Review
. 2015 Jan; 33(17):1974-82.
doi: 10.1200/JCO.2014.59.4358.

Immune Checkpoint Blockade in Cancer Therapy

Michael A Postow 1 Margaret K Callahan 1 Jedd D Wolchok 2 
Affiliations
  • PMID: 25605845
  •     92 References
  •     956 citations

Abstract

Immunologic checkpoint blockade with antibodies that target cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and the programmed cell death protein 1 pathway (PD-1/PD-L1) have demonstrated promise in a variety of malignancies. Ipilimumab (CTLA-4) and pembrolizumab (PD-1) are approved by the US Food and Drug Administration for the treatment of advanced melanoma, and additional regulatory approvals are expected across the oncologic spectrum for a variety of other agents that target these pathways. Treatment with both CTLA-4 and PD-1/PD-L1 blockade is associated with a unique pattern of adverse events called immune-related adverse events, and occasionally, unusual kinetics of tumor response are seen. Combination approaches involving CTLA-4 and PD-1/PD-L1 blockade are being investigated to determine whether they enhance the efficacy of either approach alone. Principles learned during the development of CTLA-4 and PD-1/PD-L1 approaches will likely be used as new immunologic checkpoint blocking antibodies begin clinical investigation.

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Tumor immune microenvironment characterization and response to anti-PD-1 therapy.
Mariacarmela Santarpia, Niki Karachaliou.
Cancer Biol Med, 2015 Jul 16; 12(2). PMID: 26175922    Free PMC article.
Combined Trabectedin and anti-PD1 antibody produces a synergistic antitumor effect in a murine model of ovarian cancer.
Zhiqiang Guo, Haolin Wang, +2 authors, Shulan Zhang.
J Transl Med, 2015 Jul 30; 13. PMID: 26219551    Free PMC article.
AFM13: a first-in-class tetravalent bispecific anti-CD30/CD16A antibody for NK cell-mediated immunotherapy.
Jingjing Wu, Jiaping Fu, Mingzhi Zhang, Delong Liu.
J Hematol Oncol, 2015 Aug 02; 8. PMID: 26231785    Free PMC article.
Review.
Are cancer outcomes worse in the presence of HIV infection?
Anna E Coghill, Eric A Engels.
Cancer Epidemiol Biomarkers Prev, 2015 Aug 05; 24(8). PMID: 26240170    Free PMC article.
Relevance of tumor-infiltrating lymphocytes in breast cancer.
Sathana Dushyanthen, Paul A Beavis, +5 authors, Sherene Loi.
BMC Med, 2015 Aug 25; 13. PMID: 26300242    Free PMC article.
Highly Cited. Review.
Immunotherapy of Childhood Sarcomas.
Stephen S Roberts, Alexander J Chou, Nai-Kong V Cheung.
Front Oncol, 2015 Aug 25; 5. PMID: 26301204    Free PMC article.
Review.
Therapeutic efficacy of PD-L1 blockade in a breast cancer model is enhanced by cellular vaccines expressing B7-1 and glycolipid-anchored IL-12.
Erica N Bozeman, Sara He, Yalda Shafizadeh, Periasamy Selvaraj.
Hum Vaccin Immunother, 2015 Aug 27; 12(2). PMID: 26308597    Free PMC article.
Perspectives in the treatment of pancreatic adenocarcinoma.
Angel Cid-Arregui, Victoria Juarez.
World J Gastroenterol, 2015 Aug 27; 21(31). PMID: 26309356    Free PMC article.
Review.
ABCB5 Identifies Immunoregulatory Dermal Cells.
Tobias Schatton, Jun Yang, +21 authors, Markus H Frank.
Cell Rep, 2015 Sep 01; 12(10). PMID: 26321644    Free PMC article.
Blinatumomab: a bispecific T cell engager (BiTE) antibody against CD19/CD3 for refractory acute lymphoid leukemia.
Jingjing Wu, Jiaping Fu, Mingzhi Zhang, Delong Liu.
J Hematol Oncol, 2015 Sep 05; 8. PMID: 26337639    Free PMC article.
Review.
Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling.
Young Kwang Chae, Su Yun Chung, +5 authors, Francis J Giles.
Oncotarget, 2015 Sep 12; 6(35). PMID: 26359351    Free PMC article.
Review.
Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth.
Sonja Kleffel, Christian Posch, +19 authors, Tobias Schatton.
Cell, 2015 Sep 12; 162(6). PMID: 26359984    Free PMC article.
Highly Cited.
Extracting tumor tissue immune status from expression profiles: correlating renal cancer prognosis with tumor-associated immunome.
Omri Teltsh, Angel Porgador, Eitan Rubin.
Oncotarget, 2015 Sep 19; 6(32). PMID: 26384298    Free PMC article.
Isolation of neoantigen-specific T cells from tumor and peripheral lymphocytes.
Cyrille J Cohen, Jared J Gartner, +11 authors, Paul F Robbins.
J Clin Invest, 2015 Sep 22; 125(10). PMID: 26389673    Free PMC article.
Highly Cited.
Clinical significance of tumor-infiltrating immune cells focusing on BTLA and Cbl-b in patients with gallbladder cancer.
Seiji Oguro, Yoshinori Ino, +7 authors, Nobuyoshi Hiraoka.
Cancer Sci, 2015 Sep 24; 106(12). PMID: 26395180    Free PMC article.
Phase II study of the immune-checkpoint inhibitor ipilimumab plus dacarbazine in Japanese patients with previously untreated, unresectable or metastatic melanoma.
N Yamazaki, H Uhara, +8 authors, T Tokudome.
Cancer Chemother Pharmacol, 2015 Sep 27; 76(5). PMID: 26407818    Free PMC article.
How does HTLV-1 cause adult T-cell leukaemia/lymphoma (ATL)?
Charles R M Bangham, Lee Ratner.
Curr Opin Virol, 2015 Sep 29; 14. PMID: 26414684    Free PMC article.
Review.
Signaling pathway and dysregulation of PD1 and its ligands in lymphoid malignancies.
Yi Xia, L Jeffrey Medeiros, Ken H Young.
Biochim Biophys Acta, 2015 Oct 04; 1865(1). PMID: 26432723    Free PMC article.
Review.
Beyond Genomics: Multidimensional Analysis of Cancer Therapy Resistance.
Mary Philip, Andrea Schietinger.
Trends Immunol, 2015 Oct 07; 36(11). PMID: 26440701    Free PMC article.
Intellectual property issues of immune checkpoint inhibitors.
Ulrich Storz.
MAbs, 2015 Oct 16; 8(1). PMID: 26466763    Free PMC article.
The oncolytic peptide LTX-315 induces cell death and DAMP release by mitochondria distortion in human melanoma cells.
Liv-Marie Eike, Nannan Yang, Øystein Rekdal, Baldur Sveinbjørnsson.
Oncotarget, 2015 Oct 17; 6(33). PMID: 26472184    Free PMC article.
Fast Cars and No Brakes: Autologous Stem Cell Transplantation as a Platform for Novel Immunotherapies.
Miguel-Angel Perales, Craig S Sauter, Philippe Armand.
Biol Blood Marrow Transplant, 2015 Oct 21; 22(1). PMID: 26485445    Free PMC article.
Review.
mTOR and MEK1/2 inhibition differentially modulate tumor growth and the immune microenvironment in syngeneic models of oral cavity cancer.
Harrison Cash, Sujay Shah, +4 authors, Clint Allen.
Oncotarget, 2015 Oct 28; 6(34). PMID: 26506415    Free PMC article.
Targeted therapy in gastroesophageal cancers: past, present and future.
Janghee Woo, Stacey A Cohen, Jonathan E Grim.
Gastroenterol Rep (Oxf), 2015 Oct 30; 3(4). PMID: 26510453    Free PMC article.
Clinicopathologic Significance and Prognostic Value of B7 Homolog 1 in Gastric Cancer: A Systematic Review and Meta-Analysis.
Feng Xu, Guosheng Feng, +4 authors, Guangyu An.
Medicine (Baltimore), 2015 Oct 30; 94(43). PMID: 26512615    Free PMC article.
Systematic Review.
Open-label, multicenter, single-arm phase II DeCOG-study of ipilimumab in pretreated patients with different subtypes of metastatic melanoma.
Lisa Zimmer, Thomas K Eigentler, +15 authors, Dirk Schadendorf.
J Transl Med, 2015 Nov 07; 13. PMID: 26541511    Free PMC article.
Programmed death 1 blockade, an Achilles heel for MMR-deficient tumors?
Andy Yingjie Lin, Edward Lin.
J Hematol Oncol, 2015 Nov 07; 8. PMID: 26542241    Free PMC article.
Immunostimulatory Gene Therapy Using Oncolytic Viruses as Vehicles.
Angelica Loskog.
Viruses, 2015 Nov 13; 7(11). PMID: 26561829    Free PMC article.
Review.
ABT-199 (venetoclax) and BCL-2 inhibitors in clinical development.
Shundong Cang, Chaitanya Iragavarapu, +2 authors, Delong Liu.
J Hematol Oncol, 2015 Nov 22; 8. PMID: 26589495    Free PMC article.
Highly Cited. Review.
Overview of current immunotherapeutic strategies for glioma.
Anda-Alexandra Calinescu, Neha Kamran, +3 authors, Maria Graciela Castro.
Immunotherapy, 2015 Nov 26; 7(10). PMID: 26598957    Free PMC article.
Review.
Precision Medicine for Molecularly Targeted Agents and Immunotherapies in Early-Phase Clinical Trials.
Juanita Lopez, Sam Harris, Desam Roda, Timothy A Yap.
Transl Oncogenomics, 2015 Nov 27; 7(Suppl 1). PMID: 26609214    Free PMC article.
Review.
Immune suppressive mechanisms in the tumor microenvironment.
David H Munn, Vincenzo Bronte.
Curr Opin Immunol, 2015 Nov 27; 39. PMID: 26609943    Free PMC article.
Highly Cited. Review.
Muscle-invasive urothelial bladder cancer: an update on systemic therapy.
Hayley Knollman, J Luke Godwin, +3 authors, Daniel M Geynisman.
Ther Adv Urol, 2015 Dec 02; 7(6). PMID: 26622317    Free PMC article.
Review.
Clinicopathological and prognostic value of programmed death ligand-1 (PD-L1) in renal cell carcinoma: a meta-analysis.
Feng Xu, Lingling Xu, +3 authors, Fuquan Liu.
Int J Clin Exp Med, 2015 Dec 03; 8(9). PMID: 26628942    Free PMC article.
Review.
Low stromal Foxp3+ regulatory T-cell density is associated with complete response to neoadjuvant chemoradiotherapy in rectal cancer.
M J McCoy, C Hemmings, +6 authors, C F Platell.
Br J Cancer, 2015 Dec 10; 113(12). PMID: 26645238    Free PMC article.
IL-10: Expanding the Immune Oncology Horizon.
Ivan H Chan, Victoria Wu, +2 authors, John B Mumm.
Receptors Clin Investig, 2015 Dec 15; 2(4). PMID: 26661378    Free PMC article.
Clinical relevance of host immunity in breast cancer: from TILs to the clinic.
Peter Savas, Roberto Salgado, +4 authors, Sherene Loi.
Nat Rev Clin Oncol, 2015 Dec 17; 13(4). PMID: 26667975
Highly Cited. Review.
Immunotherapy in Tumors.
Sebastian Kobold, Peter Duewell, +3 authors, Stefan Endres.
Dtsch Arztebl Int, 2015 Dec 17; 112(48). PMID: 26667979    Free PMC article.
Review.
Importance of immunopharmacogenomics in cancer treatment: Patient selection and monitoring for immune checkpoint antibodies.
Noura Choudhury, Yusuke Nakamura.
Cancer Sci, 2015 Dec 19; 107(2). PMID: 26678880    Free PMC article.
Review.
Influence of immunoglobulin isotype on therapeutic antibody function.
Stephen A Beers, Martin J Glennie, Ann L White.
Blood, 2016 Jan 15; 127(9). PMID: 26764357    Free PMC article.
Review.
Clinical Options in Relapsed or Refractory Hodgkin Lymphoma: An Updated Review.
Roberta Fedele, Massimo Martino, +3 authors, Fortunato Morabito.
J Immunol Res, 2016 Jan 21; 2015. PMID: 26788526    Free PMC article.
Review.
Programmed cell death protein-1/programmed cell death ligand-1 pathway inhibition and predictive biomarkers: understanding transforming growth factor-beta role.
Mariacarmela Santarpia, María González-Cao, +3 authors, Rafael Rosell.
Transl Lung Cancer Res, 2016 Jan 23; 4(6). PMID: 26798582    Free PMC article.
Review.
Bacille-Calmette-Guerin non-responders: how to manage.
Friedrich-Carl von Rundstedt, Seth P Lerner.
Transl Androl Urol, 2016 Jan 28; 4(3). PMID: 26816828    Free PMC article.
Review.
Pembrolizumab: A Review in Advanced Melanoma.
Emma D Deeks.
Drugs, 2016 Feb 06; 76(3). PMID: 26846323
Review.
Cellular Adjuvant Properties, Direct Cytotoxicity of Re-differentiated Vα24 Invariant NKT-like Cells from Human Induced Pluripotent Stem Cells.
Shuichi Kitayama, Rong Zhang, +13 authors, Shin Kaneko.
Stem Cell Reports, 2016 Feb 11; 6(2). PMID: 26862702    Free PMC article.
Cell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand Recognition.
Joanna Brzostek, Nicholas R J Gascoigne, Vasily Rybakin.
Front Immunol, 2016 Feb 13; 7. PMID: 26870040    Free PMC article.
Review.
Tumor infiltrating lymphocytes and survival in patients with head and neck squamous cell carcinoma.
Nghia Nguyen, Emily Bellile, +15 authors, Head and Neck SPORE Program Investigators.
Head Neck, 2016 Feb 18; 38(7). PMID: 26879675    Free PMC article.
Highly Cited.
Immunotherapy for Gastric Cancer: A Focus on Immune Checkpoints.
Maria Alsina, Markus Moehler, +2 authors, Josep Tabernero.
Target Oncol, 2016 Feb 18; 11(4). PMID: 26880697
Review.
PD-1/PD-L1 blockade in cancer treatment: perspectives and issues.
Junzo Hamanishi, Masaki Mandai, +3 authors, Ikuo Konishi.
Int J Clin Oncol, 2016 Feb 24; 21(3). PMID: 26899259    Free PMC article.
Highly Cited. Review.
Drug resistance in cancer: molecular evolution and compensatory proliferation.
Ran Friedman.
Oncotarget, 2016 Feb 26; 7(11). PMID: 26909596    Free PMC article.
Tumor CTLA-4 overexpression predicts poor survival in patients with nasopharyngeal carcinoma.
Pei-Yu Huang, Shan-Shan Guo, +7 authors, Hai-Qiang Mai.
Oncotarget, 2016 Feb 27; 7(11). PMID: 26918337    Free PMC article.
Immunotherapy and Novel Combinations in Oncology: Current Landscape, Challenges, and Opportunities.
K M Morrissey, T M Yuraszeck, +2 authors, S Kasichayanula.
Clin Transl Sci, 2016 Mar 01; 9(2). PMID: 26924066    Free PMC article.
Highly Cited. Review.
The prevalence and clinicopathological features of programmed death-ligand 1 (PD-L1) expression: a pooled analysis of literatures.
Ziying Lin, Yutong Xu, +4 authors, Wenhua Liang.
Oncotarget, 2016 Mar 02; 7(12). PMID: 26930715    Free PMC article.
B7-H4 is a positive regulator of antitumor immunity.
Ramtin Rahbar, Pamela S Ohashi.
Oncoimmunology, 2016 Mar 05; 5(1). PMID: 26942059    Free PMC article.
The Basis of Oncoimmunology.
A Karolina Palucka, Lisa M Coussens.
Cell, 2016 Mar 12; 164(6). PMID: 26967289    Free PMC article.
Highly Cited. Review.
A Chimeric Switch-Receptor Targeting PD1 Augments the Efficacy of Second-Generation CAR T Cells in Advanced Solid Tumors.
Xiaojun Liu, Raghuveer Ranganathan, +8 authors, Edmund K Moon.
Cancer Res, 2016 Mar 17; 76(6). PMID: 26979791    Free PMC article.
Highly Cited.
Systemic inflammation in a melanoma patient treated with immune checkpoint inhibitors-an autopsy study.
Viktor H Koelzer, Sacha I Rothschild, +7 authors, Kirsten D Mertz.
J Immunother Cancer, 2016 Mar 17; 4. PMID: 26981243    Free PMC article.
Highly Cited.
The Efficacy and Safety of Programmed Cell Death 1 and Programmed Cell Death 1 Ligand Inhibitors for Advanced Melanoma: A Meta-Analysis of Clinical Trials Following the PRISMA Guidelines.
Xiuwen Guan, Haijuan Wang, +3 authors, Binghe Xu.
Medicine (Baltimore), 2016 Mar 18; 95(11). PMID: 26986169    Free PMC article.
Review.
Release the hounds: virotherapy with immunotherapy.
Tapan M Kadia.
Blood, 2016 Mar 19; 127(11). PMID: 26989187    Free PMC article.
Emerging therapeutic targets in metastatic progression: A focus on breast cancer.
Zhuo Li, Yibin Kang.
Pharmacol Ther, 2016 Mar 24; 161. PMID: 27000769    Free PMC article.
Review.
Characterisation and management of dermatologic adverse events to agents targeting the PD-1 receptor.
V R Belum, B Benhuri, +8 authors, M E Lacouture.
Eur J Cancer, 2016 Apr 05; 60. PMID: 27043866    Free PMC article.
Highly Cited. Systematic Review.
Repeated PD-1/PD-L1 monoclonal antibody administration induces fatal xenogeneic hypersensitivity reactions in a murine model of breast cancer.
Christine Mall, Gail D Sckisel, +8 authors, William J Murphy.
Oncoimmunology, 2016 Apr 09; 5(2). PMID: 27057446    Free PMC article.
Opportunities for immunotherapy in microsatellite instable colorectal cancer.
Harm Westdorp, Felix L Fennemann, +7 authors, I Jolanda M de Vries.
Cancer Immunol Immunother, 2016 Apr 10; 65(10). PMID: 27060000    Free PMC article.
Review.
Mechanistic roles of epithelial and immune cell signaling during the development of colitis-associated cancer.
Renuka Subramaniam, Atsushi Mizoguchi, Emiko Mizoguchi.
Cancer Res Front, 2016 Apr 26; 2(1). PMID: 27110580    Free PMC article.
Rational bases for the use of the Immunoscore in routine clinical settings as a prognostic and predictive biomarker in cancer patients.
Amos Kirilovsky, Florence Marliot, +3 authors, Franck Pagès.
Int Immunol, 2016 Apr 29; 28(8). PMID: 27121213    Free PMC article.
Highly Cited. Review.
Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination.
Celine Boutros, Ahmad Tarhini, +14 authors, Caroline Robert.
Nat Rev Clin Oncol, 2016 May 05; 13(8). PMID: 27141885
Highly Cited. Review.
miR-424(322) reverses chemoresistance via T-cell immune response activation by blocking the PD-L1 immune checkpoint.
Shaohua Xu, Zhen Tao, +18 authors, Ke Chen.
Nat Commun, 2016 May 06; 7. PMID: 27147225    Free PMC article.
Highly Cited.
The Immune Revolution in Gastrointestinal Tumours: Leading the Way or Just Following?
Marco Puzzoni, Nicola Silvestris, +13 authors, Mario Scartozzi.
Target Oncol, 2016 May 18; 11(5). PMID: 27184491
Review.
Burden of Nonsynonymous Mutations among TCGA Cancers and Candidate Immune Checkpoint Inhibitor Responses.
Leandro M Colli, Mitchell J Machiela, +3 authors, Stephen J Chanock.
Cancer Res, 2016 May 20; 76(13). PMID: 27197178    Free PMC article.
Highly Cited.
Phase 1 Study of Intravenous Oncolytic Poxvirus (vvDD) in Patients With Advanced Solid Cancers.
Stephanie Downs-Canner, Zong Sheng Guo, +8 authors, David L Bartlett.
Mol Ther, 2016 May 21; 24(8). PMID: 27203445    Free PMC article.
Immunological Mechanisms in Breast Cancer - from Bench to Bedside.
Carsten Denkert, Florian Schütz.
Breast Care (Basel), 2016 May 31; 11(2). PMID: 27239169    Free PMC article.
A Case of Organizing Pneumonia (OP) Associated with Pembrolizumab.
Paraskevi Fragkou, Maria Souli, +3 authors, Anna Koumarianou.
Drug Target Insights, 2016 Jun 04; 10. PMID: 27257369    Free PMC article.
When Genome Maintenance Goes Badly Awry.
Elizabeth M Kass, Mary Ellen Moynahan, Maria Jasin.
Mol Cell, 2016 Jun 04; 62(5). PMID: 27259208    Free PMC article.
Review.
Prognostic and predictive impacts of tumor-infiltrating lymphocytes differ between Triple-negative and HER2-positive breast cancers treated with standard systemic therapies.
Akira I Hida, Yasuaki Sagara, +8 authors, Yasuyo Ohi.
Breast Cancer Res Treat, 2016 Jun 05; 158(1). PMID: 27260189    Free PMC article.
Safety and Efficacy of Durvalumab (MEDI4736), an Anti-Programmed Cell Death Ligand-1 Immune Checkpoint Inhibitor, in Patients With Advanced Urothelial Bladder Cancer.
Christophe Massard, Michael S Gordon, +16 authors, Neil H Segal.
J Clin Oncol, 2016 Jun 09; 34(26). PMID: 27269937    Free PMC article.
Highly Cited.
Clinicopathological features of acute kidney injury associated with immune checkpoint inhibitors.
Frank B Cortazar, Kristen A Marrone, +15 authors, David E Leaf.
Kidney Int, 2016 Jun 11; 90(3). PMID: 27282937    Free PMC article.
Highly Cited.
Triple-negative breast cancer: treatment challenges and solutions.
Joëlle Collignon, Laurence Lousberg, Hélène Schroeder, Guy Jerusalem.
Breast Cancer (Dove Med Press), 2016 Jun 11; 8. PMID: 27284266    Free PMC article.
Highly Cited.
Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.
Asim Saha, Roddy S O'Connor, +32 authors, Bruce R Blazar.
J Clin Invest, 2016 Jun 14; 126(7). PMID: 27294527    Free PMC article.
Checkpoint inhibitors and other novel immunotherapies for advanced renal cell carcinoma.
Maria I Carlo, Martin H Voss, Robert J Motzer.
Nat Rev Urol, 2016 Jun 22; 13(7). PMID: 27324121    Free PMC article.
Review.
Genomic and Epigenomic Alterations in Cancer.
Balabhadrapatruni V S K Chakravarthi, Saroj Nepal, Sooryanarayana Varambally.
Am J Pathol, 2016 Jun 25; 186(7). PMID: 27338107    Free PMC article.
Review.
Immune checkpoint blockade in human cancer therapy: lung cancer and hematologic malignancies.
Murali Janakiram, Vipul Pareek, +2 authors, Xingxing Zang.
Immunotherapy, 2016 Jun 29; 8(7). PMID: 27349980    Free PMC article.
Review.
Immune checkpoint inhibitor combinations in solid tumors: opportunities and challenges.
Chrisann Kyi, Michael A Postow.
Immunotherapy, 2016 Jun 29; 8(7). PMID: 27349981    Free PMC article.
Highly Cited. Review.
Effect of nivolumab on health-related quality of life in patients with treatment-naïve advanced melanoma: results from the phase III CheckMate 066 study.
G V Long, V Atkinson, +10 authors, A P Abernethy.
Ann Oncol, 2016 Jul 14; 27(10). PMID: 27405322    Free PMC article.
Aptamers: A Feasible Technology in Cancer Immunotherapy.
M M Soldevilla, H Villanueva, F Pastor.
J Immunol Res, 2016 Jul 15; 2016. PMID: 27413756    Free PMC article.
Review.
Combinatorial immunotherapeutic approaches to restore the function of anergic tumor-reactive cytotoxic CD8+ T cells.
William L Redmond, Stefanie N Linch.
Hum Vaccin Immunother, 2016 Jul 28; 12(10). PMID: 27459422    Free PMC article.
CXCL12 promoter methylation and PD-L1 expression as prognostic biomarkers in prostate cancer patients.
Diane Goltz, Emily Eva Holmes, +8 authors, Dimo Dietrich.
Oncotarget, 2016 Jul 28; 7(33). PMID: 27462860    Free PMC article.
Unraveling the molecular pathways of DNA-methylation inhibitors: human endogenous retroviruses induce the innate immune response in tumors.
Reiner Strick, Pamela L Strissel, Stephen B Baylin, Katherine B Chiappinelli.
Oncoimmunology, 2016 Jul 29; 5(5). PMID: 27467919    Free PMC article.
Adverse Events Associated with Immune Checkpoint Blockade in Patients with Cancer: A Systematic Review of Case Reports.
Noha Abdel-Wahab, Mohsin Shah, Maria E Suarez-Almazor.
PLoS One, 2016 Jul 30; 11(7). PMID: 27472273    Free PMC article.
Highly Cited. Systematic Review.
High affinity nanobodies against human epidermal growth factor receptor selected on cells by E. coli display.
Valencio Salema, Carmen Mañas, +5 authors, Luis Ángel Fernández.
MAbs, 2016 Jul 30; 8(7). PMID: 27472381    Free PMC article.
Regulatory T Cells in the Tumor Microenvironment and Cancer Progression: Role and Therapeutic Targeting.
Belal Chaudhary, Eyad Elkord.
Vaccines (Basel), 2016 Aug 12; 4(3). PMID: 27509527    Free PMC article.
Highly Cited. Review.
Mechanistic insights into the oncolytic activity of vesicular stomatitis virus in cancer immunotherapy.
Boris Simovic, Scott R Walsh, Yonghong Wan.
Oncolytic Virother, 2015 Jan 01; 4. PMID: 27512679    Free PMC article.
Review.
Multiple Expressed Endogenous Glioma Epitopes as Novel Vaccines for Gliomas.
Pedro R Lowenstein, Maria G Castro.
Clin Cancer Res, 2016 Aug 16; 22(19). PMID: 27521444    Free PMC article.
Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer.
Benjamin Herzberg, Meghan J Campo, Justin F Gainor.
Oncologist, 2016 Aug 19; 22(1). PMID: 27534574    Free PMC article.
Review.
The efficacy and potential predictive factors of PD-1/PD-L1 blockades in epithelial carcinoma patients: a systematic review and meta analysis.
Yufan Yang, ZhaoFei Pang, +5 authors, Qi Liu.
Oncotarget, 2016 Aug 20; 7(45). PMID: 27542277    Free PMC article.
Systematic Review.
CD73 is associated with poor prognosis in HNSCC.
Zhen-Hu Ren, Cheng-Zhong Lin, +12 authors, Chen-Ping Zhang.
Oncotarget, 2016 Aug 25; 7(38). PMID: 27557512    Free PMC article.
A phase I clinical study of immunotherapy for advanced colorectal cancers using carcinoembryonic antigen-pulsed dendritic cells mixed with tetanus toxoid and subsequent IL-2 treatment.
Ko-Jiunn Liu, Tsu-Yi Chao, +7 authors, Jacqueline Whang-Peng.
J Biomed Sci, 2016 Aug 26; 23(1). PMID: 27558635    Free PMC article.
The European Organization for Research and Treatment of Cancer perspective on designing clinical trials with immune therapeutics.
Jessica Menis, Saskia Litière, Konstantinos Tryfonidis, Vassilis Golfinopoulos.
Ann Transl Med, 2016 Aug 27; 4(14). PMID: 27563654    Free PMC article.
Review.
Selective inhibition of autoimmune exacerbation while preserving the anti-tumor clinical benefit using IL-6 blockade in a patient with advanced melanoma and Crohn's disease: a case report.
Marc Uemura, Van A Trinh, +8 authors, Adi Diab.
J Hematol Oncol, 2016 Sep 07; 9(1). PMID: 27595932    Free PMC article.
A perspective on anti-EGFR therapies targeting triple-negative breast cancer.
Katsuya Nakai, Mien-Chie Hung, Hirohito Yamaguchi.
Am J Cancer Res, 2016 Sep 21; 6(8). PMID: 27648353    Free PMC article.
Highly Cited. Review.
Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors.
Yu Mei, Wenya Linda Bi, +11 authors, Ian F Dunn.
Oncotarget, 2016 Sep 23; 7(47). PMID: 27655724    Free PMC article.
Actionable Intelligence Provided by Pancreatic Cancer Genomic Landscape: Are Targets for Curative Therapy On The Map?
Nathan A Berger.
Transl Cancer Res, 2016 Sep 23; 5(Suppl 2). PMID: 27656419    Free PMC article.
Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors.
Kole T Roybal, Jasper Z Williams, +6 authors, Wendell A Lim.
Cell, 2016 Oct 04; 167(2). PMID: 27693353    Free PMC article.
Highly Cited.
The efficacy and safety of nivolumab in previously treated advanced non-small-cell lung cancer: a meta-analysis of prospective clinical trials.
Jiaxing Huang, Yaxiong Zhang, +7 authors, Li Zhang.
Onco Targets Ther, 2016 Oct 08; 9. PMID: 27713640    Free PMC article.
Development of a programmed cell death ligand-1 immunohistochemical assay validated for analysis of non-small cell lung cancer and head and neck squamous cell carcinoma.
Marlon C Rebelatto, Anita Midha, +8 authors, Jill Walker.
Diagn Pathol, 2016 Oct 09; 11(1). PMID: 27717372    Free PMC article.
Highly Cited.
Incidence and risk of hepatic toxicities with PD-1 inhibitors in cancer patients: a meta-analysis.
Xi Zhang, Yuge Ran, +2 authors, Jinghua Li.
Drug Des Devel Ther, 2016 Oct 13; 10. PMID: 27729774    Free PMC article.
Cancer immunotherapy in patients with preexisting autoimmune disorders.
Marco Donia, Magnus Pedersen, Inge Marie Svane.
Semin Immunopathol, 2016 Oct 13; 39(3). PMID: 27730287
Review.
Molecular pathological epidemiology: new developing frontiers of big data science to study etiologies and pathogenesis.
Tsuyoshi Hamada, NaNa Keum, Reiko Nishihara, Shuji Ogino.
J Gastroenterol, 2016 Oct 16; 52(3). PMID: 27738762    Free PMC article.
Highly Cited. Review.
Antibody-drug conjugates: recent advances in conjugation and linker chemistries.
Kyoji Tsuchikama, Zhiqiang An.
Protein Cell, 2016 Oct 16; 9(1). PMID: 27743348    Free PMC article.
Highly Cited. Review.
From 2000 to 2016: Which Second-Line Treatment in Advanced Non-Small Cell Lung Cancer?
Ettore D'Argento, Sabrina Rossi, +4 authors, Carlo Barone.
Curr Treat Options Oncol, 2016 Oct 22; 17(12). PMID: 27766545
Review.
Radiotherapy: Changing the Game in Immunotherapy.
Sandra Demaria, C Norman Coleman, Silvia C Formenti.
Trends Cancer, 2016 Oct 25; 2(6). PMID: 27774519    Free PMC article.
Highly Cited. Review.
Immature myeloid cells in the tumor microenvironment: Implications for immunotherapy.
Neha Kamran, Mayuri Chandran, Pedro R Lowenstein, Maria G Castro.
Clin Immunol, 2016 Nov 04; 189. PMID: 27777083    Free PMC article.
Review.
Soluble programmed death-ligand 1 (sPDL1) and neutrophil-to-lymphocyte ratio (NLR) predicts survival in advanced biliary tract cancer patients treated with palliative chemotherapy.
Hyerim Ha, Ah-Rong Nam, +8 authors, Do-Youn Oh.
