Journal Article
. 2011 Nov; 6:110.
doi: 10.1186/1746-1596-6-110.

History and structures of telecommunication in pathology, focusing on open access platforms

Klaus Kayser 1 Stephan Borkenfeld  Amina Djenouni  Gian Kayser  
  • PMID: 22059444
  •     40 References
  •     5 citations


Background: Telecommunication has matured to a broadly applied tool in diagnostic pathology.

Technology And Systems: Contemporary with the development of fast electronic communication lines (Integrated digital network services (ISDN), broad band connections, and fibre optics, as well as the digital imaging technology (digital camera), telecommunication in tissue--based diagnosis (telepathology) has matured. Open access (internet) and server--based communication have induced the development of specific medical information platforms, such as iPATH, UICC-TPCC (telepathology consultation centre of the Union International against Cancer), or the Armed Forces Institute of Pathology (AFIP) teleconsultation system. They have been closed, and are subject to be replaced by specific open access forums (Medical Electronic Expert Communication System (MECES) with embedded virtual slide (VS) technology). MECES uses php language, data base driven mySqL architecture, X/L-AMPP infrastructure, and browser friendly W3C conform standards.

Experiences: The server--based medical communication systems (AFIP, iPATH, UICC-TPCC) have been reported to be a useful and easy to handle tool for expert consultation. Correct sampling and evaluation of transmitted still images by experts reported revealed no or only minor differences to the original images and good practice of the involved experts. β tests with the new generation medical expert consultation systems (MECES) revealed superior results in terms of performance, still image viewing, and system handling, especially as this is closely related to the use of so--called social forums (facebook, youtube, etc.).

Benefits And Expectations: In addition to the acknowledged advantages of the former established systems (assistance of pathologists working in developing countries, diagnosis confirmation, international information exchange, etc.), the new generation offers additional benefits such as acoustic information transfer, assistance in image screening, VS technology, and teaching in diagnostic sampling, judgement, and verification.

