carcinoma: a systematic investigation into an unusual tumor.
Ya-Ni Wei, Shan Liu, +3 authors, Bing Wei.
Int J Clin Exp Pathol, 2020 Jan 15; 12(5). PMID: 31933985    Free PMC article.
Soft tissue sarcoma: DWI and DCE-MRI parameters correlate with Ki-67 labeling index.
Ji Hyun Lee, Young Cheol Yoon, +2 authors, Hyun Su Kim.
Eur Radiol, 2019 Oct 21; 30(2). PMID: 31630234
The discordance pattern of molecular sub-types between primary and metastatic sites in Chinese breast cancer patients.
Gaoda Ju, Rongxuan Zhu, +9 authors, Hongxia Wang.
Int J Clin Exp Pathol, 2020 Jan 18; 11(12). PMID: 31949681    Free PMC article.
Standardised Ki-67 proliferation index assessment in early-stage laryngeal squamous cell carcinoma in relation to local control and survival after primary radiotherapy.
Emiel Kop, Geertruida H de Bock, +5 authors, Bert van der Vegt.
Clin Otolaryngol, 2019 Sep 29; 45(1). PMID: 31561282    Free PMC article.
Early metabolic response of breast cancer to neoadjuvant endocrine therapy: comparison to morphological and pathological response.
Sarah Boughdad, Laurence Champion, +5 authors, Jean-Louis Alberini.
Cancer Imaging, 2020 Jan 30; 20(1). PMID: 31992361    Free PMC article.
Assessment of Ki67 expression for breast cancer subtype classification and prognosis in the Nurses' Health Study.
Megan A Healey, Kelly A Hirko, +6 authors, Aditi Hazra.
Breast Cancer Res Treat, 2017 Aug 10; 166(2). PMID: 28791482    Free PMC article.
Microcystic adnexal carcinoma: report of rare cases.
Lei Zhang, Xiaofeng Huang, Ting Zhou, Hongbao Cao.
Biosci Rep, 2020 Jan 09; 40(1). PMID: 31912868    Free PMC article.
Analysis of the molecular subtypes of preoperative core needle biopsy and surgical specimens in invasive breast cancer.
Ye Sul Jeong, Jun Kang, +3 authors, Ahwon Lee.
J Pathol Transl Med, 2019 Nov 14; 54(1). PMID: 31718121    Free PMC article.
Integration of Ki-67 index into AJCC 2018 staging provides additional prognostic information in breast tumours candidate for genomic profiling.
Elena Vissio, Jasna Metovic, +7 authors, Isabella Castellano.
Br J Cancer, 2019 Nov 30; 122(3). PMID: 31780778    Free PMC article.
Double-positive in triple-negative? How significant is basal cytokeratin expression in breast cancer?
Anusree Majumder, Rajat Jagani, Atoshi Basu.
Med J Armed Forces India, 2020 Feb 06; 76(1). PMID: 32020971    Free PMC article.
Clinicopathologic analysis of 722 breast cancer patients who met the inclusion criteria of the TAILORx trial.
Hong-Yu Xiang, Yin-Hua Liu, +7 authors, Qian Liu.
Chin Med J (Engl), 2019 Dec 07; 132(24). PMID: 31809316    Free PMC article.
Downregulation of Siah1 promotes colorectal cancer cell proliferation and migration by regulating AKT and YAP ubiquitylation and proteasome degradation.
Zhiyuan Xiao, Zhigang Wei, +11 authors, Hongli Jiao.
Cancer Cell Int, 2020 Feb 23; 20. PMID: 32082080    Free PMC article.
Assessment of Ki67 in Breast Cancer: A Comparison Between the Eye-10 Method, Stepwise Counting Strategy, and International System of Ki67 Evaluation.
Maryam Kadivar, Fatemeh Aram.
Iran J Pathol, 2020 Feb 26; 15(1). PMID: 32095144    Free PMC article.
miRNA expression profiling of hereditary breast tumors from BRCA1- and BRCA2-germline mutation carriers in Brazil.
Danielle Pessôa-Pereira, Adriane Feijó Evangelista, +10 authors, Márcia Maria Chiquitelli Marques.
BMC Cancer, 2020 Feb 24; 20(1). PMID: 32087690    Free PMC article.
Three-dimensional imaging and quantitative analysis in CLARITY processed breast cancer tissues.
Yi Chen, Qi Shen, +3 authors, Laurie J Goodman.
Sci Rep, 2019 Apr 06; 9(1). PMID: 30948791    Free PMC article.
Proliferation Tumour Marker Network (PTM-NET) for the identification of tumour region in Ki67 stained breast cancer whole slide images.
Jesuchristopher Joseph, Martine P Roudier, +8 authors, William J Howat.
Sci Rep, 2019 Sep 08; 9(1). PMID: 31492872    Free PMC article.
Ki-67 assessment in early breast cancer: SAKK28/12 validation study on the IBCSG VIII and IBCSG IX cohort.
Zsuzsanna Varga, Qiyu Li, +7 authors, Thomas Ruhstaller.
Sci Rep, 2019 Sep 21; 9(1). PMID: 31537812    Free PMC article.
Changes in the Ki-67 labeling index between primary breast cancer and metachronous metastatic axillary lymph node: A retrospective observational study.
Naoya Ishibashi, Haruna Nishimaki, +5 authors, Masahiro Okada.
Thorac Cancer, 2018 Oct 31; 10(1). PMID: 30375185    Free PMC article.
Association Between Postpartum Breast Cancer Diagnosis and Metastasis and the Clinical Features Underlying Risk.
Erica T Goddard, Solange Bassale, +8 authors, Virginia F Borges.
JAMA Netw Open, 2019 Jan 16; 2(1). PMID: 30646210    Free PMC article.
Prognostic Characterization of Higher-Grade Meningiomas: A Histopathological Score to Predict Progression and Outcome.
Luca Bertero, Giulia Dalla Dea, +15 authors, Paola Cassoni.
J Neuropathol Exp Neurol, 2019 Jan 29; 78(3). PMID: 30689922    Free PMC article.
Practical approaches to automated digital image analysis of Ki-67 labeling index in 997 breast carcinomas and causes of discordance with visual assessment.
Ah-Young Kwon, Ha Young Park, +7 authors, Eun Yoon Cho.
PLoS One, 2019 Feb 21; 14(2). PMID: 30785924    Free PMC article.
Combined quantitative measures of ER, PR, HER2, and KI67 provide more prognostic information than categorical combinations in luminal breast cancer.
Mustapha Abubakar, Jonine Figueroa, +8 authors, Paul D Pharoah.
Mod Pathol, 2019 Apr 13; 32(9). PMID: 30976105    Free PMC article.
A simple immunohistochemical bio-profile incorporating Bcl2 curbs those cases of invasive breast carcinoma for which an Oncotype Dx characterization is needed.
Claudio Ceccarelli, Antonio De Leo, +5 authors, Donatella Santini.
PLoS One, 2019 Jun 04; 14(6). PMID: 31158261    Free PMC article.
Oral metronomic vinorelbine combined with endocrine therapy in hormone receptor-positive HER2-negative breast cancer: SOLTI-1501 VENTANA window of opportunity trial.
Barbara Adamo, Meritxell Bellet, +16 authors, Aleix Prat.
Breast Cancer Res, 2019 Sep 20; 21(1). PMID: 31533777    Free PMC article.
Ki-67, an elusive marker in the prognosis of breast cancer.