Oncotarget, 2016 Oct 27; 7(47). PMID: 27780932    Free PMC article.
Aptamers: A New Technological Platform in Cancer Immunotherapy.
Fernando Pastor.
Pharmaceuticals (Basel), 2016 Oct 27; 9(4). PMID: 27783034    Free PMC article.
Review.
Myeloid-derived suppressor cells and tumor escape from immune surveillance.
Viktor Umansky, Carolin Blattner, +4 authors, Jochen Utikal.
Semin Immunopathol, 2016 Oct 28; 39(3). PMID: 27787613
Review.
[Diagnostics and treatment of cholangiocellular carcinoma].
L Zender, N P Malek.
Internist (Berl), 2016 Nov 09; 57(12). PMID: 27822622
Review.
Pembrolizumab Therapy Triggering an Exacerbation of Preexisting Autoimmune Disease: A Report of 2 Patient Cases.
Sneha D Phadke, Ramez Ghabour, +3 authors, Yousef Zakharia.
J Investig Med High Impact Case Rep, 2016 Nov 09; 4(4). PMID: 27826593    Free PMC article.
Immune Responses to Epidermal Growth Factor Receptor (EGFR) and Their Application for Cancer Treatment.
Tetsuro Sasada, Koichi Azuma, Junya Ohtake, Yuki Fujimoto.
Front Pharmacol, 2016 Nov 12; 7. PMID: 27833557    Free PMC article.
Review.
Squamous cell carcinomas escape immune surveillance via inducing chronic activation and exhaustion of CD8+ T Cells co-expressing PD-1 and LAG-3 inhibitory receptors.
Ameet K Mishra, Tanya Kadoishi, +4 authors, Jing H Wang.
Oncotarget, 2016 Nov 12; 7(49). PMID: 27835902    Free PMC article.
Flow Cytometry-based Assay for the Monitoring of NK Cell Functions.
Sara Tognarelli, Benedikt Jacobs, Nina Staiger, Evelyn Ullrich.
J Vis Exp, 2016 Nov 15; (116). PMID: 27842341    Free PMC article.
Head and neck squamous cell carcinoma: Ambiguous human papillomavirus status, elevated p16, and deleted retinoblastoma 1.
Tim N Beck, Chad H Smith, +4 authors, Ranee Mehra.
Head Neck, 2016 Nov 20; 39(3). PMID: 27859938    Free PMC article.
Review.
Resistance to anticancer immunity in cancer patients: potential strategies to reverse resistance.
B Bonavida, S Chouaib.
Ann Oncol, 2016 Nov 20; 28(3). PMID: 27864216    Free PMC article.
Review.
Elevated regulatory T cells, surface and intracellular CTLA-4 expression and interleukin-17 in the lung cancer microenvironment in humans.
Iwona Kwiecien, Anna Stelmaszczyk-Emmel, +2 authors, Joanna Domagala-Kulawik.
Cancer Immunol Immunother, 2016 Nov 21; 66(2). PMID: 27866241    Free PMC article.
Deubiquitination and Stabilization of PD-L1 by CSN5.
Seung-Oe Lim, Chia-Wei Li, +19 authors, Mien-Chie Hung.
Cancer Cell, 2016 Nov 22; 30(6). PMID: 27866850    Free PMC article.
Highly Cited.
Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors.
Muhammad S Beg, Andrew J Brenner, +7 authors, David S Hong.
Invest New Drugs, 2016 Dec 06; 35(2). PMID: 27917453    Free PMC article.
Highly Cited.
Diversity and collaboration for effective immunotherapy.
Karolina Palucka, Jacques Banchereau.
Nat Med, 2016 Dec 07; 22(12). PMID: 27923023
IL-10 expression defines an immunosuppressive dendritic cell population induced by antitumor therapeutic vaccination.
Diana Llopiz, Marta Ruiz, +7 authors, Pablo Sarobe.
Oncotarget, 2016 Dec 08; 8(2). PMID: 27926522    Free PMC article.
Brain metastasis: Unique challenges and open opportunities.
Frank J Lowery, Dihua Yu.
Biochim Biophys Acta Rev Cancer, 2016 Dec 13; 1867(1). PMID: 27939792    Free PMC article.
Review.
Recent Advances in the Medical Treatment of Recurrent or Metastatic Renal Cell Cancer.
Rekha A Kumbla, Robert A Figlin, Edwin M Posadas.
Drugs, 2016 Dec 21; 77(1). PMID: 27995579
Review.
Angiopoietin-2 as a Biomarker and Target for Immune Checkpoint Therapy.
Xinqi Wu, Anita Giobbie-Hurder, +15 authors, F Stephen Hodi.
Cancer Immunol Res, 2016 Dec 23; 5(1). PMID: 28003187    Free PMC article.
Reprogramming the immunological microenvironment through radiation and targeting Axl.
Todd A Aguilera, Marjan Rafat, +12 authors, Amato J Giaccia.
Nat Commun, 2016 Dec 23; 7. PMID: 28008921    Free PMC article.
Highly Cited.
Very Late Antigen-1 Marks Functional Tumor-Resident CD8 T Cells and Correlates with Survival of Melanoma Patients.
Timothy Murray, Silvia A Fuertes Marraco, +6 authors, Daniel E Speiser.
Front Immunol, 2016 Dec 27; 7. PMID: 28018343    Free PMC article.
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: multiple myeloma, lymphoma, and acute leukemia.
Michael Boyiadzis, Michael R Bishop, +45 authors, Madhav V Dhodapkar.
J Immunother Cancer, 2016 Dec 27; 4. PMID: 28018601    Free PMC article.
The intersection of radiotherapy and immunotherapy: mechanisms and clinical implications.
Michael Spiotto, Yang-Xin Fu, Ralph R Weichselbaum.
Sci Immunol, 2016 Dec 27; 1(3). PMID: 28018989    Free PMC article.
Patient-derived xenograft (PDX) models in basic and translational breast cancer research.
Lacey E Dobrolecki, Susie D Airhart, +29 authors, Michael T Lewis.
Cancer Metastasis Rev, 2016 Dec 28; 35(4). PMID: 28025748    Free PMC article.
Highly Cited. Review.
Potential role of immunotherapy in advanced non-small-cell lung cancer.
Ramon Andrade de Mello, Ana Flávia Veloso, +2 authors, Georgios Antoniou.
Onco Targets Ther, 2016 Dec 30; 10. PMID: 28031719    Free PMC article.
Review.
Challenges and opportunities for checkpoint blockade in T-cell lymphoproliferative disorders.
Tycel Phillips, Sumana Devata, Ryan A Wilcox.
J Immunother Cancer, 2016 Dec 30; 4. PMID: 28031823    Free PMC article.
Review.
Efficacy and Safety of Nivolumab Alone or in Combination With Ipilimumab in Patients With Mucosal Melanoma: A Pooled Analysis.
Sandra P D'Angelo, James Larkin, +19 authors, Jedd D Wolchok.
J Clin Oncol, 2017 Jan 06; 35(2). PMID: 28056206    Free PMC article.
Highly Cited.
Impact of CTLA-4 blockade in conjunction with metronomic chemotherapy on preclinical breast cancer growth.
Karla Parra, Paloma Valenzuela, +10 authors, Giulio Francia.
Br J Cancer, 2017 Jan 06; 116(3). PMID: 28056464    Free PMC article.
Roles of IκB kinase ε in the innate immune defense and beyond.
Junjie Zhang, Mao Tian, Zanxian Xia, Pinghui Feng.
Virol Sin, 2017 Jan 08; 31(6). PMID: 28063014    Free PMC article.
Review.
Increased expression of PD‑L1 by the human papillomavirus 16 E7 oncoprotein inhibits anticancer immunity.
Chaoqi Liu, Jiao Lu, +5 authors, Zhiying Li.
Mol Med Rep, 2017 Jan 12; 15(3). PMID: 28075442    Free PMC article.
GM-CSF signalling blockade and chemotherapeutic agents act in concert to inhibit the function of myeloid-derived suppressor cells in vitro.
Tessa Gargett, Susan N Christo, +4 authors, Michael P Brown.
Clin Transl Immunology, 2017 Jan 17; 5(12). PMID: 28090321    Free PMC article.
Inflammatory bowel disease and cancer response due to anti-CTLA-4: is it in the flora?
Franck Carbonnel, Emilie Soularue, +4 authors, Caroline Robert.
Semin Immunopathol, 2017 Jan 18; 39(3). PMID: 28093620
Review.
Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade.
Nina Eissler, Yumeng Mao, +5 authors, Per Kogner.
Oncoimmunology, 2017 Jan 27; 5(12). PMID: 28123870    Free PMC article.
BTLA identifies dysfunctional PD-1-expressing CD4+ T cells in human hepatocellular carcinoma.
Qiyi Zhao, Zhan-Lian Huang, +2 authors, Dong-Ming Kuang.
Oncoimmunology, 2017 Jan 27; 5(12). PMID: 28123898    Free PMC article.
Systematic Pan-Cancer Analysis Reveals Immune Cell Interactions in the Tumor Microenvironment.
Frederick S Varn, Yue Wang, +2 authors, Chao Cheng.
Cancer Res, 2017 Jan 28; 77(6). PMID: 28126714    Free PMC article.
Highly Cited.
Immunosuppressive Myeloid Cells' Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy.
Neha Kamran, Padma Kadiyala, +7 authors, Maria G Castro.
Mol Ther, 2017 Jan 28; 25(1). PMID: 28129117    Free PMC article.
Highly Cited.
The development of dendritic cell vaccine-based immunotherapies for glioblastoma.
David A Reardon, Duane A Mitchell.
Semin Immunopathol, 2017 Feb 01; 39(2). PMID: 28138787
Review.
The Exportin-1 Inhibitor Selinexor Exerts Superior Antitumor Activity when Combined with T-Cell Checkpoint Inhibitors.
Matthew R Farren, Rebecca C Hennessey, +10 authors, Gregory B Lesinski.
Mol Cancer Ther, 2017 Feb 06; 16(3). PMID: 28148715    Free PMC article.
A randomized phase II trial of personalized peptide vaccine with low dose cyclophosphamide in biliary tract cancer.
Takahisa Shirahama, Daisuke Muroya, +9 authors, Shigeru Yutani.
Cancer Sci, 2017 Feb 12; 108(5). PMID: 28188670    Free PMC article.
Compensatory upregulation of PD-1, LAG-3, and CTLA-4 limits the efficacy of single-agent checkpoint blockade in metastatic ovarian cancer.
Ruea-Yea Huang, Ariel Francois, +2 authors, Kunle Odunsi.
Oncoimmunology, 2017 Feb 16; 6(1). PMID: 28197366    Free PMC article.
Highly Cited.
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer.
Andreas D Hartkopf, Florin-Andrei Taran, +4 authors, Sara Y Brucker.
Breast Care (Basel), 2017 Feb 24; 11(6). PMID: 28228704    Free PMC article.
Review.
Interplay between Immune Checkpoint Proteins and Cellular Metabolism.
Sangbin Lim, Joshua B Phillips, +4 authors, Ming Tan.
Cancer Res, 2017 Mar 02; 77(6). PMID: 28246276    Free PMC article.
Review.
Survival Deficit for HIV-Infected Lymphoma Patients in the National Cancer Database.
Anna E Coghill, Howard D Strickler.
Cancer Epidemiol Biomarkers Prev, 2017 Mar 04; 26(3). PMID: 28254955    Free PMC article.
Anti-PD-L1 atezolizumab-Induced Autoimmune Diabetes: a Case Report and Review of the Literature.
Laura Hickmott, Hugo De La Peña, +4 authors, Avinash Gupta.
Target Oncol, 2017 Mar 04; 12(2). PMID: 28255845
Review.
Impact of gefitinib in early stage treatment on circulating cytokines and lymphocytes for patients with advanced non-small cell lung cancer.
Jin Sheng, Wenfeng Fang, +7 authors, Li Zhang.
Onco Targets Ther, 2017 Mar 07; 10. PMID: 28260924    Free PMC article.
Absence of PD-L1 on tumor cells is associated with reduced MHC I expression and PD-L1 expression increases in recurrent serous ovarian cancer.
Stefanie Aust, Sophie Felix, +7 authors, Dietmar Pils.
Sci Rep, 2017 Mar 08; 7. PMID: 28266500    Free PMC article.
Safety and Tolerability of PD-1/PD-L1 Inhibitors Compared with Chemotherapy in Patients with Advanced Cancer: A Meta-Analysis.
Tomohiro F Nishijima, Shlomit S Shachar, Kirsten A Nyrop, Hyman B Muss.
Oncologist, 2017 Mar 10; 22(4). PMID: 28275115    Free PMC article.
Highly Cited. Systematic Review.
Future strategies for the discovery of therapeutic aptamers.
Sorah Yoon, John J Rossi.
Expert Opin Drug Discov, 2017 Mar 10; 12(4). PMID: 28276706    Free PMC article.
Treatment of lung adenocarcinoma by molecular-targeted therapy and immunotherapy.
Motonobu Saito, Hiroyuki Suzuki, +2 authors, Takashi Kohno.
Surg Today, 2017 Mar 11; 48(1). PMID: 28280984
Review.
Immune Checkpoint Inhibitors in Gliomas.
Aaron C Tan, Amy B Heimberger, Mustafa Khasraw.
Curr Oncol Rep, 2017 Mar 18; 19(4). PMID: 28303490
Review.
Immune checkpoint dysfunction in large and medium vessel vasculitis.
Ryu Watanabe, Hui Zhang, +2 authors, Cornelia M Weyand.
Am J Physiol Heart Circ Physiol, 2017 Mar 21; 312(5). PMID: 28314758    Free PMC article.
Review.
DGK-α: A Checkpoint in Cancer-Mediated Immuno-Inhibition and Target for Immunotherapy.
Elfriede Noessner.
Front Cell Dev Biol, 2017 Mar 21; 5. PMID: 28316970    Free PMC article.
IL-15, TIM-3 and NK cells subsets predict responsiveness to anti-CTLA-4 treatment in melanoma patients.
Rossana Tallerico, Costanza M Cristiani, +21 authors, Ennio Carbone.
Oncoimmunology, 2017 Mar 28; 6(2). PMID: 28344869    Free PMC article.
The differentiation and plasticity of Tc17 cells are regulated by CTLA-4-mediated effects on STATs.
Aditya Arra, Holger Lingel, +6 authors, Monika C Brunner-Weinzierl.
Oncoimmunology, 2017 Mar 28; 6(2). PMID: 28344884    Free PMC article.
Impact of Metabolism on T-Cell Differentiation and Function and Cross Talk with Tumor Microenvironment.
Soumaya Kouidhi, Amel Benammar Elgaaied, Salem Chouaib.
Front Immunol, 2017 Mar 30; 8. PMID: 28348562    Free PMC article.
Review.
Systematic literature review of efficacy, safety and tolerability outcomes of chemotherapy regimens in patients with metastatic Merkel cell carcinoma.
Paul Nghiem, Howard L Kaufman, +3 authors, Jürgen C Becker.
Future Oncol, 2017 Mar 30; 13(14). PMID: 28350180    Free PMC article.
Systematic Review.
Priming is key to effective incorporation of image-guided thermal ablation into immunotherapy protocols.
Matthew T Silvestrini, Elizabeth S Ingham, +12 authors, Katherine W Ferrara.
JCI Insight, 2017 Mar 30; 2(6). PMID: 28352658    Free PMC article.
Cancer immunotherapy: how low-level ionizing radiation can play a key role.
Marek K Janiak, Marta Wincenciak, +2 authors, Edward J Calabrese.
Cancer Immunol Immunother, 2017 Apr 01; 66(7). PMID: 28361232    Free PMC article.
Review.
Avelumab, an Anti-Programmed Death-Ligand 1 Antibody, In Patients With Refractory Metastatic Urothelial Carcinoma: Results From a Multicenter, Phase Ib Study.
Andrea B Apolo, Jeffrey R Infante, +14 authors, James L Gulley.
J Clin Oncol, 2017 Apr 05; 35(19). PMID: 28375787    Free PMC article.
Highly Cited.
Shifting the balance of power? The combination of oncolytic virotherapy and immune checkpoint blockade for glioblastoma treatment.
Sean E Lawler.
Neuro Oncol, 2017 Apr 06; 19(4). PMID: 28379450    Free PMC article.
Preclinical Melanoma Imaging with 68Ga-Labeled α-Melanocyte-Stimulating Hormone Derivatives Using PET.
Chengcheng Zhang, Zhengxing Zhang, +5 authors, François Bénard.
Theranostics, 2017 Apr 07; 7(4). PMID: 28382155    Free PMC article.
No association between prediagnosis exercise and survival in patients with high-risk primary melanoma: A population-based study.
Emily Schwitzer, Irene Orlow, +6 authors, GEM Study Group.
Pigment Cell Melanoma Res, 2017 Apr 12; 30(4). PMID: 28397350    Free PMC article.
Tumor immunotherapy: drug-induced neoantigens (xenogenization) and immune checkpoint inhibitors.
Ornella Franzese, Francesco Torino, +5 authors, Stefania D'Atri.
Oncotarget, 2017 Apr 14; 8(25). PMID: 28404974    Free PMC article.
Review.
Overcoming resistance to HER2-targeted therapy with a novel HER2/CD3 bispecific antibody.
Andres Lopez-Albaitero, Hong Xu, +8 authors, Nai-Kong V Cheung.
Oncoimmunology, 2017 Apr 14; 6(3). PMID: 28405494    Free PMC article.
Tumor SQSTM1 (p62) expression and T cells in colorectal cancer.
Keisuke Kosumi, Yohei Masugi, +20 authors, Reiko Nishihara.
Oncoimmunology, 2017 Apr 14; 6(3). PMID: 28405513    Free PMC article.
Aspirin Use and Colorectal Cancer Survival According to Tumor CD274 (Programmed Cell Death 1 Ligand 1) Expression Status.
Tsuyoshi Hamada, Yin Cao, +25 authors, Shuji Ogino.
J Clin Oncol, 2017 Apr 14; 35(16). PMID: 28406723    Free PMC article.
Highly Cited.
Avelumab: clinical trial innovation and collaboration to advance anti-PD-L1 immunotherapy.
K Chin, V K Chand, D S A Nuyten.
Ann Oncol, 2017 Apr 14; 28(7). PMID: 28407031    Free PMC article.
Long non-coding RNAs in cutaneous melanoma: clinical perspectives.
Eva Hulstaert, Lieve Brochez, +2 authors, Pieter Mestdagh.
Oncotarget, 2017 Apr 19; 8(26). PMID: 28415644    Free PMC article.
Review.
Immunotherapeutic approaches for hepatocellular carcinoma.
Vito Longo, Antonio Gnoni, +10 authors, Oronzo Brunetti.
Oncotarget, 2017 Apr 20; 8(20). PMID: 28420805    Free PMC article.
Review.
Expression of Programmed Cell Death Protein 1 by Tumor-Infiltrating Lymphocytes and Tumor Cells is Associated with Advanced Tumor Stage in Patients with Esophageal Adenocarcinoma.
Dagmar Kollmann, Desislava Ignatova, +13 authors, Sebastian F Schoppmann.
Ann Surg Oncol, 2017 Apr 22; 24(9). PMID: 28429196    Free PMC article.
Immunotherapy in hematologic malignancies: past, present, and future.
Annie Im, Steven Z Pavletic.
J Hematol Oncol, 2017 Apr 25; 10(1). PMID: 28434396    Free PMC article.
Review.
A blockade of PD-L1 produced antitumor and antimetastatic effects in an orthotopic mouse pancreatic cancer model via the PI3K/Akt/mTOR signaling pathway.
Lei Zhao, Cheng Li, +6 authors, Chunlin Ge.
Onco Targets Ther, 2017 Apr 27; 10. PMID: 28442920    Free PMC article.
Expanding Diversity and Common Goal of Regulatory T and B Cells. II: In Allergy, Malignancy, and Transplantation.
Grażyna Korczak-Kowalska, Anna Stelmaszczyk-Emmel, +3 authors, Joanna Domagała-Kulawik.
Arch Immunol Ther Exp (Warsz), 2017 May 05; 65(6). PMID: 28470464    Free PMC article.
Review.
Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer.
Woosung Chung, Hye Hyeon Eum, +10 authors, Woong-Yang Park.
Nat Commun, 2017 May 06; 8. PMID: 28474673    Free PMC article.
Highly Cited.
Neurologic Serious Adverse Events Associated with Nivolumab Plus Ipilimumab or Nivolumab Alone in Advanced Melanoma, Including a Case Series of Encephalitis.
James Larkin, Bartosz Chmielowski, +9 authors, David A Reardon.
Oncologist, 2017 May 13; 22(6). PMID: 28495807    Free PMC article.
Highly Cited.
PD-L1 expression on malignant cells is no prerequisite for checkpoint therapy.
Jan Willem Kleinovink, Koen A Marijt, +3 authors, Marieke F Fransen.
Oncoimmunology, 2017 May 17; 6(4). PMID: 28507803    Free PMC article.
Highly Cited.
A novel combination strategy for effectively targeting cancer stem-like cells.
Paul A Beavis, Emma V Petley, Phillip K Darcy.
Immunol Cell Biol, 2017 May 23; 95(7). PMID: 28529324
Japanese Kampo medicine ninjin'yoeito synergistically enhances tumor vaccine effects mediated by CD8+ T cells.
Shun Takaku, Masumi Shimizu, Hidemi Takahashi.
Oncol Lett, 2017 May 23; 13(5). PMID: 28529575    Free PMC article.
Taking a Stab at Cancer; Oncolytic Virus-Mediated Anti-Cancer Vaccination Strategies.
Amelia Sadie Aitken, Dominic Guy Roy, Marie-Claude Bourgeois-Daigneault.
Biomedicines, 2017 May 26; 5(1). PMID: 28536346    Free PMC article.
Review.
Capitalizing on Cancer Specific Replication: Oncolytic Viruses as a Versatile Platform for the Enhancement of Cancer Immunotherapy Strategies.
Donald Bastin, Scott R Walsh, Meena Al Saigh, Yonghong Wan.
Biomedicines, 2017 May 26; 4(3). PMID: 28536388    Free PMC article.
Review.
Emerging treatment options for the management of Hodgkin's lymphoma: clinical utility of nivolumab.
David A Bond, Lapo Alinari.
J Blood Med, 2017 May 27; 8. PMID: 28546779    Free PMC article.
Review.
Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.
Hong Jiang, Yisel Rivera-Molina, +8 authors, Juan Fueyo.
Cancer Res, 2017 Jun 02; 77(14). PMID: 28566332    Free PMC article.
Highly Cited.
Inflammation and Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma: Fighting Against Multiple Opponents.
Farid G Khalafalla, Mohammad W Khan.
Cancer Growth Metastasis, 2017 Jun 06; 10. PMID: 28579826    Free PMC article.
Review.
A prospective pilot study of genome-wide exome and transcriptome profiling in patients with small cell lung cancer progressing after first-line therapy.
Glen J Weiss, Sara A Byron, +6 authors, Timothy G Whitsett.
PLoS One, 2017 Jun 07; 12(6). PMID: 28586388    Free PMC article.
Metabolic reprogramming in the tumour microenvironment: a hallmark shared by cancer cells and T lymphocytes.
Katrina E Allison, Brenda L Coomber, Byram W Bridle.
Immunology, 2017 Jun 18; 152(2). PMID: 28621843    Free PMC article.
Review.
B lymphocytes and cancer: a love-hate relationship.
Grace J Yuen, Ezana Demissie, Shiv Pillai.
Trends Cancer, 2017 Jun 20; 2(12). PMID: 28626801    Free PMC article.
Highly Cited. Review.
Immune Checkpoints as a Target for Colorectal Cancer Treatment.
Alessandro Passardi, Matteo Canale, Martina Valgiusti, Paola Ulivi.
Int J Mol Sci, 2017 Jun 22; 18(6). PMID: 28635639    Free PMC article.
Review.
Nivolumab for Patients With Advanced Melanoma Treated Beyond Progression: Analysis of 2 Phase 3 Clinical Trials.
Georgina V Long, Jeffrey S Weber, +12 authors, Jedd D Wolchok.
JAMA Oncol, 2017 Jul 01; 3(11). PMID: 28662232    Free PMC article.
Highly Cited.
Adoptive transfer of murine T cells expressing a chimeric-PD1-Dap10 receptor as an immunotherapy for lymphoma.
Adam Lynch, William Hawk, +3 authors, Amorette Barber.
Immunology, 2017 Jul 04; 152(3). PMID: 28670716    Free PMC article.
Molecular Effects of Stromal-Selective Targeting by uPAR-Retargeted Oncolytic Virus in Breast Cancer.
Yuqi Jing, Valery Chavez, +5 authors, Jaime R Merchan.
Mol Cancer Res, 2017 Jul 07; 15(10). PMID: 28679779    Free PMC article.
Continuous immunotypes describe human immune variation and predict diverse responses.
Kevin J Kaczorowski, Karthik Shekhar, +5 authors, Petter Brodin.
Proc Natl Acad Sci U S A, 2017 Jul 12; 114(30). PMID: 28696306    Free PMC article.
Immunogenic Chemotherapy Sensitizes Renal Cancer to Immune Checkpoint Blockade Therapy in Preclinical Models.
Shujin Cui.
Med Sci Monit, 2017 Jul 12; 23. PMID: 28697172    Free PMC article.
Anaplastic thyroid carcinoma: from clinicopathology to genetics and advanced therapies.
Eleonora Molinaro, Cristina Romei, +10 authors, Rossella Elisei.
Nat Rev Endocrinol, 2017 Jul 15; 13(11). PMID: 28707679
Highly Cited. Review.
Novel therapeutic strategies in the treatment of triple-negative breast cancer.
Karima Oualla, Heba M El-Zawahry, +7 authors, Tamer M Fouad.
Ther Adv Med Oncol, 2017 Jul 19; 9(7). PMID: 28717401    Free PMC article.
Review.
Clinical implications of the novel cytokine IL-38 expressed in lung adenocarcinoma: Possible association with PD-L1 expression.
Kazuki Takada, Tatsuro Okamoto, +10 authors, Yoshihiko Maehara.
PLoS One, 2017 Jul 21; 12(7). PMID: 28727766    Free PMC article.
Targeting C-type lectin receptors: a high-carbohydrate diet for dendritic cells to improve cancer vaccines.
Dieke van Dinther, Dorian A Stolk, +3 authors, Joke M M den Haan.
J Leukoc Biol, 2017 Jul 22; 102(4). PMID: 28729358    Free PMC article.
Review.
Defining the biological basis of radiomic phenotypes in lung cancer.
Patrick Grossmann, Olya Stringfield, +8 authors, Hugo Jwl Aerts.
Elife, 2017 Jul 22; 6. PMID: 28731408    Free PMC article.
Highly Cited.
Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer.
Manav Korpal, Xiaoling Puyang, +36 authors, Ping Zhu.
Nat Commun, 2017 Jul 26; 8(1). PMID: 28740126    Free PMC article.
Immunotherapy in Gastrointestinal Cancers.
Letizia Procaccio, Marta Schirripa, +9 authors, Sara Lonardi.
Biomed Res Int, 2017 Aug 02; 2017. PMID: 28758114    Free PMC article.
Review.
Checkpoint inhibitors in the treatment of urological malignancies.
Lazar S Popovic, Gorana Matovina-Brko, Maja Popovic.
ESMO Open, 2017 Aug 02; 2(2). PMID: 28761743    Free PMC article.
Review.
Prognostic and predictive values of PD-L1 expression in patients with digestive system cancer: a meta-analysis.
Cong Dai, Meng Wang, +7 authors, Zhijun Dai.
Onco Targets Ther, 2017 Aug 05; 10. PMID: 28769571    Free PMC article.
Emerging role of nivolumab in the management of patients with non-small-cell lung cancer: current data and future perspectives.
Emily Feld, Leora Horn.
Onco Targets Ther, 2017 Aug 05; 10. PMID: 28769573    Free PMC article.
Review.
Escherichia coli surface display for the selection of nanobodies.
Valencio Salema, Luis Ángel Fernández.
Microb Biotechnol, 2017 Aug 05; 10(6). PMID: 28772027    Free PMC article.
Review.
Contrasting effects of cyclophosphamide on anti-CTL-associated protein 4 blockade therapy in two mouse tumor models.
Yuichi Iida, Nanae Harashima, +3 authors, Mamoru Harada.
Cancer Sci, 2017 Aug 09; 108(10). PMID: 28787548    Free PMC article.
Comparative beneficiary effects of immunotherapy against chemotherapy in patients with advanced NSCLC: Meta-analysis and systematic review.
Da-Ping Yu, Xu Cheng, Zhi-Dong Liu, Shao-Fa Xu.
Oncol Lett, 2017 Aug 10; 14(2). PMID: 28789381    Free PMC article.
Recombinant LCMV Vectors Induce Protective Immunity following Homologous and Heterologous Vaccinations.
Jessica Wingerath, Dmitrij Ostroumov, +6 authors, Thomas C Wirth.
Mol Ther, 2017 Aug 15; 25(11). PMID: 28803862    Free PMC article.
Novel landscape of HLA-G isoforms expressed in clear cell renal cell carcinoma patients.
Diana Tronik-Le Roux, Julie Renard, +7 authors, Edgardo D Carosella.
Mol Oncol, 2017 Aug 18; 11(11). PMID: 28815885    Free PMC article.
Efficacy and Safety of Durvalumab in Locally Advanced or Metastatic Urothelial Carcinoma: Updated Results From a Phase 1/2 Open-label Study.
Thomas Powles, Peter H O'Donnell, +16 authors, Noah M Hahn.
JAMA Oncol, 2017 Aug 18; 3(9). PMID: 28817753    Free PMC article.
Highly Cited.
Immuno-oncology Trial Endpoints: Capturing Clinically Meaningful Activity.
Valsamo Anagnostou, Mark Yarchoan, +6 authors, Patrick M Forde.
Clin Cancer Res, 2017 Sep 03; 23(17). PMID: 28864724    Free PMC article.
Immunoregulation by IL-7R-targeting antibody-drug conjugates: overcoming steroid-resistance in cancer and autoimmune disease.
Masahiro Yasunaga, Shino Manabe, Yasuhiro Matsumura.
Sci Rep, 2017 Sep 08; 7(1). PMID: 28878234    Free PMC article.
PD-1 and PD-L1 Checkpoint Signaling Inhibition for Cancer Immunotherapy: Mechanism, Combinations, and Clinical Outcome.
Hashem O Alsaab, Samaresh Sau, +4 authors, Arun K Iyer.
Front Pharmacol, 2017 Sep 08; 8. PMID: 28878676    Free PMC article.
Highly Cited. Review.
Patent trend and competitive analysis of cancer immunotherapy in the United States.
Chia-Lin Pan, Feng-Chi Chen.
Hum Vaccin Immunother, 2017 Sep 08; 13(11). PMID: 28881159    Free PMC article.
Analysis of Class I Major Histocompatibility Complex Gene Transcription in Human Tumors Caused by Human Papillomavirus Infection.
Steven F Gameiro, Ali Zhang, +3 authors, Joe S Mymryk.
Viruses, 2017 Sep 12; 9(9). PMID: 28891951    Free PMC article.
Regulatory T cells impede acute and long-term immunity to blood-stage malaria through CTLA-4.
Samarchith P Kurup, Nyamekye Obeng-Adjei, +5 authors, John T Harty.
Nat Med, 2017 Sep 12; 23(10). PMID: 28892065    Free PMC article.
Safety of checkpoint inhibitors for cancer treatment: strategies for patient monitoring and management of immune-mediated adverse events.
Marianne Davies, Emily A Duffield.
Immunotargets Ther, 2017 Sep 13; 6. PMID: 28894725    Free PMC article.
Review.
Comprehensive Genomic Profiling of 282 Pediatric Low- and High-Grade Gliomas Reveals Genomic Drivers, Tumor Mutational Burden, and Hypermutation Signatures.
