Microenvironmental clues for glioma immunotherapy. Michael Platten, Katharina Ochs, +2 authors, Dieter Lemke, Christiane Opitz, Wolfgang Wick. less Curr Neurol Neurosci Rep, 2014 Mar 08; 14(4). PMID: 24604058 Review.
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Radiation for Awakening the Dormant Immune System, a Promising Challenge to be Explored. Luis de la Cruz-Merino, Ana Illescas-Vacas, +3 authors, Ana Grueso-López, Antonio Barco-Sánchez, Carlos Míguez-Sánchez, Cancer Immunotherapies Spanish Group (GETICA). less Front Immunol, 2014 Mar 29; 5. PMID: 24672524 Free PMC article. Review.
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Molecular pathways and therapeutic targets in lung cancer. Emma Shtivelman, Thomas Hensing, +4 authors, George R Simon, Phillip A Dennis, Gregory A Otterson, Raphael Bueno, Ravi Salgia. less Oncotarget, 2014 Apr 12; 5(6). PMID: 24722523 Free PMC article. Highly Cited. Review.
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Regulatory T cells and myeloid-derived suppressor cells in the tumor microenvironment undergo Fas-dependent cell death during IL-2/αCD40 therapy. Jonathan M Weiss, Jeff J Subleski, +6 authors, Tim Back, Xin Chen, Stephanie K Watkins, Hideo Yagita, Thomas J Sayers, William J Murphy, Robert H Wiltrout. less J Immunol, 2014 May 09; 192(12). PMID: 24808361 Free PMC article.
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Radiation-induced autophagy potentiates immunotherapy of cancer via up-regulation of mannose 6-phosphate receptor on tumor cells in mice. Sungjune Kim, Rupal Ramakrishnan, +5 authors, Sergio Lavilla-Alonso, Prakash Chinnaiyan, Nikhil Rao, Erin Fowler, John Heine, Dmitry I Gabrilovich. less Cancer Immunol Immunother, 2014 Jun 20; 63(10). PMID: 24943275 Free PMC article.
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Radiation and anti-PD-L1 antibody combinatorial therapy induces T cell-mediated depletion of myeloid-derived suppressor cells and tumor regression. Liufu Deng, Hua Liang, +2 authors, Byron Burnette, Ralph R Weicheslbaum, Yang-Xin Fu. less Oncoimmunology, 2014 Jul 23; 3. PMID: 25050217 Free PMC article.
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Blockade of the programmed death-1 pathway restores sarcoidosis CD4(+) T-cell proliferative capacity. Nicole A Braun, Lindsay J Celada, +14 authors, Jose D Herazo-Maya, Susamma Abraham, Guzel Shaginurova, Carla M Sevin, Jan Grutters, Daniel A Culver, Ryszard Dworski, James Sheller, Pierre P Massion, Vasiliy V Polosukhin, Joyce E Johnson, Naftali Kaminski, David S Wilkes, Kyra A Oswald-Richter, Wonder P Drake. less Am J Respir Crit Care Med, 2014 Jul 30; 190(5). PMID: 25073001 Free PMC article.
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Radiation-induced survival responses promote immunogenic modulation to enhance immunotherapy in combinatorial regimens. Sofia R Gameiro, Andressa Ardiani, Anna Kwilas, James W Hodge. Oncoimmunology, 2014 Aug 07; 3. PMID: 25097803 Free PMC article.
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Reduction of myeloid-derived suppressor cells and lymphoma growth by a natural triterpenoid. Faisal F Y Radwan, Azim Hossain, +5 authors, Jason M God, Nathan Leaphart, Michelle Elvington, Mitzi Nagarkatti, Stephen Tomlinson, Azizul Haque. less J Cell Biochem, 2014 Aug 22; 116(1). PMID: 25142864 Free PMC article.
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Combining radiation and immunotherapy: a new systemic therapy for solid tumors? Chad Tang, Xiaohong Wang, +14 authors, Hendrick Soh, Steven Seyedin, Maria Angelica Cortez, Sunil Krishnan, Erminia Massarelli, David Hong, Aung Naing, Adi Diab, Daniel Gomez, Huiping Ye, John Heymach, Ristuko Komaki, James P Allison, Padmanee Sharma, James W Welsh. less Cancer Immunol Res, 2014 Sep 05; 2(9). PMID: 25187273 Free PMC article. Highly Cited. Review.
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The programmed death-1 immune-suppressive pathway: barrier to antitumor immunity. Suzanne Ostrand-Rosenberg, Lucas A Horn, Samuel T Haile. J Immunol, 2014 Oct 05; 193(8). PMID: 25281753 Free PMC article. Highly Cited. Review.
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Chemoradiotherapy-induced upregulation of PD-1 antagonizes immunity to HPV-related oropharyngeal cancer. Falguni Parikh, Dorothée Duluc, +14 authors, Naoko Imai, Amelia Clark, Krzys Misiukiewicz, Marcello Bonomi, Vishal Gupta, Alexis Patsias, Michael Parides, Elizabeth G Demicco, David Y Zhang, Seunghee Kim-Schulze, Johnny Kao, Sacha Gnjatic, Sangkon Oh, Marshall R Posner, Andrew G Sikora. less Cancer Res, 2014 Oct 17; 74(24). PMID: 25320012 Free PMC article.
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Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway. Kim C Ohaegbulam, Amer Assal, +2 authors, Eszter Lazar-Molnar, Yu Yao, Xingxing Zang. less Trends Mol Med, 2014 Dec 03; 21(1). PMID: 25440090 Free PMC article. Highly Cited. Review.
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Combination regimens of radiation therapy and therapeutic cancer vaccines: mechanisms and opportunities. Charlie Garnett-Benson, James W Hodge, Sofia R Gameiro. Semin Radiat Oncol, 2014 Dec 08; 25(1). PMID: 25481266 Free PMC article. Review.
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B7H1/CD80 interaction augments PD-1-dependent T cell apoptosis and ameliorates graft-versus-host disease. Ruishu Deng, Kaniel Cassady, +6 authors, Xiaofan Li, Sheng Yao, Mingfeng Zhang, Jeremy Racine, Jeffrey Lin, Lieping Chen, Defu Zeng. less J Immunol, 2014 Dec 10; 194(2). PMID: 25488990 Free PMC article.
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STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors. Liufu Deng, Hua Liang, +12 authors, Meng Xu, Xuanming Yang, Byron Burnette, Ainhoa Arina, Xiao-Dong Li, Helena Mauceri, Michael Beckett, Thomas Darga, Xiaona Huang, Thomas F Gajewski, Zhijian J Chen, Yang-Xin Fu, Ralph R Weichselbaum. less Immunity, 2014 Dec 18; 41(5). PMID: 25517616 Free PMC article. Highly Cited.
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Stereotactic Radiation Therapy Augments Antigen-Specific PD-1-Mediated Antitumor Immune Responses via Cross-Presentation of Tumor Antigen. Andrew B Sharabi, Christopher J Nirschl, +5 authors, Christina M Kochel, Thomas R Nirschl, Brian J Francica, Esteban Velarde, Theodore L Deweese, Charles G Drake. less Cancer Immunol Res, 2014 Dec 21; 3(4). PMID: 25527358 Free PMC article. Highly Cited.
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Immune Checkpoint Blockade in Cancer Therapy. Michael A Postow, Margaret K Callahan, Jedd D Wolchok. J Clin Oncol, 2015 Jan 22; 33(17). PMID: 25605845 Free PMC article. Highly Cited. Review.
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Radiation meets immunotherapy - a perfect match in the era of combination therapy? Klara Soukup, Xinhui Wang. Int J Radiat Biol, 2015 Jan 30; 91(4). PMID: 25630486 Free PMC article. Review.
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Blockade of PD-1/PD-L1 promotes adoptive T-cell immunotherapy in a tolerogenic environment. Stephen J P Blake, Alan L H Ching, +4 authors, Tony J Kenna, Ryan Galea, Justin Large, Hideo Yagita, Raymond J Steptoe. less PLoS One, 2015 Mar 06; 10(3). PMID: 25741704 Free PMC article.
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Novel strategies for inhibiting PD-1 pathway-mediated immune suppression while simultaneously delivering activating signals to tumor-reactive T cells. Suzanne Ostrand-Rosenberg, Lucas A Horn, Juan A Alvarez. Cancer Immunol Immunother, 2015 Mar 21; 64(10). PMID: 25792524 Free PMC article. Review.
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PD-L1 checkpoint blockade prevents immune dysfunction and leukemia development in a mouse model of chronic lymphocytic leukemia. Fabienne McClanahan, Bola Hanna, +4 authors, Shaun Miller, Andrew James Clear, Peter Lichter, John G Gribben, Martina Seiffert. less Blood, 2015 Mar 25; 126(2). PMID: 25800048 Free PMC article. Highly Cited.
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Peripheral myeloid-derived suppressor and T regulatory PD-1 positive cells predict response to neoadjuvant short-course radiotherapy in rectal cancer patients. Maria Napolitano, Crescenzo D'Alterio, +11 authors, Eleonora Cardone, Anna Maria Trotta, Biagio Pecori, Daniela Rega, Ugo Pace, Dario Scala, Giosuè Scognamiglio, Fabiana Tatangelo, Carmela Cacciapuoti, Roberto Pacelli, Paolo Delrio, Stefania Scala. less Oncotarget, 2015 Apr 01; 6(10). PMID: 25823653 Free PMC article.
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Synergy of cancer immunotherapy and radiotherapy. Aaron S Mansfield, Sean S Park, Haidong Dong. Aging (Albany NY), 2015 Apr 15; 7(3). PMID: 25868470 Free PMC article.
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Ablative Tumor Radiation Can Change the Tumor Immune Cell Microenvironment to Induce Durable Complete Remissions. Alexander Filatenkov, Jeanette Baker, +11 authors, Antonia M S Mueller, Justin Kenkel, G-One Ahn, Suparna Dutt, Nigel Zhang, Holbrook Kohrt, Kent Jensen, Sussan Dejbakhsh-Jones, Judith A Shizuru, Robert N Negrin, Edgar G Engleman, Samuel Strober. less Clin Cancer Res, 2015 Apr 15; 21(16). PMID: 25869387 Free PMC article. Highly Cited.
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Expression of programmed cell death ligand 1 (PD-L1) and prevalence of tumor-infiltrating lymphocytes (TILs) in chordoma. Yong Feng, Jacson Shen, +7 authors, Yan Gao, Yunfei Liao, Gregory Cote, Edwin Choy, Ivan Chebib, Henry Mankin, Francis Hornicek, Zhenfeng Duan. less Oncotarget, 2015 Apr 15; 6(13). PMID: 25871477 Free PMC article.
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The abscopal effect of local radiotherapy: using immunotherapy to make a rare event clinically relevant. Kobe Reynders, Tim Illidge, +2 authors, Shankar Siva, Joe Y Chang, Dirk De Ruysscher. less Cancer Treat Rev, 2015 Apr 16; 41(6). PMID: 25872878 Free PMC article. Highly Cited. Review.
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Trial Watch: Radioimmunotherapy for oncological indications. Norma Bloy, Jonathan Pol, +7 authors, Gwenola Manic, Ilio Vitale, Alexander Eggermont, Jérôme Galon, Eric Tartour, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi. less Oncoimmunology, 2015 May 06; 3(9). PMID: 25941606 Free PMC article. Review.
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Author's view: radiation and immunotherapy as systemic therapy for solid tumors. Steven N Seyedin, Chad Tang, James W Welsh. Oncoimmunology, 2015 May 08; 4(3). PMID: 25949899 Free PMC article.
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Stereotactic radiation therapy combined with immunotherapy: augmenting the role of radiation in local and systemic treatment. Andrew B Sharabi, Phuoc T Tran, +2 authors, Michael Lim, Charles G Drake, Theodore L Deweese. less Oncology (Williston Park), 2015 May 17; 29(5). PMID: 25979541 Free PMC article. Review.
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Novel immunologic approaches in lymphoma: unleashing the brakes on the immune system. Loretta J Nastoupil, Sattva S Neelapu. Curr Oncol Rep, 2015 May 20; 17(7). PMID: 25986722 Review.
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Emerging Treatment Paradigms in Radiation Oncology. Quynh-Thu Le, Hiroki Shirato, Amato J Giaccia, Albert C Koong. Clin Cancer Res, 2015 May 21; 21(15). PMID: 25991820 Free PMC article. Review.
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Resistance to Antiangiogenic Therapy Is Associated with an Immunosuppressive Tumor Microenvironment in Metastatic Renal Cell Carcinoma. Xian-De Liu, Anh Hoang, +20 authors, Lijun Zhou, Sarathi Kalra, Alper Yetil, Mianen Sun, Zhiyong Ding, Xuesong Zhang, Shanshan Bai, Peter German, Pheroze Tamboli, Priya Rao, Jose A Karam, Christopher Wood, Surena Matin, Amado Zurita, Axel Bex, Arjan W Griffioen, Jianjun Gao, Padmanee Sharma, Nizar Tannir, Kanishka Sircar, Eric Jonasch. less Cancer Immunol Res, 2015 May 28; 3(9). PMID: 26014097 Free PMC article.
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The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence. Holly E Barker, James T E Paget, Aadil A Khan, Kevin J Harrington. Nat Rev Cancer, 2015 Jun 25; 15(7). PMID: 26105538 Free PMC article. Highly Cited. Review.
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Opportunities and challenges of radiotherapy for treating cancer. Dörthe Schaue, William H McBride. Nat Rev Clin Oncol, 2015 Jul 01; 12(9). PMID: 26122185 Free PMC article. Highly Cited. Review.
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ANTI-TUMOR IMMUNE RESPONSES INDUCED BY RADIOTHERAPY: A REVIEW. Yuya Yoshimoto, Koji Kono, Yoshiyuki Suzuki. Fukushima J Med Sci, 2015 Jul 03; 61(1). PMID: 26135666 Free PMC article. Review.
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Trial Watch: Immunomodulatory monoclonal antibodies for oncological indications. Aitziber Buqué, Norma Bloy, +12 authors, Fernando Aranda, Francesca Castoldi, Alexander Eggermont, Isabelle Cremer, Wolf Hervé Fridman, Jitka Fucikova, Jérôme Galon, Aurélien Marabelle, Radek Spisek, Eric Tartour, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi. less Oncoimmunology, 2015 Jul 03; 4(4). PMID: 26137403 Free PMC article. Review.
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The antitumor immune response generated by fractionated radiation therapy may be limited by tumor cell adaptive resistance and can be circumvented by PD-L1 blockade. S J Dovedi, T M Illidge. Oncoimmunology, 2015 Jul 04; 4(7). PMID: 26140246 Free PMC article.
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Locally Advanced Non-Small Cell Lung Cancer: Optimal Chemotherapeutic Agents and Duration. Hirva Mamdani, Shadia I Jalal, Nasser Hanna. Curr Treat Options Oncol, 2015 Aug 04; 16(10). PMID: 26233240 Review.
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Development of PD-1/PD-L1 Pathway in Tumor Immune Microenvironment and Treatment for Non-Small Cell Lung Cancer. Jiabei He, Ying Hu, Mingming Hu, Baolan Li. Sci Rep, 2015 Aug 19; 5. PMID: 26279307 Free PMC article. Highly Cited. Review.
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Strategies for combining immunotherapy with radiation for anticancer therapy. Steven N Seyedin, Jonathan E Schoenhals, +14 authors, Dean A Lee, Maria A Cortez, Xiaohong Wang, Sharareh Niknam, Chad Tang, David S Hong, Aung Naing, Padmanee Sharma, James P Allison, Joe Y Chang, Daniel R Gomez, John V Heymach, Ritsuko U Komaki, Laurence J Cooper, James W Welsh. less Immunotherapy, 2015 Aug 28; 7(9). PMID: 26310908 Free PMC article. Review.
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The Next Hurdle in Cancer Immunotherapy: Overcoming the Non-T-Cell-Inflamed Tumor Microenvironment. Thomas F Gajewski. Semin Oncol, 2015 Sep 01; 42(4). PMID: 26320069 Free PMC article. Highly Cited. Review.
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Altered Biological Potential and Radioresponse of Murine Tumors in Different Microenvironments. Ik Jae Lee, Eun Jeong Lee, +4 authors, Hyojin Park, Wonwoo Kim, Sang-Jun Ha, You Keun Shin, Jinsil Seong. less Cancer Res Treat, 2015 Sep 02; 48(2). PMID: 26323643 Free PMC article.
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Subversion of anticancer immunosurveillance by radiotherapy. Laurence Zitvogel, Guido Kroemer. Nat Immunol, 2015 Sep 08; 16(10). PMID: 26343538
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Immunotherapies for bladder cancer: a new hope. Farhad Fakhrejahani, Yusuke Tomita, +3 authors, Agnes Maj-Hes, Jane B Trepel, Maria De Santis, Andrea B Apolo. less Curr Opin Urol, 2015 Sep 16; 25(6). PMID: 26372038 Free PMC article. Review.
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The potential of radiotherapy to enhance the efficacy of renal cell carcinoma therapy. Katrien De Wolf, Karim Vermaelen, +2 authors, Gert De Meerleer, Bart N Lambrecht, Piet Ost. less Oncoimmunology, 2015 Oct 16; 4(10). PMID: 26464810 Free PMC article. Review.
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Immunotherapy for advanced gastric and esophageal cancer: preclinical rationale and ongoing clinical investigations. Alexander G Raufi, Samuel J Klempner. J Gastrointest Oncol, 2015 Oct 22; 6(5). PMID: 26487950 Free PMC article. Review.
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Radio-Immunotherapy-Induced Immunogenic Cancer Cells as Basis for Induction of Systemic Anti-Tumor Immune Responses - Pre-Clinical Evidence and Ongoing Clinical Applications. Anja Derer, Lisa Deloch, +3 authors, Yvonne Rubner, Rainer Fietkau, Benjamin Frey, Udo S Gaipl. less Front Immunol, 2015 Oct 27; 6. PMID: 26500646 Free PMC article. Review.
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Immune checkpoints and immunotherapy for colorectal cancer. Preet Paul Singh, Piyush K Sharma, Gayathri Krishnan, A Craig Lockhart. Gastroenterol Rep (Oxf), 2015 Oct 30; 3(4). PMID: 26510455 Free PMC article.
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Imaging, Biodistribution, and Dosimetry of Radionuclide-Labeled PD-L1 Antibody in an Immunocompetent Mouse Model of Breast Cancer. Anders Josefsson, Jessie R Nedrow, +5 authors, Sunju Park, Sangeeta Ray Banerjee, Andrew Rittenbach, Fabien Jammes, Benjamin Tsui, George Sgouros. less Cancer Res, 2015 Nov 12; 76(2). PMID: 26554829 Free PMC article. Highly Cited.
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Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors. Jason R Baird, David Friedman, +6 authors, Benjamin Cottam, Thomas W Dubensky, David B Kanne, Shelly Bambina, Keith Bahjat, Marka R Crittenden, Michael J Gough. less Cancer Res, 2015 Nov 15; 76(1). PMID: 26567136 Free PMC article. Highly Cited.
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Interferons and the Immunogenic Effects of Cancer Therapy. Andy J Minn. Trends Immunol, 2015 Nov 26; 36(11). PMID: 26604042 Free PMC article. Review.
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Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging. Roy L Maute, Sydney R Gordon, +10 authors, Aaron T Mayer, Melissa N McCracken, Arutselvan Natarajan, Nan Guo Ring, Richard Kimura, Jonathan M Tsai, Aashish Manglik, Andrew C Kruse, Sanjiv S Gambhir, Irving L Weissman, Aaron M Ring. less Proc Natl Acad Sci U S A, 2015 Nov 26; 112(47). PMID: 26604307 Free PMC article. Highly Cited.
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Adjuvant therapy for pancreas cancer in an era of value based cancer care. Daniel H Ahn, Terence M Williams, +2 authors, Daniel A Goldstein, Bassel El-Rayes, Tanios Bekaii-Saab. less Cancer Treat Rev, 2015 Dec 02; 42. PMID: 26620819 Free PMC article. Review.
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Immunomodulatory effects of radiation: what is next for cancer therapy? Anita Kumari, Samantha S Simon, Tomika D Moody, Charlie Garnett-Benson. Future Oncol, 2015 Dec 02; 12(2). PMID: 26621553 Free PMC article. Review.
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Novel radiotherapy approaches for lung cancer: combining radiation therapy with targeted and immunotherapies. Charles B Simone, Stuart H Burri, John H Heinzerling. Transl Lung Cancer Res, 2015 Dec 03; 4(5). PMID: 26629423 Free PMC article. Review.
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Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation. Matthias Leisegang, Boris Engels, +9 authors, Karin Schreiber, Poh Yin Yew, Kazuma Kiyotani, Christian Idel, Ainhoa Arina, Jaikumar Duraiswamy, Ralph R Weichselbaum, Wolfgang Uckert, Yusuke Nakamura, Hans Schreiber. less Clin Cancer Res, 2015 Dec 17; 22(11). PMID: 26667491 Free PMC article.
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Predictors of clinical response to immunotherapy with or without radiotherapy. Susan M Hiniker, Holden T Maecker, Susan J Knox. J Radiat Oncol, 2015 Dec 29; 4. PMID: 26709361 Free PMC article. Review.
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Potential biomarker for checkpoint blockade immunotherapy and treatment strategy. Zhong-Yi Dong, Si-Pei Wu, +2 authors, Ri-Qiang Liao, Shu-Mei Huang, Yi-Long Wu. less Tumour Biol, 2016 Jan 19; 37(4). PMID: 26779629 Review.
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The role of PD-L1 in the radiation response and clinical outcome for bladder cancer. Chun-Te Wu, Wen-Cheng Chen, +2 authors, Ying-Hsu Chang, Wei-Yu Lin, Miao-Fen Chen. less Sci Rep, 2016 Jan 26; 6. PMID: 26804478 Free PMC article. Highly Cited.
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The clinical and prognostic significance of CD14(+)HLA-DR(-/low) myeloid-derived suppressor cells in hepatocellular carcinoma patients receiving radiotherapy. Dong Wang, Guangyu An, +2 authors, Shengzhi Xie, Yajuan Yao, Guosheng Feng. less Tumour Biol, 2016 Feb 06; 37(8). PMID: 26846107
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STING-cytosolic DNA sensing: the backbone for an effective tumor radiation therapy. Yong Liang, Hua Peng. Ann Transl Med, 2016 Feb 24; 4(3). PMID: 26904582 Free PMC article.
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Adapting conventional cancer treatment for immunotherapy. Jian Qiao, Zhida Liu, Yang-Xin Fu. J Mol Med (Berl), 2016 Feb 26; 94(5). PMID: 26910191 Review.
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PD-1 Blockade Boosts Radiofrequency Ablation-Elicited Adaptive Immune Responses against Tumor. Liangrong Shi, Lujun Chen, +10 authors, Changping Wu, Yibei Zhu, Bin Xu, Xiao Zheng, Mingfen Sun, Wen Wen, Xichao Dai, Min Yang, Quansheng Lv, Binfeng Lu, Jingting Jiang. less Clin Cancer Res, 2016 Mar 05; 22(5). PMID: 26933175 Free PMC article.
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PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations. Weiping Zou, Jedd D Wolchok, Lieping Chen. Sci Transl Med, 2016 Mar 05; 8(328). PMID: 26936508 Free PMC article. Highly Cited. Review.
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A randomised phase II trial of Stereotactic Ablative Fractionated radiotherapy versus Radiosurgery for Oligometastatic Neoplasia to the lung (TROG 13.01 SAFRON II). Shankar Siva, Tomas Kron, +13 authors, Mathias Bressel, Marion Haas, Tao Mai, Shalini Vinod, Giuseppe Sasso, Wenchang Wong, Hien Le, Thomas Eade, Nicholas Hardcastle, Brent Chesson, Daniel Pham, Morten Høyer, Rebecca Montgomery, David Ball. less BMC Cancer, 2016 Mar 06; 16. PMID: 26944262 Free PMC article.
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Radiation Therapy Induces Macrophages to Suppress T-Cell Responses Against Pancreatic Tumors in Mice. Lena Seifert, Gregor Werba, +16 authors, Shaun Tiwari, Nancy Ngoc Giao Ly, Susanna Nguy, Sara Alothman, Dalia Alqunaibit, Antonina Avanzi, Donnele Daley, Rocky Barilla, Daniel Tippens, Alejandro Torres-Hernandez, Mautin Hundeyin, Vishnu R Mani, Cristina Hajdu, Ilenia Pellicciotta, Philmo Oh, Kevin Du, George Miller. less Gastroenterology, 2016 Mar 08; 150(7). PMID: 26946344 Free PMC article. Highly Cited.
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NF-κB functions as a molecular link between tumor cells and Th1/Tc1 T cells in the tumor microenvironment to exert radiation-mediated tumor suppression. Priscilla S Simon, Kankana Bardhan, +9 authors, May R Chen, Amy V Paschall, Chunwan Lu, Roni J Bollag, Feng-Chong Kong, JianYue Jin, Feng-Ming Kong, Jennifer L Waller, Raphael E Pollock, Kebin Liu. less Oncotarget, 2016 Mar 26; 7(17). PMID: 27014915 Free PMC article.
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Hydrogel dual delivered celecoxib and anti-PD-1 synergistically improve antitumor immunity. Yongkui Li, Min Fang, +9 authors, Jian Zhang, Jian Wang, Yu Song, Jie Shi, Wei Li, Gang Wu, Jinghua Ren, Zheng Wang, Weiping Zou, Lin Wang. less Oncoimmunology, 2016 Apr 09; 5(2). PMID: 27057439 Free PMC article.
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Immunotherapy for cancer in the central nervous system: Current and future directions. David C Binder, Andrew A Davis, Derek A Wainwright. Oncoimmunology, 2016 Apr 09; 5(2). PMID: 27057463 Free PMC article. Highly Cited. Review.
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Feasibility study of DCs/CIKs combined with thoracic radiotherapy for patients with locally advanced or metastatic non-small-cell lung cancer. Luping Zhang, Yanmei Xu, +5 authors, Jie Shen, Feng He, Dan Zhang, Zhengtang Chen, Yuzhong Duan, Jianguo Sun. less Radiat Oncol, 2016 Apr 22; 11. PMID: 27097970 Free PMC article.
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Emerging therapeutic targets in esophageal adenocarcinoma. Puja Gaur, Clayton R Hunt, Tej K Pandita. Oncotarget, 2016 Apr 23; 7(30). PMID: 27102294 Free PMC article. Review.
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Radiation therapy and the abscopal effect: a concept comes of age. John Ng, Tong Dai. Ann Transl Med, 2016 Apr 30; 4(6). PMID: 27127771 Free PMC article.
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Tumor-intrinsic oncogene pathways mediating immune avoidance. Stefani Spranger, Thomas F Gajewski. Oncoimmunology, 2016 May 04; 5(3). PMID: 27141343 Free PMC article. Highly Cited. Review.
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miR-424(322) reverses chemoresistance via T-cell immune response activation by blocking the PD-L1 immune checkpoint. Shaohua Xu, Zhen Tao, +18 authors, Bo Hai, Huagen Liang, Ying Shi, Tao Wang, Wen Song, Yong Chen, Jun OuYang, Jinhong Chen, Fanfei Kong, Yishan Dong, Shi-Wen Jiang, Weiyong Li, Ping Wang, Zhiyong Yuan, Xiaoping Wan, Chenguang Wang, Wencheng Li, Xiaoping Zhang, Ke Chen. less Nat Commun, 2016 May 06; 7. PMID: 27147225 Free PMC article. Highly Cited.
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Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma. Paula Kroon, Jules Gadiot, +7 authors, Marlies Peeters, Alessia Gasparini, Marcel A Deken, Hideo Yagita, Marcel Verheij, Jannie Borst, Christian U Blank, Inge Verbrugge. less Cancer Immunol Immunother, 2016 May 11; 65(6). PMID: 27160390 Free PMC article.
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Programmed cell death-1 blockade in recurrent disseminated Ewing sarcoma. Georgia J B McCaughan, Michael J Fulham, +5 authors, Annabelle Mahar, Judy Soper, Angela M Hong, Paul D Stalley, Martin H N Tattersall, Vivek A Bhadri. less J Hematol Oncol, 2016 Jun 05; 9(1). PMID: 27259563 Free PMC article.
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Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy. Kristina H Young, Jason R Baird, +9 authors, Talicia Savage, Benjamin Cottam, David Friedman, Shelly Bambina, David J Messenheimer, Bernard Fox, Pippa Newell, Keith S Bahjat, Michael J Gough, Marka R Crittenden. less PLoS One, 2016 Jun 10; 11(6). PMID: 27281029 Free PMC article. Highly Cited.
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Neutrophils in cancer: neutral no more. Seth B Coffelt, Max D Wellenstein, Karin E de Visser. Nat Rev Cancer, 2016 Jun 11; 16(7). PMID: 27282249 Highly Cited. Review.
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Checkpoint Inhibitors in Head and Neck Cancer: Rationale, Clinical Activity, and Potential Biomarkers. Panagiota Economopoulou, Ioannis Kotsantis, Amanda Psyrri. Curr Treat Options Oncol, 2016 Jun 18; 17(8). PMID: 27315066 Review.
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Emerging targets for radioprotection and radiosensitization in radiotherapy. Sumit Kumar, Rajnish Kumar Singh, Ramovatar Meena. Tumour Biol, 2016 Oct 27; 37(9). PMID: 27318945 Review.
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The role of myeloid cells in cancer therapies. Camilla Engblom, Christina Pfirschke, Mikael J Pittet. Nat Rev Cancer, 2016 Jun 25; 16(7). PMID: 27339708 Highly Cited. Review.
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Modern Radiotherapy Concepts and the Impact of Radiation on Immune Activation. Lisa Deloch, Anja Derer, +3 authors, Josefin Hartmann, Benjamin Frey, Rainer Fietkau, Udo S Gaipl. less Front Oncol, 2016 Jul 06; 6. PMID: 27379203 Free PMC article. Highly Cited. Review.
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Definitive chemoradiation alters the immunologic landscape and immune checkpoints in head and neck cancer. Vishwajith Sridharan, Danielle N Margalit, +10 authors, Stephanie A Lynch, Mariano Severgnini, Jun Zhou, Nicole G Chau, Guilherme Rabinowits, Jochen H Lorch, Peter S Hammerman, F Stephen Hodi, Robert I Haddad, Roy B Tishler, Jonathan D Schoenfeld. less Br J Cancer, 2016 Jul 06; 115(2). PMID: 27380136 Free PMC article.
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Mechanisms of immune evasion and current status of checkpoint inhibitors in non-small cell lung cancer. Angel Qin, David G Coffey, Edus H Warren, Nithya Ramnath. Cancer Med, 2016 Jul 16; 5(9). PMID: 27416962 Free PMC article. Review.
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Stereotactic Ablative Radiation Therapy Combined With Immunotherapy for Solid Tumors. Eric D Brooks, Jonathan E Schoenhals, +4 authors, Chad Tang, Goran Micevic, Daniel R Gomez, Joe Y Chang, James W Welsh. less Cancer J, 2016 Jul 22; 22(4). PMID: 27441745 Free PMC article. Review.
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Opportunities for Radiosensitization in the Stereotactic Body Radiation Therapy (SBRT) Era. Everett J Moding, Yvonne M Mowery, David G Kirsch. Cancer J, 2016 Jul 22; 22(4). PMID: 27441746 Free PMC article. Review.
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Challenges of Using High-Dose Fractionation Radiotherapy in Combination Therapy. Ying-Chieh Yang, Chi-Shiun Chiang. Front Oncol, 2016 Jul 23; 6. PMID: 27446811 Free PMC article. Review.
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Immuno-oncology combinations: raising the tail of the survival curve. Samuel J Harris, Jessica Brown, Juanita Lopez, Timothy A Yap. Cancer Biol Med, 2016 Jul 28; 13(2). PMID: 27458526 Free PMC article.
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Tasquinimod modulates tumor-infiltrating myeloid cells and improves the antitumor immune response to PD-L1 blockade in bladder cancer. Jessica Nakhlé, Valérie Pierron, +4 authors, Anne-Laure Bauchet, Pascale Plas, Amath Thiongane, Florence Meyer-Losic, Fabien Schmidlin. less Oncoimmunology, 2016 Jul 30; 5(6). PMID: 27471612 Free PMC article.
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The role of antagonists of the PD-1:PD-L1/PD-L2 axis in head and neck cancer treatment. Sara I Pai, Dan P Zandberg, Scott E Strome. Oral Oncol, 2016 Aug 10; 61. PMID: 27503244 Free PMC article. Review.
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PD-L1 biomarker testing for non-small cell lung cancer: truth or fiction? Claud Grigg, Naiyer A Rizvi. J Immunother Cancer, 2016 Aug 18; 4. PMID: 27532023 Free PMC article. Highly Cited. Review.
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Telltale tumor infiltrating lymphocytes (TIL) in oral, head & neck cancer. Yu Lei, Yuying Xie, +4 authors, Yee Sun Tan, Mark E Prince, Jeffrey S Moyer, Jacques Nör, Gregory T Wolf. less Oral Oncol, 2016 Aug 25; 61. PMID: 27553942 Free PMC article. Review.
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Stereotactic ablative radiotherapy and immunotherapy combinations: turning the future into systemic therapy? Richard C Walshaw, Jamie Honeychurch, Tim M Illidge. Br J Radiol, 2016 Aug 25; 89(1066). PMID: 27556933 Free PMC article. Review.
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PD-L1 expression in human cancers and its association with clinical outcomes. Xin Wang, Feifei Teng, Li Kong, Jinming Yu. Onco Targets Ther, 2016 Aug 31; 9. PMID: 27574444 Free PMC article. Highly Cited. Review.
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Immune checkpoint inhibitors: the new frontier in non-small-cell lung cancer treatment. Hazem El-Osta, Kamran Shahid, Glenn M Mills, Prakash Peddi. Onco Targets Ther, 2016 Aug 31; 9. PMID: 27574451 Free PMC article. Review.
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The influence of postoperative lymph node radiation therapy on overall survival of patients with stage III melanoma, a National Cancer Database analysis. Hasan H Danish, Kirtesh R Patel, +7 authors, Jeffrey M Switchenko, Theresa W Gillespie, Jaymin Jhaveri, Mudit Chowdhary, Mustafa Abugideiri, Keith A Delman, David H Lawson, Mohammad K Khan. less Melanoma Res, 2016 Oct 26; 26(6). PMID: 27575390 Free PMC article.
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Effects of combined sunitinib and extracranial stereotactic radiotherapy on bone marrow hematopoiesis. Johnny Kao, Jonathan Timmins, Junko Ozao-Choy, Stuart Packer. Oncol Lett, 2016 Sep 08; 12(3). PMID: 27602153 Free PMC article.
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Current clinical trials testing the combination of immunotherapy with radiotherapy. Josephine Kang, Sandra Demaria, Silvia Formenti. J Immunother Cancer, 2016 Sep 24; 4. PMID: 27660705 Free PMC article. Highly Cited.
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Radiotherapy to Control Limited Melanoma Progression Following Ipilimumab. Lauren M Kropp, Jennifer F De Los Santos, Svetlana B McKee, Robert M Conry. J Immunother, 2016 Sep 24; 39(9). PMID: 27662339 Free PMC article.
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Emerging roles of p53 and other tumour-suppressor genes in immune regulation. César Muñoz-Fontela, Anna Mandinova, Stuart A Aaronson, Sam W Lee. Nat Rev Immunol, 2016 Nov 01; 16(12). PMID: 27667712 Free PMC article. Highly Cited. Review.
