Journal Article
. 2014 Apr; 106(5):.
doi: 10.1093/jnci/dju055.

US incidence of breast cancer subtypes defined by joint hormone receptor and HER2 status

Nadia Howlader 1 Sean F Altekruse 2 Christopher I Li 2 Vivien W Chen 2 Christina A Clarke 2 Lynn A G Ries 2 Kathleen A Cronin 2 
  • PMID: 24777111
  •     28 References
  •     359 citations


Background: In 2010, Surveillance, Epidemiology, and End Results (SEER) registries began collecting human epidermal growth factor 2 (HER2) receptor status for breast cancer cases.

Methods: Breast cancer subtypes defined by joint hormone receptor (HR; estrogen receptor [ER] and progesterone receptor [PR]) and HER2 status were assessed across the 28% of the US population that is covered by SEER registries. Age-specific incidence rates by subtype were calculated for non-Hispanic (NH) white, NH black, NH Asian Pacific Islander (API), and Hispanic women. Joint HR/HER2 status distributions by age, race/ethnicity, county-level poverty, registry, stage, Bloom-Richardson grade, tumor size, and nodal status were evaluated using multivariable adjusted polytomous logistic regression. All statistical tests were two-sided.

Results: Among case patients with known HR/HER2 status, 36810 (72.7%) were found to be HR(+)/HER2(-), 6193 (12.2%) were triple-negative (HR(-)/HER2(-)), 5240 (10.3%) were HR(+)/HER2(+), and 2328 (4.6%) were HR(-)/HER2(+); 6912 (12%) had unknown HR/HER2 status. NH white women had the highest incidence rate of the HR(+)/HER2(-) subtype, and NH black women had the highest rate of the triple-negative subtype. Compared with women with the HR(+)/HER2(-) subtype, triple-negative patients were more likely to be NH black and Hispanic; HR(+)/HER2(+) patients were more likely to be NH API; and HR(-)/HER2(+) patients were more likely to be NH black, NH API, and Hispanic. Patients with triple-negative, HR(+)/HER2(+), and HR(-)/HER2(+) breast cancer were 10% to 30% less likely to be diagnosed at older ages compared with HR(+)/HER2(-) patients and 6.4-fold to 20.0-fold more likely to present with high-grade disease.

Conclusions: In the future, SEER data can be used to monitor clinical outcomes in women diagnosed with different molecular subtypes of breast cancer for a large portion (approximately 28%) of the US population.

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Breast cancer in Asian Americans in California, 1988-2013: increasing incidence trends and recent data on breast cancer subtypes.
Scarlett Lin Gomez, Julie Von Behren, +5 authors, Sally L Glaser.
Breast Cancer Res Treat, 2017 Apr 04; 164(1). PMID: 28365834    Free PMC article.
Estrogen receptors in breast and bone: from virtue of remodeling to vileness of metastasis.
I Bado, Z Gugala, S A W Fuqua, X H-F Zhang.
Oncogene, 2017 Apr 04; 36(32). PMID: 28368409    Free PMC article.
Using the 21-gene assay from core needle biopsies to choose neoadjuvant therapy for breast cancer: A multicenter trial.
Harry D Bear, Wen Wan, +8 authors, Amy P Sing.
J Surg Oncol, 2017 Apr 14; 115(8). PMID: 28407247    Free PMC article.
Safety Evaluation of Trastuzumab Emtansine in Japanese Patients with HER2-Positive Advanced Breast Cancer.
Junichiro Watanabe, Yoshinori Ito, +8 authors, Takahiro Nakayama.
In Vivo, 2017 Apr 26; 31(3). PMID: 28438884    Free PMC article.
Protecting Confidentiality in Cancer Registry Data With Geographic Identifiers.
Mandi Yu, Jerome Phillip Reiter, +3 authors, Eric J Rocky Feuer.
Am J Epidemiol, 2017 Apr 30; 186(1). PMID: 28453646    Free PMC article.
Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas.
Dezheng Huo, Hai Hu, +17 authors, Olufunmilayo I Olopade.
JAMA Oncol, 2017 May 05; 3(12). PMID: 28472234    Free PMC article.
Highly Cited.
Direct estrogen receptor (ER) / HER family crosstalk mediating sensitivity to lumretuzumab and pertuzumab in ER+ breast cancer.
Denis Collins, Wolfgang Jacob, +7 authors, Birgit Bossenmaier.
PLoS One, 2017 May 12; 12(5). PMID: 28493933    Free PMC article.
Spironolactone ameliorates the cardiovascular toxicity induced by concomitant trastuzumab and thoracic radiotherapy.
Guler Yavas, Esin Celik, +2 authors, Rengin Elsurer Afsar.
Rep Pract Oncol Radiother, 2017 May 17; 22(4). PMID: 28507459    Free PMC article.
Breast Cancer Disparities at Home and Abroad: A Review of the Challenges and Opportunities for System-Level Change.
Katherine E Reeder-Hayes, Benjamin O Anderson.
Clin Cancer Res, 2017 Jun 03; 23(11). PMID: 28572260    Free PMC article.
Active smoking and survival following breast cancer among African American and non-African American women in the Carolina Breast Cancer Study.
Humberto Parada, Xuezheng Sun, +3 authors, Kathleen Conway.
Cancer Causes Control, 2017 Jul 12; 28(9). PMID: 28695396    Free PMC article.
Contribution of clinical and socioeconomic factors to differences in breast cancer subtype and mortality between Hispanic and non-Hispanic white women.
María Elena Martínez, Scarlett L Gomez, +8 authors, Christopher Li.
Breast Cancer Res Treat, 2017 Jul 13; 166(1). PMID: 28698973    Free PMC article.
Hormone receptor status of a first primary breast cancer predicts contralateral breast cancer risk in the WECARE study population.
Anne S Reiner, Charles F Lynch, +16 authors, WECARE Study Collaborative Group.
Breast Cancer Res, 2017 Jul 21; 19(1). PMID: 28724391    Free PMC article.
Joint relative risks for estrogen receptor-positive breast cancer from a clinical model, polygenic risk score, and sex hormones.
Yiwey Shieh, Donglei Hu, +7 authors, Steven R Cummings.
Breast Cancer Res Treat, 2017 Aug 10; 166(2). PMID: 28791495    Free PMC article.
Estrogen receptor (ESR1) mutation in bone metastases from breast cancer.
Stephan Bartels, Matthias Christgen, +4 authors, Hans Kreipe.
Mod Pathol, 2017 Aug 12; 31(1). PMID: 28799536
Regional Variability in Percentage of Breast Cancers Reported as Positive for HER2 in California: Implications of Patient Demographics on Laboratory Benchmarks.
Chieh-Yu Lin, Eugene E Carneal, +5 authors, Kimberly H Allison.
Am J Clin Pathol, 2017 Aug 20; 148(3). PMID: 28821197    Free PMC article.
Pubertal growth and adult height in relation to breast cancer risk in African American women.
Kimberly A Bertrand, Hanna Gerlovin, Traci N Bethea, Julie R Palmer.
Int J Cancer, 2017 Aug 29; 141(12). PMID: 28845597    Free PMC article.
Racial Differences in PAM50 Subtypes in the Carolina Breast Cancer Study.
Melissa A Troester, Xuezheng Sun, +16 authors, Charles M Perou.
J Natl Cancer Inst, 2017 Sep 02; 110(2). PMID: 28859290    Free PMC article.
Long non-coding RNA00544 serves as a potential novel predictive and prognostic marker for HR+ HER2- subtype breast cancer.
Lei Liu, Yayun Chi, +5 authors, Jiong Wu.
Sci Rep, 2017 Sep 30; 7(1). PMID: 28959047    Free PMC article.
Breast Cancer in Latinas: A Focus on Intrinsic Subtypes Distribution.
Silvia J Serrano-Gómez, Laura Fejerman, Jovanny Zabaleta.
Cancer Epidemiol Biomarkers Prev, 2017 Oct 22; 27(1). PMID: 29054978    Free PMC article.
Ribociclib with letrozole vs letrozole alone in elderly patients with hormone receptor-positive, HER2-negative breast cancer in the randomized MONALEESA-2 trial.
Gabe S Sonke, Lowell L Hart, +16 authors, Howard A Burris.
Breast Cancer Res Treat, 2017 Oct 24; 167(3). PMID: 29058175    Free PMC article.
Propensity-score-matched evaluation of the incidence of radiation pneumonitis and secondary cancer risk for breast cancer patients treated with IMRT/VMAT.
Pei-Ju Chao, Hsiao-Fei Lee, +5 authors, Tsair-Fwu Lee.
Sci Rep, 2017 Oct 25; 7(1). PMID: 29062118    Free PMC article.
Neoadjuvant everolimus plus letrozole versus fluorouracil, epirubicin and cyclophosphamide for ER-positive, HER2-negative breast cancer: study protocol for a randomized pilot trial.
Wei Wu, Heran Deng, +4 authors, Jieqiong Liu.
Trials, 2017 Oct 27; 18(1). PMID: 29070044    Free PMC article.
Electronic Health Record Phenotypes for Precision Medicine: Perspectives and Caveats From Treatment of Breast Cancer at a Single Institution.
Matthew K Breitenstein, Hongfang Liu, +2 authors, Rui Zhang.
Clin Transl Sci, 2017 Oct 31; 11(1). PMID: 29084368    Free PMC article.
Release of HER2 repression of trefoil factor 3 (TFF3) expression mediates trastuzumab resistance in HER2+/ER+ mammary carcinoma.
Qing-Yun Chong, Ming-Liang You, +9 authors, Peter E Lobie.
Oncotarget, 2017 Nov 02; 8(43). PMID: 29088778    Free PMC article.
Leptin regulation of the p53-HIF1α/PKM2-aromatase axis in breast adipose stromal cells: a novel mechanism for the obesity-breast cancer link.
H Zahid, K Subbaramaiah, +8 authors, K A Brown.
Int J Obes (Lond), 2017 Nov 07; 42(4). PMID: 29104286    Free PMC article.
Polyphenols as Promising Drugs against Main Breast Cancer Signatures.
María Losada-Echeberría, María Herranz-López, Vicente Micol, Enrique Barrajón-Catalán.
Antioxidants (Basel), 2017 Nov 08; 6(4). PMID: 29112149    Free PMC article.
Novel Predictors of Breast Cancer Survival Derived from miRNA Activity Analysis.
Vasily N Aushev, Eunjee Lee, +11 authors, Jia Chen.
Clin Cancer Res, 2017 Nov 16; 24(3). PMID: 29138345    Free PMC article.
3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry.
D O Velez, B Tsui, +4 authors, S I Fraley.
Nat Commun, 2017 Nov 23; 8(1). PMID: 29162797    Free PMC article.
Genetic and clinical characteristics in Japanese hereditary breast and ovarian cancer: first report after establishment of HBOC registration system in Japan.
Masami Arai, Shiro Yokoyama, +12 authors, Seigo Nakamura.
