. 2012 Oct; 23 Suppl 6:vi7-12.
doi: 10.1093/annonc/mds187.

Triple-negative breast cancer: epidemiological considerations and recommendations

P Boyle 1 
  • PMID: 23012306
  •     190 citations


Breast cancer is a major problem for global public health. Breast Cancer is the most common incident form of cancer in women around the world. The incidence is increasing while mortality is declining in many high-income countries. The last decade has seen a revolution in the understanding of breast cancer, with new classifications proposed that have significant prognostic value and provide guides to treatment options. Breast cancers that demonstrate the absence of oestrogen receptor and progesterone receptor and no overexpression of human epidermal growth factor receptor 2 (HER2) are referred to as triple-negative breast cancer (TNBC). There is now evidence emerging from epidemiological studies regarding important characteristics of this group of tumours that carry a relatively poorer prognosis than the major breast cancer sub-types. From this review of available data and information, there are some consistent findings that emerge. Women with TNBC experience the peak risk of recurrence within 3 years of diagnosis, and the mortality rates appear to be increased for 5 years after diagnosis. TNBC represents 10%-20% of invasive breast cancers and has been associated with African-American race, deprivation status, younger age at diagnosis, more advanced disease stage, higher grade, high mitotic indices, family history of breast cancer and BRCA1 mutations. TNBC is regularly reported to be three times more common in women of African descent and in pre-menopausal women, and carries a poorer prognosis than other forms of breast cancer. Although prospects for prevention of non-hormone-dependent breast cancer are currently poor, it is still important to understand the aetiology of such tumours. There remains a great deal of work to be done to arrive at a comprehensive picture of the aetiology of breast cancer. Key recommendations are that there is a clear and urgent need to have more epidemiological studies of the breast cancer sub-types to integrate aetiological and lifestyle factors for prevention of incidence and death, and to have more population-based information of the clinical and biological relevance from cancer registries.

Relative and disease-free survival for breast cancer in relation to subtype: a population-based study.
Pamela Minicozzi, Francesca Bella, +10 authors, Milena Sant.
J Cancer Res Clin Oncol, 2013 Jul 31; 139(9). PMID: 23892409
Breast cancer molecular subtypes and survival in a hospital-based sample in Puerto Rico.
Ana Patricia Ortiz, Orquidea Frías, +7 authors, Erick Suárez.
Cancer Med, 2013 Aug 10; 2(3). PMID: 23930211    Free PMC article.
Genomic insights into triple-negative and HER2-positive breast cancers using isogenic model systems.
Prakriti Mudvari, Kazufumi Ohshiro, +2 authors, Rakesh Kumar.
PLoS One, 2013 Oct 03; 8(9). PMID: 24086418    Free PMC article.
Adherence to treatment guidelines and survival in triple-negative breast cancer: a retrospective multi-center cohort study with 9,156 patients.
Lukas Schwentner, Achim Wöckel, +6 authors, Brenda study group.
BMC Cancer, 2013 Oct 22; 13. PMID: 24138748    Free PMC article.
Layer-by-layer nanoparticles for systemic codelivery of an anticancer drug and siRNA for potential triple-negative breast cancer treatment.
Zhou J Deng, Stephen W Morton, +3 authors, Paula T Hammond.
ACS Nano, 2013 Oct 23; 7(11). PMID: 24144228    Free PMC article.
Highly Cited.
Evaluating many treatments and biomarkers in oncology: a new design.
Richard Kaplan, Timothy Maughan, +4 authors, Mahesh Parmar.
J Clin Oncol, 2013 Nov 20; 31(36). PMID: 24248692    Free PMC article.
Differences in gene and protein expression and the effects of race/ethnicity on breast cancer subtypes.
Mariana Chavez-Macgregor, Shuying Liu, +9 authors, Ana M Gonzalez-Angulo.
Cancer Epidemiol Biomarkers Prev, 2013 Dec 04; 23(2). PMID: 24296856    Free PMC article.
Increased expression of mdig predicts poorer survival of the breast cancer patients.
Chitra Thakur, Yongju Lu, +3 authors, Fei Chen.
Gene, 2013 Dec 07; 535(2). PMID: 24309373    Free PMC article.
ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis.
Mathilde Romagnoli, Nora D Mineva, +13 authors, Gail E Sonenshein.
EMBO Mol Med, 2014 Jan 01; 6(2). PMID: 24375628    Free PMC article.
Cancer cluster investigations: review of the past and proposals for the future.
Michael Goodman, Judy S LaKind, +9 authors, Donald R Mattison.
Int J Environ Res Public Health, 2014 Jan 31; 11(2). PMID: 24477211    Free PMC article.
Triple-negative breast cancer risk in women is defined by the defect of estrogen signaling: preventive and therapeutic implications.
Zsuzsanna Suba.
Onco Targets Ther, 2014 Feb 01; 7. PMID: 24482576    Free PMC article.
Doubling down on the PI3K-AKT-mTOR pathway enhances the antitumor efficacy of PARP inhibitor in triple negative breast cancer model beyond BRCA-ness.
Pradip De, Yuling Sun, +3 authors, Nandini Dey.
Neoplasia, 2014 Feb 25; 16(1). PMID: 24563619    Free PMC article.
The effect and mechanism of tamoxifen-induced hepatocyte steatosis in vitro.
Fei Zhao, Ping Xie, +3 authors, Yutao Zhan.
Int J Mol Sci, 2014 Mar 08; 15(3). PMID: 24603540    Free PMC article.
Multidrug-resistant breast cancer: current perspectives.
Heather L Martin, Laura Smith, Darren C Tomlinson.
Breast Cancer (Dove Med Press), 2014 Mar 22; 6. PMID: 24648765    Free PMC article.
Meta-analysis on the association between pathologic complete response and triple-negative breast cancer after neoadjuvant chemotherapy.
Kunpeng Wu, Qiaozhu Yang, +2 authors, Zhixiong Yang.
World J Surg Oncol, 2014 Apr 16; 12. PMID: 24731479    Free PMC article.
US incidence of breast cancer subtypes defined by joint hormone receptor and HER2 status.
Nadia Howlader, Sean F Altekruse, +4 authors, Kathleen A Cronin.
J Natl Cancer Inst, 2014 Apr 30; 106(5). PMID: 24777111    Free PMC article.
Highly Cited.
Suicide HSVtk gene delivery by neurotensin-polyplex nanoparticles via the bloodstream and GCV Treatment specifically inhibit the growth of human MDA-MB-231 triple negative breast cancer tumors xenografted in athymic mice.
Rosa A Castillo-Rodríguez, Martha L Arango-Rodríguez, +4 authors, Daniel Martínez-Fong.
PLoS One, 2014 May 16; 9(5). PMID: 24824754    Free PMC article.
Synergistic therapeutic effect of cisplatin and phosphatidylinositol 3-kinase (PI3K) inhibitors in cancer growth and metastasis of Brca1 mutant tumors.
Athanassios Vassilopoulos, Cuiying Xiao, +5 authors, Chu-Xia Deng.
J Biol Chem, 2014 Jul 10; 289(35). PMID: 25006250    Free PMC article.
Incidence and mortality of female breast cancer in the Asia-Pacific region.