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Synergy of radiotherapy and PD-1 blockade in Kras-mutant lung cancer. Grit S Herter-Sprie, Shohei Koyama, +18 authors, Houari Korideck, Josephine Hai, Jiehui Deng, Yvonne Y Li, Kevin A Buczkowski, Aaron K Grant, Soumya Ullas, Kevin Rhee, Jillian D Cavanaugh, Neermala Poudel Neupane, Camilla L Christensen, Jan M Herter, G Mike Makrigiorgos, F Stephen Hodi, Gordon J Freeman, Glenn Dranoff, Peter S Hammerman, Alec C Kimmelman, Kwok-Kin Wong. less JCI Insight, 2016 Oct 05; 1(9). PMID: 27699275 Free PMC article.
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Role of multimodality therapy in cIIIA-N2 non-small cell lung cancer: perspective. Hidehito Horinouchi. Jpn J Clin Oncol, 2016 Oct 06; 46(12). PMID: 27702837 Free PMC article.
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Current Immunotherapies for Sarcoma: Clinical Trials and Rationale. Demytra Mitsis, Valerie Francescutti, Joseph Skitzki. Sarcoma, 2016 Oct 06; 2016. PMID: 27703409 Free PMC article. Review.
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Checkpoint inhibitors and radiation treatment in Hodgkin's lymphoma : New study concepts of the German Hodgkin Study Group. C Baues, R Semrau, +4 authors, U S Gaipl, P J Bröckelmann, J Rosenbrock, A Engert, S Marnitz. less Strahlenther Onkol, 2016 Oct 06; 193(2). PMID: 27704149
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The promise of PD-1 inhibitors in gastro-esophageal cancers: microsatellite instability vs. PD-L1. Zhaohui Jin, Harry H Yoon. J Gastrointest Oncol, 2016 Oct 18; 7(5). PMID: 27747091 Free PMC article. Review.
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Trial Watch: Immunotherapy plus radiation therapy for oncological indications. Erika Vacchelli, Norma Bloy, +13 authors, Fernando Aranda, Aitziber Buqué, Isabelle Cremer, Sandra Demaria, Alexander Eggermont, Silvia Chiara Formenti, Wolf Hervé Fridman, Jitka Fucikova, Jérôme Galon, Radek Spisek, Eric Tartour, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi. less Oncoimmunology, 2016 Oct 21; 5(9). PMID: 27757313 Free PMC article. Review.
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Correlation between anti-PD-L1 tumor concentrations and tumor-specific and nonspecific biomarkers in a melanoma mouse model. Ana M Contreras-Sandoval, María Merino, +3 authors, Marcos Vasquez, Iñaki F Trocóniz, Pedro Berraondo, María J Garrido. less Oncotarget, 2016 Oct 21; 7(47). PMID: 27764774 Free PMC article.
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Radiotherapy: Changing the Game in Immunotherapy. Sandra Demaria, C Norman Coleman, Silvia C Formenti. Trends Cancer, 2016 Oct 25; 2(6). PMID: 27774519 Free PMC article. Highly Cited. Review.
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High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells. Xue Chen, Qi Zhang, +4 authors, Youjun Luo, Caixia Gao, Xibing Zhuang, Guoxiong Xu, Tiankui Qiao. less Onco Targets Ther, 2016 Nov 02; 9. PMID: 27799798 Free PMC article.
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Suppression of Type I IFN Signaling in Tumors Mediates Resistance to Anti-PD-1 Treatment That Can Be Overcome by Radiotherapy. Xiaohong Wang, Jonathan E Schoenhals, +18 authors, Ailin Li, David R Valdecanas, Huiping Ye, Fenglin Zang, Chad Tang, Ming Tang, Chang-Gong Liu, Xiuping Liu, Sunil Krishnan, James P Allison, Padmanee Sharma, Patrick Hwu, Ritsuko Komaki, Willem W Overwijk, Daniel R Gomez, Joe Y Chang, Stephen M Hahn, Maria Angelica Cortez, James W Welsh. less Cancer Res, 2016 Nov 09; 77(4). PMID: 27821490 Free PMC article. Highly Cited.
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Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model. Gwendolyn J McGinnis, David Friedman, +4 authors, Kristina H Young, Eileen Ruth S Torres, Charles R Thomas, Michael J Gough, Jacob Raber. less Oncotarget, 2016 Nov 29; 8(6). PMID: 27893434 Free PMC article.
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PD1/PD-L1 inhibition as a potential radiosensitizer in head and neck squamous cell carcinoma: a case report. Misako Nagasaka, Mark Zaki, +4 authors, Harold Kim, S Naweed Raza, George Yoo, Ho-Sheng Lin, Ammar Sukari. less J Immunother Cancer, 2016 Nov 30; 4. PMID: 27895920 Free PMC article.
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Immunotherapy of head and neck cancer: Emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting. Julie E Bauman, Ezra Cohen, +17 authors, Robert L Ferris, David J Adelstein, David M Brizel, John A Ridge, Brian O'Sullivan, Barbara A Burtness, Lisa H Butterfield, William E Carson, Mary L Disis, Bernard A Fox, Thomas F Gajewski, Maura L Gillison, James W Hodge, Quynh-Thu Le, David Raben, Scott E Strome, Jean Lynn, Shakun Malik. less Cancer, 2016 Dec 03; 123(7). PMID: 27906454 Free PMC article.
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TLR3-Induced Maturation of Murine Dendritic Cells Regulates CTL Responses by Modulating PD-L1 Trafficking. Aditi Varthaman, Hélène D Moreau, Mathieu Maurin, Philippe Benaroch. PLoS One, 2016 Dec 03; 11(12). PMID: 27911948 Free PMC article.
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Treatment Design and Rationale for a Randomized Trial of Cisplatin and Etoposide Plus Thoracic Radiotherapy Followed by Nivolumab or Placebo for Locally Advanced Non-Small-Cell Lung Cancer (RTOG 3505). David E Gerber, James J Urbanic, +7 authors, Corey Langer, Chen Hu, I-Fen Chang, Bo Lu, Benjamin Movsas, Robert Jeraj, Walter J Curran, Jeffrey D Bradley. less Clin Lung Cancer, 2016 Dec 08; 18(3). PMID: 27923550 Free PMC article.
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PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy. Abul Azad, Su Yin Lim, +9 authors, Zenobia D'Costa, Keaton Jones, Angela Diana, Owen J Sansom, Philipp Kruger, Stanley Liu, W Gillies McKenna, Omer Dushek, Ruth J Muschel, Emmanouil Fokas. less EMBO Mol Med, 2016 Dec 10; 9(2). PMID: 27932443 Free PMC article. Highly Cited.
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Immuno-Oncology: The Third Paradigm in Early Drug Development. Juan Martin-Liberal, Cinta Hierro, Maria Ochoa de Olza, Jordi Rodon. Target Oncol, 2016 Dec 21; 12(2). PMID: 27995439
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MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype. Niamh Lynam-Lennon, Susan Heavey, +8 authors, Gary Sommerville, Becky A S Bibby, Brendan Ffrench, Jennifer Quinn, Claudia Gasch, John J O'Leary, Michael F Gallagher, John V Reynolds, Stephen G Maher. less Oncotarget, 2016 Dec 22; 8(7). PMID: 28002789 Free PMC article.
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Reprogramming the immunological microenvironment through radiation and targeting Axl. Todd A Aguilera, Marjan Rafat, +12 authors, Laura Castellini, Hussein Shehade, Mihalis S Kariolis, Angela Bik-Yu Hui, Henning Stehr, Rie von Eyben, Dadi Jiang, Lesley G Ellies, Albert C Koong, Maximilian Diehn, Erinn B Rankin, Edward E Graves, Amato J Giaccia. less Nat Commun, 2016 Dec 23; 7. PMID: 28008921 Free PMC article. Highly Cited.
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The intersection of radiotherapy and immunotherapy: mechanisms and clinical implications. Michael Spiotto, Yang-Xin Fu, Ralph R Weichselbaum. Sci Immunol, 2016 Dec 27; 1(3). PMID: 28018989 Free PMC article.
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Update on immune checkpoint inhibitors in gynecological cancers. Valerie Heong, Natalie Ngoi, David Shao Peng Tan. J Gynecol Oncol, 2016 Dec 29; 28(2). PMID: 28028993 Free PMC article. Review.
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Radiotherapy and immune checkpoint blockades: a snapshot in 2016. Taeryool Koo, In Ah Kim. Radiat Oncol J, 2016 Dec 30; 34(4). PMID: 28030901 Free PMC article. Review.
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Pneumonitis in cancer patients receiving anti-PD-1 and radiotherapies: Three case reports. Chieh-Sheng Lu, Jin-Hwang Liu. Medicine (Baltimore), 2017 Jan 11; 96(1). PMID: 28072716 Free PMC article.
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Radiotherapy and immunotherapy: a beneficial liaison? Ralph R Weichselbaum, Hua Liang, Liufu Deng, Yang-Xin Fu. Nat Rev Clin Oncol, 2017 Jan 18; 14(6). PMID: 28094262 Highly Cited. Review.
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New Combination Strategies Using Programmed Cell Death 1/Programmed Cell Death Ligand 1 Checkpoint Inhibitors as a Backbone. Siwen Hu-Lieskovan, Antoni Ribas. Cancer J, 2017 Jan 24; 23(1). PMID: 28114250 Free PMC article. Review.
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Radiotherapy and MVA-MUC1-IL-2 vaccine act synergistically for inducing specific immunity to MUC-1 tumor antigen. Gilda G Hillman, Lyndsey A Reich, +7 authors, Shoshana E Rothstein, Lisa M Abernathy, Matthew D Fountain, Kali Hankerd, Christopher K Yunker, Joseph T Rakowski, Eric Quemeneur, Philippe Slos. less J Immunother Cancer, 2017 Jan 25; 5. PMID: 28116088 Free PMC article.
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A phase II trial of stereotactic body radiotherapy with concurrent anti-PD1 treatment in metastatic melanoma: evaluation of clinical and immunologic response. Katrien De Wolf, Vibeke Kruse, +5 authors, Nora Sundahl, Mireille van Gele, Ines Chevolet, Reinhart Speeckaert, Lieve Brochez, Piet Ost. less J Transl Med, 2017 Feb 01; 15(1). PMID: 28137295 Free PMC article.
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Myeloid-derived suppressor cells mediate tolerance induction in autoimmune disease. Anja Wegner, Johan Verhagen, David C Wraith. Immunology, 2017 Feb 01; 151(1). PMID: 28140447 Free PMC article.
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Metastatic small cell neuroendocrine carcinoma of the cervix treated with the PD-1 inhibitor, nivolumab: a case report. Sarah E Paraghamian, Teresa C Longoria, Ramez N Eskander. Gynecol Oncol Res Pract, 2017 Feb 09; 4. PMID: 28174665 Free PMC article.
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Irradiation enhances dendritic cell potential antitumor activity by inducing tumor cell expressing TNF-α. Lijia Chang, Zhengzheng Zhang, +3 authors, Fang Chen, Wen Zhang, Shuang Song, Shuxia Song. less Med Oncol, 2017 Feb 15; 34(3). PMID: 28194716
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Plasma levels of soluble programmed death ligand-1 may be associated with overall survival in nonsmall cell lung cancer patients receiving thoracic radiotherapy. Jing Zhao, Peng Zhang, +4 authors, Jianhua Wang, Qingsong Xi, Xueqi Zhao, Minghua Ji, Guangyuan Hu. less Medicine (Baltimore), 2017 Feb 17; 96(7). PMID: 28207525 Free PMC article.
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A meta-analysis of the abscopal effect in preclinical models: Is the biologically effective dose a relevant physical trigger? Raffaella Marconi, Silvia Strolin, Gianluca Bossi, Lidia Strigari. PLoS One, 2017 Feb 22; 12(2). PMID: 28222111 Free PMC article.
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Structure-guided development of a high-affinity human Programmed Cell Death-1: Implications for tumor immunotherapy. Eszter Lázár-Molnár, Lisa Scandiuzzi, +7 authors, Indranil Basu, Thomas Quinn, Eliezer Sylvestre, Edith Palmieri, Udupi A Ramagopal, Stanley G Nathenson, Chandan Guha, Steven C Almo. less EBioMedicine, 2017 Feb 25; 17. PMID: 28233730 Free PMC article.
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The Role of Immune Checkpoint Inhibition in the Treatment of Brain Tumors. Andrew S Luksik, Russell Maxwell, Tomas Garzon-Muvdi, Michael Lim. Neurotherapeutics, 2017 Mar 05; 14(4). PMID: 28258545 Free PMC article. Review.
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Molecular Pathways: Oncologic Pathways and Their Role in T-cell Exclusion and Immune Evasion-A New Role for the AXL Receptor Tyrosine Kinase. Todd A Aguilera, Amato J Giaccia. Clin Cancer Res, 2017 Mar 16; 23(12). PMID: 28289089 Free PMC article. Review.
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Immunotherapy for Esophageal Squamous Cell Carcinoma. Takashi Kojima, Toshihiko Doi. Curr Oncol Rep, 2017 Apr 01; 19(5). PMID: 28361224 Free PMC article. Review.
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The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1. Michele Cioffi, Sara M Trabulo, +15 authors, Mireia Vallespinos, Deepak Raj, Tony Bou Kheir, Meng-Lay Lin, Julfa Begum, Ann-Marie Baker, Ala Amgheib, Jaimy Saif, Manuel Perez, Joaquim Soriano, Manuel Desco, Maria Victoria Gomez-Gaviro, Lorena Cusso, Diego Megias, Alexandra Aicher, Christopher Heeschen. less Oncotarget, 2017 Apr 21; 8(13). PMID: 28423491 Free PMC article.
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Following the Preclinical Data: Leveraging the Abscopal Effect More Efficaciously. Wilfred Ngwa, Zi Ouyang. Front Oncol, 2017 Apr 28; 7. PMID: 28447024 Free PMC article.
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Radiation improves antitumor effect of immune checkpoint inhibitor in murine hepatocellular carcinoma model. Kyoung-Jin Kim, Ji-Hye Kim, +3 authors, Seo Jin Lee, Eun-Jung Lee, Eui-Cheol Shin, Jinsil Seong. less Oncotarget, 2017 May 04; 8(25). PMID: 28465485 Free PMC article.
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Integrative Analysis Identifies a Novel AXL-PI3 Kinase-PD-L1 Signaling Axis Associated with Radiation Resistance in Head and Neck Cancer. Heath D Skinner, Uma Giri, +15 authors, Liang P Yang, Manish Kumar, Ying Liu, Michael D Story, Curtis R Pickering, Lauren A Byers, Michelle D Williams, Jing Wang, Li Shen, Suk Y Yoo, You Hong Fan, David P Molkentine, Beth M Beadle, Raymond E Meyn, Jeffrey N Myers, John V Heymach. less Clin Cancer Res, 2017 May 10; 23(11). PMID: 28476872 Free PMC article.
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Immunotherapy for Head and Neck Squamous Cell Carcinoma: A Review of Current and Emerging Therapeutic Options. Jessica M Moskovitz, Jennifer Moy, Tanguy Y Seiwert, Robert L Ferris. Oncologist, 2017 May 17; 22(6). PMID: 28507203 Free PMC article. Review.
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Harnessing the potential synergy of combining radiation therapy and immunotherapy for thoracic malignancies. Charles B Simone, Abigail T Berman, Salma K Jabbour. Transl Lung Cancer Res, 2017 May 23; 6(2). PMID: 28529893 Free PMC article.
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Integrating immunotherapy into chemoradiation regimens for medically inoperable locally advanced non-small cell lung cancer. Salma K Jabbour, Abigail T Berman, Charles B Simone. Transl Lung Cancer Res, 2017 May 23; 6(2). PMID: 28529894 Free PMC article. Review.
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Clinical experiences of combining immunotherapy and radiation therapy in non-small cell lung cancer: lessons from melanoma. Anusha Kalbasi, Ramesh Rengan. Transl Lung Cancer Res, 2017 May 23; 6(2). PMID: 28529899 Free PMC article. Review.
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Immunotherapy and radiation therapy for operable early stage and locally advanced non-small cell lung cancer. Neil K Taunk, Andreas Rimner, +3 authors, Melissa Culligan, Joseph S Friedberg, Julie Brahmer, Jamie Chaft. less Transl Lung Cancer Res, 2017 May 23; 6(2). PMID: 28529900 Free PMC article. Review.
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Immunotherapy and radiation therapy for malignant pleural mesothelioma. Evan W Alley, Sharyn I Katz, Keith A Cengel, Charles B Simone. Transl Lung Cancer Res, 2017 May 23; 6(2). PMID: 28529903 Free PMC article. Review.
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Combining radiotherapy with immunotherapy: the past, the present and the future. Evert J Van Limbergen, Dirk K De Ruysscher, +8 authors, Veronica Olivo Pimentel, Damiënne Marcus, Maaike Berbee, Ann Hoeben, Nicolle Rekers, Jan Theys, Ala Yaromina, Ludwig J Dubois, Philippe Lambin. less Br J Radiol, 2017 May 26; 90(1076). PMID: 28541096 Free PMC article. Review.
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Immunotherapy and radiation in glioblastoma. Solmaz Sahebjam, Andrew Sharabi, +2 authors, Michael Lim, Pravin Kesarwani, Prakash Chinnaiyan. less J Neurooncol, 2017 Jun 02; 134(3). PMID: 28567588 Review.
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Immunotherapy in head and neck cancer: aiming at EXTREME precision. Petr Szturz, Jan B Vermorken. BMC Med, 2017 Jun 03; 15(1). PMID: 28571578 Free PMC article.
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Modulating Both Tumor Cell Death and Innate Immunity Is Essential for Improving Radiation Therapy Effectiveness. Qiuji Wu, Awatef Allouch, +4 authors, Isabelle Martins, Catherine Brenner, Nazanine Modjtahedi, Eric Deutsch, Jean-Luc Perfettini. less Front Immunol, 2017 Jun 13; 8. PMID: 28603525 Free PMC article. Review.
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Intratumoral infection by CMV may change the tumor environment by directly interacting with tumor-associated macrophages to promote cancer immunity. Dan A Erkes, Nicole A Wilski, Christopher M Snyder. Hum Vaccin Immunother, 2017 Jun 13; 13(8). PMID: 28604162 Free PMC article. Review.
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Limitations and opportunities for immune checkpoint inhibitors in pediatric malignancies. Jeong A Park, Nai-Kong V Cheung. Cancer Treat Rev, 2017 Jun 18; 58. PMID: 28622628 Free PMC article. Review.
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DNA Damage and Repair Biomarkers of Immunotherapy Response. Kent W Mouw, Michael S Goldberg, Panagiotis A Konstantinopoulos, Alan D D'Andrea. Cancer Discov, 2017 Jun 21; 7(7). PMID: 28630051 Free PMC article. Highly Cited. Review.
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Programmed death-1 pathway blockade produces a synergistic antitumor effect: combined application in ovarian cancer. Xinxin Zhu, Jinghe Lang. J Gynecol Oncol, 2017 Jun 29; 28(5). PMID: 28657225 Free PMC article. Review.
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A phase I/II trial of fixed-dose stereotactic body radiotherapy with sequential or concurrent pembrolizumab in metastatic urothelial carcinoma: evaluation of safety and clinical and immunologic response. Nora Sundahl, Katrien De Wolf, +11 authors, Sylvie Rottey, Karel Decaestecker, Daan De Maeseneer, Annabel Meireson, Els Goetghebeur, Valérie Fonteyne, Sofie Verbeke, Pieter De Visschere, Dries Reynders, Mireille Van Gele, Lieve Brochez, Piet Ost. less J Transl Med, 2017 Jul 01; 15(1). PMID: 28662677 Free PMC article.
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Dose-dependent enhancement of T-lymphocyte priming and CTL lysis following ionizing radiation in an engineered model of oral cancer. Megan Morisada, Ellen C Moore, +5 authors, Rachel Hodge, Jay Friedman, Harrison A Cash, James W Hodge, James B Mitchell, Clint T Allen. less Oral Oncol, 2017 Jul 10; 71. PMID: 28688697 Free PMC article.
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Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment. Qianghu Wang, Baoli Hu, +31 authors, Xin Hu, Hoon Kim, Massimo Squatrito, Lisa Scarpace, Ana C deCarvalho, Sali Lyu, Pengping Li, Yan Li, Floris Barthel, Hee Jin Cho, Yu-Hsi Lin, Nikunj Satani, Emmanuel Martinez-Ledesma, Siyuan Zheng, Edward Chang, Charles-Etienne Gabriel Sauvé, Adriana Olar, Zheng D Lan, Gaetano Finocchiaro, Joanna J Phillips, Mitchel S Berger, Konrad R Gabrusiewicz, Guocan Wang, Eskil Eskilsson, Jian Hu, Tom Mikkelsen, Ronald A DePinho, Florian Muller, Amy B Heimberger, Erik P Sulman, Do-Hyun Nam, Roel G W Verhaak. less Cancer Cell, 2017 Jul 12; 32(1). PMID: 28697342 Free PMC article. Highly Cited.
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A perspective on the impact of radiation therapy on the immune rheostat. William H McBride, Ekambaram Ganapathy, +3 authors, Mi-Heon Lee, Jean P Nesseler, Christine Nguyen, Dörthe Schaue. less Br J Radiol, 2017 Jul 15; 90(1078). PMID: 28707537 Free PMC article. Review.
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Inhibitors of the PD-1/PD-L1 axis for the treatment of head and neck cancer: current status and future perspectives. Xiongwen Ran, Kai Yang. Drug Des Devel Ther, 2017 Jul 20; 11. PMID: 28721019 Free PMC article. Review.
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Tumor cell PD-L1 predicts poor local control for rectal cancer patients following neoadjuvant radiotherapy. Lingdong Shao, Qingqin Peng, +5 authors, Kaixin Du, Junyan He, Yaping Dong, Xiaoyi Lin, Jinluan Li, Junxin Wu. less Cancer Manag Res, 2017 Jul 20; 9. PMID: 28721097 Free PMC article.
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PD-1/PD-L blockade in gastrointestinal cancers: lessons learned and the road toward precision immunotherapy. Junyu Long, Jianzhen Lin, +7 authors, Anqiang Wang, Liangcai Wu, Yongchang Zheng, Xiaobo Yang, Xueshuai Wan, Haifeng Xu, Shuguang Chen, Haitao Zhao. less J Hematol Oncol, 2017 Aug 05; 10(1). PMID: 28774337 Free PMC article. Review.
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Clinical Trials Investigating Immune Checkpoint Blockade in Glioblastoma. Russell Maxwell, Christopher M Jackson, Michael Lim. Curr Treat Options Oncol, 2017 Aug 09; 18(8). PMID: 28785997 Review.
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Immunotherapy Combined with Large Fractions of Radiotherapy: Stereotactic Radiosurgery for Brain Metastases-Implications for Intraoperative Radiotherapy after Resection. Carsten Herskind, Frederik Wenz, Frank A Giordano. Front Oncol, 2017 Aug 10; 7. PMID: 28791250 Free PMC article. Review.
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Preclinical immunoPET/CT imaging using Zr-89-labeled anti-PD-L1 monoclonal antibody for assessing radiation-induced PD-L1 upregulation in head and neck cancer and melanoma. Masahiro Kikuchi, David A Clump, +6 authors, Raghvendra M Srivastava, Lingyi Sun, Dexing Zeng, Julio A Diaz-Perez, Carolyn J Anderson, W Barry Edwards, Robert L Ferris. less Oncoimmunology, 2017 Aug 16; 6(7). PMID: 28811971 Free PMC article.
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Use of programmed cell death protein ligand 1 assay to predict the outcomes of non-small cell lung cancer patients treated with immune checkpoint inhibitors. Carmelo Tibaldi, Alice Lunghi, Editta Baldini. World J Clin Oncol, 2017 Aug 30; 8(4). PMID: 28848698 Free PMC article. Review.
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Stimulating Innate Immunity to Enhance Radiation Therapy-Induced Tumor Control. Jason R Baird, Arta M Monjazeb, +4 authors, Omid Shah, Heather McGee, William J Murphy, Marka R Crittenden, Michael J Gough. less Int J Radiat Oncol Biol Phys, 2017 Sep 06; 99(2). PMID: 28871985 Free PMC article. Review.
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PD-1 mRNA expression in peripheral blood cells and its modulation characteristics in cancer patients. Wei Wang, Ge Shen, +12 authors, Shikai Wu, Shiping Song, Yanli Ni, Zhuoyao Suo, Xiangying Meng, Dan Li, Lin Zhou, Rimin Hao, Yaowei Zhao, Li Bai, Lili Hou, Bing Liu, Guangxian Liu. less Oncotarget, 2017 Sep 09; 8(31). PMID: 28881603 Free PMC article.
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PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer. Benjamin A Kansy, Fernando Concha-Benavente, +13 authors, Raghvendra M Srivastava, Hyun-Bae Jie, Gulidanna Shayan, Yu Lei, Jessica Moskovitz, Jennifer Moy, Jing Li, Sven Brandau, Stephan Lang, Nicole C Schmitt, Gordon J Freeman, William E Gooding, David A Clump, Robert L Ferris. less Cancer Res, 2017 Sep 15; 77(22). PMID: 28904066 Free PMC article. Highly Cited.
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Macrophage biology plays a central role during ionizing radiation-elicited tumor response. Qiuji Wu, Awatef Allouch, +3 authors, Isabelle Martins, Nazanine Modjtahedi, Eric Deutsch, Jean-Luc Perfettini. less Biomed J, 2017 Sep 19; 40(4). PMID: 28918908 Free PMC article. Review.
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Nanomaterials for cancer immunotherapy. Wantong Song, Sara N Musetti, Leaf Huang. Biomaterials, 2017 Sep 30; 148. PMID: 28961532 Free PMC article. Review.
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Improving radiotherapy in cancer treatment: Promises and challenges. Helen H W Chen, Macus Tien Kuo. Oncotarget, 2017 Oct 06; 8(37). PMID: 28977985 Free PMC article. Review.
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A regulatory role for the co-chaperone FKBP51s in PD-L1 expression in glioma. Paolo D'Arrigo, Michele Russo, +10 authors, Anna Rea, Martina Tufano, Elia Guadagno, Maria Laura Del Basso De Caro, Roberto Pacelli, Felix Hausch, Stefania Staibano, Gennaro Ilardi, Silvia Parisi, Maria Fiammetta Romano, Simona Romano. less Oncotarget, 2017 Oct 06; 8(40). PMID: 28978117 Free PMC article.
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Immune recognition of irradiated cancer cells. Erik Wennerberg, Claire Vanpouille-Box, +3 authors, Sophia Bornstein, Takahiro Yamazaki, Sandra Demaria, Lorenzo Galluzzi. less Immunol Rev, 2017 Oct 14; 280(1). PMID: 29027232 Free PMC article. Review.
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The anti-PD-1 era - an opportunity to enhance radiotherapy for patients with bladder cancer. Richard C Walshaw, Jamie Honeychurch, Timothy M Illidge, Ananya Choudhury. Nat Rev Urol, 2017 Nov 02; 15(4). PMID: 29089607 Review.
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Pembrolizumab for treatment of advanced gastric and gastroesophageal junction adenocarcinoma. Smita S Joshi, Steven B Maron, Daniel V Catenacci. Future Oncol, 2017 Nov 03; 14(5). PMID: 29094609 Free PMC article. Review.
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Radiotherapy prolongs the survival of advanced non-small-cell lung cancer patients undergone to an immune-modulating treatment with dose-fractioned cisplatin and metronomic etoposide and bevacizumab (mPEBev). Pierpaolo Pastina, Valerio Nardone, +15 authors, Cirino Botta, Stefania Croci, Paolo Tini, Giuseppe Battaglia, Veronica Ricci, Maria Grazia Cusi, Claudia Gandolfo, Gabriella Misso, Silvia Zappavigna, Michele Caraglia, Antonio Giordano, Donatella Aldinucci, Pierfrancesco Tassone, Pierosandro Tagliaferri, Luigi Pirtoli, Pierpaolo Correale. less Oncotarget, 2017 Nov 05; 8(44). PMID: 29100279 Free PMC article.
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Radiation alters PD-L1/NKG2D ligand levels in lung cancer cells and leads to immune escape from NK cell cytotoxicity via IL-6-MEK/Erk signaling pathway. Ming Jing Shen, Li Jun Xu, +5 authors, Li Yang, Ying Tsai, Peter C Keng, Yongbing Chen, Soo Ok Lee, Yuhchyau Chen. less Oncotarget, 2017 Nov 09; 8(46). PMID: 29113321 Free PMC article.
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Abscopal effect in recurrent colorectal cancer treated with carbon-ion radiation therapy: 2 case reports. Daniel K Ebner, Tadashi Kamada, Shigeru Yamada. Adv Radiat Oncol, 2017 Nov 09; 2(3). PMID: 29114600 Free PMC article.
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Blocking C5aR signaling promotes the anti-tumor efficacy of PD-1/PD-L1 blockade. Haoran Zha, Xiao Han, +5 authors, Ying Zhu, Fei Yang, Yongsheng Li, Qijing Li, Bo Guo, Bo Zhu. less Oncoimmunology, 2017 Nov 11; 6(10). PMID: 29123963 Free PMC article.
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Ionizing radiation sensitizes tumors to PD-L1 immune checkpoint blockade in orthotopic murine head and neck squamous cell carcinoma. Ayman Oweida, Shelby Lennon, +11 authors, Dylan Calame, Sean Korpela, Shilpa Bhatia, Jaspreet Sharma, Caleb Graham, David Binder, Natalie Serkova, David Raben, Lynn Heasley, Eric Clambey, Raphael Nemenoff, Sana D Karam. less Oncoimmunology, 2017 Nov 11; 6(10). PMID: 29123967 Free PMC article.
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Imaging PD-L1 Expression with ImmunoPET. Charles Truillet, Hsueh Ling J Oh, +19 authors, Siok Ping Yeo, Chia-Yin Lee, Loc T Huynh, Junnian Wei, Matthew F L Parker, Collin Blakely, Natalia Sevillano, Yung-Hua Wang, Yuqin S Shen, Victor Olivas, Khaled M Jami, Anna Moroz, Benoit Jego, Emilie Jaumain, Lawrence Fong, Charles S Craik, Albert J Chang, Trever G Bivona, Cheng-I Wang, Michael J Evans. less Bioconjug Chem, 2017 Nov 11; 29(1). PMID: 29125731 Free PMC article.
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Cure in Advanced Renal Cell Cancer: Is It an Achievable Goal? Dhanusha Sabanathan, John J Park, +3 authors, Manuel Marquez, Louise Francisco, Natalie Byrne, Howard Gurney. less Oncologist, 2017 Nov 18; 22(12). PMID: 29146617 Free PMC article.
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Radiation therapy-induced metastasis: radiobiology and clinical implications. Benjamin J Blyth, Aidan J Cole, Michael P MacManus, Olga A Martin. Clin Exp Metastasis, 2017 Nov 22; 35(4). PMID: 29159430 Review.
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Decreased Survival After Combining Thoracic Irradiation and an Anti-PD-1 Antibody Correlated With Increased T-cell Infiltration Into Cardiac and Lung Tissues. Carey J Myers, Bo Lu. Int J Radiat Oncol Biol Phys, 2017 Nov 23; 99(5). PMID: 29165283 Free PMC article.
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DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells. Hiro Sato, Atsuko Niimi, +14 authors, Takaaki Yasuhara, Tiara Bunga Mayang Permata, Yoshihiko Hagiwara, Mayu Isono, Endang Nuryadi, Ryota Sekine, Takahiro Oike, Sangeeta Kakoti, Yuya Yoshimoto, Kathryn D Held, Yoshiyuki Suzuki, Koji Kono, Kiyoshi Miyagawa, Takashi Nakano, Atsushi Shibata. less Nat Commun, 2017 Nov 25; 8(1). PMID: 29170499 Free PMC article. Highly Cited.
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Therapeutic Implications of the Genetic Landscape of Head and Neck Cancer. Janice Cho, Daniel E Johnson, Jennifer R Grandis. Semin Radiat Oncol, 2017 Nov 28; 28(1). PMID: 29173752 Free PMC article. Review.
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Potential role of radiation therapy in augmenting the activity of immunotherapy for gynecologic cancers. Christina H Son, Gini F Fleming, John W Moroney. Cancer Manag Res, 2017 Dec 01; 9. PMID: 29184441 Free PMC article. Review.
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Future cancer research priorities in the USA: a Lancet Oncology Commission. Elizabeth M Jaffee, Chi Van Dang, +51 authors, David B Agus, Brian M Alexander, Kenneth C Anderson, Alan Ashworth, Anna D Barker, Roshan Bastani, Sangeeta Bhatia, Jeffrey A Bluestone, Otis Brawley, Atul J Butte, Daniel G Coit, Nancy E Davidson, Mark Davis, Ronald A DePinho, Robert B Diasio, Giulio Draetta, A Lindsay Frazier, Andrew Futreal, Sam S Gambhir, Patricia A Ganz, Levi Garraway, Stanton Gerson, Sumit Gupta, James Heath, Ruth I Hoffman, Cliff Hudis, Chanita Hughes-Halbert, Ramy Ibrahim, Hossein Jadvar, Brian Kavanagh, Rick Kittles, Quynh-Thu Le, Scott M Lippman, David Mankoff, Elaine R Mardis, Deborah K Mayer, Kelly McMasters, Neal J Meropol, Beverly Mitchell, Peter Naredi, Dean Ornish, Timothy M Pawlik, Jeffrey Peppercorn, Martin G Pomper, Derek Raghavan, Christine Ritchie, Sally W Schwarz, Richard Sullivan, Richard Wahl, Jedd D Wolchok, Sandra L Wong, Alfred Yung. less Lancet Oncol, 2017 Dec 07; 18(11). PMID: 29208398 Free PMC article. Review.
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Detection of programmed death ligand 1 protein and CD8+ lymphocyte infiltration in plurihormonal pituitary adenomas: A case report and review of the literatures. Pengfei Wang, Tingjian Wang, +3 authors, Yakun Yang, Chunjiang Yu, Ning Liu, Changxiang Yan. less Medicine (Baltimore), 2017 Dec 17; 96(49). PMID: 29245312 Free PMC article. Review.
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Radiation enhanced the local and distant anti-tumor efficacy in dual immune checkpoint blockade therapy in osteosarcoma. Yutaka Takahashi, Tomohiro Yasui, +7 authors, Keisuke Tamari, Kazumasa Minami, Keisuke Otani, Fumiaki Isohashi, Yuji Seo, Ryosuke Kambe, Masahiko Koizumi, Kazuhiko Ogawa. less PLoS One, 2017 Dec 19; 12(12). PMID: 29253865 Free PMC article.
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Emerging biomarkers for the combination of radiotherapy and immune checkpoint blockers. Claire Lhuillier, Claire Vanpouille-Box, +2 authors, Lorenzo Galluzzi, Silvia Chiara Formenti, Sandra Demaria. less Semin Cancer Biol, 2017 Dec 21; 52(Pt 2). PMID: 29258856 Free PMC article. Review.
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Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution. Mirjana Efremova, Dietmar Rieder, +8 authors, Victoria Klepsch, Pornpimol Charoentong, Francesca Finotello, Hubert Hackl, Natascha Hermann-Kleiter, Martin Löwer, Gottfried Baier, Anne Krogsdam, Zlatko Trajanoski. less Nat Commun, 2018 Jan 04; 9(1). PMID: 29296022 Free PMC article. Highly Cited.
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Inhibition of PI4K IIIα radiosensitizes in human tumor xenograft and immune-competent syngeneic murine tumor model. Younghee Park, Ji Min Park, +2 authors, Dan Hyo Kim, Jeanny Kwon, In Ah Kim. less Oncotarget, 2018 Jan 05; 8(66). PMID: 29299156 Free PMC article.
