. 2015 Apr; 348(6230):56-61.
doi: 10.1126/science.aaa8172.

The future of immune checkpoint therapy

Padmanee Sharma 1 James P Allison 2 
  • PMID: 25838373
  •     1611 citations


Immune checkpoint therapy, which targets regulatory pathways in T cells to enhance antitumor immune responses, has led to important clinical advances and provided a new weapon against cancer. This therapy has elicited durable clinical responses and, in a fraction of patients, long-term remissions where patients exhibit no clinical signs of cancer for many years. The way forward for this class of novel agents lies in our ability to understand human immune responses in the tumor microenvironment. This will provide valuable information regarding the dynamic nature of the immune response and regulation of additional pathways that will need to be targeted through combination therapies to provide survival benefit for greater numbers of patients.

Imaging the Tumor Microenvironment.
Valerie S LeBleu.
Cancer J, 2015 Jun 08; 21(3). PMID: 26049696    Free PMC article.
Molecular Pathways: Activating T Cells after Cancer Cell Phagocytosis from Blockade of CD47 "Don't Eat Me" Signals.
Melissa N McCracken, Adriel C Cha, Irving L Weissman.
Clin Cancer Res, 2015 Jun 28; 21(16). PMID: 26116271    Free PMC article.
Engineering New Approaches to Cancer Vaccines.
Naveen K Mehta, Kelly D Moynihan, Darrell J Irvine.
Cancer Immunol Res, 2015 Jul 15; 3(8). PMID: 26156157    Free PMC article.
Understanding the function and dysfunction of the immune system in lung cancer: the role of immune checkpoints.
Niki Karachaliou, Maria Gonzalez Cao, +4 authors, Rafael Rosell.
Cancer Biol Med, 2015 Jul 16; 12(2). PMID: 26175923    Free PMC article.
Fusobacterium nucleatum and T Cells in Colorectal Carcinoma.
Kosuke Mima, Yasutaka Sukawa, +22 authors, Shuji Ogino.
JAMA Oncol, 2015 Jul 17; 1(5). PMID: 26181352    Free PMC article.
Highly Cited.
Research and development of therapeutic mAbs: An analysis based on pipeline projects.
Xiaomei Geng, Xiangjun Kong, +5 authors, Yuanjia Hu.
Hum Vaccin Immunother, 2015 Jul 28; 11(12). PMID: 26211701    Free PMC article.
PD-1(hi)TIM-3(+) T cells associate with and predict leukemia relapse in AML patients post allogeneic stem cell transplantation.
Y Kong, J Zhang, +6 authors, H Zheng.
Blood Cancer J, 2015 Aug 01; 5. PMID: 26230954    Free PMC article.
Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target.
Hmc Shantha Kumara, Daniel Kirchoff, +8 authors, Richard L Whelan.
Oncoscience, 2015 Aug 06; 2(6). PMID: 26244168    Free PMC article.
New and emerging factors in tumorigenesis: an overview.
Suwon Kim.
Cancer Manag Res, 2015 Aug 08; 7. PMID: 26251629    Free PMC article.
Tumor neoantigens: building a framework for personalized cancer immunotherapy.
Matthew M Gubin, Maxim N Artyomov, Elaine R Mardis, Robert D Schreiber.
J Clin Invest, 2015 Aug 11; 125(9). PMID: 26258412    Free PMC article.
Highly Cited. Review.
T cell metabolic reprogramming and plasticity.
Maria Slack, Tingting Wang, Ruoning Wang.
Mol Immunol, 2015 Aug 19; 68(2 Pt C). PMID: 26277274    Free PMC article.
Corticosteroids and immune checkpoint blockade.
Le Min, F Stephen Hodi, Ursula B Kaiser.
Aging (Albany NY), 2015 Aug 25; 7(8). PMID: 26298620    Free PMC article.
Tumor infiltrating lymphocyte therapy for ovarian cancer and renal cell carcinoma.
Rikke Andersen, Marco Donia, +3 authors, Inge Marie Svane.
Hum Vaccin Immunother, 2015 Aug 27; 11(12). PMID: 26308285    Free PMC article.
The Promise of Preventive Cancer Vaccines.
Pier-Luigi Lollini, Federica Cavallo, Patrizia Nanni, Elena Quaglino.
Vaccines (Basel), 2015 Sep 08; 3(2). PMID: 26343198    Free PMC article.
Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity.
Santiago Zelenay, Annemarthe G van der Veen, +9 authors, Caetano Reis e Sousa.
Cell, 2015 Sep 08; 162(6). PMID: 26343581    Free PMC article.
Highly Cited.
Cancer immunotherapy innovator James Allison receives the 2015 Lasker~DeBakey Clinical Medical Research Award.
Jillian H Hurst.
J Clin Invest, 2015 Sep 09; 125(10). PMID: 26345422    Free PMC article.
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.
Eliezer M Van Allen, Diana Miao, +19 authors, Levi A Garraway.
Science, 2015 Sep 12; 350(6257). PMID: 26359337    Free PMC article.
Highly Cited.
Multiple structural and epigenetic defects in the human leukocyte antigen class I antigen presentation pathway in a recurrent metastatic melanoma following immunotherapy.
