Journal Article
. 2011 Dec;379(9814).
doi: 10.1016/S0140-6736(11)61625-5.

Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100,000 women in 123 randomised trials

Early Breast Cancer Trialists' Collaborative Group (EBCTCG)  R Peto  C Davies  J Godwin  R Gray  H C Pan  M Clarke  D Cutter  S Darby  P McGale  C Taylor  Y C Wang  J Bergh  A Di Leo  K Albain  S Swain  M Piccart  K Pritchard  
  • PMID: 22152853
  •     36 References
  •     504 citations


Background: Moderate differences in efficacy between adjuvant chemotherapy regimens for breast cancer are plausible, and could affect treatment choices. We sought any such differences.

Methods: We undertook individual-patient-data meta-analyses of the randomised trials comparing: any taxane-plus-anthracycline-based regimen versus the same, or more, non-taxane chemotherapy (n=44,000); one anthracycline-based regimen versus another (n=7000) or versus cyclophosphamide, methotrexate, and fluorouracil (CMF; n=18,000); and polychemotherapy versus no chemotherapy (n=32,000). The scheduled dosages of these three drugs and of the anthracyclines doxorubicin (A) and epirubicin (E) were used to define standard CMF, standard 4AC, and CAF and CEF. Log-rank breast cancer mortality rate ratios (RRs) are reported.

Findings: In trials adding four separate cycles of a taxane to a fixed anthracycline-based control regimen, extending treatment duration, breast cancer mortality was reduced (RR 0·86, SE 0·04, two-sided significance [2p]=0·0005). In trials with four such extra cycles of a taxane counterbalanced in controls by extra cycles of other cytotoxic drugs, roughly doubling non-taxane dosage, there was no significant difference (RR 0·94, SE 0·06, 2p=0·33). Trials with CMF-treated controls showed that standard 4AC and standard CMF were equivalent (RR 0·98, SE 0·05, 2p=0·67), but that anthracycline-based regimens with substantially higher cumulative dosage than standard 4AC (eg, CAF or CEF) were superior to standard CMF (RR 0·78, SE 0·06, 2p=0·0004). Trials versus no chemotherapy also suggested greater mortality reductions with CAF (RR 0·64, SE 0·09, 2p<0·0001) than with standard 4AC (RR 0·78, SE 0·09, 2p=0·01) or standard CMF (RR 0·76, SE 0·05, 2p<0·0001). In all meta-analyses involving taxane-based or anthracycline-based regimens, proportional risk reductions were little affected by age, nodal status, tumour diameter or differentiation (moderate or poor; few were well differentiated), oestrogen receptor status, or tamoxifen use. Hence, largely independently of age (up to at least 70 years) or the tumour characteristics currently available to us for the patients selected to be in these trials, some taxane-plus-anthracycline-based or higher-cumulative-dosage anthracycline-based regimens (not requiring stem cells) reduced breast cancer mortality by, on average, about one-third. 10-year overall mortality differences paralleled breast cancer mortality differences, despite taxane, anthracycline, and other toxicities.

Interpretation: 10-year gains from a one-third breast cancer mortality reduction depend on absolute risks without chemotherapy (which, for oestrogen-receptor-positive disease, are the risks remaining with appropriate endocrine therapy). Low absolute risk implies low absolute benefit, but information was lacking about tumour gene expression markers or quantitative immunohistochemistry that might help to predict risk, chemosensitivity, or both.

Funding: Cancer Research UK; British Heart Foundation; UK Medical Research Council.

Endocrine responsiveness and tailoring adjuvant therapy for postmenopausal lymph node-negative breast cancer: a randomized trial.
International Breast Cancer Study Group (IBCSG).
J Natl Cancer Inst, 2002 Jul 18; 94(14). PMID: 12122096
Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer.
I Craig Henderson, Donald A Berry, +16 authors, Larry Norton.
J Clin Oncol, 2003 Mar 15; 21(6). PMID: 12637460
Highly Cited.
Epirubicin-cyclophosphamide adjuvant chemotherapy plus tamoxifen administered concurrently versus sequentially: randomized phase III trial in postmenopausal node-positive breast cancer patients. A GEICAM 9401 study.
C Pico, M Martin, +18 authors, GEICAM Group.
Ann Oncol, 2003 Dec 18; 15(1). PMID: 14679124
Evidence of a castration-mediated effect of adjuvant cytotoxic chemotherapy in premenopausal breast cancer.
H Brincker, C Rose, +5 authors, K W Andersen.
J Clin Oncol, 1987 Nov 01; 5(11). PMID: 3316514
"Classical" CMF versus a 3-weekly intravenous CMF schedule in postmenopausal patients with advanced breast cancer. An EORTC Breast Cancer Co-operative Group Phase III Trial (10808).
E Engelsman, J C Klijn, +5 authors, R Sylvester.
Eur J Cancer, 1991 Jan 01; 27(8). PMID: 1832904
Randomized trial of intensive cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer. National Cancer Institute of Canada Clinical Trials Group.
M N Levine, V H Bramwell, +15 authors, D Tu.
J Clin Oncol, 1998 Aug 15; 16(8). PMID: 9704715
Toremifene and tamoxifen are equally effective for early-stage breast cancer: first results of International Breast Cancer Study Group Trials 12-93 and 14-93.
International Breast Cancer Study Group, Olivia Pagani, +7 authors, Aron Goldhirsch.
Ann Oncol, 2004 Nov 20; 15(12). PMID: 15550579
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer.
Soonmyung Paik, Steven Shak, +12 authors, Norman Wolmark.
N Engl J Med, 2004 Dec 14; 351(27). PMID: 15591335
Highly Cited.
Long-term efficacy and toxicity of the FEC100 regimen.
Jacques M Bonneterre, French Adjuvant Study Group.
Oncology (Williston Park), 2005 Feb 03; 18(14 Suppl 14). PMID: 15685837
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials.
Early Breast Cancer Trialists' Collaborative Group (EBCTCG).
Lancet, 2005 May 17; 365(9472). PMID: 15894097
Highly Cited.
Risk of acute myeloid leukemia and myelodysplastic syndrome in trials of adjuvant epirubicin for early breast cancer: correlation with doses of epirubicin and cyclophosphamide.
Claudio Praga, Jonas Bergh, +16 authors, David Rogers.
J Clin Oncol, 2005 Jun 18; 23(18). PMID: 15961765
A conversation with Paul Meier. Interview by Harry M Marks.
Paul Meier.
Clin Trials, 2005 Nov 12; 1(1). PMID: 16281468
Randomized, controlled trial of cyclophosphamide, methotrexate, and fluorouracil versus cyclophosphamide, doxorubicin, and fluorouracil with and without tamoxifen for high-risk, node-negative breast cancer: treatment results of Intergroup Protocol INT-0102.
Laura F Hutchins, Stephanie J Green, +7 authors, C Kent Osborne.
J Clin Oncol, 2005 Nov 19; 23(33). PMID: 16293862
Estrogen-receptor status and outcomes of modern chemotherapy for patients with node-positive breast cancer.
Donald A Berry, Constance Cirrincione, +9 authors, Eric P Winer.
JAMA, 2006 Apr 13; 295(14). PMID: 16609087    Free PMC article.
Highly Cited.
Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer.
Soonmyung Paik, Gong Tang, +11 authors, Norman Wolmark.
J Clin Oncol, 2006 May 25; 24(23). PMID: 16720680
Highly Cited.
TAILORx: trial assigning individualized options for treatment (Rx).
Joseph A Sparano.
Clin Breast Cancer, 2006 Nov 10; 7(4). PMID: 17092406
Amenorrhea in premenopausal women after adjuvant chemotherapy for breast cancer.
Janice M Walshe, Neelima Denduluri, Sandra M Swain.
J Clin Oncol, 2006 Nov 30; 24(36). PMID: 17130515
Weekly paclitaxel in the adjuvant treatment of breast cancer.
Joseph A Sparano, Molin Wang, +7 authors, Nancy E Davidson.
N Engl J Med, 2008 Apr 19; 358(16). PMID: 18420499    Free PMC article.
Highly Cited.
Randomized phase 3 trial of fluorouracil, epirubicin, and cyclophosphamide alone or followed by Paclitaxel for early breast cancer.
Miguel Martín, Alvaro Rodríguez-Lescure, +33 authors, GEICAM 9906 Study Investigators.
J Natl Cancer Inst, 2008 May 29; 100(11). PMID: 18505968
Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures.
Pratyaksha Wirapati, Christos Sotiriou, +10 authors, Mauro Delorenzi.
Breast Cancer Res, 2008 Jul 30; 10(4). PMID: 18662380    Free PMC article.
Highly Cited.
Gene-expression signatures in breast cancer.
Christos Sotiriou, Lajos Pusztai.
N Engl J Med, 2009 Feb 21; 360(8). PMID: 19228622
Highly Cited. Review.
The MINDACT trial: the first prospective clinical validation of a genomic tool.
Fatima Cardoso, Martine Piccart-Gebhart, +2 authors, TRANSBIG Consortium.
Mol Oncol, 2007 Dec 01; 1(3). PMID: 19383299    Free PMC article.
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer.
Antonio C Wolff, M Elizabeth H Hammond, +21 authors, American Society of Clinical Oncology/College of American Pathologists.
Arch Pathol Lab Med, 2007 Jan 01; 131(1). PMID: 19548375
Highly Cited.
Is adjuvant chemotherapy of benefit for postmenopausal women who receive endocrine treatment for highly endocrine-responsive, node-positive breast cancer? International Breast Cancer Study Group Trials VII and 12-93.
Olivia Pagani, Shari Gelber, +14 authors, International Breast Cancer Study Group.
Breast Cancer Res Treat, 2008 Oct 28; 116(3). PMID: 18953651    Free PMC article.
Different dosage schedules for reducing cardiotoxicity in cancer patients receiving anthracycline chemotherapy.
Elvira C van Dalen, Helena J H van der Pal, Huib N Caron, Leontien Cm Kremer.
Cochrane Database Syst Rev, 2009 Oct 13; (4). PMID: 19821337
Systematic Review.
The 70-gene signature as a response predictor for neoadjuvant chemotherapy in breast cancer.
Marieke E Straver, Annuska M Glas, +7 authors, Sjoerd Rodenhuis.
Breast Cancer Res Treat, 2009 Feb 14; 119(3). PMID: 19214742
Meta-analysis of breast cancer outcomes in adjuvant trials of aromatase inhibitors versus tamoxifen.
Mitch Dowsett, Jack Cuzick, +16 authors, Richard Peto.
J Clin Oncol, 2009 Dec 02; 28(3). PMID: 19949017
Highly Cited.
Adjuvant chemotherapy and timing of tamoxifen in postmenopausal patients with endocrine-responsive, node-positive breast cancer: a phase 3, open-label, randomised controlled trial.
Kathy S Albain, William E Barlow, +18 authors, Breast Cancer Intergroup of North America.
Lancet, 2009 Dec 17; 374(9707). PMID: 20004966    Free PMC article.
Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial.
Kathy S Albain, William E Barlow, +20 authors, Breast Cancer Intergroup of North America.
Lancet Oncol, 2009 Dec 17; 11(1). PMID: 20005174    Free PMC article.
Highly Cited.
Prediction of risk of distant recurrence using the 21-gene recurrence score in node-negative and node-positive postmenopausal patients with breast cancer treated with anastrozole or tamoxifen: a TransATAC study.
Mitch Dowsett, Jack Cuzick, +11 authors, Steven Shak.
J Clin Oncol, 2010 Mar 10; 28(11). PMID: 20212256
Highly Cited.
Pathological complete response after preoperative systemic therapy and outcome: relevance of clinical and biologic baseline features.
Emilia Montagna, Vincenzo Bagnardi, +15 authors, Marco Colleoni.
Breast Cancer Res Treat, 2010 Jul 14; 124(3). PMID: 20625816
Current misconception 3: that subgroup-specific trial mortality results often provide a good basis for individualising patient care.
R Peto.
Br J Cancer, 2011 Mar 31; 104(7). PMID: 21448174    Free PMC article.
Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials.
Early Breast Cancer Trialists' Collaborative Group (EBCTCG), C Davies, +11 authors, R Peto.
Lancet, 2011 Aug 02; 378(9793). PMID: 21802721    Free PMC article.
Highly Cited.
Long-term toxic effects of adjuvant chemotherapy in breast cancer.
H A Azim, E de Azambuja, +2 authors, M J Piccart.
Ann Oncol, 2011 Feb 04; 22(9). PMID: 21289366
Concurrent vs sequential adjuvant chemotherapy and hormone therapy in breast cancer: a multicenter randomized phase III trial.
Davide Bedognetti, Mario Roberto Sertoli, +12 authors, Paolo Bruzzi.
J Natl Cancer Inst, 2011 Sep 17; 103(20). PMID: 21921285    Free PMC article.
Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the Genomic Health recurrence score in early breast cancer.
Jack Cuzick, Mitch Dowsett, +10 authors, John F Forbes.
J Clin Oncol, 2011 Oct 13; 29(32). PMID: 21990413
Highly Cited.
Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials.
Early Breast Cancer Trialists' Collaborative Group (EBCTCG), S Darby, +13 authors, R Peto.
Lancet, 2011 Oct 25; 378(9804). PMID: 22019144    Free PMC article.
Highly Cited. Review.
Poor-prognosis estrogen receptor- positive disease: present and future clinical solutions.
Per E Lønning.
Ther Adv Med Oncol, 2012 May 17; 4(3). PMID: 22590486    Free PMC article.
Extended benefit from sequential administration of docetaxel after standard fluorouracil, epirubicin, and cyclophosphamide regimen for node-positive breast cancer: the 8-year follow-up results of the UNICANCER-PACS01 trial.
Bruno Coudert, Bernard Asselain, +18 authors, UNICANCER Breast Group.
Oncologist, 2012 May 23; 17(7). PMID: 22610153    Free PMC article.
Biological characterization and selection criteria of adjuvant chemotherapy for early breast cancer: experience from the Italian observational NEMESI study.
Matteo Clavarezza, Giorgio Mustacchi, +13 authors, Marco Venturini.
BMC Cancer, 2012 Jun 08; 12. PMID: 22672524    Free PMC article.
Differential response of immunohistochemically defined breast cancer subtypes to anthracycline-based adjuvant chemotherapy with or without paclitaxel.
George Fountzilas, Urania Dafni, +18 authors, Meletios A Dimopoulos.
PLoS One, 2012 Jun 09; 7(6). PMID: 22679488    Free PMC article.
Breast cancer in young women.
Steven A Narod.
Nat Rev Clin Oncol, 2012 Jun 27; 9(8). PMID: 22733233
p53, a target of estrogen receptor (ER) α, modulates DNA damage-induced growth suppression in ER-positive breast cancer cells.
Crystal E Berger, Yingjuan Qian, +2 authors, Xinbin Chen.
J Biol Chem, 2012 Jul 13; 287(36). PMID: 22787161    Free PMC article.
MicroRNAs and drug resistance of breast cancer: basic evidence and clinical applications.
Wei Tian, Junqing Chen, Haifei He, Yongchuan Deng.
Clin Transl Oncol, 2012 Aug 24; 15(5). PMID: 22914907
Impact of modern chemotherapy on the survival of women presenting with de novo metastatic breast cancer.
Sumanta K Pal, Mary Dehaven, +5 authors, Joanne Mortimer.
BMC Cancer, 2012 Oct 02; 12. PMID: 23020297    Free PMC article.
Running on empty: cardiovascular reserve capacity and late effects of therapy in cancer survivorship.
Graeme J Koelwyn, Michel Khouri, +2 authors, Lee W Jones.
J Clin Oncol, 2012 Oct 10; 30(36). PMID: 23045598    Free PMC article.
Long-term outcome of neoadjuvant systemic therapy for locally advanced breast cancer in routine clinical practice.
Domenico Angelucci, Nicola Tinari, +13 authors, Clara Natoli.
J Cancer Res Clin Oncol, 2012 Oct 12; 139(2). PMID: 23052698    Free PMC article.
Publication of tumor marker research results: the necessity for complete and transparent reporting.
Lisa M McShane, Daniel F Hayes.
J Clin Oncol, 2012 Oct 17; 30(34). PMID: 23071235    Free PMC article.
Update on triple-negative breast cancer: prognosis and management strategies.
Olivier Brouckaert, Hans Wildiers, Giuseppe Floris, Patrick Neven.
Int J Womens Health, 2012 Oct 17; 4. PMID: 23071421    Free PMC article.
Older patients with breast cancer: is there bias in the treatment they receive?
Christos Markopoulos, Willemien van de Water.
Ther Adv Med Oncol, 2012 Nov 03; 4(6). PMID: 23118807    Free PMC article.
Taxanes for the treatment of metastatic breast cancer.
W J Gradishar.
Breast Cancer (Auckl), 2012 Nov 08; 6. PMID: 23133315    Free PMC article.
Weight-based chemotherapy dosing in obese patients with cancer: back to the future.
Gary H Lyman.
J Oncol Pract, 2012 Nov 28; 8(4). PMID: 23181001    Free PMC article.
Phosphorylation of p90RSK is associated with increased response to neoadjuvant chemotherapy in ER-positive breast cancer.
Hyeong-Gon Moon, Jae Kyo Yi, +9 authors, Dong-Young Noh.
BMC Cancer, 2012 Dec 12; 12. PMID: 23216670    Free PMC article.
Editorial. Preface.
Marc Lippman.
J Mammary Gland Biol Neoplasia, 2012 Dec 19; 17(3-4). PMID: 23247594
Aberrant Keap1 methylation in breast cancer and association with clinicopathological features.
Raffaela Barbano, Lucia Anna Muscarella, +13 authors, Paola Parrella.
Epigenetics, 2012 Dec 20; 8(1). PMID: 23249627    Free PMC article.
Endo180 modulation by bisphosphonates and diagnostic accuracy in metastatic breast cancer.
C Palmieri, M P Caley, +8 authors, J Sturge.
Br J Cancer, 2012 Dec 22; 108(1). PMID: 23257899    Free PMC article.
Declining second primary ovarian cancer after first primary breast cancer.
Sara J Schonfeld, Amy Berrington de Gonzalez, +2 authors, William F Anderson.
J Clin Oncol, 2013 Jan 04; 31(6). PMID: 23284037    Free PMC article.
Tissue biomarkers of breast cancer and their association with conventional pathologic features.
L Chung, S Shibli, +4 authors, R C Baxter.
Br J Cancer, 2013 Jan 10; 108(2). PMID: 23299531    Free PMC article.
Mammographic density as a predictor of breast cancer survival: the Multiethnic Cohort.
Gertraud Maskarinec, Ian S Pagano, +3 authors, Laurence N Kolonel.
Breast Cancer Res, 2013 Jan 24; 15(1). PMID: 23339436    Free PMC article.
[Breast cancer. Individualized therapy concepts].
N Harbeck, R Wuerstlein.
Internist (Berl), 2013 Feb 02; 54(2). PMID: 23371261
A prospective evaluation of a breast cancer prognosis signature in the observational RASTER study.
C A Drukker, J M Bueno-de-Mesquita, +10 authors, S C Linn.
Int J Cancer, 2013 Feb 02; 133(4). PMID: 23371464    Free PMC article.
Adjuvant chemotherapy for breast cancer in a patient with primary autoimmune neutropenia.
Michael Trus, Kavita Dhamanaskar, +3 authors, Louise Bordeleau.
Breast Cancer (Auckl), 2013 Feb 27; 7. PMID: 23440399    Free PMC article.
Next-generation sequencing: a powerful tool for the discovery of molecular markers in breast ductal carcinoma in situ.
Hitchintan Kaur, Shihong Mao, +4 authors, Raymond R Mattingly.
Expert Rev Mol Diagn, 2013 Mar 13; 13(2). PMID: 23477556    Free PMC article.
Pharmacogenomics of breast cancer therapy: an update.
Kelly Westbrook, Vered Stearns.
Pharmacol Ther, 2013 Mar 19; 139(1). PMID: 23500718    Free PMC article.
