Review
. 2012 May; 13(7):484-92.
doi: 10.1038/nrg3230.

Functions of DNA methylation: islands, start sites, gene bodies and beyond

Peter A Jones 1 
Affiliations
  • PMID: 22641018
  •     99 References
  •     1982 citations

Abstract

DNA methylation is frequently described as a 'silencing' epigenetic mark, and indeed this function of 5-methylcytosine was originally proposed in the 1970s. Now, thanks to improved genome-scale mapping of methylation, we can evaluate DNA methylation in different genomic contexts: transcriptional start sites with or without CpG islands, in gene bodies, at regulatory elements and at repeat sequences. The emerging picture is that the function of DNA methylation seems to vary with context, and the relationship between DNA methylation and transcription is more nuanced than we realized at first. Improving our understanding of the functions of DNA methylation is necessary for interpreting changes in this mark that are observed in diseases such as cancer.

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Marta Kulis, Simon Heath, +38 authors, José I Martín-Subero.
Nat Genet, 2012 Oct 16; 44(11). PMID: 23064414
Highly Cited.
The UCSC Cancer Genomics Browser: update 2013.
Mary Goldman, Brian Craft, +8 authors, Jingchun Zhu.
Nucleic Acids Res, 2012 Oct 31; 41(Database issue). PMID: 23109555    Free PMC article.
Highly Cited.
Mapping recently identified nucleotide variants in the genome and transcriptome.
Chun-Xiao Song, Chengqi Yi, Chuan He.
Nat Biotechnol, 2012 Nov 10; 30(11). PMID: 23138310    Free PMC article.
Highly Cited. Review.
Association of modified cytosines and the methylated DNA-binding protein MeCP2 with distinctive structural domains of lampbrush chromatin.
Garry T Morgan, Peter Jones, Michel Bellini.
Chromosome Res, 2012 Nov 15; 20(8). PMID: 23149574    Free PMC article.
Epigenetic contributions in the development of rheumatoid arthritis.
Kerstin Klein, Caroline Ospelt, Steffen Gay.
Arthritis Res Ther, 2012 Nov 21; 14(6). PMID: 23164162    Free PMC article.
Review.
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells.
Stefanie Seisenberger, Simon Andrews, +7 authors, Wolf Reik.
Mol Cell, 2012 Dec 12; 48(6). PMID: 23219530    Free PMC article.
Highly Cited.
Epigenetic mechanisms and models in the origins of asthma.
Wilfried Karmaus, Ali H Ziyab, Todd Everson, John W Holloway.
Curr Opin Allergy Clin Immunol, 2012 Dec 18; 13(1). PMID: 23242116    Free PMC article.
Review.
A molecular roadmap of reprogramming somatic cells into iPS cells.
Jose M Polo, Endre Anderssen, +17 authors, Konrad Hochedlinger.
Cell, 2012 Dec 25; 151(7). PMID: 23260147    Free PMC article.
Highly Cited.
Epigenetic aspects of lymphocyte antigen receptor gene rearrangement or 'when stochasticity completes randomness'.
Sébastien Jaeger, Bastien Fernandez, Pierre Ferrier.
Immunology, 2013 Jan 03; 139(2). PMID: 23278765    Free PMC article.
Review.
RNA-mediated toxicity in neurodegenerative disease.
Veronique V Belzil, Tania F Gendron, Leonard Petrucelli.
Mol Cell Neurosci, 2013 Jan 03; 56. PMID: 23280309    Free PMC article.
Review.
Dnmt3a protects active chromosome domains against cancer-associated hypomethylation.
Günter Raddatz, Qing Gao, +2 authors, Frank Lyko.
PLoS Genet, 2013 Jan 04; 8(12). PMID: 23284304    Free PMC article.
DNA methylation in multiple myeloma is weakly associated with gene transcription.
Sungwon Jung, Seungchan Kim, +4 authors, Bodour Salhia.
PLoS One, 2013 Jan 04; 7(12). PMID: 23285118    Free PMC article.
The role of chromatin modifiers in normal and malignant hematopoiesis.
Jill S Butler, Sharon Y R Dent.
Blood, 2013 Jan 05; 121(16). PMID: 23287864    Free PMC article.
Review.
Locus-specific DNA methylation reprogramming during early porcine embryogenesis.
Ming-Tao Zhao, Rocio M Rivera, Randall S Prather.
Biol Reprod, 2013 Jan 11; 88(2). PMID: 23303676    Free PMC article.
Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease.
Shuji Ogino, Paul Lochhead, +8 authors, Edward Giovannucci.
Mod Pathol, 2013 Jan 12; 26(4). PMID: 23307060    Free PMC article.
Highly Cited. Review.
Neuroprotective actions of perinatal choline nutrition.
Jan Krzysztof Blusztajn, Tiffany J Mellott.
Clin Chem Lab Med, 2013 Jan 15; 51(3). PMID: 23314544    Free PMC article.
Review.
On how mammalian transcription factors recognize methylated DNA.
Bethany A Buck-Koehntop, Pierre-Antoine Defossez.
Epigenetics, 2013 Jan 18; 8(2). PMID: 23324617    Free PMC article.
Review.
Epigenetic abnormalities in cancer find a "home on the range".
Hariharan Easwaran, Stephen B Baylin.
Cancer Cell, 2013 Jan 19; 23(1). PMID: 23328477    Free PMC article.
Genomic insights into cancer-associated aberrant CpG island hypermethylation.
Duncan Sproul, Richard R Meehan.
Brief Funct Genomics, 2013 Jan 24; 12(3). PMID: 23341493    Free PMC article.
Review.
Localized DNA demethylation at recombination intermediates during immunoglobulin heavy chain gene assembly.
Roza Selimyan, Rachel M Gerstein, +5 authors, Ranjan Sen.
PLoS Biol, 2013 Feb 06; 11(1). PMID: 23382652    Free PMC article.
Increased 5-methylcytosine and decreased 5-hydroxymethylcytosine levels are associated with reduced striatal A2AR levels in Huntington's disease.
Izaskun Villar-Menéndez, Marta Blanch, +6 authors, Marta Barrachina.
Neuromolecular Med, 2013 Feb 07; 15(2). PMID: 23385980
DNA methylation: roles in mammalian development.
Zachary D Smith, Alexander Meissner.
Nat Rev Genet, 2013 Feb 13; 14(3). PMID: 23400093
Highly Cited. Review.
Proteomics in epigenetics: new perspectives for cancer research.
Till Bartke, Julie Borgel, Peter A DiMaggio.
Brief Funct Genomics, 2013 Feb 13; 12(3). PMID: 23401080    Free PMC article.
Review.
An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform.
Francesco Marabita, Malin Almgren, +8 authors, David Gomez-Cabrero.
Epigenetics, 2013 Feb 21; 8(3). PMID: 23422812    Free PMC article.
Highly Cited.
Elucidating the landscape of aberrant DNA methylation in hepatocellular carcinoma.
Min-Ae Song, Maarit Tiirikainen, +3 authors, Linda L Wong.
PLoS One, 2013 Feb 26; 8(2). PMID: 23437062    Free PMC article.
The ascent of acetylation in the epigenetics of rheumatoid arthritis.
Aleksander M Grabiec, Kris A Reedquist.
Nat Rev Rheumatol, 2013 Feb 27; 9(5). PMID: 23439035
Review.
Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter.
Michele Yeo, Ken Berglund, +8 authors, Wolfgang B Liedtke.
Proc Natl Acad Sci U S A, 2013 Feb 27; 110(11). PMID: 23440186    Free PMC article.
Epigenetic methylations and their connections with metabolism.
Fulvio Chiacchiera, Andrea Piunti, Diego Pasini.
Cell Mol Life Sci, 2013 Mar 05; 70(9). PMID: 23456257
Review.
Developmentally programmed 3' CpG island methylation confers tissue- and cell-type-specific transcriptional activation.
Da-Hai Yu, Carol Ware, +6 authors, Lanlan Shen.
Mol Cell Biol, 2013 Mar 06; 33(9). PMID: 23459939    Free PMC article.
Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates.
Hannah K Long, David Sims, +8 authors, Robert J Klose.
Elife, 2013 Mar 08; 2. PMID: 23467541    Free PMC article.
Highly Cited.
Modification of enhancer chromatin: what, how, and why?
Eliezer Calo, Joanna Wysocka.
Mol Cell, 2013 Mar 12; 49(5). PMID: 23473601    Free PMC article.
Highly Cited. Review.
Epigenetic Thpok silencing limits the time window to choose CD4(+) helper-lineage fate in the thymus.
Hirokazu Tanaka, Taku Naito, +5 authors, Ichiro Taniuchi.
EMBO J, 2013 Mar 14; 32(8). PMID: 23481257    Free PMC article.
Transcriptional regulation and its misregulation in disease.
Tong Ihn Lee, Richard A Young.
Cell, 2013 Mar 19; 152(6). PMID: 23498934    Free PMC article.
Highly Cited. Review.
Comparative analysis using K-mer and K-flank patterns provides evidence for CpG island sequence evolution in mammalian genomes.
Heejoon Chae, Jinwoo Park, +2 authors, Sun Kim.
Nucleic Acids Res, 2013 Mar 23; 41(9). PMID: 23519616    Free PMC article.
DNA cytosine methylation: structural and thermodynamic characterization of the epigenetic marking mechanism.
Jin Yang, Lee Lior-Hoffmann, +2 authors, Suse Broyde.
Biochemistry, 2013 Mar 27; 52(16). PMID: 23528166    Free PMC article.
Epigenetics in Friedreich's Ataxia: Challenges and Opportunities for Therapy.
Chiranjeevi Sandi, Sahar Al-Mahdawi, Mark A Pook.
Genet Res Int, 2013 Mar 28; 2013. PMID: 23533785    Free PMC article.
Interplay between the cancer genome and epigenome.
Hui Shen, Peter W Laird.
Cell, 2013 Apr 02; 153(1). PMID: 23540689    Free PMC article.
Highly Cited. Review.
Generating new neurons to circumvent your fears: the role of IGF signaling.
R C Agis-Balboa, A Fischer.
Cell Mol Life Sci, 2013 Apr 02; 71(1). PMID: 23543251
Review.
Up-regulated expression and aberrant DNA methylation of LEP and SH3PXD2A in pre-eclampsia.
Yuqian Xiang, Yan Cheng, +8 authors, Xinzhi Zhao.
PLoS One, 2013 Apr 02; 8(3). PMID: 23544093    Free PMC article.
MicroRNA-148a can regulate runt-related transcription factor 3 gene expression via modulation of DNA methyltransferase 1 in gastric cancer.
Junbo Zuo, Jiazeng Xia, +5 authors, Hong Zhou.
Mol Cells, 2013 Apr 04; 35(4). PMID: 23549984    Free PMC article.
Developmental profiles of the murine palatal methylome.
Ratnam S Seelan, Savitri N Appana, +4 authors, Robert M Greene.
Birth Defects Res A Clin Mol Teratol, 2013 Apr 05; 97(4). PMID: 23554260    Free PMC article.
Review: Epigenetic mechanisms in ocular disease.
Shikun He, Xiaohua Li, Nymph Chan, David R Hinton.
Mol Vis, 2013 Apr 06; 19. PMID: 23559860    Free PMC article.
Review.
Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases?
Udo Oppermann.
Arthritis Res Ther, 2013 Apr 10; 15(2). PMID: 23566317    Free PMC article.
Review.
From neural development to cognition: unexpected roles for chromatin.
Jehnna L Ronan, Wei Wu, Gerald R Crabtree.
Nat Rev Genet, 2013 Apr 10; 14(5). PMID: 23568486    Free PMC article.
Highly Cited. Review.
Linking DNA methylation to the onset of human tubal ectopic pregnancy.
Lei Wang, Yi Feng, +4 authors, Ruijin Shao.
Am J Transl Res, 2013 Apr 11; 5(2). PMID: 23573357    Free PMC article.
Progress in understanding the pathogenesis of BPD using the baboon and sheep models.
Kurt H Albertine.
Semin Perinatol, 2013 Apr 16; 37(2). PMID: 23582959    Free PMC article.
Review.
Genome-wide distribution of histone H4 Lysine 16 acetylation sites and their relationship to gene expression.
Nobuo Horikoshi, Pankaj Kumar, +5 authors, Tej K Pandita.
Genome Integr, 2013 Apr 17; 4(1). PMID: 23587301    Free PMC article.
Extracting coordinated patterns of DNA methylation and gene expression in ovarian cancer.
Je-Gun Joung, Dokyoon Kim, Kyung Hwa Kim, Ju Han Kim.
J Am Med Inform Assoc, 2013 Apr 20; 20(4). PMID: 23599224    Free PMC article.
Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics.
Li Shen, Hao Wu, +5 authors, Yi Zhang.
Cell, 2013 Apr 23; 153(3). PMID: 23602152    Free PMC article.
Highly Cited.
DNA methylation and transcriptional noise.
Iksoo Huh, Jia Zeng, Taesung Park, Soojin V Yi.
Epigenetics Chromatin, 2013 Apr 27; 6(1). PMID: 23618007    Free PMC article.
HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas.
Efterpi Kostareli, Dana Holzinger, +18 authors, Jochen Hess.
J Clin Invest, 2013 May 03; 123(6). PMID: 23635773    Free PMC article.
Epigenetics of the antibody response.
Guideng Li, Hong Zan, Zhenming Xu, Paolo Casali.
Trends Immunol, 2013 May 07; 34(9). PMID: 23643790    Free PMC article.
Review.
Transcription factors that convert adult cell identity are differentially polycomb repressed.
Fred P Davis, Sean R Eddy.
PLoS One, 2013 May 08; 8(5). PMID: 23650565    Free PMC article.
Role of macrophage receptor with collagenous structure in innate immune tolerance.
Jian Jing, Ivana V Yang, +6 authors, David A Schwartz.
J Immunol, 2013 May 15; 190(12). PMID: 23667110    Free PMC article.
ZBTB33 binds unmethylated regions of the genome associated with actively expressed genes.
Adam Blattler, Lijing Yao, +3 authors, Peggy J Farnham.
Epigenetics Chromatin, 2013 May 23; 6(1). PMID: 23693142    Free PMC article.
ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection.
Hannah K Long, Neil P Blackledge, Robert J Klose.
Biochem Soc Trans, 2013 May 24; 41(3). PMID: 23697932    Free PMC article.
Highly Cited. Review.
The chromatin landscape of Kaposi's sarcoma-associated herpesvirus.
Zsolt Toth, Kevin Brulois, Jae U Jung.
Viruses, 2013 May 24; 5(5). PMID: 23698402    Free PMC article.
Review.
Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma.
Martin F Kaiser, David C Johnson, +7 authors, Gareth J Morgan.
Blood, 2013 May 24; 122(2). PMID: 23699600    Free PMC article.
SOCS-1 promoter methylation and treatment response in chronic hepatitis C patients receiving pegylated-interferon/ribavirin.
Kuo-Chih Tseng, Jian-Liang Chou, +3 authors, Michael W Y Chan.
J Clin Immunol, 2013 May 25; 33(6). PMID: 23702664
Glucose-induced metabolic memory in Schwann cells: prevention by PPAR agonists.
Esther S Kim, Fumiko Isoda, Irwin Kurland, Charles V Mobbs.
Endocrinology, 2013 May 28; 154(9). PMID: 23709088    Free PMC article.
Gene regulation by the act of long non-coding RNA transcription.
Aleksandra E Kornienko, Philipp M Guenzl, Denise P Barlow, Florian M Pauler.
BMC Biol, 2013 Jun 01; 11. PMID: 23721193    Free PMC article.
Highly Cited. Review.
Roles of small molecules in somatic cell reprogramming.
Jian-bin Su, Duan-qing Pei, Bao-ming Qin.
Acta Pharmacol Sin, 2013 Jun 04; 34(6). PMID: 23728722    Free PMC article.
Review.
Epigenetics: the fine-tuner in inflammatory bowel disease?
Eleni Stylianou.
Curr Opin Gastroenterol, 2013 Jun 08; 29(4). PMID: 23743674    Free PMC article.
Review.
Epigenetic control of skeletal muscle regeneration: Integrating genetic determinants and environmental changes.
Lorenzo Giordani, Pier Lorenzo Puri.
FEBS J, 2013 Jun 12; 280(17). PMID: 23745685    Free PMC article.
Review.
DNA methylation data analysis and its application to cancer research.
Xiaotu Ma, Yi-Wei Wang, Michael Q Zhang, Adi F Gazdar.
Epigenomics, 2013 Jun 12; 5(3). PMID: 23750645    Free PMC article.
Review.
Passive and active DNA methylation and the interplay with genetic variation in gene regulation.
Maria Gutierrez-Arcelus, Tuuli Lappalainen, +18 authors, Emmanouil T Dermitzakis.
Elife, 2013 Jun 12; 2. PMID: 23755361    Free PMC article.
Highly Cited.
Epigenetic therapy in lung cancer.
Stephen V Liu, Muller Fabbri, Barbara J Gitlitz, Ite A Laird-Offringa.
Front Oncol, 2013 Jun 12; 3. PMID: 23755372    Free PMC article.
Infection with influenza A viruses causes changes in promoter DNA methylation of inflammatory genes.
Sanjay Mukherjee, Veena C Vipat, Alok K Chakrabarti.
Influenza Other Respir Viruses, 2013 Jun 14; 7(6). PMID: 23758996    Free PMC article.
Gene expression: Disentangling DNA methylation.
Mary Muers.
Nat Rev Genet, 2013 Jun 26; 14(8). PMID: 23797851
Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods.
Michael Stevens, Jeffrey B Cheng, +8 authors, Ting Wang.
Genome Res, 2013 Jun 28; 23(9). PMID: 23804401    Free PMC article.
Highly Cited.
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm.
Bo Zhang, Yan Zhou, +30 authors, Ting Wang.
Genome Res, 2013 Jun 28; 23(9). PMID: 23804400    Free PMC article.
Highly Cited.
A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue.
Tina Rönn, Petr Volkov, +10 authors, Charlotte Ling.
PLoS Genet, 2013 Jul 05; 9(6). PMID: 23825961    Free PMC article.
Highly Cited.
DNA methylation restricts lineage-specific functions of transcription factor Gata4 during embryonic stem cell differentiation.
Masaaki Oda, Yuichi Kumaki, +5 authors, Masaki Okano.
PLoS Genet, 2013 Jul 05; 9(6). PMID: 23825962    Free PMC article.
Epigenetic biomarkers: a step forward for understanding periodontitis.
Anders M Lindroth, Yoon Jung Park.
J Periodontal Implant Sci, 2013 Jul 10; 43(3). PMID: 23837125    Free PMC article.
CpG islands under selective pressure are enriched with H3K4me3, H3K27ac and H3K36me3 histone modifications.
Most Mauluda Akhtar, Giovanni Scala, +2 authors, Antonella Monticelli.
BMC Evol Biol, 2013 Jul 11; 13. PMID: 23837650    Free PMC article.
Methylation and expression of immune and inflammatory genes in the offspring of bariatric bypass surgery patients.
Frédéric Guénard, André Tchernof, +4 authors, Marie-Claude Vohl.
J Obes, 2013 Jul 11; 2013. PMID: 23840945    Free PMC article.
Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression.
Lauren J Buro-Auriemma, Jacqueline Salit, +9 authors, Ronald G Crystal.
Hum Mol Genet, 2013 Jul 12; 22(23). PMID: 23842454    Free PMC article.
RNA interference knockdown of DNA methyl-transferase 3 affects gene alternative splicing in the honey bee.
Hongmei Li-Byarlay, Yang Li, +10 authors, Gene E Robinson.
Proc Natl Acad Sci U S A, 2013 Jul 16; 110(31). PMID: 23852726    Free PMC article.
Highly Cited.
DNA methylation and cancer diagnosis.
Yannick Delpu, Pierre Cordelier, William C Cho, Jérôme Torrisani.
Int J Mol Sci, 2013 Jul 23; 14(7). PMID: 23873296    Free PMC article.
Review.
Corruption of the intra-gene DNA methylation architecture is a hallmark of cancer.
Thomas E Bartlett, Alexey Zaikin, +3 authors, Martin Widschwendter.
PLoS One, 2013 Jul 23; 8(7). PMID: 23874574    Free PMC article.
Transient reduction of 5-methylcytosine and 5-hydroxymethylcytosine is associated with active DNA demethylation during regeneration of zebrafish fin.
Kentaro Hirose, Nobuyoshi Shimoda, Yutaka Kikuchi.
Epigenetics, 2013 Jul 25; 8(9). PMID: 23880758    Free PMC article.
Stage-specific epigenetic gene silencing during thymocyte lineage commitment.
Ichiro Taniuchi.
F1000Prime Rep, 2013 Jul 25; 5. PMID: 23882409    Free PMC article.
Epigenetic mechanisms and non-coding RNAs in osteoarthritis.
Matt J Barter, David A Young.
Curr Rheumatol Rep, 2013 Jul 28; 15(9). PMID: 23888362
Review.
Combining genomic and proteomic approaches for epigenetics research.
Yumiao Han, Benjamin A Garcia.
Epigenomics, 2013 Jul 31; 5(4). PMID: 23895656    Free PMC article.
Review.
Aberrant regulation of DNA methylation in amyotrophic lateral sclerosis: a new target of disease mechanisms.
Lee J Martin, Margaret Wong.
Neurotherapeutics, 2013 Aug 01; 10(4). PMID: 23900692    Free PMC article.
Review.
DNA methylation contributes to natural human variation.
Holger Heyn, Sebastian Moran, +8 authors, Manel Esteller.
Genome Res, 2013 Aug 03; 23(9). PMID: 23908385    Free PMC article.
Highly Cited.
Tissue-specific Leptin promoter DNA methylation is associated with maternal and infant perinatal factors.
Corina Lesseur, David A Armstrong, +3 authors, Carmen J Marsit.
Mol Cell Endocrinol, 2013 Aug 06; 381(1-2). PMID: 23911897    Free PMC article.
Potential functional roles of DNA demethylation intermediates.
Chun-Xiao Song, Chuan He.
Trends Biochem Sci, 2013 Aug 13; 38(10). PMID: 23932479    Free PMC article.
DNA methylation and childhood maltreatment: from animal models to human studies.
P-E Lutz, G Turecki.
Neuroscience, 2013 Aug 13; 264. PMID: 23933308    Free PMC article.
Review.
Genome-wide screening identifies Plasmodium chabaudi-induced modifications of DNA methylation status of Tlr1 and Tlr6 gene promoters in liver, but not spleen, of female C57BL/6 mice.
Saleh Al-Quraishy, Mohamed A Dkhil, +3 authors, Frank Wunderlich.
Parasitol Res, 2013 Aug 21; 112(11). PMID: 23949311
Origins of aberrant DNA methylation in acute myeloid leukemia.
T Schoofs, W E Berdel, C Müller-Tidow.
Leukemia, 2013 Aug 21; 28(1). PMID: 23958917
Review.
Real-time dynamics of methyl-CpG-binding domain protein 3 and its role in DNA demethylation by fluorescence correlation spectroscopy.
Yi Cui, Il-Hoon Cho, Basudev Chowdhury, Joseph Irudayaraj.
Epigenetics, 2013 Aug 27; 8(10). PMID: 23974971    Free PMC article.
Alterations of DNA methylome in human bladder cancer.
Ahmad Besaratinia, Myles Cockburn, Stella Tommasi.
Epigenetics, 2013 Aug 27; 8(10). PMID: 23975266    Free PMC article.
Review.
Epigenetic control of Epstein-Barr virus transcription - relevance to viral life cycle?
Alison J Sinclair.
Front Genet, 2013 Aug 30; 4. PMID: 23986773    Free PMC article.
A comprehensive overview of Infinium HumanMethylation450 data processing.
Sarah Dedeurwaerder, Matthieu Defrance, +3 authors, François Fuks.
Brief Bioinform, 2013 Aug 31; 15(6). PMID: 23990268    Free PMC article.
Highly Cited. Review.
A-clustering: a novel method for the detection of co-regulated methylation regions, and regions associated with exposure.
Tamar Sofer, Elizabeth D Schifano, +2 authors, Andrea A Baccarelli.
Bioinformatics, 2013 Aug 31; 29(22). PMID: 23990415    Free PMC article.
DNA methylation profiling of the fibrinogen gene landscape in human cells and during mouse and zebrafish development.
Silja Vorjohann, Jean-Luc Pitetti, +4 authors, Marguerite Neerman-Arbez.
PLoS One, 2013 Aug 31; 8(8). PMID: 23991173    Free PMC article.
Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues.
Gary C Hon, Nisha Rajagopal, +4 authors, Bing Ren.
Nat Genet, 2013 Sep 03; 45(10). PMID: 23995138    Free PMC article.
Highly Cited.
Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine.
Michael J Booth, Tobias W B Ost, +4 authors, Shankar Balasubramanian.
Nat Protoc, 2013 Sep 07; 8(10). PMID: 24008380    Free PMC article.
Highly Cited.
DNA methylation-mediated silencing of PU.1 in leukemia cells resistant to cell differentiation.
María José Fernández-Nestosa, Estefanía Monturus, +6 authors, Dora B Krimer.
Springerplus, 2013 Sep 07; 2. PMID: 24010046    Free PMC article.
Epigenetic modifications in the pathogenesis of diabetic nephropathy.
Marpadga A Reddy, Jung Tak Park, Rama Natarajan.
Semin Nephrol, 2013 Sep 10; 33(4). PMID: 24011576    Free PMC article.
Review.
Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis.
Diego M Marzese, Richard A Scolyer, +16 authors, Dave S B Hoon.
Hum Mol Genet, 2013 Sep 10; 23(1). PMID: 24014427    Free PMC article.
Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape.
Kenneth Day, Lindsay L Waite, +5 authors, Devin Absher.
Genome Biol, 2013 Sep 17; 14(9). PMID: 24034465    Free PMC article.
Highly Cited.
FastDMA: an infinium humanmethylation450 beadchip analyzer.
Dingming Wu, Jin Gu, Michael Q Zhang.
PLoS One, 2013 Sep 17; 8(9). PMID: 24040221    Free PMC article.
Proliferative status regulates HDAC11 mRNA abundance in nontransformed fibroblasts.
Tapan K Bagui, Savitha S Sharma, Le Ma, W Jack Pledger.
Cell Cycle, 2013 Sep 21; 12(21). PMID: 24047695    Free PMC article.
Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia.
Jessica Nordlund, Christofer L Bäcklin, +19 authors, Ann-Christine Syvänen.
Genome Biol, 2013 Sep 26; 14(9). PMID: 24063430    Free PMC article.
Highly Cited.
Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins.
Morgan L Maeder, James F Angstman, +10 authors, J Keith Joung.
Nat Biotechnol, 2013 Oct 11; 31(12). PMID: 24108092    Free PMC article.
Highly Cited.
Function and evolution of DNA methylation in Nasonia vitripennis.
Xu Wang, David Wheeler, +5 authors, John H Werren.
PLoS Genet, 2013 Oct 17; 9(10). PMID: 24130511    Free PMC article.
Highly Cited.
Deep bisulfite sequencing of aberrantly methylated loci in a patient with multiple methylation defects.
Jasmin Beygo, Ole Ammerpohl, +7 authors, Karin Buiting.
PLoS One, 2013 Oct 17; 8(10). PMID: 24130816    Free PMC article.
Recurrent patterns of DNA methylation in the ZNF154, CASP8, and VHL promoters across a wide spectrum of human solid epithelial tumors and cancer cell lines.
Francisco Sánchez-Vega, Valer Gotea, +5 authors, Laura Elnitski.
Epigenetics, 2013 Oct 24; 8(12). PMID: 24149212    Free PMC article.
Cross-talk between site-specific transcription factors and DNA methylation states.
Adam Blattler, Peggy J Farnham.
J Biol Chem, 2013 Oct 24; 288(48). PMID: 24151070    Free PMC article.
Highly Cited. Review.
DNA methylation is associated with an increased level of conservation at nondegenerate nucleotides in mammals.
Trees-Juen Chuang, Feng-Chi Chen.
Mol Biol Evol, 2013 Oct 26; 31(2). PMID: 24157417    Free PMC article.
Genome-wide methylation analyses of primary human leukocyte subsets identifies functionally important cell-type-specific hypomethylated regions.
Matthias Zilbauer, Tim F Rayner, +6 authors, Kenneth G C Smith.
Blood, 2013 Oct 26; 122(25). PMID: 24159175    Free PMC article.
Sex-biased methylome and transcriptome in human prefrontal cortex.
Hongqin Xu, Fan Wang, +3 authors, Huiping Zhang.
Hum Mol Genet, 2013 Oct 29; 23(5). PMID: 24163133    Free PMC article.
Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites.
Ines Florath, Katja Butterbach, +2 authors, Hermann Brenner.
Hum Mol Genet, 2013 Oct 29; 23(5). PMID: 24163245    Free PMC article.
Highly Cited.
Exercise: putting action into our epigenome.
Joshua Denham, Francine Z Marques, Brendan J O'Brien, Fadi J Charchar.
Sports Med, 2013 Oct 29; 44(2). PMID: 24163284
Review.
MicroRNA associated with dyslipidemia and coronary disease in humans.
Elena Flowers, Bradley E Aouizerat.
Physiol Genomics, 2013 Oct 31; 45(24). PMID: 24170031    Free PMC article.
Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter.
Hui Chen, Hinke G Kazemier, +3 authors, Marianne G Rots.
Nucleic Acids Res, 2013 Nov 07; 42(3). PMID: 24194590    Free PMC article.
Alterations of 5-hydroxymethylcytosine in human cancers.