Neelam Sood.
Indian J Med Res, 2019 Nov 14; 150(3). PMID: 31719290    Free PMC article.
Diagnostic ability of real-time quantitative polymerase chain reaction versus immunohistochemistry for Ki-67 assessment in breast cancer: An Indian perspective.
Anurag Mehta, Dushyant Kumar, +5 authors, Ajit Panaych.
Indian J Med Res, 2019 Nov 14; 150(3). PMID: 31719296    Free PMC article.
Prognostic value of IMP3 immunohistochemical expression in triple negative breast cancer.
Nikoleta Sjekloča, Snjezana Tomić, +4 authors, Marina Maras-Šimunić.
Medicine (Baltimore), 2020 Feb 13; 99(7). PMID: 32049813    Free PMC article.
Combined Erlotinib and PF-03084014 treatment contributes to synthetic lethality in head and neck squamous cell carcinoma.
Yang Zheng, Zhao Wang, +7 authors, Xiaomeng Song.
Cell Prolif, 2017 Dec 13; 51(3). PMID: 29232766    Free PMC article.
Refinement of breast cancer molecular classification by miRNA expression profiles.
Rolf Søkilde, Helena Persson, +11 authors, Carlos Rovira.
BMC Genomics, 2019 Jun 19; 20(1). PMID: 31208318    Free PMC article.
Predictive factors of 5-year relapse-free survival in HR+/HER2- breast cancer patients treated with neoadjuvant endocrine therapy: pooled analysis of two phase 2 trials.
Florence Lerebours, Marina Pulido, +17 authors, Nathalie Quenel-Tueux.
Br J Cancer, 2020 Feb 01; 122(6). PMID: 32001832    Free PMC article.
Quality assurance guidance for scoring and reporting for pathologists and laboratories undertaking clinical trial work.
Max Robinson, Jacqueline James, +12 authors, UK National Cancer Research Institute (NCRI) Cellular-Molecular Pathology (CM-Path) clinical trials working group.
J Pathol Clin Res, 2018 Nov 09; 5(2). PMID: 30407751    Free PMC article.
Synergistic anti-cancer activity of CDK4/6 inhibitor palbociclib and dual mTOR kinase inhibitor MLN0128 in pRb-expressing ER-negative breast cancer.
Takuro Yamamoto, Noriko Kanaya, George Somlo, Shiuan Chen.
Breast Cancer Res Treat, 2019 Jan 05; 174(3). PMID: 30607633    Free PMC article.
Identification and validation of key genes with prognostic value in non-small-cell lung cancer via integrated bioinformatics analysis.
Li Wang, Jialin Qu, +4 authors, Xiaochun Zhang.
Thorac Cancer, 2020 Feb 15; 11(4). PMID: 32059076    Free PMC article.
Axillary nodal involvement by primary tumor features in early breast cancer: an analysis of 2600 patients.
M C De Santis, E La Rocca, +13 authors, S Di Cosimo.
Clin Transl Oncol, 2019 Aug 03; 22(5). PMID: 31372896
Aromatase Inhibitors as Adjuvant Treatment for ER/PgR Positive Stage I Endometrial Carcinoma: A Retrospective Cohort Study.
Laura Paleari, Mariangela Rutigliani, +3 authors, Andrea Decensi.
Int J Mol Sci, 2020 Mar 27; 21(6). PMID: 32210157    Free PMC article.
Biocompatibility of common implantable sensor materials in a tumor xenograft model.
Mark E Gray, James Meehan, +8 authors, David Argyle.
J Biomed Mater Res B Appl Biomater, 2018 Oct 28; 107(5). PMID: 30367816    Free PMC article.
Early detection of changes in phospholipid metabolism during neoadjuvant chemotherapy in breast cancer patients using phosphorus magnetic resonance spectroscopy at 7T.
Erwin Krikken, Wybe J M van der Kemp, +5 authors, Jannie P Wijnen.
NMR Biomed, 2019 Mar 30; 32(6). PMID: 30924571    Free PMC article.
Neoadjuvant exemestane or exemestane plus docetaxel and cyclophosphamide tailored by clinicopathological response to 12 weeks' exemestane exposure in patients with estrogen receptor-positive breast cancer: A multicenter, open-label, phase II study.
Nobuaki Sato, Norikazu Masuda, +9 authors, Masakazu Toi.
Cancer Med, 2019 Jul 31; 8(12). PMID: 31361400    Free PMC article.
Reciprocal expression of Annexin A6 and RasGRF2 discriminates rapidly growing from invasive triple negative breast cancer subsets.
Olga Y Korolkova, Sarrah E Widatalla, +10 authors, Amos M Sakwe.
PLoS One, 2020 Apr 17; 15(4). PMID: 32298357    Free PMC article.
Gene expression profiling revealed MCM3 to be a better marker than Ki67 in prognosis of invasive ductal breast carcinoma patients.
Yue Zhao, Yimin Wang, +3 authors, Dongwei Zhang.
Clin Exp Med, 2020 Jan 26; 20(2). PMID: 31980982
Cutoff of 25% for Ki67 expression is a good classification tool for prognosis in colorectal cancer in the AJCC‑8 stratification.
Guojun Tong, Guiyang Zhang, +4 authors, Xuting Xu.
Oncol Rep, 2020 Apr 24; 43(4). PMID: 32323802    Free PMC article.
Imaging features of triple-negative breast cancers according to androgen receptor status.
Rosalind P Candelaria, Beatriz E Adrada, +13 authors, Wei Tse Yang.
Eur J Radiol, 2019 Apr 22; 114. PMID: 31005169    Free PMC article.
[Immunoncology and tumor infiltrating lymphocytes-new strategies for therapy and diagnosis of breast cancer].
Carsten Denkert.
Pathologe, 2020 Apr 05; 41(3). PMID: 32246201
Review.
Digital quantification of KI-67 in breast cancer.
María Del Rosario Taco Sanchez, Teresa Soler-Monsó, +7 authors, Xavier Matias-Guiu.
Virchows Arch, 2018 Nov 23; 474(2). PMID: 30465110
Breast Cancer 18F-ISO-1 Uptake as a Marker of Proliferation Status.
Elizabeth S McDonald, Robert K Doot, +14 authors, David A Mankoff.
J Nucl Med, 2019 Dec 15; 61(5). PMID: 31836680    Free PMC article.
Effect of Ki-67 Expression Levels and Histological Grade on Breast Cancer Early Relapse in Patients with Different Immunohistochemical-based Subtypes.
Qin Liang, Ding Ma, Run-Fang Gao, Ke-Da Yu.
Sci Rep, 2020 May 08; 10(1). PMID: 32376868    Free PMC article.
Molecular natural history of breast cancer: Leveraging transcriptomics to predict breast cancer progression and aggressiveness.
Daniel J Cook, Jonatan Kallus, Rebecka Jörnsten, Jens Nielsen.
Cancer Med, 2020 Mar 25; 9(10). PMID: 32207233    Free PMC article.
Tumour-infiltrating lymphocytes and response to neoadjuvant letrozole in patients with early oestrogen receptor-positive breast cancer: analysis from a nationwide phase II DBCG trial.
Signe Korsgaard Skriver, Maj-Britt Jensen, +2 authors, Anne-Vibeke Laenkholm.
Breast Cancer Res, 2020 May 16; 22(1). PMID: 32410705    Free PMC article.
Expression of E cadherin and Ki 67: Emerging Prognostic Markers in Triple-Negative Breast Cancer.