J Hum Genet, 2017 Nov 28; 63(4). PMID: 29176636
Arachidonic Acid Metabolite as a Novel Therapeutic Target in Breast Cancer Metastasis.
Thaiz F Borin, Kartik Angara, +2 authors, Ali S Arbab.
Int J Mol Sci, 2018 Jan 03; 18(12). PMID: 29292756    Free PMC article.
Subgroup analysis of patients with HER2-negative metastatic breast cancer in the second-line setting from a phase 3, open-label, randomized study of eribulin mesilate versus capecitabine.
Xavier Pivot, Seock Ah Im, Matthew Guo, Frederik Marmé.
Breast Cancer, 2018 Jan 06; 25(3). PMID: 29302858    Free PMC article.
Association of Screening and Treatment With Breast Cancer Mortality by Molecular Subtype in US Women, 2000-2012.
Sylvia K Plevritis, Diego Munoz, +20 authors, Jeanne S Mandelblatt.
JAMA, 2018 Jan 11; 319(2). PMID: 29318276    Free PMC article.
Highly Cited.
Reproductive history, breast-feeding and risk of triple negative breast cancer: The Breast Cancer Etiology in Minorities (BEM) study.
Esther M John, Lisa M Hines, +6 authors, Anna H Wu.
Int J Cancer, 2018 Jan 14; 142(11). PMID: 29330856    Free PMC article.
Black-White Disparities in Breast Cancer Subtype: The Intersection of Socially Patterned Stress and Genetic Expression.
Erin Linnenbringer, Sarah Gehlert, Arline T Geronimus.
AIMS Public Health, 2018 Jan 16; 4(5). PMID: 29333472    Free PMC article.
Metabolomics Reveals that Dietary Xenoestrogens Alter Cellular Metabolism Induced by Palbociclib/Letrozole Combination Cancer Therapy.
Benedikt Warth, Philipp Raffeiner, +7 authors, Gary Siuzdak.
Cell Chem Biol, 2018 Jan 18; 25(3). PMID: 29337187    Free PMC article.
Harnessing a Different Dependency: How to Identify and Target Androgen Receptor-Positive Versus Quadruple-Negative Breast Cancer.
Jessica L Christenson, Jane B Trepel, +5 authors, Jennifer K Richer.
Horm Cancer, 2018 Jan 18; 9(2). PMID: 29340907    Free PMC article.
Association of urinary and plasma DNA in early breast cancer patients and its links to disease relapse.
Z Liu, W Liu.
Clin Transl Oncol, 2018 Feb 03; 20(8). PMID: 29392540
Frequency of breast cancer subtypes among African American women in the AMBER consortium.
Emma H Allott, Joseph Geradts, +24 authors, Melissa A Troester.
Breast Cancer Res, 2018 Feb 08; 20(1). PMID: 29409530    Free PMC article.
Trends in molecular subtypes of breast cancer: description of incidence rates between 2007 and 2012 from three French registries.
Marion Cortet, Aurélie Bertaut, +4 authors, Patrick Arveux.
BMC Cancer, 2018 Feb 09; 18(1). PMID: 29415671    Free PMC article.
Brain metastasis in gastroesophageal adenocarcinoma and HER2 status.
Dror Limon, Omer Gal, +10 authors, Shlomit Yust-Katz.
J Neurooncol, 2018 Feb 13; 138(2). PMID: 29429124
Differences in breast cancer incidence among young women aged 20-49 years by stage and tumor characteristics, age, race, and ethnicity, 2004-2013.
Meredith L Shoemaker, Mary C White, +2 authors, Isabelle Romieu.
Breast Cancer Res Treat, 2018 Feb 16; 169(3). PMID: 29445940    Free PMC article.
Serum insulin-like growth factor (IGF)-I and IGF binding protein-3 in relation to terminal duct lobular unit involution of the normal breast in Caucasian and African American women: The Susan G. Komen Tissue Bank.
Hannah Oh, Ruth M Pfeiffer, +8 authors, Jonine D Figueroa.
Int J Cancer, 2018 Feb 24; 143(3). PMID: 29473153    Free PMC article.
The Difference in Prognostic Outcomes Between De Novo Stage IV and Recurrent Metastatic Patients with Hormone Receptor-positive, HER2-negative Breast Cancer.
Jun Yamamura, Shunji Kamigaki, +2 authors, Yoshifumi Komoike.
In Vivo, 2018 Feb 25; 32(2). PMID: 29475920    Free PMC article.
Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation.
Mustapha Abubakar, Jenny Chang-Claude, +34 authors, Montserrat Garcia-Closas.
Int J Cancer, 2018 Mar 02; 143(4). PMID: 29492969    Free PMC article.
Breast cancer-specific survival by age: Worse outcomes for the oldest patients.
Rachel A Freedman, Nancy L Keating, +5 authors, William T Barry.
Cancer, 2018 Mar 03; 124(10). PMID: 29499074    Free PMC article.
Clinical and economic burden associated with stage III to IV triple-negative breast cancer: A SEER-Medicare historical cohort study in elderly women in the United States.
Kendra L Schwartz, Michael S Simon, +7 authors, Ruben G W Quek.
Cancer, 2018 Mar 06; 124(10). PMID: 29505670    Free PMC article.
Candidate gene DNA methylation associations with breast cancer characteristics and tumor progression.
Jacob K Kresovich, Peter H Gann, +3 authors, Garth H Rauscher.
Epigenomics, 2018 Mar 13; 10(4). PMID: 29528252    Free PMC article.
Aromatase inhibitors are associated with a higher fracture risk than tamoxifen: a systematic review and meta-analysis.
Olivia L Tseng, John J Spinelli, +3 authors, Martin G Dawes.
Ther Adv Musculoskelet Dis, 2018 Apr 06; 10(4). PMID: 29619093    Free PMC article.
Obesity and Breast Cancer: A Complex Relationship.
Victoria M Gershuni, Rexford S Ahima, Julia Tchou.
Curr Surg Rep, 2016 Apr 01; 4. PMID: 29623246    Free PMC article.
Calmodulin antagonist enhances DR5-mediated apoptotic signaling in TRA-8 resistant triple negative breast cancer cells.
Romone M Fancy, Harrison Kim, +3 authors, Yuhua Song.
J Cell Biochem, 2018 Apr 18; 119(7). PMID: 29663486    Free PMC article.
Current Therapies for Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer Patients.
Alexey A Larionov.
Front Oncol, 2018 Apr 20; 8. PMID: 29670855    Free PMC article.
Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer.
Nicole Blanchette-Farra, Daniel Kita, +6 authors, Suzy V Torti.
Oncogene, 2018 Apr 27; 37(29). PMID: 29695834    Free PMC article.
Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer.
Joseph A Sparano, Robert J Gray, +27 authors, George W Sledge.
N Engl J Med, 2018 Jun 05; 379(2). PMID: 29860917    Free PMC article.
Highly Cited.
BRCA1/2 testing: therapeutic implications for breast cancer management.
Nadine M Tung, Judy E Garber.
Br J Cancer, 2018 Jun 06; 119(2). PMID: 29867226    Free PMC article.
Overcoming endocrine resistance in hormone receptor-positive breast cancer.
A AlFakeeh, C Brezden-Masley.
Curr Oncol, 2018 Jun 19; 25(Suppl 1). PMID: 29910644    Free PMC article.
Endocrine therapy for breast cancer in the primary care setting.
A Awan, K Esfahani.
Curr Oncol, 2018 Aug 17; 25(4). PMID: 30111969    Free PMC article.
Adherence to guidelines in requesting Oncotype DX in a publicly funded health care system.
S Martel, M Lambertini, +2 authors, C Prady.
Curr Oncol, 2018 Aug 17; 25(4). PMID: 30111977    Free PMC article.
Molecular profiling of hormone receptor-positive, HER2-negative breast cancers from patients treated with neoadjuvant endocrine therapy in the CARMINA 02 trial (UCBG-0609).
Xu Liang, Adrien Briaux, +12 authors, Céline Callens.
J Hematol Oncol, 2018 Oct 12; 11(1). PMID: 30305115    Free PMC article.
SIRT1 and Estrogen Signaling Cooperation for Breast Cancer Onset and Progression.
Sergio Liarte, José Luis Alonso-Romero, Francisco José Nicolás.
Front Endocrinol (Lausanne), 2018 Oct 16; 9. PMID: 30319540    Free PMC article.
Menopausal Hormone Therapy use and breast cancer risk by receptor subtypes: Results from the New South Wales Cancer Lifestyle and EvaluAtion of Risk (CLEAR) study.
Usha Salagame, Emily Banks, +2 authors, Karen Canfell.
PLoS One, 2018 Nov 08; 13(11). PMID: 30403669    Free PMC article.
A paradigm shift for the treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer: a review of CDK inhibitors.
Mariane Teodoro Fernandes, Jacob J Adashek, +5 authors, Pedro Nazareth Aguiar.
Drugs Context, 2018 Nov 13; 7. PMID: 30416529    Free PMC article.
Disparities in Breast Cancer Survival by Socioeconomic Status Despite Medicare and Medicaid Insurance.
Jeffrey H Silber, Paul R Rosenbaum, +8 authors, Kevin R Fox.
Milbank Q, 2018 Dec 12; 96(4). PMID: 30537364    Free PMC article.
Crumbs protein homolog 3 (CRB3) expression is associated with oestrogen and progesterone receptor positivity in breast cancer.
Pingping Li, Can Zhou, +4 authors, Peijun Liu.
Clin Exp Pharmacol Physiol, 2019 May 16; 46(9). PMID: 31087799    Free PMC article.
From latency to overt bone metastasis in breast cancer: potential for treatment and prevention.
Fernando Salvador, Alicia Llorente, Roger R Gomis.
J Pathol, 2019 May 17; 249(1). PMID: 31095738    Free PMC article.
Effects of SLCO1B1 polymorphisms on plasma estrogen concentrations in women with breast cancer receiving aromatase inhibitors exemestane and letrozole.
Jacqueline M Dempsey, Kelley M Kidwell, +9 authors, Daniel L Hertz.
Pharmacogenomics, 2019 Jun 14; 20(8). PMID: 31190621    Free PMC article.
MCF-7 as a Model for Functional Analysis of Breast Cancer Risk Variants.
Alix Booms, Gerhard A Coetzee, Steven E Pierce.
Cancer Epidemiol Biomarkers Prev, 2019 Jul 12; 28(10). PMID: 31292138    Free PMC article.
Race and delays in breast cancer treatment across the care continuum in the Carolina Breast Cancer Study.
Katherine E Reeder-Hayes, Sophie E Mayer, +5 authors, Melissa A Troester.
Cancer, 2019 Aug 10; 125(22). PMID: 31398265    Free PMC article.
Should Tumor Infiltrating Lymphocytes, Androgen Receptor, and FOXA1 Expression Predict the Clinical Outcome in Triple Negative Breast Cancer Patients?
Anita Mangia, Concetta Saponaro, +7 authors, Nicola Silvestris.
