Journal Article
. 2012 Dec; 381(9869):805-16.
doi: 10.1016/S0140-6736(12)61963-1.

Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial

Christina Davies 1 Hongchao Pan  Jon Godwin  Richard Gray  Rodrigo Arriagada  Vinod Raina  Mirta Abraham  Victor Hugo Medeiros Alencar  Atef Badran  Xavier Bonfill  Joan Bradbury  Michael Clarke  Rory Collins  Susan R Davis  Antonella Delmestri  John F Forbes  Peiman Haddad  Ming-Feng Hou  Moshe Inbar  Hussein Khaled  Joanna Kielanowska  Wing-Hong Kwan  Beela S Mathew  Indraneel Mittra  Bettina Müller  Antonio Nicolucci  Octavio Peralta  Fany Pernas  Lubos Petruzelka  Tadeusz Pienkowski  Ramachandran Radhika  Balakrishnan Rajan  Maryna T Rubach  Sera Tort  Gerard Urrútia  Miriam Valentini  Yaochen Wang  Richard Peto  Adjuvant Tamoxifen: Longer Against Shorter (ATLAS) Collaborative Group  
Affiliations
  • PMID: 23219286
  •     19 References
  •     511 citations

Abstract

Background: For women with oestrogen receptor (ER)-positive early breast cancer, treatment with tamoxifen for 5 years substantially reduces the breast cancer mortality rate throughout the first 15 years after diagnosis. We aimed to assess the further effects of continuing tamoxifen to 10 years instead of stopping at 5 years.

Methods: In the worldwide Adjuvant Tamoxifen: Longer Against Shorter (ATLAS) trial, 12,894 women with early breast cancer who had completed 5 years of treatment with tamoxifen were randomly allocated to continue tamoxifen to 10 years or stop at 5 years (open control). Allocation (1:1) was by central computer, using minimisation. After entry (between 1996 and 2005), yearly follow-up forms recorded any recurrence, second cancer, hospital admission, or death. We report effects on breast cancer outcomes among the 6846 women with ER-positive disease, and side-effects among all women (with positive, negative, or unknown ER status). Long-term follow-up still continues. This study is registered, number ISRCTN19652633.

Findings: Among women with ER-positive disease, allocation to continue tamoxifen reduced the risk of breast cancer recurrence (617 recurrences in 3428 women allocated to continue vs 711 in 3418 controls, p=0·002), reduced breast cancer mortality (331 deaths vs 397 deaths, p=0·01), and reduced overall mortality (639 deaths vs 722 deaths, p=0·01). The reductions in adverse breast cancer outcomes appeared to be less extreme before than after year 10 (recurrence rate ratio [RR] 0·90 [95% CI 0·79–1·02] during years 5–9 and 0·75 [0·62–0·90] in later years; breast cancer mortality RR 0·97 [0·79–1·18] during years 5–9 and 0·71 [0·58–0·88] in later years). The cumulative risk of recurrence during years 5–14 was 21·4% for women allocated to continue versus 25·1% for controls; breast cancer mortality during years 5–14 was 12·2% for women allocated to continue versus 15·0% for controls (absolute mortality reduction 2·8%). Treatment allocation seemed to have no effect on breast cancer outcome among 1248 women with ER-negative disease, and an intermediate effect among 4800 women with unknown ER status. Among all 12,894 women, mortality without recurrence from causes other than breast cancer was little affected (691 deaths without recurrence in 6454 women allocated to continue versus 679 deaths in 6440 controls; RR 0·99 [0·89–1·10]; p=0·84). For the incidence (hospitalisation or death) rates of specific diseases, RRs were as follows: pulmonary embolus 1·87 (95% CI 1·13–3·07, p=0·01 [including 0·2% mortality in both treatment groups]), stroke 1·06 (0·83–1·36), ischaemic heart disease 0·76 (0·60–0·95, p=0·02), and endometrial cancer 1·74 (1·30–2·34, p=0·0002). The cumulative risk of endometrial cancer during years 5–14 was 3·1% (mortality 0·4%) for women allocated to continue versus 1·6% (mortality 0·2%) for controls (absolute mortality increase 0·2%).

Interpretation: For women with ER-positive disease, continuing tamoxifen to 10 years rather than stopping at 5 years produces a further reduction in recurrence and mortality, particularly after year 10. These results, taken together with results from previous trials of 5 years of tamoxifen treatment versus none, suggest that 10 years of tamoxifen treatment can approximately halve breast cancer mortality during the second decade after diagnosis.

Funding: Cancer Research UK, UK Medical Research Council, AstraZeneca UK, US Army, EU-Biomed.

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Identification of gene regulation patterns underlying both oestrogen- and tamoxifen-stimulated cell growth through global gene expression profiling in breast cancer cells.
Ping Fan, Heather E Cunliffe, +4 authors, V Craig Jordan.
Eur J Cancer, 2014 Sep 13; 50(16). PMID: 25212499    Free PMC article.
Effects of switching from anastrozole to letrozole, due to reimbursement policy, on the outcome of breast cancer therapy.
Potchavit Aphinives, Damnern Vachirodom, +2 authors, Ongart Somintara.
Breast Cancer (Dove Med Press), 2014 Sep 25; 6. PMID: 25249759    Free PMC article.
Pharmacological relevance of endoxifen in a laboratory simulation of breast cancer in postmenopausal patients.
Philipp Y Maximov, Russell E McDaniel, +4 authors, V Craig Jordan.
J Natl Cancer Inst, 2014 Sep 27; 106(10). PMID: 25258390    Free PMC article.
Linking estrogen-induced apoptosis with decreases in mortality following long-term adjuvant tamoxifen therapy.
V Craig Jordan.
J Natl Cancer Inst, 2014 Oct 02; 106(11). PMID: 25269699    Free PMC article.
Genetic variants of kinase suppressors of Ras (KSR1) to predict survival in patients with ERα-positive advanced breast cancer.
L Benhaim, W Zhang, +14 authors, H J Lenz.
Pharmacogenomics J, 2014 Oct 08; 15(3). PMID: 25287073
Caring for the breast cancer survivor's health and well-being.
Petra M Casey, Stephanie S Faubion, +2 authors, Sandhya Pruthi.
World J Clin Oncol, 2014 Oct 11; 5(4). PMID: 25302171    Free PMC article.
Review.
Time dependence of biomarkers: non-proportional effects of immunohistochemical panels predicting relapse risk in early breast cancer.
J Stephen, G Murray, +13 authors, J M S Bartlett.
Br J Cancer, 2014 Oct 15; 111(12). PMID: 25314051    Free PMC article.
Breast cancer therapy planning - a novel support concept for a sequential decision making problem.
Alexander Scherrer, Ilka Schwidde, +3 authors, Karl-Heinz Küfer.
Health Care Manag Sci, 2014 Oct 16; 18(3). PMID: 25315184
Crossover effects of estrogen receptor status on breast cancer-specific hazard rates by age and race.
Yu Ren, Dalliah M Black, +7 authors, Min Yi.
PLoS One, 2014 Oct 22; 9(10). PMID: 25333877    Free PMC article.
The new biology of estrogen-induced apoptosis applied to treat and prevent breast cancer.
V Craig Jordan.
Endocr Relat Cancer, 2014 Oct 24; 22(1). PMID: 25339261    Free PMC article.
Review.
Perspectives of postmenopausal breast cancer survivors on adjuvant endocrine therapy-related symptoms.
G J van Londen, Heidi S Donovan, +7 authors, Mary Amanda Dew.
Oncol Nurs Forum, 2014 Oct 31; 41(6). PMID: 25355021    Free PMC article.
Current treatment of early breast cancer: adjuvant and neoadjuvant therapy.
Elizabeth Miller, Hee Jin Lee, +3 authors, Bora Lim.
F1000Res, 2014 Nov 18; 3. PMID: 25400908    Free PMC article.
Review.
Standard of care and controversies in the adjuvant endocrine treatment of hormone-responsive early breast cancer.
Dirk O Bauerschlag, Nicolai Maass, Christian Schem.
Breast Care (Basel), 2014 Nov 19; 9(4). PMID: 25404889    Free PMC article.
Review.
Meaningful prevention of breast cancer metastasis: candidate therapeutics, preclinical validation, and clinical trial concerns.
Alexandra S Zimmer, Patricia S Steeg.
J Mol Med (Berl), 2014 Nov 22; 93(1). PMID: 25412774    Free PMC article.
Review.
Estrogen independent gene expression defines clinically relevant subgroups of estrogen receptor positive breast cancer.
Robin M Hallett, John A Hassell.
BMC Cancer, 2014 Nov 26; 14. PMID: 25420785    Free PMC article.
Expression levels of SF3B3 correlate with prognosis and endocrine resistance in estrogen receptor-positive breast cancer.
Yesim Gökmen-Polar, Yaseswini Neelamraju, +4 authors, Sunil Badve.
Mod Pathol, 2014 Nov 29; 28(5). PMID: 25431237
Biology of breast cancer in young women.
Hatem A Azim, Ann H Partridge.
Breast Cancer Res, 2014 Dec 02; 16(4). PMID: 25436920    Free PMC article.
Highly Cited. Review.
Emerging gene-based prognostic tools in early breast cancer: First steps to personalised medicine.
Umar Wazir, Kefah Mokbel.
World J Clin Oncol, 2014 Dec 11; 5(5). PMID: 25493218    Free PMC article.
Heterogeneity in hormone-receptor status and survival outcomes among women with synchronous and metachronous bilateral breast cancers.
Zora Baretta, Olufunmilayo I Olopade, Dezheng Huo.
Breast, 2014 Dec 24; 24(2). PMID: 25534718    Free PMC article.
Unique features of young age breast cancer and its management.
Han-Byoel Lee, Wonshik Han.
J Breast Cancer, 2014 Dec 31; 17(4). PMID: 25548576    Free PMC article.
Review.
The future of breast cancer systemic therapy: the next 10 years.
Melinda L Telli, George W Sledge.
J Mol Med (Berl), 2015 Jan 09; 93(2). PMID: 25566982
Review.
Germline oncopharmacogenetics, a promising field in cancer therapy.
Chiara Pesenti, Milena Gusella, Silvia M Sirchia, Monica Miozzo.
Cell Oncol (Dordr), 2015 Jan 13; 38(1). PMID: 25573079
Review.
Current management of lesions associated with an increased risk of breast cancer.
Monica Morrow, Stuart J Schnitt, Larry Norton.
Nat Rev Clin Oncol, 2015 Jan 28; 12(4). PMID: 25622978
Review.
Unique aspects of caring for young breast cancer patients.
Raina M Ferzoco, Kathryn J Ruddy.
Curr Oncol Rep, 2015 Feb 04; 17(2). PMID: 25645111
Review.
A comparison of letrozole and anastrozole followed by letrozole in breast cancer patients.
Potchavit Aphinives, Damnern Vachirodom, +2 authors, Ongart Somintara.
Breast Cancer (Dove Med Press), 2015 Feb 06; 7. PMID: 25653555    Free PMC article.
Better contralateral breast cancer risk estimation and alternative options to contralateral prophylactic mastectomy.
Kalatu R Davies, Scott B Cantor, Abenaa M Brewster.
Int J Womens Health, 2015 Feb 14; 7. PMID: 25678823    Free PMC article.
Review.
Oncogene addiction: pathways of therapeutic response, resistance, and road maps toward a cure.
Raymond Pagliarini, Wenlin Shao, William R Sellers.
EMBO Rep, 2015 Feb 15; 16(3). PMID: 25680965    Free PMC article.
Highly Cited. Review.
A snapshot of cancer in Chile: analytical frameworks for developing a cancer policy.
Jorge Jimenez de la Jara, Gabriel Bastias, +15 authors, Gareth I Owen.
Biol Res, 2015 Mar 13; 48. PMID: 25761441    Free PMC article.
Review.
Molecular mechanisms of tamoxifen-associated endometrial cancer (Review).
Rong Hu, Leena Hilakivi-Clarke, Robert Clarke.
Oncol Lett, 2015 Mar 20; 9(4). PMID: 25788989    Free PMC article.
Timing of adjuvant surgical oophorectomy in the menstrual cycle and disease-free and overall survival in premenopausal women with operable breast cancer.
Richard R Love, Adriano V Laudico, +18 authors, David Jarjoura.
J Natl Cancer Inst, 2015 Mar 22; 107(6). PMID: 25794890    Free PMC article.
Breast cancer under age 40: a different approach.
D Ribnikar, J M Ribeiro, +6 authors, F Cardoso.
Curr Treat Options Oncol, 2015 Mar 23; 16(4). PMID: 25796377
Review.
Metastasis prevention by targeting the dormant niche.
Cyrus M Ghajar.
Nat Rev Cancer, 2015 Mar 25; 15(4). PMID: 25801619    Free PMC article.
Highly Cited. Review.
Challenges and Potential for Ovarian Preservation with SERMs.
Alison Y Ting, Brian K Petroff.
Biol Reprod, 2015 Mar 27; 92(5). PMID: 25810474    Free PMC article.
Review.
Optimal systemic therapy for early breast cancer in women: a clinical practice guideline.
A Eisen, G G Fletcher, +5 authors, members of the Early Breast Cancer Systemic Therapy Consensus Panel.
Curr Oncol, 2015 Apr 08; 22(Suppl 1). PMID: 25848340    Free PMC article.
Outcome of patients with pregnancy during or after breast cancer: a review of the recent literature.
J Raphael, M E Trudeau, K Chan.
Curr Oncol, 2015 Apr 08; 22(Suppl 1). PMID: 25848342    Free PMC article.
Review.
Adjuvant endocrine therapy for early breast cancer: a systematic review of the evidence for the 2014 Cancer Care Ontario systemic therapy guideline.
O C Freedman, G G Fletcher, +4 authors, A Eisen.
Curr Oncol, 2015 Apr 08; 22(Suppl 1). PMID: 25848344    Free PMC article.
Review.
Markers for the identification of late breast cancer recurrence.
Ivana Sestak, Jack Cuzick.
Breast Cancer Res, 2015 Apr 08; 17. PMID: 25848913    Free PMC article.
Review.
Mechanisms of endocrine resistance in breast cancer: an overview of the proposed roles of noncoding RNA.
Erin L Hayes, Joan S Lewis-Wambi.
Breast Cancer Res, 2015 Apr 08; 17. PMID: 25849966    Free PMC article.
Highly Cited. Review.
Impact of Molecular Subtype Conversion of Breast Cancers after Neoadjuvant Chemotherapy on Clinical Outcome.
Siew Kuan Lim, Moo Hyun Lee, +8 authors, Eun Sook Lee.
Cancer Res Treat, 2015 Apr 14; 48(1). PMID: 25865655    Free PMC article.
TFF3 is a valuable predictive biomarker of endocrine response in metastatic breast cancer.
Felicity E B May, Bruce R Westley.
Endocr Relat Cancer, 2015 Apr 23; 22(3). PMID: 25900183    Free PMC article.
Breast cancer survivorship: a comprehensive review of long-term medical issues and lifestyle recommendations.
Balazs I Bodai, Phillip Tuso.
Perm J, 2015 Apr 23; 19(2). PMID: 25902343    Free PMC article.
Review.
Racial/Ethnic and socioeconomic disparities in endocrine therapy adherence in breast cancer: a systematic review.
Megan C Roberts, Stephanie B Wheeler, Katherine Reeder-Hayes.
Am J Public Health, 2015 Apr 24; 105 Suppl 3. PMID: 25905855    Free PMC article.
Systematic Review.
Mechanisms of aromatase inhibitor resistance.
Cynthia X Ma, Tomás Reinert, Izabela Chmielewska, Matthew J Ellis.
Nat Rev Cancer, 2015 Apr 25; 15(5). PMID: 25907219
Highly Cited. Review.
Developing a new generation of breast cancer clinical gene expression tests.
Zuzana Kos, Torsten O Nielsen.
Breast Cancer Res, 2014 Jan 01; 16(4). PMID: 25928431    Free PMC article.
Tailoring therapies--improving the management of early breast cancer: St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2015.
A S Coates, E P Winer, +6 authors, Panel Members.