Danny R Youlden, Susanna M Cramb, Cheng Har Yip, Peter D Baade.
Cancer Biol Med, 2014 Jul 11; 11(2). PMID: 25009752    Free PMC article.
Highly Cited.
Case Report of Pulmonary Sarcoidosis Suspected to be Pulmonary Metastasis in a Patient with Breast Cancer.
Hye Sook Kim, Suk-Young Lee, +3 authors, Jae Hong Seo.
Cancer Res Treat, 2014 Jul 21; 46(3). PMID: 25038768    Free PMC article.
miR-638 mediated regulation of BRCA1 affects DNA repair and sensitivity to UV and cisplatin in triple-negative breast cancer.
Xiaohui Tan, Jin Peng, +7 authors, Sidney W Fu.
Breast Cancer Res, 2014 Sep 18; 16(5). PMID: 25228385    Free PMC article.
Breast cancer control in China: challenges and opportunities of the use of population-based routine data studies.
Ana Catarina Pinto, Rita Canário, Paula Fidalgo.
J Thorac Dis, 2014 Oct 03; 6(9). PMID: 25276355    Free PMC article.
Teriflunomide, an immunomodulatory drug, exerts anticancer activity in triple negative breast cancer cells.
Ou Huang, Weili Zhang, +6 authors, Min Jiang.
Exp Biol Med (Maywood), 2014 Oct 12; 240(4). PMID: 25304315    Free PMC article.
Effect of Withania somnifera root extract on spontaneous estrogen receptor-negative mammary cancer in MMTV/Neu mice.
Kamel F Khazal, Donald L Hill, Clinton J Grubbs.
Anticancer Res, 2014 Nov 05; 34(11). PMID: 25368231    Free PMC article.
Combined phosphoproteomics and bioinformatics strategy in deciphering drug resistant related pathways in triple negative breast cancer.
Xinyu Deng, Morris Kohanfars, +4 authors, Helena R Chang.
Int J Proteomics, 2014 Dec 06; 2014. PMID: 25478227    Free PMC article.
The HER2 Signaling Network in Breast Cancer--Like a Spider in its Web.
A Dittrich, H Gautrey, D Browell, A Tyson-Capper.
J Mammary Gland Biol Neoplasia, 2014 Dec 30; 19(3-4). PMID: 25544707
Role of positron emission tomography for the monitoring of response to therapy in breast cancer.
Olivier Humbert, Alexandre Cochet, +4 authors, Pierre Fumoleau.
Oncologist, 2015 Jan 07; 20(2). PMID: 25561512    Free PMC article.
Persistent organic pollutants and obesity: are they potential mechanisms for breast cancer promotion?
Denise K Reaves, Erika Ginsburg, John J Bang, Jodie M Fleming.
Endocr Relat Cancer, 2015 Jan 28; 22(2). PMID: 25624167    Free PMC article.
Triple-negative breast cancer in African-American women: disparities versus biology.
Eric C Dietze, Christopher Sistrunk, +2 authors, Victoria L Seewaldt.
Nat Rev Cancer, 2015 Feb 13; 15(4). PMID: 25673085    Free PMC article.
Highly Cited. Review.
Characterization of macrophage--cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer.
Maija Hollmén, Filip Roudnicky, Sinem Karaman, Michael Detmar.
Sci Rep, 2015 Mar 18; 5. PMID: 25776849    Free PMC article.
The association of alcohol consumption with mammographic density in a multiethnic urban population.
Zoe Quandt, Julie D Flom, +3 authors, Jasmine A McDonald.
BMC Cancer, 2015 Mar 18; 15. PMID: 25777420    Free PMC article.
Establishment and characterization of a new cell line of canine inflammatory mammary cancer: IPC-366.
Sara Caceres, Laura Peña, +5 authors, Juan C Illera.
PLoS One, 2015 Mar 26; 10(3). PMID: 25807360    Free PMC article.
Clinical and molecular characteristics of triple-negative breast cancer patients in Northern Israel: single center experience.
Karama Asleh-Aburaya, Georgeta Fried.
Springerplus, 2015 Apr 01; 4. PMID: 25825688    Free PMC article.
Circulating cell-free miRNAs as biomarker for triple-negative breast cancer.
V Y Shin, J M Siu, +2 authors, A Kwong.
Br J Cancer, 2015 Apr 24; 112(11). PMID: 25906045    Free PMC article.
Genome-wide association study of susceptibility loci for breast cancer in Sardinian population.
Grazia Palomba, Angela Loi, +27 authors, Giuseppe Palmieri.
BMC Cancer, 2015 May 10; 15. PMID: 25956309    Free PMC article.
Role of IGF1R in Breast Cancer Subtypes, Stemness, and Lineage Differentiation.
Susan M Farabaugh, David N Boone, Adrian V Lee.
Front Endocrinol (Lausanne), 2015 May 13; 6. PMID: 25964777    Free PMC article.
Highly Cited. Review.
An Autoimmune Response Signature Associated with the Development of Triple-Negative Breast Cancer Reflects Disease Pathogenesis.
Hiroyuki Katayama, Clayton Boldt, +11 authors, Samir Hanash.
Cancer Res, 2015 Jun 20; 75(16). PMID: 26088128    Free PMC article.
Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells.
Jessica Swanner, Jade Mims, +4 authors, Ravi N Singh.
Int J Nanomedicine, 2015 Jul 18; 10. PMID: 26185437    Free PMC article.
Targeting Insulin-Like Growth Factor Binding Protein-3 Signaling in Triple-Negative Breast Cancer.
Kamila A Marzec, Robert C Baxter, Janet L Martin.
Biomed Res Int, 2015 Jul 30; 2015. PMID: 26221601    Free PMC article.
Higher locoregional recurrence rate for triple-negative breast cancer following neoadjuvant chemotherapy, surgery and radiotherapy.
Chi Zhang, Shuang Wang, +7 authors, Eileen P Connolly.
Springerplus, 2015 Aug 05; 4. PMID: 26240784    Free PMC article.
Breast cancer survival in African-American women by hormone receptor subtypes.
Tomi Akinyemiju, Justin Xavier Moore, Sean F Altekruse.
Breast Cancer Res Treat, 2015 Aug 08; 153(1). PMID: 26250393    Free PMC article.
Cripto-1 in TNBC.
Nadia P Castro, David S Salomon.
Aging (Albany NY), 2015 Aug 25; 7(8). PMID: 26298547    Free PMC article.
Modifiable Lifestyle Factors and Triple-negative Breast Cancer Survival: A Population-based Prospective Study.
Ping-Ping Bao, Gen-Ming Zhao, +4 authors, Ying Zheng.
Epidemiology, 2015 Sep 12; 26(6). PMID: 26360370    Free PMC article.
Piperlongumine for Enhancing Oral Bioavailability and Cytotoxicity of Docetaxel in Triple-Negative Breast Cancer.
Ketan Patel, Nusrat Chowdhury, +3 authors, Mandip Singh.
J Pharm Sci, 2015 Sep 16; 104(12). PMID: 26372815    Free PMC article.
The dog as a naturally-occurring model for insulin-like growth factor type 1 receptor-overexpressing breast cancer: an observational cohort study.
Laetitia Jaillardon, Jérome Abadie, +4 authors, Frédérique Nguyen.
