Review
. 2013 Jul; 39(1):1-10.
doi: 10.1016/j.immuni.2013.07.012.

Oncology meets immunology: the cancer-immunity cycle

Daniel S Chen 1 Ira Mellman  
Affiliations
  • PMID: 23890059
  •     1811 citations

Abstract

The genetic and cellular alterations that define cancer provide the immune system with the means to generate T cell responses that recognize and eradicate cancer cells. However, elimination of cancer by T cells is only one step in the Cancer-Immunity Cycle, which manages the delicate balance between the recognition of nonself and the prevention of autoimmunity. Identification of cancer cell T cell inhibitory signals, including PD-L1, has prompted the development of a new class of cancer immunotherapy that specifically hinders immune effector inhibition, reinvigorating and potentially expanding preexisting anticancer immune responses. The presence of suppressive factors in the tumor microenvironment may explain the limited activity observed with previous immune-based therapies and why these therapies may be more effective in combination with agents that target other steps of the cycle. Emerging clinical data suggest that cancer immunotherapy is likely to become a key part of the clinical management of cancer.

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Highly Cited. Review.
Immunotherapy and Novel Combinations in Oncology: Current Landscape, Challenges, and Opportunities.
K M Morrissey, T M Yuraszeck, +2 authors, S Kasichayanula.
Clin Transl Sci, 2016 Mar 01; 9(2). PMID: 26924066    Free PMC article.
Highly Cited. Review.
RRx-001-Induced Tumor Necrosis and Immune Cell Infiltration in an EGFR Mutation-Positive NSCLC with Resistance to EGFR Tyrosine Kinase Inhibitors: A Case Report.
Christina Brzezniak, Bruno A Schmitz, +5 authors, Corey A Carter.
Case Rep Oncol, 2016 Mar 05; 9(1). PMID: 26933418    Free PMC article.
Melanoma cell lysosome secretory burst neutralizes the CTL-mediated cytotoxicity at the lytic synapse.
Roxana Khazen, Sabina Müller, +3 authors, Salvatore Valitutti.
Nat Commun, 2016 Mar 05; 7. PMID: 26940455    Free PMC article.
Altered expression of major immune regulatory molecules in peripheral blood immune cells associated with breast cancer.
Kosuke Kawaguchi, Eiji Suzuki, +3 authors, Masakazu Toi.
Breast Cancer, 2016 Mar 05; 24(1). PMID: 26942414    Free PMC article.
Long story short: p53 mediates innate immunity.
Jessica Miciak, Fred Bunz.
Biochim Biophys Acta, 2016 Mar 10; 1865(2). PMID: 26951863    Free PMC article.
Review.
Development of immuno-oncology drugs - from CTLA4 to PD1 to the next generations.
Axel Hoos.
Nat Rev Drug Discov, 2016 Mar 12; 15(4). PMID: 26965203
Highly Cited.
Myelodysplastic Syndrome Revealed by Systems Immunology in a Melanoma Patient Undergoing Anti-PD-1 Therapy.
Allison R Greenplate, Douglas B Johnson, +5 authors, Jonathan M Irish.
Cancer Immunol Res, 2016 Mar 12; 4(6). PMID: 26966176    Free PMC article.
The Basis of Oncoimmunology.
A Karolina Palucka, Lisa M Coussens.
Cell, 2016 Mar 12; 164(6). PMID: 26967289    Free PMC article.
Highly Cited. Review.
Dendritic cell-derived exosomes for cancer therapy.
Jonathan M Pitt, Fabrice André, +4 authors, Laurence Zitvogel.
J Clin Invest, 2016 Apr 02; 126(4). PMID: 27035813    Free PMC article.
Highly Cited. Review.
Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.
Hélène Salmon, Juliana Idoyaga, +19 authors, Miriam Merad.
Immunity, 2016 Apr 21; 44(4). PMID: 27096321    Free PMC article.
Highly Cited.
Potentiation of immunomodulatory antibody therapy with oncolytic viruses for treatment of cancer.
Dmitriy Zamarin, Jedd D Wolchok.
Mol Ther Oncolytics, 2014 Jan 01; 1. PMID: 27119094    Free PMC article.
Review.
Role of the tumor microenvironment in mature B-cell lymphoid malignancies.
Nathan H Fowler, Chan Yoon Cheah, +13 authors, Kieron Dunleavy.
Haematologica, 2016 May 02; 101(5). PMID: 27132279    Free PMC article.
Review.
Nivolumab, anti-programmed death-1 (PD-1) monoclonal antibody immunotherapy: Role in advanced cancers.
Arun Rajan, Chul Kim, +2 authors, James L Gulley.
Hum Vaccin Immunother, 2016 May 03; 12(9). PMID: 27135835    Free PMC article.
Review.
Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC.
Benjamin Besse, Mélinda Charrier, +25 authors, Nathalie Chaput.
Oncoimmunology, 2016 May 04; 5(4). PMID: 27141373    Free PMC article.
Highly Cited.
Perspectives on sipuleucel-T: Its role in the prostate cancer treatment paradigm.
James L Gulley, Peter Mulders, +4 authors, Thomas Powles.
Oncoimmunology, 2016 May 04; 5(4). PMID: 27141392    Free PMC article.
Review.
Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity.
Yuan Hong, Indumathi Manoharan, +10 authors, Santhakumar Manicassamy.
Oncoimmunology, 2016 May 04; 5(4). PMID: 27141399    Free PMC article.
Cancer immunotherapy: the beginning of the end of cancer?
Sofia Farkona, Eleftherios P Diamandis, Ivan M Blasutig.
BMC Med, 2016 May 07; 14. PMID: 27151159    Free PMC article.
Highly Cited. Review.
Systems immune monitoring in cancer therapy.
Allison R Greenplate, Douglas B Johnson, P Brent Ferrell, Jonathan M Irish.
Eur J Cancer, 2016 May 08; 61. PMID: 27155446    Free PMC article.
Review.
[Systemic treatment of inoperable metastasized malignant melanoma].
R Gutzmer, R Rauschenberg, F Meier.
Hautarzt, 2016 May 12; 67(7). PMID: 27164828
Review.
Burden of Nonsynonymous Mutations among TCGA Cancers and Candidate Immune Checkpoint Inhibitor Responses.
Leandro M Colli, Mitchell J Machiela, +3 authors, Stephen J Chanock.
Cancer Res, 2016 May 20; 76(13). PMID: 27197178    Free PMC article.
Highly Cited.
Immune-related Adverse Events of Dendritic Cell Vaccination Correlate With Immunologic and Clinical Outcome in Stage III and IV Melanoma Patients.
Steve Boudewijns, Harm Westdorp, +8 authors, Kalijn F Bol.
J Immunother, 2016 May 27; 39(6). PMID: 27227325    Free PMC article.
Targeting the Tumor Environment in Squamous Cell Carcinoma of the Head and Neck.
Sandra Schmitz, Jean-Pascal Machiels.
Curr Treat Options Oncol, 2016 Jun 06; 17(7). PMID: 27262711
Review.
Execution of RIPK3-regulated necrosis.
Zhenyu Cai, Zheng-Gang Liu.
Mol Cell Oncol, 2014 Apr 01; 1(2). PMID: 27308332    Free PMC article.
Review.
Intratumoral expression of programmed death ligand 1 (PD-L1) in patients with clear cell renal cell carcinoma (ccRCC).
M Abbas, S Steffens, +7 authors, P Ivanyi.
Med Oncol, 2016 Jun 19; 33(7). PMID: 27317388
Dendritic cell vaccination in melanoma patients: From promising results to future perspectives.
Steve Boudewijns, Martine Bloemendal, +2 authors, Gerty Schreibelt.
Hum Vaccin Immunother, 2016 Jun 21; 12(10). PMID: 27322496    Free PMC article.
Immune checkpoint blockade therapy for bladder cancer treatment.
Jayoung Kim.
Investig Clin Urol, 2016 Jun 22; 57 Suppl 1. PMID: 27326412    Free PMC article.
Review.
Phase I dose-finding study of monotherapy with atezolizumab, an engineered immunoglobulin monoclonal antibody targeting PD-L1, in Japanese patients with advanced solid tumors.
Hidenori Mizugaki, Noboru Yamamoto, +5 authors, Toshiaki Takahashi.
Invest New Drugs, 2016 Jul 02; 34(5). PMID: 27363843    Free PMC article.
Systematic review of the use of granulocyte-macrophage colony-stimulating factor in patients with advanced melanoma.
Christoph Hoeller, Olivier Michielin, +2 authors, Christian U Blank.
Cancer Immunol Immunother, 2016 Jul 04; 65(9). PMID: 27372293    Free PMC article.
Systematic Review.
Inhibiting Immune Checkpoints for the Treatment of Bladder Cancer.
S Bidnur, R Savdie, P C Black.
Bladder Cancer, 2016 Jul 05; 2(1). PMID: 27376121    Free PMC article.
Review.
Computational genomics tools for dissecting tumour-immune cell interactions.
Hubert Hackl, Pornpimol Charoentong, Francesca Finotello, Zlatko Trajanoski.
Nat Rev Genet, 2016 Jul 05; 17(8). PMID: 27376489
Highly Cited. Review.
A transient increase and subsequent sharp decrease of chemo-refractory liver-metastasized uterine cervical small cell carcinoma to autologous formalin-fixed tumor vaccine plus anti-PD-1 antibody.
Tatsu Miyoshi, Tatsuji Kataoka, +4 authors, Tadao Ohno.
Clin Case Rep, 2016 Jul 08; 4(7). PMID: 27386130    Free PMC article.
Clinician Perspectives on Current Issues in Lung Cancer Drug Development.
Saiama N Waqar, Philip D Bonomi, +17 authors, Gideon M Blumenthal.
J Thorac Oncol, 2016 Jul 13; 11(9). PMID: 27401214    Free PMC article.
Review.
Recent advances and future of immunotherapy for glioblastoma.
Neha Kamran, Alexandra Calinescu, +7 authors, Maria G Castro.
Expert Opin Biol Ther, 2016 Jul 14; 16(10). PMID: 27411023    Free PMC article.
Review.
High expression levels of egfl7 correlate with low endothelial cell activation in peritumoral vessels of human breast cancer.
Diane Pannier, Géraldine Philippin-Lauridant, +7 authors, Fabrice Soncin.
Oncol Lett, 2016 Jul 23; 12(2). PMID: 27446447    Free PMC article.
Challenges of Using High-Dose Fractionation Radiotherapy in Combination Therapy.
Ying-Chieh Yang, Chi-Shiun Chiang.
Front Oncol, 2016 Jul 23; 6. PMID: 27446811    Free PMC article.
Review.
Personalized Medicine Approaches in Prostate Cancer Employing Patient Derived 3D Organoids and Humanized Mice.
Monica Bartucci, Anna C Ferrari, +3 authors, Hatem E Sabaawy.
Front Cell Dev Biol, 2016 Jul 23; 4. PMID: 27446916    Free PMC article.
Personalized cancer vaccines: Targeting the cancer mutanome.
Xiuli Zhang, Piyush K Sharma, S Peter Goedegebuure, William E Gillanders.
Vaccine, 2016 Jul 28; 35(7). PMID: 27449681    Free PMC article.
Review.
PD-L1 Detection in Tumors Using [(64)Cu]Atezolizumab with PET.
Wojciech G Lesniak, Samit Chatterjee, +4 authors, Sridhar Nimmagadda.
Bioconjug Chem, 2016 Jul 28; 27(9). PMID: 27458027    Free PMC article.
Nonmuscle invasive bladder cancer: a primer on immunotherapy.
Mahir Maruf, Sam J Brancato, Piyush K Agarwal.
Cancer Biol Med, 2016 Jul 28; 13(2). PMID: 27458527    Free PMC article.
Therapeutic cancer vaccines and combination immunotherapies involving vaccination.
Trang Nguyen, Julie Urban, Pawel Kalinski.
Immunotargets Ther, 2014 Jan 01; 3. PMID: 27471705    Free PMC article.
Review.
CXCL9 and CXCL10 predict survival and are regulated by cyclooxygenase inhibition in advanced serous ovarian cancer.
Holger Bronger, Judith Singer, +8 authors, Stefanie Avril.
Br J Cancer, 2016 Aug 05; 115(5). PMID: 27490802    Free PMC article.
Highly Cited.
Clinical, pharmacodynamic and pharmacokinetic results of a prospective phase II study on oral metronomic vinorelbine and dexamethasone in castration-resistant prostate cancer patients.
Teresa Di Desidero, Lisa Derosa, +14 authors, Guido Bocci.
Invest New Drugs, 2016 Aug 26; 34(6). PMID: 27557783
Towards tumor immunodiagnostics.
Helen Kourea, Vassiliki Kotoula.
Ann Transl Med, 2016 Aug 27; 4(14). PMID: 27563650    Free PMC article.
Review.
Functional exhaustion of CD4+ T cells induced by co-stimulatory signals from myeloid leukaemia cells.
Didem Ozkazanc, Digdem Yoyen-Ermis, +2 authors, Gunes Esendagli.
Immunology, 2016 Nov 05; 149(4). PMID: 27565576    Free PMC article.
Gastric cancer: current and evolving treatment landscape.
Weijing Sun, Li Yan.
Chin J Cancer, 2016 Sep 02; 35(1). PMID: 27581465    Free PMC article.
Review.
Concepts and targets in triple-negative breast cancer: recent results and clinical implications.
Poornima Saha, Rita Nanda.
Ther Adv Med Oncol, 2016 Sep 02; 8(5). PMID: 27583027    Free PMC article.
Review.
Corrigendum: Personalized Medicine Approaches in Prostate Cancer Employing Patient Derived 3D Organoids and Humanized Mice.
Monica Bartucci, Anna C Ferrari, +3 authors, Hatem E Sabaawy.
Front Cell Dev Biol, 2016 Sep 02; 4. PMID: 27583246    Free PMC article.
Simultaneous monitoring of oxidation, deamidation, isomerization, and glycosylation of monoclonal antibodies by liquid chromatography-mass spectrometry method with ultrafast tryptic digestion.
Yi Wang, Xiaojuan Li, +4 authors, Xiaoyu Yang.
MAbs, 2016 Oct 30; 8(8). PMID: 27598507    Free PMC article.
From the era of ineffective tumor vaccines to a future with effective immunotherapy.
Wolter Igor Quincy de Waard, Michel Maria van den Heuvel.
J Thorac Dis, 2016 Sep 14; 8(8). PMID: 27621843    Free PMC article.
Adjuvant dendritic cell vaccination induces tumor-specific immune responses in the majority of stage III melanoma patients.
Steve Boudewijns, Kalijn F Bol, +19 authors, I Jolanda M de Vries.
Oncoimmunology, 2016 Sep 14; 5(7). PMID: 27622047    Free PMC article.
No evidence for TSLP pathway activity in human breast cancer.
Cristina Ghirelli, Benjamin Sadacca, +9 authors, Vassili Soumelis.
Oncoimmunology, 2016 Sep 14; 5(8). PMID: 27622057    Free PMC article.
T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells.
Ilaria Marigo, Serena Zilio, +18 authors, Vincenzo Bronte.
Cancer Cell, 2016 Sep 14; 30(3). PMID: 27622331    Free PMC article.
Highly Cited.
Current clinical trials testing the combination of immunotherapy with radiotherapy.
Josephine Kang, Sandra Demaria, Silvia Formenti.
J Immunother Cancer, 2016 Sep 24; 4. PMID: 27660705    Free PMC article.
Highly Cited.
Optogenetic Immunomodulation: Shedding Light on Antitumor Immunity.
Peng Tan, Lian He, Gang Han, Yubin Zhou.
Trends Biotechnol, 2016 Oct 04; 35(3). PMID: 27692897    Free PMC article.
Review.
Genomic Approaches to Understanding Response and Resistance to Immunotherapy.
David A Braun, Kelly P Burke, Eliezer M Van Allen.
Clin Cancer Res, 2016 Oct 05; 22(23). PMID: 27698000    Free PMC article.
Review.
Mathematical Models for Immunology: Current State of the Art and Future Research Directions.
Raluca Eftimie, Joseph J Gillard, Doreen A Cantrell.
Bull Math Biol, 2016 Oct 21; 78(10). PMID: 27714570    Free PMC article.
Review.
Rekindling cancer vaccines.
Malorye Allison Branca.
Nat Biotechnol, 2016 Oct 12; 34(10). PMID: 27727216
Soluble fibrinogen like protein 2 (sFGL2), the novel effector molecule for immunoregulation.
Xin-Guang Liu, Yu Liu, Feng Chen.
Oncotarget, 2016 Oct 13; 8(2). PMID: 27732962    Free PMC article.
Review.
Dendritic Cells and Cancer Immunity.
Alycia Gardner, Brian Ruffell.
Trends Immunol, 2016 Oct 30; 37(12). PMID: 27793569    Free PMC article.
Highly Cited. Review.
Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy.
Ju Yeon Lee, Hyun Tae Lee, +11 authors, Yong-Seok Heo.
Nat Commun, 2016 Nov 01; 7. PMID: 27796306    Free PMC article.
Highly Cited.
Recent advances in understanding antitumor immunity.
Rodrigo Ramella Munhoz, Michael Andrew Postow.
F1000Res, 2016 Nov 03; 5. PMID: 27803807    Free PMC article.
Review.
Eph Receptor Tyrosine Kinases in Tumor Immunity.
Eileen Shiuan, Jin Chen.
Cancer Res, 2016 Nov 05; 76(22). PMID: 27811149    Free PMC article.
Review.
Elevated serum granulocyte-macrophage colony-stimulating factor levels during radiotherapy predict favorable outcomes in lung and esophageal cancer.
Guodong Deng, Pingping Hu, +11 authors, Jiandong Zhang.
Oncotarget, 2016 Nov 12; 7(51). PMID: 27835886    Free PMC article.
Immune checkpoint blockade in small cell lung cancer: is there a light at the end of the tunnel?
Luca Paglialunga, Zena Salih, Biagio Ricciuti, Raffaele Califano.
ESMO Open, 2016 Nov 16; 1(4). PMID: 27843619    Free PMC article.
Review.
Combination Approaches with Immune-Checkpoint Blockade in Cancer Therapy.
Maarten Swart, Inge Verbrugge, Joost B Beltman.
Front Oncol, 2016 Nov 17; 6. PMID: 27847783    Free PMC article.
Highly Cited. Review.
The Impact of Chemotherapy, Radiation and Epigenetic Modifiers in Cancer Cell Expression of Immune Inhibitory and Stimulatory Molecules and Anti-Tumor Efficacy.
Jessica Ann Chacon, Keith Schutsky, Daniel J Powell.
Vaccines (Basel), 2016 Nov 18; 4(4). PMID: 27854240    Free PMC article.
Review.
Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures.
Yasin Şenbabaoğlu, Ron S Gejman, +26 authors, A Ari Hakimi.
Genome Biol, 2016 Nov 20; 17(1). PMID: 27855702    Free PMC article.
Highly Cited.
Endoplasmic reticulum proteostasis: a key checkpoint in cancer.
Scott A Oakes.
Am J Physiol Cell Physiol, 2016 Nov 20; 312(2). PMID: 27856431    Free PMC article.
Review.
Programmed Death-Ligand 1 Expression and Response to the Anti-Programmed Death 1 Antibody Pembrolizumab in Melanoma.
Adil I Daud, Jedd D Wolchok, +21 authors, Omid Hamid.
J Clin Oncol, 2016 Nov 20; 34(34). PMID: 27863197    Free PMC article.
Highly Cited.
Immune checkpoint inhibition in patients with brain metastases.
Tanner Johanns, Saiama N Waqar, Daniel Morgensztern.
Ann Transl Med, 2016 Nov 22; 4(Suppl 1). PMID: 27867977    Free PMC article.
Potential applications of nanoparticles in cancer immunotherapy.
Yimei Jia, Abdelwahab Omri, Lakshmi Krishnan, Michael J McCluskie.
Hum Vaccin Immunother, 2016 Nov 22; 13(1). PMID: 27870598    Free PMC article.
Review.
The role of immune checkpoint inhibition in the treatment of ovarian cancer.
Stéphanie L Gaillard, Angeles A Secord, Bradley Monk.
Gynecol Oncol Res Pract, 2016 Dec 03; 3. PMID: 27904752    Free PMC article.
Review.
Predictive biomarkers for checkpoint inhibitor-based immunotherapy.
Geoffrey T Gibney, Louis M Weiner, Michael B Atkins.
Lancet Oncol, 2016 Dec 08; 17(12). PMID: 27924752    Free PMC article.
Highly Cited. Review.
Temporally Programmed CD8α+ DC Activation Enhances Combination Cancer Immunotherapy.
Alice Tzeng, Monique J Kauke, +9 authors, K Dane Wittrup.
Cell Rep, 2016 Dec 08; 17(10). PMID: 27926855    Free PMC article.
Biomimetic biodegradable artificial antigen presenting cells synergize with PD-1 blockade to treat melanoma.
A K Kosmides, R A Meyer, +4 authors, J P Schneck.
Biomaterials, 2016 Dec 13; 118. PMID: 27940380    Free PMC article.
Identifying and Creating the Next Generation of Community-Based Cancer Prevention Studies: Summary of a National Cancer Institute Think Tank.
Worta McCaskill-Stevens, Deborah C Pearson, +2 authors, Scott M Lippman.
Cancer Prev Res (Phila), 2016 Dec 15; 10(2). PMID: 27965286    Free PMC article.
Review.
Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial.
Achim Rittmeyer, Fabrice Barlesi, +23 authors, OAK Study Group.
Lancet, 2016 Dec 17; 389(10066). PMID: 27979383    Free PMC article.
Highly Cited.
Distinct immunological activation profiles of dSLIM® and ProMune® depend on their different structural context.
Kerstin Kapp, Jacqueline Schneider, +5 authors, Christiane Kleuss.
Immun Inflamm Dis, 2016 Dec 17; 4(4). PMID: 27980779    Free PMC article.
PD-L1 Expression and Combined Status of PD-L1/PD-1-Positive Tumor Infiltrating Mononuclear Cell Density Predict Prognosis in Glioblastoma Patients.
Jiheun Han, Yongkil Hong, Youn Soo Lee.
J Pathol Transl Med, 2016 Dec 19; 51(1). PMID: 27989100    Free PMC article.
Immune Checkpoint Blockade in Hepatocellular Carcinoma: 2017 Update.
M Kudo.
Liver Cancer, 2016 Dec 21; 6(1). PMID: 27995082    Free PMC article.
Commentary on Pharmacometrics for Immunotherapy.
M J Garrido, P Berraondo, I F Trocóniz.
CPT Pharmacometrics Syst Pharmacol, 2016 Dec 21; 6(1). PMID: 27997736    Free PMC article.
Interlesional diversity of T cell receptors in melanoma with immune checkpoints enriched in tissue-resident memory T cells.
Chandra Sekhar Boddupalli, Noffar Bar, +14 authors, Kavita M Dhodapkar.
JCI Insight, 2016 Dec 27; 1(21). PMID: 28018970    Free PMC article.
Soluble programmed death-ligand 1 as a prognostic biomarker for overall survival in patients with diffuse large B-cell lymphoma: a replication study and combined analysis of 508 patients.
D Rossille, I Azzaoui, +15 authors, T Fest.
Leukemia, 2016 Dec 31; 31(4). PMID: 28035137    Free PMC article.
nab-Paclitaxel as a potential partner with checkpoint inhibitors in solid tumors.
Hatem H Soliman.
Onco Targets Ther, 2017 Jan 06; 10. PMID: 28053544    Free PMC article.
Review.
Lysozyme association with circulating RNA, extracellular vesicles, and chronic stress.
Sarah K Abey, Yuana Yuana, +10 authors, Wendy A Henderson.
BBA Clin, 2017 Jan 06; 7. PMID: 28053879    Free PMC article.
Immunotherapy: incorporation in the evolving paradigm of renal cancer management and future prospects.
Kenneth G Liu, Sorab Gupta, Sanjay Goel.
Oncotarget, 2017 Jan 07; 8(10). PMID: 28061473    Free PMC article.
Review.
Is immunotherapy here to stay in multiple myeloma?
Paula Rodríguez-Otero, Bruno Paiva, +2 authors, Jesús F San Miguel.
Haematologica, 2017 Jan 14; 102(3). PMID: 28082344    Free PMC article.
Review.
Inferring the Impact of Regulatory Mechanisms that Underpin CD8+ T Cell Control of B16 Tumor Growth In vivo Using Mechanistic Models and Simulation.
David J Klinke, Qing Wang.
Front Pharmacol, 2017 Jan 20; 7. PMID: 28101055    Free PMC article.
Elements of cancer immunity and the cancer-immune set point.
Daniel S Chen, Ira Mellman.
Nature, 2017 Jan 20; 541(7637). PMID: 28102259
Highly Cited. Review.
Systemic Immunity Is Required for Effective Cancer Immunotherapy.
Matthew H Spitzer, Yaron Carmi, +10 authors, Edgar G Engleman.
Cell, 2017 Jan 24; 168(3). PMID: 28111070    Free PMC article.
Highly Cited.
The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches.
Pankita H Pandya, Mary E Murray, Karen E Pollok, Jamie L Renbarger.
J Immunol Res, 2017 Jan 25; 2016. PMID: 28116316    Free PMC article.
Review.
PD-1, PD-L1 (B7-H1) and Tumor-Site Immune Modulation Therapy: The Historical Perspective.
Jun Wang, Ruirong Yuan, +3 authors, Zihai Li.
J Hematol Oncol, 2017 Jan 27; 10(1). PMID: 28122590    Free PMC article.
Highly Cited. Review.
Distinct transcriptional changes in non-small cell lung cancer patients associated with multi-antigenic RNActive® CV9201 immunotherapy.
Henoch S Hong, Sven D Koch, +9 authors, James M Billingsley.
Oncoimmunology, 2017 Jan 27; 5(12). PMID: 28123889    Free PMC article.
BTLA identifies dysfunctional PD-1-expressing CD4+ T cells in human hepatocellular carcinoma.
Qiyi Zhao, Zhan-Lian Huang, +2 authors, Dong-Ming Kuang.
Oncoimmunology, 2017 Jan 27; 5(12). PMID: 28123898    Free PMC article.
Antibody-dependent cell cytotoxicity: immunotherapy strategies enhancing effector NK cells.
Maria Carmen Ochoa, Luna Minute, +5 authors, Pedro Berraondo.
Immunol Cell Biol, 2017 Feb 01; 95(4). PMID: 28138156
Highly Cited. Review.
Translation and Clinical Development of Bispecific T-cell Engaging Antibodies for Cancer Treatment.
T Yuraszeck, S Kasichayanula, J E Benjamin.
Clin Pharmacol Ther, 2017 Feb 10; 101(5). PMID: 28182247    Free PMC article.
Review.
Validation of Anti-Mouse PDL-1 Goat Polyclonal Antibody Staining with Mouse PDL-1 In Situ Hybridization on Adjacent Sections of Cell Pellets and Mouse Tumors.
Jacob Ricca, Mesruh Turkekul, +7 authors, Katia Manova-Todorova.
Methods Mol Biol, 2017 Feb 12; 1554. PMID: 28185198    Free PMC article.
Renal complications of immune checkpoint blockade.
Naoka Murakami, Shveta Motwani, Leonardo V Riella.
Curr Probl Cancer, 2017 Feb 13; 41(2). PMID: 28189263    Free PMC article.
Review.
CIITA-driven MHC class II expressing tumor cells can efficiently prime naive CD4+ TH cells in vivo and vaccinate the host against parental MHC-II-negative tumor cells.
Farah Bou Nasser Eddine, Greta Forlani, +3 authors, Roberto S Accolla.
Oncoimmunology, 2017 Feb 16; 6(1). PMID: 28197387    Free PMC article.
Immune Checkpoint Blockade Biology in Mouse Models of Glioblastoma.
Alan T Yeo, Alain Charest.
J Cell Biochem, 2017 Feb 24; 118(9). PMID: 28230277    Free PMC article.
Review.
Combining talimogene laherparepvec with immunotherapies in melanoma and other solid tumors.
Reinhard Dummer, Christoph Hoeller, Isabella Pezzani Gruter, Olivier Michielin.
Cancer Immunol Immunother, 2017 Feb 27; 66(6). PMID: 28238174    Free PMC article.
Review.
T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition.
Enfu Hui, Jeanne Cheung, +8 authors, Ronald D Vale.
Science, 2017 Mar 11; 355(6332). PMID: 28280247    Free PMC article.
Highly Cited.
Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent.
Alice O Kamphorst, Andreas Wieland, +17 authors, Rafi Ahmed.
Science, 2017 Mar 11; 355(6332). PMID: 28280249    Free PMC article.
Highly Cited.
Functio Laesa: Cancer Inflammation and Therapeutic Resistance.
Mingen Liu, Anusha Kalbasi, Gregory L Beatty.
J Oncol Pract, 2017 Mar 11; 13(3). PMID: 28282278    Free PMC article.
Review.
Nanomedicine approaches to improve cancer immunotherapy.
Hui Qiu, Yuanzeng Min, +2 authors, Andrew Z Wang.
Wiley Interdiscip Rev Nanomed Nanobiotechnol, 2017 Mar 16; 9(5). PMID: 28296286    Free PMC article.
Review.
PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity.
Vikram R Juneja, Kathleen A McGuire, +5 authors, Arlene H Sharpe.
J Exp Med, 2017 Mar 18; 214(4). PMID: 28302645    Free PMC article.
Highly Cited.
Spotlight on atezolizumab and its potential in the treatment of advanced urothelial bladder cancer.
Ahmet Murat Aydin, Solomon L Woldu, +5 authors, Laura-Maria Krabbe.
Onco Targets Ther, 2017 Mar 24; 10. PMID: 28331342    Free PMC article.
Review.
Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis.
Wouter Hendrickx, Ines Simeone, +14 authors, Davide Bedognetti.
Oncoimmunology, 2017 Mar 28; 6(2). PMID: 28344865    Free PMC article.
Highly Cited.
Clinical significance of T cell clonality and expression levels of immune-related genes in endometrial cancer.
Yuji Ikeda, Kazuma Kiyotani, +7 authors, Yusuke Nakamura.
Oncol Rep, 2017 Mar 31; 37(5). PMID: 28358435    Free PMC article.
Understanding the role of PD-L1/PD1 pathway blockade and autophagy in cancer therapy.
Marianela Robainas, Rafael Otano, Stephen Bueno, Sihem Ait-Oudhia.
Onco Targets Ther, 2017 Apr 04; 10. PMID: 28367063    Free PMC article.
Review.
A Novel Numerical Scoring System for Melanoma Tumor-infiltrating Lymphocytes Has Better Prognostic Value Than Standard Scoring.
Gerald Saldanha, Katarina Flatman, Kah Wee Teo, Mark Bamford.
Am J Surg Pathol, 2017 Apr 04; 41(7). PMID: 28368925    Free PMC article.
Avelumab, an Anti-Programmed Death-Ligand 1 Antibody, In Patients With Refractory Metastatic Urothelial Carcinoma: Results From a Multicenter, Phase Ib Study.
Andrea B Apolo, Jeffrey R Infante, +14 authors, James L Gulley.
J Clin Oncol, 2017 Apr 05; 35(19). PMID: 28375787    Free PMC article.
Highly Cited.
Role of Antigen Spread and Distinctive Characteristics of Immunotherapy in Cancer Treatment.
James L Gulley, Ravi A Madan, +4 authors, Charles G Drake.
J Natl Cancer Inst, 2017 Apr 05; 109(4). PMID: 28376158    Free PMC article.
Highly Cited. Review.
Tumor immunotherapy: drug-induced neoantigens (xenogenization) and immune checkpoint inhibitors.
Ornella Franzese, Francesco Torino, +5 authors, Stefania D'Atri.
Oncotarget, 2017 Apr 14; 8(25). PMID: 28404974    Free PMC article.
Review.
Applied Cancer Immunogenomics: Leveraging Neoantigen Discovery in Glioblastoma.
Tanner M Johanns, Gavin P Dunn.
Cancer J, 2017 Apr 15; 23(2). PMID: 28410300    Free PMC article.