Current approaches for neoadjuvant chemotherapy in breast cancer.
Roisin M Connolly, Vered Stearns.
Eur J Pharmacol, 2013 Apr 03; 717(1-3). PMID: 23545358    Free PMC article.
The combination of Ki67, histological grade and estrogen receptor status identifies a low-risk group among 1,854 chemo-naïve women with N0/N1 primary breast cancer.
Carina Strand, Martin Bak, +13 authors, Mårten Fernö.
Springerplus, 2013 Apr 06; 2(1). PMID: 23560250    Free PMC article.
Effect of body mass index on tumor characteristics and disease-free survival in patients from the HER2-positive adjuvant trastuzumab trial N9831.
Jennifer A Crozier, Alvaro Moreno-Aspitia, +3 authors, Edith A Perez.
Cancer, 2013 Apr 16; 119(13). PMID: 23585192    Free PMC article.
HER2-positive breast cancer patients receiving trastuzumab treatment obtain prognosis comparable with that of HER2-negative breast cancer patients.
Tao Qin, Zhongyu Yuan, +5 authors, Shusen Wang.
Onco Targets Ther, 2013 May 01; 6. PMID: 23630425    Free PMC article.
Taxane benefit in breast cancer--a role for grade and chromosomal stability.
Roger P A'Hern, Mariam Jamal-Hanjani, +4 authors, Charles Swanton.
Nat Rev Clin Oncol, 2013 May 08; 10(6). PMID: 23648828
Association between delayed initiation of adjuvant CMF or anthracycline-based chemotherapy and survival in breast cancer: a systematic review and meta-analysis.
Ke-Da Yu, Sheng Huang, +2 authors, Zhi-Ming Shao.
BMC Cancer, 2013 May 18; 13. PMID: 23679207    Free PMC article.
Systematic Review.
The benefits and harms of breast cancer screening: an independent review.
M G Marmot, D G Altman, +3 authors, M Wilcox.
Br J Cancer, 2013 Jun 08; 108(11). PMID: 23744281    Free PMC article.
Highly Cited. Review.
Common variants in genes coding for chemotherapy metabolizing enzymes, transporters, and targets: a case-control study of contralateral breast cancer risk in the WECARE Study.
Jennifer D Brooks, Sharon N Teraoka, +11 authors, Jane C Figueiredo.
Cancer Causes Control, 2013 Jun 19; 24(8). PMID: 23775025    Free PMC article.
Video Q&A: molecular profiling of breast cancer.
Carlos Caldas.
BMC Med, 2013 Jun 27; 11. PMID: 23800190    Free PMC article.
Treatment of breast cancer in young women: do we need more aggressive therapies?
Giuseppe Cancello, Emilia Montagna.
J Thorac Dis, 2013 Jul 03; 5 Suppl 1. PMID: 23819027    Free PMC article.
Relapsed triple-negative breast cancer: challenges and treatment strategies.
Valentina Guarneri, Maria Vittoria Dieci, Pierfranco Conte.
Drugs, 2013 Jul 12; 73(12). PMID: 23842749
MUC1 is expressed at high frequency in early-stage basal-like triple-negative breast cancer.
Alan Siroy, Fadi W Abdul-Karim, +4 authors, Joseph Baar.
Hum Pathol, 2013 Jul 13; 44(10). PMID: 23845471    Free PMC article.
Chemotherapy dosing in overweight and obese patients with cancer.
Gary H Lyman, Alex Sparreboom.
Nat Rev Clin Oncol, 2013 Jul 17; 10(8). PMID: 23856744
A case of synchronous bilateral breast cancer with different pathological responses to neoadjuvant chemotherapy with different biological character.
Mitsuhiro Hayashi, Yutaka Yamamoto, Noboru Takata, Hirotaka Iwase.
Springerplus, 2013 Jul 23; 2(1). PMID: 23875131    Free PMC article.
Luminal breast cancer: from biology to treatment.
Michail Ignatiadis, Christos Sotiriou.
Nat Rev Clin Oncol, 2013 Jul 25; 10(9). PMID: 23881035
Patterns of Recurrence and outcome according to breast cancer subtypes in lymph node-negative disease: results from international breast cancer study group trials VIII and IX.
Otto Metzger-Filho, Zhuoxin Sun, +8 authors, Fatima Cardoso.
J Clin Oncol, 2013 Jul 31; 31(25). PMID: 23897954    Free PMC article.
Highly Cited.
Toxicity Analysis in the ADEBAR Trial: Sequential Anthracycline-Taxane Therapy Compared with FEC120 for the Adjuvant Treatment of High-Risk Breast Cancer.
Alexandra Schönherr, Viktoria Aivazova-Fuchs, +14 authors, Brigitte Rack.
Breast Care (Basel), 2013 Aug 02; 7(4). PMID: 23904831    Free PMC article.
A gene signature for late distant metastasis in breast cancer identifies a potential mechanism of late recurrences.
Lorenza Mittempergher, Mahasti Saghatchian, +9 authors, Laura J van't Veer.
Mol Oncol, 2013 Aug 06; 7(5). PMID: 23910573    Free PMC article.
Black-white differences in breast cancer outcomes among older Medicare beneficiaries: does systemic treatment matter?
Jeanne S Mandelblatt, Vanessa B Sheppard, Alfred I Neugut.
JAMA, 2013 Aug 07; 310(4). PMID: 23917286    Free PMC article.
Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013.
A Goldhirsch, E P Winer, +5 authors, Panel members.
Ann Oncol, 2013 Aug 07; 24(9). PMID: 23917950    Free PMC article.
Highly Cited.
Ixabepilone administered weekly or every three weeks in HER2-negative metastatic breast cancer patients; a randomized non-comparative phase II trial.
George Fountzilas, Vassiliki Kotoula, +13 authors, Dimosthenis V Skarlos.
PLoS One, 2013 Aug 13; 8(7). PMID: 23935969    Free PMC article.
Definitive results of a phase III adjuvant trial comparing three chemotherapy regimens in women with operable, node-positive breast cancer: the NSABP B-38 trial.
Sandra M Swain, Gong Tang, +17 authors, Norman Wolmark.
J Clin Oncol, 2013 Aug 14; 31(26). PMID: 23940225    Free PMC article.
Cost-effectiveness of an aprepitant regimen for prevention of chemotherapy-induced nausea and vomiting in patients with breast cancer in the UK.
Samantha Humphreys, James Pellissier, Alison Jones.
Cancer Manag Res, 2013 Aug 21; 5. PMID: 23950658    Free PMC article.
Is Age-targeted full-field digital mammography screening cost-effective in emerging countries? A micro simulation model.
Fabiano Hahn Souza, Carísi Anne Polanczyk.
Springerplus, 2013 Aug 21; 2. PMID: 23961428    Free PMC article.
The impact of the Oncotype Dx breast cancer assay in clinical practice: a systematic review and meta-analysis.
Josh J Carlson, Joshua A Roth.
Breast Cancer Res Treat, 2013 Aug 27; 141(1). PMID: 23974828    Free PMC article.
Highly Cited. Systematic Review.
SEOM clinical guidelines for the systemic treatment of early breast cancer 2013.
S Del Barco, E Ciruelos, +3 authors, SEOM.
Clin Transl Oncol, 2013 Aug 28; 15(12). PMID: 23979909
Marital status and survival in patients with cancer.
Ayal A Aizer, Ming-Hui Chen, +9 authors, Paul L Nguyen.
J Clin Oncol, 2013 Sep 26; 31(31). PMID: 24062405    Free PMC article.
Highly Cited.
Breast cancer management in the elderly.
M Luque, F Arranz, +9 authors, Y Fernández.
Clin Transl Oncol, 2013 Oct 03; 16(4). PMID: 24085574
Benefit risk assessment and update on the use of docetaxel in the management of breast cancer.
Scheryll Alken, Catherine M Kelly.
Cancer Manag Res, 2013 Oct 22; 5. PMID: 24143122    Free PMC article.
Neoadjuvant chemotherapy adaptation and serial MRI response monitoring in ER-positive HER2-negative breast cancer.
L S Rigter, C E Loo, +11 authors, S Rodenhuis.
Br J Cancer, 2013 Oct 24; 109(12). PMID: 24149178    Free PMC article.
Adjuvant radiotherapy of regional lymph nodes in breast cancer - a meta-analysis of randomized trials.
Wilfried Budach, Kai Kammers, Edwin Boelke, Christiane Matuschek.
Radiat Oncol, 2013 Nov 15; 8. PMID: 24225206    Free PMC article.
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.
Suzanne A Eccles, Eric O Aboagye, +84 authors, Alastair M Thompson.
Breast Cancer Res, 2013 Nov 30; 15(5). PMID: 24286369    Free PMC article.
Highly Cited. Review.
Preferences for oral versus intravenous adjuvant chemotherapy among early breast cancer patients.
Makoto Ishitobi, Kazuyo Shibuya, +2 authors, Hideo Inaji.
Patient Prefer Adherence, 2013 Dec 03; 7. PMID: 24293991    Free PMC article.
Characteristics and clinical outcome of T1 breast cancer: a multicenter retrospective cohort study.
G Houvenaeghel, A Goncalves, +20 authors, B Esterni.
Ann Oncol, 2014 Jan 09; 25(3). PMID: 24399079    Free PMC article.
AGO Recommendations for Diagnosis and Treatment of Patients with Early Breast Cancer: Update 2013.
Anton Scharl, Christoph Thomssen, Nadia Harbeck, Volkmar Müller.
Breast Care (Basel), 2014 Jan 15; 8(3). PMID: 24415966    Free PMC article.
Next-generation sequencing of disseminated tumor cells.
Elen K Møller, Parveen Kumar, +12 authors, Vessela N Kristensen.
Front Oncol, 2014 Jan 16; 3. PMID: 24427740    Free PMC article.
Chemotherapy for isolated locoregional recurrence of breast cancer (CALOR): a randomised trial.
Stefan Aebi, Shari Gelber, +18 authors, CALOR investigators.
Lancet Oncol, 2014 Jan 21; 15(2). PMID: 24439313    Free PMC article.
Long-term prognosis of early-onset breast cancer in a population-based cohort with a known BRCA1/2 mutation status.
Martin P Nilsson, Linda Hartman, +3 authors, Niklas Loman.
Breast Cancer Res Treat, 2014 Jan 31; 144(1). PMID: 24477976    Free PMC article.
Estrogen receptor (ER) α mutations in breast cancer: hidden in plain sight.
Suzanne A W Fuqua, Guowei Gu, Yassine Rechoum.
Breast Cancer Res Treat, 2014 Feb 04; 144(1). PMID: 24487689    Free PMC article.
Manganese superoxide dismutase and breast cancer recurrence: a Danish clinical registry-based case-control study, and a meta-analysis.
Deirdre P Cronin-Fenton, Mariann Christensen, +7 authors, Stephen Hamilton-Dutoit.
PLoS One, 2014 Feb 06; 9(1). PMID: 24498107    Free PMC article.
Prediction of benefit from chemotherapy in ER-positive/HER2-negative breast cancer--a problem still to be solved.
M Schmidt, M Untch.
Ann Oncol, 2014 Feb 07; 25(3). PMID: 24500980    Free PMC article.
Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials.
EBCTCG (Early Breast Cancer Trialists' Collaborative Group), P McGale, +11 authors, S Darby.
Lancet, 2014 Mar 25; 383(9935). PMID: 24656685    Free PMC article.
Highly Cited.
Management of primary metastatic breast cancer in elderly patients--an international comparison of oncogeriatric versus standard care.
Willemien van de Water, Esther Bastiaannet, +6 authors, Martine Extermann.
J Geriatr Oncol, 2014 Mar 26; 5(3). PMID: 24661770    Free PMC article.
Effect of cytotoxic chemotherapy on markers of molecular age in patients with breast cancer.
Hanna K Sanoff, Allison M Deal, +15 authors, Hyman B Muss.
J Natl Cancer Inst, 2014 Apr 01; 106(4). PMID: 24681605    Free PMC article.
Highly Cited.
Treatment patterns and clinical outcomes for patients with de novo versus recurrent HER2-positive metastatic breast cancer.
Denise A Yardley, Peter A Kaufman, +6 authors, Debu Tripathy.
Breast Cancer Res Treat, 2014 Apr 08; 145(3). PMID: 24706168    Free PMC article.
Age Does not Matter, Biology of Both Cancer and Patient Does.
Matti S Aapro.
Breast Care (Basel), 2012 Dec 01; 7(6). PMID: 24715823    Free PMC article.
Present status of adjuvant chemotherapy for elderly breast cancer patients.
Sibylle Loibl, Mattea Reinisch.
Breast Care (Basel), 2012 Dec 01; 7(6). PMID: 24715824    Free PMC article.
Systematic review of breast cancer related lymphoedema: making a balanced decision to perform an axillary clearance.
M Göker, N Devoogdt, +4 authors, E T M de Jonge.
Facts Views Vis Obgyn, 2013 Jan 01; 5(2). PMID: 24753936    Free PMC article.
Interdisciplinary GoR level III Guidelines for the Diagnosis, Therapy and Follow-up Care of Breast Cancer: Short version - AWMF Registry No.: 032-045OL AWMF-Register-Nummer: 032-045OL - Kurzversion 3.0, Juli 2012.
R Kreienberg, U-S Albert, +3 authors, A Wöckel.
Geburtshilfe Frauenheilkd, 2014 Apr 29; 73(6). PMID: 24771925    Free PMC article.
Multigene Assays for Classification, Prognosis, and Prediction in Breast Cancer: a Critical Review on the Background and Clinical Utility.
P Sinn, S Aulmann, +6 authors, A Schneeweiss.
Geburtshilfe Frauenheilkd, 2014 Apr 29; 73(9). PMID: 24771945    Free PMC article.
Anthracycline-based induction chemotherapy followed by concurrent cyclophosphamide, methotrexate and 5-fluorouracil and radiation therapy in surgically resected axillary node-positive breast cancer.
Francesco Recchia, Giampiero Candeloro, +6 authors, Silvio Rea.
Mol Clin Oncol, 2014 Apr 29; 2(3). PMID: 24772320    Free PMC article.
Cognitive impairment in older patients with breast cancer before systemic therapy: is there an interaction between cancer and comorbidity?
Jeanne S Mandelblatt, Robert A Stern, +16 authors, Tim Ahles.
J Clin Oncol, 2014 May 21; 32(18). PMID: 24841981    Free PMC article.
Predictive and prognostic value of the 21-gene recurrence score in hormone receptor-positive, node-positive breast cancer.
Adam M Brufsky.
Am J Clin Oncol, 2014 May 24; 37(4). PMID: 24853663    Free PMC article.
Systematic Review.
Evaluation of microRNA-10b prognostic significance in a prospective cohort of breast cancer patients.
Paola Parrella, Raffaela Barbano, +15 authors, Vito Michele Fazio.
Mol Cancer, 2014 Jun 06; 13. PMID: 24897960    Free PMC article.
Presentation and management of docetaxel-related adverse effects in patients with breast cancer.
Maria Y Ho, John R Mackey.
Cancer Manag Res, 2014 Jun 07; 6. PMID: 24904223    Free PMC article.
The effect of metformin on breast cancer outcomes in patients with type 2 diabetes.
Bridget A Oppong, Lindsay A Pharmer, +4 authors, Tari A King.
Cancer Med, 2014 Jun 20; 3(4). PMID: 24944108    Free PMC article.
Outcome of Breast Cancer Patients Treated outside of Clinical Trials.
Nagi S El Saghir, Hussein A Assi, +5 authors, Toufic A Eid.
J Cancer, 2014 Jun 25; 5(6). PMID: 24959302    Free PMC article.
BCL-2, topoisomerase IIα, microvessel density and prognosis of early advanced breast cancer patients after adjuvant anthracycline-based chemotherapy.
Beata Biesaga, Joanna Niemiec, Marek Ziobro.
J Cancer Res Clin Oncol, 2014 Jul 10; 140(12). PMID: 25005788    Free PMC article.
Dose-dense sequential adjuvant chemotherapy followed, as indicated, by trastuzumab for one year in patients with early breast cancer: first report at 5-year median follow-up of a Hellenic Cooperative Oncology Group randomized phase III trial.
George Fountzilas, Urania Dafni, +20 authors, Meletios-Athanassios Dimopoulos.
BMC Cancer, 2014 Jul 17; 14. PMID: 25026897    Free PMC article.
Diagnostic tests based on gene expression profile in breast cancer: from background to clinical use.
Laura Zanotti, Alberto Bottini, +2 authors, Maria Rosa Cappelletti.
Tumour Biol, 2014 Jul 23; 35(9). PMID: 25048969
Tamoxifen plus tegafur-uracil (TUFT) versus tamoxifen plus Adriamycin (doxorubicin) and cyclophosphamide (ACT) as adjuvant therapy to treat node-positive premenopausal breast cancer (PreMBC): results of Japan Clinical Oncology Group Study 9404.
Tadahiko Shien, Hiroji Iwata, +8 authors, Haruhiko Fukuda.
Cancer Chemother Pharmacol, 2014 Jul 25; 74(3). PMID: 25055938    Free PMC article.
What is the quality of economic evaluations of non-drug therapies? A systematic review and critical appraisal of economic evaluations of radiotherapy for cancer.
M Barbieri, H L A Weatherly, +8 authors, M Powell.
Appl Health Econ Health Policy, 2014 Jul 26; 12(5). PMID: 25060829    Free PMC article.
Systematic Review.
Comparison of patient reported quality of life and impact of treatment side effects experienced with a taxane-containing regimen and standard anthracycline based chemotherapy for early breast cancer: 6 year results from the UK TACT trial (CRUK/01/001).
E Hall, D Cameron, +6 authors, TACT Trial Investigators.
Eur J Cancer, 2014 Jul 30; 50(14). PMID: 25065293    Free PMC article.
Adjuvant chemotherapy in breast cancer: To use or not to use, the anthracyclines.
Jennifer A Crozier, Abhisek Swaika, Alvaro Moreno-Aspitia.
World J Clin Oncol, 2014 Aug 13; 5(3). PMID: 25114866    Free PMC article.
Measuring decision quality: psychometric evaluation of a new instrument for breast cancer chemotherapy.
Clara N Lee, Matthew H Wetschler, +4 authors, Karen R Sepucha.
BMC Med Inform Decis Mak, 2014 Aug 22; 14. PMID: 25142035    Free PMC article.
Chemotherapy in early breast cancer: when, how and which one?
Marcus Schmidt.
Breast Care (Basel), 2014 Sep 02; 9(3). PMID: 25177256    Free PMC article.
Weibull regression with Bayesian variable selection to identify prognostic tumour markers of breast cancer survival.
P J Newcombe, H Raza Ali, +4 authors, S Richardson.
Stat Methods Med Res, 2014 Sep 07; 26(1). PMID: 25193065    Free PMC article.
Integrative oncology: really the best of both worlds?
David H Gorski.
Nat Rev Cancer, 2014 Sep 19; 14(10). PMID: 25230880
Both carboplatin and bevacizumab improve pathological complete remission rate in neoadjuvant treatment of triple negative breast cancer: a meta-analysis.
Xiao-song Chen, Ying Yuan, +3 authors, Kun-wei Shen.
PLoS One, 2014 Sep 24; 9(9). PMID: 25247558    Free PMC article.
Fertility preservation in women with cancer.
Michel De Vos, Johan Smitz, Teresa K Woodruff.
Lancet, 2014 Oct 07; 384(9950). PMID: 25283571    Free PMC article.
Highly Cited. Review.
PTK7 as a potential prognostic and predictive marker of response to adjuvant chemotherapy in breast cancer patients, and resistance to anthracycline drugs.
Beyhan Ataseven, Angela Gunesch, +5 authors, Nadia Harbeck.
Onco Targets Ther, 2014 Oct 23; 7. PMID: 25336969    Free PMC article.
MicroRNA-185 inhibits proliferation by targeting c-Met in human breast cancer cells.