Cost-effective dynamic telepathology in the Mohs surgery laboratory utilizing iChat AV videoconferencing software.
Jeffrey K McKenna, Scott R Florell.
Dermatol Surg, 2007 Jan 12; 33(1). PMID: 17214680
From telepathology to virtual pathology institution: the new world of digital pathology.
K Kayser, G Kayser, D Radziszowski, A Oehmann.
Rom J Morphol Embryol, 2005 Apr 26; 45. PMID: 15847374
Prerecorded telemedicine.
Vincenzo Della Mea.
J Telemed Telecare, 2005 Sep 20; 11(6). PMID: 16168163
Telepathology support for the Mediterranean Institute for Transplantation and Advanced Specialized Therapies.
Y Yagi.
Telemed Today, 2001 Feb 24; 8(3). PMID: 11183304
How to measure image quality in tissue-based diagnosis (diagnostic surgical pathology).
Klaus Kayser, Jürgen Görtler, +5 authors, Gian Kayser.
Diagn Pathol, 2008 Aug 05; 3 Suppl 1. PMID: 18673499    Free PMC article.
Comparison of telepathology services.
Kurt Brauchli, Martin Oberholzer.
J Telemed Telecare, 2004 Oct 21; 10(5). PMID: 15494091
The Internet for pathologists: a simple schema for evaluating pathology-related Web sites and a catalog of sites useful for practicing pathologists.
Geoffrey Talmon, Neil A Abrahams.
Arch Pathol Lab Med, 2005 May 26; 129(6). PMID: 15913421
Telepathology by the Internet.
I Petersen, G Wolf, K Roth, K Schlüns.
J Pathol, 2000 Apr 18; 191(1). PMID: 10767712
Interdisciplinary telecommunication and expert teleconsultation in diagnostic pathology: present status and future prospects.
Klaus Kayser.
J Telemed Telecare, 2003 Jan 23; 8(6). PMID: 12537919
Standardization in digital pathology: Supplement 145 of the DICOM standards.
Rajendra Singh, Lauren Chubb, Liron Pantanowitz, Anil Parwani.
J Pathol Inform, 2011 Jun 03; 2. PMID: 21633489    Free PMC article.
Antibody microarrays as tools for biomarker discovery.
Marta Sanchez-Carbayo.
Methods Mol Biol, 2011 Sep 09; 785. PMID: 21901599
Driving to pathology's future: corporate innovation as an engine for change.
Mark Newburger.
Arch Pathol Lab Med, 2009 Apr 28; 133(4). PMID: 19391652
Review of imaging solutions for integrated quantitative immunohistochemistry in the Pathology daily practice.
Marcial García Rojo, Gloria Bueno, Janina Slodkowska.
Folia Histochem Cytobiol, 2010 Feb 19; 47(3). PMID: 20164017
Telemicroscopy by the Internet revisited.
K Brauchli, H Christen, +3 authors, M Oberholzer.
J Pathol, 2002 Jan 17; 196(2). PMID: 11793377
Teleeducation and telepathology for open and distance education.
J Szymas.
Anal Cell Pathol, 2001 May 08; 21(3-4). PMID: 11339566    Free PMC article.
Realtime telemedicine.
Richard Wootton.
J Telemed Telecare, 2006 Oct 25; 12(7). PMID: 17059648
[KRAS mutation testing in therapeutic algorithm for treatment of metastatic colorectal carcinoma].
Lenka Dubská, Martina Vyskocilová, +19 authors, Ales Ryska.
Cas Lek Cesk, 2011 Jul 15; 150(6). PMID: 21751504
Image standards in tissue-based diagnosis (diagnostic surgical pathology).
Klaus Kayser, Jürgen Görtler, +3 authors, Gian Kayser.
Diagn Pathol, 2008 Apr 22; 3. PMID: 18423031    Free PMC article.
Modern telepathology: a distributed system with open standards.
Martin Oberholzer, Heinz Christen, +6 authors, Kurt Brauchli.
Curr Probl Dermatol, 2002 Dec 11; 32. PMID: 12471998
Theory of sampling and its application in tissue based diagnosis.
Klaus Kayser, Holger Schultz, +3 authors, Ekkehard Vollmer.
Diagn Pathol, 2009 Feb 18; 4. PMID: 19220904    Free PMC article.
iPath - a Telemedicine Platform to Support Health Providers in Low Resource Settings.
K Brauchli, D O'mahony, L Banach, M Oberholzer.
Stud Health Technol Inform, 2005 Jun 01; 114. PMID: 15923755
Comparison of different telepathology solutions for primary frozen section diagnostic.
P Hufnagl, G Bayer, +4 authors, M Dietel.
Anal Cell Pathol, 2001 May 08; 21(3-4). PMID: 11339563    Free PMC article.
Telepathology in Europe.
K Kayser.
Anal Cell Pathol, 2001 May 08; 21(3-4). PMID: 11339573    Free PMC article.
Recent advances in standards for Collaborative Digital Anatomic Pathology.