Cancers (Basel), 2019 Sep 22; 11(9). PMID: 31540486    Free PMC article.
Hybrid 18F-FDG-PET/MRI Measurement of Standardized Uptake Value Coupled with Yin Yang 1 Signature in Metastatic Breast Cancer. A Preliminary Study.
Concetta Schiano, Monica Franzese, +5 authors, Claudio Napoli.
Cancers (Basel), 2019 Sep 29; 11(10). PMID: 31561604    Free PMC article.
Obesity and survival among a cohort of breast cancer patients is partially mediated by tumor characteristics.
Cindy K Blair, Charles L Wiggins, +5 authors, Deirdre A Hill.
NPJ Breast Cancer, 2019 Oct 12; 5. PMID: 31602394    Free PMC article.
Inhibition of miRNA-34a promotes triple negative cancer cell proliferation by promoting glucose uptake.
Zhen Li, Xiaoxuan Gong, +5 authors, Jinhai Tang.
Exp Ther Med, 2019 Oct 17; 18(5). PMID: 31616515    Free PMC article.
Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis.
Inês Godet, Yu Jung Shin, +3 authors, Daniele M Gilkes.
Nat Commun, 2019 Oct 28; 10(1). PMID: 31649238    Free PMC article.
Greater absolute risk for all subtypes of breast cancer in the US than Malaysia.
Hisani N Horne, C R Beena Devi, +6 authors, Xiaohong R Yang.
Breast Cancer Res Treat, 2014 Dec 30; 149(1). PMID: 25537643    Free PMC article.
Subtypes of Breast Cancer in Lao P.D.R.: A Study in a Limited-Resource Setting
Thitsamay Luangxay, Siriphone Virachith, +8 authors, Motoji Sawabe.
Asian Pac J Cancer Prev, 2019 Feb 26; 20(2). PMID: 30806064    Free PMC article.
Luminal B is the Most Common Intrinsic Molecular Subtypes of Invasive Ductal Breast Carcinoma Patients in East Kalimantan, Indonesia.
Swandari Paramita, Eko Nugroho Raharjo, +2 authors, Nur Ahlina Hanifah.
Asian Pac J Cancer Prev, 2019 Aug 28; 20(8). PMID: 31450891    Free PMC article.
Contrasting Epidemiology and Clinicopathology of Female Breast Cancer in Asians vs the US Population.
Ching-Hung Lin, Yoon Sim Yap, +15 authors, Asian Breast Cancer Cooperative Group.
J Natl Cancer Inst, 2019 May 17; 111(12). PMID: 31093668    Free PMC article.
Is Breast Cancer in Asian and Asian American Women a Different Disease?
Scarlett Lin Gomez, Song Yao, Lawrence H Kushi, Allison W Kurian.
J Natl Cancer Inst, 2019 May 17; 111(12). PMID: 31093671    Free PMC article.
Prognostic factors and survival outcomes according to tumor subtype in patients with breast cancer lung metastases.
Siying Chen, Jin Yang, +3 authors, Jun Lyu.
PeerJ, 2019 Dec 25; 7. PMID: 31871847    Free PMC article.
The evaluation of the distribution of CD133, CXCR1 and the tumor associated macrophages in different molecular subtypes of breast cancer.
Can Ilgın, Erdem Çomut, +3 authors, Sevda Fatma Müftüoğlu.
Histol Histopathol, 2019 Jun 30; 35(1). PMID: 31250425
T1-2N1M0 triple-negative breast cancer patients from the SEER database showed potential benefit from post-mastectomy radiotherapy.
Xueying Wang, Yingying Xu, +6 authors, Liang Zong.
Oncol Lett, 2020 Jan 04; 19(1). PMID: 31897189    Free PMC article.
A phase I/II study of epertinib plus trastuzumab with or without chemotherapy in patients with HER2-positive metastatic breast cancer.
Iain R Macpherson, Pavlina Spiliopoulou, +11 authors, James Spicer.
Breast Cancer Res, 2020 Jan 02; 22(1). PMID: 31892325    Free PMC article.
Downregulation of CXXC Finger Protein 4 Leads to a Tamoxifen-resistant Phenotype in Breast Cancer Cells Through Activation of the Wnt/β-catenin Pathway.
Yijie Fu, Zhu Wang, +4 authors, Hong Zheng.
Transl Oncol, 2020 Jan 09; 13(2). PMID: 31911277    Free PMC article.
Clinicopathologic characteristics of HER2-positive pure mucinous breast carcinoma: a systematic investigation into an unusual tumor.
Ya-Ni Wei, Shan Liu, +3 authors, Bing Wei.
Int J Clin Exp Pathol, 2020 Jan 15; 12(5). PMID: 31933985    Free PMC article.
Demand for Precision Medicine: A Discrete-Choice Experiment and External Validation Study.
Dean A Regier, David L Veenstra, Anirban Basu, Josh J Carlson.
Pharmacoeconomics, 2019 Sep 07; 38(1). PMID: 31489595
Potential Life-Years Lost: The Impact of the Cancer Drug Regulatory and Funding Process in Canada.
Joanna Gotfrit, John J W Shin, +2 authors, Paul Wheatley-Price.
Oncologist, 2019 Sep 12; 25(1). PMID: 31506392    Free PMC article.
H2Mab-77 is a Sensitive and Specific Anti-HER2 Monoclonal Antibody Against Breast Cancer.
Shunsuke Itai, Yuki Fujii, +10 authors, Yukinari Kato.
Monoclon Antib Immunodiagn Immunother, 2017 Jul 13; 36(4). PMID: 28700270    Free PMC article.
Systemic treatment of hormone receptor positive, human epidermal growth factor 2 negative metastatic breast cancer: retrospective analysis from Leeds Cancer Centre.
Chris Twelves, Sue Cheeseman, +9 authors, Tim Perren.
BMC Cancer, 2020 Jan 23; 20(1). PMID: 31964373    Free PMC article.
Comparison of Clinico-Pathological Presentations of Triple-Negative versus Triple-Positive and HER2 Iraqi Breast Cancer Patients.
Nada A S Alwan, Furat N Tawfeeq.
Open Access Maced J Med Sci, 2020 Feb 06; 7(21). PMID: 32010372    Free PMC article.
Risk factors for estrogen receptor positive ductal carcinoma in situ of the breast in African American women.
Kimberly A Bertrand, Traci N Bethea, +5 authors, Julie R Palmer.
Breast, 2019 Dec 02; 49. PMID: 31786415    Free PMC article.
De Novo Versus Recurrent HER2-Positive Metastatic Breast Cancer: Patient Characteristics, Treatment, and Survival from the SystHERs Registry.
Debu Tripathy, Adam Brufsky, +11 authors, Sara A Hurvitz.
Oncologist, 2020 Feb 12; 25(2). PMID: 32043771    Free PMC article.
17β-Hydroxysteroid dehydrogenase 1:2 and breast cancer recurrence: a Danish population-based study.
Lindsay J Collin, Sinna P Ulrichsen, +13 authors, Timothy L Lash.
Acta Oncol, 2019 Nov 02; 59(3). PMID: 31671023    Free PMC article.
Disadvantaged neighborhoods and racial disparity in breast cancer outcomes: the biological link.
Geetanjali Saini, Angela Ogden, +3 authors, Ritu Aneja.
Cancer Causes Control, 2019 May 22; 30(7). PMID: 31111277    Free PMC article.
High prevalence of the MLH1 V384D germline mutation in patients with HER2-positive luminal B breast cancer.
Seung Eun Lee, Hye Seung Lee, +4 authors, Wan-Seop Kim.
Sci Rep, 2019 Jul 31; 9(1). PMID: 31358837    Free PMC article.
Racial Differences in 21-Gene Recurrence Scores Among Patients With Hormone Receptor-Positive, Node-Negative Breast Cancer.
Andreana N Holowatyj, Michele L Cote, +5 authors, Kristen S Purrington.
J Clin Oncol, 2018 Jan 18; 36(7). PMID: 29341832    Free PMC article.
Fulvestrant-Based Combination Therapy for Second-Line Treatment of Hormone Receptor-Positive Advanced Breast Cancer.
Sarah Sammons, Noah S Kornblum, Kimberly L Blackwell.
Target Oncol, 2018 Aug 24; 14(1). PMID: 30136059    Free PMC article.
Ribociclib with an Aromatase Inhibitor for Previously Untreated, HR-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.
Nasuh C Büyükkaramikli, Saskia de Groot, +6 authors, Maiwenn J Al.
Pharmacoeconomics, 2018 Sep 09; 37(2). PMID: 30194622    Free PMC article.
Intraductal patient-derived xenografts of estrogen receptor α-positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions.
Maryse Fiche, Valentina Scabia, +9 authors, Cathrin Brisken.
J Pathol, 2018 Nov 16; 247(3). PMID: 30430577    Free PMC article.
Circulating tumor DNA dynamics using patient-customized assays are associated with outcome in neoadjuvantly treated breast cancer.
Timothy M Butler, Christopher T Boniface, +6 authors, Paul T Spellman.
Cold Spring Harb Mol Case Stud, 2019 Mar 06; 5(2). PMID: 30833418    Free PMC article.
Estimating the number of genetic mutations (hits) required for carcinogenesis based on the distribution of somatic mutations.
Ramu Anandakrishnan, Robin T Varghese, Nicholas A Kinney, Harold R Garner.
PLoS Comput Biol, 2019 Mar 08; 15(3). PMID: 30845172    Free PMC article.
An Interactive Resource to Probe Genetic Diversity and Estimated Ancestry in Cancer Cell Lines.
Julie Dutil, Zhihua Chen, +2 authors, Steven A Eschrich.
Cancer Res, 2019 Mar 22; 79(7). PMID: 30894373    Free PMC article.
A Pooled Analysis of Breastfeeding and Breast Cancer Risk by Hormone Receptor Status in Parous Hispanic Women.
Meera Sangaramoorthy, Lisa M Hines, +7 authors, Esther M John.
Epidemiology, 2019 Apr 10; 30(3). PMID: 30964816    Free PMC article.
Recent advances of therapeutic targets based on the molecular signature in breast cancer: genetic mutations and implications for current treatment paradigms.
Zeinab Safarpour Lima, Mostafa Ghadamzadeh, +3 authors, Ladan Younesi.
J Hematol Oncol, 2019 Apr 13; 12(1). PMID: 30975222    Free PMC article.
Combined quantitative measures of ER, PR, HER2, and KI67 provide more prognostic information than categorical combinations in luminal breast cancer.
Mustapha Abubakar, Jonine Figueroa, +8 authors, Paul D Pharoah.
Mod Pathol, 2019 Apr 13; 32(9). PMID: 30976105    Free PMC article.
U.S. prevalence of endocrine therapy-naïve locally advanced or metastatic breast cancer.
A P Nunes, C Liang, +6 authors, J D Seeger.
Curr Oncol, 2019 May 03; 26(2). PMID: 31043825    Free PMC article.