Chien-Chung Chang, Giuseppe Pirozzi, +6 authors, Soldano Ferrone.
J Biol Chem, 2015 Sep 19; 290(44). PMID: 26381407    Free PMC article.
Targeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor Immunity.
Katherine A Waugh, Sonia M Leach, Jill E Slansky.
Vaccines (Basel), 2015 Sep 24; 3(3). PMID: 26393659    Free PMC article.
T-cell receptor profiling in cancer.
Ilan Kirsch, Marissa Vignali, Harlan Robins.
Mol Oncol, 2015 Sep 26; 9(10). PMID: 26404496    Free PMC article.
MicroRNA MIR21 and T Cells in Colorectal Cancer.
Kosuke Mima, Reiko Nishihara, +20 authors, Shuji Ogino.
Cancer Immunol Res, 2015 Oct 01; 4(1). PMID: 26419959    Free PMC article.
Targets, Toxins, and T Cells--a Review of New Monoclonal Antibodies in the Treatment of Peripheral T Cell Lymphomas.
Jonathan Hebb, Holbrook Kohrt.
Curr Hematol Malig Rep, 2015 Oct 05; 10(4). PMID: 26433890
Gene therapy returns to centre stage.
Luigi Naldini.
Nature, 2015 Oct 16; 526(7573). PMID: 26469046
Highly Cited. Review.
The oncolytic peptide LTX-315 induces cell death and DAMP release by mitochondria distortion in human melanoma cells.
Liv-Marie Eike, Nannan Yang, Øystein Rekdal, Baldur Sveinbjørnsson.
Oncotarget, 2015 Oct 17; 6(33). PMID: 26472184    Free PMC article.
Improving immunological tumor microenvironment using electro-hyperthermia followed by dendritic cell immunotherapy.
Yuk-Wah Tsang, Cheng-Chung Huang, +7 authors, Kwan-Hwa Chi.
BMC Cancer, 2015 Oct 17; 15. PMID: 26472466    Free PMC article.
Mechanisms of adaptation and progression in idiosyncratic drug induced liver injury, clinical implications.
Lily Dara, Zhang-Xu Liu, Neil Kaplowitz.
Liver Int, 2015 Oct 21; 36(2). PMID: 26484420    Free PMC article.
Exploiting the Immunomodulatory Properties of Chemotherapeutic Drugs to Improve the Success of Cancer Immunotherapy.
Kelly Kersten, Camilla Salvagno, Karin E de Visser.
Front Immunol, 2015 Oct 27; 6. PMID: 26500653    Free PMC article.
Great science inspires us to tackle the issue of data reproducibility.
David G Drubin.
Mol Biol Cell, 2015 Oct 31; 26(21). PMID: 26515968    Free PMC article.
Immunoproteasomes edit tumors, which then escapes immune recognition.
Sebastian Joyce.
Eur J Immunol, 2015 Nov 04; 45(12). PMID: 26527367    Free PMC article.
Precision medicine for cancer with next-generation functional diagnostics.
Adam A Friedman, Anthony Letai, David E Fisher, Keith T Flaherty.
Nat Rev Cancer, 2015 Nov 06; 15(12). PMID: 26536825    Free PMC article.
Highly Cited. Review.
Immune-checkpoint blockade: the springboard for immuno-combination therapy.
A M Ibrahim, Y Wang, N R Lemoine.
Gene Ther, 2015 Nov 06; 22(11). PMID: 26537748
T-cell receptor gene therapy--ready to go viral?
Terhi Karpanen, Johanna Olweus.
Mol Oncol, 2015 Nov 10; 9(10). PMID: 26548533    Free PMC article.
Functional Specialization of Skin Dendritic Cell Subsets in Regulating T Cell Responses.
Björn E Clausen, Patrizia Stoitzner.
Front Immunol, 2015 Nov 12; 6. PMID: 26557117    Free PMC article.
The combination of dendritic cells-cytotoxic T lymphocytes/cytokine-induced killer (DC-CTL/CIK) therapy exerts immune and clinical responses in patients with malignant tumors.
Ying Wang, Zenghui Xu, +5 authors, Qijun Qian.
Exp Hematol Oncol, 2015 Nov 13; 4. PMID: 26561538    Free PMC article.
A Pt(IV) Pro-drug Preferentially Targets Indoleamine-2,3-dioxygenase, Providing Enhanced Ovarian Cancer Immuno-Chemotherapy.
Samuel G Awuah, Yao-Rong Zheng, +2 authors, Stephen J Lippard.
J Am Chem Soc, 2015 Nov 13; 137(47). PMID: 26561720    Free PMC article.
Strategies and Advancements in Harnessing the Immune System for Gastric Cancer Immunotherapy.
Vinod Vijay Subhash, Mei Shi Yeo, Woei Loon Tan, Wei Peng Yong.
J Immunol Res, 2015 Nov 19; 2015. PMID: 26579545    Free PMC article.
[Clinical Research Progress of Anti PD-1/PD-L1 Monoclonal Antibody in the Treatment of Lung Cancer].
Zhiyu Huang, Hui Li, Yun Fan.