Christel Daniel, François Macary, +4 authors, Vincenzo Della Mea.
Diagn Pathol, 2011 Apr 22; 6 Suppl 1. PMID: 21489187    Free PMC article.
Experience based approach to interactive versus "store and forward" telepathology.
Danilovic, Seiwerth, +3 authors, Dzubur.
Adv Clin Path, 1999 Jun 08; 2(2). PMID: 10358376
The UICC Telepathology Consultation Center. International Union Against Cancer. A global approach to improving consultation for pathologists in cancer diagnosis.
M Dietel, T N Nguyen-Dobinsky, P Hufnagl.
Cancer, 2000 Jul 18; 89(1). PMID: 10897017
Introducing videoconferencing into educational oncopathology seminars: technical aspects, user satisfaction and open issues.
Vincenzo Della Mea, Antonino Carbone, Ermes Greatti, Carlo A Beltrami.
J Telemed Telecare, 2003 Apr 18; 9(2). PMID: 12699579
Real-time teleneuropathology for a second opinion of neurooncological cases.
J Szymaś, W Papierz, M Danilewicz.
Folia Neuropathol, 2000 Nov 01; 38(1). PMID: 11057034
Telepathology on the Solomon Islands--two years' experience with a hybrid Web- and email-based telepathology system.
K Brauchli, R Jagilly, +4 authors, M Oberholzer.
J Telemed Telecare, 2004 Dec 18; 10 Suppl 1. PMID: 15603597
AI (artificial intelligence) in histopathology--from image analysis to automated diagnosis.
Klaus Kayser, Jürgen Görtler, +4 authors, Gian Kayser.
Folia Histochem Cytobiol, 2010 Feb 19; 47(3). PMID: 20164018
[Electronic communication in medicine].
M Dietel, P Hufnagl.
Z Arztl Fortbild Qualitatssich, 2001 Nov 02; 95(9). PMID: 11688217
Telediagnosis of transbronchial fine needle aspirations--a feasibility study.
K Kayser, G Kayser, H D Becker, F Herth.
Anal Cell Pathol, 2001 May 08; 21(3-4). PMID: 11339569    Free PMC article.
Innovations in medical imaging and virtual microscopy.
Ronald S Weinstein.
Hum Pathol, 2005 May 14; 36(4). PMID: 15891989
[Anatomic pathology workflow. IHE: modeling based on current developments in HL7 and DICOM].
T Schrader, B Beckwith, +2 authors, C Daniel.
Pathologe, 2008 Oct 10; 29 Suppl 2. PMID: 18843490
The iPath telemedicine platform.
Kurt Brauchli, Martin Oberholzer.
J Telemed Telecare, 2005 Dec 27; 11 Suppl 2. PMID: 16375782
Prognostic factors and predictive models in renal cell carcinoma: a contemporary review.
Maxine Sun, Shahrokh F Shariat, +6 authors, Pierre I Karakiewicz.
Eur Urol, 2011 Jul 12; 60(4). PMID: 21741163
Highly Cited. Review.
Histology and outcomes of newly detected lung lesions in melanoma patients.
E C Smyth, M Hsu, K S Panageas, P B Chapman.
Ann Oncol, 2011 Aug 09; 23(3). PMID: 21821550
The virtual slide in the promotion of cytologic and hystologic quality in oncologic screenings.
Arrigo Bondi, Paola Pierotti, Paola Crucitti, Stefania Lega.
Ann Ist Super Sanita, 2010 Jun 23; 46(2). PMID: 20567065
Telepathology overview: from concept to implementation.
R S Weinstein, M R Descour, +9 authors, B E Dunn.
Hum Pathol, 2002 Jan 05; 32(12). PMID: 11774159
Image quality issues in a static image-based telepathology consultation practice.
Bruce H Williams, In Soon Hong, +3 authors, Timothy J O'Leary.
Hum Pathol, 2003 Dec 24; 34(12). PMID: 14691906
Development of a teledermatopathology consultation system using virtual slides.
Ikunori Nakayama, Tsubasa Matsumura, +5 authors, Takashi Sawai.
Diagn Pathol, 2012 Dec 15; 7. PMID: 23237667    Free PMC article.
Experience with multimodality telepathology at the University of Pittsburgh Medical Center.
Liron Pantanowitz, Clayton A Wiley, +5 authors, Anil V Parwani.
J Pathol Inform, 2013 Feb 02; 3. PMID: 23372986    Free PMC article.
What is a virtual multidisciplinary team (vMDT)?
A J Munro, S Swartzman.
Br J Cancer, 2013 Jun 13; 108(12). PMID: 23756866    Free PMC article.
The history of pathology informatics: A global perspective.
Seung Park, Anil V Parwani, +15 authors, Liron Pantanowitz.
J Pathol Inform, 2013 Jul 23; 4. PMID: 23869286    Free PMC article.
Invention and Early History of Telepathology (1985-2000).
Ronald S Weinstein, Michael J Holcomb, Elizabeth A Krupinski.
J Pathol Inform, 2019 Feb 21; 10. PMID: 30783545    Free PMC article.