Ann Oncol, 2015 May 06; 26(8). PMID: 25939896    Free PMC article.
Highly Cited.
Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen.
Aurelia H M de Vries Schultink, Wilbert Zwart, +2 authors, Alwin D R Huitema.
Clin Pharmacokinet, 2015 May 06; 54(8). PMID: 25940823    Free PMC article.
Review.
Polymorphism at 19q13.41 Predicts Breast Cancer Survival Specifically after Endocrine Therapy.
Sofia Khan, Rainer Fagerholm, +6 authors, Heli Nevanlinna.
Clin Cancer Res, 2015 May 13; 21(18). PMID: 25964295    Free PMC article.
The introduction of generic aromatase inhibitors and treatment adherence among Medicare D enrollees.
Joan M Neuner, Sailaja Kamaraju, +6 authors, Liliana E Pezzin.
J Natl Cancer Inst, 2015 May 15; 107(8). PMID: 25971298    Free PMC article.
Endocrine therapy adherence: a cross-sectional study of factors affecting adherence and discontinuation of therapy.
E M Quinn, C Fleming, M J O'Sullivan.
Ir J Med Sci, 2015 May 15; 185(2). PMID: 25971465
Challenges in the management of advanced, ER-positive, HER2-negative breast cancer.
Christopher D Hart, Ilenia Migliaccio, +3 authors, Angelo Di Leo.
Nat Rev Clin Oncol, 2015 May 27; 12(9). PMID: 26011489
Review.
The UZ Leuven Policy for Extended Adjuvant Anti-estrogen Therapy in Women With Early Estrogen Receptor-Positive Breast Cancer.
Kathleen Van Asten, An Poppe, +4 authors, Patrick Neven.
Curr Treat Options Oncol, 2015 Jun 03; 16(7). PMID: 26031545
Review.
The molecular, cellular and clinical consequences of targeting the estrogen receptor following estrogen deprivation therapy.
Ping Fan, Philipp Y Maximov, +2 authors, V Craig Jordan.
Mol Cell Endocrinol, 2015 Jun 09; 418 Pt 3. PMID: 26052034    Free PMC article.
Review.
Clinical utility of exemestane in the treatment of breast cancer.
Giorgia Zucchini, Elena Geuna, +3 authors, Filippo Montemurro.
Int J Womens Health, 2015 Jun 13; 7. PMID: 26064072    Free PMC article.
Review.
Long-Term Follow-Up of the E1199 Phase III Trial Evaluating the Role of Taxane and Schedule in Operable Breast Cancer.
Joseph A Sparano, Fengmin Zhao, +7 authors, Nancy E Davidson.
J Clin Oncol, 2015 Jun 17; 33(21). PMID: 26077235    Free PMC article.
Depression as a predictor of adherence to adjuvant endocrine therapy (AET) in women with breast cancer: a systematic review and meta-analysis.
Brent T Mausbach, Richard B Schwab, Scott A Irwin.
Breast Cancer Res Treat, 2015 Jun 17; 152(2). PMID: 26077640    Free PMC article.
Systematic Review.
Time-varying effect and long-term survival analysis in breast cancer patients treated with neoadjuvant chemotherapy.
S Baulies, L Belin, +8 authors, F Reyal.
Br J Cancer, 2015 Jun 17; 113(1). PMID: 26079300    Free PMC article.
Fertility Preservation Success Subsequent to Concurrent Aromatase Inhibitor Treatment and Ovarian Stimulation in Women With Breast Cancer.
Kutluk Oktay, Volkan Turan, +2 authors, Fred Moy.
J Clin Oncol, 2015 Jun 24; 33(22). PMID: 26101247    Free PMC article.
Tamoxifen with ovarian function suppression versus tamoxifen alone as an adjuvant treatment for premenopausal breast cancer: a meta-analysis of published randomized controlled trials.
Shunchao Yan, Kai Li, Xin Jiao, Huawei Zou.
Onco Targets Ther, 2015 Jun 26; 8. PMID: 26109867    Free PMC article.
Application status of tamoxifen in endocrine therapy for early breast cancer.
Qiancheng Hu, Ting Luo, +3 authors, Hong Zheng.
Exp Ther Med, 2015 Jul 03; 9(6). PMID: 26136961    Free PMC article.
Joint symptoms and health-related quality of life in postmenopausal women with breast cancer who completed 5 years of anastrozole.
Hiroshi Yagata, Hiroshi Ohtsu, +6 authors, Kojiro Shimozuma.
Support Care Cancer, 2015 Jul 15; 24(2). PMID: 26153513
Navigating the Challenges of Endocrine Treatments in Premenopausal Women with ER-Positive Early Breast Cancer.
Marco Colleoni, Elisabetta Munzone.
Drugs, 2015 Jul 17; 75(12). PMID: 26177891
Review.
Clinical utility of the IHC4+C score in oestrogen receptor-positive early breast cancer: a prospective decision impact study.
B Yeo, L Zabaglo, +3 authors, M Dowsett.
Br J Cancer, 2015 Jul 17; 113(3). PMID: 26180920    Free PMC article.
Breast Cancer After Use of Estrogen Plus Progestin and Estrogen Alone: Analyses of Data From 2 Women's Health Initiative Randomized Clinical Trials.
Rowan T Chlebowski, Thomas E Rohan, +11 authors, Ross L Prentice.
JAMA Oncol, 2015 Jul 17; 1(3). PMID: 26181174    Free PMC article.
How individual participant data meta-analyses have influenced trial design, conduct, and analysis.
Jayne F Tierney, Jean-Pierre Pignon, +5 authors, Cochrane IPD Meta-analysis Methods Group.
J Clin Epidemiol, 2015 Jul 19; 68(11). PMID: 26186982    Free PMC article.
St. Gallen/Vienna 2015: A Brief Summary of the Consensus Discussion.
Michael Gnant, Christoph Thomssen, Nadia Harbeck.
Breast Care (Basel), 2015 Jul 22; 10(2). PMID: 26195941    Free PMC article.
Review.
Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?
Wilbert Zwart, Huub Terra, Sabine C Linn, Sanne B Schagen.
Nat Rev Clin Oncol, 2015 Jul 22; 12(10). PMID: 26196252
Review.
Adjuvant Endocrine Therapy and Bone Health in Breast Cancer.
Gregory A Clines, Palak Choksi, Catherine Van Poznak.
Curr Osteoporos Rep, 2015 Jul 26; 13(5). PMID: 26209043
Review.
Optimal approach in early breast cancer: Adjuvant and neoadjuvant treatment.
J Ribeiro, B Sousa, F Cardoso.
EJC Suppl, 2013 Sep 01; 11(2). PMID: 26217109    Free PMC article.
Review.
Adjuvant endocrine therapy in pre- versus postmenopausal patients with steroid hormone receptor-positive breast cancer: results from a large population-based cohort of a cancer registry.
E C Inwald, M Koller, +7 authors, O Ortmann.
J Cancer Res Clin Oncol, 2015 Aug 09; 141(12). PMID: 26253629    Free PMC article.
Progress in adjuvant chemotherapy for breast cancer: an overview.
Jesus Anampa, Della Makower, Joseph A Sparano.
BMC Med, 2015 Aug 19; 13. PMID: 26278220    Free PMC article.
Highly Cited. Review.
Impact of Fertility Concerns on Tamoxifen Initiation and Persistence.
Natalia C Llarena, Samantha L Estevez, Susan L Tucker, Jacqueline S Jeruss.
J Natl Cancer Inst, 2015 Aug 27; 107(10). PMID: 26307641    Free PMC article.
Current medical treatment of estrogen receptor-positive breast cancer.
Franco Lumachi, Davide A Santeufemia, Stefano Mm Basso.
World J Biol Chem, 2015 Sep 01; 6(3). PMID: 26322178    Free PMC article.
Review.
Boronic prodrug of 4-hydroxytamoxifen is more efficacious than tamoxifen with enhanced bioavailability independent of CYP2D6 status.
Qiu Zhong, Changde Zhang, +3 authors, Guangdi Wang.
BMC Cancer, 2015 Sep 12; 15. PMID: 26354796    Free PMC article.
High PD-L1 expression was associated with poor prognosis in 870 Chinese patients with breast cancer.
Tao Qin, Yin-duo Zeng, +11 authors, Shu-sen Wang.
Oncotarget, 2015 Sep 18; 6(32). PMID: 26378017    Free PMC article.
Highly Cited.
Targeting Breast Cancer Metastasis.
Xin Jin, Ping Mu.
Breast Cancer (Auckl), 2015 Sep 19; 9(Suppl 1). PMID: 26380552    Free PMC article.
Review.
Tamoxifen retinopathy: a case report.
Lingling Wang, Heng Miao, Xiaoxin Li.
Springerplus, 2015 Sep 26; 4. PMID: 26405621    Free PMC article.
Prospective Validation of a 21-Gene Expression Assay in Breast Cancer.
Joseph A Sparano, Robert J Gray, +28 authors, George W Sledge.
N Engl J Med, 2015 Sep 29; 373(21). PMID: 26412349    Free PMC article.
Highly Cited.
Statistical controversies in clinical research: long-term follow-up of clinical trials in cancer.
J Cuzick.
Ann Oncol, 2015 Oct 05; 26(12). PMID: 26433395    Free PMC article.
Review.
Breast Cancer: Conventional Diagnosis and Treatment Modalities and Recent Patents and Technologies.
Mohamed I Nounou, Fatema ElAmrawy, +3 authors, Hussaini Syed-Sha-Qhattal.
Breast Cancer (Auckl), 2015 Oct 16; 9(Suppl 2). PMID: 26462242    Free PMC article.
Review.
The Role of MicroRNAs as Predictors of Response to Tamoxifen Treatment in Breast Cancer Patients.
Nina G Egeland, Siri Lunde, +5 authors, Håvard Søiland.
Int J Mol Sci, 2015 Oct 17; 16(10). PMID: 26473850    Free PMC article.
Review.
Prognostic impact of a single-nucleotide polymorphism near the CTSO gene in hormone receptor-positive breast cancer patients.
Yukari Hato, Naoto Kondo, +8 authors, Tatsuya Toyama.
Int J Clin Oncol, 2015 Oct 21; 21(3). PMID: 26482374
SEOM clinical guidelines in early-stage breast cancer 2015.
J A Garcia-Saenz, B Bermejo, +7 authors, E Ciruelos.
Clin Transl Oncol, 2015 Oct 27; 17(12). PMID: 26497356    Free PMC article.
Targeting glycolysis by 3-bromopyruvate improves tamoxifen cytotoxicity of breast cancer cell lines.
Yasmin M Attia, Hanan S El-Abhar, Mahmoud M Al Marzabani, Samia A Shouman.
BMC Cancer, 2015 Nov 04; 15. PMID: 26526196    Free PMC article.
Tamoxifen therapy benefit predictive signature coupled with prognostic signature of post-operative recurrent risk for early stage ER+ breast cancer.
Hao Cai, Xiangyu Li, +6 authors, Zheng Guo.
Oncotarget, 2015 Nov 04; 6(42). PMID: 26527319    Free PMC article.
Prospective assessment of the decision-making impact of the Breast Cancer Index in recommending extended adjuvant endocrine therapy for patients with early-stage ER-positive breast cancer.
Tara Sanft, Bilge Aktas, +11 authors, Lajos Pusztai.
Breast Cancer Res Treat, 2015 Nov 19; 154(3). PMID: 26578401    Free PMC article.
The Impact of Endocrine Therapy on Cognitive Functions of Breast Cancer Patients: A Systematic Review.
Ioannis Bakoyiannis, Eleousa-Alexandra Tsigka, Despina Perrea, Vasilios Pergialiotis.
Clin Drug Investig, 2015 Dec 02; 36(2). PMID: 26619839
Systematic Review.
Levonorgestrel intrauterine system for endometrial protection in women with breast cancer on adjuvant tamoxifen.
Sally Dominick, Martha Hickey, Jason Chin, H Irene Su.
Cochrane Database Syst Rev, 2015 Dec 10; (12). PMID: 26649916    Free PMC article.
Systematic Review.
Time to Surgery and Breast Cancer Survival in the United States.
Richard J Bleicher, Karen Ruth, +8 authors, Brian L Egleston.
JAMA Oncol, 2015 Dec 15; 2(3). PMID: 26659430    Free PMC article.
Highly Cited.
Recommendations from the EGAPP Working Group: does the use of Oncotype DX tumor gene expression profiling to guide treatment decisions improve outcomes in patients with breast cancer?
Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group*.
Genet Med, 2015 Dec 19; 18(8). PMID: 26681310
The Modern Landscape of Endocrine Therapy for Premenopausal Women with Breast Cancer.
Lorenzo Rossi, Olivia Pagani.
Breast Care (Basel), 2015 Dec 22; 10(5). PMID: 26688677    Free PMC article.
Review.
Managing breast cancer in younger women: challenges and solutions.
Foluso O Ademuyiwa, Amy Cyr, Jennifer Ivanovich, Maria A Thomas.
Breast Cancer (Dove Med Press), 2016 Jan 06; 8. PMID: 26730210    Free PMC article.
Review.
Adjuvant treatment for older women with invasive breast cancer.
Trevor A Jolly, Grant R Williams, +4 authors, Hyman B Muss.
Womens Health (Lond), 2016 Jan 16; 12(1). PMID: 26767315    Free PMC article.
Review.
Characterizing and quantifying the effects of breast cancer therapy using mathematical modeling.
Walter M Gregory, Christopher J Twelves, +4 authors, David A Cameron.
Breast Cancer Res Treat, 2016 Jan 20; 155(2). PMID: 26783036    Free PMC article.
Extracellular vesicles in breast cancer drug resistance and their clinical application.
Shentong Yu, Yifang Wei, +3 authors, Jian Zhang.
Tumour Biol, 2016 Jan 23; 37(3). PMID: 26797784
Review.
Adjuvant hormonal therapy in premenopausal women with breast cancer.
Lillian Smyth, Clifford Hudis.
Indian J Med Paediatr Oncol, 2016 Jan 27; 36(4). PMID: 26811586    Free PMC article.
Perceptions, Attributions, and Emotions Toward Endocrine Therapy in Young Women with Breast Cancer.
Hayley E Walker, Shoshana M Rosenberg, +2 authors, Ann H Partridge.
J Adolesc Young Adult Oncol, 2016 Jan 27; 5(1). PMID: 26812461    Free PMC article.
Effect of young age, positive margins, and triple negative status on disease recurrence after breast conserving therapy.
Panuwat Lertsithichai, Bundit Sakulchairungreung, +5 authors, Youwanush Kongdan.
Gland Surg, 2016 Feb 09; 5(1). PMID: 26855904    Free PMC article.
Targeted therapies with companion diagnostics in the management of breast cancer: current perspectives.
Meagan B Myers.
Pharmgenomics Pers Med, 2016 Feb 10; 9. PMID: 26858530    Free PMC article.
Review.
Analysis of factors affecting endocrine therapy resistance in breast cancer.
Min Zhang, Hui Chen, Jun Gu.
Oncol Lett, 2016 Feb 13; 11(1). PMID: 26870221    Free PMC article.
Patterns in target-directed breast cancer research.
Sofia Torres, Christine Simmons, +3 authors, Maureen Trudeau.
Springerplus, 2016 Feb 16; 5. PMID: 26877907    Free PMC article.
Heterogeneity of leukemia-initiating capacity of chronic myelogenous leukemia stem cells.
Bin Zhang, Ling Li, +4 authors, Ravi Bhatia.
J Clin Invest, 2016 Feb 16; 126(3). PMID: 26878174    Free PMC article.
Inhibition of breast cancer with transdermal tamoxifen-encapsulated lipoplex.
Yu-Ling Lin, Chia-Hung Chen, +8 authors, Kuang-Wen Liao.
J Nanobiotechnology, 2016 Feb 20; 14. PMID: 26892504    Free PMC article.
Targeting dormant micrometastases: rationale, evidence to date and clinical implications.
Robert E Hurst, Anja Bastian, Lora Bailey-Downs, Michael A Ihnat.
Ther Adv Med Oncol, 2016 Mar 02; 8(2). PMID: 26929788    Free PMC article.