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Analysis of the immune infiltrate in undifferentiated pleomorphic sarcoma of the extremity and trunk in response to radiotherapy: Rationale for combination neoadjuvant immune checkpoint inhibition and radiotherapy. Emily Z Keung, Jen-Wei Tsai, +10 authors, Ali M Ali, Janice N Cormier, Andrew J Bishop, B Ashleigh Guadagnolo, Keila E Torres, Neeta Somaiah, Kelly K Hunt, Jennifer A Wargo, Alexander J Lazar, Wei-Lien Wang, Christina L Roland. less Oncoimmunology, 2018 Jan 09; 7(2). PMID: 29308306 Free PMC article.
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Local Radiotherapy Affects Drug Pharmacokinetics-Exploration of a Neglected but Significant Uncertainty of Cancer Therapy. Yu-Jen Chen, Tung-Hu Tsai, Li-Ying Wang, Chen-Hsi Hsieh. Technol Cancer Res Treat, 2018 Jan 16; 16(6). PMID: 29332468 Free PMC article. Review.
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Dinaciclib induces immunogenic cell death and enhances anti-PD1-mediated tumor suppression. Dewan Md Sakib Hossain, Sarah Javaid, +8 authors, Mingmei Cai, Chunsheng Zhang, Anandi Sawant, Marlene Hinton, Manjiri Sathe, Jeff Grein, Wendy Blumenschein, Elaine M Pinheiro, Alissa Chackerian. less J Clin Invest, 2018 Jan 18; 128(2). PMID: 29337311 Free PMC article.
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CNS side effects of immune checkpoint inhibitors: preclinical models, genetics and multimodality therapy. Gwendolyn J McGinnis, Jacob Raber. Immunotherapy, 2018 Jan 18; 9(11). PMID: 29338610 Free PMC article. Review.
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Adoptive immunotherapy shows encouraging benefit on non-small cell lung cancer: a systematic review and meta-analysis. Binghao Zhao, Wenxiong Zhang, +2 authors, Dongliang Yu, Jianjun Xu, Yiping Wei. less Oncotarget, 2018 Jan 20; 8(68). PMID: 29348890 Free PMC article.
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Microsatellite stability and mismatch repair proficiency in nasopharyngeal carcinoma may not predict programmed death-1 blockade resistance. Xiyi Liao, Liang Zhao, +5 authors, Sangang Wu, Hua Zheng, Haojun Chen, Huan Zhang, ZiJing Wang, Qin Lin. less Oncotarget, 2018 Jan 20; 8(68). PMID: 29348907 Free PMC article.
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[Durvalumab improves prognosis of stage III non-small-cell lung cancer after definitive chemoradiotherapy]. Markus Hecht, Udo S Gaipl, Rainer Fietkau. Strahlenther Onkol, 2018 Jan 28; 194(3). PMID: 29374302
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Current perspectives on bone metastases in castrate-resistant prostate cancer. Christopher Logothetis, Michael J Morris, Robert Den, Robert E Coleman. Cancer Metastasis Rev, 2018 Jan 31; 37(1). PMID: 29380085 Free PMC article. Review.
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Radiation effects on antitumor immune responses: current perspectives and challenges. Thomas Walle, Rafael Martinez Monge, +3 authors, Adelheid Cerwenka, Daniel Ajona, Ignacio Melero, Fernando Lecanda. less Ther Adv Med Oncol, 2018 Feb 01; 10. PMID: 29383033 Free PMC article. Highly Cited. Review.
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Expected Paradigm Shift in Brain Metastases Therapy-Immune Checkpoint Inhibitors. Vishal Jindal, Sorab Gupta. Mol Neurobiol, 2018 Feb 01; 55(8). PMID: 29383686 Review.
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Recent advances in the biology and treatment of brain metastases of non-small cell lung cancer: summary of a multidisciplinary roundtable discussion. Matthias Preusser, Frank Winkler, +5 authors, Manuel Valiente, Christian Manegold, Elizabeth Moyal, Georg Widhalm, Jörg-Christian Tonn, Christoph Zielinski. less ESMO Open, 2018 Feb 02; 3(1). PMID: 29387475 Free PMC article. Review.
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PD-1 blockade reverses adaptive immune resistance induced by high-dose hypofractionated but not low-dose daily fractionated radiation. Megan Morisada, Paul E Clavijo, +7 authors, Ellen Moore, Lillian Sun, Michael Chamberlin, Carter Van Waes, James W Hodge, James B Mitchell, Jay Friedman, Clint T Allen. less Oncoimmunology, 2018 Feb 06; 7(3). PMID: 29399393 Free PMC article.
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Antibody targeting of phosphatidylserine for the detection and immunotherapy of cancer. Olivier Belzile, Xianming Huang, +4 authors, Jian Gong, Jay Carlson, Alan J Schroit, Rolf A Brekken, Bruce D Freimark. less Immunotargets Ther, 2018 Feb 09; 7. PMID: 29417044 Free PMC article. Review.
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Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors. Jason J Luke, Jeffrey M Lemons, +17 authors, Theodore G Karrison, Sean P Pitroda, James M Melotek, Yuanyuan Zha, Hania A Al-Hallaq, Ainhoa Arina, Nikolai N Khodarev, Linda Janisch, Paul Chang, Jyoti D Patel, Gini F Fleming, John Moroney, Manish R Sharma, Julia R White, Mark J Ratain, Thomas F Gajewski, Ralph R Weichselbaum, Steven J Chmura. less J Clin Oncol, 2018 Feb 14; 36(16). PMID: 29437535 Free PMC article. Highly Cited.
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Using immunotherapy to boost the abscopal effect. Wilfred Ngwa, Omoruyi Credit Irabor, +3 authors, Jonathan D Schoenfeld, Jürgen Hesser, Sandra Demaria, Silvia C Formenti. less Nat Rev Cancer, 2018 Feb 17; 18(5). PMID: 29449659 Free PMC article. Highly Cited. Review.
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Exploring the rationale for combining ionizing radiation and immune checkpoint blockade in head and neck cancer. Megan Morisada, Michael Chamberlin, Clint Allen. Head Neck, 2018 Feb 21; 40(6). PMID: 29461655 Free PMC article. Review.
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The Abscopal Effect in the Era of Cancer Immunotherapy: a Spontaneous Synergism Boosting Anti-tumor Immunity? Zuzana Hlavata, Cinzia Solinas, +4 authors, Pushpamali De Silva, Michele Porcu, Luca Saba, Karen Willard-Gallo, Mario Scartozzi. less Target Oncol, 2018 Feb 23; 13(2). PMID: 29470785
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Radiation and PD-(L)1 treatment combinations: immune response and dose optimization via a predictive systems model. Yuri Kosinsky, Simon J Dovedi, +6 authors, Kirill Peskov, Veronika Voronova, Lulu Chu, Helen Tomkinson, Nidal Al-Huniti, Donald R Stanski, Gabriel Helmlinger. less J Immunother Cancer, 2018 Mar 01; 6(1). PMID: 29486799 Free PMC article.
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IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma. Erik Ladomersky, Lijie Zhai, +18 authors, Alicia Lenzen, Kristen L Lauing, Jun Qian, Denise M Scholtens, Galina Gritsina, Xuebing Sun, Ye Liu, Fenglong Yu, Wenfeng Gong, Yong Liu, Beibei Jiang, Tristin Tang, Ricky Patel, Leonidas C Platanias, C David James, Roger Stupp, Rimas V Lukas, David C Binder, Derek A Wainwright. less Clin Cancer Res, 2018 Mar 04; 24(11). PMID: 29500275 Free PMC article. Highly Cited.
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Immune modulatory effects of radiotherapy as basis for well-reasoned radioimmunotherapies. Michael Rückert, Lisa Deloch, +3 authors, Rainer Fietkau, Benjamin Frey, Markus Hecht, Udo S Gaipl. less Strahlenther Onkol, 2018 Mar 04; 194(6). PMID: 29500551 Highly Cited. Review.
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Immunotherapy for Head and Neck Squamous Cell Carcinoma. Jessica Moskovitz, Jennifer Moy, Robert L Ferris. Curr Oncol Rep, 2018 Mar 05; 20(2). PMID: 29502288 Free PMC article. Review.
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Immune checkpoint inhibitors in neuroendocrine tumors: A single institution experience with review of literature. Aman Chauhan, Millicent Horn, +4 authors, Gray Magee, Kurt Hodges, Mark Evers, Susanne Arnold, Lowell Anthony. less Oncotarget, 2018 Mar 07; 9(10). PMID: 29507655 Free PMC article.
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Engineering Vaccines to Reprogram Immunity against Head and Neck Cancer. Y S Tan, K Sansanaphongpricha, +3 authors, M E P Prince, D Sun, G T Wolf, Y L Lei. less J Dent Res, 2018 Mar 14; 97(6). PMID: 29533731 Free PMC article. Review.
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Combined modality radiation therapy promotes tolerogenic myeloid cell populations and STAT3-related gene expression in head and neck cancer patients. Sagus Sampath, Haejung Won, +6 authors, Erminia Massarelli, Min Li, Paul Frankel, Nayana Vora, Lalit Vora, Ellie Maghami, Marcin Kortylewski. less Oncotarget, 2018 Mar 16; 9(13). PMID: 29541413 Free PMC article.
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The Impact of Radiation on the Tumor Microenvironment: Effect of Dose and Fractionation Schedules. Kimberly M Arnold, Nicole J Flynn, +5 authors, Adam Raben, Lindsay Romak, Yan Yu, Adam P Dicker, Firas Mourtada, Jennifer Sims-Mourtada. less Cancer Growth Metastasis, 2018 Mar 20; 11. PMID: 29551910 Free PMC article. Review.
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Combining Immunotherapy and Radiotherapy for Cancer Treatment: Current Challenges and Future Directions. Yifan Wang, Weiye Deng, +4 authors, Nan Li, Shinya Neri, Amrish Sharma, Wen Jiang, Steven H Lin. less Front Pharmacol, 2018 Mar 21; 9. PMID: 29556198 Free PMC article. Highly Cited. Review.
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Harnessing and Optimizing the Interplay between Immunotherapy and Radiotherapy to Improve Survival Outcomes. Kalpana Mujoo, Clayton R Hunt, +5 authors, Raj K Pandita, Mauro Ferrari, Sunil Krishnan, John P Cooke, Stephen Hahn, Tej K Pandita. less Mol Cancer Res, 2018 Mar 30; 16(8). PMID: 29592896 Free PMC article. Review.
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Immune checkpoint inhibitors in small cell lung cancer. Suchita Pakkala, Taofeek K Owonikoko. J Thorac Dis, 2018 Mar 30; 10(Suppl 3). PMID: 29593891 Free PMC article. Review.
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Anti PD-L1 DUrvalumab combined with Cetuximab and RadiOtherapy in locally advanced squamous cell carcinoma of the head and neck: A phase I/II study (DUCRO). Pierluigi Bonomo, Isacco Desideri, +7 authors, Mauro Loi, Monica Mangoni, Mariangela Sottili, Livia Marrazzo, Cinzia Talamonti, Daniela Greto, Stefania Pallotta, Lorenzo Livi. less Clin Transl Radiat Oncol, 2018 Mar 30; 9. PMID: 29594250 Free PMC article.
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Radiotherapy-induced anti-tumor immune response and immune-related adverse events in a case of recurrent nasopharyngeal carcinoma undergoing anti-PD-1 immunotherapy. T Finazzi, T Rordorf, +3 authors, K Ikenberg, G F Huber, M Guckenberger, H I Garcia Schueler. less BMC Cancer, 2018 Apr 08; 18(1). PMID: 29625593 Free PMC article.
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Emerging Concepts for Immune Checkpoint Blockade-Based Combination Therapies. Roberta Zappasodi, Taha Merghoub, Jedd D Wolchok. Cancer Cell, 2018 Apr 11; 33(4). PMID: 29634946 Free PMC article. Highly Cited. Review.
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Beyond checkpoint inhibition - Immunotherapeutical strategies in combination with radiation. F Eckert, U S Gaipl, +4 authors, G Niedermann, M Hettich, K Schilbach, S M Huber, D Zips. less Clin Transl Radiat Oncol, 2017 Feb 04; 2. PMID: 29657997 Free PMC article. Review.
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The expression profile of PD-L1 and CD8+ lymphocyte in pituitary adenomas indicating for immunotherapy. Peng-Fei Wang, Ting-Jian Wang, +4 authors, Ya-Kun Yang, Kun Yao, Zhuo Li, Yan Michael Li, Chang-Xiang Yan. less J Neurooncol, 2018 Apr 24; 139(1). PMID: 29680903
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Immunotherapy after chemoradiotherapy in stage III non-small cell lung cancer: a new standard of care? Anna W Chalmers, Shiven B Patel, Wallace Akerley. J Thorac Dis, 2018 May 01; 10(3). PMID: 29707266 Free PMC article.
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PD-L1 expression in medulloblastoma: an evaluation by subgroup. Allison M Martin, Christopher J Nirschl, +19 authors, Magda J Polanczyk, W Robert Bell, Thomas R Nirschl, Sarah Harris-Bookman, Jillian Phallen, Jessica Hicks, Daniel Martinez, Aleksandra Ogurtsova, Haiying Xu, Lisa M Sullivan, Alan K Meeker, Eric H Raabe, Kenneth J Cohen, Charles G Eberhart, Peter C Burger, Mariarita Santi, Janis M Taube, Drew M Pardoll, Charles G Drake, Michael Lim. less Oncotarget, 2018 May 04; 9(27). PMID: 29721192 Free PMC article.
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Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity. Marka R Crittenden, Lauren Zebertavage, +7 authors, Gwen Kramer, Shelly Bambina, David Friedman, Victoria Troesch, Tiffany Blair, Jason R Baird, Alejandro Alice, Michael J Gough. less Sci Rep, 2018 May 05; 8(1). PMID: 29725089 Free PMC article.
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Precision radiotherapy for patients with locally advanced non-small cell lung cancer in the era of immunotherapy and precision medicine. Hidehito Horinouch. Transl Lung Cancer Res, 2018 May 22; 7(Suppl 2). PMID: 29780707 Free PMC article.
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Radiation Followed by OX40 Stimulation Drives Local and Abscopal Antitumor Effects in an Anti-PD1-Resistant Lung Tumor Model. Sharareh Niknam, Hampartsoum B Barsoumian, +15 authors, Jonathan E Schoenhals, Heather L Jackson, Niranjan Yanamandra, Mauricio S Caetano, Ailin Li, Ahmed I Younes, Alexandra Cadena, Taylor R Cushman, Joe Y Chang, Quynh N Nguyen, Daniel R Gomez, Adi Diab, John V Heymach, Patrick Hwu, Maria Angelica Cortez, James W Welsh. less Clin Cancer Res, 2018 May 23; 24(22). PMID: 29784675 Free PMC article.
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Bacillus Calmette-Guérin and anti-PD-L1 combination therapy boosts immune response against bladder cancer. Yonghua Wang, Jing Liu, +6 authors, Xuecheng Yang, Yanan Liu, Yong Liu, Yanjiang Li, Lijiang Sun, Xiaokun Yang, Haitao Niu. less Onco Targets Ther, 2018 May 31; 11. PMID: 29844686 Free PMC article.
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Durvalumab after chemo-radiotherapy in stage III non-small cell lung cancer. Jaseela Chiramel, Rebecca Tay, Raffaele Califano. J Thorac Dis, 2018 Jun 01; 10(Suppl 9). PMID: 29850180 Free PMC article.
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Durvalumab after chemoradiotherapy in stage III non-small cell lung cancer. Pascale Tomasini, Laurent Greillier, +2 authors, Arnaud Boyer, Arnaud Jeanson, Fabrice Barlesi. less J Thorac Dis, 2018 Jun 01; 10(Suppl 9). PMID: 29850182 Free PMC article.
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Future of anti-PD-1/PD-L1 applications: Combinations with other therapeutic regimens. Mengjia Song, Xinfeng Chen, Liping Wang, Yi Zhang. Chin J Cancer Res, 2018 Jun 05; 30(2). PMID: 29861603 Free PMC article.
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The Evolution of Radiation Therapy in Metastatic Breast Cancer: From Local Therapy to Systemic Agent. Jessica M S Jutzy, Jeffrey M Lemons, Jason J Luke, Steven J Chmura. Int J Breast Cancer, 2018 Jun 05; 2018. PMID: 29862083 Free PMC article. Review.
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Radiation therapy and PD-1/PD-L1 blockade: the clinical development of an evolving anticancer combination. Jun Gong, Thang Q Le, +2 authors, Erminia Massarelli, Andrew E Hendifar, Richard Tuli. less J Immunother Cancer, 2018 Jun 06; 6(1). PMID: 29866197 Free PMC article. Review.
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Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap. Wantong Song, Limei Shen, +7 authors, Ying Wang, Qi Liu, Tyler J Goodwin, Jingjing Li, Olekasandra Dorosheva, Tianzhou Liu, Rihe Liu, Leaf Huang. less Nat Commun, 2018 Jun 10; 9(1). PMID: 29884866 Free PMC article. Highly Cited.
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Tumor molecular profiling of responders and non-responders following pembrolizumab monotherapy in chemotherapy resistant advanced cervical cancer. N Y L Ngoi, V Heong, +9 authors, X W Lee, Y Q Huang, Y L Thian, B A Choo, D Lim, Y W Lim, S E Lim, A Ilancheran, R Soong, D S P Tan. less Gynecol Oncol Rep, 2018 Jun 13; 24. PMID: 29892689 Free PMC article.
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Safety and efficacy of concurrent immune checkpoint inhibitors and hypofractionated body radiotherapy. Osama Mohamad, Alberto Diaz de Leon, +17 authors, Samuel Schroeder, Andrew Leiker, Alana Christie, Elizabeth Zhang-Velten, Lakshya Trivedi, Saad Khan, Neil B Desai, Aaron Laine, Kevin Albuquerque, Puneeth Iyengar, Yull Arriaga, Kevin Courtney, David E Gerber, Hans Hammers, Hak Choy, Robert Timmerman, James Brugarolas, Raquibul Hannan. less Oncoimmunology, 2018 Jun 15; 7(7). PMID: 29900043 Free PMC article.
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Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy. Kaiyuan Ni, Guangxu Lan, +7 authors, Christina Chan, Bryan Quigley, Kuangda Lu, Theint Aung, Nining Guo, Patrick La Riviere, Ralph R Weichselbaum, Wenbin Lin. less Nat Commun, 2018 Jun 17; 9(1). PMID: 29907739 Free PMC article.
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Immune checkpoint inhibitors and radiosurgery for newly diagnosed melanoma brain metastases. Tyler P Robin, Robert E Breeze, +12 authors, Derek E Smith, Chad G Rusthoven, Karl D Lewis, Rene Gonzalez, Amanda Brill, Robin Saiki, Kelly Stuhr, Laurie E Gaspar, Sana D Karam, David Raben, Brian D Kavanagh, Sameer K Nath, Arthur K Liu. less J Neurooncol, 2018 Jun 18; 140(1). PMID: 29909499 Free PMC article.
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Is there a room for immune checkpoint inhibitors in early stage non-small cell lung cancer? Elisa Gobbini, Matteo Giaj Levra. J Thorac Dis, 2018 Jun 29; 10(Suppl 13). PMID: 29951294 Free PMC article. Review.
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Combining immunotherapy and radiotherapy in lung cancer. Neeraj Bhalla, Rachel Brooker, Michael Brada. J Thorac Dis, 2018 Jun 29; 10(Suppl 13). PMID: 29951296 Free PMC article. Review.
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Shining light on advanced NSCLC in 2017: combining immune checkpoint inhibitors. Meng Qiao, Tao Jiang, Caicun Zhou. J Thorac Dis, 2018 Jun 29; 10(Suppl 13). PMID: 29951304 Free PMC article. Review.
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ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiation. Frank P Vendetti, Pooja Karukonda, +13 authors, David A Clump, Troy Teo, Ronald Lalonde, Katriana Nugent, Matthew Ballew, Brian F Kiesel, Jan H Beumer, Saumendra N Sarkar, Thomas P Conrads, Mark J O'Connor, Robert L Ferris, Phuoc T Tran, Greg M Delgoffe, Christopher J Bakkenist. less J Clin Invest, 2018 Jun 29; 128(9). PMID: 29952768 Free PMC article. Highly Cited.
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Biological effects of radiation on cancer cells. Jin-Song Wang, Hai-Juan Wang, Hai-Li Qian. Mil Med Res, 2018 Jul 01; 5(1). PMID: 29958545 Free PMC article. Review.
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Combined VLA-4-Targeted Radionuclide Therapy and Immunotherapy in a Mouse Model of Melanoma. Jaeyeon Choi, Wissam Beaino, +5 authors, Ronald J Fecek, Kellsye P L Fabian, Charles M Laymon, Brenda F Kurland, Walter J Storkus, Carolyn J Anderson. less J Nucl Med, 2018 Jul 01; 59(12). PMID: 29959213 Free PMC article.
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Lymphocyte-Activation Gene-3 Expression and Prognostic Value in Neoadjuvant-Treated Triple-Negative Breast Cancer. Yunxuan Wang, Tieying Dong, +3 authors, Qijia Xuan, Hong Zhao, Ling Qin, Qingyuan Zhang. less J Breast Cancer, 2018 Jul 03; 21(2). PMID: 29963107 Free PMC article.
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Personalizing Radiation Treatment Delivery in the Management of Breast Cancer. Kamran A Ahmed, G Daniel Grass, +7 authors, Amber G Orman, Casey Liveringhouse, Michael E Montejo, Hatem H Soliman, Heather S Han, Brian J Czerniecki, Javier F Torres-Roca, Roberto Diaz. less Int J Breast Cancer, 2018 Jul 10; 2018. PMID: 29984003 Free PMC article. Review.
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The influence of radiation in the context of developing combination immunotherapies in cancer. Jamie Honeychurch, Timothy M Illidge. Ther Adv Vaccines Immunother, 2018 Jul 13; 5(6). PMID: 29998216 Free PMC article. Review.
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Key mechanisms involved in ionizing radiation-induced systemic effects. A current review. Ifigeneia V Mavragani, Danae A Laskaratou, +4 authors, Benjamin Frey, Serge M Candéias, Udo S Gaipl, Katalin Lumniczky, Alexandros G Georgakilas. less Toxicol Res (Camb), 2015 Aug 11; 5(1). PMID: 30090323 Free PMC article. Review.
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Inhibition of ATR downregulates PD-L1 and sensitizes tumor cells to T cell-mediated killing. Lin-Lin Sun, Ri-Yao Yang, +8 authors, Chia-Wei Li, Mei-Kuang Chen, Bin Shao, Jung-Mao Hsu, Li-Chuan Chan, Yi Yang, Jennifer L Hsu, Yun-Ju Lai, Mien-Chie Hung. less Am J Cancer Res, 2018 Aug 11; 8(7). PMID: 30094103 Free PMC article.
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Combining Immune Checkpoint Inhibitors With Conventional Cancer Therapy. Yiyi Yan, Anagha Bangalore Kumar, +4 authors, Heidi Finnes, Svetomir N Markovic, Sean Park, Roxana S Dronca, Haidong Dong. less Front Immunol, 2018 Aug 14; 9. PMID: 30100909 Free PMC article. Highly Cited. Review.
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Myeloid-Derived Suppressor Cells as a Regulator of Immunity in Organ Transplantation. Tsukasa Nakamura, Hidetaka Ushigome. Int J Mol Sci, 2018 Aug 15; 19(8). PMID: 30103447 Free PMC article. Review.
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The Expanding Role of Radiosurgery for Brain Metastases. Mark O'Beirn, Helen Benghiat, +5 authors, Sara Meade, Geoff Heyes, Vijay Sawlani, Anthony Kong, Andrew Hartley, Paul Sanghera. less Medicines (Basel), 2018 Aug 17; 5(3). PMID: 30110927 Free PMC article. Review.
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Abscopal effect of radiotherapy combined with immune checkpoint inhibitors. Yang Liu, Yinping Dong, +3 authors, Li Kong, Fang Shi, Hui Zhu, Jinming Yu. less J Hematol Oncol, 2018 Aug 18; 11(1). PMID: 30115069 Free PMC article. Highly Cited. Review.
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Immune Checkpoint Inhibition for Pancreatic Ductal Adenocarcinoma: Current Limitations and Future Options. Derya Kabacaoglu, Katrin J Ciecielski, Dietrich A Ruess, Hana Algül. Front Immunol, 2018 Aug 31; 9. PMID: 30158932 Free PMC article. Review.
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Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy. Yuzhu Hou, Hua Liang, +10 authors, Enyu Rao, Wenxin Zheng, Xiaona Huang, Liufu Deng, Yuan Zhang, Xinshuang Yu, Meng Xu, Helena Mauceri, Ainhoa Arina, Ralph R Weichselbaum, Yang-Xin Fu. less Immunity, 2018 Sep 02; 49(3). PMID: 30170810 Free PMC article.
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Activation of immune responses in patients with relapsed-metastatic head and neck cancer (CONFRONT phase I-II trial): Multimodality immunotherapy with avelumab, short-course radiotherapy, and cyclophosphamide. Marco C Merlano, Anna M Merlotti, +9 authors, Lisa Licitra, Nerina Denaro, Elena Fea, Danilo Galizia, Massimo Di Maio, Claudia Fruttero, Paola Curcio, Stefania Vecchio, Elvio G Russi, Renzo Corvò. less Clin Transl Radiat Oncol, 2018 Sep 07; 12. PMID: 30186977 Free PMC article.
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Multi-institutional report on toxicities of concurrent nivolumab and radiation therapy. Neha P Amin, Maliha Zainib, +2 authors, Sean M Parker, Manuj Agarwal, Malcolm D Mattes. less Adv Radiat Oncol, 2018 Sep 12; 3(3). PMID: 30202808 Free PMC article.
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Robotic Stereotactic Radiosurgery in Melanoma Patients with Brain Metastases under Simultaneous Anti-PD-1 Treatment. Maike Trommer-Nestler, Simone Marnitz, +9 authors, Martin Kocher, Daniel Rueß, Max Schlaak, Sebastian Theurich, Michael von Bergwelt-Baildon, Janis Morgenthaler, Karolina Jablonska, Eren Celik, Maximilian I Ruge, Christian Baues. less Int J Mol Sci, 2018 Sep 13; 19(9). PMID: 30205431 Free PMC article.
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Advances in radiation therapy for thoracic malignancies. Charles B Simone, Shahed N Badiyan, Pranshu Mohindra. J Thorac Dis, 2018 Sep 13; 10(Suppl 21). PMID: 30206489 Free PMC article.
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Combining immunotherapy with radiation therapy in thoracic oncology. Shahed N Badiyan, Michael C Roach, +7 authors, Michael D Chuong, Stephanie R Rice, Nasarachi E Onyeuku, Jill Remick, Srinivas Chilukuri, Erica Glass, Pranshu Mohindra, Charles B Simone. less J Thorac Dis, 2018 Sep 13; 10(Suppl 21). PMID: 30206494 Free PMC article. Review.
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Long-term survival of locally advanced stage III non-small cell lung cancer patients treated with chemoradiotherapy and perspectives for the treatment with immunotherapy. Martina Vrankar, Karmen Stanic. Radiol Oncol, 2018 Sep 14; 52(3). PMID: 30210037 Free PMC article.
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Immune Checkpoint Inhibition in Head and Neck Cancer. Martin David Forster, Michael-John Devlin. Front Oncol, 2018 Sep 14; 8. PMID: 30211111 Free PMC article. Review.
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Turn Back the TIMe: Targeting Tumor Infiltrating Myeloid Cells to Revert Cancer Progression. Robin Maximilian Awad, Yannick De Vlaeminck, +2 authors, Johannes Maebe, Cleo Goyvaerts, Karine Breckpot. less Front Immunol, 2018 Sep 21; 9. PMID: 30233579 Free PMC article. Highly Cited. Review.
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Expression of PD-1 and PD-L1 increase in consecutive biopsies in patients with classical Hodgkin lymphoma. Peter Hollander, Rose-Marie Amini, +3 authors, Beatrice Ginman, Daniel Molin, Gunilla Enblad, Ingrid Glimelius. less PLoS One, 2018 Sep 28; 13(9). PMID: 30261066 Free PMC article.
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Liposomal Formulations to Modulate the Tumour Microenvironment and Antitumour Immune Response. Roger Gilabert-Oriol, Gemma M Ryan, +3 authors, Ada W Y Leung, Natalie S Firmino, Kevin L Bennewith, Marcel B Bally. less Int J Mol Sci, 2018 Sep 29; 19(10). PMID: 30261606 Free PMC article. Review.
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Biochemical Aspects of PD-L1 Regulation in Cancer Immunotherapy. Jinfang Zhang, Fabin Dang, Junming Ren, Wenyi Wei. Trends Biochem Sci, 2018 Oct 06; 43(12). PMID: 30287140 Free PMC article. Review.
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Prognostic Factors for Checkpoint Inhibitor Based Immunotherapy: An Update With New Evidences. Xinyu Yan, Shouyue Zhang, +3 authors, Yun Deng, Peiqi Wang, Qianqian Hou, Heng Xu. less Front Pharmacol, 2018 Oct 09; 9. PMID: 30294272 Free PMC article. Review.
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Accelerated, but not conventional, radiotherapy of murine B-cell lymphoma induces potent T cell-mediated remissions. Suparna Dutt, Michelle B Atallah, +7 authors, Yoshitaka Minamida, Alexander Filatenkov, Kent P Jensen, Bettina P Iliopoulou, Rasa Tamosiuniene, Jeffrey Waters, Edgar G Engleman, Samuel Strober. less Blood Adv, 2018 Oct 12; 2(19). PMID: 30301812 Free PMC article.
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Low PD-L1 Expression Strongly Correlates with Local Recurrence in Epstein-Barr Virus-Positive Nasopharyngeal Carcinoma after Radiation-Based Therapy. Yu-Jen Liu, Ngan-Ming Tsang, +4 authors, Chuen Hsueh, Chi-Ju Yeh, Shir-Hwa Ueng, Tong-Hong Wang, Wen-Yu Chuang. less Cancers (Basel), 2018 Oct 12; 10(10). PMID: 30304846 Free PMC article.
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Safety of combined PD-1 pathway inhibition and radiation therapy for non-small-cell lung cancer: A multicentric retrospective study from the GFPC. Paul Lesueur, Alexandre Escande, +9 authors, Juliette Thariat, Enora Vauléon, Isabelle Monnet, Alexis Cortot, Delphine Lerouge, Serge Danhier, Pascal Dô, Catherine Dubos-Arvis, Christos Chouaïd, Radj Gervais. less Cancer Med, 2018 Oct 13; 7(11). PMID: 30311424 Free PMC article.
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Immune Checkpoint Inhibitors for the Treatment of Central Nervous System (CNS) Metastatic Disease. Suneel D Kamath, Priya U Kumthekar. Front Oncol, 2018 Oct 16; 8. PMID: 30319977 Free PMC article. Review.
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Multimodal detection of PD-L1: reasonable biomarkers for immune checkpoint inhibitor. Qiao Yang, Zihan Xu, +3 authors, Linpeng Zheng, Luping Zhang, Qiai You, Jianguo Sun. less Am J Cancer Res, 2018 Oct 17; 8(9). PMID: 30323963 Free PMC article. Review.
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Methylseleninic Acid Sensitizes Ovarian Cancer Cells to T-Cell Mediated Killing by Decreasing PDL1 and VEGF Levels. Deepika Nair, Emelie Rådestad, +6 authors, Prajakta Khalkar, Nuria Diaz-Argelich, Axel Schröder, Charlotte Klynning, Johanna Ungerstedt, Michael Uhlin, Aristi P Fernandes. less Front Oncol, 2018 Oct 17; 8. PMID: 30324091 Free PMC article.
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The Role of Immunotherapy and Radiation Therapy in Tumor Chemosensitivity in Advanced Head and Neck Cancer. Saad O Atiq, Osman O Atiq, +5 authors, Mohammad O Atiq, Kara C Phillips, Blake B Jacks, Mauricio Moreno, Sanjay Maraboyina, Omar T Atiq. less Am J Case Rep, 2018 Oct 20; 19. PMID: 30333474 Free PMC article.
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Clinical significance of programmed death 1 ligand-1 (CD274/PD-L1) and intra-tumoral CD8+ T-cell infiltration in stage II-III colorectal cancer. Chih-Yang Huang, Shu-Fen Chiang, +4 authors, Tao-Wei Ke, Tsung-Wei Chen, Ying-Shu You, William Tzu-Liang Chen, K S Clifford Chao. less Sci Rep, 2018 Oct 26; 8(1). PMID: 30353144 Free PMC article.
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[Predictive value of PD-L1 diagnostics]. H-U Schildhaus. Pathologe, 2018 Oct 28; 39(6). PMID: 30367225 Review.
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Generating antitumor immunity by targeted radiation therapy: Role of dose and fractionation. Eric C Ko, Kimberly Thomas Benjamin, Silvia C Formenti. Adv Radiat Oncol, 2018 Oct 30; 3(4). PMID: 30370347 Free PMC article. Review.
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Role of noninvasive molecular imaging in determining response. Ariel E Marciscano, Daniel L J Thorek. Adv Radiat Oncol, 2018 Oct 30; 3(4). PMID: 30370353 Free PMC article. Review.
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Exploring the Concept of Radiation "Booster Shot" in Combination with an Anti-PD-L1 mAb to Enhance Anti-Tumor Immune Effects in Mouse Pancreas Tumors. Michael Chuong, Elizabeth T Chang, +4 authors, Eun Yong Choi, Javed Mahmood, Rena G Lapidus, Eduardo Davila, France Carrier. less J Clin Oncol Res, 2017 Jan 01; 5(2). PMID: 30417086 Free PMC article.
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Radiation combined with macrophage depletion promotes adaptive immunity and potentiates checkpoint blockade. Keaton I Jones, Jiske Tiersma, +4 authors, Arseniy E Yuzhalin, Alex N Gordon-Weeks, Jon Buzzelli, Jae Hong Im, Ruth J Muschel. less EMBO Mol Med, 2018 Nov 18; 10(12). PMID: 30442705 Free PMC article.
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Radiation therapy and immunotherapy-a potential combination in cancer treatment. N Asna, A Livoff, +4 authors, R Batash, R Debbi, P Schaffer, T Rivkind, M Schaffer. less Curr Oncol, 2018 Nov 23; 25(5). PMID: 30464697 Free PMC article. Review.
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Crosstalk Between PD-1/PD-L1 Blockade and Its Combinatorial Therapies in Tumor Immune Microenvironment: A Focus on HNSCC. Weimin Lin, Miao Chen, +2 authors, Le Hong, Hang Zhao, Qianming Chen. less Front Oncol, 2018 Dec 07; 8. PMID: 30519541 Free PMC article. Review.
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Combination PD-1 blockade and irradiation of brain metastasis induces an effective abscopal effect in melanoma. Lukas W Pfannenstiel, Corey McNeilly, +4 authors, Chaomei Xiang, Kai Kang, Claudia Marcella Diaz-Montero, Jennifer S Yu, Brian R Gastman. less Oncoimmunology, 2018 Dec 14; 8(1). PMID: 30546944 Free PMC article.
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Immune Modulation of Head and Neck Squamous Cell Carcinoma and the Tumor Microenvironment by Conventional Therapeutics. Sayuri Miyauchi, Sangwoo S Kim, +6 authors, John Pang, Kathryn A Gold, J Silvio Gutkind, Joseph A Califano, Loren K Mell, Ezra E W Cohen, Andrew B Sharabi. less Clin Cancer Res, 2019 Mar 01; 25(14). PMID: 30814108 Free PMC article. Review.