Adrienne Johnson, Eric Severson, +26 authors, Shakti H Ramkissoon.
Oncologist, 2017 Sep 16; 22(12). PMID: 28912153    Free PMC article.
Targeted therapies for gastric cancer: failures and hopes from clinical trials.
Maria Apicella, Simona Corso, Silvia Giordano.
Oncotarget, 2017 Sep 17; 8(34). PMID: 28915702    Free PMC article.
Highly Cited. Review.
Tadalafil has biologic activity in human melanoma. Results of a pilot trial with Tadalafil in patients with metastatic Melanoma (TaMe).
Jessica C Hassel, Huanhuan Jiang, +10 authors, Viktor Umansky.
Oncoimmunology, 2017 Sep 22; 6(9). PMID: 28932631    Free PMC article.
Toward Personalized Peptide-Based Cancer Nanovaccines: A Facile and Versatile Synthetic Approach.
Hamilton Kakwere, Elizabeth S Ingham, +6 authors, Katherine W Ferrara.
Bioconjug Chem, 2017 Sep 29; 28(11). PMID: 28956907    Free PMC article.
Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields.
Kristina M Ilieva, Judit Fazekas-Singer, +16 authors, Sophia N Karagiannis.
Front Immunol, 2017 Sep 30; 8. PMID: 28959256    Free PMC article.
Anti-PD-L1 therapy and the onset of diabetes mellitus with positive pancreatic autoantibodies.
Jennifer Way, Alexandra Drakaki, Andrew Drexler, Matthew Freeby.
BMJ Case Rep, 2017 Oct 06; 2017. PMID: 28978581    Free PMC article.
Metabolic characteristics of programmed cell death-ligand 1-expressing lung cancer on 18 F-fluorodeoxyglucose positron emission tomography/computed tomography.
Kazuki Takada, Gouji Toyokawa, +11 authors, Yoshihiko Maehara.
Cancer Med, 2017 Oct 06; 6(11). PMID: 28980429    Free PMC article.
When theory meets experiment: the PD-1 challenge.
Marawan Ahmed, Khaled Barakat.
J Mol Model, 2017 Oct 12; 23(11). PMID: 29019005
Pneumonitis and pneumonitis-related death in cancer patients treated with programmed cell death-1 inhibitors: a systematic review and meta-analysis.
Peng-Fei Cui, Jun-Xun Ma, +3 authors, Yi Hu.
Ther Clin Risk Manag, 2017 Oct 14; 13. PMID: 29026313    Free PMC article.
A cellular platform for the evaluation of immune checkpoint molecules.
Sabrina Jutz, Annika Hennig, +7 authors, Peter Steinberger.
Oncotarget, 2017 Oct 17; 8(39). PMID: 29029399    Free PMC article.
Development of mesenchymal subtype gene signature for clinical application in gastric cancer.
Jeeyun Lee, Razvan Cristescu, +4 authors, Won Ki Kang.
Oncotarget, 2017 Oct 17; 8(39). PMID: 29029513    Free PMC article.
CD4 and CD8 T lymphocyte interplay in controlling tumor growth.
Dmitrij Ostroumov, Nora Fekete-Drimusz, +2 authors, Norman Woller.
Cell Mol Life Sci, 2017 Oct 17; 75(4). PMID: 29032503    Free PMC article.
Review.
Genomic insights into head and neck cancer.
Tim N Beck, Erica A Golemis.
Cancers Head Neck, 2016 Jan 01; 1. PMID: 29034103    Free PMC article.
Characterization and implications of thyroid dysfunction induced by immune checkpoint inhibitors in real-life clinical practice: a long-term prospective study from a referral institution.
F Guaraldi, R La Selva, +6 authors, E Arvat.
J Endocrinol Invest, 2017 Oct 19; 41(5). PMID: 29043574
Current immunotherapeutic strategies in hepatocellular carcinoma: recent advances and future directions.
Hwi Young Kim, Joong-Won Park.
Therap Adv Gastroenterol, 2017 Oct 21; 10(10). PMID: 29051790    Free PMC article.
Review.
Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.
Tamson Moore, Courtney Regan Wagner, +23 authors, Michael I Nishimura.
Cancer Immunol Immunother, 2017 Oct 21; 67(2). PMID: 29052782    Free PMC article.
Synthetic RNA-Based Immunomodulatory Gene Circuits for Cancer Immunotherapy.
Lior Nissim, Ming-Ru Wu, +7 authors, Timothy K Lu.
Cell, 2017 Oct 24; 171(5). PMID: 29056342    Free PMC article.
Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models.
Maurício T Tavares, Sida Shen, +5 authors, Alan P Kozikowski.
ACS Med Chem Lett, 2017 Oct 24; 8(10). PMID: 29057046    Free PMC article.
Identification and Validation of a PD-L1 Binding Peptide for Determination of PDL1 Expression in Tumors.
Charles Caldwell, Cory E Johnson, +3 authors, Raghuraman Kannan.
Sci Rep, 2017 Oct 24; 7(1). PMID: 29057919    Free PMC article.
Avelumab, an anti-PD-L1 antibody, in patients with locally advanced or metastatic breast cancer: a phase 1b JAVELIN Solid Tumor study.
Luc Y Dirix, Istvan Takacs, +15 authors, Erika P Hamilton.
Breast Cancer Res Treat, 2017 Oct 25; 167(3). PMID: 29063313    Free PMC article.
Highly Cited.
An Archaeosome-Adjuvanted Vaccine and Checkpoint Inhibitor Therapy Combination Significantly Enhances Protection from Murine Melanoma.
Felicity C Stark, Risini D Weeratna, +4 authors, Lakshmi Krishnan.
Vaccines (Basel), 2017 Oct 27; 5(4). PMID: 29072624    Free PMC article.
Immune checkpoint inhibitors in renal cell carcinoma.
Kirsty Ross, Rob J Jones.
Clin Sci (Lond), 2017 Oct 29; 131(21). PMID: 29079639    Free PMC article.
Review.
Characterization of Thyroid Disorders in Patients Receiving Immune Checkpoint Inhibition Therapy.
Hyunju Lee, F Stephen Hodi, +13 authors, Le Min.
Cancer Immunol Res, 2017 Oct 29; 5(12). PMID: 29079654    Free PMC article.
Immunotherapy as a Promising Treatment for Prostate Cancer: A Systematic Review.
Marlena Janiczek, Łukasz Szylberg, +5 authors, Andrzej Marszałek.
J Immunol Res, 2017 Nov 08; 2017. PMID: 29109964    Free PMC article.
Systematic Review.
Immune-related adverse events during anticancer immunotherapy: Pathogenesis and management.
Stefania Stucci, Raffaele Palmirotta, +6 authors, Franco Silvestris.
Oncol Lett, 2017 Nov 09; 14(5). PMID: 29113194    Free PMC article.
Molecular diagnostics of lung cancer in the clinic.
Lynette Sholl.
Transl Lung Cancer Res, 2017 Nov 09; 6(5). PMID: 29114472    Free PMC article.
Review.
No patient left behind: The promise of immune priming with epigenetic agents.
Corey A Carter, Bryan T Oronsky, +7 authors, Tony R Reid.
Oncoimmunology, 2017 Nov 11; 6(10). PMID: 29123948    Free PMC article.
Review.
Mevalonate metabolism governs cancer immune surveillance.
Georg Gruenbacher, Martin Thurnher.
Oncoimmunology, 2017 Nov 11; 6(10). PMID: 29123952    Free PMC article.
Review.
Ionizing radiation sensitizes tumors to PD-L1 immune checkpoint blockade in orthotopic murine head and neck squamous cell carcinoma.
Ayman Oweida, Shelby Lennon, +11 authors, Sana D Karam.
Oncoimmunology, 2017 Nov 11; 6(10). PMID: 29123967    Free PMC article.
Targeting Immune Cell Checkpoints during Sepsis.
Naeem K Patil, Yin Guo, Liming Luan, Edward R Sherwood.
Int J Mol Sci, 2017 Nov 15; 18(11). PMID: 29135922    Free PMC article.
Review.
Aviscumine, a recombinant ribosomal inhibitor, increases the antitumor activity of natural killer cells.
Gabriele Gamerith, Arno Amann, +7 authors, Heinz Zwierzina.
Oncol Lett, 2017 Nov 17; 14(5). PMID: 29142605    Free PMC article.
Trial watch: Immune checkpoint blockers for cancer therapy.
Claire Vanpouille-Box, Claire Lhuillier, +10 authors, Lorenzo Galluzzi.
Oncoimmunology, 2017 Nov 18; 6(11). PMID: 29147629    Free PMC article.
Highly Cited. Review.
Anti-Hu-Associated Autoimmune Limbic Encephalitis in a Patient with PD-1 Inhibitor-Responsive Myxoid Chondrosarcoma.
Kyriakos P Papadopoulos, Rebecca S Romero, +3 authors, Matthew Fury.
Oncologist, 2017 Nov 22; 23(1). PMID: 29158368    Free PMC article.
Serial pseudoprogression of metastatic malignant melanoma in a patient treated with nivolumab: a case report.
Yukinori Ozaki, Junichi Shindoh, +14 authors, Toshimi Takano.
BMC Cancer, 2017 Nov 23; 17(1). PMID: 29162045    Free PMC article.
Prognostic value of PD-L1 expression in combination with CD8+ TILs density in patients with surgically resected non-small cell lung cancer.
Hui Yang, Jinpeng Shi, +11 authors, Caicun Zhou.
Cancer Med, 2017 Nov 24; 7(1). PMID: 29168339    Free PMC article.
Will a mAb-Based Immunotherapy Directed against Cancer Stem Cells Be Feasible?
Silvia Santamaria, Marisa Delgado, Leonor Kremer, Jose A Garcia-Sanz.
Front Immunol, 2017 Nov 25; 8. PMID: 29170667    Free PMC article.
Review.
First-in-human Phase 1 CRISPR Gene Editing Cancer Trials: Are We Ready?
Francoise Baylis, Marcus McLeod.
Curr Gene Ther, 2017 Nov 28; 17(4). PMID: 29173170    Free PMC article.
Role of microRNA-33a in regulating the expression of PD-1 in lung adenocarcinoma.
Laura Boldrini, Mirella Giordano, +4 authors, Gabriella Fontanini.
Cancer Cell Int, 2017 Nov 28; 17. PMID: 29176936    Free PMC article.
Modulation of antigen presenting cell functions during chronic HPV infection.
Abate Assefa Bashaw, Graham R Leggatt, +2 authors, Ian H Frazer.
Papillomavirus Res, 2017 Nov 29; 4. PMID: 29179871    Free PMC article.
Review.
Cellular senescence in gastrointestinal diseases: from pathogenesis to therapeutics.
Nina Frey, Sascha Venturelli, Lars Zender, Michael Bitzer.
Nat Rev Gastroenterol Hepatol, 2017 Dec 01; 15(2). PMID: 29184185
Review.
CAR-T cells and combination therapies: What's next in the immunotherapy revolution?
Maria C Ramello, Eric B Haura, Daniel Abate-Daga.
Pharmacol Res, 2017 Dec 06; 129. PMID: 29203440    Free PMC article.
Molecular classification and precision therapy of cancer: immune checkpoint inhibitors.
Yingyan Yu.
Front Med, 2017 Dec 07; 12(2). PMID: 29209918
Analysis of Drug Development Paradigms for Immune Checkpoint Inhibitors.
Denis L Jardim, Débora de Melo Gagliato, Francis J Giles, Razelle Kurzrock.
Clin Cancer Res, 2017 Dec 08; 24(8). PMID: 29212781    Free PMC article.
Review.
Immunotherapy and gene therapy as novel treatments for cancer.
Martha Montserrat Rangel-Sosa, Estuardo Aguilar-Córdova, Augusto Rojas-Martínez.
Colomb Med (Cali), 2017 Dec 08; 48(3). PMID: 29213157    Free PMC article.
Review.
How to evaluate the immune status of lung cancer patients before immunotherapy.
Joanna Domagala-Kulawik, Agata Raniszewska.
Breathe (Sheff), 2017 Dec 12; 13(4). PMID: 29225707    Free PMC article.
Atorvastatin downregulates co-inhibitory receptor expression by targeting Ras-activated mTOR signalling.
Isobel Okoye, Afshin Namdar, +2 authors, Shokrollah Elahi.
Oncotarget, 2017 Dec 13; 8(58). PMID: 29228684    Free PMC article.
Co-relation of overall survival with peripheral blood-based inflammatory biomarkers in advanced stage non-small cell lung cancer treated with anti-programmed cell death-1 therapy: results from a single institutional database.
Abdul Rafeh Naqash, Chipman Robert Geoffrey Stroud, +7 authors, Paul R Walker.
Acta Oncol, 2017 Dec 16; 57(6). PMID: 29241410    Free PMC article.
Case report on the role of radiofrequency-assisted spleen-preserving surgery for splenic metastasis in the era of check-point inhibitors.
Satwinder Mudan, Jayant Kumar, +5 authors, Nagy Habib.
Medicine (Baltimore), 2017 Dec 17; 96(49). PMID: 29245341    Free PMC article.
Synergy of Immune Checkpoint Blockade with a Novel Synthetic Consensus DNA Vaccine Targeting TERT.
Elizabeth K Duperret, Megan C Wise, +8 authors, David B Weiner.
Mol Ther, 2017 Dec 19; 26(2). PMID: 29249395    Free PMC article.
Informatics for cancer immunotherapy.
J Hammerbacher, A Snyder.
Ann Oncol, 2017 Dec 19; 28(suppl_12). PMID: 29253114    Free PMC article.
Review.
TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma.
Florie Bertrand, Anne Montfort, +9 authors, Bruno Ségui.
Nat Commun, 2017 Dec 24; 8(1). PMID: 29273790    Free PMC article.
Highly Cited.
Recent Successes and Future Directions in Immunotherapy of Cutaneous Melanoma.
Hassan Sadozai, Thomas Gruber, Robert Emil Hunger, Mirjam Schenk.
Front Immunol, 2017 Dec 26; 8. PMID: 29276510    Free PMC article.
Review.
How Checkpoint Inhibitors Are Changing the Treatment Paradigm in Solid Tumors: What Advanced Practitioners in Oncology Need to Know.
Marianne Davies.
J Adv Pract Oncol, 2016 Jul 01; 7(5). PMID: 29282426    Free PMC article.
Review.
Immunopharmacogenomics towards personalized cancer immunotherapy targeting neoantigens.
Kazuma Kiyotani, Hiu Ting Chan, Yusuke Nakamura.
Cancer Sci, 2017 Dec 31; 109(3). PMID: 29288513    Free PMC article.
Review.
Activity and Immune Correlates of a Programmed Death-1 Blockade Antibody in the treatment of Refractory Solid Tumors.
Chang Jiang, Xiuyu Cai, +3 authors, Liangping Xia.
J Cancer, 2018 Jan 02; 9(1). PMID: 29290787    Free PMC article.
Immune Checkpoint Inhibitors in Melanoma and HIV Infection.
Antonio Marra, Giosuè Scognamiglio, +6 authors, Francesco Sabbatino.
Open AIDS J, 2018 Jan 02; 11. PMID: 29290886    Free PMC article.
Review.
Blocking CTLA-4 while priming with a whole cell vaccine reshapes the oligoclonal T cell infiltrate and eradicates tumors in an orthotopic glioma model.
Cameron S Field, Martin K Hunn, +3 authors, Ian F Hermans.
Oncoimmunology, 2018 Jan 04; 7(1). PMID: 29296535    Free PMC article.
Risk of gastrointestinal toxicities with PD-1 inhibitors in cancer patients: A meta-analysis of randomized clinical trials.
Wei Wei, Zhibin Luo.
Medicine (Baltimore), 2018 Jan 10; 96(48). PMID: 29310385    Free PMC article.
Dynamics of Immune Checkpoints, Immune System, and BCG in the Treatment of Superficial Bladder Cancer.
Farouk Tijjani Saad, Evren Hincal, Bilgen Kaymakamzade.
Comput Math Methods Med, 2018 Jan 10; 2017. PMID: 29312460    Free PMC article.
PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression.
Haidong Tang, Yong Liang, +18 authors, Yang-Xin Fu.
J Clin Invest, 2018 Jan 18; 128(2). PMID: 29337303    Free PMC article.
Highly Cited.
Prognostic Power of a Tumor Differentiation Gene Signature for Bladder Urothelial Carcinomas.
Qianxing Mo, Fotis Nikolos, +6 authors, Keith Syson Chan.
J Natl Cancer Inst, 2018 Jan 18; 110(5). PMID: 29342309    Free PMC article.
Checkpoint Inhibitors, Palliative Care, or Hospice.
Mellar P Davis, Rajiv Panikkar.
Curr Oncol Rep, 2018 Jan 20; 20(1). PMID: 29349518
Review.
Exceptional Response to Pembrolizumab in a Metastatic, Chemotherapy/Radiation-Resistant Ovarian Cancer Patient Harboring a PD-L1-Genetic Rearrangement.
Stefania Bellone, Natalia Buza, +8 authors, Alessandro D Santin.
Clin Cancer Res, 2018 Jan 21; 24(14). PMID: 29351920    Free PMC article.
Acute Pharmacologic Degradation of a Stable Antigen Enhances Its Direct Presentation on MHC Class I Molecules.
Sarah C Moser, Jane S A Voerman, +2 authors, Christopher Schliehe.
Front Immunol, 2018 Jan 24; 8. PMID: 29358938    Free PMC article.
Clinical Development of PD-1 in Advanced Melanoma.
Rodrigo Ramella Munhoz, Michael Andrew Postow.
Cancer J, 2018 Jan 24; 24(1). PMID: 29360722    Free PMC article.
Review.
Prognostic and clinicopathological significance of PD-L1 in patients with renal cell carcinoma: a meta-analysis based on 1863 individuals.
Zhun Wang, Shuanghe Peng, +5 authors, Yuanjie Niu.
Clin Exp Med, 2018 Jan 25; 18(2). PMID: 29362922
Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells.
Debangshu Samanta, Youngrok Park, +5 authors, Gregg L Semenza.
Proc Natl Acad Sci U S A, 2018 Jan 26; 115(6). PMID: 29367423    Free PMC article.
Highly Cited.
The structure, expression, and multifaceted role of immune-checkpoint protein VISTA as a critical regulator of anti-tumor immunity, autoimmunity, and inflammation.
Wenwen Xu, TạMinh Hiếu, Subramaniam Malarkannan, Li Wang.
Cell Mol Immunol, 2018 Jan 30; 15(5). PMID: 29375120    Free PMC article.
Review.
Phase 2 trial of a multivalent WT1 peptide vaccine (galinpepimut-S) in acute myeloid leukemia.
Peter G Maslak, Tao Dao, +14 authors, David A Scheinberg.
Blood Adv, 2018 Feb 02; 2(3). PMID: 29386195    Free PMC article.
Cloning and expansion of antigen-specific T cells using iPS cell technology: development of "off-the-shelf" T cells for the use in allogeneic transfusion settings.
Hiroshi Kawamoto, Kyoko Masuda, Seiji Nagano, Takuya Maeda.
Int J Hematol, 2018 Feb 02; 107(3). PMID: 29388165
Review.
Analysis of PD1, PDL1, PDL2 expression and T cells infiltration in 1014 gastric cancer patients.
Xiaofang Xing, Jianping Guo, +23 authors, Jiafu Ji.
Oncoimmunology, 2018 Feb 06; 7(3). PMID: 29399387    Free PMC article.
Highly Cited.
Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade.
Jorrit De Waele, Elly Marcq, +14 authors, Evelien Lj Smits.
Oncoimmunology, 2018 Feb 06; 7(3). PMID: 29399410    Free PMC article.
Combination therapy for cancer with oncolytic virus and checkpoint inhibitor: A mathematical model.
Avner Friedman, Xiulan Lai.
PLoS One, 2018 Feb 09; 13(2). PMID: 29420595    Free PMC article.
Herpes Encephalitis: A Mortal Complication in a Patient Treated with Immunosuppressive Drugs because of Immune-Related Adverse Events after Ipilimumab Treatment.
Lieke van Montfort, Caroline M Loos, Monique Anten, Rob L H Jansen.
Case Rep Oncol, 2018 Feb 13; 10(3). PMID: 29430235    Free PMC article.
DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation.
Qian Xiao, Jibo Wu, +14 authors, Dianqing Wu.
Nat Med, 2018 Feb 13; 24(3). PMID: 29431745    Free PMC article.
Highly Cited.
Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia.
Marina Wierz, Sandrine Pierson, +10 authors, Etienne Moussay.
Blood, 2018 Feb 15; 131(14). PMID: 29439955    Free PMC article.
Salmonella enterica Serovar Typhimurium Increases Functional PD-L1 Synergistically with Gamma Interferon in Intestinal Epithelial Cells via Salmonella Pathogenicity Island 2.
J M Sahler, C R Eade, C Altier, J C March.
Infect Immun, 2018 Feb 15; 86(5). PMID: 29440366    Free PMC article.
An Uncoupling of Canonical Phenotypic Markers and Functional Potency of Ex Vivo-Expanded Natural Killer Cells.
Nicole A P Lieberman, Kole DeGolier, +6 authors, Courtney A Crane.
Front Immunol, 2018 Feb 20; 9. PMID: 29456538    Free PMC article.
Phenotypic and Functional Properties of Tumor-Infiltrating Regulatory T Cells.
Gap Ryol Lee.
Mediators Inflamm, 2018 Feb 22; 2017. PMID: 29463952    Free PMC article.
Review.
The presence of PD-1 positive tumor infiltrating lymphocytes in triple negative breast cancers is associated with a favorable outcome of disease.
Gero Brockhoff, Stephan Seitz, +4 authors, Anja Kathrin Wege.
Oncotarget, 2018 Feb 22; 9(5). PMID: 29464065    Free PMC article.
Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy.
Rajani Ravi, Kimberly A Noonan, +13 authors, Atul Bedi.
Nat Commun, 2018 Feb 23; 9(1). PMID: 29467463    Free PMC article.
Highly Cited.
Safety profile of avelumab in patients with advanced solid tumors: A pooled analysis of data from the phase 1 JAVELIN solid tumor and phase 2 JAVELIN Merkel 200 clinical trials.
Karen Kelly, Jeffrey R Infante, +8 authors, James L Gulley.
Cancer, 2018 Feb 23; 124(9). PMID: 29469949    Free PMC article.
T-cell Immunotherapies and the Role of Nonclinical Assessment: The Balance between Efficacy and Pathology.
Michaela E Sharpe.
Toxicol Pathol, 2018 Feb 24; 46(2). PMID: 29471776    Free PMC article.
Review.
BRAF and MEK Inhibitors: Use and Resistance in BRAF-Mutated Cancers.
Jaquelyn N Sanchez, Ton Wang, Mark S Cohen.
Drugs, 2018 Mar 01; 78(5). PMID: 29488071    Free PMC article.
Review.
Immune Monitoring of Cancer Patients Prior to and During CTLA-4 or PD-1/PD-L1 Inhibitor Treatment.
Antje Tunger, Maximilian Kießler, +4 authors, Marc Schmitz.
Biomedicines, 2018 Mar 02; 6(1). PMID: 29494517    Free PMC article.
Review.
The Rationale and Emerging Use of Neoadjuvant Immune Checkpoint Blockade for Solid Malignancies.
Emily Z Keung, Esosa U Ukponmwan, Alexandria P Cogdill, Jennifer A Wargo.
Ann Surg Oncol, 2018 Mar 04; 25(7). PMID: 29500764    Free PMC article.
Prognostic significance of circulating soluble programmed death ligand-1 in patients with solid tumors: A meta-analysis.
Wei Wei, Bin Xu, +3 authors, Changping Wu.
Medicine (Baltimore), 2018 Mar 06; 97(3). PMID: 29504990    Free PMC article.
New horizons from immunotherapy in malignant pleural mesothelioma.
Luana Calabrò, Giulia Rossi, Michele Maio.
J Thorac Dis, 2018 Mar 07; 10(Suppl 2). PMID: 29507802    Free PMC article.
Review.
Current Molecular Targeted Therapies for Bone and Soft Tissue Sarcomas.
Kenji Nakano, Shunji Takahashi.
Int J Mol Sci, 2018 Mar 08; 19(3). PMID: 29510588    Free PMC article.
Review.
Incidence and Management of Immune-Related Adverse Events in Patients Undergoing Treatment with Immune Checkpoint Inhibitors.
Lisa A Kottschade.
Curr Oncol Rep, 2018 Mar 08; 20(3). PMID: 29511902
Review.
The Expression and Prognostic Impact of Immune Cytolytic Activity-Related Markers in Human Malignancies: A Comprehensive Meta-analysis.
Constantinos Roufas, Dimitrios Chasiotis, +3 authors, Apostolos Zaravinos.
Front Oncol, 2018 Mar 09; 8. PMID: 29515971    Free PMC article.
A Dose-escalation Study of Recombinant Human Interleukin-18 in Combination With Ofatumumab After Autologous Peripheral Blood Stem Cell Transplantation for Lymphoma.
Michael J Robertson, Christopher W Stamatkin, +3 authors, Ahmad R Safa.
J Immunother, 2018 Mar 09; 41(3). PMID: 29517616    Free PMC article.
Genotypic and phenotypic signatures to predict immune checkpoint blockade therapy response in patients with colorectal cancer.
Xianda Zhao, Audre May, Emil Lou, Subbaya Subramanian.
Transl Res, 2018 Mar 09; 196. PMID: 29518351    Free PMC article.
Review.
Checks and Balances in Autoimmune Vasculitis.
Rebeca Hid Cadena, Wayel H Abdulahad, +4 authors, Elisabeth Brouwer.
Front Immunol, 2018 Mar 10; 9. PMID: 29520282    Free PMC article.
Review.
Whole Recombinant Saccharomyces cerevisiae Yeast Expressing Ras Mutations as Treatment for Patients With Solid Tumors Bearing Ras Mutations: Results From a Phase 1 Trial.
Allen Cohn, Michael A Morse, +6 authors, Timothy C Rodell.
J Immunother, 2018 Mar 13; 41(3). PMID: 29528991    Free PMC article.
A Phase I study of the novel immunomodulatory agent PG545 (pixatimod) in subjects with advanced solid tumours.
Keith Dredge, Todd V Brennan, +9 authors, Michael Millward.
Br J Cancer, 2018 Mar 14; 118(8). PMID: 29531325    Free PMC article.
Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells.
Taigo Kato, Tatsuo Matsuda, +10 authors, Yusuke Nakamura.
Oncotarget, 2018 Mar 16; 9(13). PMID: 29541393    Free PMC article.
Modulation of Gut Microbiota: A Novel Paradigm of Enhancing the Efficacy of Programmed Death-1 and Programmed Death Ligand-1 Blockade Therapy.
Yiming Wang, Rena Ma, +2 authors, Li Zhang.
Front Immunol, 2018 Mar 21; 9. PMID: 29556232    Free PMC article.
Review.
Immunotherapy for Merkel cell carcinoma: a turning point in patient care.
Isaac S Chan, Shailender Bhatia, Howard L Kaufman, Evan J Lipson.
J Immunother Cancer, 2018 Mar 24; 6(1). PMID: 29566749    Free PMC article.
Review.
Serial Troponin for Early Detection of Nivolumab Cardiotoxicity in Advanced Non-Small Cell Lung Cancer Patients.
Matteo Sarocchi, Francesco Grossi, +12 authors, Paolo Spallarossa.
Oncologist, 2018 Mar 24; 23(8). PMID: 29567824    Free PMC article.
Inhibition of yes-associated protein down-regulates PD-L1 (CD274) expression in human malignant pleural mesothelioma.
Ping-Chih Hsu, Jinbai Miao, +9 authors, Liang You.
J Cell Mol Med, 2018 Mar 27; 22(6). PMID: 29575535    Free PMC article.
PD-L1 expression and presence of TILs in small intestinal neuroendocrine tumours.
Angela Lamarca, Daisuke Nonaka, +10 authors, Juan W Valle.
Oncotarget, 2018 Mar 31; 9(19). PMID: 29599916    Free PMC article.
Immune-related endocrine disorders in novel Immune checkpoint inhibition therapy.
Le Min.
Genes Dis, 2016 Dec 01; 3(4). PMID: 29623291    Free PMC article.
The IDH1 Mutation-Induced Oncometabolite, 2-Hydroxyglutarate, May Affect DNA Methylation and Expression of PD-L1 in Gliomas.
Luyan Mu, Yu Long, +12 authors, Jianping Huang.
Front Mol Neurosci, 2018 Apr 13; 11. PMID: 29643764    Free PMC article.
Immune checkpoint pathways in non-small cell lung cancer.
Young Kwang Chae, Ayush Arya, +4 authors, Francis J Giles.
Ann Transl Med, 2018 Apr 19; 6(5). PMID: 29666811    Free PMC article.
Review.
Expression of immune checkpoint regulators, cytotoxic T lymphocyte antigen 4 (CTLA-4) and programmed death-ligand 1 (PD-L1), in female breast carcinomas.
Ari Kassardjian, Peter I Shintaku, Neda A Moatamed.
PLoS One, 2018 Apr 20; 13(4). PMID: 29672601    Free PMC article.
T Cell Calcium Signaling Regulation by the Co-Receptor CD5.
Claudia M Tellez Freitas, Deborah K Johnson, K Scott Weber.
Int J Mol Sci, 2018 Apr 28; 19(5). PMID: 29701673    Free PMC article.
Review.
The Role of Epstein-Barr Virus in Cervical Cancer: A Brief Update.
Semir Vranic, Farhan Sachal Cyprian, Saghir Akhtar, Ala-Eddin Al Moustafa.
Front Oncol, 2018 May 03; 8. PMID: 29719817    Free PMC article.
Review.
Complimentary mechanisms of dual checkpoint blockade expand unique T-cell repertoires and activate adaptive anti-tumor immunity in triple-negative breast tumors.
Erika J Crosby, Junping Wei, +10 authors, Zachary C Hartman.
Oncoimmunology, 2018 May 04; 7(5). PMID: 29721371    Free PMC article.
M7824, a novel bifunctional anti-PD-L1/TGFβ Trap fusion protein, promotes anti-tumor efficacy as monotherapy and in combination with vaccine.
Karin M Knudson, Kristin C Hicks, +3 authors, Sofia R Gameiro.
Oncoimmunology, 2018 May 04; 7(5). PMID: 29721396    Free PMC article.
Highly Cited.
Modeling combination therapy for breast cancer with BET and immune checkpoint inhibitors.
Xiulan Lai, Andrew Stiff, +3 authors, Avner Friedman.
Proc Natl Acad Sci U S A, 2018 May 08; 115(21). PMID: 29735668    Free PMC article.
Mutation load estimation model as a predictor of the response to cancer immunotherapy.
Guan-Yi Lyu, Yu-Hsuan Yeh, Yi-Chen Yeh, Yu-Chao Wang.
NPJ Genom Med, 2018 May 08; 3. PMID: 29736260    Free PMC article.
Pathway perturbations in signaling networks: Linking genotype to phenotype.
Yongsheng Li, Daniel J McGrail, +3 authors, Nidhi Sahni.
Semin Cell Dev Biol, 2018 May 09; 99. PMID: 29738884    Free PMC article.
Review.
Mechanisms of immune evasion in breast cancer.
Joshua P Bates, Roshanak Derakhshandeh, Laundette Jones, Tonya J Webb.
BMC Cancer, 2018 May 13; 18(1). PMID: 29751789    Free PMC article.
Review.
Significance and implications of FDA approval of pembrolizumab for biomarker-defined disease.
Michael M Boyiadzis, John M Kirkwood, +3 authors, James L Gulley.
J Immunother Cancer, 2018 May 15; 6(1). PMID: 29754585    Free PMC article.
Highly Cited. Review.
Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy.
Bo Zhu, Liming Tang, +15 authors, Peng Cao.