BMC Cancer, 2015 Oct 10; 15. PMID: 26449867    Free PMC article.
Body mass index and weight change in relation to triple-negative breast cancer survival.
Ping-Ping Bao, Hui Cai, +4 authors, Ying Zheng.
Cancer Causes Control, 2015 Dec 02; 27(2). PMID: 26621544    Free PMC article.
miR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response.
Alessandra Cataldo, Douglas G Cheung, +5 authors, Carlo M Croce.
Oncotarget, 2015 Dec 02; 7(1). PMID: 26623722    Free PMC article.
Risk factors and biomarkers of life-threatening cancers.
Philippe Autier.
Ecancermedicalscience, 2015 Dec 05; 9. PMID: 26635900    Free PMC article.
Disparities in Breast Cancer Incidence, Mortality, and Quality of Care among African American and European American Women in South Carolina.
Marsha E Samson, Nancy G Porter, +2 authors, Jan M Eberth.
South Med J, 2016 Jan 08; 109(1). PMID: 26741869    Free PMC article.
Orlistat and antisense-miRNA-loaded PLGA-PEG nanoparticles for enhanced triple negative breast cancer therapy.
Aarohi Bhargava-Shah, Kira Foygel, Rammohan Devulapally, Ramasamy Paulmurugan.
Nanomedicine (Lond), 2016 Jan 21; 11(3). PMID: 26787319    Free PMC article.
Potential therapeutic implications of IL-6/IL-6R/gp130-targeting agents in breast cancer.
Tae-Hwe Heo, Joseph Wahler, Nanjoo Suh.
Oncotarget, 2016 Feb 04; 7(13). PMID: 26840088    Free PMC article.
Risk of regional recurrence in triple-negative breast cancer patients: a Dutch cohort study.
Lori M van Roozendaal, Leonie H M Smit, +6 authors, Marjolein L Smidt.
Breast Cancer Res Treat, 2016 Mar 26; 156(3). PMID: 27013474    Free PMC article.
New insights into the prognostic value of Ki-67 labeling index in patients with triple-negative breast cancer.
Shuang Hao, Zhi-Xian He, +2 authors, Zhi-Min Shao.
Oncotarget, 2016 Apr 07; 7(17). PMID: 27050075    Free PMC article.
cMET inhibitor crizotinib impairs angiogenesis and reduces tumor burden in the C3(1)-Tag model of basal-like breast cancer.
Alyssa J Cozzo, Sneha Sundaram, +10 authors, Liza Makowski.
Springerplus, 2016 Apr 09; 5. PMID: 27057482    Free PMC article.
Role of the androgen receptor in triple-negative breast cancer.
Murtuza Rampurwala, Kari B Wisinski, Ruth O'Regan.
Clin Adv Hematol Oncol, 2016 Apr 09; 14(3). PMID: 27058032    Free PMC article.
Targeting a Cancer-Specific Epitope of the Epidermal Growth Factor Receptor in Triple-Negative Breast Cancer.
Nathan Simon, Antonella Antignani, +2 authors, David FitzGerald.
J Natl Cancer Inst, 2016 Apr 15; 108(8). PMID: 27075852    Free PMC article.
G-CSF regulates macrophage phenotype and associates with poor overall survival in human triple-negative breast cancer.
Maija Hollmén, Sinem Karaman, +6 authors, Michael Detmar.
Oncoimmunology, 2016 May 04; 5(3). PMID: 27141367    Free PMC article.
Immunomediated Pan-cancer Regulation Networks are Dominant Fingerprints After Treatment of Cell Lines with Demethylation.
Mariama El Baroudi, Caterina Cinti, Enrico Capobianco.
Cancer Inform, 2016 May 06; 15. PMID: 27147816    Free PMC article.
Fascin-1 as a novel diagnostic marker of triple-negative breast cancer.
Chao-Qun Wang, Chih-Hsin Tang, +10 authors, Bi-Fei Huang.
Cancer Med, 2016 May 18; 5(8). PMID: 27184764    Free PMC article.
Racial disparities in individual breast cancer outcomes by hormone-receptor subtype, area-level socio-economic status and healthcare resources.
Tomi Akinyemiju, Justin Xavier Moore, +2 authors, Sean F Altekruse.
Breast Cancer Res Treat, 2016 Jun 04; 157(3). PMID: 27255533    Free PMC article.
Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo.
See-Hyoung Park, Young Min Chung, +3 authors, Mickey C-T Hu.
Oncotarget, 2016 Jun 11; 7(27). PMID: 27283899    Free PMC article.
Defining the optimal sequence for the systemic treatment of metastatic breast cancer.
J A Mestres, A B iMolins, +17 authors, P Sanchez-Rovira.
Clin Transl Oncol, 2016 Jun 18; 19(2). PMID: 27314861    Free PMC article.
Comparisons of Oncologic Outcomes between Triple-Negative Breast Cancer (TNBC) and Non-TNBC among Patients Treated with Breast-Conserving Therapy.
Sanghwa Kim, Hyung Seok Park, +3 authors, Seung Il Kim.
Yonsei Med J, 2016 Jul 13; 57(5). PMID: 27401651    Free PMC article.
Exosome-mediated delivery of miR-9 induces cancer-associated fibroblast-like properties in human breast fibroblasts.
S Baroni, S Romero-Cordoba, +8 authors, M V Iorio.
Cell Death Dis, 2016 Jul 30; 7(7). PMID: 27468688    Free PMC article.
Highly Cited.
Features of triple-negative breast cancer: Analysis of 38,813 cases from the national cancer database.
Magdalena L Plasilova, Brandon Hayse, +3 authors, Donald R Lannin.
Medicine (Baltimore), 2016 Sep 02; 95(35). PMID: 27583878    Free PMC article.
Downregulation of androgen receptor is strongly associated with diabetes in triple negative breast cancer patients.
Francesca Collina, Margherita Cerrone, +7 authors, Maurizio Di Bonito.
Am J Transl Res, 2016 Sep 21; 8(8). PMID: 27648143    Free PMC article.
Clinicopathological Features and Prognostic Factors Affecting Survival Outcomes in Isolated Locoregional Recurrence of Breast Cancer: Single-Institutional Series.
Min-Young Lee, Won Jin Chang, +8 authors, Yeon Hee Park.
PLoS One, 2016 Sep 21; 11(9). PMID: 27648567    Free PMC article.
Atlas of human diseases influenced by genetic variants with extreme allele frequency differences.
Arvis Sulovari, Yolanda H Chen, James J Hudziak, Dawei Li.
Hum Genet, 2016 Oct 05; 136(1). PMID: 27699474
The expressions of NEDD9 and E-cadherin correlate with metastasis and poor prognosis in triple-negative breast cancer patients.
Peng Li, Tingting Sun, +3 authors, Diwen Sun.
Onco Targets Ther, 2016 Oct 06; 9. PMID: 27703373    Free PMC article.
Identification of BRCA1-like triple-negative breast cancers by quantitative multiplex-ligation-dependent probe amplification (MLPA) analysis of BRCA1-associated chromosomal regions: a validation study.
Eva Gross, Harm van Tinteren, +12 authors, Esther H Lips.
BMC Cancer, 2016 Oct 21; 16(1). PMID: 27756336    Free PMC article.