Review.
Understanding the molecular mechanisms of cancer prevention by dietary phytochemicals: From experimental models to clinical trials.
Girish B Maru, Rasika R Hudlikar, +2 authors, Manoj B Mahimkar.
World J Biol Chem, 2016 Mar 17; 7(1). PMID: 26981198    Free PMC article.
Review.
Emerging therapeutic targets in metastatic progression: A focus on breast cancer.
Zhuo Li, Yibin Kang.
Pharmacol Ther, 2016 Mar 24; 161. PMID: 27000769    Free PMC article.
Review.
Mammographic Density as a Biosensor of Tamoxifen Effectiveness in Adjuvant Endocrine Treatment of Breast Cancer: Opportunities and Implications.
Maeve Mullooly, Ruth M Pfeiffer, +10 authors, Gretchen L Gierach.
J Clin Oncol, 2016 Mar 30; 34(18). PMID: 27022110    Free PMC article.
The association between the duration of fluoropyrimidine-based adjuvant chemotherapy and survival in stage II or III gastric cancer.
Seong-Geun Kim, Sun-Hwi Hwang.
World J Surg Oncol, 2016 Apr 04; 14. PMID: 27039375    Free PMC article.
Adjuvant endocrine therapy in premenopausal women with breast cancer.
Kunal C Kadakia, N Lynn Henry.
Clin Adv Hematol Oncol, 2016 Apr 09; 13(10). PMID: 27058571    Free PMC article.
Vaginal Health During Breast Cancer Treatment.
Sandy J Falk, Sharon Bober.
Curr Oncol Rep, 2016 Apr 15; 18(5). PMID: 27074843
Review.
Psychosocial factors related to non-persistence with adjuvant endocrine therapy among women with breast cancer: the Breast Cancer Quality of Care Study (BQUAL).
Dawn L Hershman, Lawrence H Kushi, +10 authors, Alfred I Neugut.
Breast Cancer Res Treat, 2016 Apr 18; 157(1). PMID: 27086286    Free PMC article.
Behavioral Interventions to Enhance Adherence to Hormone Therapy in Breast Cancer Survivors: A Systematic Literature Review.
Alejandra Hurtado-de-Mendoza, Mark L Cabling, +2 authors, Vanessa B Sheppard.
Clin Breast Cancer, 2016 May 03; 16(4). PMID: 27133733    Free PMC article.
Systematic Review.
Lower Breast Cancer Mortality in Patients Aged 70+ Achievable.
J Matthias Wenderlein.
Dtsch Arztebl Int, 2016 May 10; 113(16). PMID: 27159144    Free PMC article.
Prognostic Impact of the Combination of Recurrence Score and Quantitative Estrogen Receptor Expression (ESR1) on Predicting Late Distant Recurrence Risk in Estrogen Receptor-Positive Breast Cancer After 5 Years of Tamoxifen: Results From NRG Oncology/National Surgical Adjuvant Breast and Bowel Project B-28 and B-14.
Norman Wolmark, Eleftherios P Mamounas, +6 authors, Soonmyung Paik.
J Clin Oncol, 2016 May 25; 34(20). PMID: 27217450    Free PMC article.
Treatment Adherence and Its Impact on Disease-Free Survival in the Breast International Group 1-98 Trial of Tamoxifen and Letrozole, Alone and in Sequence.
Jacquie H Chirgwin, Anita Giobbie-Hurder, +12 authors, Beat Thürlimann.
J Clin Oncol, 2016 May 25; 34(21). PMID: 27217455    Free PMC article.
Highly Cited.
Tamoxifen Dose Escalation in Patients With Diminished CYP2D6 Activity Normalizes Endoxifen Concentrations Without Increasing Toxicity.
Daniel L Hertz, Allison Deal, +19 authors, William J Irvin.
Oncologist, 2016 May 27; 21(7). PMID: 27226358    Free PMC article.
Significance of Ovarian Function Suppression in Endocrine Therapy for Breast Cancer in Pre-Menopausal Women.
A Scharl, A Salterberg.
Geburtshilfe Frauenheilkd, 2016 May 31; 76(5). PMID: 27239060    Free PMC article.
Review.
Extending Aromatase-Inhibitor Adjuvant Therapy to 10 Years.
Paul E Goss, James N Ingle, +17 authors, Wendy R Parulekar.
N Engl J Med, 2016 Jun 07; 375(3). PMID: 27264120    Free PMC article.
Highly Cited.
A Raloxifene Withdrawal Response: Translational Research, Definitions, and Clinical Applications.
V Craig Jordan.
Integr Cancer Ther, 2016 Jun 09; 15(3). PMID: 27271771    Free PMC article.
Targeting BET bromodomain proteins in solid tumors.
Vaibhav Sahai, Amanda J Redig, +2 authors, Hidayatullah G Munshi.
Oncotarget, 2016 Jun 11; 7(33). PMID: 27283767    Free PMC article.
Review.
Breast Cancer-Specific Mortality Pattern and Its Changing Feature According to Estrogen Receptor Status in Two Time Periods.
Junjie Li, Yirong Liu, Yizhou Jiang, Zhimin Shao.
PLoS One, 2016 Jun 15; 11(6). PMID: 27299729    Free PMC article.
Metformin and cancer: Quo vadis et cui bono?
Javier A Menendez, Begoña Martin-Castillo, Jorge Joven.
Oncotarget, 2016 Jul 01; 7(34). PMID: 27356748    Free PMC article.
[Clinical and epidemiological cancer registration in Germany].
D Hölzel, G Schubert-Fritschle, +2 authors, J Engel.
Pathologe, 2016 Jul 08; 37(4). PMID: 27384334
Review.
Factors associated with late recurrence after completion of 5-year adjuvant tamoxifen in estrogen receptor positive breast cancer.
Eun-Shin Lee, Wonshik Han, +9 authors, Eun Sook Lee.
BMC Cancer, 2016 Jul 09; 16. PMID: 27388210    Free PMC article.
Prediction of ovarian function in premenopausal breast cancer patients with amenorrhoea after chemotherapy: a simple clinical score.
Xiao Shi Li, Qing Lv, Zheng Gui Du, Jie Chen.
Springerplus, 2016 Jul 28; 5(1). PMID: 27462500    Free PMC article.
MiR-4653-3p and its target gene FRS2 are prognostic biomarkers for hormone receptor positive breast cancer patients receiving tamoxifen as adjuvant endocrine therapy.
XiaoRong Zhong, GuiQin Xie, +8 authors, Hong Zheng.
Oncotarget, 2016 Aug 18; 7(38). PMID: 27533459    Free PMC article.
Young Age Is Associated with Increased Locoregional Recurrence in Node-Positive Breast Cancer with Luminal Subtypes.
Sang-Won Kim, Mison Chun, +5 authors, Seung Hee Kang.
Cancer Res Treat, 2016 Aug 25; 49(2). PMID: 27554479    Free PMC article.
Factors that predict recurrence later than 5 years after initial treatment in operable breast cancer.
Pattaraporn Wangchinda, Suthinee Ithimakin.
World J Surg Oncol, 2016 Aug 26; 14(1). PMID: 27557635    Free PMC article.
Factors related to the experience of menopausal symptoms in women prescribed tamoxifen.
Zoe Moon, Myra S Hunter, Rona Moss-Morris, Lyndsay Dawn Hughes.
J Psychosom Obstet Gynaecol, 2016 Sep 02; 38(3). PMID: 27583832    Free PMC article.
Tamoxifen and amphetamine abuse: Are there therapeutic possibilities?
Sarah Mikelman, Natalie Mardirossian, Margaret E Gnegy.
J Chem Neuroanat, 2016 Sep 03; 83-84. PMID: 27585851    Free PMC article.
Review.
Persistence to 5-year hormonal breast cancer therapy: a French national population-based study.
Pauline Bosco-Lévy, Jeremy Jové, +3 authors, Julien Bezin.
Br J Cancer, 2016 Sep 07; 115(8). PMID: 27599040    Free PMC article.
National Prociency Testing Result of CYP2D6*10 Genotyping for Adjuvant Tamoxifen Therapy in China.
Guigao Lin, Kuo Zhang, +3 authors, Jinming Li.
PLoS One, 2016 Sep 08; 11(9). PMID: 27603206    Free PMC article.
From High-Throughput Microarray-Based Screening to Clinical Application: The Development of a Second Generation Multigene Test for Breast Cancer Prognosis.
Jan C Brase, Ralf Kronenwett, +2 authors, Marcus Schmidt.
Microarrays (Basel), 2013 Jan 01; 2(3). PMID: 27605191    Free PMC article.
Review.
Postoperative hormonal therapy prevents recovery of neurological damage after surgery in patients with breast cancer.
Atsushi Sekiguchi, Chiho Sato, +9 authors, Ryuta Kawashima.
Sci Rep, 2016 Oct 07; 6. PMID: 27708377    Free PMC article.
The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer.
Emily K Law, Anieta M Sieuwerts, +12 authors, Reuben S Harris.
Sci Adv, 2016 Oct 13; 2(10). PMID: 27730215    Free PMC article.
Highly Cited.
Oncology providers' perspectives on endocrine therapy prescribing and management.
Stephanie B Wheeler, Megan C Roberts, +5 authors, Jo Anne Earp.
Patient Prefer Adherence, 2016 Oct 21; 10. PMID: 27757021    Free PMC article.
Exosomes-mediate microRNAs transfer in breast cancer chemoresistance regulation.
Juliana Carvalho Santos, Marcelo Lima Ribeiro, +2 authors, Sophie Françoise Derchain.
Am J Cancer Res, 2016 Nov 09; 6(10). PMID: 27822407    Free PMC article.
Review.
Impact of tamoxifen therapy on fertility in breast cancer survivors.
Lisa M Shandley, Jessica B Spencer, +4 authors, Penelope P Howards.
Fertil Steril, 2016 Nov 27; 107(1). PMID: 27887709    Free PMC article.
The Association Between Out-of-Pocket Costs and Adherence to Adjuvant Endocrine Therapy Among Newly Diagnosed Breast Cancer Patients.
Albert J Farias, Ryan N Hansen, +3 authors, Beti Thompson.
Am J Clin Oncol, 2016 Nov 29; 41(7). PMID: 27893470    Free PMC article.
Cytochrome P-450 2D6 (CYP2D6) Genotype and Breast Cancer Recurrence in Tamoxifen-Treated Patients: Evaluating the Importance of Loss of Heterozygosity.
Thomas P Ahern, Daniel L Hertz, +7 authors, Deirdre P Cronin-Fenton.
Am J Epidemiol, 2016 Dec 19; 185(2). PMID: 27988492    Free PMC article.
Review.
Recent advances in the medical treatment of breast cancer.
Daniel A Vorobiof.
F1000Res, 2016 Dec 19; 5. PMID: 27990275    Free PMC article.
Review.
Cardiotoxicity of aromatase inhibitors and tamoxifen in postmenopausal women with breast cancer: a systematic review and meta-analysis of randomized controlled trials.
F Khosrow-Khavar, K B Filion, +4 authors, L Azoulay.
Ann Oncol, 2016 Dec 22; 28(3). PMID: 27998966    Free PMC article.
Systematic Review.
An Antiestrogenic Activity Score for tamoxifen and its metabolites is associated with breast cancer outcome.
A H M de Vries Schultink, X Alexi, +10 authors, J H Beijnen.
Breast Cancer Res Treat, 2016 Dec 23; 161(3). PMID: 28005246    Free PMC article.
The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE".
Peter Savas, Zhi Ling Teo, +17 authors, Sherene Loi.
PLoS Med, 2016 Dec 28; 13(12). PMID: 28027312    Free PMC article.
Highly Cited.
Second Opinions From Medical Oncologists for Early-Stage Breast Cancer: Prevalence, Correlates, and Consequences.
Allison W Kurian, Christopher R Friese, +5 authors, Steven J Katz.
JAMA Oncol, 2016 Dec 30; 3(3). PMID: 28033448    Free PMC article.
Association Between Out-Of-Pocket Costs, Race/Ethnicity, and Adjuvant Endocrine Therapy Adherence Among Medicare Patients With Breast Cancer.
Albert J Farias, Xianglin L Du.
J Clin Oncol, 2016 Dec 31; 35(1). PMID: 28034069    Free PMC article.
First report on molecular breast cancer subtypes and their clinico-pathological characteristics in Eastern Morocco: series of 2260 cases.
Manal Elidrissi Errahhali, Mounia Elidrissi Errahhali, +3 authors, Mohammed Bellaoui.
BMC Womens Health, 2017 Jan 11; 17(1). PMID: 28068979    Free PMC article.
Breast Cancer Profile among Patients with a History of Chemoprevention.
Freya R Schnabel, Sarah Pivo, +4 authors, Amber Guth.
Int J Breast Cancer, 2017 Jan 13; 2016. PMID: 28078143    Free PMC article.
Novel Selective Estrogen Receptor Downregulators (SERDs) Developed against Treatment-Resistant Breast Cancer.
Rui Xiong, Jiong Zhao, +7 authors, Gregory R J Thatcher.
J Med Chem, 2017 Jan 25; 60(4). PMID: 28117994    Free PMC article.
Prevalence of preterm, low birthweight, and small for gestational age delivery after breast cancer diagnosis: a population-based study.
Kristin Zeneé Black, Hazel B Nichols, Eugenia Eng, Diane Louise Rowley.
Breast Cancer Res, 2017 Feb 02; 19(1). PMID: 28143580    Free PMC article.
Polymorphisms of ESR1, UGT1A1, HCN1, MAP3K1 and CYP2B6 are associated with the prognosis of hormone receptor-positive early breast cancer.
Sung-Hsin Kuo, Shi-Yi Yang, +4 authors, Chiun-Sheng Huang.
Oncotarget, 2017 Feb 09; 8(13). PMID: 28178648    Free PMC article.
Ovarian Function Suppression in Premenopausal Women with Early-Stage Breast Cancer.
Matteo Lambertini, Lucia Del Mastro, +3 authors, Evandro de Azambuja.
Curr Treat Options Oncol, 2017 Feb 12; 18(1). PMID: 28185173
Review.
Breast Cancer Outcomes After Diagnosis of Hormone-positive Breast Cancer and Subsequent Pregnancy in the Tamoxifen Era.
Lauren Nye, Alfred Rademaker, William J Gradishar.
Clin Breast Cancer, 2017 Feb 12; 17(4). PMID: 28185739    Free PMC article.
Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles.
Pasquale Sansone, Marjan Berishaj, +18 authors, Jacqueline Bromberg.
Cancer Res, 2017 Feb 17; 77(8). PMID: 28202520    Free PMC article.
Understanding Breast Cancer Survivors' Beliefs and Concerns About Adjuvant Hormonal Therapy: Promoting Adherence.
Alejandra Hurtado-de-Mendoza, Roxanne E Jensen, Yvonne Jennings, Vanessa B Sheppard.
J Cancer Educ, 2017 Feb 17; 33(2). PMID: 28205022    Free PMC article.
Endometrial polyp surveillance in premenopausal breast cancer patients using tamoxifen.
Se Jeong Jeon, Jae Il Lee, +4 authors, Yong Sang Song.
Obstet Gynecol Sci, 2017 Feb 22; 60(1). PMID: 28217668    Free PMC article.
Extended Endocrine Therapy: Is 5 Years Enough?
Manali A Bhave, N Lynn Henry.
Curr Oncol Rep, 2017 Mar 03; 19(3). PMID: 28251491
Review.
Anordrin Eliminates Tamoxifen Side Effects without Changing Its Antitumor Activity.
Wenwen Gu, Wenping Xu, +11 authors, Jun Yang.
Sci Rep, 2017 Mar 08; 7. PMID: 28266626    Free PMC article.
Utilization of gynecologic services in women with breast cancer receiving hormonal therapy.
Jason D Wright, Vrunda B Desai, +7 authors, Dawn L Hershman.
Am J Obstet Gynecol, 2017 Mar 28; 217(1). PMID: 28341383    Free PMC article.
Adjuvant Endocrine Therapy in Breast Cancer: Evolving Paradigms in Premenopausal Women.