Christopher J Mariani, Jozef Madzo, +2 authors, Lucy A Godley.
Cancers (Basel), 2013 Nov 10; 5(3). PMID: 24202321    Free PMC article.
Epigenomic analysis of lung adenocarcinoma reveals novel DNA methylation patterns associated with smoking.
Qiang Tan, Guan Wang, +5 authors, Shun Lu.
Onco Targets Ther, 2013 Nov 10; 6. PMID: 24204162    Free PMC article.
Long-lasting changes in DNA methylation following short-term hypoxic exposure in primary hippocampal neuronal cultures.
Iain Hartley, Fuad F Elkhoury, +5 authors, Gabriel G Haddad.
PLoS One, 2013 Nov 10; 8(10). PMID: 24205000    Free PMC article.
Epigenetic modulating agents as a new therapeutic approach in multiple myeloma.
Ken Maes, Eline Menu, +3 authors, Elke De Bruyne.
Cancers (Basel), 2013 Nov 13; 5(2). PMID: 24216985    Free PMC article.
Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma.
Hsin-Pai Li, Chen-Ching Peng, +6 authors, Yu-Sun Chang.
Oncotarget, 2013 Nov 19; 4(11). PMID: 24243817    Free PMC article.
Linear decay of retrotransposon antisense bias across genes is contingent upon tissue specificity.
Sara Linker, Dale J Hedges.
PLoS One, 2013 Nov 19; 8(11). PMID: 24244495    Free PMC article.
Differentially methylated regions in maternal and paternal uniparental disomy for chromosome 7.
Katariina Hannula-Jouppi, Mari Muurinen, +4 authors, Juha Kere.
Epigenetics, 2013 Nov 20; 9(3). PMID: 24247273    Free PMC article.
Association of the DNMT3B -579G>T polymorphism with risk of thymomas in patients with myasthenia gravis.
Fabio Coppedè, Roberta Ricciardi, +7 authors, Lucia Migliore.
PLoS One, 2013 Nov 22; 8(11). PMID: 24260492    Free PMC article.
Understanding the connection between epigenetic DNA methylation and nucleosome positioning from computer simulations.
Guillem Portella, Federica Battistini, Modesto Orozco.
PLoS Comput Biol, 2013 Nov 28; 9(11). PMID: 24278005    Free PMC article.
Identical sets of methylated and nonmethylated genes in Ciona intestinalis sperm and muscle cells.
Miho M Suzuki, Akiko Yoshinari, +7 authors, Atsuo Nakayama.
Epigenetics Chromatin, 2013 Nov 28; 6(1). PMID: 24279449    Free PMC article.
Epigenetic regulation of ASC/TMS1 expression: potential role in apoptosis and inflammasome function.
Antero Salminen, Anu Kauppinen, Mikko Hiltunen, Kai Kaarniranta.
Cell Mol Life Sci, 2013 Nov 30; 71(10). PMID: 24287895
Review.
Establishment of active chromatin structure at enhancer elements by mixed-lineage leukemia 1 to initiate estrogen-dependent gene expression.
Kwang Won Jeong, Claudia Andreu-Vieyra, +2 authors, Michael R Stallcup.
Nucleic Acids Res, 2013 Nov 30; 42(4). PMID: 24288367    Free PMC article.
Role of chromatin in water stress responses in plants.
Soon-Ki Han, Doris Wagner.
J Exp Bot, 2013 Dec 05; 65(10). PMID: 24302754    Free PMC article.
Review.
Epigenome editing.
Philipp Voigt, Danny Reinberg.
Nat Biotechnol, 2013 Dec 10; 31(12). PMID: 24316647
Corrections for mRNA extraction and sample normalization errors find increased mRNA levels may compensate for cancer haplo-insufficiency.
David A Weaver, Andrea L Nestor-Kalinoski, +4 authors, David C Allison.
Genes Chromosomes Cancer, 2013 Dec 12; 53(2). PMID: 24327546    Free PMC article.
Genetic and epigenetic control of metabolic health.
Robert Wolfgang Schwenk, Heike Vogel, Annette Schürmann.
Mol Metab, 2013 Dec 12; 2(4). PMID: 24327950    Free PMC article.
Review.
Epigenetic silencing of glutaminase 2 in human liver and colon cancers.
Jianbin Zhang, Cheng Wang, +5 authors, Dajing Xia.
BMC Cancer, 2013 Dec 18; 13. PMID: 24330717    Free PMC article.
Characterizing the strand-specific distribution of non-CpG methylation in human pluripotent cells.
Weilong Guo, Wen-Yu Chung, +2 authors, Michael Q Zhang.
Nucleic Acids Res, 2013 Dec 18; 42(5). PMID: 24343027    Free PMC article.
Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions.
Angelika Feldmann, Robert Ivanek, +3 authors, Dirk Schübeler.
PLoS Genet, 2013 Dec 25; 9(12). PMID: 24367273    Free PMC article.
Highly Cited.
Hypomethylation of the IL17RC promoter in peripheral blood leukocytes is not a hallmark of age-related macular degeneration.
Verity F Oliver, Maria Franchina, +13 authors, Shannath L Merbs.
Cell Rep, 2014 Jan 01; 5(6). PMID: 24373284    Free PMC article.
Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score.
Guido Marcucci, Pearlly Yan, +28 authors, Clara D Bloomfield.
J Clin Oncol, 2014 Jan 01; 32(6). PMID: 24378410    Free PMC article.
Highly Cited.
Characterizing DNA methylation alterations from The Cancer Genome Atlas.
Daniel J Weisenberger.
J Clin Invest, 2014 Jan 03; 124(1). PMID: 24382385    Free PMC article.
Highly Cited. Review.
Aging and epigenetic drift: a vicious cycle.
Jean-Pierre Issa.
J Clin Invest, 2014 Jan 03; 124(1). PMID: 24382386    Free PMC article.
Highly Cited. Review.
Harnessing the potential of epigenetic therapy to target solid tumors.
Nita Ahuja, Hariharan Easwaran, Stephen B Baylin.
J Clin Invest, 2014 Jan 03; 124(1). PMID: 24382390    Free PMC article.
Review.
Diagnostic and prognostic value of SHOX2 and SEPT9 DNA methylation and cytology in benign, paramalignant and malignant pleural effusions.
Dimo Dietrich, Maria Jung, +7 authors, Glen Kristiansen.
PLoS One, 2014 Jan 05; 8(12). PMID: 24386354    Free PMC article.
The RON receptor tyrosine kinase promotes metastasis by triggering MBD4-dependent DNA methylation reprogramming.
Stéphanie Cunha, Yi-Chun Lin, +5 authors, Alana L Welm.
Cell Rep, 2014 Jan 07; 6(1). PMID: 24388747    Free PMC article.
Comparison and quantitative verification of mapping algorithms for whole-genome bisulfite sequencing.
Govindarajan Kunde-Ramamoorthy, Cristian Coarfa, +7 authors, Robert A Waterland.
Nucleic Acids Res, 2014 Jan 07; 42(6). PMID: 24391148    Free PMC article.
Genome-wide methylation and gene expression changes in newborn rats following maternal protein restriction and reversal by folic acid.
Gioia Altobelli, Irina G Bogdarina, +2 authors, Simon Langley-Evans.
PLoS One, 2014 Jan 07; 8(12). PMID: 24391732    Free PMC article.
CpG distribution and methylation pattern in porcine parvovirus.
Renáta Tóth, István Mészáros, +3 authors, Zoltán Zádori.
PLoS One, 2014 Jan 07; 8(12). PMID: 24392033    Free PMC article.
Differential regulation of the ten-eleven translocation (TET) family of dioxygenases by O-linked β-N-acetylglucosamine transferase (OGT).
Qiao Zhang, Xiaoguang Liu, +4 authors, Jiemin Wong.
J Biol Chem, 2014 Jan 08; 289(9). PMID: 24394411    Free PMC article.
Highly Cited.
A DNA methylation network interaction measure, and detection of network oncomarkers.
Thomas E Bartlett, Sofia C Olhede, Alexey Zaikin.
PLoS One, 2014 Jan 09; 9(1). PMID: 24400102    Free PMC article.
H2A.B facilitates transcription elongation at methylated CpG loci.
Yibin Chen, Qiang Chen, +2 authors, Xiaochun Yu.
Genome Res, 2014 Jan 10; 24(4). PMID: 24402521    Free PMC article.
SHOOT GROWTH1 maintains Arabidopsis epigenomes by regulating IBM1.
Vincent Coustham, Daniela Vlad, +5 authors, Nicolas Bouché.
PLoS One, 2014 Jan 10; 9(1). PMID: 24404182    Free PMC article.
Epigenetic reprogramming of the type III interferon response potentiates antiviral activity and suppresses tumor growth.
Siyuan Ding, William Khoury-Hanold, Akiko Iwasaki, Michael D Robek.
PLoS Biol, 2014 Jan 11; 12(1). PMID: 24409098    Free PMC article.
Bisulfighter: accurate detection of methylated cytosines and differentially methylated regions.
Yutaka Saito, Junko Tsuji, Toutai Mituyama.
Nucleic Acids Res, 2014 Jan 16; 42(6). PMID: 24423865    Free PMC article.
Effect of estrogen receptor α binding on functional DNA methylation in breast cancer.
Matthew Ung, Xiaotu Ma, +2 authors, Chao Cheng.
Epigenetics, 2014 Jan 18; 9(4). PMID: 24434785    Free PMC article.
Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array.
Haroon Naeem, Nicholas C Wong, +5 authors, Geoff Macintyre.
BMC Genomics, 2014 Jan 23; 15. PMID: 24447442    Free PMC article.
Highly Cited.
Epigenetic reprogramming modulates malignant properties of human liver cancer.
Chiara Raggi, Valentina M Factor, +6 authors, Snorri S Thorgeirsson.
Hepatology, 2014 Jan 23; 59(6). PMID: 24449497    Free PMC article.
DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation.
D Pellacani, D Kestoras, +9 authors, N J Maitland.
Cell Death Differ, 2014 Jan 28; 21(5). PMID: 24464224    Free PMC article.
On form and function: does chromatin packing regulate the cell cycle?
David C Corney, Hilary A Coller.
Physiol Genomics, 2014 Jan 30; 46(6). PMID: 24474443    Free PMC article.
Global and gene-specific DNA methylation across multiple tissues in early infancy: implications for children's health research.
David A Armstrong, Corina Lesseur, +2 authors, Carmen J Marsit.
FASEB J, 2014 Jan 31; 28(5). PMID: 24478308    Free PMC article.
Molecular characteristics of mismatch repair genes in sporadic colorectal tumors in Czech patients.
Veronika Polakova Vymetalkova, Jana Slyskova, +8 authors, Pavel Vodicka.
BMC Med Genet, 2014 Feb 04; 15. PMID: 24484585    Free PMC article.
Targeted methylation of the epithelial cell adhesion molecule (EpCAM) promoter to silence its expression in ovarian cancer cells.
Suneetha Nunna, Richard Reinhardt, Sergey Ragozin, Albert Jeltsch.
PLoS One, 2014 Feb 04; 9(1). PMID: 24489952    Free PMC article.
Methyllysine reader plant homeodomain (PHD) finger protein 20-like 1 (PHF20L1) antagonizes DNA (cytosine-5) methyltransferase 1 (DNMT1) proteasomal degradation.
Pierre-Olivier Estève, Jolyon Terragni, +6 authors, Sriharsa Pradhan.
J Biol Chem, 2014 Feb 05; 289(12). PMID: 24492612    Free PMC article.
Differential methylation of the TRPA1 promoter in pain sensitivity.
J T Bell, A K Loomis, +20 authors, T D Spector.
Nat Commun, 2014 Feb 06; 5. PMID: 24496475    Free PMC article.
Reprogramming of the human intestinal epigenome by surgical tissue transposition.
Fides D Lay, Timothy J Triche, +7 authors, Peter A Jones.
Genome Res, 2014 Feb 12; 24(4). PMID: 24515120    Free PMC article.
BayMeth: improved DNA methylation quantification for affinity capture sequencing data using a flexible Bayesian approach.
Andrea Riebler, Mirco Menigatti, +6 authors, Mark D Robinson.
Genome Biol, 2014 Feb 13; 15(2). PMID: 24517713    Free PMC article.
Altered histone mark deposition and DNA methylation at homeobox genes in human oral squamous cell carcinoma.
Katarzyna M Marcinkiewicz, Lorraine J Gudas.
J Cell Physiol, 2014 Feb 13; 229(10). PMID: 24519855    Free PMC article.
The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts.
James R Wagner, Stephan Busche, +3 authors, Mathieu Blanchette.
Genome Biol, 2014 Feb 22; 15(2). PMID: 24555846    Free PMC article.
Highly Cited.
DNA methylation profiling in the thalamus and hippocampus of postnatal malnourished mice, including effects related to long-term potentiation.
Xiaoling Weng, Daizhan Zhou, +14 authors, Yun Liu.
BMC Neurosci, 2014 Feb 22; 15. PMID: 24555847    Free PMC article.
Transcriptional and epigenetic mechanisms underlying enhanced in vitro adipocyte differentiation by the brominated flame retardant BDE-47.
Jorke H Kamstra, Eva Hruba, +4 authors, Juliette Legler.
Environ Sci Technol, 2014 Feb 25; 48(7). PMID: 24559133    Free PMC article.
Neonatal genome-wide methylation patterns in relation to birth weight in the Norwegian Mother and Child Cohort.
Stephanie M Engel, Bonnie R Joubert, +8 authors, Stephanie J London.
Am J Epidemiol, 2014 Feb 25; 179(7). PMID: 24561991    Free PMC article.
MOABS: model based analysis of bisulfite sequencing data.
Deqiang Sun, Yuanxin Xi, +5 authors, Wei Li.
Genome Biol, 2014 Feb 26; 15(2). PMID: 24565500    Free PMC article.
Highly Cited.
Epigenetics and human obesity.
S J van Dijk, P L Molloy, +3 authors, Members of EpiSCOPE.
Int J Obes (Lond), 2014 Feb 26; 39(1). PMID: 24566855
Highly Cited. Systematic Review.
Epigenetics in the pathogenesis of rheumatoid arthritis.
Tibor T Glant, Katalin Mikecz, Tibor A Rauch.
BMC Med, 2014 Feb 27; 12. PMID: 24568138    Free PMC article.
Review.
The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide.
Erika L Moen, Amy L Stark, +2 authors, Lucy A Godley.
Mol Cancer Ther, 2014 Feb 27; 13(5). PMID: 24568970    Free PMC article.
Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue.
Jianxin Shi, Crystal N Marconett, +29 authors, Maria Teresa Landi.
Nat Commun, 2014 Feb 28; 5. PMID: 24572595    Free PMC article.
Highly Cited.
Nucleic acid oxidation in DNA damage repair and epigenetics.
Guanqun Zheng, Ye Fu, Chuan He.
Chem Rev, 2014 Mar 04; 114(8). PMID: 24580634    Free PMC article.
Review.
Long-term epigenetic effects of exposure to low doses of 56Fe in the mouse lung.
Etienne Nzabarushimana, Isabelle R Miousse, +6 authors, Igor Koturbash.
J Radiat Res, 2014 Mar 04; 55(4). PMID: 24585548    Free PMC article.
The de novo DNA methyltransferase DNMT3A in development and cancer.
Bi-Feng Chen, Wai-Yee Chan.
Epigenetics, 2014 Mar 05; 9(5). PMID: 24589714    Free PMC article.
Review.
Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain.
Lu Wen, Xianlong Li, +18 authors, Jie Qiao.
Genome Biol, 2014 Mar 07; 15(3). PMID: 24594098    Free PMC article.
Highly Cited.
LINE-1 methylation in leukocyte DNA, interaction with phosphatidylethanolamine N-methyltransferase variants and bladder cancer risk.
S M Tajuddin, A F S Amaral, +16 authors, Spanish Bladder Cancer/EPICURO Study investigators.
Br J Cancer, 2014 Mar 07; 110(8). PMID: 24595004    Free PMC article.
Human-specific epigenetic variation in the immunological Leukotriene B4 Receptor (LTB4R/BLT1) implicated in common inflammatory diseases.
Gareth A Wilson, Lee M Butcher, +6 authors, Christopher G Bell.
Genome Med, 2014 Mar 07; 6(3). PMID: 24598577    Free PMC article.
Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.
Tasnim Dayeh, Petr Volkov, +9 authors, Charlotte Ling.
PLoS Genet, 2014 Mar 08; 10(3). PMID: 24603685    Free PMC article.
Highly Cited.
TSC2 epigenetic defect in primary LAM cells. Evidence of an anchorage-independent survival.
Elena Lesma, Silvia Ancona, +6 authors, Alfredo Gorio.
J Cell Mol Med, 2014 Mar 13; 18(5). PMID: 24606538    Free PMC article.
S-adenosylmethionine levels regulate the schwann cell DNA methylome.
Marta Varela-Rey, Marta Iruarrizaga-Lejarreta, +16 authors, Ashwin Woodhoo.
Neuron, 2014 Mar 13; 81(5). PMID: 24607226    Free PMC article.
A MITE transposon insertion is associated with differential methylation at the maize flowering time QTL Vgt1.
Sara Castelletti, Roberto Tuberosa, Massimo Pindo, Silvio Salvi.
G3 (Bethesda), 2014 Mar 13; 4(5). PMID: 24607887    Free PMC article.
Methylation of migraine-related genes in different tissues of the rat.
Sieneke Labruijere, Lisette Stolk, +6 authors, Antoinette MaassenVanDenBrink.
PLoS One, 2014 Mar 13; 9(3). PMID: 24609082    Free PMC article.
Driver mutations of cancer epigenomes.
David M Roy, Logan A Walsh, Timothy A Chan.
Protein Cell, 2014 Mar 14; 5(4). PMID: 24622842    Free PMC article.
MethylExtract: High-Quality methylation maps and SNV calling from whole genome bisulfite sequencing data.
Guillermo Barturen, Antonio Rueda, José L Oliver, Michael Hackenberg.
F1000Res, 2013 Jan 01; 2. PMID: 24627790    Free PMC article.
Dnmt1-independent CG methylation contributes to nucleosome positioning in diverse eukaryotes.
Jason T Huff, Daniel Zilberman.
Cell, 2014 Mar 19; 156(6). PMID: 24630728    Free PMC article.
Interpreting the language of histone and DNA modifications.
Scott B Rothbart, Brian D Strahl.
Biochim Biophys Acta, 2014 Mar 19; 1839(8). PMID: 24631868    Free PMC article.
Highly Cited. Review.
Evolutionary conservation of the eumetazoan gene regulatory landscape.
Michaela Schwaiger, Anna Schönauer, +7 authors, Ulrich Technau.
Genome Res, 2014 Mar 20; 24(4). PMID: 24642862    Free PMC article.
Epigenetic modifications of chronic hypoxia-mediated neurodegeneration in Alzheimer's disease.
Hui Liu, Weidong Le.
Transl Neurodegener, 2014 Mar 22; 3(1). PMID: 24650677    Free PMC article.
Whole DNA methylome profiling in lung cancer cells before and after epithelial-to-mesenchymal transition.
Fatao Liu, Yi Zhou, +8 authors, Yun Liu.
Diagn Pathol, 2014 Mar 25; 9. PMID: 24655585    Free PMC article.
Genome-wide analysis of the chromatin composition of histone H2A and H3 variants in mouse embryonic stem cells.
Masashi Yukawa, Tomohiko Akiyama, +8 authors, Fugaku Aoki.
PLoS One, 2014 Mar 25; 9(3). PMID: 24658136    Free PMC article.
Gene expression regulation mediated through reversible m⁶A RNA methylation.
Ye Fu, Dan Dominissini, Gideon Rechavi, Chuan He.
Nat Rev Genet, 2014 Mar 26; 15(5). PMID: 24662220
Highly Cited. Review.
Calcium-sensing receptor silencing in colorectal cancer is associated with promoter hypermethylation and loss of acetylation on histone 3.
Irfete S Fetahu, Julia Höbaus, +5 authors, Enikő Kállay.
Int J Cancer, 2014 Apr 03; 135(9). PMID: 24691920    Free PMC article.
GCK gene-body hypomethylation is associated with the risk of coronary heart disease.
Limin Xu, Dawei Zheng, +16 authors, Shiwei Duan.
Biomed Res Int, 2014 Apr 04; 2014. PMID: 24696842    Free PMC article.
Performance evaluation of kits for bisulfite-conversion of DNA from tissues, cell lines, FFPE tissues, aspirates, lavages, effusions, plasma, serum, and urine.
Emily Eva Holmes, Maria Jung, +8 authors, Dimo Dietrich.
PLoS One, 2014 Apr 05; 9(4). PMID: 24699908    Free PMC article.
Nickel and epigenetic gene silencing.
Hong Sun, Magdy Shamy, Max Costa.
Genes (Basel), 2013 Jan 01; 4(4). PMID: 24705264    Free PMC article.
CG hypomethylation in Lsh-/- mouse embryonic fibroblasts is associated with de novo H3K4me1 formation and altered cellular plasticity.
Weishi Yu, Victorino Briones, +8 authors, Kathrin Muegge.
Proc Natl Acad Sci U S A, 2014 Apr 09; 111(16). PMID: 24711395    Free PMC article.
Human active X-specific DNA methylation events showing stability across time and tissues.
Jihoon Eric Joo, Boris Novakovic, +3 authors, Richard Saffery.
Eur J Hum Genet, 2014 Apr 10; 22(12). PMID: 24713664    Free PMC article.
Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications.
Artur Veloso, Killeen S Kirkconnell, +4 authors, Mats Ljungman.
Genome Res, 2014 Apr 10; 24(6). PMID: 24714810    Free PMC article.
Highly Cited.
The evidence for functional non-CpG methylation in mammalian cells.
Vibha Patil, Robyn L Ward, Luke B Hesson.
Epigenetics, 2014 Apr 11; 9(6). PMID: 24717538    Free PMC article.
Review.
Epigenetic and genetic mechanisms in red cell biology.
Kyle J Hewitt, Rajendran Sanalkumar, +2 authors, Emery H Bresnick.
Curr Opin Hematol, 2014 Apr 12; 21(3). PMID: 24722192    Free PMC article.
Review.
Multiscale representation of genomic signals.
Theo A Knijnenburg, Stephen A Ramsey, +6 authors, Ilya Shmulevich.
Nat Methods, 2014 Apr 15; 11(6). PMID: 24727652    Free PMC article.
An integrated epigenetic and transcriptomic analysis reveals distinct tissue-specific patterns of DNA methylation associated with atopic dermatitis.
Elke Rodríguez, Hansjörg Baurecht, +13 authors, Stephan Weidinger.
J Invest Dermatol, 2014 Apr 18; 134(7). PMID: 24739813
Epigenetic regulation by heritable RNA.
Reinhard Liebers, Minoo Rassoulzadegan, Frank Lyko.
PLoS Genet, 2014 Apr 20; 10(4). PMID: 24743450    Free PMC article.
Review.
Epigenetics of idiopathic pulmonary fibrosis.
Ivana V Yang, David A Schwartz.
Transl Res, 2014 Apr 22; 165(1). PMID: 24746870    Free PMC article.
Review.
Genome-wide DNA methylation in neonates exposed to maternal depression, anxiety, or SSRI medication during pregnancy.
Amy L Non, Alexandra M Binder, Laura D Kubzansky, Karin B Michels.
Epigenetics, 2014 Apr 23; 9(7). PMID: 24751725    Free PMC article.
Whole-mount MeFISH: a novel technique for simultaneous visualization of specific DNA methylation and protein/RNA expression.
Hirosuke Shiura, Akimitsu Okamoto, Hiroyuki Sasaki, Kuniya Abe.
PLoS One, 2014 Apr 24; 9(4). PMID: 24755742    Free PMC article.
Hemodynamic disturbed flow induces differential DNA methylation of endothelial Kruppel-Like Factor 4 promoter in vitro and in vivo.
Yi-Zhou Jiang, Juan M Jiménez, +3 authors, Peter F Davies.
Circ Res, 2014 Apr 24; 115(1). PMID: 24755985    Free PMC article.
Genome-wide analysis of histone modifications in latently HIV-1 infected T cells.
Jihwan Park, Chae Hyun Lim, +3 authors, Tae-Young Roh.
AIDS, 2014 Apr 26; 28(12). PMID: 24762674    Free PMC article.
Association of global DNA methylation and global DNA hydroxymethylation with metals and other exposures in human blood DNA samples.
Maria Tellez-Plaza, Wan-Yee Tang, +11 authors, Ana Navas-Acien.
Environ Health Perspect, 2014 Apr 29; 122(9). PMID: 24769358    Free PMC article.
The DNA methylome and transcriptome of different brain regions in schizophrenia and bipolar disorder.
Yun Xiao, Cynthia Camarillo, +14 authors, Chun Xu.
PLoS One, 2014 Apr 30; 9(4). PMID: 24776767    Free PMC article.
Epigenetic features in the oyster Crassostrea gigas suggestive of functionally relevant promoter DNA methylation in invertebrates.
Guillaume Rivière.
Front Physiol, 2014 Apr 30; 5. PMID: 24778620    Free PMC article.
A pilot genome-scale profiling of DNA methylation in sporadic pituitary macroadenomas: association with tumor invasion and histopathological subtype.
Chao Ling, Matthew Pease, +6 authors, Gabriel Zada.
PLoS One, 2014 May 02; 9(4). PMID: 24781529    Free PMC article.
Role of ZIC1 methylation in hepatocellular carcinoma and its clinical significance.
Yan-Ying Wang, Jian-Xin Jiang, +4 authors, Zeng-Guang Xu.
Tumour Biol, 2014 May 02; 35(8). PMID: 24782033
The role of epigenetics in the biology of multiple myeloma.
K Dimopoulos, P Gimsing, K Grønbæk.
Blood Cancer J, 2014 May 03; 4. PMID: 24786391    Free PMC article.
Review.
Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs.
Wilma T Steegenga, Mark V Boekschoten, +7 authors, Michael Müller.
Age (Dordr), 2014 May 03; 36(3). PMID: 24789080    Free PMC article.
Highly Cited.
Variants of a Thermus aquaticus DNA polymerase with increased selectivity for applications in allele- and methylation-specific amplification.
Matthias Drum, Ramon Kranaster, +2 authors, Andreas Marx.
PLoS One, 2014 May 08; 9(5). PMID: 24800860    Free PMC article.
Epigenetic variation in monozygotic twins: a genome-wide analysis of DNA methylation in buccal cells.
Jenny van Dongen, Erik A Ehli, +6 authors, Dorret I Boomsma.
Genes (Basel), 2014 May 08; 5(2). PMID: 24802513    Free PMC article.
Genetic and epigenetic underpinnings of eosinophilic esophagitis.
Joseph D Sherrill, Marc E Rothenberg.
Gastroenterol Clin North Am, 2014 May 13; 43(2). PMID: 24813515    Free PMC article.
DNMT3a epigenetic program regulates the HIF-2α oxygen-sensing pathway and the cellular response to hypoxia.
Gabriel Lachance, James Uniacke, +4 authors, Stephen Lee.
Proc Natl Acad Sci U S A, 2014 May 13; 111(21). PMID: 24817692    Free PMC article.
A symbiotic liaison between the genetic and epigenetic code.
Holger Heyn.
Front Genet, 2014 May 14; 5. PMID: 24822056    Free PMC article.
Review.
The dynamics of DNA methylation fidelity during mouse embryonic stem cell self-renewal and differentiation.
Lei Zhao, Ming-An Sun, +11 authors, Hehuang Xie.
Genome Res, 2014 May 20; 24(8). PMID: 24835587    Free PMC article.
TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma.
Christopher J Mariani, Aparna Vasanthakumar, +10 authors, Lucy A Godley.
Cell Rep, 2014 May 20; 7(5). PMID: 24835990    Free PMC article.
Highly Cited.
Characterization of the cartilage DNA methylome in knee and hip osteoarthritis.
Michael D Rushton, Louise N Reynard, +4 authors, John Loughlin.
Arthritis Rheumatol, 2014 May 20; 66(9). PMID: 24838673    Free PMC article.
Highly Cited.
DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver.
Timothy D Howard, Rasika A Mathias, +9 authors, Floyd H Chilton.
PLoS One, 2014 May 21; 9(5). PMID: 24842322    Free PMC article.
CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383.
Louise N Reynard, Catherine Bui, Catherine M Syddall, John Loughlin.
Hum Genet, 2014 May 28; 133(8). PMID: 24861163    Free PMC article.
Emerging topic: flow-related epigenetic regulation of endothelial phenotype through DNA methylation.
Peter F Davies, Elisabetta Manduchi, +2 authors, Yi-Zhou Jiang.
Vascul Pharmacol, 2014 May 31; 62(2). PMID: 24874278    Free PMC article.
Review.
TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells.
Chunlei Jin, Yue Lu, +4 authors, Jean-Pierre J Issa.
Nucleic Acids Res, 2014 May 31; 42(11). PMID: 24875481    Free PMC article.
Highly Cited.
Human endometrial DNA methylome is cycle-dependent and is associated with gene expression regulation.
Sahar Houshdaran, Zara Zelenko, Juan C Irwin, Linda C Giudice.
Mol Endocrinol, 2014 Jun 01; 28(7). PMID: 24877562    Free PMC article.
A Chemical Probe Targets DNA 5-Formylcytosine Sites and Inhibits TDG Excision, Polymerases Bypass, and Gene Expression.
Liang Xu, Ying-Chu Chen, +5 authors, Dong Wang.
Chem Sci, 2014 Jun 03; 5(2). PMID: 24883182    Free PMC article.
An integrated platform for bovine DNA methylome analysis suitable for small samples.