Review.
Coordinating antigen cytosolic delivery and danger signaling to program potent cross-priming by micelle-based nanovaccine.
Zhida Liu, Chang Zhou, +10 authors, Wei Liang.
Cell Discov, 2017 Apr 19; 3. PMID: 28417012    Free PMC article.
Engineering Chimeric Antigen Receptor T-Cells for Racing in Solid Tumors: Don't Forget the Fuel.
Melita Irving, Romain Vuillefroy de Silly, +2 authors, George Coukos.
Front Immunol, 2017 Apr 20; 8. PMID: 28421069    Free PMC article.
Review.
Update on Programmed Death-1 and Programmed Death-Ligand 1 Inhibition in the Treatment of Advanced or Metastatic Non-Small Cell Lung Cancer.
Marco A J Iafolla, Rosalyn A Juergens.
Front Oncol, 2017 Apr 22; 7. PMID: 28428947    Free PMC article.
Review.
Immunotherapies in sarcoma: Updates and future perspectives.
Marwan Ghosn, Elie El Rassy, Hampig Raphael Kourie.
World J Clin Oncol, 2017 Apr 26; 8(2). PMID: 28439495    Free PMC article.
Review.
Landscape of Combination Immunotherapy and Targeted Therapy to Improve Cancer Management.
Leandro M Colli, Mitchell J Machiela, +5 authors, Stephen J Chanock.
Cancer Res, 2017 Apr 28; 77(13). PMID: 28446466    Free PMC article.
Novel role of granulocyte-macrophage colony-stimulating factor: antitumor effects through inhibition of epithelial-to-mesenchymal transition in esophageal cancer.
Jingxin Zhang, Qiqi Liu, +6 authors, Jiandong Zhang.
Onco Targets Ther, 2017 May 04; 10. PMID: 28461757    Free PMC article.
Wnt/beta-catenin pathway: modulating anticancer immune response.
Sachin Gopalkrishna Pai, Benedito A Carneiro, +6 authors, Francis Joseph Giles.
J Hematol Oncol, 2017 May 10; 10(1). PMID: 28476164    Free PMC article.
Highly Cited. Review.
Checkpoint inhibitors in hematological malignancies.
Chi Young Ok, Ken H Young.
J Hematol Oncol, 2017 May 10; 10(1). PMID: 28482851    Free PMC article.
Highly Cited. Review.
IDO, PTEN-expressing Tregs and control of antigen-presentation in the murine tumor microenvironment.
David H Munn, Madhav D Sharma, Theodore S Johnson, Paulo Rodriguez.
Cancer Immunol Immunother, 2017 May 11; 66(8). PMID: 28488123    Free PMC article.
Review.
In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy.
Sean P Arlauckas, Christopher S Garris, +9 authors, Mikael J Pittet.
Sci Transl Med, 2017 May 12; 9(389). PMID: 28490665    Free PMC article.
Highly Cited.
Functional analysis of rare variants in mismatch repair proteins augments results from computation-based predictive methods.
Sanjeevani Arora, Peter J Huwe, +8 authors, Erica A Golemis.
Cancer Biol Ther, 2017 May 12; 18(7). PMID: 28494185    Free PMC article.
Immune Checkpoint Inhibitors: An Innovation in Immunotherapy for the Treatment and Management of Patients with Cancer.
Jennifer Dine, RuthAnn Gordon, +2 authors, Margaret Barton-Burke.
Asia Pac J Oncol Nurs, 2017 May 16; 4(2). PMID: 28503645    Free PMC article.
Review.
Oncolytic measles virus encoding interleukin-12 mediates potent antitumor effects through T cell activation.
Rūta Veinalde, Christian Grossardt, +6 authors, Christine E Engeland.
Oncoimmunology, 2017 May 17; 6(4). PMID: 28507792    Free PMC article.
Mechanisms of Immune Tolerance in Leukemia and Lymphoma.
Emily K Curran, James Godfrey, Justin Kline.
Trends Immunol, 2017 May 18; 38(7). PMID: 28511816    Free PMC article.
Review.
Metabolomics of Therapy Response in Preclinical Glioblastoma: A Multi-Slice MRSI-Based Volumetric Analysis for Noninvasive Assessment of Temozolomide Treatment.
Nuria Arias-Ramos, Laura Ferrer-Font, +5 authors, Ana Paula Candiota.
Metabolites, 2017 May 20; 7(2). PMID: 28524099    Free PMC article.
Hallmarks of response to immune checkpoint blockade.
Alexandria P Cogdill, Miles C Andrews, Jennifer A Wargo.
Br J Cancer, 2017 May 20; 117(1). PMID: 28524159    Free PMC article.
Highly Cited. Review.
Prognostic value of KRAS mutation in advanced non-small-cell lung cancer treated with immune checkpoint inhibitors: A meta-analysis and review.
Jung Han Kim, Hyeong Su Kim, Bum Jun Kim.
Oncotarget, 2017 May 20; 8(29). PMID: 28525386    Free PMC article.
Review.
Intratumoral depletion of regulatory T cells using CD25-targeted photodynamic therapy in a mouse melanoma model induces antitumoral immune responses.
Dong Sun Oh, Heegon Kim, +4 authors, Heung Kyu Lee.
Oncotarget, 2017 May 26; 8(29). PMID: 28537894    Free PMC article.
5T4 oncofoetal glycoprotein: an old target for a novel prostate cancer immunotherapy.
Federica Cappuccini, Emily Pollock, +2 authors, Irina Redchenko.
Oncotarget, 2017 May 26; 8(29). PMID: 28537896    Free PMC article.
Combining radiotherapy with immunotherapy: the past, the present and the future.
Evert J Van Limbergen, Dirk K De Ruysscher, +8 authors, Philippe Lambin.
Br J Radiol, 2017 May 26; 90(1076). PMID: 28541096    Free PMC article.
Review.
Development of a versatile oncolytic virus platform for local intra-tumoural expression of therapeutic transgenes.
Nalini Marino, Sam Illingworth, +6 authors, Alice C N Brown.
PLoS One, 2017 May 26; 12(5). PMID: 28542292    Free PMC article.
Delivering safer immunotherapies for cancer.
Lauren Milling, Yuan Zhang, Darrell J Irvine.
Adv Drug Deliv Rev, 2017 May 27; 114. PMID: 28545888    Free PMC article.
Highly Cited. Review.
ERBB3: A potential serum biomarker for early detection and therapeutic target for devil facial tumour 1 (DFT1).
Dane A Hayes, Dale A Kunde, +3 authors, Elizabeth T Snow.
PLoS One, 2017 Jun 08; 12(6). PMID: 28591206    Free PMC article.
Induction of cathepsin B by the CXCR3 chemokines CXCL9 and CXCL10 in human breast cancer cells.
Holger Bronger, Anne Karge, +5 authors, Manfred Schmitt.
Oncol Lett, 2017 Jun 11; 13(6). PMID: 28599423    Free PMC article.
Metabolism shapes the tumor microenvironment.
Miguel Reina-Campos, Jorge Moscat, Maria Diaz-Meco.
Curr Opin Cell Biol, 2017 Jun 13; 48. PMID: 28605656    Free PMC article.
Review.
Phase II Trial of Atezolizumab As First-Line or Subsequent Therapy for Patients With Programmed Death-Ligand 1-Selected Advanced Non-Small-Cell Lung Cancer (BIRCH).
Solange Peters, Scott Gettinger, +25 authors, Enriqueta Felip.
J Clin Oncol, 2017 Jun 14; 35(24). PMID: 28609226    Free PMC article.
Highly Cited.
Autophagic Mechanism in Anti-Cancer Immunity: Its Pros and Cons for Cancer Therapy.
Ying-Ying Li, Lynn G Feun, +6 authors, Niramol Savaraj.
Int J Mol Sci, 2017 Jun 21; 18(6). PMID: 28629173    Free PMC article.
Review.
The era of bioengineering: how will this affect the next generation of cancer immunotherapy?
Michele Graciotti, Cristiana Berti, Harm-Anton Klok, Lana Kandalaft.
J Transl Med, 2017 Jun 21; 15(1). PMID: 28629381    Free PMC article.
Review.
Polyfunctional response by ImmTAC (IMCgp100) redirected CD8+ and CD4+ T cells.
Caroline Boudousquie, Giovanna Bossi, +3 authors, Namir J Hassan.
Immunology, 2017 Jun 24; 152(3). PMID: 28640942    Free PMC article.
IFN-γ-related mRNA profile predicts clinical response to PD-1 blockade.
Mark Ayers, Jared Lunceford, +12 authors, Terrill K McClanahan.
J Clin Invest, 2017 Jun 27; 127(8). PMID: 28650338    Free PMC article.
Highly Cited.
Immunotherapy biomarkers 2016: overcoming the barriers.
James L Gulley, Jay A Berzofsky, +18 authors, Lisa H Butterfield.
J Immunother Cancer, 2017 Jun 28; 5(1). PMID: 28653584    Free PMC article.
Addressing current challenges in cancer immunotherapy with mathematical and computational modelling.
Anna Konstorum, Anthony T Vella, Adam J Adler, Reinhard C Laubenbacher.
J R Soc Interface, 2017 Jul 01; 14(131). PMID: 28659410    Free PMC article.
Review.
Partial exhaustion of CD8 T cells and clinical response to teplizumab in new-onset type 1 diabetes.
S Alice Long, Jerill Thorpe, +7 authors, Peter S Linsley.
Sci Immunol, 2017 Jul 01; 1(5). PMID: 28664195    Free PMC article.
Highly Cited.
Novel Therapies for Acute Myeloid Leukemia: Are We Finally Breaking the Deadlock?
Maximilian Stahl, Benjamin Y Lu, Tae Kon Kim, Amer M Zeidan.
Target Oncol, 2017 Jul 01; 12(4). PMID: 28664386
Review.
Combining Local Immunotoxins Targeting Mesothelin with CTLA-4 Blockade Synergistically Eradicates Murine Cancer by Promoting Anticancer Immunity.
Yasmin Leshem, James O'Brien, +8 authors, Ira Pastan.
Cancer Immunol Res, 2017 Jul 05; 5(8). PMID: 28674083    Free PMC article.
New B7 Family Checkpoints in Human Cancers.
Ling Ni, Chen Dong.
Mol Cancer Ther, 2017 Jul 07; 16(7). PMID: 28679835    Free PMC article.
Review.
Novel immunotherapy in metastatic renal cell carcinoma.
Yang Hyun Cho, Myung Soo Kim, Ho Seok Chung, Eu Chang Hwang.
Investig Clin Urol, 2017 Jul 07; 58(4). PMID: 28681030    Free PMC article.
Review.
Oncolytic viruses: adenoviruses.
Julia Niemann, Florian Kühnel.
Virus Genes, 2017 Jul 14; 53(5). PMID: 28702840
Review.
Predictive biomarkers of immunotherapy for non-small cell lung cancer: results from an Experts Panel Meeting of the Italian Association of Thoracic Oncology.
Cesare Gridelli, Andrea Ardizzoni, +5 authors, Filippo De Marinis.
Transl Lung Cancer Res, 2017 Jul 18; 6(3). PMID: 28713682    Free PMC article.
Review.
Atezolizumab for the treatment of non-small cell lung cancer.
Fernando C Santini, Charles M Rudin.
Expert Rev Clin Pharmacol, 2017 Jul 18; 10(9). PMID: 28714780    Free PMC article.
Review.
Highlights of the 31st annual meeting of the Society for Immunotherapy of Cancer (SITC), 2016.
James L Gulley, Elizabeth A Repasky, Laura S Wood, Lisa H Butterfield.
J Immunother Cancer, 2017 Jul 19; 5(1). PMID: 28716068    Free PMC article.
Review.
NLRC5/CITA: A Key Player in Cancer Immune Surveillance.
Sayuri Yoshihama, Saptha Vijayan, Tabasum Sidiq, Koichi S Kobayashi.
Trends Cancer, 2017 Jul 19; 3(1). PMID: 28718425    Free PMC article.
Review.
Cytokine-Induced Killer Cells As Pharmacological Tools for Cancer Immunotherapy.
Xingchun Gao, Yajing Mi, +4 authors, Weilin Jin.
Front Immunol, 2017 Jul 22; 8. PMID: 28729866    Free PMC article.
Review.
Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer.
Manav Korpal, Xiaoling Puyang, +36 authors, Ping Zhu.
Nat Commun, 2017 Jul 26; 8(1). PMID: 28740126    Free PMC article.
Does Regular Exercise Counter T Cell Immunosenescence Reducing the Risk of Developing Cancer and Promoting Successful Treatment of Malignancies?
James E Turner, Patricia C Brum.
Oxid Med Cell Longev, 2017 Jul 29; 2017. PMID: 28751932    Free PMC article.
Review.
PD-1 and PD-L1 as emerging therapeutic targets in gastric cancer: current evidence.
Phu N Tran, Sarmen Sarkissian, Joseph Chao, Samuel J Klempner.
Gastrointest Cancer, 2017 Aug 02; 7. PMID: 28757801    Free PMC article.
Heterogeneity of tumor-infiltrating lymphocytes ascribed to local immune status rather than neoantigens by multi-omics analysis of glioblastoma multiforme.
Lin Feng, Haipeng Qian, +8 authors, Kaitai Zhang.
Sci Rep, 2017 Aug 02; 7(1). PMID: 28761058    Free PMC article.
Checkpoint inhibitors in the treatment of urological malignancies.
Lazar S Popovic, Gorana Matovina-Brko, Maja Popovic.
ESMO Open, 2017 Aug 02; 2(2). PMID: 28761743    Free PMC article.
Review.
Contrasting effects of cyclophosphamide on anti-CTL-associated protein 4 blockade therapy in two mouse tumor models.
Yuichi Iida, Nanae Harashima, +3 authors, Mamoru Harada.
Cancer Sci, 2017 Aug 09; 108(10). PMID: 28787548    Free PMC article.
Direct Loading of iTEP-Delivered CTL Epitope onto MHC Class I Complexes on the Dendritic Cell Surface.
Shuyun Dong, Peng Wang, Peng Zhao, Mingnan Chen.
Mol Pharm, 2017 Aug 10; 14(10). PMID: 28789525    Free PMC article.
PD-L1 and gastric cancer prognosis: A systematic review and meta-analysis.
Lihu Gu, Manman Chen, +7 authors, Xianfa Wang.
PLoS One, 2017 Aug 11; 12(8). PMID: 28796808    Free PMC article.
Highly Cited. Systematic Review.
Enhancement of Adjuvant Functions of Natural Killer T Cells Using Nanovector Delivery Systems: Application in Anticancer Immune Therapy.
Reem Ghinnagow, Luis Javier Cruz, +2 authors, François Trottein.
Front Immunol, 2017 Aug 12; 8. PMID: 28798749    Free PMC article.
Review.
Clinical significance of tumor-infiltrating lymphocytes for gastric cancer in the era of immunology.
Byung Woog Kang, Jong Gwang Kim, +2 authors, An Na Seo.
World J Gastrointest Oncol, 2017 Aug 16; 9(7). PMID: 28808502    Free PMC article.
Review.
Immune Modulation Therapy and Imaging: Workshop Report.
Anthony F Shields, Paula M Jacobs, +11 authors, Lalitha K Shankar.
J Nucl Med, 2017 Aug 19; 59(3). PMID: 28818991    Free PMC article.
Phase II Trial of Adjuvant Immunotherapy with Autologous Tumor-derived Gp96 Vaccination in Patients with Gastric Cancer.
Kecheng Zhang, Zheng Peng, +10 authors, Lin Chen.
J Cancer, 2017 Aug 19; 8(10). PMID: 28819380    Free PMC article.
Enlighting the Shadow for Advanced Hepatocellular Carcinoma: Immunotherapy with Immune Checkpoint Inhibitors.
Berksoy Sahin.
J Gastrointest Cancer, 2017 Aug 25; 48(3). PMID: 28836129
Review.
Modified Vaccinia virus Ankara-based vaccines in the era of personalized immunotherapy of cancer.
Kaïdre Bendjama, Eric Quemeneur.
Hum Vaccin Immunother, 2017 Aug 29; 13(9). PMID: 28846477    Free PMC article.
Use of programmed cell death protein ligand 1 assay to predict the outcomes of non-small cell lung cancer patients treated with immune checkpoint inhibitors.
Carmelo Tibaldi, Alice Lunghi, Editta Baldini.
World J Clin Oncol, 2017 Aug 30; 8(4). PMID: 28848698    Free PMC article.
Review.
CTLA-4/CD80 pathway regulates T cell infiltration into pancreatic cancer.
Fee Bengsch, Dawson M Knoblock, +2 authors, Gregory L Beatty.
Cancer Immunol Immunother, 2017 Sep 01; 66(12). PMID: 28856392    Free PMC article.
Head and neck cancer: improving outcomes with a multidisciplinary approach.
Cristiana Lo Nigro, Nerina Denaro, Anna Merlotti, Marco Merlano.
Cancer Manag Res, 2017 Sep 02; 9. PMID: 28860859    Free PMC article.
Review.
Immune Checkpoint Blockers and Ovarian Cancer.
Chinmoy K Bose.
Indian J Med Paediatr Oncol, 2017 Sep 14; 38(2). PMID: 28900328    Free PMC article.
Review.
Tim-3, Lag-3, and TIGIT.
Nicole Joller, Vijay K Kuchroo.
Curr Top Microbiol Immunol, 2017 Sep 14; 410. PMID: 28900677    Free PMC article.
Review.
MEK inhibition and immune responses in advanced melanoma.
Reinhard Dummer, Egle Ramelyte, +3 authors, Peter Koelblinger.
Oncoimmunology, 2017 Sep 19; 6(8). PMID: 28919996    Free PMC article.
Review.
Viral based vaccine TG4010 induces broadening of specific immune response and improves outcome in advanced NSCLC.
Caroline Tosch, Bérangère Bastien, +7 authors, Xavier Préville.
J Immunother Cancer, 2017 Sep 20; 5(1). PMID: 28923084    Free PMC article.
Sequential administration of MVA-based vaccines and PD-1/PD-L1-blocking antibodies confers measurable benefits on tumor growth and survival: Preclinical studies with MVA-βGal and MVA-MUC1 (TG4010) in a murine tumor model.
Christelle Remy-Ziller, Christine Thioudellet, +8 authors, Karola Rittner.
Hum Vaccin Immunother, 2017 Sep 20; 14(1). PMID: 28925793    Free PMC article.
Roles for Innate Immunity in Combination Immunotherapies.
Kelly D Moynihan, Darrell J Irvine.
Cancer Res, 2017 Sep 21; 77(19). PMID: 28928130    Free PMC article.
Review.
Co-delivery of the NKT agonist α-galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses.
Reem Ghinnagow, Julie De Meester, +12 authors, François Trottein.
Oncoimmunology, 2017 Sep 22; 6(9). PMID: 28932640    Free PMC article.
[Novel Immuno-oncology Therapy: Current Status of Clinical Research and Prospect of Application].
Shijia Zhang, Shengxiang Ren.
Zhongguo Fei Ai Za Zhi, 2017 Sep 25; 20(9). PMID: 28935020    Free PMC article.
Review.
Significance of evaluating tumor-infiltrating lymphocytes (TILs) and programmed cell death-ligand 1 (PD-L1) expression in breast cancer.
Sasagu Kurozumi, Takaaki Fujii, +4 authors, Hiroyuki Kuwano.
Med Mol Morphol, 2017 Sep 25; 50(4). PMID: 28936553
Review.
Enhancing cancer immunotherapy through nanotechnology-mediated tumor infiltration and activation of immune cells.
Haifa Shen, Tong Sun, +4 authors, Mauro Ferrari.
Semin Immunol, 2017 Sep 28; 34. PMID: 28947107    Free PMC article.
Review.
Atezolizumab in platinum-treated locally advanced or metastatic urothelial carcinoma: post-progression outcomes from the phase II IMvigor210 study.
A Necchi, R W Joseph, +9 authors, J E Rosenberg.
Ann Oncol, 2017 Sep 28; 28(12). PMID: 28950298    Free PMC article.
Toward Personalized Peptide-Based Cancer Nanovaccines: A Facile and Versatile Synthetic Approach.
Hamilton Kakwere, Elizabeth S Ingham, +6 authors, Katherine W Ferrara.
Bioconjug Chem, 2017 Sep 29; 28(11). PMID: 28956907    Free PMC article.
Nanomaterials for cancer immunotherapy.
Wantong Song, Sara N Musetti, Leaf Huang.
Biomaterials, 2017 Sep 30; 148. PMID: 28961532    Free PMC article.
Review.
Randomized, Open-Label Phase II Study Evaluating the Efficacy and Safety of Talimogene Laherparepvec in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced, Unresectable Melanoma.
Jason Chesney, Igor Puzanov, +15 authors, Howard L Kaufman.
J Clin Oncol, 2017 Oct 06; 36(17). PMID: 28981385    Free PMC article.
Highly Cited.
Tethered-variable CL bispecific IgG: an antibody platform for rapid bispecific antibody screening.
Hok Seon Kim, Diana Ronai Dunshee, +7 authors, Christoph Spiess.
Protein Eng Des Sel, 2017 Oct 07; 30(9). PMID: 28985411    Free PMC article.
CD4 and CD8 T lymphocyte interplay in controlling tumor growth.
Dmitrij Ostroumov, Nora Fekete-Drimusz, +2 authors, Norman Woller.
Cell Mol Life Sci, 2017 Oct 17; 75(4). PMID: 29032503    Free PMC article.
Review.
The immune system in cancer metastasis: friend or foe?
Louise M E Janssen, Emma E Ramsay, Craig D Logsdon, Willem W Overwijk.
J Immunother Cancer, 2017 Oct 19; 5(1). PMID: 29037250    Free PMC article.
Highly Cited. Review.
A nonimmune function of T cells in promoting lung tumor progression.
Jesse A Green, Nicholas Arpaia, +2 authors, Alexander Y Rudensky.
J Exp Med, 2017 Oct 19; 214(12). PMID: 29038367    Free PMC article.
Tumor-infiltrating CD8+ lymphocytes predict different clinical outcomes in organ- and non-organ-confined urothelial carcinoma of the bladder following radical cystectomy.
Shiqiang Zhang, Jun Wang, Xinyu Zhang, Fangjian Zhou.
PeerJ, 2017 Oct 19; 5. PMID: 29043112    Free PMC article.
Cytokeratin7 expression in histologic and cytologic specimens of cystic neck metastasis from HPV positive squamous cell carcinoma of the tonsil: A case report.
Yong Kyun Cho, Seung Ju Lee, +2 authors, Hojung Lee.
Diagn Cytopathol, 2017 Oct 20; 46(4). PMID: 29048728    Free PMC article.
Immunomodulatory and antitumor effects of type I interferons and their application in cancer therapy.
Ruan F V Medrano, Aline Hunger, +2 authors, Bryan E Strauss.
Oncotarget, 2017 Oct 21; 8(41). PMID: 29050360    Free PMC article.
Review.
Targeting immunosuppressive adenosine in cancer.
Dipti Vijayan, Arabella Young, Michele W L Teng, Mark J Smyth.
Nat Rev Cancer, 2017 Oct 24; 17(12). PMID: 29059149
Highly Cited. Review.
Intratumoural PD-L1 expression is associated with worse survival of patients with Epstein-Barr virus-associated gastric cancer.
An Na Seo, Byung Woog Kang, +8 authors, Jong Gwang Kim.
Br J Cancer, 2017 Oct 27; 117(12). PMID: 29073638    Free PMC article.
Desired Turbulence? Gut-Lung Axis, Immunity, and Lung Cancer.
Rea Bingula, Marc Filaire, +5 authors, Edith Filaire.
J Oncol, 2017 Oct 28; 2017. PMID: 29075294    Free PMC article.
Review.
Overcoming resistance to targeted therapy with immunotherapy and combination therapy for metastatic melanoma.
Hilary R Keller, Xin Zhang, +2 authors, James W Wells.
Oncotarget, 2017 Nov 02; 8(43). PMID: 29088901    Free PMC article.
Review.
Cardiotoxicity of immune checkpoint inhibitors.
Gilda Varricchi, Maria Rosaria Galdiero, +5 authors, Carlo Gabriele Tocchetti.
ESMO Open, 2017 Nov 07; 2(4). PMID: 29104763    Free PMC article.
Highly Cited. Review.
Image-guided dendritic cell-based vaccine immunotherapy in murine carcinoma models.
Bin Wang, Chong Sun, +9 authors, Zhuoli Zhang.
Am J Transl Res, 2017 Nov 10; 9(10). PMID: 29118918    Free PMC article.
Review.
Immune evasion mechanisms and immune checkpoint inhibition in advanced merkel cell carcinoma.
Dirk Schadendorf, Paul Nghiem, +5 authors, Howard L Kaufman.
Oncoimmunology, 2017 Nov 11; 6(10). PMID: 29123950    Free PMC article.
Review.
T cell receptor sequencing of early-stage breast cancer tumors identifies altered clonal structure of the T cell repertoire.
John F Beausang, Amanda J Wheeler, +4 authors, Stephen R Quake.
Proc Natl Acad Sci U S A, 2017 Nov 16; 114(48). PMID: 29138313    Free PMC article.
Future perspectives in melanoma research "Melanoma Bridge", Napoli, November 30th-3rd December 2016.
Paolo A Ascierto, Sanjiv S Agarwala, +20 authors, Magdalena Thurin.
J Transl Med, 2017 Nov 18; 15(1). PMID: 29145885    Free PMC article.
Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses.
Aránzazu Cruz-Adalia, Guillermo Ramirez-Santiago, +10 authors, Esteban Veiga.
Nat Commun, 2017 Nov 18; 8(1). PMID: 29147022    Free PMC article.
PD-L1 expression on immune cells is a favorable prognostic factor for vulvar squamous cell carcinoma patients.
Jacek J Sznurkowski, Anton Żawrocki, +2 authors, Wojciech Biernat.
Oncotarget, 2017 Nov 23; 8(52). PMID: 29163797    Free PMC article.
Prognostic value of PD-L1 expression in combination with CD8+ TILs density in patients with surgically resected non-small cell lung cancer.
Hui Yang, Jinpeng Shi, +11 authors, Caicun Zhou.
Cancer Med, 2017 Nov 24; 7(1). PMID: 29168339    Free PMC article.
Immune checkpoints, their control by immunotherapy and ovarian cancer.
Chinmoy K Bose.
Contemp Oncol (Pozn), 2017 Nov 29; 21(3). PMID: 29180924    Free PMC article.
Review.
Altered Leukocyte Sphingolipid Pathway in Breast Cancer.
Larissa P Maia, Paula S Santos, +6 authors, Luiz Ricardo Goulart.
Int J Mol Sci, 2017 Dec 01; 18(12). PMID: 29186783    Free PMC article.
Trial Watch: Immunostimulatory monoclonal antibodies for oncological indications.
Mariona Cabo, Rienk Offringa, +3 authors, Lorenzo Galluzzi.
Oncoimmunology, 2017 Dec 07; 6(12). PMID: 29209572    Free PMC article.
Review.
Impact of cavitron ultrasonic surgical aspirator (CUSA) and bipolar radiofrequency device (Habib-4X) based hepatectomy for hepatocellular carcinoma on tumour recurrence and disease-free survival.
Kai-Wen Huang, Po-Huang Lee, +3 authors, Nagy Habib.
Oncotarget, 2017 Dec 08; 8(55). PMID: 29212179    Free PMC article.
Drug development in the era of precision medicine.
Sarah A Dugger, Adam Platt, David B Goldstein.
Nat Rev Drug Discov, 2017 Dec 09; 17(3). PMID: 29217837    Free PMC article.
Highly Cited. Review.
Towards personalized, tumour-specific, therapeutic vaccines for cancer.
Zhuting Hu, Patrick A Ott, Catherine J Wu.
Nat Rev Immunol, 2017 Dec 12; 18(3). PMID: 29226910    Free PMC article.
Highly Cited. Review.
Navigating the "No Man's Land" of TKI-Failed EGFR-Mutated Non-Small Cell Lung Cancer (NSCLC): A Review.
Bryan Oronsky, Patrick Ma, +5 authors, Corey A Carter.
Neoplasia, 2017 Dec 12; 20(1). PMID: 29227909    Free PMC article.
Review.
Neoantigens Generated by Individual Mutations and Their Role in Cancer Immunity and Immunotherapy.
Mirjana Efremova, Francesca Finotello, Dietmar Rieder, Zlatko Trajanoski.
Front Immunol, 2017 Dec 14; 8. PMID: 29234329    Free PMC article.
Highly Cited. Review.
Immunotherapies for malignant glioma.
Vassiliki A Boussiotis, Alain Charest.
Oncogene, 2017 Dec 16; 37(9). PMID: 29242608    Free PMC article.
Review.
The immunomodulatory activities of licorice polysaccharides (Glycyrrhiza uralensis Fisch.) in CT 26 tumor-bearing mice.
Peter Amwoga Ayeka, YuHong Bian, Peter Mwitari Githaiga, Ying Zhao.
BMC Complement Altern Med, 2017 Dec 17; 17(1). PMID: 29246138    Free PMC article.
Informatics for cancer immunotherapy.
J Hammerbacher, A Snyder.
Ann Oncol, 2017 Dec 19; 28(suppl_12). PMID: 29253114    Free PMC article.
Review.
Management of relapsed and refractory multiple myeloma: novel agents, antibodies, immunotherapies and beyond.
C S Chim, S K Kumar, +7 authors, K C Anderson.
Leukemia, 2017 Dec 20; 32(2). PMID: 29257139    Free PMC article.
Highly Cited. Review.
The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy.
Jodi A McKenzie, Rina M Mbofung, +25 authors, Patrick Hwu.
J Natl Cancer Inst, 2017 Dec 22; 110(7). PMID: 29267866    Free PMC article.
Recent Successes and Future Directions in Immunotherapy of Cutaneous Melanoma.
Hassan Sadozai, Thomas Gruber, Robert Emil Hunger, Mirjam Schenk.
Front Immunol, 2017 Dec 26; 8. PMID: 29276510    Free PMC article.
Review.
Immune Checkpoint Inhibitor-Associated Type 1 Diabetes Mellitus: Case Series, Review of the Literature, and Optimal Management.
Jonathan Kapke, Zachary Shaheen, +2 authors, Stuart Wong.
Case Rep Oncol, 2017 Dec 28; 10(3). PMID: 29279690    Free PMC article.
Immune system and melanoma biology: a balance between immunosurveillance and immune escape.
Anna Passarelli, Francesco Mannavola, +2 authors, Francesco Silvestris.
Oncotarget, 2017 Dec 30; 8(62). PMID: 29285320    Free PMC article.
Review.
Activity and Immune Correlates of a Programmed Death-1 Blockade Antibody in the treatment of Refractory Solid Tumors.
Chang Jiang, Xiuyu Cai, +3 authors, Liangping Xia.
J Cancer, 2018 Jan 02; 9(1). PMID: 29290787    Free PMC article.
FOXOs in cancer immunity: Knowns and unknowns.
Youcai Deng, Fangjie Wang, Tiffany Hughes, Jianhua Yu.
Semin Cancer Biol, 2018 Jan 09; 50. PMID: 29309928    Free PMC article.
Review.
Perspective on immune oncology with liquid biopsy, peripheral blood mononuclear cells, and microbiome with non-invasive biomarkers in cancer patients.
A Mitsuhashi, Y Okuma.
Clin Transl Oncol, 2018 Jan 10; 20(8). PMID: 29313208
Review.
TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer.
Álvaro de Mingo Pulido, Alycia Gardner, +5 authors, Brian Ruffell.
Cancer Cell, 2018 Jan 10; 33(1). PMID: 29316433    Free PMC article.
Highly Cited.
Using Genome Sequence to Enable the Design of Medicines and Chemical Probes.
Alicia J Angelbello, Jonathan L Chen, +3 authors, Matthew D Disney.
Chem Rev, 2018 Jan 13; 118(4). PMID: 29322778    Free PMC article.
Highly Cited. Review.