Dissecting the Origin of Breast Cancer Subtype Stem Cell and the Potential Mechanism of Malignant Transformation.
Xinyi Liu, Dongfei Feng, +6 authors, Wei Jiang.
PLoS One, 2016 Oct 22; 11(10). PMID: 27768723    Free PMC article.
Evaluation of Local and Distant Recurrence Patterns in Patients with Triple-Negative Breast Cancer According to Age.
Julia C Radosa, Anne Eaton, +7 authors, Tari A King.
Ann Surg Oncol, 2016 Oct 27; 24(3). PMID: 27783163    Free PMC article.
Clinicopathological Study of Triple Negative Breast Cancers.
Gunadala Ishitha, Marie Therese Manipadam, +3 authors, Paul Mazhuvanchary Jacob.
J Clin Diagn Res, 2016 Oct 30; 10(9). PMID: 27790442    Free PMC article.
The Poly (ADP-Ribose) Polymerase Inhibitor Veliparib and Radiation Cause Significant Cell Line Dependent Metabolic Changes in Breast Cancer Cells.
Vijesh J Bhute, Yan Ma, Xiaoping Bao, Sean P Palecek.
Sci Rep, 2016 Nov 05; 6. PMID: 27811964    Free PMC article.
Predictive Ability of 18F-fluorodeoxyglucose Positron Emission Tomography/computed Tomography for Pathological Complete Response and Prognosis after Neoadjuvant Chemotherapy in Triple-negative Breast Cancer Patients.
Sachiko Kiyoto, Yoshifumi Sugawara, +4 authors, Teruhito Mochizuki.
Asia Ocean J Nucl Med Biol, 2016 Dec 03; 4(1). PMID: 27904868    Free PMC article.
Vitamin D compounds inhibit cancer stem-like cells and induce differentiation in triple negative breast cancer.
Naing Lin Shan, Joseph Wahler, +4 authors, Nanjoo Suh.
J Steroid Biochem Mol Biol, 2016 Dec 08; 173. PMID: 27923595    Free PMC article.
Pathological Characteristics of Triple-Negative Breast Cancer at Main Referral Teaching Hospital, April 2014 to April 2015, Tehran, Iran.
Alireza Abdollahi, Mehrnoosh Etemadi.
Int J Hematol Oncol Stem Cell Res, 2016 Dec 09; 10(4). PMID: 27928473    Free PMC article.
Triple Negative Breast Cancer: Nanosolutions for a Big Challenge.
Tânia Filipa S Mendes, Leon D Kluskens, Lígia Raquel Rodrigues.
Adv Sci (Weinh), 2015 Jul 17; 2(11). PMID: 27980912    Free PMC article.
The different outcomes between breast-conserving surgery and mastectomy in triple-negative breast cancer: a population-based study from the SEER 18 database.
Qing-Xia Chen, Xiao-Xiao Wang, +4 authors, Zhi-Ming Shao.
Oncotarget, 2016 Dec 22; 8(3). PMID: 27999201    Free PMC article.
Distinctions in Breast Tumor Recurrence Patterns Post-Therapy among Racially Distinct Populations.
Nikita Wright, Jun Xia, +11 authors, Ritu Aneja.
PLoS One, 2017 Jan 14; 12(1). PMID: 28085947    Free PMC article.
MiRNAs Predict the Prognosis of Patients with Triple Negative Breast Cancer: A Meta-Analysis.
Yanli Liu, Yuchao Zhang, +8 authors, Liting Jia.
PLoS One, 2017 Jan 14; 12(1). PMID: 28085956    Free PMC article.
Stress-induced EGF receptor signaling through STAT3 and tumor progression in triple-negative breast cancer.
Nikolas Balanis, Cathleen R Carlin.
Mol Cell Endocrinol, 2017 Jan 16; 451. PMID: 28088463    Free PMC article.
Epigenetic basis of cancer health disparities: Looking beyond genetic differences.
Aamir Ahmad, Shafquat Azim, +5 authors, Ajay P Singh.
Biochim Biophys Acta Rev Cancer, 2017 Jan 22; 1868(1). PMID: 28108348    Free PMC article.
Body mass index modifies the relationship between γ-H2AX, a DNA damage biomarker, and pathological complete response in triple-negative breast cancer.
Maddalena Barba, Patrizia Vici, +15 authors, Marcello Maugeri-Saccà.
BMC Cancer, 2017 Feb 09; 17(1). PMID: 28166748    Free PMC article.
Immunohistochemical characteristics of basal-like breast cancer.
Anna M Badowska-Kozakiewicz, Michał P Budzik.
Contemp Oncol (Pozn), 2017 Feb 28; 20(6). PMID: 28239279    Free PMC article.
AR Signaling in Breast Cancer.
Bilal Rahim, Ruth O'Regan.
Cancers (Basel), 2017 Mar 02; 9(3). PMID: 28245550    Free PMC article.
Nanoparticle-linked antagonist for leptin signaling inhibition in breast cancer.
Tia Harmon, Adriana Harbuzariu, +4 authors, Ruben R Gonzalez-Perez.
World J Clin Oncol, 2017 Mar 02; 8(1). PMID: 28246585    Free PMC article.
Resistin potentiates chemoresistance and stemness of breast cancer cells: Implications for racially disparate therapeutic outcomes.
Sachin K Deshmukh, Sanjeev K Srivastava, +7 authors, Seema Singh.
Cancer Lett, 2017 Mar 18; 396. PMID: 28302531    Free PMC article.
Epidemiologic and clinicopathologic evaluation of patients with breast cancer referred to Ghaem Hospital from 2005 to 2014.
S Kadkhodayan, F Homaee Shandiz.
J Med Life, 2015 Jan 01; 8(Spec Iss 3). PMID: 28316688    Free PMC article.
Activation of the CRABPII/RAR pathway by curcumin induces retinoic acid mediated apoptosis in retinoic acid resistant breast cancer cells.
Padmamalini Thulasiraman, Galen Garriga, +2 authors, Imran Q Mohiuddin.
Oncol Rep, 2017 Mar 30; 37(4). PMID: 28350049    Free PMC article.
Targeted therapies in breast cancer: New challenges to fight against resistance.
Viviana Masoud, Gilles Pagès.
World J Clin Oncol, 2017 Apr 26; 8(2). PMID: 28439493    Free PMC article.
Triple negative breast cancer: the kiss of death.
Adriana-Andreea Jitariu, Anca Maria Cîmpean, Domenico Ribatti, Marius Raica.
Oncotarget, 2017 Apr 27; 8(28). PMID: 28445140    Free PMC article.
Highly Cited. Review.
Annexin A3 as a Prognostic Biomarker for Breast Cancer: A Retrospective Study.
Tao Zhou, Yong Li, +3 authors, Jiajie Shi.
Biomed Res Int, 2017 May 13; 2017. PMID: 28497041    Free PMC article.
MicroRNA-211-5p suppresses tumour cell proliferation, invasion, migration and metastasis in triple-negative breast cancer by directly targeting SETBP1.
Liang-Liang Chen, Zhou-Jing Zhang, Zhan-Bo Yi, Jian-Jun Li.
Br J Cancer, 2017 Jun 02; 117(1). PMID: 28571042    Free PMC article.