Oncogene, 2018 May 23; 37(36). PMID: 29786078
Autoimmune Granulomatous Inflammation of Lacrimal Glands and Axonal Neuritis Following Treatment With Ipilimumab and Radiation Therapy.
Ecaterina Ileana Dumbrava, Veronica Smith, +3 authors, Apostolia M Tsimberidou.
J Immunother, 2018 May 23; 41(7). PMID: 29787423    Free PMC article.
Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes.
Kevin C Osum, Adam L Burrack, +8 authors, Brian T Fife.
Sci Rep, 2018 May 31; 8(1). PMID: 29844327    Free PMC article.
Diagnostic value of peripheral blood immune profiling in colorectal cancer.
Joungbum Choi, Hyung Gun Maeng, +12 authors, Jong Kyun Lee.
Ann Surg Treat Res, 2018 Jun 02; 94(6). PMID: 29854709    Free PMC article.
Clinicopathological analysis and prognostic significance of programmed cell death-ligand 1 protein and mRNA expression in non-small cell lung cancer.
Hyojin Kim, Hyun Jung Kwon, +3 authors, Jin-Haeng Chung.
PLoS One, 2018 Jun 02; 13(6). PMID: 29856861    Free PMC article.
Computational immune profiling in lung adenocarcinoma reveals reproducible prognostic associations with implications for immunotherapy.
Frederick S Varn, Laura J Tafe, Christopher I Amos, Chao Cheng.
Oncoimmunology, 2018 Jun 07; 7(6). PMID: 29872556    Free PMC article.
A mathematical modelling tool for unravelling the antibody-mediated effects on CTLA-4 interactions.
Aravindhan Ganesan, Theinmozhi Arulraj, Tahir Choulli, Khaled H Barakat.
BMC Med Inform Decis Mak, 2018 Jun 13; 18(1). PMID: 29890992    Free PMC article.
Advanced Care Provider and Nursing Approach to Assessment and Management of Immunotherapy-Related Dermatologic Adverse Events.
Kathryn Ciccolini, Anna Skripnik Lucas, Alyona Weinstein, Mario Lacouture.
J Adv Pract Oncol, 2017 Mar 01; 8(2). PMID: 29900022    Free PMC article.
Review.
Large-scale database mining reveals hidden trends and future directions for cancer immunotherapy.
Jakob Nikolas Kather, Anna Sophie Berghoff, +6 authors, Niels Halama.
Oncoimmunology, 2018 Jun 15; 7(7). PMID: 29900054    Free PMC article.
The Role of Immune Checkpoint Inhibitors in Classical Hodgkin Lymphoma.
Nicholas Meti, Khashayar Esfahani, Nathalie A Johnson.
Cancers (Basel), 2018 Jun 20; 10(6). PMID: 29914088    Free PMC article.
Review.
Pediatric Cancer Immunotherapy: Opportunities and Challenges.
Mary Frances Wedekind, Nicholas L Denton, Chun-Yu Chen, Timothy P Cripe.
Paediatr Drugs, 2018 Jun 28; 20(5). PMID: 29948928    Free PMC article.
Review.
Programmed cell death ligand-1 protein expression and CD274/PD-L1 gene amplification in colorectal cancer: Implications for prognosis.
Kyu Sang Lee, Bo Hyung Kim, +4 authors, Eun Shin.
Cancer Sci, 2018 Jun 28; 109(9). PMID: 29949671    Free PMC article.
CD8+ T-Cell Density Imaging with 64Cu-Labeled Cys-Diabody Informs Immunotherapy Protocols.
Jai Woong Seo, Richard Tavaré, +7 authors, Katherine W Ferrara.
Clin Cancer Res, 2018 Jul 04; 24(20). PMID: 29967252    Free PMC article.
Targeting Macrophages as a Potential Therapeutic Intervention: Impact on Inflammatory Diseases and Cancer.
Mirco Ponzoni, Fabio Pastorino, +2 authors, Chiara Brignole.
Int J Mol Sci, 2018 Jul 06; 19(7). PMID: 29973487    Free PMC article.
Review.
Systemically Administered Sindbis Virus in Combination with Immune Checkpoint Blockade Induces Curative Anti-tumor Immunity.
Iris Scherwitzl, Alicia Hurtado, +3 authors, Daniel Meruelo.
Mol Ther Oncolytics, 2018 Jul 11; 9. PMID: 29988525    Free PMC article.
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.
Jia-Ren Lin, Benjamin Izar, +5 authors, Peter K Sorger.
Elife, 2018 Jul 12; 7. PMID: 29993362    Free PMC article.
Highly Cited.
The influence of radiation in the context of developing combination immunotherapies in cancer.
Jamie Honeychurch, Timothy M Illidge.
Ther Adv Vaccines Immunother, 2018 Jul 13; 5(6). PMID: 29998216    Free PMC article.
Review.
Microbial biomarkers for immune checkpoint blockade therapy against cancer.
Keishi Adachi, Koji Tamada.
J Gastroenterol, 2018 Jul 14; 53(9). PMID: 30003334    Free PMC article.
Review.
Autoantibodies as Potential Biomarkers in Breast Cancer.
Jingyi Qiu, Bailey Keyser, Zuan-Tao Lin, Tianfu Wu.
Biosensors (Basel), 2018 Jul 18; 8(3). PMID: 30011807    Free PMC article.
Review.
Avelumab inducing hypothyroidism and hypoadrenalism: A case report and review of literature.
Kashif Aziz, Amir Shahbaz, Muhammad Umair, Isaac Sachmechi.
EXCLI J, 2018 Jul 24; 17. PMID: 30034316    Free PMC article.
Phytosomal curcumin causes natural killer cell-dependent repolarization of glioblastoma (GBM) tumor-associated microglia/macrophages and elimination of GBM and GBM stem cells.
Sumit Mukherjee, Angela Fried, +4 authors, Probal Banerjee.
J Exp Clin Cancer Res, 2018 Jul 26; 37(1). PMID: 30041669    Free PMC article.
Consistency of tumor and immune cell programmed cell death ligand-1 expression within and between tumor blocks using the VENTANA SP263 assay.
Paul Scorer, Marietta Scott, +4 authors, Jill Walker.
Diagn Pathol, 2018 Jul 26; 13(1). PMID: 30041679    Free PMC article.
Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltration.
Ayman Oweida, Mohammad K Hararah, +14 authors, Sana D Karam.
Clin Cancer Res, 2018 Jul 26; 24(21). PMID: 30042205    Free PMC article.
Highly Cited.
MicroRNAs as Immunotherapy Targets for Treating Gastroenterological Cancers.
Yixin Yang, Christopher Alderman, +2 authors, Wei Wang.
Can J Gastroenterol Hepatol, 2018 Jul 27; 2018. PMID: 30046565    Free PMC article.
Review.
Nivolumab-induced cold agglutinin syndrome successfully treated with rituximab.
Merve Hasanov, Sergej N Konoplev, Cristhiam M Rojas Hernandez.
Blood Adv, 2018 Aug 04; 2(15). PMID: 30072374    Free PMC article.
Can IDO activity predict primary resistance to anti-PD-1 treatment in NSCLC?
Andrea Botticelli, Bruna Cerbelli, +7 authors, Paolo Marchetti.
J Transl Med, 2018 Aug 08; 16(1). PMID: 30081936    Free PMC article.
DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer.
Varun Sasidharan Nair, Salman M Toor, +2 authors, Eyad Elkord.
Clin Epigenetics, 2018 Aug 08; 10(1). PMID: 30081950    Free PMC article.
Targeting Interleukin-6 (IL-6) Sensitizes Anti-PD-L1 Treatment in a Colorectal Cancer Preclinical Model.
Jibin Li, Jian Xu, +3 authors, Rui Zhang.
Med Sci Monit, 2018 Aug 09; 24. PMID: 30087314    Free PMC article.
Detection of identical T cell clones in peritumoral pleural effusion and pneumonitis lesions in a cancer patient during immune-checkpoint blockade.
Kentaro Tanaka, Toyoshi Yanagihara, +15 authors, Isamu Okamoto.
Oncotarget, 2018 Aug 11; 9(55). PMID: 30093971    Free PMC article.
Complex interplay between tumor microenvironment and cancer therapy.
Minhong Shen, Yibin Kang.
Front Med, 2018 Aug 12; 12(4). PMID: 30097962
Review.
Cancer Cell-Intrinsic PD-1 and Implications in Combinatorial Immunotherapy.
Han Yao, Huanbin Wang, +2 authors, Jie Xu.
Front Immunol, 2018 Aug 15; 9. PMID: 30105035    Free PMC article.
Review.
Distinct Changes of BTLA and HVEM Expressions in Circulating CD4+ and CD8+ T Cells in Hepatocellular Carcinoma Patients.
Jiayu Liu, Jiaqian Li, +2 authors, Qiyi Zhao.
J Immunol Res, 2018 Aug 18; 2018. PMID: 30116751    Free PMC article.
Effective nivolumab sequential thoracic radiotherapy in elderly patients with advanced squamous cell lung cancer: did radiation therapy play a role? A case report.
Grazia Lazzari, Angela Terlizzi, +4 authors, Giovanni Silvano.
Onco Targets Ther, 2018 Aug 21; 11. PMID: 30122953    Free PMC article.
Sunitinib and Sorafenib Modulating Antitumor Immunity in Hepatocellular Cancer.
Dai Liu, Xiaoqiang Qi, +5 authors, Guangfu Li.
J Immunol Res Ther, 2018 Aug 21; 3(1). PMID: 30123861    Free PMC article.
Beyond microsatellite testing: assessment of tumor mutational burden identifies subsets of colorectal cancer who may respond to immune checkpoint inhibition.
David A Fabrizio, Thomas J George, +13 authors, Samuel J Klempner.
J Gastrointest Oncol, 2018 Aug 29; 9(4). PMID: 30151257    Free PMC article.
Highly Cited.
Characterization of the Neuroendocrine Tumor Immune Microenvironment.
Annacarolina da Silva, Michaela Bowden, +10 authors, Matthew H Kulke.
Pancreas, 2018 Aug 29; 47(9). PMID: 30153220    Free PMC article.
Immune Checkpoint Inhibitors: Toward New Paradigms in Renal Cell Carcinoma.
Ronan Flippot, Bernard Escudier, Laurence Albiges.
Drugs, 2018 Sep 07; 78(14). PMID: 30187355
Review.
Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis.
William P D Hendricks, Victoria Zismann, +24 authors, Jeffrey M Trent.
PLoS Genet, 2018 Sep 07; 14(9). PMID: 30188888    Free PMC article.
Targeting immune checkpoints in melanoma: an update.
Rodrigo R Munhoz, Alejandro Falcón González, Vanessa A Reed, Michael A Postow.
Melanoma Manag, 2015 Nov 01; 2(4). PMID: 30190862    Free PMC article.
Review.
New insights in melanoma biomarkers: long-noncoding RNAs.
Ricardo Moreno-Traspas, Igor Vujic, Martina Sanlorenzo, Susana Ortiz-Urda.
Melanoma Manag, 2016 Sep 01; 3(3). PMID: 30190889    Free PMC article.
Review.
Gastrointestinal adverse events with combination of checkpoint inhibitors in advanced melanoma: a systematic review.
Elizabeth S Mearns, Jill A Bell, +4 authors, Ignacio Garcia-Ribas.
Melanoma Manag, 2018 Sep 08; 5(1). PMID: 30190927    Free PMC article.
Review.
Immune checkpoint inhibitors for hepatocellular carcinoma.
Christopher E Jensen, Arturo Loaiza-Bonilla, Paula A Bonilla-Reyes.
Hepat Oncol, 2016 Aug 01; 3(3). PMID: 30191042    Free PMC article.
Review.
Complete Clinical Remission of Stage IV Triple-Negative Breast Cancer Lung Metastasis Administering Low-Dose Immune Checkpoint Blockade in Combination With Hyperthermia and Interleukin-2.
Ralf Kleef, Ralph Moss, +3 authors, Tibor Bakacs.
Integr Cancer Ther, 2018 Sep 09; 17(4). PMID: 30193538    Free PMC article.
Multifactorial regulators of tumor programmed death-ligand 1 (PD-L1) response.
R Dixon Dorand, Agne Petrosiute, Alex Y Huang.
Transl Cancer Res, 2018 Sep 11; 6(Suppl 9). PMID: 30197875    Free PMC article.
Alpha-fetoprotein (AFP) as tumor marker in a patient with urothelial cancer with exceptional response to anti-PD-1 therapy and an escape lesion mimic.
Johannes C Melms, Rohit Thummalapalli, +4 authors, Benjamin Izar.
J Immunother Cancer, 2018 Sep 14; 6(1). PMID: 30208947    Free PMC article.
Roles of intestinal microbiota in response to cancer immunotherapy.
Jing Cong, Xiaochun Zhang.
Eur J Clin Microbiol Infect Dis, 2018 Sep 14; 37(12). PMID: 30209679
Review.
Functional Proteomics and Deep Network Interrogation Reveal a Complex Mechanism of Action of Midostaurin in Lung Cancer Cells.
Claudia Ctortecka, Vinayak Palve, +9 authors, Uwe Rix.
Mol Cell Proteomics, 2018 Sep 16; 17(12). PMID: 30217950    Free PMC article.
Combination of dual mTORC1/2 inhibition and immune-checkpoint blockade potentiates anti-tumour immunity.
Sophie Langdon, Adina Hughes, +8 authors, Charles Sinclair.
Oncoimmunology, 2018 Sep 18; 7(8). PMID: 30221055    Free PMC article.
Use of checkpoint inhibitors in liver transplant recipients.
Stefan Munker, Enrico N De Toni.
United European Gastroenterol J, 2018 Sep 20; 6(7). PMID: 30228883    Free PMC article.
Review.
Lessons From the Development of the Immune Checkpoint Inhibitors in Oncology.
Denis L Jardim, Débora de Melo Gagliato, Razelle Kurzrock.
Integr Cancer Ther, 2018 Sep 20; 17(4). PMID: 30229677    Free PMC article.
Review.
Not All Immune Checkpoints Are Created Equal.
Annika De Sousa Linhares, Judith Leitner, Katharina Grabmeier-Pfistershammer, Peter Steinberger.
Front Immunol, 2018 Sep 21; 9. PMID: 30233564    Free PMC article.
Highly Cited. Review.
New opportunities for nanoparticles in cancer immunotherapy.
Wooram Park, Young-Jae Heo, Dong Keun Han.
Biomater Res, 2018 Oct 03; 22. PMID: 30275967    Free PMC article.
Review.
Effect of Differences in Metabolic Activity of Melanoma Models on Response to Lonidamine plus Doxorubicin.
Kavindra Nath, Jeffrey Roman, +10 authors, Jerry D Glickson.
Sci Rep, 2018 Oct 04; 8(1). PMID: 30279592    Free PMC article.
TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy.
Padmini Jayaraman, Falguni Parikh, +13 authors, Andrew G Sikora.
Oncoimmunology, 2018 Oct 06; 7(10). PMID: 30288358    Free PMC article.
Prognostic Factors for Checkpoint Inhibitor Based Immunotherapy: An Update With New Evidences.
Xinyu Yan, Shouyue Zhang, +3 authors, Heng Xu.
Front Pharmacol, 2018 Oct 09; 9. PMID: 30294272    Free PMC article.
Review.
Expression of the Immune Checkpoint Modulator OX40 in Acute Lymphoblastic Leukemia Is Associated with BCR-ABL Positivity.
Kathrin Rothfelder, Ilona Hagelstein, +6 authors, Daniela Dörfel.
Neoplasia, 2018 Oct 10; 20(11). PMID: 30300827    Free PMC article.
Checkpoint Blockade Reverses Anergy in IL-13Rα2 Humanized scFv-Based CAR T Cells to Treat Murine and Canine Gliomas.
Yibo Yin, Alina C Boesteanu, +20 authors, Laura A Johnson.
Mol Ther Oncolytics, 2018 Oct 12; 11. PMID: 30306125    Free PMC article.
Stimulation of natural killer cells with rhCD137 ligand enhances tumor-targeting antibody efficacy in gastric cancer.
Toshihiro Misumi, Kazuaki Tanabe, Nobuaki Fujikuni, Hideki Ohdan.
PLoS One, 2018 Oct 16; 13(10). PMID: 30321186    Free PMC article.
Anti-PD-1/PD-L1 Antibody Therapy for Pretreated Advanced or Metastatic Nonsmall Cell Lung Carcinomas and the Correlation between PD-L1 Expression and Treatment Effectiveness: An Update Meta-Analysis of Randomized Clinical Trials.
Qiuling Zhao, Ruixiang Xie, +2 authors, Xiuhua Weng.
Biomed Res Int, 2018 Oct 23; 2018. PMID: 30345301    Free PMC article.
Systematic Review.
The DNA damage response in immunotherapy and radiation.
Robert M Samstein, Nadeem Riaz.
Adv Radiat Oncol, 2018 Oct 30; 3(4). PMID: 30370352    Free PMC article.
Review.
The Optimal Radiation Dose to Induce Robust Systemic Anti-Tumor Immunity.
Jan Poleszczuk, Heiko Enderling.
Int J Mol Sci, 2018 Nov 02; 19(11). PMID: 30380596    Free PMC article.
Sitravatinib potentiates immune checkpoint blockade in refractory cancer models.
Wenting Du, Huocong Huang, Noah Sorrelle, Rolf A Brekken.
JCI Insight, 2018 Nov 06; 3(21). PMID: 30385724    Free PMC article.
The Application of Nanoparticle-Based Drug Delivery Systems in Checkpoint Blockade Cancer Immunotherapy.
Huan Zhao, Yuanqi Li, Dan Wei, Hongrong Luo.
J Immunol Res, 2018 Nov 09; 2018. PMID: 30406152    Free PMC article.
Review.
Polyclonal Rabbit Anti-Cancer-Associated Fibroblasts Globulins Induce Cancer Cells Apoptosis and Inhibit Tumor Growth.
Xiuying Li, Fengchang Huang, Xiaoyu Xu, Shuenqin Hu.
Int J Biol Sci, 2018 Nov 13; 14(12). PMID: 30416376    Free PMC article.
The efficacy and safety of immune checkpoint inhibitor combination therapy in lung cancer: a systematic review and meta-analysis.
Min Peng, Xing Li, +3 authors, Qi Bin Song.
Onco Targets Ther, 2018 Nov 15; 11. PMID: 30425525    Free PMC article.
Review.
HGF/MET and the Immune System: Relevance for Cancer Immunotherapy.
Federica Papaccio, Carminia Maria Della Corte, +5 authors, Floriana Morgillo.
Int J Mol Sci, 2018 Nov 18; 19(11). PMID: 30441809    Free PMC article.
Review.
Cardiovascular toxicities associated with immune checkpoint inhibitors: an observational, retrospective, pharmacovigilance study.
Joe-Elie Salem, Ali Manouchehri, +10 authors, Javid J Moslehi.
Lancet Oncol, 2018 Nov 18; 19(12). PMID: 30442497    Free PMC article.
Highly Cited.
Combination therapy for metastatic melanoma: a pharmacist's role, drug interactions & complementary alternative therapies.
Gabriel Gazzé.
Melanoma Manag, 2018 Nov 22; 5(2). PMID: 30459938    Free PMC article.
Review.
Immune therapy in sepsis: Are we ready to try again?
Roger Davies, Kieran O'Dea, Anthony Gordon.
J Intensive Care Soc, 2018 Dec 06; 19(4). PMID: 30515242    Free PMC article.
Review.
The Clinical and Biomarker Association of Programmed Death Ligand 1 and its Spatial Heterogeneous Expression in Colorectal Cancer.
Xiao-Li Wei, Qi-Nian Wu, +8 authors, Rui-Hua Xu.
J Cancer, 2018 Dec 07; 9(23). PMID: 30519336    Free PMC article.
CD27 stimulation unveils the efficacy of linked class I/II peptide vaccines in poorly immunogenic tumors by orchestrating a coordinated CD4/CD8 T cell response.
Katherine A Riccione, Li-Zhen He, +10 authors, John H Sampson.
Oncoimmunology, 2018 Dec 14; 7(12). PMID: 30524899    Free PMC article.
Modulation of immune checkpoint molecule expression in mantle cell lymphoma.
Bonnie K Harrington, Esther Wheeler, +12 authors, Lapo Alinari.
Leuk Lymphoma, 2019 Mar 02; 60(10). PMID: 30821551    Free PMC article.
Rheumatic complications in cancer patients treated with immune checkpoint inhibitors.
Kyung-Ann Lee, Hae-Rim Kim, So Young Yoon.
Korean J Intern Med, 2019 Apr 25; 34(6). PMID: 31014065    Free PMC article.
Review.
Ku80 promotes melanoma growth and regulates antitumor effect of melatonin by targeting HIF1-α dependent PDK-1 signaling pathway.
Tianze Liu, Lizi Jin, +18 authors, Wuguo Deng.
Redox Biol, 2019 Apr 27; 25. PMID: 31023624    Free PMC article.
Mechanisms of immunogenicity in colorectal cancer.
T O Sillo, A D Beggs, D G Morton, G Middleton.
Br J Surg, 2019 Jun 20; 106(10). PMID: 31216061    Free PMC article.
Review.
The immune microenvironment and expression of PD-L1, PD-1, PRAME and MHC I in salivary duct carcinoma.
Bin Xu, Achim A Jungbluth, +8 authors, Nora Katabi.
Histopathology, 2019 Jun 27; 75(5). PMID: 31237963    Free PMC article.
Anticancer Immunotherapy by MFAP5 Blockade Inhibits Fibrosis and Enhances Chemosensitivity in Ovarian and Pancreatic Cancer.
Tsz-Lun Yeung, Cecilia S Leung, +6 authors, Samuel C Mok.
Clin Cancer Res, 2019 Jul 25; 25(21). PMID: 31332047    Free PMC article.
Novel Delivery Systems for Checkpoint Inhibitors.
Purushottam Lamichhane, Rahul Deshmukh, +8 authors, Narottam Lamichhane.
Medicines (Basel), 2019 Aug 03; 6(3). PMID: 31373327    Free PMC article.
Review.
Role of immune checkpoint inhibitor-based therapies for metastatic renal cell carcinoma in the first-line setting: A Bayesian network analysis.
Junpeng Wang, Xin Li, +6 authors, Tianzhong Yan.
EBioMedicine, 2019 Aug 24; 47. PMID: 31439476    Free PMC article.
Localized Treatment with Oncolytic Adenovirus Delta-24-RGDOX Induces Systemic Immunity against Disseminated Subcutaneous and Intracranial Melanomas.
Hong Jiang, Dong Ho Shin, +10 authors, Candelaria Gomez-Manzano.
Clin Cancer Res, 2019 Aug 29; 25(22). PMID: 31455679    Free PMC article.
Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges.
Muhammad Zaeem Noman, Meriem Hasmim, +5 authors, Bassam Janji.
Cells, 2019 Sep 22; 8(9). PMID: 31540045    Free PMC article.
Review.
Conceptual Development of Immunotherapeutic Approaches to Gastrointestinal Cancer.
Bilikis Aderonke Abolarinwa, Ridwan Babatunde Ibrahim, Yen-Hua Huang.
Int J Mol Sci, 2019 Sep 22; 20(18). PMID: 31540435    Free PMC article.
Review.
The Evolving Landscape of Biomarkers for Anti-PD-1 or Anti-PD-L1 Therapy.
Antje Tunger, Ulrich Sommer, +7 authors, Marc Schmitz.
J Clin Med, 2019 Sep 29; 8(10). PMID: 31557787    Free PMC article.
Review.
Risk factors for immune-related adverse events associated with anti-PD-1 pembrolizumab.
Yeonghee Eun, In Young Kim, +5 authors, Jaejoon Lee.
Sci Rep, 2019 Oct 03; 9(1). PMID: 31575933    Free PMC article.
The Course of Immune Stimulation by Photodynamic Therapy: Bridging Fundamentals of Photochemically Induced Immunogenic Cell Death to the Enrichment of T-Cell Repertoire.
Shubhankar Nath, Girgis Obaid, Tayyaba Hasan.
Photochem Photobiol, 2019 Oct 12; 95(6). PMID: 31602649    Free PMC article.
Review.
New Horizons in KRAS-Mutant Lung Cancer: Dawn After Darkness.
Haitang Yang, Shun-Qing Liang, Ralph A Schmid, Ren-Wang Peng.
Front Oncol, 2019 Oct 16; 9. PMID: 31612108    Free PMC article.
Review.
Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response.
Bridget P Keenan, Lawrence Fong, Robin K Kelley.
J Immunother Cancer, 2019 Oct 20; 7(1). PMID: 31627733    Free PMC article.
Review.
Efficacy and tolerability of anti-programmed death-ligand 1 (PD-L1) antibody (Avelumab) treatment in advanced thymoma.
Arun Rajan, Christopher R Heery, +19 authors, James L Gulley.
J Immunother Cancer, 2019 Oct 23; 7(1). PMID: 31639039    Free PMC article.
[Management of Rheumatic Adverse Events Related to Immune Checkpoint Inhibitors].
Jiaxin Zhou, Qian Wang, +8 authors, Li Zhang.
Zhongguo Fei Ai Za Zhi, 2019 Oct 28; 22(10). PMID: 31650952    Free PMC article.
Review.
Present Scenario of Bioconjugates in Cancer Therapy: A Review.
Aishani Wadhawan, Mary Chatterjee, Gurpal Singh.
Int J Mol Sci, 2019 Oct 28; 20(21). PMID: 31652668    Free PMC article.
Review.
Safety and Efficacy of Therapeutic Cancer Vaccines Alone or in Combination With Immune Checkpoint Inhibitors in Cancer Treatment.
Jing Zhao, Ye Chen, Zhen-Yu Ding, Ji-Yan Liu.
Front Pharmacol, 2019 Nov 05; 10. PMID: 31680963    Free PMC article.
Review.
Endocrine toxicity of immune checkpoint inhibitors: a real-world study leveraging US Food and Drug Administration adverse events reporting system.
Yinghong Zhai, Xiaofei Ye, +4 authors, Jia He.
J Immunother Cancer, 2019 Nov 07; 7(1). PMID: 31694698    Free PMC article.
Nanoparticle Delivery of Immunostimulatory Agents for Cancer Immunotherapy.
Jia Zhuang, Maya Holay, +3 authors, Liangfang Zhang.
Theranostics, 2019 Nov 07; 9(25). PMID: 31695803    Free PMC article.
Review.
Integrin αvβ3-targeted radionuclide therapy combined with immune checkpoint blockade immunotherapy synergistically enhances anti-tumor efficacy.
Haojun Chen, Liang Zhao, +9 authors, Xiaoyuan Chen.
Theranostics, 2019 Nov 07; 9(25). PMID: 31695808    Free PMC article.
Genetic Biomarkers For Hepatocellular Carcinoma In The Era Of Precision Medicine.
Jingxian Duan, Yuling Wu, +7 authors, Shifu Chen.
J Hepatocell Carcinoma, 2019 Nov 07; 6. PMID: 31696097    Free PMC article.
Review.
Budesonide treatment for microscopic colitis from immune checkpoint inhibitors.
Michael S Hughes, Gabriel E Molina, +5 authors, Michael Dougan.
J Immunother Cancer, 2019 Nov 09; 7(1). PMID: 31699151    Free PMC article.
Immune Checkpoint Inhibition in Hodgkin Lymphoma.
Ryan H Moy, Anas Younes.
Hemasphere, 2018 Feb 16; 2(1). PMID: 31723749    Free PMC article.
Review.
Does selected immunological panel possess the value of predicting the prognosis of early-stage resectable non-small cell lung cancer?
Xiaoshen Zhang, Yayi He, +6 authors, Caicun Zhou.
Transl Lung Cancer Res, 2019 Nov 19; 8(5). PMID: 31737493    Free PMC article.
Combination of PD-L1 expression and NLR as prognostic marker in patients with surgically resected non-small cell lung cancer.
Xinyue Wang, Lianjing Cao, +3 authors, Richeng Jiang.
J Cancer, 2019 Nov 30; 10(26). PMID: 31777599    Free PMC article.
Prognostic factors and a new scoring system for survival of patients irradiated for bone metastases.
Dirk Rades, Rapha Haus, Steven E Schild, Stefan Janssen.
BMC Cancer, 2019 Nov 30; 19(1). PMID: 31779595    Free PMC article.
Immunotherapy response evaluation with magnetic resonance elastography (MRE) in advanced HCC.
Aliya Qayyum, Ken-Pin Hwang, +13 authors, Ahmed O Kaseb.
J Immunother Cancer, 2019 Nov 30; 7(1). PMID: 31779702    Free PMC article.
A subset of patients with MSS/MSI-low-colorectal cancer showed increased CD8(+) TILs together with up-regulated IFN-γ.
Tomohiro Kikuchi, Kosaku Mimura, +12 authors, Koji Kono.
Oncol Lett, 2019 Dec 04; 18(6). PMID: 31788072    Free PMC article.
Comparative Approach to the Temporo-Spatial Organization of the Tumor Microenvironment.
Kendall L Langsten, Jong Hyuk Kim, +2 authors, Jaime F Modiano.
Front Oncol, 2019 Dec 04; 9. PMID: 31788448    Free PMC article.
Review.
MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.
Hui Li, Chia-Wei Li, +16 authors, Mien-Chie Hung.
Gastroenterology, 2019 Feb 04; 156(6). PMID: 30711629    Free PMC article.
Highly Cited.
Pancytopenia And Limbic Encephalopathy Complicating Immunotherapy For Clear Cell Endometrial Cancer With Microsatellite Instability-High (MSI-H).
Aladdin Kanbour, Kakil Ibrahim Rasul, +7 authors, Nabil Elhadi Omar.
Onco Targets Ther, 2019 Dec 11; 12. PMID: 31819493    Free PMC article.
Immune checkpoint inhibitors therapy in older patients (≥ 70 years) with metastatic melanoma: a multicentre study.
Bożena Cybulska-Stopa, Iwona Ługowska, +12 authors, Piotr Rutkowski.
Postepy Dermatol Alergol, 2019 Dec 17; 36(5). PMID: 31839773    Free PMC article.
Proteolytic chemokine cleavage as a regulator of lymphocytic infiltration in solid tumors.
Holger Bronger, Viktor Magdolen, Peter Goettig, Tobias Dreyer.
Cancer Metastasis Rev, 2019 Sep 05; 38(3). PMID: 31482487    Free PMC article.
Review.
Lymphocyte-activation gene 3 (LAG3): The next immune checkpoint receptor.
Elisa Ruffo, Richard C Wu, +2 authors, Dario A A Vignali.
Semin Immunol, 2019 Oct 13; 42. PMID: 31604537    Free PMC article.
Review.
Overview of Immune Checkpoint Inhibitors Therapy for Hepatocellular Carcinoma, and The ITA.LI.CA Cohort Derived Estimate of Amenability Rate to Immune Checkpoint Inhibitors in Clinical Practice.
Edoardo G Giannini, Andrea Aglitti, +15 authors, Associazione Italiana per lo Studio del Fegato (AISF) HCC Special Interest Group.
Cancers (Basel), 2019 Nov 02; 11(11). PMID: 31671581    Free PMC article.
Review.
The Prognostic Role of CD8+ T Lymphocytes in Childhood Adrenocortical Carcinomas Compared to Ki-67, PD-1, PD-L1, and the Weiss Score.
Ivy Zortéa S Parise, Guilherme A Parise, +22 authors, Bonald C Figueiredo.
Cancers (Basel), 2019 Nov 07; 11(11). PMID: 31694270    Free PMC article.
The Lung Immune Prognostic Index Discriminates Survival Outcomes in Patients with Solid Tumors Treated with Immune Checkpoint Inhibitors.
Daniel E Meyers, Igor Stukalin, +9 authors, Don G Morris.