Jayaprakash Shetty, Chandrika Rao.
Indian J Surg Oncol, 2019 Jun 07; 10(2). PMID: 31168266    Free PMC article.
Dynamic FDG-PET/CT in the Initial Staging of Primary Breast Cancer: Clinicopathological Correlations.
Kornélia Kajáry, Zsolt Lengyel, +3 authors, Tímea Tőkés.
Pathol Oncol Res, 2019 Apr 04; 26(2). PMID: 30941738    Free PMC article.
Automated quantitative analysis of Ki-67 staining and HE images recognition and registration based on whole tissue sections in breast carcinoma.
Min Feng, Yang Deng, +10 authors, Hong Bu.
Diagn Pathol, 2020 May 31; 15(1). PMID: 32471471    Free PMC article.
Ki-67 response-guided preoperative chemotherapy for HER2-positive breast cancer: results of a randomised Phase 2 study.
Hirofumi Mukai, Takeshi Yamaguchi, +14 authors, Yukari Uemura.
Br J Cancer, 2020 Apr 03; 122(12). PMID: 32238920    Free PMC article.
Prognostic impact of ACTN4 gene copy number alteration in hormone receptor-positive, HER2-negative, node-negative invasive breast carcinoma.
Teppei Sugano, Masayuki Yoshida, +7 authors, Tesshi Yamada.
Br J Cancer, 2020 Apr 09; 122(12). PMID: 32265507    Free PMC article.
Evidence-based guidelines for managing patients with primary ER+ HER2- breast cancer deferred from surgery due to the COVID-19 pandemic.
Mitch Dowsett, Matthew J Ellis, +16 authors, Nadia Harbeck.
NPJ Breast Cancer, 2020 Jun 19; 6. PMID: 32550266    Free PMC article.
Prognostic and Clinicopathological Correlations of Cell Cycle Marker Expressions before and after the Primary Systemic Therapy of Breast Cancer.
Tímea Tőkés, Anna-Mária Tőkés, +6 authors, Magdolna Dank.
Pathol Oncol Res, 2019 Aug 26; 26(3). PMID: 31446607    Free PMC article.
Distribution of the 21-Gene Breast Recurrence Score in Patients with Primary Breast Cancer in Germany.
Vincent P Walter, Florin-Andrei Taran, +6 authors, Andreas Daniel Hartkopf.
Geburtshilfe Frauenheilkd, 2020 Jun 23; 80(6). PMID: 32565552    Free PMC article.
Assessment of the Predictive Role of Serum Lipid Profiles in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy.
Fanli Qu, Rui Chen, +6 authors, Shengchun Liu.
J Breast Cancer, 2020 Jul 01; 23(3). PMID: 32595987    Free PMC article.
Independent Prognostic Value of Intratumoral Heterogeneity and Immune Response Features by Automated Digital Immunohistochemistry Analysis in Early Hormone Receptor-Positive Breast Carcinoma.
Dovile Zilenaite, Allan Rasmusson, +5 authors, Arvydas Laurinavicius.
Front Oncol, 2020 Jul 03; 10. PMID: 32612954    Free PMC article.
Utility of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Fusion Imaging for Prediction of Metastasis to Sentinel and Nonsentinel Nodes in Patients with Clinically Node-Negative Breast Cancer.
Yoji Yamagishi, Tamio Yamasaki, +9 authors, Hitoshi Tsuda.
Ann Surg Oncol, 2020 Mar 04; 27(8). PMID: 32124121    Free PMC article.
Prognostic values of YTHDF1 regulated negatively by mir-3436 in Glioma.
Chenyang Xu, Bingjian Yuan, +2 authors, Song Li.
J Cell Mol Med, 2020 May 26; 24(13). PMID: 32449290    Free PMC article.
Association among T2 signal intensity, necrosis, ADC and Ki-67 in estrogen receptor-positive and HER2-negative invasive ductal carcinoma.
Soo-Yeon Kim, Eun-Kyung Kim, +4 authors, Min Jung Kim.
Magn Reson Imaging, 2018 Sep 03; 54. PMID: 30172938    Free PMC article.
Prognostic potential of automated Ki67 evaluation in breast cancer: different hot spot definitions versus true global score.
Stephanie Robertson, Balazs Acs, Michael Lippert, Johan Hartman.
Breast Cancer Res Treat, 2020 Jun 24; 183(1). PMID: 32572716    Free PMC article.
Risk stratification in luminal-type breast cancer: Comparison of Ki-67 with EndoPredict test results.
Aurelia Noske, Sophie-Isabelle Anders, +6 authors, Evelyn Klein.
Breast, 2019 Dec 02; 49. PMID: 31786414    Free PMC article.
An interobserver reproducibility analysis of size-set semiautomatic counting for Ki67 assessment in breast cancer.
Yi-Xing Wang, Yuan-Yuan Wang, +9 authors, Ju-Lun Yang.
Breast, 2020 Jan 09; 49. PMID: 31911370    Free PMC article.
Do YOU know the Ki-67 index of your breast cancer patients? Knowledge of your institution's Ki-67 index distribution and its robustness is essential for decision-making in early breast cancer.
Angela Fischer Maranta, Simon Broder, +4 authors, Thomas Ruhstaller.
Breast, 2020 Apr 18; 51. PMID: 32302928    Free PMC article.
Avoidance and Period-Shortening of Neoadjuvant Chemotherapy Against Triple-Negative Breast Cancer in Stages I and II: Importance of Ki-67 Labeling Index and the Recognition of Apocrine-Type Lesions.
Koichi Kubouchi, Kyosuke Shimada, Takamichi Yokoe, Yutaka Tsutsumi.
Technol Cancer Res Treat, 2020 Jul 18; 19. PMID: 32677589    Free PMC article.
Sequential immunohistochemistry and virtual image reconstruction using a single slide for quantitative KI67 measurement in breast cancer.
Garazi Serna, Sara Simonetti, +10 authors, Paolo Nuciforo.
Breast, 2020 Jul 25; 53. PMID: 32707454    Free PMC article.
Coexpression Analysis of the EZH2 Gene Using The Cancer Genome Atlas and Oncomine Databases Identifies Coexpressed Genes Involved in Biological Networks in Breast Cancer, Glioblastoma, and Prostate Cancer.
Jin Zhu, Lu Jin, +5 authors, Dongrong Yang.
Med Sci Monit, 2020 Jul 01; 26. PMID: 32595202    Free PMC article.
Prognostic value of neutrophil-to-lymphocyte ratio in human epidermal growth factor receptor 2-negative breast cancer patients who received neoadjuvant chemotherapy.
Soong June Bae, Yoon Jin Cha, +10 authors, Joon Jeong.
Sci Rep, 2020 Aug 06; 10(1). PMID: 32753659    Free PMC article.
The healthcare value of the Magee Decision Algorithm™: use of Magee Equations™ and mitosis score to safely forgo molecular testing in breast cancer.
Rohit Bhargava, Beth Z Clark, +2 authors, David J Dabbs.
Mod Pathol, 2020 Mar 24; 33(8). PMID: 32203092    Free PMC article.
CLDN6-mediates SB431542 action through MMPs to regulate the invasion, migration, and EMT of breast cancer cells.
Xuesong Li, Hongmei Li, +5 authors, Liping Wang.
Int J Clin Exp Pathol, 2020 Aug 13; 13(7). PMID: 32782677    Free PMC article.