Habib A Shojaei Saadi, Alan M O'Doherty, +4 authors, Claude Robert.
BMC Genomics, 2014 Jun 11; 15. PMID: 24912542    Free PMC article.
Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer.
Phillippa C Taberlay, Aaron L Statham, +2 authors, Peter A Jones.
Genome Res, 2014 Jun 12; 24(9). PMID: 24916973    Free PMC article.
Highly Cited.
Impacts of pretranscriptional DNA methylation, transcriptional transcription factor, and posttranscriptional microRNA regulations on protein evolutionary rate.
Trees-Juen Chuang, Tai-Wei Chiang.
Genome Biol Evol, 2014 Jun 14; 6(6). PMID: 24923326    Free PMC article.
Evolutionary origin and methylation status of human intronic CpG islands that are not present in mouse.
Katrin Rademacher, Christopher Schröder, +4 authors, Bernhard Horsthemke.
Genome Biol Evol, 2014 Jun 14; 6(7). PMID: 24923327    Free PMC article.
Grasping nettles: cellular heterogeneity and other confounders in epigenome-wide association studies.
Liming Liang, William O C Cookson.
Hum Mol Genet, 2014 Jun 15; 23(R1). PMID: 24927738    Free PMC article.
Review.
Fine-scale population epigenetic structure in relation to gastrointestinal parasite load in red grouse (Lagopus lagopus scotica).
Marius A Wenzel, Stuart B Piertney.
Mol Ecol, 2014 Jun 20; 23(17). PMID: 24943398    Free PMC article.
Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets.
Elin Hall, Petr Volkov, +4 authors, Charlotte Ling.
BMC Med, 2014 Jun 24; 12. PMID: 24953961    Free PMC article.
Exposure to low-dose (56)Fe-ion radiation induces long-term epigenetic alterations in mouse bone marrow hematopoietic progenitor and stem cells.
Isabelle R Miousse, Lijian Shao, +8 authors, Igor Koturbash.
Radiat Res, 2014 Jun 25; 182(1). PMID: 24960414    Free PMC article.
Sequence-level mechanisms of human epigenome evolution.
James G D Prendergast, Emily V Chambers, Colin A M Semple.
Genome Biol Evol, 2014 Jun 27; 6(7). PMID: 24966180    Free PMC article.
DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma.
Sumadi Lukman Anwar, Ulrich Lehmann.
World J Gastroenterol, 2014 Jul 01; 20(24). PMID: 24976726    Free PMC article.
Review.
New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells.
Mira Jeong, Margaret A Goodell.
Exp Hematol, 2014 Jul 06; 42(8). PMID: 24993071    Free PMC article.
Review.
Diabetic nephropathy--emerging epigenetic mechanisms.
Mitsuo Kato, Rama Natarajan.
Nat Rev Nephrol, 2014 Jul 09; 10(9). PMID: 25003613    Free PMC article.
Highly Cited. Review.
A novel reannotation strategy for dissecting DNA methylation patterns of human long intergenic non-coding RNAs in cancers.
Hui Zhi, Shangwei Ning, +3 authors, Xia Li.
Nucleic Acids Res, 2014 Jul 12; 42(13). PMID: 25013169    Free PMC article.
Characterization of genome-methylome interactions in 22 nuclear pedigrees.
Nongluk Plongthongkum, Kristel R van Eijk, +7 authors, Kun Zhang.
PLoS One, 2014 Jul 16; 9(7). PMID: 25019935    Free PMC article.
Mutations of C-reactive protein (CRP) -286 SNP, APC and p53 in colorectal cancer: implication for a CRP-Wnt crosstalk.
Hai-Xiang Su, Hai-Hong Zhou, +10 authors, Shang-Rong Ji.
PLoS One, 2014 Jul 16; 9(7). PMID: 25025473    Free PMC article.
Genome-wide analysis of DNA methylation patterns in horse.
Ja-Rang Lee, Chang Pyo Hong, +22 authors, Heui-Soo Kim.
BMC Genomics, 2014 Jul 17; 15. PMID: 25027854    Free PMC article.
Data integration in the era of omics: current and future challenges.
David Gomez-Cabrero, Imad Abugessaisa, +7 authors, Jesper Tegnér.
BMC Syst Biol, 2014 Jul 18; 8 Suppl 2. PMID: 25032990    Free PMC article.
Highly Cited. Review.
Bis-class: a new classification tool of methylation status using bayes classifier and local methylation information.
Iksoo Huh, Xingyu Yang, Taesung Park, Soojin V Yi.
BMC Genomics, 2014 Jul 20; 15. PMID: 25037738    Free PMC article.
Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity.
Sébastien A Smallwood, Heather J Lee, +7 authors, Gavin Kelsey.
Nat Methods, 2014 Jul 22; 11(8). PMID: 25042786    Free PMC article.
Highly Cited.
Epigenetic alterations in the brain associated with HIV-1 infection and methamphetamine dependence.
Paula Desplats, Wilmar Dumaop, +6 authors, Igor Grant.
PLoS One, 2014 Jul 24; 9(7). PMID: 25054922    Free PMC article.
Genome-wide DNA methylation as an epigenetic consequence of Epstein-Barr virus infection of immortalized keratinocytes.
Christine E Birdwell, Krista J Queen, +4 authors, Rona S Scott.
J Virol, 2014 Jul 25; 88(19). PMID: 25056883    Free PMC article.
Testosterone persistently dysregulates hepatic expression of Tlr6 and Tlr8 induced by Plasmodium chabaudi malaria.
Saleh Al-Quraishy, Mohamed A Dkhil, +3 authors, Frank Wunderlich.
Parasitol Res, 2014 Jul 25; 113(10). PMID: 25056943
The potential of epigenetic therapies in neurodegenerative diseases.
Fabio Coppedè.
Front Genet, 2014 Jul 30; 5. PMID: 25071843    Free PMC article.
Review.
Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation.
Shaoke Lou, Heung-Man Lee, +14 authors, Kevin Y Yip.
Genome Biol, 2014 Jul 31; 15(7). PMID: 25074712    Free PMC article.
Highly Cited.
Integrative genomics of chronic obstructive pulmonary disease.
Brian D Hobbs, Craig P Hersh.
Biochem Biophys Res Commun, 2014 Aug 01; 452(2). PMID: 25078622    Free PMC article.
Review.
The DNA methylation landscape of human early embryos.
Hongshan Guo, Ping Zhu, +22 authors, Jie Qiao.
Nature, 2014 Aug 01; 511(7511). PMID: 25079557
Highly Cited.
Chemical methods for decoding cytosine modifications in DNA.
Michael J Booth, Eun-Ang Raiber, Shankar Balasubramanian.
Chem Rev, 2014 Aug 06; 115(6). PMID: 25094039    Free PMC article.
Review.
Epigenetics and development of food allergy (FA) in early childhood.
Xiumei Hong, Xiaobin Wang.
Curr Allergy Asthma Rep, 2014 Aug 07; 14(9). PMID: 25096861
Review.
Recent advances in developing molecular tools for targeted genome engineering of mammalian cells.
Kwang-il Lim.
BMB Rep, 2014 Aug 12; 48(1). PMID: 25104401    Free PMC article.
Review.
The interface between transcriptional and epigenetic control of effector and memory CD8⁺ T-cell differentiation.
Simon M Gray, Susan M Kaech, Matthew M Staron.
Immunol Rev, 2014 Aug 16; 261(1). PMID: 25123283    Free PMC article.
Review.
DNA demethylation and invasive cancer: implications for therapeutics.
David Cheishvili, Lisa Boureau, Moshe Szyf.
Br J Pharmacol, 2014 Aug 20; 172(11). PMID: 25134627    Free PMC article.
Review.
Multi-omic integrated networks connect DNA methylation and miRNA with skeletal muscle plasticity to chronic exercise in Type 2 diabetic obesity.
David S Rowlands, Rachel A Page, +19 authors, Eric P Hoffman.
Physiol Genomics, 2014 Aug 21; 46(20). PMID: 25138607    Free PMC article.
Role of CpG deserts in the epigenetic transgenerational inheritance of differential DNA methylation regions.
Michael K Skinner, Carlos Guerrero-Bosagna.
BMC Genomics, 2014 Aug 22; 15. PMID: 25142051    Free PMC article.
Relating gene expression evolution with CpG content changes.
Huan Yang, Dawei Li, Chao Cheng.
BMC Genomics, 2014 Aug 22; 15. PMID: 25142157    Free PMC article.
Cooperative DNA binding and protein/DNA fiber formation increases the activity of the Dnmt3a DNA methyltransferase.
Max Emperle, Arumugam Rajavelu, +2 authors, Albert Jeltsch.
J Biol Chem, 2014 Aug 26; 289(43). PMID: 25147181    Free PMC article.
High-throughput DNA analysis shows the importance of methylation in the control of immune inflammatory gene transcription in chronic periodontitis.
Ana Paula De Souza, Aline Cristiane Planello, +2 authors, Sergio Roberto Peres Line.
Clin Epigenetics, 2014 Aug 26; 6(1). PMID: 25147584    Free PMC article.
Do breast cancer cell lines provide a relevant model of the patient tumor methylome?
Leslie M Cope, Mary Jo Fackler, +5 authors, Christopher B Umbricht.
PLoS One, 2014 Aug 27; 9(8). PMID: 25157401    Free PMC article.
Advances in the profiling of DNA modifications: cytosine methylation and beyond.
Nongluk Plongthongkum, Dinh H Diep, Kun Zhang.
Nat Rev Genet, 2014 Aug 28; 15(10). PMID: 25159599
Highly Cited. Review.
Pyrene-based quantitative detection of the 5-formylcytosine loci symmetry in the CpG duplex content during TET-dependent demethylation.
Liang Xu, Ying-Chu Chen, +5 authors, Dong Wang.
Angew Chem Int Ed Engl, 2014 Aug 28; 53(42). PMID: 25159856    Free PMC article.
Modeling DNA methylation dynamics with approaches from phylogenetics.
John A Capra, Dennis Kostka.
Bioinformatics, 2014 Aug 28; 30(17). PMID: 25161227    Free PMC article.
Epigenetic modifications and potential new treatment targets in diabetic retinopathy.
Lorena Perrone, Carmela Matrone, Lalit P Singh.
J Ophthalmol, 2014 Aug 29; 2014. PMID: 25165577    Free PMC article.
Review.
Genome-wide DNA methylation patterns in LSH mutant reveals de-repression of repeat elements and redundant epigenetic silencing pathways.
Weishi Yu, Carl McIntosh, +10 authors, Kathrin Muegge.
Genome Res, 2014 Aug 30; 24(10). PMID: 25170028    Free PMC article.
Zebrafish as a model to study the role of DNA methylation in environmental toxicology.
Jorke H Kamstra, Peter Aleström, Jan M Kooter, Juliette Legler.
Environ Sci Pollut Res Int, 2014 Aug 31; 22(21). PMID: 25172464
Review.
Single molecule and single cell epigenomics.
Byung-Ryool Hyun, John L McElwee, Paul D Soloway.
Methods, 2014 Sep 11; 72. PMID: 25204781    Free PMC article.
Review.
Experience and the ever-changing brain: what the transcriptome can reveal.
Todd G Rubin, Jason D Gray, Bruce S McEwen.
Bioessays, 2014 Sep 13; 36(11). PMID: 25213333    Free PMC article.
Review.
Architectural proteins: regulators of 3D genome organization in cell fate.
Elena Gómez-Díaz, Victor G Corces.
Trends Cell Biol, 2014 Sep 15; 24(11). PMID: 25218583    Free PMC article.
Review.
Histone H2A.Z subunit exchange controls consolidation of recent and remote memory.
Iva B Zovkic, Brynna S Paulukaitis, +2 authors, J David Sweatt.
Nature, 2014 Sep 16; 515(7528). PMID: 25219850    Free PMC article.
Highly Cited.
Epigenetic mechanisms in heart failure pathogenesis.
Thomas G Di Salvo, Saptarsi M Haldar.
Circ Heart Fail, 2014 Sep 18; 7(5). PMID: 25228320    Free PMC article.
Review.
AP endonucleases process 5-methylcytosine excision intermediates during active DNA demethylation in Arabidopsis.
Jiyoon Lee, Hosung Jang, +3 authors, Jin Hoe Huh.
Nucleic Acids Res, 2014 Sep 18; 42(18). PMID: 25228464    Free PMC article.
Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels.
Nicholas E Banovich, Xun Lan, +6 authors, Yoav Gilad.
PLoS Genet, 2014 Sep 19; 10(9). PMID: 25233095    Free PMC article.
Highly Cited.
The role of epigenetics in age-related macular degeneration.
M Gemenetzi, A J Lotery.
Eye (Lond), 2014 Sep 23; 28(12). PMID: 25233816    Free PMC article.
Review.
SNP-guided identification of monoallelic DNA-methylation events from enrichment-based sequencing data.
Sandra Steyaert, Wim Van Criekinge, +6 authors, Tim De Meyer.
Nucleic Acids Res, 2014 Sep 23; 42(20). PMID: 25237057    Free PMC article.
Prognostic DNA methylation markers for prostate cancer.
Siri H Strand, Torben F Orntoft, Karina D Sorensen.
Int J Mol Sci, 2014 Sep 23; 15(9). PMID: 25238417    Free PMC article.
Review.
Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia.
Chao Chen, Chunling Zhang, +6 authors, Chunyu Liu.
Bipolar Disord, 2014 Sep 23; 16(8). PMID: 25243493    Free PMC article.
Comprehensive analysis of preeclampsia-associated DNA methylation in the placenta.
Tianjiao Chu, Kimberly Bunce, +4 authors, David Peters.
PLoS One, 2014 Sep 24; 9(9). PMID: 25247495    Free PMC article.
High-throughput engineering of a mammalian genome reveals building principles of methylation states at CG rich regions.
Arnaud R Krebs, Sophie Dessus-Babus, Lukas Burger, Dirk Schübeler.
Elife, 2014 Sep 27; 3. PMID: 25259795    Free PMC article.
Identification of a DNA methylation signature to predict disease-free survival in locally advanced rectal cancer.
Jochen Gaedcke, Andreas Leha, +12 authors, Michael Ghadimi.
Oncotarget, 2014 Sep 28; 5(18). PMID: 25261372    Free PMC article.
Gene body methylation can alter gene expression and is a therapeutic target in cancer.
Xiaojing Yang, Han Han, +3 authors, Gangning Liang.
Cancer Cell, 2014 Sep 30; 26(4). PMID: 25263941    Free PMC article.
Highly Cited.
CBFB-MYH11 hypomethylation signature and PBX3 differential methylation revealed by targeted bisulfite sequencing in patients with acute myeloid leukemia.
Hana Hájková, Markus Hsi-Yang Fritz, +11 authors, Vladimír Beneš.
J Hematol Oncol, 2014 Oct 01; 7. PMID: 25266220    Free PMC article.
Genetic and epigenetic regulation of gene expression in fetal and adult human livers.
Marc Jan Bonder, Silva Kasela, +17 authors, Lili Milani.
BMC Genomics, 2014 Oct 06; 15. PMID: 25282492    Free PMC article.
Early developmental conditioning of later health and disease: physiology or pathophysiology?
M A Hanson, P D Gluckman.
Physiol Rev, 2014 Oct 08; 94(4). PMID: 25287859    Free PMC article.
Highly Cited. Review.
Prenatal arsenic exposure and the epigenome: identifying sites of 5-methylcytosine alterations that predict functional changes in gene expression in newborn cord blood and subsequent birth outcomes.
Daniel Rojas, Julia E Rager, +6 authors, Rebecca C Fry.
Toxicol Sci, 2014 Oct 12; 143(1). PMID: 25304211    Free PMC article.
Highly Cited.
Genome-wide DNA methylation profiles and their relationships with mRNA and the microRNA transcriptome in bovine muscle tissue (Bos taurine).
Yong-Zhen Huang, Jia-Jie Sun, +8 authors, Hong Chen.
Sci Rep, 2014 Oct 14; 4. PMID: 25306978    Free PMC article.
Epigenetics as an answer to Darwin's "special difficulty".
Brian R Herb.
Front Genet, 2014 Oct 14; 5. PMID: 25309578    Free PMC article.
Divergence of gene body DNA methylation and evolution of plant duplicate genes.
Jun Wang, Nicholas C Marowsky, Chuanzhu Fan.
PLoS One, 2014 Oct 14; 9(10). PMID: 25310342    Free PMC article.
Unravelling the genomic targets of small molecules using high-throughput sequencing.
Raphaël Rodriguez, Kyle M Miller.
Nat Rev Genet, 2014 Oct 15; 15(12). PMID: 25311424
Review.
5-Aza-CdR delivers a gene body blow.
Sivakanthan Kasinathan, Steven Henikoff.
Cancer Cell, 2014 Oct 15; 26(4). PMID: 25314073    Free PMC article.
Evolving insights on how cytosine methylation affects protein-DNA binding.
Ana Carolina Dantas Machado, Tianyin Zhou, +5 authors, Remo Rohs.
Brief Funct Genomics, 2014 Oct 17; 14(1). PMID: 25319759    Free PMC article.
Review.
Bison: bisulfite alignment on nodes of a cluster.
Devon Patrick Ryan, Dan Ehninger.
BMC Bioinformatics, 2014 Oct 20; 15. PMID: 25326660    Free PMC article.
Relationship of DNA methylation and gene expression in idiopathic pulmonary fibrosis.
Ivana V Yang, Brent S Pedersen, +15 authors, David A Schwartz.
Am J Respir Crit Care Med, 2014 Oct 22; 190(11). PMID: 25333685    Free PMC article.
Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease.
Ralf Gilsbach, Sebastian Preissl, +10 authors, Lutz Hein.
Nat Commun, 2014 Oct 23; 5. PMID: 25335909    Free PMC article.
Highly Cited.
Facioscapulohumeral muscular dystrophy as a model for epigenetic regulation and disease.
Charis L Himeda, Takako I Jones, Peter L Jones.
Antioxid Redox Signal, 2014 Oct 23; 22(16). PMID: 25336259    Free PMC article.
Review.
Conserved and divergent patterns of DNA methylation in higher vertebrates.
Ning Jiang, Lin Wang, +3 authors, Zewei Luo.
Genome Biol Evol, 2014 Oct 31; 6(11). PMID: 25355807    Free PMC article.
MBD4 interacts with and recruits USP7 to heterochromatic foci.
Huan Meng, David J Harrison, Richard R Meehan.
J Cell Biochem, 2014 Nov 02; 116(3). PMID: 25358258    Free PMC article.
A comprehensive view of the epigenetic landscape part I: DNA methylation, passive and active DNA demethylation pathways and histone variants.
Anna Sadakierska-Chudy, Richard M Kostrzewa, Małgorzata Filip.
Neurotox Res, 2014 Nov 05; 27(1). PMID: 25362550    Free PMC article.
Review.
DNA methylation: old dog, new tricks?
Cornelia G Spruijt, Michiel Vermeulen.
Nat Struct Mol Biol, 2014 Nov 06; 21(11). PMID: 25372310
Epigenetic regulations through DNA methylation and hydroxymethylation: clues for early pregnancy in decidualization.
Fei Gao, Sanjoy K Das.
Biomol Concepts, 2014 Nov 06; 5(2). PMID: 25372745    Free PMC article.
Review.
Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.
Anders H Olsson, Petr Volkov, +6 authors, Charlotte Ling.
PLoS Genet, 2014 Nov 07; 10(11). PMID: 25375650    Free PMC article.
Highly Cited.
24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex.
Andrew S P Lim, Gyan P Srivastava, +7 authors, Philip L De Jager.
PLoS Genet, 2014 Nov 07; 10(11). PMID: 25375876    Free PMC article.
Alterations in gene expression and DNA methylation during murine and human lung alveolar septation.
Alain Cuna, Brian Halloran, +9 authors, Namasivayam Ambalavanan.
Am J Respir Cell Mol Biol, 2014 Nov 12; 53(1). PMID: 25387348    Free PMC article.
Network-mediated encoding of circadian time: the suprachiasmatic nucleus (SCN) from genes to neurons to circuits, and back.
Marco Brancaccio, Ryosuke Enoki, +3 authors, Abdelhalim Azzi.
J Neurosci, 2014 Nov 14; 34(46). PMID: 25392488    Free PMC article.
Review.
Mammalian Non-CpG Methylation: Stem Cells and Beyond.
Sara E Pinney.
Biology (Basel), 2014 Nov 14; 3(4). PMID: 25393317    Free PMC article.
Review.
MethHC: a database of DNA methylation and gene expression in human cancer.
Wei-Yun Huang, Sheng-Da Hsu, +4 authors, Hsien-Da Huang.
Nucleic Acids Res, 2014 Nov 16; 43(Database issue). PMID: 25398901    Free PMC article.
Highly Cited.
Meta-analysis of human methylation data for evidence of sex-specific autosomal patterns.
Nina S McCarthy, Phillip E Melton, +5 authors, Alex W Hewitt.
BMC Genomics, 2014 Nov 20; 15. PMID: 25406947    Free PMC article.
Genetics and epigenetics of alcohol dependence.
Vanessa Nieratschker, Anil Batra, Andreas J Fallgatter.
J Mol Psychiatry, 2013 Jan 01; 1(1). PMID: 25408904    Free PMC article.
Review.
The era of integrative genomics: more data or better methods?
Devin C Koestler, Meaghan J Jones, +2 authors, Michael Kobor.
Epigenomics, 2014 Nov 29; 6(5). PMID: 25431938    Free PMC article.
Cytogenetic evidences of genome rearrangement and differential epigenetic chromatin modification in the sea lamprey (Petromyzon marinus).
Lara Covelo-Soto, Paloma Morán, Juan J Pasantes, Concepción Pérez-García.
Genetica, 2014 Nov 30; 142(6). PMID: 25432678
Genome-wide DNA methylation analysis identifies a metabolic memory profile in patient-derived diabetic foot ulcer fibroblasts.
Lara K Park, Anna G Maione, +5 authors, Jonathan A Garlick.
Epigenetics, 2014 Dec 02; 9(10). PMID: 25437049    Free PMC article.
Molecular characteristics of pediatric high-grade gliomas.
Omar Chamdine, Amar Gajjar.
CNS Oncol, 2014 Dec 03; 3(6). PMID: 25438814    Free PMC article.
Review.
Combining MeDIP-seq and MRE-seq to investigate genome-wide CpG methylation.
Daofeng Li, Bo Zhang, Xiaoyun Xing, Ting Wang.
Methods, 2014 Dec 03; 72. PMID: 25448294    Free PMC article.
Detection of mismatched 5-hydroxymethyluracil in DNA by selective chemical labeling.
Miao Yu, Chun-Xiao Song, Chuan He.
Methods, 2014 Dec 03; 72. PMID: 25462560    Free PMC article.
A DNA methylation-based definition of biologically distinct breast cancer subtypes.
Olafur A Stefansson, Sebastian Moran, +9 authors, Manel Esteller.
Mol Oncol, 2014 Dec 04; 9(3). PMID: 25468711    Free PMC article.
Highly Cited.
Expanding epigenomics to archived FFPE tissues: an evaluation of DNA repair methodologies.
Erin M Siegel, Anders E Berglund, +5 authors, David Shibata.
Cancer Epidemiol Biomarkers Prev, 2014 Dec 05; 23(12). PMID: 25472669    Free PMC article.
Pan-cancer patterns of DNA methylation.
Tania Witte, Christoph Plass, Clarissa Gerhauser.
Genome Med, 2014 Dec 05; 6(8). PMID: 25473433    Free PMC article.
Comprehensive analysis of interacting proteins and genome-wide location studies of the Sas3-dependent NuA3 histone acetyltransferase complex.
Sara Vicente-Muñoz, Paco Romero, +3 authors, Mercè Pamblanco.
FEBS Open Bio, 2014 Dec 05; 4. PMID: 25473596    Free PMC article.
DNA methylation and differential gene regulation in photoreceptor cell death.
P Farinelli, A Perera, +8 authors, P A R Ekström.
Cell Death Dis, 2014 Dec 06; 5. PMID: 25476906    Free PMC article.
Protection of CpG islands against de novo DNA methylation during oogenesis is associated with the recognition site of E2f1 and E2f2.
Heba Saadeh, Reiner Schulz.
Epigenetics Chromatin, 2014 Dec 06; 7. PMID: 25478011    Free PMC article.
Epigenetic mechanisms in diabetic complications and metabolic memory.
Marpadga A Reddy, Erli Zhang, Rama Natarajan.
Diabetologia, 2014 Dec 08; 58(3). PMID: 25481708    Free PMC article.
Highly Cited. Review.
Genome-wide DNA methylation analysis in precursor B-cells.
Md Almamun, Benjamin T Levinson, +4 authors, Kristen H Taylor.
Epigenetics, 2014 Dec 09; 9(12). PMID: 25484143    Free PMC article.
An integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after training.
Maléne E Lindholm, Francesco Marabita, +4 authors, Carl Johan Sundberg.
Epigenetics, 2014 Dec 09; 9(12). PMID: 25484259    Free PMC article.
Site-specific methylation changes in the glucocorticoid receptor exon 1F promoter in relation to life adversity: systematic review of contributing factors.
Nikolaos P Daskalakis, Rachel Yehuda.
Front Neurosci, 2014 Dec 09; 8. PMID: 25484853    Free PMC article.
Review.
Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia.
Dan A Landau, Kendell Clement, +23 authors, Catherine J Wu.
Cancer Cell, 2014 Dec 10; 26(6). PMID: 25490447    Free PMC article.
Highly Cited.
Meta-analysis of human methylomes reveals stably methylated sequences surrounding CpG islands associated with high gene expression.
Rachel Edgar, Powell Patrick Cheng Tan, Elodie Portales-Casamar, Paul Pavlidis.
Epigenetics Chromatin, 2014 Dec 11; 7(1). PMID: 25493099    Free PMC article.
Genome-wide bisulfite sequencing in zygotes identifies demethylation targets and maps the contribution of TET3 oxidation.
Julian R Peat, Wendy Dean, +7 authors, Wolf Reik.
Cell Rep, 2014 Dec 17; 9(6). PMID: 25497087    Free PMC article.
Reduced TET2 function leads to T-cell lymphoma with follicular helper T-cell-like features in mice.
H Muto, M Sakata-Yanagimoto, +15 authors, S Chiba.
Blood Cancer J, 2014 Dec 17; 4. PMID: 25501021    Free PMC article.
DNA methylation transcriptionally regulates the putative tumor cell growth suppressor ZNF677 in non-small cell lung cancers.
Gerwin Heller, Corinna Altenberger, +15 authors, Sabine Zöchbauer-Müller.
Oncotarget, 2014 Dec 17; 6(1). PMID: 25504438    Free PMC article.
Bimodal signatures of germline methylation are linked with gene expression plasticity in the coral Acropora millepora.
Groves B Dixon, Line K Bay, Mikhail V Matz.
BMC Genomics, 2014 Dec 17; 15. PMID: 25511458    Free PMC article.
Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets.
Elin Hall, Petr Volkov, +6 authors, Charlotte Ling.
Genome Biol, 2014 Dec 18; 15(12). PMID: 25517766    Free PMC article.
Highly Cited.
Intraindividual variation and short-term temporal trend in DNA methylation of human blood.
Yurii B Shvetsov, Min-Ae Song, +4 authors, Herbert Yu.
Cancer Epidemiol Biomarkers Prev, 2014 Dec 30; 24(3). PMID: 25538225    Free PMC article.
Beyond receptors and signaling: epigenetic factors in the regulation of innate immunity.
Stuti Mehta, Kate L Jeffrey.
Immunol Cell Biol, 2015 Jan 07; 93(3). PMID: 25559622    Free PMC article.
Review.
Genome-wide methylation analysis in Silver-Russell syndrome patients.
A R Prickett, M Ishida, +7 authors, R J Oakey.
Hum Genet, 2015 Jan 08; 134(3). PMID: 25563730    Free PMC article.
Childhood maltreatment and stress-related psychopathology: the epigenetic memory hypothesis.
Pierre-Eric Lutz, Daniel Almeida, Laura M Fiori, Gustavo Turecki.
Curr Pharm Des, 2015 Jan 08; 21(11). PMID: 25564388    Free PMC article.
Review.
p53 binding to human genome: crowd control navigation in chromatin context.
Krassimira Botcheva.
Front Genet, 2015 Jan 08; 5. PMID: 25566329    Free PMC article.
Defining CD4 T cell memory by the epigenetic landscape of CpG DNA methylation.
H Kiyomi Komori, Traver Hart, +2 authors, Daniel R Salomon.
J Immunol, 2015 Jan 13; 194(4). PMID: 25576597    Free PMC article.
Relationship between expression and methylation of obesity-related genes in children.
Veronica Davé, Paul Yousefi, +2 authors, Nina Holland.
Mutagenesis, 2015 Jan 16; 30(3). PMID: 25589532    Free PMC article.
SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β.
Seo-Hyun Cho, Jason A Chen, +11 authors, Li Gan.
J Neurosci, 2015 Jan 16; 35(2). PMID: 25589773    Free PMC article.
Highly Cited.
Evolutionary consequences of DNA methylation on the GC content in vertebrate genomes.
Carina F Mugal, Peter F Arndt, Lena Holm, Hans Ellegren.
G3 (Bethesda), 2015 Jan 17; 5(3). PMID: 25591920    Free PMC article.
Function and information content of DNA methylation.
Dirk Schübeler.
Nature, 2015 Jan 17; 517(7534). PMID: 25592537
Highly Cited. Review.
Differential expression and DNA methylation of angiotensin type 1A receptors in vascular tissues during genetic hypertension development.