Peifen Fu, Feiya DU, +2 authors, Yu Liu.
Exp Ther Med, 2014 Nov 06; 8(6). PMID: 25371748    Free PMC article.
Chromosome 17 centromere duplication and responsiveness to anthracycline-based neoadjuvant chemotherapy in breast cancer.
Ariadna Tibau, Laura López-Vilaró, +9 authors, Daniel Escuin.
Neoplasia, 2014 Nov 08; 16(10). PMID: 25379022    Free PMC article.
Current treatment of early breast cancer: adjuvant and neoadjuvant therapy.
Elizabeth Miller, Hee Jin Lee, +3 authors, Bora Lim.
F1000Res, 2014 Nov 18; 3. PMID: 25400908    Free PMC article.
Cost-effectiveness analysis of prognostic gene expression signature-based stratification of early breast cancer patients.
Patricia R Blank, Martin Filipits, +11 authors, Michael Gnant.
Pharmacoeconomics, 2014 Nov 19; 33(2). PMID: 25404424    Free PMC article.
Suppression of invasion and metastasis of triple-negative breast cancer lines by pharmacological or genetic inhibition of slug activity.
Giovanna Ferrari-Amorotti, Claudia Chiodoni, +9 authors, Bruno Calabretta.
Neoplasia, 2014 Dec 17; 16(12). PMID: 25499218    Free PMC article.
Risk of marrow neoplasms after adjuvant breast cancer therapy: the national comprehensive cancer network experience.
Antonio C Wolff, Amanda L Blackford, +10 authors, Judith E Karp.
J Clin Oncol, 2014 Dec 24; 33(4). PMID: 25534386    Free PMC article.
Phase II study of paclitaxel given once per week along with trastuzumab and pertuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer.
Chau Dang, Neil Iyengar, +17 authors, Clifford Hudis.
J Clin Oncol, 2014 Dec 31; 33(5). PMID: 25547504    Free PMC article.
Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer.
Sara M Tolaney, William T Barry, +16 authors, Eric P Winer.
N Engl J Med, 2015 Jan 08; 372(2). PMID: 25564897    Free PMC article.
Highly Cited.
Survivorship in untreated breast cancer patients.
Carlos M Galmarini, Olivier Tredan, Felipe C Galmarini.
Med Oncol, 2015 Jan 16; 32(2). PMID: 25588926
Optimal management of breast cancer in the elderly patient: current perspectives.
Olivia Le Saux, Bertrand Ripamonti, +4 authors, Claire Falandry.
Clin Interv Aging, 2015 Jan 23; 10. PMID: 25609933    Free PMC article.
Trastuzumab induced cardiotoxicity in HER2 positive breast cancer patients attended in a tertiary hospital.
Lorena Rocha Ayres, Marília Silveira de Almeida Campos, +4 authors, Leonardo Régis Leira Pereira.
Int J Clin Pharm, 2015 Feb 01; 37(2). PMID: 25637407
Cardiac risk in the treatment of breast cancer: assessment and management.
Antonis Valachis, Cecilia Nilsson.
Breast Cancer (Dove Med Press), 2015 Feb 06; 7. PMID: 25653554    Free PMC article.
Association of CYP2D6*10, OATP1B1 A388G, and OATP1B1 T521C polymorphisms and overall survival of breast cancer patients after tamoxifen therapy.
Xuefeng Zhang, Zhichen Pu, +3 authors, Haitang Xie.
Med Sci Monit, 2015 Feb 24; 21. PMID: 25701109    Free PMC article.
Landscape of neoadjuvant therapy for breast cancer.
Tufia C Haddad, Matthew P Goetz.
Ann Surg Oncol, 2015 Mar 03; 22(5). PMID: 25727557    Free PMC article.
Ovarian stimulation in patients with breast cancer.
Elkin Muñoz, Naira González, +2 authors, Juan A García Velasco.
Ecancermedicalscience, 2015 Mar 03; 9. PMID: 25729417    Free PMC article.
The value of personalizing medicine: medical oncologists' views on gene expression profiling in breast cancer treatment.
Yvonne Bombard, Linda Rozmovits, +3 authors, Deborah A Marshall.
Oncologist, 2015 Mar 10; 20(4). PMID: 25746345    Free PMC article.
Variation in type of adjuvant chemotherapy received among patients with stage I breast cancer: A multi-institutional study.
Ines Vaz-Luis, Melissa E Hughes, +7 authors, Nancy U Lin.
Cancer, 2015 Mar 12; 121(12). PMID: 25757412    Free PMC article.
Clinical implications of circulating tumor cells of breast cancer patients: role of epithelial-mesenchymal plasticity.
Linda M McInnes, Natalie Jacobson, +3 authors, Christobel M Saunders.
Front Oncol, 2015 Mar 15; 5. PMID: 25767772    Free PMC article.
Neutrophil-guided dosing of anthracycline-cyclophosphamide-containing chemotherapy in patients with breast cancer: a feasibility study.
Jan C Drooger, Johanna M van Pelt-Sprangers, +2 authors, Felix E de Jongh.
Med Oncol, 2015 Mar 17; 32(4). PMID: 25772511    Free PMC article.
Ki67--no evidence for its use in node-positive breast cancer.
Fabrice Andre, Monica Arnedos, +2 authors, Suzette Delaloge.
Nat Rev Clin Oncol, 2015 Mar 18; 12(5). PMID: 25781576
Postmastectomy radiotherapy improves disease-free survival of high risk of locoregional recurrence breast cancer patients with T1-2 and 1 to 3 positive nodes.
Zhen-Yu He, San-Gang Wu, +4 authors, Jia-Yuan Sun.
PLoS One, 2015 Mar 18; 10(3). PMID: 25781605    Free PMC article.
In the era of genomics, should tumor size be reconsidered as a criterion for neoadjuvant chemotherapy?
Xavier Pivot, Laura Mansi, +14 authors, Christian Villanueva.
Oncologist, 2015 Mar 22; 20(4). PMID: 25795632    Free PMC article.
Flubendazole, FDA-approved anthelmintic, targets breast cancer stem-like cells.
Zhi-Jie Hou, Xi Luo, +12 authors, Quentin Liu.
Oncotarget, 2015 Mar 27; 6(8). PMID: 25811972    Free PMC article.
An open-label, randomized, multicenter dose-finding study of once-per-cycle pegfilgrastim versus daily filgrastim in Chinese breast cancer patients receiving TAC chemotherapy.
Wei Zhang, Zhiwei Jiang, +2 authors, Jielai Xia.
Med Oncol, 2015 Mar 31; 32(5). PMID: 25820754
Optimal systemic therapy for early breast cancer in women: a clinical practice guideline.
A Eisen, G G Fletcher, +5 authors, members of the Early Breast Cancer Systemic Therapy Consensus Panel.
Curr Oncol, 2015 Apr 08; 22(Suppl 1). PMID: 25848340    Free PMC article.
Adjuvant chemotherapy for early female breast cancer: a systematic review of the evidence for the 2014 Cancer Care Ontario systemic therapy guideline.
S Gandhi, G G Fletcher, +4 authors, M E Trudeau.
Curr Oncol, 2015 Apr 08; 22(Suppl 1). PMID: 25848343    Free PMC article.
Adjuvant endocrine therapy for early breast cancer: a systematic review of the evidence for the 2014 Cancer Care Ontario systemic therapy guideline.
O C Freedman, G G Fletcher, +4 authors, A Eisen.
Curr Oncol, 2015 Apr 08; 22(Suppl 1). PMID: 25848344    Free PMC article.
Biomarkers of fatigue related to adjuvant chemotherapy for breast cancer: evaluation of plasma and lymphocyte expression.
Felipe M Cruz, Bruna A Munhoz, +6 authors, Auro Del Giglio.
Clin Transl Med, 2015 Apr 09; 4. PMID: 25852820    Free PMC article.
Tailoring therapies--improving the management of early breast cancer: St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2015.
A S Coates, E P Winer, +6 authors, Panel Members.
Ann Oncol, 2015 May 06; 26(8). PMID: 25939896    Free PMC article.
Highly Cited.
Effect of age on drug metabolism in women with breast cancer.
Jasmeet C Singh, Stuart M Lichtman.
Expert Opin Drug Metab Toxicol, 2015 May 06; 11(5). PMID: 25940027    Free PMC article.
Impact of adjuvant taxane-based chemotherapy on development of breast cancer-related lymphedema: results from a large prospective cohort.
Meyha N Swaroop, Chantal M Ferguson, +8 authors, Alphonse G Taghian.
Breast Cancer Res Treat, 2015 May 06; 151(2). PMID: 25940996    Free PMC article.
Concomitant inactivation of the p53- and pRB- functional pathways predicts resistance to DNA damaging drugs in breast cancer in vivo.
Stian Knappskog, Elisabet O Berge, +16 authors, Per E Lønning.
Mol Oncol, 2015 May 26; 9(8). PMID: 26004085    Free PMC article.
Informed decision-making and breast cancer screening.
P D Sasieni, R A Smith, S W Duffy.
J Med Screen, 2015 May 29; 22(4). PMID: 26018778    Free PMC article.
Adjuvant Metronomic CMF in a Contemporary Breast Cancer Cohort: What's Old Is New.
Eunpi Cho, Ann K Schwemm, +7 authors, Vijayakrishna K Gadi.
Clin Breast Cancer, 2015 May 31; 15(5). PMID: 26025883    Free PMC article.
Long-Term Follow-Up of the E1199 Phase III Trial Evaluating the Role of Taxane and Schedule in Operable Breast Cancer.
Joseph A Sparano, Fengmin Zhao, +7 authors, Nancy E Davidson.
J Clin Oncol, 2015 Jun 17; 33(21). PMID: 26077235    Free PMC article.
Is febrile neutropenia prophylaxis with granulocyte-colony stimulating factors economically justified for adjuvant TC chemotherapy in breast cancer?
Chris Skedgel, Daniel Rayson, Tallal Younis.
Support Care Cancer, 2015 Jun 18; 24(1). PMID: 26081595
Viewpoint: It is time to reconsider policy for population-based mammography screening.
Anne J Kearney.
J Public Health Policy, 2015 Jun 26; 36(3). PMID: 26108575
Treatment Considerations for the Management of Patients With Hormone Receptor-Positive Metastatic Breast Cancer.
Constance Visovsky.
J Adv Pract Oncol, 2015 Jun 27; 5(5). PMID: 26114012    Free PMC article.
Adjuvant Systemic Therapy in Older Breast Cancer Women: Can We Optimize the Level of Care?
Anna Rachelle Mislang, Laura Biganzoli.
Cancers (Basel), 2015 Jul 08; 7(3). PMID: 26151681    Free PMC article.
Association of human epidermal growth factor receptor 2 status with ipsilateral breast tumor recurrence and resistance to endocrine therapy.
Makoto Ishitobi, Mizuho Shiba, +2 authors, Yasuhiro Tamaki.
Mol Clin Oncol, 2015 Jul 15; 3(4). PMID: 26171193    Free PMC article.
Clinical utility of the IHC4+C score in oestrogen receptor-positive early breast cancer: a prospective decision impact study.
B Yeo, L Zabaglo, +3 authors, M Dowsett.
Br J Cancer, 2015 Jul 17; 113(3). PMID: 26180920    Free PMC article.
Impact of Adjuvant Chemotherapy on Breast Cancer Survival: A Real-World Population.
Lea Rossi, Denise Stevens, +5 authors, Roman Rouzier.
PLoS One, 2015 Jul 28; 10(7). PMID: 26214853    Free PMC article.
Optimal approach in early breast cancer: Adjuvant and neoadjuvant treatment.
J Ribeiro, B Sousa, F Cardoso.
EJC Suppl, 2013 Sep 01; 11(2). PMID: 26217109    Free PMC article.
Prevention and Treatment of Bone Metastases in Breast Cancer.
Ripamonti Carla, Trippa Fabio, Barone Gloria, Maranzano Ernesto.
J Clin Med, 2013 Jan 01; 2(3). PMID: 26237068    Free PMC article.
Prevention of Bone Metastases in Breast Cancer Patients. Therapeutic Perspectives.
Philippe Beuzeboc, Suzy Scholl.
J Clin Med, 2014 Jan 01; 3(2). PMID: 26237389    Free PMC article.
The Right Treatment for the Right Patient - Personalised Treatment of Breast Cancer.
A Scharl, T Kühn, T Papathemelis, A Salterberg.
Geburtshilfe Frauenheilkd, 2015 Aug 11; 75(7). PMID: 26257405    Free PMC article.
Progress in adjuvant chemotherapy for breast cancer: an overview.
Jesus Anampa, Della Makower, Joseph A Sparano.
BMC Med, 2015 Aug 19; 13. PMID: 26278220    Free PMC article.
Highly Cited. Review.
TLE3 is not a predictive biomarker for taxane sensitivity in the NCIC CTG MA.21 clinical trial.
J M S Bartlett, T O Nielsen, +10 authors, NCIC CTG.
Br J Cancer, 2015 Aug 19; 113(5). PMID: 26284338    Free PMC article.
Do Recent Advances in Diagnostic and Therapeutic Procedures Negate the Benefit of Postmastectomy Radiotherapy in N1 Patients With a Low Risk of Locoregional Recurrence?
Jee Suk Chang, Jeongshim Lee, +7 authors, Yong Bae Kim.
Medicine (Baltimore), 2015 Aug 20; 94(33). PMID: 26287410    Free PMC article.
Long term side effects of adjuvant chemotherapy in patients with early breast cancer.
Jessica J Tao, Kala Visvanathan, Antonio C Wolff.
Breast, 2015 Aug 25; 24 Suppl 2. PMID: 26299406    Free PMC article.
Breast cancer: The debate over post-mastectomy radiotherapy should continue.
Caspian Oliai, Sara A Hurvitz.
Nat Rev Clin Oncol, 2015 Sep 02; 12(10). PMID: 26323387
Neoadjuvant chemotherapy and trastuzumab versus neoadjuvant chemotherapy followed by post-operative trastuzumab for patients with HER2-positive breast cancer.
Carlo Palmieri, Iain Rj Macpherson, +14 authors, Sacha J Howell.
Oncotarget, 2015 Sep 04; 7(11). PMID: 26334099    Free PMC article.
Port catheter versus peripherally inserted central catheter for postoperative chemotherapy in early breast cancer: a retrospective analysis of 448 patients.
L Lefebvre, E Noyon, +9 authors, F Clatot.
Support Care Cancer, 2015 Sep 08; 24(3). PMID: 26342484
Prognostic effect analysis of molecular subtype on young breast cancer patients.
Hong-Liang Chen, Ang Ding, Fu-Wen Wang.
Chin J Cancer Res, 2015 Sep 12; 27(4). PMID: 26361413    Free PMC article.
Breast cancer cells respond differently to docetaxel depending on their phenotype and on survivin upregulation.
Francesca De Iuliis, Gerardo Salerno, +7 authors, Susanna Scarpa.
Tumour Biol, 2015 Sep 24; 37(2). PMID: 26392111
Prospective Validation of a 21-Gene Expression Assay in Breast Cancer.
Joseph A Sparano, Robert J Gray, +28 authors, George W Sledge.
N Engl J Med, 2015 Sep 29; 373(21). PMID: 26412349    Free PMC article.
Highly Cited.
Breast Cancer: Conventional Diagnosis and Treatment Modalities and Recent Patents and Technologies.
Mohamed I Nounou, Fatema ElAmrawy, +3 authors, Hussaini Syed-Sha-Qhattal.
Breast Cancer (Auckl), 2015 Oct 16; 9(Suppl 2). PMID: 26462242    Free PMC article.
Immunohistochemical subtypes predict the clinical outcome in high-risk node-negative breast cancer patients treated with adjuvant FEC regimen: results of a single-center retrospective study.
S Rahal, J M Boher, +12 authors, A Gonçalves.
BMC Cancer, 2015 Oct 16; 15. PMID: 26466893    Free PMC article.
Early-Stage Breast Cancer in the Elderly: Confronting an Old Clinical Problem.
Fotinos-Ioannis D Dimitrakopoulos, Anastasia Kottorou, +2 authors, Haralabos P Kalofonos.
J Breast Cancer, 2015 Oct 17; 18(3). PMID: 26472970    Free PMC article.
Evaluation of the Survival Benefit of Different Chemotherapy Regimens in Patients with T1-2N0 Triple-Negative Breast Cancer.
Hyun-Ah Kim, Min-Ki Seong, +6 authors, Korea Breast Cancer Society.
J Breast Cancer, 2015 Oct 17; 18(3). PMID: 26472978    Free PMC article.
SEOM clinical guidelines in early-stage breast cancer 2015.
J A Garcia-Saenz, B Bermejo, +7 authors, E Ciruelos.
Clin Transl Oncol, 2015 Oct 27; 17(12). PMID: 26497356    Free PMC article.
FN14 and GRP94 expression are prognostic/predictive biomarkers of brain metastasis outcome that open up new therapeutic strategies.
Antonio Martínez-Aranda, Vanessa Hernández, +16 authors, Angels Sierra.
Oncotarget, 2015 Oct 27; 6(42). PMID: 26497551    Free PMC article.
A genome-wide association study identifies WT1 variant with better response to 5-fluorouracil, pirarubicin and cyclophosphamide neoadjuvant chemotherapy in breast cancer patients.
Lina Wu, Lu Yao, +8 authors, Yuntao Xie.
Oncotarget, 2015 Nov 18; 7(4). PMID: 26573232    Free PMC article.
Proposing Essential Medicines to Treat Cancer: Methodologies, Processes, and Outcomes.
Lawrence N Shulman, Claire M Wagner, +6 authors, Nicola Magrini.
J Clin Oncol, 2015 Nov 19; 34(1). PMID: 26578613    Free PMC article.
Are adjuvant bisphosphonates now standard of care of women with early stage breast cancer? A debate from the Canadian Bone and the Oncologist New Updates meeting.
Carmel Jacobs, Eitan Amir, +2 authors, Mark Clemons.
J Bone Oncol, 2015 Nov 19; 4(2). PMID: 26579489    Free PMC article.
Adjuvant Chemotherapy Use and Health Care Costs After Introduction of Genomic Testing in Breast Cancer.
Andrew J Epstein, Yu-Ning Wong, +6 authors, Peter W Groeneveld.
J Clin Oncol, 2015 Nov 26; 33(36). PMID: 26598749    Free PMC article.
The Practicability of a Novel Prognostic Index (PI) Model and Comparison with Nottingham Prognostic Index (NPI) in Stage I-III Breast Cancer Patients Undergoing Surgical Treatment.
Jiahuai Wen, Feng Ye, +4 authors, Xiaoming Xie.
PLoS One, 2015 Nov 26; 10(11). PMID: 26600129    Free PMC article.
Biomarkers in Breast Cancer - An Update.
M Schmidt, P A Fasching, M W Beckmann, H Kölbl.
Geburtshilfe Frauenheilkd, 2012 Sep 01; 72(9). PMID: 26640290    Free PMC article.
Recommendations from the EGAPP Working Group: does the use of Oncotype DX tumor gene expression profiling to guide treatment decisions improve outcomes in patients with breast cancer?
Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group*.
Genet Med, 2015 Dec 19; 18(8). PMID: 26681310
The search for optimal cutoff points for apoptosis and proliferation rate in prognostification of early stage breast cancer patients treated with anthracyclines in adjuvant settings.
Beata Biesaga, Joanna Niemiec, +2 authors, Marek Ziobro.
Tumour Biol, 2015 Dec 22; 37(6). PMID: 26687650
Knockdown of heme oxygenase-1 promotes apoptosis and autophagy and enhances the cytotoxicity of doxorubicin in breast cancer cells.
Xiao-Feng Zhu, Wen Li, +6 authors, Shen-Ming Wang.
Oncol Lett, 2016 Jan 02; 10(5). PMID: 26722274    Free PMC article.
The Effect of Treatment Advances on the Mortality Results of Breast Cancer Screening Trials: A Microsimulation Model.