Pubertal development in girls by breast cancer family history: the LEGACY girls cohort.
Mary Beth Terry, Theresa H M Keegan, +11 authors, Esther M John.
Breast Cancer Res, 2017 Jun 10; 19(1). PMID: 28595647    Free PMC article.
Racial disparities in survival outcomes by breast tumor subtype among African American women in Memphis, Tennessee.
Gregory Vidal, Zoran Bursac, +2 authors, Athena Starlard-Davenport.
Cancer Med, 2017 Jun 15; 6(7). PMID: 28612435    Free PMC article.
Prevalence of Triple-Negative Breast Cancer in India: Systematic Review and Meta-Analysis.
Gurprataap S Sandhu, Sebhat Erqou, Heidi Patterson, Aju Mathew.
J Glob Oncol, 2017 Jul 19; 2(6). PMID: 28717728    Free PMC article.
Body mass index mediates the prognostic significance of circulating tumor cells in inflammatory breast cancer.
Oluwadamilola M Fayanju, Carolyn S Hall, +6 authors, Anthony Lucci.
Am J Surg, 2017 Jul 20; 214(4). PMID: 28720217    Free PMC article.
Inhibition of basal-like breast cancer growth by FTY720 in combination with epidermal growth factor receptor kinase blockade.
Janet L Martin, Sohel M Julovi, +3 authors, Robert C Baxter.
Breast Cancer Res, 2017 Aug 06; 19(1). PMID: 28778177    Free PMC article.
MicroRNA signature in the chemoprevention of functionally-enriched stem and progenitor pools (FESPP) by Active Hexose Correlated Compound (AHCC).
Émilie A Graham, Jean-François Mallet, +3 authors, Chantal Matar.
Cancer Biol Ther, 2017 Sep 09; 18(10). PMID: 28886271    Free PMC article.
Kaiso is highly expressed in TNBC tissues of women of African ancestry compared to Caucasian women.
Blessing I Bassey-Archibong, Shawn M Hercules, +9 authors, Juliet M Daniel.
Cancer Causes Control, 2017 Sep 10; 28(11). PMID: 28887687    Free PMC article.
Clinical Characteristics in Patients with Triple Negative Breast Cancer.
Janet Yeh, Jennifer Chun, +6 authors, Freya Schnabel.
Int J Breast Cancer, 2017 Sep 16; 2017. PMID: 28912973    Free PMC article.
Microarray-based SNP genotyping to identify genetic risk factors of triple-negative breast cancer (TNBC) in South Indian population.
M Aravind Kumar, Vineeta Singh, +2 authors, M Lakshmi Narasu.
Mol Cell Biochem, 2017 Sep 18; 442(1-2). PMID: 28918577
Identification of a HLA-A*0201-restricted immunogenic epitope from the universal tumor antigen DEPDC1.
Anna Tosi, Silvia Dalla Santa, +6 authors, Antonio Rosato.
Oncoimmunology, 2017 Sep 19; 6(8). PMID: 28919988    Free PMC article.
Efficacy and Safety of Vinorelbine Plus Cisplatin vs. Gemcitabine Plus Cisplatin for Treatment of Metastatic Triple-Negative Breast Cancer After Failure with Anthracyclines and Taxanes.
Junbin Wang, Rongsheng Zheng, +3 authors, Weiyan Zou.
Med Sci Monit, 2017 Sep 29; 23. PMID: 28957036    Free PMC article.
Targeted exome sequencing of Korean triple-negative breast cancer reveals homozygous deletions associated with poor prognosis of adjuvant chemotherapy-treated patients.
Hae Min Jeong, Ryong Nam Kim, +13 authors, Young Kee Shin.
Oncotarget, 2017 Oct 06; 8(37). PMID: 28977883    Free PMC article.
GABARAPL1 acts as a potential marker and promotes tumor proliferation and metastasis in triple negative breast cancer.
Li Ran, Tao Hong, +3 authors, Gebo Wen.
Oncotarget, 2017 Nov 02; 8(43). PMID: 29088804    Free PMC article.
Treatment of triple-negative breast cancer with Chinese herbal medicine: A prospective cohort study protocol.
Hui Meng, Nan Peng, +4 authors, Xiaomin Wang.
Medicine (Baltimore), 2017 Nov 03; 96(44). PMID: 29095272    Free PMC article.
Therapy response testing of breast cancer in a 3D high-throughput perfused microfluidic platform.
Henriette L Lanz, Anthony Saleh, +9 authors, Liewei Wang.
BMC Cancer, 2017 Nov 04; 17(1). PMID: 29096610    Free PMC article.
EGFR conjunct FSCN1 as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer.
Chao-Qun Wang, Yang Li, +10 authors, Xiaoni Li.
Sci Rep, 2017 Nov 17; 7(1). PMID: 29142206    Free PMC article.
PRDM14 directly interacts with heat shock proteins HSP90α and glucose-regulated protein 78.
Chiharu Moriya, Hiroaki Taniguchi, +3 authors, Kohzoh Imai.
Cancer Sci, 2017 Nov 28; 109(2). PMID: 29178343    Free PMC article.
Breast Cancer in Ghana: Demonstrating the Need for Population-Based Cancer Registries in Low- and Middle-Income Countries.
Abigail S Thomas, Kelley M Kidwell, +6 authors, Sofia D Merajver.
J Glob Oncol, 2017 Dec 16; 3(6). PMID: 29244986    Free PMC article.
Clinical and pathological factors influencing survival in a large cohort of triple-negative breast cancer patients.
Silvana Anna Maria Urru, Silvano Gallus, +25 authors, Sandra Orrù.
BMC Cancer, 2018 Jan 10; 18(1). PMID: 29310602    Free PMC article.
Fundamentals of siRNA and miRNA therapeutics and a review of targeted nanoparticle delivery systems in breast cancer.
Tamkin Ahmadzada, Glen Reid, David R McKenzie.
Biophys Rev, 2018 Jan 13; 10(1). PMID: 29327101    Free PMC article.
PD-L1 Expression in TNBC: A Predictive Biomarker of Response to Neoadjuvant Chemotherapy?
Bruna Cerbelli, Angelina Pernazza, +10 authors, Leopoldo Costarelli.
Biomed Res Int, 2018 Feb 02; 2017. PMID: 29387716    Free PMC article.
Barriers to early presentation of breast cancer among women in Soweto, South Africa.
Maureen Joffe, Oluwatosin Ayeni, +6 authors, Herbert Cubasch.
PLoS One, 2018 Feb 03; 13(2). PMID: 29394271    Free PMC article.
Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase.
Praveena S Thiagarajan, Maksim Sinyuk, +19 authors, Justin D Lathia.
Nat Commun, 2018 Feb 10; 9(1). PMID: 29422613    Free PMC article.
Breast cancer in Ethiopia: evidence for geographic difference in the distribution of molecular subtypes in Africa.
Endale Hadgu, Daniel Seifu, +7 authors, Mats G Karlsson.
BMC Womens Health, 2018 Feb 16; 18(1). PMID: 29444670    Free PMC article.
Differences in breast cancer incidence among young women aged 20-49 years by stage and tumor characteristics, age, race, and ethnicity, 2004-2013.
