Review
. 2014 Jan; 8(2):149-54.
doi: 10.1159/000350774.

A Brief Overview of the WHO Classification of Breast Tumors, 4th Edition, Focusing on Issues and Updates from the 3rd Edition

Hans-Peter Sinn 1 Hans Kreipe 2 
Affiliations
  • PMID: 24415964
  •     29 References
  •     80 citations

Abstract

The WHO Classification of Tumors of the Breast, 4th edition, is an update to the 3rd edition that was published in 2003, and covers all neoplastic and preneoplastic lesions of the breast. Changes to the 4th edition include new aspects and changes to the terminology that reflect our present-day knowledge of these lesions. Definitions for histopathological diagnosis are complemented by a description of clinical features, epidemiology, macroscopy, genetics, and prognostic and predictive features. In this review of the WHO classification, we have focused on invasive carcinomas, precursor lesions, and some benign epithelial proliferations.

Keywords: Breast Cancer; Diagnostic criteria; Pathology; WHO classification.

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Breast Cancer (Auckl), 2021 May 18; 15. PMID: 33994789    Free PMC article.
Review.
Metabolic comorbidities and the association with risks of recurrent metastatic disease in breast cancer survivors.
Sumadi Lukman Anwar, Roby Cahyono, +5 authors, Teguh Aryandono.
BMC Cancer, 2021 May 24; 21(1). PMID: 34022845    Free PMC article.
Loss of Mammographic Tissue Homeostasis in Invasive Lobular and Ductal Breast Carcinomas vs. Benign Lesions.
Evgeniya Gerasimova-Chechkina, Brian C Toner, +5 authors, Andre Khalil.
Front Physiol, 2021 Jun 01; 12. PMID: 34054577    Free PMC article.