Enhancement of Antitumor Efficacy of Paclitaxel-Loaded PEGylated Liposomes by N,N-Dimethyl Tertiary Amino Moiety in Pancreatic Cancer.
Yang Chen, Li Wang, +6 authors, Bo-Le Tian.
Drug Des Devel Ther, 2020 Aug 18; 14. PMID: 32801636    Free PMC article.
Digital Image Analysis of Ki-67 Stained Tissue Microarrays and Recurrence in Tamoxifen-Treated Breast Cancer Patients.
Nina Gran Egeland, Kristin Jonsdottir, +7 authors, Emiel A M Janssen.
Clin Epidemiol, 2020 Aug 18; 12. PMID: 32801916    Free PMC article.
Hyaluronan Metabolism is Associated with DNA Repair Genes in Breast and Colorectal Cancer. Screening of Potential Progression Markers Using qPCR.
Ina Sevic, Fiorella Mercedes Spinelli, +7 authors, Laura Alaniz.
Biomedicines, 2020 Jul 03; 8(7). PMID: 32610620    Free PMC article.
Phosphorylated ribosomal S6 (p-rpS6) as a post-treatment indicator of HER2 signalling targeted drug resistance.
Gloria Yang-Kolodji, Shannon M Mumenthaler, +2 authors, Debu Tripathy.
Biomarkers, 2015 Sep 04; 20(5). PMID: 26329528    Free PMC article.
Ki67 and PR in Patients Treated with CDK4/6 Inhibitors: A Real-World Experience.
Michela Palleschi, Roberta Maltoni, +16 authors, Sara Bravaccini.
Diagnostics (Basel), 2020 Aug 14; 10(8). PMID: 32784518    Free PMC article.
Prognostic values of GPNMB identified by mining TCGA database and STAD microenvironment.
Kunhou Yao, Lunshou Wei, +4 authors, Song Li.
Aging (Albany NY), 2020 Aug 25; 12(16). PMID: 32833670    Free PMC article.
High Expression of FGD3, a Putative Regulator of Cell Morphology and Motility, Is Prognostic of Favorable Outcome in Multiple Cancers.
Scooter Willis, Yuliang Sun, +20 authors, Brian Leyland-Jones.
JCO Precis Oncol, 2017 Oct 13; 1. PMID: 32913979    Free PMC article.
Clinical Value of RNA Sequencing-Based Classifiers for Prediction of the Five Conventional Breast Cancer Biomarkers: A Report From the Population-Based Multicenter Sweden Cancerome Analysis Network-Breast Initiative.
Christian Brueffer, Johan Vallon-Christersson, +13 authors, Lao H Saal.
JCO Precis Oncol, 2018 Mar 09; 2. PMID: 32913985    Free PMC article.
Genomic Instability and TP53 Genomic Alterations Associate With Poor Antiproliferative Response and Intrinsic Resistance to Aromatase Inhibitor Treatment.
Eugene F Schuster, Pascal Gellert, +9 authors, POETIC Trial Management Group and Trialists.
JCO Precis Oncol, 2019 Jun 12; 3. PMID: 32914010    Free PMC article.
Radiogenomics Analysis of Intratumor Heterogeneity in a Patient With High-Grade Serous Ovarian Cancer.
Britta Weigelt, Hebert Alberto Vargas, +16 authors, Evis Sala.
JCO Precis Oncol, 2019 Jun 06; 3. PMID: 32914032    Free PMC article.
[Prognosis factors analysis of patients with malignant solitary pulmonary nodules].
Y Q Ouyang, L F Ni, X M Liu.
Beijing Da Xue Xue Bao Yi Xue Ban, 2020 Feb 20; 52(1). PMID: 32071480    Free PMC article.
Potent Cell-Cycle Inhibition and Upregulation of Immune Response with Abemaciclib and Anastrozole in neoMONARCH, Phase II Neoadjuvant Study in HR+/HER2- Breast Cancer.
Sara A Hurvitz, Miguel Martin, +16 authors, Dennis J Slamon.
Clin Cancer Res, 2019 Oct 17; 26(3). PMID: 31615937    Free PMC article.
Membrane mesothelin expression positivity is associated with poor clinical outcome of luminal-type breast cancer.
Takafumi Suzuki, Yoji Yamagishi, +14 authors, Hitoshi Tsuda.
Oncol Lett, 2020 Sep 22; 20(5). PMID: 32952662    Free PMC article.
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
Xin Jiang, Yanwei Du, +6 authors, Hongyu Jiang.
Dose Response, 2019 Jan 10; 16(4). PMID: 30622447    Free PMC article.
Primary systemic therapy in HER2-positive operable breast cancer using trastuzumab and chemotherapy: efficacy data, cardiotoxicity and long-term follow-up in 142 patients diagnosed from 2005 to 2016 at a single institution.
Silvia Antolín, Benigno Acea, +7 authors, Lourdes Calvo.
Breast Cancer (Dove Med Press), 2019 Jan 16; 11. PMID: 30643452    Free PMC article.
Metachronous bilateral triple-negative breast cancer associated with neurofibromatosis type 1: A case report.
Yoji Yamagishi, Takahiro Einama, +7 authors, Hitoshi Tsuda.
Oncol Lett, 2019 Mar 12; 17(3). PMID: 30854057    Free PMC article.
Clinical validation of Ki67 by quantitative reverse transcription-polymerase chain reaction (RT-PCR) in HR+/HER2- early breast cancer.
Weiqi Gao, Jiayi Wu, +4 authors, Ou Huang.
J Cancer, 2019 Mar 12; 10(5). PMID: 30854118    Free PMC article.
Tumor-Associated Macrophages as Potential Prognostic Biomarkers of Invasive Breast Cancer.
Hasong Jeong, Ilseon Hwang, +2 authors, Sun Young Kwon.
J Breast Cancer, 2019 Apr 04; 22(1). PMID: 30941232    Free PMC article.
Highly Cited.
A Pathology-Based Combined Model to Identify PAM50 Non-luminal Intrinsic Disease in Hormone Receptor-Positive HER2-Negative Breast Cancer.
Tomás Pascual, Miguel Martin, +21 authors, Aleix Prat.
Front Oncol, 2019 May 21; 9. PMID: 31106144    Free PMC article.
Should a Multigene Signature be Used in all Luminal Early Breast Cancers.
Nawale Hajjaji, Yves Marie Robin, Jacques Bonneterre.
Front Oncol, 2019 Jun 20; 9. PMID: 31214499    Free PMC article.
Mammaglobin-A, VEGFR3, and Ki67 in Human Breast Cancer Pathology and Five Year Survival.
Elizabeth Baker, Naomi Whiteoak, +3 authors, Pudupalayam Bhaskar.
Breast Cancer (Auckl), 2019 Jul 03; 13. PMID: 31263371    Free PMC article.
Mismatch Repair Protein Loss as a Prognostic and Predictive Biomarker in Breast Cancers Regardless of Microsatellite Instability.
Nicola Fusco, Gianluca Lopez, +13 authors, Silvano Bosari.
JNCI Cancer Spectr, 2019 Jul 31; 2(4). PMID: 31360876    Free PMC article.
Association of ki67 and tumor marker p53 in locally advanced breast cancer patients and evaluation of response to neoadjuvant chemotherapy: a survey in South Iran.
Dena Firouzabadi, Alireza Rezvani, Amirreza Dehghanian, Laleh Mahmoudi.