Anti-Programmed Cell Death 1/Ligand 1 (PD-1/PD-L1) Antibodies for the Treatment of Urothelial Carcinoma: State of the Art and Future Development.
Thomas Powles, Andrea Necchi, +2 authors, Andrea B Apolo.
Clin Genitourin Cancer, 2018 Jan 13; 16(2). PMID: 29325739    Free PMC article.
Review.
Tumor Immunology and Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer.
Chi Young Jung, Scott J Antonia.
Tuberc Respir Dis (Seoul), 2018 Jan 15; 81(1). PMID: 29332322    Free PMC article.
Review.
Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors.
Madhav D Sharma, Paulo C Rodriguez, +16 authors, David H Munn.
Immunity, 2018 Jan 19; 48(1). PMID: 29343444    Free PMC article.
Highly Cited.
PD-L1 expression in tumor tissue and peripheral blood of patients with oral squamous cell carcinoma.
Manuel Weber, Falk Wehrhan, +5 authors, Jutta Ries.
Oncotarget, 2018 Jan 20; 8(68). PMID: 29348848    Free PMC article.
Immune Checkpoint Blockade for Breast Cancer.
April Swoboda, Rita Nanda.
Cancer Treat Res, 2018 Jan 20; 173. PMID: 29349763    Free PMC article.
Review.
OMIP-044: 28-color immunophenotyping of the human dendritic cell compartment.
Florian Mair, Martin Prlic.
Cytometry A, 2018 Jan 23; 93(4). PMID: 29356334    Free PMC article.
Chemotherapy weakly contributes to predicted neoantigen expression in ovarian cancer.
Timothy O'Donnell, Elizabeth L Christie, +5 authors, Jeff Hammerbacher.
BMC Cancer, 2018 Jan 24; 18(1). PMID: 29357823    Free PMC article.
The ascent of immune checkpoint inhibitors: is the understudy ready for a leading role?
Amy L Cummings, Edward B Garon.
Cancer Biol Med, 2018 Jan 27; 14(4). PMID: 29372100    Free PMC article.
Precision Immuno-Oncology: Prospects of Individualized Immunotherapy for Pancreatic Cancer.
Jiajia Zhang, Christopher L Wolfgang, Lei Zheng.
Cancers (Basel), 2018 Feb 02; 10(2). PMID: 29385739    Free PMC article.
Review.
Bringing the next Generation of Immuno-Oncology Biomarkers to the Clinic.
Alessandra Cesano, Sarah Warren.
Biomedicines, 2018 Feb 03; 6(1). PMID: 29393888    Free PMC article.
Highly Cited. Review.
The tumour glyco-code as a novel immune checkpoint for immunotherapy.
Ernesto RodrÍguez, Sjoerd T T Schetters, Yvette van Kooyk.
Nat Rev Immunol, 2018 Feb 06; 18(3). PMID: 29398707
Highly Cited. Review.
PD-L1 and PD-1 and characterization of tumor-infiltrating lymphocytes in high grade sarcomas of soft tissue - prognostic implications and rationale for immunotherapy.
Melanie Boxberg, Katja Steiger, +6 authors, Katja Specht.
Oncoimmunology, 2018 Feb 06; 7(3). PMID: 29399389    Free PMC article.
A safe and highly efficient tumor-targeted type I interferon immunotherapy depends on the tumor microenvironment.
Anje Cauwels, Sandra Van Lint, +11 authors, Jan Tavernier.
Oncoimmunology, 2018 Feb 06; 7(3). PMID: 29399401    Free PMC article.
From a Patient Advocate's Perspective: Does Cancer Immunotherapy Represent a Paradigm Shift?
Debra L Madden.
Curr Oncol Rep, 2018 Feb 08; 20(1). PMID: 29411148
Review.
Durvalumab: an investigational anti-PD-L1 monoclonal antibody for the treatment of urothelial carcinoma.
Izak Faiena, Amy L Cummings, +3 authors, Alexandra Drakaki.
Drug Des Devel Ther, 2018 Feb 09; 12. PMID: 29416316    Free PMC article.
Review.
Comprehensive immunotherapy combined with intratumoral injection of zoledronate-pulsed dendritic cells, intravenous adoptive activated T lymphocyte and gemcitabine in unresectable locally advanced pancreatic carcinoma: a phase I/II trial.
Yoshiki Hirooka, Hiroki Kawashima, +5 authors, Hidemi Goto.
Oncotarget, 2018 Feb 09; 9(2). PMID: 29416816    Free PMC article.
Cancer Immunotherapy: Factors Important for the Evaluation of Safety in Nonclinical Studies.
Danuta J Herzyk, Helen G Haggerty.
AAPS J, 2018 Feb 09; 20(2). PMID: 29417397
Review.
Atezolizumab (MPDL3280A) Monotherapy for Patients With Metastatic Urothelial Cancer: Long-term Outcomes From a Phase 1 Study.
Daniel P Petrylak, Thomas Powles, +10 authors, Nicholas J Vogelzang.
JAMA Oncol, 2018 Feb 10; 4(4). PMID: 29423515    Free PMC article.
Highly Cited.
DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation.
Qian Xiao, Jibo Wu, +14 authors, Dianqing Wu.
Nat Med, 2018 Feb 13; 24(3). PMID: 29431745    Free PMC article.
Highly Cited.
Improving immunotherapy outcomes with anti-angiogenic treatments and vice versa.
Kabir A Khan, Robert S Kerbel.
Nat Rev Clin Oncol, 2018 Feb 13; 15(5). PMID: 29434333
Highly Cited. Review.
TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.
Sanjeev Mariathasan, Shannon J Turley, +39 authors, Thomas Powles.
Nature, 2018 Feb 15; 554(7693). PMID: 29443960    Free PMC article.
Highly Cited.
Engineering chimeric antigen receptor-T cells for cancer treatment.
Baixin Ye, Creed M Stary, +3 authors, Xiaoxing Xiong.
Mol Cancer, 2018 Feb 17; 17(1). PMID: 29448937    Free PMC article.
Review.
Quiescent Tissue Stem Cells Evade Immune Surveillance.
Judith Agudo, Eun Sook Park, +8 authors, Brian D Brown.
Immunity, 2018 Feb 22; 48(2). PMID: 29466757    Free PMC article.
Highly Cited.
A comparative study of PD-L1 immunohistochemical assays with four reliable antibodies in thymic carcinoma.
Tadashi Sakane, Takayuki Murase, +11 authors, Hiroshi Inagaki.
Oncotarget, 2018 Feb 23; 9(6). PMID: 29467945    Free PMC article.
Radiation and PD-(L)1 treatment combinations: immune response and dose optimization via a predictive systems model.
Yuri Kosinsky, Simon J Dovedi, +6 authors, Gabriel Helmlinger.
J Immunother Cancer, 2018 Mar 01; 6(1). PMID: 29486799    Free PMC article.
Analysis of response rate with ANTI PD1/PD-L1 monoclonal antibodies in advanced solid tumors: a meta-analysis of randomized clinical trials.
Alberto Carretero-González, David Lora, +6 authors, Guillermo de Velasco.
Oncotarget, 2018 Mar 02; 9(9). PMID: 29492229    Free PMC article.
Combination nivolumab with transcatheter arterial chemoembolization for clinical remission of small cell lung cancer: A case report.
Ziwei Guo, Chao Meng, +2 authors, Jun Liang.
Thorac Cancer, 2018 Mar 03; 9(5). PMID: 29498219    Free PMC article.
Epigenetic Therapeutics and Their Impact in Immunotherapy of Lung Cancer.
Ju Hwan Cho, Filiz Oezkan, +3 authors, Kai He.
Curr Pharmacol Rep, 2018 Mar 06; 3(6). PMID: 29503796    Free PMC article.
Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges.
Dai Fukumura, Jonas Kloepper, +2 authors, Rakesh K Jain.
Nat Rev Clin Oncol, 2018 Mar 07; 15(5). PMID: 29508855    Free PMC article.
Highly Cited. Review.
Randomized phase II trial of autologous dendritic cell vaccines versus autologous tumor cell vaccines in metastatic melanoma: 5-year follow up and additional analyses.
Robert O Dillman, Andrew N Cornforth, +3 authors, Carol Depriest.
J Immunother Cancer, 2018 Mar 08; 6(1). PMID: 29510745    Free PMC article.
Development of Molecularly Targeted Agents and Immunotherapies in Glioblastoma: A Personalized Approach.
Niamh Coleman, Malaka Ameratunga, Juanita Lopez.
Clin Med Insights Oncol, 2018 Mar 08; 12. PMID: 29511362    Free PMC article.
Review.
A dual-function epidermal growth factor receptor pathway substrate 8 (Eps8)-derived peptide exhibits a potent cytotoxic T lymphocyte-activating effect and a specific inhibitory activity.
Xiaoling Xie, Weijun Zhou, +3 authors, Yuhua Li.
Cell Death Dis, 2018 Mar 09; 9(3). PMID: 29515106    Free PMC article.
Checks and Balances in Autoimmune Vasculitis.
Rebeca Hid Cadena, Wayel H Abdulahad, +4 authors, Elisabeth Brouwer.
Front Immunol, 2018 Mar 10; 9. PMID: 29520282    Free PMC article.
Review.
CD169-positive sinus macrophages in the lymph nodes determine bladder cancer prognosis.
Touko Asano, Koji Ohnishi, +6 authors, Yoshihiro Komohara.
Cancer Sci, 2018 Mar 10; 109(5). PMID: 29520898    Free PMC article.
Targeting Tumor Metabolism: A New Challenge to Improve Immunotherapy.
Soumaya Kouidhi, Farhat Ben Ayed, Amel Benammar Elgaaied.
Front Immunol, 2018 Mar 13; 9. PMID: 29527212    Free PMC article.
Highly Cited. Review.
Comprehensive immunohistochemical analysis of PD-L1 shows scarce expression in castration-resistant prostate cancer.
Christian D Fankhauser, Peter J Schüffler, +8 authors, Peter J Wild.
Oncotarget, 2018 Mar 15; 9(12). PMID: 29535806    Free PMC article.
Quantifying tumor-infiltrating immune cells from transcriptomics data.
Francesca Finotello, Zlatko Trajanoski.
Cancer Immunol Immunother, 2018 Mar 16; 67(7). PMID: 29541787    Free PMC article.
Highly Cited. Review.
Potent Immune Modulation by MEDI6383, an Engineered Human OX40 Ligand IgG4P Fc Fusion Protein.
Michael D Oberst, Catherine Augé, +19 authors, Scott A Hammond.
Mol Cancer Ther, 2018 Mar 17; 17(5). PMID: 29545330    Free PMC article.
The serum-based VeriStrat® test is associated with proinflammatory reactants and clinical outcome in non-small cell lung cancer patients.
Mary Jo Fidler, Cristina L Fhied, +7 authors, Jeffrey A Borgia.
BMC Cancer, 2018 Mar 22; 18(1). PMID: 29558888    Free PMC article.
A phase I/Ib study of OTSGC-A24 combined peptide vaccine in advanced gastric cancer.
Raghav Sundar, Sun Young Rha, +7 authors, Wei Peng Yong.
BMC Cancer, 2018 Mar 29; 18(1). PMID: 29587677    Free PMC article.
Harnessing and Optimizing the Interplay between Immunotherapy and Radiotherapy to Improve Survival Outcomes.
Kalpana Mujoo, Clayton R Hunt, +5 authors, Tej K Pandita.
Mol Cancer Res, 2018 Mar 30; 16(8). PMID: 29592896    Free PMC article.
Review.
Immunotherapy combination strategies (non-chemotherapy) in non-small cell lung cancer.
Sandrine Niyongere, Andreas Saltos, Jhanelle E Gray.
J Thorac Dis, 2018 Mar 30; 10(Suppl 3). PMID: 29593889    Free PMC article.
Review.
Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.
Tathiane M Malta, Artem Sokolov, +21 authors, Maciej Wiznerowicz.
Cell, 2018 Apr 07; 173(2). PMID: 29625051    Free PMC article.
Highly Cited.
Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy.
Tina Cascone, Jodi A McKenzie, +34 authors, Weiyi Peng.
Cell Metab, 2018 Apr 10; 27(5). PMID: 29628419    Free PMC article.
Highly Cited.
Immune Response against ALK in Children with ALK-Positive Anaplastic Large Cell Lymphoma.
Serena Stadler, Vijay Kumar Singh, +2 authors, Wilhelm Woessmann.
Cancers (Basel), 2018 Apr 13; 10(4). PMID: 29642597    Free PMC article.
Review.
The IDH1 Mutation-Induced Oncometabolite, 2-Hydroxyglutarate, May Affect DNA Methylation and Expression of PD-L1 in Gliomas.
Luyan Mu, Yu Long, +12 authors, Jianping Huang.
Front Mol Neurosci, 2018 Apr 13; 11. PMID: 29643764    Free PMC article.
In Vivo Antitumor Effects of MK615 Led by PD-L1 Downregulation.
Masashi Yanaki, Masayuki Kobayashi, +2 authors, Makoto Ozaki.
Integr Cancer Ther, 2018 Apr 19; 17(3). PMID: 29665734    Free PMC article.
Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade.
Victoria Klepsch, Natascha Hermann-Kleiter, +12 authors, Gottfried Baier.
Nat Commun, 2018 Apr 20; 9(1). PMID: 29670099    Free PMC article.
A Network Meta-analysis Comparing the Efficacy and Safety of Anti-PD-1 with Anti-PD-L1 in Non-small Cell Lung Cancer.
Wei You, Mei Liu, +5 authors, Hao Peng.
J Cancer, 2018 Apr 21; 9(7). PMID: 29675101    Free PMC article.
Immune Escape Mechanisms and Future Prospects for Immunotherapy in Neuroblastoma.
Thitinee Vanichapol, Somchai Chutipongtanate, Usanarat Anurathapan, Suradej Hongeng.
Biomed Res Int, 2018 Apr 24; 2018. PMID: 29682521    Free PMC article.
Review.
Differential Expression Patterns of Eph Receptors and Ephrin Ligands in Human Cancers.
Chung-Ting Jimmy Kou, Raj P Kandpal.
Biomed Res Int, 2018 Apr 24; 2018. PMID: 29682554    Free PMC article.
Review.
Exosomes and Immune Response in Cancer: Friends or Foes?
Francisco M Barros, Fatima Carneiro, Jose C Machado, Sónia A Melo.
Front Immunol, 2018 Apr 27; 9. PMID: 29696022    Free PMC article.
Highly Cited. Review.
The opposing roles of CD4+ T cells in anti-tumour immunity.
Tomasz Ahrends, Jannie Borst.
Immunology, 2018 Apr 28;. PMID: 29700809    Free PMC article.
Review.
Integrative Pharmacology: Advancing Development of Effective Immunotherapies.
Mohammad Tabrizi, Daping Zhang, Vaishnavi Ganti, Glareh Azadi.
AAPS J, 2018 Apr 29; 20(4). PMID: 29704129
Review.
Development of a primary melanoma in situ within a full-thickness skin graft overlying a free muscle flap: a case report.
Robert J Dabek, Nemanja Baletic, +4 authors, Branko Bojovic.
Case Reports Plast Surg Hand Surg, 2018 May 01; 5(1). PMID: 29707609    Free PMC article.
Cancer CRISPR Screens In Vivo.
Ryan D Chow, Sidi Chen.
Trends Cancer, 2018 May 02; 4(5). PMID: 29709259    Free PMC article.
Review.
Checkpoint Inhibitors in the Treatment of Breast Cancer.
Tomas G Lyons, Maura N Dickler, Elizabeth E Comen.
Curr Oncol Rep, 2018 May 02; 20(7). PMID: 29713831
Review.
Cancer growth and metastasis as a metaphor of Go gaming: An Ising model approach.
Didier Barradas-Bautista, Matias Alvarado-Mentado, Mark Agostino, Germinal Cocho.
PLoS One, 2018 May 03; 13(5). PMID: 29718932    Free PMC article.
Platelet Metabolism and Other Targeted Drugs; Potential Impact on Immunotherapy.
Preeti Kanikarla-Marie, Michael Lam, +3 authors, David G Menter.
Front Oncol, 2018 May 08; 8. PMID: 29732316    Free PMC article.
Review.
Immunotherapy for pulmonary squamous cell carcinoma and colon carcinoma with pembrolizumab: A case report.
Yoshihiro Nozawa, Yuka Oka, Jun Oosugi, Shinichi Takemura.
Medicine (Baltimore), 2018 May 10; 97(19). PMID: 29742733    Free PMC article.
Anticalin® Proteins as Therapeutic Agents in Human Diseases.
Christine Rothe, Arne Skerra.
BioDrugs, 2018 May 12; 32(3). PMID: 29748739    Free PMC article.
Review.
Notch-effector CSL promotes squamous cell carcinoma by repressing histone demethylase KDM6B.
Dania Al Labban, Seung-Hee Jo, +4 authors, G Paolo Dotto.
J Clin Invest, 2018 May 15; 128(6). PMID: 29757189    Free PMC article.
A Convergence-Based Framework for Cancer Drug Resistance.
David J Konieczkowski, Cory M Johannessen, Levi A Garraway.
Cancer Cell, 2018 May 16; 33(5). PMID: 29763622    Free PMC article.
Highly Cited. Review.
NY-ESO-1 Based Immunotherapy of Cancer: Current Perspectives.
Remy Thomas, Ghaneya Al-Khadairi, +4 authors, Julie Decock.
Front Immunol, 2018 May 18; 9. PMID: 29770138    Free PMC article.
Highly Cited. Review.
Spleen mediates a distinct hematopoietic progenitor response supporting tumor-promoting myelopoiesis.
Chong Wu, Huiheng Ning, +12 authors, Limin Zheng.
J Clin Invest, 2018 May 18; 128(8). PMID: 29771686    Free PMC article.
Macrophage-Derived Granulin Drives Resistance to Immune Checkpoint Inhibition in Metastatic Pancreatic Cancer.
Valeria Quaranta, Carolyn Rainer, +10 authors, Michael C Schmid.
Cancer Res, 2018 May 24; 78(15). PMID: 29789416    Free PMC article.
Highly Cited.
Quantitative translational modeling to facilitate preclinical to clinical efficacy & toxicity translation in oncology.
Andy Zx Zhu.
Future Sci OA, 2018 May 26; 4(5). PMID: 29796306    Free PMC article.
Review.
In Situ Vaccination with Cowpea vs Tobacco Mosaic Virus against Melanoma.
Abner A Murray, Chao Wang, Steven Fiering, Nicole F Steinmetz.
Mol Pharm, 2018 May 26; 15(9). PMID: 29798673    Free PMC article.
Prognostic and therapeutic value of CD103+ cells in renal cell carcinoma.
Jin Zhou, Lipeng Liu, Tuo Yang, Bingxin Lu.
Exp Ther Med, 2018 May 29; 15(6). PMID: 29805521    Free PMC article.
Immunotherapy for Gastric Cancer: Time for a Personalized Approach?
Riccardo Dolcetti, Valli De Re, Vincenzo Canzonieri.
Int J Mol Sci, 2018 May 31; 19(6). PMID: 29844297    Free PMC article.
Review.
Pharmacologic inhibition of protein phosphatase-2A achieves durable immune-mediated antitumor activity when combined with PD-1 blockade.
Winson S Ho, Herui Wang, +8 authors, Zhengping Zhuang.
Nat Commun, 2018 May 31; 9(1). PMID: 29844427    Free PMC article.
Immune therapies in pancreatic ductal adenocarcinoma: Where are we now?
Marc Hilmi, Laurent Bartholin, Cindy Neuzillet.
World J Gastroenterol, 2018 Jun 02; 24(20). PMID: 29853732    Free PMC article.
Highly Cited. Review.
CNS cancer immunity cycle and strategies to target this for glioblastoma.
Malaka Ameratunga, Niamh Coleman, +2 authors, Juanita Lopez.
Oncotarget, 2018 Jun 02; 9(32). PMID: 29854316    Free PMC article.
Review.
Role of tumor microenvironment in ovarian cancer pathobiology.
Alia Ghoneum, Hesham Afify, +2 authors, Neveen Said.
Oncotarget, 2018 Jun 02; 9(32). PMID: 29854318    Free PMC article.
Review.
The combined presence of CD20 + B cells and PD-L1 + tumor-infiltrating lymphocytes in inflammatory breast cancer is prognostic of improved patient outcome.
H Arias-Pulido, A Cimino-Mathews, +8 authors, S Fiering.
Breast Cancer Res Treat, 2018 Jun 03; 171(2). PMID: 29858752    Free PMC article.
Implementation of immunotherapy in the treatment of advanced non-small cell lung cancer (NSCLC).
Anna Tsiara, Michalis Liontos, +3 authors, Meletios-Athanasios Dimopoulos.
Ann Transl Med, 2018 Jun 05; 6(8). PMID: 29862233    Free PMC article.
Review.
Combined Rho-kinase inhibition and immunogenic cell death triggers and propagates immunity against cancer.
Gi-Hoon Nam, Eun Jung Lee, +10 authors, In-San Kim.
Nat Commun, 2018 Jun 06; 9(1). PMID: 29867097    Free PMC article.
PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer.
Magalie Dosset, Thaiz Rivera Vargas, +13 authors, Lionel Apetoh.
Oncoimmunology, 2018 Jun 07; 7(6). PMID: 29872568    Free PMC article.
Highly Cited.
Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy.
David Gyori, Ee Lyn Lim, +6 authors, Phillip T Hawkins.
JCI Insight, 2018 Jun 08; 3(11). PMID: 29875321    Free PMC article.
Blockade of MIF-CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma.
Carlos R Figueiredo, Ricardo A Azevedo, +9 authors, Ainhoa Mielgo.
Front Immunol, 2018 Jun 08; 9. PMID: 29875777    Free PMC article.
Tumor Regression and Cure Depends on Sustained Th1 Responses.
Min Dai, Ingegerd Hellstrom, +2 authors, Karl Erik Hellstrom.
J Immunother, 2018 Jun 19; 41(8). PMID: 29912725    Free PMC article.
Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells.
Themis Alissafi, Aikaterini Hatzioannou, +8 authors, Panayotis Verginis.
J Clin Invest, 2018 Jun 20; 128(9). PMID: 29920188    Free PMC article.
Integrating Radiosensitivity and Immune Gene Signatures for Predicting Benefit of Radiotherapy in Breast Cancer.
Yi Cui, Bailiang Li, +2 authors, Ruijiang Li.
Clin Cancer Res, 2018 Jun 21; 24(19). PMID: 29921729    Free PMC article.
Construction of an anti-programmed death-ligand 1 chimeric antigen receptor and determination of its antitumor function with transduced cells.
Jiasen Xie, Zishan Zhou, Shunchang Jiao, Xiaokun Li.
Oncol Lett, 2018 Jun 22; 16(1). PMID: 29928397    Free PMC article.
Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA).
Patrick Danaher, Sarah Warren, +6 authors, Alessandra Cesano.
J Immunother Cancer, 2018 Jun 23; 6(1). PMID: 29929551    Free PMC article.
Highly Cited.
Role of Immune Checkpoint Inhibitors in Advanced or Recurrent Endometrial Cancer.
Ena Arora, Muhammad Masab, +3 authors, Claudia Dourado.
Cureus, 2018 Jun 27; 10(4). PMID: 29942724    Free PMC article.
Review.
Fusogenic Viruses in Oncolytic Immunotherapy.
Teresa Krabbe, Jennifer Altomonte.
Cancers (Basel), 2018 Jun 29; 10(7). PMID: 29949934    Free PMC article.
Review.
Lung cancer, elderly and immune checkpoint inhibitors.
Francesca Casaluce, Assunta Sgambato, +2 authors, Cesare Gridelli.
J Thorac Dis, 2018 Jun 29; 10(Suppl 13). PMID: 29951299    Free PMC article.
Review.
Shining light on advanced NSCLC in 2017: combining immune checkpoint inhibitors.
Meng Qiao, Tao Jiang, Caicun Zhou.
J Thorac Dis, 2018 Jun 29; 10(Suppl 13). PMID: 29951304    Free PMC article.
Review.
Glioblastoma Stem-Like Cells Are More Susceptible Than Differentiated Cells to Natural Killer Cell Lysis Mediated Through Killer Immunoglobulin-Like Receptors-Human Leukocyte Antigen Ligand Mismatch and Activation Receptor-Ligand Interactions.
Heleen Neeltje Haspels, Mohummad Aminur Rahman, +2 authors, Martha Chekenya.
Front Immunol, 2018 Jul 04; 9. PMID: 29967607    Free PMC article.
Immune cell profiling in the age of immune checkpoint inhibitors: implications for biomarker discovery and understanding of resistance mechanisms.
Su Yin Lim, Helen Rizos.
Mamm Genome, 2018 Jul 04; 29(11-12). PMID: 29968076    Free PMC article.
Review.
Tumor matrix remodeling and novel immunotherapies: the promise of matrix-derived immune biomarkers.
Muhammad Umair Mushtaq, Athanasios Papadas, +4 authors, Fotis Asimakopoulos.
J Immunother Cancer, 2018 Jul 05; 6(1). PMID: 29970158    Free PMC article.
Review.
PD-L1 Nanobody Competitively Inhibits the Formation of the PD-1/PD-L1 Complex: Comparative Molecular Dynamics Simulations.
Xin Sun, Xiao Yan, +10 authors, Jianping Hu.
Int J Mol Sci, 2018 Jul 11; 19(7). PMID: 29986511    Free PMC article.
Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells.
Yunlong Zhao, Devin L Harrison, +3 authors, Enfu Hui.
Cell Rep, 2018 Jul 12; 24(2). PMID: 29996099    Free PMC article.
Onconeural antigen spreading in paraneoplastic neurological disease due to small cell lung cancer.
Andre Dik, Christine Strippel, +7 authors, Nico Melzer.
Oxf Med Case Reports, 2018 Jul 14; 2018(7). PMID: 30002861    Free PMC article.
Hide or defend, the two strategies of lymphoma immune evasion: potential implications for immunotherapy.
Marie de Charette, Roch Houot.
Haematologica, 2018 Jul 15; 103(8). PMID: 30006449    Free PMC article.
Review.
TCRs are randomly distributed on the plasma membrane of resting antigen-experienced T cells.
Benedikt Rossboth, Andreas M Arnold, +6 authors, Gerhard J Schütz.
Nat Immunol, 2018 Jul 18; 19(8). PMID: 30013143    Free PMC article.
Improved Induction of Anti-Melanoma T Cells by Adenovirus-5/3 Fiber Modification to Target Human DCs.
Dafni Chondronasiou, Tracy-Jane T H D Eisden, +7 authors, Rieneke van de Ven.
Vaccines (Basel), 2018 Jul 20; 6(3). PMID: 30022005    Free PMC article.
The Potential of In Vivo Imaging for Optimization of Molecular and Cellular Anti-cancer Immunotherapies.
Gilbert O Fruhwirth, Manfred Kneilling, +3 authors, Erik H J G Aarntzen.
Mol Imaging Biol, 2018 Jul 22; 20(5). PMID: 30030697    Free PMC article.
Review.
The evolving immunotherapeutic landscape in advanced oesophagogastric cancer.
Michael Flynn, Kate Young, David Cunningham, Naureen Starling.
Ther Adv Med Oncol, 2018 Jul 24; 10. PMID: 30034550    Free PMC article.
Review.
New Directions in the Study and Treatment of Metastatic Cancer.
Byunghee Yoo, Bryan C Fuchs, Zdravka Medarova.
Front Oncol, 2018 Jul 26; 8. PMID: 30042926    Free PMC article.
Review.
Role of Tissue-Resident Memory in Intra-Tumor Heterogeneity and Response to Immune Checkpoint Blockade.
Kavita M Dhodapkar.
Front Immunol, 2018 Aug 01; 9. PMID: 30061902    Free PMC article.
Review.
Activation of central/effector memory T cells and T-helper 1 polarization in malignant melanoma patients treated with anti-programmed death-1 antibody.
Kyoko Yamaguchi, Koji Mishima, +12 authors, Eishi Baba.
Cancer Sci, 2018 Aug 02; 109(10). PMID: 30066977    Free PMC article.
Sno-derived RNAs are prevalent molecular markers of cancer immunity.
Ryan D Chow, Sidi Chen.
Oncogene, 2018 Aug 04; 37(50). PMID: 30072739    Free PMC article.
White paper on microbial anti-cancer therapy and prevention.
Neil S Forbes, Robert S Coffin, +20 authors, Grant McFadden.
J Immunother Cancer, 2018 Aug 08; 6(1). PMID: 30081947    Free PMC article.
Review.
Next Generation Cancer Vaccines-Make It Personal!
Angelika Terbuch, Juanita Lopez.
Vaccines (Basel), 2018 Aug 12; 6(3). PMID: 30096953    Free PMC article.
Review.
Immune Checkpoint-Mediated Interactions Between Cancer and Immune Cells in Prostate Adenocarcinoma and Melanoma.
Angela Rita Elia, Sara Caputo, Matteo Bellone.
Front Immunol, 2018 Aug 16; 9. PMID: 30108594    Free PMC article.
Review.
Circulating T Cell Subpopulations Correlate With Immune Responses at the Tumor Site and Clinical Response to PD1 Inhibition in Non-Small Cell Lung Cancer.
Nataly Manjarrez-Orduño, Laurence C Menard, +15 authors, Steven G Nadler.
Front Immunol, 2018 Aug 21; 9. PMID: 30123214    Free PMC article.
Neutrophil-to-lymphocyte ratio after four weeks of nivolumab administration as a predictive marker in patients with pretreated non-small-cell lung cancer.
Takayuki Takeda, Mayumi Takeuchi, Masahiko Saitoh, Sorou Takeda.
Thorac Cancer, 2018 Aug 21; 9(10). PMID: 30126063    Free PMC article.
ALX148 blocks CD47 and enhances innate and adaptive antitumor immunity with a favorable safety profile.
Steven E Kauder, Tracy C Kuo, +9 authors, Hong I Wan.
PLoS One, 2018 Aug 23; 13(8). PMID: 30133535    Free PMC article.
Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes.
Lien Van Hoecke, Sandra Van Lint, +6 authors, Xavier Saelens.
Nat Commun, 2018 Aug 26; 9(1). PMID: 30143632    Free PMC article.
CEA: Combination-based gene set functional enrichment analysis.
Duanchen Sun, Yinliang Liu, Xiang-Sun Zhang, Ling-Yun Wu.
Sci Rep, 2018 Sep 01; 8(1). PMID: 30166636    Free PMC article.
Prognostic significance of tumor immune microenvironment and immunotherapy: Novel insights and future perspectives in gastric cancer.
Daniela Cornelia Lazăr, Mihaela Flavia Avram, +3 authors, Adrian Goldiș.
World J Gastroenterol, 2018 Sep 01; 24(32). PMID: 30166856    Free PMC article.
Highly Cited. Review.
Magnetic resonance imaging and molecular features associated with tumor-infiltrating lymphocytes in breast cancer.
Jia Wu, Xuejie Li, +4 authors, Ruijiang Li.
Breast Cancer Res, 2018 Sep 05; 20(1). PMID: 30176944    Free PMC article.
Topography of cancer-associated immune cells in human solid tumors.
Jakob Nikolas Kather, Meggy Suarez-Carmona, +17 authors, Niels Halama.
Elife, 2018 Sep 05; 7. PMID: 30179157    Free PMC article.
Highly Cited.
Treg Destabilization and Reprogramming: Implications for Cancer Immunotherapy.
David H Munn, Madhav D Sharma, Theodore S Johnson.
Cancer Res, 2018 Sep 06; 78(18). PMID: 30181177    Free PMC article.
Review.
Targeting immune checkpoints in melanoma: an update.
Rodrigo R Munhoz, Alejandro Falcón González, Vanessa A Reed, Michael A Postow.
Melanoma Manag, 2015 Nov 01; 2(4). PMID: 30190862    Free PMC article.
Review.
The role of tumor microenvironment in melanoma therapy resistance.
Rajasekharan Somasundaram, Meenhard Herlyn, Stephan N Wagner.
Melanoma Manag, 2016 Mar 01; 3(1). PMID: 30190870    Free PMC article.
Review.
Dendritic cell vaccines for melanoma: past, present and future.