Zhongguo Fei Ai Za Zhi, 2015 Nov 20; 18(11). PMID: 26582228    Free PMC article.
Engineering opportunities in cancer immunotherapy.
Laura Jeanbart, Melody A Swartz.
Proc Natl Acad Sci U S A, 2015 Nov 26; 112(47). PMID: 26598681    Free PMC article.
Combination cancer immunotherapies tailored to the tumour microenvironment.
Mark J Smyth, Shin Foong Ngiow, Antoni Ribas, Michele W L Teng.
Nat Rev Clin Oncol, 2015 Nov 26; 13(3). PMID: 26598942
Highly Cited. Review.
Gastric cancer: The times they are a-changin'.
Maria Antonietta Satolli, Lucio Buffoni, Rosella Spadi, Ilaria Roato.
World J Gastrointest Oncol, 2015 Nov 26; 7(11). PMID: 26600930    Free PMC article.
Raising the bar: optimizing combinations of targeted therapy and immunotherapy.
Alexandre Reuben, Jacob Austin-Breneman, Jennifer A Wargo, Zachary A Cooper.
Ann Transl Med, 2015 Nov 26; 3(18). PMID: 26605318    Free PMC article.
Precision Medicine for Molecularly Targeted Agents and Immunotherapies in Early-Phase Clinical Trials.
Juanita Lopez, Sam Harris, Desam Roda, Timothy A Yap.
Transl Oncogenomics, 2015 Nov 27; 7(Suppl 1). PMID: 26609214    Free PMC article.
Oncolytic Adenovirus: Strategies and Insights for Vector Design and Immuno-Oncolytic Applications.
Hanni Uusi-Kerttula, Sarah Hulin-Curtis, James Davies, Alan L Parker.
Viruses, 2015 Nov 28; 7(11). PMID: 26610547    Free PMC article.
Image-Guided Biopsy in the Era of Personalized Cancer Care: Proceedings from the Society of Interventional Radiology Research Consensus Panel.
Alda L Tam, Howard J Lim, +11 authors, Kamran Ahrar.
J Vasc Interv Radiol, 2015 Dec 03; 27(1). PMID: 26626860    Free PMC article.
Analysis of Major Histocompatibility Complex (MHC) Immunopeptidomes Using Mass Spectrometry.
Etienne Caron, Daniel J Kowalewski, +3 authors, Ruedi Aebersold.
Mol Cell Proteomics, 2015 Dec 03; 14(12). PMID: 26628741    Free PMC article.
Highly Cited. Review.
In situ vaccination: Cancer immunotherapy both personalized and off-the-shelf.
Linda Hammerich, Adam Binder, Joshua D Brody.
Mol Oncol, 2015 Dec 04; 9(10). PMID: 26632446    Free PMC article.
Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death.
Abhishek D Garg, Lorenzo Galluzzi, +49 authors, Patrizia Agostinis.
Front Immunol, 2015 Dec 05; 6. PMID: 26635802    Free PMC article.
Highly Cited.
Antibody-like Biorecognition Sites for Proteins from Surface Imprinting on Nanoparticles.
Snehasis Bhakta, Mohammad Saiful Islam Seraji, Steven L Suib, James F Rusling.
ACS Appl Mater Interfaces, 2015 Dec 05; 7(51). PMID: 26636440    Free PMC article.
Clinical relevance of host immunity in breast cancer: from TILs to the clinic.
Peter Savas, Roberto Salgado, +4 authors, Sherene Loi.
Nat Rev Clin Oncol, 2015 Dec 17; 13(4). PMID: 26667975
Highly Cited. Review.
Exercise in Regulation of Inflammation-Immune Axis Function in Cancer Initiation and Progression.
Graeme J Koelwyn, Erik Wennerberg, Sandra Demaria, Lee W Jones.
Oncology (Williston Park), 2015 Dec 18; 29(12). PMID: 26676894    Free PMC article.
Lessons from other diseases: granulomatous inflammation in leishmaniasis.
Paul M Kaye, Lynette Beattie.
Semin Immunopathol, 2015 Dec 19; 38(2). PMID: 26678994    Free PMC article.
New Strategies in Bladder Cancer: A Second Coming for Immunotherapy.
Ali Ghasemzadeh, Trinity J Bivalacqua, Noah M Hahn, Charles G Drake.
Clin Cancer Res, 2015 Dec 20; 22(4). PMID: 26683632    Free PMC article.
Delivery of cancer therapeutics to extracellular and intracellular targets: Determinants, barriers, challenges and opportunities.
Jessie L-S Au, Bertrand Z Yeung, +2 authors, M Guillaume Wientjes.
Adv Drug Deliv Rev, 2015 Dec 22; 97. PMID: 26686425    Free PMC article.
Immunosuppressive cells in tumor immune escape and metastasis.
Yang Liu, Xuetao Cao.
J Mol Med (Berl), 2015 Dec 23; 94(5). PMID: 26689709
Predictors of clinical response to immunotherapy with or without radiotherapy.
Susan M Hiniker, Holden T Maecker, Susan J Knox.
J Radiat Oncol, 2015 Dec 29; 4. PMID: 26709361    Free PMC article.
Immune Checkpoint Blockade in Hepatocellular Carcinoma.