Lorenzo Rossi, Olivia Pagani.
Curr Treat Options Oncol, 2017 Apr 26; 18(5). PMID: 28439796
Review.
Long-Term Follow-Up of the Intergroup Exemestane Study.
James P Morden, Isabel Alvarez, +18 authors, R Charles Coombes.
J Clin Oncol, 2017 May 04; 35(22). PMID: 28467729    Free PMC article.
Prognostic and predictive value of low estrogen receptor expression in breast cancer.
A Bouchard-Fortier, L Provencher, C Blanchette, C Diorio.
Curr Oncol, 2017 May 12; 24(2). PMID: 28490933    Free PMC article.
Embryonic transcription factor SOX9 drives breast cancer endocrine resistance.
Rinath Jeselsohn, MacIntosh Cornwell, +20 authors, Myles Brown.
Proc Natl Acad Sci U S A, 2017 May 17; 114(22). PMID: 28507152    Free PMC article.
Acquired Tamoxifen Resistance in MCF-7 Breast Cancer Cells Requires Hyperactivation of eIF4F-Mediated Translation.
Dedra H Fagan, Lynsey M Fettig, +6 authors, Douglas Yee.
Horm Cancer, 2017 Jun 04; 8(4). PMID: 28577281    Free PMC article.
Extended adjuvant endocrine therapy in early breast cancer: a meta-analysis of published randomized trials.
Ezzeldin M Ibrahim, Marwan R Al-Hajeili, +2 authors, Ahmed A Refae.
Med Oncol, 2017 Jun 18; 34(7). PMID: 28620883
Deconstructing Decisions to Initiate, Maintain, or Discontinue Adjuvant Endocrine Therapy in Breast Cancer Survivors: A Mixed-Methods Study.
Shirley M Bluethmann, Caitlin C Murphy, +3 authors, Leona Kay Bartholomew.
Oncol Nurs Forum, 2017 Jun 22; 44(3). PMID: 28635973    Free PMC article.
Nomegestrol Acetate Suppresses Human Endometrial Cancer RL95-2 Cells Proliferation In Vitro and In Vivo Possibly Related to Upregulating Expression of SUFU and Wnt7a.
A-Ying Ma, Shu-Wu Xie, Jie-Yun Zhou, Yan Zhu.
Int J Mol Sci, 2017 Jun 24; 18(7). PMID: 28640224    Free PMC article.
Current advances in endocrine therapy options for premenopausal women with hormone receptor positive breast cancer.
Mary L Gemignani, David J Hetzel.
Gynecol Oncol, 2017 Jul 01; 147(1). PMID: 28662774    Free PMC article.
Review.
Breast cancer subtype and stage are prognostic of time from breast cancer diagnosis to brain metastasis development.
Anurag Saraf, Christopher S Grubb, +15 authors, Tony J C Wang.
J Neurooncol, 2017 Jul 05; 134(2). PMID: 28674973
Provider perspectives on barriers and facilitators to adjuvant endocrine therapy-related symptom management.
Cleo A Samuel, Kea Turner, +4 authors, G J van Londen.
Support Care Cancer, 2017 Jul 07; 25(12). PMID: 28681126    Free PMC article.
Self-Assembling RADA16-I Peptide Hydrogel Scaffold Loaded with Tamoxifen for Breast Reconstruction.
Huimin Wu, Ting Zhou, +2 authors, Feng Xu.
Biomed Res Int, 2017 Jul 12; 2017. PMID: 28691024    Free PMC article.
Flexible small molecular anti-estrogens with N,N-dialkylated-2,5-diethoxy-4-morpholinoaniline scaffold targets multiple estrogen receptor conformations.
Bethany K Asare, Emmanuel Yawson, Rajendram V Rajnarayanan.
Cell Cycle, 2017 Jul 21; 16(15). PMID: 28723234    Free PMC article.
Physical Activity and Survival in Women With Advanced Breast Cancer.
Oxana Palesh, Charles Kamen, +4 authors, Cheryl Koopman.
Cancer Nurs, 2017 Jul 21; 41(4). PMID: 28727578    Free PMC article.
Adjuvant endocrine monotherapy for postmenopausal early breast cancer patients with hormone-receptor positive: a systemic review and network meta-analysis.
Zhu Yu, Xiaojing Guo, +5 authors, Haitian Zhang.
Breast Cancer, 2017 Jul 30; 25(1). PMID: 28755088    Free PMC article.
Review.
Extended Adjuvant Endocrine Therapy in Hormone Receptor-Positive Early Breast Cancer.
Dara B Bracken-Clarke, Mairi W Lucas, Michaela J Higgins.
Breast Care (Basel), 2017 Aug 09; 12(3). PMID: 28785180    Free PMC article.
Review.
Identifying Biomarkers to Select Patients with Early Breast Cancer Suitable for Extended Adjuvant Endocrine Therapy.
Ivana Sestak.
Breast Care (Basel), 2017 Aug 09; 12(3). PMID: 28785181    Free PMC article.
Review.
Temporal influence of endocrine therapy with tamoxifen and chemotherapy on nutritional risk and obesity in breast cancer patients.
Mariana Tavares Miranda Lima, Kamila Pires de Carvalho, +4 authors, Yara Cristina de Paiva Maia.
BMC Cancer, 2017 Aug 31; 17(1). PMID: 28851304    Free PMC article.
Tamoxifen Pharmacovigilance: Implications for Safe Use in the Future.
Demetra Antimisiaris, Ki-Hwan Gabriel Bae, Laura Morton, Zahara Gully.
Consult Pharm, 2017 Sep 01; 32(9). PMID: 28855012    Free PMC article.
Increased risk of SSEs in bone-only metastatic breast cancer patients treated with zoledronic acid.
Masashi Yanae, Shinichiro Fujimoto, +11 authors, Shozo Nishida.
J Bone Oncol, 2017 Sep 09; 8. PMID: 28884071    Free PMC article.
Nationwide Case-Control Study Examining the Association between Tamoxifen Use and Alzheimer's Disease in Aged Women with Breast Cancer in Taiwan.
Kuan-Fu Liao, Cheng-Li Lin, Shih-Wei Lai.
Front Pharmacol, 2017 Sep 21; 8. PMID: 28928665    Free PMC article.
Tamoxifen usage correlates with increased risk of Parkinson's disease in older women with breast cancer: a case-control study in Taiwan.
Hsien-Feng Lin, Kuan-Fu Liao, +2 authors, Shih-Wei Lai.
Eur J Clin Pharmacol, 2017 Oct 03; 74(1). PMID: 28967041
Alternative Splicing in Breast Cancer and the Potential Development of Therapeutic Tools.
Nancy Martínez-Montiel, Maricruz Anaya-Ruiz, Martín Pérez-Santos, Rebeca D Martínez-Contreras.
Genes (Basel), 2017 Oct 06; 8(10). PMID: 28981467    Free PMC article.
Review.
Differential presentation and survival of de novo and recurrent metastatic breast cancer over time: 1990-2010.
Judith A Malmgren, Musa Mayer, Mary K Atwood, Henry G Kaplan.
Breast Cancer Res Treat, 2017 Oct 19; 167(2). PMID: 29039120    Free PMC article.
ER-positive breast cancer patients with more than three positive nodes or grade 3 tumors are at high risk of late recurrence after 5-year adjuvant endocrine therapy.
Fangbin Song, Jianbing Zhang, +6 authors, Junming Xu.
Onco Targets Ther, 2017 Oct 19; 10. PMID: 29042797    Free PMC article.
Use of 21-gene recurrence score assay to individualize adjuvant chemotherapy recommendations in ER+/HER2- node positive breast cancer-A National Cancer Database study.
Prema P Peethambaram, Tanya L Hoskin, +3 authors, Judy C Boughey.
NPJ Breast Cancer, 2017 Oct 27; 3. PMID: 29067357    Free PMC article.
Hypomethylation associated enhanced transcription of trefoil factor-3 mediates tamoxifen-stimulated oncogenicity of ER+ endometrial carcinoma cells.
Vijay Pandey, Min Zhang, +10 authors, Peter E Lobie.
Oncotarget, 2017 Nov 05; 8(44). PMID: 29100386    Free PMC article.
20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years.
Hongchao Pan, Richard Gray, +9 authors, EBCTCG.
N Engl J Med, 2017 Nov 09; 377(19). PMID: 29117498    Free PMC article.
Highly Cited.
First Prospective Multicenter Italian Study on the Impact of the 21-Gene Recurrence Score in Adjuvant Clinical Decisions for Patients with ER Positive/HER2 Negative Breast Cancer.
Maria Vittoria Dieci, Valentina Guarneri, +15 authors, PierFranco Conte.
Oncologist, 2017 Nov 15; 23(3). PMID: 29133514    Free PMC article.
Prognostic value of PAM50 and risk of recurrence score in patients with early-stage breast cancer with long-term follow-up.
Hege O Ohnstad, Elin Borgen, +11 authors, Bjørn Naume.
Breast Cancer Res, 2017 Nov 16; 19(1). PMID: 29137653    Free PMC article.
A unifying biology of sex steroid-induced apoptosis in prostate and breast cancers.
Philipp Y Maximov, Balkees Abderrahman, +3 authors, V Craig Jordan.
Endocr Relat Cancer, 2017 Nov 23; 25(2). PMID: 29162647    Free PMC article.
Review.
Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients.
Thomas Helland, Nina Henne, +12 authors, Håvard Søiland.
Breast Cancer Res, 2017 Dec 01; 19(1). PMID: 29183390    Free PMC article.
Coactivation of Estrogen Receptor and IKKβ Induces a Dormant Metastatic Phenotype in ER-Positive Breast Cancer.
Lamiaa El-Shennawy, Oleksii Dubrovskyi, +5 authors, Jonna Frasor.
Cancer Res, 2017 Dec 13; 78(4). PMID: 29229606    Free PMC article.
Endocrine Therapy for Early Breast Cancer: Updated Review.
Alexander Tremont, Jonathan Lu, John T Cole.
Ochsner J, 2017 Dec 13; 17(4). PMID: 29230126    Free PMC article.
Review.
Pharmacogenomics Guided-Personalization of Warfarin and Tamoxifen.
Theodore J Wigle, Laura E Jansen, Wendy A Teft, Richard B Kim.
J Pers Med, 2017 Dec 14; 7(4). PMID: 29236081    Free PMC article.
Review.
Variations in plasma concentrations of tamoxifen metabolites and the effects of genetic polymorphisms on tamoxifen metabolism in Korean patients with breast cancer.
Hye In Woo, Se Kyung Lee, +6 authors, Soo-Youn Lee.
Oncotarget, 2017 Dec 17; 8(59). PMID: 29245979    Free PMC article.
Impact of persistence on survival of patients with breast cancer treated with endocrine therapy in Northeast China: a prospective study.
Peng Xing, Huiting Dong, +7 authors, Jiguang Li.
Oncotarget, 2017 Dec 20; 8(60). PMID: 29254265    Free PMC article.
Aromatase inhibitors and the risk of colorectal cancer in postmenopausal women with breast cancer.
F Khosrow-Khavar, H Yin, +2 authors, L Azoulay.
Ann Oncol, 2018 Jan 03; 29(3). PMID: 29293897    Free PMC article.
Facilitating adherence to endocrine therapy in breast cancer: stability and predictive power of treatment expectations in a 2-year prospective study.
Yiqi Pan, Sarah R Heisig, +4 authors, Yvonne Nestoriuc.
Breast Cancer Res Treat, 2018 Jan 14; 168(3). PMID: 29330625    Free PMC article.
Optimal duration of adjuvant endocrine therapy: how to apply the newest data.
Kerstin Wimmer, Stephanie Strobl, +5 authors, Michael Gnant.
Ther Adv Med Oncol, 2018 Jan 19; 9(11). PMID: 29344105    Free PMC article.
Review.
Luminal-like HER2-negative stage IA breast cancer: a multicenter retrospective study on long-term outcome with propensity score analysis.
Carmine De Angelis, Massimo Di Maio, +12 authors, Grazia Arpino.
Oncotarget, 2018 Jan 20; 8(68). PMID: 29348868    Free PMC article.
Psychometric properties of the Beliefs about Medicine Questionnaire-adjuvant endocrine therapy (BMQ-AET) for women taking AETs following early-stage breast cancer.
Jo Brett, Nick J Hulbert-Williams, +8 authors, Eila Watson.
Health Psychol Open, 2018 Jan 31; 4(2). PMID: 29379627    Free PMC article.
Interventions to improve endocrine therapy adherence in breast cancer survivors: what is the evidence?
Ekim Ekinci, Salima Nathoo, +5 authors, Meghana V Trivedi.
J Cancer Surviv, 2018 Feb 06; 12(3). PMID: 29396760
Review.
Extended Adjuvant Aromatase Inhibitor Therapy in Post-Menopausal Women.
Stephen M Schleicher, Maura N Dickler.
Curr Breast Cancer Rep, 2018 Feb 06; 9(4). PMID: 29399271    Free PMC article.
Physical and Emotional Experiences of Chemotherapy: a Qualitative Study among Women with Breast Cancer in Southern Thailand
Dusanee Suwankhong, Pranee Liamputtong.
Asian Pac J Cancer Prev, 2018 Feb 27; 19(2). PMID: 29480995    Free PMC article.
Adjuvant endocrine therapy after breast cancer: a qualitative study of factors associated with adherence.
Jo Brett, Mary Boulton, +7 authors, Eila K Watson.
Patient Prefer Adherence, 2018 Mar 03; 12. PMID: 29497284    Free PMC article.
The tipping point: Tamoxifen toxicity, central serous chorioretinopathy, and the role of estrogen and its receptors.
Nicole Koulisis, Stavros N Moysidis, +2 authors, Amir H Kashani.
Am J Ophthalmol Case Rep, 2016 May 18; 3. PMID: 29503899    Free PMC article.
Understanding Biomarkers in Early-Stage Invasive Breast Cancer: Tools From the ASCO Clinical Guideline.
Kelley D Mayden.
J Adv Pract Oncol, 2016 Sep 01; 7(6). PMID: 29588871    Free PMC article.
Review.
Mammographic density changes following discontinuation of tamoxifen in premenopausal women with oestrogen receptor-positive breast cancer.
Won Hwa Kim, Nariya Cho, Young-Seon Kim, Ann Yi.
Eur Radiol, 2018 Apr 08; 28(8). PMID: 29626240
Obesity and outcome of post-menopausal women receiving adjuvant letrozole for breast cancer.
Jamal Zekri, Kamel Farag, Ahmed Allithy.
Ecancermedicalscience, 2018 Apr 18; 12. PMID: 29662534    Free PMC article.
Tamoxifen Resistance Trumped and Oral Selective Estrogen Receptor Degraders Arrive.
V Craig Jordan.
Clin Cancer Res, 2018 Apr 21; 24(15). PMID: 29674510    Free PMC article.
Integration of Clinical Variables for the Prediction of Late Distant Recurrence in Patients With Estrogen Receptor-Positive Breast Cancer Treated With 5 Years of Endocrine Therapy: CTS5.
Mitch Dowsett, Ivana Sestak, +5 authors, Jack Cuzick.
J Clin Oncol, 2018 Apr 21; 36(19). PMID: 29676944    Free PMC article.
Current Status of Extended Adjuvant Endocrine Therapy in Early Stage Breast Cancer.
Irene E G van Hellemond, Sandra M E Geurts, Vivianne C G Tjan-Heijnen.
Curr Treat Options Oncol, 2018 Apr 29; 19(5). PMID: 29704066    Free PMC article.
Review.
Cardiovascular Risk in Breast Cancer Patients Receiving Estrogen or Progesterone Antagonists.
Anne H Blaes, G J van Londen, +2 authors, Daniel A Duprez.
Curr Treat Options Cardiovasc Med, 2018 May 01; 20(6). PMID: 29707737
Review.
Practical consensus recommendations on ovarian suppression in early breast cancer (adjuvant).
M Singhal, T P Sahoo, +8 authors, Purvish M Parikh.
South Asian J Cancer, 2018 May 04; 7(2). PMID: 29721484    Free PMC article.