Fang Pei, Xinquan Wang, +5 authors, Chunyu Zeng.
Mol Cell Biochem, 2015 Jan 19; 402(1-2). PMID: 25596947
Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation.
Tuncay Baubec, Daniele F Colombo, +5 authors, Dirk Schübeler.
Nature, 2015 Jan 22; 520(7546). PMID: 25607372
Highly Cited.
Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements.
Weiwei Zhang, Tim D Spector, +2 authors, Barbara E Engelhardt.
Genome Biol, 2015 Jan 27; 16. PMID: 25616342    Free PMC article.
Highly Cited.
Age dependent changes in the LPS induced transcriptome of bovine dermal fibroblasts occurs without major changes in the methylome.
Benjamin B Green, Stephanie D McKay, David E Kerr.
BMC Genomics, 2015 Jan 28; 16. PMID: 25623529    Free PMC article.
Tissue-specific effects of genetic and epigenetic variation on gene regulation and splicing.
Maria Gutierrez-Arcelus, Halit Ongen, +18 authors, Emmanouil T Dermitzakis.
PLoS Genet, 2015 Jan 31; 11(1). PMID: 25634236    Free PMC article.
Highly Cited.
Inferring cell differentiation processes based on phylogenetic analysis of genome-wide epigenetic information: hematopoiesis as a model case.
Kanako O Koyanagi.
Genome Biol Evol, 2015 Feb 02; 7(3). PMID: 25638259    Free PMC article.
[Genetics of atopic eczema. An update].
E Rodríguez, S Weidinger.
Hautarzt, 2015 Feb 05; 66(2). PMID: 25648547
Methylomic trajectories across human fetal brain development.
Helen Spiers, Eilis Hannon, +5 authors, Jonathan Mill.
Genome Res, 2015 Feb 05; 25(3). PMID: 25650246    Free PMC article.
Highly Cited.
Transcription driven somatic DNA methylation within the imprinted Gnas cluster.
Stuti Mehta, Christine M Williamson, +4 authors, Jo Peters.
PLoS One, 2015 Feb 07; 10(2). PMID: 25659103    Free PMC article.
Discordance of DNA methylation variance between two accessible human tissues.
Ruiwei Jiang, Meaghan J Jones, +4 authors, Michael S Kobor.
Sci Rep, 2015 Feb 11; 5. PMID: 25660083    Free PMC article.
KLLN epigenotype-phenotype associations in Cowden syndrome.
Emily A Nizialek, Jessica L Mester, +2 authors, Charis Eng.
Eur J Hum Genet, 2015 Feb 12; 23(11). PMID: 25669429    Free PMC article.
Chromatin modifications and genomic contexts linked to dynamic DNA methylation patterns across human cell types.
Haidan Yan, Dongwei Zhang, +7 authors, Yan Zhang.
Sci Rep, 2015 Feb 13; 5. PMID: 25673498    Free PMC article.
Discovery of transcription factors and regulatory regions driving in vivo tumor development by ATAC-seq and FAIRE-seq open chromatin profiling.
Kristofer Davie, Jelle Jacobs, +4 authors, Stein Aerts.
PLoS Genet, 2015 Feb 14; 11(2). PMID: 25679813    Free PMC article.
Highly Cited.
DNA methylome and transcriptome sequencing in human ovarian granulosa cells links age-related changes in gene expression to gene body methylation and 3'-end GC density.
Bo Yu, Valya R Russanova, +7 authors, Bruce H Howard.
Oncotarget, 2015 Feb 17; 6(6). PMID: 25682867    Free PMC article.
Integrative analysis of 111 reference human epigenomes.
Roadmap Epigenomics Consortium, Anshul Kundaje, +93 authors, Manolis Kellis.
Nature, 2015 Feb 20; 518(7539). PMID: 25693563    Free PMC article.
Highly Cited.
Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos.
Hyung Joo Lee, Rebecca F Lowdon, +5 authors, Ting Wang.
Nat Commun, 2015 Feb 24; 6. PMID: 25697895    Free PMC article.
Mining for viral fragments in methylation enriched sequencing data.
Klaas Mensaert, Wim Van Criekinge, +4 authors, Tim De Meyer.
Front Genet, 2015 Feb 24; 6. PMID: 25699076    Free PMC article.
Identification and characterization of methylation-dependent/independent DNA regulatory elements in the human SLC9B1 gene.
Priya L Kumar, Paul F James.
Gene, 2015 Feb 24; 561(2). PMID: 25701605    Free PMC article.
A meta-analysis on age-associated changes in blood DNA methylation: results from an original analysis pipeline for Infinium 450k data.
Maria Giulia Bacalini, Alessio Boattini, +15 authors, Paolo Garagnani.
Aging (Albany NY), 2015 Feb 24; 7(2). PMID: 25701668    Free PMC article.
Epigenome engineering in cancer: fairytale or a realistic path to the clinic?
Fahimeh Falahi, Agustin Sgro, Pilar Blancafort.
Front Oncol, 2015 Feb 24; 5. PMID: 25705610    Free PMC article.
Review.
Genome-wide profiling of DNA methylation provides insights into epigenetic regulation of fungal development in a plant pathogenic fungus, Magnaporthe oryzae.
Junhyun Jeon, Jaeyoung Choi, +4 authors, Yong-Hwan Lee.
Sci Rep, 2015 Feb 25; 5. PMID: 25708804    Free PMC article.
Epigenetic alterations in human parathyroid tumors.
Chiara Verdelli, Irene Forno, Valentina Vaira, Sabrina Corbetta.
Endocrine, 2015 Feb 28; 49(2). PMID: 25722013
Review.
Base-resolution methylation patterns accurately predict transcription factor bindings in vivo.
Tianlei Xu, Ben Li, +8 authors, Zhaohui S Qin.
Nucleic Acids Res, 2015 Feb 28; 43(5). PMID: 25722376    Free PMC article.
Circuit- and Diagnosis-Specific DNA Methylation Changes at γ-Aminobutyric Acid-Related Genes in Postmortem Human Hippocampus in Schizophrenia and Bipolar Disorder.
W Brad Ruzicka, Sivan Subburaju, Francine M Benes.
JAMA Psychiatry, 2015 Mar 05; 72(6). PMID: 25738424    Free PMC article.
Advancements in the delivery of epigenetic drugs.
Samantha A Cramer, Isaac M Adjei, Vinod Labhasetwar.
Expert Opin Drug Deliv, 2015 Mar 06; 12(9). PMID: 25739728    Free PMC article.
Review.
Synthetic epigenetics-towards intelligent control of epigenetic states and cell identity.
Tomasz P Jurkowski, Mirunalini Ravichandran, Peter Stepper.
Clin Epigenetics, 2015 Mar 06; 7. PMID: 25741388    Free PMC article.
Enhanced reduced representation bisulfite sequencing for assessment of DNA methylation at base pair resolution.
Francine E Garrett-Bakelman, Caroline K Sheridan, +6 authors, Ari M Melnick.
J Vis Exp, 2015 Mar 06; (96). PMID: 25742437    Free PMC article.
The role of DNA methylation in directing the functional organization of the cancer epigenome.
Fides D Lay, Yaping Liu, +4 authors, Benjamin P Berman.
Genome Res, 2015 Mar 10; 25(4). PMID: 25747664    Free PMC article.
An epigenetic regulator: methyl-CpG-binding domain protein 1 (MBD1).
Lu Li, Bi-Feng Chen, Wai-Yee Chan.
Int J Mol Sci, 2015 Mar 10; 16(3). PMID: 25751725    Free PMC article.
Review.
Dissecting the behavior and function of MBD3 in DNA methylation homeostasis by single-molecule spectroscopy and microscopy.
Yi Cui, Joseph Irudayaraj.
Nucleic Acids Res, 2015 Mar 11; 43(6). PMID: 25753672    Free PMC article.
Epigenetics as an answer to Darwin's "special difficulty," Part 2: natural selection of metastable epialleles in honeybee castes.
Douglas M Ruden, Pablo E Cingolani, +6 authors, Xiangyi Lu.
Front Genet, 2015 Mar 12; 6. PMID: 25759717    Free PMC article.
Review.
A diverse epigenetic landscape at human exons with implication for expression.
Meromit Singer, Idit Kosti, Lior Pachter, Yael Mandel-Gutfreund.
Nucleic Acids Res, 2015 Mar 15; 43(7). PMID: 25765649    Free PMC article.
DNA methylation and childhood asthma in the inner city.
Ivana V Yang, Brent S Pedersen, +17 authors, David A Schwartz.
J Allergy Clin Immunol, 2015 Mar 15; 136(1). PMID: 25769910    Free PMC article.
Highly Cited.
WGBSSuite: simulating whole-genome bisulphite sequencing data and benchmarking differential DNA methylation analysis tools.
Owen J L Rackham, Petros Dellaportas, Enrico Petretto, Leonardo Bottolo.
Bioinformatics, 2015 Mar 18; 31(14). PMID: 25777524    Free PMC article.
Artificial light at night: melatonin as a mediator between the environment and epigenome.
Abraham Haim, Abed E Zubidat.
Philos Trans R Soc Lond B Biol Sci, 2015 Mar 18; 370(1667). PMID: 25780234    Free PMC article.
Review.
The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.
I Dahlman, I Sinha, +9 authors, P Arner.
Int J Obes (Lond), 2015 Mar 19; 39(6). PMID: 25783037
Increased DNA methylation of the SLC30A8 gene promoter is associated with type 2 diabetes in a Malay population.
Norhashimah Abu Seman, Wan Nazaimoon Wan Mohamud, +2 authors, Harvest F Gu.
Clin Epigenetics, 2015 Mar 21; 7. PMID: 25793017    Free PMC article.
Emerging technologies for studying DNA methylation for the molecular diagnosis of cancer.
Diego M Marzese, Dave Sb Hoon.
Expert Rev Mol Diagn, 2015 Mar 24; 15(5). PMID: 25797072    Free PMC article.
Review.
Personal genomes, quantitative dynamic omics and personalized medicine.
George I Mias, Michael Snyder.
Quant Biol, 2013 Mar 01; 1(1). PMID: 25798291    Free PMC article.
Methylation-associated partial down-regulation of mesothelin causes resistance to anti-mesothelin immunotoxins in a pancreatic cancer cell line.
Kevin Hollevoet, Emily Mason-Osann, Fabian Müller, Ira Pastan.
PLoS One, 2015 Mar 25; 10(3). PMID: 25803818    Free PMC article.
Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8+ T cell responses.
Bethany Winans, Anusha Nagari, +5 authors, B Paige Lawrence.
J Immunol, 2015 Mar 27; 194(9). PMID: 25810390    Free PMC article.
Integrative epigenomic analysis of differential DNA methylation in urothelial carcinoma.
Mattias Aine, Gottfrid Sjödahl, +4 authors, Mattias Höglund.
Genome Med, 2015 Mar 27; 7(1). PMID: 25810763    Free PMC article.
Parallel epigenomic and transcriptomic responses to viral infection in honey bees (Apis mellifera).
David A Galbraith, Xingyu Yang, +2 authors, Christina Grozinger.
PLoS Pathog, 2015 Mar 27; 11(3). PMID: 25811620    Free PMC article.
Quantitative DNA methylation analysis of candidate genes in cervical cancer.
Erin M Siegel, Bridget M Riggs, +3 authors, Kevin D Brown.
PLoS One, 2015 Apr 01; 10(3). PMID: 25826459    Free PMC article.
Correlation between Reversal of DNA Methylation and Clinical Symptoms in Psoriatic Epidermis Following Narrow-Band UVB Phototherapy.
Xiaolian Gu, Elisabet Nylander, +2 authors, Karin Nylander.
J Invest Dermatol, 2015 Apr 02; 135(8). PMID: 25830654    Free PMC article.
Pathogenesis beyond the cancer clone(s) in multiple myeloma.
Giada Bianchi, Nikhil C Munshi.
Blood, 2015 Apr 04; 125(20). PMID: 25838343    Free PMC article.
Highly Cited. Review.
Endothelial epigenetics in biomechanical stress: disturbed flow-mediated epigenomic plasticity in vivo and in vitro.
Yi-Zhou Jiang, Elisabetta Manduchi, Juan M Jiménez, Peter F Davies.
Arterioscler Thromb Vasc Biol, 2015 Apr 04; 35(6). PMID: 25838424    Free PMC article.
Review.
A comparison of genome-wide DNA methylation patterns between different vascular tissues from patients with coronary heart disease.
Maria S Nazarenko, Anton V Markov, +7 authors, Valery P Puzyrev.
PLoS One, 2015 Apr 10; 10(4). PMID: 25856389    Free PMC article.
Using epigenomics data to predict gene expression in lung cancer.
Jeffery Li, Travers Ching, Sijia Huang, Lana X Garmire.
BMC Bioinformatics, 2015 Apr 11; 16 Suppl 5. PMID: 25861082    Free PMC article.
Multiplex bisulfite PCR resequencing of clinical FFPE DNA.
Darren Korbie, Erica Lin, +4 authors, Matt Trau.
Clin Epigenetics, 2015 Apr 11; 7. PMID: 25861392    Free PMC article.
TALE-mediated epigenetic suppression of CDKN2A increases replication in human fibroblasts.
Diana L Bernstein, John E Le Lay, Elena G Ruano, Klaus H Kaestner.
J Clin Invest, 2015 Apr 14; 125(5). PMID: 25866970    Free PMC article.
Highly Cited.
Drinking beyond a lifetime: New and emerging insights into paternal alcohol exposure on subsequent generations.
Andrey Finegersh, Gregory R Rompala, David I K Martin, Gregg E Homanics.
Alcohol, 2015 Apr 19; 49(5). PMID: 25887183    Free PMC article.
Review.
Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression.
Saara Marttila, Laura Kananen, +6 authors, Mikko Hurme.
BMC Genomics, 2015 Apr 19; 16. PMID: 25888029    Free PMC article.
DNA methylation, its mediators and genome integrity.
Huan Meng, Ying Cao, +4 authors, Liu Cao.
Int J Biol Sci, 2015 Apr 22; 11(5). PMID: 25892967    Free PMC article.
Review.
Targeted epigenome editing of an endogenous locus with chromatin modifiers is not stably maintained.
Goran Kungulovski, Suneetha Nunna, +3 authors, Albert Jeltsch.
Epigenetics Chromatin, 2015 Apr 23; 8. PMID: 25901185    Free PMC article.
A pooling-based approach to mapping genetic variants associated with DNA methylation.
Irene M Kaplow, Julia L MacIsaac, +3 authors, Hunter B Fraser.
Genome Res, 2015 Apr 26; 25(6). PMID: 25910490    Free PMC article.
DNA methylation and healthy human aging.
Meaghan J Jones, Sarah J Goodman, Michael S Kobor.
Aging Cell, 2015 Apr 29; 14(6). PMID: 25913071    Free PMC article.
Highly Cited. Review.
Genetic differences and aberrant methylation in the apelin system predict the risk of high-altitude pulmonary edema.
Aastha Mishra, Samantha Kohli, +3 authors, M A Qadar Pasha.
Proc Natl Acad Sci U S A, 2015 Apr 29; 112(19). PMID: 25918383    Free PMC article.
Genome-wide epigenetic and proteomic analysis reveals altered Notch signaling in EPC dysfunction.
Jamie R Karcher, Brian R Hoffmann, +3 authors, Andrew S Greene.
Physiol Rep, 2015 Apr 30; 3(4). PMID: 25921777    Free PMC article.
N6-methyldeoxyadenosine marks active transcription start sites in Chlamydomonas.
Ye Fu, Guan-Zheng Luo, +11 authors, Chuan He.
Cell, 2015 May 06; 161(4). PMID: 25936837    Free PMC article.
Highly Cited.
Genome-wide methylation profiling of schizophrenia.
B Rukova, R Staneva, +3 authors, D Toncheva.
Balkan J Med Genet, 2015 May 06; 17(2). PMID: 25937794    Free PMC article.
Short-term exposure to engineered nanomaterials affects cellular epigenome.
Xiaoyan Lu, Isabelle R Miousse, +3 authors, Philip Demokritou.
Nanotoxicology, 2015 May 06; 10(2). PMID: 25938281    Free PMC article.
Epigenetic mechanisms in the pathophysiology of psychotic disorders.
W Brad Ruzicka.
Harv Rev Psychiatry, 2015 May 07; 23(3). PMID: 25943315    Free PMC article.
DNA methylation analysis of phenotype specific stratified Indian population.
Harish Rotti, Sandeep Mallya, +21 authors, Kapaettu Satyamoorthy.
J Transl Med, 2015 May 09; 13. PMID: 25952924    Free PMC article.
Developmental programming of hypothalamic neuronal circuits: impact on energy balance control.
Thanuja Gali Ramamoorthy, Ghazala Begum, Erika Harno, Anne White.
Front Neurosci, 2015 May 09; 9. PMID: 25954145    Free PMC article.
Review.
Migration-related phenotypic divergence is associated with epigenetic modifications in rainbow trout.
Melinda R Baerwald, Mariah H Meek, +6 authors, Krista M Nichols.
Mol Ecol, 2015 May 12; 25(8). PMID: 25958780    Free PMC article.
Analysis of DNA methylation and gene expression in radiation-resistant head and neck tumors.
Xiaofei Chen, Liang Liu, +7 authors, Cristina M Furdui.
Epigenetics, 2015 May 12; 10(6). PMID: 25961636    Free PMC article.
miR-29s: a family of epi-miRNAs with therapeutic implications in hematologic malignancies.
Nicola Amodio, Marco Rossi, +4 authors, Pierfrancesco Tassone.
Oncotarget, 2015 May 15; 6(15). PMID: 25968566    Free PMC article.
Highly Cited. Review.
Epigenetic control of interferon-gamma expression in CD8 T cells.
Patrícia S de Araújo-Souza, Steffi C H Hanschke, João P B Viola.
J Immunol Res, 2015 May 15; 2015. PMID: 25973438    Free PMC article.
Review.
Epigenetic mechanisms underlying the aberrant catabolic and anabolic activities of osteoarthritic chondrocytes.
Mingcai Zhang, Brian Egan, Jinxi Wang.
Int J Biochem Cell Biol, 2015 May 16; 67. PMID: 25975825    Free PMC article.
Review.
Association of Protein Phosphatase PPM1G With Alcohol Use Disorder and Brain Activity During Behavioral Control in a Genome-Wide Methylation Analysis.
Barbara Ruggeri, Charlotte Nymberg, +39 authors, IMAGEN Consortium.
Am J Psychiatry, 2015 May 20; 172(6). PMID: 25982659    Free PMC article.
The potential role of DNA methylation in abdominal aortic aneurysms.
Evan J Ryer, Kaitryn E Ronning, +9 authors, Gerard Tromp.
Int J Mol Sci, 2015 May 21; 16(5). PMID: 25993294    Free PMC article.
Recent developments in epigenetics of acute and chronic kidney diseases.
Marpadga A Reddy, Rama Natarajan.
Kidney Int, 2015 May 21; 88(2). PMID: 25993323    Free PMC article.
Review.
Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites.
Fiorella C Grandi, James M Rosser, +10 authors, Wenfeng An.
Genome Res, 2015 May 23; 25(8). PMID: 25995269    Free PMC article.
Epigenetic mechanisms in cancer: push and pull between kneaded erasers and fate writers.
Ammad Ahmad Farooqi, Jen-Yang Tang, +8 authors, Hsueh-Wei Chang.
Int J Nanomedicine, 2015 May 23; 10. PMID: 25995628    Free PMC article.
Review.
Regulators associated with clinical outcomes revealed by DNA methylation data in breast cancer.
Matthew H Ung, Frederick S Varn, Shaoke Lou, Chao Cheng.
PLoS Comput Biol, 2015 May 23; 11(5). PMID: 25996148    Free PMC article.
Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1.
Levani Zandarashvili, Mark A White, Alexandre Esadze, Junji Iwahara.
FEBS Lett, 2015 May 24; 589(15). PMID: 25999311    Free PMC article.
Tobacco smoking is associated with methylation of genes related to coronary artery disease.
Rebecca V Steenaard, Symen Ligthart, +6 authors, Abbas Dehghan.
Clin Epigenetics, 2015 May 28; 7. PMID: 26015811    Free PMC article.
Whole genome methylation analyses of schizophrenia patients before and after treatment.
Blaga Rukova, Rada Staneva, +3 authors, Draga Toncheva.
Biotechnol Biotechnol Equip, 2015 May 29; 28(3). PMID: 26019538    Free PMC article.
Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants.
Fiona Allum, Xiaojian Shao, +22 authors, Elin Grundberg.
Nat Commun, 2015 May 30; 6. PMID: 26021296    Free PMC article.
A systematic study of normalization methods for Infinium 450K methylation data using whole-genome bisulfite sequencing data.
Ting Wang, Weihua Guan, +5 authors, Wei Chen.
Epigenetics, 2015 Jun 04; 10(7). PMID: 26036609    Free PMC article.
Genome-Wide DNA Methylation Profiling Reveals Epigenetic Changes in the Rat Nucleus Accumbens Associated With Cross-Generational Effects of Adolescent THC Exposure.
Corey T Watson, Henrietta Szutorisz, +4 authors, Yasmin L Hurd.
Neuropsychopharmacology, 2015 Jun 06; 40(13). PMID: 26044905    Free PMC article.
Aberrant Cosmc genes result in Tn antigen expression in human colorectal carcinoma cell line HT-29.
Xiaofeng Yu, Zhenzhen Du, +3 authors, Tao Hu.
Int J Clin Exp Pathol, 2015 Jun 06; 8(3). PMID: 26045765    Free PMC article.
A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development.
Walfred W C Tang, Sabine Dietmann, +6 authors, M Azim Surani.
Cell, 2015 Jun 06; 161(6). PMID: 26046444    Free PMC article.
Highly Cited.
Lead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cells and umbilical cord blood.
Arko Sen, Pablo Cingolani, +6 authors, Douglas M Ruden.
Epigenetics, 2015 Jun 06; 10(7). PMID: 26046694    Free PMC article.
Can we observe epigenetic effects on human brain function?
Yuliya S Nikolova, Ahmad R Hariri.
Trends Cogn Sci, 2015 Jun 09; 19(7). PMID: 26051383    Free PMC article.
Review.
Epigenetic Modifications of the PGC-1α Promoter during Exercise Induced Expression in Mice.
Timothy L Lochmann, Ravindar R Thomas, James P Bennett, Shirley M Taylor.
PLoS One, 2015 Jun 09; 10(6). PMID: 26053857    Free PMC article.
DNA methylation at IL32 in juvenile idiopathic arthritis.
Braydon Meyer, Raul A Chavez, +7 authors, Justine A Ellis.
Sci Rep, 2015 Jun 10; 5. PMID: 26057774    Free PMC article.
Rett syndrome: disruption of epigenetic control of postnatal neurological functions.
Amy E Pohodich, Huda Y Zoghbi.
Hum Mol Genet, 2015 Jun 11; 24(R1). PMID: 26060191    Free PMC article.
Review.
Methyl supplementation attenuates cocaine-seeking behaviors and cocaine-induced c-Fos activation in a DNA methylation-dependent manner.
Katherine N Wright, Fiona Hollis, +9 authors, Mohamed Kabbaj.
J Neurosci, 2015 Jun 13; 35(23). PMID: 26063926    Free PMC article.
Epigenetic Changes during Hepatic Stellate Cell Activation.
Silke Götze, Eva C Schumacher, Claus Kordes, Dieter Häussinger.
PLoS One, 2015 Jun 13; 10(6). PMID: 26065684    Free PMC article.
Low-protein diet fed to crossbred sows during pregnancy and lactation enhances myostatin gene expression through epigenetic regulation in skeletal muscle of weaning piglets.
Yimin Jia, Guichao Gao, +3 authors, Ruqian Zhao.
Eur J Nutr, 2015 Jun 13; 55(3). PMID: 26066356
A parallel and sensitive software tool for methylation analysis on multicore platforms.
Joaquín Tárraga, Mariano Pérez, +3 authors, Joaquín Dopazo.
Bioinformatics, 2015 Jun 13; 31(19). PMID: 26069264    Free PMC article.
DNA Methylation Affects the SP1-regulated Transcription of FOXF2 in Breast Cancer Cells.
Hong-Pan Tian, Shu-Min Lun, +5 authors, Yu-Mei Feng.
J Biol Chem, 2015 Jun 14; 290(31). PMID: 26070560    Free PMC article.
Multiblock discriminant analysis for integrative genomic study.
Mingon Kang, Dong-Chul Kim, Chunyu Liu, Jean Gao.
Biomed Res Int, 2015 Jun 16; 2015. PMID: 26075260    Free PMC article.
Early life lead exposure causes gender-specific changes in the DNA methylation profile of DNA extracted from dried blood spots.
Arko Sen, Nicole Heredia, +6 authors, Douglas M Ruden.
Epigenomics, 2015 Jun 17; 7(3). PMID: 26077427    Free PMC article.
Non-CG Methylation in the Human Genome.
Yupeng He, Joseph R Ecker.
Annu Rev Genomics Hum Genet, 2015 Jun 17; 16. PMID: 26077819    Free PMC article.
Highly Cited. Review.
MBRidge: an accurate and cost-effective method for profiling DNA methylome at single-base resolution.
Wanshi Cai, Fengbiao Mao, +4 authors, Zhong Sheng Sun.
J Mol Cell Biol, 2015 Jun 17; 7(4). PMID: 26078362    Free PMC article.
Effects of Laser Printer-Emitted Engineered Nanoparticles on Cytotoxicity, Chemokine Expression, Reactive Oxygen Species, DNA Methylation, and DNA Damage: A Comprehensive in Vitro Analysis in Human Small Airway Epithelial Cells, Macrophages, and Lymphoblasts.
Sandra V Pirela, Isabelle R Miousse, +7 authors, Philip Demokritou.
Environ Health Perspect, 2015 Jun 17; 124(2). PMID: 26080392    Free PMC article.
Associations between genetic variation in one-carbon metabolism and LINE-1 DNA methylation in histologically normal breast tissues.
Adana A M Llanos, Catalin Marian, +8 authors, Peter G Shields.
Epigenetics, 2015 Jun 20; 10(8). PMID: 26090795    Free PMC article.
Modelling the conditional regulatory activity of methylated and bivalent promoters.
David M Budden, Daniel G Hurley, Edmund J Crampin.
Epigenetics Chromatin, 2015 Jun 23; 8. PMID: 26097508    Free PMC article.
DNA methyltransferase 3b silencing affects locus-specific DNA methylation and inhibits proliferation, migration and invasion in human hepatocellular carcinoma SMMC-7721 and BEL-7402 cells.
Jia-Chen Wang, Zhao Wang, +2 authors, Jia-Xiang Wang.
Oncol Lett, 2015 Jul 03; 9(6). PMID: 26137097    Free PMC article.
Epigenetic regulators as promising therapeutic targets in acute myeloid leukemia.
Paolo Gallipoli, George Giotopoulos, Brian J P Huntly.
Ther Adv Hematol, 2015 Jul 03; 6(3). PMID: 26137202    Free PMC article.
Review.
Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use.
Shaunna L Clark, Karolina A Aberg, +12 authors, Edwin J C G van den Oord.
Alcohol Clin Exp Res, 2015 Jul 07; 39(8). PMID: 26146898    Free PMC article.
Hepatitis viruses exploitation of host DNA methyltransferases functions.
Valerio Pazienza, Concetta Panebianco, Angelo Andriulli.
Clin Exp Med, 2015 Jul 08; 16(3). PMID: 26148656
Review.
Arterial endothelial methylome: differential DNA methylation in athero-susceptible disturbed flow regions in vivo.
Yi-Zhou Jiang, Elisabetta Manduchi, Christian J Stoeckert, Peter F Davies.
BMC Genomics, 2015 Jul 08; 16. PMID: 26148682    Free PMC article.
DNA methylation and gene expression in Mimulus guttatus.
Jack M Colicchio, Fumihito Miura, +2 authors, Lena C Hileman.
BMC Genomics, 2015 Jul 08; 16. PMID: 26148779    Free PMC article.
Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease.
Jingzhong Ding, Lindsay M Reynolds, +26 authors, Yongmei Liu.
Diabetes, 2015 Jul 15; 64(10). PMID: 26153245    Free PMC article.
RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation.
Yanan Yue, Jianzhao Liu, Chuan He.
Genes Dev, 2015 Jul 15; 29(13). PMID: 26159994    Free PMC article.
Highly Cited. Review.
BSPAT: a fast online tool for DNA methylation co-occurrence pattern analysis based on high-throughput bisulfite sequencing data.
Ke Hu, Angela H Ting, Jing Li.
BMC Bioinformatics, 2015 Jul 15; 16. PMID: 26163275    Free PMC article.
The interplay between DNA methylation and sequence divergence in recent human evolution.
Irene Hernando-Herraez, Holger Heyn, +6 authors, Tomas Marques-Bonet.
Nucleic Acids Res, 2015 Jul 15; 43(17). PMID: 26170231    Free PMC article.
Epigenetics in lung fibrosis: from pathobiology to treatment perspective.
Britney A Helling, Ivana V Yang.
Curr Opin Pulm Med, 2015 Jul 16; 21(5). PMID: 26176965    Free PMC article.
Review.
Detection of differentially methylated regions from whole-genome bisulfite sequencing data without replicates.
Hao Wu, Tianlei Xu, +6 authors, Karen N Conneely.
Nucleic Acids Res, 2015 Jul 18; 43(21). PMID: 26184873    Free PMC article.
Highly Cited.
Altering TET dioxygenase levels within physiological range affects DNA methylation dynamics of HEK293 cells.
Christian Grosser, Nicholas Wagner, Katrin Grothaus, Bernhard Horsthemke.