Jeanette Birnbaum, Vijayakrishna K Gadi, Elan Markowitz, Ruth Etzioni.
Ann Intern Med, 2016 Jan 13; 164(4). PMID: 26756332    Free PMC article.
Collaborative Modeling of the Benefits and Harms Associated With Different U.S. Breast Cancer Screening Strategies.
Jeanne S Mandelblatt, Natasha K Stout, +25 authors, Kathleen A Cronin.
Ann Intern Med, 2016 Jan 13; 164(4). PMID: 26756606    Free PMC article.
Highly Cited.
Efficacy of chemotherapy after hormone therapy for hormone receptor-positive metastatic breast cancer.
Ryutaro Mori, Yasuko Nagao.
SAGE Open Med, 2014 Jan 01; 2. PMID: 26770749    Free PMC article.
Annual Hazard Rates of Recurrence for Breast Cancer During 24 Years of Follow-Up: Results From the International Breast Cancer Study Group Trials I to V.
Marco Colleoni, Zhuoxin Sun, +8 authors, Aron Goldhirsch.
J Clin Oncol, 2016 Jan 21; 34(9). PMID: 26786933    Free PMC article.
Highly Cited.
Pharmacogenetics driving personalized medicine: analysis of genetic polymorphisms related to breast cancer medications in Italian isolated populations.
Massimiliano Cocca, Davide Bedognetti, +2 authors, Giorgia Girotto.
J Transl Med, 2016 Jan 24; 14. PMID: 26801900    Free PMC article.
Disparate Response to Methotrexate in Stem Versus Non-Stem Cells.
Olivia S Beane, Louise E O Darling, Vera C Fonseca, Eric M Darling.
Stem Cell Rev Rep, 2016 Jan 28; 12(3). PMID: 26815725    Free PMC article.
Neoadjuvant endocrine therapy in breast cancer: current role and future perspectives.
Romualdo Barroso-Sousa, Danilo D A Fonseca Reis Silva, Joao Victor Machado Alessi, Max Senna Mano.
Ecancermedicalscience, 2016 Jan 30; 10. PMID: 26823678    Free PMC article.
Fertility Preservation Options for Men and Women With Cancer.
Malgorzata E Skaznik-Wikiel, Sara Babcock Gilbert, Randall B Meacham, Laxmi A Kondapalli.
Rev Urol, 2016 Feb 04; 17(4). PMID: 26839518    Free PMC article.
Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline.
Lyndsay N Harris, Nofisat Ismaila, +11 authors, American Society of Clinical Oncology.
J Clin Oncol, 2016 Feb 10; 34(10). PMID: 26858339    Free PMC article.
Highly Cited. Review.
Targeted therapies with companion diagnostics in the management of breast cancer: current perspectives.
Meagan B Myers.
Pharmgenomics Pers Med, 2016 Feb 10; 9. PMID: 26858530    Free PMC article.
Comparison of toxicity profile and tolerability between two standard of care paclitaxel-based adjuvant chemotherapy regimens in breast cancer.
Mohamed Alsharedi, Todd Gress, +2 authors, Maria Tria Tirona.
Med Oncol, 2016 Feb 18; 33(3). PMID: 26883934
Does estrogen receptor determination affect prognosis in early stage breast cancers?
Nilufer Bulut, Kadri Altundag.
Int J Clin Exp Med, 2016 Feb 18; 8(11). PMID: 26885091    Free PMC article.
Implementation of the 21-gene recurrence score test in the United States in 2011.
Julie A Lynch, Brygida Berse, +5 authors, Andrew N Freedman.
Genet Med, 2016 Feb 19; 18(10). PMID: 26890451
Breast Carcinoma in Young Women: No Evidence of Increasing Rates of Metastatic Breast Carcinoma in a Single Tertiary Center Review.
Niamh Conlon, Jane Howard, +3 authors, Adriana D Corben.
Breast J, 2016 Mar 01; 22(3). PMID: 26923423    Free PMC article.
Difference in Restricted Mean Survival Time for Cost-Effectiveness Analysis Using Individual Patient Data Meta-Analysis: Evidence from a Case Study.
Béranger Lueza, Audrey Mauguen, +3 authors, MAR-LC Collaborative Group.
PLoS One, 2016 Mar 10; 11(3). PMID: 26960150    Free PMC article.
Breast cancer survival among young women: a review of the role of modifiable lifestyle factors.
Darren R Brenner, Nigel T Brockton, +7 authors, Christine M Friedenreich.
Cancer Causes Control, 2016 Mar 14; 27(4). PMID: 26970739    Free PMC article.
Triple-negative breast cancer exhibits a favorable response to neoadjuvant chemotherapy independent of the expression of topoisomerase IIα.
Hiroko Nogi, Ken Uchida, +7 authors, Hiroshi Takeyama.
Mol Clin Oncol, 2016 Mar 22; 4(3). PMID: 26998288    Free PMC article.
Bias and precision of methods for estimating the difference in restricted mean survival time from an individual patient data meta-analysis.
Béranger Lueza, Federico Rotolo, +2 authors, Stefan Michiels.
BMC Med Res Methodol, 2016 Mar 31; 16. PMID: 27025706    Free PMC article.
Randomised phase III trial of FEC120 vs EC-docetaxel in patients with high-risk node-positive primary breast cancer: final survival analysis of the ADEBAR study.
W Janni, N Harbeck, +9 authors, M Kiechle.
Br J Cancer, 2016 Apr 01; 114(8). PMID: 27031854    Free PMC article.
All-trans retinoic acids induce differentiation and sensitize a radioresistant breast cancer cells to chemotherapy.
Yunwen Yan, Zhen Li, +7 authors, Jiaoti Huang.
BMC Complement Altern Med, 2016 Apr 03; 16. PMID: 27036550    Free PMC article.
Prognostic Value of Chemotherapy-Induced Neutropenia at the First Cycle in Invasive Breast Cancer.
Rui-Min Ma, Chuan-Zhi Chen, +3 authors, Gui-Long Guo.
Medicine (Baltimore), 2016 Apr 05; 95(13). PMID: 27043697    Free PMC article.
A four gene signature of chromosome instability (CIN4) predicts for benefit from taxanes in the NCIC-CTG MA21 clinical trial.
Melanie Spears, Nicola Lyttle, +8 authors, John M S Bartlett.
Oncotarget, 2016 Apr 09; 7(31). PMID: 27056899    Free PMC article.
Underutilization of gene expression profiling for early-stage breast cancer in California.
Rosemary D Cress, Yingjia S Chen, +2 authors, Kenneth W Kizer.
Cancer Causes Control, 2016 Apr 22; 27(6). PMID: 27097910    Free PMC article.
Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease.
Giampaolo Bianchini, Justin M Balko, +2 authors, Luca Gianni.
Nat Rev Clin Oncol, 2016 Oct 19; 13(11). PMID: 27184417    Free PMC article.
Highly Cited. Review.
Axillary radiotherapy: an alternative treatment option for adjuvant axillary management of breast cancer.
Jie Zhang, Chuan Wang.
Sci Rep, 2016 May 24; 6. PMID: 27212421    Free PMC article.
Lung cancer screening with low-dose spiral computed tomography: evidence from a pooled analysis of two Italian randomized trials.
Maurizio Infante, Stefano Sestini, +13 authors, Ugo Pastorino.
Eur J Cancer Prev, 2016 May 26; 26(4). PMID: 27222939    Free PMC article.
The Role of the 21-Gene Recurrence Score in Breast Cancer Treatment.
Josee-Lyne Ethier, Eitan Amir.
Mol Diagn Ther, 2016 May 29; 20(4). PMID: 27235162
The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells.
Stine Ninel Hansen, Natasja Spring Ehlers, +16 authors, Ramneek Gupta.
BMC Genomics, 2016 Jun 10; 17. PMID: 27277198    Free PMC article.
Low-Dose Oral Cyclophosphamide and Methotrexate Maintenance for Hormone Receptor-Negative Early Breast Cancer: International Breast Cancer Study Group Trial 22-00.
Marco Colleoni, Kathryn P Gray, +19 authors, Aron Goldhirsch.
J Clin Oncol, 2016 Jun 22; 34(28). PMID: 27325862    Free PMC article.
Technical validation of an RT-qPCR in vitro diagnostic test system for the determination of breast cancer molecular subtypes by quantification of ERBB2, ESR1, PGR and MKI67 mRNA levels from formalin-fixed paraffin-embedded breast tumor specimens.
Mark Laible, Kornelia Schlombs, +8 authors, Ugur Sahin.
BMC Cancer, 2016 Jul 09; 16. PMID: 27389414    Free PMC article.
Should Sentinel Lymph Node Biopsy for Patients with Early Breast Cancer Be Abandoned? Not So Fast.
Quyen D Chu, Prakash Peddi.
Clin Med Insights Oncol, 2016 Jul 12; 10. PMID: 27398043    Free PMC article.
Systemic therapy for breast cancer and risk of subsequent contralateral breast cancer in the WECARE Study.
Rikke Langballe, Lene Mellemkjær, +12 authors, Jonine L Bernstein.
Breast Cancer Res, 2016 Jul 13; 18(1). PMID: 27400983    Free PMC article.
Influence of delayed initiation of adjuvant chemotherapy on breast cancer survival is subtype-dependent.
Ke-Da Yu, Lei Fan, +3 authors, Zhi-Ming Shao.
Oncotarget, 2016 Jul 23; 8(28). PMID: 27447963    Free PMC article.
Phase II studies of two different schedules of dasatinib in bone metastasis predominant metastatic breast cancer: SWOG S0622.
Anne F Schott, William E Barlow, +7 authors, Gabriel N Hortobagyi.
Breast Cancer Res Treat, 2016 Aug 01; 159(1). PMID: 27475087    Free PMC article.
Tailoring Breast Cancer Screening Intervals by Breast Density and Risk for Women Aged 50 Years or Older: Collaborative Modeling of Screening Outcomes.
Amy Trentham-Dietz, Karla Kerlikowske, +15 authors, Breast Cancer Surveillance Consortium and the Cancer Intervention and Surveillance Modeling Network.
Ann Intern Med, 2016 Aug 23; 165(10). PMID: 27548583    Free PMC article.
Operation with less adjuvant therapy for elderly breast cancer.
Akimitsu Yamada, Kazutaka Narui, +5 authors, Itaru Endo.
J Surg Res, 2016 Aug 28; 204(2). PMID: 27565077    Free PMC article.
From High-Throughput Microarray-Based Screening to Clinical Application: The Development of a Second Generation Multigene Test for Breast Cancer Prognosis.
Jan C Brase, Ralf Kronenwett, +2 authors, Marcus Schmidt.
Microarrays (Basel), 2013 Jan 01; 2(3). PMID: 27605191    Free PMC article.
Statistical controversies in clinical research: prognostic gene signatures are not (yet) useful in clinical practice.
S Michiels, N Ternès, F Rotolo.
Ann Oncol, 2016 Sep 17; 27(12). PMID: 27634691    Free PMC article.
Patterns of multidisciplinary care in the management of non-metastatic invasive breast cancer in the United States Medicare patient.
Thomas M Churilla, Brian L Egleston, +4 authors, Richard J Bleicher.
Breast Cancer Res Treat, 2016 Sep 19; 160(1). PMID: 27640196    Free PMC article.
Clinicopathological Features and Prognostic Factors Affecting Survival Outcomes in Isolated Locoregional Recurrence of Breast Cancer: Single-Institutional Series.
Min-Young Lee, Won Jin Chang, +8 authors, Yeon Hee Park.
PLoS One, 2016 Sep 21; 11(9). PMID: 27648567    Free PMC article.
Low Levels of NDRG1 in Nerve Tissue Are Predictive of Severe Paclitaxel-Induced Neuropathy.
Raghav Sundar, Anand D Jeyasekharan, +16 authors, Soo-Chin Lee.
PLoS One, 2016 Oct 08; 11(10). PMID: 27716814    Free PMC article.
Biological Subtypes and Distant Relapse Pattern in Breast Cancer Patients After Curative Surgery (Study of Anatolian Society of Medical Oncology).
Muhammet A Kaplan, Ulku Y Arslan, +21 authors, Mukremin Uysal.
Breast Care (Basel), 2016 Oct 11; 11(4). PMID: 27721711    Free PMC article.
Impact of chemotherapy on medium-term physical function and activity of older breast cancer survivors, and associated biomarkers.
Martine Extermann, Christiaan Leeuwenburgh, +7 authors, Todd M Manini.
J Geriatr Oncol, 2016 Oct 17; 8(1). PMID: 27743848    Free PMC article.
Incorporating Risk Factors to Identify the Indication of Post-mastectomy Radiotherapy in N1 Breast Cancer Treated with Optimal Systemic Therapy: A Multicenter Analysis in Korea (KROG 14-23).
Hae Jin Park, Kyung Hwan Shin, +12 authors, Suzy Kim.
Cancer Res Treat, 2016 Oct 22; 49(3). PMID: 27764904    Free PMC article.
Treatment planning and evaluation of gated radiotherapy in left-sided breast cancer patients using the CatalystTM/SentinelTM system for deep inspiration breath-hold (DIBH).
S Schönecker, F Walter, +5 authors, C Belka.
Radiat Oncol, 2016 Oct 28; 11(1). PMID: 27784326    Free PMC article.
Optimal radiation dose for patients with one to three lymph node positive breast cancer following breast-conserving surgery and anthracycline plus taxane-based chemotherapy: A retrospective multicenter analysis (KROG 1418).
Haeyoung Kim, Won Park, +18 authors, Jong-Young Lee.
Oncotarget, 2016 Oct 30; 8(1). PMID: 27793036    Free PMC article.
The global burden of women's cancers: a grand challenge in global health.
Ophira Ginsburg, Freddie Bray, +18 authors, Lesong Conteh.
Lancet, 2016 Nov 07; 389(10071). PMID: 27814965    Free PMC article.
Highly Cited. Review.
Neutrophil to lymphocyte ratio (NLR) for prediction of distant metastasis-free survival (DMFS) in early breast cancer: a propensity score-matched analysis.
Michele Orditura, Gennaro Galizia, +12 authors, Fortunato Ciardiello.
ESMO Open, 2016 Nov 16; 1(2). PMID: 27843594    Free PMC article.
Organizational Factors Affect Safety-Net Hospitals' Breast Cancer Treatment Rates.
Nina A Bickell, Alexandra DeNardis Moss, +10 authors, Ann Scheck McAlearney.
Health Serv Res, 2016 Nov 20; 52(6). PMID: 27861833    Free PMC article.
Risk of acute myeloid leukemia and myelodysplastic syndrome among older women receiving anthracycline-based adjuvant chemotherapy for breast cancer on Modern Cooperative Group Trials (Alliance A151511).
Rachel A Freedman, D K Seisler, +17 authors, H B Muss.
Breast Cancer Res Treat, 2016 Nov 21; 161(2). PMID: 27866278    Free PMC article.
Impact of Adjuvant Chemotherapy in Elderly Breast Patients in Taiwan, A Hospital-Based Study
Hsiu-Chuan Lee, Wei-Yu Chen, +5 authors, Yin- Hsun Feng.
Asian Pac J Cancer Prev, 2016 Nov 29; 17(10). PMID: 27892670    Free PMC article.
Optical redox ratio identifies metastatic potential-dependent changes in breast cancer cell metabolism.
Kinan Alhallak, Lisa G Rebello, +2 authors, Narasimhan Rajaram.
Biomed Opt Express, 2016 Nov 30; 7(11). PMID: 27895979    Free PMC article.
Hormonal Modulation of Breast Cancer Gene Expression: Implications for Intrinsic Subtyping in Premenopausal Women.
Sarah M Bernhardt, Pallave Dasari, +3 authors, Wendy V Ingman.
Front Oncol, 2016 Nov 30; 6. PMID: 27896218    Free PMC article.
SEOM Clinical Guideline for bone metastases from solid tumours (2016).
C Grávalos, C Rodríguez, +7 authors, M Martín.
Clin Transl Oncol, 2016 Nov 30; 18(12). PMID: 27896639    Free PMC article.
Sequencing-based breast cancer diagnostics as an alternative to routine biomarkers.
Mattias Rantalainen, Daniel Klevebring, +10 authors, Henrik Grönberg.
Sci Rep, 2016 Dec 03; 6. PMID: 27901097    Free PMC article.
Factors Influencing Decision-Making for or against Adjuvant and Neoadjuvant Chemotherapy in Postmenopausal Hormone Receptor-Positive Breast Cancer Patients in the EvAluate-TM Study.
Paul Gaß, Peter A Fasching, +47 authors, Christian R Löhberg.
Breast Care (Basel), 2016 Dec 07; 11(5). PMID: 27920623    Free PMC article.
BRCAness as a Biomarker for Predicting Prognosis and Response to Anthracycline-Based Adjuvant Chemotherapy for Patients with Triple-Negative Breast Cancer.
Hitomi Mori, Makoto Kubo, +11 authors, Masafumi Nakamura.
PLoS One, 2016 Dec 16; 11(12). PMID: 27977696    Free PMC article.
Stereotactic ablative body radiotherapy (SAbR) for oligometastatic cancer.
Neil B Desai, Aaron M Laine, Robert D Timmerman.
Br J Radiol, 2016 Dec 23; 90(1070). PMID: 28008774    Free PMC article.
Prognostic Impact of Elective Supraclavicular Nodal Irradiation for Patients with N1 Breast Cancer after Lumpectomy and Anthracycline Plus Taxane-Based Chemotherapy (KROG 1418): A Multicenter Case-Controlled Study.
Haeyoung Kim, Won Park, +19 authors, Jihye Cha.
Cancer Res Treat, 2017 Jan 06; 49(4). PMID: 28052649    Free PMC article.
Postmastectomy Radiotherapy in Patients with pT1-2N1 Breast Cancer Treated with Taxane-Based Chemotherapy: A Retrospective Multicenter Analysis (KROG 1418).
Yeon-Joo Kim, Won Park, +22 authors, Jihye Cha.
Cancer Res Treat, 2017 Jan 06; 49(4). PMID: 28052654    Free PMC article.
Nanoparticle albumin-bound paclitaxel as neoadjuvant chemotherapy of breast cancer: a systematic review and meta-analysis.
Yu Zong, Jiayi Wu, Kunwei Shen.
Oncotarget, 2017 Jan 07; 8(10). PMID: 28061451    Free PMC article.
Systematic Review.
The correlation of age with chemotherapy-induced ovarian function failure in breast cancer patients.
Ingeborg J H Vriens, Ashley J R De Bie, +6 authors, Vivianne C G Tjan-Heijnen.
Oncotarget, 2017 Jan 12; 8(7). PMID: 28076330    Free PMC article.
H19/let-7/LIN28 reciprocal negative regulatory circuit promotes breast cancer stem cell maintenance.
Fei Peng, Ting-Ting Li, +14 authors, Quentin Liu.
Cell Death Dis, 2017 Jan 20; 8(1). PMID: 28102845    Free PMC article.
Highly Cited.
Aptamer-functionalized hybrid nanoparticle for the treatment of breast cancer.
David Powell, Sruti Chandra, +8 authors, Anup Kundu.
Eur J Pharm Biopharm, 2017 Jan 31; 114. PMID: 28131717    Free PMC article.
Non-anthracycline-containing docetaxel and cyclophosphamide regimen is associated with sustained worse outcome compared with docetaxel, anthracycline and cyclophosphamide in neoadjuvant treatment of triple negative and HER2-positive breast cancer patients: updated follow-up data from NATT study.
Xiaosong Chen, Guolin Ye, +2 authors, Kunwei Shen.
Chin J Cancer Res, 2017 Feb 09; 28(6). PMID: 28174484    Free PMC article.
Neoadjuvant therapy for treatment of breast cancer: the way forward, or simply a convenient option for patients?
Abhishek Chatterjee, John K Erban.
Gland Surg, 2017 Feb 18; 6(1). PMID: 28210563    Free PMC article.
Management of Cancer in the Older Age Person: An Approach to Complex Medical Decisions.