Vinorelbine-induced regression of a choroidal metastasis from primary breast carcinoma.
Malvika Arya, Jay S Duker.
Int J Retina Vitreous, 2018 May 23; 4. PMID: 29785284    Free PMC article.
Association of Low-Fat Dietary Pattern With Breast Cancer Overall Survival: A Secondary Analysis of the Women's Health Initiative Randomized Clinical Trial.
Rowan T Chlebowski, Aaron K Aragaki, +10 authors, Ross L Prentice.
JAMA Oncol, 2018 May 26; 4(10). PMID: 29800122    Free PMC article.
Long-Term Administration of Conjugated Estrogen and Bazedoxifene Decreased Murine Fecal β-Glucuronidase Activity Without Impacting Overall Microbiome Community.
Karen Lee Ann Chen, Xiaoji Liu, +11 authors, Zeynep Madak-Erdogan.
Sci Rep, 2018 May 29; 8(1). PMID: 29802368    Free PMC article.
Talking About My Care: Detecting Mentions of Hormonal Therapy Adherence Behavior in an Online Breast Cancer Community.
Zhijun Yin, Wei Xie, Bradley A Malin.
AMIA Annu Symp Proc, 2018 Jun 02; 2017. PMID: 29854258    Free PMC article.
Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.
Prudence A Francis, Olivia Pagani, +34 authors, SOFT and TEXT Investigators and the International Breast Cancer Study Group.
N Engl J Med, 2018 Jun 05; 379(2). PMID: 29863451    Free PMC article.
Highly Cited.
Evaluation of Reproductive Concerns and Biographical Impact of Breast Cancer in Young Patients.
Maximiliane Burgmann, Kerstin Hermelink, +9 authors, Rachel Würstlein.
Breast Care (Basel), 2018 Jun 12; 13(2). PMID: 29887790    Free PMC article.
Racial and geographic disparities in adherence and discontinuation to adjuvant endocrine therapy in Texas Medicaid-insured patients with breast cancer.
Albert J Farias, Wen-Hsing Wu, Xianglin L Du.
Med Oncol, 2018 Jun 22; 35(7). PMID: 29926275    Free PMC article.
Prognostic values of the mRNA expression of natural killer receptor ligands and their association with clinicopathological features in breast cancer patients.
Ali Abouelghar, Reem Hasnah, +2 authors, Manale Karam.
Oncotarget, 2018 Jun 23; 9(43). PMID: 29930758    Free PMC article.
Should age impact breast cancer management in young women? Fine tuning of treatment guidelines.
Matteo B Suter, Olivia Pagani.
Ther Adv Med Oncol, 2018 Jul 07; 10. PMID: 29977348    Free PMC article.
Review.
Optimal management of luminal breast cancer: how much endocrine therapy is long enough?
Elisabetta Munzone, Marco Colleoni.
Ther Adv Med Oncol, 2018 Jul 07; 10. PMID: 29977350    Free PMC article.
Review.
Circulating microRNAs in the early prediction of disease recurrence in primary breast cancer.
Chara Papadaki, Michalis Stratigos, +5 authors, Sofia Agelaki.
Breast Cancer Res, 2018 Jul 13; 20(1). PMID: 29996899    Free PMC article.
Cost-effectiveness of monitoring endoxifen levels in breast cancer patients adjuvantly treated with tamoxifen.
M van Nuland, R A Vreman, +5 authors, A M Hövels.
Breast Cancer Res Treat, 2018 Jul 15; 172(1). PMID: 30006796    Free PMC article.
Determinants of non-adherence to adjuvant endocrine treatment in women with breast cancer: the role of comorbidity.
W Wulaningsih, H Garmo, +5 authors, M Lambe.
Breast Cancer Res Treat, 2018 Jul 22; 172(1). PMID: 30030708    Free PMC article.
Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells.
Andrew Sulaiman, Sarah McGarry, +16 authors, Lisheng Wang.
Cell Death Dis, 2018 Jul 28; 9(8). PMID: 30050079    Free PMC article.
A dual role of miR-22 modulated by RelA/p65 in resensitizing fulvestrant-resistant breast cancer cells to fulvestrant by targeting FOXP1 and HDAC4 and constitutive acetylation of p53 at Lys382.
Bo Wang, Dongping Li, +5 authors, Olga Kovalchuk.
Oncogenesis, 2018 Jul 31; 7(7). PMID: 30057418    Free PMC article.
The modulation of estrogen-induced apoptosis as an interpretation of the women's health initiative trials.
Balkees Abderrahman, V Craig Jordan.
Expert Rev Endocrinol Metab, 2016 Jan 01; 11(1). PMID: 30063445    Free PMC article.
Overview of Breast Cancer Therapy.
Tracy-Ann Moo, Rachel Sanford, Chau Dang, Monica Morrow.
PET Clin, 2018 Aug 14; 13(3). PMID: 30100074    Free PMC article.
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A suppressive role of guanine nucleotide-binding protein subunit beta-4 inhibited by DNA methylation in the growth of anti-estrogen resistant breast cancer cells.
Bo Wang, Dongping Li, +7 authors, Olga Kovalchuk.
BMC Cancer, 2018 Aug 15; 18(1). PMID: 30103729    Free PMC article.
Endocrine therapy for breast cancer in the primary care setting.
A Awan, K Esfahani.
Curr Oncol, 2018 Aug 17; 25(4). PMID: 30111969    Free PMC article.
SET Overexpression is Associated with Worse Recurrence-Free Survival in Patients with Primary Breast Cancer Receiving Adjuvant Tamoxifen Treatment.
Yu-Hsiang Huang, Pei-Yi Chu, +8 authors, Chun-Yu Liu.
J Clin Med, 2018 Aug 30; 7(9). PMID: 30154367    Free PMC article.
Breast cancer in adolescents and young adults.
Rebecca H Johnson, Carey K Anders, +2 authors, Archie Bleyer.
Pediatr Blood Cancer, 2018 Aug 30; 65(12). PMID: 30156052    Free PMC article.
Review.
Genomic Testing in the Management of Early-Stage Breast Cancer.
Sima Ehsani, Kari Braun Wisinski.
J Clin Outcomes Manag, 2017 May 01; 24(5). PMID: 30158821    Free PMC article.
Novel 18-gene signature for predicting relapse in ER-positive, HER2-negative breast cancer.
Richard Buus, Belinda Yeo, +7 authors, Mitch Dowsett.
Breast Cancer Res, 2018 Sep 06; 20(1). PMID: 30180877    Free PMC article.
Fertility and pregnancy in cancer survivors.
Monica Tang, Kate Webber.
Obstet Med, 2018 Sep 15; 11(3). PMID: 30214475    Free PMC article.
Review.
Impact of hormonal therapy and other adjuvant therapies on contralateral breast volume change after implant-based breast reconstruction.
Jung Youl Park, Jae-Ho Chung, +3 authors, Eul-Sik Yoon.
Arch Plast Surg, 2018 Oct 05; 45(5). PMID: 30282414    Free PMC article.
Rising Incidence of Breast Cancer in the Young Fertile Indian Population-a Reality Check.
Vani Parmar.
Indian J Surg Oncol, 2018 Oct 06; 9(3). PMID: 30287986    Free PMC article.
Clinical outcomes comparison of 10 years versus 5 years of adjuvant endocrine therapy in patients with early breast cancer.
Li Li, Bingmei Chang, +7 authors, Qin Li.
BMC Cancer, 2018 Oct 14; 18(1). PMID: 30314452    Free PMC article.
Co-expression of nuclear P38 and hormone receptors is prognostic of good long-term clinical outcome in primary breast cancer and is linked to upregulation of DNA repair.
Simon J Johnston, Dena Ahmad, +5 authors, Emad A Rakha.
BMC Cancer, 2018 Oct 26; 18(1). PMID: 30352570    Free PMC article.
Improving adherence to endocrine hormonal therapy among breast cancer patients: Study protocol for a randomized controlled trial.
P Chalela, E Munoz, +5 authors, A Ramirez.
Contemp Clin Trials Commun, 2018 Nov 01; 12. PMID: 30377674    Free PMC article.
The Value of Monitoring the Behavior of Circulating Tumor Cells at the End of Endocrine Therapy in Breast Cancer Patients.
Katharina Pachmann, Stefan Schuster.
Cancers (Basel), 2018 Nov 02; 10(11). PMID: 30380648    Free PMC article.
Expression of the CD59 Glycoprotein Precursor is Upregulated in an Estrogen Receptor-alpha (ER-α)-Negative and a Tamoxifen-Resistant Breast Cancer Cell Line In Vitro.
Huiru Xiong, Xiaowei Jin, Chuanwen You.
Med Sci Monit, 2018 Nov 06; 24. PMID: 30391994    Free PMC article.
Lymph node metastasis and high serum CEA are important prognostic factors in hormone receptor positive and HER2 negative breast cancer.
Yoshimasa Kosaka, Naoko Minatani, +10 authors, Masahiko Watanabe.
Mol Clin Oncol, 2018 Nov 08; 9(5). PMID: 30402236    Free PMC article.
Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer.
Yoshikazu Johmura, Ichiro Maeda, +17 authors, Makoto Nakanishi.
J Clin Invest, 2018 Nov 13; 128(12). PMID: 30418174    Free PMC article.
Is Monitoring Mean Platelet Volume Necessary in Breast Cancer Patients?
Halil Taskaynatan, Ahmet Alacacioglu, +5 authors, Mustafa Oktay Tarhan.
Open Med (Wars), 2018 Nov 15; 13. PMID: 30426082    Free PMC article.
Extended duration of adjuvant aromatase inhibitor in breast cancer: a meta-analysis of randomized controlled trials.
Zackariah Clement, James Kollias, +2 authors, Melissa Bochner.
Gland Surg, 2018 Dec 07; 7(5). PMID: 30505766    Free PMC article.
Mortality after breast cancer as a function of time since diagnosis by estrogen receptor status and age at diagnosis.
Harindra Jayasekara, Robert J MacInnis, +11 authors, John L Hopper.
Int J Cancer, 2019 Feb 17; 145(12). PMID: 30771221    Free PMC article.
Simulating Time-Dependent Patterns of Nonadherence by Patients With Breast Cancer to Adjuvant Oral Endocrine Therapy.
Eileen H Shinn, Gordon Broderick, +4 authors, William Fraser Symmans.
JCO Clin Cancer Inform, 2019 Apr 20; 3. PMID: 31002563    Free PMC article.
Activated zinc transporter ZIP7 as an indicator of anti-hormone resistance in breast cancer.
Silvia Ziliotto, Julia M W Gee, +4 authors, Kathryn M Taylor.
Metallomics, 2019 Sep 05; 11(9). PMID: 31483418    Free PMC article.
Triple-Negative Breast Cancer: Current Understanding and Future Therapeutic Breakthrough Targeting Cancer Stemness.
Kha-Liang Lee, Yung-Che Kuo, Yuan-Soon Ho, Yen-Hua Huang.
Cancers (Basel), 2019 Sep 12; 11(9). PMID: 31505803    Free PMC article.
Highly Cited. Review.
ERα-targeted endocrine therapy, resistance and the role of GPER.
Richard A Pepermans, Eric R Prossnitz.
Steroids, 2019 Sep 14; 152. PMID: 31518595    Free PMC article.
Review.
Prediction of Late Breast Cancer-Specific Mortality in Recurrence-Free Breast Cancer Survivors Treated for Five Years with Tamoxifen.
Soo Yeon Baek, Ji Yeong Kwon, +12 authors, Jong Won Lee.
J Breast Cancer, 2019 Oct 11; 22(3). PMID: 31598339    Free PMC article.
Breast Cancer Stem Cells as Drivers of Tumor Chemoresistance, Dormancy and Relapse: New Challenges and Therapeutic Opportunities.
Maria Laura De Angelis, Federica Francescangeli, Ann Zeuner.
Cancers (Basel), 2019 Oct 18; 11(10). PMID: 31619007    Free PMC article.
Review.
Incidence of Late Relapses in Patients With HER2-Positive Breast Cancer Receiving Adjuvant Trastuzumab: Combined Analysis of NCCTG N9831 (Alliance) and NRG Oncology/NSABP B-31.
Saranya Chumsri, Zhuo Li, +9 authors, E Aubrey Thompson.
J Clin Oncol, 2019 Oct 18; 37(35). PMID: 31622131    Free PMC article.
Is Tamoxifen Use a Factor Affecting Continence in Breast Cancer Patients?
Goksen Inanc Imamoglu, Tulay Eren, +3 authors, Burhan Baylan.
Cureus, 2019 Oct 22; 11(8). PMID: 31632870    Free PMC article.
The duration of endocrine therapy and breast cancer patients' survival: A nationwide population-based cohort study.
Chuan-Hsun Chang, Chun-Wen Huang, +3 authors, You-Min Lu.
Medicine (Baltimore), 2019 Oct 28; 98(43). PMID: 31651908    Free PMC article.
Update Breast Cancer 2019 Part 4 - Diagnostic and Therapeutic Challenges of New, Personalised Therapies for Patients with Early Breast Cancer.
Florian Schütz, Peter A Fasching, +16 authors, Volkmar Müller.
Geburtshilfe Frauenheilkd, 2019 Oct 28; 79(10). PMID: 31656318    Free PMC article.
Increasing Adherence to Adjuvant Hormone Therapy Among Patients With Breast Cancer: A Smart Phone App-Based Pilot Study.
Jessica L Krok-Schoen, Michelle J Naughton, +7 authors, Douglas M Post.
Cancer Control, 2019 Nov 19; 26(1). PMID: 31736324    Free PMC article.
The "1-year-death number needed to treat" for comparing the impact of distinct interventions on patient outcomes.
Brett N Hryciw, Finlay A McAlister, Meltem Tuna, Carl van Walraven.
CMAJ, 2019 Nov 13; 191(45). PMID: 31712358    Free PMC article.
Detection of disseminated tumor cells in bone marrow predict late recurrences in operable breast cancer patients.
Kjersti Tjensvoll, Oddmund Nordgård, +3 authors, Bjørnar Gilje.
BMC Cancer, 2019 Nov 23; 19(1). PMID: 31752747    Free PMC article.
iRGD-guided tamoxifen polymersomes inhibit estrogen receptor transcriptional activity and decrease the number of breast cancer cells with self-renewing capacity.
María Inés Diaz Bessone, Lorena Simón-Gracia, +4 authors, Marina Simian.
J Nanobiotechnology, 2019 Dec 10; 17(1). PMID: 31812165    Free PMC article.
New insights into acquired endocrine resistance of breast cancer.
Ping Fan, V Craig Jordan.
Cancer Drug Resist, 2019 Dec 10; 2. PMID: 31815253    Free PMC article.
Progesterone induces cell apoptosis via the CACNA2D3/Ca2+/p38 MAPK pathway in endometrial cancer.
Xiangnan Kong, Min Li, +3 authors, Meijuan Cai.
Oncol Rep, 2019 Nov 21; 43(1). PMID: 31746409    Free PMC article.
Counseling young women with early breast cancer on fertility preservation.
M E Elena Ter Welle-Butalid, I J H Ingeborg Vriens, +5 authors, V C G Vivianne Tjan-Heijnen.
J Assist Reprod Genet, 2019 Nov 25; 36(12). PMID: 31760547    Free PMC article.
Breast Cancer Index and prediction of benefit from extended endocrine therapy in breast cancer patients treated in the Adjuvant Tamoxifen-To Offer More? (aTTom) trial.
J M S Bartlett, D C Sgroi, +8 authors, D W Rea.
Ann Oncol, 2019 Sep 11; 30(11). PMID: 31504126    Free PMC article.
Endocrine-responsive lobular carcinoma of the breast: features associated with risk of late distant recurrence.
Fabio Conforti, Laura Pala, +12 authors, Aron Goldhirsch.
Breast Cancer Res, 2020 Jan 01; 21(1). PMID: 31888717    Free PMC article.
Downregulation of CXXC Finger Protein 4 Leads to a Tamoxifen-resistant Phenotype in Breast Cancer Cells Through Activation of the Wnt/β-catenin Pathway.