Cancers (Basel), 2019 Nov 07; 11(11). PMID: 31684111    Free PMC article.
Personalized medicine in cardio-oncology: the role of induced pluripotent stem cell.
Nazish Sayed, Mohamed Ameen, Joseph C Wu.
Cardiovasc Res, 2019 Feb 16; 115(5). PMID: 30768178    Free PMC article.
Review.
Fasting and cancer: molecular mechanisms and clinical application.
Alessio Nencioni, Irene Caffa, Salvatore Cortellino, Valter D Longo.
Nat Rev Cancer, 2018 Oct 18; 18(11). PMID: 30327499    Free PMC article.
Highly Cited. Review.
Microparticles from tumors exposed to radiation promote immune evasion in part by PD-L1.
Michael Timaner, Ruslana Kotsofruk, +10 authors, Yuval Shaked.
Oncogene, 2019 Aug 31; 39(1). PMID: 31467431    Free PMC article.
Immune Activation in Mismatch Repair-Deficient Carcinogenesis: More Than Just Mutational Rate.
Jason A Willis, Laura Reyes-Uribe, +2 authors, Eduardo Vilar.
Clin Cancer Res, 2019 Aug 07; 26(1). PMID: 31383734    Free PMC article.
Review.
Management of immune checkpoint inhibitor-related rheumatic adverse events.
Jiaxin Zhou, Hanping Wang, +8 authors, Li Zhang.
Thorac Cancer, 2019 Nov 26; 11(1). PMID: 31762209    Free PMC article.
Systematic Review.
Personal response to immune checkpoint inhibitors of patients with advanced melanoma explained by a computational model of cellular immunity, tumor growth, and drug.
D Perlstein, O Shlagman, +4 authors, Z Agur.
PLoS One, 2019 Dec 27; 14(12). PMID: 31877168    Free PMC article.
Severe Immune-Related Pneumonitis With PD-1 Inhibitor After Progression on Previous PD-L1 Inhibitor in Small Cell Lung Cancer: A Case Report and Review of the Literature.
Xiuju Liang, Yaping Guan, +4 authors, Jun Wang.
Front Oncol, 2020 Jan 11; 9. PMID: 31921686    Free PMC article.
Current and Future Treatment Strategies for Rhabdomyosarcoma.
Celine Chen, Heathcliff Dorado Garcia, Monika Scheer, Anton G Henssen.
Front Oncol, 2020 Jan 11; 9. PMID: 31921698    Free PMC article.
Review.
Mechanistic Understanding of Curcumin's Therapeutic Effects in Lung Cancer.
Wan Nur Baitty Wan Mohd Tajuddin, Nordin H Lajis, +2 authors, Rakesh Naidu.
Nutrients, 2019 Dec 11; 11(12). PMID: 31817718    Free PMC article.
Review.
The Cross Talk between Cancer Stem Cells/Cancer Initiating Cells and Tumor Microenvironment: The Missing Piece of the Puzzle for the Efficient Targeting of these Cells with Immunotherapy.
Shilpa Ravindran, Saad Rasool, Cristina Maccalli.
Cancer Microenviron, 2019 Nov 24; 12(2-3). PMID: 31758404    Free PMC article.
PD-L1 assessment in urothelial carcinoma: a practical approach.
Markus Eckstein, Alessia Cimadamore, +5 authors, Thomas Gevaert.
Ann Transl Med, 2020 Jan 14; 7(22). PMID: 31930091    Free PMC article.
Review.
Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy.
Victoria Klepsch, Maria Pommermayr, +3 authors, Gottfried Baier.
Cell Commun Signal, 2020 Jan 16; 18(1). PMID: 31937317    Free PMC article.
Amplifying Outcomes: Checkpoint Inhibitor Combinations in First-Line Non-Small Cell Lung Cancer.
Barbara Melosky, Rosalyn Juergens, +5 authors, Quincy Chu.
Oncologist, 2019 May 30; 25(1). PMID: 31138727    Free PMC article.
Therapeutic Monoclonal Antibodies Targeting Immune Checkpoints for the Treatment of Solid Tumors.
Nicholas Gravbrot, Kacy Gilbert-Gard, +4 authors, Srinath Sundararajan.
Antibodies (Basel), 2019 Oct 24; 8(4). PMID: 31640266    Free PMC article.
Review.
Immunotherapy in Ovarian Cancer.
Weimin Wang, Janice Rebecca Liu, Weiping Zou.
Surg Oncol Clin N Am, 2019 May 14; 28(3). PMID: 31079799    Free PMC article.
Review.
Endocrine toxicity in cancer patients treated with nivolumab or pembrolizumab: results of a large multicentre study.
E M Presotto, G Rastrelli, +10 authors, A Peri.
J Endocrinol Invest, 2019 Sep 23; 43(3). PMID: 31542865
Infiltration of tumor-associated macrophages is involved in tumor programmed death-ligand 1 expression in early lung adenocarcinoma.
Toshiyuki Shima, Masayuki Shimoda, +8 authors, Yae Kanai.
Cancer Sci, 2019 Dec 11; 111(2). PMID: 31821665    Free PMC article.
Acute tubulointerstitial nephritis and IgM deposits on glomerular capillary walls after immunotherapy with nivolumab for metastatic renal cell carcinoma.
Taisuke Irifuku, Ayaka Satoh, +2 authors, Takao Masaki.
CEN Case Rep, 2019 Oct 13; 9(1). PMID: 31605271    Free PMC article.
An intrinsic role of IL-33 in Treg cell-mediated tumor immunoevasion.
Aikaterini Hatzioannou, Aggelos Banos, +15 authors, Panayotis Verginis.
Nat Immunol, 2019 Dec 18; 21(1). PMID: 31844326    Free PMC article.
High RIG-I expression in ovarian cancer associates with an immune-escape signature and poor clinical outcome.
Dominik Wolf, Heidi Fiegl, +7 authors, Maximilian Boesch.
Int J Cancer, 2019 Dec 05; 146(7). PMID: 31800094    Free PMC article.
Immune Checkpoint Inhibitor Therapy in Patients With Preexisting Inflammatory Bowel Disease.
Hamzah Abu-Sbeih, David M Faleck, +26 authors, Yinghong Wang.
J Clin Oncol, 2019 Dec 05; 38(6). PMID: 31800340    Free PMC article.
Immune Checkpoint Inhibitor Myocarditis: Pathophysiological Characteristics, Diagnosis, and Treatment.
Nicolas Palaskas, Juan Lopez-Mattei, +2 authors, Anita Deswal.
J Am Heart Assoc, 2020 Jan 22; 9(2). PMID: 31960755    Free PMC article.
Review.
Smoking and Risk of Colorectal Cancer Sub-Classified by Tumor-Infiltrating T Cells.
Tsuyoshi Hamada, Jonathan A Nowak, +23 authors, Shuji Ogino.
J Natl Cancer Inst, 2018 Oct 13; 111(1). PMID: 30312431    Free PMC article.
Identification and characterization of an alternative cancer-derived PD-L1 splice variant.
Nadia B Hassounah, Venkat S Malladi, +10 authors, Esra A Akbay.
Cancer Immunol Immunother, 2018 Dec 20; 68(3). PMID: 30564890    Free PMC article.
Mismatch Repair Deficiency Drives Durable Complete Remission by Targeting Programmed Death Receptor 1 in a Metastatic Luminal Breast Cancer Patient.
Carlo Fremd, Mario Hlevnjak, +13 authors, Andreas Schneeweiss.
Breast Care (Basel), 2019 Apr 26; 14(1). PMID: 31019444    Free PMC article.
Implications of Immunotherapy in Hepatobiliary Tumors.
Aline Gottlieb, Jan Best, Ali Canbay.
Visc Med, 2019 Jul 18; 35(1). PMID: 31312646    Free PMC article.
Review.
Immune-Checkpoint Protein VISTA Regulates Antitumor Immunity by Controlling Myeloid Cell-Mediated Inflammation and Immunosuppression.
Wenwen Xu, Juan Dong, +10 authors, Li Wang.
Cancer Immunol Res, 2019 Jul 26; 7(9). PMID: 31340983    Free PMC article.
Fibronectin in Cancer: Friend or Foe.
Tsung-Cheng Lin, Cheng-Han Yang, +3 authors, Hung-Chi Cheng.
Cells, 2019 Dec 22; 9(1). PMID: 31861892    Free PMC article.
Review.
Immune recurrence score using 7 immunoregulatory protein expressions can predict recurrence in stage I-III breast cancer patients.
Dae-Won Lee, Han Suk Ryu, +14 authors, Seock-Ah Im.
Br J Cancer, 2019 Jul 12; 121(3). PMID: 31292534    Free PMC article.
Bidirectional Crosstalk Between Cancer Stem Cells and Immune Cell Subsets.
Luise Müller, Antje Tunger, +6 authors, Marc Schmitz.
Front Immunol, 2020 Mar 03; 11. PMID: 32117287    Free PMC article.
Review.
Advanced Cancer Imaging Applied in the Comparative Setting.
David M Vail, Amy K LeBlanc, Robert Jeraj.
Front Oncol, 2020 Mar 03; 10. PMID: 32117739    Free PMC article.
Therapeutic PD-L1 antibodies are more effective than PD-1 antibodies in blocking PD-1/PD-L1 signaling.
Annika De Sousa Linhares, Claire Battin, +8 authors, Peter Steinberger.
Sci Rep, 2019 Aug 09; 9(1). PMID: 31391510    Free PMC article.
Comparison of continuous measures across diagnostic PD-L1 assays in non-small cell lung cancer using automated image analysis.
Moritz Widmaier, Tobias Wiestler, +8 authors, Marlon C Rebelatto.
Mod Pathol, 2019 Sep 19; 33(3). PMID: 31527709    Free PMC article.
Novel ProCore 25-gauge needle for endobronchial ultrasound-guided transbronchial needle aspiration reduces the puncture time and frequency, with comparable diagnostic rate for mediastinal and hilar lymphadenopathy.
Li Yang, Ye Gu, +3 authors, Hao Wang.
Thorac Cancer, 2020 Jan 29; 11(3). PMID: 31989777    Free PMC article.
Extracellular vesicles: important collaborators in cancer progression.
Shinya Sato, Alissa M Weaver.
Essays Biochem, 2018 Apr 19; 62(2). PMID: 29666212    Free PMC article.
Review.
Premature Clinical Trial Discontinuation in the Era of Immune Checkpoint Inhibitors.
Monica Khunger, Sagar Rakshit, +4 authors, Petros Grivas.
Oncologist, 2018 Aug 03; 23(12). PMID: 30068783    Free PMC article.
Frontline immunotherapy treatment with nivolumab and ipilimumab in metastatic renal cell cancer: a new standard of care.
Amanda Nizam, Jeanny B Aragon-Ching.
Cancer Biol Ther, 2018 Oct 18; 20(1). PMID: 30332546    Free PMC article.
A novel humanized anti-PD-1 monoclonal antibody potentiates therapy in oral squamous cell carcinoma.
Y Cai, Fei Wang, +3 authors, Z Sun.
Invest New Drugs, 2018 Oct 29; 37(5). PMID: 30368626
An update: emerging drugs to treat squamous cell carcinomas of the head and neck.
Yoon Se Lee, Daniel E Johnson, Jennifer R Grandis.
Expert Opin Emerg Drugs, 2018 Nov 01; 23(4). PMID: 30376740    Free PMC article.
Review.
VISTA expressed in tumour cells regulates T cell function.
Kumuluzi Mulati, Junzo Hamanishi, +14 authors, Masaki Mandai.
Br J Cancer, 2018 Nov 02; 120(1). PMID: 30382166    Free PMC article.
Tumour-targeting bacteria engineered to fight cancer.
Shibin Zhou, Claudia Gravekamp, David Bermudes, Ke Liu.
Nat Rev Cancer, 2018 Nov 09; 18(12). PMID: 30405213    Free PMC article.
Highly Cited. Review.
18F-FDG PET/CT for Monitoring of Ipilimumab Therapy in Patients with Metastatic Melanoma.
Kimiteru Ito, Rebecca Teng, +7 authors, Wolfgang A Weber.
J Nucl Med, 2018 Nov 11; 60(3). PMID: 30413661    Free PMC article.
Gene landscape and correlation between B-cell infiltration and programmed death ligand 1 expression in lung adenocarcinoma patients from The Cancer Genome Atlas data set.
Kuo-Hao Ho, Chih-Ju Chang, +5 authors, Ku-Chung Chen.
PLoS One, 2018 Dec 07; 13(12). PMID: 30521597    Free PMC article.
Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation.
Irena Kaplanov, Yaron Carmi, +6 authors, Ron N Apte.
Proc Natl Acad Sci U S A, 2018 Dec 14; 116(4). PMID: 30545915    Free PMC article.
Highly Cited.
Cell death pathologies: targeting death pathways and the immune system for cancer therapy.
Francesca Pentimalli, Sandro Grelli, +2 authors, Ivano Amelio.
Genes Immun, 2018 Dec 20; 20(7). PMID: 30563970    Free PMC article.
Review.
HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers.
Xiulei Mo, Cong Tang, +3 authors, Haian Fu.
Cell Chem Biol, 2019 Jan 15; 26(3). PMID: 30639259    Free PMC article.
Efficacy and Safety of Avelumab for Patients With Recurrent or Refractory Ovarian Cancer: Phase 1b Results From the JAVELIN Solid Tumor Trial.
Mary L Disis, Matthew H Taylor, +14 authors, James L Gulley.
JAMA Oncol, 2019 Jan 25; 5(3). PMID: 30676622    Free PMC article.
Highly Cited.
APOBEC-related mutagenesis and neo-peptide hydrophobicity: implications for response to immunotherapy.
Amélie Boichard, Timothy V Pham, +6 authors, Razelle Kurzrock.
Oncoimmunology, 2019 Feb 07; 8(3). PMID: 30723579    Free PMC article.
Antitumor response to microscopic melanoma in the gastric mucosa mimicking ipilimumab-induced gastritis.
Elisa Bello, Justine V Cohen, Mari Mino-Kenudson, Michael Dougan.
J Immunother Cancer, 2019 Feb 13; 7(1). PMID: 30744698    Free PMC article.
The prognostic landscape of interactive biological processes presents treatment responses in cancer.
Bin He, Rui Gao, +13 authors, Quentin Liu.
EBioMedicine, 2019 Feb 26; 41. PMID: 30799199    Free PMC article.
The Changing Landscape of Systemic Treatment of Advanced Hepatocellular Carcinoma: New Targeted Agents and Immunotherapies.
Jens U Marquardt, Anna Saborowski, Carolin Czauderna, Arndt Vogel.
Target Oncol, 2019 Feb 26; 14(2). PMID: 30805831
Review.
Prognostic and Predictive Immunohistochemistry-Based Biomarkers in Cancer and Immunotherapy.
Emanuelle M Rizk, Robyn D Gartrell, +4 authors, Yvonne M Saenger.
Hematol Oncol Clin North Am, 2019 Mar 06; 33(2). PMID: 30833001    Free PMC article.
Review.
Mechanisms involved in IL-15 superagonist enhancement of anti-PD-L1 therapy.
Karin M Knudson, Kristin C Hicks, +2 authors, Sofia R Gameiro.
J Immunother Cancer, 2019 Mar 23; 7(1). PMID: 30898149    Free PMC article.
Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors.
Xiaopin Duan, Christina Chan, +3 authors, Wenbin Lin.
Nat Commun, 2019 Apr 25; 10(1). PMID: 31015397    Free PMC article.
Emerging therapies for non-small cell lung cancer.
Chao Zhang, Natasha B Leighl, Yi-Long Wu, Wen-Zhao Zhong.
J Hematol Oncol, 2019 Apr 27; 12(1). PMID: 31023335    Free PMC article.
Highly Cited. Review.
Systematic review and case series: flexible sigmoidoscopy identifies most cases of checkpoint inhibitor-induced colitis.
Andrew P Wright, Marc S Piper, Shrinivas Bishu, Ryan W Stidham.
Aliment Pharmacol Ther, 2019 Apr 30; 49(12). PMID: 31035308    Free PMC article.
Systematic Review.
PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy.
Xinyi Tu, Bo Qin, +16 authors, Zhenkun Lou.
Mol Cell, 2019 May 06; 74(6). PMID: 31053471    Free PMC article.
Determining cell type abundance and expression from bulk tissues with digital cytometry.
Aaron M Newman, Chloé B Steen, +9 authors, Ash A Alizadeh.
Nat Biotechnol, 2019 May 08; 37(7). PMID: 31061481    Free PMC article.
Highly Cited.
Interaction of CD99 and its ligand upregulates IL-6 and TNF-α upon T cell activation.
Nuchjira Takheaw, Papawadee Earwong, +2 authors, Watchara Kasinrerk.
PLoS One, 2019 May 24; 14(5). PMID: 31120992    Free PMC article.
Intradermal DNA vaccination combined with dual CTLA-4 and PD-1 blockade provides robust tumor immunity in murine melanoma.
Spela Kos, Alessandra Lopes, +6 authors, Gaelle Vandermeulen.
PLoS One, 2019 Jun 01; 14(5). PMID: 31150505    Free PMC article.
Understanding heterogeneous tumor microenvironment in metastatic melanoma.
Yiyi Yan, Alexey A Leontovich, +11 authors, Svetomir N Markovic.
PLoS One, 2019 Jun 06; 14(6). PMID: 31166985    Free PMC article.
m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.
Seungwon Yang, Jiangbo Wei, +8 authors, Yu-Ying He.
Nat Commun, 2019 Jun 27; 10(1). PMID: 31239444    Free PMC article.
Highly Cited.
The Prognostic Landscape of Tumor-Infiltrating Immune Cells and Immune Checkpoints in Glioblastoma.
Shiman Wu, Wenli Yang, +4 authors, Zhenwei Yao.
Technol Cancer Res Treat, 2019 Aug 28; 18. PMID: 31451090    Free PMC article.
[Influence of immunomodulators on urological imaging].
F Peisen, W Thaiss, +6 authors, S Kaufmann.
Urologe A, 2019 Nov 11; 58(12). PMID: 31705144
Review.
Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance.
Dhanya K Nambiar, Todd Aguilera, +16 authors, Quynh Thu Le.
J Clin Invest, 2019 Nov 12; 129(12). PMID: 31710313    Free PMC article.
Immune Checkpoint Inhibitors in Acute Myeloid Leukemia: Novel Combinations and Therapeutic Targets.
Maximilian Stahl, Aaron D Goldberg.
Curr Oncol Rep, 2019 Mar 25; 21(4). PMID: 30904967
Review.
Platinum Derivatives Effects on Anticancer Immune Response.
Cédric Rébé, Lucie Demontoux, Thomas Pilot, François Ghiringhelli.
Biomolecules, 2019 Dec 22; 10(1). PMID: 31861811    Free PMC article.
Review.
A TP53-associated gene signature for prediction of prognosis and therapeutic responses in lung squamous cell carcinoma.
Feng Xu, Haoyu Lin, +4 authors, Yongsong Chen.
Oncoimmunology, 2020 Mar 12; 9(1). PMID: 32158625    Free PMC article.
[Chinese Experts Consensus on Immune Checkpoint Inhibitors for Non-small Cell Lung Cancer (2019 version)].
Caicun Zhou, Jie Wang, +13 authors, Shukui Qin.
Zhongguo Fei Ai Za Zhi, 2020 Feb 26; 23(2). PMID: 32093450    Free PMC article.
A phase II open label, randomised study of ipilimumab with temozolomide versus temozolomide alone after surgery and chemoradiotherapy in patients with recently diagnosed glioblastoma: the Ipi-Glio trial protocol.
Nicholas F Brown, Stasya M Ng, +8 authors, Paul Mulholland.
BMC Cancer, 2020 Mar 14; 20(1). PMID: 32164579    Free PMC article.
Gastrointestinal and Hepatic Complications of Immunotherapy: Current Management and Future Perspectives.
Michael Dougan.
Curr Gastroenterol Rep, 2020 Mar 19; 22(4). PMID: 32185493
Review.
Cutaneous Adverse Events of Anti-PD-1 Therapy and BRAF Inhibitors.
Subashini Sharon Gnanendran, Lauren Maree Turner, +2 authors, Andrew Charles Miller.
Curr Treat Options Oncol, 2020 Mar 21; 21(4). PMID: 32193712
Review.
GD2 chimeric antigen receptor modified T cells in synergy with sub-toxic level of doxorubicin targeting osteosarcomas.
Monrat Chulanetra, Atthapan Morchang, +9 authors, Lung-Ji Chang.
Am J Cancer Res, 2020 Mar 21; 10(2). PMID: 32195035    Free PMC article.
Combination of mAb-AR20.5, anti-PD-L1 and PolyICLC inhibits tumor progression and prolongs survival of MUC1.Tg mice challenged with pancreatic tumors.
Kamiya Mehla, Jarrod Tremayne, +10 authors, Michael A Hollingsworth.
Cancer Immunol Immunother, 2017 Dec 06; 67(3). PMID: 29204701    Free PMC article.
Armed oncolytic viruses: A kick-start for anti-tumor immunity.
J F de Graaf, L de Vor, R A M Fouchier, B G van den Hoogen.
Cytokine Growth Factor Rev, 2018 Mar 27; 41. PMID: 29576283    Free PMC article.
Highly Cited. Review.
Building Potent Chimeric Antigen Receptor T Cells With CRISPR Genome Editing.
Jie Liu, Guangyu Zhou, Li Zhang, Qi Zhao.
Front Immunol, 2019 Apr 04; 10. PMID: 30941126    Free PMC article.
Review.
Combining Immune Checkpoint Inhibitors with Anti-Angiogenic Agents.
Paola Ciciola, Priscilla Cascetta, +2 authors, Roberto Bianco.
J Clin Med, 2020 Mar 07; 9(3). PMID: 32138216    Free PMC article.
Review.
Targeting the Complement Pathway as a Therapeutic Strategy in Lung Cancer.
Emily K Kleczko, Jeff W Kwak, Erin L Schenk, Raphael A Nemenoff.
Front Immunol, 2019 May 28; 10. PMID: 31134065    Free PMC article.
Review.
Biology and Therapeutic Targets of Colorectal Serrated Adenocarcinoma; Clues for a Histologically Based Treatment against an Aggressive Tumor.
Begoña Alburquerque-González, Fernando F López-Calderón, +3 authors, Pablo Conesa-Zamora.
Int J Mol Sci, 2020 Mar 19; 21(6). PMID: 32183342    Free PMC article.
Review.
Different sensitivities of senescent breast cancer cells to immune cell-mediated cytotoxicity.
Touko Inao, Hitoshi Kotani, +5 authors, Mamoru Harada.
Cancer Sci, 2019 Jun 30; 110(9). PMID: 31250942    Free PMC article.
The Emerging Jamboree of Transformative Therapies for Autoimmune Diseases.
José M Carballido, Camille Regairaz, +3 authors, Michael Kammüller.
Front Immunol, 2020 Apr 17; 11. PMID: 32296421    Free PMC article.
Review.
Tolerability and efficacy of durvalumab in Japanese patients with advanced solid tumors.
Yutaka Fujiwara, Haruo Iguchi, +7 authors, Toshiyuki Kozuki.
Cancer Sci, 2019 Mar 21; 110(5). PMID: 30891877    Free PMC article.
Examining Peripheral and Tumor Cellular Immunome in Patients With Cancer.
Eda K Holl, Victoria N Frazier, +3 authors, Smita K Nair.
Front Immunol, 2019 Aug 17; 10. PMID: 31417550    Free PMC article.
Up-regulation of indoleamine 2,3-dioxygenase 1 (IDO1) expression and catalytic activity is associated with immunosuppression and poor prognosis in penile squamous cell carcinoma patients.
Qiang-Hua Zhou, Hui Han, +13 authors, Ran-Yi Liu.
Cancer Commun (Lond), 2020 Mar 04; 40(1). PMID: 32125093    Free PMC article.
Tertiary Lymphoid Organs in Cancer Immunology: Mechanisms and the New Strategy for Immunotherapy.
Liangbin Lin, Xiang Hu, Huiyuan Zhang, Hongbo Hu.
Front Immunol, 2019 Jul 10; 10. PMID: 31281318    Free PMC article.
Review.
Immune Checkpoint Inhibitor Rechallenge After Immune-Related Adverse Events in Patients With Cancer.
Charles Dolladille, Stéphane Ederhy, +11 authors, Joachim Alexandre.
JAMA Oncol, 2020 Apr 17; 6(6). PMID: 32297899    Free PMC article.
Advanced stage at diagnosis and elevated mortality among US patients with cancer infected with HIV in the National Cancer Data Base.
Anna E Coghill, Xuesong Han, +3 authors, Meredith S Shiels.
Cancer, 2019 May 03; 125(16). PMID: 31050361    Free PMC article.
Prognostic value of programmed cell death ligand 1 (PD-L1) for hepatocellular carcinoma: a meta-analysis.
Xiao-Song Li, Jun-Wei Li, Hui Li, Tao Jiang.
Biosci Rep, 2020 Apr 08; 40(4). PMID: 32255189    Free PMC article.
A Case of Isolated Adrenocorticotropic Hormone Deficiency Caused by Pembrolizumab.
Tomoaki Bekki, Yuji Takakura, +5 authors, Hideki Ohdan.
Case Rep Oncol, 2020 Apr 21; 13(1). PMID: 32308578    Free PMC article.
Current Approaches for Personalized Therapy of Soft Tissue Sarcomas.
Kirill I Kirsanov, Ekaterina A Lesovaya, +3 authors, Marianna G Yakubovskaya.
Sarcoma, 2020 Apr 23; 2020. PMID: 32317857    Free PMC article.
Review.
Durvalumab in frail and elderly patients with stage four non-small cell lung cancer: Study protocol of the randomized phase II DURATION trial.
Jonas Kuon, Adriane Hommertgen, +8 authors, Michael Thomas.
Trials, 2020 Apr 24; 21(1). PMID: 32321565    Free PMC article.
Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 2: Approaches to Predict and Identify Late Recurrence, Research Directions.
Ryan J O Dowling, Joseph A Sparano, +29 authors, Daniel F Hayes.
JNCI Cancer Spectr, 2020 Apr 28; 3(4). PMID: 32337478    Free PMC article.
Effects of anti-PD-1 immunotherapy on tumor regression: insights from a patient-derived xenograft model.
Asunción Martín-Ruiz, Carmen Fiuza-Luces, +7 authors, Mariano Provencio.
Sci Rep, 2020 Apr 29; 10(1). PMID: 32341383    Free PMC article.
Analysis of Lung Adenocarcinoma Subtypes Based on Immune Signatures Identifies Clinical Implications for Cancer Therapy.
Feng Xu, Jie-Xin Chen, +4 authors, Yong-Song Chen.
Mol Ther Oncolytics, 2020 Apr 30; 17. PMID: 32346613    Free PMC article.
Solid Tumors Challenges and New Insights of CAR T Cell Engineering.
Safa Tahmasebi, Reza Elahi, Abdolreza Esmaeilzadeh.
Stem Cell Rev Rep, 2019 Jun 05; 15(5). PMID: 31161552
Review.
Precise cell behaviors manipulation through light-responsive nano-regulators: recent advance and perspective.
Do Cong Thang, Zhimin Wang, Xiaoling Lu, Bengang Xing.
Theranostics, 2019 Jun 28; 9(11). PMID: 31244956    Free PMC article.
Review.
Optimal PD-L1-high cutoff for association with overall survival in patients with urothelial cancer treated with durvalumab monotherapy.
Magdalena Zajac, Jiabu Ye, +7 authors, Jill Walker.
PLoS One, 2020 Apr 28; 15(4). PMID: 32339189    Free PMC article.
Heterogeneous responses in hepatocellular carcinoma: the achilles heel of immune checkpoint inhibitors.
Zuyuan Lin, Di Lu, +2 authors, Xiao Xu.
Am J Cancer Res, 2020 May 06; 10(4). PMID: 32368387    Free PMC article.
Review.
Tumor Hypoxia: Impact on Radiation Therapy and Molecular Pathways.
Brita Singers Sørensen, Michael R Horsman.
Front Oncol, 2020 May 07; 10. PMID: 32373534    Free PMC article.
Review.
An Improved Patient-Derived Xenograft Humanized Mouse Model for Evaluation of Lung Cancer Immune Responses.
Ismail M Meraz, Mourad Majidi, +9 authors, Jack A Roth.
Cancer Immunol Res, 2019 Jun 13; 7(8). PMID: 31186248    Free PMC article.
Engineering strategies to overcome the current roadblocks in CAR T cell therapy.
Sarwish Rafiq, Christopher S Hackett, Renier J Brentjens.
Nat Rev Clin Oncol, 2019 Dec 19; 17(3). PMID: 31848460    Free PMC article.
Highly Cited. Review.
The prevalence and prognostic and clinicopathological value of PD-L1 and PD-L2 in renal cell carcinoma patients: a systematic review and meta-analysis involving 3,389 patients.
Yi Lu, Yuxuan Song, +9 authors, Xiaoqiang Liu.
Transl Androl Urol, 2020 May 19; 9(2). PMID: 32420142    Free PMC article.
Oncologic Emergencies: Immune-Based Cancer Therapies and Complications.
Brit Long, Elizabeth Brém, Alex Koyfman.
West J Emerg Med, 2020 May 19; 21(3). PMID: 32421502    Free PMC article.
Review.
Immune Checkpoint Inhibitor-Related Cytokine Release Syndrome: Analysis of WHO Global Pharmacovigilance Database.
Alessandro Ceschi, Roberta Noseda, Karine Palin, Katia Verhamme.
Front Pharmacol, 2020 May 20; 11. PMID: 32425791    Free PMC article.
Histologic patterns of liver injury induced by anti-PD-1 therapy.
Dongwei Zhang, John Hart, +8 authors, Jinping Lai.
Gastroenterol Rep (Oxf), 2020 May 30; 8(1). PMID: 32467761    Free PMC article.
Cancer therapy-induced cardiomyopathy: can human induced pluripotent stem cell modelling help prevent it?
Jonathan P Stack, Javid Moslehi, Nazish Sayed, Joseph C Wu.
Eur Heart J, 2018 Jan 30; 40(22). PMID: 29377985    Free PMC article.
Review.
Association of Germline Variants in Natural Killer Cells With Tumor Immune Microenvironment Subtypes, Tumor-Infiltrating Lymphocytes, Immunotherapy Response, Clinical Outcomes, and Cancer Risk.
Xue Xu, Jianqiang Li, +7 authors, Edwin Wang.
JAMA Netw Open, 2019 Sep 05; 2(9). PMID: 31483464    Free PMC article.
Current Clinical Progress of PD-1/PD-L1 Immunotherapy and Potential Combination Treatment in Non-Small Cell Lung Cancer.
Jia-Xin Li, Ju-Min Huang, +4 authors, Pei-Yu Yan.
Integr Cancer Ther, 2019 Dec 17; 18. PMID: 31838881    Free PMC article.
Review.
Adipocytes promote tumor progression and induce PD-L1 expression via TNF-α/IL-6 signaling.
Zhi Li, Cai Zhang, +4 authors, Hui Liu.
Cancer Cell Int, 2020 Jun 02; 20. PMID: 32477009    Free PMC article.
Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours.
David S Hong, Yoon-Koo Kang, +20 authors, Muhammad S Beg.
Br J Cancer, 2020 Apr 03; 122(11). PMID: 32238921    Free PMC article.
The efficacy and safety of immune checkpoint inhibitors in non-small cell lung cancer patients of different age groups: a meta-analysis.
S-Y Zheng, H-J Cui, +8 authors, X Jiang.
Clin Transl Oncol, 2019 Nov 22; 22(7). PMID: 31748961    Free PMC article.
Inhibition of Programmed Death Receptor-1/Programmed Death Ligand-1 Interactions by Ginsenoside Metabolites.
Nam-Hui Yim, Young Soo Kim, Hwan-Suck Chung.