Robert O Dillman, Gabriel I Nistor, Andrew N Cornforth.
Melanoma Manag, 2016 Dec 01; 3(4). PMID: 30190899    Free PMC article.
Review.
An update on the relevance of vaccine research for the treatment of metastatic melanoma.
Robert O Dillman.
Melanoma Manag, 2018 Sep 08; 4(4). PMID: 30190926    Free PMC article.
Review.
Regulation of Ovarian Cancer Prognosis by Immune Cells in the Tumor Microenvironment.
Maureen L Drakes, Patrick J Stiff.
Cancers (Basel), 2018 Sep 12; 10(9). PMID: 30200478    Free PMC article.
Review.
Perspectives for cancer immunotherapy mediated by p19Arf plus interferon-beta gene transfer.
Bryan E Strauss, Gissele Rolemberg Oliveira Silva, +4 authors, Samir Andrade Mendonça.
Clinics (Sao Paulo), 2018 Sep 13; 73(suppl 1). PMID: 30208166    Free PMC article.
Review.
Expression of IL-23R and IL-17 and the pathology and prognosis of urinary bladder carcinoma.
Jian Liu, Lei Wang, Tongqing Wang, Jizheng Wang.
Oncol Lett, 2018 Sep 15; 16(4). PMID: 30214568    Free PMC article.
[Molecular predictors in immune oncology].
W Weichert.
Pathologe, 2018 Sep 15; 39(6). PMID: 30215118
Review.
New strategies in immunotherapy for lung cancer: beyond PD-1/PD-L1.
Nicolas Villanueva, Lyudmila Bazhenova.
Ther Adv Respir Dis, 2018 Sep 15; 12. PMID: 30215300    Free PMC article.
Review.
Mechanism and Management of Cancer Chemotherapy-Induced Atherosclerosis.
Mikio Mukai, Keiko Komori, Toru Oka.
J Atheroscler Thromb, 2018 Sep 19; 25(10). PMID: 30224607    Free PMC article.
Review.
Duokines: a novel class of dual-acting co-stimulatory molecules acting in cis or trans.
Sina Fellermeier-Kopf, Friederike Gieseke, +3 authors, Roland E Kontermann.
Oncoimmunology, 2018 Sep 20; 7(9). PMID: 30228940    Free PMC article.
Transforming Growth Factor-β-Induced Cell Plasticity in Liver Fibrosis and Hepatocarcinogenesis.
Isabel Fabregat, Daniel Caballero-Díaz.
Front Oncol, 2018 Sep 27; 8. PMID: 30250825    Free PMC article.
Highly Cited. Review.
A neoepitope derived from a novel human germline APC gene mutation in familial adenomatous polyposis shows selective immunogenicity.
Snigdha Majumder, Rakshit Shah, +14 authors, Arati Khanna-Gupta.
PLoS One, 2018 Sep 27; 13(9). PMID: 30256815    Free PMC article.
ICAM-1-LFA-1 Dependent CD8+ T-Lymphocyte Aggregation in Tumor Tissue Prevents Recirculation to Draining Lymph Nodes.
Alba Yanguas, Saray Garasa, +3 authors, Ana Rouzaut.
Front Immunol, 2018 Sep 28; 9. PMID: 30258446    Free PMC article.
Recent advances in extracellular vesicles enriched with non-coding RNAs related to cancers.
Song Yang, Xi Li.
Genes Dis, 2018 Sep 28; 5(1). PMID: 30258933    Free PMC article.
Review.
RNAi-Mediated β-Catenin Inhibition Promotes T Cell Infiltration and Antitumor Activity in Combination with Immune Checkpoint Blockade.
Shanthi Ganesh, Xue Shui, +4 authors, Marc T Abrams.
Mol Ther, 2018 Oct 03; 26(11). PMID: 30274786    Free PMC article.
Ruthenium pyridyl thiocyanate complex increased the production of pro-inflammatory TNFα and IL1β cytokines by the LPS stimulated mammalian macrophages in vitro.
Furkan Ayaz.
Mol Biol Rep, 2018 Oct 05; 45(6). PMID: 30284682
Epigenetic treatment of multiple myeloma mediates tumor intrinsic and extrinsic immunomodulatory effects.
Lien De Beck, Sarah Melhaoui, +5 authors, Ken Maes.
Oncoimmunology, 2018 Oct 06; 7(10). PMID: 30288346    Free PMC article.
Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1).
Marcin Kowanetz, Wei Zou, +27 authors, Priti S Hegde.
Proc Natl Acad Sci U S A, 2018 Oct 10; 115(43). PMID: 30297397    Free PMC article.
Highly Cited.
Reinforce the antitumor activity of CD8+ T cells via glutamine restriction.
Shogo Nabe, Takeshi Yamada, +7 authors, Masakatsu Yamashita.
Cancer Sci, 2018 Oct 12; 109(12). PMID: 30302856    Free PMC article.
Pharmacometric Applications and Challenges in the Development of Therapeutic Antibodies in Immuno-Oncology.
Lei Diao, Bernd Meibohm.
Curr Pharmacol Rep, 2018 Oct 16; 4(4). PMID: 30319936    Free PMC article.
Multimodal detection of PD-L1: reasonable biomarkers for immune checkpoint inhibitor.
Qiao Yang, Zihan Xu, +3 authors, Jianguo Sun.
Am J Cancer Res, 2018 Oct 17; 8(9). PMID: 30323963    Free PMC article.
Review.
Predictive impact of absolute lymphocyte counts for progression-free survival in human epidermal growth factor receptor 2-positive advanced breast cancer treated with pertuzumab and trastuzumab plus eribulin or nab-paclitaxel.
Kazuhiro Araki, Yoshinori Ito, +9 authors, Yasuo Miyoshi.
BMC Cancer, 2018 Oct 18; 18(1). PMID: 30326862    Free PMC article.
Dendritic Cell Cancer Therapy: Vaccinating the Right Patient at the Right Time.
Wouter W van Willigen, Martine Bloemendal, +3 authors, Kalijn F Bol.
Front Immunol, 2018 Oct 18; 9. PMID: 30327656    Free PMC article.
Highly Cited. Review.
[Immunological foundations of modern (tumor) immunotherapy].
T Bopp, H Schild.
Pathologe, 2018 Oct 18; 39(6). PMID: 30327859
Review.
Multi-Omics Profiling of the Tumor Microenvironment: Paving the Way to Precision Immuno-Oncology.
Francesca Finotello, Federica Eduati.
Front Oncol, 2018 Oct 23; 8. PMID: 30345255    Free PMC article.
Review.
Anti-PD-1/PD-L1 Antibody Therapy for Pretreated Advanced or Metastatic Nonsmall Cell Lung Carcinomas and the Correlation between PD-L1 Expression and Treatment Effectiveness: An Update Meta-Analysis of Randomized Clinical Trials.
Qiuling Zhao, Ruixiang Xie, +2 authors, Xiuhua Weng.
Biomed Res Int, 2018 Oct 23; 2018. PMID: 30345301    Free PMC article.
Systematic Review.
[Prognostic significance of immune cell infiltrates in tumor pathology].
D-C Wagner, W Roth.
Pathologe, 2018 Oct 24; 39(6). PMID: 30350175
Review.
Immune regulation of metastasis: mechanistic insights and therapeutic opportunities.
Olga S Blomberg, Lorenzo Spagnuolo, Karin E de Visser.
Dis Model Mech, 2018 Oct 26; 11(10). PMID: 30355585    Free PMC article.
Review.
Predicting T cell recognition of MHC class I restricted neoepitopes.
Zeynep Koşaloğlu-Yalçın, Manasa Lanka, +8 authors, Bjoern Peters.
Oncoimmunology, 2018 Nov 01; 7(11). PMID: 30377561    Free PMC article.
HIV control: Is getting there the same as staying there?
Philip Goulder, Steven G Deeks.
PLoS Pathog, 2018 Nov 02; 14(11). PMID: 30383857    Free PMC article.
Review.
Sitravatinib potentiates immune checkpoint blockade in refractory cancer models.
Wenting Du, Huocong Huang, Noah Sorrelle, Rolf A Brekken.
JCI Insight, 2018 Nov 06; 3(21). PMID: 30385724    Free PMC article.
The Role of PD-1 Checkpoint Inhibition in Gynecologic Malignancies.
Christine Garcia, Kari L Ring.
Curr Treat Options Oncol, 2018 Nov 07; 19(12). PMID: 30397772
Review.
The Roles of Autophagy in Cancer.
Chul Won Yun, Sang Hun Lee.
Int J Mol Sci, 2018 Nov 08; 19(11). PMID: 30400561    Free PMC article.
Highly Cited. Review.
Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2.
Zuqiang Liu, Yan Ge, +5 authors, David L Bartlett.
Nat Commun, 2018 Nov 10; 9(1). PMID: 30410056    Free PMC article.
Engineering CAR-T Cells for Improved Function Against Solid Tumors.
Michael A Morgan, Axel Schambach.
Front Immunol, 2018 Nov 14; 9. PMID: 30420856    Free PMC article.
Review.
Combination Immune Checkpoint Blockade Strategies to Maximize Immune Response in Gynecological Cancers.
Ying L Liu, Dmitriy Zamarin.
Curr Oncol Rep, 2018 Nov 14; 20(12). PMID: 30421009    Free PMC article.
Review.
Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia.
Lelinh Duong, Hannah G Radley-Crabb, +6 authors, Connie Jackaman.
Front Genet, 2018 Nov 22; 9. PMID: 30459812    Free PMC article.
The role of neoantigen in immune checkpoint blockade therapy.
Ming Yi, Shuang Qin, +3 authors, Kongming Wu.
Exp Hematol Oncol, 2018 Nov 27; 7. PMID: 30473928    Free PMC article.
Highly Cited. Review.
Transformation of Old Concepts for a New Era of Cancer Immunotherapy: Cytokine Therapy and Cancer Vaccines as Combination Partners of PD1/PD-L1 Inhibitors.
Romualdo Barroso-Sousa, Patrick A Ott.
Curr Oncol Rep, 2018 Dec 01; 21(1). PMID: 30498900
Review.
Clinical utility of tumor mutational burden in patients with non-small cell lung cancer treated with immunotherapy.
Lizza E Hendriks, Etienne Rouleau, Benjamin Besse.
Transl Lung Cancer Res, 2018 Dec 07; 7(6). PMID: 30505709    Free PMC article.
Review.
Antigen-specificity and DTIC before peptide-vaccination differently shape immune-checkpoint expression pattern, anti-tumor functionality and TCR repertoire in melanoma patients.
Belinda Palermo, Ornella Franzese, +9 authors, Paola Nisticò.
Oncoimmunology, 2018 Dec 14; 7(12). PMID: 30524882    Free PMC article.
Adoptive cell therapy with tumor-infiltrating lymphocytes in patients with metastatic ovarian cancer: a pilot study.
Magnus Pedersen, Marie Christine Wulff Westergaard, +14 authors, Inge Marie Svane.
Oncoimmunology, 2018 Dec 14; 7(12). PMID: 30524900    Free PMC article.
Genetic associations of T cell cancer immune response with tumor aggressiveness in localized prostate cancer patients and disease reclassification in an active surveillance cohort.
Qinchuan Wang, Justin R Gregg, +7 authors, Xifeng Wu.
Oncoimmunology, 2018 Dec 14; 8(1). PMID: 30546938    Free PMC article.
Priming anti-tumor immunity by radiotherapy: Dying tumor cell-derived DAMPs trigger endothelial cell activation and recruitment of myeloid cells.
Julia Krombach, Roman Hennel, +12 authors, Kirsten Lauber.
Oncoimmunology, 2018 Dec 14; 8(1). PMID: 30546963    Free PMC article.
Therapeutic vaccination using minimal HPV16 epitopes in a novel MHC-humanized murine HPV tumor model.
Sebastian Kruse, Marleen Büchler, +9 authors, Angelika B Riemer.
Oncoimmunology, 2018 Dec 14; 8(1). PMID: 30546964    Free PMC article.
Integrating clinical, molecular, proteomic and histopathological data within the tissue context: tissunomics.
Santiago Ramón Y Cajal, Stefan Hümmer, +5 authors, Javier Hernandez-Losa.
Histopathology, 2019 Jan 23; 75(1). PMID: 30667539    Free PMC article.
Review.
The Impact of Cisplatin- or Non-Cisplatin-Containing Chemotherapy on Long-Term and Conditional Survival of Patients with Advanced Urinary Tract Cancer.
Aristotelis Bamias, Kimon Tzannis, +19 authors, Matthew D Galsky.
Oncologist, 2019 Apr 03; 24(10). PMID: 30936379    Free PMC article.
Unlocking the therapeutic potential of primary tumor-draining lymph nodes.
Jossie Rotman, Bas D Koster, +2 authors, Tanja D de Gruijl.
Cancer Immunol Immunother, 2019 Apr 05; 68(10). PMID: 30944963    Free PMC article.
Review.
The current state of molecular testing in the treatment of patients with solid tumors, 2019.
Wafik S El-Deiry, Richard M Goldberg, +10 authors, John L Marshall.
CA Cancer J Clin, 2019 May 23; 69(4). PMID: 31116423    Free PMC article.
Highly Cited. Review.
Immunometabolism: A new target for improving cancer immunotherapy.
Chunqing Guo, Shixian Chen, +5 authors, Xiang-Yang Wang.
Adv Cancer Res, 2019 Jun 17; 143. PMID: 31202359    Free PMC article.
Review.
A tumor-targeting nanomedicine carrying the p53 gene crosses the blood-brain barrier and enhances anti-PD-1 immunotherapy in mouse models of glioblastoma.
Sang-Soo Kim, Joe B Harford, +3 authors, Esther H Chang.
Int J Cancer, 2019 Jun 27; 145(9). PMID: 31241175    Free PMC article.
Multicentric analytical comparability study of programmed death-ligand 1 expression on tumor-infiltrating immune cells and tumor cells in urothelial bladder cancer using four clinically developed immunohistochemistry assays.
Kristina Schwamborn, Johannes U Ammann, +9 authors, Wilko Weichert.
Virchows Arch, 2019 Jul 04; 475(5). PMID: 31267201    Free PMC article.
A Platform for Extracellular Interactome Discovery Identifies Novel Functional Binding Partners for the Immune Receptors B7-H3/CD276 and PVR/CD155.
Bushra Husain, Sree R Ramani, +13 authors, Nadia Martinez-Martin.
Mol Cell Proteomics, 2019 Jul 17; 18(11). PMID: 31308249    Free PMC article.
Inhaled Submicron Particle Paclitaxel (NanoPac) Induces Tumor Regression and Immune Cell Infiltration in an Orthotopic Athymic Nude Rat Model of Non-Small Cell Lung Cancer.
James Verco, William Johnston, +7 authors, Gere diZerega.
J Aerosol Med Pulm Drug Deliv, 2019 Jul 28; 32(5). PMID: 31347939    Free PMC article.
Subsequent therapies and survival after immunotherapy in recurrent ovarian cancer.
Ying L Liu, Qin Zhou, +6 authors, Dmitriy Zamarin.
Gynecol Oncol, 2019 Aug 20; 155(1). PMID: 31421916    Free PMC article.
Glycan-Modified Apoptotic Melanoma-Derived Extracellular Vesicles as Antigen Source for Anti-Tumor Vaccination
Sophie K Horrevorts, Dorian A Stolk, +12 authors, Yvette van Kooyk.
Cancers (Basel), 2019 Aug 31; 11(9). PMID: 31466401    Free PMC article.
Immunotherapy with Monoclonal Antibodies in Lung Cancer of Mice: Oxidative Stress and Other Biological Events.
Jun Tang, Daniel Ramis-Cabrer, Xuejie Wang, Esther Barreiro.
Cancers (Basel), 2019 Sep 07; 11(9). PMID: 31487876    Free PMC article.
The application of nanotechnology in enhancing immunotherapy for cancer treatment: current effects and perspective.
Yongjiang Li, Ciceron Ayala-Orozco, Pradipta Ranjan Rauta, Sunil Krishnan.
Nanoscale, 2019 Sep 19; 11(37). PMID: 31531445    Free PMC article.
Review.
Alternative dosing regimens for atezolizumab: an example of model-informed drug development in the postmarketing setting.
Kari M Morrissey, Mathilde Marchand, +8 authors, René Bruno.
Cancer Chemother Pharmacol, 2019 Sep 23; 84(6). PMID: 31542806    Free PMC article.
Bispecific T-Cell Redirection versus Chimeric Antigen Receptor (CAR)-T Cells as Approaches to Kill Cancer Cells.
William R Strohl, Michael Naso.
Antibodies (Basel), 2019 Sep 24; 8(3). PMID: 31544847    Free PMC article.
Review.
In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma.
Lupeng Ye, Jonathan J Park, +9 authors, Sidi Chen.
Nat Biotechnol, 2019 Sep 25; 37(11). PMID: 31548728    Free PMC article.
Tumour Microenvironment and Immune Evasion in EGFR Addicted NSCLC: Hurdles and Possibilities.
Antonio Santaniello, Fabiana Napolitano, +5 authors, Roberto Bianco.
Cancers (Basel), 2019 Sep 27; 11(10). PMID: 31554160    Free PMC article.
Review.
Interaction of Immune Cells and Tumor Cells in Gold Nanorod-Gelatin Composite Porous Scaffolds.
Xiuhui Wang, Naoki Kawazoe, Guoping Chen.
Nanomaterials (Basel), 2019 Sep 27; 9(10). PMID: 31554195    Free PMC article.
Current applications and future prospects of nanotechnology in cancer immunotherapy.
Sen Yan, Peng Zhao, Tingting Yu, Ning Gu.
Cancer Biol Med, 2019 Oct 01; 16(3). PMID: 31565479    Free PMC article.
Genome-Wide Methylation Profiling in Canine Mammary Tumor Reveals miRNA Candidates Associated with Human Breast Cancer.
Su-Jin Jeong, Kang-Hoon Lee, A-Reum Nam, Je-Yoel Cho.
Cancers (Basel), 2019 Oct 02; 11(10). PMID: 31569550    Free PMC article.
[Fam-] trastuzumab deruxtecan (DS-8201a)-induced antitumor immunity is facilitated by the anti-CTLA-4 antibody in a mouse model.
Tomomi Nakayama Iwata, Kiyoshi Sugihara, Teiji Wada, Toshinori Agatsuma.
PLoS One, 2019 Oct 02; 14(10). PMID: 31574081    Free PMC article.
The adequacy of tissue microarrays in the assessment of inter- and intra-tumoural heterogeneity of infiltrating lymphocyte burden in leiomyosarcoma.
A T J Lee, W Chew, +9 authors, P H Huang.
Sci Rep, 2019 Oct 12; 9(1). PMID: 31601875    Free PMC article.
Immuno-Oncology Therapy for Hepatocellular Carcinoma: Current Status and Ongoing Trials.
Masatoshi Kudo.
Liver Cancer, 2019 Oct 12; 8(4). PMID: 31602367    Free PMC article.
Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity.
Guangchuan Wang, Ryan D Chow, +12 authors, Sidi Chen.
Nat Immunol, 2019 Oct 16; 20(11). PMID: 31611701    Free PMC article.
WNT/β-Catenin Signaling Pathway Regulating T Cell-Inflammation in the Tumor Microenvironment.
Xin Li, Yanwei Xiang, +3 authors, Xisong Ke.
Front Immunol, 2019 Oct 17; 10. PMID: 31616443    Free PMC article.
Review.
Preclinical rationale and clinical efficacy of antiangiogenic therapy and immune checkpoint blockade combination therapy in urogenital tumors.
Ning Zhu, Shanshan Weng, +4 authors, Ying Yuan.
J Cancer Res Clin Oncol, 2019 Oct 17; 145(12). PMID: 31617075
Review.
NANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis.
Kotaro Saga, Jinhee Park, +4 authors, Yasufumi Kaneda.
J Exp Clin Cancer Res, 2019 Oct 18; 38(1). PMID: 31619256    Free PMC article.
Alphavirus-based hepatitis C virus therapeutic vaccines: can universal helper epitopes enhance HCV-specific cytotoxic T lymphocyte responses?
Georgia Koutsoumpli, Peng Peng Ip, +3 authors, Toos Daemen.
Ther Adv Vaccines Immunother, 2019 Oct 18; 7. PMID: 31620673    Free PMC article.
Macrophages on the Peritoneum are involved in Gastric Cancer Peritoneal Metastasis.
Hongjiang Song, Tie Wang, +4 authors, Yingwei Xue.
J Cancer, 2019 Oct 22; 10(22). PMID: 31632482    Free PMC article.
Suppression of tumor antigen presentation during aneuploid tumor evolution contributes to immune evasion.
Reshmi Tripathi, Vishnu Modur, +2 authors, Kakajan Komurov.
Oncoimmunology, 2019 Oct 28; 8(11). PMID: 31646083    Free PMC article.
Acute myeloid leukemia-induced T-cell suppression can be reversed by inhibition of the MAPK pathway.
Kaycee B Moshofsky, Hyun J Cho, +5 authors, Evan F Lind.
Blood Adv, 2019 Oct 28; 3(20). PMID: 31648326    Free PMC article.
Analysis of tumour ecological balance reveals resource-dependent adaptive strategies of ovarian cancer.
Sidra Nawaz, Nicholas A Trahearn, +4 authors, Yinyin Yuan.
EBioMedicine, 2019 Oct 28; 48. PMID: 31648981    Free PMC article.
Dendritic Cell Vaccination in Metastatic Melanoma Turns "Non-T Cell Inflamed" Into "T-Cell Inflamed" Tumors.
Jenny Bulgarelli, Marcella Tazzari, +14 authors, Massimo Guidoboni.
Front Immunol, 2019 Oct 28; 10. PMID: 31649669    Free PMC article.
Chemotherapy-Induced Tumor Cell Death at the Crossroads Between Immunogenicity and Immunotolerance: Focus on Acute Myeloid Leukemia.
Darina Ocadlikova, Mariangela Lecciso, +5 authors, Antonio Curti.
Front Oncol, 2019 Oct 28; 9. PMID: 31649875    Free PMC article.
Review.
Update Breast Cancer 2019 Part 5 - Diagnostic and Therapeutic Challenges of New, Personalised Therapies in Patients with Advanced Breast Cancer.
Manfred Welslau, Andreas D Hartkopf, +17 authors, Tanja N Fehm.
Geburtshilfe Frauenheilkd, 2019 Oct 28; 79(10). PMID: 31656319    Free PMC article.
Imaging of T-cells and their responses during anti-cancer immunotherapy.
Massis Krekorian, Gilbert O Fruhwirth, +4 authors, Erik H J G Aarntzen.
Theranostics, 2019 Oct 28; 9(25). PMID: 31656546    Free PMC article.
Review.
The dark side of immunotherapy: challenges facing the new hope in cancer treatment.
Eduard Teixidor, Joaquim Bosch-Barrera.
Ann Transl Med, 2019 Oct 28; 7(Suppl 6). PMID: 31656762    Free PMC article.
The Activity of Immune Checkpoint Inhibition in KRAS Mutated Non-small Cell Lung Cancer: A Single Centre Experience.
Javier Torralvo, Alex Friedlaender, Verane Achard, Alfredo Addeo.
Cancer Genomics Proteomics, 2019 Oct 30; 16(6). PMID: 31659111    Free PMC article.
The efficacy and safety of combination of PD-1 and CTLA-4 inhibitors: a meta-analysis.
Kongju Wu, Ming Yi, +3 authors, Kongming Wu.
Exp Hematol Oncol, 2019 Nov 02; 8. PMID: 31673481    Free PMC article.
Review.
STING: a master regulator in the cancer-immunity cycle.
Yuanyuan Zhu, Xiang An, +3 authors, Xiaobo Li.
Mol Cancer, 2019 Nov 05; 18(1). PMID: 31679519    Free PMC article.
Review.
Postablation Immune Microenvironment: Synergy between Interventional Oncology and Immuno-oncology.
DaeHee Kim, Joseph P Erinjeri.
Semin Intervent Radiol, 2019 Nov 05; 36(4). PMID: 31680725    Free PMC article.
Review.
A Sialylated-Bortezomib Prodrug Strategy Based on a Highly Expressed Selectin Target for the Treatment of Leukemia or Solid Tumors.
Mingqi Liu, Xueying Tang, +4 authors, Yanzhi Song.
Pharm Res, 2019 Nov 07; 36(12). PMID: 31686241
Recent advances and application of PD-1 blockade in sarcoma.
Wenli Zuo, Lingdi Zhao.
Onco Targets Ther, 2019 Nov 07; 12. PMID: 31692518    Free PMC article.
Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.
Jianguo Huang, Mark Chen, +9 authors, David G Kirsch.
Sci Rep, 2019 Nov 22; 9(1). PMID: 31748650    Free PMC article.
Immune System Evasion as Hallmark of Melanoma Progression: The Role of Dendritic Cells.
Marco Tucci, Anna Passarelli, +4 authors, Francesco Silvestris.
Front Oncol, 2019 Nov 22; 9. PMID: 31750245    Free PMC article.
Review.
The immune landscape of esophageal cancer.
Tu-Xiong Huang, Li Fu.
Cancer Commun (Lond), 2019 Nov 28; 39(1). PMID: 31771653    Free PMC article.
Review.
Identification of core differentially methylated genes in glioma.
Jing Xue, Hai-Xia Gao, +6 authors, Wei Zhang.
Oncol Lett, 2019 Dec 04; 18(6). PMID: 31788078    Free PMC article.
Comparative Approach to the Temporo-Spatial Organization of the Tumor Microenvironment.
Kendall L Langsten, Jong Hyuk Kim, +2 authors, Jaime F Modiano.
Front Oncol, 2019 Dec 04; 9. PMID: 31788448    Free PMC article.
Review.
Is the Combination of Immunotherapy and Radiotherapy in Non-small Cell Lung Cancer a Feasible and Effective Approach?
Mathieu Spaas, Yolande Lievens.
Front Med (Lausanne), 2019 Dec 04; 6. PMID: 31788476    Free PMC article.
Review.
Immune pressures drive the promoter hypermethylation of neoantigen genes.
Ming Yi, Bing Dong, Qian Chu, Kongming Wu.
Exp Hematol Oncol, 2019 Dec 05; 8. PMID: 31799063    Free PMC article.
Blocking TGF-β Signaling To Enhance The Efficacy Of Immune Checkpoint Inhibitor.
Xianguang Bai, Ming Yi, +2 authors, Kongming Wu.
Onco Targets Ther, 2019 Dec 07; 12. PMID: 31807028    Free PMC article.
Review.
Antiestrogens in combination with immune checkpoint inhibitors in breast cancer immunotherapy.
Diana C Márquez-Garbán, Gang Deng, +7 authors, Richard J Pietras.
J Steroid Biochem Mol Biol, 2019 Jun 22; 193. PMID: 31226312    Free PMC article.
Highlights of 2019 Protein Engineering Summit (PEGS) in Boston, USA: Advancing Antibody-Based Cancer Therapies to the Clinic.
Hong Li, You Li, +2 authors, Mitchell Ho.
Antib Ther, 2019 Dec 18; 2(4). PMID: 31844838    Free PMC article.
Proteolytic chemokine cleavage as a regulator of lymphocytic infiltration in solid tumors.
Holger Bronger, Viktor Magdolen, Peter Goettig, Tobias Dreyer.
Cancer Metastasis Rev, 2019 Sep 05; 38(3). PMID: 31482487    Free PMC article.
Review.
Allies or Enemies-The Multifaceted Role of Myeloid Cells in the Tumor Microenvironment.
Lisa Haas, Anna C Obenauf.
Front Immunol, 2019 Dec 19; 10. PMID: 31849950    Free PMC article.
Review.
Safety and Efficacy Results of a Phase I, Open-Label Study of Concurrent and Delayed Nivolumab in Combination With nab-Paclitaxel and Carboplatin in Advanced Non-small Cell Lung Cancer.
Jonathan W Goldman, David M Waterhouse, +7 authors, Karen Kelly.
Front Oncol, 2019 Dec 19; 9. PMID: 31850192    Free PMC article.
Phase Ib study of atezolizumab combined with cobimetinib in patients with solid tumors.
M D Hellmann, T-W Kim, +18 authors, J Bendell.
Ann Oncol, 2019 Mar 29; 30(7). PMID: 30918950    Free PMC article.
Hedgehog/GLI signaling in tumor immunity - new therapeutic opportunities and clinical implications.
Sandra Grund-Gröschke, Georg Stockmaier, Fritz Aberger.
Cell Commun Signal, 2019 Dec 28; 17(1). PMID: 31878932    Free PMC article.
Review.
High CD3 and ICOS and low TIM-3 expression predict favourable survival in resected oesophageal squamous cell carcinoma.
Min Hee Hong, Su-Jin Shin, +8 authors, Hye Ryun Kim.
Sci Rep, 2019 Dec 29; 9(1). PMID: 31882943    Free PMC article.
Subgroup analysis of Japanese patients in a Phase 3 study of atezolizumab in advanced triple-negative breast cancer (IMpassion130).
Hiroji Iwata, Kenichi Inoue, +6 authors, Kenji Tamura.
Jpn J Clin Oncol, 2019 Oct 16; 49(12). PMID: 31612909    Free PMC article.
Functional Cellular Anti-Tumor Mechanisms are Augmented by Genetic Proteoglycan Targeting.
Purva Gupta, Scott C Johns, +3 authors, Mark M Fuster.
Neoplasia, 2020 Jan 04; 22(2). PMID: 31896526    Free PMC article.
Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity.
Mikhail Binnewies, Adriana M Mujal, +15 authors, Matthew F Krummel.
Cell, 2019 Apr 09; 177(3). PMID: 30955881    Free PMC article.
Highly Cited.
Nucleic Acid Nanoparticles at a Crossroads of Vaccines and Immunotherapies.
Marina A Dobrovolskaia.
Molecules, 2019 Dec 22; 24(24). PMID: 31861154    Free PMC article.
Review.
Relationship between PD-L1 expression and 18F-FDG uptake in gastric cancer.
Ruohua Chen, Yumei Chen, Gang Huang, Jianjun Liu.
Aging (Albany NY), 2019 Dec 19; 11(24). PMID: 31848322    Free PMC article.
Overcoming malignant cell-based mechanisms of resistance to immune checkpoint blockade antibodies.
Reham Ajina, David J Zahavi, Yong-Wei Zhang, Louis M Weiner.
Semin Cancer Biol, 2019 Dec 24; 65. PMID: 31866479    Free PMC article.
Review.
Hashimoto's thyroiditis attenuates progression of papillary thyroid carcinoma: deciphering immunological links.
Oksana Sulaieva, Oleksii Selezniov, +5 authors, Marina Ivanova.
Heliyon, 2020 Jan 16; 6(1). PMID: 31938743    Free PMC article.
Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy.
Victoria Klepsch, Maria Pommermayr, +3 authors, Gottfried Baier.
Cell Commun Signal, 2020 Jan 16; 18(1). PMID: 31937317    Free PMC article.
Current Status of Immunotherapy for Lung Cancer and Future Perspectives.
Ho Cheol Kim, Chang Min Choi.
Tuberc Respir Dis (Seoul), 2020 Jan 07; 83(1). PMID: 31905428    Free PMC article.
Review.
Therapeutic Co-targeting of WEE1 and ATM Downregulates PD-L1 Expression in Pancreatic Cancer.
Mei Hua Jin, Ah-Rong Nam, +3 authors, Do-Youn Oh.
Cancer Res Treat, 2019 Jul 12; 52(1). PMID: 31291716    Free PMC article.
2B4 but not PD-1 blockade improves mortality in septic animals with preexisting malignancy.
Ching-Wen Chen, Ming Xue, +3 authors, Mandy L Ford.
JCI Insight, 2019 Nov 15; 4(22). PMID: 31723059    Free PMC article.
Mutation-derived Neoantigen-specific T-cell Responses in Multiple Myeloma.
Deepak Perumal, Naoko Imai, +14 authors, Samir Parekh.
Clin Cancer Res, 2019 Dec 21; 26(2). PMID: 31857430    Free PMC article.
Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival.