Meredith L Shoemaker, Mary C White, +2 authors, Isabelle Romieu.
Breast Cancer Res Treat, 2018 Feb 16; 169(3). PMID: 29445940    Free PMC article.
Morphometric analysis of a triple negative breast cancer cell line in hydrogel and monolayer culture environments.
Manasi P Jogalekar, Elba E Serrano.
PeerJ, 2018 Feb 24; 6. PMID: 29473000    Free PMC article.
Functional miRNAs in breast cancer drug resistance.
Weizi Hu, Chunli Tan, +3 authors, Jinhai Tang.
Onco Targets Ther, 2018 Mar 30; 11. PMID: 29593419    Free PMC article.
MCP-1 is overexpressed in triple-negative breast cancers and drives cancer invasiveness and metastasis.
Pranabananda Dutta, Marianna Sarkissyan, +2 authors, Jaydutt V Vadgama.
Breast Cancer Res Treat, 2018 Mar 30; 170(3). PMID: 29594759    Free PMC article.
Triple Negative Breast Cancer Depends on Sphingosine Kinase 1 (SphK1)/Sphingosine-1-Phosphate (S1P)/Sphingosine 1-Phosphate Receptor 3 (S1PR3)/Notch Signaling for Metastasis.
Shushu Wang, Yueyang Liang, +2 authors, Yi Zhang.
Med Sci Monit, 2018 Apr 02; 24. PMID: 29605826    Free PMC article.
CLR 125 Auger Electrons for the Targeted Radiotherapy of Triple-Negative Breast Cancer.
Joseph Grudzinski, Ian Marsh, +8 authors, Bryan Bednarz.
Cancer Biother Radiopharm, 2018 Apr 12; 33(3). PMID: 29641256    Free PMC article.
Prognostic Significance of Reduction in Ki67 Index After Neoadjuvant Chemotherapy in Patients With Breast Cancer in Kerman Between 2009 And 2014.
Vahid Moazed, Elham Jafari, +3 authors, Seyyed Amir Ben Razavi.
Iran J Pathol, 2018 May 08; 13(1). PMID: 29731798    Free PMC article.
Age distribution and outcomes in patients undergoing breast cancer resection in Saudi Arabia. A single-institute study.
Balqis Alabdulkarim, Mazen Hassanain, +2 authors, Hana Alkarji.
Saudi Med J, 2018 May 09; 39(5). PMID: 29738005    Free PMC article.
Bioassay-guided isolation of cantharidin from blister beetles and its anticancer activity through inhibition of epidermal growth factor receptor-mediated STAT3 and Akt pathways.
Jaemoo Chun, Min Kyoung Park, +2 authors, Yeong Shik Kim.
J Nat Med, 2018 Jul 26; 72(4). PMID: 30043217
Panoptic Overview of Triple-Negative Breast Cancer in Nigeria: Current Challenges and Promising Global Initiatives.
Nikita Wright, Padmashree Rida, +2 authors, Ritu Aneja.
J Glob Oncol, 2018 Aug 08; 4. PMID: 30085829    Free PMC article.
Triple-Negative Breast Cancer Risk Genes Identified by Multigene Hereditary Cancer Panel Testing.
Hermela Shimelis, Holly LaDuca, +26 authors, Fergus J Couch.
J Natl Cancer Inst, 2018 Aug 14; 110(8). PMID: 30099541    Free PMC article.
Highly Cited.
Fisetin Inhibited Growth and Metastasis of Triple-Negative Breast Cancer by Reversing Epithelial-to-Mesenchymal Transition via PTEN/Akt/GSK3β Signal Pathway.
Jie Li, Xia Gong, +8 authors, Hongyuan Li.
Front Pharmacol, 2018 Aug 16; 9. PMID: 30108501    Free PMC article.
A Single Institution Experience of Incorporation of Cisplatin into Adjuvant Chemotherapy for Patients With Triple-Negative Breast Cancer of Unknown BRCA Mutation Status.
Ying-Wen Su, Chia-Yen Hung, +2 authors, Po-Sheng Yang.
Clin Med Insights Oncol, 2018 Aug 29; 12. PMID: 30150877    Free PMC article.
A nomogram prediction for the survival of patients with triple negative breast cancer.
Yuxiang Lin, Fangmeng Fu, +4 authors, Chuan Wang.
Oncotarget, 2018 Sep 06; 9(63). PMID: 30181802    Free PMC article.
Association Between BRCA Status and Triple-Negative Breast Cancer: A Meta-Analysis.
Haixia Chen, Jianming Wu, +5 authors, Xianzhu Li.
Front Pharmacol, 2018 Sep 07; 9. PMID: 30186165    Free PMC article.
High Cytoplasmic CXCR4 Expression Predicts Prolonged Survival in Triple-Negative Breast Cancer Patients Treated with Adjuvant Chemotherapy.
Bobae Shim, Min-Sun Jin, +2 authors, Han Suk Ryu.
J Pathol Transl Med, 2018 Oct 03; 52(6). PMID: 30269472    Free PMC article.
New Insights into the Role of Exercise in Inhibiting mTOR Signaling in Triple-Negative Breast Cancer.
Deborah Agostini, Valentina Natalucci, +9 authors, Elena Barbieri.
Oxid Med Cell Longev, 2018 Oct 27; 2018. PMID: 30363988    Free PMC article.
Menopausal Hormone Therapy use and breast cancer risk by receptor subtypes: Results from the New South Wales Cancer Lifestyle and EvaluAtion of Risk (CLEAR) study.
Usha Salagame, Emily Banks, +2 authors, Karen Canfell.
PLoS One, 2018 Nov 08; 13(11). PMID: 30403669    Free PMC article.
Mimetic sHDL nanoparticles: A novel drug-delivery strategy to target triple-negative breast cancer.
Ton Wang, Chitra Subramanian, +7 authors, Mark S Cohen.
Surgery, 2019 Aug 03; 166(6). PMID: 31371177    Free PMC article.
Comparative Proteome Analysis of Breast Cancer Tissues Highlights the Importance of Glycerol-3-phosphate Dehydrogenase 1 and Monoacylglycerol Lipase in Breast Cancer Metabolism.
Kubra Karaosmanoglu Yoneten, Murat Kasap, +3 authors, Nihat Zafer Utkan.
Cancer Genomics Proteomics, 2019 Aug 31; 16(5). PMID: 31467232    Free PMC article.
A thiosemicarbazone derivative induces triple negative breast cancer cell apoptosis: possible role of miRNA-125a-5p and miRNA-181a-5p.
Rania El Majzoub, Mohammad Fayyad-Kazan, +7 authors, Bassam Badran.
Genes Genomics, 2019 Sep 22; 41(12). PMID: 31541355
Eupalinolide J Suppresses the Growth of Triple-Negative Breast Cancer Cells via Targeting STAT3 Signaling Pathway.
Chenghua Lou, Yan Chen, +2 authors, Huajun Zhao.
Front Pharmacol, 2019 Oct 15; 10. PMID: 31607920    Free PMC article.
Expression of the BAD pathway is a marker of triple-negative status and poor outcome.
Bernadette M Boac, Forough Abbasi, +18 authors, Douglas C Marchion.
Sci Rep, 2019 Nov 27; 9(1). PMID: 31767884    Free PMC article.