María Vallet-Regí, Miguel Manzano, +3 authors, Lodovico Balducci.
Oncologist, 2017 Feb 22; 22(3). PMID: 28220025    Free PMC article.
Are life-saving anticancer drugs reaching all patients? Patterns and discrepancies of trastuzumab use in the European Union and the USA.
Felipe Ades, Christelle Senterre, +3 authors, Martine Piccart.
PLoS One, 2017 Mar 16; 12(3). PMID: 28291814    Free PMC article.
Estimating the Risks of Breast Cancer Radiotherapy: Evidence From Modern Radiation Doses to the Lungs and Heart and From Previous Randomized Trials.
Carolyn Taylor, Candace Correa, +16 authors, Early Breast Cancer Trialists’ Collaborative Group.
J Clin Oncol, 2017 Mar 21; 35(15). PMID: 28319436    Free PMC article.
Highly Cited.
Survival benefit needed to undergo chemotherapy: Patient and physician preferences.
Ines Vaz-Luis, Anne O'Neill, +8 authors, Ann H Partridge.
Cancer, 2017 Mar 23; 123(15). PMID: 28323331    Free PMC article.
SAFE trial: an ongoing randomized clinical study to assess the role of cardiotoxicity prevention in breast cancer patients treated with anthracyclines with or without trastuzumab.
Icro Meattini, Giuseppe Curigliano, +16 authors, Lorenzo Livi.
Med Oncol, 2017 Apr 02; 34(5). PMID: 28364270
Risk of heart disease in relation to radiotherapy and chemotherapy with anthracyclines among 19,464 breast cancer patients in Denmark, 1977-2005.
Jens Christian Rehammar, Maj-Britt Jensen, +6 authors, Marianne Ewertz.
Radiother Oncol, 2017 Apr 04; 123(2). PMID: 28365142    Free PMC article.
Subtle hippocampal deformities in breast cancer survivors with reduced episodic memory and self-reported cognitive concerns.
Alexandra C Apple, Anthony J Ryals, +7 authors, Lei Wang.
Neuroimage Clin, 2017 Apr 06; 14. PMID: 28377882    Free PMC article.
Anthracyclines in Early Breast Cancer: The ABC Trials-USOR 06-090, NSABP B-46-I/USOR 07132, and NSABP B-49 (NRG Oncology).
Joanne L Blum, Patrick J Flynn, +19 authors, Norman Wolmark.
J Clin Oncol, 2017 Apr 12; 35(23). PMID: 28398846    Free PMC article.
Highly Cited.
Making progress in early breast cancer: Taking time or accepting risk?
Gurdeep S Mannu, David Dodwell.
Eur J Cancer, 2017 Apr 16; 78. PMID: 28411447    Free PMC article.
Limitations of Personalized Medicine and Gene Assays for Breast Cancer.
David Tiberi, Laura Masucci, +5 authors, Philip Wong.
Cureus, 2017 Apr 22; 9(3). PMID: 28428927    Free PMC article.
Improved systemic treatment for early breast cancer improves cure rates, modifies metastatic pattern and shortens post-metastatic survival: 35-year results from the Munich Cancer Registry.
Dieter Hölzel, Renate Eckel, +11 authors, Jutta Engel.
J Cancer Res Clin Oncol, 2017 Apr 22; 143(9). PMID: 28429102
Phase II study of adjuvant docetaxel and carboplatin with/without doxorubicin and cyclophosphamide in triple negative breast cancer: a randomised controlled clinical trial.
Safa Najafi, Mehrdad Payandeh, +3 authors, Fereshte Abbasvandi.
Contemp Oncol (Pozn), 2017 Apr 25; 21(1). PMID: 28435404    Free PMC article.
Relationship between IHC4 score and response to neo-adjuvant chemotherapy in estrogen receptor-positive breast cancer.
A Sheri, I E Smith, +3 authors, M Dowsett.
Breast Cancer Res Treat, 2017 Apr 28; 164(2). PMID: 28447240    Free PMC article.
Pathological features of triple-negative breast cancers that showed progressive disease during neoadjuvant chemotherapy.
Yuko Tanabe, Hitoshi Tsuda, +7 authors, Kenji Tamura.
Cancer Sci, 2017 May 06; 108(7). PMID: 28474753    Free PMC article.
Activation of Akt characterizes estrogen receptor positive human breast cancers which respond to anthracyclines.
Synnøve Yndestad, Eilin Austreid, +3 authors, Hans P Eikesdal.
Oncotarget, 2017 May 06; 8(25). PMID: 28476032    Free PMC article.
Neoadjuvant Trials in ER+ Breast Cancer: A Tool for Acceleration of Drug Development and Discovery.
Angel L Guerrero-Zotano, Carlos L Arteaga.
Cancer Discov, 2017 May 13; 7(6). PMID: 28495849    Free PMC article.
An updated PREDICT breast cancer prognostication and treatment benefit prediction model with independent validation.
Francisco J Candido Dos Reis, Gordon C Wishart, +10 authors, Paul D P Pharoah.
Breast Cancer Res, 2017 May 24; 19(1). PMID: 28532503    Free PMC article.
Highly Cited.
Clinical utility of gene-expression signatures in early stage breast cancer.
Maryann Kwa, Andreas Makris, Francisco J Esteva.
Nat Rev Clin Oncol, 2017 Jun 01; 14(10). PMID: 28561071
Highly Cited. Review.
Adjuvant endocrine therapy alone in patients with node-positive, luminal A type breast cancer.
Sungmin Park, Se Kyung Lee, +7 authors, Seok Jin Nam.
Medicine (Baltimore), 2017 Jun 01; 96(22). PMID: 28562530    Free PMC article.
Breast Cancer Disparities at Home and Abroad: A Review of the Challenges and Opportunities for System-Level Change.
Katherine E Reeder-Hayes, Benjamin O Anderson.
Clin Cancer Res, 2017 Jun 03; 23(11). PMID: 28572260    Free PMC article.
Accelerated versus standard epirubicin followed by cyclophosphamide, methotrexate, and fluorouracil or capecitabine as adjuvant therapy for breast cancer in the randomised UK TACT2 trial (CRUK/05/19): a multicentre, phase 3, open-label, randomised, controlled trial.
David Cameron, James P Morden, +22 authors, TACT2 Investigators.
Lancet Oncol, 2017 Jun 11; 18(7). PMID: 28600210    Free PMC article.
Clinical use of the Oncotype DX genomic test to guide treatment decisions for patients with invasive breast cancer.
Terri P McVeigh, Michael J Kerin.
Breast Cancer (Dove Med Press), 2017 Jun 16; 9. PMID: 28615971    Free PMC article.
Neoadjuvant Therapy for Breast Cancer: Established Concepts and Emerging Strategies.
Tessa G Steenbruggen, Mette S van Ramshorst, +3 authors, Gabe S Sonke.
Drugs, 2017 Jun 16; 77(12). PMID: 28616845
Sequential versus concurrent chemotherapy for adjuvant breast cancer: does dose intensity matter?
N LeVasseur, S K Chia.
Br J Cancer, 2017 Jun 24; 117(2). PMID: 28641309    Free PMC article.
Sequential vs concurrent epirubicin and docetaxel as adjuvant chemotherapy for high-risk, node-negative, early breast cancer: an interim analysis of a randomised phase III study from the Hellenic Oncology Research Group.
Dimitrios Mavroudis, Emmanouil Saloustros, +12 authors, Vasilios Georgoulias.
Br J Cancer, 2017 Jun 24; 117(2). PMID: 28641315    Free PMC article.
A multifactorial 'Consensus Signature' by in silico analysis to predict response to neoadjuvant anthracycline-based chemotherapy in triple-negative breast cancer.
Natalie Turner, Mattia Forcato, +3 authors, Angelo Di Leo.
NPJ Breast Cancer, 2015 Jun 02; 1. PMID: 28721363    Free PMC article.
Learning from big data: are we undertreating older women with high-risk breast cancer?
Joseph A Sparano, Hyman Muss.
NPJ Breast Cancer, 2017 Jul 20; 2. PMID: 28721380    Free PMC article.
PIM1: a promising target in patients with triple-negative breast cancer.
Wen Zhao, RuiYue Qiu, Pan Li, Jin Yang.
Med Oncol, 2017 Jul 20; 34(8). PMID: 28721678
Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention.
Manuel Picon-Ruiz, Cynthia Morata-Tarifa, +2 authors, Joyce M Slingerland.
CA Cancer J Clin, 2017 Aug 02; 67(5). PMID: 28763097    Free PMC article.
Highly Cited. Review.
De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017.
G Curigliano, H J Burstein, +52 authors, B Xu.
Ann Oncol, 2017 Aug 26; 28(8). PMID: 28838210    Free PMC article.
Highly Cited.
MammaPrint versus EndoPredict: Poor correlation in disease recurrence risk classification of hormone receptor positive breast cancer.
Andreas Bösl, Andreas Spitzmüller, +3 authors, Felix Offner.
PLoS One, 2017 Aug 30; 12(8). PMID: 28850621    Free PMC article.
The use of nanoparticulates to treat breast cancer.
Xiaomeng Tang, Welley S Loc, +6 authors, James H Adair.
Nanomedicine (Lond), 2017 Sep 05; 12(19). PMID: 28868970    Free PMC article.
Decision impact and feasibility of different ASCO-recommended biomarkers in early breast cancer: Prospective comparison of molecular marker EndoPredict and protein marker uPA/PAI-1.
Johannes Ettl, Evelyn Klein, +7 authors, Marion Kiechle.
PLoS One, 2017 Sep 07; 12(9). PMID: 28877230    Free PMC article.
Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer.
Skye Hung-Chun Cheng, Tzu-Ting Huang, +6 authors, Ben-Long Yu.
PLoS One, 2017 Sep 09; 12(9). PMID: 28886126    Free PMC article.
A case report of locally advanced triple negative breast cancer showing pathological complete response to weekly paclitaxel with bevacizumab treatment following disease progression during anthracycline-based neoadjuvant chemotherapy.
Hideo Shigematsu, Shinji Ozaki, Daisuke Yasui, Taizo Hirata.
Int J Surg Case Rep, 2017 Sep 11; 39. PMID: 28888915    Free PMC article.
Impact of histopathology, tumor-infiltrating lymphocytes, and adjuvant chemotherapy on prognosis of triple-negative breast cancer.
Roberto A Leon-Ferre, Mei-Yin Polley, +15 authors, Matthew P Goetz.
Breast Cancer Res Treat, 2017 Sep 16; 167(1). PMID: 28913760    Free PMC article.
Differential presentation and survival of de novo and recurrent metastatic breast cancer over time: 1990-2010.
Judith A Malmgren, Musa Mayer, Mary K Atwood, Henry G Kaplan.
Breast Cancer Res Treat, 2017 Oct 19; 167(2). PMID: 29039120    Free PMC article.
Crizotinib, a MET inhibitor, inhibits growth, migration, and invasion of breast cancer cells in vitro and synergizes with chemotherapeutic agents.
Nehad M Ayoub, Kamal M Al-Shami, Mohammad A Alqudah, Nizar M Mhaidat.
Onco Targets Ther, 2017 Oct 19; 10. PMID: 29042798    Free PMC article.
Use of 21-gene recurrence score assay to individualize adjuvant chemotherapy recommendations in ER+/HER2- node positive breast cancer-A National Cancer Database study.
Prema P Peethambaram, Tanya L Hoskin, +3 authors, Judy C Boughey.
NPJ Breast Cancer, 2017 Oct 27; 3. PMID: 29067357    Free PMC article.
Clinical Significance of Routine Blood Test-Associated Inflammatory Index in Breast Cancer Patients.
Hong Sun, Chang-Qing Yin, +2 authors, Chun-Hui Yuan.
Med Sci Monit, 2017 Oct 27; 23. PMID: 29069071    Free PMC article.
Cost-utility and cost-effectiveness of physical exercise during adjuvant chemotherapy.
Hanna van Waart, Johanna M van Dongen, +5 authors, Neil K Aaronson.
Eur J Health Econ, 2017 Nov 01; 19(6). PMID: 29086085
Cancer testis antigen Sperm Protein 17 as a new target for triple negative breast cancer immunotherapy.
Leonardo Mirandola, Elisa Pedretti, +13 authors, Maurizio Chiriva-Internati.
Oncotarget, 2017 Nov 02; 8(43). PMID: 29088794    Free PMC article.
Assessing the Clinical Benefit of Systemic Adjuvant Therapies for Early Breast Cancer.
Volker Möbus, Susanne Hell, Marcus Schmidt.
Geburtshilfe Frauenheilkd, 2017 Nov 03; 77(10). PMID: 29093601    Free PMC article.
Treatment of triple-negative breast cancer with Chinese herbal medicine: A prospective cohort study protocol.
Hui Meng, Nan Peng, +4 authors, Xiaomin Wang.
Medicine (Baltimore), 2017 Nov 03; 96(44). PMID: 29095272    Free PMC article.
Hypoxia-related biological markers as predictors of epirubicin-based treatment responsiveness and resistance in locally advanced breast cancer.
Manuela Milani, Sergio Venturini, +14 authors, Giandomenico Roviello.
Oncotarget, 2017 Nov 08; 8(45). PMID: 29108271    Free PMC article.
20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years.
Hongchao Pan, Richard Gray, +9 authors, EBCTCG.
N Engl J Med, 2017 Nov 09; 377(19). PMID: 29117498    Free PMC article.
Highly Cited.
Discordance between oncotype DX recurrence score and RSPC for predicting residual risk of recurrence in ER-positive breast cancer.
Andrew Dodson, David Okonji, +6 authors, Mitch Dowsett.
Breast Cancer Res Treat, 2017 Nov 13; 168(1). PMID: 29128896    Free PMC article.
Evaluation of CDK12 Protein Expression as a Potential Novel Biomarker for DNA Damage Response-Targeted Therapies in Breast Cancer.
Kalnisha Naidoo, Patty T Wai, +17 authors, Rachael Natrajan.
Molecular cancer therapeutics, 2017 Nov 15; 17(1). PMID: 29133620    Free PMC article.
A metastasis biomarker (MetaSite Breast™ Score) is associated with distant recurrence in hormone receptor-positive, HER2-negative early-stage breast cancer.
Joseph A Sparano, Robert Gray, +13 authors, Joan Jones.
NPJ Breast Cancer, 2017 Nov 16; 3. PMID: 29138761    Free PMC article.
Adding high-intensity interval training to conventional training modalities: optimizing health-related outcomes during chemotherapy for breast cancer: the OptiTrain randomized controlled trial.
Sara Mijwel, Malin Backman, +6 authors, Yvonne Wengström.
Breast Cancer Res Treat, 2017 Nov 16; 168(1). PMID: 29139007    Free PMC article.
Effect of Time to Diagnostic Testing for Breast, Cervical, and Colorectal Cancer Screening Abnormalities on Screening Efficacy: A Modeling Study.
Carolyn M Rutter, Jane J Kim, +13 authors, Anna N A Tosteson.
Cancer Epidemiol Biomarkers Prev, 2017 Nov 19; 27(2). PMID: 29150480    Free PMC article.
Can routine data be used to support cancer clinical trials? A historical baseline on which to build: retrospective linkage of data from the TACT (CRUK 01/001) breast cancer trial and the National Cancer Data Repository.
Lucy Suzanne Kilburn, Maria Aresu, +3 authors, Judith Margaret Bliss.
Trials, 2017 Nov 29; 18(1). PMID: 29179731    Free PMC article.
Comparative effectiveness of incorporating a hypothetical DCIS prognostic marker into breast cancer screening.
Amy Trentham-Dietz, Mehmet Ali Ergun, +11 authors, Brian L Sprague.
Breast Cancer Res Treat, 2017 Dec 01; 168(1). PMID: 29185118    Free PMC article.
Long-term safety and survival outcomes from the Scandinavian Breast Group 2004-1 randomized phase II trial of tailored dose-dense adjuvant chemotherapy for early breast cancer.
Alexios Matikas, Sara Margolin, +12 authors, Jonas Bergh.
Breast Cancer Res Treat, 2017 Dec 01; 168(2). PMID: 29190004    Free PMC article.
Adjuvant chemotherapeutic treatment of 1650 patients with early breast cancer in routine care in Germany: data from the prospective TMK cohort study.
Steffen Dörfel, Claus-Christoph Steffens, +6 authors, TMK-Group (Tumour Registry Breast Cancer).
Breast Cancer, 2017 Dec 06; 25(3). PMID: 29204847    Free PMC article.
Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study.
Jia Yu, Bo Qin, +27 authors, Liewei Wang.
Breast Cancer Res, 2017 Dec 08; 19(1). PMID: 29212525    Free PMC article.
Large-scale DNA organization is a prognostic marker of breast cancer survival.
Martial Guillaud, Qian Ye, +5 authors, Mira Keyes.
Med Oncol, 2017 Dec 08; 35(1). PMID: 29214466
Transcriptome-wide analysis of natural antisense transcripts shows their potential role in breast cancer.
Stephane Wenric, Sonia ElGuendi, +14 authors, Vincent Bours.
Sci Rep, 2017 Dec 14; 7(1). PMID: 29234122    Free PMC article.
Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials.
Early Breast Cancer Trialists' Collaborative Group (EBCTCG).
Lancet Oncol, 2017 Dec 16; 19(1). PMID: 29242041    Free PMC article.
Highly Cited. Review.
Nuclear expression of XBP1s is correlated with breast cancer survival: a retrospective analysis based on tissue microarray.
Mengyi Wang, Shengnan Ruan, Jie Ming, Fang Dong.
Onco Targets Ther, 2017 Dec 26; 10. PMID: 29276395    Free PMC article.
Phase II study of neoadjuvant anthracycline combined with nanoparticle albumin-bound paclitaxel for human epidermal growth factor receptor 2-negative breast cancer.
Emi Ishigami, Masahiro Sakakibara, +8 authors, Masayuki Otsuka.
Mol Clin Oncol, 2017 Dec 30; 7(6). PMID: 29285378    Free PMC article.
Pharmacogenetics of response to neoadjuvant paclitaxel treatment for locally advanced breast cancer.
Andric C Perez-Ortiz, Israel Ramírez, +9 authors, Francisco J Estrada-Mena.
Oncotarget, 2018 Jan 02; 8(63). PMID: 29290962    Free PMC article.
Metronomic chemotherapy for non-metastatic triple negative breast cancer: Selection is the key.
Connie Rabanal, Rossana Ruiz, Silvia Neciosup, Henry Gomez.
World J Clin Oncol, 2018 Jan 02; 8(6). PMID: 29291168    Free PMC article.
Cost Effectiveness of Gene Expression Profile Testing in Community Practice.
Young Chandler, Clyde B Schechter, +8 authors, Jeanne S Mandelblatt.
J Clin Oncol, 2018 Jan 09; 36(6). PMID: 29309250    Free PMC article.
Association of Screening and Treatment With Breast Cancer Mortality by Molecular Subtype in US Women, 2000-2012.
Sylvia K Plevritis, Diego Munoz, +20 authors, Jeanne S Mandelblatt.
JAMA, 2018 Jan 11; 319(2). PMID: 29318276    Free PMC article.
Highly Cited.
Meta-analysis of randomized clinical trials in the era of individual patient data sharing.
Takuya Kawahara, Musashi Fukuda, +2 authors, Marc Buyse.
Int J Clin Oncol, 2018 Jan 14; 23(3). PMID: 29330642    Free PMC article.
A Risk-benefit Assessment Approach to Selection of Adjuvant Chemotherapy in Elderly Patients with Early Breast Cancer: A Mini Review.
Vivek Agarwala, Neha Choudhary, Sudeep Gupta.
Indian J Med Paediatr Oncol, 2018 Jan 16; 38(4). PMID: 29333024    Free PMC article.
Engrailed 1 overexpression as a potential prognostic marker in quintuple-negative breast cancer.
Yu Jin Kim, Minjung Sung, +4 authors, Yoon-La Choi.