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Hyperprogressive disease after treatment with pembrolizumab in lung adenocarcinoma: An autopsy case study. Yuko Tanaka, Osamu Matsubara, +3 authors, Kazuhiro Asada, Aya Muramatsu, Makoto Suzuki, Toshihiro Shirai. less Respir Med Case Rep, 2019 Jun 30; 28. PMID: 31249779 Free PMC article.
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Future of Radiotherapy in Nasopharyngeal Carcinoma. Xue-Song Sun, Xiao-Yun Li, +2 authors, Qiu-Yan Chen, Lin-Quan Tang, Hai-Qiang Mai. less Br J Radiol, 2019 Jul 03; 92(1102). PMID: 31265322 Free PMC article.
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A Pilot Study of the PD-1 Targeting Agent AMP-224 Used With Low-Dose Cyclophosphamide and Stereotactic Body Radiation Therapy in Patients With Metastatic Colorectal Cancer. Charalampos S Floudas, Gagandeep Brar, +13 authors, Donna Mabry-Hrones, Austin G Duffy, Bradford Wood, Elliot Levy, Venkatesh Krishnasamy, Suzanne Fioravanti, Cecilia M Bonilla, Melissa Walker, Maria Pia Morelli, David E Kleiner, Seth M Steinberg, William D Figg, Tim F Greten, Changqing Xie. less Clin Colorectal Cancer, 2019 Jul 29; 18(4). PMID: 31351862 Free PMC article.
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Type I IFN protects cancer cells from CD8+ T cell-mediated cytotoxicity after radiation. Jianzhou Chen, Yunhong Cao, +3 authors, Bostjan Markelc, Jakob Kaeppler, Jenny Af Vermeer, Ruth J Muschel. less J Clin Invest, 2019 Sep 05; 129(10). PMID: 31483286 Free PMC article.
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Real-World Outcomes and Prognostic Factors in Patients Receiving Nivolumab Therapy for Recurrent or Metastatic Head and Neck Carcinoma. Ryusuke Hori, Shogo Shinohara, +12 authors, Tsuyoshi Kojima, Hiroki Kagoshima, Morimasa Kitamura, Ichiro Tateya, Hisanobu Tamaki, Yohei Kumabe, Ryo Asato, Hiroyuki Harada, Yoshiharu Kitani, Takashi Tsujimura, Keigo Honda, Kazuyuki Ichimaru, Koichi Omori. less Cancers (Basel), 2019 Sep 11; 11(9). PMID: 31500103 Free PMC article.
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Myeloid-Derived Suppressive Cells Promote B cell-Mediated Immunosuppression via Transfer of PD-L1 in Glioblastoma. Catalina Lee-Chang, Aida Rashidi, +13 authors, Jason Miska, Peng Zhang, Katarzyna C Pituch, David Hou, Ting Xiao, Mariafausta Fischietti, Seong Jae Kang, Christina L Appin, Craig Horbinski, Leonidas C Platanias, Aurora Lopez-Rosas, Yu Han, Irina V Balyasnikova, Maciej S Lesniak. less Cancer Immunol Res, 2019 Sep 19; 7(12). PMID: 31530559 Free PMC article.
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Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11. Xueting Lang, Michael D Green, +20 authors, Weimin Wang, Jiali Yu, Jae Eun Choi, Long Jiang, Peng Liao, Jiajia Zhou, Qiang Zhang, Ania Dow, Anjali L Saripalli, Ilona Kryczek, Shuang Wei, Wojciech Szeliga, Linda Vatan, Everett M Stone, George Georgiou, Marcin Cieslik, Daniel R Wahl, Meredith A Morgan, Arul M Chinnaiyan, Theodore S Lawrence, Weiping Zou. less Cancer Discov, 2019 Sep 27; 9(12). PMID: 31554642 Free PMC article. Highly Cited.
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β2 adrenergic receptor-mediated signaling regulates the immunosuppressive potential of myeloid-derived suppressor cells. Hemn Mohammadpour, Cameron R MacDonald, +6 authors, Guanxi Qiao, Minhui Chen, Bowen Dong, Bonnie L Hylander, Philip L McCarthy, Scott I Abrams, Elizabeth A Repasky. less J Clin Invest, 2019 Oct 01; 129(12). PMID: 31566578 Free PMC article.
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Combination of checkpoint inhibitors with radiotherapy in esophageal squamous cell carcinoma treatment: A novel strategy. Xiu-Yong Liao, Chao-Yuan Liu, +2 authors, Jian-Feng He, Li-Shu Wang, Tao Zhang. less Oncol Lett, 2019 Oct 16; 18(5). PMID: 31612012 Free PMC article. Review.
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Abscopal Effect Following Proton Beam Radiotherapy in a Patient With Inoperable Metastatic Retroperitoneal Sarcoma. Randall J Brenneman, Nima Sharifai, +6 authors, Benjamin Fischer-Valuck, Comron Hassanzadeh, Jeffrey Guzelian, John S A Chrisinger, Jeff M Michalski, Peter Oppelt, Brian C Baumann. less Front Oncol, 2019 Oct 17; 9. PMID: 31616634 Free PMC article.
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Randomized phase II trial reporting overall survival advantage by adding local consolidative therapy to systemic therapy for oligometastatic non-small cell lung cancer: another step forward on the long road of evidence-based medicine for oligometastatic disease. Paul Windisch, Matthias Guckenberger. J Thorac Dis, 2019 Oct 22; 11(Suppl 15). PMID: 31632771 Free PMC article.
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The Microenvironment of Pituitary Tumors-Biological and Therapeutic Implications. Mirela Diana Ilie, Alexandre Vasiljevic, Gérald Raverot, Philippe Bertolino. Cancers (Basel), 2019 Oct 24; 11(10). PMID: 31640258 Free PMC article. Review.
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The role of exosomal PD-L1 in tumor progression and immunotherapy. Feiting Xie, Mengxue Xu, +2 authors, Jian Lu, Lingxiang Mao, Shengjun Wang. less Mol Cancer, 2019 Oct 28; 18(1). PMID: 31647023 Free PMC article. Highly Cited. Review.
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What is the role of radiotherapy for extensive-stage small cell lung cancer in the immunotherapy era? Eric G Nesbit, Ticiana A Leal, Tim J Kruser. Transl Lung Cancer Res, 2019 Nov 02; 8(Suppl 2). PMID: 31673520 Free PMC article. Review.
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Durvalumab for stage III non-small-cell lung cancer patients: clinical evidence and real-world experience. Angela Botticella, Laura Mezquita, Cecile Le Pechoux, David Planchard. Ther Adv Respir Dis, 2019 Nov 07; 13. PMID: 31686616 Free PMC article.
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Recent advances and application of PD-1 blockade in sarcoma. Wenli Zuo, Lingdi Zhao. Onco Targets Ther, 2019 Nov 07; 12. PMID: 31692518 Free PMC article.
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IFN-γ down-regulates the PD-1 expression and assist nivolumab in PD-1-blockade effect on CD8+ T-lymphocytes in pancreatic cancer. Guoping Ding, Tao Shen, +3 authors, Chen Yan, Mingjie Zhang, Zhengrong Wu, Liping Cao. less BMC Cancer, 2019 Nov 07; 19(1). PMID: 31694582 Free PMC article.
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A preliminary Study on the Effect of Head and Neck Chemoradiotherapy on Systematic Immunity. Weiqiang Huang, Yao Fan, +5 authors, Xiaoya Cheng, Huazhen Liang, Hua Pan, Ting Xiao, Min Chen, Jian Guan. less Dose Response, 2019 Nov 07; 17(4). PMID: 31695581 Free PMC article.
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Immune Checkpoint Inhibition in Hodgkin Lymphoma. Ryan H Moy, Anas Younes. Hemasphere, 2018 Feb 16; 2(1). PMID: 31723749 Free PMC article. Review.
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The Future of Combining Carbon-Ion Radiotherapy with Immunotherapy: Evidence and Progress in Mouse Models. Takashi Shimokawa, Liqiu Ma, +2 authors, Ken Ando, Katsutoshi Sato, Takashi Imai. less Int J Part Ther, 2016 Jul 01; 3(1). PMID: 31772976 Free PMC article. Review.
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Advantages and Limitations in the Use of Combination Therapies with Charged Particle Radiation Therapy. Koji Tsuboi. Int J Part Ther, 2018 Jul 01; 5(1). PMID: 31773024 Free PMC article. Review.
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Is the Combination of Immunotherapy and Radiotherapy in Non-small Cell Lung Cancer a Feasible and Effective Approach? Mathieu Spaas, Yolande Lievens. Front Med (Lausanne), 2019 Dec 04; 6. PMID: 31788476 Free PMC article. Review.
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Evolving management of positive regional lymph nodes in melanoma: Past, present and future directions. Rachel A Fayne, Francisco I Macedo, Steven E Rodgers, Mecker G Möller. Oncol Rev, 2019 Dec 21; 13(2). PMID: 31857858 Free PMC article.
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Sequential Ipilimumab After Chemoradiotherapy in Curative-Intent Treatment of Patients With Node-Positive Cervical Cancer. Jyoti S Mayadev, Danielle Enserro, +8 authors, Yvonne G Lin, Diane M Da Silva, Heather A Lankes, Carol Aghajanian, Sharad Ghamande, Kathleen N Moore, Vanessa A Kennedy, Paula M Fracasso, Russell J Schilder. less JAMA Oncol, 2019 Nov 28; 6(1). PMID: 31774464 Free PMC article.
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Therapy Resistance in Neoadjuvantly Treated Gastric Cancer and Cancer of the Gastroesophageal Junction is Associated with an Increased Expression of Immune Checkpoint Inhibitors-Comparison Against a Therapy Naïve Cohort. Hauke Schoop, Anna Bregenzer, +4 authors, Christine Halske, Hans-Michael Behrens, Sandra Krüger, Jan-Hendrik Egberts, Christoph Röcken. less Transl Oncol, 2019 Dec 23; 13(2). PMID: 31865179 Free PMC article.
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Microparticles from tumors exposed to radiation promote immune evasion in part by PD-L1. Michael Timaner, Ruslana Kotsofruk, +10 authors, Ziv Raviv, Ksenia Magidey, Dvir Shechter, Tal Kan, Alexander Nevelsky, Shahar Daniel, Elisabeth G E de Vries, Tongwu Zhang, Orit Kaidar-Person, Robert S Kerbel, Yuval Shaked. less Oncogene, 2019 Aug 31; 39(1). PMID: 31467431 Free PMC article.
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Indoleamine 2,3-dioxygenase 1 and Programmed Cell Death-ligand 1 Co-expression Predicts Poor Pathologic Response and Recurrence in Esophageal Squamous Cell Carcinoma after Neoadjuvant Chemoradiotherapy. Sha Zhou, Lei Zhao, +6 authors, Zhaohui Liang, Songran Liu, Yong Li, Shiliang Liu, Hong Yang, Mengzhong Liu, Mian Xi. less Cancers (Basel), 2019 Feb 06; 11(2). PMID: 30717285 Free PMC article.
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Separating or combining immune checkpoint inhibitors (ICIs) and radiotherapy in the treatment of NSCLC brain metastases. Wang Li, Hong Yu. J Cancer Res Clin Oncol, 2019 Dec 10; 146(1). PMID: 31813004 Review.
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Efficacy of anti-PD-1 therapy for recurrence after chemoradiotherapy in locally advanced NSC LC. Yoshiaki Amino, Satoru Kitazono, +8 authors, Shinya Uematsu, Tsukasa Hasegawa, Takahiro Yoshizawa, Ken Uchibori, Noriko Yanagitani, Atsushi Horiike, Takeshi Horai, Kazuo Kasahara, Makoto Nishio. less Int J Clin Oncol, 2019 Sep 12; 25(1). PMID: 31506751
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Targeting innate sensing in the tumor microenvironment to improve immunotherapy. Zhida Liu, Chuanhui Han, Yang-Xin Fu. Cell Mol Immunol, 2019 Dec 18; 17(1). PMID: 31844141 Free PMC article. Review.
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Amplifying Outcomes: Checkpoint Inhibitor Combinations in First-Line Non-Small Cell Lung Cancer. Barbara Melosky, Rosalyn Juergens, +5 authors, Vera Hirsh, Deanna McLeod, Natasha Leighl, Ming-Sound Tsao, Paul B Card, Quincy Chu. less Oncologist, 2019 May 30; 25(1). PMID: 31138727 Free PMC article.
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A Novel Anti-PD-L1 Vaccine for Cancer Immunotherapy and Immunoprevention. Jie Chen, Hui Liu, +7 authors, Tiffany Jehng, Yanqing Li, Zhoushi Chen, Kuan-Der Lee, Hsieh-Tsung Shen, Lindsey Jones, Xue F Huang, Si-Yi Chen. less Cancers (Basel), 2019 Dec 07; 11(12). PMID: 31805690 Free PMC article.
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Radiation-induced alterations in immunogenicity of a murine pancreatic ductal adenocarcinoma cell line. Philipp Schröter, Laura Hartmann, +6 authors, Wolfram Osen, Daniel Baumann, Rienk Offringa, David Eisel, Jürgen Debus, Stefan B Eichmüller, Stefan Rieken. less Sci Rep, 2020 Jan 22; 10(1). PMID: 31959787 Free PMC article.
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Impact of histology on patterns of failure and clinical outcomes in patients treated with definitive chemoradiotherapy for locally advanced non-small cell lung cancer. Hitoshi Ito, Yukinori Matsuo, +4 authors, Shuji Ohtsu, Takashi Nishimura, Yasuji Terada, Takashi Sakamoto, Takashi Mizowaki. less Int J Clin Oncol, 2019 Nov 02; 25(2). PMID: 31667664
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The PEMBRO-RT phase II randomized trial and the evolution of therapy for metastatic non-small cell lung cancer: a historical perspective. Steven E Schild. Ann Transl Med, 2020 Feb 06; 7(Suppl 8). PMID: 32016013 Free PMC article.
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A first attempt to establish a definition of oligometastatic non-small cell lung cancer by a European consensus group. Koji Haratani, Masayuki Takeda, Kazuhiko Nakagawa. J Thorac Dis, 2020 Feb 08; 11(12). PMID: 32030287 Free PMC article.
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Local consolidative therapy for oligometastatic patients with stage IV non-small cell lung cancer may improve survival, but unanswered questions remain. Jose M Pacheco, Drew Moghanaki. Transl Lung Cancer Res, 2020 Feb 11; 8(Suppl 4). PMID: 32038926 Free PMC article.
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Immune biological rationales for the design of combined radio- and immunotherapies. Michael Hader, Benjamin Frey, +2 authors, Rainer Fietkau, Markus Hecht, Udo S Gaipl. less Cancer Immunol Immunother, 2020 Jan 19; 69(2). PMID: 31953578 Free PMC article. Review.
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Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma. Sharareh Gholamin, Osama A Youssef, +8 authors, Marjan Rafat, Rogelio Esparza, Suzana Kahn, Maryam Shahin, Amato J Giaccia, Edward E Graves, Irving Weissman, Siddhartha Mitra, Samuel H Cheshier. less Innate Immun, 2019 Sep 25; 26(2). PMID: 31547758 Free PMC article.
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The changing role of radiation therapy in the management of oligometastatic disease. H Tharmalingham, P J Hoskin. Tech Innov Patient Support Radiat Oncol, 2017 Feb 16; 1. PMID: 32095538 Free PMC article.
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Immune Checkpoint Inhibitors for the Treatment of Unresectable Stage III Non-Small Cell Lung Cancer: Emerging Mechanisms and Perspectives. Hiroyuki Inoue, Isamu Okamoto. Lung Cancer (Auckl), 2020 Feb 27; 10. PMID: 32099495 Free PMC article. Review.
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Radiotherapy as a Backbone for Novel Concepts in Cancer Immunotherapy. Julijan Kabiljo, Felix Harpain, Sebastian Carotta, Michael Bergmann. Cancers (Basel), 2020 Jan 08; 12(1). PMID: 31905723 Free PMC article. Review.
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Hypofractionated Irradiation Suppressed the Off-Target Mouse Hepatocarcinoma Growth by Inhibiting Myeloid-Derived Suppressor Cell-Mediated Immune Suppression. Junying Chen, Zeng Wang, +11 authors, Yuxiong Ding, Fei Huang, Weikang Huang, Ruilong Lan, Ruiqing Chen, Bing Wu, Lengxi Fu, Yunhua Yang, Jun Liu, Jinsheng Hong, Weijian Zhang, Lurong Zhang. less Front Oncol, 2020 Mar 03; 10. PMID: 32117702 Free PMC article.
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PD-L1 Expression in Circulating Tumor Cells Increases during Radio(chemo)therapy and Indicates Poor Prognosis in Non-small Cell Lung Cancer. Yang Wang, Tae Hyun Kim, +9 authors, Shamileh Fouladdel, Zhuo Zhang, Payal Soni, Angel Qin, Lili Zhao, Ebrahim Azizi, Theodore S Lawrence, Nithya Ramnath, Kyle C Cuneo, Sunitha Nagrath. less Sci Rep, 2019 Jan 27; 9(1). PMID: 30679441 Free PMC article. Highly Cited.
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STING, DCs and the link between innate and adaptive tumor immunity. Ralph E Vatner, Edith M Janssen. Mol Immunol, 2017 Dec 24; 110. PMID: 29273394 Free PMC article. Review.
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Treatment of Canine Oral Melanoma with Nanotechnology-Based Immunotherapy and Radiation. P Jack Hoopes, Robert J Wagner, +8 authors, Kayla Duval, Kevin Kang, David J Gladstone, Karen L Moodie, Margaret Crary-Burney, Hugo Ariaspulido, Frank A Veliz, Nicole F Steinmetz, Steven N Fiering. less Mol Pharm, 2018 Apr 04; 15(9). PMID: 29613803 Free PMC article.
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Immunological Mechanisms Responsible for Radiation-Induced Abscopal Effect. María E Rodríguez-Ruiz, Claire Vanpouille-Box, +2 authors, Ignacio Melero, Silvia Chiara Formenti, Sandra Demaria. less Trends Immunol, 2018 Jul 14; 39(8). PMID: 30001871 Free PMC article. Highly Cited. Review.
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IFNγ PET Imaging as a Predictive Tool for Monitoring Response to Tumor Immunotherapy. Heather M Gibson, Brooke N McKnight, +6 authors, Agnes Malysa, Greg Dyson, Wendy N Wiesend, Claire E McCarthy, Joyce Reyes, Wei-Zen Wei, Nerissa T Viola-Villegas. less Cancer Res, 2018 Aug 18; 78(19). PMID: 30115693 Free PMC article.
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Anti-drug antibodies to LMB-100 are enhanced by mAbs targeting OX40 and CTLA4 but not by mAbs targeting PD1 or PDL-1. Ronit Mazor, Emily King, Ira Pastan. Cell Immunol, 2018 Sep 15; 334. PMID: 30213644 Free PMC article.
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Tumor regression after combination of radiation and PD-1 antibody nivolumab treatment in a patient with metastatic mediastinal leiomyosarcoma: a case report. Chen Xi, Zhang Wencheng, +7 authors, Qian Dong, Guan Yong, Yan Cihui, Wang Yuwen, Zhang Hualei, Er Puchun, Pang Qingsong, Wang Ping. less Cancer Biol Ther, 2018 Nov 06; 20(4). PMID: 30388926 Free PMC article.
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Immunotherapies based on PD-1/PD-L1 pathway inhibitors in ovarian cancer treatment. A Pawłowska, D Suszczyk, +3 authors, K Okła, B Barczyński, J Kotarski, I Wertel. less Clin Exp Immunol, 2018 Dec 26; 195(3). PMID: 30582756 Free PMC article. Review.
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Immunomodulation of the Tumor Microenvironment: Turn Foe Into Friend. Hanne Locy, Sven de Mey, +3 authors, Wout de Mey, Mark De Ridder, Kris Thielemans, Sarah K Maenhout. less Front Immunol, 2019 Jan 09; 9. PMID: 30619273 Free PMC article. Highly Cited. Review.
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Potential Role of CXCR4 Targeting in the Context of Radiotherapy and Immunotherapy of Cancer. Franziska Eckert, Karin Schilbach, +5 authors, Lukas Klumpp, Lilia Bardoscia, Efe Cumhur Sezgin, Matthias Schwab, Daniel Zips, Stephan M Huber. less Front Immunol, 2019 Jan 10; 9. PMID: 30622535 Free PMC article. Review.
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A Blazing Landscape: Neuroinflammation Shapes Brain Metastasis. Hila Doron, Tobias Pukrop, Neta Erez. Cancer Res, 2019 Jan 27; 79(3). PMID: 30679177 Free PMC article. Review.
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Combining Radiotherapy With Anti-angiogenic Therapy and Immunotherapy; A Therapeutic Triad for Cancer? Ruben S A Goedegebuure, Leonie K de Klerk, +2 authors, Adam J Bass, Sarah Derks, Victor L J L Thijssen. less Front Immunol, 2019 Jan 30; 9. PMID: 30692993 Free PMC article. Review.
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Overcoming Resistance to Combination Radiation-Immunotherapy: A Focus on Contributing Pathways Within the Tumor Microenvironment. Laurel B Darragh, Ayman J Oweida, Sana D Karam. Front Immunol, 2019 Feb 16; 9. PMID: 30766539 Free PMC article. Review.
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The Role of Radiation Oncology in Immuno-Oncology. Xiangjiao Meng, Rui Feng, +2 authors, Lian Yang, Ligang Xing, Jinming Yu. less Oncologist, 2019 Mar 02; 24(Suppl 1). PMID: 30819830 Free PMC article. Review.
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90Y-NM600 targeted radionuclide therapy induces immunologic memory in syngeneic models of T-cell Non-Hodgkin's Lymphoma. Reinier Hernandez, Kirsti L Walker, +12 authors, Joseph J Grudzinski, Eduardo Aluicio-Sarduy, Ravi Patel, Christopher D Zahm, Anatoly N Pinchuk, Christopher F Massey, Ariana N Bitton, Ryan J Brown, Paul M Sondel, Zachary S Morris, Jonathan W Engle, Christian M Capitini, Jamey P Weichert. less Commun Biol, 2019 Mar 02; 2. PMID: 30820474 Free PMC article.
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Direct and antibody-dependent cell-mediated cytotoxicity of head and neck squamous cell carcinoma cells by high-affinity natural killer cells. Jay Friedman, Michelle Padget, +3 authors, John Lee, Jeffrey Schlom, James Hodge, Clint Allen. less Oral Oncol, 2019 Mar 09; 90. PMID: 30846174 Free PMC article.
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Immune targets in the tumor microenvironment treated by radiotherapy. Omer M Ozpiskin, Lu Zhang, Jian Jian Li. Theranostics, 2019 Mar 15; 9(5). PMID: 30867826 Free PMC article. Highly Cited. Review.
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Radiotherapy is an independent prognostic marker of favorable prognosis in non-small cell lung cancer patients after treatment with the immune checkpoint inhibitor, nivolumab. Ou Yamaguchi, Kyoichi Kaira, +9 authors, Kosuke Hashimoto, Atsuto Mouri, Yu Miura, Ayako Shiono, Fuyumi Nishihara, Yoshitake Murayama, Shin-Ei Noda, Shingo Kato, Kunihiko Kobayashi, Hiroshi Kagamu. less Thorac Cancer, 2019 Mar 20; 10(4). PMID: 30888716 Free PMC article.
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Pancreatic Tumor Microenvironment Modulation by EphB4-ephrinB2 Inhibition and Radiation Combination. Shelby Lennon, Ayman Oweida, +17 authors, Dallin Milner, Andy V Phan, Shilpa Bhatia, Benjamin Van Court, Laurel Darragh, Adam C Mueller, David Raben, Jorge L Martínez-Torrecuadrada, Todd M Pitts, Hilary Somerset, Kimberly R Jordan, Kirk C Hansen, Jason Williams, Wells A Messersmith, Richard D Schulick, Philip Owens, Karyn A Goodman, Sana D Karam. less Clin Cancer Res, 2019 Apr 05; 25(11). PMID: 30944125 Free PMC article.
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[Durvalumab after chemoradiotherapy is currently the most promising treatment for stage III NSCLC]. Martin Wilhelm. Strahlenther Onkol, 2019 Apr 06; 195(7). PMID: 30949719
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Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory. Mauro Poggio, Tianyi Hu, +8 authors, Chien-Chun Pai, Brandon Chu, Cassandra D Belair, Anthony Chang, Elizabeth Montabana, Ursula E Lang, Qi Fu, Lawrence Fong, Robert Blelloch. less Cell, 2019 Apr 06; 177(2). PMID: 30951669 Free PMC article. Highly Cited.
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Noninvasive Imaging and Quantification of Radiotherapy-Induced PD-L1 Upregulation with 89Zr-Df-Atezolizumab. Emily B Ehlerding, Hye Jin Lee, +5 authors, Todd E Barnhart, Dawei Jiang, Lei Kang, Douglas G McNeel, Jonathan W Engle, Weibo Cai. less Bioconjug Chem, 2019 Apr 12; 30(5). PMID: 30973703 Free PMC article.
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Feline XLF accumulates at DNA damage sites in a Ku-dependent manner. Manabu Koike, Yasutomo Yutoku, Aki Koike. FEBS Open Bio, 2019 May 23; 9(6). PMID: 31115163 Free PMC article.
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PD-L1 detection using 89Zr-atezolizumab immuno-PET in renal cell carcinoma tumorgrafts from a patient with favorable nivolumab response. Joseph Vento, Aditi Mulgaonkar, +11 authors, Layton Woolford, Kien Nham, Alana Christie, Aditya Bagrodia, Alberto Diaz de Leon, Raquibul Hannan, Isaac Bowman, Renee M McKay, Payal Kapur, Guiyang Hao, Xiankai Sun, James Brugarolas. less J Immunother Cancer, 2019 Jun 04; 7(1). PMID: 31155004 Free PMC article.
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Abscopal Effects in Radio-Immunotherapy-Response Analysis of Metastatic Cancer Patients With Progressive Disease Under Anti-PD-1 Immune Checkpoint Inhibition. Maike Trommer, Sin Yuin Yeo, +10 authors, Thorsten Persigehl, Anne Bunck, Holger Grüll, Max Schlaak, Sebastian Theurich, Michael von Bergwelt-Baildon, Janis Morgenthaler, Jan M Herter, Eren Celik, Simone Marnitz, Christian Baues. less Front Pharmacol, 2019 Jun 04; 10. PMID: 31156434 Free PMC article.
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Pre-clinical blocking of PD-L1 molecule, which expression is down regulated by NF-κB, JAK1/JAK2 and BTK inhibitors, induces regression of activated B-cell lymphoma. Christelle Vincent-Fabert, Lilian Roland, +2 authors, Ursula Zimber-Strobl, Jean Feuillard, Nathalie Faumont. less Cell Commun Signal, 2019 Aug 07; 17(1). PMID: 31382969 Free PMC article.
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MicroRNA-200a induces immunosuppression by promoting PTEN-mediated PD-L1 upregulation in osteosarcoma. Zhuochao Liu, Junxiang Wen, +9 authors, Chuanlong Wu, Chuanzhen Hu, Jun Wang, Qiyuan Bao, Hongyi Wang, Jizhuang Wang, Qi Zhou, Li Wei, Yuhui Shen, Weibin Zhang. less Aging (Albany NY), 2020 Jan 26; 12(2). PMID: 31981455 Free PMC article.
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Phase 1 Trial of Pembrolizumab Administered Concurrently With Chemoradiotherapy for Locally Advanced Non-Small Cell Lung Cancer: A Nonrandomized Controlled Trial. Salma K Jabbour, Abigail T Berman, +9 authors, Roy H Decker, Yong Lin, Steven J Feigenberg, Scott N Gettinger, Charu Aggarwal, Corey J Langer, Charles B Simone, Jeffrey D Bradley, Joseph Aisner, Jyoti Malhotra. less JAMA Oncol, 2020 Feb 23; 6(6). PMID: 32077891 Free PMC article.
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The Reduced Oligomerization of MAVS Mediated by ROS Enhances the Cellular Radioresistance. Yarong Du, Dong Pan, +4 authors, Rong Jia, Yaxiong Chen, Cong Jia, Jufang Wang, Burong Hu. less Oxid Med Cell Longev, 2020 Mar 20; 2020. PMID: 32190169 Free PMC article.
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Advances and challenges in immunotherapy of small cell lung cancer. Hanfei Guo, Lingyu Li, Jiuwei Cui. Chin J Cancer Res, 2020 Mar 21; 32(1). PMID: 32194311 Free PMC article.
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T cell recruitment triggered by optimal dose platinum compounds contributes to the therapeutic efficacy of sequential PD-1 blockade in a mouse model of colon cancer. Deqiang Fu, Jichun Wu, +4 authors, Jinzhi Lai, Ying Liu, Linlin Zhou, Ling Chen, Qiuyu Zhang. less Am J Cancer Res, 2020 Mar 21; 10(2). PMID: 32195021 Free PMC article.
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Determinants of Resistance to Checkpoint Inhibitors. Linda Tran, Dan Theodorescu. Int J Mol Sci, 2020 Mar 01; 21(5). PMID: 32111080 Free PMC article. Review.
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Putative Abscopal Effect in Three Patients Treated by Combined Radiotherapy and Modulated Electrohyperthermia. Mau-Shin Chi, Minesh P Mehta, +6 authors, Kai-Lin Yang, Hung-Chih Lai, Ying-Chu Lin, Hui-Ling Ko, Yu-Shan Wang, Kuang-Wen Liao, Kwan-Hwa Chi. less Front Oncol, 2020 Mar 27; 10. PMID: 32211319 Free PMC article.
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Quantitative PET imaging of PD-L1 expression in xenograft and syngeneic tumour models using a site-specifically labelled PD-L1 antibody. Camilla Christensen, Lotte K Kristensen, +2 authors, Maria Z Alfsen, Carsten H Nielsen, Andreas Kjaer. less Eur J Nucl Med Mol Imaging, 2019 Dec 29; 47(5). PMID: 31883023 Free PMC article.
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Downregulation of Nitric Oxide Collaborated with Radiotherapy to Promote Anti-Tumor Immune Response via Inducing CD8+ T Cell Infiltration. Jieyu Xu, Yuan Luo, +11 authors, Cheng Yuan, Linzhi Han, Qiuji Wu, Liexi Xu, Yuke Gao, Yingming Sun, Shijing Ma, Guiliang Tang, Shuying Li, Wenjie Sun, Yan Gong, Conghua Xie. less Int J Biol Sci, 2020 Apr 01; 16(9). PMID: 32226302 Free PMC article.
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Current status and progress of concurrent chemoradiotherapy in patients with locally advanced non-small cell lung cancer prior to the approval of durvalumab. Tomoya Fukui, Shinji Hosotani, +13 authors, Itaru Soda, Takahiro Ozawa, Seiichiro Kusuhara, Mikiko I Kakegawa, Masashi Kasajima, Yasuhiro Hiyoshi, Satoshi Igawa, Masanori Yokoba, Hisashi Mitsufuji, Masaru Kubota, Masato Katagiri, Jiichiro Sasaki, Hiromichi Ishiyama, Katsuhiko Naoki. less Thorac Cancer, 2020 Feb 15; 11(4). PMID: 32057187 Free PMC article.
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HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING. Xiaobo Luo, Christopher R Donnelly, +21 authors, Wang Gong, Blake R Heath, Yuning Hao, Lorenza A Donnelly, Toktam Moghbeli, Yee Sun Tan, Xin Lin, Emily Bellile, Benjamin A Kansy, Thomas E Carey, J Chad Brenner, Lei Cheng, Peter J Polverini, Meredith A Morgan, Haitao Wen, Mark E Prince, Robert L Ferris, Yuying Xie, Simon Young, Gregory T Wolf, Qianming Chen, Yu L Lei. less J Clin Invest, 2019 Dec 25; 130(4). PMID: 31874109 Free PMC article.
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Interferon-Induced IDO1 Mediates Radiation Resistance and Is a Therapeutic Target in Colorectal Cancer. Baosheng Chen, David M Alvarado, +5 authors, Micah Iticovici, Nathan S Kau, Haeseong Park, Parag J Parikh, Dinesh Thotala, Matthew A Ciorba. less Cancer Immunol Res, 2020 Mar 05; 8(4). PMID: 32127391 Free PMC article.
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The emerging role of myeloid-derived suppressor cells in radiotherapy. Changhee Kang, Seong-Yun Jeong, Si Yeol Song, Eun Kyung Choi. Radiat Oncol J, 2020 Apr 02; 38(1). PMID: 32229803 Free PMC article.
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Practical challenges in patients with stage III NSCLC receiving checkpoint inhibitors after chemoradiation. Nikhil A Shukla, Nasser H Hanna. Lung Cancer Manag, 2020 Apr 08; 9(1). PMID: 32256709 Free PMC article.
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Immunotherapy and radiation therapy for gastrointestinal malignancies: hope or hype? Shahed Badiyan, Adeel Kaiser, +4 authors, Bory Eastman, Matthew Forsthoefel, Jing Zeng, Keith Unger, Michael Chuong. less Transl Gastroenterol Hepatol, 2020 Apr 08; 5. PMID: 32258525 Free PMC article. Review.
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Low-Dose Total Body Irradiation Can Enhance Systemic Immune Related Response Induced by Hypo-Fractionated Radiation. Jing Liu, Jie Zhou, +10 authors, Min Wu, ChuanFei Hu, Juan Yang, Dong Li, Peng Wu, Yue Chen, Ping Chen, Sheng Lin, YongXia Cui, ShaoZhi Fu, JingBo Wu. less Front Immunol, 2019 Mar 16; 10. PMID: 30873170 Free PMC article.
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Rationale for Combining Radiotherapy and Immune Checkpoint Inhibition for Patients With Hypoxic Tumors. Franziska Eckert, Kerstin Zwirner, +3 authors, Simon Boeke, Daniela Thorwarth, Daniel Zips, Stephan M Huber. less Front Immunol, 2019 Apr 02; 10. PMID: 30930892 Free PMC article. Review.
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The Multifactorial Role of PARP-1 in Tumor Microenvironment. Juan Manuel Martí, Mónica Fernández-Cortés, +4 authors, Santiago Serrano-Sáenz, Esteban Zamudio-Martinez, Daniel Delgado-Bellido, Angel Garcia-Diaz, Francisco Javier Oliver. less Cancers (Basel), 2020 Apr 05; 12(3). PMID: 32245040 Free PMC article. Review.
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Development and validation of an immune-related gene pairs signature in colorectal cancer. Jianping Wu, Ying Zhao, +2 authors, Juanwen Zhang, Qianxia Wu, Weilin Wang. less Oncoimmunology, 2019 May 31; 8(7). PMID: 31143520 Free PMC article.
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Synergistic effects of anti-PDL-1 with ablative radiation comparing to other regimens with same biological effect dose based on different immunogenic response. Maedeh Alinezhad, Mohsen Bakhshandeh, +3 authors, Elham Rostami, Reza Alimohamadi, Nariman Mosaffa, Seyed Amir Jalali. less PLoS One, 2020 Apr 15; 15(4). PMID: 32287292 Free PMC article.
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Breast cancer immunology and immunotherapy: targeting the programmed cell death protein-1/programmed cell death protein ligand-1. Jing Zhao, Jian Huang. Chin Med J (Engl), 2020 Feb 28; 133(7). PMID: 32106121 Free PMC article. Review.
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Mathematical modeling of tumor-immune cell interactions. Grace E Mahlbacher, Kara C Reihmer, Hermann B Frieboes. J Theor Biol, 2019 Mar 06; 469. PMID: 30836073 Free PMC article. Review.