Molecules, 2020 May 06; 25(9). PMID: 32365500    Free PMC article.
Regression of Papillary Thyroid Cancer during Nivolumab for Renal Cell Cancer.
Andrea Palermo, Andrea Napolitano, +9 authors, Daniele Santini.
Eur Thyroid J, 2020 Jun 12; 9(3). PMID: 32523892    Free PMC article.
Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex.
Sarah C Garrett-Thomson, Aldo Massimi, +8 authors, Steven C Almo.
PLoS One, 2020 Jun 05; 15(6). PMID: 32497097    Free PMC article.
Near Infrared Light Triggered Photo/Immuno-Therapy Toward Cancers.
Xiaoxue Xu, Hongxu Lu, Ruda Lee.
Front Bioeng Biotechnol, 2020 Jun 13; 8. PMID: 32528941    Free PMC article.
Review.
Incidence and dose-volume relationship of radiation pneumonitis after concurrent chemoradiotherapy followed by durvalumab for locally advanced non-small cell lung cancer.
Satoshi Saito, Takanori Abe, +10 authors, Shingo Kato.
Clin Transl Radiat Oncol, 2020 Jun 13; 23. PMID: 32529055    Free PMC article.
The different benefits and side effects of nivolumab combined with ipilimumab in diverse cancer: A Protocol for Systematic Review.
Hongxuan Tong, Yu Hao, +2 authors, Tao Lu.
Medicine (Baltimore), 2020 Mar 17; 99(11). PMID: 32176058    Free PMC article.
Systematic Review.
Current Molecular Markers of Melanoma and Treatment Targets.
Kevin Yang, Allen S W Oak, +2 authors, Andrzej T Slominski.
Int J Mol Sci, 2020 May 21; 21(10). PMID: 32429485    Free PMC article.
Review.
Preparation of Biphenyl-Conjugated Bromotyrosine for Inhibition of PD-1/PD-L1 Immune Checkpoint Interactions.
Eun-Hye Kim, Masuki Kawamoto, +3 authors, Hideyuki Miyatake.
Int J Mol Sci, 2020 May 28; 21(10). PMID: 32455628    Free PMC article.
Efficacy of Nivolumab for Head and Neck Cancer Patients with Primary Sites and Histological Subtypes Excluded from the CheckMate-141 Trial.
Yasuyoshi Sato, Naoki Fukuda, +9 authors, Shunji Takahashi.
Cancer Manag Res, 2020 Jun 26; 12. PMID: 32581587    Free PMC article.
Immune Checkpoints Contribute Corneal Immune Privilege: Implications for Dry Eye Associated with Checkpoint Inhibitors.
Junko Hori, Tomoyuki Kunishige, Yuji Nakano.
Int J Mol Sci, 2020 Jun 04; 21(11). PMID: 32486493    Free PMC article.
Review.
Pembrolizumab-associated nephrotic syndrome recovered from transient hemodialysis in a patient with lung cancer.
Kento Ishibuchi, Takamasa Iwakura, +2 authors, Ryuichi Furuya.
CEN Case Rep, 2020 Mar 15; 9(3). PMID: 32170578    Free PMC article.
Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia.
Adam J Lamble, Yoko Kosaka, +19 authors, Evan F Lind.
Proc Natl Acad Sci U S A, 2020 Jun 10; 117(25). PMID: 32513686    Free PMC article.
Detecting and Filtering Immune-Related Adverse Events Signal Based on Text Mining and Observational Health Data Sciences and Informatics Common Data Model: Framework Development Study.
Yue Yu, Kathryn Ruddy, +7 authors, Guoqian Jiang.
JMIR Med Inform, 2020 Jun 13; 8(6). PMID: 32530430    Free PMC article.
Pituitary dysfunction induced by immune checkpoint inhibitors is associated with better overall survival in both malignant melanoma and non-small cell lung carcinoma: a prospective study.
Tomoko Kobayashi, Shintaro Iwama, +24 authors, Hiroshi Arima.
J Immunother Cancer, 2020 Jul 02; 8(2). PMID: 32606047    Free PMC article.
Systemic treatment of hepatocellular carcinoma: from sorafenib to combination therapies.
Christoph Roderburg, Burcin Özdirik, +2 authors, Frank Tacke.
Hepat Oncol, 2020 Jul 11; 7(2). PMID: 32647565    Free PMC article.
Review.
T-cells expressing a chimeric-PD1-Dap10-CD3zeta receptor reduce tumour burden in multiple murine syngeneic models of solid cancer.
Geoffrey Parriott, Kelsey Deal, +3 authors, Amorette Barber.
Immunology, 2020 Mar 08; 160(3). PMID: 32144940    Free PMC article.
[Research progress on PD-1 inhibitors in lymphoma therapy].
Y L Liu, Y Q Song, J Zhu.
Zhonghua Xue Ye Xue Za Zhi, 2016 Oct 11; 37(9). PMID: 27719732    Free PMC article.
Fluoropyrimidine Modulation of the Anti-Tumor Immune Response-Prospects for Improved Colorectal Cancer Treatment.
William H Gmeiner.
Cancers (Basel), 2020 Jun 25; 12(6). PMID: 32575843    Free PMC article.
Review.
Immunotherapy in the Treatment of Metastatic Melanoma: Current Knowledge and Future Directions.
Massimo Ralli, Andrea Botticelli, +6 authors, Antonio Greco.
J Immunol Res, 2020 Jul 17; 2020. PMID: 32671117    Free PMC article.
Review.
Pembrolizumab-Induced Myasthenic Crisis with HyperCKemia in a Patient with Thymoma.
Ji Hye Shin, Yoon Ji Choi, Jungyeun Lee, Seol Hee Baek.
J Clin Neurol, 2020 Jul 14; 16(3). PMID: 32657073    Free PMC article.
Peripheral Blood Biomarkers Associated With Outcome in Non-small Cell Lung Cancer Patients Treated With Nivolumab and Durvalumab Monotherapy.
Meilin Jiang, Wenying Peng, +11 authors, Lin Wu.
Front Oncol, 2020 Jul 23; 10. PMID: 32695663    Free PMC article.
Cancer immunotherapy using checkpoint blockade.
Antoni Ribas, Jedd D Wolchok.
Science, 2018 Mar 24; 359(6382). PMID: 29567705    Free PMC article.
Highly Cited. Review.
Tryptophan Catabolism as Immune Mechanism of Primary Resistance to Anti-PD-1.
Andrea Botticelli, Silvia Mezi, +11 authors, Paolo Marchetti.
Front Immunol, 2020 Aug 01; 11. PMID: 32733441    Free PMC article.
Clinical and Recent Patents Applications of PD-1/PD-L1 Targeting Immunotherapy in Cancer Treatment-Current Progress, Strategy, and Future Perspective.
Libin Guo, Ran Wei, Yao Lin, Hang Fai Kwok.
Front Immunol, 2020 Aug 01; 11. PMID: 32733486    Free PMC article.
Review.
An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis.
Xiaoqiang Qi, Emily Schepers, +4 authors, Guangfu Li.
J Vis Exp, 2019 Oct 01; (151). PMID: 31566616    Free PMC article.
Tumors Resistant to Checkpoint Inhibitors Can Become Sensitive after Treatment with Vascular Disrupting Agents.
Michael R Horsman, Thomas R Wittenborn, Patricia S Nielsen, Pernille B Elming.
Int J Mol Sci, 2020 Jul 10; 21(13). PMID: 32640548    Free PMC article.
Obesity and CD8 T cell metabolism: Implications for anti-tumor immunity and cancer immunotherapy outcomes.
William J Turbitt, Claire Buchta Rosean, K Scott Weber, Lyse A Norian.
Immunol Rev, 2020 Mar 12; 295(1). PMID: 32157710    Free PMC article.
Review.
mRNA Display Discovery of a Novel Programmed Death Ligand 1 (PD-L1) Binding Peptide (a Peptide Ligand for PD-L1).
Golnaz Kamalinia, Brian J Engel, +6 authors, Richard W Roberts.
ACS Chem Biol, 2020 May 01; 15(6). PMID: 32352272    Free PMC article.
Immune Checkpoint Inhibitor-Associated Primary Adrenal Insufficiency: WHO VigiBase Report Analysis.
Virginie Grouthier, Bénédicte Lebrun-Vignes, +4 authors, Anne Bachelot.
Oncologist, 2020 May 12; 25(8). PMID: 32390168    Free PMC article.
Targeted therapies in gynecological cancers: a comprehensive review of clinical evidence.
Qiao Wang, Hongling Peng, +2 authors, Xia Zhao.
Signal Transduct Target Ther, 2020 Jul 31; 5(1). PMID: 32728057    Free PMC article.
Review.
Interferon-γ induced PD-L1 expression and soluble PD-L1 production in gastric cancer.
Yushi Imai, Tetsuhiro Chiba, +18 authors, Naoya Kato.
Oncol Lett, 2020 Aug 13; 20(3). PMID: 32782533    Free PMC article.
Early response of bone metastases can predict tumor response in patients with non-small-cell lung cancer with bone metastases in the treatment with nivolumab.
Eiji Nakata, Shinsuke Sugihara, +8 authors, Toshifumi Ozaki.
Oncol Lett, 2020 Aug 13; 20(3). PMID: 32782615    Free PMC article.
Chimeric Antigen Receptor Therapy.
Carl H June, Michel Sadelain.
N Engl J Med, 2018 Jul 05; 379(1). PMID: 29972754    Free PMC article.
Highly Cited. Review.
Risk factors of immune checkpoint inhibitor-related interstitial lung disease in patients with lung cancer: a single-institution retrospective study.
Naoto Okada, Rie Matsuoka, +6 authors, Keisuke Ishizawa.
Sci Rep, 2020 Aug 15; 10(1). PMID: 32792640    Free PMC article.
Past, Present, and Future of Anticancer Nanomedicine.
Kyungeun Kim, Dongwoo Khang.
Int J Nanomedicine, 2020 Aug 22; 15. PMID: 32821098    Free PMC article.
Review.
Novel platform leveraging electronic medical record (EMR) to triage patients admitted with high-grade immune-related adverse events (irAEs) to the immune-toxicity (ITOX) service.
Osama Abu-Shawer, Prabhsimranjot Singh, +11 authors, Osama Rahma.
J Immunother Cancer, 2020 Aug 21; 8(2). PMID: 32817360    Free PMC article.
Diagnosis and Treatment of Rheumatic Adverse Events Related to Immune Checkpoint Inhibitors.
Yan Xiao, Lin Zeng, +6 authors, Weirong Yao.
J Immunol Res, 2020 Aug 25; 2020. PMID: 32832568    Free PMC article.
Review.
Administration of low-dose combination anti-CTLA4, anti-CD137, and anti-OX40 into murine tumor or proximal to the tumor draining lymph node induces systemic tumor regression.
Jonathan P O Hebb, Adriane R Mosley, +4 authors, Dean W Felsher.
Cancer Immunol Immunother, 2017 Sep 15; 67(1). PMID: 28905118    Free PMC article.
Plasma Level of Circular RNA hsa_circ_0000190 Correlates with Tumor Progression and Poor Treatment Response in Advanced Lung Cancers.
Yung-Hung Luo, Yi-Ping Yang, +14 authors, Mong-Lien Wang.
Cancers (Basel), 2020 Jul 08; 12(7). PMID: 32629833    Free PMC article.
IL-31 induces antitumor immunity in breast carcinoma.
Tal Kan, Erik Feldman, +4 authors, Yuval Shaked.
J Immunother Cancer, 2020 Aug 28; 8(2). PMID: 32843492    Free PMC article.
Distinct tumor immune microenvironments in primary and metastatic lesions in gastric cancer patients.
Seung-Myoung Son, Chang Gok Woo, +12 authors, Hye Sook Han.
Sci Rep, 2020 Sep 02; 10(1). PMID: 32868848    Free PMC article.
Advanced biomaterials for cancer immunotherapy.
Fan Yang, Kun Shi, +3 authors, Zhi-Yong Qian.
Acta Pharmacol Sin, 2020 Mar 04; 41(7). PMID: 32123302    Free PMC article.
Review.
The Great War of Today: Modifications of CAR-T Cells to Effectively Combat Malignancies.
Andriy Zhylko, Magdalena Winiarska, Agnieszka Graczyk-Jarzynka.
Cancers (Basel), 2020 Jul 30; 12(8). PMID: 32722109    Free PMC article.
Review.
Pathomechanisms and Clinical Implications of Myasthenic Syndromes Exacerbated and Induced by Medical Treatments.
Martin Krenn, Anna Grisold, +4 authors, Fritz Zimprich.
Front Mol Neurosci, 2020 Sep 15; 13. PMID: 32922263    Free PMC article.
Review.
IFNγ and TNFα synergistically promote galectin 9 secretion by human osteosarcoma cells MG-63 to prevent T cell killing.
Yuchang Liu, Junzhong Luo, +2 authors, Xuan Wang.
Int J Clin Exp Pathol, 2020 Sep 15; 13(8). PMID: 32922595    Free PMC article.
Cancer immunotherapy using a polysaccharide from Codium fragile in a murine model.
Hae-Bin Park, Seong-Min Lim, +3 authors, Jun-O Jin.
Oncoimmunology, 2020 Sep 15; 9(1). PMID: 32923129    Free PMC article.
Delivery of Personalized Care for Locally Advanced Rectal Cancer: Incorporating Pathological, Molecular Genetic, and Immunological Biomarkers Into the Multimodal Paradigm.
Éanna J Ryan, Ben Creavin, Kieran Sheahan.
Front Oncol, 2020 Sep 15; 10. PMID: 32923389    Free PMC article.
Review.
Dermatologic toxicities to immune checkpoint inhibitor therapy: A review of histopathologic features.
Samantha R Ellis, Aren T Vierra, +2 authors, Maija Kiuru.
J Am Acad Dermatol, 2020 May 04; 83(4). PMID: 32360716    Free PMC article.
Review.
Progress of immune checkpoint LAG-3 in immunotherapy.
Chanchan Shan, Xing Li, Jian Zhang.
Oncol Lett, 2020 Sep 24; 20(5). PMID: 32963613    Free PMC article.
Review.
Immunotherapy in urothelial cancer, part 1: T-cell checkpoint inhibition in advanced or metastatic disease.
Steven S Yu, Tanya B Dorff, +3 authors, David I Quinn.
Clin Adv Hematol Oncol, 2017 Jul 28; 15(6). PMID: 28749907    Free PMC article.
Review.
The Prevalence and Prognostic Role of PD-L1 in Upper Tract Urothelial Carcinoma Patients Underwent Radical Nephroureterectomy: A Systematic Review and Meta-Analysis.
Yi Lu, Jiaqi Kang, +7 authors, Xiaoqiang Liu.
Front Oncol, 2020 Sep 26; 10. PMID: 32974145    Free PMC article.
Systematic Review.
Theranostics Applications of Nanoparticles in Cancer Immunotherapy.
Yihai Liu, Xixi Wang, +5 authors, Bin Liu.
Med Sci (Basel), 2018 Nov 15; 6(4). PMID: 30424010    Free PMC article.
Review.
The Role of Yes-Associated Protein (YAP) in Regulating Programmed Death-Ligand 1 (PD-L1) in Thoracic Cancer.
Ping-Chih Hsu, Cheng-Ta Yang, David M Jablons, Liang You.
Biomedicines, 2018 Dec 14; 6(4). PMID: 30544524    Free PMC article.
Review.
Treatment of advanced hepatocellular carcinoma: immunotherapy from checkpoint blockade to potential of cellular treatment.
Elaine Hon-Lam Siu, Anthony Wing-Hung Chan, +3 authors, Siu Tim Cheung.
Transl Gastroenterol Hepatol, 2019 Jan 04; 3. PMID: 30603725    Free PMC article.
Review.
Chimeric Antigen Receptor T-Cell Therapy: A Beacon of Hope in the Fight Against Cancer.
Syed Maaz Tariq, Syed Ali Haider, +4 authors, Anum Kamal.
Cureus, 2019 Jan 08; 10(10). PMID: 30613448    Free PMC article.
Review.
The Relative Risk and Incidence of Immune Checkpoint Inhibitors Related Pneumonitis in Patients With Advanced Cancer: A Meta-Analysis.
Ke Ma, Yali Lu, +3 authors, Yuyang Zhang.
Front Pharmacol, 2019 Jan 09; 9. PMID: 30618738    Free PMC article.
Review.
Principles of Immunotherapy: Implications for Treatment Strategies in Cancer and Infectious Diseases.
Krupa Naran, Trishana Nundalall, Shivan Chetty, Stefan Barth.
Front Microbiol, 2019 Jan 10; 9. PMID: 30622524    Free PMC article.
Review.
Cytokines, Chemokines, and Other Biomarkers of Response for Checkpoint Inhibitor Therapy in Skin Cancer.
Jennifer A Bridge, James C Lee, +2 authors, Jeffrey A Bluestone.
Front Med (Lausanne), 2019 Jan 12; 5. PMID: 30631766    Free PMC article.
Review.
Pembrolizumab-related renal toxicities: diagnosis first, treatment later.
Ben Sprangers.
Clin Kidney J, 2019 Feb 13; 12(1). PMID: 30746131    Free PMC article.
Activation of CD8⁺ T Cell Responses after Melanoma Antigen Targeting to CD169⁺ Antigen Presenting Cells in Mice and Humans.
Dieke van Dinther, Miguel Lopez Venegas, +8 authors, Joke M M den Haan.
Cancers (Basel), 2019 Feb 16; 11(2). PMID: 30764534    Free PMC article.
Immune checkpoint inhibitors: Real-world experience from India in advanced solid cancers that have progressed on chemotherapy.
Vineet Govinda Gupta, Ranga Rao Rangaraju, +2 authors, Ruchika Khetrapal.
South Asian J Cancer, 2019 Feb 16; 8(1). PMID: 30766859    Free PMC article.
Acute Interstitial Nephritis in a Patient with Non-Small Cell Lung Cancer under Immunotherapy with Nivolumab.
Panagiotis I Georgianos, Vasilios Vaios, +5 authors, Pantelis E Zebekakis.
Case Rep Nephrol, 2019 Feb 19; 2019. PMID: 30775040    Free PMC article.
Immune Check Point Inhibitor-Associated Glomerulonephritis.
Tarek Ashour, Georges Nakhoul, +2 authors, Leal Herlitz.
Kidney Int Rep, 2019 Feb 19; 4(2). PMID: 30775635    Free PMC article.
HCC Immune Surveillance and Antiviral Therapy of Hepatitis C Virus Infection.
Solomon Owusu Sekyere, Bernhard Schlevogt, +8 authors, Heiner Wedemeyer.
Liver Cancer, 2019 Mar 01; 8(1). PMID: 30815394    Free PMC article.
Merkel Cell Carcinoma: Therapeutic Update and Emerging Therapies.
Alessia Villani, Gabriella Fabbrocini, +2 authors, Massimiliano Scalvenzi.
Dermatol Ther (Heidelb), 2019 Mar 02; 9(2). PMID: 30820877    Free PMC article.
Review.
Combinatorial therapy of immune checkpoint and cancer pathways provides a novel perspective on ovarian cancer treatment.
Guyu Zhang, Chongdong Liu, +3 authors, Zhengyu Zhang.
Oncol Lett, 2019 Mar 12; 17(3). PMID: 30854033    Free PMC article.
Review.
Correlation Between PD-L2 Expression and Clinical Outcome in Solid Cancer Patients: A Meta-Analysis.
Huayu Yang, Xiaoxiang Zhou, Lejia Sun, Yilei Mao.
Front Oncol, 2019 Mar 21; 9. PMID: 30891423    Free PMC article.
Selection of patient reported outcomes questions reflecting symptoms for patients with metastatic melanoma receiving immunotherapy.
Lærke K Tolstrup, Lars Bastholt, +2 authors, Helle Pappot.
J Patient Rep Outcomes, 2019 Mar 23; 3(1). PMID: 30900035    Free PMC article.
Correlation between patients' age and cancer immunotherapy efficacy.
Qiong Wu, Qiuhong Wang, +10 authors, You Lang Zhou.
Oncoimmunology, 2019 Mar 25; 8(4). PMID: 30906662    Free PMC article.
Efficacy and safety of programmed cell death-1/programmed cell death ligand-1 inhibitors in advanced urothelial malignancy: A systematic review and meta-analysis.
Smita Pattanaik, Sumit Dey, +4 authors, Ravimohan Suryanarayan Mavuduru.
Indian J Urol, 2019 Apr 20; 35(2). PMID: 31000914    Free PMC article.
Reactive capillary hemangiomas: a novel dermatologic toxicity following anti-PD-1 treatment with SHR-1210.
Xuelian Chen, Lanying Ma, +7 authors, Binghe Xu.
Cancer Biol Med, 2019 May 24; 16(1). PMID: 31119058    Free PMC article.
Clinical utility of pembrolizumab in the management of advanced solid tumors: an evidence-based review on the emerging new data.
Pauline du Rusquec, Ombline de Calbiac, +2 authors, Jean Sebastien Frenel.
Cancer Manag Res, 2019 Jun 14; 11. PMID: 31190995    Free PMC article.
Review.
TLR4 expression correlated with PD-L1 expression indicates a poor prognosis in patients with peripheral T-cell lymphomas.
Shu Zhao, Mengqi Sun, +7 authors, Qingyuan Zhang.
Cancer Manag Res, 2019 Jun 14; 11. PMID: 31191027    Free PMC article.
Radiation myelitis after durvalumab administration following chemoradiotherapy for locally advanced non-small cell lung cancer: an illustrative case report and review of the literature.
Katsumaro Kubo, Koichi Wadasaki, Hiroaki Yamane, Mihoko Doi.
Int Cancer Conf J, 2019 Jun 21; 8(3). PMID: 31218187    Free PMC article.
Acute kidney injury in the patient with cancer.
Mitchell H Rosner, Mark A Perazella.
Kidney Res Clin Pract, 2019 Jul 10; 38(3). PMID: 31284363    Free PMC article.
Review.
Management of Adverse Events in Cancer Patients Treated With PD-1/PD-L1 Blockade: Focus on Asian Populations.
Jiqiao Yang, Xiujing He, +2 authors, Hubing Shi.
Front Pharmacol, 2019 Jul 18; 10. PMID: 31312140    Free PMC article.
Review.
Neutralizing monoclonal antibody against Dickkopf2 impairs lung cancer progression via activating NK cells.
Tianli Shen, Zhengxi Chen, +2 authors, Qian Xiao.
Cell Death Discov, 2019 Aug 03; 5. PMID: 31372243    Free PMC article.
Immune checkpoint inhibitor therapy for pediatric cancers: A mini review of endocrine adverse events.
Kenji Ihara.
Clin Pediatr Endocrinol, 2019 Aug 07; 28(3). PMID: 31384097    Free PMC article.
Relationship of B7-H3 expression in tumor cells and tumor vasculature with FOXP3+ regulatory T cells in renal cell carcinoma.
Kentaro Inamura, Gulanbar Amori, +3 authors, Yuichi Ishikawa.
Cancer Manag Res, 2019 Aug 24; 11. PMID: 31440091    Free PMC article.
OX40 and OX40L protein expression of tumor infiltrating lymphocytes in non-small cell lung cancer and its role in clinical outcome and relationships with other immune biomarkers.
Yayi He, Xiaoshen Zhang, +6 authors, Caicun Zhou.
Transl Lung Cancer Res, 2019 Sep 27; 8(4). PMID: 31555511    Free PMC article.
The association of PD-L1 expression with the efficacy of anti-PD-1/PD-L1 immunotherapy and survival of non-small cell lung cancer patients: a meta-analysis of randomized controlled trials.
Yangyang Xu, Bing Wan, +13 authors, written on behalf of AME Lung Cancer Collaborative Group.
Transl Lung Cancer Res, 2019 Sep 27; 8(4). PMID: 31555516    Free PMC article.
Immunotherapy in urothelial cancer, part 2: adjuvant, neoadjuvant, and adjunctive treatment.
Steven S Yu, Leslie K Ballas, +3 authors, David I Quinn.
Clin Adv Hematol Oncol, 2017 Jul 28; 15(7). PMID: 28749918    Free PMC article.
Review.
Phase I Study of the Bifunctional Fusion Protein Bintrafusp Alfa in Asian Patients with Advanced Solid Tumors, Including a Hepatocellular Carcinoma Safety-Assessment Cohort.
Toshihiko Doi, Yutaka Fujiwara, +5 authors, Masatoshi Kudo.
Oncologist, 2020 Apr 24; 25(9). PMID: 32324927    Free PMC article.
Characterization of a single chain variable fragment of nivolumab that targets PD-1 and blocks PD-L1 binding.
Jong Shin, Paul J Phelan, +2 authors, Peter A Bullock.
Protein Expr Purif, 2020 Sep 29; 177. PMID: 32987122    Free PMC article.
Prognostic value of immune related genes in lung adenocarcinoma.
Han Wang, Meng-Sen Wang, +4 authors, Wen-Jie Wang.
Oncol Lett, 2020 Sep 30; 20(5). PMID: 32989393    Free PMC article.
Hyperprogression: A novel response pattern under immunotherapy.
Xue-Jiao Han, Aqu Alu, +2 authors, Xia-Wei Wei.
Clin Transl Med, 2020 Oct 01; 10(5). PMID: 32997401    Free PMC article.
Review.
Why the Outcome of Anti-Tumor Immune Responses is Heterogeneous: A Novel Idea in the Context of Immunological Heterogeneity in Cancers.
Jing H Wang.
Bioessays, 2020 Aug 09; 42(10). PMID: 32767371    Free PMC article.
TERT mutations correlate with higher TMB value and unique tumor microenvironment and may be a potential biomarker for anti-CTLA4 treatment.
Huahua Li, Jia Li, +2 authors, Haiyong Wang.
Cancer Med, 2020 Aug 19; 9(19). PMID: 32810393    Free PMC article.
Radiation-Induced Enhancement of Antitumor T-cell Immunity by VEGF-Targeted 4-1BB Costimulation.
Brett Schrand, Bhavna Verma, +8 authors, Adrian Ishkanian.
Cancer Res, 2017 Jan 14; 77(6). PMID: 28082399    Free PMC article.
Managing Ipilimumab-Induced Hypophysitis: Challenges and Current Therapeutic Strategies.
Marina Tsoli, Gregory Kaltsas, +3 authors, Eva Kassi.
Cancer Manag Res, 2020 Oct 17; 12. PMID: 33061641    Free PMC article.
Review.
PD-L1 Expression Level Displays a Positive Correlation with Immune Response in Pancreatic Cancer.
Lei Zhao, Yaming Cao.
Dis Markers, 2020 Oct 17; 2020. PMID: 33062072    Free PMC article.
Patient-Derived Tumor Xenograft Models: Toward the Establishment of Precision Cancer Medicine.
Taichiro Goto.
J Pers Med, 2020 Jul 28; 10(3). PMID: 32708458    Free PMC article.
Review.
Cannabis Consumption Used by Cancer Patients during Immunotherapy Correlates with Poor Clinical Outcome.
Gil Bar-Sela, Idan Cohen, +10 authors, David Meiri.
Cancers (Basel), 2020 Sep 03; 12(9). PMID: 32872248    Free PMC article.
CTLA4 has a profound impact on the landscape of tumor-infiltrating lymphocytes with a high prognosis value in clear cell renal cell carcinoma (ccRCC).
Shiyi Liu, Feiyan Wang, +10 authors, Yanxiang Cheng.
Cancer Cell Int, 2020 Oct 30; 20. PMID: 33117084    Free PMC article.
Therapeutic Vaccines for HPV-Associated Malignancies.
Claire Smalley Rumfield, Nicholas Roller, +2 authors, Caroline Jochems.
Immunotargets Ther, 2020 Oct 30; 9. PMID: 33117742    Free PMC article.
Review.
Immunotherapy for Ovarian Cancer: Adjuvant, Combination, and Neoadjuvant.
Chang Yang, Bai-Rong Xia, +3 authors, Wei-Lin Jin.
Front Immunol, 2020 Oct 31; 11. PMID: 33123161    Free PMC article.
Review.
Comprehensive analysis of gene regulation network and immune signatures of prognostic biomarker YAP1 in pancreatic cancer.
Yuan Yang, Ya Zheng, +6 authors, Yongning Zhou.
J Cancer, 2020 Oct 31; 11(23). PMID: 33123286    Free PMC article.
Radiotherapy-Mediated Immunomodulation and Anti-Tumor Abscopal Effect Combining Immune Checkpoint Blockade.
Xinrui Zhao, Chunlin Shao.
Cancers (Basel), 2020 Oct 01; 12(10). PMID: 32992835    Free PMC article.
Review.
Divergent Resistance Mechanisms to Immunotherapy Explain Responses in Different Skin Cancers.
Emmanuel Dollinger, Daniel Bergman, +2 authors, Qing Nie.
Cancers (Basel), 2020 Oct 18; 12(10). PMID: 33065980    Free PMC article.
Serum immune modulators during the first cycle of anti-PD-1 antibody therapy in non-small cell lung cancer: Perforin as a biomarker.
Takayo Ota, Tomoya Fukui, +7 authors, Masahiro Fukuoka.
Thorac Cancer, 2020 Sep 12; 11(11). PMID: 32915511    Free PMC article.
PD-1 inhibitor inducing exosomal miR-34a-5p expression mediates the cross talk between cardiomyocyte and macrophage in immune checkpoint inhibitor-related cardiac dysfunction.
Wenzheng Xia, Hanbin Chen, +3 authors, Meng Hou.
J Immunother Cancer, 2020 Oct 30; 8(2). PMID: 33115945    Free PMC article.
Roles for the FCRL6 Immunoreceptor in Tumor Immunology.
Randall S Davis.
Front Immunol, 2020 Nov 10; 11. PMID: 33162991    Free PMC article.
Review.
Prolonging Survival: The Role of Immune Checkpoint Inhibitors in the Treatment of Extensive-Stage Small Cell Lung Cancer.
Barbara Melosky, Parneet K Cheema, +8 authors, Quincy Chu.
Oncologist, 2020 Aug 30; 25(11). PMID: 32860288    Free PMC article.
Review.
Treatment Sequencing Patterns in Patients with Metastatic Urothelial Cancer Treated in the Community Practice Setting in the United States: SPEAR-Bladder (Study informing treatment Pathway dEcision in bladder cAnceR).
Gurjyot K Doshi, Abhijeet Bhanegaonkar, +6 authors, Hemant Phatak.
Clinicoecon Outcomes Res, 2020 Nov 17; 12. PMID: 33192078    Free PMC article.
Engineered Cell-Membrane-Coated Nanoparticles Directly Present Tumor Antigens to Promote Anticancer Immunity.
Yao Jiang, Nishta Krishnan, +8 authors, Liangfang Zhang.
Adv Mater, 2020 Jun 17; 32(30). PMID: 32538494    Free PMC article.
Fidelity of human ovarian cancer patient-derived xenografts in a partially humanized mouse model for preclinical testing of immunotherapies.
Adekunle Odunsi, A J Robert McGray, +5 authors, Ruea-Yea Huang.
J Immunother Cancer, 2020 Nov 13; 8(2). PMID: 33177175    Free PMC article.
The Expression Pattern and Clinical Significance of the Immune Checkpoint Regulator VISTA in Human Breast Cancer.
Xiaoxue Xie, Junying Zhang, +8 authors, Jun Liu.
Front Immunol, 2020 Dec 01; 11. PMID: 33250890    Free PMC article.
Tumor organoids to study gastroesophageal cancer: a primer.
Ramon U Jin, Jason C Mills.
J Mol Cell Biol, 2020 Jul 12; 12(8). PMID: 32652008    Free PMC article.
Review.
Something in the air: hyperoxic conditioning of the tumor microenvironment for enhanced immunotherapy.
Robert D Leone, Maureen R Horton, Jonathan D Powell.