M Kudo.
Liver Cancer, 2016 Jan 07; 4(4). PMID: 26732472    Free PMC article.
Overcoming Barriers in Oncolytic Virotherapy with HDAC Inhibitors and Immune Checkpoint Blockade.
Antonio Marchini, Eleanor M Scott, Jean Rommelaere.
Viruses, 2016 Jan 12; 8(1). PMID: 26751469    Free PMC article.
Tumor-Induced Local and Systemic Impact on Blood Vessel Function.
J Cedervall, A Dimberg, A-K Olsson.
Mediators Inflamm, 2016 Jan 16; 2015. PMID: 26770016    Free PMC article.
Ligand-targeted theranostic nanomedicines against cancer.
Virginia J Yao, Sara D'Angelo, +10 authors, Renata Pasqualini.
J Control Release, 2016 Jan 17; 240. PMID: 26772878    Free PMC article.
Potential biomarker for checkpoint blockade immunotherapy and treatment strategy.
Zhong-Yi Dong, Si-Pei Wu, +2 authors, Yi-Long Wu.
Tumour Biol, 2016 Jan 19; 37(4). PMID: 26779629
Secreted Thrombospondin-1 Regulates Macrophage Interleukin-1β Production and Activation through CD47.
Erica V Stein, Thomas W Miller, +2 authors, David D Roberts.
Sci Rep, 2016 Jan 28; 6. PMID: 26813769    Free PMC article.
The role of microbiota in cancer therapy.
Ernesto Perez-Chanona, Giorgio Trinchieri.
Curr Opin Immunol, 2016 Jan 29; 39. PMID: 26820225    Free PMC article.
Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?
Paul A Bunn, John D Minna, +51 authors, Fred R Hirsch.
J Thorac Oncol, 2016 Feb 02; 11(4). PMID: 26829312    Free PMC article.
Highly Cited. Review.
Immunotherapy of cancer: from monoclonal to oligoclonal cocktails of anti-cancer antibodies: IUPHAR Review 18.
Silvia Carvalho, Francesca Levi-Schaffer, Michael Sela, Yosef Yarden.
Br J Pharmacol, 2016 Feb 03; 173(9). PMID: 26833433    Free PMC article.
Enhancing the safety of antibody-based immunomodulatory cancer therapy without compromising therapeutic benefit: Can we have our cake and eat it too?
Joseph M Ryan, Jeffrey S Wasser, Adam J Adler, Anthony T Vella.
Expert Opin Biol Ther, 2016 Feb 09; 16(5). PMID: 26855028    Free PMC article.
Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers.
D P Granados, A Rodenbrock, +12 authors, C Perreault.
Leukemia, 2016 Feb 10; 30(6). PMID: 26857467
The Lymphatic System in Disease Processes and Cancer Progression.
Timothy P Padera, Eelco F J Meijer, Lance L Munn.
Annu Rev Biomed Eng, 2016 Feb 13; 18. PMID: 26863922    Free PMC article.
Immunocytokines and bispecific antibodies: two complementary strategies for the selective activation of immune cells at the tumor site.
Jonathan D Kiefer, Dario Neri.
Immunol Rev, 2016 Feb 13; 270(1). PMID: 26864112    Free PMC article.
Combined Immune Therapy for the Treatment of Visceral Leishmaniasis.
Rebecca J Faleiro, Rajiv Kumar, +15 authors, Christian R Engwerda.
PLoS Negl Trop Dis, 2016 Feb 13; 10(2). PMID: 26872334    Free PMC article.
Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy.
Christina Pfirschke, Camilla Engblom, +18 authors, Mikael J Pittet.
Immunity, 2016 Feb 14; 44(2). PMID: 26872698    Free PMC article.
Highly Cited.
Immunogenic versus tolerogenic phagocytosis during anticancer therapy: mechanisms and clinical translation.
A D Garg, E Romano, N Rufo, P Agostinis.
Cell Death Differ, 2016 Feb 20; 23(6). PMID: 26891691    Free PMC article.
Transformation of the tumour microenvironment by a CD40 agonist antibody correlates with improved responses to PD-L1 blockade in a mouse orthotopic pancreatic tumour model.
Nadia M Luheshi, Jane Coates-Ulrichsen, +8 authors, Robert W Wilkinson.
Oncotarget, 2016 Feb 27; 7(14). PMID: 26918344    Free PMC article.
Hepatocellular carcinoma cell sensitivity to Vγ9Vδ2 T lymphocyte-mediated killing is increased by zoledronate.
Shiori Sugai, Toshiaki Yoshikawa, +8 authors, Tetsuya Nakatsura.
Int J Oncol, 2016 Mar 05; 48(5). PMID: 26936487    Free PMC article.
Oncolytic immunotherapy: The new clinical outbreak.
Jean-François Fonteneau, Carole Achard, +2 authors, Philippe Erbs.
Oncoimmunology, 2016 Mar 05; 5(1). PMID: 26942085    Free PMC article.
DNA-inorganic hybrid nanovaccine for cancer immunotherapy.
Guizhi Zhu, Yijing Liu, +11 authors, Xiaoyuan Chen.