Oscar Brück, Olli Dufva, +14 authors, Satu Mustjoki.
Blood Adv, 2020 Jan 23; 4(2). PMID: 31968078    Free PMC article.
Precision Medicine in Oncology and Immuno-Oncology: Where We Stand and Where We're Headed.
Jürgen Scheuenpflug.
Biomed Hub, 2017 Nov 21; 2(Suppl 1). PMID: 31988938    Free PMC article.
Review.
HSP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumors.
Kwon-Ho Song, Se Jin Oh, +13 authors, Tae Woo Kim.
Nat Commun, 2020 Jan 30; 11(1). PMID: 31992715    Free PMC article.
Prognostic impact of PD-L1 expression in correlation with neutrophil-to-lymphocyte ratio in squamous cell carcinoma of the lung.
Yuko Tashima, Taiji Kuwata, +7 authors, Fumihiro Tanaka.
Sci Rep, 2020 Jan 29; 10(1). PMID: 31988315    Free PMC article.
Overexpression of B7H5/CD28H is associated with worse survival in human gastric cancer.
Can Hu, Zhiyuan Xu, +9 authors, Xiangdong Cheng.
J Cell Mol Med, 2019 Dec 29; 24(2). PMID: 31883303    Free PMC article.
Tumor immune response and immunotherapy in gastric cancer.
Yoonjin Kwak, An Na Seo, Hee Eun Lee, Hye Seung Lee.
J Pathol Transl Med, 2019 Nov 02; 54(1). PMID: 31674166    Free PMC article.
Review.
Local heroes or villains: tissue-resident memory T cells in human health and disease.
S C Sasson, C L Gordon, +2 authors, L K Mackay.
Cell Mol Immunol, 2020 Jan 24; 17(2). PMID: 31969685    Free PMC article.
Review.
Screening and Identifying Immune-Related Cells and Genes in the Tumor Microenvironment of Bladder Urothelial Carcinoma: Based on TCGA Database and Bioinformatics.
Jinlong Cao, Xin Yang, +5 authors, Junqiang Tian.
Front Oncol, 2020 Feb 06; 9. PMID: 32010623    Free PMC article.
Beyond PD-L1 Markers for Lung Cancer Immunotherapy.
Kamila Wojas-Krawczyk, Ewa Kalinka, +2 authors, Janusz Milanowski.
Int J Mol Sci, 2019 Apr 21; 20(8). PMID: 31003463    Free PMC article.
Review.
Antigen-loaded monocyte administration induces potent therapeutic antitumor T cell responses.
Min-Nung Huang, Lowell T Nicholson, +9 authors, Michael D Gunn.
J Clin Invest, 2019 Oct 30; 130(2). PMID: 31661470    Free PMC article.
Resistance Mechanism of PD-1/PD-L1 Blockade in the Cancer-Immunity Cycle.
Yuan Zhuang, Chang Liu, Jiaqing Liu, Guang Li.
Onco Targets Ther, 2020 Feb 06; 13. PMID: 32021257    Free PMC article.
Review.
Directing Traffic: How to Effectively Drive T Cells into Tumors.
Annabelle J Anandappa, Catherine J Wu, Patrick A Ott.
Cancer Discov, 2020 Jan 25; 10(2). PMID: 31974169    Free PMC article.
Review.
Immunological microenvironment gene expression in patients with diffuse large B cell non Hodgkin lymphoma.
Nesreen G Elhelbawy, Adel A H Nassar, +2 authors, Eman Ae Badr.
Biochem Biophys Rep, 2020 Feb 07; 21. PMID: 32025577    Free PMC article.
A TLR7 agonist strengthens T and NK cell function during BRAF-targeted therapy in a preclinical melanoma model.
Lydia Bellmann, Giuseppe Cappellano, +7 authors, Patrizia Stoitzner.
Int J Cancer, 2019 Nov 09; 146(5). PMID: 31702822    Free PMC article.
Combination immune checkpoint inhibitors with platinum-based chemotherapy in advanced non-small cell lung cancer: what's known and what's next.
Tao Jiang, Caicun Zhou, Jie Hu, Yuanlin Song.
Transl Lung Cancer Res, 2020 Feb 11; 8(Suppl 4). PMID: 32038935    Free PMC article.
Predictive biomarkers for immune checkpoint blockade and opportunities for combination therapies.
Hongxing Shen, Eddy Shih-Hsin Yang, +4 authors, Lewis Zhichang Shi.
Genes Dis, 2020 Feb 12; 6(3). PMID: 32042863    Free PMC article.
Review.
Screening and Identification of Key Biomarkers for Bladder Cancer: A Study Based on TCGA and GEO Data.
Yingkun Xu, Guangzhen Wu, +9 authors, Qinghua Xia.
Biomed Res Int, 2020 Feb 13; 2020. PMID: 32047816    Free PMC article.
Promotion on NLRC5 upregulating MHC-I expression by IFN-γ in MHC-I-deficient breast cancer cells.
Ming-Zhen Zhao, Yu Sun, +3 authors, Li-Xin Sun.
Immunol Res, 2020 Jan 05; 67(6). PMID: 31900803
Immune biological rationales for the design of combined radio- and immunotherapies.
Michael Hader, Benjamin Frey, +2 authors, Udo S Gaipl.
Cancer Immunol Immunother, 2020 Jan 19; 69(2). PMID: 31953578    Free PMC article.
Review.
Tumor Time-Course Predicts Overall Survival in Non-Small Cell Lung Cancer Patients Treated with Atezolizumab: Dependency on Follow-Up Time.
Ida Netterberg, René Bruno, +4 authors, Lena E Friberg.
CPT Pharmacometrics Syst Pharmacol, 2020 Jan 29; 9(2). PMID: 31991070    Free PMC article.
Modulation of the immune microenvironment by tumor-intrinsic oncogenic signaling.
Kim Bich Nguyen, Stefani Spranger.
J Cell Biol, 2019 Dec 10; 219(1). PMID: 31816057    Free PMC article.
Review.
Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells.
Matthew B Dong, Guangchuan Wang, +17 authors, Sidi Chen.
Cell, 2019 Aug 24; 178(5). PMID: 31442407    Free PMC article.
Immunotherapy: Pancreatic Cancer and Extrahepatic Biliary Tract Cancer.
Lukas Perkhofer, Alica K Beutel, Thomas J Ettrich.
Visc Med, 2019 Jul 18; 35(1). PMID: 31312647    Free PMC article.
Review.
TYK2 in Tumor Immunosurveillance.
Anzhelika Karjalainen, Stephen Shoebridge, +5 authors, Mathias Müller.
Cancers (Basel), 2020 Jan 16; 12(1). PMID: 31936322    Free PMC article.
Review.
Nanomaterials for modulating innate immune cells in cancer immunotherapy.
Quoc-Viet Le, Geon Yang, +3 authors, Yu-Kyoung Oh.
Asian J Pharm Sci, 2020 Feb 28; 14(1). PMID: 32104435    Free PMC article.
Review.
Immunotherapy with immune checkpoint inhibitors in colorectal cancer: what is the future beyond deficient mismatch-repair tumours?
Nicolas Huyghe, Paméla Baldin, Marc Van den Eynde.
Gastroenterol Rep (Oxf), 2020 Feb 28; 8(1). PMID: 32104582    Free PMC article.
Review.
Peripheral Blood Platelet-Lymphocyte Ratio Is Good Predictor of Chemosensitivity and Prognosis in Gastric Cancer Patients.
Yuka Ohe, Sachio Fushida, +7 authors, Tetsuo Ohta.
Cancer Manag Res, 2020 Feb 29; 12. PMID: 32110104    Free PMC article.
Clinical significance of circulating soluble immune checkpoint proteins in sorafenib-treated patients with advanced hepatocellular carcinoma.
Minh Phuong Dong, Masaru Enomoto, +11 authors, Norifumi Kawada.
Sci Rep, 2020 Feb 27; 10(1). PMID: 32099055    Free PMC article.
CCL2-CCR2 axis recruits tumor associated macrophages to induce immune evasion through PD-1 signaling in esophageal carcinogenesis.
Hui Yang, Qiannan Zhang, +7 authors, Xudong Jia.
Mol Cancer, 2020 Feb 28; 19(1). PMID: 32103760    Free PMC article.
Illuminating the Onco-GPCRome: Novel G protein-coupled receptor-driven oncocrine networks and targets for cancer immunotherapy.
Victoria Wu, Huwate Yeerna, +7 authors, J Silvio Gutkind.
J Biol Chem, 2019 Jun 07; 294(29). PMID: 31171722    Free PMC article.
Review.
Epithelial-mesenchymal transition gene signature is associated with prognosis and tumor microenvironment in head and neck squamous cell carcinoma.
Ah Ra Jung, Chan-Hun Jung, +2 authors, Young-Gyu Eun.
Sci Rep, 2020 Feb 29; 10(1). PMID: 32107458    Free PMC article.
Insights Into Lung Cancer Immune-Based Biology, Prevention, and Treatment.
Sara Saab, Hussein Zalzale, +3 authors, Humam Kadara.
Front Immunol, 2020 Mar 03; 11. PMID: 32117295    Free PMC article.
Review.
Expression of TIM3/VISTA checkpoints and the CD68 macrophage-associated marker correlates with anti-PD1/PDL1 resistance: implications of immunogram heterogeneity.
Shumei Kato, Ryosuke Okamura, +11 authors, Razelle Kurzrock.
Oncoimmunology, 2020 Mar 03; 9(1). PMID: 32117584    Free PMC article.
Helper T cell-dominant tertiary lymphoid structures are associated with disease relapse of advanced colorectal cancer.
Kyoko Yamaguchi, Mamoru Ito, +11 authors, Eishi Baba.
Oncoimmunology, 2020 Mar 03; 9(1). PMID: 32117589    Free PMC article.
Biomimetic Glyconanoparticle Vaccine for Cancer Immunotherapy.
Eliran Moshe Reuven, Shani Leviatan Ben-Arye, +8 authors, Vered Padler-Karavani.
ACS Nano, 2019 Mar 07; 13(3). PMID: 30840433    Free PMC article.
PD-L1 expression combined with microsatellite instability/CD8+ tumor infiltrating lymphocytes as a useful prognostic biomarker in gastric cancer.
Toshiaki Morihiro, Shinji Kuroda, +10 authors, Toshiyoshi Fujiwara.
Sci Rep, 2019 Mar 16; 9(1). PMID: 30874607    Free PMC article.
The silencing of indoleamine 2,3-dioxygenase 1 (IDO1) in dendritic cells by siRNA-loaded lipid nanoparticles enhances cell-based cancer immunotherapy.
Rikito Endo, Takashi Nakamura, +2 authors, Hideyoshi Harashima.
Sci Rep, 2019 Aug 07; 9(1). PMID: 31383907    Free PMC article.
Novel, genetically induced mouse model that recapitulates the histological morphology and immunosuppressive tumor microenvironment of metastatic peritoneal carcinomatosis.
Ssu-Hsueh Tseng, Sung-Taek Park, +5 authors, Chien-Fu Hung.
J Immunother Cancer, 2020 Mar 01; 8(1). PMID: 32111730    Free PMC article.
TriMix and tumor antigen mRNA electroporated dendritic cell vaccination plus ipilimumab: link between T-cell activation and clinical responses in advanced melanoma.
Brenda De Keersmaecker, Sofie Claerhout, +5 authors, Kris Thielemans.
J Immunother Cancer, 2020 Mar 03; 8(1). PMID: 32114500    Free PMC article.
Noncoding RNAs in cancer immunity: functions, regulatory mechanisms, and clinical application.
Le Zhang, Xiaonan Xu, Xiulan Su.
Mol Cancer, 2020 Mar 04; 19(1). PMID: 32122338    Free PMC article.
Review.
Development of a PD-L1 Complementary Diagnostic Immunohistochemistry Assay (SP142) for Atezolizumab.
Bharathi Vennapusa, Brian Baker, +17 authors, Zachary Boyd.
Appl Immunohistochem Mol Morphol, 2018 Jan 19; 27(2). PMID: 29346180    Free PMC article.
Lessons learned from the blockade of immune checkpoints in cancer immunotherapy.
Xiaolei Li, Changshun Shao, Yufang Shi, Weidong Han.
J Hematol Oncol, 2018 Feb 28; 11(1). PMID: 29482595    Free PMC article.
Highly Cited. Review.
Functional genomics: paving the way for more successful cancer immunotherapy.
Reham Ajina, Danielle Zamalin, Louis M Weiner.
Brief Funct Genomics, 2018 May 16; 18(2). PMID: 29762641    Free PMC article.
Review.
Oncogenic BRAFV600E Governs Regulatory T-cell Recruitment during Melanoma Tumorigenesis.
Tamer B Shabaneh, Aleksey K Molodtsov, +7 authors, Mary Jo Turk.
Cancer Res, 2018 Jul 22; 78(17). PMID: 30026331    Free PMC article.
In situ genetic engineering of tumors for long-lasting and systemic immunotherapy.
Stephany Y Tzeng, Kisha K Patel, +3 authors, Jordan J Green.
Proc Natl Acad Sci U S A, 2020 Feb 09; 117(8). PMID: 32034097    Free PMC article.
Wnt Signaling Cascade in Dendritic Cells and Regulation of Anti-tumor Immunity.
Amol Suryawanshi, Mohamed S Hussein, Puttur D Prasad, Santhakumar Manicassamy.
Front Immunol, 2020 Mar 07; 11. PMID: 32132993    Free PMC article.
Review.
A PK/PD Analysis of Circulating Biomarkers and Their Relationship to Tumor Response in Atezolizumab-Treated non-small Cell Lung Cancer Patients.
Ida Netterberg, Chi-Chung Li, +5 authors, Lena E Friberg.
Clin Pharmacol Ther, 2018 Jul 31; 105(2). PMID: 30058723    Free PMC article.
Anti-drug antibodies to LMB-100 are enhanced by mAbs targeting OX40 and CTLA4 but not by mAbs targeting PD1 or PDL-1.
Ronit Mazor, Emily King, Ira Pastan.
Cell Immunol, 2018 Sep 15; 334. PMID: 30213644    Free PMC article.
Immune biomarkers for predicting response to adoptive cell transfer as cancer treatment.
Ianthe A E M van Belzen, Can Kesmir.
Immunogenetics, 2018 Sep 21; 71(2). PMID: 30232514    Free PMC article.
Review.
Long-term Clinical Outcomes and Biomarker Analyses of Atezolizumab Therapy for Patients With Metastatic Triple-Negative Breast Cancer: A Phase 1 Study.
Leisha A Emens, Cristina Cruz, +16 authors, Peter Schmid.
JAMA Oncol, 2018 Sep 23; 5(1). PMID: 30242306    Free PMC article.
Highly Cited.
Biomaterials for vaccine-based cancer immunotherapy.
Rui Zhang, Margaret M Billingsley, Michael J Mitchell.
J Control Release, 2018 Oct 13; 292. PMID: 30312721    Free PMC article.
Review.
Atezolizumab Plus nab-Paclitaxel in the Treatment of Metastatic Triple-Negative Breast Cancer With 2-Year Survival Follow-up: A Phase 1b Clinical Trial.
Sylvia Adams, Jennifer R Diamond, +9 authors, John Powderly.
JAMA Oncol, 2018 Oct 23; 5(3). PMID: 30347025    Free PMC article.
Highly Cited.
A Novel Engineered Small Protein for Positron Emission Tomography Imaging of Human Programmed Death Ligand-1: Validation in Mouse Models and Human Cancer Tissues.
Arutselvan Natarajan, Chirag B Patel, +3 authors, Sanjiv S Gambhir.
Clin Cancer Res, 2018 Oct 31; 25(6). PMID: 30373750    Free PMC article.
Association of Cancer Immunotherapy With Acute Macular Neuroretinopathy and Diffuse Retinal Venulitis.
Leisha A Emens, S Lindsey Davis, +10 authors, Daniela Ferrara.
JAMA Ophthalmol, 2018 Nov 02; 137(1). PMID: 30383154    Free PMC article.
Cytokines in clinical cancer immunotherapy.
Pedro Berraondo, Miguel F Sanmamed, +7 authors, Ignacio Melero.
Br J Cancer, 2018 Nov 11; 120(1). PMID: 30413827    Free PMC article.
Highly Cited. Review.
RNA-Modified T Cells Mediate Effective Delivery of Immunomodulatory Cytokines to Brain Tumors.
Fernanda Pohl-Guimarães, Changlin Yang, +6 authors, Duane A Mitchell.
Mol Ther, 2018 Nov 19; 27(4). PMID: 30448196    Free PMC article.
MMP-9 inhibition promotes anti-tumor immunity through disruption of biochemical and physical barriers to T-cell trafficking to tumors.
Vladi Juric, Chris O'Sullivan, +8 authors, Amanda Mikels-Vigdal.
PLoS One, 2018 Dec 01; 13(11). PMID: 30500835    Free PMC article.
Subgrouping breast cancer patients based on immune evasion mechanisms unravels a high involvement of transforming growth factor-beta and decoy receptor 3.
Mayassa J Bou-Dargham, Yuhang Liu, Qing-Xiang Amy Sang, Jinfeng Zhang.
PLoS One, 2018 Dec 05; 13(12). PMID: 30513096    Free PMC article.
Dendritic Cell Membrane Vesicles for Activation and Maintenance of Antigen-Specific T Cells.
Lukasz J Ochyl, James J Moon.
Adv Healthc Mater, 2018 Dec 20; 8(4). PMID: 30565895    Free PMC article.
Combination Strategies to Optimize Efficacy of Dendritic Cell-Based Immunotherapy.
Mandy van Gulijk, Floris Dammeijer, Joachim G J V Aerts, Heleen Vroman.
Front Immunol, 2018 Dec 21; 9. PMID: 30568653    Free PMC article.
Review.
Real-world benefit of nivolumab in a Canadian non-small-cell lung cancer cohort.
R A Juergens, C Mariano, +11 authors, C Butts.
Curr Oncol, 2019 Jan 05; 25(6). PMID: 30607113    Free PMC article.
Dendritic Cells and CD8 T Cell Immunity in Tumor Microenvironment.
Chunmei Fu, Aimin Jiang.
Front Immunol, 2019 Jan 09; 9. PMID: 30619378    Free PMC article.
Highly Cited. Review.
Translation control of the immune checkpoint in cancer and its therapeutic targeting.
Yichen Xu, Mauro Poggio, +18 authors, Davide Ruggero.
Nat Med, 2019 Jan 16; 25(2). PMID: 30643286    Free PMC article.
Highly Cited.
Broadening the Impact of Immunotherapy to Pancreatic Cancer: Challenges and Opportunities.
Vinod P Balachandran, Gregory L Beatty, Stephanie K Dougan.
Gastroenterology, 2019 Jan 21; 156(7). PMID: 30660727    Free PMC article.
Highly Cited. Review.
A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer.
Lucia D'Amico, Ulrike Menzel, +16 authors, Alfred Zippelius.
J Immunother Cancer, 2019 Jan 23; 7(1). PMID: 30665463    Free PMC article.
Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors.
Jeffrey M Conroy, Sarabjot Pabla, +37 authors, Carl Morrison.
J Immunother Cancer, 2019 Jan 27; 7(1). PMID: 30678715    Free PMC article.
OMIP-054: Broad Immune Phenotyping of Innate and Adaptive Leukocytes in the Brain, Spleen, and Bone Marrow of an Orthotopic Murine Glioblastoma Model by Mass Cytometry.
Sophie A Dusoswa, Jan Verhoeff, Juan J Garcia-Vallejo.
Cytometry A, 2019 Feb 01; 95(4). PMID: 30701669    Free PMC article.
Therapeutic Potential of Natural Killer Cells in Gastric Cancer.
Yu Du, Yongchang Wei.
Front Immunol, 2019 Feb 06; 9. PMID: 30719024    Free PMC article.
Review.
Vaccine Strategies to Improve Anti-cancer Cellular Immune Responses.
Karim Vermaelen.
Front Immunol, 2019 Feb 07; 10. PMID: 30723469    Free PMC article.
Highly Cited. Review.
Clinical outcomes of advanced stage cancer patients treated with sequential immunotherapy in phase 1 clinical trials.
Dylan J Martini, Yuan Liu, +19 authors, Mehmet Asim Bilen.
Invest New Drugs, 2019 Feb 07; 37(6). PMID: 30725388    Free PMC article.
TCR Repertoire Analysis Reveals Mobilization of Novel CD8+ T Cell Clones Into the Cancer-Immunity Cycle Following Anti-CD4 Antibody Administration.
Hiroyasu Aoki, Satoshi Ueha, +5 authors, Kouji Matsushima.
Front Immunol, 2019 Feb 09; 9. PMID: 30733724    Free PMC article.
Comparative efficacy and safety of first-line treatments for advanced non-small cell lung cancer with immune checkpoint inhibitors: A systematic review and meta-analysis.
Rui Chen, Xiaoming Hou, Liping Yang, Da Zhao.
Thorac Cancer, 2019 Feb 09; 10(4). PMID: 30734504    Free PMC article.
Systematic Review.
Prognostic impact of CD8 and programmed death-ligand 1 expression in patients with resectable non-small cell lung cancer.
Seok-Hyun Kim, Se-Il Go, +6 authors, Gyeong-Won Lee.
Br J Cancer, 2019 Feb 13; 120(5). PMID: 30745585    Free PMC article.
Immunotherapy for skin cancer.
Kelly G Paulson, Miranda C Lahman, Aude G Chapuis, Isaac Brownell.
Int Immunol, 2019 Feb 13; 31(7). PMID: 30753483    Free PMC article.
Review.
Advances in immunotherapy delivery from implantable and injectable biomaterials.
David G Leach, Simon Young, Jeffrey D Hartgerink.
Acta Biomater, 2019 Feb 17; 88. PMID: 30771535    Free PMC article.
Review.
Balancing the Checkpoint: Managing Colitis Associated with Dual Checkpoint Inhibitors and High-Dose Aspirin.
Muhammad B Hammami, Ryan Gill, +4 authors, Michael G Kattah.
Dig Dis Sci, 2019 Feb 20; 64(3). PMID: 30778872
Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo.
Adan Codina, Paul A Renauer, +16 authors, Sidi Chen.
Cell Syst, 2019 Feb 25; 8(2). PMID: 30797773    Free PMC article.
Cold Tumors: A Therapeutic Challenge for Immunotherapy.
Paola Bonaventura, Tala Shekarian, +5 authors, Stéphane Depil.
Front Immunol, 2019 Feb 26; 10. PMID: 30800125    Free PMC article.
Highly Cited. Review.
Paraneoplastic autoimmunity and small-cell lung cancer: Neurological and serological accompaniments.
Anastasia Zekeridou, Masoud Majed, Ioannis Heliopoulos, Vanda A Lennon.
Thorac Cancer, 2019 Feb 28; 10(4). PMID: 30810271    Free PMC article.
Gynecological Cancers Translational, Research Implementation, and Harmonization: Gynecologic Cancer InterGroup Consensus and Still Open Questions.
Marina Bagnoli, Ting Yan Shi, +17 authors, Delia Mezzanzanica.
Cells, 2019 Mar 01; 8(3). PMID: 30813545    Free PMC article.
Review.
Neoantigen identification strategies enable personalized immunotherapy in refractory solid tumors.
Fangjun Chen, Zhengyun Zou, +14 authors, Baorui Liu.
J Clin Invest, 2019 Mar 06; 129(5). PMID: 30835255    Free PMC article.
Highly Cited.
VEGF in Signaling and Disease: Beyond Discovery and Development.
Rajendra S Apte, Daniel S Chen, Napoleone Ferrara.
Cell, 2019 Mar 09; 176(6). PMID: 30849371    Free PMC article.
Highly Cited. Review.
Phase 1/2 study of epacadostat in combination with ipilimumab in patients with unresectable or metastatic melanoma.
Geoffrey T Gibney, Omid Hamid, +10 authors, Jeffrey S Weber.
J Immunother Cancer, 2019 Mar 22; 7(1). PMID: 30894212    Free PMC article.
Critical role of kinase activity of hematopoietic progenitor kinase 1 in anti-tumor immune surveillance.
Jinqi Liu, Joshua Curtin, +19 authors, Luisa Salter-Cid.
PLoS One, 2019 Mar 27; 14(3). PMID: 30913212    Free PMC article.
Activating cGAS-STING pathway for the optimal effect of cancer immunotherapy.
Anping Li, Ming Yi, +3 authors, Kongming Wu.
J Hematol Oncol, 2019 Apr 03; 12(1). PMID: 30935414    Free PMC article.
Highly Cited. Review.
Could the menagerie of the gut microbiome really cure cancer? Hope or hype.
Muhammad Bilal Abid.
J Immunother Cancer, 2019 Apr 04; 7(1). PMID: 30940203    Free PMC article.
CD91 on dendritic cells governs immunosurveillance of nascent, emerging tumors.
Abigail L Sedlacek, Theodore P Younker, +4 authors, Robert J Binder.
JCI Insight, 2019 Apr 05; 4(7). PMID: 30944251    Free PMC article.
Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory.
Mauro Poggio, Tianyi Hu, +8 authors, Robert Blelloch.
Cell, 2019 Apr 06; 177(2). PMID: 30951669    Free PMC article.
Highly Cited.
Beyond the tumour microenvironment.
Lucie Laplane, Dorothée Duluc, +2 authors, Thomas Pradeu.
Int J Cancer, 2019 Apr 17; 145(10). PMID: 30989643    Free PMC article.
Review.
Combination regimens with PD-1/PD-L1 immune checkpoint inhibitors for gastrointestinal malignancies.
Dongxu Wang, Jianzhen Lin, +7 authors, Haitao Zhao.
J Hematol Oncol, 2019 Apr 25; 12(1). PMID: 31014381    Free PMC article.
Review.
STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models.
Weiqing Jing, Donna McAllister, +5 authors, Michael B Dwinell.
J Immunother Cancer, 2019 May 01; 7(1). PMID: 31036082    Free PMC article.
A network approach to developing immuno-oncology combinations in Canada.
V Higenell, R Fajzel, +11 authors, S Verma.
Curr Oncol, 2019 May 03; 26(2). PMID: 31043804    Free PMC article.
Quantitative Systems Pharmacology: An Exemplar Model-Building Workflow With Applications in Cardiovascular, Metabolic, and Oncology Drug Development.
Gabriel Helmlinger, Victor Sokolov, +11 authors, Robert C Penland.
CPT Pharmacometrics Syst Pharmacol, 2019 May 16; 8(6). PMID: 31087533    Free PMC article.
Review.
Paired whole exome and transcriptome analyses for the Immunogenomic changes during concurrent chemoradiotherapy in esophageal squamous cell carcinoma.
Sehhoon Park, Je-Gun Joung, +10 authors, Jong-Mu Sun.
J Immunother Cancer, 2019 May 18; 7(1). PMID: 31097034    Free PMC article.
Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop.
Davide Bedognetti, Michele Ceccarelli, +53 authors, Society for Immunotherapy of Cancer (SITC) Cancer Immune Responsiveness Task Force and Working Groups.
J Immunother Cancer, 2019 May 23; 7(1). PMID: 31113486    Free PMC article.
Review.
Patients Selection for Immunotherapy in Solid Tumors: Overcome the Naïve Vision of a Single Biomarker.
Diego Signorelli, Patrizia Giannatempo, +11 authors, Immune-Oncology YOUNG Group.
Biomed Res Int, 2019 Jun 11; 2019. PMID: 31179334    Free PMC article.
Review.
Potential immune escape mechanisms underlying the distinct clinical outcome of immune checkpoint blockades in small cell lung cancer.
Yaru Tian, Xiaoyang Zhai, +2 authors, Jinming Yu.
J Hematol Oncol, 2019 Jun 30; 12(1). PMID: 31253167    Free PMC article.
Review.
NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices.
Hongqian Chu, Jian Zhao, +2 authors, Lele Li.
Nat Commun, 2019 Jun 30; 10(1). PMID: 31253798    Free PMC article.
Integrating nanomedicine into clinical radiotherapy regimens.
Allison N DuRoss, Megan J Neufeld, +2 authors, Conroy Sun.
Adv Drug Deliv Rev, 2019 Jul 08; 144. PMID: 31279729    Free PMC article.
Review.
Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts.
Karin Schaeuble, Hélène Cannelle, +5 authors, Sanjiv A Luther.
PLoS Biol, 2019 Jul 16; 17(7). PMID: 31306410    Free PMC article.
Macrophage-Mediated Subversion of Anti-Tumour Immunity.
Valeria Quaranta, Michael C Schmid.
Cells, 2019 Jul 25; 8(7). PMID: 31331034    Free PMC article.
Review.
Quantifying immune-based counterselection of somatic mutations.
Fan Yang, Dae-Kyum Kim, +4 authors, Frederick P Roth.
PLoS Genet, 2019 Jul 26; 15(7). PMID: 31344031    Free PMC article.
Circulating tumor cells in pulmonary vein and peripheral arterial provide a metric for PD-L1 diagnosis and prognosis of patients with non-small cell lung cancer.
Jingsi Dong, Daxing Zhu, +7 authors, Qinghua Zhou.
PLoS One, 2019 Jul 28; 14(7). PMID: 31348821    Free PMC article.
Role of the dynamic tumor microenvironment in controversies regarding immune checkpoint inhibitors for the treatment of non-small cell lung cancer (NSCLC) with EGFR mutations.
Anqi Lin, Ting Wei, +2 authors, Jian Zhang.
Mol Cancer, 2019 Sep 19; 18(1). PMID: 31526368    Free PMC article.
Review.
Integrative genomic analyses of APOBEC-mutational signature, expression and germline deletion of APOBEC3 genes, and immunogenicity in multiple cancer types.
Zhishan Chen, Wanqing Wen, +6 authors, Xingyi Guo.
BMC Med Genomics, 2019 Sep 20; 12(1). PMID: 31533728    Free PMC article.
Human immunoglobulin G hinge regulates agonistic anti-CD40 immunostimulatory and antitumour activities through biophysical flexibility.
Xiaobo Liu, Yingjie Zhao, +8 authors, Fubin Li.
Nat Commun, 2019 Sep 29; 10(1). PMID: 31562320    Free PMC article.
Multiple Targets of the Canonical WNT/β-Catenin Signaling in Cancers.
Yves Lecarpentier, Olivier Schussler, Jean-Louis Hébert, Alexandre Vallée.
Front Oncol, 2019 Dec 06; 9. PMID: 31803621    Free PMC article.
Review.
Development of patient-derived xenograft models of prostate cancer for maintaining tumor heterogeneity.
Changhong Shi, Xue Chen, Dengxu Tan.
Transl Androl Urol, 2019 Dec 07; 8(5). PMID: 31807428    Free PMC article.
Review.
Immunosurveillance and Immunoediting of Lung Cancer: Current Perspectives and Challenges.
Kei Kunimasa, Taichiro Goto.
Int J Mol Sci, 2020 Jan 23; 21(2). PMID: 31963413    Free PMC article.
Review.
Immune Modulation by Telomerase-Specific Oncolytic Adenovirus Synergistically Enhances Antitumor Efficacy with Anti-PD1 Antibody.
Nobuhiko Kanaya, Shinji Kuroda, +13 authors, Toshiyoshi Fujiwara.
Mol Ther, 2020 Jan 29; 28(3). PMID: 31991110    Free PMC article.
Peripheral Blood Markers Identify Risk of Immune-Related Toxicity in Advanced Non-Small Cell Lung Cancer Treated with Immune-Checkpoint Inhibitors.
Alberto Pavan, Lorenzo Calvetti, +7 authors, Laura Bonanno.
Oncologist, 2019 Apr 25; 24(8). PMID: 31015312    Free PMC article.
Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients.
Sander Tuit, Camilla Salvagno, +7 authors, Joachim L Schultze.
Cell Rep, 2019 Oct 31; 29(5). PMID: 31665635    Free PMC article.
Substantial tumor regression in prostate cancer patient with extensive skeletal metastases upon Immunotherapy (APCEDEN): A case report.
Bandana Sharan, Srikanth Chiliveru, +4 authors, Chaitanya Kumar.