Cancer Cell, 2015 Apr 16; 27(4). PMID: 25873169    Free PMC article.
Genomic Amplification of CD274 (PD-L1) in Small-Cell Lung Cancer.
Julie George, Motonobu Saito, +15 authors, Takashi Kohno.
Clin Cancer Res, 2016 Sep 14; 23(5). PMID: 27620277    Free PMC article.
Checkpoint Inhibition in Hodgkin Lymphoma: Saving the Best for Last?
Richard J Lin, Catherine S Diefenbach.
Oncology (Williston Park), 2016 Oct 19; 30(10). PMID: 27753058    Free PMC article.
Review.
Immunotherapy for metastatic renal cell carcinoma.
Susanne Unverzagt, Ines Moldenhauer, +5 authors, Barbara Seliger.
Cochrane Database Syst Rev, 2017 May 16; 5. PMID: 28504837    Free PMC article.
Systematic Review.
Common Cardiovascular Complications of Cancer Therapy: Epidemiology, Risk Prediction, and Prevention.
Vivek Narayan, Bonnie Ky.
Annu Rev Med, 2018 Feb 08; 69. PMID: 29414258    Free PMC article.
Review.
Rational design for cervical cancer therapeutics: cellular and non-cellular based strategies on the horizon for recurrent, metastatic or refractory cervical cancer.
Juliet E Wolford, Krishnansu S Tewari.
Expert Opin Drug Discov, 2018 Feb 22; 13(5). PMID: 29463131    Free PMC article.
Review.
Tumor oxygenation and cancer therapy-then and now.
Veronica S Hughes, Jennifer M Wiggins, Dietmar W Siemann.
Br J Radiol, 2018 Mar 08; 92(1093). PMID: 29513032    Free PMC article.
Review.
PD-L1 Immunohistochemistry Assay Concordance in Urothelial Carcinoma of the Bladder and Hypopharyngeal Squamous Cell Carcinoma.
Anjelica Hodgson, Elzbieta Slodkowska, +7 authors, Michelle R Downes.
Am J Surg Pathol, 2018 May 12; 42(8). PMID: 29750666    Free PMC article.
Bugs in the system: bringing the human microbiome to bear in cancer immunotherapy.
Christopher Strouse, Ashutosh Mangalam, Jun Zhang.
Gut Microbes, 2018 Sep 06; 10(2). PMID: 30183502    Free PMC article.
Dynamics of Soluble Programmed Death-Ligand 1 (sPDL1) during Chemotherapy and Its Prognostic Implications in Cancer Patients: Biomarker Development in Immuno-oncology.
Hyerim Ha, Ju-Hee Bang, +4 authors, Do-Youn Oh.
Cancer Res Treat, 2018 Oct 13; 51(2). PMID: 30309223    Free PMC article.
Endocrine and metabolic adverse effects of immune checkpoint inhibitors: an overview (what endocrinologists should know).
R M Ruggeri, A Campennì, +4 authors, S Cannavò.
J Endocrinol Invest, 2018 Nov 25; 42(7). PMID: 30471004
Review.
Translocation-Related Sarcomas.
Kenji Nakano, Shunji Takahashi.
Int J Mol Sci, 2018 Nov 30; 19(12). PMID: 30487384    Free PMC article.
Review.
Combining PARP inhibition, radiation, and immunotherapy: A possible strategy to improve the treatment of cancer?
Mathieu Césaire, Juliette Thariat, +3 authors, François Chevalier.
Int J Mol Sci, 2018 Nov 30; 19(12). PMID: 30487462    Free PMC article.
Review.
Immune checkpoint blockade for Merkel cell carcinoma: actual findings and unanswered questions.
Marco Gallo, Valentina Guarnotta, +4 authors, NIKE Group.
J Cancer Res Clin Oncol, 2019 Jan 09; 145(2). PMID: 30617553
Review.
STAT1 deficiency supports PD-1/PD-L1 signaling resulting in dysfunctional TNFα mediated immune responses in a model of NSCLC.
Juliane Friedrich, Lisanne Heim, +4 authors, Susetta Finotto.
Oncotarget, 2019 Jan 17; 9(98). PMID: 30647851    Free PMC article.
Radiochemotherapy combined with NK cell transfer followed by second-line PD-1 inhibition in a patient with NSCLC stage IIIb inducing long-term tumor control: a case study.
Konrad Kokowski, Stefan Stangl, +3 authors, Gabriele Multhoff.
Strahlenther Onkol, 2019 Feb 13; 195(4). PMID: 30747241    Free PMC article.
MiR-873/PD-L1 axis regulates the stemness of breast cancer cells.
Lanlan Gao, Qianqian Guo, +8 authors, Lufeng Zheng.
EBioMedicine, 2019 Feb 26; 41. PMID: 30803931    Free PMC article.
Highly Cited.
Changes in plasma EBV-DNA and immune status in patients with nasopharyngeal carcinoma after treatment with intensity-modulated radiotherapy.
Qi Chen, Wei Hu, +4 authors, Hongsheng Lu.
Diagn Pathol, 2019 Mar 16; 14(1). PMID: 30871579    Free PMC article.
Role of programmed cell death ligand-1 expression on prognostic and overall survival of breast cancer: A systematic review and meta-analysis.
Shichao Li, Li Chen, Jun Jiang.
Medicine (Baltimore), 2019 Apr 23; 98(16). PMID: 31008945    Free PMC article.
Systematic Review.
Stereotactic Ablative Radiotherapy Combined with Immune Checkpoint Inhibitors Reboots the Immune Response Assisted by Immunotherapy in Metastatic Lung Cancer: A Systematic Review.
Rodolfo Chicas-Sett, Ignacio Morales-Orue, +5 authors, Pedro C Lara.
Int J Mol Sci, 2019 May 06; 20(9). PMID: 31052488    Free PMC article.
Systematic Review.
Risk of dermatologic and mucosal adverse events associated with PD-1/PD-L1 inhibitors in cancer patients: A meta-analysis of randomized controlled trials.
Wenwei Yang, Shuquan Li, Qingrui Yang.
Medicine (Baltimore), 2019 May 18; 98(20). PMID: 31096532    Free PMC article.
PD-L1 is a double-edged sword in colorectal cancer: the prognostic value of PD-L1 depends on the cell type expressing PD-L1.
Hsiang-Ling Ho, Teh-Ying Chou, +4 authors, Hao-Wei Teng.
J Cancer Res Clin Oncol, 2019 May 28; 145(7). PMID: 31129768
Melanoma patients with additional primary cancers: a single-center retrospective analysis.
Florentia Dimitriou, Joanna Mangana, +5 authors, Phil F Cheng.
Oncotarget, 2019 Jun 06; 10(36). PMID: 31164959    Free PMC article.
Human Immune System Increases Breast Cancer-Induced Osteoblastic Bone Growth in a Humanized Mouse Model without Affecting Normal Bone.
Tiina E Kähkönen, Mari I Suominen, +4 authors, Jenni Bernoulli.
J Immunol Res, 2019 Jun 19; 2019. PMID: 31211147    Free PMC article.
Epidermal Growth Factor Receptor (EGFR) Pathway, Yes-Associated Protein (YAP) and the Regulation of Programmed Death-Ligand 1 (PD-L1) in Non-Small Cell Lung Cancer (NSCLC).
Ping-Chih Hsu, David M Jablons, Cheng-Ta Yang, Liang You.
Int J Mol Sci, 2019 Aug 08; 20(15). PMID: 31387256    Free PMC article.
Review.
Immunotherapy-Based Targeting and Elimination of Leukemic Stem Cells in AML and CML.
Peter Valent, Irina Sadovnik, +7 authors, Dominik Wolf.
Int J Mol Sci, 2019 Sep 01; 20(17). PMID: 31470642    Free PMC article.
Review.
Evolution of Genomic and T-cell Repertoire Heterogeneity of Malignant Pleural Mesothelioma Under Dasatinib Treatment.
Runzhe Chen, Won-Chul Lee, +19 authors, Jianjun Zhang.
Clin Cancer Res, 2020 Aug 21; 26(20). PMID: 32816946    Free PMC article.
Immunotherapy with Checkpoint Inhibitors for Hepatocellular Carcinoma: Where Are We Now?
Francesco Tovoli, Stefania De Lorenzo, Franco Trevisani.
Vaccines (Basel), 2020 Oct 08; 8(4). PMID: 33023131    Free PMC article.
Review.
Genomic investigation of co-targeting tumor immune microenvironment and immune checkpoints in pan-cancer immunotherapy.
Xing Huang, Tianyu Tang, +5 authors, Tingbo Liang.
NPJ Precis Oncol, 2020 Dec 11; 4(1). PMID: 33299118    Free PMC article.
Antitumor Drugs and Their Targets.
Zlatko Dembic.
Molecules, 2020 Dec 11; 25(23). PMID: 33297561    Free PMC article.
Review.
Implantable and Injectable Biomaterial Scaffolds for Cancer Immunotherapy.
Jie Li, Yiqian Luo, +3 authors, Changfeng Fu.
Front Bioeng Biotechnol, 2020 Dec 18; 8. PMID: 33330440    Free PMC article.
Review.
TFE3-PD-L1 axis is pivotal for sunitinib resistance in clear cell renal cell carcinoma.
Xudong Guo, Ruxia Li, +2 authors, Hanbo Wang.
J Cell Mol Med, 2020 Nov 05; 24(24). PMID: 33145941    Free PMC article.
Metabolomics to Assess Response to Immune Checkpoint Inhibitors in Patients with Non-Small-Cell Lung Cancer.
Veronica Ghini, Letizia Laera, +6 authors, Daniele Pozzessere.
Cancers (Basel), 2020 Dec 04; 12(12). PMID: 33265926    Free PMC article.
PD-L1 Is a Tumor Suppressor in Aggressive Endometrial Cancer Cells and Its Expression Is Regulated by miR-216a and lncRNA MEG3.
Daozhi Xu, Peixin Dong, +5 authors, Hidemichi Watari.
Front Cell Dev Biol, 2020 Dec 29; 8. PMID: 33363153    Free PMC article.
Durvalumab as third-line or later treatment for advanced non-small-cell lung cancer (ATLANTIC): an open-label, single-arm, phase 2 study.
Marina Chiara Garassino, Byoung-Chul Cho, +16 authors, ATLANTIC Investigators.
Lancet Oncol, 2018 Mar 17; 19(4). PMID: 29545095    Free PMC article.
Highly Cited.
Immune Thrombocytopenia Induced by Immune Checkpoint Inhibitors in Solid Cancer: Case Report and Literature Review.
Xiaolin Liu, Xiuju Liang, +2 authors, Jun Wang.
Front Oncol, 2020 Dec 29; 10. PMID: 33365266    Free PMC article.
Genotyping Squamous Cell Lung Carcinoma in Colombia (Geno1.1-CLICaP).
Andrés F Cardona, Alejandro Ruiz-Patiño, +22 authors, Rafael Rosell.
Front Oncol, 2021 Jan 02; 10. PMID: 33384957    Free PMC article.
Immuno-PET imaging of 68Ga-labeled nanobody Nb109 for dynamic monitoring the PD-L1 expression in cancers.
Qingzhu Liu, Lei Jiang, +4 authors, Ling Qiu.
Cancer Immunol Immunother, 2021 Jan 03; 70(6). PMID: 33386467
Long-Term Gemcitabine Treatment Reshapes the Pancreatic Tumor Microenvironment and Sensitizes Murine Carcinoma to Combination Immunotherapy.
Daniel R Principe, Matthew Narbutis, +12 authors, Ajay Rana.
Cancer Res, 2020 Apr 03; 80(15). PMID: 32238357    Free PMC article.
Ectopic PD-L1 expression in JAK2 (V617F) myeloproliferative neoplasm patients is mediated via increased activation of STAT3 and STAT5.
Sameer Ahamd Guru, Mamta P Sumi, +5 authors, Alpana Saxena.
Hum Cell, 2020 May 21; 33(4). PMID: 32430672
A signature of 17 immune-related gene pairs predicts prognosis and immune status in HNSCC patients.
Pan Jiang, Yanli Li, Zheng Xu, Shengteng He.
Transl Oncol, 2020 Nov 23; 14(1). PMID: 33221687    Free PMC article.
Nivolumab treatment in advanced non-small cell lung cancer: real-world long-term outcomes within overall and special populations (the UNIVOC study).
Jean-Baptiste Assié, Romain Corre, +6 authors, Christos Chouaïd.
Ther Adv Med Oncol, 2021 Jan 07; 12. PMID: 33403011    Free PMC article.
Recent Advances in the Development of TGF-β Signaling Inhibitors for Anticancer Therapy.
Ho-Jae Lee.
J Cancer Prev, 2021 Jan 08; 25(4). PMID: 33409254    Free PMC article.
Review.
Continuous monitoring of neutrophils to lymphocytes ratio for estimating the onset, severity, and subsequent prognosis of immune related adverse events.
Ryosuke Matsukane, Hiroyuki Watanabe, +11 authors, Nobuaki Egashira.
Sci Rep, 2021 Jan 16; 11(1). PMID: 33446685    Free PMC article.
DNA methylation-based lung adenocarcinoma subtypes can predict prognosis, recurrence, and immunotherapeutic implications.
Feng Xu, Lulu He, +7 authors, Yongsong Chen.
Aging (Albany NY), 2020 Nov 26; 12(24). PMID: 33234739    Free PMC article.
Bioinformatics analysis identifies COL1A1, THBS2 and SPP1 as potential predictors of patient prognosis and immunotherapy response in gastric cancer.
Yali Wang, Kun Zheng, +2 authors, Yanmei Zou.
Biosci Rep, 2020 Dec 22; 41(1). PMID: 33345281    Free PMC article.
Synthesis of DOTA-pyridine chelates for 64Cu coordination and radiolabeling of αMSH peptide.
Hua Yang, Feng Gao, +8 authors, Paul Schaffer.
EJNMMI Radiopharm Chem, 2021 Jan 14; 6(1). PMID: 33438075    Free PMC article.
Current concept for tertiary lymphoid structures in urothelial carcinoma of the bladder: a literature review and our experience.
Milena Gulinac, Dorian Dikov, Simeon Lichev, Tsvetelina Velikova.
Am J Clin Exp Immunol, 2021 Jan 26; 9(5). PMID: 33489474    Free PMC article.
Review.
VISTA Expression on Immune Cells Correlates With Favorable Prognosis in Patients With Triple-Negative Breast Cancer.
Xi Cao, Xinyu Ren, +4 authors, Qiang Sun.
Front Oncol, 2021 Jan 29; 10. PMID: 33505908    Free PMC article.
Determining Factors in the Therapeutic Success of Checkpoint Immunotherapies against PD-L1 in Breast Cancer: A Focus on Epithelial-Mesenchymal Transition Activation.
Mariana Segovia-Mendoza, Susana Romero-Garcia, Cristina Lemini, Heriberto Prado-Garcia.
J Immunol Res, 2021 Jan 29; 2021. PMID: 33506060    Free PMC article.
Review.
Data-Driven Methods for Advancing Precision Oncology.
Prema Nedungadi, Akshay Iyer, +2 authors, Asha B Pillai.
Curr Pharmacol Rep, 2018 Apr 01; 4(2). PMID: 33520605    Free PMC article.
Mesenchymal traits at the convergence of tumor-intrinsic and -extrinsic mechanisms of resistance to immune checkpoint blockers.
Paola Trono, Antonella Sistigu, +2 authors, Paola Nisticò.
Emerg Top Life Sci, 2017 Dec 12; 1(5). PMID: 33525801    Free PMC article.
The MAPK hypothesis: immune-regulatory effects of MAPK-pathway genetic dysregulations and implications for breast cancer immunotherapy.
Davide Bedognetti, Jessica Roelands, +2 authors, Wouter Hendrickx.
Emerg Top Life Sci, 2017 Dec 12; 1(5). PMID: 33525803    Free PMC article.
Peripheral T cell receptor repertoire features predict durable responses to anti-PD-1 inhibitor monotherapy in advanced renal cell carcinoma.
Taigo Kato, Kazuma Kiyotani, +12 authors, Motohide Uemura.
Oncoimmunology, 2021 Feb 05; 10(1). PMID: 33537170    Free PMC article.
NLRC5/CITA expression correlates with efficient response to checkpoint blockade immunotherapy.
Sayuri Yoshihama, Steven X Cho, +5 authors, Koichi S Kobayashi.
Sci Rep, 2021 Feb 07; 11(1). PMID: 33547395    Free PMC article.
Immunotherapeutic strategies in breast cancer: A clinical update.
Jennifer Q Zhang, George Plitas.
J Surg Oncol, 2020 Nov 07; 123(3). PMID: 33155281    Free PMC article.
Review.
Life and Death Decision-Making by p53 and Implications for Cancer Immunotherapy.
Yong Liu, Patrick L Leslie, Yanping Zhang.
Trends Cancer, 2020 Nov 18; 7(3). PMID: 33199193    Free PMC article.
Review.
A T cell repertoire timestamp is at the core of responsiveness to CTLA-4 blockade.
Hagit Philip, Tom Snir, +3 authors, Sol Efroni.
iScience, 2021 Feb 20; 24(2). PMID: 33604527    Free PMC article.
Advantages of targeting the tumor immune microenvironment over blocking immune checkpoint in cancer immunotherapy.
Tianyu Tang, Xing Huang, +3 authors, Tingbo Liang.
Signal Transduct Target Ther, 2021 Feb 21; 6(1). PMID: 33608497    Free PMC article.
Review.
Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma.
Yixiao Qin, Xiwang Zheng, +2 authors, Yongyan Wu.
Mol Ther Oncolytics, 2021 Feb 23; 20. PMID: 33614915    Free PMC article.
Review.
Monophosphoryl lipid A-induced activation of plasmacytoid dendritic cells enhances the anti-cancer effects of anti-PD-L1 antibodies.
Wei Zhang, Seong-Min Lim, +3 authors, Jun-O Jin.
Cancer Immunol Immunother, 2020 Sep 10; 70(3). PMID: 32902663
Response to Treatment with an Anti-Interleukin-6 Receptor Antibody (Tocilizumab) in a Patient with Hemophagocytic Syndrome Secondary to Immune Checkpoint Inhibitors.
Alejandro Olivares-Hernández, Luis Figuero-Pérez, +7 authors, Juan Jesús Cruz Hernández.
Case Rep Oncol Med, 2021 Feb 26; 2021. PMID: 33628551    Free PMC article.
The Role of Immunotherapy in the Treatment of Adrenocortical Carcinoma.
Izabela Karwacka, Łukasz Obołończyk, Sonia Kaniuka-Jakubowska, Krzysztof Sworczak.
Biomedicines, 2021 Jan 28; 9(2). PMID: 33498467    Free PMC article.
Review.
Recent Advancements in the Mechanisms Underlying Resistance to PD-1/PD-L1 Blockade Immunotherapy.
Yu Yuan, Abdalla Adam, Chen Zhao, Honglei Chen.
Cancers (Basel), 2021 Feb 11; 13(4). PMID: 33562324    Free PMC article.
Review.
Lights and Shadows in Immuno-Oncology Drug Development.
Milana Bergamino Sirvén, Sonia Pernas, Maggie C U Cheang.
Cancers (Basel), 2021 Feb 13; 13(4). PMID: 33572060    Free PMC article.
International Consensus Guidance for Management of Myasthenia Gravis: 2020 Update.
Pushpa Narayanaswami, Donald B Sanders, +13 authors, Jan Verschuuren.
Neurology, 2020 Nov 05; 96(3). PMID: 33144515    Free PMC article.
Review.
Combination of echocardiography and emergency endomyocardial biopsy for suspected myocarditis in the cardiovascular emergency medical care.
Hirohide Matsuura, Nozomi Watanabe, Yoshisato Shibata, Yujiro Asada.
J Echocardiogr, 2021 Mar 05; 19(2). PMID: 33661474
Review.
Actinidia eriantha Polysaccharide and PD1-Antibody Combination Therapy Enhances Antitumor Efficacy in Colorectal Cancer-Xenograft Mice.
Jinxia Li, Yiping Wang, Weiyang Jin, Li Shen.
Onco Targets Ther, 2021 Mar 05; 14. PMID: 33658792    Free PMC article.
Involvement of Cellular Prion Protein in Invasion and Metastasis of Lung Cancer by Inducing Treg Cell Development.
Seunghwa Cha, Mi-Ji Sin, +4 authors, Mi-Yeon Kim.
Biomolecules, 2021 Mar 07; 11(2). PMID: 33671884    Free PMC article.
Immune Checkpoint Inhibition in Oesophago-Gastric Carcinoma.
Anica Högner, Peter Thuss-Patience.
Pharmaceuticals (Basel), 2021 Mar 07; 14(2). PMID: 33673374    Free PMC article.
Review.
Beyond immune checkpoint blockade: emerging immunological strategies.
Shawn P Kubli, Thorsten Berger, +2 authors, Tak W Mak.
Nat Rev Drug Discov, 2021 Mar 10; 20(12). PMID: 33686237
Review.
Therapeutic Time-restricted Feeding Reduces Renal Tumor Bioluminescence in Mice but Fails to Improve Anti-CTLA-4 Efficacy.
William J Turbitt, Rachael M Orlandella, +2 authors, Lyse A Norian.
Anticancer Res, 2020 Sep 30; 40(10). PMID: 32988866    Free PMC article.
Association of Survival and Immune-Related Adverse Events With Anti-PD-1/PD-L1 and Anti-CTLA-4 Inhibitors, Alone or Their Combination for the Treatment of Cancer: A Systematic Review and Meta-Analysis of 13 Clinical Trials.
Leyin Zhang, Leitao Sun, +5 authors, Shanming Ruan.
Front Oncol, 2021 Mar 16; 11. PMID: 33718135    Free PMC article.
Systematic Review.
TIM-3 levels correlate with enhanced NK cell cytotoxicity and improved clinical outcome in AML patients.
Jana Rakova, Iva Truxova, +12 authors, Jitka Fucikova.
Oncoimmunology, 2021 Mar 25; 10(1). PMID: 33758676    Free PMC article.
The Mechanisms Leading to Distinct Responses to PD-1/PD-L1 Blockades in Colorectal Cancers With Different MSI Statuses.
Guanglin Cui.
Front Oncol, 2021 Mar 26; 11. PMID: 33763344    Free PMC article.
Review.
Treatment- and immune-related adverse events of immune checkpoint inhibitors in advanced lung cancer.
Jun Shao, Chengdi Wang, +3 authors, Weimin Li.
Biosci Rep, 2020 Apr 22; 40(5). PMID: 32315071    Free PMC article.
Systematic Review.
Host response to immune checkpoint inhibitors contributes to tumor aggressiveness.
Irina Khononov, Eyal Jacob, +5 authors, Yuval Shaked.
J Immunother Cancer, 2021 Mar 13; 9(3). PMID: 33707313    Free PMC article.
Refractory Bullous Pemphigoid in a Patient with Metastatic Lung Adenocarcinoma Treated with Pembrolizumab.
Andrés F Cardona, Alejandro Ruiz-Patiño, +4 authors, Oscar Arrieta.
Case Rep Oncol, 2021 Mar 30; 14(1). PMID: 33776733    Free PMC article.
Imaging-based Biomarkers for Predicting and Evaluating Cancer Immunotherapy Response.
Minghao Wu, Yanyan Zhang, +3 authors, Zhaoxiang Ye.
Radiol Imaging Cancer, 2019 Nov 29; 1(2). PMID: 33778682    Free PMC article.
Review.
Characterizing the molecular regulation of inhibitory immune checkpoints with multimodal single-cell screens.
Efthymia Papalexi, Eleni P Mimitou, +8 authors, Rahul Satija.
Nat Genet, 2021 Mar 03; 53(3). PMID: 33649593    Free PMC article.
Immunotherapy as a treatment strategy in advanced stage and recurrent endometrial cancer: review of current phase III immunotherapy clinical trials.
Ramez N Eskander, Matthew A Powell.
Ther Adv Med Oncol, 2021 Apr 03; 13. PMID: 33796152    Free PMC article.
Review.
Polysaccharide-based nanomedicines for cancer immunotherapy: A review.
Yujun Zeng, Yufan Xiang, +6 authors, Kui Luo.
Bioact Mater, 2021 Apr 06; 6(10). PMID: 33817416    Free PMC article.
Review.
Talimogene Laherparepvec (T-VEC): An Intralesional Cancer Immunotherapy for Advanced Melanoma.
Pier Francesco Ferrucci, Laura Pala, Fabio Conforti, Emilia Cocorocchio.
Cancers (Basel), 2021 Apr 04; 13(6). PMID: 33803762    Free PMC article.
Review.
Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy.
Antoni Ribas, Reinhard Dummer, +17 authors, Georgina V Long.
Cell, 2017 Sep 09; 170(6). PMID: 28886381    Free PMC article.
Highly Cited.
Recent Progress in the Synergistic Combination of Nanoparticle-Mediated Hyperthermia and Immunotherapy for Treatment of Cancer.
Zachary R Stephen, Miqin Zhang.
Adv Healthc Mater, 2020 Nov 26; 10(2). PMID: 33236511    Free PMC article.
Review.
New Studies of Pathogenesis of Rheumatoid Arthritis with Collagen-Induced and Collagen Antibody-Induced Arthritis Models: New Insight Involving Bacteria Flora.
Ryoichi Hashida, Yasunori Shimozuru, +3 authors, Kuniaki Terato.
Autoimmune Dis, 2021 Apr 10; 2021. PMID: 33833871    Free PMC article.
Review.
Establishment and validation of a prognostic signature for lung adenocarcinoma based on metabolism-related genes.
Zhihao Wang, Kidane Siele Embaye, +7 authors, Shenghui Qin.
Cancer Cell Int, 2021 Apr 17; 21(1). PMID: 33858449    Free PMC article.
Cellular networks controlling T cell persistence in adoptive cell therapy.
Jack D Chan, Junyun Lai, +3 authors, Phillip K Darcy.
Nat Rev Immunol, 2021 Apr 22; 21(12). PMID: 33879873
Review.
Curative-Intent Treatment with Durvalumab in Early-Stage Cancers.
Giovanni Melillo, Vikram Chand, +2 authors, Cristian Massacesi.
Adv Ther, 2021 Apr 22; 38(6). PMID: 33881745    Free PMC article.
Review.
Intrinsic and acquired resistance to CDK4/6 inhibitors and potential overcoming strategies.
Xia-Qing Xu, Xiao-Hui Pan, +4 authors, Ling Ding.
Acta Pharmacol Sin, 2020 Jun 07; 42(2). PMID: 32504067    Free PMC article.
Review.
Efficacy of Paclitaxel-based Chemotherapy After Progression on Nivolumab for Head and Neck Cancer.
Yasuyoshi Sato, Naoki Fukuda, +8 authors, Shunji Takahashi.
In Vivo, 2021 Feb 25; 35(2). PMID: 33622923    Free PMC article.
AFP-Inhibiting Fragments for Drug Delivery: The Promise and Challenges of Targeting Therapeutics to Cancers.
Bo Lin, Xu Dong, +3 authors, Mengsen Li.
Front Cell Dev Biol, 2021 Apr 27; 9. PMID: 33898423    Free PMC article.
Review.
Clinicopathological analysis of hepatic immune-related adverse events in comparison with autoimmune hepatitis and graft-versus host disease.
Satoru Hagiwara, Tomohiro Watanabe, +15 authors, Naoshi Nishida.
Sci Rep, 2021 May 01; 11(1). PMID: 33927311    Free PMC article.
Tumor microenvironment as a therapeutic target in cancer.
Yi Xiao, Dihua Yu.
Pharmacol Ther, 2020 Dec 02; 221. PMID: 33259885    Free PMC article.
Review.
Pancreatic Cancer Signaling Pathways, Genetic Alterations, and Tumor Microenvironment: The Barriers Affecting the Method of Treatment.
Darya Javadrashid, Amir Baghbanzadeh, +5 authors, Behzad Baradaran.
Biomedicines, 2021 May 01; 9(4). PMID: 33918146    Free PMC article.
Review.
Immune Checkpoints, Inhibitors and Radionuclides in Prostate Cancer: Promising Combinatorial Therapy Approach.
Mankgopo M Kgatle, Tebatso M G Boshomane, +7 authors, Mike M Sathekge.
Int J Mol Sci, 2021 May 01; 22(8). PMID: 33921181    Free PMC article.
Review.
Infiltration of Immune Competent Cells into Primary Tumors and Their Surrounding Connective Tissues in Xenograft and Syngeneic Mouse Models.
Marlon Metzen, Michael Bruns, Wolfgang Deppert, Udo Schumacher.
Int J Mol Sci, 2021 May 01; 22(8). PMID: 33921688    Free PMC article.
Liquid Biopsies in Solid Cancers: Implementation in a Nordic Healthcare System.
Oddmund Nordgård, Rakel Brendsdal Forthun, +8 authors, Randi Hovland.
Cancers (Basel), 2021 May 01; 13(8). PMID: 33924696    Free PMC article.
Review.
The Cancer Cell Dissemination Machinery as an Immunosuppressive Niche: A New Obstacle Towards the Era of Cancer Immunotherapy.
Saeed Asiry, Gina Kim, +5 authors, George S Karagiannis.
Front Immunol, 2021 May 01; 12. PMID: 33927723    Free PMC article.
Review.
The cancer-natural killer cell immunity cycle.
Nicholas D Huntington, Joseph Cursons, Jai Rautela.
Nat Rev Cancer, 2020 Jun 26; 20(8). PMID: 32581320
Review.
Clinical implications of bronchoscopy for immune checkpoint inhibitor-related pneumonitis in patients with non-small cell lung cancer.
Osamu Nishiyama, Shigeki Shimizu, +9 authors, Yuji Tohda.
BMC Pulm Med, 2021 May 10; 21(1). PMID: 33964920    Free PMC article.
Andrographolide Against Lung Cancer-New Pharmacological Insights Based on High-Throughput Metabolomics Analysis Combined with Network Pharmacology.
Wen Luo, Li Jia, +3 authors, Wei Zhang.
Front Pharmacol, 2021 May 11; 12. PMID: 33967748    Free PMC article.
Categorisation of patients based on immune profiles: a new approach to identifying candidates for response to checkpoint inhibitors.
Svetlana Bornschlegl, Michael P Gustafson, +9 authors, Allan B Dietz.
Clin Transl Immunology, 2021 May 11; 10(4). PMID: 33968403    Free PMC article.
Immunotherapy for pancreatic cancer.
Jai Hoon Yoon, Ye-Ji Jung, Sung-Hoon Moon.
World J Clin Cases, 2021 May 11; 9(13). PMID: 33969083    Free PMC article.
Review.
Therapeutic potential of interleukin-15 in cancer (Review).
Gheorghita Isvoranu, Mihaela Surcel, +4 authors, Marioara Chiritoiu-Butnaru.
Exp Ther Med, 2021 May 15; 22(1). PMID: 33986840    Free PMC article.
Review.
Nephrotoxicity as a Complication of Chemotherapy and Immunotherapy in the Treatment of Colorectal Cancer, Melanoma and Non-Small Cell Lung Cancer.
Joanna Jagieła, Piotr Bartnicki, Jacek Rysz.
Int J Mol Sci, 2021 May 01; 22(9). PMID: 33924827    Free PMC article.
Review.
Analysis of the tumor microenvironment and anti-tumor efficacy of subcutaneous vs systemic delivery of the bifunctional agent bintrafusp alfa.
Yohei Ozawa, Kristin C Hicks, +3 authors, Sofia R Gameiro.
Oncoimmunology, 2021 May 18; 10(1). PMID: 33996267    Free PMC article.
[Chinese Experts Consensus on Immune Checkpoint Inhibitors 
for Non-small Cell Lung Cancer (2020 Version)].
Caicun Zhou, Jie Wang, +22 authors, Shukui Qin.
Zhongguo Fei Ai Za Zhi, 2021 Apr 26; 24(4). PMID: 33896153    Free PMC article.