Cancer Manag Res, 2019 Aug 03; 11. PMID: 31372050    Free PMC article.
Neoadjuvant endocrine therapy: A potential strategy for ER-positive breast cancer.
Li-Tong Yao, Mo-Zhi Wang, +5 authors, Ying-Ying Xu.
World J Clin Cases, 2019 Aug 20; 7(15). PMID: 31423426    Free PMC article.
Review.
Factors influencing agreement of breast cancer luminal molecular subtype by Ki67 labeling index between core needle biopsy and surgical resection specimens.
Kristina A Tendl-Schulz, Fabian Rössler, +15 authors, Zsuzsanna Bago-Horvath.
Virchows Arch, 2020 May 10; 477(4). PMID: 32383007    Free PMC article.
Rivaroxaban compared to no treatment in ER-negative stage I-III early breast cancer patients (the TIP Trial): study protocol for a phase II preoperative window-of-opportunity study design randomised controlled trial.
John Castle, Emma Blower, +8 authors, Cliona C Kirwan.
Trials, 2020 Aug 29; 21(1). PMID: 32854772    Free PMC article.
Breast cancer subtypes: implications for the treatment and survival of patients in Africa-a prospective cohort study from Mozambique.
Mariana Brandão, Assucena Guisseve, +13 authors, Nuno Lunet.
ESMO Open, 2020 Oct 07; 5(5). PMID: 33020218    Free PMC article.
The role of cyclin D1 and Ki-67 in the development and prognostication of thin melanoma.
Corina Kaufmann, Werner Kempf, +8 authors, Peter Koelblinger.
Histopathology, 2020 May 07; 77(3). PMID: 32374893    Free PMC article.
Kank1 and Ki67 expression are associated with poor prognosis in human pulmonary adenocarcinoma.
Xiao-Chun Shen, Chong-Jun Ni, +2 authors, Guo-Jian Gu.
Int J Clin Exp Pathol, 2020 Oct 13; 13(9). PMID: 33042336    Free PMC article.
Comparison between AJCC 8th prognostic stage and UICC anatomical stage in patients with primary breast cancer: a single institutional retrospective study.
Ryo Tanaka, Yoji Yamagishi, +8 authors, Hitoshi Tsuda.
Breast Cancer, 2020 Jun 05; 27(6). PMID: 32495291    Free PMC article.
Expression and significance of Her2 and Ki-67 in gastric adenocarcinoma without distant metastasis: a cohort study.
Zhijian Wei, Lei Huang, Xinyue Zhang, Aman Xu.
BMC Gastroenterol, 2020 Oct 17; 20(1). PMID: 33059614    Free PMC article.
STARD4 promotes breast cancer cell malignancy.
Min Zhang, Zhen Xiang, +7 authors, Wei-Bing Zhou.
Oncol Rep, 2020 Oct 31; 44(6). PMID: 33125124    Free PMC article.
Prognostic Value of Ki67 in Patients with Stage 1-2 Endometrial Cancer: Validation of the Cut-off Value of Ki67 as a Predictive Factor.
Peng Jiang, Mingzhu Jia, +5 authors, Zhuoying Hu.
Onco Targets Ther, 2020 Nov 06; 13. PMID: 33149602    Free PMC article.
Contralateral parenchymal enhancement on breast MRI before and during neoadjuvant endocrine therapy in relation to the preoperative endocrine prognostic index.
Max A A Ragusi, Claudette E Loo, +5 authors, Kenneth G A Gilhuijs.
Eur Radiol, 2020 Jul 22; 30(12). PMID: 32691100    Free PMC article.
MYC Targets Scores Are Associated with Cancer Aggressiveness and Poor Survival in ER-Positive Primary and Metastatic Breast Cancer.
Amy Schulze, Masanori Oshi, Itaru Endo, Kazuaki Takabe.
Int J Mol Sci, 2020 Nov 05; 21(21). PMID: 33143224    Free PMC article.
Hexokinase II in breast carcinoma: a potent prognostic factor associated with hypoxia-inducible factor-1α and Ki-67.
Akiko Sato-Tadano, Takashi Suzuki, +7 authors, Noriaki Ohuchi.
Cancer Sci, 2013 Jul 23; 104(10). PMID: 23869589    Free PMC article.
Interobserver concordance of Ki67 labeling index in breast cancer: Japan Breast Cancer Research Group Ki67 ring study.
Yoshiki Mikami, Takayuki Ueno, +6 authors, Hironobu Sasano.
Cancer Sci, 2013 Aug 03; 104(11). PMID: 23905924    Free PMC article.
A comparative study between Ki67 positive versus Ki67 negative females with breast cancer: Cross sectional study.
Mowafak Masoud Bahaddin.
Ann Med Surg (Lond), 2020 Nov 17; 60. PMID: 33194179    Free PMC article.
Immunohistochemical Ki67 labeling index has similar proliferation predictive power to various gene signatures in breast cancer.
Naoki Niikura, Takayuki Iwamoto, +9 authors, Yutaka Tokuda.
Cancer Sci, 2012 Apr 28; 103(8). PMID: 22537114    Free PMC article.
A narrative review of digital pathology and artificial intelligence: focusing on lung cancer.
Taro Sakamoto, Tomoi Furukawa, +8 authors, Junya Fukuoka.
Transl Lung Cancer Res, 2020 Nov 20; 9(5). PMID: 33209648    Free PMC article.
Review.
Histological Aspects and Quantitative Assessment of Ki67 as Prognostic Factors in Breast Cancer Patients: Result from a Single-Center, Cross Sectional Study.
Irina Niță, Cornelia Nițipir, +6 authors, Loredana Sabina Cornelia Manolescu.
Medicina (Kaunas), 2020 Nov 14; 56(11). PMID: 33182401    Free PMC article.
Reducing chemotherapy use in clinically high-risk, genomically low-risk pN0 and pN1 early breast cancer patients: five-year data from the prospective, randomised phase 3 West German Study Group (WSG) PlanB trial.
Ulrike Nitz, Oleg Gluz, +18 authors, Nadia Harbeck.
Breast Cancer Res Treat, 2017 Jul 01; 165(3). PMID: 28664507    Free PMC article.
The impact of obesity and bariatric surgery on circulating and tissue biomarkers of endometrial cancer risk.
Michelle L MacKintosh, Abigail E Derbyshire, +12 authors, Emma J Crosbie.
Int J Cancer, 2018 Oct 06; 144(3). PMID: 30289975    Free PMC article.
[Ki67: biological intertumor variance versus variance of assay].
H Kreipe.
Pathologe, 2018 Oct 18; 39(Suppl 2). PMID: 30327857
Review.
Ki-67 Prognostic Value in Different Histological Grades of Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma
Amer Takkem, Charif Barakat, +4 authors, Mohammad Yaman Seirawan.
Asian Pac J Cancer Prev, 2018 Nov 30; 19(11). PMID: 30486632    Free PMC article.
Carboxypeptidase A4 accumulation is associated with an aggressive phenotype and poor prognosis in triple-negative breast cancer.
Tadashi Handa, Ayaka Katayama, +11 authors, Tetsunari Oyama.
Int J Oncol, 2019 Jan 11; 54(3). PMID: 30628666    Free PMC article.
Re-testing of predictive biomarkers on surgical breast cancer specimens is clinically relevant.
Stephanie Robertson, Caroline Rönnlund, Jana de Boniface, Johan Hartman.
Breast Cancer Res Treat, 2019 Jan 20; 174(3). PMID: 30659433    Free PMC article.