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National Cancer Institute (NCI) state of the science: Targeted radiosensitizers in colorectal cancer. Thomas J George, Aaron J Franke, +16 authors, A Bapsi Chakravarthy, Prajnan Das, Arvind Dasari, Bassel F El-Rayes, Theodore S Hong, Timothy J Kinsella, Jerome C Landry, James J Lee, Arta M Monjazeb, Samuel A Jacobs, David Raben, Osama E Rahma, Terence M Williams, Christina Wu, C Norman Coleman, Bhadrasain Vikram, Mansoor M Ahmed. less Cancer, 2019 Apr 25; 125(16). PMID: 31017664 Free PMC article. Review.
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Recent Findings in the Regulation of Programmed Death Ligand 1 Expression. Xiangfeng Shen, Lihong Zhang, +3 authors, Jicheng Li, Yulin Li, Yishu Wang, Zhi-Xiang Xu. less Front Immunol, 2019 Jul 02; 10. PMID: 31258527 Free PMC article. Review.
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STING modulators: Predictive significance in drug discovery. Xiangling Cui, Rongyu Zhang, Shan Cen, Jinming Zhou. Eur J Med Chem, 2019 Aug 17; 182. PMID: 31419779 Free PMC article. Review.
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Ionizing radiation modulates the phenotype and function of human CD4+ induced regulatory T cells. Samantha S Beauford, Anita Kumari, Charlie Garnett-Benson. BMC Immunol, 2020 Apr 18; 21(1). PMID: 32299365 Free PMC article.
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Combination Strategies of Checkpoint Immunotherapy in Metastatic Breast Cancer. Zhi Bing Liu, Luyan Zhang, Jia Bian, Jinbo Jian. Onco Targets Ther, 2020 Apr 21; 13. PMID: 32308409 Free PMC article. Review.
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Modeling and Analyzing Stem-Cell Therapy toward Cancer: Evolutionary Game Theory Perspective. Zahra Veisi, Heydar Khadem, Samin Ravanshadi. Iran J Public Health, 2020 Apr 21; 49(1). PMID: 32309233 Free PMC article.
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Liver metastases and the efficacy of the PD-1 or PD-L1 inhibitors in cancer: a meta-analysis of randomized controlled trials. Shan Li, Shanquan Sun, +3 authors, Hui Xiang, Jing Yang, Minyong Peng, Qing Gao. less Oncoimmunology, 2020 Apr 22; 9(1). PMID: 32313724 Free PMC article.
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TENERGY: multicenter phase II study of Atezolizumab monotherapy following definitive Chemoradiotherapy with 5-FU plus Cisplatin in patients with unresectable locally advanced esophageal squamous cell carcinoma. Hideaki Bando, Daisuke Kotani, +15 authors, Takahiro Tsushima, Hiroki Hara, Shigenori Kadowaki, Ken Kato, Keisho Chin, Kensei Yamaguchi, Shun-Ichiro Kageyama, Hidehiro Hojo, Masaki Nakamura, Hidenobu Tachibana, Masashi Wakabayashi, Miki Fukutani, Yosuke Togashi, Nozomu Fuse, Hiroyoshi Nishikawa, Takashi Kojima. less BMC Cancer, 2020 Apr 22; 20(1). PMID: 32312286 Free PMC article.
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Apatinib Combined with Local Irradiation Leads to Systemic Tumor Control via Reversal of Immunosuppressive Tumor Microenvironment in Lung Cancer. Li-Jun Liang, Chen-Xi Hu, +12 authors, Yi-Xuan Wen, Xiao-Wei Geng, Ting Chen, Guo-Qing Gu, Lei Wang, You-You Xia, Yong Liu, Jia-Yan Fei, Jie Dong, Feng-Hua Zhao, Yiliyar Ahongjiang, Kai-Yuan Hui, Xiao-Dong Jiang. less Cancer Res Treat, 2019 Sep 04; 52(2). PMID: 31476848 Free PMC article.
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Optimized fractionated radiotherapy with anti-PD-L1 and anti-TIGIT: a promising new combination. Mathieu Grapin, Corentin Richard, +10 authors, Emeric Limagne, Romain Boidot, Véronique Morgand, Aurélie Bertaut, Valentin Derangere, Pierre-Antoine Laurent, Marion Thibaudin, Jean David Fumet, Gilles Crehange, François Ghiringhelli, Céline Mirjolet. less J Immunother Cancer, 2019 Jun 27; 7(1). PMID: 31238970 Free PMC article.
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Immunotherapy in small-cell lung cancer: from molecular promises to clinical challenges. A Pavan, I Attili, +3 authors, G Pasello, V Guarneri, P F Conte, L Bonanno. less J Immunother Cancer, 2019 Aug 07; 7(1). PMID: 31383005 Free PMC article. Review.
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Rationale of combination of anti-PD-1/PD-L1 antibody therapy and radiotherapy for cancer treatment. Hiro Sato, Noriyuki Okonogi, Takashi Nakano. Int J Clin Oncol, 2020 Apr 05; 25(5). PMID: 32246277 Free PMC article. Review.
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Transcriptional Upregulation of NLRC5 by Radiation Drives STING- and Interferon-Independent MHC-I Expression on Cancer Cells and T Cell Cytotoxicity. Lauren K Zebertavage, Alejandro Alice, Marka R Crittenden, Michael J Gough. Sci Rep, 2020 May 02; 10(1). PMID: 32355214 Free PMC article.
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Alteration in tumoural PD-L1 expression and stromal CD8-positive tumour-infiltrating lymphocytes after concurrent chemo-radiotherapy for non-small cell lung cancer. Kazue Yoneda, Taiji Kuwata, +7 authors, Masatoshi Kanayama, Masataka Mori, Toshinori Kawanami, Kazuhiro Yatera, Takayuki Ohguri, Masanori Hisaoka, Toshiyuki Nakayama, Fumihiro Tanaka. less Br J Cancer, 2019 Aug 08; 121(6). PMID: 31388183 Free PMC article.
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Using Preclinical Data to Design Combination Clinical Trials of Radiation Therapy and Immunotherapy. Michael J Gough, Shay Sharon, Marka R Crittenden, Kristina H Young. Semin Radiat Oncol, 2020 May 10; 30(2). PMID: 32381295 Free PMC article. Review.
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Novel Radiation Therapy Paradigms and Immunomodulation: Heresies and Hope. Suparna Dutt, Mansoor M Ahmed, Billy W Loo, Samuel Strober. Semin Radiat Oncol, 2020 May 10; 30(2). PMID: 32381299 Free PMC article. Review.
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A Pilot Feasibility Study of Yttrium-90 Liver Radioembolization Followed by Durvalumab and Tremelimumab in Patients with Microsatellite Stable Colorectal Cancer Liver Metastases. Chongkai Wang, John Park, +12 authors, Ching Ouyang, Jeff A Longmate, Michael Tajon, Joseph Chao, Dean Lim, Jaideep Sandhu, Hongwei Holly Yin, Raju Pillai, Maricel C Gozo, Christian Avalos, Colt A Egelston, Peter P Lee, Marwan Fakih. less Oncologist, 2019 Dec 21; 25(5). PMID: 31857446 Free PMC article.
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Head and Neck Cancer Immunotherapy beyond the Checkpoint Blockade. B R Heath, N L Michmerhuizen, +4 authors, C R Donnelly, K Sansanaphongpricha, D Sun, J C Brenner, Y L Lei. less J Dent Res, 2019 Jul 26; 98(10). PMID: 31340724 Free PMC article. Review.
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Current Approaches for Combination Therapy of Cancer: The Role of Immunogenic Cell Death. Zahra Asadzadeh, Elham Safarzadeh, +7 authors, Sahar Safaei, Ali Baradaran, Ali Mohammadi, Khalil Hajiasgharzadeh, Afshin Derakhshani, Antonella Argentiero, Nicola Silvestris, Behzad Baradaran. less Cancers (Basel), 2020 Apr 29; 12(4). PMID: 32340275 Free PMC article. Review.
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RADIANCE - Radiochemotherapy with or without Durvalumab in the treatment of anal squamous cell carcinoma: A randomized multicenter phase II trial. Daniel Martin, Panagiotis Balermpas, +20 authors, Johannes Gollrad, Christian Weiß, Chiara Valentini, Martin Stuschke, Henning Schäfer, Christoph Henckenberens, Jürgen Debus, David Krug, Thomas Kuhnt, Thomas Brunner, Tilman Bostel, Rita Engenhart-Cabillic, Ursula Nestle, Stephanie Combs, Claus Belka, Matthias Hautmann, Guido Hildebrandt, Cihan Gani, Bülent Polat, Claus Rödel, Emmanouil Fokas. less Clin Transl Radiat Oncol, 2020 May 19; 23. PMID: 32420463 Free PMC article.
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The abscopal effect 67 years later: from a side story to center stage. Sandra Demaria, Silvia C Formenti. Br J Radiol, 2020 Feb 27; 93(1109). PMID: 32101479 Free PMC article. Review.
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Soluble CD80 Protein Delays Tumor Growth and Promotes Tumor-Infiltrating Lymphocytes. Lucas A Horn, Tiha M Long, +2 authors, Ryan Atkinson, Virginia Clements, Suzanne Ostrand-Rosenberg. less Cancer Immunol Res, 2017 Nov 11; 6(1). PMID: 29122838 Free PMC article.
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Radiation Exposure-Induced Changes in the Immune Cells and Immune Factors of Mice With or Without Primary Lung Tumor. Shuxian Pan, Jingjie Wang, +11 authors, Anqing Wu, Ziyang Guo, Ziyang Wang, Lijun Zheng, Yingchu Dai, Lin Zhu, Jing Nie, Tom K Hei, Guangming Zhou, Youchen Li, Bingyan Li, Wentao Hu. less Dose Response, 2020 Jun 04; 18(2). PMID: 32489339 Free PMC article.
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Increased effect of two-fraction radiotherapy in conjunction with IDO1 inhibition in experimental glioblastoma. Jonatan Ahlstedt, Elise Konradsson, Crister Ceberg, Henrietta Nittby Redebrandt. PLoS One, 2020 May 30; 15(5). PMID: 32469935 Free PMC article.
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Inhibitory checkpoints in human natural killer cells: IUPHAR Review 28. F R Mariotti, L Quatrini, +5 authors, E Munari, P Vacca, N Tumino, G Pietra, M C Mingari, L Moretta. less Br J Pharmacol, 2020 Apr 27; 177(13). PMID: 32335915 Free PMC article. Review.
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ATR inhibitor AZD6738 enhances the antitumor activity of radiotherapy and immune checkpoint inhibitors by potentiating the tumor immune microenvironment in hepatocellular carcinoma. Hailong Sheng, Yan Huang, +10 authors, Yazhi Xiao, Zhenru Zhu, Mengying Shen, Peitao Zhou, Zeqin Guo, Jian Wang, Hui Wang, Wencong Dai, Wanjun Zhang, Jingyuan Sun, Chuanhui Cao. less J Immunother Cancer, 2020 May 29; 8(1). PMID: 32461345 Free PMC article.
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A review of radiation-induced lymphopenia in patients with esophageal cancer: an immunological perspective for radiotherapy. Xin Wang, Peiliang Wang, +3 authors, Zongxing Zhao, Qingfeng Mao, Jinming Yu, Minghuan Li. less Ther Adv Med Oncol, 2020 Jun 11; 12. PMID: 32518598 Free PMC article. Review.
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Anti-PD-L1 (atezolizumab) as an immune primer and concurrently with extended-field chemoradiotherapy for node-positive locally advanced cervical cancer. Jyoti Mayadev, Dmitriy Zamarin, +4 authors, Wei Deng, Heather Lankes, Roisin O'Cearbhaill, Carol A Aghajanian, Russell Schilder. less Int J Gynecol Cancer, 2019 Dec 25; 30(5). PMID: 31871115 Free PMC article.
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Immune Checkpoint Inhibitors in Hepatocellular Cancer: Current Understanding on Mechanisms of Resistance and Biomarkers of Response to Treatment. Amblessed E Onuma, Hongji Zhang, +3 authors, Hai Huang, Terence M Williams, Anne Noonan, Allan Tsung. less Gene Expr, 2020 Apr 29; 20(1). PMID: 32340652 Free PMC article. Review.
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Combination treatment with radiotherapy and a novel oxidative phosphorylation inhibitor overcomes PD-1 resistance and enhances antitumor immunity. Dawei Chen, Hampartsoum B Barsoumian, +11 authors, Grant Fischer, Liangpeng Yang, Vivek Verma, Ahmed I Younes, Yun Hu, Fatemeh Masropour, Katherine Klein, Christopher Vellano, Joseph Marszalek, Michael Davies, Maria Angelica Cortez, James Welsh. less J Immunother Cancer, 2020 Jun 26; 8(1). PMID: 32581056 Free PMC article.
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Immunomodulation of NK Cells by Ionizing Radiation. Jiarui Chen, Xingyu Liu, +7 authors, Zihang Zeng, Jiali Li, Yuan Luo, Wenjie Sun, Yan Gong, Junhong Zhang, Qiuji Wu, Conghua Xie. less Front Oncol, 2020 Jul 03; 10. PMID: 32612950 Free PMC article. Review.
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The impact of immunotherapy on the survival of pancreatic adenocarcinoma patients who do not receive definitive surgery of the tumor. Saber Amin, Michael Baine, +2 authors, Jane Meza, Morshed Alam, Chi Lin. less Clin Transl Radiat Oncol, 2020 Jul 03; 24. PMID: 32613090 Free PMC article.
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Radiotherapy-immunotherapy combinations - perspectives and challenges. Michele Mondini, Antonin Levy, +2 authors, Lydia Meziani, Fabien Milliat, Eric Deutsch. less Mol Oncol, 2020 Mar 01; 14(7). PMID: 32112478 Free PMC article. Review.
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Effect of Pembrolizumab After Stereotactic Body Radiotherapy vs Pembrolizumab Alone on Tumor Response in Patients With Advanced Non-Small Cell Lung Cancer: Results of the PEMBRO-RT Phase 2 Randomized Clinical Trial. Willemijn S M E Theelen, Heike M U Peulen, +9 authors, Ferry Lalezari, Vincent van der Noort, Jeltje F de Vries, Joachim G J V Aerts, Daphne W Dumoulin, Idris Bahce, Anna-Larissa N Niemeijer, Adrianus J de Langen, Kim Monkhorst, Paul Baas. less JAMA Oncol, 2019 Jul 12; 5(9). PMID: 31294749 Free PMC article. Highly Cited.
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Low Lymphocyte Count Is Associated With Radiotherapy Parameters and Affects the Outcomes of Esophageal Squamous Cell Carcinoma Patients. Xin Wang, Zongxing Zhao, +3 authors, Peiliang Wang, Xiaotao Geng, Liqiong Zhu, Minghuan Li. less Front Oncol, 2020 Jul 14; 10. PMID: 32656085 Free PMC article.
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Chemoradioimmunotherapy of inoperable stage III non-small cell lung cancer: immunological rationale and current clinical trials establishing a novel multimodal strategy. Lukas Käsmann, Chukwuka Eze, +6 authors, Julian Taugner, Olarn Roengvoraphoj, Maurice Dantes, Nina-Sophie Schmidt-Hegemann, Sanziana Schiopu, Claus Belka, Farkhad Manapov. less Radiat Oncol, 2020 Jul 11; 15(1). PMID: 32646443 Free PMC article. Review.
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Safety and Efficacy of Pembrolizumab With Chemoradiotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma: A Phase IB Study. Steven F Powell, Kathryn A Gold, +15 authors, Mark M Gitau, Christopher J Sumey, Michele M Lohr, Steven C McGraw, Ryan K Nowak, Ashley W Jensen, Miran J Blanchard, Christopher D Fischer, Julie Bykowski, Christie A Ellison, Lora J Black, Paul A Thompson, Juan L Callejas-Valera, John H Lee, Ezra E W Cohen, William C Spanos. less J Clin Oncol, 2020 Jun 02; 38(21). PMID: 32479189 Free PMC article.
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Radiation Dose Escalation is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance Local and Distant Antitumor Effect in Murine Osteosarcoma. Wataru Takenaka, Yutaka Takahashi, +6 authors, Keisuke Tamari, Kazumasa Minami, Shohei Katsuki, Yuji Seo, Fumiaki Isohashi, Masahiko Koizumi, Kazuhiko Ogawa. less Cancers (Basel), 2020 Jun 18; 12(6). PMID: 32545427 Free PMC article.
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Interrogating the immune-modulating roles of radiation therapy for a rational combination with immune-checkpoint inhibitors in treating pancreatic cancer. Kenji Fujiwara, May Tun Saung, +15 authors, Hao Jing, Brian Herbst, MacKenzie Zarecki, Stephen Muth, Annie Wu, Elaine Bigelow, Linda Chen, Keyu Li, Neolle Jurcak, Alex B Blair, Ding Ding, Michael Wichroski, Jordan Blum, Nathan Cheadle, Jennifer Koenitzer, Lei Zheng. less J Immunother Cancer, 2020 Jul 18; 8(2). PMID: 32675194 Free PMC article.
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Immune Checkpoint Inhibitors and Radiotherapy in NSCLC Patients: Not Just a Fluke. Lorenzo Belluomini, Francesco Fiorica, Antonio Frassoldati. Oncol Ther, 2020 Jul 24; 7(1). PMID: 32700194 Free PMC article.
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SBRT combined with PD-1/PD-L1 inhibitors in NSCLC treatment: a focus on the mechanisms, advances, and future challenges. Yu Chen, Min Gao, +2 authors, Zhaoqin Huang, Jinming Yu, Xiangjiao Meng. less J Hematol Oncol, 2020 Jul 30; 13(1). PMID: 32723363 Free PMC article. Review.
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Whole-brain Radiation and Pembrolizumab Treatment for a Non-small-cell Lung Cancer Patient with Meningeal Carcinomatosis Lacking Driver Oncogenes Led to a Long-term Survival. Koki Nakashima, Yoshiki Demura, +5 authors, Masahiro Oi, Mio Tabata, Toshihiko Tada, Kohei Shiozaki, Masaya Akai, Tamotsu Ishizuka. less Intern Med, 2020 Mar 13; 59(11). PMID: 32161221 Free PMC article.
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Significant benefits of pembrolizumab in treating refractory advanced pulmonary sarcomatoid carcinoma: A case report. Ping Chen, Min Yu, +5 authors, Ji-Liang Zhang, Wei-Yong Chen, Li Zhu, Yue Song, Cheng-Yi Jiang, Shuang Zhang. less World J Clin Cases, 2020 Aug 04; 8(13). PMID: 32742998 Free PMC article.
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Cost-effectiveness analysis of salvage therapies in locoregional previously irradiated head and neck cancer. HaYeon Kim, John A Vargo, +6 authors, Sushil Beriwal, David A Clump, James P Ohr, Robert L Ferris, Dwight E Heron, M Saiful Huq, Kenneth J Smith. less Head Neck, 2018 Mar 15; 40(8). PMID: 29537684 Free PMC article.
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A Multi-institutional Comparison of SBRT and IMRT for Definitive Reirradiation of Recurrent or Second Primary Head and Neck Cancer. John A Vargo, Matthew C Ward, +21 authors, Jimmy J Caudell, Nadeem Riaz, Neal E Dunlap, Derek Isrow, Sara J Zakem, Joshua Dault, Musaddiq J Awan, Kristin A Higgins, Comron Hassanadeh, Jonathan J Beitler, Chandana A Reddy, Samuel Marcrom, Drexell H Boggs, James A Bonner, Min Yao, Mitchell Machtay, Farzan Siddiqui, Andy M Trotti, Nancy Y Lee, Shlomo A Koyfman, Robert L Ferris, Dwight E Heron. less Int J Radiat Oncol Biol Phys, 2017 Sep 14; 100(3). PMID: 28899556 Free PMC article.
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Severe thromboembolic phenomenon in the setting of pseudoprogression of melanoma brain metastases in response to combination immunotherapy. Matthew C Perez, Hsiang-Hsuan M Yu, Joseph Markowitz. BMJ Case Rep, 2018 Aug 16; 2018. PMID: 30108120 Free PMC article.
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Association of tumour and stroma PD-1, PD-L1, CD3, CD4 and CD8 expression with DCB and OS to nivolumab treatment in NSCLC patients pre-treated with chemotherapy. Anna-Larissa Nadia Niemeijer, Sara Sahba, +3 authors, Egbert Frederik Smit, Birgit Ilja Lissenberg-Witte, Adrianus Johannes de Langen, Erik Thunnissen. less Br J Cancer, 2020 May 21; 123(3). PMID: 32433601 Free PMC article.
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Molecular Mechanisms and Potential Therapeutic Reversal of Pancreatic Cancer-Induced Immune Evasion. Li-Lian Gan, Ling-Wei Hii, +2 authors, Shew-Fung Wong, Chee-Onn Leong, Chun-Wai Mai. less Cancers (Basel), 2020 Jul 16; 12(7). PMID: 32664564 Free PMC article. Review.
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Modulation of Determinant Factors to Improve Therapeutic Combinations with Immune Checkpoint Inhibitors. Magalie Dosset, Elodie Lauret-Marie Joseph, Thaiz Rivera Vargas, Lionel Apetoh. Cells, 2020 Jul 28; 9(7). PMID: 32707692 Free PMC article. Review.
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An Immunophenotyping of Ovarian Cancer With Clinical and Immunological Significance. Kai Yang, Weiwei Zhao, +7 authors, Ge Lou, Zhiwei Rong, Huan Xu, Wenjie Wang, Wei Song, Yuqing Cai, Yan Hou, Kang Li. less Front Immunol, 2018 Apr 10; 9. PMID: 32793247 Free PMC article.
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Old dogs, new trick: classic cancer therapies activate cGAS. Seoyun Yum, Minghao Li, Zhijian J Chen. Cell Res, 2020 Jun 17; 30(8). PMID: 32541866 Free PMC article. Review.
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Research Progress and Existing Problems for Abscopal Effect. Di Wang, Xia Zhang, +6 authors, Yajie Gao, Xiaonan Cui, Yanqin Yang, Weifeng Mao, Minghuan Li, Bin Zhang, Jinming Yu. less Cancer Manag Res, 2020 Aug 18; 12. PMID: 32801902 Free PMC article. Review.
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Immune checkpoint inhibitor combination therapy for gastric cancer: Research progress. Xiaoxu Song, Weiwei Qi, +6 authors, Jing Guo, Libin Sun, Aiping Ding, Guanghui Zhao, Hui Li, Wensheng Qiu, Jing Lv. less Oncol Lett, 2020 Aug 18; 20(4). PMID: 32802168 Free PMC article. Review.
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Immune Checkpoint Imaging in Oncology: A Game Changer Toward Personalized Immunotherapy? Susanne Lütje, Georg Feldmann, +2 authors, Markus Essler, Peter Brossart, Ralph A Bundschuh. less J Nucl Med, 2020 Jan 12; 61(8). PMID: 31924724 Free PMC article. Review.
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The Promise of Combining Radiation Therapy With Immunotherapy. Justin C Jagodinsky, Paul M Harari, Zachary S Morris. Int J Radiat Oncol Biol Phys, 2020 Apr 27; 108(1). PMID: 32335187 Free PMC article. Review.
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Short-course radiotherapy promotes pro-inflammatory macrophages via extracellular vesicles in human rectal cancer. Victoria Stary, Brigitte Wolf, +8 authors, Daniela Unterleuthner, Julia List, Merjem Talic, Johannes Laengle, Andrea Beer, Johanna Strobl, Georg Stary, Helmut Dolznig, Michael Bergmann. less J Immunother Cancer, 2020 Aug 21; 8(2). PMID: 32817359 Free PMC article.
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Ultrathin metal-organic layer-mediated radiotherapy-radiodynamic therapy enhances immunotherapy of metastatic cancers. Kaiyuan Ni, Guangxu Lan, +5 authors, Christina Chan, Xiaopin Duan, Nining Guo, Samuel S Veroneau, Ralph R Weichselbaum, Wenbin Lin. less Matter, 2020 Aug 25; 1(5). PMID: 32832885 Free PMC article.
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Immune checkpoint blockade in solid organ tumours: Choice, dose and predictors of response. Vishal Navani, Moira C Graves, Nikola A Bowden, Andre Van Der Westhuizen. Br J Clin Pharmacol, 2020 May 10; 86(9). PMID: 32384184 Free PMC article. Review.
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Short-course radiation followed by mFOLFOX-6 plus avelumab for locally-advanced rectal adenocarcinoma. Ali Shamseddine, Youssef H Zeidan, +22 authors, Malek Kreidieh, Ibrahim Khalifeh, Rim Turfa, Joseph Kattan, Deborah Mukherji, Sally Temraz, Kholoud Alqasem, Rula Amarin, Tala Al Awabdeh, Samer Deeba, Faek Jamali, Issa Mohamad, Mousa Elkhaldi, Faiez Daoud, Mahmoud Al Masri, Ali Dabous, Ahmad Hushki, Omar Jaber, Clement Khoury, Ziad El Husseini, Maya Charafeddine, Monita Al Darazi, Fady Geara. less BMC Cancer, 2020 Sep 03; 20(1). PMID: 32873251 Free PMC article.
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Immune Checkpoint Inhibitors in pMMR Metastatic Colorectal Cancer: A Tough Challenge. Federica Marmorino, Alessandra Boccaccino, +2 authors, Marco Maria Germani, Alfredo Falcone, Chiara Cremolini. less Cancers (Basel), 2020 Aug 23; 12(8). PMID: 32824490 Free PMC article. Review.
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Combinatorial approach to cancer immunotherapy: strength in numbers. Anna E Vilgelm, Douglas B Johnson, Ann Richmond. J Leukoc Biol, 2016 Jun 04; 100(2). PMID: 27256570 Free PMC article. Review.
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Clinical Response to Anti-Programmed Death 1 After Response and Subsequent Progression on Anti-Programmed Death Ligand 1 Therapy. Emily H Castellanos, Emily Feld, +5 authors, Monica V Estrada, Melinda E Sanders, Pierre P Massion, Douglas B Johnson, Justin M Balko, Leora Horn. less JCO Precis Oncol, 2017 Aug 15; 1. PMID: 32913978 Free PMC article.
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Applying Precision Oncology Principles in Radiation Oncology. Sophia C Kamran, Kent W Mouw. JCO Precis Oncol, 2018 May 14; 2. PMID: 32914000 Free PMC article. Review.
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A liposomal RNA vaccine inducing neoantigen-specific CD4+ T cells augments the antitumor activity of local radiotherapy in mice. Nadja Salomon, Fulvia Vascotto, +9 authors, Abderaouf Selmi, Mathias Vormehr, Juliane Quinkhardt, Thomas Bukur, Barbara Schrörs, Martin Löewer, Mustafa Diken, Özlem Türeci, Ugur Sahin, Sebastian Kreiter. less Oncoimmunology, 2020 Sep 15; 9(1). PMID: 32923128 Free PMC article.
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Long-Lasting Response to Nivolumab for a Patient With Lynch Syndrome-Associated Lung Adenocarcinoma. Keita Masuzawa, Takanori Asakura, +8 authors, Shinnosuke Ikemura, Hiroyuki Yasuda, Ichiro Kawada, Sosuke Takaoka, Yuichiro Hayashi, Takeshi Nakajima, Masami Arai, Koichi Fukunaga, Kenzo Soejima. less JCO Precis Oncol, 2020 Sep 15; 4. PMID: 32923879 Free PMC article.
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Advances in immunotherapy for stage III non-small cell lung cancer: moving immune checkpoint inhibitors to the front lines concurrently with chemoradiotherapy? Toyoaki Hida, Teppei Yamaguchi. J Thorac Dis, 2020 Sep 19; 12(8). PMID: 32944372 Free PMC article.
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Radium-223 mechanism of action: implications for use in treatment combinations. Michael J Morris, Eva Corey, +5 authors, Theresa A Guise, James L Gulley, William Kevin Kelly, David I Quinn, Arne Scholz, George Sgouros. less Nat Rev Urol, 2019 Nov 13; 16(12). PMID: 31712765 Free PMC article. Review.
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Checkpoint Inhibition: Will Combination with Radiotherapy and Nanoparticle-Mediated Delivery Improve Efficacy? Purushottam Lamichhane, Neha P Amin, Manuj Agarwal, Narottam Lamichhane. Medicines (Basel), 2018 Oct 27; 5(4). PMID: 30360504 Free PMC article. Review.
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Radiotherapy as a New Player in Immuno-Oncology. Shang-Jui Wang, Bruce Haffty. Cancers (Basel), 2018 Dec 19; 10(12). PMID: 30558196 Free PMC article. Review.
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Review and current state of radiation therapy for locally advanced pancreatic adenocarcinoma. Adriana Blakaj, Stacey M Stein, Sajid A Khan, Kimberly L Johung. J Gastrointest Oncol, 2019 Jan 04; 9(6). PMID: 30603121 Free PMC article. Review.
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Evaluation of combined anti-PD-1 immunotherapy and radiation therapy in a preclinical mouse model of pneumonitis and fibrosis. Derek Nichols, Theresa A Boyle, +6 authors, David Noyes, Kujtim Latifi, Vladimir Feygelman, Isabel Jackson, Zeljko Vujaskovic, Scott Antonia, Bradford A Perez. less J Thorac Dis, 2019 Jan 10; 10(11). PMID: 30622798 Free PMC article.
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Combining stereotactic body radiation therapy with immunotherapy: current data and future directions. Alexander J Lin, Michael Roach, Jeffrey Bradley, Clifford Robinson. Transl Lung Cancer Res, 2019 Feb 23; 8(1). PMID: 30788240 Free PMC article. Review.
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Combinatorial Approach to Improve Cancer Immunotherapy: Rational Drug Design Strategy to Simultaneously Hit Multiple Targets to Kill Tumor Cells and to Activate the Immune System. Shweta Joshi, Donald L Durden. J Oncol, 2019 Mar 12; 2019. PMID: 30853982 Free PMC article. Review.
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Harnessing Radiation Biology to Augment Immunotherapy for Glioblastoma. Karishma R Rajani, Lucas P Carlstrom, +3 authors, Ian F Parney, Aaron J Johnson, Arthur E Warrington, Terry C Burns. less Front Oncol, 2019 Mar 12; 8. PMID: 30854331 Free PMC article. Review.
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Compound-therapy based on cancer-immunity cycle: promising prospects for antitumor regimens. Dong Gao. Am J Cancer Res, 2019 Mar 25; 9(2). PMID: 30906623 Free PMC article. Review.
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Efficacy of immunotherapy in sarcomatoid lung cancer, a case report and literature review. Magda Palka Kotlowska, Ana Gómez Rueda, +6 authors, María Eugenia Olmedo, Amparo Benito, Almudena Santón Roldán, Maria Angeles Fernandez Méndez, Luis Gorospe, José Palacios, Pilar Garrido López. less Respir Med Case Rep, 2019 Apr 02; 26. PMID: 30931249 Free PMC article.
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Novel Approaches to Improve the Efficacy of Immuno-Radiotherapy. Maxim Shevtsov, Hiro Sato, Gabriele Multhoff, Atsushi Shibata. Front Oncol, 2019 Apr 04; 9. PMID: 30941308 Free PMC article. Review.
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Radiotherapy Both Promotes and Inhibits Myeloid-Derived Suppressor Cell Function: Novel Strategies for Preventing the Tumor-Protective Effects of Radiotherapy. Suzanne Ostrand-Rosenberg, Lucas A Horn, Nicholas G Ciavattone. Front Oncol, 2019 Apr 20; 9. PMID: 31001479 Free PMC article. Review.
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The rationale for including immune checkpoint inhibition into multimodal primary treatment concepts of head and neck cancer. Ingeborg Tinhofer, Volker Budach, Korinna Jöhrens, Ulrich Keilholz. Cancers Head Neck, 2016 Aug 10; 1. PMID: 31093338 Free PMC article. Review.
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Induction of the Abscopal Effect with Immunotherapy and Palliative Radiation in Metastatic Head and Neck Squamous Cell Carcinoma: A Case Report and Review of the Literature. Ashwin Shinde, Jennifer Novak, +2 authors, Morganna L Freeman, Scott Glaser, Arya Amini. less Cureus, 2019 May 23; 11(3). PMID: 31114720 Free PMC article.
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The Combination of Stereotactic Body Radiation Therapy and Immunotherapy in Primary Liver Tumors. Malek Kreidieh, Youssef H Zeidan, Ali Shamseddine. J Oncol, 2019 Jun 12; 2019. PMID: 31182960 Free PMC article. Review.
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The 6th R of Radiobiology: Reactivation of Anti-Tumor Immune Response. Jihane Boustani, Mathieu Grapin, +2 authors, Pierre-Antoine Laurent, Lionel Apetoh, Céline Mirjolet. less Cancers (Basel), 2019 Jun 23; 11(6). PMID: 31226866 Free PMC article. Review.
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Is the Blood an Alternative for Programmed Cell Death Ligand 1 Assessment in Non-Small Cell Lung Cancer? Emmanuel Acheampong, Isaac Spencer, +3 authors, Weitao Lin, Melanie Ziman, Michael Millward, Elin Gray. less Cancers (Basel), 2019 Jul 03; 11(7). PMID: 31262041 Free PMC article. Review.
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Gut Microbiota Shapes the Efficiency of Cancer Therapy. Weidong Ma, Qixing Mao, +3 authors, Wenjie Xia, Gaochao Dong, Changhua Yu, Feng Jiang. less Front Microbiol, 2019 Jul 12; 10. PMID: 31293523 Free PMC article. Highly Cited. Review.
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Emerging and Novel Treatments for Pituitary Tumors. Mirela Diana Ilie, Hélène Lasolle, Gérald Raverot. J Clin Med, 2019 Jul 28; 8(8). PMID: 31349718 Free PMC article. Review.
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Clinical and radiation dose-volume factors related to pneumonitis after treatment with radiation and durvalumab in locally advanced non-small cell lung cancer. Hiroto Inoue, Akira Ono, +14 authors, Takanori Kawabata, Nobuaki Mamesaya, Takahisa Kawamura, Haruki Kobayashi, Shota Omori, Kazushige Wakuda, Hirotsugu Kenmotsu, Tateaki Naito, Haruyasu Murakami, Kazuaki Yasui, Hirofumi Ogawa, Tsuyoshi Onoe, Masahiro Endo, Hideyuki Harada, Toshiaki Takahashi. less Invest New Drugs, 2020 Mar 05; 38(5). PMID: 32128667 Free PMC article.
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Immunotherapy in urothelial cancer, part 2: adjuvant, neoadjuvant, and adjunctive treatment. Steven S Yu, Leslie K Ballas, +3 authors, Eila C Skinner, Tanya B Dorff, Sarmad Sadeghi, David I Quinn. less Clin Adv Hematol Oncol, 2017 Jul 28; 15(7). PMID: 28749918 Free PMC article. Review.
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[Interleukin-12 over-expression in malignant melanoma B16 cells reduces programmed death-1 expression on T cells in mice with immune reconstitution]. Yanyouhong Liu, Hongling Xu, +2 authors, Nan Lai, Zike Yang, Shijun Kang. less Nan Fang Yi Ke Da Xue Xue Bao, 2020 Sep 09; 40(6). PMID: 32895201 Free PMC article.
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Persistent anti-NY-ESO-1-specific T cells and expression of differential biomarkers in a patient with metastatic gastric cancer benefiting from combined radioimmunotherapy treatment: a case report. Maysaloun Merhi, Afsheen Raza, +15 authors, Varghese Philipose Inchakalody, Kodappully S Siveen, Deepak Kumar, Fairooz Sahir, Sarra Mestiri, Shereena Hydrose, Niloofar Allahverdi, Munir Jalis, Allan Relecom, Lobna Al Zaidan, Mohamed Sir Elkhatim Hamid, Mai Mostafa, Abdul Rehman Zar Gul, Shahab Uddin, Mohammed Al Homsi, Said Dermime. less J Immunother Cancer, 2020 Sep 12; 8(2). PMID: 32913031 Free PMC article.