Epigenetics, 2015 Jul 18; 10(9). PMID: 26186463    Free PMC article.
Transcriptomic and epigenetic analyses reveal a gender difference in aging-associated inflammation: the Vitality 90+ study.
T Nevalainen, L Kananen, +4 authors, J Jylhävä.
Age (Dordr), 2015 Jul 21; 37(4). PMID: 26188803    Free PMC article.
Epigenetic regulatory functions of DNA modifications: 5-methylcytosine and beyond.
Achim Breiling, Frank Lyko.
Epigenetics Chromatin, 2015 Jul 22; 8. PMID: 26195987    Free PMC article.
Highly Cited. Review.
PIWI-interacting RNA 021285 is involved in breast tumorigenesis possibly by remodeling the cancer epigenome.
Alan Fu, Daniel I Jacobs, +2 authors, Yong Zhu.
Carcinogenesis, 2015 Jul 27; 36(10). PMID: 26210741    Free PMC article.
DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer.
Kevin C Johnson, Devin C Koestler, +6 authors, Brock C Christensen.
Clin Epigenetics, 2015 Jul 28; 7. PMID: 26213588    Free PMC article.
Demethylation of tumor necrosis factor-α converting enzyme promoter associated with high hepatitis B e antigen level in chronic hepatitis B.
Zhen-Li Wang, Shuai Gao, +4 authors, Kai Wang.
World J Gastroenterol, 2015 Jul 29; 21(27). PMID: 26217090    Free PMC article.
An Epigenetic Mechanism of High Gdnf Transcription in Glioma Cells Revealed by Specific Sequence Methylation.
Bao-Le Zhang, Jie Liu, +5 authors, Dian-Shuai Gao.
Mol Neurobiol, 2015 Aug 02; 53(7). PMID: 26232065
MECP2 disorders: from the clinic to mice and back.
Laura Marie Lombardi, Steven Andrew Baker, Huda Yahya Zoghbi.
J Clin Invest, 2015 Aug 04; 125(8). PMID: 26237041    Free PMC article.
Highly Cited. Review.
Aberrant expression and localization of deoxyribonucleic acid methyltransferase 3B in endometriotic stromal cells.
Matthew T Dyson, Toshiyuki Kakinuma, +5 authors, Serdar E Bulun.
Fertil Steril, 2015 Aug 05; 104(4). PMID: 26239024    Free PMC article.
Systematically Prioritizing Functional Differentially Methylated Regions (fDMRs) by Integrating Multi-omics Data in Colorectal Cancer.
Huihui Fan, Hongying Zhao, +7 authors, Xia Li.
Sci Rep, 2015 Aug 05; 5. PMID: 26239918    Free PMC article.
Epigenetic Modification of Mitochondrial DNA in the Development of Diabetic Retinopathy.
Manish Mishra, Renu A Kowluru.
Invest Ophthalmol Vis Sci, 2015 Aug 05; 56(9). PMID: 26241401    Free PMC article.
Translational genomics for plant breeding with the genome sequence explosion.
Yang Jae Kang, Taeyoung Lee, +5 authors, Suk-Ha Lee.
Plant Biotechnol J, 2015 Aug 14; 14(4). PMID: 26269219    Free PMC article.
Review.
Reporter Gene Silencing in Targeted Mouse Mutants Is Associated with Promoter CpG Island Methylation.
Julia V Kirov, Michael Adkisson, +6 authors, David B West.
PLoS One, 2015 Aug 15; 10(8). PMID: 26275310    Free PMC article.
GC skew defines distinct RNA polymerase pause sites in CpG island promoters.
Wendy A Kellner, Joshua S K Bell, Paula M Vertino.
Genome Res, 2015 Aug 16; 25(11). PMID: 26275623    Free PMC article.
Vascular Smooth Muscle as a Target for Novel Therapeutics.
Karen E Porter, Kirsten Riches.
Curr Diab Rep, 2015 Aug 19; 15(10). PMID: 26277484
Review.
Response of transposable elements to environmental stressors.
Isabelle R Miousse, Marie-Cecile G Chalbot, +3 authors, Igor Koturbash.
Mutat Res Rev Mutat Res, 2015 Aug 19; 765. PMID: 26281766    Free PMC article.
Review.
Integrative analysis of methylome and transcriptome in human blood identifies extensive sex- and immune cell-specific differentially methylated regions.
Shimrat Mamrut, Nili Avidan, +4 authors, Ariel Miller.
Epigenetics, 2015 Aug 21; 10(10). PMID: 26291385    Free PMC article.
Pharmacokinetics and Pharmacodynamics with Extended Dosing of CC-486 in Patients with Hematologic Malignancies.
Eric Laille, Tao Shi, +6 authors, Kyle J MacBeth.
PLoS One, 2015 Aug 22; 10(8). PMID: 26296092    Free PMC article.
DNA methylation pathways and their crosstalk with histone methylation.
Jiamu Du, Lianna M Johnson, Steven E Jacobsen, Dinshaw J Patel.
Nat Rev Mol Cell Biol, 2015 Aug 22; 16(9). PMID: 26296162    Free PMC article.
Highly Cited. Review.
Understanding the pathogenesis of abdominal aortic aneurysms.
Helena Kuivaniemi, Evan J Ryer, James R Elmore, Gerard Tromp.
Expert Rev Cardiovasc Ther, 2015 Aug 27; 13(9). PMID: 26308600    Free PMC article.
Review.
The Triple-Code Model for Pancreatic Cancer: Cross Talk Among Genetics, Epigenetics, and Nuclear Structure.
Gwen A Lomberk, Raul Urrutia.
Surg Clin North Am, 2015 Sep 01; 95(5). PMID: 26315515    Free PMC article.
Review.
DNA-Methylation Patterns in Trisomy 21 Using Cells from Monozygotic Twins.
M Reza Sailani, Federico A Santoni, +12 authors, Stylianos E Antonarakis.
PLoS One, 2015 Sep 01; 10(8). PMID: 26317209    Free PMC article.
Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease.
Tommy Pacana, Sophie Cazanave, +5 authors, Arun J Sanyal.
PLoS One, 2015 Sep 01; 10(8). PMID: 26322888    Free PMC article.
Assessment of global DNA methylation in peripheral blood cell subpopulations of early rheumatoid arthritis before and after methotrexate.
María C de Andres, Eva Perez-Pampin, +4 authors, Antonio Gonzalez.
Arthritis Res Ther, 2015 Sep 04; 17. PMID: 26330155    Free PMC article.
Charting oxidized methylcytosines at base resolution.
Hao Wu, Yi Zhang.
Nat Struct Mol Biol, 2015 Sep 04; 22(9). PMID: 26333715    Free PMC article.
Peroxisome proliferator activated receptor γ protein expression is asymmetrically distributed in primary lung tumor and metastatic to lung osteosarcoma samples and does not correlate with gene methylation.
Chamisa L Herrera, Dae Young Kim, Senthil R Kumar, Jeffrey N Bryan.
BMC Vet Res, 2015 Sep 04; 11. PMID: 26334880    Free PMC article.
Methylation-dependent and independent regulatory regions in the Na,K-ATPase alpha4 (Atp1a4) gene may impact its testis-specific expression.
Deepti L Kumar, Priya L Kumar, Paul F James.
Gene, 2015 Sep 08; 575(2 Pt 1). PMID: 26343794    Free PMC article.
The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women.
Peter Arner, Indranil Sinha, +3 authors, Ingrid Dahlman.
Clin Epigenetics, 2015 Sep 10; 7. PMID: 26351548    Free PMC article.
The omniscient placenta: Metabolic and epigenetic regulation of fetal programming.
Bridget M Nugent, Tracy L Bale.
Front Neuroendocrinol, 2015 Sep 15; 39. PMID: 26368654    Free PMC article.
Highly Cited. Review.
Assessing DNA methylation in the developing human intestinal epithelium: potential link to inflammatory bowel disease.
J Kraiczy, K Nayak, +7 authors, M Zilbauer.
Mucosal Immunol, 2015 Sep 17; 9(3). PMID: 26376367    Free PMC article.
The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans.
Robert Lowe, Marita G Overhoff, +6 authors, Cleo L Bishop.
Genome Biol, 2015 Sep 19; 16. PMID: 26381124    Free PMC article.
Tracing dynamic changes of DNA methylation at single-cell resolution.
Yonatan Stelzer, Chikdu Shakti Shivalila, +2 authors, Rudolf Jaenisch.
Cell, 2015 Sep 26; 163(1). PMID: 26406378    Free PMC article.
Aberrant 5'-CpG Methylation of Cord Blood TNFα Associated with Maternal Exposure to Polybrominated Diphenyl Ethers.
Tyna Dao, Xiumei Hong, Xiaobin Wang, Wan-Yee Tang.
PLoS One, 2015 Sep 26; 10(9). PMID: 26406892    Free PMC article.
Polycyclic aromatic hydrocarbon (PAH)-DNA adducts and breast cancer: modification by gene promoter methylation in a population-based study.
Alexandra J White, Jia Chen, +8 authors, Marilie D Gammon.
Cancer Causes Control, 2015 Sep 27; 26(12). PMID: 26407953    Free PMC article.
Epigenetic silencing of a long non-coding RNA KIAA0495 in multiple myeloma.
Kwan Yeung Wong, Zhenhai Li, +3 authors, Chor Sang Chim.
Mol Cancer, 2015 Sep 28; 14. PMID: 26410378    Free PMC article.
Epigenetic Alterations in Human Liver From Subjects With Type 2 Diabetes in Parallel With Reduced Folate Levels.
Emma Nilsson, Ashok Matte, +4 authors, Charlotte Ling.
J Clin Endocrinol Metab, 2015 Sep 30; 100(11). PMID: 26418287    Free PMC article.
Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome.
Da-Hai Yu, Manasi Gadkari, +18 authors, Lanlan Shen.
Genome Biol, 2015 Oct 01; 16. PMID: 26420038    Free PMC article.
MeSiC: A Model-Based Method for Estimating 5 mC Levels at Single-CpG Resolution from MeDIP-seq.
Yun Xiao, Fulong Yu, +9 authors, Xia Li.
Sci Rep, 2015 Oct 02; 5. PMID: 26424089    Free PMC article.
Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune Therapy.
Stuart J Gallagher, Jessamy C Tiffen, Peter Hersey.
Cancers (Basel), 2015 Oct 02; 7(4). PMID: 26426052    Free PMC article.
Review.
Enabling functional genomics with genome engineering.
Isaac B Hilton, Charles A Gersbach.
Genome Res, 2015 Oct 03; 25(10). PMID: 26430154    Free PMC article.
Review.
Estimating DNA methylation levels by joint modeling of multiple methylation profiles from microarray data.
Tao Wang, Mengjie Chen, Hongyu Zhao.
Biometrics, 2015 Oct 05; 72(2). PMID: 26433612    Free PMC article.
Length of paternal lifespan is manifested in the DNA methylome of their nonagenarian progeny.
Saara Marttila, Laura Kananen, +4 authors, Mikko Hurme.
Oncotarget, 2015 Oct 06; 6(31). PMID: 26436701    Free PMC article.
Low temperature-induced DNA hypermethylation attenuates expression of RhAG, an AGAMOUS homolog, and increases petal number in rose (Rosa hybrida).
Nan Ma, Wen Chen, +4 authors, Yonghong Li.
BMC Plant Biol, 2015 Oct 07; 15. PMID: 26438149    Free PMC article.
Adult porcine genome-wide DNA methylation patterns support pigs as a biomedical model.
Kyle M Schachtschneider, Ole Madsen, +3 authors, Lawrence B Schook.
BMC Genomics, 2015 Oct 07; 16. PMID: 26438392    Free PMC article.
Potential Gene Interactions in the Cell Cycles of Gametes, Zygotes, Embryonic Stem Cells and the Development of Cancer.
Gregor Prindull.
Front Oncol, 2015 Oct 07; 5. PMID: 26442212    Free PMC article.
Review.
Demystifying the secret mission of enhancers: linking distal regulatory elements to target genes.
Lijing Yao, Benjamin P Berman, Peggy J Farnham.
Crit Rev Biochem Mol Biol, 2015 Oct 09; 50(6). PMID: 26446758    Free PMC article.
Review.
Biomarkers of Nutrition for Development-Folate Review.
Lynn B Bailey, Patrick J Stover, +15 authors, Daniel J Raiten.
J Nutr, 2015 Oct 10; 145(7). PMID: 26451605    Free PMC article.
Highly Cited. Review.
Epigenetics and Cardiovascular Disease in Diabetes.
Jennifer Pasquier, Jessica Hoarau-Véchot, +2 authors, Charbel Abi Khalil.
Curr Diab Rep, 2015 Oct 16; 15(12). PMID: 26458379
Review.
Single-cell epigenomics: techniques and emerging applications.
Omer Schwartzman, Amos Tanay.
Nat Rev Genet, 2015 Oct 16; 16(12). PMID: 26460349
Highly Cited. Review.
Genome-wide DNA methylome reveals the dysfunction of intronic microRNAs in major psychosis.
Hongying Zhao, Jinyuan Xu, +10 authors, Yun Xiao.
BMC Med Genomics, 2015 Oct 16; 8. PMID: 26462620    Free PMC article.
DNA methylation Landscape of body size variation in sheep.
Jiaxue Cao, Caihong Wei, +15 authors, Lixin Du.
Sci Rep, 2015 Oct 17; 5. PMID: 26472088    Free PMC article.
Genome-wide DNA methylation detection by MethylCap-seq and Infinium HumanMethylation450 BeadChips: an independent large-scale comparison.
Tim De Meyer, Pierre Bady, +8 authors, Wim Van Criekinge.
Sci Rep, 2015 Oct 21; 5. PMID: 26482909    Free PMC article.
The transcriptional landscape of age in human peripheral blood.
Marjolein J Peters, Roby Joehanes, +113 authors, Andrew D Johnson.
Nat Commun, 2015 Oct 23; 6. PMID: 26490707    Free PMC article.
Highly Cited.
Hypermethylation of the GATA binding protein 4 (GATA4) promoter in Chinese pediatric acute myeloid leukemia.
Yan-Fang Tao, Fang Fang, +16 authors, Jian Pan.
BMC Cancer, 2015 Oct 23; 15. PMID: 26490736    Free PMC article.
DNA Methylation Landscapes of Human Fetal Development.
Roderick C Slieker, Matthias S Roost, +7 authors, Susana M Chuva de Sousa Lopes.
PLoS Genet, 2015 Oct 23; 11(10). PMID: 26492326    Free PMC article.
Epigenetic Histone Modifications Involved in Profibrotic Gene Regulation by 12/15-Lipoxygenase and Its Oxidized Lipid Products in Diabetic Nephropathy.
Hang Yuan, Marpadga A Reddy, +8 authors, Rama Natarajan.
Antioxid Redox Signal, 2015 Oct 24; 24(7). PMID: 26492974    Free PMC article.
Genome-wide DNA methylome variation in two genetically distinct chicken lines using MethylC-seq.
Jinxiu Li, Rujiao Li, +10 authors, Ning Li.
BMC Genomics, 2015 Oct 27; 16. PMID: 26497311    Free PMC article.
Influence of quasi-specific sites on kinetics of target DNA search by a sequence-specific DNA-binding protein.
Catherine A Kemme, Alexandre Esadze, Junji Iwahara.
Biochemistry, 2015 Oct 27; 54(44). PMID: 26502071    Free PMC article.
Polymorphisms involving gain or loss of CpG sites are significantly enriched in trait-associated SNPs.
Dan Zhou, Zhenli Li, +4 authors, Dandan Zhang.
Oncotarget, 2015 Oct 28; 6(37). PMID: 26503467    Free PMC article.
A novel method to analyze 5-hydroxymethylcytosine in CpG sequences using maintenance DNA methyltransferase, DNMT1.
Saori Takahashi, Isao Suetake, Jan Engelhardt, Shoji Tajima.
FEBS Open Bio, 2015 Oct 28; 5. PMID: 26504739    Free PMC article.
Characterization of DNA Methylation in Circulating Tumor Cells.
Constantin F Pixberg, Wolfgang A Schulz, Nikolas H Stoecklein, Rui P L Neves.
Genes (Basel), 2015 Oct 28; 6(4). PMID: 26506390    Free PMC article.
Review.
DNA N(6)-methyladenine: a new epigenetic mark in eukaryotes?
Guan-Zheng Luo, Mario Andres Blanco, +2 authors, Yang Shi.
Nat Rev Mol Cell Biol, 2015 Oct 29; 16(12). PMID: 26507168    Free PMC article.
Highly Cited. Review.
Resource base influences genome-wide DNA methylation levels in wild baboons (Papio cynocephalus).
Amanda J Lea, Jeanne Altmann, Susan C Alberts, Jenny Tung.
Mol Ecol, 2015 Oct 29; 25(8). PMID: 26508127    Free PMC article.
Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients.
Rubén Fernández-Santiago, Iria Carballo-Carbajal, +16 authors, Eduardo Tolosa.
EMBO Mol Med, 2015 Oct 31; 7(12). PMID: 26516212    Free PMC article.
Social Crowding during Development Causes Changes in GnRH1 DNA Methylation.
Sebastian G Alvarado, Kapa Lenkov, Blake Williams, Russell D Fernald.
PLoS One, 2015 Oct 31; 10(10). PMID: 26517121    Free PMC article.
JAM3 methylation status as a biomarker for diagnosis of preneoplastic and neoplastic lesions of the cervix.
Aijun Yin, Qing Zhang, +10 authors, Beihua Kong.
Oncotarget, 2015 Oct 31; 6(42). PMID: 26517242    Free PMC article.
Liver X Receptor Agonist Modifies the DNA Methylation Profile of Synapse and Neurogenesis-Related Genes in the Triple Transgenic Mouse Model of Alzheimer's Disease.
A G Sandoval-Hernández, H G Hernández, +7 authors, Gonzalo H Arboleda.
J Mol Neurosci, 2015 Nov 11; 58(2). PMID: 26553261
Combined exposure to protons and (56)Fe leads to overexpression of Il13 and reactivation of repetitive elements in the mouse lung.
Etienne Nzabarushimana, Sara Prior, +8 authors, Igor Koturbash.
Life Sci Space Res (Amst), 2015 Nov 11; 7. PMID: 26553631    Free PMC article.
In vivo epigenetic effects induced by engineered nanomaterials: A case study of copper oxide and laser printer-emitted engineered nanoparticles.
Xiaoyan Lu, Isabelle R Miousse, +4 authors, Philip Demokritou.
Nanotoxicology, 2015 Nov 13; 10(5). PMID: 26559097    Free PMC article.
Nanoparticle-mediated rhodopsin cDNA but not intron-containing DNA delivery causes transgene silencing in a rhodopsin knockout model.
Min Zheng, Rajendra N Mitra, Nazar A Filonov, Zongchao Han.
FASEB J, 2015 Nov 14; 30(3). PMID: 26564956    Free PMC article.
Relationships between PROMPT and gene expression.
Marta Lloret-Llinares, Christophe K Mapendano, +2 authors, Torben Heick Jensen.
RNA Biol, 2015 Nov 18; 13(1). PMID: 26574648    Free PMC article.
Dynamic changes in histone modifications precede de novo DNA methylation in oocytes.
Kathleen R Stewart, Lenka Veselovska, +6 authors, Gavin Kelsey.
Genes Dev, 2015 Nov 21; 29(23). PMID: 26584620    Free PMC article.
Highly Cited.
Stable recombination hotspots in birds.
Sonal Singhal, Ellen M Leffler, +10 authors, Molly Przeworski.
Science, 2015 Nov 21; 350(6263). PMID: 26586757    Free PMC article.
Highly Cited.
Patterns of gene expression and DNA methylation in human fetal and adult liver.
Susan M Huse, Philip A Gruppuso, Kim Boekelheide, Jennifer A Sanders.
BMC Genomics, 2015 Nov 22; 16. PMID: 26589361    Free PMC article.
Reading between the Lines: "ADD"-ing Histone and DNA Methylation Marks toward a New Epigenetic "Sum".
Kyung-Min Noh, C David Allis, Haitao Li.
ACS Chem Biol, 2015 Nov 26; 11(3). PMID: 26596909    Free PMC article.
Review.
Dnmt3a2: a hub for enhancing cognitive functions.
A M M Oliveira, T J Hemstedt, H E Freitag, H Bading.
Mol Psychiatry, 2015 Nov 26; 21(8). PMID: 26598069
A Flexible, Efficient Binomial Mixed Model for Identifying Differential DNA Methylation in Bisulfite Sequencing Data.
Amanda J Lea, Jenny Tung, Xiang Zhou.
PLoS Genet, 2015 Nov 26; 11(11). PMID: 26599596    Free PMC article.
Functional inhibition of mesenchymal stromal cells in acute myeloid leukemia.
S Geyh, M Rodríguez-Paredes, +12 authors, T Schroeder.
Leukemia, 2015 Nov 26; 30(3). PMID: 26601782
Short-Circuiting Gene Regulatory Networks: Origins of B Cell Lymphoma.
Olivia I Koues, Eugene M Oltz, Jacqueline E Payton.
Trends Genet, 2015 Nov 26; 31(12). PMID: 26604030    Free PMC article.
Review.
Genome-wide predictors of NF-κB recruitment and transcriptional activity.
Marcin Cieślik, Stefan Bekiranov.
BioData Min, 2015 Dec 01; 8. PMID: 26617673    Free PMC article.
Variations in the Intragene Methylation Profiles Hallmark Induced Pluripotency.
Pavel Druzhkov, Nikolay Zolotykh, +4 authors, Alexey Zaikin.
Biomed Res Int, 2015 Dec 01; 2015. PMID: 26618180    Free PMC article.
Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci.
Eilis Hannon, Helen Spiers, +9 authors, Jonathan Mill.
Nat Neurosci, 2015 Dec 01; 19(1). PMID: 26619357    Free PMC article.
Highly Cited.
Deoxyribonucleic acid (DNA) methyltransferase contributes to p16 promoter CpG island methylation in lung adenocarcinoma with smoking.
Rongju Sun, Jiahong Liu, +4 authors, Tanshi Li.
Int J Clin Exp Med, 2015 Dec 03; 8(9). PMID: 26629075    Free PMC article.
Unique Role for a DNA Methyltransferase Isoform in Lung Cancer.
Christopher E Duymich, Gangning Liang.
EBioMedicine, 2015 Dec 03; 2(10). PMID: 26629503    Free PMC article.
∆ DNMT3B4-del Contributes to Aberrant DNA Methylation Patterns in Lung Tumorigenesis.
Mark Z Ma, Ruxian Lin, +6 authors, Li Mao.
EBioMedicine, 2015 Dec 03; 2(10). PMID: 26629529    Free PMC article.
Intra-Gene DNA Methylation Variability Is a Clinically Independent Prognostic Marker in Women's Cancers.
Thomas E Bartlett, Allison Jones, +10 authors, Martin Widschwendter.
PLoS One, 2015 Dec 03; 10(12). PMID: 26629914    Free PMC article.
Diagnostic value of SHOX2 DNA methylation in lung cancer: a meta-analysis.
Qing-Tao Zhao, Tao Guo, +5 authors, Guo-Chen Duan.
Onco Targets Ther, 2015 Dec 08; 8. PMID: 26640383    Free PMC article.
In utero arsenic exposure and epigenome-wide associations in placenta, umbilical artery, and human umbilical vein endothelial cells.
Andres Cardenas, E Andres Houseman, +6 authors, Molly L Kile.
Epigenetics, 2015 Dec 10; 10(11). PMID: 26646901    Free PMC article.
DNA Methylation: Insights into Human Evolution.
Irene Hernando-Herraez, Raquel Garcia-Perez, Andrew J Sharp, Tomas Marques-Bonet.
PLoS Genet, 2015 Dec 15; 11(12). PMID: 26658498    Free PMC article.
Review.
Sera DNA Methylation of CDH1, DNMT3b and ESR1 Promoters as Biomarker for the Early Diagnosis of Hepatitis B Virus-Related Hepatocellular Carcinoma.
Cheng-Yun Dou, Yu-Chen Fan, +2 authors, Kai Wang.
Dig Dis Sci, 2015 Dec 15; 61(4). PMID: 26660680
Pediatric asthma and autism-genomic perspectives.
Sunghee Oh, Hong Ji, +2 authors, John Hutton.
Clin Transl Med, 2015 Dec 17; 4(1). PMID: 26668064    Free PMC article.
Sources of polycyclic aromatic hydrocarbons are associated with gene-specific promoter methylation in women with breast cancer.
Alexandra J White, Jia Chen, +16 authors, Marilie D Gammon.
Environ Res, 2015 Dec 17; 145. PMID: 26671626    Free PMC article.
Differential DNA Methylation Analysis without a Reference Genome.
Johanna Klughammer, Paul Datlinger, +5 authors, Christoph Bock.
Cell Rep, 2015 Dec 18; 13(11). PMID: 26673328    Free PMC article.
MethylAction: detecting differentially methylated regions that distinguish biological subtypes.
Jeffrey M Bhasin, Bo Hu, Angela H Ting.
Nucleic Acids Res, 2015 Dec 18; 44(1). PMID: 26673711    Free PMC article.
Epigenetic Biomarkers for the Early Detection of Gastrointestinal Cancer.
Hui-Mi Chen, Jing-Yua Fang.
Gastrointest Tumors, 2014 May 01; 1(4). PMID: 26674521    Free PMC article.
Review.
Competition between DNA methylation and transcription factors determines binding of NRF1.
Silvia Domcke, Anaïs Flore Bardet, +3 authors, Dirk Schübeler.
Nature, 2015 Dec 18; 528(7583). PMID: 26675734
Highly Cited.
Racial differences in genome-wide methylation profiling and gene expression in breast tissues from healthy women.
Min-Ae Song, Theodore M Brasky, +6 authors, Peter G Shields.
Epigenetics, 2015 Dec 19; 10(12). PMID: 26680018    Free PMC article.
Evolution and function of genomic imprinting in plants.
Jessica A Rodrigues, Daniel Zilberman.
Genes Dev, 2015 Dec 19; 29(24). PMID: 26680300    Free PMC article.
Review.
Detection of differentially methylated regions from bisulfite-seq data by hidden Markov models incorporating genome-wide methylation level distributions.
Yutaka Saito, Toutai Mituyama.
BMC Genomics, 2015 Dec 19; 16 Suppl 12. PMID: 26681544    Free PMC article.
Integrative genomic analysis reveals functional diversification of APOBEC gene family in breast cancer.
Yanfeng Zhang, Ryan Delahanty, +2 authors, Jirong Long.
Hum Genomics, 2015 Dec 20; 9. PMID: 26682542    Free PMC article.
Genome Wide Methylome Alterations in Lung Cancer.
Nandita Mullapudi, Bin Ye, +10 authors, Simon D Spivack.
PLoS One, 2015 Dec 20; 10(12). PMID: 26683690    Free PMC article.
The Yin and Yang of Chromatin Dynamics In Stem Cell Fate Selection.
Rene C Adam, Elaine Fuchs.
Trends Genet, 2015 Dec 23; 32(2). PMID: 26689127    Free PMC article.
Review.
Regulation of TIMP-1 in Human Placenta and Fetal Membranes by lipopolysaccharide and demethylating agent 5-aza-2'-deoxycytidine.
Zoë L Vincent, Murray D Mitchell, Anna P Ponnampalam.
Reprod Biol Endocrinol, 2015 Dec 23; 13. PMID: 26691525    Free PMC article.
Methylation analysis in fatty-acid-related genes reveals their plasticity associated with conjugated linoleic acid and calcium supplementation in adult mice.
Alice Chaplin, Andreu Palou, Francisca Serra.
Eur J Nutr, 2015 Dec 25; 56(2). PMID: 26700221
Evolutionary Transition of Promoter and Gene Body DNA Methylation across Invertebrate-Vertebrate Boundary.
Thomas E Keller, Priscilla Han, Soojin V Yi.
Mol Biol Evol, 2015 Dec 31; 33(4). PMID: 26715626    Free PMC article.
Making sense of GWAS: using epigenomics and genome engineering to understand the functional relevance of SNPs in non-coding regions of the human genome.
Yu Gyoung Tak, Peggy J Farnham.
Epigenetics Chromatin, 2016 Jan 01; 8. PMID: 26719772    Free PMC article.
Highly Cited. Review.
Association between SMN2 methylation and disease severity in Chinese children with spinal muscular atrophy.
Yan-yan Cao, Yu-jin Qu, +5 authors, Fang Song.
J Zhejiang Univ Sci B, 2016 Jan 08; 17(1). PMID: 26739529    Free PMC article.
A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity.
Lei Yuan, Gary C Chan, +14 authors, William C Aird.
Nat Commun, 2016 Jan 09; 7. PMID: 26744078    Free PMC article.
Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.
Linn Gillberg, Alexander Perfilyev, +11 authors, Charlotte Ling.
Diabetologia, 2016 Jan 12; 59(4). PMID: 26750116
Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation.
Lars Schomacher, Dandan Han, +4 authors, Christof Niehrs.
Nat Struct Mol Biol, 2016 Jan 12; 23(2). PMID: 26751644    Free PMC article.
Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity.
Christof Angermueller, Stephen J Clark, +10 authors, Wolf Reik.
Nat Methods, 2016 Jan 12; 13(3). PMID: 26752769    Free PMC article.
Highly Cited.
Identification of DNA Methylation-Independent Epigenetic Events Underlying Clear Cell Renal Cell Carcinoma.
Elinne Becket, Sameer Chopra, +9 authors, Gangning Liang.
Cancer Res, 2016 Jan 14; 76(7). PMID: 26759245    Free PMC article.