Nanoscale, 2016 Mar 08; 8(12). PMID: 26947116    Free PMC article.
Ontogeny of Tumor-associated Macrophages and Its Implication in Cancer Regulation.
Ruth A Franklin, Ming O Li.
Trends Cancer, 2016 Mar 08; 2(1). PMID: 26949745    Free PMC article.
The adhesion molecule PECAM-1 enhances the TGF-β-mediated inhibition of T cell function.
Debra K Newman, Guoping Fu, +4 authors, Matthew J Riese.
Sci Signal, 2016 Mar 10; 9(418). PMID: 26956486    Free PMC article.
Cellular and molecular biology of small cell lung cancer: an overview.
Niki Karachaliou, Sara Pilotto, +3 authors, Rafael Rosell.
Transl Lung Cancer Res, 2016 Mar 10; 5(1). PMID: 26958489    Free PMC article.
Key players in pancreatic cancer-stroma interaction: Cancer-associated fibroblasts, endothelial and inflammatory cells.
Michael Friberg Bruun Nielsen, Michael Bau Mortensen, Sönke Detlefsen.
World J Gastroenterol, 2016 Mar 15; 22(9). PMID: 26973408    Free PMC article.
Highly Cited. Review.
A primer on tumour immunology and prostate cancer immunotherapy.
Runhan Ren, Madhuri Koti, +5 authors, D Robert Siemens.
Can Urol Assoc J, 2016 Mar 16; 10(1-2). PMID: 26977209    Free PMC article.
Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism.
Wei Yang, Yibing Bai, +19 authors, Chenqi Xu.
Nature, 2016 Mar 17; 531(7596). PMID: 26982734    Free PMC article.
Highly Cited.
High-sensitivity HLA class I peptidome analysis enables a precise definition of peptide motifs and the identification of peptides from cell lines and patients' sera.
Danilo Ritz, Andreas Gloger, +3 authors, Tim Fugmann.
Proteomics, 2016 Mar 19; 16(10). PMID: 26992070    Free PMC article.
Chimeric Antigen Receptor-Modified T Cells for Solid Tumors: Challenges and Prospects.
Yelei Guo, Yao Wang, Weidong Han.
J Immunol Res, 2016 Mar 22; 2016. PMID: 26998495    Free PMC article.
Emerging therapeutic targets in metastatic progression: A focus on breast cancer.
Zhuo Li, Yibin Kang.
Pharmacol Ther, 2016 Mar 24; 161. PMID: 27000769    Free PMC article.
Tremelimumab: research and clinical development.
Begoña Comin-Anduix, Helena Escuin-Ordinas, Francisco Javier Ibarrondo.
Onco Targets Ther, 2016 Apr 05; 9. PMID: 27042127    Free PMC article.
Thermal Ablative Therapies and Immune Checkpoint Modulation: Can Locoregional Approaches Effect a Systemic Response?
Amol Mehta, Rahmi Oklu, Rahul A Sheth.
Gastroenterol Res Pract, 2016 Apr 07; 2016. PMID: 27051417    Free PMC article.
Prognostic effect of different PD-L1 expression patterns in squamous cell carcinoma and adenocarcinoma of the cervix.
A Marijne Heeren, Simone Punt, +5 authors, Ekaterina S Jordanova.
Mod Pathol, 2016 Apr 09; 29(7). PMID: 27056074    Free PMC article.
Highly Cited.
Luciferase mRNA Transfection of Antigen Presenting Cells Permits Sensitive Nonradioactive Measurement of Cellular and Humoral Cytotoxicity.
Tana A Omokoko, Uli Luxemburger, +5 authors, Ugur Sahin.
J Immunol Res, 2016 Apr 09; 2016. PMID: 27057556    Free PMC article.
Progress in Adaptive Immunotherapy for Cancer in Companion Animals: Success on the Path to a Cure.
Katie L Anderson, Jaime F Modiano.
Vet Sci, 2016 Apr 12; 2(4). PMID: 27066495    Free PMC article.
SHP-1: the next checkpoint target for cancer immunotherapy?
H Angharad Watson, Sophie Wehenkel, James Matthews, Ann Ager.
Biochem Soc Trans, 2016 Apr 14; 44(2). PMID: 27068940    Free PMC article.
Sexual dimorphism in cancer.
Andrea Clocchiatti, Elisa Cora, Yosra Zhang, G Paolo Dotto.
Nat Rev Cancer, 2016 Apr 16; 16(5). PMID: 27079803
Highly Cited. Review.
Tumor-Infiltrating Lymphocytes in Triple Negative Breast Cancer: The Future of Immune Targeting.
Paula García-Teijido, María Luque Cabal, Ignacio Peláez Fernández, Yolanda Fernández Pérez.
Clin Med Insights Oncol, 2016 Apr 16; 10(Suppl 1). PMID: 27081325    Free PMC article.
Highly Cited. Review.
Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1).
Krzysztof M Zak, Przemyslaw Grudnik, +5 authors, Tad A Holak.
Oncotarget, 2016 Apr 16; 7(21). PMID: 27083005    Free PMC article.
Highly Cited.
Emerging Opportunities and Challenges in Cancer Immunotherapy.