Cancer biology & therapy, 2018 Jan 16; 19(4). PMID: 29333926    Free PMC article.
Minimizing inequality in access to precision medicine in breast cancer by real-time population-based molecular analysis in the SCAN-B initiative.
L Rydén, N Loman, +7 authors, Å Borg.
Br J Surg, 2018 Jan 18; 105(2). PMID: 29341157    Free PMC article.
Endocrine therapy and related issues in hormone receptor-positive early breast cancer: a roundtable discussion by the breast cancer therapy expert group (BCTEG).
Jame Abraham, Humberto Caldera, +11 authors, Chuck Vogel.
Breast Cancer Res Treat, 2018 Jan 21; 169(1). PMID: 29352368    Free PMC article.
Prospective Evaluation of the Impact of the 21-Gene Recurrence Score Assay on Adjuvant Treatment Decisions for Women with Node-Positive Breast Cancer in Ontario, Canada.
Sofia Torres, Maureen Trudeau, +7 authors, Andrea Eisen.
Oncologist, 2018 Jan 27; 23(7). PMID: 29371476    Free PMC article.
Independent replication of polymorphisms predicting toxicity in breast cancer patients randomized between dose-dense and docetaxel-containing adjuvant chemotherapy.
Annelot G J van Rossum, Marleen Kok, +12 authors, Sabine C Linn.
Oncotarget, 2018 Jan 27; 8(69). PMID: 29371927    Free PMC article.
Targeting minimal residual disease: a path to cure?
Marlise R Luskin, Mark A Murakami, Scott R Manalis, David M Weinstock.
Nat Rev Cancer, 2018 Jan 30; 18(4). PMID: 29376520    Free PMC article.
Survival and time to initiation of adjuvant chemotherapy among breast cancer patients: a systematic review and meta-analysis.
Qiao-Hui Zhan, Jian-Qin Fu, +2 authors, Chuan Wang.
Oncotarget, 2018 Feb 09; 9(2). PMID: 29416807    Free PMC article.
Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations.
Rinath Jeselsohn, Johann S Bergholz, +23 authors, Myles Brown.
Cancer Cell, 2018 Feb 14; 33(2). PMID: 29438694    Free PMC article.
Highly Cited.
Efficacy of Chemotherapy for ER-Negative and ER-Positive Isolated Locoregional Recurrence of Breast Cancer: Final Analysis of the CALOR Trial.
Irene L Wapnir, Karen N Price, +20 authors, Breast International Group.
J Clin Oncol, 2018 Feb 15; 36(11). PMID: 29443653    Free PMC article.
Development and External Validation of Prediction Models for 10-Year Survival of Invasive Breast Cancer. Comparison with PREDICT and CancerMath.
Solon Karapanagiotis, Paul D P Pharoah, Christopher H Jackson, Paul J Newcombe.
Clin Cancer Res, 2018 Feb 16; 24(9). PMID: 29444929    Free PMC article.
Luminal A Breast Cancer and Molecular Assays: A Review.
Jennifer J Gao, Sandra M Swain.
Oncologist, 2018 Feb 24; 23(5). PMID: 29472313    Free PMC article.
The Difference in Prognostic Outcomes Between De Novo Stage IV and Recurrent Metastatic Patients with Hormone Receptor-positive, HER2-negative Breast Cancer.
Jun Yamamura, Shunji Kamigaki, +2 authors, Yoshifumi Komoike.
In Vivo, 2018 Feb 25; 32(2). PMID: 29475920    Free PMC article.
Recent Improvement in the Long-term Survival of Breast Cancer Patients by Age and Stage in Japan.
Akiyo Yoshimura, Hidemi Ito, +8 authors, Yuri Ito.
J Epidemiol, 2018 Feb 27; 28(10). PMID: 29479003    Free PMC article.
Evolutionary history of metastatic breast cancer reveals minimal seeding from axillary lymph nodes.
Ikram Ullah, Govindasamy-Muralidharan Karthik, +8 authors, Jonas Bergh.
J Clin Invest, 2018 Feb 27; 128(4). PMID: 29480816    Free PMC article.
Highly Cited.
[Metastatic breast cancer in the spine : Molecular predictors for choosing adequate treatment strategies].
D Adler, M Kriegsmann, +4 authors, M Akbar.
Orthopade, 2018 Mar 01; 47(7). PMID: 29487982
A call for improved transparency in financial aspects of clinical trials: a case study of the CREATE-X trial in the New England Journal of Medicine.
Akihiko Ozaki, Morihito Takita, Tetsuya Tanimoto.
Invest New Drugs, 2018 Mar 09; 36(3). PMID: 29516231
Theranostic pH-sensitive nanoparticles for highly efficient targeted delivery of doxorubicin for breast tumor treatment.
Changqie Pan, Yuqing Liu, +4 authors, Wangjun Liao.
Int J Nanomedicine, 2018 Mar 10; 13. PMID: 29520140    Free PMC article.
Common Model Inputs Used in CISNET Collaborative Breast Cancer Modeling.
Jeanne S Mandelblatt, Aimee M Near, +8 authors, Sylvia K Plevritis.
Med Decis Making, 2018 Mar 20; 38(1_suppl). PMID: 29554466    Free PMC article.
Comparing CISNET Breast Cancer Incidence and Mortality Predictions to Observed Clinical Trial Results of Mammography Screening from Ages 40 to 49.
Jeroen J van den Broek, Nicolien T van Ravesteyn, +13 authors, Harry J de Koning.
Med Decis Making, 2018 Mar 20; 38(1_suppl). PMID: 29554468    Free PMC article.
Simulating the Impact of Risk-Based Screening and Treatment on Breast Cancer Outcomes with MISCAN-Fadia.
Jeroen J van den Broek, Nicolien T van Ravesteyn, Eveline A Heijnsdijk, Harry J de Koning.
Med Decis Making, 2018 Mar 20; 38(1_suppl). PMID: 29554469    Free PMC article.
Comparing CISNET Breast Cancer Models Using the Maximum Clinical Incidence Reduction Methodology.
Jeroen J van den Broek, Nicolien T van Ravesteyn, +10 authors, Marjolein van Ballegooijen.
Med Decis Making, 2018 Mar 20; 38(1_suppl). PMID: 29554471    Free PMC article.
Most Breast Cancer Patients with T1-2 Tumors and One to Three Positive Lymph Nodes Do Not Need Postmastectomy Radiotherapy.
Shirin Muhsen, Tracy-Ann Moo, +4 authors, Mahmoud El-Tamer.
Ann Surg Oncol, 2018 Mar 23; 25(7). PMID: 29564588    Free PMC article.
Hypothesis: can the abscopal effect explain the impact of adjuvant radiotherapy on breast cancer mortality?
Ismail Jatoi, John R Benson, Ian Kunkler.
NPJ Breast Cancer, 2018 Apr 13; 4. PMID: 29644338    Free PMC article.
Update on the Treatment of Early-Stage Triple-Negative Breast Cancer.
Priyanka Sharma.
Curr Treat Options Oncol, 2018 Apr 16; 19(5). PMID: 29656345
Current Status of Neoadjuvant Endocrine Therapy in Early Stage Breast Cancer.
Tomás Reinert, Rodrigo Gonçalves, Matthew J Ellis.
Curr Treat Options Oncol, 2018 Apr 18; 19(5). PMID: 29663173
Regenerative Potential and Inflammation-Induced Secretion Profile of Human Adipose-Derived Stromal Vascular Cells Are Influenced by Donor Variability and Prior Breast Cancer Diagnosis.
Adrienne M Parsons, Deborah M Ciombor, Paul Y Liu, Eric M Darling.
Stem Cell Rev Rep, 2018 Apr 18; 14(4). PMID: 29663271    Free PMC article.
Retrospective analysis of the impact of anthracycline dose reduction and chemotherapy delays on the outcomes of early breast cancer molecular subtypes.
Sigita Liutkauskiene, Saulius Grizas, +3 authors, Elona Juozaityte.
BMC Cancer, 2018 Apr 22; 18(1). PMID: 29678165    Free PMC article.
DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine.
Jia Yu, Bo Qin, +19 authors, Liewei Wang.
J Clin Invest, 2018 May 01; 128(6). PMID: 29708513    Free PMC article.
Anthracycline Use for Early Stage Breast Cancer in the Modern Era: a Review.
Sakshi Jasra, Jesus Anampa.
Curr Treat Options Oncol, 2018 May 13; 19(6). PMID: 29752560
How shall we treat early triple-negative breast cancer (TNBC): from the current standard to upcoming immuno-molecular strategies.
Ji Hyun Park, Jin-Hee Ahn, Sung-Bae Kim.
ESMO Open, 2018 May 17; 3(Suppl 1). PMID: 29765774    Free PMC article.
Increasing preoperative body size in breast cancer patients between 2002 and 2016: implications for prognosis.
Agatha Wisse, Helga Tryggvadottir, +4 authors, Helena Jernström.
Cancer Causes Control, 2018 May 29; 29(7). PMID: 29804217    Free PMC article.
High neutrophil to lymphocyte ratio and decreased CD69+NK cells represent a phenotype of high risk in early-stage breast cancer patients.
Pablo Mandó, Manglio Rizzo, +9 authors, Estrella Mariel Levy.
Onco Targets Ther, 2018 May 31; 11. PMID: 29844687    Free PMC article.
Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer.
Joseph A Sparano, Robert J Gray, +27 authors, George W Sledge.
N Engl J Med, 2018 Jun 05; 379(2). PMID: 29860917    Free PMC article.
Highly Cited.
Clinical application and utility of genomic assays in early-stage breast cancer: key lessons learned to date.
S K L Chia.
Curr Oncol, 2018 Jun 19; 25(Suppl 1). PMID: 29910655    Free PMC article.
Overexpression of topoisomerase II alpha protein is a factor for poor prognosis in patients with luminal B breast cancer.
Hideo Shigematsu, Shinji Ozaki, +7 authors, Kiyomi Taniyama.
Oncotarget, 2018 Jun 22; 9(42). PMID: 29928479    Free PMC article.
Lymph Node Status in Breast Cancer Does Not Predict Tumor Biology.
Danielle M Bello, Christy Russell, +2 authors, Monica Morrow.
Ann Surg Oncol, 2018 Jul 04; 25(10). PMID: 29968028    Free PMC article.
Should age impact breast cancer management in young women? Fine tuning of treatment guidelines.
Matteo B Suter, Olivia Pagani.
Ther Adv Med Oncol, 2018 Jul 07; 10. PMID: 29977348    Free PMC article.
Survival benefit of pure dose-dense chemotherapy in breast cancer: a meta-analysis of randomized controlled trials.
Wenqi Zhou, Shizhe Chen, Faliang Xu, Xiaohua Zeng.
World J Surg Oncol, 2018 Jul 17; 16(1). PMID: 30007402    Free PMC article.
Early detection and treatment strategies for breast cancer in low-income and upper middle-income countries: a modelling study.
Jeanette K Birnbaum, Catherine Duggan, Benjamin O Anderson, Ruth Etzioni.
Lancet Glob Health, 2018 Jul 18; 6(8). PMID: 30012269    Free PMC article.
Treatment patterns for adjuvant docetaxel-based chemotherapy in early-stage breast cancer in China: A pooled retrospective analysis of four observational studies.
Binghe Xu, Zhimin Shao, +7 authors, Shu Wang.
Chin J Cancer Res, 2018 Jul 27; 30(3). PMID: 30046227    Free PMC article.
The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer.
Maj-Britt Jensen, Anne-Vibeke Lænkholm, +7 authors, Bent Ejlertsen.
Breast Cancer Res, 2018 Jul 29; 20(1). PMID: 30053900    Free PMC article.
Combination of anthracyclines and anti-CD47 therapy inhibit invasive breast cancer growth while preventing cardiac toxicity by regulation of autophagy.
Yismeilin R Feliz-Mosquea, Ashley A Christensen, +13 authors, David R Soto-Pantoja.
Breast Cancer Res Treat, 2018 Jul 30; 172(1). PMID: 30056566    Free PMC article.
A proteomic analysis of chemoresistance development via sequential treatment with doxorubicin reveals novel players in MCF‑7 breast cancer cells.
Ann-Katrin Sommer, Adam Hermawan, +4 authors, Andreas Roidl.
Int J Mol Med, 2018 Aug 02; 42(4). PMID: 30066829    Free PMC article.
Associations of preoperative breast magnetic resonance imaging with subsequent mastectomy and breast cancer mortality.
Shi-Yi Wang, Jessica B Long, +6 authors, Cary P Gross.
Breast Cancer Res Treat, 2018 Aug 14; 172(2). PMID: 30099634    Free PMC article.
Overview of Breast Cancer Therapy.
Tracy-Ann Moo, Rachel Sanford, Chau Dang, Monica Morrow.
PET Clin, 2018 Aug 14; 13(3). PMID: 30100074    Free PMC article.
Perceptions of vascular access for intravenous systemic therapy and risk factors for lymphedema in early-stage breast cancer-a patient survey.
N LeVasseur, C Stober, +10 authors, M Clemons.
Curr Oncol, 2018 Aug 17; 25(4). PMID: 30111976    Free PMC article.
Adjuvant Anthracyclines in Breast Cancer: What Is Their Role?
Ami N Shah, William J Gradishar.
Oncologist, 2018 Aug 19; 23(10). PMID: 30120159    Free PMC article.
PARP9 is overexpressed in human breast cancer and promotes cancer cell migration.
Xinghong Tang, Hongying Zhang, +3 authors, Jing Jing.
Oncol Lett, 2018 Aug 22; 16(3). PMID: 30128030    Free PMC article.
Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer.
Nathaniel W Mabe, Douglas B Fox, +4 authors, James V Alvarez.
J Clin Invest, 2018 Aug 28; 128(10). PMID: 30148456    Free PMC article.
Clinical relevance of the 21-gene Recurrence Score® assay in treatment decisions for patients with node-positive breast cancer in the genomic era.
Eleftherios P Mamounas, Christy A Russell, +2 authors, Kathy S Albain.
NPJ Breast Cancer, 2018 Aug 30; 4. PMID: 30155517    Free PMC article.
Sperm-Associated Antigen 5 Expression Is Increased in Hepatocellular Carcinoma and Indicates Poor Prognosis.
Hua Zhou, Shun-Cai Wang, +2 authors, Ji-Sheng Jing.
Med Sci Monit, 2018 Aug 30; 24. PMID: 30157168    Free PMC article.
Cardio-oncology: protecting the heart from curative breast cancer treatment.
Jenica N Upshaw.
Gland Surg, 2018 Sep 04; 7(4). PMID: 30175052    Free PMC article.
Development and Validation of Nomograms for Predicting Overall and Breast Cancer-Specific Survival in Young Women with Breast Cancer: A Population-Based Study.
Yue Gong, Peng Ji, +3 authors, Zhi-Ming Shao.
Transl Oncol, 2018 Sep 07; 11(6). PMID: 30189361    Free PMC article.
Retrospective analysis of concurrent docetaxel and epirubicin neoadjuvant versus adjuvant chemotherapy: Which leads to better outcomes for different subtype breast cancer patients?
Houpu Yang, Lixin Zhou, +11 authors, Yuan Peng.
Medicine (Baltimore), 2018 Oct 07; 97(40). PMID: 30290661    Free PMC article.
Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway.
Yulin Peng, Yan Wang, +10 authors, Chuanzhu Lv.
J Exp Clin Cancer Res, 2018 Oct 14; 37(1). PMID: 30314513    Free PMC article.
Anthracycline versus nonanthracycline adjuvant therapy for early breast cancer: A systematic review and meta-analysis.
Wu Ding, Zhian Li, +3 authors, Chuanjian Tu.
Medicine (Baltimore), 2018 Oct 20; 97(42). PMID: 30335021    Free PMC article.
Systematic Review.
Olanzapine plus aprepitant, palonosetron, and dexamethasone for nausea and vomiting in patients with breast cancer receiving anthracycline: A retrospective study.
Hitoshi Kawazoe, Ryuji Uozumi, +7 authors, Yoshiaki Kamei.
Sci Rep, 2018 Nov 06; 8(1). PMID: 30389996    Free PMC article.
Is Axillary Sentinel Lymph Node Biopsy Required in Patients Who Undergo Primary Breast Surgery?
Toralf Reimer, Jutta Engel, +3 authors, Oreste David Gentilini.
Breast Care (Basel), 2018 Dec 01; 13(5). PMID: 30498416    Free PMC article.
Randomized Trial of Standard Adjuvant Chemotherapy Regimens Versus Capecitabine in Older Women With Early Breast Cancer: 10-Year Update of the CALGB 49907 Trial.
Hyman B Muss, Mei-Yin C Polley, +25 authors, Lisa Carey.
J Clin Oncol, 2019 Jul 25; 37(26). PMID: 31339827    Free PMC article.
Optimal treatment of breast cancer in women older than 75 years: a Korea Breast Cancer Registry analysis.
Ye Won Jeon, Sun Hyong You, +5 authors, Yong Seok Kim.
Breast Cancer Res Treat, 2019 Sep 08; 178(3). PMID: 31493032    Free PMC article.
Should Tumor Infiltrating Lymphocytes, Androgen Receptor, and FOXA1 Expression Predict the Clinical Outcome in Triple Negative Breast Cancer Patients?
Anita Mangia, Concetta Saponaro, +7 authors, Nicola Silvestris.
Cancers (Basel), 2019 Sep 22; 11(9). PMID: 31540486    Free PMC article.
Multigene expression signatures in early hormone receptor positive HER 2 negative breast cancer.
Tanja Ovcaricek, Iztok Takac, Erika Matos.
Radiol Oncol, 2019 Sep 26; 53(3). PMID: 31553709    Free PMC article.
Clinical Outcomes in Early Breast Cancer With a High 21-Gene Recurrence Score of 26 to 100 Assigned to Adjuvant Chemotherapy Plus Endocrine Therapy: A Secondary Analysis of the TAILORx Randomized Clinical Trial.
Joseph A Sparano, Robert J Gray, +26 authors, George W Sledge.
JAMA Oncol, 2019 Oct 01; 6(3). PMID: 31566680    Free PMC article.
External quality assessment (EQA) program for the immunohistochemical detection of ER, PR and Ki-67 in breast cancer: results of an interlaboratory reproducibility ring study in China.
Tianjie Pu, Ruohong Shui, +6 authors, China Anticancer Association Professional Committee of Tumour Pathology.
BMC Cancer, 2019 Oct 24; 19(1). PMID: 31640622    Free PMC article.
Inhibition of TFF3 Enhances Sensitivity-and Overcomes Acquired Resistance-to Doxorubicin in Estrogen Receptor-Positive Mammary Carcinoma.
Han Ming Poh, Yi Shiou Chiou, +9 authors, Peter E Lobie.
Cancers (Basel), 2019 Oct 30; 11(10). PMID: 31658702    Free PMC article.
Impact of the 21-gene recurrence score assay on chemotherapy decision making and outcomes for breast cancer patients with four or more positive lymph nodes.
Qing-Hong Zhang, Wen-Wen Zhang, +4 authors, San-Gang Wu.
Ann Transl Med, 2019 Nov 09; 7(18). PMID: 31700882    Free PMC article.
Improving chemotherapy outcome in early breast cancer.
Anurag Gupta, Rohit Joshi.
Gland Surg, 2019 Nov 20; 8(5). PMID: 31741891    Free PMC article.
Identifying breast cancer patients who require a double-check of preoperative core needle biopsy and postoperative surgical specimens to determine the molecular subtype of their tumor.
Je Hyung Park, Hyun Yul Kim, +3 authors, Hyun-June Paik.
Ann Surg Treat Res, 2019 Nov 20; 97(5). PMID: 31742206    Free PMC article.
Bromelain Enhances the Anti-tumor Effects of Cisplatin on 4T1 Breast Tumor Model In Vivo.
Nurul Elyani Mohamad, Nadiah Abu, Swee Keong Yeap, Noorjahan Banu Alitheen.
Integr Cancer Ther, 2019 Nov 23; 18. PMID: 31752555    Free PMC article.