Expanding the diversity of DNA base modifications with N⁶-methyldeoxyadenosine.
Kate D Meyer, Samie R Jaffrey.
Genome Biol, 2016 Jan 15; 17. PMID: 26762117    Free PMC article.
Childbirth and consequent atopic disease: emerging evidence on epigenetic effects based on the hygiene and EPIIC hypotheses.
H G Dahlen, S Downe, +2 authors, J Y Taylor.
BMC Pregnancy Childbirth, 2016 Jan 15; 16. PMID: 26762406    Free PMC article.
DNA co-methylation modules in postmortem prefrontal cortex tissues of European Australians with alcohol use disorders.
Fan Wang, Hongqin Xu, +2 authors, Huiping Zhang.
Sci Rep, 2016 Jan 15; 6. PMID: 26763658    Free PMC article.
ADAM23 is downregulated in side population and suppresses lung metastasis of lung carcinoma cells.
Masahide Ota, Satsuki Mochizuki, +5 authors, Yasunori Okada.
Cancer Sci, 2016 Jan 23; 107(4). PMID: 26800504    Free PMC article.
Mechanisms underlying epigenetic and transcriptional heterogeneity in Chinese hamster ovary (CHO) cell lines.
Nathalie Veith, Holger Ziehr, Roderick A F MacLeod, Stella Marie Reamon-Buettner.
BMC Biotechnol, 2016 Jan 24; 16. PMID: 26800878    Free PMC article.
In silico analysis of regulatory and structural motifs of the ovine HSP90AA1 gene.
Carmen González, Judit Salces-Ortiz, Jorge H Calvo, M Magdalena Serrano.
Cell Stress Chaperones, 2016 Jan 27; 21(3). PMID: 26810179    Free PMC article.
Differential DNA methylation patterns of homeobox genes in proximal and distal colon epithelial cells.
Alan Barnicle, Cathal Seoighe, +2 authors, Laurence J Egan.
Physiol Genomics, 2016 Jan 28; 48(4). PMID: 26812987    Free PMC article.
Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer.
Holger Heyn, Enrique Vidal, +17 authors, Manel Esteller.
Genome Biol, 2016 Jan 28; 17. PMID: 26813288    Free PMC article.
Highly Cited.
Epigenetic regulation of hematopoiesis by DNA methylation.
Aniket V Gore, Brett Athans, +12 authors, Brant M Weinstein.
Elife, 2016 Jan 28; 5. PMID: 26814702    Free PMC article.
A Study of Alterations in DNA Epigenetic Modifications (5mC and 5hmC) and Gene Expression Influenced by Simulated Microgravity in Human Lymphoblastoid Cells.
Basudev Chowdhury, Arun Seetharam, +4 authors, Joseph Irudayaraj.
PLoS One, 2016 Jan 29; 11(1). PMID: 26820575    Free PMC article.
Prenatal Maternal Stress Predicts Methylation of Genes Regulating the Hypothalamic-Pituitary-Adrenocortical System in Mothers and Newborns in the Democratic Republic of Congo.
Darlene A Kertes, Hayley S Kamin, +3 authors, Connie J Mulligan.
Child Dev, 2016 Jan 30; 87(1). PMID: 26822443    Free PMC article.
Highly Cited.
The cardiovascular and hypothalamus-pituitary-adrenal axis response to stress is controlled by glucocorticoid receptor sequence variants and promoter methylation.
Ting Li-Tempel, Mauro F Larra, +5 authors, Jonathan D Turner.
Clin Epigenetics, 2016 Jan 30; 8. PMID: 26823689    Free PMC article.
Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes.
Symen Ligthart, Rebecca V Steenaard, +8 authors, Abbas Dehghan.
Diabetologia, 2016 Jan 31; 59(5). PMID: 26825526    Free PMC article.
DNA Methylation Indicates Susceptibility to Isoproterenol-Induced Cardiac Pathology and Is Associated With Chromatin States.
Haodong Chen, Luz D Orozco, +7 authors, Thomas M Vondriska.
Circ Res, 2016 Feb 04; 118(5). PMID: 26838786    Free PMC article.
Principles Governing DNA Methylation during Neuronal Lineage and Subtype Specification.
Ali Sharma, Shifra S Klein, +2 authors, Miklos Toth.
J Neurosci, 2016 Feb 05; 36(5). PMID: 26843651    Free PMC article.
Differential DNA methylation in peripheral blood mononuclear cells in adolescents exposed to significant early but not later childhood adversity.
Elisa A Esposito, Meaghan J Jones, +3 authors, Michael S Kobor.
Dev Psychopathol, 2016 Oct 26; 28(4pt2). PMID: 26847422    Free PMC article.
Sex-Dependent effects of developmental arsenic exposure on methylation capacity and methylation regulation of the glucocorticoid receptor system in the embryonic mouse brain.
Andrea M Allan, Alexander K Hafez, +4 authors, Abdulmehdi Ali.
Toxicol Rep, 2016 Feb 09; 2. PMID: 26855884    Free PMC article.
A genome-wide search for epigenetically [corrected] regulated genes in zebra finch using MethylCap-seq and RNA-seq.
Sandra Steyaert, Jolien Diddens, +9 authors, Tim De Meyer.
Sci Rep, 2016 Feb 13; 6. PMID: 26864856    Free PMC article.
Effects of aging on the male reproductive system.
Sezgin Gunes, Gulgez Neslihan Taskurt Hekim, Mehmet Alper Arslan, Ramazan Asci.
J Assist Reprod Genet, 2016 Feb 13; 33(4). PMID: 26867640    Free PMC article.
Systematic Review.
Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice.
Emily L Rossi, Rebecca E de Angel, +13 authors, Stephen D Hursting.
Cancer Prev Res (Phila), 2016 Feb 13; 9(5). PMID: 26869351    Free PMC article.
Strategies for Integrated Analysis of Genetic, Epigenetic, and Gene Expression Variation in Cancer: Addressing the Challenges.
Louise B Thingholm, Lars Andersen, +3 authors, Lise Lotte Hansen.
Front Genet, 2016 Feb 13; 7. PMID: 26870081    Free PMC article.
Review.
The Epigenomic Landscape of Prokaryotes.
Matthew J Blow, Tyson A Clark, +16 authors, Richard J Roberts.
PLoS Genet, 2016 Feb 13; 12(2). PMID: 26870957    Free PMC article.
Highly Cited.
A Feature Selection Algorithm to Compute Gene Centric Methylation from Probe Level Methylation Data.
Brittany Baur, Serdar Bozdag.
PLoS One, 2016 Feb 13; 11(2). PMID: 26872146    Free PMC article.
Increased DNA Methylation and Reduced Expression of Transcription Factors in Human Osteoarthritis Cartilage.
Oscar Alvarez-Garcia, Kathleen M Fisch, +5 authors, Martin K Lotz.
Arthritis Rheumatol, 2016 Feb 18; 68(8). PMID: 26881698    Free PMC article.
Iron and cancer: recent insights.
David H Manz, Nicole L Blanchette, +2 authors, Suzy V Torti.
Ann N Y Acad Sci, 2016 Feb 19; 1368(1). PMID: 26890363    Free PMC article.
Highly Cited. Review.
Enhancer methylation dynamics contribute to cancer plasticity and patient mortality.
Rachel E Bell, Tamar Golan, +8 authors, Carmit Levy.
Genome Res, 2016 Feb 26; 26(5). PMID: 26907635    Free PMC article.
Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation.
Aline C Planello, Rajat Singhania, +6 authors, Daniel D De Carvalho.
Oncotarget, 2016 Feb 26; 7(13). PMID: 26908456    Free PMC article.
MethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing.
Nicholas C Wong, Bernard J Pope, +9 authors, Alexander Dobrovic.
BMC Bioinformatics, 2016 Feb 26; 17. PMID: 26911705    Free PMC article.
Genome-wide DNA methylation profile of developing deciduous tooth germ in miniature pigs.
Yingying Su, Zhipeng Fan, +6 authors, Songlin Wang.
BMC Genomics, 2016 Feb 26; 17. PMID: 26911717    Free PMC article.
Profiling the genome-wide DNA methylation pattern of porcine ovaries using reduced representation bisulfite sequencing.
Xiao-Long Yuan, Ning Gao, +10 authors, Jia-Qi Li.
Sci Rep, 2016 Feb 26; 6. PMID: 26912189    Free PMC article.
Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats.
Chih-Chin Shih, Hiong-Ping Hii, +4 authors, Chin-Chen Wu.
PLoS One, 2016 Feb 27; 11(2). PMID: 26918767    Free PMC article.
Roles of Distal and Genic Methylation in the Development of Prostate Tumorigenesis Revealed by Genome-wide DNA Methylation Analysis.
Yao Wang, Rohit Ramakant Jadhav, +9 authors, Victor X Jin.
Sci Rep, 2016 Mar 01; 6. PMID: 26924343    Free PMC article.
Mechanisms of Disease of Eosinophilic Esophagitis.
Benjamin P Davis, Marc E Rothenberg.
Annu Rev Pathol, 2016 Mar 02; 11. PMID: 26925500    Free PMC article.
Review.
A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks.
Dinshaw J Patel.
Cold Spring Harb Perspect Biol, 2016 Mar 05; 8(3). PMID: 26931326    Free PMC article.
Review.
Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism.
Alain R Weber, Claudia Krawczyk, +5 authors, Primo Schär.
Nat Commun, 2016 Mar 05; 7. PMID: 26932196    Free PMC article.
Highly Cited.
Nucleic Acid Modifications in Regulation of Gene Expression.
Kai Chen, Boxuan Simen Zhao, Chuan He.
Cell Chem Biol, 2016 Mar 05; 23(1). PMID: 26933737    Free PMC article.
Highly Cited. Review.
Performance of Different Analytical Software Packages in Quantification of DNA Methylation by Pyrosequencing.
Chiara Grasso, Morena Trevisan, +6 authors, Anna Gillio-Tos.
PLoS One, 2016 Mar 05; 11(3). PMID: 26934703    Free PMC article.
Diagnostic and prognostic value of SHOX2 and SEPT9 DNA methylation and cytology in benign, paramalignant, and malignant ascites.
Maria Jung, Svenja Pützer, +3 authors, Dimo Dietrich.
Clin Epigenetics, 2016 Mar 05; 8. PMID: 26937257    Free PMC article.
The role of epigenetics in idiopathic male infertility.
Sezgin Gunes, Mehmet Alper Arslan, Gulgez Neslihan Taskurt Hekim, Ramazan Asci.
J Assist Reprod Genet, 2016 Mar 05; 33(5). PMID: 26941097    Free PMC article.
Review.
Potential Diagnostic and Prognostic Biomarkers of Epigenetic Drift within the Cardiovascular Compartment.
Robert G Wallace, Laura C Twomey, +4 authors, Ronan P Murphy.
Biomed Res Int, 2016 Mar 05; 2016. PMID: 26942189    Free PMC article.
Review.
Radiation-induced changes in DNA methylation of repetitive elements in the mouse heart.
Igor Koturbash, Isabelle R Miousse, +7 authors, Marjan Boerma.
Mutat Res, 2016 Mar 11; 787. PMID: 26963372    Free PMC article.
Epigenetic Mechanisms of the Aging Human Retina.
Katie L Pennington, Margaret M DeAngelis.
J Exp Neurosci, 2015 Jan 01; 9(Suppl 2). PMID: 26966390    Free PMC article.
Review.
Genome-wide analysis of DNA methylation and gene expression defines molecular characteristics of Crohn's disease-associated fibrosis.
Tammy Sadler, Jeffrey M Bhasin, +4 authors, Eleni Stylianou.
Clin Epigenetics, 2016 Mar 15; 8. PMID: 26973718    Free PMC article.
Epigenetic and Transcriptional Alterations in Human Adipose Tissue of Polycystic Ovary Syndrome.
Milana Kokosar, Anna Benrick, +8 authors, Elisabet Stener-Victorin.
Sci Rep, 2016 Mar 16; 6. PMID: 26975253    Free PMC article.
Effects of intratracheally instilled laser printer-emitted engineered nanoparticles in a mouse model: A case study of toxicological implications from nanomaterials released during consumer use.
Sandra V Pirela, Xiaoyan Lu, +8 authors, Philip Demokritou.
NanoImpact, 2016 Mar 19; 1. PMID: 26989787    Free PMC article.
Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues.
Gabriela Ecco, Marco Cassano, +7 authors, Didier Trono.
Dev Cell, 2016 Mar 24; 36(6). PMID: 27003935    Free PMC article.
Highly Cited.
Reduced DNA methylation patterning and transcriptional connectivity define human skin aging.
Felix Bormann, Manuel Rodríguez-Paredes, +10 authors, Frank Lyko.
Aging Cell, 2016 Mar 24; 15(3). PMID: 27004597    Free PMC article.
Epigenetic Regulatory Effect of Exercise on Glutathione Peroxidase 1 Expression in the Skeletal Muscle of Severely Dyslipidemic Mice.
Albert Nguyen, Natacha Duquette, Maya Mamarbachi, Eric Thorin.
PLoS One, 2016 Mar 25; 11(3). PMID: 27010651    Free PMC article.
Gene Body Methylation Patterns in Daphnia Are Associated with Gene Family Size.
Jana Asselman, Dieter I M De Coninck, Michael E Pfrender, Karel A C De Schamphelaere.
Genome Biol Evol, 2016 Mar 28; 8(4). PMID: 27017526    Free PMC article.
Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes.
Karl Bacos, Linn Gillberg, +12 authors, Charlotte Ling.
Nat Commun, 2016 Apr 01; 7. PMID: 27029739    Free PMC article.
Highly Cited.
DNA methylation as a potential mediator of environmental risks in the development of childhood acute lymphoblastic leukemia.
Jessica A Timms, Caroline L Relton, +2 authors, Jill A McKay.
Epigenomics, 2016 Apr 02; 8(4). PMID: 27035209    Free PMC article.
Review.
Effects of intracerebral hemorrhage on 5-hydroxymethylcytosine modification in mouse brains.
Yilin Tang, Sha Han, +5 authors, Liang Wang.
Neuropsychiatr Dis Treat, 2016 Apr 05; 12. PMID: 27042073    Free PMC article.
PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells.
Vashe Chandrakanthan, Avani Yeola, +29 authors, John E Pimanda.
Proc Natl Acad Sci U S A, 2016 Apr 05; 113(16). PMID: 27044077    Free PMC article.
MAOA gene hypomethylation in panic disorder-reversibility of an epigenetic risk pattern by psychotherapy.
C Ziegler, J Richter, +17 authors, K Domschke.
Transl Psychiatry, 2016 Apr 06; 6. PMID: 27045843    Free PMC article.
Immuno-regulated common markers but different network signatures in two associated cancers: evidences from epigenetic treatment.
Enrico Capobianco.
Ann Transl Med, 2016 Apr 06; 4(5). PMID: 27047945    Free PMC article.
Comprehensive analysis of genome-wide DNA methylation across human polycystic ovary syndrome ovary granulosa cell.
Jiawei Xu, Xiao Bao, +4 authors, Yingpu Sun.
Oncotarget, 2016 Apr 09; 7(19). PMID: 27056885    Free PMC article.
Preeclampsia/Eclampsia candidate genes show altered methylation in maternal leukocytes of preeclamptic women at the time of delivery.
Wendy M White, Zhifu Sun, +4 authors, Vesna D Garovic.
Hypertens Pregnancy, 2016 Apr 12; 35(3). PMID: 27064514    Free PMC article.
Epigenetic and genetic burden measures are associated with tumor characteristics in invasive breast carcinoma.
Dylan E O'Sullivan, Kevin C Johnson, +2 authors, Brock C Christensen.
Epigenetics, 2016 Apr 14; 11(5). PMID: 27070496    Free PMC article.
Association study between the DNMT3A -448A>G polymorphism and risk of Alzheimer's disease in Caucasians of Italian origin.
Pierpaola Tannorella, Andrea Stoccoro, +3 authors, Fabio Coppedè.
Am J Neurodegener Dis, 2016 Apr 14; 5(1). PMID: 27073746    Free PMC article.
Muscle cell identity requires Pax7-mediated lineage-specific DNA demethylation.
Elvira Carrió, Alessandro Magli, +3 authors, Mònica Suelves.
BMC Biol, 2016 Apr 15; 14. PMID: 27075038    Free PMC article.
Genome-wide DNA methylation analysis of transient neonatal diabetes type 1 patients with mutations in ZFP57.
Mads Bak, Susanne E Boonen, +7 authors, Niels Tommerup.
BMC Med Genet, 2016 Apr 15; 17. PMID: 27075368    Free PMC article.
Cloning and Characterization of a Human Genomic Sequence that Alleviates Repeat-Induced Gene Silencing.
Miki Fukuma, Yuto Ganmyo, +2 authors, Noriaki Shimizu.
PLoS One, 2016 Apr 15; 11(4). PMID: 27078685    Free PMC article.
Characterization of eukaryotic DNA N(6)-methyladenine by a highly sensitive restriction enzyme-assisted sequencing.
Guan-Zheng Luo, Fang Wang, +6 authors, Chuan He.
Nat Commun, 2016 Apr 16; 7. PMID: 27079427    Free PMC article.
HIC1 Expression Distinguishes Intestinal Carcinomas Sensitive to Chemotherapy.
Lucie Janeckova, Michal Kolar, +7 authors, Vladimir Korinek.
Transl Oncol, 2016 Apr 17; 9(2). PMID: 27084425    Free PMC article.
Protection of CpG islands from DNA methylation is DNA-encoded and evolutionarily conserved.
Hannah K Long, Hamish W King, +2 authors, Robert J Klose.
Nucleic Acids Res, 2016 Apr 17; 44(14). PMID: 27084945    Free PMC article.
Polymorphisms of the DNA Methyltransferase 1 Gene Predict Survival of Gastric Cancer Patients Receiving Tumorectomy.
Zhifang Jia, Xing Wu, +6 authors, Jing Jiang.
Dis Markers, 2016 Apr 19; 2016. PMID: 27087738    Free PMC article.
Isoform switching and exon skipping induced by the DNA methylation inhibitor 5-Aza-2'-deoxycytidine.
Xiao-Lei Ding, Xiaojing Yang, Gangning Liang, Kai Wang.
Sci Rep, 2016 Apr 20; 6. PMID: 27090213    Free PMC article.
Bisulfite oligonucleotide-capture sequencing for targeted base- and strand-specific absolute 5-methylcytosine quantitation.
Dustin R Masser, David R Stanford, +5 authors, Willard M Freeman.
Age (Dordr), 2016 Apr 20; 38(3). PMID: 27091453    Free PMC article.
Genome-wide profiles of methylation, microRNAs, and gene expression in chemoresistant breast cancer.
Dong-Xu He, Feng Gu, +7 authors, Xin Ma.
Sci Rep, 2016 Apr 21; 6. PMID: 27094684    Free PMC article.
Forensic DNA methylation profiling from evidence material for investigative leads.
Hwan Young Lee, Soong Deok Lee, Kyoung-Jin Shin.
BMB Rep, 2016 Apr 22; 49(7). PMID: 27099236    Free PMC article.
Review.
Circulating Differentially Methylated Amylin DNA as a Biomarker of β-Cell Loss in Type 1 Diabetes.
John A Olsen, Lauren A Kenna, +2 authors, Eitan M Akirav.
PLoS One, 2016 Apr 26; 11(4). PMID: 27111653    Free PMC article.
Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection.
Garima Sharma, Divya Tej Sowpati, +6 authors, Sanjeev Khosla.
Sci Rep, 2016 Apr 27; 6. PMID: 27112593    Free PMC article.
The concerted impact of domestication and transposon insertions on methylation patterns between dogs and grey wolves.
Ilana Janowitz Koch, Michelle M Clark, +12 authors, Bridgett M vonHoldt.
Mol Ecol, 2016 Apr 27; 25(8). PMID: 27112634    Free PMC article.
DNMT3B isoforms without catalytic activity stimulate gene body methylation as accessory proteins in somatic cells.
Christopher E Duymich, Jessica Charlet, +2 authors, Gangning Liang.
Nat Commun, 2016 Apr 29; 7. PMID: 27121154    Free PMC article.
Highly Cited.
Validation of differential GDAP1 DNA methylation in alcohol dependence and its potential function as a biomarker for disease severity and therapy outcome.
Christof Brückmann, Adriana Di Santo, +2 authors, Vanessa Nieratschker.
Epigenetics, 2016 Apr 30; 11(6). PMID: 27128683    Free PMC article.
Normal formation of a vertebrate body plan and loss of tissue maintenance in the absence of ezh2.
Bilge San, Naomi D Chrispijn, +6 authors, Leonie M Kamminga.
Sci Rep, 2016 May 06; 6. PMID: 27145952    Free PMC article.
Gene and transposable element methylation in great tit (Parus major) brain and blood.
Martijn F L Derks, Kyle M Schachtschneider, +3 authors, Kees van Oers.
BMC Genomics, 2016 May 06; 17. PMID: 27146629    Free PMC article.
The landscape of DNA methylation amid a perfect storm of autism aetiologies.
Annie Vogel Ciernia, Janine LaSalle.
Nat Rev Neurosci, 2016 May 07; 17(7). PMID: 27150399    Free PMC article.
Highly Cited. Review.
Bivalent Regions of Cytosine Methylation and H3K27 Acetylation Suggest an Active Role for DNA Methylation at Enhancers.
Jessica Charlet, Christopher E Duymich, +4 authors, Peter A Jones.
Mol Cell, 2016 May 08; 62(3). PMID: 27153539    Free PMC article.
Highly Cited.
OxyBS: estimation of 5-methylcytosine and 5-hydroxymethylcytosine from tandem-treated oxidative bisulfite and bisulfite DNA.
E Andres Houseman, Kevin C Johnson, Brock C Christensen.
Bioinformatics, 2016 May 07; 32(16). PMID: 27153596    Free PMC article.
Epigenomic profiling reveals an association between persistence of DNA methylation and metabolic memory in the DCCT/EDIC type 1 diabetes cohort.
Zhuo Chen, Feng Miao, +11 authors, Rama Natarajan.
Proc Natl Acad Sci U S A, 2016 May 11; 113(21). PMID: 27162351    Free PMC article.
Highly Cited.
Maternal Smoking during Pregnancy and DNA-Methylation in Children at Age 5.5 Years: Epigenome-Wide-Analysis in the European Childhood Obesity Project (CHOP)-Study.
Peter Rzehak, Richard Saffery, +13 authors, European Childhood Obesity Trial Study group.
PLoS One, 2016 May 14; 11(5). PMID: 27171005    Free PMC article.
Behavioural traits propagate across generations via segregated iterative-somatic and gametic epigenetic mechanisms.
Emma Mitchell, Shifra L Klein, +16 authors, Miklos Toth.
Nat Commun, 2016 May 14; 7. PMID: 27173585    Free PMC article.
H19ICR mediated transcriptional silencing does not require target promoter methylation.
Claudia Gebert, Qi Rong, +2 authors, Karl Pfeifer.
Biochem Biophys Res Commun, 2016 May 15; 476(3). PMID: 27178213    Free PMC article.
N (6)-Methyladenosine (m(6)A) Methylation in mRNA with A Dynamic and Reversible Epigenetic Modification.
Ruifan Wu, Denghu Jiang, Yizhen Wang, Xinxia Wang.
Mol Biotechnol, 2016 May 18; 58(7). PMID: 27179969
Review.
5-hydroxymethylcytosine marks regions with reduced mutation frequency in human DNA.
Marketa Tomkova, Michael McClellan, Skirmantas Kriaucionis, Benjamin Schuster-Boeckler.
Elife, 2016 May 18; 5. PMID: 27183007    Free PMC article.
AP endonuclease 1 prevents the extension of a T/G mismatch by DNA polymerase β to prevent mutations in CpGs during base excision repair.
Yanhao Lai, Zhongliang Jiang, +2 authors, Yuan Liu.
DNA Repair (Amst), 2016 May 18; 43. PMID: 27183823    Free PMC article.
The synergistic risk effect of apolipoprotein ε4 and DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B) haplotype for Alzheimer's disease.
Cíntia Monique Boschmann Ens de Bem, Julio Carlos Pezzi, +4 authors, Analuiza Camozzato.
Mol Biol Rep, 2016 May 18; 43(7). PMID: 27188425
Evolutionary Consequences of DNA Methylation in a Basal Metazoan.
Groves B Dixon, Line K Bay, Mikhail V Matz.
Mol Biol Evol, 2016 May 18; 33(9). PMID: 27189563    Free PMC article.
Epigenetic Determinants of Cancer.
Stephen B Baylin, Peter A Jones.
Cold Spring Harb Perspect Biol, 2016 May 20; 8(9). PMID: 27194046    Free PMC article.
Highly Cited. Review.
How to interpret epigenetic association studies: a guide for clinicians.
Javier Riancho, Alvaro Del Real, José A Riancho.
Bonekey Rep, 2016 May 20; 5. PMID: 27195108    Free PMC article.
Review.
Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity.
Katarzyna Lubecka, Lucinda Kurzava, +9 authors, Barbara Stefanska.
Carcinogenesis, 2016 May 22; 37(7). PMID: 27207652    Free PMC article.
Next-generation sequencing identifies major DNA methylation changes during progression of Ph+ chronic myeloid leukemia.
G Heller, T Topakian, +13 authors, S Zöchbauer-Müller.
Leukemia, 2016 May 24; 30(9). PMID: 27211271    Free PMC article.
Prostate cancer epigenetics and its clinical implications.
Srinivasan Yegnasubramanian.
Asian J Androl, 2016 May 24; 18(4). PMID: 27212125    Free PMC article.
Review.
Disagreement between two common biomarkers of global DNA methylation.
Claudia Knothe, Hiromi Shiratori, +4 authors, Jörn Lötsch.
Clin Epigenetics, 2016 May 26; 8. PMID: 27222668    Free PMC article.
Generating long-lived CD8(+) T-cell memory: Insights from epigenetic programs.
Pranay Dogra, Hazem E Ghoneim, Hossam A Abdelsamed, Ben Youngblood.
Eur J Immunol, 2016 May 28; 46(7). PMID: 27230488    Free PMC article.
Review.
Epigenetic Changes in Diabetes and Cardiovascular Risk.
Samuel T Keating, Jorge Plutzky, Assam El-Osta.
Circ Res, 2016 May 28; 118(11). PMID: 27230637    Free PMC article.
Review.
ITPKA Gene Body Methylation Regulates Gene Expression and Serves as an Early Diagnostic Marker in Lung and Other Cancers.
Yi-Wei Wang, Xiaotu Ma, +6 authors, Adi F Gazdar.
J Thorac Oncol, 2016 May 29; 11(9). PMID: 27234602    Free PMC article.
Guitar: An R/Bioconductor Package for Gene Annotation Guided Transcriptomic Analysis of RNA-Related Genomic Features.
Xiaodong Cui, Zhen Wei, +5 authors, Jia Meng.
Biomed Res Int, 2016 May 31; 2016. PMID: 27239475    Free PMC article.
Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity.
Xia Li, Qian Zhang, +11 authors, Xuetao Cao.
Nat Immunol, 2016 May 31; 17(7). PMID: 27240213
Highly Cited.
Aberrant DNA methylation of WNT pathway genes in the development and progression of CIMP-negative colorectal cancer.
Orsolya Galamb, Alexandra Kalmár, +12 authors, Béla Molnár.
Epigenetics, 2016 Jun 02; 11(8). PMID: 27245242    Free PMC article.
Epigenetic dysregulation in the developing Down syndrome cortex.
Nady El Hajj, Marcus Dittrich, +8 authors, Thomas Haaf.
Epigenetics, 2016 Jun 02; 11(8). PMID: 27245352    Free PMC article.
Comparison of genome-scale DNA methylation profiles in hepatocellular carcinoma by viral status.
Min-Ae Song, Sandi A Kwee, +5 authors, Herbert Yu.
Epigenetics, 2016 Jun 02; 11(6). PMID: 27248055    Free PMC article.
CRISPR/Cas9 therapeutics: a cure for cancer and other genetic diseases.
Faheem Ahmed Khan, Nuruliarizki Shinta Pandupuspitasari, +6 authors, Zhang ShuJun.
Oncotarget, 2016 Jun 03; 7(32). PMID: 27250031    Free PMC article.
Review.
Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells.
Xavier Tekpli, Alfonso Urbanucci, +8 authors, Judith Staerk.
Epigenetics Chromatin, 2016 Jun 03; 9. PMID: 27252783    Free PMC article.
DNA Methylation Signature Reveals Cell Ontogeny of Renal Cell Carcinomas.
Gabriel G Malouf, Xiaoping Su, +13 authors, Nizar M Tannir.
Clin Cancer Res, 2016 Jun 04; 22(24). PMID: 27256309    Free PMC article.
Luminal STAT5 mediates H2AX promoter activity in distinct population of basal mammary epithelial cells.
Moshe Reichenstein, Gat Rauner, +2 authors, Itamar Barash.
Oncotarget, 2016 Jun 05; 7(27). PMID: 27260000    Free PMC article.
Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer.
Michael S Lee, Elizabeth J McGuffey, +9 authors, Scott Kopetz.
Br J Cancer, 2016 Jun 09; 114(12). PMID: 27272216    Free PMC article.
Genome-wide redistribution of MeCP2 in dorsal root ganglia after peripheral nerve injury.
Melissa T Manners, Adam Ertel, Yuzhen Tian, Seena K Ajit.
Epigenetics Chromatin, 2016 Jun 10; 9. PMID: 27279901    Free PMC article.
Peripheral blood methylation profiling of female Crohn's disease patients.