Theresa L Whiteside, Sandra Demaria, +2 authors, Ignacio Melero.
Clin Cancer Res, 2016 Apr 17; 22(8). PMID: 27084738    Free PMC article.
Highly Cited. Review.
Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.
Hélène Salmon, Juliana Idoyaga, +19 authors, Miriam Merad.
Immunity, 2016 Apr 21; 44(4). PMID: 27096321    Free PMC article.
Highly Cited.
Tumor control with PD-1 inhibition in a patient with concurrent metastatic melanoma and renal cell carcinoma.
Melina E Marmarelis, Meredith R Davis, +4 authors, Patrick A Ott.
J Immunother Cancer, 2016 Apr 22; 4. PMID: 27099755    Free PMC article.
Isolation of Pancreatic Cancer Cells from a Patient-Derived Xenograft Model Allows for Practical Expansion and Preserved Heterogeneity in Culture.
Kien Pham, Daniel Delitto, +10 authors, Jose G Trevino.
Am J Pathol, 2016 Apr 23; 186(6). PMID: 27102771    Free PMC article.
Immune Checkpoint Therapy and the Search for Predictive Biomarkers.
Padmanee Sharma.
Cancer J, 2016 Apr 26; 22(2). PMID: 27111900    Free PMC article.
Immune Checkpoint Therapies in Prostate Cancer.
Sangeeta Goswami, Ana Aparicio, Sumit K Subudhi.
Cancer J, 2016 Apr 26; 22(2). PMID: 27111907    Free PMC article.
[Renaissance of immuno-oncology for urological tumors : Current status].
M-O Grimm, Y Winkler, I Fetter, H Oppel-Heuchel.
Urologe A, 2016 Apr 28; 55(5). PMID: 27119960
Low Frequency of Programmed Death Ligand 1 Expression in Pediatric Cancers.
Takahiro Aoki, Moeko Hino, +8 authors, Shinichiro Motohashi.
Pediatr Blood Cancer, 2016 May 03; 63(8). PMID: 27135656    Free PMC article.
Nivolumab, anti-programmed death-1 (PD-1) monoclonal antibody immunotherapy: Role in advanced cancers.
Arun Rajan, Chul Kim, +2 authors, James L Gulley.
Hum Vaccin Immunother, 2016 May 03; 12(9). PMID: 27135835    Free PMC article.
Growth and Metastasis of Intraocular Tumors in Aged Mice.
Zhiqiang Han, Joseph R Brown, Jerry Y Niederkorn.
Invest Ophthalmol Vis Sci, 2016 May 04; 57(6). PMID: 27138736    Free PMC article.
[Therapy monitoring and management of adverse events in PD-1/PD-L1 immune checkpoint inhibition].
H Oppel-Heuchel, M-O Grimm.
Urologe A, 2016 May 06; 55(5). PMID: 27146870
Regulation of Natural Killer Cell Function by STAT3.
Nicholas A Cacalano.
Front Immunol, 2016 May 06; 7. PMID: 27148255    Free PMC article.
Cancer immunotherapy: the beginning of the end of cancer?
Sofia Farkona, Eleftherios P Diamandis, Ivan M Blasutig.
BMC Med, 2016 May 07; 14. PMID: 27151159    Free PMC article.
Highly Cited. Review.
NLRC5/MHC class I transactivator is a target for immune evasion in cancer.
Sayuri Yoshihama, Jason Roszik, +7 authors, Koichi S Kobayashi.
Proc Natl Acad Sci U S A, 2016 May 11; 113(21). PMID: 27162338    Free PMC article.
Highly Cited.
Squamous Cell Cancers: A Unified Perspective on Biology and Genetics.
G Paolo Dotto, Anil K Rustgi.
Cancer Cell, 2016 May 12; 29(5). PMID: 27165741    Free PMC article.
Highly Cited. Review.
Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression.
Megan M Kaneda, Paola Cappello, +13 authors, Judith A Varner.
Cancer Discov, 2016 May 15; 6(8). PMID: 27179037    Free PMC article.
Highly Cited.
PD-1 marks dysfunctional regulatory T cells in malignant gliomas.
Daniel E Lowther, Brittany A Goods, +10 authors, David A Hafler.
JCI Insight, 2016 May 18; 1(5). PMID: 27182555    Free PMC article.
Highly Cited.
Microfluidic models for adoptive cell-mediated cancer immunotherapies.
Giulia Adriani, Andrea Pavesi, +3 authors, Roger D Kamm.
Drug Discov Today, 2016 May 18; 21(9). PMID: 27185084    Free PMC article.
Phase I study to evaluate toxicity and feasibility of intratumoral injection of α-gal glycolipids in patients with advanced melanoma.
Mark R Albertini, Erik A Ranheim, +12 authors, Uri Galili.
Cancer Immunol Immunother, 2016 May 22; 65(8). PMID: 27207605    Free PMC article.
Advances in PET Detection of the Antitumor T Cell Response.
M N McCracken, R Tavaré, O N Witte, A M Wu.
Adv Immunol, 2016 May 29; 131. PMID: 27235684    Free PMC article.
Monitoring immune responses in the tumor microenvironment.