Strong association of fascin expression with triple negative breast cancer and basal-like phenotype in African-American women.
Ashwini K Esnakula, Luisel Ricks-Santi, +6 authors, Tammey J Naab.
J Clin Pathol, 2013 Aug 30; 67(2). PMID: 23986556    Free PMC article.
Development and Validation of Nomograms for Predicting the Prognosis of Triple-Negative Breast Cancer Patients Based on 379 Chinese Patients.
Hao Shi, Xiao-Hui Wang, Jun-Wei Gu, Gui-Long Guo.
Cancer Manag Res, 2020 Jan 11; 11. PMID: 31920392    Free PMC article.
MicroRNAs Involved in Carcinogenesis, Prognosis, Therapeutic Resistance and Applications in Human Triple-Negative Breast Cancer.
Lei Ding, Huan Gu, +6 authors, Qinghua Cui.
Cells, 2019 Nov 27; 8(12). PMID: 31766744    Free PMC article.
Comparison of Clinico-Pathological Presentations of Triple-Negative versus Triple-Positive and HER2 Iraqi Breast Cancer Patients.
Nada A S Alwan, Furat N Tawfeeq.
Open Access Maced J Med Sci, 2020 Feb 06; 7(21). PMID: 32010372    Free PMC article.
Double-positive in triple-negative? How significant is basal cytokeratin expression in breast cancer?
Anusree Majumder, Rajat Jagani, Atoshi Basu.
Med J Armed Forces India, 2020 Feb 06; 76(1). PMID: 32020971    Free PMC article.
The miRNA-449 family mediates doxorubicin resistance in triple-negative breast cancer by regulating cell cycle factors.
Eduardo Tormo, Sandra Ballester, +11 authors, Pilar Eroles.
Sci Rep, 2019 Mar 31; 9(1). PMID: 30926829    Free PMC article.
Estradiol induces BDNF/TrkB signaling in triple-negative breast cancer to promote brain metastases.
Maria J Contreras-Zárate, Nicole L Day, +5 authors, Diana M Cittelly.
Oncogene, 2019 Feb 24; 38(24). PMID: 30796353    Free PMC article.
Transcriptional positive cofactor 4 promotes breast cancer proliferation and metastasis through c-Myc mediated Warburg effect.
Peng Luo, Chi Zhang, +9 authors, Chunmeng Shi.
Cell Commun Signal, 2019 Apr 18; 17(1). PMID: 30992017    Free PMC article.
Strictinin, a novel ROR1-inhibitor, represses triple negative breast cancer survival and migration via modulation of PI3K/AKT/GSK3ß activity.
Norman Fultang, Abhinav Illendula, +5 authors, Bela Peethambaran.
PLoS One, 2019 Jun 01; 14(5). PMID: 31150511    Free PMC article.
The identification of a TNBC liver metastasis gene signature by sequential CTC-xenograft modeling.
Monika Vishnoi, Nikki Haowen Liu, +4 authors, Dario Marchetti.
Mol Oncol, 2019 Jun 20; 13(9). PMID: 31216110    Free PMC article.
A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy.
Ronan P McLaughlin, Jichao He, +6 authors, Bob van de Water.
Breast Cancer Res, 2019 Jul 03; 21(1). PMID: 31262335    Free PMC article.
A Sesquiterpenoid from Farfarae Flos Induces Apoptosis of MDA-MB-231 Human Breast Cancer Cells through Inhibition of JAK-STAT3 Signaling.
Hyeri Jang, Hyejin Ko, Kwangho Song, Yeong Shik Kim.
Biomolecules, 2019 Jul 25; 9(7). PMID: 31337063    Free PMC article.
Berberine Impairs the Survival of Triple Negative Breast Cancer Cells: Cellular and Molecular Analyses.
Lamyae El Khalki, Virginie Maire, Thierry Dubois, Abdelmajid Zyad.
Molecules, 2020 Jan 30; 25(3). PMID: 31991634    Free PMC article.
GP130 Cytokines in Breast Cancer and Bone.
Tolu Omokehinde, Rachelle W Johnson.
Cancers (Basel), 2020 Feb 07; 12(2). PMID: 32023849    Free PMC article.
Molecular Mechanisms of PALB2 Function and Its Role in Breast Cancer Management.
Shijie Wu, Jiaojiao Zhou, +5 authors, Yiding Chen.
Front Oncol, 2020 Mar 19; 10. PMID: 32185139    Free PMC article.
NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer.
Ge Qin, Xin Wang, +18 authors, Wuguo Deng.
Nat Commun, 2020 Apr 05; 11(1). PMID: 32245950    Free PMC article.
Knockdown of lncRNA PCAT6 Enhances Radiosensitivity in Triple-Negative Breast Cancer Cells by Regulating miR-185-5p/TPD52 Axis.
Rui Shi, Peng Wu, +2 authors, Longjiao Cong.
Onco Targets Ther, 2020 Apr 21; 13. PMID: 32308433    Free PMC article.
LNK promotes the growth and metastasis of triple negative breast cancer via activating JAK/STAT3 and ERK1/2 pathway.
Jianxin Lv, Wei Yu, +4 authors, Chenfei Wang.
Cancer Cell Int, 2020 Apr 24; 20. PMID: 32322171    Free PMC article.
Outcomes of ovarian stimulation and fertility preservation in breast cancer patients with different hormonal receptor profiles.
Jacques Balayla, Togas Tulandi, +4 authors, Alexander Volodarsky-Perel.
J Assist Reprod Genet, 2020 Mar 08; 37(4). PMID: 32144524    Free PMC article.
Narrowing the focus: Therapeutic cell surface targets for refractory triple-negative breast cancer.
Narges K Tafreshi, David L Morse, Marie Catherine Lee.
World J Clin Oncol, 2020 May 02; 11(4). PMID: 32355639    Free PMC article.
Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy.
Renee C Geck, Jackson R Foley, +3 authors, Alex Toker.
J Biol Chem, 2020 Mar 07; 295(19). PMID: 32139506    Free PMC article.
Inhibitory Effects of Tangeretin, A Citrus Peel-Derived Flavonoid, on Breast Cancer Stem Cell Formation through Suppression of Stat3 Signaling.
Yu-Chan Ko, Hack Sun Choi, +4 authors, Dong-Sun Lee.
Molecules, 2020 Jun 07; 25(11). PMID: 32503228    Free PMC article.
CinéBreast-factors influencing the time to first metastatic recurrence in breast cancer: Analysis of real-life data from the French ESME MBC database.
P Gougis, M Carton, +20 authors, C Le Tourneau.
Breast, 2019 Nov 02; 49. PMID: 31675683    Free PMC article.
Breast MRI texture analysis for prediction of BRCA-associated genetic risk.
Georgia Vasileiou, Maria J Costa, +14 authors, Matthias Hammon.
BMC Med Imaging, 2020 Jul 31; 20(1). PMID: 32727387    Free PMC article.
A Six-Epithelial-Mesenchymal Transition Gene Signature May Predict Metastasis of Triple-Negative Breast Cancer.
Li Yuan Wei, Xiao Jun Zhang, +4 authors, Jin Nan Gao.
Onco Targets Ther, 2020 Aug 06; 13. PMID: 32753890    Free PMC article.