Factors Associated with Initial Mode of Breast Cancer Detection among Black Women in the Women's Circle of Health Study.
Holly A Szukis, Bo Qin, +10 authors, Adana A M Llanos.
J Oncol, 2019 Jul 30; 2019. PMID: 31354818    Free PMC article.
Breast Cancer Incidence and Mortality by Molecular Subtype: Statewide Age and Racial/Ethnic Disparities in New Jersey.
Aishwarya Kulkarni, Antoinette M Stroup, +3 authors, Adana A M Llanos.
Cancer Health Disparities, 2019 Aug 24; 3. PMID: 31440744    Free PMC article.
Substantial tumor regression in prostate cancer patient with extensive skeletal metastases upon Immunotherapy (APCEDEN): A case report.
Bandana Sharan, Srikanth Chiliveru, +4 authors, Chaitanya Kumar.
Medicine (Baltimore), 2020 Feb 23; 99(8). PMID: 32080073    Free PMC article.
Metabolic Health, Insulin, and Breast Cancer: Why Oncologists Should Care About Insulin.
Lisa D Yee, Joanne E Mortimer, +2 authors, Victoria L Seewaldt.
Front Endocrinol (Lausanne), 2020 Mar 11; 11. PMID: 32153503    Free PMC article.
Breast Cancer in a Caribbean Population in Transition: Design and Implementation of the Atabey Population-Based Case-Control Study of Women in the San Juan Metropolitan Area in Puerto Rico.
Rosa V Rosario-Rosado, Cruz M Nazario, +7 authors, Jo L Freudenheim.
Int J Environ Res Public Health, 2020 Feb 26; 17(4). PMID: 32092890    Free PMC article.
Risk of Osteoporotic Fracture in Patients with Breast Cancer: Meta-Analysis.
Seeyoun Lee, Jun-Il Yoo, +7 authors, Kyung-Hoi Koo.
J Bone Metab, 2020 Mar 20; 27(1). PMID: 32190606    Free PMC article.
Discussion of Trial Designs for Biomarker Identification and Validation Through the Use of Case Studies.
Fang-Shu Ou, Ming-Wen An, Amy S Ruppert, Sumithra J Mandrekar.
JCO Precis Oncol, 2019 Jan 01; 3. PMID: 32190807    Free PMC article.
Decision-making of Adjuvant Chemotherapy for Breast Cancer Patients with Discordant Risk Classifications between Clinical-Pathological Factors and 21-gene Recurrence Score.
Weiqi Gao, Lin Lin, +2 authors, Kunwei Shen.
J Cancer, 2020 Mar 24; 11(9). PMID: 32201521    Free PMC article.
Racial disparities, cancer and response to oxidative stress.
Jie Zhang, Zhi-Wei Ye, +2 authors, Kenneth D Tew.
Adv Cancer Res, 2019 Jul 28; 144. PMID: 31349903    Free PMC article.
Ovarian suppression for adjuvant treatment of hormone receptor-positive early breast cancer.
Kim Tam Bui, Melina L Willson, +2 authors, Annabel Goodwin.
Cochrane Database Syst Rev, 2020 Mar 07; 3. PMID: 32141074    Free PMC article.
Systematic Review.
Outcomes and prognostic factors for women with breast cancer in Malawi.
Victoria M Youngblood, Ruth Nyirenda, +19 authors, Tamiwe Tomoka.
Cancer Causes Control, 2020 Mar 04; 31(4). PMID: 32124187    Free PMC article.
The Immune Microenvironment in Hormone Receptor-Positive Breast Cancer Before and After Preoperative Chemotherapy.
Adrienne G Waks, Daniel G Stover, +26 authors, Sara M Tolaney.
Clin Cancer Res, 2019 May 08; 25(15). PMID: 31061067    Free PMC article.
Efficacy and safety of palbociclib plus endocrine therapy in North American women with hormone receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer.
Karen A Gelmon, Massimo Cristofanilli, +11 authors, Dennis J Slamon.
Breast J, 2019 Aug 27; 26(3). PMID: 31448513    Free PMC article.
Efficacious dose of metformin for breast cancer therapy is determined by cation transporter expression in tumours.
Hao Cai, Ruth S Everett, Dhiren R Thakker.
Br J Pharmacol, 2019 Apr 30; 176(15). PMID: 31032880    Free PMC article.
Bispecific Antibodies and Antibody-Drug Conjugates for Cancer Therapy: Technological Considerations.
Hyunbo Shim.
Biomolecules, 2020 Mar 01; 10(3). PMID: 32111076    Free PMC article.
Subtype-Specific Breast Cancer Incidence Rates in Black versus White Men in the United States.
Hyuna Sung, Carol DeSantis, Ahmedin Jemal.
JNCI Cancer Spectr, 2020 Apr 28; 4(1). PMID: 32337499    Free PMC article.
A Prospective Study of Weight Gain in Women Diagnosed with Early-Stage Invasive Breast Cancer, Ductal Carcinoma In Situ, and Women Without Breast Cancer.
Christine C Ekenga, Xiaoyan Wang, +2 authors, Donna B Jeffe.
J Womens Health (Larchmt), 2019 Aug 29; 29(4). PMID: 31460829    Free PMC article.
Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Is Associated with Indigenous American Ancestry in Latin American Women.
Katie M Marker, Valentina A Zavala, +36 authors, COLUMBUS Consortium.
Cancer Res, 2020 Apr 05; 80(9). PMID: 32245796    Free PMC article.
Race and risk of subsequent aggressive breast cancer following ductal carcinoma in situ.
Ying Liu, Robert West, Jason D Weber, Graham A Colditz.
Cancer, 2019 May 24; 125(18). PMID: 31120565    Free PMC article.
Gene expression comparison between primary triple-negative breast cancer and paired axillary and sentinel lymph node metastasis.
Marissa K Srour, Bowen Gao, +5 authors, Armando E Giuliano.
Breast J, 2019 Nov 13; 26(5). PMID: 31713298    Free PMC article.
Nomograms predicting survival for all four subtypes of breast cancer: a SEER-based population study.
Jianli Chu, Dehong Yang, Ling Wang, Jielai Xia.
Ann Transl Med, 2020 May 16; 8(8). PMID: 32411767    Free PMC article.
Obesity-Altered Adipose Stem Cells Promote Radiation Resistance of Estrogen Receptor Positive Breast Cancer through Paracrine Signaling.
Rachel A Sabol, Vidal A Villela, +8 authors, Bruce A Bunnell.
Int J Mol Sci, 2020 Apr 25; 21(8). PMID: 32326381    Free PMC article.
Hair dye and chemical straightener use and breast cancer risk in a large US population of black and white women.
Carolyn E Eberle, Dale P Sandler, Kyla W Taylor, Alexandra J White.
Int J Cancer, 2019 Dec 05; 147(2). PMID: 31797377    Free PMC article.
The Predictive Role of PIK3CA Mutation Status on PI3K Inhibitors in HR+ Breast Cancer Therapy: A Systematic Review and Meta-Analysis.
Mingming Wang, Jin Li, Jiangsheng Huang, Mei Luo.
Biomed Res Int, 2020 May 29; 2020. PMID: 32461963    Free PMC article.
Systematic Review.
Patients With Breast Cancer: Report From a National Hospital-Based Cancer Registry in Argentina, 2012 to 2016.
María Graciela Abriata, Guillermo Raúl Macías.
J Glob Oncol, 2019 Jan 19; 5. PMID: 30657735    Free PMC article.
Progression-free survival (PFS) and toxicities of palbociclib in a geriatric population.
K Clifton, Yi Min, +3 authors, M Karuturi.
Breast Cancer Res Treat, 2019 Mar 06; 175(3). PMID: 30835017    Free PMC article.
Combination cyclin-dependent kinase 4/6 inhibitors and endocrine therapy versus endocrine monotherapy for hormonal receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: A systematic review and meta-analysis.
Jiani Zheng, Jingxun Wu, +3 authors, Feng Ye.
PLoS One, 2020 Jun 05; 15(6). PMID: 32497134    Free PMC article.
Systematic Review.
Efficacy and Safety of Cyclin-Dependent Kinases 4 and 6 Inhibitors in HR+/HER2- Advanced Breast Cancer.
Ning Xie, Tao Qin, +3 authors, Huangming Hong.
Cancer Manag Res, 2020 Jun 26; 12. PMID: 32581595    Free PMC article.
Comparative Treatment Patterns and Outcomes of Fulvestrant versus Everolimus Plus Exemestane for Postmenopausal Metastatic Breast Cancer Resistant to Aromatase Inhibitors in Real-World Experience.
Yi Li, Yizhao Xie, +7 authors, Biyun Wang.
Ther Clin Risk Manag, 2020 Jul 09; 16. PMID: 32636632    Free PMC article.
A Systematic Review of the Prevalence and Diagnostic Workup of PIK3CA Mutations in HR+/HER2- Metastatic Breast Cancer.
Elizabeth J Anderson, Lea E Mollon, +5 authors, Lisa E Davis.
Int J Breast Cancer, 2020 Jul 09; 2020. PMID: 32637176    Free PMC article.
Current Landscape of Breast Cancer Imaging and Potential Quantitative Imaging Markers of Response in ER-Positive Breast Cancers Treated with Neoadjuvant Therapy.
Ella F Jones, Deep K Hathi, +6 authors, Nola M Hylton.
Cancers (Basel), 2020 Jun 13; 12(6). PMID: 32527022    Free PMC article.
Incidence of pneumonitis/interstitial lung disease induced by HER2-targeting therapy for HER2-positive metastatic breast cancer.
Michelle D Hackshaw, Heather E Danysh, +6 authors, Charles A Powell.
Breast Cancer Res Treat, 2020 Jun 28; 183(1). PMID: 32591987    Free PMC article.
Psychosocial aspects and life project disruption in young women diagnosed with metastatic hormone-sensitive HER2-negative breast cancer.
Mireia Margelí Vila, Sonia Del Barco Berron, +2 authors, Rafael Villanueva Vázquez.
Breast, 2020 Jul 06; 53. PMID: 32623094    Free PMC article.
Male Breast Cancer in the Age of Genetic Testing: An Opportunity for Early Detection, Tailored Therapy, and Surveillance.
Yiming Gao, Samantha L Heller, Linda Moy.
Radiographics, 2018 Aug 04; 38(5). PMID: 30074858    Free PMC article.
Pathologic complete response rate according to HER2 detection methods in HER2-positive breast cancer treated with neoadjuvant systemic therapy.
Melissa Krystel-Whittemore, Jin Xu, +8 authors, Hannah Y Wen.
Breast Cancer Res Treat, 2019 May 31; 177(1). PMID: 31144151    Free PMC article.
Meta-Analysis of Prevalence of Triple-Negative Breast Cancer and Its Clinical Features at Incidence in Indian Patients With Breast Cancer.
Apurv Kulkarni, Devaki A Kelkar, +3 authors, Madhura Kulkarni.