Breast Cancer Care Quality in South Africa's Public Health System: An Evaluation Using American Society of Clinical Oncology/National Quality Forum Measures.
Daniel S O'Neil, Wenlong Carl Chen, +11 authors, Herbert Cubasch.
J Glob Oncol, 2019 Nov 27; 5. PMID: 31770052    Free PMC article.
A Nomogram To Predict The Overall Survival Of Breast Cancer Patients And Guide The Postoperative Adjuvant Chemotherapy In China.
Xin Wang, Ziwei Feng, +12 authors, Kexin Chen.
Cancer Manag Res, 2019 Dec 11; 11. PMID: 31819635    Free PMC article.
Decision of Adjuvant Systemic Treatment in HR+ HER2- Early Invasive Breast Cancer: Which Biomarkers Could Help?
Marie Alexandre, Aurélie Maran-Gonzalez, +6 authors, Séverine Guiu.
Cancer Manag Res, 2019 Dec 19; 11. PMID: 31849525    Free PMC article.
Chemotherapy in conjunction with traditional Chinese medicine for survival of patients with early female breast cancer: protocol for a non-randomized, single center prospective cohort study.
Chien-Ting Liu, Yen-Hao Chen, +2 authors, Ming-Yen Tsai.
Trials, 2019 Dec 19; 20(1). PMID: 31847861    Free PMC article.
Counseling young women with early breast cancer on fertility preservation.
M E Elena Ter Welle-Butalid, I J H Ingeborg Vriens, +5 authors, V C G Vivianne Tjan-Heijnen.
J Assist Reprod Genet, 2019 Nov 25; 36(12). PMID: 31760547    Free PMC article.
Role of patient preferences in clinical practice guidelines: a multiple methods study using guidelines from oncology as a case.
Fania R Gärtner, Johanneke E Portielje, +6 authors, Anne M Stiggelbout.
BMJ Open, 2019 Dec 08; 9(12). PMID: 31811009    Free PMC article.
Chemotherapy effectiveness in trial-underrepresented groups with early breast cancer: A retrospective cohort study.
Ewan Gray, Joachim Marti, +3 authors, SATURNE advisory group.
PLoS Med, 2020 Jan 01; 16(12). PMID: 31891574    Free PMC article.
Prognostic DNA methylation markers for hormone receptor breast cancer: a systematic review.
Tim C de Ruijter, Frank van der Heide, +3 authors, Vivianne C G Heijnen.
Breast Cancer Res, 2020 Feb 02; 22(1). PMID: 32005275    Free PMC article.
Systematic Review.
PREX1 drives spontaneous bone dissemination of ER+ breast cancer cells.
Miranda E Clements, Rachelle W Johnson.
Oncogene, 2019 Oct 23; 39(6). PMID: 31636389    Free PMC article.
Assessment of Progression-Free Survival as a Surrogate End Point of Overall Survival in First-Line Treatment of Ovarian Cancer: A Systematic Review and Meta-analysis.
Xavier Paoletti, Liz-Anne Lewsley, +19 authors, Gynecologic Cancer InterGroup (GCIG) Meta-analysis Committee.
JAMA Netw Open, 2020 Jan 11; 3(1). PMID: 31922558    Free PMC article.
Systematic Review.
Development of an Immune-Related Prognostic Signature in Breast Cancer.
Peiling Xie, Yuying Ma, +3 authors, Huimin Zhang.
Front Genet, 2020 Feb 13; 10. PMID: 32047513    Free PMC article.
Clinical and Genomic Risk to Guide the Use of Adjuvant Therapy for Breast Cancer.
Joseph A Sparano, Robert J Gray, +27 authors, George W Sledge.
N Engl J Med, 2019 Jun 04; 380(25). PMID: 31157962    Free PMC article.
Highly Cited.
Indications for prognostic gene expression profiling in early breast cancer.
Erin F Cobain, Daniel F Hayes.
Curr Treat Options Oncol, 2015 May 02; 16(5). PMID: 25929335
21-Gene Recurrence Score and Adjuvant Chemotherapy Decision for Breast Cancer Patients with Positive Lymph Nodes.
Yiwei Tong, Jiayi Wu, +6 authors, Kunwei Shen.
Sci Rep, 2019 Sep 13; 9(1). PMID: 31511599    Free PMC article.
Paclitaxel Plasma Concentration after the First Infusion Predicts Treatment-Limiting Peripheral Neuropathy.
Daniel L Hertz, Kelley M Kidwell, +9 authors, N Lynn Henry.
Clin Cancer Res, 2018 Apr 29; 24(15). PMID: 29703818    Free PMC article.
Variation in treatment and survival of older patients with non-metastatic breast cancer in five European countries: a population-based cohort study from the EURECCA Breast Cancer Group.
Marloes G M Derks, Esther Bastiaannet, +18 authors, EURECCA Breast Cancer Group.
Br J Cancer, 2018 Jun 08; 119(1). PMID: 29875471    Free PMC article.
The Spatiotemporal Evolution of Lymph Node Spread in Early Breast Cancer.
Peter Barry, Alexandra Vatsiou, +22 authors, Andrea Sottoriva.
Clin Cancer Res, 2018 Jun 13; 24(19). PMID: 29891724    Free PMC article.
Prognostic Value of Skeletal Muscle Depletion Measured on Computed Tomography for Overall Survival in Patients with Non-Metastatic Breast Cancer.
Jimi Huh, Bumhee Park, +6 authors, Tae Hee Kim.
J Breast Cancer, 2020 Mar 07; 23(1). PMID: 32140272    Free PMC article.
The Prosigna 50-gene profile and responsiveness to adjuvant anthracycline-based chemotherapy in high-risk breast cancer patients.
Maj-Britt Jensen, Anne-Vibeke Lænkholm, +9 authors, Bent Ejlertsen.
NPJ Breast Cancer, 2020 Mar 07; 6. PMID: 32140564    Free PMC article.
Association of Circulating Tumor Cells With Late Recurrence of Estrogen Receptor-Positive Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial.
Joseph Sparano, Anne O'Neill, +5 authors, Kathy D Miller.
JAMA Oncol, 2018 Jul 29; 4(12). PMID: 30054636    Free PMC article.
Highly Cited.
Impact of Guideline-Discordant Treatment on Cost and Health Care Utilization in Older Adults with Early-Stage Breast Cancer.
Courtney P Williams, Kelly M Kenzik, +8 authors, Gabrielle B Rocque.
Oncologist, 2018 Aug 19; 24(1). PMID: 30120157    Free PMC article.
Independent validation of the PREDICT breast cancer prognosis prediction tool in 45,789 patients using Scottish Cancer Registry data.
Ewan Gray, Joachim Marti, +3 authors, SATURNE Advisory Group.
Br J Cancer, 2018 Sep 18; 119(7). PMID: 30220705    Free PMC article.
Radiation Dose-Response for Risk of Myocardial Infarction in Breast Cancer Survivors.
Judy N Jacobse, Frances K Duane, +10 authors, Carolyn W Taylor.
Int J Radiat Oncol Biol Phys, 2018 Nov 06; 103(3). PMID: 30385276    Free PMC article.
Supervised versus autonomous exercise training in breast cancer patients: A multicenter randomized clinical trial.
Theresa Westphal, Gabriel Rinnerthaler, +11 authors, Richard Greil.
Cancer Med, 2018 Nov 12; 7(12). PMID: 30415507    Free PMC article.
Pathologic Complete Response (pCR) and Survival of Women with Inflammatory Breast Cancer (IBC): An Analysis Based on Biologic Subtypes and Demographic Characteristics.
Tithi Biswas, Charulata Jindal, Timothy L Fitzgerald, Jimmy T Efird.
Int J Environ Res Public Health, 2019 Jan 10; 16(1). PMID: 30621221    Free PMC article.
A multicenter survey of temporal changes in chemotherapy-induced hair loss in breast cancer patients.
Takanori Watanabe, Hiroshi Yagata, +13 authors, Yasuo Ohashi.
PLoS One, 2019 Jan 10; 14(1). PMID: 30625139    Free PMC article.
Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials.
Early Breast Cancer Trialists' Collaborative Group (EBCTCG).
Lancet, 2019 Feb 12; 393(10179). PMID: 30739743    Free PMC article.
Highly Cited.
SHON expression predicts response and relapse risk of breast cancer patients after anthracycline-based combination chemotherapy or tamoxifen treatment.
Tarek M A Abdel-Fatah, Reuben J Broom, +20 authors, Dong-Xu Liu.
Br J Cancer, 2019 Mar 01; 120(7). PMID: 30816325    Free PMC article.
Circulating tumor DNA dynamics using patient-customized assays are associated with outcome in neoadjuvantly treated breast cancer.
Timothy M Butler, Christopher T Boniface, +6 authors, Paul T Spellman.
Cold Spring Harb Mol Case Stud, 2019 Mar 06; 5(2). PMID: 30833418    Free PMC article.
Validation study of MARCKSL1 as a prognostic factor in lymph node-negative breast cancer patients.
Nina Gran Egeland, Marie Austdal, +6 authors, Kristin Jonsdottir.
PLoS One, 2019 Mar 12; 14(3). PMID: 30856208    Free PMC article.
Is surgical axillary staging necessary in women with T1 breast cancer who are treated with breast-conserving therapy?
Jin Wang, Hailin Tang, +5 authors, Jun Tang.
Cancer Commun (Lond), 2019 May 10; 39(1). PMID: 31068224    Free PMC article.
Avoiding over- and undertreatment in patients with resected node-positive breast cancer with the use of gene expression signatures: are we there yet?
A Matikas, T Foukakis, S Swain, J Bergh.
Ann Oncol, 2019 May 28; 30(7). PMID: 31131397    Free PMC article.
A Web-Based Exercise System (e-CuidateChemo) to Counter the Side Effects of Chemotherapy in Patients With Breast Cancer: Randomized Controlled Trial.
Angelica Ariza-Garcia, Mario Lozano-Lozano, +3 authors, Irene Cantarero-Villanueva.
J Med Internet Res, 2019 Jul 26; 21(7). PMID: 31342907    Free PMC article.
Depletion of the Transcriptional Coactivator Amplified in Breast Cancer 1 (AIB1) Uncovers Functionally Distinct Subpopulations in Triple-Negative Breast Cancer.
F R Saenz, V Ory, +5 authors, A T Riegel.
Neoplasia, 2019 Aug 23; 21(10). PMID: 31437536    Free PMC article.
Impact of Comorbidities and Age on Cause-Specific Mortality in Postmenopausal Patients with Breast Cancer.
Marloes G M Derks, Cornelis J H van de Velde, +7 authors, Gerrit-Jan Liefers.
Oncologist, 2019 Jan 05; 24(7). PMID: 30606886    Free PMC article.
Increased Mortality with Repeat Lumpectomy Alone After Ipsilateral Breast Tumor Recurrence.
Yonghui Su, Rong Guo, +5 authors, Jiong Wu.
Oncologist, 2019 Mar 08; 24(9). PMID: 30842240    Free PMC article.
Optimal radiotherapy for patients with internal mammary lymph node metastasis from breast cancer.
Kyungmi Yang, Haeyoung Kim, +3 authors, Won Kyung Cho.
Radiat Oncol, 2020 Mar 04; 15(1). PMID: 32122399    Free PMC article.
Influence of Competing Risks on Estimates of Recurrence Risk and Breast Cancer-specific Mortality in Analyses of the Early Breast Cancer Trialists Collaborative Group.
Ramy R Saleh, Michelle B Nadler, +3 authors, Eitan Amir.
Sci Rep, 2020 Mar 07; 10(1). PMID: 32139756    Free PMC article.
Neoadjuvant eribulin mesylate following anthracycline and taxane in triple negative breast cancer: Results from the HOPE study.
Serena Di Cosimo, Nicla La Verde, +16 authors, Filippo de Braud.
PLoS One, 2019 Aug 08; 14(8). PMID: 31390375    Free PMC article.
Myocardial dysfunction in long-term breast cancer survivors treated at ages 40-50 years.
Judy N Jacobse, Lars C Steggink, +10 authors, Flora E van Leeuwen.
Eur J Heart Fail, 2019 Nov 07; 22(2). PMID: 31696625    Free PMC article.
Adjuvant Therapy in Adrenocortical Carcinoma: Reflections and Future Directions.
Sara Bedrose, Marilyne Daher, Lina Altameemi, Mouhammed Amir Habra.
Cancers (Basel), 2020 Feb 27; 12(2). PMID: 32098326    Free PMC article.
A mouse model of chemotherapy-related cognitive impairments integrating the risk factors of aging and APOE4 genotype.
Tamar C Demby, Olga Rodriguez, +4 authors, G William Rebeck.
Behav Brain Res, 2020 Feb 07; 384. PMID: 32027870    Free PMC article.
The Utility of Oncotype DX for Adjuvant Chemotherapy Treatment Decisions in Estrogen Receptor-positive, Human Epidermal Growth Factor Receptor 2-negative, Node-negative Breast Cancer.
Hirah Rizki, Christopher Hillyar, Omar Abbassi, Sascha Miles-Dua.
Cureus, 2020 Mar 21; 12(3). PMID: 32195072    Free PMC article.
A randomized study comparing docetaxel/cyclophosphamide (TC), 5-fluorouracil/epirubicin/cyclophosphamide (FEC) followed by TC, and TC followed by FEC for patients with hormone receptor-positive HER2-negative primary breast cancer.
Hiroshi Ishiguro, Norikazu Masuda, +16 authors, Masakazu Toi.
Breast Cancer Res Treat, 2020 Mar 15; 180(3). PMID: 32170634    Free PMC article.
The impact of Oncotype DX breast cancer assay results on clinical practice: a UK experience.
Valerie E Crolley, Husam Marashi, +12 authors, Judy King.
Breast Cancer Res Treat, 2020 Mar 15; 180(3). PMID: 32170635    Free PMC article.
A Proposal to Redefine Pathologic Complete Remission as Endpoint following Neoadjuvant Chemotherapy in Early Breast Cancer.
Mircea Dediu, Christoph Zielinski.
Breast Care (Basel), 2020 Apr 02; 15(1). PMID: 32231500    Free PMC article.
Low-Fat Dietary Pattern and Cancer Mortality in the Women's Health Initiative (WHI) Randomized Controlled Trial.
Rowan T Chlebowski, Garnet L Anderson, +15 authors, Cynthia A Thomson.
JNCI Cancer Spectr, 2019 Jul 31; 2(4). PMID: 31360880    Free PMC article.
Regional nodal irradiation in pT1-2N1 breast cancer patients treated with breast-conserving surgery and whole breast irradiation.
Shin-Hyung Park, Jae-Chul Kim.
Radiat Oncol J, 2020 Apr 02; 38(1). PMID: 32229808    Free PMC article.
The Impact of Adding Taxanes to Anthracyclines on Women with Breast Cancer Receiving Adjuvant Chemotherapy.
Erina Hilaj, Alketa Ymeri, Kleva P Shpati.
Cureus, 2020 Apr 08; 12(2). PMID: 32257663    Free PMC article.
Gene Expression Profiling Tests for Early-Stage Invasive Breast Cancer: A Health Technology Assessment.
Ontario Health (Quality).
Ont Health Technol Assess Ser, 2020 Apr 15; 20(10). PMID: 32284770    Free PMC article.
Breast Cancer: A Molecularly Heterogenous Disease Needing Subtype-Specific Treatments.
Ugo Testa, Germana Castelli, Elvira Pelosi.
Med Sci (Basel), 2020 Mar 27; 8(1). PMID: 32210163    Free PMC article.
Health-related Quality of Life of Breast Cancer Survivors Attending an Exercise Intervention Study: A Five-year Follow-up.
Eija Roine, Harri Sintonen, +8 authors, Tiina Saarto.
In Vivo, 2020 Mar 01; 34(2). PMID: 32111767    Free PMC article.
Double Trouble: Contralateral Breast Cancer Risk Management in the Modern Era.
Kevin J Cheung, Nancy E Davidson.
J Natl Cancer Inst, 2019 Jan 31; 111(7). PMID: 30698728    Free PMC article.
Long-term (up to 16 months) health-related quality of life after adjuvant tailored dose-dense chemotherapy vs. standard three-weekly chemotherapy in women with high-risk early breast cancer.
Yvonne Brandberg, Hemming Johansson, +6 authors, Swedish Breast Cancer Group, the Austrian Breast, Colorectal Cancer Study Group, the German Breast Cancer Group.
Breast Cancer Res Treat, 2020 Apr 02; 181(1). PMID: 32232698    Free PMC article.
Simulation Modeling to Extend Clinical Trials of Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Early Breast Cancer.
Jinani Jayasekera, Joseph A Sparano, +5 authors, Jeanne Mandelblatt.
JNCI Cancer Spectr, 2020 Apr 28; 3(4). PMID: 32337487    Free PMC article.
Programmed death-ligand 1 gene expression is a prognostic marker in early breast cancer and provides additional prognostic value to 21-gene and 70-gene signatures in estrogen receptor-positive disease.
Ioannis Zerdes, Emmanouil G Sifakis, +6 authors, Theodoros Foukakis.
Mol Oncol, 2020 Mar 03; 14(5). PMID: 32115850    Free PMC article.
Validation of the DNA Damage Immune Response Signature in Patients With Triple-Negative Breast Cancer From the SWOG 9313c Trial.
Priyanka Sharma, William E Barlow, +19 authors, Daniel F Hayes.
J Clin Oncol, 2019 Oct 29; 37(36). PMID: 31657982    Free PMC article.
Screening for breast cancer with mammography.
Peter C Gøtzsche, Karsten Juhl Jørgensen.
Cochrane Database Syst Rev, 2013 Jun 06; (6). PMID: 23737396    Free PMC article.
Highly Cited. Systematic Review.
Correlation Between Oncotype DX, PREDICT and the Nottingham Prognostic Index: Implications for the Management of Early Breast Cancer.
Christopher Hillyar, Hirah Rizki, +4 authors, Simon Smith.
Cureus, 2020 May 10; 12(4). PMID: 32382456    Free PMC article.
Breast milk paclitaxel excretion following intravenous chemotherapy-a case report.
Christopher G C A Jackson, Tessa Morris, Noelyn Hung, Tak Hung.
Br J Cancer, 2019 Aug 01; 121(5). PMID: 31363168    Free PMC article.
Chromatin regulators mediate anthracycline sensitivity in breast cancer.
Jose A Seoane, Jacob G Kirkland, +2 authors, Christina Curtis.
Nat Med, 2019 Nov 09; 25(11). PMID: 31700186    Free PMC article.
A Network Meta-Analysis of Surgical Treatment in Patients With Early Breast Cancer.
Yu Gui, Xunzhou Liu, +5 authors, Li Chen.
J Natl Cancer Inst, 2019 Jun 13; 111(9). PMID: 31187142    Free PMC article.
Updated Survival Analysis after a Median Follow-up of 12 Years of an Anthracycline-Containing Adjuvant Prospective Multicentre, Randomised Phase III Trial on Dose-Dense Chemotherapy in Primary Node-Positive, High-Risk Breast Cancer Patients.
Mattea Reinisch, Oleg Gluz, +10 authors, Sherko Kümmel.
Breast Care (Basel), 2019 Jul 19; 14(3). PMID: 31316314    Free PMC article.
Dose-dense adjuvant chemotherapy in early breast cancer patients: 15-year results of the Phase 3 Mammella InterGruppo (MIG)-1 study.
Eva Blondeaux, Matteo Lambertini, +14 authors, Lucia Del Mastro.
Br J Cancer, 2020 Apr 02; 122(11). PMID: 32231293    Free PMC article.
Clinical Characteristics and Outcome Trends of Adjuvant Anthracycline and Taxane Regimen for Early Stage Breast Cancer.
Ashok K Vaid, Aseem Khurana, +6 authors, Kush Gupta.
World J Oncol, 2020 Jun 05; 11(3). PMID: 32494317    Free PMC article.
Risk factors of distant metastasis after surgery among different breast cancer subtypes: a hospital-based study in Indonesia.