Immunohistochemical Evaluation of Ki-67 and Comparison with Clinicopathologic Factors in Breast Carcinomas
Nguiessan Alphonse Aman, Brahima Doukoure, +5 authors, Ahoua Benjamin Effi.
Asian Pac J Cancer Prev, 2019 Jan 27; 20(1). PMID: 30678383    Free PMC article.
[Update of the German S3 breast cancer guideline : What is new for pathologists?]
A Lebeau, C Denkert, +2 authors, A Wöckel.
Pathologe, 2019 Mar 09; 40(2). PMID: 30847505
Optimized Ki-67 staining in murine cells: a tool to determine cell proliferation.
C Graefe, L Eichhorn, +9 authors, C K Weisheit.
Mol Biol Rep, 2019 May 17; 46(4). PMID: 31093875
Clinicopathological Features and Disease Outcome in Breast Cancer Patients with Hormonal Receptor Discordance between Core Needle Biopsy and Following Surgical Sample.
Siji Zhu, Jiayi Wu, +7 authors, Kunwei Shen.
Ann Surg Oncol, 2019 May 31; 26(9). PMID: 31144143    Free PMC article.
PROGNOSTIC IMPACT OF LOW ESTROGEN AND PROGESTERONE POSITIVITY IN LUMINAL B (HER2 NEGATIVE) BREAST CANCER.
Jasmina Rajc, Irena Fröhlich, +2 authors, Josipa Flam.
Acta Clin Croat, 2019 Jun 07; 57(3). PMID: 31168174    Free PMC article.
Healthcare use and costs in early breast cancer: a patient-level data analysis according to stage and breast cancer subtype.
Mariana Brandão, Samantha Morais, +7 authors, Nuno Lunet.
ESMO Open, 2020 Nov 26; 5(6). PMID: 33234552    Free PMC article.
Mammographic tumour appearance is related to clinicopathological factors and surrogate molecular breast cancer subtype.
Li Sturesdotter, Malte Sandsveden, +3 authors, Hanna Sartor.
Sci Rep, 2020 Dec 02; 10(1). PMID: 33257731    Free PMC article.
A negative binomial regression model for risk estimation of 0-2 axillary lymph node metastases in breast cancer patients.
De Zeng, Hao-Yu Lin, +4 authors, Chun-Fa Chen.
Sci Rep, 2020 Dec 16; 10(1). PMID: 33318591    Free PMC article.
Solid-type adenoid cystic carcinoma of the breast, a distinct molecular entity enriched in NOTCH and CREBBP mutations.
Julie Massé, Caroline Truntzer, +11 authors, Gaëtan MacGrogan.
Mod Pathol, 2019 Dec 21; 33(6). PMID: 31857685
Ki67 Immunohistochemistry Quantification in Breast Carcinoma: A Comparison of Visual Estimation, Counting, and ImmunoRatio.
Eunice J van den Berg, Raquel Duarte, +2 authors, Reena Mohanlal.
Appl Immunohistochem Mol Morphol, 2020 Jun 27; 29(2). PMID: 32590453    Free PMC article.
Pharmacokinetic Analysis of Dynamic Contrast-Enhanced Magnetic Resonance Imaging at 7T for Breast Cancer Diagnosis and Characterization.
R Elena Ochoa-Albiztegui, Varadan Sevilimedu, +6 authors, Katja Pinker.
Cancers (Basel), 2020 Dec 18; 12(12). PMID: 33327532    Free PMC article.
Mass Spectrometry-Based Omics for the Characterization of Triple-Negative Breast Cancer Bio-Signature.
Ioana-Ecaterina Pralea, Radu-Cristian Moldovan, +2 authors, Cristina-Adela Iuga.
J Pers Med, 2020 Dec 17; 10(4). PMID: 33322818    Free PMC article.
Review.
Breast Cancer Organoids Model Patient-Specific Response to Drug Treatment.
Elena Campaner, Alessandro Zannini, +8 authors, Giannino Del Sal.
Cancers (Basel), 2020 Dec 30; 12(12). PMID: 33371412    Free PMC article.
Multi-color clonal tracking reveals intra-stage proliferative heterogeneity during mammary tumor progression.
Stefanie Tiede, Ravi Kiran Reddy Kalathur, +8 authors, Gerhard Christofori.
Oncogene, 2020 Oct 14; 40(1). PMID: 33046799
piNET-An Automated Proliferation Index Calculator Framework for Ki67 Breast Cancer Images.
Rokshana Stephny Geread, Abishika Sivanandarajah, +4 authors, April Khademi.
Cancers (Basel), 2020 Dec 31; 13(1). PMID: 33375043    Free PMC article.
Tumor vasculature-targeted 10B delivery by an Annexin A1-binding peptide boosts effects of boron neutron capture therapy.
Tohru Yoneyama, Shingo Hatakeyama, +9 authors, Chikara Ohyama.
BMC Cancer, 2021 Jan 16; 21(1). PMID: 33446132    Free PMC article.
A clinical validation study of MammaPrint in hormone receptor-positive breast cancer from the Austrian Breast and Colorectal Cancer Study Group 8 (ABCSG-8) biomarker cohort.
P Dubsky, L Van't Veer, +13 authors, M Filipits.
ESMO Open, 2021 Jan 06; 6(1). PMID: 33399073    Free PMC article.
The Presence of an In Situ Component on Pre-Treatment Biopsy Is Not Associated with Response to Neoadjuvant Chemotherapy for Breast Cancer.
Julie Labrosse, Charlotte Morel, +6 authors, Anne-Sophie Hamy.
Cancers (Basel), 2021 Jan 14; 13(2). PMID: 33435265    Free PMC article.
Standardized pathology report for breast cancer.
Soo Youn Cho, So Yeon Park, +10 authors, Hye Kyoung Yoon.
J Pathol Transl Med, 2021 Jan 20; 55(1). PMID: 33461287    Free PMC article.
Review.
Analysis of CK5/6 and EGFR and Its Effect on Prognosis of Triple Negative Breast Cancer.
Zhen Wang, Lei Liu, +4 authors, Sheng Zhang.
Front Oncol, 2021 Feb 09; 10. PMID: 33552956    Free PMC article.
Association of PET-based estradiol-challenge test for breast cancer progesterone receptors with response to endocrine therapy.
Farrokh Dehdashti, Ningying Wu, +3 authors, Barry A Siegel.
Nat Commun, 2021 Feb 04; 12(1). PMID: 33531464    Free PMC article.
Concordance of the molecular subtype classification between core needle biopsy and surgical specimen in primary breast cancer.
M Pölcher, M Braun, +6 authors, O Stoetzer.
Arch Gynecol Obstet, 2021 Feb 16;. PMID: 33585986
A Phenomic Perspective on Factors Influencing Breast Cancer Treatment: Integrating Aging and Lifestyle in Blood and Tissue Biomarker Profiling.
Ainhoa Arana Echarri, Mark Beresford, +6 authors, James E Turner.
Front Immunol, 2021 Feb 19; 11. PMID: 33597950    Free PMC article.
Review.
Rare common bile duct metastasis of breast cancer: A case report and literature review.
Jie Tang, Guang-Xi Zhao, Shuang-Shuang Deng, Ming Xu.
World J Gastrointest Oncol, 2021 Mar 02; 13(2). PMID: 33643530    Free PMC article.
Standardized Pathology Report for Breast Cancer.