Medicine (Baltimore), 2020 Feb 23; 99(8). PMID: 32080073    Free PMC article.
Peripheral blood immune cell-based biomarkers in anti-PD-1/PD-L1 therapy.
Kyung Hwan Kim, Chang Gon Kim, Eui-Cheol Shin.
Immune Netw, 2020 Mar 12; 20(1). PMID: 32158596    Free PMC article.
Review.
Development of [18F]FPy-WL12 as a PD-L1 Specific PET Imaging Peptide.
Wojciech G Lesniak, Ronnie C Mease, +7 authors, Sridhar Nimmagadda.
Mol Imaging, 2019 Jun 13; 18. PMID: 31187691    Free PMC article.
[Chinese Experts Consensus on Immune Checkpoint Inhibitors for Non-small Cell Lung Cancer (2019 version)].
Caicun Zhou, Jie Wang, +13 authors, Shukui Qin.
Zhongguo Fei Ai Za Zhi, 2020 Feb 26; 23(2). PMID: 32093450    Free PMC article.
Impaired circulating myeloid CD1c+ dendritic cell function in human glioblastoma is restored by p38 inhibition - implications for the next generation of DC vaccines.
Jason Adhikaree, Hester Ann Franks, +6 authors, Poulam Manubhai Patel.
Oncoimmunology, 2019 May 31; 8(7). PMID: 31143512    Free PMC article.
Identification of immune cells and mRNA associated with prognosis of gastric cancer.
Mingming Wang, Zedong Li, +4 authors, Jun Zhou.
BMC Cancer, 2020 Mar 14; 20(1). PMID: 32164594    Free PMC article.
Noninvasive PET tracking of post-transplant gut microbiota in living mice.
Yanpu Wang, Chenran Zhang, +6 authors, Zhaofei Liu.
Eur J Nucl Med Mol Imaging, 2020 Jan 04; 47(4). PMID: 31897587
Resistance Mechanisms and Barriers to Successful Immunotherapy for Treating Glioblastoma.
Jason Adhikaree, Julia Moreno-Vicente, +2 authors, Poulam M Patel.
Cells, 2020 Jan 25; 9(2). PMID: 31973059    Free PMC article.
Review.
Preclinical and Clinical Evidence of Immune Responses Triggered in Oncologic Photodynamic Therapy: Clinical Recommendations.
Irati Beltrán Hernández, Yingxin Yu, +2 authors, Sabrina Oliveira.
J Clin Med, 2020 Jan 30; 9(2). PMID: 31991650    Free PMC article.
Review.
Phage Display-Based Nanotechnology Applications in Cancer Immunotherapy.
Martina Goracci, Ymera Pignochino, Serena Marchiò.
Molecules, 2020 Feb 23; 25(4). PMID: 32075083    Free PMC article.
Review.
Decitabine Augments Chemotherapy-Induced PD-L1 Upregulation for PD-L1 Blockade in Colorectal Cancer.
Kevin Chih-Yang Huang, Shu-Fen Chiang, +5 authors, K S Clifford Chao.
Cancers (Basel), 2020 Feb 23; 12(2). PMID: 32079180    Free PMC article.
Predictive Value of Soluble PD-1, PD-L1, VEGFA, CD40 Ligand and CD44 for Nivolumab Therapy in Advanced Non-Small Cell Lung Cancer: A Case-Control Study.
Manuela Tiako Meyo, Anne Jouinot, +16 authors, Benoit Blanchet.
Cancers (Basel), 2020 Feb 23; 12(2). PMID: 32085544    Free PMC article.
Circulating Tumor Cells and Metabolic Parameters in NSCLC Patients Treated with Checkpoint Inhibitors.
Angelo Castello, Francesco Giuseppe Carbone, +4 authors, Egesta Lopci.
Cancers (Basel), 2020 Feb 26; 12(2). PMID: 32092983    Free PMC article.
Human Hepatic Cancer Stem Cells (HCSCs) Markers Correlated With Immune Infiltrates Reveal Prognostic Significance of Hepatocellular Carcinoma.
Xiaopu Sang, Fenfang Wu, +5 authors, Anlong Xu.
Front Genet, 2020 Mar 19; 11. PMID: 32184801    Free PMC article.
RAF kinases are stabilized and required for dendritic cell differentiation and function.
Kristina Riegel, Janine Schlöder, +4 authors, Krishnaraj Rajalingam.
Cell Death Differ, 2019 Sep 22; 27(4). PMID: 31541179    Free PMC article.
The relative biological effectiveness of proton irradiation in dependence of DNA damage repair.
Simon Deycmar, Erica Faccin, +8 authors, Martin Pruschy.
Br J Radiol, 2019 Nov 07; 93(1107). PMID: 31687835    Free PMC article.
Review.
Breast cancer stem cell RNA-pulsed dendritic cells enhance tumor cell killing by effector T cells.
Nuttavut Sumransub, Niphat Jirapongwattana, +7 authors, Chanitra Thuwajit.
Oncol Lett, 2020 Mar 21; 19(3). PMID: 32194742    Free PMC article.
Modulation of tumor microenvironment for immunotherapy: focus on nanomaterial-based strategies.
Yun Liu, Jianfeng Guo, Leaf Huang.
Theranostics, 2020 Mar 21; 10(7). PMID: 32194857    Free PMC article.
Review.
The Combination Options and Predictive Biomarkers of PD-1/PD-L1 Inhibitors in Esophageal Cancer.
Hui Yang, Kunlun Wang, +4 authors, Ling Yuan.
Front Oncol, 2020 Mar 21; 10. PMID: 32195194    Free PMC article.
Review.
Tumor-associated antigens identified early in mouse mammary tumor development can be effective vaccine targets.
Sasha E Stanton, Ekram Gad, +2 authors, Mary L Disis.
Vaccine, 2019 May 28; 37(27). PMID: 31126858    Free PMC article.
Tumor neoantigens: from basic research to clinical applications.
Tao Jiang, Tao Shi, +5 authors, Caicun Zhou.
J Hematol Oncol, 2019 Sep 08; 12(1). PMID: 31492199    Free PMC article.
Highly Cited. Review.
Prospects for combining immune checkpoint blockade with PARP inhibition.
Anping Li, Ming Yi, +3 authors, Kongming Wu.
J Hematol Oncol, 2019 Sep 16; 12(1). PMID: 31521196    Free PMC article.
Review.
Consensus guidelines for the definition, detection and interpretation of immunogenic cell death.
Lorenzo Galluzzi, Ilio Vitale, +51 authors, Francesco M Marincola.
J Immunother Cancer, 2020 Mar 27; 8(1). PMID: 32209603    Free PMC article.
Review.
Prostaglandin E Receptor 4 Antagonist in Cancer Immunotherapy: Mechanisms of Action.
Yukinori Take, Shinichi Koizumi, Atsushi Nagahisa.
Front Immunol, 2020 Mar 27; 11. PMID: 32210957    Free PMC article.
Review.
Tyrosine kinase inhibitors and immunotherapy combinations in renal cell carcinoma.
Elie Rassy, Ronan Flippot, Laurence Albiges.
Ther Adv Med Oncol, 2020 Mar 28; 12. PMID: 32215057    Free PMC article.
Review.
Combination of host immune metabolic biomarkers for the PD-1 blockade cancer immunotherapy.
Ryusuke Hatae, Kenji Chamoto, +13 authors, Tasuku Honjo.
JCI Insight, 2019 Dec 20; 5(2). PMID: 31855576    Free PMC article.
Oncolytic vaccinia virus delivering tethered IL-12 enhances antitumor effects with improved safety.
Yan Ge, Haiyan Wang, +10 authors, David L Bartlett.
J Immunother Cancer, 2020 Mar 27; 8(1). PMID: 32209602    Free PMC article.
Armed oncolytic viruses: A kick-start for anti-tumor immunity.
J F de Graaf, L de Vor, R A M Fouchier, B G van den Hoogen.
Cytokine Growth Factor Rev, 2018 Mar 27; 41. PMID: 29576283    Free PMC article.
Highly Cited. Review.
Ibrutinib treatment inhibits breast cancer progression and metastasis by inducing conversion of myeloid-derived suppressor cells to dendritic cells.
Sanjay Varikuti, Bhawana Singh, +12 authors, Abhay R Satoskar.
Br J Cancer, 2020 Feb 07; 122(7). PMID: 32025027    Free PMC article.
Tumors attenuating the mitochondrial activity in T cells escape from PD-1 blockade therapy.
Alok Kumar, Kenji Chamoto, Partha S Chowdhury, Tasuku Honjo.
Elife, 2020 Mar 04; 9. PMID: 32122466    Free PMC article.
The role of cancer-derived microRNAs in cancer immune escape.
Ming Yi, Linping Xu, +3 authors, Kongming Wu.
J Hematol Oncol, 2020 Mar 31; 13(1). PMID: 32222150    Free PMC article.
Review.
CD29 identifies IFN-γ-producing human CD8+ T cells with an increased cytotoxic potential.
Benoît P Nicolet, Aurélie Guislain, +4 authors, Monika C Wolkers.
Proc Natl Acad Sci U S A, 2020 Mar 13; 117(12). PMID: 32161126    Free PMC article.
The immune infiltration in clear cell Renal Cell Carcinoma and their clinical implications: A study based on TCGA and GEO databases.
Qiufeng Pan, Longwang Wang, +2 authors, Bing Li.
J Cancer, 2020 Apr 02; 11(11). PMID: 32231726    Free PMC article.
Complementing the Cancer-Immunity Cycle.
Ruben Pio, Daniel Ajona, +2 authors, John D Lambris.
Front Immunol, 2019 Apr 30; 10. PMID: 31031765    Free PMC article.
Highly Cited. Review.
Tumor-targeted IL-12 combined with tumor resection yields a survival-favorable immune profile.
Qingnan Zhao, Jiemiao Hu, +9 authors, Shulin Li.
J Immunother Cancer, 2019 Jun 19; 7(1). PMID: 31208461    Free PMC article.
Next-generation immuno-oncology agents: current momentum shifts in cancer immunotherapy.
Chongxian Pan, Hongtao Liu, +4 authors, Lei Zheng.
J Hematol Oncol, 2020 Apr 05; 13(1). PMID: 32245497    Free PMC article.
Review.
Detection of PD-L1 Expression and Its Clinical Significance in Circulating Tumor Cells from Patients with Non-Small-Cell Lung Cancer.
Yuxin Cheng, Ting Wang, +7 authors, Lifeng Wang.
Cancer Manag Res, 2020 Apr 08; 12. PMID: 32256114    Free PMC article.
What is the potential use of platelet-rich-plasma (PRP) in cancer treatment? A mini review.
Angela C M Luzo, Wagner J Fávaro, Amedea B Seabra, Nelson Durán.
Heliyon, 2020 Apr 08; 6(3). PMID: 32258495    Free PMC article.
Review.
Immunotherapy: From Advanced NSCLC to Early Stages, an Evolving Concept.
Thierry Berghmans, Valérie Durieux, Lizza E L Hendriks, Anne-Marie Dingemans.
Front Med (Lausanne), 2020 Apr 09; 7. PMID: 32266275    Free PMC article.
Systematic Review.
Combining Immune Checkpoint Inhibitors with Anti-Angiogenic Agents.
Paola Ciciola, Priscilla Cascetta, +2 authors, Roberto Bianco.
J Clin Med, 2020 Mar 07; 9(3). PMID: 32138216    Free PMC article.
Review.
Dendritic Cells in Anticancer Vaccination: Rationale for Ex Vivo Loading or In Vivo Targeting.
Alexey V Baldin, Lyudmila V Savvateeva, Alexandr V Bazhin, Andrey A Zamyatnin.
Cancers (Basel), 2020 Mar 11; 12(3). PMID: 32150821    Free PMC article.
Review.
Rationale for Combining Radiotherapy and Immune Checkpoint Inhibition for Patients With Hypoxic Tumors.
Franziska Eckert, Kerstin Zwirner, +3 authors, Stephan M Huber.
Front Immunol, 2019 Apr 02; 10. PMID: 30930892    Free PMC article.
Review.
Targeting the Antibody Checkpoints to Enhance Cancer Immunotherapy-Focus on FcγRIIB.
Ingrid Teige, Linda Mårtensson, Björn L Frendéus.
Front Immunol, 2019 Apr 02; 10. PMID: 30930905    Free PMC article.
Review.
Targeting Mutated Plus Germline Epitopes Confers Pre-clinical Efficacy of an Instantly Formulated Cancer Nano-Vaccine.
Mona O Mohsen, Monique Vogel, +12 authors, Martin F Bachmann.
Front Immunol, 2019 Jun 04; 10. PMID: 31156619    Free PMC article.
Tumor-Associated Lymphatic Vessel Features and Immunomodulatory Functions.
Laure Garnier, Anastasia-Olga Gkountidi, Stephanie Hugues.
Front Immunol, 2019 Apr 27; 10. PMID: 31024552    Free PMC article.
Review.
Inflammatory Mechanisms of HCC Development.
Maria Grazia Refolo, Caterina Messa, +2 authors, Rosalba D'Alessandro.
Cancers (Basel), 2020 Mar 14; 12(3). PMID: 32164265    Free PMC article.
Review.
CD38 in Adenosinergic Pathways and Metabolic Re-programming in Human Multiple Myeloma Cells: In-tandem Insights From Basic Science to Therapy.
Alberto L Horenstein, Cristiano Bracci, Fabio Morandi, Fabio Malavasi.
Front Immunol, 2019 May 10; 10. PMID: 31068926    Free PMC article.
Review.
Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition.
Jared M Newton, Aurelie Hanoteau, +11 authors, Andrew G Sikora.
J Immunother Cancer, 2019 Aug 15; 7(1). PMID: 31409394    Free PMC article.
PD-L1 Distribution and Perspective for Cancer Immunotherapy-Blockade, Knockdown, or Inhibition.
Yilun Wu, Weiyu Chen, Zhi Ping Xu, Wenyi Gu.
Front Immunol, 2019 Sep 12; 10. PMID: 31507611    Free PMC article.
Highly Cited. Review.
New Approaches on Cancer Immunotherapy.
Jong-Ho Cha, Li-Chuan Chan, Min Sup Song, Mien-Chie Hung.
Cold Spring Harb Perspect Med, 2019 Oct 17; 10(8). PMID: 31615865    Free PMC article.
Review.
Quantitative Mechanistic Modeling in Support of Pharmacological Therapeutics Development in Immuno-Oncology.
Kirill Peskov, Ivan Azarov, +3 authors, Gabriel Helmlinger.
Front Immunol, 2019 May 28; 10. PMID: 31134058    Free PMC article.
Review.
Toward the development of true "off-the-shelf" synthetic T-cell immunotherapy.
Shoichi Iriguchi, Shin Kaneko.
Cancer Sci, 2018 Nov 30; 110(1). PMID: 30485606    Free PMC article.
Review.
Distinct chemotherapy-associated anti-cancer immunity by myeloid cells inhibition in murine pancreatic cancer models.
Yoshio Sakai, Masaki Miyazawa, +14 authors, Shuichi Kaneko.
Cancer Sci, 2019 Jan 19; 110(3). PMID: 30657234    Free PMC article.
Prognostic relevance of tertiary lymphoid organs following neoadjuvant chemoradiotherapy in pancreatic ductal adenocarcinoma.
Shota Kuwabara, Takahiro Tsuchikawa, +17 authors, Satoshi Hirano.
Cancer Sci, 2019 Apr 19; 110(6). PMID: 30997706    Free PMC article.
CIITA-Driven MHC Class II Expressing Tumor Cells as Antigen Presenting Cell Performers: Toward the Construction of an Optimal Anti-tumor Vaccine.
Roberto S Accolla, Elise Ramia, Alessandra Tedeschi, Greta Forlani.
Front Immunol, 2019 Aug 17; 10. PMID: 31417570    Free PMC article.
Review.
VISTA: Coming of age as a multi-lineage immune checkpoint.
M A ElTanbouly, E Schaafsma, R J Noelle, J L Lines.
Clin Exp Immunol, 2020 Jan 14; 200(2). PMID: 31930484    Free PMC article.
Review.
Integration of Omics Data Sources to Inform Mechanistic Modeling of Immune-Oncology Therapies: A Tutorial for Clinical Pharmacologists.
Georgia Lazarou, Vijayalakshmi Chelliah, +3 authors, Andrzej M Kierzek.
Clin Pharmacol Ther, 2020 Jan 20; 107(4). PMID: 31955413    Free PMC article.
Review.
Differential Immunomodulatory Effect of Carbon Dots Influenced by the Type of Surface Passivation Agent.
Furkan Ayaz, Melis Ozge Alas, Rukan Genc.
Inflammation, 2019 Dec 25; 43(2). PMID: 31873835
Modeling and Analyzing Stem-Cell Therapy toward Cancer: Evolutionary Game Theory Perspective.
Zahra Veisi, Heydar Khadem, Samin Ravanshadi.
Iran J Public Health, 2020 Apr 21; 49(1). PMID: 32309233    Free PMC article.
High Salt Inhibits Tumor Growth by Enhancing Anti-tumor Immunity.
Ralf Willebrand, Ibrahim Hamad, +13 authors, Markus Kleinewietfeld.
Front Immunol, 2019 Jun 20; 10. PMID: 31214164    Free PMC article.
Triple-negative breast cancer: recent treatment advances.
Alice R T Bergin, Sherene Loi.
F1000Res, 2019 Aug 27; 8. PMID: 31448088    Free PMC article.
Review.
DNT Cell-based Immunotherapy: Progress and Applications.
Yingrui Li, Kang Dong, +4 authors, Qin Li.
J Cancer, 2020 Apr 25; 11(13). PMID: 32328176    Free PMC article.
Review.
Recent Progress of Potentiating Immune Checkpoint Blockade with External Stimuli-an Industry Perspective.
Jun Xu, Robert Saklatvala, +2 authors, Adam Procopio.
Adv Sci (Weinh), 2020 Apr 25; 7(8). PMID: 32328428    Free PMC article.
Review.
Drastic healing process after pembrolizumab monotherapy in a case of advanced squamous cell carcinoma with severe bronchial stenosis observed over a two-year period using continuous bronchoscopy: A case report.
Kei Morikawa, Hirotaka Kida, +3 authors, Masamichi Mineshita.
Thorac Cancer, 2020 Mar 07; 11(5). PMID: 32142590    Free PMC article.
Induction of anti-cancer T cell immunity by in situ vaccination using systemically administered nanomedicines.
Geoffrey M Lynn, Richard Laga, Christopher M Jewell.
Cancer Lett, 2019 Jun 12; 459. PMID: 31185250    Free PMC article.
Review.
Development of a PD-L1-Expressing Orthotopic Liver Cancer Model: Implications for Immunotherapy for Hepatocellular Carcinoma.
Da-Liang Ou, Yu-Yang Lin, +7 authors, Chiun Hsu.
Liver Cancer, 2019 Jun 14; 8(3). PMID: 31192153    Free PMC article.
Safety and efficacy of PD-1/PD-L1 blockade in patients with preexisting antinuclear antibodies.
T Sakakida, T Ishikawa, +19 authors, K Takayama.
Clin Transl Oncol, 2019 Oct 03; 22(6). PMID: 31576495
The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy.
Vancheswaran Gopalakrishnan, Beth A Helmink, +2 authors, Jennifer A Wargo.
Cancer Cell, 2018 Apr 11; 33(4). PMID: 29634945    Free PMC article.
Highly Cited. Review.
Development of Tumor Cell-Based Vaccine with IL-12 Gene Electrotransfer as Adjuvant.
Tinkara Remic, Gregor Sersa, +2 authors, Urska Kamensek.
Vaccines (Basel), 2020 Mar 04; 8(1). PMID: 32121641    Free PMC article.
Tumor Targeted Nanocarriers for Immunotherapy.
Alejandro Baeza.
Molecules, 2020 Apr 01; 25(7). PMID: 32225049    Free PMC article.
Review.
Recent advances in HIV-associated Kaposi sarcoma.
Alessia Dalla Pria, David J Pinato, Margherita Bracchi, Mark Bower.
F1000Res, 2019 Jul 13; 8. PMID: 31297181    Free PMC article.
Review.
Comparison of a combination of chemotherapy and immune checkpoint inhibitors and immune checkpoint inhibitors alone for the treatment of advanced and metastatic non-small cell lung cancer.
Chih-Hsi Scott Kuo, Chin-Chou Wang, +8 authors, Cheng-Ta Yang.
Thorac Cancer, 2019 Apr 06; 10(5). PMID: 30950239    Free PMC article.
Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source.
Wanrong Meng, Chanshi He, +3 authors, Guiquan Zhu.
Drug Deliv, 2020 Apr 09; 27(1). PMID: 32264719    Free PMC article.
Review.
Antibody targeting of B7-H4 enhances the immune response in urothelial carcinoma.
Joseph R Podojil, Alexander P Glaser, +11 authors, Joshua J Meeks.
Oncoimmunology, 2020 May 05; 9(1). PMID: 32363111    Free PMC article.
Re-irradiation for oligoprogression under Nivolumab in recurrent head and neck squamous cell carcinoma: A case report.
Pierluigi Bonomo, Sara Lucidi, +8 authors, Lorenzo Livi.
Clin Transl Radiat Oncol, 2020 May 06; 23. PMID: 32368625    Free PMC article.
Alteration in tumoural PD-L1 expression and stromal CD8-positive tumour-infiltrating lymphocytes after concurrent chemo-radiotherapy for non-small cell lung cancer.
Kazue Yoneda, Taiji Kuwata, +7 authors, Fumihiro Tanaka.
Br J Cancer, 2019 Aug 08; 121(6). PMID: 31388183    Free PMC article.
Cellular cytotoxicity is a form of immunogenic cell death.
Luna Minute, Alvaro Teijeira, +12 authors, Ignacio Melero.
J Immunother Cancer, 2020 Mar 29; 8(1). PMID: 32217765    Free PMC article.
Systemic Immune Response and Cancer Risk: Filling the Missing Piece of Immuno-Oncology.
Mingyang Song, Shelley S Tworoger.
Cancer Res, 2020 May 06; 80(9). PMID: 32366528    Free PMC article.
Check and Checkmate: Battling Cancer with Multiplex Immunotherapy.
John C Bell.
Mol Ther, 2020 Apr 19; 28(5). PMID: 32304670    Free PMC article.
Rational design of peptides for identification of linear epitopes and generation of neutralizing monoclonal antibodies against DKK2 for cancer therapy.
Rongqing Zhao, Qian Xiao, +7 authors, Le Sun.
Antib Ther, 2020 May 12; 3(2). PMID: 32391516    Free PMC article.
The predictive role of preoperative and postoperative neutrophil-lymphocyte ratio in sarcomatoid renal cell carcinoma.
Roy Mano, Jessica Flynn, +9 authors, A Ari Hakimi.
Urol Oncol, 2019 Oct 09; 37(12). PMID: 31590969    Free PMC article.
OX40 and LAG3 are associated with better prognosis in advanced gastric cancer patients treated with anti-programmed death-1 antibody.
Hirofumi Ohmura, Kyoko Yamaguchi, +15 authors, Eishi Baba.
Br J Cancer, 2020 Mar 24; 122(10). PMID: 32203221    Free PMC article.
Host deficiency in ephrin-A1 inhibits breast cancer metastasis.
Eileen Shiuan, Ashwin Inala, +4 authors, Dana M Brantley-Sieders.
F1000Res, 2020 Jun 10; 9. PMID: 32399207    Free PMC article.
A New Era in Systemic Therapy for Hepatocellular Carcinoma: Atezolizumab plus Bevacizumab Combination Therapy.
Masatoshi Kudo.
Liver Cancer, 2020 May 14; 9(2). PMID: 32399427    Free PMC article.
MR1-Restricted T Cells Are Unprecedented Cancer Fighters.
Alessandro Vacchini, Andrew Chancellor, +2 authors, Gennaro De Libero.
Front Immunol, 2020 May 16; 11. PMID: 32411144    Free PMC article.
Review.
Future Challenges in Cancer Resistance to Immunotherapy.
Marit J van Elsas, Thorbald van Hall, Sjoerd H van der Burg.
Cancers (Basel), 2020 Apr 16; 12(4). PMID: 32290124    Free PMC article.
Review.
Characterization of a Novel Murine Colon Carcinoma Subline with High-Metastatic Activity Established by In Vivo Selection Method.
Liqiu Ma, Yoshimitsu Sakamoto, +5 authors, Takashi Shimokawa.
Int J Mol Sci, 2020 Apr 25; 21(8). PMID: 32325684    Free PMC article.
Contribution of Macrophages and T Cells in Skeletal Metastasis.
Veronica Mendoza-Reinoso, Laurie K McCauley, Pierrick G J Fournier.
Cancers (Basel), 2020 Apr 25; 12(4). PMID: 32326073    Free PMC article.
Review.
Engineering nanoparticles to reprogram radiotherapy and immunotherapy: recent advances and future challenges.
Jing Jin, Qijie Zhao.
J Nanobiotechnology, 2020 May 16; 18(1). PMID: 32408880    Free PMC article.
Review.
Clinical sequelae of the novel coronavirus: does COVID-19 infection predispose patients to cancer?
Priya Hays.
Future Oncol, 2020 May 28; 16(20). PMID: 32456461    Free PMC article.
Review.
High expression of immune checkpoints is associated with the TIL load, mutation rate and patient survival in colorectal cancer.
Mara Kitsou, Georgios D Ayiomamitis, Apostolos Zaravinos.
Int J Oncol, 2020 May 30; 57(1). PMID: 32468013    Free PMC article.
Manipulating Gut Microbiota Composition to Enhance the Therapeutic Effect of Cancer Immunotherapy.
Ming Yi, Dechao Jiao, +3 authors, Kongming Wu.
Integr Cancer Ther, 2019 Sep 14; 18. PMID: 31517538    Free PMC article.
Review.
Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow.
Vaishali Kapoor, Andrea Collins, +8 authors, Dinesh Thotala.
Oncotarget, 2020 Jun 02; 11(19). PMID: 32477458    Free PMC article.
Scientific Rationale for Combination Immunotherapy of Hepatocellular Carcinoma with Anti-PD-1/PD-L1 and Anti-CTLA-4 Antibodies.
Masatoshi Kudo.
Liver Cancer, 2020 Jun 02; 8(6). PMID: 32479569    Free PMC article.
A QSP model of prostate cancer immunotherapy to identify effective combination therapies.
Roberta Coletti, Lorena Leonardelli, Silvia Parolo, Luca Marchetti.
Sci Rep, 2020 Jun 05; 10(1). PMID: 32493951    Free PMC article.
Predictive Biomarkers of Immune Checkpoint Inhibition in Gastroesophageal Cancers.
Raghav Sundar, Elizabeth C Smyth, +2 authors, Patrick Tan.
Front Oncol, 2020 Jun 06; 10. PMID: 32500029    Free PMC article.
Review.
Characterization of Hypoxia Signature to Evaluate the Tumor Immune Microenvironment and Predict Prognosis in Glioma Groups.
Wanzun Lin, Shihong Wu, +7 authors, Sufang Qiu.
Front Oncol, 2020 Jun 06; 10. PMID: 32500034    Free PMC article.
Neoadjuvant rituximab modulates the tumor immune environment in patients with high risk prostate cancer.
Stephen T Ryan, Jing Zhang, +14 authors, Christina A M Jamieson.
J Transl Med, 2020 May 30; 18(1). PMID: 32466781    Free PMC article.
Dendritic Cells and Their Role in Immunotherapy.
Alycia Gardner, Álvaro de Mingo Pulido, Brian Ruffell.
Front Immunol, 2020 Jun 09; 11. PMID: 32508825    Free PMC article.
Review.
Growth/Differentiation Factor-15 (GDF-15): From Biomarker to Novel Targetable Immune Checkpoint.
Jörg Wischhusen, Ignacio Melero, Wolf Herman Fridman.
Front Immunol, 2020 Jun 09; 11. PMID: 32508832    Free PMC article.
Review.
Friend or Foe? Recent Strategies to Target Myeloid Cells in Cancer.
Mehdi Chaib, Subhash C Chauhan, Liza Makowski.
Front Cell Dev Biol, 2020 Jun 09; 8. PMID: 32509781    Free PMC article.
Review.
Loss of myeloid-specific lamin A/C drives lung metastasis through Gfi-1 and C/EBPε-mediated granulocytic differentiation.
Hiroki Ishii, Woo-Yong Park, +6 authors, Li Yang.
Mol Carcinog, 2020 Jan 09; 59(7). PMID: 31912614    Free PMC article.
Immune Checkpoint Inhibitor-Related Myositis: From Biology to Bedside.
Antonio G Solimando, Lucilla Crudele, +5 authors, Vito Racanelli.
Int J Mol Sci, 2020 May 03; 21(9). PMID: 32357515    Free PMC article.
Review.
Engineering bionic T cells: signal 1, signal 2, signal 3, reprogramming and the removal of inhibitory mechanisms.
Iñaki Etxeberria, Irene Olivera, +4 authors, Ignacio Melero.
Cell Mol Immunol, 2020 May 21; 17(6). PMID: 32433539    Free PMC article.
Review.
Recent Advances: The Imbalance of Immune Cells and Cytokines in the Pathogenesis of Hepatocellular Carcinoma.
Kumar Jayant, Nagy Habib, +2 authors, Ramesh Arasaradnam.
Diagnostics (Basel), 2020 May 30; 10(5). PMID: 32466214    Free PMC article.
Review.
Interplay between glucocorticoids and tumor-infiltrating lymphocytes on the prognosis of adrenocortical carcinoma.
Laura-Sophie Landwehr, Barbara Altieri, +5 authors, Silviu Sbiera.
J Immunother Cancer, 2020 Jun 01; 8(1). PMID: 32474412    Free PMC article.
Immunometabolism: new insights and lessons from antigen-directed cellular immune responses.
Renata Ramalho, Martin Rao, +5 authors, Markus Maeurer.
Semin Immunopathol, 2020 Jun 11; 42(3). PMID: 32519148    Free PMC article.
Review.
Epigenetic strategies synergize with PD-L1/PD-1 targeted cancer immunotherapies to enhance antitumor responses.
Xi Chen, Xiaohui Pan, +5 authors, Ling Ding.
Acta Pharm Sin B, 2020 Jun 13; 10(5). PMID: 32528824    Free PMC article.
Review.
Supramolecular Self-Assembled Nanostructures for Cancer Immunotherapy.
Zichao Huang, Wantong Song, Xuesi Chen.
Front Chem, 2020 Jun 13; 8. PMID: 32528926    Free PMC article.
Review.
Reprograming the tumor immunologic microenvironment using neoadjuvant chemotherapy in osteosarcoma.
Chuangzhong Deng, Yanyang Xu, +11 authors, Jin Wang.
Cancer Sci, 2020 Apr 02; 111(6). PMID: 32232912    Free PMC article.
Scientific Rationale for Combined Immunotherapy with PD-1/PD-L1 Antibodies and VEGF Inhibitors in Advanced Hepatocellular Carcinoma.
Masatoshi Kudo.
Cancers (Basel), 2020 May 01; 12(5). PMID: 32349374    Free PMC article.
Review.
Acquired Resistance to Immune Checkpoint Blockade Therapies.
Xianda Zhao, Dechen Wangmo, Matthew Robertson, Subbaya Subramanian.
Cancers (Basel), 2020 May 10; 12(5). PMID: 32380703    Free PMC article.
Review.
P53: A Guardian of Immunity Becomes Its Saboteur through Mutation.
Arjelle Decasa Agupitan, Paul Neeson, +3 authors, Ygal Haupt.
Int J Mol Sci, 2020 May 18; 21(10). PMID: 32414156    Free PMC article.
Review.
Acidosis-Induced TGF-β2 Production Promotes Lipid Droplet Formation in Dendritic Cells and Alters Their Potential to Support Anti-Mesothelioma T Cell Response.
Natalia Trempolec, Charline Degavre, +3 authors, Olivier Feron.
Cancers (Basel), 2020 May 23; 12(5). PMID: 32438640    Free PMC article.
Safety, immunogenicity, and clinical efficacy of durvalumab in combination with folate receptor alpha vaccine TPIV200 in patients with advanced ovarian cancer: a phase II trial.