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Combined radiotherapy and immunotherapy in urothelial bladder cancer: harnessing the full potential of the anti-tumor immune response. Mame Daro-Faye, Wassim Kassouf, +4 authors, Luis Souhami, Gautier Marcq, Fabio Cury, Tamim Niazi, Paul Sargos. less World J Urol, 2020 Sep 12; 39(5). PMID: 32915313 Free PMC article. Review.
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Radiation recall pneumonitis induced by PD-1/PD-L1 blockades: mechanisms and therapeutic implications. Feifei Teng, Min Li, Jinming Yu. BMC Med, 2020 Sep 19; 18(1). PMID: 32943072 Free PMC article. Review.
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Expression and clinical significance of PD-L1, B7-H3, B7-H4 and VISTA in craniopharyngioma. Yuelong Wang, Jiaojiao Deng, +10 authors, Lin Wang, Tingyue Zhou, Jinlong Yang, Zerong Tian, Jinhao Yang, Hongxu Chen, Xin Tang, Shasha Zhao, Liangxue Zhou, Aiping Tong, Jianguo Xu. less J Immunother Cancer, 2020 Sep 23; 8(2). PMID: 32958683 Free PMC article.
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CD47/SIRPα blocking peptide identification and synergistic effect with irradiation for cancer immunotherapy. Hongfei Wang, Yixuan Sun, +11 authors, Xiuman Zhou, Chunxia Chen, Ling Jiao, Wanqiong Li, Shanshan Gou, Yanying Li, Jiangfeng Du, Guanyu Chen, Wenjie Zhai, Yahong Wu, Yuanming Qi, Yanfeng Gao. less J Immunother Cancer, 2020 Oct 07; 8(2). PMID: 33020240 Free PMC article.
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Retrospective analysis of safety and efficacy of anti-PD-1 therapy and radiation therapy in advanced melanoma: A bi-institutional study. Yvonne M Mowery, Kirtesh Patel, +9 authors, Mudit Chowdhary, Christel N Rushing, Kingshuk Roy Choudhury, Jared R Lowe, Adam C Olson, Amy J Wisdom, Joseph K Salama, Brent A Hanks, Mohammad K Khan, April K S Salama. less Radiother Oncol, 2019 Jun 30; 138. PMID: 31252292 Free PMC article.
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Hepatocellular Carcinoma-The Influence of Immunoanatomy and the Role of Immunotherapy. Keyur Patel, Ryan Lamm, +2 authors, Peter Altshuler, Hien Dang, Ashesh P Shah. less Int J Mol Sci, 2020 Sep 19; 21(18). PMID: 32942580 Free PMC article. Review.
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Host genetics and tumor environment determine the functional impact of neutrophils in mouse tumor models. Marit van Elsas, Jan Willem Kleinovink, +8 authors, Matthijs Moerland, Gary Feiss, Guillaume Beyrend, Ramon Arens, Hailiang Mei, Peter H Nibbering, Silvana M Jirka, Thorbald van Hall, Sjoerd H van der Burg. less J Immunother Cancer, 2020 Oct 02; 8(2). PMID: 32998952 Free PMC article.
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B7-H3 regulates KIF15-activated ERK1/2 pathway and contributes to radioresistance in colorectal cancer. Yanchao Ma, Shenghua Zhan, +7 authors, Huimin Lu, Ruoqin Wang, Yunyun Xu, Guangbo Zhang, Lei Cao, Tongguo Shi, Xueguang Zhang, Weichang Chen. less Cell Death Dis, 2020 Oct 05; 11(10). PMID: 33011740 Free PMC article.
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Tumor-draining lymph node is important for a robust abscopal effect stimulated by radiotherapy. Zachary S Buchwald, Tahseen H Nasti, +7 authors, Judong Lee, Christiane S Eberhardt, Andres Wieland, Se Jin Im, David Lawson, Walter Curran, Rafi Ahmed, Mohammad K Khan. less J Immunother Cancer, 2020 Oct 09; 8(2). PMID: 33028691 Free PMC article.
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Application and Prospects of Molecular Imaging in Immunotherapy. Weiqing Wang, Zhenhua Gao, +4 authors, Lu Wang, Jianing Li, Jinming Yu, Shumei Han, Xue Meng. less Cancer Manag Res, 2020 Oct 17; 12. PMID: 33061627 Free PMC article. Review.
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Inhibition of Immunosuppressive Tumors by Polymer-Assisted Inductions of Immunogenic Cell Death and Multivalent PD-L1 Crosslinking. Lian Li, Yachao Li, +5 authors, Chieh-Hsiang Yang, D Christopher Radford, Jiawei Wang, Margit Janát-Amsbury, Jindřich Kopeček, Jiyuan Yang. less Adv Funct Mater, 2020 Oct 20; 30(12). PMID: 33071706 Free PMC article.
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A Tumor-Immune Interaction Model for Synergistic Combinations of Anti PD-L1 and Ionizing Irradiation Treatment. Jong Hyuk Byun, In-Soo Yoon, +2 authors, Yong Dam Jeong, Sungchan Kim, Il Hyo Jung. less Pharmaceutics, 2020 Sep 04; 12(9). PMID: 32878065 Free PMC article.
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Immunotherapy in Corticotroph and Lactotroph Aggressive Tumors and Carcinomas: Two Case Reports and a Review of the Literature. Camille Duhamel, Mirela Diana Ilie, +7 authors, Henri Salle, Adjoa Sika Nassouri, Stephan Gaillard, Elise Deluche, Richard Assaker, Laurent Mortier, Christine Cortet, Gérald Raverot. less J Pers Med, 2020 Aug 23; 10(3). PMID: 32823651 Free PMC article.
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Addition of Radiotherapy to Immunotherapy: Effects on Outcome of Different Subgroups Using a Propensity Score Matching. Maike Trommer, Jaika Kinsky, +12 authors, Anne Adams, Martin Hellmich, Max Schlaak, Michael von Bergwelt-Baildon, Eren Celik, Johannes Rosenbrock, Janis Morgenthaler, Jan M Herter, Philipp Linde, Cornelia Mauch, Sebastian Theurich, Simone Marnitz, Christian Baues. less Cancers (Basel), 2020 Sep 02; 12(9). PMID: 32867046 Free PMC article.
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Targeting Myeloid-Derived Suppressor Cells in Cancer Immunotherapy. Yufei Wang, Anna Jia, +5 authors, Yujing Bi, Yuexin Wang, Qiuli Yang, Yejin Cao, Yan Li, Guangwei Liu. less Cancers (Basel), 2020 Sep 19; 12(9). PMID: 32942545 Free PMC article. Review.
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Intra-hepatic Abscopal Effect Following Radioembolization of Hepatic Metastases. Maciej Powerski, Ralph Drewes, +3 authors, Jazan Omari, Borna Relja, Alexey Surov, Maciej Pech. less Cardiovasc Intervent Radiol, 2020 Aug 19; 43(11). PMID: 32808201 Free PMC article.
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Mechanisms of resistance to immune checkpoint inhibitors and strategies to reverse drug resistance in lung cancer. Fang-Fei Qian, Bao-Hui Han. Chin Med J (Engl), 2020 Sep 25; 133(20). PMID: 32969861 Free PMC article. Review.
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Combinational Immunotherapy for Hepatocellular Carcinoma: Radiotherapy, Immune Checkpoint Blockade and Beyond. Yun Hua Lee, David Tai, +2 authors, Connie Yip, Su Pin Choo, Valerie Chew. less Front Immunol, 2020 Oct 30; 11. PMID: 33117354 Free PMC article. Review.
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Radiotherapy-Mediated Immunomodulation and Anti-Tumor Abscopal Effect Combining Immune Checkpoint Blockade. Xinrui Zhao, Chunlin Shao. Cancers (Basel), 2020 Oct 01; 12(10). PMID: 32992835 Free PMC article. Review.
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Investigating Radiotherapy Response in a Novel Syngeneic Model of Prostate Cancer. Charles M Haughey, Debayan Mukherjee, +14 authors, Rebecca E Steele, Amy Popple, Lara Dura-Perez, Adam Pickard, Mehjabin Patel, Suneil Jain, Paul B Mullan, Rich Williams, Pedro Oliveira, Niamh E Buckley, Jamie Honeychurch, Simon S McDade, Timothy Illidge, Ian G Mills, Sharon L Eddie. less Cancers (Basel), 2020 Oct 03; 12(10). PMID: 33003551 Free PMC article.
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Tumor Microenvironment as a Regulator of Radiation Therapy: New Insights into Stromal-Mediated Radioresistance. Varintra E Krisnawan, Jennifer A Stanley, Julie K Schwarz, David G DeNardo. Cancers (Basel), 2020 Oct 15; 12(10). PMID: 33050580 Free PMC article. Review.
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Combining radiotherapy and immunotherapy in definitive treatment of head and neck squamous cell carcinoma: review of current clinical trials. Gaber Plavc, Primoz Strojan. Radiol Oncol, 2020 Oct 17; 54(4). PMID: 33064670 Free PMC article. Review.
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Immune Activation in Patients with Locally Advanced Cervical Cancer Treated with Ipilimumab Following Definitive Chemoradiation (GOG-9929). Diane M Da Silva, Danielle M Enserro, +10 authors, Jyoti S Mayadev, Joseph G Skeate, Koji Matsuo, Huyen Q Pham, Heather A Lankes, Katherine M Moxley, Sharad A Ghamande, Yvonne G Lin, Russell J Schilder, Michael J Birrer, W Martin Kast. less Clin Cancer Res, 2020 Aug 21; 26(21). PMID: 32816895 Free PMC article.
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Converging focal radiation and immunotherapy in a preclinical model of triple negative breast cancer: contribution of VISTA blockade. Karsten A Pilones, Michal Hensler, +5 authors, Camille Daviaud, Jeffrey Kraynak, Jitka Fucikova, Lorenzo Galluzzi, Sandra Demaria, Silvia C Formenti. less Oncoimmunology, 2020 Nov 06; 9(1). PMID: 33150045 Free PMC article.
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Optimizing Radiation Therapy to Boost Systemic Immune Responses in Breast Cancer: A Critical Review for Breast Radiation Oncologists. Alice Y Ho, Jean L Wright, +19 authors, Rachel C Blitzblau, Robert W Mutter, Dan G Duda, Larry Norton, Aditya Bardia, Laura Spring, Steven J Isakoff, Jonathan H Chen, Clemens Grassberger, Jennifer R Bellon, Sushil Beriwal, Atif J Khan, Corey Speers, Samantha A Dunn, Alastair Thompson, Cesar A Santa-Maria, Ian E Krop, Elizabeth Mittendorf, Tari A King, Gaorav P Gupta. less Int J Radiat Oncol Biol Phys, 2020 May 18; 108(1). PMID: 32417409 Free PMC article. Review.
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Reprogramming the tumour microenvironment by radiotherapy: implications for radiotherapy and immunotherapy combinations. Madyson Colton, Eleanor J Cheadle, Jamie Honeychurch, Tim M Illidge. Radiat Oncol, 2020 Nov 06; 15(1). PMID: 33148287 Free PMC article. Review.
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Role of GLUT-1 in the Upregulation of PD-L1 Expression After Radiotherapy and Association of PD-L1 with Favourable Overall Survival in Hypopharyngeal Cancer. Li-Fang Shen, Shui-Hong Zhou, Yu Guo. Onco Targets Ther, 2020 Nov 12; 13. PMID: 33173312 Free PMC article.
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Exosomal PD-L1: New Insights Into Tumor Immune Escape Mechanisms and Therapeutic Strategies. Kaijian Zhou, Shu Guo, +2 authors, Fei Li, Qiang Sun, Guoxin Liang. less Front Cell Dev Biol, 2020 Nov 13; 8. PMID: 33178688 Free PMC article. Review.
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Immunomodulatory Effects of Radiotherapy. Sharda Kumari, Shibani Mukherjee, +3 authors, Debapriya Sinha, Salim Abdisalaam, Sunil Krishnan, Aroumougame Asaithamby. less Int J Mol Sci, 2020 Nov 05; 21(21). PMID: 33142765 Free PMC article. Review.
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The Resistance Mechanisms of Lung Cancer Immunotherapy. Fen Wang, Shubin Wang, Qing Zhou. Front Oncol, 2020 Nov 17; 10. PMID: 33194652 Free PMC article. Review.
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Eliminating Radiation Resistance of Non-Small Cell Lung Cancer by Dihydroartemisinin Through Abrogating Immunity Escaping and Promoting Radiation Sensitivity by Inhibiting PD-L1 Expression. Hai Zhang, Fei Zhou, +8 authors, Yingying Wang, Huikang Xie, Shilan Luo, Lu Meng, Bin Su, Ying Ye, Kailiang Wu, Yaping Xu, Xiaomei Gong. less Front Oncol, 2020 Nov 17; 10. PMID: 33194761 Free PMC article.
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A narrative review of synergistic drug administration in unresectable locally advanced non-small cell lung cancer: current landscape and future prospects in the era of immunotherapy. Shuyan Li, Xiao Chu, +2 authors, Luxi Ye, Jianjiao Ni, Zhengfei Zhu. less Transl Lung Cancer Res, 2020 Nov 20; 9(5). PMID: 33209628 Free PMC article. Review.
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Radiotherapy for non-small cell lung cancer in the immunotherapy era: the opportunity and challenge-a narrative review. Wu-Yan Xia, Wen Feng, +5 authors, Chen-Chen Zhang, Yu-Jia Shen, Qin Zhang, Wen Yu, Xu-Wei Cai, Xiao-Long Fu. less Transl Lung Cancer Res, 2020 Nov 20; 9(5). PMID: 33209631 Free PMC article. Review.
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Moving Forward in Cervical Cancer: Enhancing Susceptibility to DNA Repair Inhibition and Damage, an NCI Clinical Trials Planning Meeting Report. Matthew M Harkenrider, Merry Jennifer Markham, +5 authors, Don S Dizon, Anuja Jhingran, Ritu Salani, Ramy K Serour, Jean Lynn, Elise C Kohn. less J Natl Cancer Inst, 2020 Mar 29; 112(11). PMID: 32219419 Free PMC article.
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KLHL22 maintains PD-1 homeostasis and prevents excessive T cell suppression. Xiao Albert Zhou, Jiadong Zhou, +13 authors, Long Zhao, Guihui Yu, Jun Zhan, Chanyi Shi, Ruoshi Yuan, Yan Wang, Changfeng Chen, Wenjia Zhang, Donghao Xu, Yingjiang Ye, Weibin Wang, Zhanlong Shen, Wei Wang, Jiadong Wang. less Proc Natl Acad Sci U S A, 2020 Oct 29; 117(45). PMID: 33109719 Free PMC article.
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The Mechanisms of PD-L1 Regulation in Non-Small-Cell Lung Cancer (NSCLC): Which Are the Involved Players? Giuseppe Lamberti, Monia Sisi, +5 authors, Elisa Andrini, Arianna Palladini, Francesca Giunchi, Pier-Luigi Lollini, Andrea Ardizzoni, Francesco Gelsomino. less Cancers (Basel), 2020 Oct 30; 12(11). PMID: 33114576 Free PMC article. Review.
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Challenges in Combining Immunotherapy with Radiotherapy in Recurrent/Metastatic Head and Neck Cancer. Gaber Plavc, Tanja Jesenko, Miha Oražem, Primož Strojan. Cancers (Basel), 2020 Nov 05; 12(11). PMID: 33143094 Free PMC article. Review.
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Immunotherapy Moves to the Early-Stage Setting in Non-Small Cell Lung Cancer: Emerging Evidence and the Role of Biomarkers. Xabier Mielgo-Rubio, Virginia Calvo, +11 authors, Javier Luna, Jordi Remon, Margarita Martín, Pedro Berraondo, José Ramón Jarabo, Oliver Higuera, Esther Conde, Javier De Castro, Mariano Provencio, Florentino Hernando Trancho, Fernando López-Ríos, Felipe Couñago. less Cancers (Basel), 2020 Nov 26; 12(11). PMID: 33233705 Free PMC article. Review.
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Recent Advances in the Clinical Development of Immune Checkpoint Blockade Therapy for Mismatch Repair Proficient (pMMR)/non-MSI-H Metastatic Colorectal Cancer. James J Lee, Edward Chu. Clin Colorectal Cancer, 2018 Aug 04; 17(4). PMID: 30072278 Free PMC article. Review.
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A High-Throughput Immune-Oncology Screen Identifies EGFR Inhibitors as Potent Enhancers of Antigen-Specific Cytotoxic T-lymphocyte Tumor Cell Killing. Patrick H Lizotte, Ruey-Long Hong, +16 authors, Troy A Luster, Megan E Cavanaugh, Luke J Taus, Stephen Wang, Abha Dhaneshwar, Naomi Mayman, Aaron Yang, Meghana Kulkarni, Lauren Badalucco, Erica Fitzpatrick, Hsiang-Fong Kao, Mari Kuraguchi, Mark Bittinger, Paul T Kirschmeier, Nathanael S Gray, David A Barbie, Pasi A Jänne. less Cancer Immunol Res, 2018 Sep 23; 6(12). PMID: 30242021 Free PMC article.
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Combining PARP inhibition, radiation, and immunotherapy: A possible strategy to improve the treatment of cancer? Mathieu Césaire, Juliette Thariat, +3 authors, Serge M Candéias, Dinu Stefan, Yannick Saintigny, François Chevalier. less Int J Mol Sci, 2018 Nov 30; 19(12). PMID: 30487462 Free PMC article. Review.
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Immune checkpoint blockade for Merkel cell carcinoma: actual findings and unanswered questions. Marco Gallo, Valentina Guarnotta, +4 authors, Federica De Cicco, Manila Rubino, Antongiulio Faggiano, Annamaria Colao, NIKE Group. less J Cancer Res Clin Oncol, 2019 Jan 09; 145(2). PMID: 30617553 Review.
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Phase I/II trial of Durvalumab plus Tremelimumab and stereotactic body radiotherapy for metastatic head and neck carcinoma. Houda Bahig, Francine Aubin, +14 authors, John Stagg, Olguta Gologan, Olivier Ballivy, Eric Bissada, Felix-Phuc Nguyen-Tan, Denis Soulières, Louis Guertin, Edith Filion, Apostolos Christopoulos, Louise Lambert, Mustapha Tehfe, Tareck Ayad, Danielle Charpentier, Rahima Jamal, Philip Wong. less BMC Cancer, 2019 Jan 16; 19(1). PMID: 30642290 Free PMC article.
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Time for radioimmunotherapy: an overview to bring improvements in clinical practice. O Leaman Alcibar, D Candini, +9 authors, F López-Campos, M Albert Antequera, V Morillo Macías, A J Conde, A Rodríguez Pérez, A Hervás Morón, J Contreras Martínez, C Ferrer Albiach, S Navarro Aguilar, M E Rodríguez-Ruiz. less Clin Transl Oncol, 2019 Jan 16; 21(8). PMID: 30644044 Review.
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Overall survival according to immunotherapy and radiation treatment for metastatic non-small-cell lung cancer: a National Cancer Database analysis. Corey C Foster, David J Sher, +4 authors, Chad G Rusthoven, Vivek Verma, Michael T Spiotto, Ralph R Weichselbaum, Matthew Koshy. less Radiat Oncol, 2019 Jan 30; 14(1). PMID: 30691492 Free PMC article.
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Increased PD-L1 expression in radioresistant HNSCC cell lines after irradiation affects cell proliferation due to inactivation of GSK-3beta. Daniela Schulz, Irene Stancev, +7 authors, Antonio Sorrentino, Ayse-Nur Menevse, Philipp Beckhove, Gero Brockhoff, Matthias Günther Hautmann, Torsten Erich Reichert, Richard Josef Bauer, Tobias Ettl. less Oncotarget, 2019 Feb 08; 10(5). PMID: 30728908 Free PMC article.
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Therapeutic challenges and current immunomodulatory strategies in targeting the immunosuppressive pancreatic tumor microenvironment. Chin-King Looi, Felicia Fei-Lei Chung, +3 authors, Chee-Onn Leong, Shew-Fung Wong, Rozita Rosli, Chun-Wai Mai. less J Exp Clin Cancer Res, 2019 Apr 17; 38(1). PMID: 30987642 Free PMC article. Highly Cited. Review.
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Stereotactic Ablative Radiotherapy Combined with Immune Checkpoint Inhibitors Reboots the Immune Response Assisted by Immunotherapy in Metastatic Lung Cancer: A Systematic Review. Rodolfo Chicas-Sett, Ignacio Morales-Orue, +5 authors, Juan Castilla-Martinez, Juan Zafra-Martin, Andrea Kannemann, Jesus Blanco, Marta Lloret, Pedro C Lara. less Int J Mol Sci, 2019 May 06; 20(9). PMID: 31052488 Free PMC article. Systematic Review.
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Sustained partial remission of a metastatic NEN using off-label immunotherapy with pembrolizumab. Anna Kathrin Stüven, Bertram Wiedenmann. Oncotarget, 2019 May 31; 10(35). PMID: 31143376 Free PMC article.
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Optimizing radiotherapy with immune checkpoint blockade in hepatocellular carcinoma. Changhoon Choi, Gyu Sang Yoo, Won Kyung Cho, Hee Chul Park. World J Gastroenterol, 2019 Jun 07; 25(20). PMID: 31171886 Free PMC article. Review.
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Advances in engineering local drug delivery systems for cancer immunotherapy. Peter Abdou, Zejun Wang, +4 authors, Qian Chen, Amanda Chan, Daojia R Zhou, Vivienne Gunadhi, Zhen Gu. less Wiley Interdiscip Rev Nanomed Nanobiotechnol, 2020 Apr 08; 12(5). PMID: 32255276 Free PMC article. Review.
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[Immunotherapy Advances in Small Cell Lung Cancer]. Yangyang Xu, Ping Zhan, Yong Song. Zhongguo Fei Ai Za Zhi, 2020 Aug 06; 23(11). PMID: 32752583 Free PMC article. Review.
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Photon versus carbon ion irradiation: immunomodulatory effects exerted on murine tumor cell lines. Laura Hartmann, Philipp Schröter, +8 authors, Wolfram Osen, Daniel Baumann, Rienk Offringa, Mahmoud Moustafa, Rainer Will, Jürgen Debus, Stephan Brons, Stefan Rieken, Stefan B Eichmüller. less Sci Rep, 2020 Dec 11; 10(1). PMID: 33299018 Free PMC article.
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Immunostimulatory Effects of Radiotherapy for Local and Systemic Control of Melanoma: A Review. Junko Takahashi, Shinsuke Nagasawa. Int J Mol Sci, 2020 Dec 11; 21(23). PMID: 33297519 Free PMC article. Review.
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Rationale for concurrent chemoradiotherapy for patients with stage III non-small-cell lung cancer. John Conibear, AstraZeneca UK Limited. Br J Cancer, 2020 Dec 10; 123(Suppl 1). PMID: 33293671 Free PMC article. Review.
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Beyond chemoradiotherapy: improving treatment outcomes for patients with stage III unresectable non-small-cell lung cancer through immuno-oncology and durvalumab (Imfinzi®▼, AstraZeneca UK Limited). Priyanka Patel, Doraid Alrifai, +2 authors, Fiona McDonald, Martin Forster, AstraZeneca UK Limited. less Br J Cancer, 2020 Dec 10; 123(Suppl 1). PMID: 33293672 Free PMC article. Review.
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The future of personalised radiotherapy for head and neck cancer. Jimmy J Caudell, Javier F Torres-Roca, +5 authors, Robert J Gillies, Heiko Enderling, Sungjune Kim, Anupam Rishi, Eduardo G Moros, Louis B Harrison. less Lancet Oncol, 2017 May 01; 18(5). PMID: 28456586 Free PMC article. Review.
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Efficacy of Local Treatments for Hepatocellular Carcinoma Involving the Inferior Vena Cava and/or Right Atrium. Han Ah Lee, Chai Hong Rim. J Hepatocell Carcinoma, 2020 Dec 31; 7. PMID: 33376712 Free PMC article. Review.
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Toward precision immunotherapy using multiplex immunohistochemistry and in silico methods to define the tumor immune microenvironment. Samuel S Widodo, Ryan A Hutchinson, +8 authors, Yitong Fang, Stefano Mangiola, Paul J Neeson, Phillip K Darcy, Alexander D Barrow, Christopher M Hovens, Marija Dinevska, Stanley S Stylli, Theo Mantamadiotis. less Cancer Immunol Immunother, 2021 Jan 04; 70(7). PMID: 33389014 Review.
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Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination. Jiali Yu, Michael D Green, +37 authors, Shasha Li, Yilun Sun, Sara N Journey, Jae Eun Choi, Syed Monem Rizvi, Angel Qin, Jessica J Waninger, Xueting Lang, Zoey Chopra, Issam El Naqa, Jiajia Zhou, Yingjie Bian, Long Jiang, Alangoya Tezel, Jeremy Skvarce, Rohan K Achar, Merna Sitto, Benjamin S Rosen, Fengyun Su, Sathiya P Narayanan, Xuhong Cao, Shuang Wei, Wojciech Szeliga, Linda Vatan, Charles Mayo, Meredith A Morgan, Caitlin A Schonewolf, Kyle Cuneo, Ilona Kryczek, Vincent T Ma, Christopher D Lao, Theodore S Lawrence, Nithya Ramnath, Fei Wen, Arul M Chinnaiyan, Marcin Cieslik, Ajjai Alva, Weiping Zou. less Nat Med, 2021 Jan 06; 27(1). PMID: 33398162 Free PMC article.
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Reprogramming immunosuppressive myeloid cells by activated T cells promotes the response to anti-PD-1 therapy in colorectal cancer. Jing Chen, Hong-Wei Sun, +8 authors, Yan-Yan Yang, Hai-Tian Chen, Xing-Juan Yu, Wen-Chao Wu, Yi-Tuo Xu, Li-Lian Jin, Xiao-Jun Wu, Jing Xu, Limin Zheng. less Signal Transduct Target Ther, 2021 Jan 09; 6(1). PMID: 33414378 Free PMC article.
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Durvalumab and tremelimumab with or without stereotactic body radiation therapy in relapsed small cell lung cancer: a randomized phase II study. Suchita Pakkala, Kristin Higgins, +14 authors, Zhengjia Chen, Gabriel Sica, Conor Steuer, Chao Zhang, Guojing Zhang, Shuhua Wang, Mohammad S Hossain, Bassel Nazha, Tyler Beardslee, Fadlo R Khuri, Walter Curran, Sagar Lonial, Edmund K Waller, Suresh Ramalingam, Taofeek K Owonikoko. less J Immunother Cancer, 2021 Jan 12; 8(2). PMID: 33428583 Free PMC article.
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The promising role of radiotherapy in the treatment of advanced or metastatic renal cell carcinoma: a narrative review. Qinghong Wei, Hongmei He, +2 authors, Long Lv, Xiaoying Xu, Weibing Sun. less Transl Androl Urol, 2021 Jan 19; 9(6). PMID: 33457253 Free PMC article. Review.
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Optimal combination treatment regimens of vaccine and radiotherapy augment tumor-bearing host immunity. Fayun Zhang, Zifeng Zheng, +8 authors, Apurba Kumar Barman, Zihao Wang, Luyao Wang, Wenfeng Zeng, Luoyang Wang, Yan Qin, Asmita Pandey, Chunling Zhang, Wei Liang. less Commun Biol, 2021 Jan 21; 4(1). PMID: 33469123 Free PMC article.
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A narrative review of evolving roles of radiotherapy in advanced non-small cell lung cancer: from palliative care to active player. Yue Zhou, Fan Yu, +9 authors, Yang Zhao, Ya Zeng, Xi Yang, Li Chu, Xiao Chu, Yida Li, Liqing Zou, Tiantian Guo, Zhengfei Zhu, Jianjiao Ni. less Transl Lung Cancer Res, 2021 Jan 26; 9(6). PMID: 33489808 Free PMC article. Review.
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A phase I/II study of stereotactic radiotherapy and pembrolizumab for oligometastatic renal tumours (RAPPORT): Clinical trial protocol. David Pryor, Mathias Bressel, +16 authors, Nathan Lawrentschuk, Ben Tran, Jennifer Mooi, Jeremy Lewin, Arun Azad, Duncan Colyer, Nitika Neha, Mark Shaw, Sarat Chander, Paul Neeson, Daniel Moon, Katharine Cuff, Simon Wood, Declan G Murphy, Shahneen Sandhu, Sherene Loi, Shankar Siva. less Contemp Clin Trials Commun, 2021 Jan 26; 21. PMID: 33490707 Free PMC article.
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3,3'-Diindolylmethane Enhances Tumor Regression After Radiation Through Protecting Normal Cells to Modulate Antitumor Immunity. Lijun Li, Renxiang Chen, +3 authors, Yun-Tien Lin, Arslon Humayun, Albert J Fornace, Heng-Hong Li. less Adv Radiat Oncol, 2021 Jan 26; 6(1). PMID: 33490731 Free PMC article.
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Nanoparticle-Mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy. Xiaopin Duan, Christina Chan, Wenbin Lin. Angew Chem Int Ed Engl, 2018 Jul 18; 58(3). PMID: 30016571 Free PMC article. Review.
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Combining radiation therapy and immunotherapy for lung cancers: a narrative review. Chirag Modi, Lyudmyla Berim, +6 authors, Lauren Isserow, Jyoti Malhotra, Malini Patel, John Langenfeld, Joseph Aisner, Doaa Almeldin, Salma K Jabbour. less Shanghai Chest, 2021 Feb 02; 5. PMID: 33521559 Free PMC article.
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Radiation-induced eosinophils improve cytotoxic T lymphocyte recruitment and response to immunotherapy. Jia-Nan Cheng, Wen Luo, +12 authors, Chengdu Sun, Zheng Jin, Xianghua Zeng, Peter B Alexander, Zhihua Gong, Xin Xia, Xiaofang Ding, Shouxia Xu, Ping Zou, Yisong Y Wan, Qingzhu Jia, Qi-Jing Li, Bo Zhu. less Sci Adv, 2021 Jan 31; 7(5). PMID: 33514544 Free PMC article.
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Oxidized mitochondrial DNA sensing by STING signaling promotes the antitumor effect of an irradiated immunogenic cancer cell vaccine. Chunju Fang, Fei Mo, +7 authors, Li Liu, Jing Du, Min Luo, Ke Men, Feifei Na, Wei Wang, Hanshuo Yang, Xiawei Wei. less Cell Mol Immunol, 2020 May 14; 18(9). PMID: 32398808 Free PMC article.
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Radiation and Immunotherapy in Upper Gastrointestinal Cancers: The Current State of Play. Noel E Donlon, Robert Power, +3 authors, Conall Hayes, Maria Davern, John V Reynolds, Joanne Lysaght. less Int J Mol Sci, 2021 Jan 28; 22(3). PMID: 33499003 Free PMC article. Review.
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Radiotherapy-Immunotherapy Combination: How Will We Bridge the Gap Between Pre-Clinical Promise and Effective Clinical Delivery? Erminia Romano, Jamie Honeychurch, Timothy M Illidge. Cancers (Basel), 2021 Feb 04; 13(3). PMID: 33530329 Free PMC article. Review.
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X-change symposium: status and future of modern radiation oncology-from technology to biology. Stefanie Corradini, Maximilian Niyazi, +14 authors, Dirk Verellen, Vincenzo Valentini, Seán Walsh, Anca-L Grosu, Kirsten Lauber, Amato Giaccia, Kristian Unger, Jürgen Debus, Bradley R Pieters, Matthias Guckenberger, Suresh Senan, Wilfried Budach, Roland Rad, Julia Mayerle, Claus Belka. less Radiat Oncol, 2021 Feb 06; 16(1). PMID: 33541387 Free PMC article. Review.
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Targeting autophagy enhances atezolizumab-induced mitochondria-related apoptosis in osteosarcoma. Zhuochao Liu, Hongyi Wang, +6 authors, Chuanzhen Hu, Chuanlong Wu, Jun Wang, Fangqiong Hu, Yucheng Fu, Junxiang Wen, Weibin Zhang. less Cell Death Dis, 2021 Feb 10; 12(2). PMID: 33558476 Free PMC article.
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Metastatic Melanoma With Leptomeningeal Disease. Amanda M Marinova, Jennifer L Reilly, +2 authors, Victoria Wong, Stephanie Weiss, Anthony J Olszanski. less J Adv Pract Oncol, 2021 Feb 09; 12(1). PMID: 33552663 Free PMC article.
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Discovery of a new inhibitor targeting PD-L1 for cancer immunotherapy. Fengling Wang, Wenling Ye, +9 authors, Shuang Wang, Yongxing He, Haiyang Zhong, Yuwei Wang, Yongchang Zhu, Jianting Han, Zhitong Bing, Shaoping Ji, Huanxiang Liu, Xiaojun Yao. less Neoplasia, 2021 Feb 03; 23(3). PMID: 33529880 Free PMC article.
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Hypofractionated Low-Dose Radiotherapy Combined with Immune Checkpoint Inhibition in Metastatic Solid Tumors. Dongqing Li, Wenyu Zhu, +5 authors, Juying Zhou, Mingya Peng, Qian Geng, Xiaolin Pu, Mengjie Wang, Hua Jiang. less Onco Targets Ther, 2021 Feb 12; 14. PMID: 33568917 Free PMC article.
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Surgery after neoadjuvant immunotherapy in patients with resectable non-small cell lung cancer. Caroline Huynh, Logan A Walsh, Jonathan D Spicer. Transl Lung Cancer Res, 2021 Feb 12; 10(1). PMID: 33569337 Free PMC article. Review.
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Novel Combination Therapies for the Treatment of Bladder Cancer. Mei Peng, Di Xiao, +4 authors, Yizhi Bu, Jiahui Long, Xue Yang, Shuhe Lv, Xiaoping Yang. less Front Oncol, 2021 Feb 16; 10. PMID: 33585182 Free PMC article. Review.
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Immunotherapeutic advances in gastric cancer. Akira Yoneda, Tamotsu Kuroki, Susumu Eguchi. Surg Today, 2021 Feb 17; 51(11). PMID: 33590326 Review.
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Evaluation of antitumor immunity by a combination treatment of high-dose irradiation, anti-PDL1, and anti-angiogenic therapy in murine lung tumors. Jenny Ling-Yu Chen, Chun-Kai Pan, +5 authors, Yu-Sen Huang, Ching-Yi Tsai, Chun-Wei Wang, Yu-Li Lin, Sung-Hsin Kuo, Ming-Jium Shieh. less Cancer Immunol Immunother, 2020 Aug 08; 70(2). PMID: 32761424
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Immune landscape and therapeutic strategies: new insights into PD-L1 in tumors. Yuan Wei, Xiao Xiao, +2 authors, Xiang-Ming Lao, Limin Zheng, Dong-Ming Kuang. less Cell Mol Life Sci, 2020 Sep 18; 78(3). PMID: 32940722 Review.
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Enhance the Immune Checkpoint Inhibitors Efficacy with Radiotherapy Induced Immunogenic Cell Death: A Comprehensive Review and Latest Developments. Adrien Procureur, Audrey Simonaggio, +2 authors, Jean-Emmanuel Bibault, Stéphane Oudard, Yann-Alexandre Vano. less Cancers (Basel), 2021 Feb 12; 13(4). PMID: 33567530 Free PMC article. Review.
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Natural Killer Cells and Anti-Cancer Therapies: Reciprocal Effects on Immune Function and Therapeutic Response. Elisa C Toffoli, Abdolkarim Sheikhi, +6 authors, Yannick D Höppner, Pita de Kok, Mahsa Yazdanpanah-Samani, Jan Spanholtz, Henk M W Verheul, Hans J van der Vliet, Tanja D de Gruijl. less Cancers (Basel), 2021 Feb 13; 13(4). PMID: 33572396 Free PMC article. Review.