Yijie Fu, Zhu Wang, +4 authors, Hong Zheng.
Transl Oncol, 2020 Jan 09; 13(2). PMID: 31911277    Free PMC article.
Renalase overexpression in ER-positive breast cancer.
Xuewen Yu, Pengxun Han, +2 authors, Mumin Shao.
Int J Clin Exp Pathol, 2018 Mar 01; 11(3). PMID: 31938225    Free PMC article.
Successful Targeted Therapies for Breast Cancer: the Worcester Foundation and Future Opportunities in Women's Health.
Balkees Abderrahman, V Craig Jordan.
Endocrinology, 2018 Jun 23; 159(8). PMID: 29931061    Free PMC article.
Review.
Preexisting Commensal Dysbiosis Is a Host-Intrinsic Regulator of Tissue Inflammation and Tumor Cell Dissemination in Hormone Receptor-Positive Breast Cancer.
Claire Buchta Rosean, Raegan R Bostic, +7 authors, Melanie R Rutkowski.
Cancer Res, 2019 May 09; 79(14). PMID: 31064848    Free PMC article.
Society for Translational Medicine consensus on postoperative management of EGFR-mutant lung cancer (2019 edition).
Wenhua Liang, Kaican Cai, +57 authors, AME Thoracic Surgery Collaborative Group.
Transl Lung Cancer Res, 2020 Feb 06; 8(6). PMID: 32010594    Free PMC article.
Review.
ERα36 as a Potential Therapeutic Target for Tamoxifen-Resistant Breast Cancer Cell Line Through EGFR/ERK Signaling Pathway.
Guangliang Li, Jing Zhang, Zhenzhen Xu, Zhongqi Li.
Cancer Manag Res, 2020 Feb 06; 12. PMID: 32021441    Free PMC article.
Providers' Perspectives on Adherence to Hormonal Therapy in Breast Cancer Survivors. Is there a Role for the Digital Health Feedback System?
Alejandra Hurtado de Mendoza, Mark Cabling, +6 authors, Vanessa B Sheppard.
Health Technol (Berl), 2019 Aug 27; 9(2). PMID: 31448187    Free PMC article.
Are large simple trials for dementia prevention possible?
William N Whiteley, Sonia Anand, +15 authors, Salim Yusuf.
Age Ageing, 2019 Dec 13; 49(2). PMID: 31830268    Free PMC article.
Suitable trial designs and cohorts for preventive breast cancer agents.
Kathrin Strasser-Weippl, Paul E Goss.
Nat Rev Clin Oncol, 2013 Oct 09; 10(12). PMID: 24101120
Review.
Association of Circulating Tumor Cells With Late Recurrence of Estrogen Receptor-Positive Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial.
Joseph Sparano, Anne O'Neill, +5 authors, Kathy D Miller.
JAMA Oncol, 2018 Jul 29; 4(12). PMID: 30054636    Free PMC article.
Highly Cited.
SELECT: A Phase II Trial of Adjuvant Erlotinib in Patients With Resected Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer.
Nathan A Pennell, Joel W Neal, +14 authors, Lecia V Sequist.
J Clin Oncol, 2018 Nov 18; 37(2). PMID: 30444685    Free PMC article.
Testing a behavioral intervention to improve adherence to adjuvant endocrine therapy (AET).
Rebecca A Shelby, Caroline S Dorfman, +12 authors, Gretchen Kimmick.
Contemp Clin Trials, 2018 Nov 26; 76. PMID: 30472215    Free PMC article.
Risk and prognostic factors for endometrial carcinoma after diagnosis of breast or Lynch-associated cancers-A population-based analysis.
Sharon E Johnatty, Colin J R Stewart, +6 authors, Amanda B Spurdle.
Cancer Med, 2018 Nov 30; 7(12). PMID: 30485707    Free PMC article.
Efficacy of anastrozole after tamoxifen in early breast cancer patients with chemotherapy-induced ovarian function failure.
Irene E G van Hellemond, Ingeborg J H Vriens, +15 authors, Dutch Breast Cancer Research Group (BOOG).
Int J Cancer, 2018 Dec 28; 145(1). PMID: 30588619    Free PMC article.
Mission-oriented translational cancer research - health economics.
Bengt Jönsson, Richard Sullivan.
Mol Oncol, 2019 Jan 11; 13(3). PMID: 30628161    Free PMC article.
Review.
Sex hormones and stroke: Beyond estrogens.
Farida Sohrabji, Andre Okoreeh, Aditya Panta.
Horm Behav, 2019 Feb 05; 111. PMID: 30713101    Free PMC article.
Review.
Estrogens and breast cancer: Mechanisms involved in obesity-related development, growth and progression.
Priya Bhardwaj, CheukMan C Au, +4 authors, Kristy A Brown.
J Steroid Biochem Mol Biol, 2019 Mar 10; 189. PMID: 30851382    Free PMC article.
Review.
Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.
Oscar M Rueda, Stephen-John Sammut, +21 authors, Christina Curtis.
Nature, 2019 Mar 15; 567(7748). PMID: 30867590    Free PMC article.
Highly Cited.
Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes.
Marcelo Sobral-Leite, Izhar Salomon, +13 authors, Marleen Kok.
Breast Cancer Res, 2019 Aug 09; 21(1). PMID: 31391067    Free PMC article.
Assessment of Relative Utility of Underlying vs Contributory Causes of Death.
G David Batty, Catharine R Gale, Mika Kivimäki, Steven Bell.
JAMA Netw Open, 2019 Aug 01; 2(7). PMID: 31365105    Free PMC article.
Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer.
Teodora Costea, Oana Cezara Vlad, +3 authors, Maria-Magdalena Mocanu.
Int J Mol Sci, 2020 Jan 16; 21(2). PMID: 31936346    Free PMC article.
Review.
Tamoxifen-related endocrine symptoms in Chinese patients with breast cancer: Study protocol clinical trial (SPIRIT Compliant).
Carmen Wing Han Chan, Christine Miaskowski, +6 authors, Judy Yuet Wa Chan.
Medicine (Baltimore), 2020 Feb 23; 99(8). PMID: 32080081    Free PMC article.
Impact of preexisting mental illness on breast cancer endocrine therapy adherence.
Cole B Haskins, Bradley D McDowell, +4 authors, Elizabeth A Chrischilles.
Breast Cancer Res Treat, 2018 Nov 23; 174(1). PMID: 30465157    Free PMC article.
Partner status moderates the relationships between sexual problems and self-efficacy for managing sexual problems and psychosocial quality-of-life for postmenopausal breast cancer survivors taking adjuvant endocrine therapy.
Caroline S Dorfman, Sarah S Arthur, +5 authors, Rebecca A Shelby.
Menopause, 2019 Apr 18; 26(8). PMID: 30994574    Free PMC article.
Depomedroxyprogesterone acetate therapy for hot flashes in survivors of breast cancer: no unfavorable impact on recurrence and survival.
Natalie M Ertz-Archambault, Lana B Rogoff, +5 authors, Donald W Northfelt.
Support Care Cancer, 2019 Aug 14; 28(5). PMID: 31402403
Validation of CTS5 model in large-scale breast cancer population and the impact of menopausal and HER2 status on its prognostic value.
Changjun Wang, Chang Chen, +10 authors, Qiang Sun.
Sci Rep, 2020 Mar 15; 10(1). PMID: 32170181    Free PMC article.
Effects of Previous Medication Regimen Factors and Bipolar and Psychotic Disorders on Breast Cancer Endocrine Therapy Adherence.
Cole B Haskins, Joan M Neuner, +5 authors, Elizabeth A Chrischilles.
Clin Breast Cancer, 2020 Mar 07; 20(3). PMID: 32139273    Free PMC article.
Breast cancer metastasis to gynaecological organs: a clinico-pathological and molecular profiling study.
Jamie R Kutasovic, Amy E McCart Reed, +16 authors, Peter T Simpson.
J Pathol Clin Res, 2018 Sep 25; 5(1). PMID: 30246500    Free PMC article.
Adherence and Persistence to Adjuvant Hormonal Therapy in Early-Stage Breast Cancer Patients: A Population-Based Retrospective Cohort Study in Israel.
Tal Sella, Gabriel Chodick.
Breast Care (Basel), 2020 Apr 02; 15(1). PMID: 32231497    Free PMC article.
Use of letrozole after aromatase inhibitor-based therapy in postmenopausal breast cancer (NRG Oncology/NSABP B-42): a randomised, double-blind, placebo-controlled, phase 3 trial.
Eleftherios P Mamounas, Hanna Bandos, +17 authors, Norman Wolmark.
Lancet Oncol, 2018 Dec 05; 20(1). PMID: 30509771    Free PMC article.
Drug repurposing for breast cancer therapy: Old weapon for new battle.
Sadhna Aggarwal, Sumit Singh Verma, Sumit Aggarwal, Subash Chandra Gupta.
Semin Cancer Biol, 2019 Sep 25; 68. PMID: 31550502    Free PMC article.
Review.
Risk Factors Associated with Endometrial Pathology in Premenopausal Breast Cancer Patients Treated with Tamoxifen.
Maria Lee, Jinlan Piao, Myung Jae Jeon.
Yonsei Med J, 2020 Apr 02; 61(4). PMID: 32233174    Free PMC article.
Review.
Effect of Tamoxifen on the Risk of Osteoporosis and Osteoporotic Fracture in Younger Breast Cancer Survivors: A Nationwide Study.
Jihyoun Lee, Heba M Alqudaihi, +11 authors, Il Yong Chung.
Front Oncol, 2020 Apr 09; 10. PMID: 32266146    Free PMC article.
Younger tamoxifen-treated breast cancer patients also had higher risk of endometrial cancer and the risk could be reduced by sequenced aromatase inhibitor use: A population-based study in Taiwan.
Sung-Chao Chu, Chia-Jung Hsieh, +2 authors, Tang-Yuan Chu.
Ci Ji Yi Xue Za Zhi, 2020 Apr 10; 32(2). PMID: 32269951    Free PMC article.
Metastatic Latency, a Veiled Threat.
Kangsan Kim, Mauricio Marquez-Palencia, Srinivas Malladi.
Front Immunol, 2019 Aug 27; 10. PMID: 31447846    Free PMC article.
Review.
Integrated Data Analysis of Six Clinical Studies Points Toward Model-Informed Precision Dosing of Tamoxifen.
Lena Klopp-Schulze, Anna Mueller-Schoell, +4 authors, Charlotte Kloft.
Front Pharmacol, 2020 Apr 17; 11. PMID: 32296331    Free PMC article.
Treatment times in breast cancer patients receiving neoadjuvant vs adjuvant chemotherapy: Is efficiency a benefit of preoperative chemotherapy?
Nicole M Melchior, Darren B Sachs, +8 authors, Richard J Bleicher.
Cancer Med, 2020 Feb 26; 9(8). PMID: 32096915    Free PMC article.
Cancer Vaccines and Oncolytic Viruses Exert Profoundly Lower Side Effects in Cancer Patients than Other Systemic Therapies: A Comparative Analysis.
Volker Schirrmacher.
Biomedicines, 2020 Mar 20; 8(3). PMID: 32188078    Free PMC article.
Review.
Patient Messaging Content Associated with Initiating Hormonal Therapy after a Breast Cancer Diagnosis.
Zhijun Yin, Jeremy L Warner, Qingxia Chen, Bradley A Malin.
AMIA Annu Symp Proc, 2020 Apr 21; 2019. PMID: 32308893    Free PMC article.
Double Trouble: Contralateral Breast Cancer Risk Management in the Modern Era.
Kevin J Cheung, Nancy E Davidson.
J Natl Cancer Inst, 2019 Jan 31; 111(7). PMID: 30698728    Free PMC article.
Issues with Fertility in Young Women with Breast Cancer.
Nicole Christian, Mary L Gemignani.
Curr Oncol Rep, 2019 May 18; 21(7). PMID: 31098718
Review.
Novel Tamoxifen Nanoformulations for Improving Breast Cancer Treatment: Old Wine in New Bottles.
Candace M Day, Shane M Hickey, +2 authors, Sanjay Garg.
Molecules, 2020 Mar 11; 25(5). PMID: 32151063    Free PMC article.
Review.
Factors Associated with Endocrine Therapy Non-Adherence in Breast Cancer Survivors.
Jennifer C Spencer, Bryce B Reeve, Melissa A Troester, Stephanie B Wheeler.
Psychooncology, 2020 Feb 13; 29(4). PMID: 32048400    Free PMC article.
Outcomes of ovarian stimulation and fertility preservation in breast cancer patients with different hormonal receptor profiles.
Jacques Balayla, Togas Tulandi, +4 authors, Alexander Volodarsky-Perel.
J Assist Reprod Genet, 2020 Mar 08; 37(4). PMID: 32144524    Free PMC article.
Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 1: Late Recurrence: Current Understanding, Clinical Considerations.
Ryan J O Dowling, Kevin Kalinsky, +29 authors, Pamela J Goodwin.
JNCI Cancer Spectr, 2020 Apr 28; 3(4). PMID: 32337479    Free PMC article.
Estrogen receptor mutations found in breast cancer metastases integrated with the molecular pharmacology of selective ER modulators.
V Craig Jordan, Ramona Curpan, Philipp Y Maximov.
J Natl Cancer Inst, 2015 Apr 04; 107(6). PMID: 25838462    Free PMC article.
PD-L1 expression is a predictive biomarker for CIK cell-based immunotherapy in postoperative patients with breast cancer.
Zi-Qi Zhou, Jing-Jing Zhao, +6 authors, Jian-Chuan Xia.
J Immunother Cancer, 2019 Aug 29; 7(1). PMID: 31455411    Free PMC article.
The Role of Circulating Tumor Cells in the Metastatic Cascade: Biology, Technical Challenges, and Clinical Relevance.
Hassan Dianat-Moghadam, Mehdi Azizi, +4 authors, Catherine Alix-Panabières.
Cancers (Basel), 2020 Apr 09; 12(4). PMID: 32260071    Free PMC article.
Review.
Breast Cancer: Lifestyle, the Human Gut Microbiota/Microbiome, and Survivorship.
Balazs I Bodai, Therese E Nakata.
Perm J, 2020 Jun 27; 24. PMID: 32589577    Free PMC article.
Breast cancer: are long-term and intermittent endocrine therapies equally effective?
Jutta Engel, Gabriele Schubert-Fritschle, Rebecca Emeny, Dieter Hölzel.
J Cancer Res Clin Oncol, 2020 May 31; 146(8). PMID: 32472445    Free PMC article.
Review.
A prospective, randomized study of Toremifene vs. tamoxifen for the treatment of premenopausal breast cancer: safety and genital symptom analysis.
Jin Hong, Jiahui Huang, +10 authors, Kunwei Shen.
BMC Cancer, 2020 Jul 18; 20(1). PMID: 32677982    Free PMC article.
Computer-Aided Ligand Discovery for Estrogen Receptor Alpha.
Divya Bafna, Fuqiang Ban, +2 authors, Artem Cherkasov.
Int J Mol Sci, 2020 Jun 18; 21(12). PMID: 32545494    Free PMC article.
Review.
Management of hormone receptor-positive, HER2-negative early breast cancer.
Elaine M Walsh, Karen L Smith, Vered Stearns.
Semin Oncol, 2020 Jun 18; 47(4). PMID: 32546323    Free PMC article.
Review.
Endocrine Therapy for Breast Cancer: A Model of Hormonal Manipulation.
Simon J Johnston, Kwok-Leung Cheung.
Oncol Ther, 2018 Dec 01; 6(2). PMID: 32700026    Free PMC article.
Review.
Fertility in Breast Cancer Survivors in the Middle East: A Retrospective Study.
Hazem I Assi, Rasha T Kakati, +8 authors, Nagi El Saghir.
Breast, 2020 May 11; 52. PMID: 32388348    Free PMC article.
Risk of fatty liver after long-term use of tamoxifen in patients with breast cancer.
Jeong-Ju Yoo, Yong Seok Lim, +7 authors, Young Seok Kim.
PLoS One, 2020 Jul 31; 15(7). PMID: 32730287    Free PMC article.
FBXO22, an epigenetic multiplayer coordinating senescence, hormone signaling, and metastasis.