Jennifer A Wargo, Sangeetha M Reddy, Alexandre Reuben, Padmanee Sharma.
Curr Opin Immunol, 2016 May 31; 41. PMID: 27240055    Free PMC article.
FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review).
Masaru Katoh.
Int J Mol Med, 2016 Jun 02; 38(1). PMID: 27245147    Free PMC article.
Highly Cited. Review.
A second chance for telomerase reverse transcriptase in anticancer immunotherapy.
Maurizio Zanetti.
Nat Rev Clin Oncol, 2016 Nov 03; 14(2). PMID: 27245281
CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma.
Colin W Steele, Saadia A Karim, +23 authors, Jennifer P Morton.
Cancer Cell, 2016 Jun 07; 29(6). PMID: 27265504    Free PMC article.
Highly Cited.
What does the future hold for immunotherapy in cancer?
Jarushka Naidoo, Bob T Li, Katja Schindler, David B Page.
Ann Transl Med, 2016 Jun 09; 4(9). PMID: 27275490    Free PMC article.
CD40 Stimulation Obviates Innate Sensors and Drives T Cell Immunity in Cancer.
Katelyn T Byrne, Robert H Vonderheide.
Cell Rep, 2016 Jun 14; 15(12). PMID: 27292635    Free PMC article.
Highly Cited.
Potential of immunomodulatory agents as adjunct host-directed therapies for multidrug-resistant tuberculosis.
Alimuddin Zumla, Martin Rao, Ernest Dodoo, Markus Maeurer.
BMC Med, 2016 Jun 16; 14. PMID: 27301245    Free PMC article.
Some vexations that challenge viral immunology.
Barry T Rouse, Scott N Mueller.
F1000Res, 2016 Jun 16; 5. PMID: 27303640    Free PMC article.
Genetic screens to study the immune system in cancer.
Kai W Wucherpfennig, Adam Nr Cartwright.
Curr Opin Immunol, 2016 Jun 17; 41. PMID: 27309352    Free PMC article.
Effector, Memory, and Dysfunctional CD8(+) T Cell Fates in the Antitumor Immune Response.
John Reiser, Arnob Banerjee.
J Immunol Res, 2016 Jun 18; 2016. PMID: 27314056    Free PMC article.
The role of myeloid cells in cancer therapies.
Camilla Engblom, Christina Pfirschke, Mikael J Pittet.
Nat Rev Cancer, 2016 Jun 25; 16(7). PMID: 27339708
Highly Cited. Review.
Neoantigen landscape dynamics during human melanoma-T cell interactions.
Els M E Verdegaal, Noel F C C de Miranda, +11 authors, Sjoerd H van der Burg.
Nature, 2016 Jun 29; 536(7614). PMID: 27350335
Highly Cited.
CTLA4 as Immunological Checkpoint in the Development of Multiple Sclerosis.
Lisa Ann Gerdes, Kathrin Held, +9 authors, Reinhard Hohlfeld.
Ann Neurol, 2016 Jun 29; 80(2). PMID: 27351142    Free PMC article.
Epigenetic therapy in gastrointestinal cancer: the right combination.
Eihab Abdelfatah, Zachary Kerner, Nainika Nanda, Nita Ahuja.
Therap Adv Gastroenterol, 2016 Jul 02; 9(4). PMID: 27366224    Free PMC article.
Moving forward with human papillomavirus immunotherapies.
Nicolas Çuburu, John T Schiller.
Hum Vaccin Immunother, 2016 Jul 09; 12(11). PMID: 27388123    Free PMC article.
CHAI and LATAIE: new genetic diseases of CTLA-4 checkpoint insufficiency.
Bernice Lo, Jill M Fritz, +3 authors, Michael J Lenardo.
Blood, 2016 Jul 16; 128(8). PMID: 27418640    Free PMC article.
CD137-CRDI is not necessary in the role of contacting its natural ligand.
Ling Yi, Zhuohong Yan, +3 authors, Hongtao Zhang.
Immunol Cell Biol, 2016 Jul 20; 95(1). PMID: 27430526
Stereotactic Ablative Radiation Therapy Combined With Immunotherapy for Solid Tumors.
Eric D Brooks, Jonathan E Schoenhals, +4 authors, James W Welsh.
Cancer J, 2016 Jul 22; 22(4). PMID: 27441745    Free PMC article.
High-Resolution PET Imaging with Therapeutic Antibody-based PD-1/PD-L1 Checkpoint Tracers.
Michael Hettich, Friederike Braun, +2 authors, Gabriele Niedermann.
Theranostics, 2016 Jul 23; 6(10). PMID: 27446497    Free PMC article.
Highly Cited.
Challenges of Using High-Dose Fractionation Radiotherapy in Combination Therapy.
Ying-Chieh Yang, Chi-Shiun Chiang.
Front Oncol, 2016 Jul 23; 6. PMID: 27446811    Free PMC article.
Magneto-nanosensor platform for probing low-affinity protein-protein interactions and identification of a low-affinity PD-L1/PD-L2 interaction.
Jung-Rok Lee, Daniel J B Bechstein, +5 authors, Shan X Wang.
Nat Commun, 2016 Jul 23; 7. PMID: 27447090    Free PMC article.