Sumadi Lukman Anwar, Widya Surya Avanti, +5 authors, Wahyu Wulaningsih.
World J Surg Oncol, 2020 Jun 01; 18(1). PMID: 32473643    Free PMC article.
History of evidence synthesis to assess treatment effects: Personal reflections on something that is very much alive.
Mike Clarke.
J R Soc Med, 2016 Apr 10; 109(4). PMID: 27059906    Free PMC article.
EndoPredict® in early hormone receptor-positive, HER2-negative breast cancer.
K Almstedt, S Mendoza, +9 authors, M Schmidt.
Breast Cancer Res Treat, 2020 May 22; 182(1). PMID: 32436145    Free PMC article.
Long-Term Outcomes and Cost-Effectiveness of Breast Cancer Screening With Digital Breast Tomosynthesis in the United States.
Kathryn P Lowry, Amy Trentham-Dietz, +13 authors, Natasha K Stout.
J Natl Cancer Inst, 2019 Sep 11; 112(6). PMID: 31503283    Free PMC article.
Simulation of Chemotherapy Effects in Older Breast Cancer Patients With High Recurrence Scores.
Young Chandler, Jinani C Jayasekera, +3 authors, Jeanne S Mandelblatt.
J Natl Cancer Inst, 2019 Oct 16; 112(6). PMID: 31612208    Free PMC article.
Assessment of Breast Cancer Mortality Trends Associated With Mammographic Screening and Adjuvant Therapy From 1986 to 2013 in the State of Victoria, Australia.
Robert Burton, Christopher Stevenson.
JAMA Netw Open, 2020 Jun 24; 3(6). PMID: 32573707    Free PMC article.
Association between initiation of adjuvant chemotherapy beyond 30 days after surgery and overall survival among patients with triple-negative breast cancer.
Erik Heeg, Perla J Marang-van de Mheen, +5 authors, Marie-Jeanne T F D Vrancken Peeters.
Int J Cancer, 2019 Nov 14; 147(1). PMID: 31721193    Free PMC article.
Application of auto-planning in radiotherapy for breast cancer after breast-conserving surgery.
Kunzhi Chen, Jinlong Wei, +4 authors, Xin Jiang.
Sci Rep, 2020 Jul 04; 10(1). PMID: 32616839    Free PMC article.
The concordance of treatment decision guided by OncotypeDX and the PREDICT tool in real-world early-stage breast cancer.
Daniel A Goldstein, Chen Mayer, +5 authors, Hadar Goldvaser.
Cancer Med, 2020 May 07; 9(13). PMID: 32372569    Free PMC article.
Association of Sperm-Associated Antigen 5 and Treatment Response in Patients With Estrogen Receptor-Positive Breast Cancer.
Tarek M A Abdel-Fatah, Graham R Ball, +14 authors, Stephen Y T Chan.
JAMA Netw Open, 2020 Jul 08; 3(7). PMID: 32633764    Free PMC article.
Current State of the Art in the Adjuvant Systemic Treatment of Premenopausal Patients With Early Breast Cancer.
Francesca Parisi, Maria Grazia Razeti, +7 authors, Matteo Lambertini.
Clin Med Insights Oncol, 2020 Jul 11; 14. PMID: 32647477    Free PMC article.
Prediction of Successful Ovarian Protection Using Gonadotropin-Releasing Hormone Agonists During Chemotherapy in Young Estrogen Receptor-Negative Breast Cancer Patients.
Dong-Yun Lee, Ji-Yeon Kim, Jonghan Yu, Seok Won Kim.
Front Oncol, 2020 Jul 14; 10. PMID: 32656076    Free PMC article.
Bisphosphonate Choice as Adjuvant Therapy for Breast Cancer: Does it Matter?
Adam Brufsky, Aju Mathew.
J Natl Cancer Inst, 2019 Nov 07; 112(7). PMID: 31693134    Free PMC article.
Chemotherapy benefit for 'ER-positive' breast cancer and contamination of nonluminal subtypes—waiting for TAILORx and RxPONDER.
Z Sun, A Prat, +2 authors, C M Perou.
Ann Oncol, 2014 Oct 31; 26(1). PMID: 25355719    Free PMC article.
Management of hormone receptor-positive, HER2-negative early breast cancer.
Elaine M Walsh, Karen L Smith, Vered Stearns.
Semin Oncol, 2020 Jun 18; 47(4). PMID: 32546323    Free PMC article.
Adjuvant chemotherapy for node negative, high Recurrence ScoreTM breast cancer: in defense of de-escalation.
Diana Lake, Andrew D Seidman.
NPJ Breast Cancer, 2019 Aug 21; 5. PMID: 31428677    Free PMC article.
Clinicopathological characteristics, adjuvant chemotherapy decision and disease outcome in patients with breast cancer with a 21-gene recurrence score of 26-30.
Jing Yu, Jiayi Wu, +6 authors, Kunwei Shen.
Oncol Lett, 2020 Jul 30; 20(2). PMID: 32724396    Free PMC article.
AGO Recommendations for the Diagnosis and Treatment of Patients with Early Breast Cancer: Update 2019.
Nina Ditsch, Michael Untch, +42 authors, Achim Wöckel.
Breast Care (Basel), 2019 Sep 29; 14(4). PMID: 31558897    Free PMC article.
OSW-1 inhibits tumor growth and metastasis by NFATc2 on triple-negative breast cancer.
Xiaorong Ding, Yumei Li, Jun Li, Yongmei Yin.
Cancer Med, 2020 Jun 10; 9(15). PMID: 32515123    Free PMC article.
Optimal Systemic Treatment for Early Triple-Negative Breast Cancer.
Jenny Furlanetto, Sibylle Loibl.
Breast Care (Basel), 2020 Aug 11; 15(3). PMID: 32774215    Free PMC article.
New insights on PI3K/AKT pathway alterations and clinical outcomes in breast cancer.
Sherry X Yang, Eric Polley, Stanley Lipkowitz.
Cancer Treat Rev, 2016 Mar 21; 45. PMID: 26995633    Free PMC article.
Highly Cited. Review.
Decreased expression of the thyroid hormone-inactivating enzyme type 3 deiodinase is associated with lower survival rates in breast cancer.
Iuri Martin Goemann, Vicente Rodrigues Marczyk, +3 authors, Ana Luiza Maia.
Sci Rep, 2020 Aug 19; 10(1). PMID: 32807826    Free PMC article.
Twist1-Induced Epithelial Dissemination Requires Prkd1 Signaling.
Dan Georgess, Veena Padmanaban, +6 authors, Andrew J Ewald.
Cancer Res, 2019 Nov 05; 80(2). PMID: 31676574    Free PMC article.
Early stage triple negative breast cancer: Management and future directions.
Lubna N Chaudhary.
Semin Oncol, 2020 Jun 09; 47(4). PMID: 32507668    Free PMC article.
Iron(II) phthalocyanine Loaded and AS1411 Aptamer Targeting Nanoparticles: A Nanocomplex for Dual Modal Imaging and Photothermal Therapy of Breast Cancer.
Yubei He, Mengzhu Wang, +7 authors, Gengbiao Yuan.
Int J Nanomedicine, 2020 Aug 28; 15. PMID: 32848397    Free PMC article.
MiR-302b as a Combinatorial Therapeutic Approach to Improve Cisplatin Chemotherapy Efficacy in Human Triple-Negative Breast Cancer.
Alessandra Cataldo, Sandra Romero-Cordoba, +4 authors, Marilena V Iorio.
Cancers (Basel), 2020 Aug 19; 12(8). PMID: 32806777    Free PMC article.
Four cycles of docetaxel and cyclophosphamide as adjuvant chemotherapy in node negative breast cancer: A real-world study.
Atul Batra, Malek B Hannouf, Noura Alsafar, Sasha Lupichuk.
Breast, 2020 Aug 31; 54. PMID: 32861882    Free PMC article.
Quality of Life Indicators in Patients Operated on for Breast Cancer in Relation to the Type of Surgery-A Retrospective Cohort Study of Women in Serbia.
Predrag Kovačević, Snežana Miljković, +2 authors, Radmilo Janković.
Medicina (Kaunas), 2020 Aug 17; 56(8). PMID: 32796629    Free PMC article.
Predicting Expected Absolute Chemotherapy Treatment Benefit in Women With Early-Stage Breast Cancer Using EndoPredict, an Integrated 12-Gene Clinicomolecular Assay.
Hatem Soliman, Darl D Flake, +10 authors, William Gradishar.
JCO Precis Oncol, 2020 Sep 12; 3. PMID: 32914026    Free PMC article.
Bufalin attenuates triple-negative breast cancer cell stemness by inhibiting the expression of SOX2/OCT4.
Fei Chen, Li Zhu, +6 authors, Zhe Li.
Oncol Lett, 2020 Sep 17; 20(5). PMID: 32934738    Free PMC article.
Burning Questions in the Oncofertility Counseling of Young Breast Cancer Patients.
Luca Arecco, Marta Perachino, +10 authors, Matteo Lambertini.
Breast Cancer (Auckl), 2020 Sep 22; 14. PMID: 32952399    Free PMC article.
Clinical Benefits, Harms, and Cost-Effectiveness of Breast Cancer Screening for Survivors of Childhood Cancer Treated With Chest Radiation : A Comparative Modeling Study.
Jennifer M Yeh, Kathryn P Lowry, +12 authors, Natasha K Stout.
Ann Intern Med, 2020 Jul 07; 173(5). PMID: 32628531    Free PMC article.
Validity of distress thermometer for screening of anxiety and depression in family caregivers of Chinese breast cancer patients receiving postoperative chemotherapy.
Min Yang, Fei Ma, +3 authors, Binghe Xu.
Chin J Cancer Res, 2020 Sep 24; 32(4). PMID: 32963460    Free PMC article.
Potential Management of Circulating Tumor DNA as a Biomarker in Triple-Negative Breast Cancer.
Mao Shang, Chunxiao Chang, +3 authors, HuiHui Li.
J Cancer, 2018 Dec 28; 9(24). PMID: 30588246    Free PMC article.
Local and regional recurrence following mastectomy in breast cancer patients with 1-3 positive nodes: implications for postmastectomy radiotherapy volume.
Shin-Hyung Park, Jeeyeon Lee, +7 authors, Jae-Chul Kim.
Radiat Oncol J, 2019 Jan 12; 36(4). PMID: 30630267    Free PMC article.
Efficacy and tolerability of BP-C1 in metastatic breast cancer: a Phase II, randomized, double-blind, and placebo-controlled Thai multi-center study.
Kritiya Butthongkomvong, Nilubol Raunroadroong, +4 authors, Stig Larsen.
Breast Cancer (Dove Med Press), 2019 Jan 23; 11. PMID: 30666153    Free PMC article.
Efficient development and usability testing of decision support interventions for older women with breast cancer.
Kate J Lifford, Adrian Edwards, +10 authors, Kate Brain.
Patient Prefer Adherence, 2019 Jan 27; 13. PMID: 30679905    Free PMC article.
Clinical Validation of PITX2 DNA Methylation to Predict Outcome in High-Risk Breast Cancer Patients Treated with Anthracycline-Based Chemotherapy.
Manfred Schmitt, Olaf G Wilhelm, +11 authors, Marion Kiechle.
Breast Care (Basel), 2019 Feb 26; 13(6). PMID: 30800037    Free PMC article.
Adjuvant Dose-Dense Chemotherapy for Breast Cancer: Available Evidence and Recent Updates.
Fernando Kude de Almeida, Daniela Dornelles Rosa.
Breast Care (Basel), 2019 Feb 26; 13(6). PMID: 30800040    Free PMC article.
The overexpression of Rab9 promotes tumor progression regulated by XBP1 in breast cancer.
Yansong Liu, Xin Wang, +3 authors, Jun Zhang.
Onco Targets Ther, 2019 Mar 19; 12. PMID: 30881034    Free PMC article.
Clinical Significance of Lymph-Node Ratio in Determining Supraclavicular Lymph-Node Radiation Therapy in pN1 Breast Cancer Patients Who Received Breast-Conserving Treatment (KROG 14-18): A Multicenter Study.
Jaeho Kim, Won Park, +13 authors, Jihye Cha.
Cancers (Basel), 2019 May 19; 11(5). PMID: 31100839    Free PMC article.
Albumin-Bilirubin Score Predicts Tolerability to Adjuvant S-1 Monotherapy after Curative Gastrectomy.
Takashi Miwa, Mitsuro Kanda, +6 authors, Yasuhiro Kodera.
J Gastric Cancer, 2019 Jun 28; 19(2). PMID: 31245163    Free PMC article.
Doxorubicin Promotes Migration and Invasion of Breast Cancer Cells through the Upregulation of the RhoA/MLC Pathway.
Chien-Liang Liu, Ming-Jen Chen, +5 authors, Yuan-Ching Chang.
J Breast Cancer, 2019 Jul 10; 22(2). PMID: 31281722    Free PMC article.
Prognosis vs Treatment Interaction.
Jack Cuzick.
JNCI Cancer Spectr, 2018 Apr 28; 2(1). PMID: 31360838    Free PMC article.
ERCC1 Is a Predictor of Anthracycline Resistance and Taxane Sensitivity in Early Stage or Locally Advanced Breast Cancers.
Tarek M A Abdel-Fatah, Reem Ali, +7 authors, Srinivasan Madhusudan.
Cancers (Basel), 2019 Aug 14; 11(8). PMID: 31405143    Free PMC article.
De-escalation yes, but not at the expense of efficacy: in defense of better treatment.
Charles L Shapiro.
NPJ Breast Cancer, 2019 Aug 21; 5. PMID: 31428678    Free PMC article.
Triple-negative breast cancer: current perspective on the evolving therapeutic landscape.
Joe Mehanna, Fady Gh Haddad, +2 authors, Hampig Raphael Kourie.
Int J Womens Health, 2019 Aug 27; 11. PMID: 31447592    Free PMC article.
Do early HER2-overexpression breast cancer patients benefit from undergoing neoadjuvant trastuzumab and mastectomy? A meta-analysis.
Lin He, Qian Wu, +3 authors, Yuhua Song.
Cancer Manag Res, 2019 Sep 12; 11. PMID: 31507328    Free PMC article.
Cardiac mortality after radiotherapy, chemotherapy and endocrine therapy for breast cancer: Cohort study of 2 million women from 57 cancer registries in 22 countries.
Katherine E Henson, Paul McGale, +3 authors, Carolyn W Taylor.
Int J Cancer, 2020 Feb 06; 147(5). PMID: 32022260    Free PMC article.
Impact of Delayed Neoadjuvant Systemic Chemotherapy on Overall Survival Among Patients with Breast Cancer.
Debora de Melo Gagliato, Xiudong Lei, +4 authors, Mariana Chavez-MacGregor.
Oncologist, 2020 May 21;. PMID: 32431013    Free PMC article.
Does the Sequence of Anthracycline and Taxane Matter? The NeoSAMBA Trial.
José Bines, Isabele A Small, +9 authors, Martin Bonamino.
Oncologist, 2020 Jun 02;. PMID: 32476183    Free PMC article.
Time to Adjuvant Chemotherapy and Its Predictors Among Women with Breast Cancer at the University of Gondar Compressive Specialized Hospital: A Retrospective Follow-Up Study.
Adugnaw Zeleke Alem, Ejigu Gebeye Zeleke, Temesgen Yihunie Akalu.
Breast Cancer (Dove Med Press), 2020 Sep 29; 12. PMID: 32982398    Free PMC article.
Genomic Signatures in Luminal Breast Cancer.
Julian Puppe, Tabea Seifert, +3 authors, Wolfram Malter.
Breast Care (Basel), 2020 Sep 29; 15(4). PMID: 32982645    Free PMC article.
The Construction of Bone Metastasis-Specific Prognostic Model and Co-expressed Network of Alternative Splicing in Breast Cancer.
Runzhi Huang, Juanru Guo, +11 authors, Zongqiang Huang.
Front Cell Dev Biol, 2020 Sep 29; 8. PMID: 32984314    Free PMC article.
Prognostic factors in metastatic breast cancer: a prospective single-centre cohort study in a Finnish University Hospital.
Peeter Karihtala, Anniina Jääskeläinen, Nelli Roininen, Arja Jukkola.
BMJ Open, 2020 Oct 14; 10(10). PMID: 33046470    Free PMC article.
Timing of Chemotherapy and Radiotherapy Following Breast-Conserving Surgery for Early-Stage Breast Cancer: A Retrospective Analysis.
Si-Ye Chen, Yu Tang, +17 authors, Ye-Xiong Li.
Front Oncol, 2020 Oct 20; 10. PMID: 33072604    Free PMC article.
The Basement Membrane in a 3D Breast Acini Model Modulates Delivery and Anti-Proliferative Effects of Liposomal Anthracyclines.
Tabea Wiedenhoeft, Tobias Braun, +4 authors, Agnes Csiszár.
Pharmaceuticals (Basel), 2020 Sep 24; 13(9). PMID: 32961780    Free PMC article.
Gemcitabine as adjuvant chemotherapy in patients with high-risk early breast cancer-results from the randomized phase III SUCCESS-A trial.
Amelie de Gregorio, Lothar Häberle, +22 authors, Wolfgang Janni.
Breast Cancer Res, 2020 Oct 25; 22(1). PMID: 33097092    Free PMC article.
First prospective outcome data for the second-generation multigene test Endopredict in ER-positive/HER2-negative breast cancer.
Johannes Ettl, Sophie-Isabelle Anders, +5 authors, Marion Kiechle.
Arch Gynecol Obstet, 2020 Sep 10; 302(6). PMID: 32902674    Free PMC article.
Newly Synthesized Imino-Derivatives Analogues of Resveratrol Exert Inhibitory Effects in Breast Tumor Cells.
Domenico Iacopetta, Rosamaria Lappano, +10 authors, Marcello Maggiolini.
Int J Mol Sci, 2020 Oct 25; 21(20). PMID: 33096835    Free PMC article.
The Clinical Value and Interpretation of Anti-Müllerian Hormone in Women With Cancer.
Richard A Anderson, H Irene Su.
Front Endocrinol (Lausanne), 2020 Oct 30; 11. PMID: 33117288    Free PMC article.
The taxane-based chemotherapy triplet is superior to the doublet in one to nine node-positive but not node-negative triple-negative breast cancer: results from a retrospective analysis.
Sanxing Guo, Yonggang Shi, +4 authors, Xingya Li.
J Cancer, 2020 Oct 14; 11(22). PMID: 33046986    Free PMC article.
Association of Low Tumor Endothelial Cell pY397-Focal Adhesion Kinase Expression With Survival in Patients With Neoadjuvant-Treated Locally Advanced Breast Cancer.
Marina Roy-Luzarraga, Tarek Abdel-Fatah, +6 authors, Kairbaan Hodivala-Dilke.
JAMA Netw Open, 2020 Oct 28; 3(10). PMID: 33107920    Free PMC article.
Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer.
Heather A Parsons, Justin Rhoades, +39 authors, Viktor A Adalsteinsson.
Clin Cancer Res, 2020 Mar 15; 26(11). PMID: 32170028    Free PMC article.
KCNN4 induces multiple chemoresistance in breast cancer by regulating BCL2A1.
Peiyang Lin, Junjing Li, +4 authors, Chuangui Song.
Am J Cancer Res, 2020 Nov 10; 10(10). PMID: 33163271    Free PMC article.
Landmark trials in the medical oncology management of early stage breast cancer.
Whitney Hensing, Cesar A Santa-Maria, Lindsay L Peterson, Jennifer Y Sheng.
Semin Oncol, 2020 Sep 17; 47(5). PMID: 32933761    Free PMC article.
Interobserver concordance of Ki67 labeling index in breast cancer: Japan Breast Cancer Research Group Ki67 ring study.
Yoshiki Mikami, Takayuki Ueno, +6 authors, Hironobu Sasano.
Cancer Sci, 2013 Aug 03; 104(11). PMID: 23905924    Free PMC article.