JCO Glob Oncol, 2020 Jul 09; 6. PMID: 32639876    Free PMC article.
Systematic Review.
H2Mab-19, an anti-human epidermal growth factor receptor 2 monoclonal antibody exerts antitumor activity in mouse oral cancer xenografts.
Junko Takei, Mika Kato Kaneko, +3 authors, Yukinari Kato.
Exp Ther Med, 2020 Aug 09; 20(2). PMID: 32765652    Free PMC article.
Prognostic Value of Modified IHC4 Score in Patients with Estrogen Receptor-Positive Metastatic Breast Cancer.
Liang Jin, Kai Chen, +12 authors, Qiang Liu.
Oncologist, 2020 Jun 02; 25(8). PMID: 32476192    Free PMC article.
Decreased expression of the thyroid hormone-inactivating enzyme type 3 deiodinase is associated with lower survival rates in breast cancer.
Iuri Martin Goemann, Vicente Rodrigues Marczyk, +3 authors, Ana Luiza Maia.
Sci Rep, 2020 Aug 19; 10(1). PMID: 32807826    Free PMC article.
Hyaluronan Metabolism is Associated with DNA Repair Genes in Breast and Colorectal Cancer. Screening of Potential Progression Markers Using qPCR.
Ina Sevic, Fiorella Mercedes Spinelli, +7 authors, Laura Alaniz.
Biomedicines, 2020 Jul 03; 8(7). PMID: 32610620    Free PMC article.
Incidence Trends of Breast Cancer Molecular Subtypes by Age and Race/Ethnicity in the US From 2010 to 2016.
Teofilia Acheampong, Rebecca D Kehm, +2 authors, Parisa Tehranifar.
JAMA Netw Open, 2020 Aug 18; 3(8). PMID: 32804214    Free PMC article.
Phase III, Randomized Study of Dual Human Epidermal Growth Factor Receptor 2 (HER2) Blockade With Lapatinib Plus Trastuzumab in Combination With an Aromatase Inhibitor in Postmenopausal Women With HER2-Positive, Hormone Receptor-Positive Metastatic Breast Cancer: ALTERNATIVE.
Stephen R D Johnston, Roberto Hegg, +12 authors, William J Gradishar.
J Clin Oncol, 2017 Dec 16; 36(8). PMID: 29244528    Free PMC article.
Machine learning for RNA sequencing-based intrinsic subtyping of breast cancer.
Silvia Cascianelli, Ivan Molineris, +2 authors, Enzo Medico.
Sci Rep, 2020 Aug 23; 10(1). PMID: 32826944    Free PMC article.
Endocrine therapy-based treatments in hormone receptor-positive/HER2-negative advanced breast cancer: systematic review and network meta-analysis.
Mariana Brandão, Christian Maurer, +7 authors, Matteo Lambertini.
ESMO Open, 2020 Aug 28; 5(4). PMID: 32847835    Free PMC article.
Systematic Review.
Exploration of PCORnet Data Resources for Assessing Use of Molecular-Guided Cancer Treatment.
Ryan M Carnahan, Lemuel R Waitman, +8 authors, Elizabeth A Chrischilles.
JCO Clin Cancer Inform, 2020 Aug 17; 4. PMID: 32795185    Free PMC article.
Cyclin-Dependent Kinase 4/6 Inhibitor (Palbociclib) Induced Aplastic Anemia in a Patient with Metastatic Breast Cancer.
Stanley Madu Nwabudike, Camille V Edwards, +3 authors, Naomi Ko.
Case Rep Hematol, 2019 Jan 17; 2018. PMID: 30647983    Free PMC article.
Triple-negative breast cancer: the reality in Chile and in Latin America.
Christian Caglevic, Jaime Anabalón, +6 authors, Mauricio Mahave.
Ecancermedicalscience, 2019 Feb 23; 13. PMID: 30792810    Free PMC article.
Neighborhood Social Determinants of Triple Negative Breast Cancer.
Fokhrul Hossain, Denise Danos, +8 authors, Richard Scribner.
Front Public Health, 2019 Mar 06; 7. PMID: 30834239    Free PMC article.
Comparative Analysis of Outcomes and Clinicopathological Characteristics of Synchronous and Metachronous Contralateral Breast Cancer: A Study of the SEER Database.
Ruiyue Qiu, Wen Zhao, +9 authors, Danfeng Dong.
J Breast Cancer, 2019 Jul 10; 22(2). PMID: 31281731    Free PMC article.
Endocrine and Targeted Therapy for Hormone-Receptor-Positive, HER2-Negative Advanced Breast Cancer: Insights to Sequencing Treatment and Overcoming Resistance Based on Clinical Trials.
Rola El Sayed, Lara El Jamal, +3 authors, Hazem Assi.
Front Oncol, 2019 Jul 10; 9. PMID: 31281796    Free PMC article.
The Oncotype Dx Assay in ER-Positive, HER2-Negative Breast Cancer Patients: A Real Life Experience from a Single Cancer Center.
Stephane Thibodeau, Ioannis A Voutsadakis.
Eur J Breast Health, 2019 Jul 18; 15(3). PMID: 31312792    Free PMC article.
The Hedgehog Signaling Pathway: A Viable Target in Breast Cancer?
Priyanka Bhateja, Mathew Cherian, Sarmila Majumder, Bhuvaneswari Ramaswamy.
Cancers (Basel), 2019 Aug 10; 11(8). PMID: 31394751    Free PMC article.
CDK4/6 inhibitors in advanced breast cancer, what is beyond?
Amrallah A Mohammed, Hanaa Rashied, Fifi Mostafa Elsayed.
Oncol Rev, 2019 Aug 28; 13(2). PMID: 31452841    Free PMC article.
Advances in HER2-Positive Breast Cancer: Novel Therapies and Adverse Event Management.
Reshma Mahtani, Lisa Hineman.
J Adv Pract Oncol, 2019 Sep 21; 10(2). PMID: 31538025    Free PMC article.
Loss of progesterone receptor is associated with distinct tyrosine kinase profiles in breast cancer.
Andliena Tahiri, Xavier Tekpli, +6 authors, Vessela N Kristensen.
Breast Cancer Res Treat, 2020 Jul 28; 183(3). PMID: 32710281    Free PMC article.
Health-Related Quality of Life in MONARCH 3: Abemaciclib plus an Aromatase Inhibitor as Initial Therapy in HR+, HER2- Advanced Breast Cancer.
Matthew P Goetz, Miguel Martin, +9 authors, Stephen Johnston.
Oncologist, 2020 Jun 15; 25(9). PMID: 32536013    Free PMC article.
Downregulation of Immortalization-Upregulated Protein Suppresses the Progression of Breast Cancer Cell Lines by Regulating Epithelial-Mesenchymal Transition.
Jialiang Wen, Lizhi Lin, +3 authors, Ouchen Wang.
Cancer Manag Res, 2020 Sep 29; 12. PMID: 32982454    Free PMC article.
Breast cancer subtypes: implications for the treatment and survival of patients in Africa-a prospective cohort study from Mozambique.
Mariana Brandão, Assucena Guisseve, +13 authors, Nuno Lunet.
ESMO Open, 2020 Oct 07; 5(5). PMID: 33020218    Free PMC article.
Real-world survival outcomes of heavily pretreated patients with refractory HR+, HER2-metastatic breast cancer receiving single-agent chemotherapy-a comparison with MONARCH 1.
Hope S Rugo, Veronique Dieras, +14 authors, Sara M Tolaney.
Breast Cancer Res Treat, 2020 Aug 14; 184(1). PMID: 32789591    Free PMC article.
Pharmacologic profiling of patient-derived xenograft models of primary treatment-naïve triple-negative breast cancer.
Reid T Powell, Abena Redwood, +21 authors, Helen Piwnica-Worms.
Sci Rep, 2020 Oct 23; 10(1). PMID: 33087803    Free PMC article.
Efficacy and Safety of Fulvestrant 500mg in Hormone-receptor Positive Human Epidermal Receptor 2 Negative Advanced Breast Cancer: A Real-world Study in China.
Wen Lei, Huiping Li, +5 authors, Hanfang Jiang.
J Cancer, 2020 Oct 14; 11(22). PMID: 33046982    Free PMC article.
Cost-effectiveness analyses demonstrate that observation is superior to sentinel lymph node biopsy for postmenopausal women with HR + breast cancer and negative axillary ultrasound.
Aubriana M McEvoy, Steven Poplack, +7 authors, William E Gillanders.
Breast Cancer Res Treat, 2020 Jul 12; 183(2). PMID: 32651755    Free PMC article.
Invasive breast cancer among Alaska Native women in Alaska.
Sarah H Nash, Garrett Zimpelman, +2 authors, Ellen Provost.
Int J Circumpolar Health, 2019 Jun 27; 78(1). PMID: 31234738    Free PMC article.
Treatment Landscape for Patients with HER2-Positive Metastatic Breast Cancer: A Review on Emerging Treatment Options.
Simon Peter Gampenrieder, Vanessa Castagnaviz, Gabriel Rinnerthaler, Richard Greil.
Cancer Manag Res, 2020 Nov 06; 12. PMID: 33149670    Free PMC article.
Patient and physician factors associated with Oncotype DX and adjuvant chemotherapy utilization for breast cancer patients in New Hampshire, 2010-2016.
Thomas M Schwedhelm, Judy R Rees, +4 authors, Erika L Moen.
BMC Cancer, 2020 Sep 05; 20(1). PMID: 32883270    Free PMC article.
Aspirin use and risk of breast cancer in African American women.
Kimberly A Bertrand, Traci N Bethea, +4 authors, Julie R Palmer.
Breast Cancer Res, 2020 Sep 06; 22(1). PMID: 32887656    Free PMC article.
Racial and ethnic disparities in 21-gene recurrence scores, chemotherapy, and survival among women with hormone receptor-positive, node-negative breast cancer.
Yunan Han, Zhi-Feng Miao, +3 authors, Ying Liu.
Breast Cancer Res Treat, 2020 Sep 16; 184(3). PMID: 32929567    Free PMC article.
Breast Cancer in the United States: A Cross-Sectional Overview.
Nadeem Bilani, Emily C Zabor, +2 authors, Zeina Nahleh.
J Cancer Epidemiol, 2020 Nov 13; 2020. PMID: 33178276    Free PMC article.
Disparities in mortality-to-incidence ratios by race/ethnicity for female breast cancer in New York City, 2002-2016.
Tamar B Nobel, Charles K Asumeng, +4 authors, Jennifer J Brown.
Cancer Med, 2020 Oct 03; 9(21). PMID: 33006431    Free PMC article.
Real-World Patterns of Everolimus Use in Patients with Metastatic Breast Cancer.
Manvi Sharma, Zhigang Duan, +2 authors, Mariana Chavez-MacGregor.
Oncologist, 2020 Jun 02; 25(11). PMID: 32476216    Free PMC article.
Biobanking for Cancer Biomarker Research: Issues and Solutions.