Soo Youn Cho, So Yeon Park, +10 authors, Hye Kyoung Yoon.
J Breast Cancer, 2021 Feb 27; 24(1). PMID: 33634617    Free PMC article.
Review.
Molecular Biomarkers for Contemporary Therapies in Hormone Receptor-Positive Breast Cancer.
Allegra Freelander, Lauren J Brown, +4 authors, Elgene Lim.
Genes (Basel), 2021 Mar 07; 12(2). PMID: 33671468    Free PMC article.
Review.
Prognostic role of serum thymidine kinase 1 kinetics during neoadjuvant chemotherapy for early breast cancer.
A Matikas, K Wang, +18 authors, T Foukakis.
ESMO Open, 2021 Mar 14; 6(2). PMID: 33714010    Free PMC article.
Better overall survival in patients who achieve pathological complete response after neoadjuvant chemotherapy for breast cancer in a Chilean public hospital.
Francisco Acevedo, Militza Petric, +14 authors, Raúl Martinez.
Ecancermedicalscience, 2021 Mar 30; 15. PMID: 33777178    Free PMC article.
Association of the imaging characteristics of desmoplasia on digital breast tomosynthesis and the Ki-67 proliferation index in invasive breast cancer.
Kristina Samaržija, Zoran Jurjević.
Croat Med J, 2021 Mar 05; 62(1). PMID: 33660962    Free PMC article.
N-3 Long-Chain Polyunsaturated Fatty Acids, Eicosapentaenoic and Docosahexaenoic Acid, and the Role of Supplementation during Cancer Treatment: A Scoping Review of Current Clinical Evidence.
Marnie Newell, Vera Mazurak, Lynne M Postovit, Catherine J Field.
Cancers (Basel), 2021 Apr 04; 13(6). PMID: 33801979    Free PMC article.
Review.
Variability in Breast Cancer Biomarker Assessment and the Effect on Oncological Treatment Decisions: A Nationwide 5-Year Population-Based Study.
Balazs Acs, Irma Fredriksson, +6 authors, Johan Hartman.
Cancers (Basel), 2021 Apr 04; 13(5). PMID: 33803148    Free PMC article.
Detection of Genomically Aberrant Cells within Circulating Tumor Microemboli (CTMs) Isolated from Early-Stage Breast Cancer Patients.
Marco Silvestri, Carolina Reduzzi, +12 authors, Vera Cappelletti.
Cancers (Basel), 2021 Apr 04; 13(6). PMID: 33808748    Free PMC article.
Expression of Phosphorylated BRD4 Is Markedly Associated with the Activation Status of the PP2A Pathway and Shows a Strong Prognostic Value in Triple Negative Breast Cancer Patients.
Marta Sanz-Álvarez, Ion Cristóbal, +9 authors, Federico Rojo.
Cancers (Basel), 2021 Apr 04; 13(6). PMID: 33809005    Free PMC article.
Individualized Prediction of Breast Cancer Survival Using Flexible Parametric Survival Modeling: Analysis of a Hospital-Based National Clinical Cancer Registry.
Donsuk Pongnikorn, Phichayut Phinyo, +3 authors, Boonying Siribumrungwong.
Cancers (Basel), 2021 Apr 04; 13(7). PMID: 33805407    Free PMC article.
Endocrine Therapy-related Endocrinopathies-Biology, Prevalence and Implications for the Management of Breast Cancer.
Kristy A Brown, Eleni Andreopoulou, Panagiota Andreopoulou.
Oncol Hematol Rev, 2021 Apr 13; 16(1). PMID: 33841882    Free PMC article.
Can We Reliably Identify the Pathological Outcomes of Neoadjuvant Chemotherapy in Patients with Breast Cancer? Development and Validation of a Logistic Regression Nomogram Based on Preoperative Factors.
Jian Zhang, Linhai Xiao, +3 authors, Ke Wang.
Ann Surg Oncol, 2020 Oct 24; 28(5). PMID: 33095360    Free PMC article.
The Proper Ki-67 Cut-Off in Hormone Responsive Breast Cancer: A Monoinstitutional Analysis with Long-Term Follow-Up.
Augusto Lombardi, Rachele Lazzeroni, +2 authors, Claudio Amanti.
Breast Cancer (Dove Med Press), 2021 Apr 16; 13. PMID: 33854368    Free PMC article.
PathoNet introduced as a deep neural network backend for evaluation of Ki-67 and tumor-infiltrating lymphocytes in breast cancer.
Farzin Negahbani, Rasool Sabzi, +5 authors, Amirreza Dehghanian.
Sci Rep, 2021 Apr 21; 11(1). PMID: 33875676    Free PMC article.
GATA3 as an Adjunct Prognostic Factor in Breast Cancer Patients with Less Aggressive Disease: A Study with a Review of the Literature.
Patrizia Querzoli, Massimo Pedriali, +3 authors, Elisabetta Kuhn.
Diagnostics (Basel), 2021 Apr 04; 11(4). PMID: 33800667    Free PMC article.
Unraveling tumor-immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy.
Alejandro Jiménez-Sánchez, Paulina Cybulska, +31 authors, Martin L Miller.
Nat Genet, 2020 Jun 03; 52(6). PMID: 32483290
Temozolomide alone or in combination with capecitabine in patients with advanced neuroendocrine neoplasms: an Italian multicenter real-world analysis.
Francesca Spada, Patrick Maisonneuve, +10 authors, Nicola Fazio.
Endocrine, 2020 Jul 24; 72(1). PMID: 32700133
Quality of Histopathological Reporting in Breast Cancer: Results From Four South African Breast Units.
Armand Toma, Daniel O'Neil, +11 authors, Sarah Nietz.
JCO Glob Oncol, 2021 Jan 13; 7. PMID: 33434068    Free PMC article.
mRNA profiling of a well-differentiated G1 pancreatic NET correlates with immunohistochemistry profile: a case report.
Abhirami Venugopal, Jessie Gillick-Walker, +2 authors, M Leigh Ackland.
BMC Gastroenterol, 2021 Apr 29; 21(1). PMID: 33906633    Free PMC article.
Immunohistochemical Expression of Five Protein Combinations Revealed as Prognostic Markers in Asian Oral Cancer.
Hui-Ching Wang, Chien-Jung Chiang, +4 authors, Grace S Shieh.
Front Genet, 2021 May 04; 12. PMID: 33936170    Free PMC article.
PONDx: real-life utilization and decision impact of the 21-gene assay on clinical practice in Italy.
Francesco Cognetti, Riccardo Masetti, +28 authors, Sandro Barni.
NPJ Breast Cancer, 2021 May 07; 7(1). PMID: 33953182    Free PMC article.
Current Biomarkers for Precision Medicine in Breast Cancer.
Soo Kyung Ahn, So-Youn Jung.
Adv Exp Med Biol, 2021 May 14; 1187. PMID: 33983588
Prognostic relevance of Ki67 expression in primary male breast cancer: determination of cut-off points by different evaluation methods and statistical examinations.
Melanie Erices-Leclercq, Sabine Lubig, +4 authors, Lars Schröder.
J Cancer Res Clin Oncol, 2021 May 16;. PMID: 33991247
Ki67 and progesterone receptor status predicts sensitivity to palbociclib: a real-world study.
Xiying Shao, Yabing Zheng, +13 authors, Xiaojia Wang.
Ann Transl Med, 2021 May 15; 9(8). PMID: 33987405    Free PMC article.