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A Novel Anti-PD-L1 Antibody Exhibits Antitumor Effects on Multiple Myeloma in Murine Models via Antibody-Dependent Cellular Cytotoxicity. Jae-Hee Ahn, Byung-Hyun Lee, +8 authors, Seong-Eun Kim, Bo-Eun Kwon, Hyunjin Jeong, Jong Rip Choi, Min Jung Kim, Yong Park, Byung Soo Kim, Dae Hee Kim, Hyun-Jeong Ko. less Biomol Ther (Seoul), 2020 Nov 04; 29(2). PMID: 33139584 Free PMC article.
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Abscopal Effect of Frozen Autograft Reconstruction Combined with an Immune Checkpoint Inhibitor Analyzed Using a Metastatic Bone Tumor Model. Noritaka Yonezawa, Hideki Murakami, +14 authors, Satoru Demura, Satoshi Kato, Shinji Miwa, Katsuhito Yoshioka, Kazuya Shinmura, Noriaki Yokogawa, Takaki Shimizu, Norihiro Oku, Ryo Kitagawa, Makoto Handa, Ryohei Annen, Yuki Kurokawa, Kazumi Fushimi, Eishiro Mizukoshi, Hiroyuki Tsuchiya. less Int J Mol Sci, 2021 Mar 07; 22(4). PMID: 33671258 Free PMC article.
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Biology of NSCLC: Interplay between Cancer Cells, Radiation and Tumor Immune Microenvironment. Slavisa Tubin, Mohammad K Khan, Seema Gupta, Branislav Jeremic. Cancers (Basel), 2021 Mar 07; 13(4). PMID: 33673332 Free PMC article. Review.
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KEYNOTE-975 study design: a Phase III study of definitive chemoradiotherapy plus pembrolizumab in patients with esophageal carcinoma. Manish A Shah, Jaafar Bennouna, +12 authors, Toshihiko Doi, Lin Shen, Ken Kato, Antoine Adenis, Harvey J Mamon, Markus Moehler, Xiaolong Fu, Byoung Chul Cho, Sonal Bordia, Pooja Bhagia, Chie-Schin Shih, Anjali Desai, Peter Enzinger. less Future Oncol, 2021 Feb 04; 17(10). PMID: 33533655 Free PMC article.
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Immune Checkpoint Inhibitors for Non-Small-Cell Lung Cancer with Brain Metastasis : The Role of Gamma Knife Radiosurgery. Min Ho Lee, Kyung-Rae Cho, +10 authors, Jung Won Choi, Doo-Sik Kong, Ho Jun Seol, Do-Hyun Nam, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Myung-Ju Ahn, Keunchil Park, Jung-Il Lee. less J Korean Neurosurg Soc, 2020 Dec 04; 64(2). PMID: 33267531 Free PMC article.
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Macrophages and microglia: the cerberus of glioblastoma. Alice Buonfiglioli, Dolores Hambardzumyan. Acta Neuropathol Commun, 2021 Mar 27; 9(1). PMID: 33766119 Free PMC article. Review.
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A combination of PD‑1/PD‑L1 inhibitors: The prospect of overcoming the weakness of tumor immunotherapy (Review). Xianbin Kong, Peng Lu, +8 authors, Chuanxin Liu, Yuzhu Guo, Yuying Yang, Yingying Peng, Fangyuan Wang, Zhichao Bo, Xiaoxin Dou, Haoyang Shi, Jingyan Meng. less Mol Med Rep, 2021 Mar 25; 23(5). PMID: 33760188 Free PMC article. Review.
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Neoadjuvant chemoradiation alters biomarkers of anticancer immunotherapy responses in locally advanced rectal cancer. Incheol Seo, Hye Won Lee, +6 authors, Sang Jun Byun, Jee Young Park, Hyeonji Min, Sung Hwan Lee, Ju-Seog Lee, Shin Kim, Sung Uk Bae. less J Immunother Cancer, 2021 Mar 12; 9(3). PMID: 33692216 Free PMC article.
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Radiotherapy as an immune checkpoint blockade combination strategy for hepatocellular carcinoma. Byung Min Lee, Jinsil Seong. World J Gastroenterol, 2021 Mar 30; 27(10). PMID: 33776363 Free PMC article. Review.
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The role of exosomes in tumour immunity under radiotherapy: eliciting abscopal effects? Tianwen Yin, Huixian Xin, Jinming Yu, Feifei Teng. Biomark Res, 2021 Apr 02; 9(1). PMID: 33789758 Free PMC article. Review.
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PD-L1 expression in recurrent head and neck squamous cell carcinoma. Alice Delafoy, Arnaud Uguen, +4 authors, Gilles Lemasson, Virginie Conan-Charlet, Olivier Pradier, François Lucia, Ulrike Schick. less Eur Arch Otorhinolaryngol, 2021 Apr 03; 279(1). PMID: 33796940
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Modeling Radioimmune Response-Current Status and Perspectives. Thomas Friedrich, Nicholas Henthorn, Marco Durante. Front Oncol, 2021 Apr 03; 11. PMID: 33796470 Free PMC article. Review.
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Impact of Postoperative Radiotherapy on Survival of Patients With de novo Stage IV Breast Cancer: A Population-Based Study From the SEER Database. Jie Zhang, Shiping Luo, +2 authors, Zhaozhen Qiu, Yuxiang Lin, Chuangui Song. less Front Oncol, 2021 Apr 06; 11. PMID: 33816261 Free PMC article.
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Survival Benefits of Anti-PD-1 Therapy in Combination With Radiotherapy in Chinese Melanoma Patients With Brain Metastasis. Shuang Wu, Chuanping Yuan, +4 authors, Lei Chen, Lanlan Guo, Yong Chen, Zhenwei Peng, Lixia Lu. less Front Oncol, 2021 Apr 06; 11. PMID: 33816300 Free PMC article.
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Molecular and Clinical Premises for the Combination Therapy Consisting of Radiochemotherapy and Immunotherapy in Non-Small Cell Lung Cancer Patients. Małgorzata Frąk, Paweł Krawczyk, Ewa Kalinka, Janusz Milanowski. Cancers (Basel), 2021 Apr 04; 13(6). PMID: 33799560 Free PMC article. Review.
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Improving Anti-PD-1/PD-L1 Therapy for Localized Bladder Cancer. Florus C de Jong, Vera C Rutten, Tahlita C M Zuiverloon, Dan Theodorescu. Int J Mol Sci, 2021 Apr 04; 22(6). PMID: 33802033 Free PMC article. Review.
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Emerging Trends for Radio-Immunotherapy in Rectal Cancer. Claudia Corrò, Valérie Dutoit, Thibaud Koessler. Cancers (Basel), 2021 Apr 04; 13(6). PMID: 33803620 Free PMC article. Review.
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Thinking Small: Small Molecules as Potential Synergistic Adjuncts to Checkpoint Inhibition in Melanoma. Alexander C Chacon, Alexa D Melucci, Shuyang S Qin, Peter A Prieto. Int J Mol Sci, 2021 Apr 04; 22(6). PMID: 33810078 Free PMC article. Review.
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Avelumab, a PD-L1 Inhibitor, in Combination with Hypofractionated Radiotherapy and the Abscopal Effect in Relapsed Refractory Multiple Myeloma. Dickran Kazandjian, Alexander Dew, +19 authors, Elizabeth Hill, Elizabeth Gil Ramirez, Candis Morrison, Esther Mena, Liza Lindenberg, Constance Yuan, Irina Maric, Hao-Wei Wang, Katherine Calvo, Alina Dulau-Florea, Joseph Roswarski, Michael Emanuel, Raul Braylan, Baris Turkbey, Peter Choyke, Kevin Camphausen, Maryalice Stetler-Stevenson, Seth M Steinberg, William D Figg, Jennifer C Jones. less Oncologist, 2021 Feb 09; 26(4). PMID: 33554406 Free PMC article.
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An inhibitor of programmed death ligand 1 enhances natural killer cell-mediated immunity against malignant melanoma cells. Young Shin Lee, Woong Heo, +8 authors, Ho-Jung Choi, Hae-Ryung Cho, Ji Ho Nam, Yong Gan Ki, Hong-Rae Lee, Woo-Chang Son, You-Soo Park, Chi-Dug Kang, Jaeho Bae. less PLoS One, 2021 Apr 02; 16(4). PMID: 33793576 Free PMC article.
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Hypofractionated stereotactic re-irradiation with pembrolizumab and bevacizumab in patients with recurrent high-grade gliomas: results from a phase I study. Solmaz Sahebjam, Peter A Forsyth, +21 authors, Nam D Tran, John A Arrington, Robert Macaulay, Arnold B Etame, Christine M Walko, Theresa Boyle, Edwin N Peguero, Michael Jaglal, Sepideh Mokhtari, Heiko Enderling, Natarajan Raghunand, Tyra Gatewood, Wendy Long, Jennifer L Dzierzeski, Brittany Evernden, Timothy Robinson, Melissa C Wicklund, Sungjune Kim, Zachary J Thompson, Dung-Tsa Chen, Prakash Chinnaiyan, Hsiang-Hsuan Michael Yu. less Neuro Oncol, 2020 Nov 12; 23(4). PMID: 33173935 Free PMC article.
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Impact of reirradiation, chemotherapy, and immunotherapy on survival of patients with recurrent lung cancer: A single-center retrospective analysis. Brane Grambozov, Romana Wass, +6 authors, Markus Stana, Sabine Gerum, Josef Karner, Gerd Fastner, Michael Studnicka, Felix Sedlmayer, Franz Zehentmayr. less Thorac Cancer, 2021 Feb 16; 12(8). PMID: 33586228 Free PMC article.
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Toxicity Profile of Combining PD-1/PD-L1 Inhibitors and Thoracic Radiotherapy in Non-Small Cell Lung Cancer: A Systematic Review. Butuo Li, Chao Jiang, +5 authors, Linlin Pang, Bing Zou, Mingjun Ding, Xindong Sun, Jinming Yu, Linlin Wang. less Front Immunol, 2021 Apr 17; 12. PMID: 33859637 Free PMC article. Systematic Review.
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Optimizing the Treatment Schedule of Radiotherapy Combined With Anti-PD-1/PD-L1 Immunotherapy in Metastatic Cancers. Yuehong Kong, Yifu Ma, +3 authors, Xiangrong Zhao, Jie Pan, Zhi Xu, Liyuan Zhang. less Front Oncol, 2021 Apr 17; 11. PMID: 33859942 Free PMC article. Systematic Review.
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Curative-Intent Treatment with Durvalumab in Early-Stage Cancers. Giovanni Melillo, Vikram Chand, +2 authors, Alejandro Yovine, Ashok Gupta, Cristian Massacesi. less Adv Ther, 2021 Apr 22; 38(6). PMID: 33881745 Free PMC article. Review.
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Integration of radiotherapy with anti-PD-1 antibody for the treatment of intrahepatic or hilar cholangiocarcinoma: reflection from four cases. Qianqian Zhao, Yixing Chen, +4 authors, Shisuo Du, Xinrong Yang, Yanling Chen, Yuan Ji, Zhaochong Zeng. less Cancer Biol Ther, 2021 Mar 17; 22(3). PMID: 33722163 Free PMC article.
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Complete Pathologic Response After Concurrent Treatment with Pembrolizumab and Radiotherapy in Metastatic Colorectal Cancer: A Case Report. Jian Yang, Feng Bi, Hongfeng Gou. Onco Targets Ther, 2021 Apr 22; 14. PMID: 33880034 Free PMC article.
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Is immunotherapy in the future of therapeutic management of sarcomas? Ottavia Clemente, Alessandro Ottaiano, +9 authors, Giuseppe Di Lorenzo, Alessandra Bracigliano, Sabrina Lamia, Lucia Cannella, Antonio Pizzolorusso, Massimiliano Di Marzo, Mariachiara Santorsola, Annarosaria De Chiara, Flavio Fazioli, Salvatore Tafuto. less J Transl Med, 2021 Apr 28; 19(1). PMID: 33902630 Free PMC article. Review.
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Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose? Sandra Demaria, Chandan Guha, +11 authors, Jonathan Schoenfeld, Zachary Morris, Arta Monjazeb, Andrew Sikora, Marka Crittenden, Stephen Shiao, Samir Khleif, Seema Gupta, Silvia Chiara Formenti, Bhadrasain Vikram, C Norman Coleman, Mansoor M Ahmed. less J Immunother Cancer, 2021 Apr 09; 9(4). PMID: 33827904 Free PMC article. Review.
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Immune Modulation Plus Tumor Ablation: Adjuvants and Antibodies to Prime and Boost Anti-Tumor Immunity In Situ. Renske J E van den Bijgaart, Fabian Schuurmans, +3 authors, Jurgen J Fütterer, Marcel Verheij, Lenneke A M Cornelissen, Gosse J Adema. less Front Immunol, 2021 May 04; 12. PMID: 33936033 Free PMC article. Review.
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Novel Biomarkers of Dynamic Blood PD-L1 Expression for Immune Checkpoint Inhibitors in Advanced Non-Small-Cell Lung Cancer Patients. Qiao Yang, Mingjing Chen, +11 authors, Jiaoyang Gu, Kai Niu, Xianlan Zhao, Linpeng Zheng, Zihan Xu, Yongxin Yu, Feng Li, Lingxin Meng, Zhengtang Chen, Wenlei Zhuo, Luping Zhang, Jianguo Sun. less Front Immunol, 2021 May 04; 12. PMID: 33936103 Free PMC article.
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Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma. Sadna Budhu, Rachel Giese, +13 authors, Aditi Gupta, Kelly Fitzgerald, Roberta Zappasodi, Sara Schad, Daniel Hirschhorn, Luis Felipe Campesato, Olivier De Henau, Mathieu Gigoux, Cailian Liu, Gregory Mazo, Liang Deng, Christopher A Barker, Jedd D Wolchok, Taha Merghoub. less Cell Rep, 2021 Jan 14; 34(2). PMID: 33440157 Free PMC article.
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Emerging principles of brain immunology and immune checkpoint blockade in brain metastases. Jawad Fares, Ilya Ulasov, Peter Timashev, Maciej S Lesniak. Brain, 2021 Apr 25; 144(4). PMID: 33893488 Free PMC article. Review.
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Radiotherapy in the Era of Immunotherapy With a Focus on Non-Small-Cell Lung Cancer: Time to Revisit Ancient Dogmas? Jonathan Khalifa, Julien Mazieres, +2 authors, Carlos Gomez-Roca, Maha Ayyoub, Elizabeth Cohen-Jonathan Moyal. less Front Oncol, 2021 May 11; 11. PMID: 33968769 Free PMC article. Review.
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Interfaces between cellular responses to DNA damage and cancer immunotherapy. Domenic Pilger, Leonard W Seymour, Stephen P Jackson. Genes Dev, 2021 Apr 24; 35(9-10). PMID: 33888558 Free PMC article. Review.
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Effect of radiotherapy on T cell and PD-1 / PD-L1 blocking therapy in tumor microenvironment. Chen Chen, Yanlong Liu, Binbin Cui. Hum Vaccin Immunother, 2021 Jan 12; 17(6). PMID: 33428533 Free PMC article. Review.
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Temporal analysis of type 1 interferon activation in tumor cells following external beam radiotherapy or targeted radionuclide therapy. Justin C Jagodinsky, Won Jong Jin, +21 authors, Amber M Bates, Reinier Hernandez, Joseph J Grudzinski, Ian R Marsh, Ishan Chakravarty, Ian S Arthur, Luke M Zangl, Ryan J Brown, Erin J Nystuen, Sarah E Emma, Caroline Kerr, Peter M Carlson, Raghava N Sriramaneni, Jonathan W Engle, Eduardo Aluicio-Sarduy, Todd E Barnhart, Trang Le, KyungMann Kim, Bryan P Bednarz, Jamey P Weichert, Ravi B Patel, Zachary S Morris. less Theranostics, 2021 May 18; 11(13). PMID: 33995649 Free PMC article.
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STK11/LKB1 Mutations in NSCLC Are Associated with KEAP1/NRF2-Dependent Radiotherapy Resistance Targetable by Glutaminase Inhibition. Piyada Sitthideatphaiboon, Ana Galan-Cobo, +14 authors, Marcelo V Negrao, Xiao Qu, Alissa Poteete, Fahao Zhang, Diane D Liu, Whitney E Lewis, Haley N Kemp, Jeff Lewis, Waree Rinsurongkawong, Uma Giri, J Jack Lee, Jianjun Zhang, Jack A Roth, Stephen Swisher, John V Heymach. less Clin Cancer Res, 2020 Dec 17; 27(6). PMID: 33323404 Free PMC article.
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The regulation of immune checkpoints by the hypoxic tumor microenvironment. Min Hu, Yongfu Li, +5 authors, Yuting Lu, Miao Wang, Yingrui Li, Chaoying Wang, Qin Li, Hong Zhao. less PeerJ, 2021 May 21; 9. PMID: 34012727 Free PMC article.
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Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamous cell carcinoma. Rom Leidner, Marka Crittenden, +13 authors, Kristina Young, Hong Xiao, Yaping Wu, Marcus A Couey, Ashish A Patel, Allen C Cheng, Amber L Watters, Carlo Bifulco, George Morris, Lessli Rushforth, Shorin Nemeth, Walter J Urba, Michael Gough, R Bryan Bell. less J Immunother Cancer, 2021 May 09; 9(5). PMID: 33963014 Free PMC article.
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Intratumoral SIRPα-deficient macrophages activate tumor antigen-specific cytotoxic T cells under radiotherapy. Zhen Bian, Lei Shi, +3 authors, Koby Kidder, Ke Zen, Charlie Garnett-Benson, Yuan Liu. less Nat Commun, 2021 May 30; 12(1). PMID: 34050181 Free PMC article.
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Nanotechnology synergized immunoengineering for cancer. Deepak S Chauhan, Anupam Dhasmana, +6 authors, Partha Laskar, Rajendra Prasad, Nishant K Jain, Rohit Srivastava, Meena Jaggi, Subhash C Chauhan, Murali M Yallapu. less Eur J Pharm Biopharm, 2021 Mar 29; 163. PMID: 33774162 Free PMC article. Review.
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Immune Checkpoint Inhibitors in Prostate Cancer. Shobi Venkatachalam, Taylor R McFarland, Neeraj Agarwal, Umang Swami. Cancers (Basel), 2021 Jun 03; 13(9). PMID: 34063238 Free PMC article. Review.
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Combination Therapy, a Promising Approach to Enhance the Efficacy of Radionuclide and Targeted Radionuclide Therapy of Prostate and Breast Cancer. Tyrillshall S T Damiana, Simone U Dalm. Pharmaceutics, 2021 Jun 03; 13(5). PMID: 34067215 Free PMC article. Review.
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Repositioning Azelnidipine as a Dual Inhibitor Targeting CD47/SIRPα and TIGIT/PVR Pathways for Cancer Immuno-Therapy. Xiuman Zhou, Ling Jiao, +10 authors, Yuzhen Qian, Qingyu Dong, Yixuan Sun, Wei V Zheng, Wenshan Zhao, Wenjie Zhai, Lu Qiu, Yahong Wu, Hongfei Wang, Yanfeng Gao, Junhui Chen. less Biomolecules, 2021 Jun 03; 11(5). PMID: 34068552 Free PMC article.
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Combined with interventional therapy, immunotherapy can create a new outlook for tumor treatment. Tonglei Fang, Junyuan Xiao, +3 authors, Yiran Zhang, Haiyan Hu, Yueqi Zhu, Yingsheng Cheng. less Quant Imaging Med Surg, 2021 Jun 04; 11(6). PMID: 34079746 Free PMC article. Review.
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Research advances on the immune research and prospect of immunotherapy in pituitary adenomas. Ding Nie, Qiuyue Fang, +5 authors, Bin Li, Jianhua Cheng, Chuzhong Li, Songbai Gui, Yazhuo Zhang, Peng Zhao. less World J Surg Oncol, 2021 Jun 07; 19(1). PMID: 34090476 Free PMC article. Review.
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Radiotherapy and Cytokine Storm: Risk and Mechanism. Chen Zhang, Zhenzhen Liang, Shumei Ma, Xiaodong Liu. Front Oncol, 2021 Jun 08; 11. PMID: 34094967 Free PMC article. Review.
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Immunotherapy in non-small cell lung cancer: Update and new insights. Xabier Mielgo-Rubio, Eider Azkona Uribelarrea, Laura Quintanta Cortés, María Sereno Moyano. J Clin Transl Res, 2021 Jun 10; 7(1). PMID: 34104805 Free PMC article. Review.
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In situ delivery of iPSC-derived dendritic cells with local radiotherapy generates systemic antitumor immunity and potentiates PD-L1 blockade in preclinical poorly immunogenic tumor models. Takaaki Oba, Kenichi Makino, +7 authors, Ryutaro Kajihara, Toshihiro Yokoi, Ryoko Araki, Masumi Abe, Hans Minderman, Alfred E Chang, Kunle Odunsi, Fumito Ito. less J Immunother Cancer, 2021 May 30; 9(5). PMID: 34049930 Free PMC article.
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Adjuvant-free peptide vaccine targeting Clec9a on dendritic cells can induce robust antitumor immune response through Syk/IL-21 axis. Shanshan Gou, Shuai Wang, +10 authors, Wenwen Liu, Guanyu Chen, Dongyang Zhang, Jiangfeng Du, Zhongyi Yan, Hongfei Wang, Wenjie Zhai, Xinghua Sui, Yahong Wu, Yuanming Qi, Yanfeng Gao. less Theranostics, 2021 Jun 24; 11(15). PMID: 34158852 Free PMC article.
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Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads. Danielle M Lussier, Elise Alspach, +10 authors, Jeffrey P Ward, Alexander P Miceli, Daniele Runci, J Michael White, Cedric Mpoy, Cora D Arthur, Heather N Kohlmiller, Tyler Jacks, Maxim N Artyomov, Buck E Rogers, Robert D Schreiber. less Proc Natl Acad Sci U S A, 2021 Jun 09; 118(24). PMID: 34099555 Free PMC article.
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Radiotherapy and Renal Cell Carcinoma: A Continuing Saga. Despoina Spyropoulou, Panagiotis Tsiganos, +8 authors, Foteinos-Ioannis Dimitrakopoulos, Maria Tolia, Angelos Koutras, Dimitris Velissaris, Maria Lagadinou, Nikolaos Papathanasiou, Areti Gkantaifi, Haralabos Kalofonos, Dimitrios Kardamakis. less In Vivo, 2021 Apr 30; 35(3). PMID: 33910814 Free PMC article. Review.
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Cytoreductive Nephrectomy Promoted Abscopal Effect of Camrelizumab Combined With Radiotherapy for Metastatic Renal Cell Carcinoma: A Case Report and Review of the Literature. Min Wu, Jie Liu, +2 authors, Samuel Seery, Xue Meng, Jinbo Yue. less Front Immunol, 2021 Jul 03; 12. PMID: 34211459 Free PMC article. Review.
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NRG-HN003: Phase I and Expansion Cohort Study of Adjuvant Pembrolizumab, Cisplatin and Radiation Therapy in Pathologically High-Risk Head and Neck Cancer. Julie E Bauman, Jonathan Harris, +16 authors, Ravindra Uppaluri, Min Yao, Robert L Ferris, Josephine Chen, Richard C Jordan, Nikhil P Joshi, Srinivas Jujjuvaparu, Dukagjin M Blakaj, Christina Henson, Jawad Sheqwara, Loren K Mell, Neilayan Sen, David A Clump, Madhur K Garg, Emrullah Yilmaz, Pedro Torres-Saavedra, Quynh-Thu Le. less Cancers (Basel), 2021 Jul 03; 13(12). PMID: 34207599 Free PMC article.
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Neoadjuvant and Adjuvant Immunotherapy in Early-Stage Non-Small Cell Lung Cancer. Nikhil Shukla, Nasser Hanna. Lung Cancer (Auckl), 2021 Jul 09; 12. PMID: 34234606 Free PMC article. Review.
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Angiogenesis and immune checkpoint dual blockade in combination with radiotherapy for treatment of solid cancers: opportunities and challenges. Lingling Zhu, Xianzhe Yu, +6 authors, Li Wang, Jiewei Liu, Zihan Qu, Honge Zhang, Lu Li, Jiang Chen, Qinghua Zhou. less Oncogenesis, 2021 Jul 12; 10(7). PMID: 34247198 Free PMC article. Review.
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A Deep Insight Into CAR-T Cell Therapy in Non-Hodgkin Lymphoma: Application, Opportunities, and Future Directions. Faroogh Marofi, Heshu Sulaiman Rahman, +12 authors, Muhammad Harun Achmad, Klunko Nataliya Sergeevna, Wanich Suksatan, Walid Kamal Abdelbasset, Maria Vladimirovna Mikhailova, Navid Shomali, Mahboubeh Yazdanifar, Ali Hassanzadeh, Majid Ahmadi, Roza Motavalli, Yashwant Pathak, Sepideh Izadi, Mostafa Jarahian. less Front Immunol, 2021 Jul 13; 12. PMID: 34248965 Free PMC article. Review.
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Modulating the Radiation Response for Improved Outcomes in Breast Cancer. Andrea M Pesch, Lori J Pierce, Corey W Speers. JCO Precis Oncol, 2021 Jul 13; 5. PMID: 34250414 Free PMC article. Review.
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Incidence and risk factors for pneumonitis among patients with lung cancer who received immune checkpoint inhibitors after palliative thoracic radiotherapy. Satoshi Saito, Takanori Abe, +11 authors, Misaki Iino, Tomomi Aoshika, Yasuhiro Ryuno, Tomohiro Ohta, Mitsunobu Igari, Ryuta Hirai, Yu Kumazaki, Ou Yamaguchi, Kyoichi Kaira, Hiroshi Kagamu, Shin-Ei Noda, Shingo Kato. less J Radiat Res, 2021 Jun 15; 62(4). PMID: 34121123 Free PMC article.
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Heterogeneity of IFN-Mediated Responses and Tumor Immunogenicity in Patients with Cervical Cancer Receiving Concurrent Chemoradiotherapy. Jianzhou Chen, Chuangzhen Chen, +8 authors, Yizhou Zhan, Li Zhou, Jie Chen, Qingxin Cai, Yanxuan Wu, Zhihan Sui, Chengbing Zeng, Xiaolong Wei, Ruth Muschel. less Clin Cancer Res, 2021 Mar 27; 27(14). PMID: 33766815 Free PMC article.
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Overcoming Resistance to Immunotherapy in Head and Neck Cancer Using Radiation: A Review. Caressa Hui, Brittney Chau, +3 authors, Greg Gan, William Stokes, Sana D Karam, Arya Amini. less Front Oncol, 2021 Jul 20; 11. PMID: 34277390 Free PMC article. Review.
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The Abscopal Effect in the Era of Checkpoint Inhibitors. Ondřej Kodet, Kristýna Němejcova, +6 authors, Karolína Strnadová, Andrea Havlínová, Pavel Dundr, Ivana Krajsová, Jiří Štork, Karel Smetana, Lukáš Lacina. less Int J Mol Sci, 2021 Jul 21; 22(13). PMID: 34281259 Free PMC article. Review.
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A narrative review of combined stereotactic ablative radiotherapy and immunotherapy in metastatic non-small cell lung cancer. Zarique Z Akanda, Paul J Neeson, +5 authors, Thomas John, Stephen Barnett, Gerard G Hanna, Alistair Miller, Ross Jennens, Shankar Siva. less Transl Lung Cancer Res, 2021 Jul 24; 10(6). PMID: 34295676 Free PMC article. Review.
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A Prospective Trial Evaluating the Safety and Systemic Response From the Concurrent Use of Radiation Therapy with Checkpoint Inhibitor Immunotherapy in Metastatic Non-Small Cell Lung Cancer. Malcolm D Mattes, Timothy D Eubank, +4 authors, Mohammed Almubarak, Sijin Wen, Gary D Marano, Geraldine M Jacobson, Patrick C Ma. less Clin Lung Cancer, 2021 Feb 21; 22(4). PMID: 33608212 Free PMC article.
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Clinical retrospective study on the expression of the PD-L1 molecule in sporadic colorectal cancer and its correlation with K-ras gene mutations in Chinese patients. Jiasheng Xu, Wenpeng Zhao, +6 authors, Kaili Liao, Luxia Tu, Xiaozhen Jiang, Hua Dai, Yanqing Yu, Qiuying Xiong, Zhenfang Xiong. less Am J Transl Res, 2021 Jul 27; 13(6). PMID: 34306353 Free PMC article.
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Local Destruction of Tumors and Systemic Immune Effects. Karl-Göran Tranberg. Front Oncol, 2021 Jul 27; 11. PMID: 34307177 Free PMC article. Review.
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Myeloid-Derived Suppressor Cells: Implications in the Resistance of Malignant Tumors to T Cell-Based Immunotherapy. Houhui Shi, Kai Li, +2 authors, Yanghong Ni, Xiao Liang, Xia Zhao. less Front Cell Dev Biol, 2021 Aug 03; 9. PMID: 34336860 Free PMC article. Review.
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The role of PD-1/PD-L1 checkpoint in arsenic lung tumorigenesis. Wenhua Xu, Jiajun Cui, +2 authors, Linqing Wu, Caigu He, Gang Chen. less Toxicol Appl Pharmacol, 2021 Jun 25; 426. PMID: 34166680 Free PMC article.
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Time-sequential change in immune-related gene expression after irradiation in glioblastoma: next-generation sequencing analysis. Yi-Jun Kim, Kwangsoo Kim, +8 authors, Soo Yeon Seo, Juyeon Yu, Il Han Kim, Hak Jae Kim, Chul-Kee Park, Kye Hwa Lee, Junjeong Choi, Myung Seon Song, Jin Ho Kim. less Anim Cells Syst (Seoul), 2021 Aug 20; 25(4). PMID: 34408813 Free PMC article.
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Concurrent Sorafenib and Radiotherapy versus Radiotherapy Alone for Locally Advanced Hepatocellular Carcinoma: A Propensity-Matched Analysis. Chieh-Min Liu, Bing-Shen Huang, +6 authors, Yi-Hao Yen, Yu-Ming Wang, Eng-Yen Huang, Hsuan-Chih Hsu, Tzu-Ting Huang, Yao-Hsu Yang, Jen-Yu Cheng. less J Hepatocell Carcinoma, 2021 Aug 27; 8. PMID: 34434903 Free PMC article.
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Immune Checkpoints: Therapeutic Targets for Pituitary Tumors. Ding Nie, Yimeng Xue, +7 authors, Qiuyue Fang, Jianhua Cheng, Bin Li, Dawei Wang, Chuzhong Li, Songbai Gui, Yazhuo Zhang, Peng Zhao. less Dis Markers, 2021 Aug 28; 2021. PMID: 34447484 Free PMC article. Review.
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The Role of Immunotherapy in a Tolerogenic Environment: Current and Future Perspectives for Hepatocellular Carcinoma. Liliana Montella, Federica Sarno, +9 authors, Annamaria Ambrosino, Sergio Facchini, Maria D'Antò, Maria Maddalena Laterza, Morena Fasano, Ermelinda Quarata, Raffaele Angelo Nicola Ranucci, Lucia Altucci, Massimiliano Berretta, Gaetano Facchini. less Cells, 2021 Aug 28; 10(8). PMID: 34440678 Free PMC article. Review.
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Immunotherapy for HPV Malignancies. Maxwell Y Lee, Clint T Allen. Semin Radiat Oncol, 2021 Aug 31; 31(4). PMID: 34455991 Free PMC article. Review.
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Concurrent use of nivolumab and radiotherapy for patients with metastatic non-small cell lung cancer and renal cell carcinoma with oligometastatic disease progression on nivolumab. Jawaher Ansari, Ashraf Farrag, +7 authors, Arwa Ali, Mai Abdelgelil, Esam Murshid, Abdulaziz Alhamad, Muhammad Ali, Hidayath Ansari, Syed Hussain, John Glaholm. less Mol Clin Oncol, 2021 Sep 04; 15(4). PMID: 34476098 Free PMC article.
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Aggressive pituitary tumours and pituitary carcinomas. Gérald Raverot, Mirela Diana Ilie, +4 authors, Hélène Lasolle, Vincent Amodru, Jacqueline Trouillas, Frédéric Castinetti, Thierry Brue. less Nat Rev Endocrinol, 2021 Sep 09; 17(11). PMID: 34493834 Review.
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Phase I Trial of Cemiplimab, Radiotherapy, Cyclophosphamide, and Granulocyte Macrophage Colony-Stimulating Factor in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma. Hani Babiker, Irene Brana, +18 authors, Daruka Mahadevan, Taofeek Owonikoko, Emiliano Calvo, Danny Rischin, Victor Moreno, Kyriakos P Papadopoulos, Marka Crittenden, Silvia Formenti, Jordi Giralt, Pilar Garrido, Ainara Soria, Asunción Hervás-Morón, Kosalai Kal Mohan, Matthew Fury, Israel Lowy, Melissa Mathias, Minjie Feng, Jingjin Li, Elizabeth Stankevich. less Oncologist, 2021 May 05; 26(9). PMID: 33942954 Free PMC article.
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Pulsed Radiation Therapy to Improve Systemic Control of Metastatic Cancer. Kewen He, Hampartsoum B Barsoumian, +9 authors, Duygu Sezen, Nahum Puebla-Osorio, Ethan Y Hsu, Vivek Verma, Chike O Abana, Dawei Chen, Roshal R Patel, Meidi Gu, Maria Angelica Cortez, James W Welsh. less Front Oncol, 2021 Sep 10; 11. PMID: 34497773 Free PMC article.
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Hypofractionated Radiotherapy Upregulates Several Immune Checkpoint Molecules in Head and Neck Squamous Cell Carcinoma Cells Independently of the HPV Status While ICOS-L Is Upregulated Only on HPV-Positive Cells. Sebastian Wimmer, Lisa Deloch, +8 authors, Michael Hader, Anja Derer, Fridolin Grottker, Thomas Weissmann, Markus Hecht, Antoniu-Oreste Gostian, Rainer Fietkau, Benjamin Frey, Udo S Gaipl. less Int J Mol Sci, 2021 Sep 11; 22(17). PMID: 34502022 Free PMC article.
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Treatment of Cancer with Radio-Immunotherapy: What We Currently Know and What the Future May Hold. William Tyler Turchan, Sean P Pitroda, Ralph R Weichselbaum. Int J Mol Sci, 2021 Sep 11; 22(17). PMID: 34502479 Free PMC article. Review.
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Current Landscape of Immunotherapy in Breast Cancer: A Review. Sylvia Adams, Margaret E Gatti-Mays, +19 authors, Kevin Kalinsky, Larissa A Korde, Elad Sharon, Laleh Amiri-Kordestani, Harry Bear, Heather L McArthur, Elizabeth Frank, Jane Perlmutter, David B Page, Benjamin Vincent, Jennifer F Hayes, James L Gulley, Jennifer K Litton, Gabriel N Hortobagyi, Stephen Chia, Ian Krop, Julia White, Joseph Sparano, Mary L Disis, Elizabeth A Mittendorf. less JAMA Oncol, 2019 Apr 12; 5(8). PMID: 30973611 Free PMC article.
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Radiotherapy Combined with PD-1 Inhibition Increases NK Cell Cytotoxicity towards Nasopharyngeal Carcinoma Cells. Anna Makowska, Nora Lelabi, +5 authors, Christina Nothbaum, Lian Shen, Pierre Busson, Tram Thi Bao Tran, Michael Eble, Udo Kontny. less Cells, 2021 Sep 29; 10(9). PMID: 34572108 Free PMC article.