Lise A Matzke, Peter H Watson.
Biomark Insights, 2020 Nov 17; 15. PMID: 33192050    Free PMC article.
Prevalence of breast and ovarian cancer subtypes in Hispanic populations from Puerto Rico.
Ariel Rodriguez-Velazquez, Rosa Velez, +6 authors, Guillermo N Armaiz-Pena.
BMC Cancer, 2018 Nov 30; 18(1). PMID: 30482165    Free PMC article.
Cellular Mechanisms Triggered by the Cotreatment of Resveratrol and Doxorubicin in Breast Cancer: A Translational In Vitro-In Silico Model.
José Eduardo Vargas, Renato Puga, +2 authors, Eduardo Filippi-Chiela.
Oxid Med Cell Longev, 2020 Nov 19; 2020. PMID: 33204396    Free PMC article.
Challenges and achievements of liquid biopsy technologies employed in early breast cancer.
Alfonso Alba-Bernal, Rocío Lavado-Valenzuela, +4 authors, Iñaki Comino-Méndez.
EBioMedicine, 2020 Nov 09; 62. PMID: 33161226    Free PMC article.
Immune-related lncRNAs as predictors of survival in breast cancer: a prognostic signature.
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J Transl Med, 2020 Nov 24; 18(1). PMID: 33225954    Free PMC article.
Therapeutic Strategies for the Management of Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Positive (HR+/HER2+) Breast Cancer: A Review of the Current Literature.
Eirini Thanopoulou, Leila Khader, +5 authors, Valentina Guarneri.
Cancers (Basel), 2020 Nov 14; 12(11). PMID: 33182657    Free PMC article.
Generation of an Oncolytic Herpes Simplex Viral Vector Completely Retargeted to the GDNF Receptor GFRα1 for Specific Infection of Breast Cancer Cells.
Bonnie L Hall, Daniela Leronni, +3 authors, Justus B Cohen.
Int J Mol Sci, 2020 Nov 26; 21(22). PMID: 33233403    Free PMC article.
Molecular Subtypes of Breast Cancers from Myanmar Women: A Study of 91 Cases at Two Pathology Centers
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Asian Pac J Cancer Prev, 2017 Jul 04; 18(6). PMID: 28670879    Free PMC article.
A Phase II Trial of Neoadjuvant MK-2206, an AKT Inhibitor, with Anastrozole in Clinical Stage II or III PIK3CA-Mutant ER-Positive and HER2-Negative Breast Cancer.
Cynthia X Ma, Vera Suman, +31 authors, Matthew J Ellis.
Clin Cancer Res, 2017 Sep 07; 23(22). PMID: 28874413    Free PMC article.
Epidemiological characteristics, clinical outcomes and management patterns of metastatic breast cancer patients in routine clinical care settings of Greece: Results from the EMERGE multicenter retrospective chart review study.
Athanasios Kotsakis, Alexandros Ardavanis, +3 authors, Christos Papadimitriou.
BMC Cancer, 2019 Jan 20; 19(1). PMID: 30658600    Free PMC article.
Molecular subtypes of triple-negative breast cancer in women of different race and ethnicity.
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Oncotarget, 2019 Feb 06; 10(2). PMID: 30719214    Free PMC article.
Systemic treatment and radiotherapy, breast cancer subtypes, and survival after long-term clinical follow-up.
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Breast Cancer Res Treat, 2019 Feb 13; 175(2). PMID: 30746635    Free PMC article.
[Update of the German S3 breast cancer guideline : What is new for pathologists?]
A Lebeau, C Denkert, +2 authors, A Wöckel.
Pathologe, 2019 Mar 09; 40(2). PMID: 30847505
HER2+ breast cancer treatment and cardiotoxicity: monitoring and management.
Guy Jerusalem, Patrizio Lancellotti, Sung-Bae Kim.
Breast Cancer Res Treat, 2019 Jun 06; 177(2). PMID: 31165940    Free PMC article.
Gonadotropin-releasing hormone agonist ovulation trigger-beyond OHSS prevention.
Juan Carlos Castillo, Thor Haahr, María Martínez-Moya, Peter Humaidan.
Ups J Med Sci, 2020 Mar 27; 125(2). PMID: 32208810    Free PMC article.
Osteoporotic Fractures of the Spine, Hip, and Other Locations after Adjuvant Endocrine Therapy with Aromatase Inhibitors in Breast Cancer Patients: a Meta-analysis.
Young Kyun Lee, Eun Gyeong Lee, +5 authors, Seeyoun Lee.
J Korean Med Sci, 2020 Dec 02; 35(46). PMID: 33258332    Free PMC article.
Systematic Review.
Exposure to Endocrine Disrupting Chemicals and Risk of Breast Cancer.
Louisane Eve, Béatrice Fervers, Muriel Le Romancer, Nelly Etienne-Selloum.
Int J Mol Sci, 2020 Dec 04; 21(23). PMID: 33266302    Free PMC article.
Clinical outcomes of breast cancer patients treated in phase I clinical trials at University of Colorado Cancer Center.
Jennifer A Weiss, Andrew Nicklawsky, +9 authors, Jennifer R Diamond.
Cancer Med, 2020 Oct 17; 9(23). PMID: 33063469    Free PMC article.
Prediction of breast cancer molecular subtypes using radiomics signatures of synthetic mammography from digital breast tomosynthesis.
Jinwoo Son, Si Eun Lee, Eun-Kyung Kim, Sungwon Kim.
Sci Rep, 2020 Dec 11; 10(1). PMID: 33299040    Free PMC article.
The Contribution of Germline Predisposition Gene Mutations to Clinical Subtypes of Invasive Breast Cancer From a Clinical Genetic Testing Cohort.
Chunling Hu, Eric C Polley, +10 authors, Fergus J Couch.
J Natl Cancer Inst, 2020 Feb 25; 112(12). PMID: 32091585    Free PMC article.
Risk factors and prediction of second primary cancer in primary female non-metastatic breast cancer survivors.
Xiwen Qian, Huixun Jia, +3 authors, Zhenyu Wu.
Aging (Albany NY), 2020 Oct 14; 12(19). PMID: 33049710    Free PMC article.
Inhibiting CDK4/6 in Breast Cancer with Palbociclib, Ribociclib, and Abemaciclib: Similarities and Differences.
C Louwrens Braal, Elisabeth M Jongbloed, +3 authors, Agnes Jager.
Drugs, 2020 Dec 29; 81(3). PMID: 33369721    Free PMC article.
Abemaciclib Combined With Endocrine Therapy for the Adjuvant Treatment of HR+, HER2-, Node-Positive, High-Risk, Early Breast Cancer (monarchE).
Stephen R D Johnston, Nadia Harbeck, +27 authors, monarchE Committee Members and Investigators.
J Clin Oncol, 2020 Sep 22; 38(34). PMID: 32954927    Free PMC article.
Safety and efficacy of abemaciclib plus endocrine therapy in older patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer: an age-specific subgroup analysis of MONARCH 2 and 3 trials.
Matthew P Goetz, Meena Okera, +8 authors, George W Sledge.
Breast Cancer Res Treat, 2021 Jan 05; 186(2). PMID: 33392835    Free PMC article.
Identifying Biomarkers to Predict the Progression and Prognosis of Breast Cancer by Weighted Gene Co-expression Network Analysis.
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Front Genet, 2021 Jan 05; 11. PMID: 33391348    Free PMC article.
Breast Cancer Incidence Trends by Estrogen Receptor Status Among Asian American Ethnic Groups, 1990-2014.
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JNCI Cancer Spectr, 2021 Jan 05; 4(2). PMID: 33392441    Free PMC article.
Triple-negative breast cancer incidence in the United States: ecological correlations with area-level sociodemographics, healthcare, and health behaviors.
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Breast Cancer, 2020 Jul 17; 28(1). PMID: 32671723    Free PMC article.
PI3K/AKT/mTOR Signaling Pathway in Breast Cancer: From Molecular Landscape to Clinical Aspects.
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Int J Mol Sci, 2020 Dec 31; 22(1). PMID: 33375317    Free PMC article.
Racial Disparities in Triple Negative Breast Cancer: A Review of the Role of Biologic and Non-biologic Factors.
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Front Public Health, 2021 Jan 09; 8. PMID: 33415093    Free PMC article.
Concordance of Immunohistochemistry-Based and Gene Expression-Based Subtyping in Breast Cancer.
Johanna Holm, Nancy Yiu-Lin Yu, +4 authors, Kamila Czene.
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[What's new liquid biopsy-PIK3CA testing in breast cancer].
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Pathologe, 2020 Dec 03; 41(Suppl 2). PMID: 33263809
Impact of Hormone Receptor Status on the Behaviour of HER2+ Breast Cancer.
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In Vivo, 2020 Nov 05; 34(6). PMID: 33144452    Free PMC article.
The Use and Concurrent Use of Side Effect Controlling Medications Among Women on Aromatase Inhibitors.
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J Womens Health (Larchmt), 2020 Oct 27; 30(1). PMID: 33103945    Free PMC article.
Bayesian Pathway Analysis for Complex Interactions.
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The HSP-RTK-Akt axis mediates acquired resistance to Ganetespib in HER2-positive breast cancer.
Christopher E Eyermann, John D Haley, Evguenia M Alexandrova.
Cell Death Dis, 2021 Jan 28; 12(1). PMID: 33500390    Free PMC article.
Patterns of treatment with everolimus exemestane in hormone receptor-positive HER2-negative metastatic breast cancer in the era of targeted therapy.
Mariya Rozenblit, Sophia Mun, +3 authors, Sarah Mougalian.
Breast Cancer Res, 2021 Jan 31; 23(1). PMID: 33514405    Free PMC article.
Associated factors and outcomes of delaying adjuvant chemotherapy in breast cancer by biologic subtypes: a National Cancer Database study.
Prashanth Ashok Kumar, Shweta Paulraj, +2 authors, Abirami Sivapiragasam.
J Cancer Res Clin Oncol, 2021 Feb 01; 147(8). PMID: 33517468    Free PMC article.
Clinicopathologic features and prognosis of triple-negative breast cancer in China: a retrospective cohort study of patients under 35 years old.
Hao Li, Zhongnan He, +2 authors, Yan Ling.
Int J Clin Exp Pathol, 2021 Feb 04; 14(1). PMID: 33532020    Free PMC article.
Cancer health disparities in racial/ethnic minorities in the United States.
Valentina A Zavala, Paige M Bracci, +28 authors, Laura Fejerman.
Br J Cancer, 2020 Sep 10; 124(2). PMID: 32901135    Free PMC article.
Racial/Ethnic Disparities in Survival after Breast Cancer Diagnosis by Estrogen and Progesterone Receptor Status: A Pooled Analysis.
Esther M John, Valerie McGuire, +9 authors, Anna H Wu.
Cancer Epidemiol Biomarkers Prev, 2020 Dec 24; 30(2). PMID: 33355191    Free PMC article.