Understanding breast cancer disparities-a multi-scale challenge.
Hannah E Hill, William P Schiemann, Vinay Varadan.
Ann Transl Med, 2020 Aug 15; 8(14). PMID: 32793750    Free PMC article.
Distinguishing metastatic triple-negative breast cancer from nonmetastatic breast cancer using second harmonic generation imaging and resonance Raman spectroscopy.
Ethan Bendau, Jason Smith, +6 authors, Lingyan Shi.
J Biophotonics, 2020 Mar 29; 13(7). PMID: 32219996    Free PMC article.
WNT signaling pathway regulator-FRAT2 affects oncogenesis and prognosis of basal-like breast cancer.
Yao Zhou, Can Li, +5 authors, Taiyuan Li.
J Thorac Dis, 2020 Aug 18; 12(7). PMID: 32802426    Free PMC article.
Overview of the genetic basis toward early detection of breast cancer.
Sumadee De Silva, Kamani Hemamala Tennekoon, Eric Hamilton Karunanayake.
Breast Cancer (Dove Med Press), 2019 Feb 06; 11. PMID: 30718964    Free PMC article.
Triple-negative breast cancer: the reality in Chile and in Latin America.
Christian Caglevic, Jaime Anabalón, +6 authors, Mauricio Mahave.
Ecancermedicalscience, 2019 Feb 23; 13. PMID: 30792810    Free PMC article.
Precision medicine for locally advanced breast cancer: frontiers and challenges in Latin America.
Joseph A Pinto, César H Saravia, +10 authors, Henry L Gómez.
Ecancermedicalscience, 2019 Feb 23; 13. PMID: 30792813    Free PMC article.
The effect of neoadjuvant platinum-based chemotherapy in BRCA mutated triple negative breast cancers -systematic review and meta-analysis.
Olga Caramelo, Cristina Silva, +2 authors, Teresa Almeida-Santos.
Hered Cancer Clin Pract, 2019 Apr 10; 17. PMID: 30962858    Free PMC article.
Clinical and Cyto-Morphological Characterization of Triple Negative Breast Cancer.
Chayanika Kala, Mohd Athar, +3 authors, Amitabh Satsangi.
J Cytol, 2019 Apr 18; 36(2). PMID: 30992642    Free PMC article.
Correlation of CD8+ Expression, Foxp3+ Expression, and CD8+/Foxp3+ Ratio with Triple Negative Breast Cancer Stage in Sanglah General Hospital.
I Wayan Sudarsa, Dewa Gede Subawa, Putu Anda Tusta Adiputra, Ida Bagus Tjakra Wibawa Manuaba.
Open Access Maced J Med Sci, 2019 Jun 19; 7(10). PMID: 31210806    Free PMC article.
Perspectives on Triple-Negative Breast Cancer: Current Treatment Strategies, Unmet Needs, and Potential Targets for Future Therapies.
Gagan K Gupta, Amber L Collier, +13 authors, Amy H Tang.
Cancers (Basel), 2020 Aug 28; 12(9). PMID: 32846967    Free PMC article.
The Survival Outcomes of T1aN0M0 Triple-Negative Breast Cancer With Adjuvant Chemotherapy.
Wen-Fen Fu, Qing-Xia Chen, +2 authors, Chuan-Gui Song.
Front Oncol, 2020 Oct 27; 10. PMID: 33102205    Free PMC article.
Downregulated METTL14 Expression Correlates with Breast Cancer Tumor Grade and Molecular Classification.
Xiao-Fang Dong, Yan Wang, +5 authors, Chao-Qun Wang.
Biomed Res Int, 2020 Nov 03; 2020. PMID: 33134390    Free PMC article.
Thioguanine Induces Apoptosis in Triple-Negative Breast Cancer by Regulating PI3K-AKT Pathway.
Daoyu Zhang, Xinglan An, +7 authors, Ziyi Li.
Front Oncol, 2020 Nov 17; 10. PMID: 33194583    Free PMC article.
Single-nucleotide polymorphisms and mRNA expression of CYP1B1 influence treatment response in triple negative breast cancer patients undergoing chemotherapy.
Ahmad Aizat Abdul Aziz, Md Salzihan Md Salleh, +5 authors, Ravindran Ankathil.
J Genet, 2018 Dec 18; 97(5). PMID: 30555068
Development and validation of a prognostic nomogram for patients with triple-negative breast cancer with histology of infiltrating duct carcinoma.
Na Jing, Ming-Wei Ma, +7 authors, Hai-Xia Jia.
Ann Transl Med, 2020 Dec 15; 8(21). PMID: 33313192    Free PMC article.
Combined High Resistin and EGFR Expression Predicts a Poor Prognosis in Breast Cancer.
Yue Zeng, Chih-Hsin Tang, +7 authors, Li-Song Teng.
Biomed Res Int, 2020 Dec 15; 2020. PMID: 33313320    Free PMC article.
Breast Trauma and Triple-Negative Hemorrhagic Cystic Carcinoma: Management and Treatment.
Maria Cotesta, Oreste Claudio Buonomo, +10 authors, Marco Pellicciaro.
Am J Case Rep, 2020 Dec 15; 21. PMID: 33311426    Free PMC article.
Gene Expression Alterations Associated with Oleuropein-Induced Antiproliferative Effects and S-Phase Cell Cycle Arrest in Triple-Negative Breast Cancer Cells.
Samia S Messeha, Najla O Zarmouh, Abrar Asiri, Karam F A Soliman.
Nutrients, 2020 Dec 11; 12(12). PMID: 33297339    Free PMC article.
Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention.
Esmee Koedoot, Eline van Steijn, +5 authors, Bob van de Water.
J Exp Clin Cancer Res, 2021 Mar 03; 40(1). PMID: 33648524    Free PMC article.
Celastrol attenuates the inflammatory response by inhibiting IL‑1β expression in triple‑negative breast cancer cells.
Daeun You, Yisun Jeong, +5 authors, Sangmin Kim.
Oncol Rep, 2021 Apr 14; 45(6). PMID: 33846813    Free PMC article.
Antitumor Activity of Pulvomycin via Targeting Activated-STAT3 Signaling in Docetaxel-Resistant Triple-Negative Breast Cancer Cells.
Woong Sub Byun, Eun Seo Bae, +3 authors, Sang Kook Lee.
Biomedicines, 2021 May 01; 9(4). PMID: 33920736    Free PMC article.
Glucocorticoid Receptor: A Multifaceted Actor in Breast Cancer.
Lara Malik Noureddine, Olivier Trédan, +3 authors, Coralie Poulard.
Int J Mol Sci, 2021 May 01; 22(9). PMID: 33923160    Free PMC article.
Prognostic Models for Nonmetastatic Triple-Negative Breast Cancer Based on the Pretreatment Serum Tumor Markers with Machine Learning.
Huihui Chen, Shijie Wu, +6 authors, Yiding Chen.
J Oncol, 2021 Jun 01; 2021. PMID: 34054955    Free PMC article.
Triple-negative breast cancer: promising prognostic biomarkers currently in development.
Jasmine Sukumar, Kelly Gast, +2 authors, Nicole Williams.
Expert Rev Anticancer Ther, 2020 Nov 18; 21(2). PMID: 33198517    Free PMC article.