Yoshikazu Johmura, Alexander S Harris, Tomohiko Ohta, Makoto Nakanishi.
Cancer Sci, 2020 Jun 15; 111(8). PMID: 32536008    Free PMC article.
Review.
Digital Image Analysis of Ki-67 Stained Tissue Microarrays and Recurrence in Tamoxifen-Treated Breast Cancer Patients.
Nina Gran Egeland, Kristin Jonsdottir, +7 authors, Emiel A M Janssen.
Clin Epidemiol, 2020 Aug 18; 12. PMID: 32801916    Free PMC article.
To Treat or Not to Treat: The Use of Hormone Replacement Therapy in Patients With Ovarian Cancer.
Stanley Lipkowitz, Elise C Kohn.
J Clin Oncol, 2015 Oct 07; 33(35). PMID: 26438113    Free PMC article.
Endocrine Risk Factors of Endometrial Cancer: Polycystic Ovary Syndrome, Oral Contraceptives, Infertility, Tamoxifen.
Atanas Ignatov, Olaf Ortmann.
Cancers (Basel), 2020 Jul 08; 12(7). PMID: 32630728    Free PMC article.
Review.
Tamoxifen Induced Pachychoroid Pigment Epitheliopathy with Reversible Changes After Drug Discontinuation.
Fariba Ghassemi, Babak Masoomian, +3 authors, Hamid Riazi-Esfahani.
Int Med Case Rep J, 2020 Sep 05; 13. PMID: 32884364    Free PMC article.
Adjuvant therapies after curative treatments for hepatocellular carcinoma: Current status and prospects.
Xiao-Dong Zhu, Kang-Shuai Li, Hui-Chuan Sun.
Genes Dis, 2020 Sep 05; 7(3). PMID: 32884990    Free PMC article.
Review.
Stabilization of MORC2 by estrogen and antiestrogens through GPER1- PRKACA-CMA pathway contributes to estrogen-induced proliferation and endocrine resistance of breast cancer cells.
Fan Yang, Hong-Yan Xie, +5 authors, Zhi-Ming Shao.
Autophagy, 2020 May 14; 16(6). PMID: 32401166    Free PMC article.
Application of the ESMO-Magnitude of Clinical Benefit Scale (V.1.1) to the field of early breast cancer therapies.
Shani Paluch-Shimon, Nathan I Cherny, +4 authors, Fatima Cardoso.
ESMO Open, 2020 Sep 08; 5(5). PMID: 32893189    Free PMC article.
Precautions for Patients Taking Tamoxifen.
Mary Heery, Patrick Corbett, Richard Zelkowitz.
J Adv Pract Oncol, 2018 Dec 20; 9(1). PMID: 30564470    Free PMC article.
Review.
Therapeutic advances in hormone-dependent cancers: focus on prostate, breast and ovarian cancers.
Michael Ulm, Arvind V Ramesh, +3 authors, Ramesh Narayanan.
Endocr Connect, 2019 Jan 15; 8(2). PMID: 30640710    Free PMC article.
Review.
A combination of the PI3K pathway inhibitor plus cell cycle pathway inhibitor to combat endocrine resistance in hormone receptor-positive breast cancer: a genomic algorithm-based treatment approach.
Anita Gul, Brain Leyland-Jones, Nandini Dey, Pradip De.
Am J Cancer Res, 2019 Jan 22; 8(12). PMID: 30662797    Free PMC article.
Review.
Prognostic Factors of Local-Regional Recurrence in Patients with Operable Breast Cancer in Asia: A Meta-Analysis.
Wirsma Arif Harahap, Ricvan Dana Nindrea.
Open Access Maced J Med Sci, 2019 Mar 22; 7(4). PMID: 30894935    Free PMC article.
Review.
Prescription Refill Gap of Endocrine Treatment from Electronic Medical Records as a Prognostic Factor in Breast Cancer Patients.
Yura Lee, Yu Rang Park, +5 authors, Jong Won Lee.
J Breast Cancer, 2019 Apr 04; 22(1). PMID: 30941236    Free PMC article.
Young Patients with Hormone Receptor-Positive Breast Cancer Have a Higher Long-Term Risk of Breast Cancer Specific Death.
Jianfei Fu, Chenhan Zhong, +5 authors, Jinlin Du.
J Breast Cancer, 2019 Apr 04; 22(1). PMID: 30941237    Free PMC article.
Detarium microcarpum, Guiera senegalensis, and Cassia siamea Induce Apoptosis and Cell Cycle Arrest and Inhibit Metastasis on MCF7 Breast Cancer Cells.
Ismail Abiola Adebayo, Haladu Ali Gagman, +6 authors, Hasni Arsad.
Evid Based Complement Alternat Med, 2019 Jun 27; 2019. PMID: 31239861    Free PMC article.
Long-Term Use of Tamoxifen Is Associated With a Decreased Subsequent Meningioma Risk in Patients With Breast Cancer: A Nationwide Population-Based Cohort Study.
Li-Min Sun, Cheng-Li Lin, +3 authors, Chia-Hung Kao.
Front Pharmacol, 2019 Jun 30; 10. PMID: 31249531    Free PMC article.
The potential influence of breast cancer estrogen receptors' distribution on active DNA demethylation.
Kinga Linowiecka, Olga Urbanowska-Domańska, Jolanta Guz, Marek Foksiński.
Contemp Oncol (Pozn), 2019 Jul 19; 23(2). PMID: 31316288    Free PMC article.
Review.
Potential Mechanisms of Age Acceleration Caused by Estrogen Deprivation: Do Endocrine Therapies Carry the Same Risks?
Mary E Sehl, Patricia A Ganz.
JNCI Cancer Spectr, 2019 Jul 31; 2(3). PMID: 31360862    Free PMC article.
Review.
Bisphosphonates and primary breast cancer risk: an updated systematic review and meta-analysis involving 963,995 women.
Yupeng Liu, Xiaosan Zhang, +5 authors, Yashuang Zhao.
Clin Epidemiol, 2019 Aug 15; 11. PMID: 31410067    Free PMC article.
Decreasing secondary primary uterine cancer after breast cancer: A population-based analysis.
Koji Matsuo, Rachel S Mandelbaum, +4 authors, Jason D Wright.
Gynecol Oncol, 2019 May 28; 154(1). PMID: 31130286    Free PMC article.
Tumor characteristics and survival outcomes of women with tamoxifen-related uterine carcinosarcoma.
Koji Matsuo, Malcolm S Ross, +28 authors, Lynda D Roman.
Gynecol Oncol, 2016 Dec 10; 144(2). PMID: 27931750    Free PMC article.
Endocrine Therapy in Early Breast Cancer.
Katja Krauss, Elmar Stickeler.
Breast Care (Basel), 2020 Sep 29; 15(4). PMID: 32982643    Free PMC article.
Review.
Do we still need breast cancer screening in the era of targeted therapies and precision medicine?
Rubina Manuela Trimboli, Paolo Giorgi Rossi, +4 authors, Francesco Sardanelli.
Insights Imaging, 2020 Sep 26; 11(1). PMID: 32975658    Free PMC article.
Review.
Does Use of Neoadjuvant Chemotherapy Affect the Decision to Pursue Fertility Preservation Options in Young Women with Breast Cancer?
Angelena Crown, Shirin Muhsen, +4 authors, Mary L Gemignani.
Ann Surg Oncol, 2020 Aug 09; 27(12). PMID: 32767225    Free PMC article.
Adherence to adjuvant endocrine therapy among breast cancer survivors: a systematic review and meta-synthesis of the qualitative literature using grounded theory.
Othman AlOmeir, Nilesh Patel, Parastou Donyai.
Support Care Cancer, 2020 Jul 01; 28(11). PMID: 32601852    Free PMC article.
Systematic Review.
Tamoxifen and Endometrial Cancer: A Janus-Headed Drug.
Günter Emons, Alexander Mustea, Clemens Tempfer.
Cancers (Basel), 2020 Sep 11; 12(9). PMID: 32906618    Free PMC article.
Review.
Outcomes for Patients with Residual Stage II/III Breast Cancer Following Neoadjuvant Chemotherapy (AFT-01).
T J Stankowski-Drengler, J R Schumacher, +5 authors, H B Neuman.
Ann Surg Oncol, 2020 Jan 05; 27(3). PMID: 31900808    Free PMC article.
Transcription Factors in Cartilage Homeostasis and Osteoarthritis.
Margot Neefjes, Arjan P M van Caam, Peter M van der Kraan.
Biology (Basel), 2020 Sep 18; 9(9). PMID: 32937960    Free PMC article.
Review.
Breast Cancer and Tamoxifen: A Nigerian Perspective to Effective Personalised Therapy.
Ayorinde Adehin, Martin Alexander Kennedy, +3 authors, Oluseye Oladotun Bolaji.
Breast Cancer (Dove Med Press), 2020 Oct 30; 12. PMID: 33116814    Free PMC article.
Review.
Genome-wide analysis of therapeutic response uncovers molecular pathways governing tamoxifen resistance in ER+ breast cancer.
Sarra M Rahem, Nusrat J Epsi, Frederick D Coffman, Antonina Mitrofanova.
EBioMedicine, 2020 Oct 26; 61. PMID: 33099086    Free PMC article.
Validation of Clinical Treatment Score post-5 years (CTS5) risk stratification in premenopausal breast cancer patients and Ki-67 labelling index.
Janghee Lee, Chihwan Cha, +9 authors, Joon Jeong.
Sci Rep, 2020 Oct 10; 10(1). PMID: 33033359    Free PMC article.
Clinical Implications of Serum 25-Hydroxyvitamin D Status after 5-Year Adjuvant Endocrine Therapy for Late Recurrence of Hormone Receptor-positive Breast Cancer.
Seung Taek Lim, Ye Won Jeon, Hongki Gwak, Young Jin Suh.
J Breast Cancer, 2020 Nov 07; 23(5). PMID: 33154825    Free PMC article.
Time-Resolved Profiling Reveals ATF3 as a Novel Mediator of Endocrine Resistance in Breast Cancer.
Simone Borgoni, Emre Sofyalı, +11 authors, Stefan Wiemann.
Cancers (Basel), 2020 Oct 15; 12(10). PMID: 33050633    Free PMC article.
Landmark trials in the medical oncology management of early stage breast cancer.
Whitney Hensing, Cesar A Santa-Maria, Lindsay L Peterson, Jennifer Y Sheng.
Semin Oncol, 2020 Sep 17; 47(5). PMID: 32933761    Free PMC article.
Review.
Tuning Cancer Fate: Tumor Microenvironment's Role in Cancer Stem Cell Quiescence and Reawakening.
Antonella Sistigu, Martina Musella, +2 authors, Ruggero De Maria.
Front Immunol, 2020 Nov 17; 11. PMID: 33193295    Free PMC article.
Review.
The therapy is making me sick: how online portal communications between breast cancer patients and physicians indicate medication discontinuation.
Zhijun Yin, Morgan Harrell, +3 authors, Bradley A Malin.
J Am Med Inform Assoc, 2018 Nov 01; 25(11). PMID: 30380083    Free PMC article.
Endocrine Therapy in Premenopausal Hormone Receptor-Positive Breast Cancer.
Amye J Tevaarwerk, Kari B Wisinski, Ruth M O'Regan.
J Oncol Pract, 2016 Nov 20; 12(11). PMID: 27858538    Free PMC article.
Review.
Managerial Self-Efficacy for Chemotherapy-Related Symptoms and Related Risk Factors in Women with Breast Cancer
Fatemeh Moghaddam Tabrizi, Saeedeh Alizadeh, Samira Barjasteh.
Asian Pac J Cancer Prev, 2017 Jul 04; 18(6). PMID: 28669166    Free PMC article.
SEOM clinical guidelines in early stage breast cancer (2018).
F Ayala de la Peña, R Andrés, +7 authors, E Ciruelos.
Clin Transl Oncol, 2018 Nov 18; 21(1). PMID: 30443868    Free PMC article.
Multi-drug resistance protein 2 (MRP2) expression, adjuvant tamoxifen therapy, and risk of breast cancer recurrence: a Danish population-based nested case-control study.
Cathrine F Hjorth, Anja S Nielsen, +4 authors, Deirdre Cronin-Fenton.
Acta Oncol, 2018 Nov 22; 58(2). PMID: 30458661    Free PMC article.
CYP2D6-inhibiting medication use and inherited CYP2D6 variation in relation to adverse breast cancer outcomes after tamoxifen therapy.
Sophie E Mayer, Noel S Weiss, +5 authors, Kathleen E Malone.
Cancer Causes Control, 2018 Dec 14; 30(1). PMID: 30542984    Free PMC article.
Examination of a paradox: recurrent metastatic breast cancer incidence decline without improved distant disease survival: 1990-2011.
Judith Malmgren, Marc Hurlbert, Mary Atwood, Henry G Kaplan.
Breast Cancer Res Treat, 2018 Dec 19; 174(2). PMID: 30560462    Free PMC article.
Dormancy in cancer.
Hiroko Endo, Masahiro Inoue.
Cancer Sci, 2018 Dec 24; 110(2). PMID: 30575231    Free PMC article.
Review.
Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) - Part 2 with Recommendations for the Therapy of Primary, Recurrent and Advanced Breast Cancer.
Achim Wöckel, Jasmin Festl, +94 authors, Stephanie Stangl.
Geburtshilfe Frauenheilkd, 2018 Dec 26; 78(11). PMID: 30581198    Free PMC article.
Letrozole-associated controlled ovarian hyperstimulation in breast cancer patients versus conventional controlled ovarian hyperstimulation in infertile patients: assessment of oocyte quality related biomarkers.
Oranite Goldrat, Geraldine Van Den Steen, +6 authors, Isabelle Demeestere.
Reprod Biol Endocrinol, 2019 Jan 05; 17(1). PMID: 30606204    Free PMC article.
Event-free survival following early endometrial events in breast cancer patients treated with anti-hormonal therapy: A nationwide claims data study.
Yura Lee, Yu Rang Park, Hae Reong Kim, Jong Won Lee.
Medicine (Baltimore), 2019 Jan 12; 98(2). PMID: 30633178    Free PMC article.
Y-box binding protein YBX1 and its correlated genes as biomarkers for poor outcomes in patients with breast cancer.
Tomohiro Shibata, Eriko Tokunaga, +9 authors, Mayumi Ono.
Oncotarget, 2019 Jan 17; 9(98). PMID: 30647855    Free PMC article.
Association between tamoxifen use and acute myocardial infarction in women with breast cancer.
Shih-Wei Lai, Cheng-Li Lin, Kuan-Fu Liao.
Medicine (Baltimore), 2019 Jan 18; 98(3). PMID: 30653098    Free PMC article.
Differential Involvement of Autophagy and Apoptosis in Response to Chemoendocrine and Endocrine Therapy in Breast Cancer: JBCRG-07TR.
Takayuki Ueno, Norikazu Masuda, +5 authors, Masakazu Toi.
Int J Mol Sci, 2019 Mar 01; 20(4). PMID: 30813476    Free PMC article.
Decision Support for a Woman Considering Continuing Extended Endocrine Therapy for Breast Cancer: A Case Study.
Carrie M Liska, Dawn Stacey.
Can Oncol Nurs J, 2016 Oct 01; 26(4). PMID: 31148668    Free PMC article.

Carrie M Liska, Dawn Stacey.
Can Oncol Nurs J, 2016 Oct 01; 26(4). PMID: 31148685    Free PMC article.
Pharmacogenomics, CYP2D6, and Tamoxifen: A Survey of the Reasons Sustaining European Clinical Practice Paradigms.
Sara S Reis, Ana S Carvalho, Rúben Fernandes.
Medicina (Kaunas), 2019 Jul 10; 55(7). PMID: 31284530    Free PMC article.
CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer.
Elisabet Frick, Thorkell Gudjonsson, +4 authors, Stefan Sigurdsson.
Oncotarget, 2019 Aug 07; 10(45). PMID: 31384394    Free PMC article.
CRISPR-Cas9 Genome-Wide Knockout Screen Identifies Mechanism of Selective Activity of Dehydrofalcarinol in Mesenchymal Stem-like Triple-Negative Breast Cancer Cells.