Aromatase and CDK4/6 Inhibitor-Induced Musculoskeletal Symptoms: A Systematic Review.
Angeliki Andrikopoulou, Oraianthi Fiste, +2 authors, Flora Zagouri.
Cancers (Basel), 2021 Feb 04; 13(3). PMID: 33530456    Free PMC article.
Research on the Role of Combined Chemotherapy and Radiotherapy in Patients With N+ Non-Metastatic Metaplastic Breast Carcinoma: A Competing Risk Analysis Model Based on the SEER database, 2000 to 2015.
Yifei Ma, Zejian Yang, +6 authors, Can Zhou.
Front Oncol, 2021 Feb 09; 10. PMID: 33552959    Free PMC article.
Association of PET-based estradiol-challenge test for breast cancer progesterone receptors with response to endocrine therapy.
Farrokh Dehdashti, Ningying Wu, +3 authors, Barry A Siegel.
Nat Commun, 2021 Feb 04; 12(1). PMID: 33531464    Free PMC article.
Optimizing Palbociclib Therapy Across the Age Spectrum: Hypothetical, Illustrative Case Scenarios in HR+, HER2-Metastatic Breast Cancer.
Kimberly Podsada, Joanne C Ryan, Kristi Orbaugh.
J Adv Pract Oncol, 2021 Feb 13; 11(7). PMID: 33575067    Free PMC article.
Breast Cancer Health Disparities in Hispanics/Latinas.
Silvia J Serrano-Gomez, Maria Carolina Sanabria-Salas, Laura Fejerman.
Curr Breast Cancer Rep, 2021 Feb 16; 12(3). PMID: 33584971    Free PMC article.
Regulation of aromatase in cancer.
Deborah Molehin, Fahmida Rasha, Rakhshanda Layeequr Rahman, Kevin Pruitt.
Mol Cell Biochem, 2021 Feb 19; 476(6). PMID: 33599895
Mammary Tumors Growing in the Absence of Growth Hormone Are More Sensitive to Doxorubicin Than Wild-Type Tumors.
Daniel D Lantvit, Christopher J Unterberger, +4 authors, Paul C Marker.
Endocrinology, 2021 Jan 22; 162(4). PMID: 33475144    Free PMC article.
Patient-reported causes of distress predict disparities in time to evaluation and time to treatment after breast cancer diagnosis.
Oluwadamilola M Fayanju, Yi Ren, +5 authors, E Shelley Hwang.
Cancer, 2020 Nov 12; 127(5). PMID: 33175437    Free PMC article.
Preferences of Canadian Patients and Physicians for Treatment of HR+/HER2- Advanced Breast Cancer.
Daniel Stellato, Marroon Thabane, Caitlin Eichten, Thomas E Delea.
Curr Oncol, 2021 Jan 21; 28(1). PMID: 33466914    Free PMC article.
Immune microenvironment and intrinsic subtyping in hormone receptor-positive/HER2-negative breast cancer.
Gaia Griguolo, Maria Vittoria Dieci, +12 authors, Valentina Guarneri.
NPJ Breast Cancer, 2021 Feb 14; 7(1). PMID: 33579951    Free PMC article.
The prevalence of luminal B subtype is higher in older postmenopausal women with ER+/HER2- breast cancer and is associated with inferior outcomes.
Matthew Mills, Casey Liveringhouse, +10 authors, Roberto Diaz.
J Geriatr Oncol, 2020 Aug 30; 12(2). PMID: 32859560    Free PMC article.
The 21-gene recurrence score in node-positive, hormone receptor-positive, HER2-negative breast cancer: a cautionary tale from an NCDB analysis.
Roi Weiser, Waqar Haque, +4 authors, V Suzanne Klimberg.
Breast Cancer Res Treat, 2020 Oct 19; 185(3). PMID: 33070279
First in class dual MDM2/MDMX inhibitor ALRN-6924 enhances antitumor efficacy of chemotherapy in TP53 wild-type hormone receptor-positive breast cancer models.
Seyed Pairawan, Ming Zhao, +15 authors, Funda Meric-Bernstam.
Breast Cancer Res, 2021 Mar 06; 23(1). PMID: 33663585    Free PMC article.
Phase II Trial of Neoadjuvant Carboplatin and Nab-Paclitaxel in Patients with Triple-Negative Breast Cancer.
Yuan Yuan, Jin Sun Lee, +19 authors, Joanne Mortimer.
Oncologist, 2020 Oct 25; 26(3). PMID: 33098195    Free PMC article.
Preclinical Models to Study Obesity and Breast Cancer in Females: Considerations, Caveats, and Tools.
Erin D Giles, Elizabeth A Wellberg.
J Mammary Gland Biol Neoplasia, 2020 Nov 05; 25(4). PMID: 33146844    Free PMC article.
Vascular Inflammation and Cardiovascular Burden in Metastatic Breast Cancer Female Patients Receiving Hormonal Treatment and CDK 4/6 Inhibitors or Everolimus.
Christos Papageorgiou, Flora Zagouri, +8 authors, Konstantinos Toutouzas.
Front Cardiovasc Med, 2021 Mar 19; 8. PMID: 33732735    Free PMC article.
Patterns of de-novo metastasis and breast cancer-specific mortality by race and molecular subtype in the SEER population-based dataset.
Swati Sakhuja, April Deveaux, +5 authors, Tomi Akinyemiju.
Breast Cancer Res Treat, 2020 Nov 12; 186(2). PMID: 33175313
Tucatinib Inhibits Renal Transporters OCT2 and MATE Without Impacting Renal Function in Healthy Subjects.
Ariel R Topletz-Erickson, Anthony J Lee, +8 authors, Christopher J Endres.
J Clin Pharmacol, 2020 Sep 30; 61(4). PMID: 32989831    Free PMC article.
Taxane versus vinorelbine in combination with trastuzumab and pertuzumab for first-line treatment of metastatic HER2-positive breast cancer: a retrospective two-center study.
Daniel Reinhorn, Iryna Kuchuk, +13 authors, Rinat Yerushalmi.
Breast Cancer Res Treat, 2021 Mar 28; 188(2). PMID: 33772709
Integrating biology and access to care in addressing breast cancer disparities: 25 years' research experience in the Carolina Breast Cancer Study.
Marc A Emerson, Katherine E Reeder-Hayes, +6 authors, Melissa A Troester.
Curr Breast Cancer Rep, 2021 Apr 06; 12(3). PMID: 33815665    Free PMC article.
Approaching Neoadjuvant Therapy in the Management of Early-Stage Breast Cancer.
Tara Hyder, Saveri Bhattacharya, +2 authors, Adam M Brufsky.
Breast Cancer (Dove Med Press), 2021 Apr 10; 13. PMID: 33833568    Free PMC article.
Endocrine Therapy-related Endocrinopathies-Biology, Prevalence and Implications for the Management of Breast Cancer.
Kristy A Brown, Eleni Andreopoulou, Panagiota Andreopoulou.
Oncol Hematol Rev, 2021 Apr 13; 16(1). PMID: 33841882    Free PMC article.
A Review of Modifiable Risk Factors in Young Women for the Prevention of Breast Cancer.
Alex A Daly, Rachel Rolph, Ramsey I Cutress, Ellen R Copson.
Breast Cancer (Dove Med Press), 2021 Apr 23; 13. PMID: 33883932    Free PMC article.
Disparities in Cardiovascular Disease Risk Among Hispanic Breast Cancer Survivors in a Population-Based Cohort.
Qingqing Hu, Chun-Pin Chang, +12 authors, Mia Hashibe.
JNCI Cancer Spectr, 2021 Apr 24; 5(2). PMID: 33889806    Free PMC article.
Crosstalk between progesterone receptor membrane component 1 and estrogen receptor α promotes breast cancer cell proliferation.
Diego A Pedroza, Ramadevi Subramani, +7 authors, Rajkumar Lakshmanaswamy.
Lab Invest, 2021 Apr 28; 101(6). PMID: 33903732
Receptor-Defined Breast Cancer in Five East African Countries and Its Implications for Treatment: Systematic Review and Meta-Analysis.
Pallvi Popli, Elane M Gutterman, +3 authors, Richard Marlink.
JCO Glob Oncol, 2021 Feb 17; 7. PMID: 33591798    Free PMC article.
Systematic Review.
Comparative analysis of triple-negative breast cancer transcriptomics of Kenyan, African American and Caucasian Women.
Mansoor Saleh, Darshan Shimoga Chandrashekar, +9 authors, Upender Manne.
Transl Oncol, 2021 Apr 12; 14(7). PMID: 33839593    Free PMC article.
Clinical therapeutic effects of trastuzumab in HER2-positive breast cancer patients: A protocol for systematic review and meta-analysis.
Chuanming Tong, Chuan Wang, Kun Yang.
Medicine (Baltimore), 2021 Apr 29; 100(17). PMID: 33907141    Free PMC article.
PIK3CA somatic alterations in invasive breast cancers: different spectrum from Caucasians to Chinese detected by next generation sequencing.
Minghan Jia, Ning Liao, +12 authors, Charles M Balch.
Breast Cancer, 2021 Jan 03; 28(3). PMID: 33386585    Free PMC article.
Recommendations from the European Commission Initiative on Breast Cancer for multigene testing to guide the use of adjuvant chemotherapy in patients with early breast cancer, hormone receptor positive, HER-2 negative.
Paolo Giorgi Rossi, Annette Lebeau, +13 authors, ECIBC Contributor Group.
Br J Cancer, 2021 Feb 19; 124(9). PMID: 33597715    Free PMC article.
Changes in initiation of adjuvant endocrine therapy for breast cancer after state health reform.
Kirsten Y Eom, G J van Londen, +3 authors, Lindsay M Sabik.
BMC Cancer, 2021 May 03; 21(1). PMID: 33933027    Free PMC article.
Cost-effectiveness of ribociclib plus letrozole versus palbociclib plus letrozole or letrozole as monotherapy in first-line treatment of postmenopausal women with HR+/HER2- locally advanced or metastatic breast cancer: a Brazilian private payer perspective.
Anna Maria Buehler, Gabriela Castilho, Pierre-Alexandre Dionne, Stephen Stefani.
Ther Adv Med Oncol, 2021 May 06; 13. PMID: 33948121    Free PMC article.
Paired tumor sequencing and germline testing in breast cancer management: An experience of a single academic center.
Elizabeth Elliott, Virginia Speare, +11 authors, Lydia Usha.
Cancer Rep (Hoboken), 2020 Sep 04; 3(6). PMID: 32881420    Free PMC article.
PONDx: real-life utilization and decision impact of the 21-gene assay on clinical practice in Italy.
Francesco Cognetti, Riccardo Masetti, +28 authors, Sandro Barni.
NPJ Breast Cancer, 2021 May 07; 7(1). PMID: 33953182    Free PMC article.
Patient-Derived Xenograft Models in Breast Cancer Research.
Deukchae Na, Hyeong-Gon Moon.