[Breast cancer and pregnancy: about 15 cases collected at the maternity center Monastir, Tunisia].
Ahmed Hajji, Houda El Mhabrech, +5 authors, Raja Faleh.
Pan Afr Med J, 2021 May 18; 38. PMID: 33995786    Free PMC article.
Enhancing the in vitro and in vivo activity of itraconazole against breast cancer using miltefosine-modified lipid nanocapsules.
Nabila A El-Sheridy, Riham M El-Moslemany, +2 authors, Labiba K El-Khordagui.
Drug Deliv, 2021 May 08; 28(1). PMID: 33960245    Free PMC article.
The impact of progesterone receptor negativity on oncological outcomes in oestrogen-receptor-positive breast cancer.
M G Davey, É J Ryan, +8 authors, A J Lowery.
BJS Open, 2021 May 21; 5(3). PMID: 34013318    Free PMC article.
Comparison of hormone-induced mRNA and protein biomarker expression changes in breast cancer cells.
Sarah M Bernhardt, Pallave Dasari, +3 authors, Wendy V Ingman.
Breast Cancer Res Treat, 2021 Jun 01; 187(3). PMID: 34057651
Circulating Tumor Cell Clusters Are Frequently Detected in Women with Early-Stage Breast Cancer.
Carolina Reduzzi, Serena Di Cosimo, +13 authors, Vera Cappelletti.
Cancers (Basel), 2021 Jun 03; 13(10). PMID: 34068368    Free PMC article.
KI-67 LI Expression in Triple-Negative Breast Cancer Patients and Its Significance.
Maria A Arafah, Abderrahman Ouban, Omar Z Ameer, Ko Jin Quek.
Breast Cancer (Auckl), 2021 Jun 24; 15. PMID: 34158798    Free PMC article.
A new tool for technical standardization of the Ki67 immunohistochemical assay.
Thazin Nwe Aung, Balazs Acs, +10 authors, David L Rimm.
Mod Pathol, 2021 Feb 05; 34(7). PMID: 33536573    Free PMC article.
CD155 Promotes the Progression of Cervical Cancer Cells Through AKT/mTOR and NF-κB Pathways.
Lu Liu, Ying Wang, +7 authors, Youzhong Zhang.
Front Oncol, 2021 Jun 25; 11. PMID: 34164340    Free PMC article.
The Guiding Significance of the Number of Positive Sentinel Lymph Nodes in Frozen Section for Intraoperative Axillary Dissection in Early Breast Cancer.
Chenlu Liang, Liuyi Li, +2 authors, Yang Yu.
Cancer Manag Res, 2021 Jun 26; 13. PMID: 34168499    Free PMC article.
The increasing importance of histologic grading in tailoring adjuvant systemic therapy in 30,843 breast cancer patients.
C van Dooijeweert, I O Baas, +3 authors, E van der Wall.
Breast Cancer Res Treat, 2021 Feb 01; 187(2). PMID: 33517555    Free PMC article.
Evaluating the Clinical Utility of Routine Sentinel Lymph Node Biopsy and the Value of Adjuvant Chemotherapy in Elderly Patients Diagnosed With Oestrogen Receptor Positive, Clinically Node Negative Breast Cancer.
Matthew G Davey, Éanna J Ryan, +4 authors, Aoife J Lowery.
Breast Cancer (Auckl), 2021 Jun 29; 15. PMID: 34177266    Free PMC article.
Prediction of Invasive Breast Cancer Using Mass Characteristic Frequency and Elasticity in Correlation with Prognostic Histologic Features and Immunohistochemical Biomarkers.
Juanjuan Gu, Eric C Polley, +3 authors, Azra Alizad.
Ultrasound Med Biol, 2021 May 18; 47(8). PMID: 33994231    Free PMC article.
Clinicopathological response to neoadjuvant therapies and pathological complete response as a biomarker of survival in human epidermal growth factor receptor-2 enriched breast cancer - A retrospective cohort study.
Matthew G Davey, Eoin Kerin, +13 authors, Michael J Kerin.
Breast, 2021 Jun 26; 59. PMID: 34171619    Free PMC article.
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
Xinyan Jiao, Bo Wang, +6 authors, Peijun Liu.
BMC Cancer, 2021 Jul 02; 21(1). PMID: 34193109    Free PMC article.
Ceramide expression in relation to breast cancer molecular subtypes in Saudi women.
Aliyah Almomen, Maria Arafah, +7 authors, Musaed Alkholief.
Saudi Pharm J, 2021 Jul 02; 29(6). PMID: 34194268    Free PMC article.
Ki67 Assessment in Breast Cancer: Are We There Yet?
Jorge S Reis-Filho, Nancy E Davidson.
J Natl Cancer Inst, 2020 Dec 29; 113(7). PMID: 33369665    Free PMC article.
Multiparametric Integrated 18F-FDG PET/MRI-Based Radiomics for Breast Cancer Phenotyping and Tumor Decoding.
Lale Umutlu, Julian Kirchner, +12 authors, Katja Pinker-Domenig.
Cancers (Basel), 2021 Jul 03; 13(12). PMID: 34208197    Free PMC article.
A Novel Ruthenium-Fluvastatin Complex Downregulates SNCG Expression to Modulate Breast Carcinoma Cell Proliferation and Apoptosis via Activating the PI3K/Akt/mTOR/VEGF/MMP9 Pathway.
Wei Liang, Junfeng Shi, Haiyan Xia, Xiaowei Wei.
Oxid Med Cell Longev, 2021 Jul 06; 2021. PMID: 34221232    Free PMC article.
Role of docosahexaenoic acid in enhancement of docetaxel action in patient-derived breast cancer xenografts.
Marnie Newell, Susan Goruk, +2 authors, Catherine J Field.
Breast Cancer Res Treat, 2019 Jun 27; 177(2). PMID: 31236812
Ki67 Index Changes and Tumor-Infiltrating Lymphocyte Levels Impact the Prognosis of Triple-Negative Breast Cancer Patients With Residual Disease After Neoadjuvant Chemotherapy.
Yihua Wang, Beige Zong, +5 authors, Shengchun Liu.
Front Oncol, 2021 Jul 09; 11. PMID: 34235079    Free PMC article.
KMT2C is a potential biomarker of prognosis and chemotherapy sensitivity in breast cancer.
Xinhua Liu, Rongfang Qiu, +4 authors, Yang Yang.
Breast Cancer Res Treat, 2021 Jul 10;. PMID: 34240274
Clinical, Radiometabolic and Immunologic Effects of Olaparib in Locally Advanced Triple Negative Breast Cancer: The OLTRE Window of Opportunity Trial.
Francesco Schettini, Silvia Paola Corona, +24 authors, Daniele Generali.
Front Oncol, 2021 Jul 16; 11. PMID: 34262869    Free PMC article.
Single Cell Genetic Profiling of Tumors of Breast Cancer Patients Aged 50 Years and Older Reveals Enormous Intratumor Heterogeneity Independent of Individual Prognosis.
Anna-Sophie Liegmann, Kerstin Heselmeyer-Haddad, +11 authors, Thomas Ried.
Cancers (Basel), 2021 Jul 21; 13(13). PMID: 34282768    Free PMC article.
TBC1D9: An Important Modulator of Tumorigenesis in Breast Cancer.
Charu Kothari, Alisson Clemenceau, +5 authors, Francine Durocher.
Cancers (Basel), 2021 Jul 25; 13(14). PMID: 34298771    Free PMC article.