Andrew Y F Li Yim, Nicolette W Duijvis, +6 authors, Peter Henneman.
Clin Epigenetics, 2016 Jun 10; 8. PMID: 27279921    Free PMC article.
A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.
Petr Volkov, Anders H Olsson, +9 authors, Charlotte Ling.
PLoS One, 2016 Jun 21; 11(6). PMID: 27322064    Free PMC article.
MethylMeter(®): bisulfite-free quantitative and sensitive DNA methylation profiling and mutation detection in FFPE samples.
David McCarthy, Walter Pulverer, +4 authors, Michelle M Hanna.
Epigenomics, 2016 Jun 24; 8(6). PMID: 27337298    Free PMC article.
Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development.
Rui Lu, Ping Wang, +8 authors, Gang Greg Wang.
Cancer Cell, 2016 Jun 28; 30(1). PMID: 27344947    Free PMC article.
Highly Cited.
Information recovery from low coverage whole-genome bisulfite sequencing.
Emanuele Libertini, Simon C Heath, +10 authors, Stephan Beck.
Nat Commun, 2016 Jun 28; 7. PMID: 27346250    Free PMC article.
From GWAS to function: lessons from blood cells.
L J Vasquez, A L Mann, L Chen, N Soranzo.
ISBT Sci Ser, 2016 Jun 28; 11(Suppl 1). PMID: 27347004    Free PMC article.
CRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter.
Samrat Roy Choudhury, Yi Cui, +2 authors, Joseph Irudayaraj.
Oncotarget, 2016 Jul 01; 7(29). PMID: 27356740    Free PMC article.
Highly Cited.
DNA methylation signature of human fetal alcohol spectrum disorder.
Elodie Portales-Casamar, Alexandre A Lussier, +12 authors, Michael S Kobor.
Epigenetics Chromatin, 2016 Jul 01; 9. PMID: 27358653    Free PMC article.
Highly Cited.
Profiling genome-wide DNA methylation.
Wai-Shin Yong, Fei-Man Hsu, Pao-Yang Chen.
Epigenetics Chromatin, 2016 Jul 01; 9. PMID: 27358654    Free PMC article.
Highly Cited. Review.
Changes in CpG methylation marks differentiation of human myeloid progenitors to neutrophils.
Justin J L Wong, Jeff Holst.
Stem Cell Investig, 2014 Jan 01; 1. PMID: 27358856    Free PMC article.
Prenatal exposures and DNA methylation in newborns: a pilot study in Durban, South Africa.
Jaclyn M Goodrich, Poovendhree Reddy, +3 authors, Dana C Dolinoy.
Environ Sci Process Impacts, 2016 Jul 01; 18(7). PMID: 27359112    Free PMC article.
Regulation of the DNA Methylation Landscape in Human Somatic Cell Reprogramming by the miR-29 Family.
Eriona Hysolli, Yoshiaki Tanaka, +13 authors, In-Hyun Park.
Stem Cell Reports, 2016 Jul 05; 7(1). PMID: 27373925    Free PMC article.
A Minimally-invasive Blood-derived Biomarker of Oligodendrocyte Cell-loss in Multiple Sclerosis.
John A Olsen, Lauren A Kenna, +3 authors, Eitan M Akirav.
EBioMedicine, 2016 Jul 07; 10. PMID: 27381476    Free PMC article.
Optogenetic regulation of site-specific subtelomeric DNA methylation.
Samrat Roy Choudhury, Yi Cui, +6 authors, Joseph Irudayaraj.
Oncotarget, 2016 Jul 09; 7(31). PMID: 27391261    Free PMC article.
Induction of HOXA9 expression in three-dimensional organotypic culture of the Claudin-low breast cancer cells.
Miao Li, Xi Li, +6 authors, Bin Shan.
Oncotarget, 2016 Jul 14; 7(32). PMID: 27409175    Free PMC article.
Densely ionizing radiation affects DNA methylation of selective LINE-1 elements.
Sara Prior, Isabelle R Miousse, +9 authors, Igor Koturbash.
Environ Res, 2016 Jul 16; 150. PMID: 27419368    Free PMC article.
Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation.
Francine E Garrett-Bakelman, Ari M Melnick.
Epigenomics, 2016 Jul 20; 8(7). PMID: 27431380    Free PMC article.
Review.
Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas.
Annette M Lim, Nicholas C Wong, +6 authors, Benjamin Solomon.
Clin Epigenetics, 2016 Jul 20; 8. PMID: 27433284    Free PMC article.
DNA Methylation Variation Trends during the Embryonic Development of Chicken.
Shizhao Li, Yufei Zhu, +5 authors, Xiaojun Yang.
PLoS One, 2016 Jul 22; 11(7). PMID: 27438711    Free PMC article.
Preliminary assessment of pre-morbid DNA methylation in individuals at high genetic risk of mood disorders.
Rosie May Walker, Jessika Elizabeth Sussmann, +4 authors, Kathryn Louise Evans.
Bipolar Disord, 2016 Jul 22; 18(5). PMID: 27440233    Free PMC article.
Dynamic DNA methylation of matrix metalloproteinase-9 in the development of diabetic retinopathy.
Renu A Kowluru, Yang Shan, Manish Mishra.
Lab Invest, 2016 Jul 28; 96(10). PMID: 27454437    Free PMC article.
Negative regulation of DNMT3A de novo DNA methylation by frequently overexpressed UHRF family proteins as a mechanism for widespread DNA hypomethylation in cancer.
Yuanhui Jia, Pishun Li, +17 authors, Jiemin Wong.
Cell Discov, 2016 Jul 28; 2. PMID: 27462454    Free PMC article.
Integrative epigenomic analysis reveals unique epigenetic signatures involved in unipotency of mouse female germline stem cells.
Xiao-Li Zhang, Jun Wu, +10 authors, Xiaodong Zhao.
Genome Biol, 2016 Jul 29; 17(1). PMID: 27465593    Free PMC article.
High-efficiency generation of induced pluripotent mesenchymal stem cells from human dermal fibroblasts using recombinant proteins.
Fanfan Chen, Guoqiang Zhang, +6 authors, Sriharsa Pradhan.
Stem Cell Res Ther, 2016 Jul 31; 7(1). PMID: 27473118    Free PMC article.
DISMISS: detection of stranded methylation in MeDIP-Seq data.
Umar Niazi, Kathrin K Geyer, +2 authors, Martin T Swain.
BMC Bioinformatics, 2016 Jul 31; 17(1). PMID: 27473283    Free PMC article.
Differentiation stage of myeloma plasma cells: biological and clinical significance.
B Paiva, N Puig, +28 authors, J F San-Miguel.
Leukemia, 2016 Aug 02; 31(2). PMID: 27479184    Free PMC article.
Are there specific readers of oxidized 5-methylcytosine bases?
Jikui Song, Gerd P Pfeifer.
Bioessays, 2016 Aug 03; 38(10). PMID: 27480808    Free PMC article.
Review.
Molecular and epigenetic features of melanomas and tumor immune microenvironment linked to durable remission to ipilimumab-based immunotherapy in metastatic patients.
Teofila Seremet, Alexander Koch, +12 authors, Bart Neyns.
J Transl Med, 2016 Aug 04; 14(1). PMID: 27484791    Free PMC article.
Genome-wide measures of DNA methylation in peripheral blood and the risk of urothelial cell carcinoma: a prospective nested case-control study.
Pierre-Antoine Dugué, Maree T Brinkman, +19 authors, Graham G Giles.
Br J Cancer, 2016 Aug 05; 115(6). PMID: 27490804    Free PMC article.
Epigenetic and microRNA regulation during osteoarthritis development.
Di Chen, Jie Shen, Tianqian Hui.
F1000Res, 2015 Jan 01; 4. PMID: 27508054    Free PMC article.
Review.
Human Papillomavirus Type 16 L2 DNA Methylation in Exfoliated Cervical Cells From College-Age Women.
Erin L Anderson, Carolyn E Banister, +4 authors, Michael D Wyatt.
J Low Genit Tract Dis, 2016 Aug 16; 20(4). PMID: 27518844    Free PMC article.
Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm.
Albert Jeltsch, Renata Z Jurkowska.
Nucleic Acids Res, 2016 Aug 16; 44(18). PMID: 27521372    Free PMC article.
Review.
Human effector B lymphocytes express ARID3a and secrete interferon alpha.
Julie M Ward, Michelle L Ratliff, +5 authors, Carol F Webb.
J Autoimmun, 2016 Aug 16; 75. PMID: 27522115    Free PMC article.
Aberrant Endometrial DNA Methylome and Associated Gene Expression in Women with Endometriosis.
Sahar Houshdaran, Camran R Nezhat, +3 authors, Linda C Giudice.
Biol Reprod, 2016 Nov 05; 95(5). PMID: 27535958    Free PMC article.
Erasure and reestablishment of random allelic expression imbalance after epigenetic reprogramming.
Aaron Richard Jeffries, Dafe Aghogho Uwanogho, +4 authors, Jack Price.
RNA, 2016 Aug 20; 22(10). PMID: 27539784    Free PMC article.
Dissecting the precise role of H3K9 methylation in crosstalk with DNA maintenance methylation in mammals.
Qian Zhao, Jiqin Zhang, +13 authors, Jiemin Wong.
Nat Commun, 2016 Aug 25; 7. PMID: 27554592    Free PMC article.
Dynamic DNA methylation regulates neuronal intrinsic membrane excitability.
Jarrod P Meadows, Mikael C Guzman-Karlsson, +4 authors, John J Hablitz.
Sci Signal, 2016 Aug 25; 9(442). PMID: 27555660    Free PMC article.
YTHDF2 destabilizes m(6)A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex.
Hao Du, Ya Zhao, +5 authors, Ligang Wu.
Nat Commun, 2016 Aug 26; 7. PMID: 27558897    Free PMC article.
Highly Cited.
Epigenetic Regulation of Caveolin-1 Gene Expression in Lung Fibroblasts.
Yan Y Sanders, Hui Liu, +3 authors, Victor J Thannickal.
Am J Respir Cell Mol Biol, 2016 Aug 26; 56(1). PMID: 27560128    Free PMC article.
Genome-wide landscape of DNA methylomes and their relationship with mRNA and miRNA transcriptomes in oxidative and glycolytic skeletal muscles.
Linyuan Shen, Jingjing Du, +10 authors, Li Zhu.
Sci Rep, 2016 Aug 27; 6. PMID: 27561200    Free PMC article.
DNA methylation profiling in human lung tissue identifies genes associated with COPD.
Jarrett D Morrow, Michael H Cho, +11 authors, Dawn L DeMeo.
Epigenetics, 2016 Aug 27; 11(10). PMID: 27564456    Free PMC article.
Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function.
Andrew J Kennedy, Elizabeth J Rahn, +15 authors, J David Sweatt.
Cell Rep, 2016 Aug 30; 16(10). PMID: 27568567    Free PMC article.
Epigenetic regulation of OAS2 shows disease-specific DNA methylation profiles at individual CpG sites.
Xiaolian Gu, Linda Boldrup, +7 authors, Karin Nylander.
Sci Rep, 2016 Aug 31; 6. PMID: 27572959    Free PMC article.
Mammalian non-CG methylations are conserved and cell-type specific and may have been involved in the evolution of transposon elements.
Weilong Guo, Michael Q Zhang, Hong Wu.
Sci Rep, 2016 Aug 31; 6. PMID: 27573482    Free PMC article.
The epigenome in Alzheimer's disease: current state and approaches for a new path to gene discovery and understanding disease mechanism.
Hans-Ulrich Klein, David A Bennett, Philip L De Jager.
Acta Neuropathol, 2016 Aug 31; 132(4). PMID: 27573688    Free PMC article.
Review.
The epigenome: the next substrate for engineering.
Minhee Park, Albert J Keung, Ahmad S Khalil.
Genome Biol, 2016 Sep 02; 17(1). PMID: 27582168    Free PMC article.
Review.
Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study.
Elisabetta Valentini, Michele Zampieri, +21 authors, Paola Caiafa.
Aging (Albany NY), 2016 Sep 03; 8(9). PMID: 27587280    Free PMC article.
DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistance.
Ailsa Maria Main, Linn Gillberg, +6 authors, Allan Vaag.
Clin Epigenetics, 2016 Sep 07; 8. PMID: 27594926    Free PMC article.
DNA methylation: conducting the orchestra from exposure to phenotype?
Fleur A D Leenen, Claude P Muller, Jonathan D Turner.
Clin Epigenetics, 2016 Sep 08; 8. PMID: 27602172    Free PMC article.
Highly Cited. Review.
Aberrant methylation of cell-free circulating DNA in plasma predicts poor outcome in diffuse large B cell lymphoma.
Lasse Sommer Kristensen, Jakob Werner Hansen, +5 authors, Kirsten Grønbæk.
Clin Epigenetics, 2016 Sep 10; 8(1). PMID: 27610206    Free PMC article.
Secondhand Tobacco Smoke Exposure Associations With DNA Methylation of the Aryl Hydrocarbon Receptor Repressor.
Lindsay M Reynolds, Hoda S Magid, +7 authors, Yongmei Liu.
Nicotine Tob Res, 2016 Sep 11; 19(4). PMID: 27613907    Free PMC article.
Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment.
Michael J Corley, Christian Dye, +9 authors, Alika K Maunakea.
Sci Rep, 2016 Sep 16; 6. PMID: 27629381    Free PMC article.
Targeting the cancer epigenome for therapy.
Peter A Jones, Jean-Pierre J Issa, Stephen Baylin.
Nat Rev Genet, 2016 Sep 16; 17(10). PMID: 27629931
Highly Cited. Review.
Methylation and mRNA expression levels of P15, death-associated protein kinase, and suppressor of cytokine signaling-1 genes in multiple myeloma.
Lin Liu, Lin Tan, Zhenxin He.
Iran J Basic Med Sci, 2016 Sep 17; 19(7). PMID: 27635200    Free PMC article.
Evaluation of DNMT1 gene expression profile and methylation of its promoter region in patients with ankylosing spondylitis.
Saeed Aslani, Mahdi Mahmoudi, +3 authors, Mohammad Hossein Nicknam.
Clin Rheumatol, 2016 Sep 18; 35(11). PMID: 27637577
AMPK/α-Ketoglutarate Axis Dynamically Mediates DNA Demethylation in the Prdm16 Promoter and Brown Adipogenesis.
Qiyuan Yang, Xingwei Liang, +13 authors, Min Du.
Cell Metab, 2016 Sep 20; 24(4). PMID: 27641099    Free PMC article.
Highly Cited.
Epigenetic markers to further understand insulin resistance.
Charlotte Ling, Tina Rönn.
Diabetologia, 2016 Sep 22; 59(11). PMID: 27650286
Reprogramming of mPFC transcriptome and function in alcohol dependence.
M Heilig, E Barbier, +5 authors, W H Sommer.
Genes Brain Behav, 2016 Sep 23; 16(1). PMID: 27657733    Free PMC article.
Review.
Establishment and functions of DNA methylation in the germline.
Kathleen R Stewart, Lenka Veselovska, Gavin Kelsey.
Epigenomics, 2016 Sep 24; 8(10). PMID: 27659720    Free PMC article.
Review.
Procainamide Inhibits DNA Methylation and Alleviates Multiple Organ Dysfunction in Rats with Endotoxic Shock.
Chih-Chin Shih, Mei-Hui Liao, +6 authors, Chin-Chen Wu.
PLoS One, 2016 Sep 24; 11(9). PMID: 27661616    Free PMC article.
CpG site DNA methylation patterns reveal a novel regulatory element in the mouse prion protein gene.
Wuyun Dalai, Eiko Matsuo, +2 authors, Keiichi Saeki.
J Vet Med Sci, 2016 Sep 27; 79(1). PMID: 27666463    Free PMC article.
Widespread natural variation of DNA methylation within angiosperms.
Chad E Niederhuth, Adam J Bewick, +13 authors, Robert J Schmitz.
Genome Biol, 2016 Sep 28; 17(1). PMID: 27671052    Free PMC article.
Highly Cited.
Identification of DNA methylation changes associated with disease progression in subchondral bone with site-matched cartilage in knee osteoarthritis.
Yanfei Zhang, Naoshi Fukui, +4 authors, Ming Ta Michael Lee.
Sci Rep, 2016 Oct 01; 6. PMID: 27686527    Free PMC article.
DNA Methylation Heterogeneity Patterns in Breast Cancer Cell Lines.
Sunny Tian, Karina Bertelsmann, Linda Yu, Shuying Sun.
Cancer Inform, 2016 Oct 01; 15(Supple 4). PMID: 27688708    Free PMC article.
Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis.
Yen Ching Lim, Sook Yoong Chia, +3 authors, Lei Sun.
Mol Metab, 2016 Oct 01; 5(10). PMID: 27689016    Free PMC article.
Possible role of intragenic DNA hypermethylation in gene silencing of the tumor suppressor gene NR4A3 in acute myeloid leukemia.
Ryo Shimizu, Tomoya Muto, +19 authors, Chiaki Nakaseko.
Leuk Res, 2016 Oct 27; 50. PMID: 27697661    Free PMC article.
PITX3 promoter methylation is a prognostic biomarker for biochemical recurrence-free survival in prostate cancer patients after radical prostatectomy.
Emily Eva Holmes, Diane Goltz, +8 authors, Dimo Dietrich.
Clin Epigenetics, 2016 Oct 07; 8. PMID: 27708722    Free PMC article.
DNA Methylation Patterns in Rat Mammary Carcinomas Induced by Pre- and Post-Pubertal Irradiation.
Masaru Takabatake, Benjamin J Blyth, +4 authors, Yoshiya Shimada.
PLoS One, 2016 Oct 07; 11(10). PMID: 27711132    Free PMC article.
A pre-neoplastic epigenetic field defect in HCV-infected liver at transcription factor binding sites and polycomb targets.
N A Wijetunga, M Pascual, +6 authors, J M Greally.
Oncogene, 2016 Oct 11; 36(14). PMID: 27721404    Free PMC article.
Whole-genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver.
Xin Li, Yun Liu, +2 authors, Andrew Feinberg.
Genome Res, 2016 Oct 16; 26(12). PMID: 27737935    Free PMC article.
The nasal methylome and childhood atopic asthma.
Ivana V Yang, Brent S Pedersen, +21 authors, David A Schwartz.
J Allergy Clin Immunol, 2016 Oct 18; 139(5). PMID: 27745942    Free PMC article.
Epigenetics in Schizophrenia: A Pilot Study of Global DNA Methylation in Different Brain Regions Associated with Higher Cognitive Functions.
Raúl Alelú-Paz, Francisco J Carmona, +10 authors, Santiago Ropero.
Front Psychol, 2016 Oct 18; 7. PMID: 27746755    Free PMC article.
Gene regulation and genetics in neurochemistry, past to future.
Steven W Barger.
J Neurochem, 2016 Nov 01; 139 Suppl 2. PMID: 27747882    Free PMC article.
Review.
Dnmt3b Methylates DNA by a Noncooperative Mechanism, and Its Activity Is Unaffected by Manipulations at the Predicted Dimer Interface.
Allison B Norvil, Christopher J Petell, +3 authors, Humaira Gowher.
Biochemistry, 2016 Oct 22; 57(29). PMID: 27768276    Free PMC article.
Air pollution, epigenetics, and asthma.
Hong Ji, Jocelyn M Biagini Myers, +3 authors, Gurjit K Khurana Hershey.
Allergy Asthma Clin Immunol, 2016 Oct 26; 12. PMID: 27777592    Free PMC article.
Review.
Epigenetic Modifications, Alcoholic Brain and Potential Drug Targets.
Ashok Jangra, Chandra Shaker Sriram, +5 authors, Mangala Lahkar.
Ann Neurosci, 2016 Oct 27; 23(4). PMID: 27780992    Free PMC article.
Review.
Genome-wide methylation analysis identified sexually dimorphic methylated regions in hybrid tilapia.
Zi Yi Wan, Jun Hong Xia, +3 authors, Gen Hua Yue.
Sci Rep, 2016 Oct 27; 6. PMID: 27782217    Free PMC article.
The Role of DNA Methylation in the Metabolic Memory Phenomenon Associated With the Continued Progression of Diabetic Retinopathy.
Manish Mishra, Renu A Kowluru.
Invest Ophthalmol Vis Sci, 2016 Oct 28; 57(13). PMID: 27787562    Free PMC article.
Causal role of histone acetylations in enhancer function.
Madapura M Pradeepa.
Transcription, 2016 Oct 30; 8(1). PMID: 27792455    Free PMC article.
DNA demethylation induces SALL4 gene re-expression in subgroups of hepatocellular carcinoma associated with Hepatitis B or C virus infection.
H Fan, Z Cui, +6 authors, O Andrisani.
Oncogene, 2016 Nov 01; 36(17). PMID: 27797380    Free PMC article.
omicsNPC: Applying the Non-Parametric Combination Methodology to the Integrative Analysis of Heterogeneous Omics Data.
Nestoras Karathanasis, Ioannis Tsamardinos, Vincenzo Lagani.
PLoS One, 2016 Nov 05; 11(11). PMID: 27812137    Free PMC article.
Adolescent binge-pattern alcohol exposure alters genome-wide DNA methylation patterns in the hypothalamus of alcohol-naïve male offspring.
AnnaDorothea Asimes, Audrey Torcaso, +3 authors, Toni R Pak.
Alcohol, 2016 Nov 08; 60. PMID: 27817987    Free PMC article.
Cell-Intrinsic Barriers of T Cell-Based Immunotherapy.
Hazem E Ghoneim, Anthony E Zamora, Paul G Thomas, Ben A Youngblood.
Trends Mol Med, 2016 Nov 09; 22(12). PMID: 27825667    Free PMC article.
Review.
Methylation analyses in liquid biopsy.
Delphine Lissa, Ana I Robles.
Transl Lung Cancer Res, 2016 Nov 09; 5(5). PMID: 27826530    Free PMC article.
Review.
N6-Methyladenine: A Conserved and Dynamic DNA Mark.
Zach Klapholz O'Brown, Eric Lieberman Greer.
Adv Exp Med Biol, 2016 Nov 09; 945. PMID: 27826841    Free PMC article.
Review.
Regulatory landscape and clinical implication of MBD3 in human malignant glioma.
Yi Cui, Jian Li, +6 authors, Joseph Irudayaraj.
Oncotarget, 2016 Nov 12; 7(49). PMID: 27835581    Free PMC article.
PD-L1 promoter methylation is a prognostic biomarker for biochemical recurrence-free survival in prostate cancer patients following radical prostatectomy.
Heidrun Gevensleben, Emily Eva Holmes, +5 authors, Glen Kristiansen.
Oncotarget, 2016 Nov 12; 7(48). PMID: 27835597    Free PMC article.
Meta-analysis of DNA methylation biomarkers in hepatocellular carcinoma.
Cheng Zhang, Jinyun Li, +10 authors, Kaifeng Wang.
Oncotarget, 2016 Nov 12; 7(49). PMID: 27835605    Free PMC article.
Review.
A Statistical Framework to Identify Deviation from Time Linearity in Epigenetic Aging.
Sagi Snir, Bridgett M vonHoldt, Matteo Pellegrini.
PLoS Comput Biol, 2016 Nov 12; 12(11). PMID: 27835646    Free PMC article.
Understanding epigenetic architecture of suicide neurobiology: A critical perspective.
Bhaskar Roy, Yogesh Dwivedi.
Neurosci Biobehav Rev, 2016 Nov 12; 72. PMID: 27836463    Free PMC article.
Review.
SHOX2 is a Potent Independent Biomarker to Predict Survival of WHO Grade II-III Diffuse Gliomas.
Yu-An Zhang, Yunyun Zhou, +6 authors, Adi F Gazdar.
EBioMedicine, 2016 Nov 15; 13. PMID: 27840009    Free PMC article.
Transcription factor LSF-DNMT1 complex dissociation by FQI1 leads to aberrant DNA methylation and gene expression.
Hang Gyeong Chin, V K Chaithanya Ponnaluri, +4 authors, Sriharsa Pradhan.
Oncotarget, 2016 Nov 16; 7(50). PMID: 27845898    Free PMC article.
Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage.
Ana C Queirós, Renée Beekman, +32 authors, José I Martín-Subero.
Cancer Cell, 2016 Nov 16; 30(5). PMID: 27846393    Free PMC article.
The caste- and sex-specific DNA methylome of the termite Zootermopsis nevadensis.
Karl M Glastad, Kaustubh Gokhale, Jürgen Liebig, Michael A D Goodisman.
Sci Rep, 2016 Nov 17; 6. PMID: 27848993    Free PMC article.
The genome of the crustacean Parhyale hawaiensis, a model for animal development, regeneration, immunity and lignocellulose digestion.
Damian Kao, Alvina G Lai, +21 authors, Aziz Aboobaker.
Elife, 2016 Nov 17; 5. PMID: 27849518    Free PMC article.
Highly Cited.
Promoter methylation of the immune checkpoint receptor PD-1 (PDCD1) is an independent prognostic biomarker for biochemical recurrence-free survival in prostate cancer patients following radical prostatectomy.
Diane Goltz, Heidrun Gevensleben, +4 authors, Dimo Dietrich.
Oncoimmunology, 2016 Nov 18; 5(10). PMID: 27853645    Free PMC article.
Genome-wide DNA methylation analysis identifies MEGF10 as a novel epigenetically repressed candidate tumor suppressor gene in neuroblastoma.
Jessica Charlet, Ayumi Tomari, +8 authors, Keith W Brown.
Mol Carcinog, 2016 Nov 20; 56(4). PMID: 27862318    Free PMC article.
Ever-Changing Landscapes: Transcriptional Enhancers in Development and Evolution.
Hannah K Long, Sara L Prescott, Joanna Wysocka.
Cell, 2016 Nov 20; 167(5). PMID: 27863239    Free PMC article.
Highly Cited. Review.
DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation.
Matthias Farlik, Florian Halbritter, +14 authors, Christoph Bock.
Cell Stem Cell, 2016 Nov 22; 19(6). PMID: 27867036    Free PMC article.
Highly Cited.
Herbivore-Induced DNA Demethylation Changes Floral Signalling and Attractiveness to Pollinators in Brassica rapa.
Roman T Kellenberger, Philipp M Schlüter, Florian P Schiestl.
PLoS One, 2016 Nov 22; 11(11). PMID: 27870873    Free PMC article.
Epigenetic changes as prognostic predictors in endometrial carcinomas.
Sanja A Farkas, Bengt G Sorbe, Torbjörn K Nilsson.
Epigenetics, 2016 Nov 23; 12(1). PMID: 27874289    Free PMC article.
Age-related epigenetic drift and phenotypic plasticity loss: implications in prevention of age-related human diseases.
Yuanyuan Li, Trygve O Tollefsbol.
Epigenomics, 2016 Nov 25; 8(12). PMID: 27882781    Free PMC article.
5-Hydroxymethylcytosine localizes to enhancer elements and is associated with survival in glioblastoma patients.
Kevin C Johnson, E Andres Houseman, +3 authors, Brock C Christensen.
Nat Commun, 2016 Nov 26; 7. PMID: 27886174    Free PMC article.
Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease.
N T Ventham, N A Kennedy, +10 authors, J Satsangi.
Nat Commun, 2016 Nov 26; 7. PMID: 27886173    Free PMC article.
Highly Cited.
TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1.
P-H Huang, P-J Lu, +8 authors, C-S Chen.
Oncogene, 2016 Nov 29; 36(16). PMID: 27893715
Genome-wide epigenomic profiling for biomarker discovery.
René A M Dirks, Hendrik G Stunnenberg, Hendrik Marks.
Clin Epigenetics, 2016 Nov 30; 8. PMID: 27895806    Free PMC article.
Review.
Increased DNA methylation variability in type 1 diabetes across three immune effector cell types.
Dirk S Paul, Andrew E Teschendorff, +42 authors, R David Leslie.
Nat Commun, 2016 Nov 30; 7. PMID: 27898055    Free PMC article.
Highly Cited.
SPlinted Ligation Adapter Tagging (SPLAT), a novel library preparation method for whole genome bisulphite sequencing.
Amanda Raine, Erika Manlig, +2 authors, Jessica Nordlund.
Nucleic Acids Res, 2016 Dec 03; 45(6). PMID: 27899585    Free PMC article.
Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.
Peter Stepper, Goran Kungulovski, +6 authors, Tomasz P Jurkowski.
Nucleic Acids Res, 2016 Dec 03; 45(4). PMID: 27899645    Free PMC article.
Highly Cited.
New differentially expressed genes and differential DNA methylation underlying refractory epilepsy.
Xi Liu, Shu Ou, +8 authors, Yangmei Chen.
Oncotarget, 2016 Dec 03; 7(52). PMID: 27903967    Free PMC article.
MethSMRT: an integrative database for DNA N6-methyladenine and N4-methylcytosine generated by single-molecular real-time sequencing.
Pohao Ye, Yizhao Luan, +3 authors, Zhi Xie.
Nucleic Acids Res, 2016 Dec 08; 45(D1). PMID: 27924023    Free PMC article.
Alternative roles for oxidized mCs and TETs.
Luisa Cimmino, Iannis Aifantis.
Curr Opin Genet Dev, 2016 Dec 13; 42. PMID: 27939598    Free PMC article.
Review.
Transcriptional programs that control expression of the autoimmune regulator gene Aire.
Yonatan Herzig, Shir Nevo, +18 authors, Jakub Abramson.
Nat Immunol, 2016 Dec 13; 18(2). PMID: 27941786
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.
Symen Ligthart, Carola Marzi, +86 authors, Abbas Dehghan.
Genome Biol, 2016 Dec 14; 17(1). PMID: 27955697    Free PMC article.
Highly Cited.