Adv Exp Med Biol, 2021 May 14; 1187. PMID: 33983584
Risk of recurrence among patients with HR-positive, HER2-negative, early breast cancer receiving adjuvant endocrine therapy: A systematic review and meta-analysis.
Elizabeth M Salvo, Abril Oliva Ramirez, +4 authors, Imtiaz A Samjoo.
Breast, 2021 Mar 08; 57. PMID: 33677313    Free PMC article.
Gene expression comparison between primary estrogen receptor-positive and triple-negative breast cancer with paired axillary lymph node metastasis.
Marissa K Srour, Ying Qu, +6 authors, Armando E Giuliano.
Breast J, 2021 Jan 20; 27(5). PMID: 33464691    Free PMC article.
Adjuvant Chemotherapy for Low-Clinical-Risk Breast Cancer Defined by Modified Version of Adjuvant! Online: A Propensity Score Matched SEER Analysis.
Jiefeng Huang, Zhiyong Wu, +3 authors, Guosheng Ren.
Breast Care (Basel), 2021 May 21; 16(2). PMID: 34012370    Free PMC article.
The Role of PI3K Inhibition in the Treatment of Breast Cancer, Alone or Combined With Immune Checkpoint Inhibitors.
Zhizhu Zhang, Ann Richmond.
Front Mol Biosci, 2021 May 25; 8. PMID: 34026830    Free PMC article.
Activity of Combined Androgen Receptor Antagonism and Cell Cycle Inhibition in Androgen Receptor Positive Triple Negative Breast Cancer.
Jessica L Christenson, Kathleen I O'Neill, +8 authors, Jennifer K Richer.
Mol Cancer Ther, 2021 Mar 17; 20(6). PMID: 33722849    Free PMC article.
Phenotypic Heterogeneity of Triple-Negative Breast Cancer Mediated by Epithelial-Mesenchymal Plasticity.
Barbora Kvokačková, Ján Remšík, Mohit Kumar Jolly, Karel Souček.
Cancers (Basel), 2021 Jun 03; 13(9). PMID: 34063254    Free PMC article.
The LINC01119-SOCS5 axis as a critical theranostic in triple-negative breast cancer.
Zhenbo Tu, Johannes Schmoellerl, +4 authors, Antoine E Karnoub.
NPJ Breast Cancer, 2021 Jun 02; 7(1). PMID: 34059683    Free PMC article.
The role of CDK4/6 inhibitors in early breast cancer.
Miguel Gil-Gil, Emilio Alba, +5 authors, Antonio Llombart-Cussac.
Breast, 2021 Jun 05; 58. PMID: 34087775    Free PMC article.
Adjuvant endocrine therapy for premenopausal women with breast cancer: Patient adherence and physician prescribing practices in Mexico.
Cynthia Villarreal-Garza, Fernanda Mesa-Chavez, +8 authors, Paula Cabrera-Galeana.
Breast, 2021 Jun 12; 59. PMID: 34116366    Free PMC article.
Patient-Reported Outcomes in Patients With PIK3CA-Mutated Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer From SOLAR-1.
Eva Maria Ciruelos, Hope S Rugo, +16 authors, Fabrice André.
J Clin Oncol, 2021 Mar 30; 39(18). PMID: 33780274    Free PMC article.
Cost-Effectiveness Analysis of Abemaciclib Plus Fulvestrant in the Second-Line Treatment of Women With HR+/HER2- Advanced or Metastatic Breast Cancer: A US Payer Perspective.
Yingcheng Wang, Mingjun Rui, +2 authors, Pingyu Chen.
Front Med (Lausanne), 2021 Jun 22; 8. PMID: 34150798    Free PMC article.
Combination of Pertuzumab and Trastuzumab in the Treatment of HER2-Positive Early Breast Cancer: A Review of the Emerging Clinical Data.
Megan Jagosky, Antoinette R Tan.
Breast Cancer (Dove Med Press), 2021 Jun 25; 13. PMID: 34163239    Free PMC article.
The Guiding Significance of the Number of Positive Sentinel Lymph Nodes in Frozen Section for Intraoperative Axillary Dissection in Early Breast Cancer.
Chenlu Liang, Liuyi Li, +2 authors, Yang Yu.
Cancer Manag Res, 2021 Jun 26; 13. PMID: 34168499    Free PMC article.
Relative Risk of Peripheral Neuropathy With Ado-Trastuzumab Emtansine (T-DM1) Compared to Taxane-Based Regimens in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Cancers: A Systematic Review and Meta-Analysis.
Nusrat Jahan, Shabnam Rehman, Rafiullah Khan, Catherine Jones.
Cureus, 2021 Jul 02; 13(5). PMID: 34194883    Free PMC article.
A Pooled Case-only Analysis of Reproductive Risk Factors and Breast Cancer Subtype Among Black Women in the Southeastern United States.
Maureen Sanderson, Tuya Pal, +15 authors, Loren Lipworth.
Cancer Epidemiol Biomarkers Prev, 2021 May 06; 30(7). PMID: 33947654    Free PMC article.
Tumor-Associated Stromal Cellular Density as a Predictor of Recurrence and Mortality in Breast Cancer: Results from Ethnically Diverse Study Populations.
Mustapha Abubakar, Jing Zhang, +10 authors, Xiaohong Rose Yang.
Cancer Epidemiol Biomarkers Prev, 2021 May 07; 30(7). PMID: 33952648    Free PMC article.
Adherence to anti-estrogen therapy in women with hormone receptor-positive breast cancer utilizing bubble packaging: a pilot study.
Shruti Bhandari, Phuong Ngo, +8 authors, Elizabeth C Riley.
Breast Cancer Res Treat, 2019 Jun 07; 177(2). PMID: 31172406
Iniparib administered weekly or twice-weekly in combination with gemcitabine/carboplatin in patients with metastatic triple-negative breast cancer: a phase II randomized open-label study with pharmacokinetics.
Véronique Diéras, Hervé Bonnefoi, +12 authors, Jaap Verweij.
Breast Cancer Res Treat, 2019 Jun 07; 177(2). PMID: 31172407
Demographic Characteristics and Treatment Patterns Among Patients Receiving Palbociclib for HR+/HER2- Advanced Breast Cancer: A Nationwide Real-World Experience.
Katalin Boér, Gábor Rubovszky, +3 authors, Magdolna Dank.
Onco Targets Ther, 2021 Jul 09; 14. PMID: 34234466    Free PMC article.
Population Pharmacokinetics of Trastuzumab Deruxtecan in Patients With HER2-Positive Breast Cancer and Other Solid Tumors.
Ophelia Yin, Yuan Xiong, +5 authors, Frank LaCreta.
Clin Pharmacol Ther, 2020 Oct 30; 109(5). PMID: 33118153    Free PMC article.
Effectiveness of Alpelisib + Fulvestrant Compared with Real-World Standard Treatment Among Patients with HR+, HER2-, PIK3CA-Mutated Breast Cancer.
Stuart Turner, Stephen Chia, +7 authors, Hope S Rugo.
Oncologist, 2021 Apr 29; 26(7). PMID: 33909934    Free PMC article.
The methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism is associated with breast cancer subtype susceptibility in southwestern China.
Zhen Li, Ji Zhang, +12 authors, Ceshi Chen.
PLoS One, 2021 Jul 10; 16(7). PMID: 34242313    Free PMC article.
Impact of Oncotype DX testing on ER+ breast cancer treatment and survival in the first decade of use.
Evelien Schaafsma, Baoyi Zhang, +3 authors, Chao Cheng.
Breast Cancer Res, 2021 Jul 19; 23(1). PMID: 34274003    Free PMC article.
Adjuvant CDK4/6 inhibitors combined with endocrine therapy in HR-positive, HER2-negative early breast cancer: A meta-analysis of randomized clinical trials.
Hong-Fei Gao, Ying-Yi Lin, +7 authors, Kun Wang.
Breast, 2021 Jul 17; 59. PMID: 34271289    Free PMC article.
Breast Cancer Characteristics in the Population of Survivors Participating in the World Trade Center Environmental Health Center Program 2002-2019.
Alan A Arslan, Yian Zhang, +5 authors, Joan Reibman.
Int J Environ Res Public Health, 2021 Jul 25; 18(14). PMID: 34300003    Free PMC article.
Neoadjuvant everolimus plus letrozole versus fluorouracil, epirubicin and cyclophosphamide for ER-positive, HER2-negative breast cancer: a randomized pilot trial.
Wei Wu, Jiewen Chen, +8 authors, Jieqiong Liu.
BMC Cancer, 2021 Jul 29; 21(1). PMID: 34315439    Free PMC article.
Optimizing treatment selection, and sequencing decisions for Management of HR-Positive, HER2-Negative advanced breast cancer - Proceedings from breast cancer expert group meeting.
Shaheenah Dawood, Maria Konstantionva, +6 authors, Sergio Simon.
BMC Proc, 2021 Aug 11; 15(Suppl 10). PMID: 34372853    Free PMC article.
Multicentric real world evidence with palbociclib in hormone positive HER2 negative metastatic breast cancer in Indian population.
Chaturbhuj Agrawal, Pankaj Goyal, +9 authors, Dinesh Chandra Doval.
Sci Rep, 2021 Aug 12; 11(1). PMID: 34376758    Free PMC article.
Aromatase Inhibitor-Associated Musculoskeletal Syndrome: Understanding Mechanisms and Management.
Tara Hyder, Christopher C Marino, +2 authors, Adam M Brufsky.
Front Endocrinol (Lausanne), 2021 Aug 14; 12. PMID: 34385978    Free PMC article.
Endocrine therapy use and cardiovascular risk in postmenopausal breast cancer survivors.
Anthony A Matthews, Sharon Peacock Hinton, +4 authors, Krishnan Bhaskaran.
Heart, 2020 Nov 13; 107(16). PMID: 33177117    Free PMC article.
Establishment of Prognostic Nomograms for Predicting the Survival of HR-Positive, HER2-Negative Metastatic Breast Cancer Patients Treated with Everolimus.
Fangfang Duan, Chenge Song, +10 authors, Wen Xia.
Drug Des Devel Ther, 2021 Aug 20; 15. PMID: 34408400    Free PMC article.
Population-based recurrence rates among older women with HR-positive, HER2-negative early breast cancer: Clinical risk factors, frailty status, and differences by race.
Jifang Zhou, Jenilee Cueto, +7 authors, Ernest H Law.
Breast, 2021 Aug 23; 59. PMID: 34419726    Free PMC article.
Incidence and Predictors of Diabetes Mellitus after a Diagnosis of Early-Stage Breast Cancer in the Elderly Using Real-World Data.
Melissa K Accordino, Jason D Wright, +5 authors, Dawn L Hershman.
Breast Cancer Res Treat, 2020 Jun 28; 183(1). PMID: 32591988    Free PMC article.
Breast Cancer Treatments: Updates and New Challenges.
Anna Burguin, Caroline Diorio, Francine Durocher.
J Pers Med, 2021 Aug 28; 11(8). PMID: 34442452    Free PMC article.