Dmitriy Zamarin, Sven Walderich, +16 authors, Jason A Konner.
J Immunother Cancer, 2020 Jun 07; 8(1). PMID: 32503949    Free PMC article.
Efficacy and Safety of Pembrolizumab Plus Docetaxel vs Docetaxel Alone in Patients With Previously Treated Advanced Non-Small Cell Lung Cancer: The PROLUNG Phase 2 Randomized Clinical Trial.
Oscar Arrieta, Feliciano Barrón, +12 authors, Rafael Rosell.
JAMA Oncol, 2020 Apr 10; 6(6). PMID: 32271354    Free PMC article.
Opportunities for Conventional and in Situ Cancer Vaccine Strategies and Combination with Immunotherapy for Gastrointestinal Cancers, A Review.
Rachid Bouzid, Maikel Peppelenbosch, Sonja I Buschow.
Cancers (Basel), 2020 May 06; 12(5). PMID: 32365838    Free PMC article.
Review.
Immune Checkpoint Inhibitors for Lung Cancer Treatment: A Review.
Keisuke Onoi, Yusuke Chihara, +6 authors, Koichi Takayama.
J Clin Med, 2020 May 10; 9(5). PMID: 32384677    Free PMC article.
Review.
Promising abscopal effect of combination therapy with thermal tumour ablation and intratumoural OK-432 injection in the rat osteosarcoma model.
Tadashi Iwai, Naoto Oebisu, +5 authors, Hiroaki Nakamura.
Sci Rep, 2020 Jun 17; 10(1). PMID: 32541941    Free PMC article.
Novel Nuclear Medicine Imaging Applications in Immuno-Oncology.
Stefano Frega, Alessandro Dal Maso, +4 authors, Laura Evangelista.
Cancers (Basel), 2020 May 28; 12(5). PMID: 32455666    Free PMC article.
Review.
Immune landscape of human prostate cancer: immune evasion mechanisms and biomarkers for personalized immunotherapy.
Mayassa J Bou-Dargham, Linlin Sha, Qing-Xiang Amy Sang, Jinfeng Zhang.
BMC Cancer, 2020 Jun 20; 20(1). PMID: 32552802    Free PMC article.
Gene expression of prostaglandin EP4 receptor in three canine carcinomas.
Margaret L Musser, Austin K Viall, +2 authors, Chad M Johannes.
BMC Vet Res, 2020 Jun 24; 16(1). PMID: 32571310    Free PMC article.
Intratumoral immune activation with TLR4 agonist synergizes with effector T cells to eradicate established murine tumors.
Tina C Albershardt, Jardin Leleux, +3 authors, Jan Ter Meulen.
NPJ Vaccines, 2020 Jun 25; 5(1). PMID: 32579133    Free PMC article.
The Cancer-Immune Set Point in Oesophageal Cancer.
Robert Power, Maeve A Lowery, John V Reynolds, Margaret R Dunne.
Front Oncol, 2020 Jun 26; 10. PMID: 32582553    Free PMC article.
Review.
Manipulation of Metabolic Pathways and Its Consequences for Anti-Tumor Immunity: A Clinical Perspective.
Huang-Yu Yang, Chao-Yi Wu, Jonathan D Powell, Kun-Lin Lu.
Int J Mol Sci, 2020 Jun 10; 21(11). PMID: 32512898    Free PMC article.
Review.
Superparamagnetic iron oxide nanoparticles (SPIONs) as a multifunctional tool in various cancer therapies.
Marika Musielak, Igor Piotrowski, Wiktoria M Suchorska.
Rep Pract Oncol Radiother, 2019 Jun 14; 24(4). PMID: 31193459    Free PMC article.
OX40+ plasmacytoid dendritic cells in the tumor microenvironment promote antitumor immunity.
Kate Poropatich, Donye Dominguez, +10 authors, Bin Zhang.
J Clin Invest, 2020 Mar 18; 130(7). PMID: 32182225    Free PMC article.
CD8+CD57+ T cells exhibit distinct features in human non-small cell lung cancer.
Bing Huang, Rong Liu, +8 authors, Lequn Li.
J Immunother Cancer, 2020 Jul 02; 8(1). PMID: 32606053    Free PMC article.
Cancer Epigenetics, Tumor Immunity, and Immunotherapy.
Jian Cao, Qin Yan.
Trends Cancer, 2020 Jul 02; 6(7). PMID: 32610068    Free PMC article.
Review.
The Role of Immune Checkpoint Inhibitors in the Treatment of Extensive-Stage Extrapulmonary Small Cell Carcinoma.
Ragia Aly, Sachin Gupta, Rashmika Potdar.
Cureus, 2020 Jul 04; 12(6). PMID: 32617246    Free PMC article.
Review.
Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients.
Nicolas Gonzalo Núñez, Jimena Tosello Boari, +18 authors, Eliane Piaggio.
Nat Commun, 2020 Jul 01; 11(1). PMID: 32601304    Free PMC article.
Immune Microenvironment of Thyroid Cancer.
Hongyu Yin, Yemei Tang, Yujia Guo, Shuxin Wen.
J Cancer, 2020 Jul 07; 11(16). PMID: 32626535    Free PMC article.
Review.
Presence of a 34-gene signature is a favorable prognostic marker in squamous non-small cell lung carcinoma.
W S M E Theelen, O Krijgsman, +10 authors, K Schulze.
J Transl Med, 2020 Jul 06; 18(1). PMID: 32620126    Free PMC article.
Nanoscale Metal-Organic Framework Mediates Radical Therapy to Enhance Cancer Immunotherapy.
Kaiyuan Ni, Theint Aung, +3 authors, Wenbin Lin.
Chem, 2019 Aug 07; 5(7). PMID: 31384694    Free PMC article.
Higher neutrophil-lymphocyte ratio is associated with better prognosis of hepatocellular carcinoma.
Sheng-Chao Li, Zhuo Xu, +2 authors, Yu-Ming Jia.
Medicine (Baltimore), 2020 Jul 08; 99(27). PMID: 32629689    Free PMC article.
Novel Immunotherapeutic Approaches in Head and Neck Cancer.
M E Heft Neal, C T Haring, +3 authors, P L Swiecicki.
J Cancer Metastasis Treat, 2019 Jan 01; 5. PMID: 32661502    Free PMC article.
Overcoming immunotherapeutic resistance by targeting the cancer inflammation cycle.
Max M Wattenberg, Gregory L Beatty.
Semin Cancer Biol, 2020 Jan 19; 65. PMID: 31954172    Free PMC article.
Review.
Combined PARP Inhibition and Immune Checkpoint Therapy in Solid Tumors.
Florent Peyraud, Antoine Italiano.
Cancers (Basel), 2020 Jun 13; 12(6). PMID: 32526888    Free PMC article.
Review.
Resistance to immune checkpoint inhibitors in non-small cell lung cancer: biomarkers and therapeutic strategies.
Robert J Walsh, Ross A Soo.
Ther Adv Med Oncol, 2020 Jul 17; 12. PMID: 32670423    Free PMC article.
Review.
Immunotherapy in the Treatment of Metastatic Melanoma: Current Knowledge and Future Directions.
Massimo Ralli, Andrea Botticelli, +6 authors, Antonio Greco.
J Immunol Res, 2020 Jul 17; 2020. PMID: 32671117    Free PMC article.
Review.
Novel Genetic Melanoma Vaccines Based on Induced Pluripotent Stem Cells or Melanosphere-Derived Stem-Like Cells Display High Efficacy in a Murine Tumor Rejection Model.
Agnieszka Gąbka-Buszek, Eliza Kwiatkowska-Borowczyk, +2 authors, Andrzej Mackiewicz.
Vaccines (Basel), 2020 Apr 01; 8(2). PMID: 32224883    Free PMC article.
Modeling of the immune response in the pathogenesis of solid tumors and its prognostic significance.
Łukasz Zadka, Damian J Grybowski, Piotr Dzięgiel.
Cell Oncol (Dordr), 2020 Jun 04; 43(4). PMID: 32488850    Free PMC article.
Review.
Immunological Basis of Genesis of Hepatocellular Carcinoma: Unique Challenges and Potential Opportunities through Immunomodulation.
Kumar Jayant, Nagy Habib, +3 authors, Ramesh Arasaradnam.
Vaccines (Basel), 2020 May 28; 8(2). PMID: 32456200    Free PMC article.
Review.
Modulation of Anti-Tumour Immune Responses by Probiotic Bacteria.
Georgios Aindelis, Katerina Chlichlia.
Vaccines (Basel), 2020 Jun 25; 8(2). PMID: 32575876    Free PMC article.
Review.
Recent Advances of Gold Compounds in Anticancer Immunity.
Shuang Yue, Miao Luo, Huiguo Liu, Shuang Wei.
Front Chem, 2020 Jul 23; 8. PMID: 32695747    Free PMC article.
Review.
The interplay between innate and adaptive immunity in cancer shapes the productivity of cancer immunosurveillance.
Renee B Chang, Gregory L Beatty.
J Leukoc Biol, 2020 Apr 10; 108(1). PMID: 32272502    Free PMC article.
Review.
Selectins-The Two Dr. Jekyll and Mr. Hyde Faces of Adhesion Molecules-A Review.
Igor Tvaroška, Chandrabose Selvaraj, Jaroslav Koča.
Molecules, 2020 Jun 25; 25(12). PMID: 32575485    Free PMC article.
Review.
AtezoTRIBE: a randomised phase II study of FOLFOXIRI plus bevacizumab alone or in combination with atezolizumab as initial therapy for patients with unresectable metastatic colorectal cancer.
Carlotta Antoniotti, Beatrice Borelli, +19 authors, Chiara Cremolini.
BMC Cancer, 2020 Jul 24; 20(1). PMID: 32698790    Free PMC article.
Mechanisms of the Impact of Hashimoto Thyroiditis on Papillary Thyroid Carcinoma Progression: Relationship with the Tumor Immune Microenvironment.
Oksana Sulaieva, Olena Chernenko, +7 authors, Dmytro Shapochka.
Endocrinol Metab (Seoul), 2020 Jul 04; 35(2). PMID: 32615729    Free PMC article.
The neutrophil-lymphocyte ratio has a role in predicting the effectiveness of nivolumab in Japanese patients with metastatic renal cell carcinoma: a multi-institutional retrospective study.
Naotaka Nishiyama, Megumi Hirobe, +9 authors, Hiroshi Kitamura.
BMC Urol, 2020 Jul 28; 20(1). PMID: 32711491    Free PMC article.
Nanomicelle protects the immune activation effects of Paclitaxel and sensitizes tumors to anti-PD-1 Immunotherapy.
Qianmei Yang, Gang Shi, +20 authors, Hongxin Deng.
Theranostics, 2020 Jul 30; 10(18). PMID: 32724476    Free PMC article.
Programmed death ligand-1 expression in gastrointestinal cancer: Clinical significance and future challenges.
Kohei Yamashita, Masaaki Iwatsuki, Jaffer A Ajani, Hideo Baba.
Ann Gastroenterol Surg, 2020 Jul 30; 4(4). PMID: 32724880    Free PMC article.
Review.
Intratumoral delivery of an HPV vaccine elicits a broad anti-tumor immune response that translates into a potent anti-tumor effect in a preclinical murine HPV model.
Eiichi Ishida, Jina Lee, +10 authors, Sara I Pai.
Cancer Immunol Immunother, 2019 Jun 28; 68(8). PMID: 31243491    Free PMC article.
Synergistic effects of low‑dose chemotherapy and T cells in renal cell carcinoma.
Dan-Dan Xu, Men Ding, +5 authors, Ning Li.
Oncol Rep, 2020 Jul 25; 44(3). PMID: 32705278    Free PMC article.
Advances in Molecular Mechanisms for Traditional Chinese Medicine Actions in Regulating Tumor Immune Responses.
Han Huang, Jiansong Fang, +7 authors, Xiaoqin Wu.
Front Pharmacol, 2020 Aug 01; 11. PMID: 32733246    Free PMC article.
Review.
Innate Immune Defense Mechanisms by Myeloid Cells That Hamper Cancer Immunotherapy.
Els Lebegge, Sana M Arnouk, +3 authors, Jo A Van Ginderachter.
Front Immunol, 2020 Aug 01; 11. PMID: 32733461    Free PMC article.
Review.
Nanomedicine and macroscale materials in immuno-oncology.
Qingxue Sun, Matthias Barz, +5 authors, Yang Shi.
Chem Soc Rev, 2018 Nov 23; 48(1). PMID: 30465669    Free PMC article.
Review.
Combining Nanomedicine and Immunotherapy.
Yang Shi, Twan Lammers.
Acc Chem Res, 2019 May 24; 52(6). PMID: 31120725    Free PMC article.
AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells.
Maria L Lotsberg, Katarzyna Wnuk-Lipinska, +22 authors, Agnete Svendsen Tenfjord Engelsen.
J Thorac Oncol, 2020 Feb 06; 15(6). PMID: 32018052    Free PMC article.
Analysis of MarketScan Data for Immunosuppressive Conditions and Hospitalizations for Acute Respiratory Illness, United States.
Manish Patel, Jufu Chen, +7 authors, Carrie Reed.
Emerg Infect Dis, 2020 Apr 30; 26(8). PMID: 32348234    Free PMC article.
The Effect of Antibody Fragments on CD25 Targeted Regulatory T Cell Near-Infrared Photoimmunotherapy.
Ryuhei Okada, Yasuhiro Maruoka, +5 authors, Hisataka Kobayashi.
Bioconjug Chem, 2019 Sep 10; 30(10). PMID: 31498995    Free PMC article.
Tumors Resistant to Checkpoint Inhibitors Can Become Sensitive after Treatment with Vascular Disrupting Agents.
Michael R Horsman, Thomas R Wittenborn, Patricia S Nielsen, Pernille B Elming.
Int J Mol Sci, 2020 Jul 10; 21(13). PMID: 32640548    Free PMC article.
Erythrocyte-driven immunization via biomimicry of their natural antigen-presenting function.
Anvay Ukidve, Zongmin Zhao, +6 authors, Samir Mitragotri.
Proc Natl Acad Sci U S A, 2020 Jul 16; 117(30). PMID: 32665441    Free PMC article.
Significance of tumor mutation burden combined with immune infiltrates in the progression and prognosis of ovarian cancer.
Fangfang Bi, Ying Chen, Qing Yang.
Cancer Cell Int, 2020 Aug 11; 20. PMID: 32774167    Free PMC article.
Immunotherapy in Gastrointestinal Cancers.
Melanie Güthle, Thomas Ettrich, Thomas Seufferlein.
Visc Med, 2020 Aug 11; 36(3). PMID: 32775355    Free PMC article.
Review.
Nanomedicine and Onco-Immunotherapy: From the Bench to Bedside to Biomarkers.
Vanessa Acebes-Fernández, Alicia Landeria-Viñuela, +5 authors, Manuel Fuentes.
Nanomaterials (Basel), 2020 Jul 03; 10(7). PMID: 32610601    Free PMC article.
Review.
Necroptotic-susceptible dendritic cells exhibit enhanced antitumor activities in mice.
Zhanran Zhao, Guangzhi Zhang, Yuefang Sun, Astar Winoto.
Immun Inflamm Dis, 2020 Jul 15; 8(3). PMID: 32663380    Free PMC article.
BRAF Inhibitors: Molecular Targeting and Immunomodulatory Actions.
Ilaria Proietti, Nevena Skroza, +11 authors, Concetta Potenza.
Cancers (Basel), 2020 Jul 11; 12(7). PMID: 32645969    Free PMC article.
Review.
The Immune Profile of Pituitary Adenomas and a Novel Immune Classification for Predicting Immunotherapy Responsiveness.
Zihao Wang, Xiaopeng Guo, +7 authors, Bing Xing.
J Clin Endocrinol Metab, 2020 Jul 12; 105(9). PMID: 32652004    Free PMC article.
Correlation of MET and PD-L1 Expression in Malignant Melanoma.
Kyu Young Song, Sabina Desar, +2 authors, Alessio Giubellino.
Cancers (Basel), 2020 Jul 15; 12(7). PMID: 32659961    Free PMC article.
Gas6/Axl Signaling Pathway in the Tumor Immune Microenvironment.
Mai Tanaka, Dietmar W Siemann.
Cancers (Basel), 2020 Jul 15; 12(7). PMID: 32660000    Free PMC article.
Review.
Molecular Mechanisms and Potential Therapeutic Reversal of Pancreatic Cancer-Induced Immune Evasion.
Li-Lian Gan, Ling-Wei Hii, +2 authors, Chun-Wai Mai.
Cancers (Basel), 2020 Jul 16; 12(7). PMID: 32664564    Free PMC article.
Review.
Combinatorial Immunotherapies for Metastatic Colorectal Cancer.
Eline Janssen, Beatriz Subtil, +2 authors, Daniele V F Tauriello.
Cancers (Basel), 2020 Jul 16; 12(7). PMID: 32664619    Free PMC article.
Review.
An open-label, phase II multicohort study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors.
Kirsty Taylor, Helen Loo Yau, +20 authors, Daniel D De Carvalho.
J Immunother Cancer, 2020 Aug 06; 8(2). PMID: 32753546    Free PMC article.
Genetic associations of T cell cancer immune response-related genes with T cell phenotypes and clinical outcomes of early-stage lung cancer.
Qinchuan Wang, Jianchun Gu, +5 authors, Xifeng Wu.
J Immunother Cancer, 2020 Aug 09; 8(2). PMID: 32764075    Free PMC article.
Evaluation of cytotoxic T lymphocyte-mediated anticancer response against tumor interstitium-simulating physical barriers.
Shu-Ching Chen, Po-Cheng Wu, Chiao-Yi Wang, Po-Ling Kuo.
Sci Rep, 2020 Aug 14; 10(1). PMID: 32788651    Free PMC article.
Novel Frontiers of Treatment for Advanced Gastric or Gastroesophageal Junction Cancer (GC/GEJC): Will Immunotherapy Be a Future Direction?
Rilan Bai, Naifei Chen, +4 authors, Jiuwei Cui.
Front Oncol, 2020 Aug 15; 10. PMID: 32793461    Free PMC article.
Review.
Resistance Mechanisms of Anti-PD1/PDL1 Therapy in Solid Tumors.
Qingyang Lei, Dan Wang, +2 authors, Yi Zhang.
Front Cell Dev Biol, 2020 Aug 15; 8. PMID: 32793604    Free PMC article.
Review.
A nanoscale metal organic frameworks-based vaccine synergises with PD-1 blockade to potentiate anti-tumour immunity.
Xia Li, Xiupeng Wang, Atsuo Ito, Noriko M Tsuji.
Nat Commun, 2020 Aug 02; 11(1). PMID: 32737343    Free PMC article.
Interleukin-10 Induces Expression of Neuroendocrine Markers and PDL1 in Prostate Cancer Cells.
Abrar Samiea, Jeff S J Yoon, +3 authors, Alice L-F Mui.
Prostate Cancer, 2020 Aug 18; 2020. PMID: 32802517    Free PMC article.
[18F]FDG PET immunotherapy radiomics signature (iRADIOMICS) predicts response of non-small-cell lung cancer patients treated with pembrolizumab.
Damijan Valentinuzzi, Martina Vrankar, +9 authors, Robert Jeraj.
Radiol Oncol, 2020 Jul 30; 54(3). PMID: 32726293    Free PMC article.
Past, Present, and Future of Anticancer Nanomedicine.
Kyungeun Kim, Dongwoo Khang.
Int J Nanomedicine, 2020 Aug 22; 15. PMID: 32821098    Free PMC article.
Review.
Exploiting the Complexities of Glioblastoma Stem Cells: Insights for Cancer Initiation and Therapeutic Targeting.
Joana Vieira de Castro, Céline S Gonçalves, Adília Hormigo, Bruno M Costa.
Int J Mol Sci, 2020 Jul 30; 21(15). PMID: 32722427    Free PMC article.
Review.
Sequential PDT and PTT Using Dual-Modal Single-Walled Carbon Nanohorns Synergistically Promote Systemic Immune Responses against Tumor Metastasis and Relapse.
Jingxing Yang, Mengfei Hou, +10 authors, Chunfu Zhang.
Adv Sci (Weinh), 2020 Aug 25; 7(16). PMID: 32832363    Free PMC article.
Ultrathin metal-organic layer-mediated radiotherapy-radiodynamic therapy enhances immunotherapy of metastatic cancers.
Kaiyuan Ni, Guangxu Lan, +5 authors, Wenbin Lin.
Matter, 2020 Aug 25; 1(5). PMID: 32832885    Free PMC article.
KRAS as a druggable target in NSCLC: Rising like a phoenix after decades of development failures.
Alex Friedlaender, Alexander Drilon, +2 authors, Alfredo Addeo.
Cancer Treat Rev, 2020 Feb 18; 85. PMID: 32062493    Free PMC article.
Review.
New tools to prevent cancer growth and spread: a 'Clever' approach.
Maija Hollmén, Carlos R Figueiredo, Sirpa Jalkanen.
Br J Cancer, 2020 Jul 01; 123(4). PMID: 32595212    Free PMC article.
Review.
T-Cell Immunity in Pancreatic Cancer.
Reham Ajina, Louis M Weiner.
Pancreas, 2020 Aug 25; 49(8). PMID: 32833941    Free PMC article.
Review.
Absolute Counts of Peripheral Lymphocyte Subsets Correlate with the Progression-Free Survival and Metastatic Status of Pancreatic Neuroendocrine Tumour Patients.
Yitao Gong, Zhiyao Fan, +7 authors, Chen Liu.
Cancer Manag Res, 2020 Aug 28; 12. PMID: 32848455    Free PMC article.
An Immunogram for an Individualized Assessment of the Antitumor Immune Response in Patients With Hepatocellular Carcinoma.
Ying Hu, Huaibo Sun, Henghui Zhang, Xianbo Wang.
Front Oncol, 2020 Aug 28; 10. PMID: 32850343    Free PMC article.
FIR: Efficacy, Safety, and Biomarker Analysis of a Phase II Open-Label Study of Atezolizumab in PD-L1-Selected Patients With NSCLC.
David R Spigel, Jamie E Chaft, +11 authors, Naiyer A Rizvi.
J Thorac Oncol, 2018 May 19; 13(11). PMID: 29775807    Free PMC article.
Comprehensive elaboration of the cGAS-STING signaling axis in cancer development and immunotherapy.
Juyan Zheng, Junluan Mo, +7 authors, Zhaoqian Liu.
Mol Cancer, 2020 Aug 29; 19(1). PMID: 32854711    Free PMC article.
Review.
[Progress on PD-1/PD-L1 Checkpoint Inhibitors in Lung Cancer].
Di Zhang, Jiaqi Huang, +2 authors, Qisen Guo.
Zhongguo Fei Ai Za Zhi, 2019 Jun 15; 22(6). PMID: 31196371    Free PMC article.
Review.
Inhibition of protein phosphatase-2A with LB-100 enhances antitumor immunity against glioblastoma.
Dominic Maggio, Winson S Ho, +8 authors, Zhengping Zhuang.
J Neurooncol, 2020 Apr 29; 148(2). PMID: 32342332    Free PMC article.
Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy.
Jing Gao, Wei-Qi Wang, +2 authors, Hai-Jun Yu.
Acta Pharmacol Sin, 2020 Apr 23; 41(7). PMID: 32317755    Free PMC article.
Review.
Cancer nanomedicine meets immunotherapy: opportunities and challenges.
Qingxue Sun, Xiangyang Bai, +9 authors, Yang Shi.
Acta Pharmacol Sin, 2020 Jun 20; 41(7). PMID: 32555445    Free PMC article.
Review.
Early Change in the Plasma Levels of Circulating Soluble Immune Checkpoint Proteins in Patients with Unresectable Hepatocellular Carcinoma Treated by Lenvatinib or Transcatheter Arterial Chemoembolization.
Naoshi Odagiri, Hoang Hai, +8 authors, Norifumi Kawada.
Cancers (Basel), 2020 Jul 30; 12(8). PMID: 32722224    Free PMC article.
Understanding the Role of Innate Immune Cells and Identifying Genes in Breast Cancer Microenvironment.
Israa Shihab, Bariaa A Khalil, +4 authors, Azzam A Maghazachi.
Cancers (Basel), 2020 Aug 14; 12(8). PMID: 32784928    Free PMC article.
Review.
Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity.
Sandra Grund-Gröschke, Daniela Ortner, +11 authors, Fritz Aberger.
Mol Oncol, 2020 Jul 03; 14(9). PMID: 32615027    Free PMC article.
Atezolizumab in combination with carboplatin and etoposide for heavily treated small cell lung cancer.
Nobutaka Kataoka, Yusuke Kunimatsu, +6 authors, Takayuki Takeda.
Thorac Cancer, 2020 Jul 25; 11(9). PMID: 32706170    Free PMC article.
Myeloid Cells Orchestrate Systemic Immunosuppression, Impairing the Efficacy of Immunotherapy against HPV+ Cancers.
Gabriele Galliverti, Stephan Wullschleger, +7 authors, Douglas Hanahan.
Cancer Immunol Res, 2019 Nov 28; 8(1). PMID: 31771984    Free PMC article.
The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them.
Martyn T Smith, Kathryn Z Guyton, +20 authors, Mark Fielden.
Cancer Epidemiol Biomarkers Prev, 2020 Mar 11; 29(10). PMID: 32152214    Free PMC article.
IFN-γ treatment protocol for MHC-Ilo/PD-L1+ pancreatic tumor cells selectively restores their TAP-mediated presentation competence and CD8 T-cell priming potential.
Katja Stifter, Jana Krieger, +7 authors, Reinhold Schirmbeck.
J Immunother Cancer, 2020 Sep 02; 8(2). PMID: 32868392    Free PMC article.
pH-Responsive Nanoparticles for Cancer Immunotherapy: A Brief Review.
Yunfeng Yan, Hangwei Ding.
Nanomaterials (Basel), 2020 Aug 23; 10(8). PMID: 32824578    Free PMC article.
Review.
Modulating barriers of tumor microenvironment through nanocarrier systems for improved cancer immunotherapy: a review of current status and future perspective.
Huanrong Lan, Wei Zhang, +2 authors, Zhen Wang.
Drug Deliv, 2020 Sep 01; 27(1). PMID: 32865029    Free PMC article.
Review.
A Novel Epitope Quality-Based Immune Escape Mechanism Reveals Patient's Suitability for Immune Checkpoint Inhibition.
Michael Wessolly, Susann Stephan-Falkenau, +12 authors, Fabian D Mairinger.
Cancer Manag Res, 2020 Sep 15; 12. PMID: 32922086    Free PMC article.
IFNγ and TNFα synergistically promote galectin 9 secretion by human osteosarcoma cells MG-63 to prevent T cell killing.
Yuchang Liu, Junzhong Luo, +2 authors, Xuan Wang.
Int J Clin Exp Pathol, 2020 Sep 15; 13(8). PMID: 32922595    Free PMC article.
Identification of a neo-epitope dominating endogenous CD8 T cell responses to MC-38 colorectal cancer.
Brett J Hos, Marcel G M Camps, +11 authors, Ferry Ossendorp.
Oncoimmunology, 2020 Sep 15; 9(1). PMID: 32923109    Free PMC article.
Outlook: Immunotherapy in Gastrointestinal Carcinoma - Innovative Strategies.
Markus Moehler, Katrin Göpfert, Heinz-Josef Lenz.
Oncol Res Treat, 2018 May 01; 41(5). PMID: 29705792    Free PMC article.
Review.
IL15 synergizes with radiotherapy to reprogram the tumor immune contexture through a dendritic cell connection.
Karsten A Pilones, Maud Charpentier, Elena Garcia-Martinez, Sandra Demaria.
Oncoimmunology, 2020 Sep 17; 9(1). PMID: 32934886    Free PMC article.
Review.
Current state and future of co-inhibitory immune checkpoints for the treatment of glioblastoma.
Shaoping Shen, Ling Chen, +8 authors, Tianyi Liu.
Cancer Biol Med, 2020 Sep 19; 17(3). PMID: 32944390    Free PMC article.
Review.
Immunotherapy in prostate cancer: current state and future perspectives.
Shivani Handa, Bandhul Hans, +3 authors, Ashutosh Tewari.
Ther Adv Urol, 2020 Sep 22; 12. PMID: 32952615    Free PMC article.
Review.
Targeted Co-delivery of Tumor Antigen and α-Galactosylceramide to CD141+ Dendritic Cells Induces a Potent Tumor Antigen-Specific Human CD8+ T Cell Response in Human Immune System Mice.
Jing Huang, Jing Zhou, +9 authors, Moriya Tsuji.
Front Immunol, 2020 Sep 26; 11. PMID: 32973811    Free PMC article.
Biologically Inspired Design of Nanoparticle Artificial Antigen-Presenting Cells for Immunomodulation.
John W Hickey, Fernando P Vicente, +2 authors, Jonathan P Schneck.
Nano Lett, 2017 Oct 11; 17(11). PMID: 28994285    Free PMC article.
Dissecting the Immune Landscape of Acute Myeloid Leukemia.
Jan Davidson-Moncada, Elena Viboch, +2 authors, Sergio Rutella.
Biomedicines, 2018 Nov 28; 6(4). PMID: 30477280    Free PMC article.
Review.
Exosomes in cancer therapy: a novel experimental strategy.
Dong Gao, Lingling Jiang.
Am J Cancer Res, 2018 Dec 18; 8(11). PMID: 30555736    Free PMC article.
Review.
Immunotherapy and pancreatic cancer: unique challenges and potential opportunities.
Kate Young, Daniel J Hughes, David Cunningham, Naureen Starling.
Ther Adv Med Oncol, 2018 Dec 24; 10. PMID: 30574212    Free PMC article.
Review.
Photothermal Ablation of Cancer Cells by Albumin-Modified Gold Nanorods and Activation of Dendritic Cells.
Xiuhui Wang, Jingchao Li, Naoki Kawazoe, Guoping Chen.
Materials (Basel), 2018 Dec 26; 12(1). PMID: 30583459    Free PMC article.
"Comparison of the toxicity profile of PD-1 versus PD-L1 inhibitors in non-small cell lung cancer": is there a substantial difference or not?
Alessia Spagnuolo, Cesare Gridelli.
J Thorac Dis, 2019 Jan 12; 10(Suppl 33). PMID: 30631556    Free PMC article.
Cytokines, Chemokines, and Other Biomarkers of Response for Checkpoint Inhibitor Therapy in Skin Cancer.
Jennifer A Bridge, James C Lee, +2 authors, Jeffrey A Bluestone.
Front Med (Lausanne), 2019 Jan 12; 5. PMID: 30631766    Free PMC article.
Review.
The role of gut microbiota in immune checkpoint inhibitor therapy.
Ming Yi, Shuang Qin, Qian Chu, Kongming Wu.
Hepatobiliary Surg Nutr, 2019 Jan 18; 7(6). PMID: 30652094    Free PMC article.
Incidence of Ipilimumab-Related Serious Adverse Events in Patients with Advanced Cancer: A Meta-Analysis.
Chang-Ying Guo, Si-Cong Jiang, Yu-Kang Kuang, Hao Hu.
J Cancer, 2019 Jan 22; 10(1). PMID: 30662532    Free PMC article.
The promise of immunotherapy in genitourinary malignancies.
Tian Zhang, Andrew J Armstrong, Daniel J George, Jiaoti Huang.
Precis Clin Med, 2019 Jan 29; 1(3). PMID: 30687563    Free PMC article.
Severe toxicity from checkpoint protein inhibitors: What intensive care physicians need to know?
Virginie Lemiale, Anne-Pascale Meert, +5 authors, Groupe de Recherche en Reanimation Respiratoire du patient d’Onco-Hématologie (Grrr-OH).
Ann Intensive Care, 2019 Feb 02; 9(1). PMID: 30707321    Free PMC article.
Review.
Batf3+ DCs and type I IFN are critical for the efficacy of neoadjuvant cancer immunotherapy.
Jing Liu, Elisa A Rozeman, +5 authors, Michele W L Teng.