Uhrf1 controls the self-renewal versus differentiation of hematopoietic stem cells by epigenetically regulating the cell-division modes.
Jingyao Zhao, Xufeng Chen, +3 authors, Xiaolong Liu.
Proc Natl Acad Sci U S A, 2016 Dec 14; 114(2). PMID: 27956603    Free PMC article.
Functional evaluation of a PTSD-associated genetic variant: estradiol regulation and ADCYAP1R1.
K B Mercer, B Dias, +5 authors, K J Ressler.
Transl Psychiatry, 2016 Dec 14; 6(12). PMID: 27959335    Free PMC article.
Integrative modelling of tumour DNA methylation quantifies the contribution of metabolism.
Mahya Mehrmohamadi, Lucas K Mentch, Andrew G Clark, Jason W Locasale.
Nat Commun, 2016 Dec 15; 7. PMID: 27966532    Free PMC article.
The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review.
Ke-Xin Wen, Jelena Miliç, +12 authors, Oscar H Franco.
PLoS One, 2016 Dec 16; 11(12). PMID: 27973581    Free PMC article.
Systematic Review.
Genome recoding by tRNA modifications.
Francesca Tuorto, Frank Lyko.
Open Biol, 2016 Dec 16; 6(12). PMID: 27974624    Free PMC article.
Review.
Usefulness of DNA Methylation Levels in COASY and SPINT1 Gene Promoter Regions as Biomarkers in Diagnosis of Alzheimer's Disease and Amnestic Mild Cognitive Impairment.
Nobuyuki Kobayashi, Shunichiro Shinagawa, +8 authors, Kazuhiro Kondo.
PLoS One, 2016 Dec 20; 11(12). PMID: 27992572    Free PMC article.
Arabidopsis SWI/SNF chromatin remodeling complex binds both promoters and terminators to regulate gene expression.
Rafal Archacki, Ruslan Yatusevich, +8 authors, Szymon Swiezewski.
Nucleic Acids Res, 2016 Dec 21; 45(6). PMID: 27994035    Free PMC article.
The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells.
Mireia Jordà, Anna Díez-Villanueva, +6 authors, Miguel A Peinado.
Genome Res, 2016 Dec 22; 27(1). PMID: 27999094    Free PMC article.
Gene-Specific Methylation Analysis in Thymomas of Patients with Myasthenia Gravis.
Angela Lopomo, Roberta Ricciardi, +6 authors, Lucia Migliore.
Int J Mol Sci, 2016 Dec 22; 17(12). PMID: 27999265    Free PMC article.
NDRG4 hypermethylation is a potential biomarker for diagnosis and prognosis of gastric cancer in Chinese population.
Xiaoying Chen, Yong Yang, +8 authors, Shiwei Duan.
Oncotarget, 2017 Jan 04; 8(5). PMID: 28042954    Free PMC article.
Comparative analysis of DNA methylome and transcriptome of skeletal muscle in lean-, obese-, and mini-type pigs.
Yalan Yang, Guoming Liang, +6 authors, Kui Li.
Sci Rep, 2017 Jan 04; 7. PMID: 28045116    Free PMC article.
Linking the Epigenome with Exposure Effects and Susceptibility: The Epigenetic Seed and Soil Model.
Emma C Bowers, Shaun D McCullough.
Toxicol Sci, 2017 Jan 05; 155(2). PMID: 28049737    Free PMC article.
Review.
RHCG and TCAF1 promoter hypermethylation predicts biochemical recurrence in prostate cancer patients treated by radical prostatectomy.
Siri H Strand, Michal Switnicki, +11 authors, Karina D Sorensen.
Oncotarget, 2017 Jan 05; 8(4). PMID: 28052017    Free PMC article.
Cytosine methylation at CpCpG sites triggers accumulation of non-CpG methylation in gene bodies.
Nicolae Radu Zabet, Marco Catoni, Filippo Prischi, Jerzy Paszkowski.
Nucleic Acids Res, 2017 Jan 06; 45(7). PMID: 28053115    Free PMC article.
DNA methylation assessment from human slow- and fast-twitch skeletal muscle fibers.
Gwénaëlle Begue, Ulrika Raue, Bozena Jemiolo, Scott Trappe.
J Appl Physiol (1985), 2017 Jan 07; 122(4). PMID: 28057818    Free PMC article.
Genome-Wide DNA Methylation Patterns Analysis of Noncoding RNAs in Temporal Lobe Epilepsy Patients.
Wenbiao Xiao, Yuze Cao, +9 authors, Bo Xiao.
Mol Neurobiol, 2017 Jan 07; 55(1). PMID: 28058582
Mutated Chromatin Regulatory Factors as Tumor Drivers in Cancer.
Carl Koschmann, Felipe J Nunez, +4 authors, Maria G Castro.
Cancer Res, 2017 Jan 08; 77(2). PMID: 28062403    Free PMC article.
Review.
Analysis of DNA methylation in single circulating tumor cells.
C F Pixberg, K Raba, +15 authors, R P L Neves.
Oncogene, 2017 Jan 10; 36(23). PMID: 28068321
An epigenome-wide association analysis of cardiac autonomic responses among a population of welders.
Jinming Zhang, Zhonghua Liu, +6 authors, David C Christiani.
Epigenetics, 2017 Jan 12; 12(2). PMID: 28075199    Free PMC article.
Alternative transcription of sodium/bicarbonate transporter SLC4A7 gene enhanced by single nucleotide polymorphisms.
Hae Jeong Park, Soojung Lee, +2 authors, Inyeong Choi.
Physiol Genomics, 2017 Jan 15; 49(3). PMID: 28087757    Free PMC article.
The epigenetic basis of hematopoietic stem cell aging.
Ashley Kramer, Grant A Challen.
Semin Hematol, 2017 Jan 17; 54(1). PMID: 28088983    Free PMC article.
Review.
Single-Cell Multiomics: Multiple Measurements from Single Cells.
Iain C Macaulay, Chris P Ponting, Thierry Voet.
Trends Genet, 2017 Jan 17; 33(2). PMID: 28089370    Free PMC article.
Highly Cited. Review.
SPAG6 and L1TD1 are transcriptionally regulated by DNA methylation in non-small cell lung cancers.
Corinna Altenberger, Gerwin Heller, +12 authors, Sabine Zöchbauer-Müller.
Mol Cancer, 2017 Jan 18; 16(1). PMID: 28093071    Free PMC article.
DNA Methylation Analysis of BRD1 Promoter Regions and the Schizophrenia rs138880 Risk Allele.
Mads Dyrvig, Per Qvist, +4 authors, Jane H Christensen.
PLoS One, 2017 Jan 18; 12(1). PMID: 28095495    Free PMC article.
Mechanisms of metabolic memory and renal hypoxia as a therapeutic target in diabetic kidney disease.
Yosuke Hirakawa, Tetsuhiro Tanaka, Masaomi Nangaku.
J Diabetes Investig, 2017 Jan 18; 8(3). PMID: 28097824    Free PMC article.
Review.
Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine.
Gary G Chen, Jeffrey A Gross, +12 authors, Carl Ernst.
BMC Genomics, 2017 Jan 20; 18(1). PMID: 28100169    Free PMC article.
Prognostic relevance of SAMSN1 expression in gastric cancer.
Mitsuro Kanda, Dai Shimizu, +15 authors, Yasuhiro Kodera.
Oncol Lett, 2017 Jan 21; 12(6). PMID: 28105178    Free PMC article.
The 5-Hydroxymethylcytosine (5hmC) Reader UHRF2 Is Required for Normal Levels of 5hmC in Mouse Adult Brain and Spatial Learning and Memory.
Ruoyu Chen, Qiao Zhang, +14 authors, Jiemin Wong.
J Biol Chem, 2017 Jan 25; 292(11). PMID: 28115522    Free PMC article.
Body-hypomethylated human genes harbor extensive intragenic transcriptional activity and are prone to cancer-associated dysregulation.
Isabel Mendizabal, Jia Zeng, Thomas E Keller, Soojin V Yi.
Nucleic Acids Res, 2017 Jan 25; 45(8). PMID: 28115635    Free PMC article.
Reconsolidation and extinction: Using epigenetic signatures to challenge conventional wisdom.
Thekla J Hemstedt, K Matthew Lattal, Marcelo A Wood.
Neurobiol Learn Mem, 2017 Jan 26; 142(Pt A). PMID: 28119018    Free PMC article.
Review.
Epigenetic Alterations Affecting Transcription Factors and Signaling Pathways in Stromal Cells of Endometriosis.
Iveta Yotova, Emily Hsu, +6 authors, Benjamin Tycko.
PLoS One, 2017 Jan 27; 12(1). PMID: 28125717    Free PMC article.
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types.
Simone Ecker, Lu Chen, +22 authors, Dirk S Paul.
Genome Biol, 2017 Jan 28; 18(1). PMID: 28126036    Free PMC article.
Increased expression of prion protein gene is accompanied by demethylation of CpG sites in a mouse embryonal carcinoma cell line, P19C6.
Wuyun Dalai, Eiko Matsuo, +2 authors, Keiichi Saeki.
J Vet Med Sci, 2017 Jan 31; 79(3). PMID: 28132962    Free PMC article.
Effects of ionizing radiation on DNA methylation: from experimental biology to clinical applications.
Isabelle R Miousse, Kristy R Kutanzi, Igor Koturbash.
Int J Radiat Biol, 2017 Jan 31; 93(5). PMID: 28134023    Free PMC article.
Review.
Transcriptional heterogeneity in the lactase gene within cell-type is linked to the epigenome.
Edward Oh, Richie Jeremian, +7 authors, Viviane Labrie.
Sci Rep, 2017 Feb 01; 7. PMID: 28139744    Free PMC article.
Epigenetic Regulation of Axon Regeneration after Neural Injury.
Jung Eun Shin, Yongcheol Cho.
Mol Cells, 2017 Feb 06; 40(1). PMID: 28152303    Free PMC article.
Review.
Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemia.
Yan Li, Qingyu Xu, +7 authors, Li Yu.
J Hematol Oncol, 2017 Feb 06; 10(1). PMID: 28153026    Free PMC article.
Review.
TEA: the epigenome platform for Arabidopsis methylome study.
Sheng-Yao Su, Shu-Hwa Chen, +4 authors, Chung-Yen Lin.
BMC Genomics, 2017 Feb 06; 17(Suppl 13). PMID: 28155665    Free PMC article.
A whole-blood transcriptome meta-analysis identifies gene expression signatures of cigarette smoking.
Tianxiao Huan, Roby Joehanes, +30 authors, Daniel Levy.
Hum Mol Genet, 2017 Feb 06; 25(21). PMID: 28158590    Free PMC article.
Highly Cited.
Cold acclimation alters DNA methylation patterns and confers tolerance to heat and increases growth rate in Brassica rapa.
Tongkun Liu, Ying Li, +2 authors, Xilin Hou.
J Exp Bot, 2017 Feb 06; 68(5). PMID: 28158841    Free PMC article.
Hypermethylated LTR retrotransposon exhibits enhancer activity.
Tianxiang Hu, Xingguo Zhu, +3 authors, Dorothy Tuan.
Epigenetics, 2017 Feb 07; 12(3). PMID: 28165867    Free PMC article.
Modeling complex patterns of differential DNA methylation that associate with gene expression changes.
Christopher E Schlosberg, Nathan D VanderKraats, John R Edwards.
Nucleic Acids Res, 2017 Feb 09; 45(9). PMID: 28168293    Free PMC article.
PITX3 DNA methylation is an independent predictor of overall survival in patients with head and neck squamous cell carcinoma.
Verena Sailer, Emily Eva Holmes, +8 authors, Dimo Dietrich.
Clin Epigenetics, 2017 Feb 09; 9. PMID: 28174607    Free PMC article.
Constitutional Epi/Genetic Conditions: Genetic, Epigenetic, and Environmental Factors.
Laila C Schenkel, David Rodenhiser, +3 authors, Bekim Sadikovic.
J Pediatr Genet, 2017 Feb 10; 6(1). PMID: 28180025    Free PMC article.
Review.
Improved regulatory element prediction based on tissue-specific local epigenomic signatures.
Yupeng He, David U Gorkin, +8 authors, Joseph R Ecker.
Proc Natl Acad Sci U S A, 2017 Feb 15; 114(9). PMID: 28193886    Free PMC article.
Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study.
Kim V E Braun, Klodian Dhana, +8 authors, Abbas Dehghan.
Clin Epigenetics, 2017 Feb 15; 9. PMID: 28194238    Free PMC article.
DNA methylation as a putative mechanism for reduced dendritic spine density in the superior temporal gyrus of subjects with schizophrenia.
B McKinney, Y Ding, D A Lewis, R A Sweet.
Transl Psychiatry, 2017 Feb 15; 7(2). PMID: 28195572    Free PMC article.
Hypoxia inducible factors regulate the transcription of the sprouty2 gene and expression of the sprouty2 protein.
Xianlong Gao, Kristin C Hicks, Paul Neumann, Tarun B Patel.
PLoS One, 2017 Feb 15; 12(2). PMID: 28196140    Free PMC article.
Genetic epidemiology in kidney disease.
Hannah C Ainsworth, Carl D Langefeld, Barry I Freedman.
Nephrol Dial Transplant, 2017 Feb 16; 32(suppl_2). PMID: 28201750    Free PMC article.
Review.
Methyl donor supplementation alters cognitive performance and motivation in female offspring from high-fat diet-fed dams.
Sarah E McKee, Nicola M Grissom, Christopher T Herdt, Teresa M Reyes.
FASEB J, 2017 Feb 18; 31(6). PMID: 28209774    Free PMC article.
Epigenetic Landscape during Coronavirus Infection.
Alexandra Schäfer, Ralph S Baric.
Pathogens, 2017 Feb 18; 6(1). PMID: 28212305    Free PMC article.
A Bayesian Approach for Analysis of Whole-Genome Bisulfite Sequencing Data Identifies Disease-Associated Changes in DNA Methylation.
Owen J L Rackham, Sarah R Langley, +7 authors, Enrico Petretto.
Genetics, 2017 Feb 19; 205(4). PMID: 28213474    Free PMC article.
Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects.
Cajsa Davegårdh, Christa Broholm, +17 authors, Charlotte Ling.
BMC Med, 2017 Feb 23; 15(1). PMID: 28222718    Free PMC article.
Distal CpG islands can serve as alternative promoters to transcribe genes with silenced proximal promoters.
Shrutii Sarda, Avinash Das, Charles Vinson, Sridhar Hannenhalli.
Genome Res, 2017 Feb 23; 27(4). PMID: 28223400    Free PMC article.
Intragenic CpG islands play important roles in bivalent chromatin assembly of developmental genes.
Sun-Min Lee, Jungwoo Lee, +7 authors, Young-Joon Kim.
Proc Natl Acad Sci U S A, 2017 Feb 23; 114(10). PMID: 28223506    Free PMC article.
Epigenetic characteristics of the mitotic chromosome in 1D and 3D.
Marlies E Oomen, Job Dekker.
Crit Rev Biochem Mol Biol, 2017 Feb 24; 52(2). PMID: 28228067    Free PMC article.
Review.
RhMKK9, a rose MAP KINASE KINASE gene, is involved in rehydration-triggered ethylene production in rose gynoecia.
Jiwei Chen, Qian Zhang, +9 authors, Nan Ma.
BMC Plant Biol, 2017 Feb 25; 17(1). PMID: 28231772    Free PMC article.
Epigenome-wide cross-tissue predictive modeling and comparison of cord blood and placental methylation in a birth cohort.
Margherita M De Carli, Andrea A Baccarelli, +8 authors, Allan C Just.
Epigenomics, 2017 Feb 25; 9(3). PMID: 28234020    Free PMC article.
Epigenetics studies of fetal alcohol spectrum disorder: where are we now?
Alexandre A Lussier, Joanne Weinberg, Michael S Kobor.
Epigenomics, 2017 Feb 25; 9(3). PMID: 28234026    Free PMC article.
Review.
Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module.
Dongli Liang, Zhaoxia Wang, +5 authors, Zhongdong Qiao.
Sci Rep, 2017 Mar 03; 7. PMID: 28252009    Free PMC article.
Methylome-wide association study of whole blood DNA in the Norfolk Island isolate identifies robust loci associated with age.
Miles C Benton, Heidi G Sutherland, +3 authors, Lyn R Griffiths.
Aging (Albany NY), 2017 Mar 04; 9(3). PMID: 28255110    Free PMC article.
Locus- and cell type-specific epigenetic switching during cellular differentiation in mammals.
Ying-Tao Zhao, Maria Fasolino, Zhaolan Zhou.
Front Biol (Beijing), 2017 Mar 07; 11(4). PMID: 28261266    Free PMC article.
Epigenetic Mechanisms of Transmission of Metabolic Disease across Generations.
Vicencia Micheline Sales, Anne C Ferguson-Smith, Mary-Elizabeth Patti.
Cell Metab, 2017 Mar 09; 25(3). PMID: 28273478    Free PMC article.
Highly Cited. Review.
Identification of endometrial cancer methylation features using combined methylation analysis methods.
Michael P Trimarchi, Pearlly Yan, +2 authors, Paul J Goodfellow.
PLoS One, 2017 Mar 10; 12(3). PMID: 28278225    Free PMC article.
Methylation of avpr1a in the cortex of wild prairie voles: effects of CpG position and polymorphism.
M Okhovat, S M Maguire, S M Phelps.
R Soc Open Sci, 2017 Mar 11; 4(1). PMID: 28280564    Free PMC article.
Identification of epigenetic signature associated with alpha thalassemia/mental retardation X-linked syndrome.
Laila C Schenkel, Kristin D Kernohan, +10 authors, Bekim Sadikovic.
Epigenetics Chromatin, 2017 Mar 16; 10. PMID: 28293299    Free PMC article.
Identification of an atypical etiological head and neck squamous carcinoma subtype featuring the CpG island methylator phenotype.
K Brennan, J L Koenig, +2 authors, O Gevaert.
EBioMedicine, 2017 Mar 21; 17. PMID: 28314692    Free PMC article.
Protective vaccination and blood-stage malaria modify DNA methylation of gene promoters in the liver of Balb/c mice.
Saleh Al-Quraishy, Mohamed A Dkhil, +5 authors, Marcos J Araúzo-Bravo.
Parasitol Res, 2017 Mar 21; 116(5). PMID: 28315013
Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies.
Matthew Machin, André F S Amaral, +8 authors, ALEC study.
BMC Pulm Med, 2017 Mar 23; 17(1). PMID: 28320365    Free PMC article.
Systematic Review.
Neuroanatomic, epigenetic and genetic differences in monozygotic twins discordant for attention deficit hyperactivity disorder.
Y-C Chen, G Sudre, +5 authors, P Shaw.
Mol Psychiatry, 2017 Mar 23; 23(3). PMID: 28322272    Free PMC article.
Specific and Stable Suppression of HIV Provirus Expression In Vitro by Chimeric Zinc Finger DNA Methyltransferase 1.
Junxiao Deng, Xiying Qu, +11 authors, Huanzhang Zhu.
Mol Ther Nucleic Acids, 2017 Mar 23; 6. PMID: 28325289    Free PMC article.
The epigenetic landscape of clear-cell renal cell carcinoma.
Katarzyna Kluzek, Hans A Bluyssen, Joanna Wesoly.
J Kidney Cancer VHL, 2015 Jan 01; 2(3). PMID: 28326264    Free PMC article.
Molecular Evidence for Differential Long-term Outcomes of Early Life Severe Acute Malnutrition.
Allan Sheppard, Sherry Ngo, +5 authors, Terrence Forrester.
EBioMedicine, 2017 Mar 24; 18. PMID: 28330812    Free PMC article.
A survey of the approaches for identifying differential methylation using bisulfite sequencing data.
Adib Shafi, Cristina Mitrea, Tin Nguyen, Sorin Draghici.
Brief Bioinform, 2017 Mar 24; 19(5). PMID: 28334228    Free PMC article.
Review.
Dynamic changes in chromatin states during specification and differentiation of adult intestinal stem cells.
Juri Kazakevych, Sergi Sayols, +2 authors, Natalia Soshnikova.
Nucleic Acids Res, 2017 Mar 24; 45(10). PMID: 28334816    Free PMC article.
Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo.
Jesper L V Maag, Dominik C Kaczorowski, +4 authors, Marcel E Dinger.
BMC Genomics, 2017 Mar 25; 18(1). PMID: 28335720    Free PMC article.
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism.
Oliver Hahn, Sebastian Grönke, +9 authors, Linda Partridge.
Genome Biol, 2017 Mar 30; 18(1). PMID: 28351387    Free PMC article.
Highly Cited.
The epigenetic landscape of age-related diseases: the geroscience perspective.
Noémie Gensous, Maria Giulia Bacalini, +8 authors, Paolo Garagnani.
Biogerontology, 2017 Mar 30; 18(4). PMID: 28352958    Free PMC article.
Review.
DNA methylation aberrancies as a guide for surveillance and treatment of human cancers.
Gangning Liang, Daniel J Weisenberger.
Epigenetics, 2017 Mar 31; 12(6). PMID: 28358281    Free PMC article.
Review.
The double-edged sword of (re)expression of genes by hypomethylating agents: from viral mimicry to exploitation as priming agents for targeted immune checkpoint modulation.
Florian Wolff, Michael Leisch, +2 authors, Lisa Pleyer.
Cell Commun Signal, 2017 Apr 01; 15(1). PMID: 28359286    Free PMC article.
Review.
Simultaneous mapping of active DNA demethylation and sister chromatid exchange in single cells.
Xiaoji Wu, Azusa Inoue, Tsukasa Suzuki, Yi Zhang.
Genes Dev, 2017 Apr 01; 31(5). PMID: 28360182    Free PMC article.
Epigenetic signatures of gestational diabetes mellitus on cord blood methylation.
Larissa Haertle, Nady El Hajj, +4 authors, Thomas Haaf.
Clin Epigenetics, 2017 Apr 01; 9. PMID: 28360945    Free PMC article.
Migration phenology and breeding success are predicted by methylation of a photoperiodic gene in the barn swallow.
Nicola Saino, Roberto Ambrosini, +11 authors, Diego Rubolini.
Sci Rep, 2017 Apr 01; 7. PMID: 28361883    Free PMC article.
The preferred nucleotide contexts of the AID/APOBEC cytidine deaminases have differential effects when mutating retrotransposon and virus sequences compared to host genes.
Jeffrey Chen, Thomas MacCarthy.
PLoS Comput Biol, 2017 Apr 01; 13(3). PMID: 28362825    Free PMC article.
Using DNA Methylation Profiling to Evaluate Biological Age and Longevity Interventions.
Daniel A Petkovich, Dmitriy I Podolskiy, +3 authors, Vadim N Gladyshev.
Cell Metab, 2017 Apr 06; 25(4). PMID: 28380383    Free PMC article.
Highly Cited.
NELL1, whose high expression correlates with negative outcomes, has different methylation patterns in alveolar and embryonal rhabdomyosarcoma.
Lucia Tombolan, Elena Poli, +4 authors, Gerolamo Lanfranchi.
Oncotarget, 2017 Apr 06; 8(20). PMID: 28380437    Free PMC article.
Comprehensive characterization of DNA methylation changes in Fuchs endothelial corneal dystrophy.
Emily Khuc, Russell Bainer, +6 authors, Matilda F Chan.
PLoS One, 2017 Apr 07; 12(4). PMID: 28384203    Free PMC article.
Dnmt3a haploinsufficiency cooperates with oncogenic Kras to promote an early-onset T-cell acute lymphoblastic leukemia.
Yuan-I Chang, Guangyao Kong, +3 authors, Jing Zhang.
Am J Transl Res, 2017 Apr 08; 9(3). PMID: 28386358    Free PMC article.
Genome-wide hepatic DNA methylation changes in high-fat diet-induced obese mice.
AhRam Yoon, Stephanie A Tammen, +2 authors, Sang-Woon Choi.
Nutr Res Pract, 2017 Apr 08; 11(2). PMID: 28386383    Free PMC article.
Shaping the cellular landscape with Set2/SETD2 methylation.
Stephen L McDaniel, Brian D Strahl.
Cell Mol Life Sci, 2017 Apr 08; 74(18). PMID: 28386724    Free PMC article.
Review.
Non-linear patterns in age-related DNA methylation may reflect CD4+ T cell differentiation.
Nicholas D Johnson, Howard W Wiener, +5 authors, Karen N Conneely.
Epigenetics, 2017 Apr 08; 12(6). PMID: 28387568    Free PMC article.
DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning.
Christof Angermueller, Heather J Lee, Wolf Reik, Oliver Stegle.
Genome Biol, 2017 Apr 12; 18(1). PMID: 28395661    Free PMC article.
Highly Cited.
Systemic evaluation of cellular reprogramming processes exploiting a novel R-tool: eegc.
Xiaoyuan Zhou, Guofeng Meng, Christine Nardini, Hongkang Mei.
Bioinformatics, 2017 Apr 12; 33(16). PMID: 28398503    Free PMC article.
GAD1 Upregulation Programs Aggressive Features of Cancer Cell Metabolism in the Brain Metastatic Microenvironment.
Patricia M Schnepp, Dennis D Lee, +7 authors, Siyuan Zhang.
Cancer Res, 2017 Apr 13; 77(11). PMID: 28400476    Free PMC article.
Epigenetic Regulations in Diabetic Nephropathy.
Zeyuan Lu, Na Liu, Feng Wang.
J Diabetes Res, 2017 Apr 13; 2017. PMID: 28401169    Free PMC article.
Review.
DNA methylation and its role in the pathogenesis of diabetes.
Amita Bansal, Sara E Pinney.
Pediatr Diabetes, 2017 Apr 13; 18(3). PMID: 28401680    Free PMC article.
Review.
Diet and microbiota in inflammatory bowel disease: The gut in disharmony.
Davy C M Rapozo, Claudio Bernardazzi, Heitor Siffert Pereira de Souza.
World J Gastroenterol, 2017 Apr 14; 23(12). PMID: 28405140    Free PMC article.
Review.
Systemic analysis of osteoblast-specific DNA methylation marks reveals novel epigenetic basis of osteoblast differentiation.
Fangtang Yu, Hui Shen, Hong-Wen Deng.
Bone Rep, 2017 Apr 15; 6. PMID: 28409176    Free PMC article.
Links between DNA methylation and nucleosome occupancy in the human genome.
Clayton K Collings, John N Anderson.
Epigenetics Chromatin, 2017 Apr 18; 10. PMID: 28413449    Free PMC article.
DNA methylation of METTL7A gene body regulates its transcriptional level in thyroid cancer.
Shasha Zhou, Yihang Shen, +4 authors, Pin Li.
Oncotarget, 2017 Apr 19; 8(21). PMID: 28416772    Free PMC article.
Meta-analysis of possible role of cadherin gene methylation in evolution and prognosis of hepatocellular carcinoma with a PRISMA guideline.
Chunxiao Zhu, Xuefeng Feng, Guoliang Ye, Tao Huang.
Medicine (Baltimore), 2017 Apr 20; 96(16). PMID: 28422868    Free PMC article.
DNA methylation intratumor heterogeneity in localized lung adenocarcinomas.
Kelly Quek, Jun Li, +15 authors, Jianjun Zhang.
Oncotarget, 2017 Apr 21; 8(13). PMID: 28423542    Free PMC article.
Genome-wide DNA methylation analysis reveals molecular subtypes of pancreatic cancer.
Nitish Kumar Mishra, Chittibabu Guda.
Oncotarget, 2017 Apr 21; 8(17). PMID: 28423671    Free PMC article.
DNA methylation directly downregulates human cathelicidin antimicrobial peptide gene (CAMP) promoter activity.
Xi Chen, Guangying Qi, +7 authors, Xianqiong Zou.
Oncotarget, 2017 Apr 22; 8(17). PMID: 28427192    Free PMC article.
Comparative Analysis of Ralstonia solanacearum Methylomes.
Ivan Erill, Marina Puigvert, +6 authors, Marc Valls.
Front Plant Sci, 2017 Apr 30; 8. PMID: 28450872    Free PMC article.
The Effects of CpG Densities around Transcription Start Sites on Sex-Biased Gene Expression in Poecilia reticulata.
Katsunori Tamagawa, Takashi Makino, Masakado Kawata.
Genome Biol Evol, 2017 Apr 30; 9(5). PMID: 28453630    Free PMC article.
Comparison of DNA Methylation in Schwann Cells before and after Peripheral Nerve Injury in Rats.
Xian-Hu Zhou, Wei Lin, +7 authors, Shi-Qing Feng.
Biomed Res Int, 2017 May 02; 2017. PMID: 28459064    Free PMC article.
Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas.
Caroline Moraes Beltrami, Mariana Bisarro Dos Reis, +7 authors, Silvia Regina Rogatto.
Clin Epigenetics, 2017 May 05; 9. PMID: 28469731    Free PMC article.
Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment.
Justin J-L Wong, Dadi Gao, +9 authors, John E J Rasko.
Nat Commun, 2017 May 10; 8. PMID: 28480880    Free PMC article.
Placental lipoprotein lipase DNA methylation alterations are associated with gestational diabetes and body composition at 5 years of age.
Valérie Gagné-Ouellet, Andrée-Anne Houde, +7 authors, Luigi Bouchard.
Epigenetics, 2017 May 10; 12(8). PMID: 28486003    Free PMC article.
Potential role of DNA methylation as a facilitator of target search processes for transcription factors through interplay with methyl-CpG-binding proteins.
Catherine A Kemme, Rolando Marquez, Ross H Luu, Junji Iwahara.
Nucleic Acids Res, 2017 May 10; 45(13). PMID: 28486614    Fre