Identification of CTLA-4-Positive Cells in the Human Tonsil.
Markus Tiemann, Dmitri Atiakshin, Vera Samoilova, Igor Buchwalow.
Cells, 2021 May 01; 10(5). PMID: 33925389    Free PMC article.
Identification of combinations of somatic mutations that predict cancer survival and immunotherapy benefit.
Ayal B Gussow, Eugene V Koonin, Noam Auslander.
NAR Cancer, 2021 May 25; 3(2). PMID: 34027407    Free PMC article.
Development and Validation of a CD8+ T Cell Infiltration-Related Signature for Melanoma Patients.
Yuan Yuan, Zheng Zhu, +8 authors, Zewen Song.
Front Immunol, 2021 May 28; 12. PMID: 34040608    Free PMC article.
Immune-related cutaneous adverse events due to checkpoint inhibitors.
Evelyn Wang, Lukas Kraehenbuehl, +3 authors, Donald Y M Leung.
Ann Allergy Asthma Immunol, 2021 Feb 21; 126(6). PMID: 33609771    Free PMC article.
Review.
Age-Associated Changes in Adverse Events Arising From Anti-PD-(L)1 Therapy.
Xinyi Huang, Tiantian Tian, +3 authors, Jiandong Zhang.
Front Oncol, 2021 Jun 01; 11. PMID: 34055598    Free PMC article.
Sepsis-Pathophysiology and Therapeutic Concepts.
Dominik Jarczak, Stefan Kluge, Axel Nierhaus.
Front Med (Lausanne), 2021 Jun 01; 8. PMID: 34055825    Free PMC article.
Review.
Anti-pituitary antibodies and susceptible human leukocyte antigen alleles as predictive biomarkers for pituitary dysfunction induced by immune checkpoint inhibitors.
Tomoko Kobayashi, Shintaro Iwama, +13 authors, Hiroshi Arima.
J Immunother Cancer, 2021 May 21; 9(5). PMID: 34011534    Free PMC article.
Nanotechnology synergized immunoengineering for cancer.
Deepak S Chauhan, Anupam Dhasmana, +6 authors, Murali M Yallapu.
Eur J Pharm Biopharm, 2021 Mar 29; 163. PMID: 33774162    Free PMC article.
Review.
Diet-Induced Obesity Impairs Outcomes and Induces Multi-Factorial Deficiencies in Effector T Cell Responses Following Anti-CTLA-4 Combinatorial Immunotherapy in Renal Tumor-Bearing Mice.
William J Turbitt, Shannon K Boi, +2 authors, Lyse A Norian.
Cancers (Basel), 2021 Jun 03; 13(10). PMID: 34064933    Free PMC article.
Immune Check-Point Inhibitors and Standard Chemoradiotherapy in Definitive Head and Neck Cancer Treatment.
Francesca De Felice, Daniela Musio, Vincenzo Tombolini.
J Pers Med, 2021 Jun 03; 11(5). PMID: 34068797    Free PMC article.
Review.
Potential Role of Hsp70 and Activated NK Cells for Prediction of Prognosis in Glioblastoma Patients.
Dominik Lobinger, Jens Gempt, +15 authors, Gabriele Multhoff.
Front Mol Biosci, 2021 Jun 04; 8. PMID: 34079819    Free PMC article.
Association of immune-related adverse events induced by nivolumab with a battery of autoantibodies.
Iñigo Les, Mireia Martínez, +7 authors, Severina Domínguez.
Ann Med, 2021 Jun 02; 53(1). PMID: 34060971    Free PMC article.
Inflammation-Induced Tumorigenesis and Metastasis.
Sana Hibino, Tetsuro Kawazoe, +4 authors, Koji Taniguchi.
Int J Mol Sci, 2021 Jun 03; 22(11). PMID: 34063828    Free PMC article.
Review.
Dermatologic Toxicities of Targeted Therapy and Immunotherapy in Head and Neck Cancers.
Maria L Espinosa, Chelsea Abad, Yaira Kurtzman, Farah R Abdulla.
Front Oncol, 2021 Jun 15; 11. PMID: 34123780    Free PMC article.
Review.
Identification of a 15-pseudogene based prognostic signature for predicting survival and antitumor immune response in breast cancer.
Liqiang Tan, Xiaofang He, Guoping Shen.
Aging (Albany NY), 2020 Dec 31; 13(10). PMID: 33378744    Free PMC article.
Excellent Response to Atezolizumab After Clinically Defined Hyperprogression Upon Previous Treatment With Pembrolizumab in Metastatic Triple-Negative Breast Cancer: A Case Report and Review of the Literature.
Dongfeng Feng, Yaping Guan, +6 authors, Jun Wang.
Front Immunol, 2021 Jun 18; 12. PMID: 34135884    Free PMC article.
Review.
The Potential Role of the Intestinal Micromilieu and Individual Microbes in the Immunobiology of Chimeric Antigen Receptor T-Cell Therapy.
Maria-Luisa Schubert, Roman Rohrbach, Michael Schmitt, Christoph K Stein-Thoeringer.
Front Immunol, 2021 Jun 18; 12. PMID: 34135898    Free PMC article.
Review.
An Antigen-Delivery Protein Nanoparticle Combined with Anti-PD-1 Checkpoint Inhibitor Has Curative Efficacy in an Aggressive Melanoma Model.
Medea Neek, Jo Anne Tucker, +2 authors, Szu-Wen Wang.
Adv Ther (Weinh), 2021 Jun 19; 3(12). PMID: 34141865    Free PMC article.
T-cell responses and combined immunotherapy against human carbonic anhydrase 9-expressing mouse renal cell carcinoma.
Mamoru Harada, Yuichi Iida, +5 authors, Hirotsugu Uemura.
Cancer Immunol Immunother, 2021 Jun 24; 71(2). PMID: 34160685
Phase I study of pucotenlimab (HX008), an anti-PD-1 antibody, for patients with advanced solid tumors.
Rujiao Liu, Wenhua Li, +3 authors, Xichun Hu.
Ther Adv Med Oncol, 2021 Jun 24; 13. PMID: 34158838    Free PMC article.
An Emergent Form of Cardiotoxicity: Acute Myocarditis Induced by Immune Checkpoint Inhibitors.
Roberta Esposito, Teresa Fedele, +8 authors, Giovanni Esposito.
Biomolecules, 2021 Jun 03; 11(6). PMID: 34067474    Free PMC article.
Review.
Dynamic Collaborations for the Development of Immune Checkpoint Blockade Agents.
Arisa Djurian, Tomohiro Makino, +2 authors, Kota Kodama.
J Pers Med, 2021 Jun 03; 11(6). PMID: 34073680    Free PMC article.
Blockade of checkpoint receptor PVRIG unleashes anti-tumor immunity of NK cells in murine and human solid tumors.
Yangyang Li, Yu Zhang, +7 authors, Haoyu Sun.
J Hematol Oncol, 2021 Jun 28; 14(1). PMID: 34174928    Free PMC article.
Expression and Prognostic Significance of PD-L2 in Diffuse Large B-Cell Lymphoma.
Qianhui Gu, Jing Li, +6 authors, Song He.
Front Oncol, 2021 Jun 29; 11. PMID: 34178648    Free PMC article.
[Prevalence and treatment of rheumatological adverse events due to immune checkpoint inhibitor therapy].
S H Verspohl, H Schulze-Koops, A Heine, V S Schäfer.
Z Rheumatol, 2020 Sep 15; 79(8). PMID: 32926217
Review.
Recent Advances on Immune Targeted Therapy of Colorectal Cancer Using bi-Specific Antibodies and Therapeutic Vaccines.
Ali Azadi, Alireza Golchini, +4 authors, Shirin Eyvazi.
Biol Proced Online, 2021 Jul 02; 23(1). PMID: 34193050    Free PMC article.
Review.
Immunogenomics in personalized cancer treatments.
Kazuma Kiyotani, Yujiro Toyoshima, Yusuke Nakamura.
J Hum Genet, 2021 Jul 02; 66(9). PMID: 34193979
Review.
Rheumatic Immune-Related Adverse Events-A Consequence of Immune Checkpoint Inhibitor Therapy.
Anca Bobircă, Florin Bobircă, +6 authors, Anca Emanuela Mușetescu.
Biology (Basel), 2021 Jul 03; 10(6). PMID: 34203101    Free PMC article.
Review.
Multidiscipline Immunotherapy-Based Rational Combinations for Robust and Durable Efficacy in Brain Metastases from Renal Cell Carcinoma.
Hye-Won Lee.
Int J Mol Sci, 2021 Jul 03; 22(12). PMID: 34208157    Free PMC article.
Review.
Prognostic impact of immune-related adverse events on patients with and without cardiovascular disease: a retrospective review.
Shingo Kazama, Ryota Morimoto, +15 authors, Toyoaki Murohara.
Cardiooncology, 2021 Jul 08; 7(1). PMID: 34229760    Free PMC article.
Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events.
Julie R Brahmer, Hamzah Abu-Sbeih, +20 authors, Marc S Ernstoff.
J Immunother Cancer, 2021 Jun 27; 9(6). PMID: 34172516    Free PMC article.
Neoadjuvant immunotherapy for resectable non-small cell lung cancer.
Hui Xie, Xuejun Shi, Guangshun Wang.
Am J Cancer Res, 2021 Jul 13; 11(6). PMID: 34249414    Free PMC article.
Review.
The evolving role of immunotherapy in prostate cancer.
Lisa M Cordes, James L Gulley, Ravi A Madan.
Curr Opin Oncol, 2016 Mar 16; 28(3). PMID: 26977847    Free PMC article.
Review.
Combination Therapies for HPV-Associated Malignancies.
Claire Smalley Rumfield, Jeffrey Schlom, Caroline Jochems.
J Clin Cell Immunol, 2021 Jul 16; 12(1). PMID: 34262794    Free PMC article.
Pericardial Toxicities Associated With Immune Checkpoint Inhibitors: A Pharmacovigilance Analysis of the FDA Adverse Event Reporting System (FAERS) Database.
Zhuo Ma, Jie Pei, +7 authors, Zhixia Zhao.
Front Pharmacol, 2021 Jul 20; 12. PMID: 34276364    Free PMC article.
Prognostic Value of Tumor-Infiltrating Lymphocytes and Tertiary Lymphoid Structures in Epstein-Barr Virus-Associated and -Negative Gastric Carcinoma.
Na Cheng, Peng Li, +6 authors, Chunkui Shao.
Front Immunol, 2021 Jul 20; 12. PMID: 34276684    Free PMC article.
Clinical and immunologic implications of COVID-19 in patients with melanoma and renal cell carcinoma receiving immune checkpoint inhibitors.
Benjamin Switzer, John Haanen, +2 authors, Samra Turajlic.
J Immunother Cancer, 2021 Jul 18; 9(7). PMID: 34272309    Free PMC article.
Review.
Bioengineering tools for probing intracellular events in T lymphocytes.
Xinyuan Zhang, Chelsea F Mariano, Yuta Ando, Keyue Shen.
WIREs Mech Dis, 2020 Oct 20; 13(4). PMID: 33073545    Free PMC article.
Review.
Holding our breath: the promise of tissue-resident memory T cells in lung cancer.
Claire Marceaux, Clare E Weeden, Claire L Gordon, Marie-Liesse Asselin-Labat.
Transl Lung Cancer Res, 2021 Jul 24; 10(6). PMID: 34295680    Free PMC article.
Review.
Immunotherapy and Vaccination in Surgically Resectable Non-Small Cell Lung Cancer (NSCLC).
Li-Chung Chiu, Shu-Min Lin, +3 authors, Ping-Chih Hsu.
Vaccines (Basel), 2021 Jul 03; 9(7). PMID: 34201650    Free PMC article.
Review.
Silibinin Regulates Tumor Progression and Tumorsphere Formation by Suppressing PD-L1 Expression in Non-Small Cell Lung Cancer (NSCLC) Cells.
Alexis Rugamba, Dong Young Kang, +4 authors, Kyoung-Jin Jang.
Cells, 2021 Jul 03; 10(7). PMID: 34209829    Free PMC article.
Combination Foretinib and Anti-PD-1 Antibody Immunotherapy for Colorectal Carcinoma.
Yuyin Fu, Yujia Peng, +16 authors, Jinliang Yang.
Front Cell Dev Biol, 2021 Jul 27; 9. PMID: 34307367    Free PMC article.
Integrative and Comprehensive Pancancer Analysis of Regulator of Chromatin Condensation 1 (RCC1).
Changwu Wu, Yingjuan Duan, +3 authors, Georg Osterhoff.
Int J Mol Sci, 2021 Jul 25; 22(14). PMID: 34298996    Free PMC article.
Prognostic significance of pre-treatment ALBI grade in advanced non-small cell lung cancer receiving immune checkpoint therapy.
Ryosuke Matsukane, Hiroyuki Watanabe, +6 authors, Ichiro Ieiri.
Sci Rep, 2021 Jul 25; 11(1). PMID: 34301991    Free PMC article.
Genetic evidence for the causal association between programmed death-ligand 1 and lung cancer.
Zhao Yang, Rong Yu, Wei Deng, Weihu Wang.
J Cancer Res Clin Oncol, 2021 Jul 30; 147(11). PMID: 34324065
Integrated imaging and molecular analysis to decipher tumor microenvironment in the era of immunotherapy.
Jia Wu, Aaron T Mayer, Ruijiang Li.
Semin Cancer Biol, 2020 Dec 09;. PMID: 33290844    Free PMC article.
Current Trends of Immunotherapy in the Treatment of Cutaneous Melanoma: A Review.
Piyu Parth Naik.
Dermatol Ther (Heidelb), 2021 Aug 03; 11(5). PMID: 34339016    Free PMC article.
Review.
Tumor microenvironment and immune evasion in head and neck squamous cell carcinoma.
Areeg Elmusrati, Justin Wang, Cun-Yu Wang.
Int J Oral Sci, 2021 Aug 04; 13(1). PMID: 34341329    Free PMC article.
Review.
Antigen Delivery to DEC205+ Dendritic Cells Induces Immunological Memory and Protective Therapeutic Effects against HPV-Associated Tumors at Different Anatomical Sites.
Mariângela O Silva, Bianca S Almeida, +9 authors, Luís C S Ferreira.
Int J Biol Sci, 2021 Aug 05; 17(11). PMID: 34345218    Free PMC article.
Effects of concomitant proton pump inhibitor use on immune checkpoint inhibitor efficacy among patients with advanced cancer.
Bao-Dong Qin, Xiao-Dong Jiao, +6 authors, Yuan-Sheng Zang.
Oncoimmunology, 2021 Aug 06; 10(1). PMID: 34350061    Free PMC article.
CD8+ T Cell Exhaustion in Cancer.
Joseph S Dolina, Natalija Van Braeckel-Budimir, Graham D Thomas, Shahram Salek-Ardakani.
Front Immunol, 2021 Aug 07; 12. PMID: 34354714    Free PMC article.
Review.
Comparing syngeneic and autochthonous models of breast cancer to identify tumor immune components that correlate with response to immunotherapy in breast cancer.
Jessica Castrillon Lal, Madeline G Townsend, +7 authors, Jennifer L Guerriero.
Breast Cancer Res, 2021 Aug 07; 23(1). PMID: 34353349    Free PMC article.
Treatment of Hepatocellular Carcinoma with Immune Checkpoint Inhibitors and Applicability of First-Line Atezolizumab/Bevacizumab in a Real-Life Setting.
Maria Corina Plaz Torres, Quirino Lai, +7 authors, Edoardo G Giannini.
J Clin Med, 2021 Aug 08; 10(15). PMID: 34361985    Free PMC article.
Review.
Musculoskeletal adverse reactions after immunotherapy for cancer: A case series.
Ioana Creţu, Mihai Bojincă, +7 authors, Ruxandra Ionescu.
Exp Ther Med, 2021 Aug 11; 22(3). PMID: 34373713    Free PMC article.
Isolated adrenocorticotropic hormone (ACTH) deficiency and Guillain-Barré syndrome occurring in a patient treated with nivolumab.
Julien Pierrard, Bénédicte Petit, Sarah Lejeune, Emmanuel Seront.
BMJ Case Rep, 2019 Aug 24; 12(8). PMID: 31439558    Free PMC article.
Technological advances in cancer immunity: from immunogenomics to single-cell analysis and artificial intelligence.
Ying Xu, Guan-Hua Su, +3 authors, Yi-Zhou Jiang.
Signal Transduct Target Ther, 2021 Aug 22; 6(1). PMID: 34417437    Free PMC article.
Review.
Expression of 5-methylcytosine regulators is highly associated with the clinical phenotypes of prostate cancer and DNMTs expression predicts biochemical recurrence.
Lin Wang, Guoping Ren, Biaoyang Lin.
Cancer Med, 2021 Jul 07; 10(16). PMID: 34227253    Free PMC article.
Tumor PD-L1 expression is associated with outcomes in stage III non-small cell lung cancer (NSCLC) patients treated with consolidation durvalumab.
Khalid Jazieh, Mohamed Gad, +2 authors, Nathan A Pennell.
Transl Lung Cancer Res, 2021 Aug 26; 10(7). PMID: 34430348    Free PMC article.
Differential Dermatologic Adverse Events Associated With Checkpoint Inhibitor Monotherapy and Combination Therapy: A Meta-Analysis of Randomized Control Trials.
Yang Ge, Huiyun Zhang, Nathaniel Weygant, Jiannan Yao.
Front Pharmacol, 2021 Aug 28; 12. PMID: 34447305    Free PMC article.
CAR T-Cell Therapy in Hematological Malignancies.
Theresa Haslauer, Richard Greil, Nadja Zaborsky, Roland Geisberger.
Int J Mol Sci, 2021 Aug 28; 22(16). PMID: 34445701    Free PMC article.
Review.
A peptidic inhibitor for PD-1 palmitoylation targets its expression and functions.
Han Yao, Chushu Li, +9 authors, Jie Xu.
RSC Chem Biol, 2021 Aug 31; 2(1). PMID: 34458782    Free PMC article.
The predictive and prognostic effects of PD-L1 expression on TKI treatment and survival of EGFR-mutant NSCLC: A meta-analysis.
Bo Lan, Yongfang Wang, +2 authors, Pingli Wang.
Medicine (Baltimore), 2021 Aug 28; 100(34). PMID: 34449486    Free PMC article.
Comprehensive analysis of BTN3A1 in cancers: mining of omics data and validation in patient samples and cellular models.
Fan Liang, Chen Zhang, +4 authors, Gui-Zhen Wang.
FEBS Open Bio, 2021 Jul 23; 11(9). PMID: 34293829    Free PMC article.
A ferroptosis-associated gene signature for the prediction of prognosis and therapeutic response in luminal-type breast carcinoma.
Yang Peng, Haochen Yu, +8 authors, Shengchun Liu.
Sci Rep, 2021 Sep 04; 11(1). PMID: 34475496    Free PMC article.
Characterization and Management of Adverse Reactions in Patients with Advanced Endometrial Carcinoma Treated with Lenvatinib Plus Pembrolizumab.
Vicky Makker, Matthew H Taylor, +6 authors, David M O'Malley.
Oncologist, 2021 Jul 01; 26(9). PMID: 34190370    Free PMC article.
Step-by-Step Immune Activation for Suicide Gene Therapy Reinforcement.
Irina Alekseenko, Alexey Kuzmich, +3 authors, Eugene Sverdlov.
Int J Mol Sci, 2021 Sep 11; 22(17). PMID: 34502287    Free PMC article.
Review.
Ovarian Cancer in the Era of Immune Checkpoint Inhibitors: State of the Art and Future Perspectives.
Brigida Anna Maiorano, Mauro Francesco Pio Maiorano, Domenica Lorusso, Evaristo Maiello.
Cancers (Basel), 2021 Sep 11; 13(17). PMID: 34503248    Free PMC article.
Review.
Effective tools for RNA-derived therapeutics: siRNA interference or miRNA mimicry.
Peipei Wang, Yue Zhou, Arthur M Richards.
Theranostics, 2021 Sep 16; 11(18). PMID: 34522211    Free PMC article.
Review.
Dermatologic infections in cancer patients treated with checkpoint inhibitors.
Mytrang H Do, Dulce M Barrios, +6 authors, Mario E Lacouture.
J Am Acad Dermatol, 2021 Mar 22; 85(6). PMID: 33744355    Free PMC article.
Upregulation of Cytotoxic T-Lymphocyte-Associated Protein 4 and Forkhead Box P3 Transcripts in Peripheral Blood of Patients with Bladder Cancer.
Ali Ariafar, Mojtaba Habibagahi, +5 authors, Mahboobeh Razmkhah.
Iran J Med Sci, 2021 Sep 21; 46(5). PMID: 34539008    Free PMC article.
Faecal microbiota transplantation enhances efficacy of immune checkpoint inhibitors therapy against cancer.
Yong-Bo Kang, Yue Cai.
World J Gastroenterol, 2021 Sep 21; 27(32). PMID: 34539138    Free PMC article.
Review.
Endocrine-related adverse events in a large series of cancer patients treated with anti-PD1 therapy.
Rossella Rubino, Andrea Marini, +10 authors, Alessandro Peri.
Endocrine, 2021 May 27; 74(1). PMID: 34036513    Free PMC article.
Inhibiting the Unconventionals: Importance of Immune Checkpoint Receptors in γδ T, MAIT, and NKT Cells.
Elisa Catafal-Tardos, Maria Virginia Baglioni, Vasileios Bekiaris.
Cancers (Basel), 2021 Sep 29; 13(18). PMID: 34572874    Free PMC article.
Review.
Estrogen Receptor Beta (ERβ) Maintains Mitochondrial Network Regulating Invasiveness in an Obesity-Related Inflammation Condition in Breast Cancer.
Toni Martinez-Bernabe, Jorge Sastre-Serra, +3 authors, Pilar Roca.
Antioxidants (Basel), 2021 Sep 29; 10(9). PMID: 34573003    Free PMC article.
A Human Pan-Cancer System Analysis of Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3).
Siming Gong, Yingjuan Duan, +3 authors, Sonja Kallendrusch.
Int J Mol Sci, 2021 Sep 29; 22(18). PMID: 34576068    Free PMC article.
Retinoids Delivery Systems in Cancer: Liposomal Fenretinide for Neuroectodermal-Derived Tumors.
Veronica Bensa, Enzo Calarco, +5 authors, Fabio Pastorino.
Pharmaceuticals (Basel), 2021 Sep 29; 14(9). PMID: 34577553    Free PMC article.
Review.
Diagnosis and Management of Immune Checkpoint Inhibitor Colitis.
Jana G Hashash, Fadi F Francis, Francis A Farraye.
Gastroenterol Hepatol (N Y), 2021 Oct 05; 17(8). PMID: 34602898    Free PMC article.
Oncolytic virus therapy in cancer: A current review.
Jonathan Santos Apolonio, Vinícius Lima de Souza Gonçalves, +6 authors, Fabrício Freire de Melo.
World J Virol, 2021 Oct 12; 10(5). PMID: 34631474    Free PMC article.
Review.
Combined inhibition of CXCL12 and PD-1 in MSS colorectal and pancreatic cancer: modulation of the microenvironment and clinical effects.
Meggy Suarez-Carmona, Anja Williams, +11 authors, Niels Halama.
J Immunother Cancer, 2021 Oct 06; 9(10). PMID: 34607895    Free PMC article.
Immunomodulating Therapies in Breast Cancer-From Prognosis to Clinical Practice.
Marcus Schmidt, Anne-Sophie Heimes.
Cancers (Basel), 2021 Oct 14; 13(19). PMID: 34638367    Free PMC article.
Review.
Acute kidney injury from immune checkpoint inhibitor use.
Lexis Gordon, Pouneh Dokouhaki, Kimberly Hagel, Bhanu Prasad.
BMJ Case Rep, 2019 Oct 28; 12(10). PMID: 31653633    Free PMC article.
Immunosuppressive Roles of Galectin-1 in the Tumor Microenvironment.
Yanyu Huang, Hsiao-Chi Wang, +2 authors, Tsung-Chieh Shih.
Biomolecules, 2021 Oct 24; 11(10). PMID: 34680031    Free PMC article.
Review.
Hodgkin Lymphoma: A Special Microenvironment.
Giuseppina Opinto, Claudio Agostinelli, +3 authors, Giuseppe Ingravallo.
J Clin Med, 2021 Oct 24; 10(20). PMID: 34682791    Free PMC article.
Review.
Real-World Incidence of Immune-Related Adverse Events Associated with Nivolumab Plus Ipilimumab in Patients with Advanced Renal Cell Carcinoma: A Retrospective Observational Study.
Satoshi Washino, Hideki Takeshita, +6 authors, Satoru Kawakami.
J Clin Med, 2021 Oct 24; 10(20). PMID: 34682890    Free PMC article.
The Frequency of DNA Mismatch Repair Deficiency Is Very Low in Surgically Resected Lung Carcinoma.
Naoki Yanagawa, Noriyuki Yamada, +8 authors, Tamotsu Sugai.
Front Oncol, 2021 Oct 26; 11. PMID: 34692533    Free PMC article.
Dissecting the single-cell transcriptome network in patients with esophageal squamous cell carcinoma receiving operative paclitaxel plus platinum chemotherapy.
Zhencong Chen, Yiwei Huang, +11 authors, Lijie Tan.
Oncogenesis, 2021 Oct 27; 10(10). PMID: 34697289    Free PMC article.
Structural analysis and binding sites of inhibitors targeting the CD47/SIRPα interaction in anticancer therapy.
Bo Huang, Zhaoshi Bai, +5 authors, Lingman Ma.
Comput Struct Biotechnol J, 2021 Oct 30; 19. PMID: 34712395    Free PMC article.
Review.
The prevalence of DNA microsatellite instability in anaplastic thyroid carcinoma - systematic review and discussion of current therapeutic options.
Maria Linda Rocha, Kurt Werner Schmid, Piotr Czapiewski.
Contemp Oncol (Pozn), 2021 Nov 04; 25(3). PMID: 34729042    Free PMC article.
Review.
Microbiome Crosstalk in Immunotherapy and Antiangiogenesis Therapy.
Xueting Wan, Mengyao Song, +3 authors, Yin Lu.
Front Immunol, 2021 Nov 09; 12. PMID: 34745119    Free PMC article.
Review.
Metabolism in tumor microenvironment: Implications for cancer immunotherapy.
Rongchen Shi, Yi-Quan Tang, Hongming Miao.
MedComm (2020), 2020 Jun 03; 1(1). PMID: 34766109    Free PMC article.
Review.
Immunosuppression in Glioblastoma: Current Understanding and Therapeutic Implications.
Benjamin T Himes, Philipp A Geiger, +3 authors, Ian F Parney.
Front Oncol, 2021 Nov 16; 11. PMID: 34778089    Free PMC article.
Review.
Prognosis and Immunotherapy Significances of a Cancer-Associated Fibroblasts-Related Gene Signature in Gliomas.
Zhimin Chen, Shenghua Zhuo, +5 authors, Huiming Xu.
Front Cell Dev Biol, 2021 Nov 16; 9. PMID: 34778248    Free PMC article.
Spherical Nucleic Acid Vaccine Structure Markedly Influences Adaptive Immune Responses of Clinically Utilized Prostate Cancer Targets.
Michelle H Teplensky, Jasper W Dittmar, +4 authors, Chad A Mirkin.
Adv Healthc Mater, 2021 Sep 09; 10(22). PMID: 34494382    Free PMC article.
Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma.
Darci Phillips, Magdalena Matusiak, +15 authors, Garry P Nolan.
Nat Commun, 2021 Nov 20; 12(1). PMID: 34795254    Free PMC article.
Risk Factors, Incidence, and Prognosis of Thromboembolism in Cancer Patients Treated With Immune Checkpoint Inhibitors.
Xue-Lin Zou, Wei-Yong Chen, +3 authors, Xiao-Bo Li.
Front Pharmacol, 2021 Nov 26; 12. PMID: 34819857    Free PMC article.
Review.
Cardiotoxicity of Antineoplastic Therapies and Applications of Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Mo-Fan Huang, Lon Kai Pang, +2 authors, Dung-Fang Lee.
Cells, 2021 Nov 28; 10(11). PMID: 34831045    Free PMC article.
Review.
Nanomedicine for Immunotherapy Targeting Hematological Malignancies: Current Approaches and Perspective.
Alessandro Allegra, Mario Di Gioacchino, +2 authors, Sebastiano Gangemi.
Nanomaterials (Basel), 2021 Nov 28; 11(11). PMID: 34835555    Free PMC article.
Review.
Targeted Anti-Tumor Immunotherapy Using Tumor Infiltrating Cells.
Yifan Xie, Feng Xie, +7 authors, Fangfang Zhou.
Adv Sci (Weinh), 2021 Oct 19; 8(22). PMID: 34658167    Free PMC article.
Review.
Early prediction of clinical response to checkpoint inhibitor therapy in human solid tumors through mathematical modeling.
Joseph D Butner, Geoffrey V Martin, +18 authors, Vittorio Cristini.
Elife, 2021 Nov 10; 10. PMID: 34749885    Free PMC article.
Whole-body PET Imaging of T-cell Response to Glioblastoma.
Tomomi W Nobashi, Aaron T Mayer, +4 authors, Sanjiv S Gambhir.
Clin Cancer Res, 2021 Sep 23; 27(23). PMID: 34548318    Free PMC article.
Solid Tumor Microenvironment Can Harbor and Support Functional Properties of Memory T Cells.
Peter M Sullivan, Steven James Reed, Vandana Kalia, Surojit Sarkar.
Front Immunol, 2021 Dec 07; 12. PMID: 34867942    Free PMC article.
Identification of the Upregulation of MRPL13 as a Novel Prognostic Marker Associated with Overall Survival Time and Immunotherapy Response in Breast Cancer.
Hongshan Ye, Ning Zhang.
Comput Math Methods Med, 2021 Dec 07; 2021. PMID: 34868337    Free PMC article.
Personalized immunotherapy in cancer precision medicine.
Kazuma Kiyotani, Yujiro Toyoshima, Yusuke Nakamura.
Cancer Biol Med, 2021 Aug 10;. PMID: 34369137    Free PMC article.
Review.
Expression signature, prognosis value and immune characteristics of cathepsin F in non-small cell lung cancer identified by bioinformatics assessment.
Liyuan Song, Xianhui Wang, +10 authors, Fuyun Ji.
BMC Pulm Med, 2021 Dec 21; 21(1). PMID: 34923982    Free PMC article.
Signal pathways of melanoma and targeted therapy.
Weinan Guo, Huina Wang, Chunying Li.
Signal Transduct Target Ther, 2021 Dec 21; 6(1). PMID: 34924562    Free PMC article.
Review.
Vaccination against Cancer or Infectious Agents during Checkpoint Inhibitor Therapy.
Tahseen H Nasti, Christiane S Eberhardt.
Vaccines (Basel), 2021 Dec 29; 9(12). PMID: 34960142    Free PMC article.
Review.
Adjunctive Probiotic Lactobacillus rhamnosus Probio-M9 Administration Enhances the Effect of Anti-PD-1 Antitumor Therapy via Restoring Antibiotic-Disrupted Gut Microbiota.
Guangqi Gao, Teng Ma, +5 authors, Zhihong Sun.
Front Immunol, 2022 Jan 01; 12. PMID: 34970262    Free PMC article.
Comprehensive Analysis to Identify MAGEA3 Expression Correlated With Immune Infiltrates and Lymph Node Metastasis in Gastric Cancer.
Jinji Jin, Jianxin Tu, +5 authors, Guanbao Zhu.
Front Oncol, 2022 Jan 01; 11. PMID: 34970496    Free PMC article.
Therapeutic advances in non-small cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy.
Yuan Cheng, Tao Zhang, Qing Xu.
MedComm (2020), 2022 Jan 04; 2(4). PMID: 34977873