Oncoimmunology, 2019 Feb 05; 8(2). PMID: 30713806    Free PMC article.
CIITA-related block of HLA class II expression, upregulation of HLA class I, and heterogeneous expression of immune checkpoints in hepatocarcinomas: implications for new therapeutic approaches.
Elise Ramia, Anna Maria Chiaravalli, +4 authors, Greta Forlani.
Oncoimmunology, 2019 Feb 07; 8(3). PMID: 30723578    Free PMC article.
Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model.
Jose M Ayuso, Regan Truttschel, +10 authors, Melissa C Skala.
Oncoimmunology, 2019 Feb 07; 8(3). PMID: 30723584    Free PMC article.
Cardiac Complications in Immune Checkpoint Inhibition Therapy.
Kazuko Tajiri, Masaki Ieda.
Front Cardiovasc Med, 2019 Feb 08; 6. PMID: 30729114    Free PMC article.
Review.
Immunotherapy in extensive small cell lung cancer.
Vaibhav Verma, Geeti Sharma, Abhijai Singh.
Exp Hematol Oncol, 2019 Feb 12; 8. PMID: 30740266    Free PMC article.
Review.
Activation of CD8⁺ T Cell Responses after Melanoma Antigen Targeting to CD169⁺ Antigen Presenting Cells in Mice and Humans.
Dieke van Dinther, Miguel Lopez Venegas, +8 authors, Joke M M den Haan.
Cancers (Basel), 2019 Feb 16; 11(2). PMID: 30764534    Free PMC article.
Dexamethasone inhibits the proliferation of tumor cells.
Yuantao Wu, Rui Xia, +6 authors, Qiang Huang.
Cancer Manag Res, 2019 Feb 19; 11. PMID: 30774442    Free PMC article.
Combination Cancer Immunotherapy with Molecular Targeted Agents/Anti-CTLA-4 Antibody for Hepatocellular Carcinoma.
Masatoshi Kudo.
Liver Cancer, 2019 Mar 01; 8(1). PMID: 30815391    Free PMC article.
Combining Radiation and Immune Checkpoint Blockade in the Treatment of Head and Neck Squamous Cell Carcinoma.
Gregor Manukian, Voichita Bar-Ad, +2 authors, Jennifer M Johnson.
Front Oncol, 2019 Mar 22; 9. PMID: 30895168    Free PMC article.
Review.
Compound-therapy based on cancer-immunity cycle: promising prospects for antitumor regimens.
Dong Gao.
Am J Cancer Res, 2019 Mar 25; 9(2). PMID: 30906623    Free PMC article.
Review.
Multiparametric analysis of CD8+ T cell compartment phenotype in chronic lymphocytic leukemia reveals a signature associated with progression toward therapy.
Pauline Gonnord, Manon Costa, +4 authors, Salvatore Valitutti.
Oncoimmunology, 2019 Mar 25; 8(4). PMID: 30906665    Free PMC article.
Emerging Nano-/Microapproaches for Cancer Immunotherapy.
Yu Mi, C Tilden Hagan, Benjamin G Vincent, Andrew Z Wang.
Adv Sci (Weinh), 2019 Apr 03; 6(6). PMID: 30937265    Free PMC article.
Review.
Non-Thermal Plasma as a Unique Delivery System of Short-Lived Reactive Oxygen and Nitrogen Species for Immunogenic Cell Death in Melanoma Cells.
Abraham Lin, Yury Gorbanev, +7 authors, Annemie Bogaerts.
Adv Sci (Weinh), 2019 Apr 03; 6(6). PMID: 30937272    Free PMC article.
Highly Cited.
Extracellular Vesicle-Based Therapeutic Targeting of β-Catenin to Modulate Anticancer Immune Responses in Hepatocellular Cancer.
Akiko Matsuda, Kaori Ishiguro, Irene K Yan, Tushar Patel.
Hepatol Commun, 2019 Apr 13; 3(4). PMID: 30976743    Free PMC article.
Enhancing Dendritic Cell Therapy in Solid Tumors with Immunomodulating Conventional Treatment.
Robert A Belderbos, Joachim G J V Aerts, Heleen Vroman.
Mol Ther Oncolytics, 2019 Apr 26; 13. PMID: 31020037    Free PMC article.
Review.
Heterogeneity of the Head and Neck Squamous Cell Carcinoma Immune Landscape and Its Impact on Immunotherapy.
Madison Canning, Gang Guo, +4 authors, Yan Cui.
Front Cell Dev Biol, 2019 Apr 27; 7. PMID: 31024913    Free PMC article.
Highly Cited. Review.
Immunogenic Cell Death and Immunotherapy of Multiple Myeloma.
Alfonso Serrano-Del Valle, Alberto Anel, Javier Naval, Isabel Marzo.
Front Cell Dev Biol, 2019 May 02; 7. PMID: 31041312    Free PMC article.
Highly Cited. Review.
Reduced Number of Lymphocytes by X-ray Irradiation: A Problem in a Combination Therapy Trial that Elicits the Abscopal Effect in Preclinical Studies Using Electron Beam Irradiation.
Shiro Kanegasaki, Takashi Yamashita, Tomoko Tsuchiya.
Cureus, 2019 May 07; 11(2). PMID: 31058025    Free PMC article.
Review.
Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models.
Adrienne Rothschilds, Alice Tzeng, +3 authors, K Dane Wittrup.
Oncoimmunology, 2019 May 10; 8(5). PMID: 31069130    Free PMC article.
The emerging links between chromosomal instability (CIN), metastasis, inflammation and tumour immunity.
Andréa E Tijhuis, Sarah C Johnson, Sarah E McClelland.
Mol Cytogenet, 2019 May 23; 12. PMID: 31114634    Free PMC article.
Review.
Cardiotoxicity of Immune Checkpoint Inhibitors.
Lili Zhang, Maeve Jones-O'Connor, +6 authors, Tomas G Neilan.
Curr Treat Options Cardiovasc Med, 2019 Jun 09; 21(7). PMID: 31175469
Review.
Hematologic markers of distant metastases in gastric cancer.
Osama Abu-Shawer, Mohammad Abu-Shawer, +9 authors, Maysa Al-Hussaini.
J Gastrointest Oncol, 2019 Jun 12; 10(3). PMID: 31183204    Free PMC article.
Liquid biopsy for lung cancer immunotherapy.
Liang-Liang Cai, Jie Wang.
Oncol Lett, 2019 Jun 13; 17(6). PMID: 31186680    Free PMC article.
Review.
The 6th R of Radiobiology: Reactivation of Anti-Tumor Immune Response.
Jihane Boustani, Mathieu Grapin, +2 authors, Céline Mirjolet.
Cancers (Basel), 2019 Jun 23; 11(6). PMID: 31226866    Free PMC article.
Review.
Can Dendritic Cell Vaccination Prevent Leukemia Relapse?
Liam J O'Brien, Camille Guillerey, Kristen J Radford.
Cancers (Basel), 2019 Jun 27; 11(6). PMID: 31234526    Free PMC article.
Review.
Targeting the Tumor Microenvironment in Renal Cell Cancer Biology and Therapy.
Isabel Heidegger, Andreas Pircher, Renate Pichler.
Front Oncol, 2019 Jul 02; 9. PMID: 31259150    Free PMC article.
Review.
Is the Blood an Alternative for Programmed Cell Death Ligand 1 Assessment in Non-Small Cell Lung Cancer?
Emmanuel Acheampong, Isaac Spencer, +3 authors, Elin Gray.
Cancers (Basel), 2019 Jul 03; 11(7). PMID: 31262041    Free PMC article.
Review.
Human Tumor-Infiltrating Dendritic Cells: From in Situ Visualization to High-Dimensional Analyses.
Margaux Hubert, Elisa Gobbini, +2 authors, Jenny Valladeau-Guilemond.
Cancers (Basel), 2019 Aug 02; 11(8). PMID: 31366174    Free PMC article.
Review.
Neutralizing monoclonal antibody against Dickkopf2 impairs lung cancer progression via activating NK cells.
Tianli Shen, Zhengxi Chen, +2 authors, Qian Xiao.
Cell Death Discov, 2019 Aug 03; 5. PMID: 31372243    Free PMC article.
Apolipoprotein A-I (ApoA-I), Immunity, Inflammation and Cancer.
Konstantina Georgila, Dimitra Vyrla, Elias Drakos.
Cancers (Basel), 2019 Aug 04; 11(8). PMID: 31374929    Free PMC article.
Review.
Mucosal Vaccination via the Respiratory Tract.
Marie Hellfritzsch, Regina Scherließ.
Pharmaceutics, 2019 Aug 04; 11(8). PMID: 31374959    Free PMC article.
Review.
Role of the Exosome in Ovarian Cancer Progression and Its Potential as a Therapeutic Target.
Koji Nakamura, Kenjiro Sawada, +5 authors, Tadashi Kimura.
Cancers (Basel), 2019 Aug 14; 11(8). PMID: 31405096    Free PMC article.
Review.
Profiling of Target Molecules for Immunotherapy in Mesenchymal Tumors.
Takuma Hayashi, Tomoyuki Ichimura, +6 authors, Ikuo Konishi.
J Clin Med Res, 2019 Aug 16; 11(8). PMID: 31413773    Free PMC article.
Achievements and futures of immune checkpoint inhibitors in non-small cell lung cancer.
Zhenbin Qiu, Zihao Chen, Chao Zhang, Wenzhao Zhong.
Exp Hematol Oncol, 2019 Aug 30; 8. PMID: 31463163    Free PMC article.
Review.
The role and therapeutic implications of T cells in cancer of the lung.
Samuel C Neeve, Bruce Ws Robinson, Vanessa S Fear.
Clin Transl Immunology, 2019 Sep 06; 8(8). PMID: 31485330    Free PMC article.
LAG-3 expression on tumor-infiltrating T cells in soft tissue sarcoma correlates with poor survival.
Yi Que, Zhixin Fang, +8 authors, Xing Zhang.
Cancer Biol Med, 2019 Sep 14; 16(2). PMID: 31516753    Free PMC article.
Down Regulation of c-FLIPL Enhance PD-1 Blockade Efficacy in B16 Melanoma.
Yao Wang, Jing-Jing Li, +5 authors, Xiao-Shi Zhang.
Front Oncol, 2019 Sep 26; 9. PMID: 31552181    Free PMC article.
Tissue Site and the Cancer Immunity Cycle.
Brendan L Horton, Tim B Fessenden, Stefani Spranger.
Trends Cancer, 2019 Nov 11; 5(10). PMID: 31706507    Free PMC article.
Review.
Phase 1 study of epacadostat in combination with atezolizumab for patients with previously treated advanced nonsmall cell lung cancer.
Matthew D Hellmann, Scott Gettinger, +8 authors, Rebecca S Heist.
Int J Cancer, 2020 Mar 07; 147(7). PMID: 32141617    Free PMC article.
Quantitative Translation in Immuno-Oncology Research and Development.
Dean Bottino, Rachael Liu, Hojjat Bazzazi, Karthik Venkatakrishnan.
Clin Pharmacol Ther, 2020 Jul 10; 108(3). PMID: 32645203    Free PMC article.
Extracellular Vesicles in the Development of Cancer Therapeutics.
Haoyao Sun, Stephanie Burrola, Jinchang Wu, Wei-Qun Ding.
Int J Mol Sci, 2020 Aug 28; 21(17). PMID: 32847103    Free PMC article.
Review.
Interaction between Immunotherapy and Antiangiogenic Therapy for Cancer.
Koichi Furukawa, Tatsuya Nagano, +2 authors, Yoshihiro Nishimura.
Molecules, 2020 Aug 30; 25(17). PMID: 32859106    Free PMC article.
Review.
A perspective on HPK1 as a novel immuno-oncology drug target.
Sansana Sawasdikosol, Steven Burakoff.
Elife, 2020 Sep 09; 9. PMID: 32896273    Free PMC article.
Review.
Evolution of drug delivery system from viewpoint of controlled intracellular trafficking and selective tissue targeting toward future nanomedicine.
Yuma Yamada, Yusuke Sato, Takashi Nakamura, Hideyoshi Harashima.
J Control Release, 2020 Sep 12; 327. PMID: 32916227    Free PMC article.
Review.
From tobacco smoking to cancer mutational signature: a mediation analysis strategy to explore the role of epigenetic changes.
Zhishan Chen, Wanqing Wen, +6 authors, Xingyi Guo.
BMC Cancer, 2020 Sep 16; 20(1). PMID: 32928150    Free PMC article.
Neoantigen-specific CD4+ T-cell response is critical for the therapeutic efficacy of cryo-thermal therapy.
Peng Peng, Hongming Hu, Ping Liu, Lisa X Xu.
J Immunother Cancer, 2020 Sep 18; 8(2). PMID: 32938627    Free PMC article.
Anti-angiogenic Agents in Combination With Immune Checkpoint Inhibitors: A Promising Strategy for Cancer Treatment.
Yuxiao Song, Yang Fu, +3 authors, Bicheng Zhang.
Front Immunol, 2020 Sep 29; 11. PMID: 32983126    Free PMC article.
Review.
Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90.
Anne Ernst, Roman Hennel, +13 authors, Kirsten Lauber.
Front Oncol, 2020 Sep 29; 10. PMID: 32984042    Free PMC article.
Characterization of a single chain variable fragment of nivolumab that targets PD-1 and blocks PD-L1 binding.
Jong Shin, Paul J Phelan, +2 authors, Peter A Bullock.
Protein Expr Purif, 2020 Sep 29; 177. PMID: 32987122    Free PMC article.
Intratumoural immunotherapies for unresectable and metastatic melanoma: current status and future perspectives.
Mark R Middleton, Christoph Hoeller, +4 authors, Axel Hauschild.
Br J Cancer, 2020 Jul 28; 123(6). PMID: 32713938    Free PMC article.
Review.
The non-linearity of RAF-MEK signaling in dendritic cells.
Kristina Riegel, Krishnaraj Rajalingam.
Cell Cycle, 2020 Aug 06; 19(18). PMID: 32752922    Free PMC article.
Review.
Cancer Cell Coating Nanoparticles for Optimal Tumor-Specific Cytokine Delivery.
Antonio E Barberio, Sean G Smith, +7 authors, Paula T Hammond.
ACS Nano, 2020 Jul 22; 14(9). PMID: 32692155    Free PMC article.
Impact of inflammation and immunotherapy in renal cell carcinoma.
Jian Shi, Keshan Wang, +10 authors, Xiaoping Zhang.
Oncol Lett, 2020 Oct 06; 20(5). PMID: 33014151    Free PMC article.
Review.
Immune-Related Adverse Events and Corticosteroid Use for Cancer-Related Symptoms Are Associated With Efficacy in Patients With Non-small Cell Lung Cancer Receiving Anti-PD-(L)1 Blockade Agents.
Mariona Riudavets, Joaquin Mosquera, +9 authors, Margarita Majem.
Front Oncol, 2020 Oct 06; 10. PMID: 33014837    Free PMC article.
PD-L1 on dendritic cells attenuates T cell activation and regulates response to immune checkpoint blockade.
Qi Peng, Xiangyan Qiu, +8 authors, Haidong Tang.
Nat Commun, 2020 Sep 26; 11(1). PMID: 32973173    Free PMC article.
Regulation of tumor growth by leukocyte-specific protein 1 in T cells.
Riri Kwon, Bong-Ki Hong, +5 authors, Wan-Uk Kim.
J Immunother Cancer, 2020 Oct 07; 8(2). PMID: 33020243    Free PMC article.
Impact of anatomic site on antigen-presenting cells in cancer.
Maria Zagorulya, Ellen Duong, Stefani Spranger.
J Immunother Cancer, 2020 Oct 07; 8(2). PMID: 33020244    Free PMC article.
Review.
Interleukin-35 promotes progression of prostate cancer and inhibits anti-tumour immunity.
Jialin Zhu, Yan Wang, +3 authors, Xueling Yang.
Cancer Cell Int, 2020 Oct 13; 20. PMID: 33041668    Free PMC article.
Targeting the immune milieu in gastrointestinal cancers.
Fiona Turkes, Justin Mencel, Naureen Starling.
J Gastroenterol, 2020 Aug 05; 55(10). PMID: 32748171    Free PMC article.
Review.
Radiogenomics for predicting p53 status, PD-L1 expression, and prognosis with machine learning in pancreatic cancer.
Yosuke Iwatate, Isamu Hoshino, +8 authors, Wataru Takayama.
Br J Cancer, 2020 Jul 22; 123(8). PMID: 32690867    Free PMC article.
The Role of Ras-Associated Protein 1 (Rap1) in Cancer: Bad Actor or Good Player?
Chin-King Looi, Ling-Wei Hii, +2 authors, Chun-Wai Mai.
Biomedicines, 2020 Sep 11; 8(9). PMID: 32906721    Free PMC article.
Review.
CD8 T Cell Score as a Prognostic Biomarker for Triple Negative Breast Cancer.
Masanori Oshi, Mariko Asaoka, +5 authors, Kazuaki Takabe.
Int J Mol Sci, 2020 Sep 26; 21(18). PMID: 32971948    Free PMC article.
Anti-SOX1 Antibodies in Paraneoplastic Neurological Syndrome.
Xuan Sun, Jiping Tan, +4 authors, Zhenfu Wang.
J Clin Neurol, 2020 Oct 09; 16(4). PMID: 33029958    Free PMC article.
Review.
COVID-19 and Cancer: Current Challenges and Perspectives.
Ziad Bakouny, Jessica E Hawley, +4 authors, Corrie A Painter.
Cancer Cell, 2020 Oct 14; 38(5). PMID: 33049215    Free PMC article.
Review.
Management of Immune Checkpoint Inhibitor Toxicities.
Quentin Durrechou, Charlotte Domblides, +5 authors, Amaury Daste.
Cancer Manag Res, 2020 Oct 17; 12. PMID: 33061607    Free PMC article.
Review.
Combination therapy: Future directions of immunotherapy in small cell lung cancer.
Wei Huang, Jia-Jia Chen, Rui Xing, Yue-Can Zeng.
Transl Oncol, 2020 Oct 17; 14(1). PMID: 33065386    Free PMC article.
Review.
Rova-T enhances the anti-tumor activity of anti-PD1 in a murine model of small cell lung cancer with endogenous Dll3 expression.
Philip Vitorino, Chen-Hua Chuang, +7 authors, Laura R Saunders.
Transl Oncol, 2020 Oct 20; 14(1). PMID: 33074129    Free PMC article.
Baseline IFN-γ and IL-10 expression in PBMCs could predict response to PD-1 checkpoint inhibitors in advanced melanoma patients.
Emilio Francesco Giunta, Giusi Barra, +11 authors, Teresa Troiani.
Sci Rep, 2020 Oct 21; 10(1). PMID: 33077770    Free PMC article.
Ferroptosis: a new unexpected chance to treat metastatic melanoma?
Mara Gagliardi, Valentina Saverio, +3 authors, Marco Corazzari.
Cell Cycle, 2020 Aug 21; 19(19). PMID: 32816618    Free PMC article.
Review.
A Tumor-Immune Interaction Model for Synergistic Combinations of Anti PD-L1 and Ionizing Irradiation Treatment.
Jong Hyuk Byun, In-Soo Yoon, +2 authors, Il Hyo Jung.
Pharmaceutics, 2020 Sep 04; 12(9). PMID: 32878065    Free PMC article.
Cellular Uptake of siRNA-Loaded Nanocarriers to Knockdown PD-L1: Strategies to Improve T-cell Functions.
Raweewan Thiramanas, Mengyi Li, +2 authors, Volker Mailänder.
Cells, 2020 Sep 11; 9(9). PMID: 32906726    Free PMC article.
Leveraging Endogenous Dendritic Cells to Enhance the Therapeutic Efficacy of Adoptive T-Cell Therapy and Checkpoint Blockade.
Mie Linder Hübbe, Ditte Elisabeth Jæhger, Thomas Lars Andresen, Mads Hald Andersen.
Front Immunol, 2020 Oct 27; 11. PMID: 33101304    Free PMC article.
Review.
Integrative immunogenomic analysis of gastric cancer dictates novel immunological classification and the functional status of tumor-infiltrating cells.
Yasuyoshi Sato, Ikuo Wada, +17 authors, Kazuhiro Kakimi.
Clin Transl Immunology, 2020 Oct 27; 9(10). PMID: 33101677    Free PMC article.
RNA-electroporated T cells for cancer immunotherapy.
Fernanda Pohl-Guimarães, Lan B Hoang-Minh, Duane A Mitchell.
Oncoimmunology, 2020 Oct 27; 9(1). PMID: 33101771    Free PMC article.
Review.
Prognostic Significance of Interferon-γ and Its Signaling Pathway in Early Breast Cancer Depends on the Molecular Subtypes.
Anne-Sophie Heimes, Franziska Härtner, +10 authors, Marcus Schmidt.
Int J Mol Sci, 2020 Oct 03; 21(19). PMID: 33003293    Free PMC article.
Intra-hepatic Abscopal Effect Following Radioembolization of Hepatic Metastases.
Maciej Powerski, Ralph Drewes, +3 authors, Maciej Pech.
Cardiovasc Intervent Radiol, 2020 Aug 19; 43(11). PMID: 32808201    Free PMC article.
Cancer-Associated Fibroblast Mediated Inhibition of CD8+ Cytotoxic T Cell Accumulation in Tumours: Mechanisms and Therapeutic Opportunities.
Patrick Freeman, Ainhoa Mielgo.
Cancers (Basel), 2020 Sep 25; 12(9). PMID: 32967079    Free PMC article.
Review.
The CNS and the Brain Tumor Microenvironment: Implications for Glioblastoma Immunotherapy.
Fiona A Desland, Adília Hormigo.
Int J Mol Sci, 2020 Oct 09; 21(19). PMID: 33027976    Free PMC article.
Review.
Hypoxic Melanoma Cells Deliver microRNAs to Dendritic Cells and Cytotoxic T Lymphocytes through Connexin-43 Channels.
Andrés Tittarelli, Mariela Navarrete, +2 authors, Flavio Salazar-Onfray.
Int J Mol Sci, 2020 Oct 18; 21(20). PMID: 33066331    Free PMC article.
From Conventional Therapies to Immunotherapy: Melanoma Treatment in Review.
Lukasz Kuryk, Laura Bertinato, +5 authors, Mariangela Garofalo.
Cancers (Basel), 2020 Oct 24; 12(10). PMID: 33092131    Free PMC article.
Review.
Lung Carcinoma Cells Secrete Exosomal MALAT1 to Inhibit Dendritic Cell Phagocytosis, Inflammatory Response, Costimulatory Molecule Expression and Promote Dendritic Cell Autophagy via AKT/mTOR Pathway.
Yanyan Liu, Zhucheng Yin, +6 authors, Xinjun Liang.
Onco Targets Ther, 2020 Oct 30; 13. PMID: 33116646    Free PMC article.
First-Line Immune-Checkpoint Inhibitors in Non-Small Cell Lung Cancer: Current Landscape and Future Progress.
Zhangfeng Huang, Wenhao Su, +6 authors, Wenjie Jiao.
Front Pharmacol, 2020 Oct 30; 11. PMID: 33117170    Free PMC article.
Review.
Evolving Paradigms in the Management and Outcomes of Sarcomatoid Renal Cell Carcinoma in the Era of Immune Checkpoint Inhibitors.
Ragia Aly, Amandeep S Aujla, +3 authors, Sheila Kalathil.
World J Oncol, 2020 Oct 30; 11(5). PMID: 33117461    Free PMC article.
Review.
The transcription factor C/EBPβ orchestrates dendritic cell maturation and functionality under homeostatic and malignant conditions.
Florian Scholz, Michael Grau, +7 authors, Uta E Höpken.
Proc Natl Acad Sci U S A, 2020 Oct 07; 117(42). PMID: 33020261    Free PMC article.
Helpless Priming Sends CD8+ T Cells on the Road to Exhaustion.
Julia Busselaar, Sun Tian, Hans van Eenennaam, Jannie Borst.
Front Immunol, 2020 Oct 31; 11. PMID: 33123174    Free PMC article.
Pancreatic Adenocarcinoma Invasiveness and the Tumor Microenvironment: From Biology to Clinical Trials.
Isabel Mejia, Sandhya Bodapati, Kathryn T Chen, Begoña Díaz.
Biomedicines, 2020 Oct 15; 8(10). PMID: 33050151    Free PMC article.
Review.
Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy.
Leila Motedayen Aval, James E Pease, Rohini Sharma, David J Pinato.
J Clin Med, 2020 Oct 22; 9(10). PMID: 33081170    Free PMC article.
Review.
[Checkpoint inhibitors for cancer therapy].
Hilke Zander, Susanne Müller-Egert, +3 authors, Jörg Engelbergs.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2020 Oct 02; 63(11). PMID: 33001218    Free PMC article.
Review.
Crosstalk Between Mesenchymal Stromal Cells and Tumor-Associated Macrophages in Gastric Cancer.
Ping Zheng, Wei Li.
Front Oncol, 2020 Nov 10; 10. PMID: 33163402    Free PMC article.
Review.
Metformin and cancer immunity.
Ruixia Ma, Bin Yi, Adam I Riker, Yaguang Xi.
Acta Pharmacol Sin, 2020 Sep 02; 41(11). PMID: 32868904    Free PMC article.
Review.
Emerging Blood-Based Biomarkers for Predicting Response to Checkpoint Immunotherapy in Non-Small-Cell Lung Cancer.
Shumin Li, Chengyan Zhang, Guanchao Pang, Pingli Wang.
Front Immunol, 2020 Nov 13; 11. PMID: 33178229    Free PMC article.
Systematic Review.
Immune Checkpoints and CAR-T Cells: The Pioneers in Future Cancer Therapies?
Negar Hosseinkhani, Afshin Derakhshani, +9 authors, Behzad Baradaran.
Int J Mol Sci, 2020 Nov 11; 21(21). PMID: 33167514    Free PMC article.
Review.
ERBB2-CAR-Engineered Cytokine-Induced Killer Cells Exhibit Both CAR-Mediated and Innate Immunity Against High-Risk Rhabdomyosarcoma.
Michael Merker, Juliane Wagner, +9 authors, Eva Rettinger.
Front Immunol, 2020 Nov 17; 11. PMID: 33193388    Free PMC article.
Nanoparticle cancer vaccines: Design considerations and recent advances.
Jingjing Liu, Lei Miao, +2 authors, Guihua Huang.
Asian J Pharm Sci, 2020 Nov 17; 15(5). PMID: 33193861    Free PMC article.
Review.
Long Noncoding RNAs, New Critical Regulators in Cancer Immunity.
Minjie Wu, Peifen Fu, +2 authors, Aifu Lin.
Front Oncol, 2020 Nov 17; 10. PMID: 33194608    Free PMC article.
Review.
Identification of Prognostic Model and Biomarkers for Cancer Stem Cell Characteristics in Glioblastoma by Network Analysis of Multi-Omics Data and Stemness Indices.
Jianyang Du, Xiuwei Yan, +9 authors, Shaoshan Hu.
Front Cell Dev Biol, 2020 Nov 17; 8. PMID: 33195193    Free PMC article.
The immune phenotype of tongue squamous cell carcinoma predicts early relapse and poor prognosis.
Giuseppe Troiano, Corrado Rubini, +6 authors, Marco Mascitti.
Cancer Med, 2020 Oct 14; 9(22). PMID: 33047888    Free PMC article.
PD-1 Inhibitors: Do they have a Future in the Treatment of Glioblastoma?
Mustafa Khasraw, David A Reardon, Michael Weller, John H Sampson.
Clin Cancer Res, 2020 Jun 13; 26(20). PMID: 32527943    Free PMC article.
Review.
Immunotherapeutic Targets and Therapy for Renal Cell Carcinoma.
Pierangela Sepe, Alessia Mennitto, Francesca Corti, Giuseppe Procopio.
Immunotargets Ther, 2020 Nov 24; 9. PMID: 33224904    Free PMC article.
Review.
Eftilagimod alpha, a soluble lymphocyte activation gene-3 (LAG-3) protein plus pembrolizumab in patients with metastatic melanoma.
Victoria Atkinson, Adnan Khattak, +6 authors, Frederic Triebel.
J Immunother Cancer, 2020 Nov 22; 8(2). PMID: 33219094    Free PMC article.
Clinical Pharmacokinetics and Pharmacodynamics of Immune Checkpoint Inhibitors.
Maddalena Centanni, Dirk Jan A R Moes, +2 authors, J G Coen van Hasselt.
Clin Pharmacokinet, 2019 Mar 01; 58(7). PMID: 30815848    Free PMC article.
Highly Cited. Review.
Dexosomes as a cell-free vaccine for cancer immunotherapy.
Sepideh Nikfarjam, Jafar Rezaie, Fatah Kashanchi, Reza Jafari.
J Exp Clin Cancer Res, 2020 Nov 25; 39(1). PMID: 33228747    Free PMC article.
Review.
Hyperthermia Targeting the Tumor Microenvironment Facilitates Immune Checkpoint Inhibitors.
Zihui Li, Jie Deng, Jianhai Sun, Yanling Ma.
Front Immunol, 2020 Nov 27; 11. PMID: 33240283    Free PMC article.
Review.
Development and Validation of an Individualized Immune-Related Gene Pairs Prognostic Signature in Papillary Renal Cell Carcinoma.
Xianghong Zhou, Shi Qiu, +4 authors, Qiang Wei.
Front Genet, 2020 Nov 27; 11. PMID: 33240321    Free PMC article.
Siglec-7 is a predictive biomarker for the efficacy of cancer vaccination against metastatic colorectal cancer.
Kensuke Yamada, Shoichi Hazama, +23 authors, Hiroaki Nagano.
Oncol Lett, 2020 Nov 27; 21(1). PMID: 33240416    Free PMC article.
Immunotherapies in ovarian cancer.
Elena García-Martínez, J Alejandro Pérez-Fidalgo.
EJC Suppl, 2020 Nov 27; 15. PMID: 33240447    Free PMC article.
Bilateral Posterior Uveitis and Retinal Detachment During Immunotherapy: A Case Report and Literature Review.
Ling Peng, Qi-Qi Mao, +8 authors, Hai Jiang.
Front Oncol, 2020 Nov 27; 10. PMID: 33240807    Free PMC article.
Combination of Irreversible Electroporation and STING Agonist for Effective Cancer Immunotherapy.
Eun-Jin Go, Hannah Yang, +6 authors, Wooram Park.
Cancers (Basel), 2020 Oct 30; 12(11). PMID: 33114476    Free PMC article.
Clinical Impact of Tumor-Infiltrating Lymphocytes and PD-L1-Positive Cells as Prognostic and Predictive Biomarkers in Urological Malignancies and Retroperitoneal Sarcoma.
Makito Miyake, Shunta Hori, +5 authors, Kiyohide Fujimoto.
Cancers (Basel), 2020 Oct 31; 12(11). PMID: 33121123    Free PMC article.
Review.
A Holistic Perspective: Exosomes Shuttle between Nerves and Immune Cells in the Tumor Microenvironment.
Mihnea P Dragomir, Vlad Moisoiu, +5 authors, George A Calin.
J Clin Med, 2020 Nov 05; 9(11). PMID: 33142779    Free PMC article.
Review.
Nanomaterial-Based Tumor Photothermal Immunotherapy.
Peng Xu, Feng Liang.
Int J Nanomedicine, 2020 Nov 28; 15. PMID: 33244232    Free PMC article.
Review.
Plasmacytoid Dendritic Cell (pDC) Infiltration Correlate with Tumor Infiltrating Lymphocytes, Cancer Immunity, and Better Survival in Triple Negative Breast Cancer (TNBC) More Strongly than Conventional Dendritic Cell (cDC).
Masanori Oshi, Stephanie Newman, +5 authors, Kazuaki Takabe.
Cancers (Basel), 2020 Nov 18; 12(11). PMID: 33198125    Free PMC article.
Tumor Microenvironment and Immunotherapy Response in Head and Neck Cancer.
Panagiota Economopoulou, Ioannis Kotsantis, Amanda Psyrri.
Cancers (Basel), 2020 Nov 19; 12(11). PMID: 33203092    Free PMC article.
Review.</