Corena V Grant, Shengxin Cai, +5 authors, Susan L Mooberry.
J Nat Prod, 2020 Oct 07; 83(10). PMID: 33021790    Free PMC article.
Development of a Prognostic Tool to Guide the Decision to Extend Adjuvant Aromatase Inhibitors for up to Ten Years in Postmenopausal Early Breast Cancer Patients.
Camille Moreau-Bachelard, Loïc Campion, +6 authors, Jean-Sébastien Frénel.
Cancers (Basel), 2020 Dec 17; 12(12). PMID: 33322473    Free PMC article.
Current Status of Circulating Tumor Cells, Circulating Tumor DNA, and Exosomes in Breast Cancer Liquid Biopsies.
Marta Tellez-Gabriel, Erik Knutsen, Maria Perander.
Int J Mol Sci, 2020 Dec 17; 21(24). PMID: 33322643    Free PMC article.
Review.
Differential expression of the BCAT isoforms between breast cancer subtypes.
Mai Ahmed Shafei, Arwa Flemban, +5 authors, Myra E Conway.
Breast Cancer, 2020 Dec 29; 28(3). PMID: 33367952    Free PMC article.
Acquired mutations and transcriptional remodeling in long-term estrogen-deprived locoregional breast cancer recurrences.
Nolan Priedigkeit, Kai Ding, +9 authors, Adrian V Lee.
Breast Cancer Res, 2021 Jan 08; 23(1). PMID: 33407744    Free PMC article.
Study protocol for a randomised controlled feasibility trial of a virtual intervention (STRIDE) for symptom management, distress and adherence to adjuvant endocrine therapy after breast cancer.
Jamie M Jacobs, Chelsea S Rapoport, +5 authors, Joseph A Greer.
BMJ Open, 2021 Jan 06; 11(1). PMID: 33397667    Free PMC article.
Understanding ER+ Breast Cancer Dormancy Using Bioinspired Synthetic Matrices for Long-Term 3D Culture and Insights into Late Recurrence.
Elisa M Ovadia, Lina Pradhan, +8 authors, April M Kloxin.
Adv Biosyst, 2020 Jul 01; 4(9). PMID: 32603024    Free PMC article.
Therapy Algorithms for the Diagnosis and Treatment of Patients with Early and Advanced Breast Cancer.
Andreas Schneeweiss, Ingo Bauerfeind, +5 authors, Volkmar Müller.
Breast Care (Basel), 2021 Jan 16; 15(6). PMID: 33447235    Free PMC article.
Review.
The clinical usefulness of the CTS5 in the prediction of late distant recurrence in postmenopausal women with estrogen receptor-positive early breast cancer.
Wakako Tajiri, Hideki Ijichi, +8 authors, Eriko Tokunaga.
Breast Cancer, 2020 Jul 01; 28(1). PMID: 32601800    Free PMC article.
The role of capecitabine-based neoadjuvant and adjuvant chemotherapy in early-stage triple-negative breast cancer: a systematic review and meta-analysis.
Xingfa Huo, Jinming Li, +5 authors, Jiuda Zhao.
BMC Cancer, 2021 Jan 21; 21(1). PMID: 33468087    Free PMC article.
Body Composition Analysis of 10 Years versus 5 Years of Adjuvant Endocrine Therapy in Patients with Nonmetastatic Breast Cancer.
Ruyi Hu, Xinran Cheng, +5 authors, Zhaoshi Yu.
J Oncol, 2021 Jan 30; 2021. PMID: 33510788    Free PMC article.
Survivors of primary breast cancer 5 years after surgery: follow-up care, long-term problems, and treatment regrets. Results of the prospective BRENDA II-study.
Elena Leinert, Rolf Kreienberg, +8 authors, BRENDA study group.
Arch Gynecol Obstet, 2020 Jan 29; 301(3). PMID: 31989290
Hsa_circ_0025202 suppresses cell tumorigenesis and tamoxifen resistance via miR-197-3p/HIPK3 axis in breast cancer.
Hongjuan Li, Qing Li, Shan He.
World J Surg Oncol, 2021 Feb 05; 19(1). PMID: 33536026    Free PMC article.
Proactive visual and statistical analysis of genomic data in Epiviz.
Zhe Cui, Jayaram Kancherla, +2 authors, Héctor Corrada Bravo.
Bioinformatics, 2019 Nov 30; 36(7). PMID: 31782758    Free PMC article.
FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer: rationale for a triple blockade of ER, CDK4/6, and FGFR1.
Silvana Mouron, Luis Manso, +6 authors, Maria J Bueno.
Breast Cancer Res, 2021 Feb 14; 23(1). PMID: 33579347    Free PMC article.
Cancer progression and the invisible phase of metastatic colonization.
Christoph A Klein.
Nat Rev Cancer, 2020 Oct 08; 20(11). PMID: 33024261
Review.
The Effect of Subsequent Pregnancy on Prognosis in Young Breast Cancer Patients (≤35 Years Old) According to Hormone Receptor Status.
Yang Li, Yuhan Zhang, +3 authors, Hong Liu.
Cancer Manag Res, 2021 Feb 25; 13. PMID: 33623430    Free PMC article.
Early Discontinuation of Endocrine Therapy and Recurrence of Breast Cancer among Premenopausal Women.
Lindsay J Collin, Deirdre P Cronin-Fenton, +10 authors, Timothy L Lash.
Clin Cancer Res, 2020 Dec 19; 27(5). PMID: 33334905    Free PMC article.
Estrogen receptor alpha in the brain mediates tamoxifen-induced changes in physiology in mice.
Zhi Zhang, Jae Whan Park, +6 authors, Stephanie M Correa.
Elife, 2021 Mar 02; 10. PMID: 33647234    Free PMC article.
Therapeutic Advances in Oncology.
Jinsha Liu, Priyanka Pandya, Sepideh Afshar.
Int J Mol Sci, 2021 Mar 07; 22(4). PMID: 33670524    Free PMC article.
Review.
Molecular Biomarkers for Contemporary Therapies in Hormone Receptor-Positive Breast Cancer.
Allegra Freelander, Lauren J Brown, +4 authors, Elgene Lim.
Genes (Basel), 2021 Mar 07; 12(2). PMID: 33671468    Free PMC article.
Review.
Case Report: Long-Term Response to Pembrolizumab Combined With Endocrine Therapy in Metastatic Breast Cancer Patients With Hormone Receptor Expression.
Dingyong Wu, Shu Tang, +6 authors, Zhengtang Chen.
Front Immunol, 2021 Mar 12; 12. PMID: 33692787    Free PMC article.
Clinical validity of clinical treatment score 5 (CTS5) for estimating risk of late recurrence in unselected, non-trial patients with early oestrogen receptor-positive breast cancer.
Juliet Richman, Alistair Ring, Mitch Dowsett, Ivana Sestak.
Breast Cancer Res Treat, 2020 Nov 23; 186(1). PMID: 33222093    Free PMC article.
The Role of Chemotherapy in Patients With HER2-Negative Isolated Locoregional Recurrence of Breast Cancer: A Multicenter Retrospective Cohort Study.
Kyoungmin Lee, Sung Hoon Sim, +9 authors, In Hae Park.
Front Oncol, 2021 Mar 23; 11. PMID: 33747970    Free PMC article.
Positive estrogen receptor status is a poor prognostic factor in node-negative breast cancer: An observational study in Asian patients.
Eun Jung Jung, Ju-Yeon Kim, +9 authors, Soon-Chang Hong.
Medicine (Baltimore), 2021 Mar 18; 100(11). PMID: 33725973    Free PMC article.
What is behind the fear of cancer during menopausal hormone therapy in China?
Yanfang Wang, Wei Wang, +9 authors, Aijun Sun.
Arch Gynecol Obstet, 2021 Apr 05;. PMID: 33813609
Generating a Precision Endoxifen Prediction Algorithm to Advance Personalized Tamoxifen Treatment in Patients with Breast Cancer.
Thomas Helland, Sarah Alsomairy, +3 authors, Daniel Louis Hertz.
J Pers Med, 2021 Apr 04; 11(3). PMID: 33805613    Free PMC article.
Review.
The multigene classifiers 95GC/42GC/155GC for precision medicine in ER-positive HER2-negative early breast cancer.
Yasuto Naoi, Ryo Tsunashima, Kenzo Shimazu, Shinzaburo Noguchi.
Cancer Sci, 2021 Feb 06; 112(4). PMID: 33544932    Free PMC article.
Review.
Update on systemic treatment for newly diagnosed inflammatory breast cancer.
Sudpreeda Chainitikun, Sadia Saleem, +2 authors, Naoto T Ueno.
J Adv Res, 2021 Apr 13; 29. PMID: 33842000    Free PMC article.
Low Z-4OHtam concentrations are associated with adverse clinical outcome among early stage premenopausal breast cancer patients treated with adjuvant tamoxifen.
Thomas Helland, Bjørn Naume, +15 authors, Håvard Søiland.
Mol Oncol, 2020 Dec 01; 15(4). PMID: 33252186    Free PMC article.
Development of a self-management intervention to improve tamoxifen adherence in breast cancer survivors using an Intervention Mapping framework.
Zoe Moon, Rona Moss-Morris, Myra S Hunter, Lyndsay D Hughes.
Support Care Cancer, 2020 Oct 30; 29(6). PMID: 33118106    Free PMC article.
Emerging strategies for treating metastasis.
Mark Esposito, Shridar Ganesan, Yibin Kang.
Nat Cancer, 2021 Apr 27; 2(3). PMID: 33899000    Free PMC article.
Breast Cancer Clinical Trials: The Landscape at the Uganda Cancer Institute and Lessons Learned.
Manoj P Menon, Nixon Niyonzima, Julie Gralow, Jackson Orem.
JCO Glob Oncol, 2021 Jan 16; 7. PMID: 33449804    Free PMC article.
A follow-up study of a randomized controlled study evaluating safety and efficacy of leuprorelin acetate every-3-month depot for 2 versus 3 or more years with tamoxifen for 5 years as adjuvant treatment in premenopausal patients with endocrine-responsive breast cancer.
Junichi Kurebayashi, Eiichi Shiba, +6 authors, Yasuo Ohashi.
Breast Cancer, 2021 Feb 28; 28(3). PMID: 33638810    Free PMC article.
Luminal Breast Cancer: Risk of Recurrence and Tumor-Associated Immune Suppression.
Benedetta Pellegrino, Zuzana Hlavata, +5 authors, Cinzia Solinas.
Mol Diagn Ther, 2021 May 12; 25(4). PMID: 33974235    Free PMC article.
Review.
Levonorgestrel intrauterine system for endometrial protection in women with breast cancer on adjuvant tamoxifen.
Sally Ad Romero, Katie Young, Martha Hickey, H Irene Su.
Cochrane Database Syst Rev, 2020 Dec 22; 12. PMID: 33348436    Free PMC article.
Systematic Review.
Breast Cancer Therapeutics and Biomarkers: Past, Present, and Future Approaches.
Jason Schick, Raquel P Ritchie, Carolina Restini.
Breast Cancer (Auckl), 2021 May 18; 15. PMID: 33994789    Free PMC article.
Review.
Metabolic comorbidities and the association with risks of recurrent metastatic disease in breast cancer survivors.
Sumadi Lukman Anwar, Roby Cahyono, +5 authors, Teguh Aryandono.
BMC Cancer, 2021 May 24; 21(1). PMID: 34022845    Free PMC article.
Current Landscape of Targeted Therapy in Hormone Receptor-Positive and HER2-Negative Breast Cancer.
Samitha Andrahennadi, Amer Sami, +2 authors, Shahid Ahmed.
Curr Oncol, 2021 Jun 03; 28(3). PMID: 34064867    Free PMC article.
Review.
Patterns of Recurrence after Neoadjuvant Therapy in Early Breast Cancer, according to the Residual Cancer Burden Index and Reductions in Neoadjuvant Treatment Intensity.
Christoph Suppan, Florian Posch, +11 authors, Marija Balic.
Cancers (Basel), 2021 Jun 03; 13(10). PMID: 34065332    Free PMC article.
Inhibition of Antiestrogen-Promoted Pro-Survival Autophagy and Tamoxifen Resistance in Breast Cancer through Vitamin D Receptor.
Ye Li, Katherine L Cook, +4 authors, Leena Hilakivi-Clarke.
Nutrients, 2021 Jun 03; 13(5). PMID: 34069442    Free PMC article.
Risk of primary lung cancer after adjuvant radiotherapy in breast cancer-a large population-based study.
Anna-Karin Wennstig, Charlotta Wadsten, +6 authors, Malin Sund.
NPJ Breast Cancer, 2021 Jun 03; 7(1). PMID: 34075042    Free PMC article.
Volumetric Absorptive Microsampling as a New Biosampling Tool for Monitoring of Tamoxifen, Endoxifen, 4-OH Tamoxifen and N-Desmethyltamoxifen in Breast Cancer Patients.
Baitha Palanggatan Maggadani, Harmita, +2 authors, Yahdiana Harahap.
Drug Des Devel Ther, 2021 Jun 12; 15. PMID: 34113081    Free PMC article.
Risk of Endometrial Cancer and Frequencies of Invasive Endometrial Procedures in Young Breast Cancer Survivors Treated With Tamoxifen: A Nationwide Study.
Soojeong Choi, Young Jae Lee, +8 authors, Il Yong Chung.
Front Oncol, 2021 Jun 22; 11. PMID: 34150613    Free PMC article.
Randomized Phase II Study of 3 Months or 2 Years of Adjuvant Afatinib in Patients With Surgically Resected Stage I-III EGFR-Mutant Non-Small-Cell Lung Cancer.
Joel W Neal, Daniel B Costa, +11 authors, Jamie E Chaft.
JCO Precis Oncol, 2021 Jun 22; 5. PMID: 34151132    Free PMC article.
Overcoming oncogene addiction in breast and prostate cancers: a comparative mechanistic overview.
Eliot B Blatt, Noa Kopplin, +3 authors, Ganesh V Raj.
Endocr Relat Cancer, 2020 Dec 03; 28(2). PMID: 33263560    Free PMC article.
Review.
Analysis of tamoxifen and its metabolites in dried blood spot and volumetric absorptive microsampling: comparison and clinical application.
Baitha Palanggatan Maggadani, Yahdiana Harahap, +2 authors, Christoffel William Putra Untu.
Heliyon, 2021 Jun 29; 7(6). PMID: 34179536    Free PMC article.
Decision aids linked to evidence summaries and clinical practice guidelines: results from user-testing in clinical encounters.
Anja Fog Heen, Per Olav Vandvik, +5 authors, Thomas Agoritsas.
BMC Med Inform Decis Mak, 2021 Jul 01; 21(1). PMID: 34187484    Free PMC article.
Extending Adjuvant Endocrine Therapy for 10 Years: A Mixed-Methods Analysis of Women's Decision Making in an Online Breast Cancer Forum.
Yolanda Eraso, Denes Stefler, +2 authors, Sidona Assefa.
Healthcare (Basel), 2021 Jul 03; 9(6). PMID: 34200326    Free PMC article.
Validation of the Clinical Treatment Score Post-Five Years in Breast Cancer Patients for Predicting Late Distant Recurrence: A Single-Center Investigation in Korea.
Jun-Hee Lee, Se Kyung Lee, +5 authors, Jai Min Ryu.
Front Oncol, 2021 Jul 10; 11. PMID: 34239805    Free PMC article.
Does the Time of Day at Which Endocrine Therapy Is Taken Affect Breast Cancer Patient Outcomes?
Ana-Alicia Beltran-Bless, Lisa Vandermeer, +4 authors, Mark Clemons.
Curr Oncol, 2021 Jul 22; 28(4). PMID: 34287262    Free PMC article.
Molecular Mechanism and Prevention Strategy of Chemotherapy- and Radiotherapy-Induced Ovarian Damage.
Seongmin Kim, Sung-Woo Kim, +4 authors, Tak Kim.
Int J Mol Sci, 2021 Jul 25; 22(14). PMID: 34299104    Free PMC article.
Review.