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Immune checkpoints and immunotherapy in non-small cell lung cancer: Novel study progression, challenges and solutions. Lin-Rui Ma, Jia-Xin Li, +5 authors, Ling Tang, Run-Ze Li, Jia-Shun Yang, Ao Sun, Elaine Lai-Han Leung, Pei-Yu Yan. less Oncol Lett, 2021 Oct 02; 22(5). PMID: 34594428 Free PMC article. Review.
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Role of BCLAF-1 in PD-L1 stabilization in response to ionizing irradiation. Zhao Ma, Han Wang, +6 authors, Fanbiao Meng, Yamei Han, Yefei Chen, Mingming Xiao, Hongjing Jiang, Zhentao Yu, Bo Xu. less Cancer Sci, 2021 Jul 13; 112(10). PMID: 34251713 Free PMC article.
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Phase II Single-arm Study of Durvalumab and Tremelimumab with Concurrent Radiotherapy in Patients with Mismatch Repair-proficient Metastatic Colorectal Cancer. Neil H Segal, Andrea Cercek, +35 authors, Geoffrey Ku, Abraham J Wu, Andreas Rimner, Danny N Khalil, Diane Reidy-Lagunes, John Cuaron, T Jonathan Yang, Martin R Weiser, Paul B Romesser, Zsofia K Stadler, Anna M Varghese, Karuna Ganesh, Rona Yaeger, Louise C Connell, David Faleck, Ghassan K Abou-Alfa, Kathleen C Mcauliffe, Pamela Vaiskauskas, Mark L Solter, Martinique Ogle, Matthew J Adamow, Aliya Holland, Pallavi Vedantam, Phillip Wong, Taha Merghoub, Efsevia Vakiani, Travis J Hollmann, Krishna Juluru, Joanne F Chou, Marinela Capanu, Joseph Erinjeri, Stephen Solomon, Yoshiya Yamada, Nancy Kemeny, Christopher H Crane, Leonard B Saltz. less Clin Cancer Res, 2021 Jan 29; 27(8). PMID: 33504552 Free PMC article.
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Parallels Between the Antiviral State and the Irradiated State. Heather M McGee, Ariel E Marciscano, +3 authors, Allison M Campbell, Arta M Monjazeb, Susan M Kaech, John R Teijaro. less J Natl Cancer Inst, 2020 Dec 01; 113(8). PMID: 33252657 Free PMC article.
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ZBP1-MLKL necroptotic signaling potentiates radiation-induced antitumor immunity via intratumoral STING pathway activation. Yuanqin Yang, Meng Wu, +15 authors, Dongqing Cao, Chao Yang, Jingsi Jin, Lingling Wu, Xiaochuan Hong, Wenwen Li, Lu Lu, Jinmei Li, Xinran Wang, Xiangjiao Meng, Zhen Zhang, Jinke Cheng, Youqiong Ye, Hui Xiao, Jinming Yu, Liufu Deng. less Sci Adv, 2021 Oct 07; 7(41). PMID: 34613770 Free PMC article.
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Anti-PD-1/Anti-PD-L1 Drugs and Radiation Therapy: Combinations and Optimization Strategies. Jihane Boustani, Benoît Lecoester, +4 authors, Jérémy Baude, Charlène Latour, Olivier Adotevi, Céline Mirjolet, Gilles Truc. less Cancers (Basel), 2021 Oct 14; 13(19). PMID: 34638376 Free PMC article. Review.
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Abscopal Effect of Radiotherapy Enhanced with Immune Checkpoint Inhibitors of Triple Negative Breast Cancer in 4T1 Mammary Carcinoma Model. Haa-Na Song, Hana Jin, +7 authors, Jung-Hoon Kim, In-Bong Ha, Ki-Mun Kang, Hoon-Sik Choi, Ho-Jin Jeong, Min-Young Kim, Hye-Jung Kim, Bae-Kwon Jeong. less Int J Mol Sci, 2021 Oct 14; 22(19). PMID: 34638817 Free PMC article.
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Melanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES). Peter Kar Han Lau, Breon Feran, +20 authors, Lorey Smith, Arian Lasocki, Ramyar Molania, Kortnye Smith, Alison Weppler, Christopher Angel, Damien Kee, Prachi Bhave, Belinda Lee, Richard J Young, Amir Iravani, Hanxian Aw Yeang, Ismael A Vergara, David Kok, Kate Drummond, Paul Joseph Neeson, Karen E Sheppard, Tony Papenfuss, Benjamin J Solomon, Shahneen Sandhu, Grant A McArthur. less J Immunother Cancer, 2021 Oct 10; 9(10). PMID: 34625515 Free PMC article.
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Immunotherapeutic Advances for NSCLC. Marco Massafra, Maria Ilenia Passalacqua, +6 authors, Vittorio Gebbia, Paolo Macrì, Chiara Lazzari, Vanesa Gregorc, Carmelo Buda, Giuseppe Altavilla, Mariacarmela Santarpia. less Biologics, 2021 Oct 23; 15. PMID: 34675481 Free PMC article. Review.
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Recent Progress in the Neoadjuvant Treatment Strategy for Locally Advanced Esophageal Cancer. Sicong Hou, Ziyin Pan, +2 authors, Xin Hao, Qinglei Hang, Yanbing Ding. less Cancers (Basel), 2021 Oct 24; 13(20). PMID: 34680311 Free PMC article. Review.
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Radiation-Induced Fibrotic Tumor Microenvironment Regulates Anti-Tumor Immune Response. Jae-Kyung Nam, Ji-Hee Kim, +3 authors, Min-Sik Park, Eun Ho Kim, Joon Kim, Yoon-Jin Lee. less Cancers (Basel), 2021 Oct 24; 13(20). PMID: 34680381 Free PMC article.
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Potentiating Antitumor Efficacy Through Radiation and Sustained Intratumoral Delivery of Anti-CD40 and Anti-PDL1. Hsuan-Chen Liu, Dixita I Viswanath, +16 authors, Federica Pesaresi, Yitian Xu, Licheng Zhang, Nicola Di Trani, Jesus Paez-Mayorga, Nathanael Hernandez, Yu Wang, Donald R Erm, Jeremy Ho, Antonia Susnjar, Xuewu Liu, Sandra Demaria, Shu-Hsia Chen, Bin S Teh, Edward Brian Butler, Corrine Ying Xuan Chua, Alessandro Grattoni. less Int J Radiat Oncol Biol Phys, 2020 Aug 10; 110(2). PMID: 32768562 Free PMC article.
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Current advances in immune checkpoint inhibitor combinations with radiation therapy or cryotherapy for breast cancer. Alice Y Ho, Shervin Tabrizi, Samantha A Dunn, Heather L McArthur. Breast Cancer Res Treat, 2021 Oct 30; 191(2). PMID: 34714450 Review.
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Advances in Combining Radiation and Immunotherapy in Breast Cancer. Anthony T Nguyen, Stephen L Shiao, Heather L McArthur. Clin Breast Cancer, 2021 Apr 04; 21(2). PMID: 33810972 Free PMC article. Review.
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Kickstarting Immunity in Cold Tumours: Localised Tumour Therapy Combinations With Immune Checkpoint Blockade. Elizabeth Appleton, Jehanne Hassan, +7 authors, Charleen Chan Wah Hak, Nanna Sivamanoharan, Anna Wilkins, Adel Samson, Masahiro Ono, Kevin J Harrington, Alan Melcher, Erik Wennerberg. less Front Immunol, 2021 Nov 05; 12. PMID: 34733287 Free PMC article. Review.
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Radiation Plus Anti-PD-1 Therapy for NSCLC Brain Metastases: A Retrospective Study. Guixiang Liao, Yuting Qian, +8 authors, Sumbal Arooj, Zhihong Zhao, Maosheng Yan, Zihuang Li, Hongli Yang, Tao Zheng, Gang Li, Xianming Li, Muhammad Khan. less Front Oncol, 2021 Nov 09; 11. PMID: 34745964 Free PMC article.
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Local, multimodal intralesional therapy renders distant brain metastases susceptible to PD-L1 blockade in a preclinical model of triple-negative breast cancer. Toshihiro Yokoi, Takaaki Oba, +2 authors, Ryutaro Kajihara, Scott I Abrams, Fumito Ito. less Sci Rep, 2021 Nov 11; 11(1). PMID: 34754037 Free PMC article.
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Carbon ion radiotherapy boosts anti-tumour immune responses by inhibiting myeloid-derived suppressor cells in melanoma-bearing mice. Heng Zhou, Pengfei Yang, +5 authors, Haining Li, Liying Zhang, Jin Li, Tianyi Zhang, Chengyan Sheng, Jufang Wang. less Cell Death Discov, 2021 Nov 05; 7(1). PMID: 34732697 Free PMC article.
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Immunosuppression in Glioblastoma: Current Understanding and Therapeutic Implications. Benjamin T Himes, Philipp A Geiger, +3 authors, Katayoun Ayasoufi, Adip G Bhargav, Desmond A Brown, Ian F Parney. less Front Oncol, 2021 Nov 16; 11. PMID: 34778089 Free PMC article. Review.
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Potential Molecular Targets in the Setting of Chemoradiation for Esophageal Malignancies. Salma K Jabbour, Terence M Williams, +16 authors, Mutlay Sayan, Eric D Miller, Jaffer A Ajani, Andrew C Chang, Norman Coleman, Wael El-Rifai, Michael Haddock, David Ilson, Daniel Jamorabo, Charles Kunos, Steven Lin, Geoffrey Liu, Pataje G Prasanna, Anil K Rustgi, Rosemary Wong, Bhadrasain Vikram, Mansoor M Ahmed. less J Natl Cancer Inst, 2020 Dec 23; 113(6). PMID: 33351071 Free PMC article. Review.
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Advances in locoregional therapy for hepatocellular carcinoma combined with immunotherapy and targeted therapy. Jian Xue, Hongbo Ni, +2 authors, Fan Wang, Ke Xu, Meng Niu. less J Interv Med, 2021 Nov 23; 4(3). PMID: 34805958 Free PMC article. Review.
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Efficacy of single-site radiotherapy plus PD-1 inhibitors vs PD-1 inhibitors for oligometastatic non-small cell lung cancer. Peiliang Wang, Tianwen Yin, +2 authors, Kaikai Zhao, Jinming Yu, Feifei Teng. less J Cancer Res Clin Oncol, 2021 Nov 24; 148(5). PMID: 34812931 Free PMC article.
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Immune checkpoint inhibition for pancreatic ductal adenocarcinoma: limitations and prospects: a systematic review. Hong-Bo Li, Zi-Han Yang, Qing-Qu Guo. Cell Commun Signal, 2021 Nov 26; 19(1). PMID: 34819086 Free PMC article. Review.
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Recent Research on Combination of Radiotherapy with Targeted Therapy or Immunotherapy in Head and Neck Squamous Cell Carcinoma: A Review for Radiation Oncologists. Daniel Tao Xing, Richard Khor, +3 authors, Hui Gan, Morikatsu Wada, Tai Ermongkonchai, Sweet Ping Ng. less Cancers (Basel), 2021 Nov 28; 13(22). PMID: 34830871 Free PMC article. Review.
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Prognostic implication of PD-L1 polymorphisms in non-small cell lung cancer treated with radiotherapy. Min Kyu Kang, Shin Yup Lee, +4 authors, Jin Eun Choi, Sook Kyung Do, Moon-June Cho, Jun-Sang Kim, Jae Yong Park. less Cancer Med, 2021 Oct 07; 10(22). PMID: 34612596 Free PMC article.
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Combined treatment of non-small cell lung cancer using radiotherapy and immunotherapy: challenges and updates. Shijie Shang, Jie Liu, +4 authors, Vivek Verma, Meng Wu, James Welsh, Jinming Yu, Dawei Chen. less Cancer Commun (Lond), 2021 Oct 19; 41(11). PMID: 34658186 Free PMC article. Review.
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B7-H3-targeted Radioimmunotherapy of Human Cancer. Benjamin B Kasten, Soldano Ferrone, Kurt R Zinn, Donald J Buchsbaum. Curr Med Chem, 2019 Mar 07; 27(24). PMID: 30836909 Free PMC article. Review.
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Favorable response to multimodal treatment in hepatocellular carcinoma with inferior vena cava and right atrial tumor thrombus and left adrenal gland metastasis: A case report and literature review. Ning Sun, Jialin Zhang, +3 authors, Baifeng Li, Ailin Li, Mutian Lv, Chengshuo Zhang. less Medicine (Baltimore), 2021 Dec 11; 100(49). PMID: 34889243 Free PMC article. Review.
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PD-1 Inhibitor Maintenance Therapy Combined Iodine-125 Seed Implantation Successfully Salvage Recurrent Cervical Cancer after CCRT: A Case Report. Guangchao Wei, Fuxin Guo, +4 authors, Ang Qu, Weijuan Jiang, Yuliang Jiang, Junjie Wang, Ping Jiang. less Curr Oncol, 2021 Dec 14; 28(6). PMID: 34898560 Free PMC article.
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Radiation-activated secretory proteins of Scgb1a1 + club cells increase the efficacy of immune checkpoint blockade in lung cancer. Yi Ban, Geoffrey J Markowitz, +8 authors, Yue Zou, Divya Ramchandani, Jeffrey Kraynak, Jianting Sheng, Sharrell B Lee, Stephen T C Wong, Nasser K Altorki, Dingcheng Gao, Vivek Mittal. less Nat Cancer, 2021 Dec 18; 2(9). PMID: 34917944 Free PMC article.
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Rationale and Design for a Multicenter, Phase II Study of Durvalumab Plus Concurrent Radiation Therapy in Locally Advanced Non-Small Cell Lung Cancer: The DOLPHIN Study (WJOG11619L). Motoko Tachihara, Kayoko Tsujino, +15 authors, Takeaki Ishihara, Hidetoshi Hayashi, Yuki Sato, Takayasu Kurata, Shunichi Sugawara, Isamu Okamoto, Shunsuke Teraoka, Koichi Azuma, Haruko Daga, Masafumi Yamaguchi, Takeshi Kodaira, Miyako Satouchi, Mototsugu Shimokawa, Nobuyuki Yamamoto, Kazuhiko Nakagawa, members of the West Japan Oncology Group (WJOG). less Cancer Manag Res, 2021 Dec 23; 13. PMID: 34934361 Free PMC article.
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Nivolumab and Stereotactic Radiosurgery for Patients With Breast Cancer Brain Metastases: A Nonrandomized, Open-Label Phase 1b Study. Kamran A Ahmed, Youngchul Kim, +19 authors, John A Arrington, Sungjune Kim, Michelle DeJesus, Aixa E Soyano, Avan J Armaghani, Ricardo L B Costa, Hung T Khong, Loretta S Loftus, Marilin Rosa, Jimmy J Caudell, Roberto Diaz, Timothy J Robinson, Arnold B Etame, Nam D Tran, Solmaz Sahebjam, Hatem H Soliman, Brian J Czerniecki, Peter A Forsyth, H Michael Yu, Hyo S Han. less Adv Radiat Oncol, 2021 Dec 23; 6(6). PMID: 34934864 Free PMC article.
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The Challenge to the Pathologist of PD-L1 Expression in Tumor Cells of Non-Small-Cell Lung Cancer-An Overview. Korinna Jöhrens, Josef Rüschoff. Curr Oncol, 2021 Dec 24; 28(6). PMID: 34940076 Free PMC article. Review.
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Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity. Yuzhu Hou, Hua L Liang, +19 authors, Xinshuang Yu, Zhida Liu, Xuezhi Cao, Enyu Rao, Xiaona Huang, Liangliang Wang, Lei Li, Jason Bugno, Yanbin Fu, Steven J Chmura, Wenjun Wu, Sean Z Luo, Wenxin Zheng, Ainhoa Arina, Jessica Jutzy, Anne R McCall, Everett E Vokes, Sean P Pitroda, Yang-Xin Fu, Ralph R Weichselbaum. less Sci Transl Med, 2021 Feb 26; 13(582). PMID: 33627484 Free PMC article.
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A case of primary malignant melanoma of the esophagogastric junction with abscopal effect after nivolumab administration. Takahisa Yamaguchi, Sachio Fushida, +8 authors, Jun Kinoshita, Hiroto Saito, Mari Shimada, Shiro Terai, Hideki Moriyama, Koichi Okamoto, Keishi Nakamura, Itasu Ninomiya, Noriyuki Inaki. less Surg Case Rep, 2021 Dec 10; 7(1). PMID: 34882298 Free PMC article.
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Combined Treatment with Immunotherapy-Based Strategies for MSS Metastatic Colorectal Cancer. Iosune Baraibar, Oriol Mirallas, +4 authors, Nadia Saoudi, Javier Ros, Francesc Salvà, Josep Tabernero, Elena Élez. less Cancers (Basel), 2021 Dec 25; 13(24). PMID: 34944931 Free PMC article. Review.
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Combination of Modern Radiotherapy and New Targeted Treatments for Breast Cancer Management. Arnaud Beddok, Paul Cottu, Alain Fourquet, Youlia Kirova. Cancers (Basel), 2021 Dec 25; 13(24). PMID: 34944978 Free PMC article. Review.
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Potential Reasons for Unresponsiveness to Anti-PD1 Immunotherapy in Young Patients with Advanced Melanoma. Devayani Machiraju, Sarah Schäfer, Jessica C Hassel. Life (Basel), 2021 Dec 25; 11(12). PMID: 34947849 Free PMC article. Review.
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The Research Progress of PD-1/PD-L1 Inhibitors Enhancing Radiotherapy Efficacy. Lu Wen, Fan Tong, +3 authors, Ruiguang Zhang, Lingjuan Chen, Yu Huang, Xiaorong Dong. less Front Oncol, 2021 Dec 28; 11. PMID: 34956911 Free PMC article. Review.
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Systemic Immune Activation and Responses of Irradiation to Different Metastatic Sites Combined With Immunotherapy in Advanced Non-Small Cell Lung Cancer. Min Wu, Jie Liu, +4 authors, Shihao Wu, Jingru Liu, Hui Wu, Jinming Yu, Xue Meng. less Front Immunol, 2022 Jan 01; 12. PMID: 34970277 Free PMC article.
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Modulation of the Human Pancreatic Ductal Adenocarcinoma Immune Microenvironment by Stereotactic Body Radiotherapy. Bradley N Mills, Haoming Qiu, +11 authors, Michael G Drage, Chunmo Chen, Jocelyn S Mathew, Jesse Garrett-Larsen, Jian Ye, Taylor P Uccello, Joseph D Murphy, Brian A Belt, Edith M Lord, Alan W Katz, David C Linehan, Scott A Gerber. less Clin Cancer Res, 2021 Dec 05; 28(1). PMID: 34862242 Free PMC article.
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Infiltrating T lymphocytes in the tumor microenvironment of small cell lung cancer: a state of knowledge review. Yamei Chen, Ying Jin, Xiao Hu, Ming Chen. J Cancer Res Clin Oncol, 2022 Jan 09; 148(4). PMID: 34997864 Review.
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Effects of Radiation on the Tumor Microenvironment. Arta M Monjazeb, Kurt A Schalper, +3 authors, Franz Villarroel-Espindola, Anthony Nguyen, Stephen L Shiao, Kristina Young. less Semin Radiat Oncol, 2020 May 10; 30(2). PMID: 32381294 Free PMC article. Review.
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Current status of immune checkpoint inhibitor therapy for advanced esophageal squamous cell carcinoma. Naoki Enomoto, Kazuhiko Yamada, +6 authors, Masayoshi Terayama, Daiki Kato, Shusuke Yagi, Hitomi Wake, Nobuyuki Takemura, Tomomichi Kiyomatsu, Norihiro Kokudo. less Glob Health Med, 2022 Jan 18; 3(6). PMID: 35036619 Free PMC article. Review.
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The power of small changes: Comprehensive analyses of microbial dysbiosis in breast cancer. Sheetal Parida, Dipali Sharma. Biochim Biophys Acta Rev Cancer, 2019 Apr 15; 1871(2). PMID: 30981803 Free PMC article. Review.
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Relationship Between Prior Radiotherapy and Checkpoint-Inhibitor Pneumonitis in Patients With Advanced Non-Small-Cell Lung Cancer. Khinh Ranh Voong, Sarah Z Hazell, +17 authors, Wei Fu, Chen Hu, Cheng Ting Lin, Kai Ding, Karthik Suresh, Jonathan Hayman, Russell K Hales, Salem Alfaifi, Kristen A Marrone, Benjamin Levy, Christine L Hann, David S Ettinger, Josephine L Feliciano, Valerie Peterson, Ronan J Kelly, Julie R Brahmer, Patrick M Forde, Jarushka Naidoo. less Clin Lung Cancer, 2019 Apr 30; 20(4). PMID: 31031204 Free PMC article.
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Combination strategies with PD-1/PD-L1 blockade: current advances and future directions. Ming Yi, Xiaoli Zheng, +3 authors, Mengke Niu, Shuangli Zhu, Hong Ge, Kongming Wu. less Mol Cancer, 2022 Jan 23; 21(1). PMID: 35062949 Free PMC article. Review.
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Double-refractory Hodgkin lymphoma: tackling relapse after brentuximab vedotin and checkpoint inhibitors. Narendranath Epperla, Mehdi Hamadani. Hematology Am Soc Hematol Educ Program, 2021 Dec 11; 2021(1). PMID: 34889401 Free PMC article. Review.
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Breast Cancer Tumor Microenvironment and Molecular Aberrations Hijack Tumoricidal Immunity. Huey-Jen Lin, Yingguang Liu, Denene Lofland, Jiayuh Lin. Cancers (Basel), 2022 Jan 22; 14(2). PMID: 35053449 Free PMC article. Review.
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Case Report: First Case of Consolidation Immunotherapy After Definitive Chemoradiotherapy in Mediastinal Lymph Node Metastatic Sarcomatoid Carcinoma. Yu Wang, Lin Yang, +7 authors, Jianyang Wang, Lin Gui, Wei Li, Zhiqiang Liu, Xiangyu Ma, Yin Yang, Luhua Wang, Nan Bi. less Front Oncol, 2022 Jan 28; 11. PMID: 35083145 Free PMC article.
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Pharmacologic inhibition of ataxia telangiectasia and Rad3-related (ATR) in the treatment of head and neck squamous cell carcinoma. Pooja Karukonda, Diana Odhiambo, Yvonne M Mowery. Mol Carcinog, 2021 Dec 30; 61(2). PMID: 34964992 Free PMC article. Review.
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Trimodality treatment in gastric and gastroesophageal junction cancers: Current approach and future perspectives. Nikolaos Charalampakis, Sergios Tsakatikas, +9 authors, Dimitrios Schizas, Stylianos Kykalos, Maria Tolia, Rodanthi Fioretzaki, Georgios Papageorgiou, Ioannis Katsaros, Ahmed Adel Fouad Abdelhakeem, Matheus Sewastjanow-Silva, Jane E Rogers, Jaffer A Ajani. less World J Gastrointest Oncol, 2022 Feb 05; 14(1). PMID: 35116110 Free PMC article. Review.
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The utilization of immunotherapy with radiation therapy in lung cancer: a narrative review. John H Heinzerling, Kathryn F Mileham, Charles B Simone. Transl Cancer Res, 2022 Feb 05; 10(5). PMID: 35116573 Free PMC article. Review.
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Narrative review of immunotherapy and radiation therapy in elderly patients. Brittney Chau, Jonnby LaGuardia, +4 authors, Caressa Hui, Linda Ye, Yan Xing, Erminia Massarelli, Arya Amini. less Transl Cancer Res, 2022 Feb 05; 10(5). PMID: 35116575 Free PMC article. Review.
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Treatment intensity in locoregionally advanced head and neck cancer: recent investigation leads to new questions. James A Bonner, Drexell H Boggs. Transl Cancer Res, 2019 Mar 01; 8(Suppl 2). PMID: 35117096 Free PMC article.
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Intracranial radiotherapy with or without immune checkpoint inhibition for brain metastases: a systematic review and meta-analysis. Qian He, Chi Zhang, +2 authors, Sheng Tang, Jiayi Li, Qinglan Ren. less Transl Cancer Res, 2020 Oct 01; 9(10). PMID: 35117204 Free PMC article.
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Radiation therapy enhances immunotherapy response in microsatellite stable colorectal and pancreatic adenocarcinoma in a phase II trial. Aparna R Parikh, Annamaria Szabolcs, +28 authors, Jill N Allen, Jeffrey W Clark, Jennifer Y Wo, Michael Raabe, Hannah Thel, David Hoyos, Arnav Mehta, Sanya Arshad, David J Lieb, Lorraine C Drapek, Lawrence S Blaszkowsky, Bruce J Giantonio, Colin D Weekes, Andrew X Zhu, Lipika Goyal, Ryan D Nipp, Jon S Dubois, Emily E Van Seventer, Bronwen E Foreman, Lauren E Matlack, Leilana Ly, Jessica A Meurer, Nir Hacohen, David P Ryan, Beow Y Yeap, Ryan B Corcoran, Benjamin D Greenbaum, David T Ting, Theodore S Hong. less Nat Cancer, 2022 Feb 06; 2(11). PMID: 35122060 Free PMC article.
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Efficacy of pembrolizumab and comprehensive CD274/PD-L1 profiles in patients previously treated with chemoradiation therapy as radical treatment in bladder cancer. Kazuki Nishimura, Kyosuke Nishio, +23 authors, Kensuke Hirosuna, Kazumasa Komura, Takuo Hayashi, Wataru Fukuokaya, Ayako Ura, Taizo Uchimoto, Ko Nakamura, Tatsuo Fukushima, Yusuke Yano, Nobushige Takahashi, Keita Nakamori, Shoko Kinoshita, Tomohisa Matsunaga, Takeshi Tsutsumi, Takuya Tsujino, Kohei Taniguchi, Tomohito Tanaka, Hirofumi Uehara, Kiyoshi Takahara, Teruo Inamoto, Yoshinobu Hirose, Takahiro Kimura, Shin Egawa, Haruhito Azuma. less J Immunother Cancer, 2022 Jan 19; 10(1). PMID: 35039462 Free PMC article.
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Thrombospondin-1 induced programmed death-ligand 1-mediated immunosuppression by activating the STAT3 pathway in osteosarcoma. Zhuochao Liu, Junxiang Wen, +3 authors, Fangqiong Hu, Jun Wang, Chuanzhen Hu, Weibin Zhang. less Cancer Sci, 2021 Dec 21; 113(2). PMID: 34927311 Free PMC article.
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Anlotinib Enhances the Antitumor Activity of High-Dose Irradiation Combined with Anti-PD-L1 by Potentiating the Tumor Immune Microenvironment in Murine Lung Cancer. Meng Yuan, Yirui Zhai, +9 authors, Yu Men, Maoyuan Zhao, Xin Sun, Zeliang Ma, Yongxing Bao, Xu Yang, Shuang Sun, Yunsong Liu, Wanting Zhang, Zhouguang Hui. less Oxid Med Cell Longev, 2022 Feb 15; 2022. PMID: 35154567 Free PMC article.
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Neoadjuvant SABR for Renal Cell Carcinoma Inferior Vena Cava Tumor Thrombus-Safety Lead-in Results of a Phase 2 Trial. Vitaly Margulis, Yuval Freifeld, +14 authors, Laurentiu M Pop, Subrata Manna, Payal Kapur, Ivan Pedrosa, Alana Christie, Osama Mohamad, Samantha Mannala, Nirmish Singla, Michael Wait, Aditya Bagrodia, Solomon L Woldu, Jeffrey Gahan, James Brugarolas, Robert Timmerman, Raquibul Hannan. less Int J Radiat Oncol Biol Phys, 2021 Feb 08; 110(4). PMID: 33549705 Free PMC article.
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Radiotherapy: Brightness and darkness in the era of immunotherapy. Danyi Zhai, Dandan An, Chao Wan, Kunyu Yang. Transl Oncol, 2022 Feb 27; 19. PMID: 35219093 Free PMC article. Review.
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Evolving management of HER2+ breast cancer brain metastases and leptomeningeal disease. Matthew N Mills, Whitney King, +6 authors, Aixa Soyano, Yolanda Pina, Brian J Czerniecki, Peter A Forsyth, Hatem Soliman, Hyo S Han, Kamran A Ahmed. less J Neurooncol, 2022 Mar 05; 157(2). PMID: 35244835 Review.
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Immunosuppressive properties of human PD-1 + , PDL-1 + and CD80 + dendritic cells from lymph nodes aspirates of lung cancer patients. Iwona Kwiecień, Elżbieta Rutkowska, +5 authors, Agata Raniszewska, Rafał Sokołowski, Joanna Bednarek, Karina Jahnz-Różyk, Piotr Rzepecki, Joanna Domagała-Kulawik. less Cancer Immunol Immunother, 2022 Mar 08;. PMID: 35254478
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cGAS/STING cross-talks with cell cycle and potentiates cancer immunotherapy. Zi-Jie Long, Jun-Dan Wang, +2 authors, Jue-Qiong Xu, Xin-Xing Lei, Quentin Liu. less Mol Ther, 2022 Feb 06; 30(3). PMID: 35121107 Free PMC article. Review.
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Anti-PD-L1 Antibody Enhances T Cell Immune Responses and Reduces Resistance of Breast Cancer Cells to Radiotherapy. Lei-Ming Guo, Gao-Feng Ding, +3 authors, Wen-Cai Xu, Hong Ge, Yue Jiang, Yu-Fei Lu. less Oxid Med Cell Longev, 2022 Mar 18; 2022. PMID: 35295718 Free PMC article.
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Novel imaging biomarkers predict outcomes in stage III unresectable non-small cell lung cancer treated with chemoradiation and durvalumab. Khalid Jazieh, Mohammadhadi Khorrami, +10 authors, Anas Saad, Mohamed Gad, Amit Gupta, Pradnya Patil, Vidya Sankar Viswanathan, Prabhakar Rajiah, Charles J Nock, Michael Gilkey, Pingfu Fu, Nathan A Pennell, Anant Madabhushi. less J Immunother Cancer, 2022 Mar 09; 10(3). PMID: 35256515 Free PMC article.
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The Treatment Landscape of Advanced Hepatocellular Carcinoma. Kit Man Wong, Gentry G King, William P Harris. Curr Oncol Rep, 2022 Mar 30; 24(7). PMID: 35347594 Review.
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Carbon ion radiotherapy triggers immunogenic cell death and sensitizes melanoma to anti-PD-1 therapy in mice. Heng Zhou, Chen Tu, +9 authors, Pengfei Yang, Jin Li, Oliver Kepp, Haining Li, Liying Zhang, Lixin Zhang, Yang Zhao, Tianyi Zhang, Chengyan Sheng, Jufang Wang. less Oncoimmunology, 2022 Apr 01; 11(1). PMID: 35355680 Free PMC article.
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HLA class I antigen processing machinery defects in antitumor immunity and immunotherapy. Luke Maggs, Ananthan Sadagopan, Ali Sanjari Moghaddam, Soldano Ferrone. Trends Cancer, 2021 Sep 08; 7(12). PMID: 34489208 Free PMC article. Review.
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Functional Diversities of Regulatory T Cells in the Context of Cancer Immunotherapy. Ran Gao, Guo-Ping Shi, Jing Wang. Front Immunol, 2022 Apr 05; 13. PMID: 35371055 Free PMC article. Review.
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A Patient-Level Data Meta-analysis of the Abscopal Effect. Steven J Hatten, Eric J Lehrer, +7 authors, Jenn Liao, Congzhou M Sha, Daniel M Trifiletti, Shankar Siva, Sean M McBride, David Palma, Sheldon L Holder, Nicholas G Zaorsky. less Adv Radiat Oncol, 2022 Apr 05; 7(3). PMID: 35372719 Free PMC article. Review.
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Immune suppressive microenvironment in brain metastatic non-small cell lung cancer: comprehensive immune microenvironment profiling of brain metastases versus paired primary lung tumors (GASTO 1060). Meichen Li, Xue Hou, +9 authors, Ke Sai, Lihong Wu, Jing Chen, Baishen Zhang, Na Wang, Lijia Wu, Hongbo Zheng, Jiao Zhang, Yonggao Mou, Likun Chen. less Oncoimmunology, 2022 Apr 12; 11(1). PMID: 35402080 Free PMC article.
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Immunomodulatory effect of splenectomy in lung cancer mouse xenograft models receiving radiation therapy. Yeeun Kim, Changhoon Choi, +4 authors, Jee Hyun Park, Won-Gyun Ahn, Sung-Won Shin, Shin-Yeong Kim, Jae Myoung Noh. less Radiat Oncol J, 2022 Apr 05; 40(1). PMID: 35368201 Free PMC article.
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Multimodality Treatment including Surgery Related to the Type of N2 Involvement in Locally Advanced Non-Small Cell Lung Cancer. Toon Allaeys, Lawek Berzenji, +5 authors, Patrick Lauwers, Suresh Krishan Yogeswaran, Jeroen M H Hendriks, Charlotte Billiet, Charlotte De Bondt, Paul E Van Schil. less Cancers (Basel), 2022 Apr 13; 14(7). PMID: 35406428 Free PMC article. Review.
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Rationale and design of a prospective, multicenter, phase II clinical trial of safety and efficacy evaluation of long course neoadjuvant chemoradiotherapy plus tislelizumab followed by total mesorectal excision for locally advanced rectal cancer (NCRT-PD1-LARC trial). Zhengyang Yang, Xiao Zhang, +14 authors, Jie Zhang, Jiale Gao, Zhigang Bai, Wei Deng, Guangyong Chen, Yongbo An, Yishan Liu, Qi Wei, Jiagang Han, Ang Li, Gang Liu, Yi Sun, Dalu Kong, Hongwei Yao, Zhongtao Zhang. less BMC Cancer, 2022 Apr 29; 22(1). PMID: 35477432 Free PMC article.
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Combining Radiotherapy and Immunotherapy in Metastatic Breast Cancer: Current Status and Future Directions. Steven David, Jennifer Tan, +3 authors, Shankar Siva, Lama Karroum, Peter Savas, Sherene Loi. less Biomedicines, 2022 Apr 24; 10(4). PMID: 35453571 Free PMC article. Review.
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Consolidation treatments after chemoradiotherapy in patients with locally advanced inoperable non-small cell lung cancer: a systematic review and network meta-analysis protocol. Ye Zhao, Haiming Feng, +6 authors, Jinhui Tian, Bin Li, Cheng Wang, Long Ge, Jian Kai Wang, Kehu Yang, Qin Yu. less BMJ Open, 2022 Apr 14; 12(4). PMID: 35414564 Free PMC article.
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Mathematical modeling of radiotherapy and its impact on tumor interactions with the immune system. Rebecca Anne Bekker, Sungjune Kim, Shari Pilon-Thomas, Heiko Enderling. Neoplasia, 2022 Apr 22; 28. PMID: 35447601 Free PMC article. Review.
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Current status and advances of immunotherapy in nasopharyngeal carcinoma. Jian-Ying Xu, Xiao-Li Wei, Yi-Qin Wang, Feng-Hua Wang. Ther Adv Med Oncol, 2022 May 14; 14. PMID: 35547095 Free PMC article. Review.
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A review of mechanisms of resistance to immune checkpoint inhibitors and potential strategies for therapy. Yu Fujiwara, Arjun Mittra, Abdul Rafeh Naqash, Naoko Takebe. Cancer Drug Resist, 2020 Jun 18; 3(3). PMID: 35582437 Free PMC article. Review.
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Mechanism of resistance to immune checkpoint inhibitors. Manu R Pandey, Marc S Ernstoff. Cancer Drug Resist, 2019 Jun 19; 2(2). PMID: 35582715 Free PMC article. Review.
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Adaptive immune resistance at the tumour site: mechanisms and therapeutic opportunities. Tae Kon Kim, Esten N Vandsemb, Roy S Herbst, Lieping Chen. Nat Rev Drug Discov, 2022 Jun 15;. PMID: 35701637 Review.
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