Personalized cancer vaccines: Targeting the cancer mutanome.
Xiuli Zhang, Piyush K Sharma, S Peter Goedegebuure, William E Gillanders.
Vaccine, 2016 Jul 28; 35(7). PMID: 27449681    Free PMC article.
Immuno-oncology combinations: raising the tail of the survival curve.
Samuel J Harris, Jessica Brown, Juanita Lopez, Timothy A Yap.
Cancer Biol Med, 2016 Jul 28; 13(2). PMID: 27458526    Free PMC article.
CXCL12 promoter methylation and PD-L1 expression as prognostic biomarkers in prostate cancer patients.
Diane Goltz, Emily Eva Holmes, +8 authors, Dimo Dietrich.
Oncotarget, 2016 Jul 28; 7(33). PMID: 27462860    Free PMC article.
Tetraspanin CD81, a modulator of immune suppression in cancer and metastasis.
Felipe Vences-Catalán, Ranjani Rajapaksa, +4 authors, Shoshana Levy.
Oncoimmunology, 2016 Jul 29; 5(5). PMID: 27467918    Free PMC article.
A novel dendritic cell targeting HPV16 E7 synthetic vaccine in combination with PD-L1 blockade elicits therapeutic antitumor immunity in mice.
Zhida Liu, Hang Zhou, +2 authors, Mingzhao Zhu.
Oncoimmunology, 2016 Jul 30; 5(6). PMID: 27471615    Free PMC article.
Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy.
Aitziber Buqué, Norma Bloy, +10 authors, Lorenzo Galluzzi.
Oncoimmunology, 2016 Jul 30; 5(6). PMID: 27471617    Free PMC article.
Efficacy of β-Lactam-plus-Macrolide Combination Therapy in a Mouse Model of Lethal Pneumococcal Pneumonia.
Daisuke Yoshioka, Chiaki Kajiwara, +4 authors, Kazuhiro Tateda.
Antimicrob Agents Chemother, 2016 Aug 03; 60(10). PMID: 27480866    Free PMC article.
Chemo-immunotherapy induces tumor regression in a mouse model of spontaneous mammary carcinogenesis.
Eleonora Aricò, Paola Sestili, +6 authors, Enrico Proietti.
Oncotarget, 2016 Aug 04; 7(37). PMID: 27486759    Free PMC article.
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy.
Lewis Zhichang Shi, Tihui Fu, +7 authors, Padmanee Sharma.
Nat Commun, 2016 Aug 09; 7. PMID: 27498556    Free PMC article.
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.
Se Jin Im, Masao Hashimoto, +13 authors, Rafi Ahmed.
Nature, 2016 Aug 09; 537(7620). PMID: 27501248    Free PMC article.
Highly Cited.
Integrated genomic analysis of recurrence-associated small non-coding RNAs in oesophageal cancer.
Hee-Jin Jang, Hyun-Sung Lee, +23 authors, Ju-Seog Lee.
Gut, 2016 Aug 11; 66(2). PMID: 27507904    Free PMC article.
Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy.
Chunbai He, Xiaopin Duan, +4 authors, Wenbin Lin.
Nat Commun, 2016 Aug 18; 7. PMID: 27530650    Free PMC article.
Highly Cited.
Discovery of peptide inhibitors targeting human programmed death 1 (PD-1) receptor.
Qiao Li, Lina Quan, +7 authors, Honglin Li.
Oncotarget, 2016 Aug 18; 7(40). PMID: 27533458    Free PMC article.
Immune checkpoints and rheumatic diseases: what can cancer immunotherapy teach us?
Michiel van der Vlist, Jurgen Kuball, Timothy R D Radstake, Linde Meyaard.
Nat Rev Rheumatol, 2016 Aug 20; 12(10). PMID: 27539666
Digitally deconvolving the tumor microenvironment.
Dvir Aran, Atul J Butte.
Genome Biol, 2016 Aug 24; 17(1). PMID: 27549319    Free PMC article.
Inflammation-Triggered Cancer Immunotherapy by Programmed Delivery of CpG and Anti-PD1 Antibody.
Chao Wang, Wujin Sun, +2 authors, Zhen Gu.
Adv Mater, 2016 Oct 21; 28(40). PMID: 27558441    Free PMC article.
The European Organization for Research and Treatment of Cancer perspective on designing clinical trials with immune therapeutics.
Jessica Menis, Saskia Litière, Konstantinos Tryfonidis, Vassilis Golfinopoulos.
Ann Transl Med, 2016 Aug 27; 4(14). PMID: 27563654    Free PMC article.
γδ T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation.
Donnele Daley, Constantinos Pantelis Zambirinis, +17 authors, George Miller.
Cell, 2016 Aug 30; 166(6). PMID: 27569912    Free PMC article.
Highly Cited.
Fatal attraction: TICs and MDSCs.
Thomas Welte, Jeffrey M Rosen, Xiang H-F Zhang.
Cell Cycle, 2016 Oct 18; 15(19). PMID: 27574951    Free PMC article.
Chlorin-Based Nanoscale Metal-Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy.
Kuangda Lu, Chunbai He, +4 authors, Wenbin Lin.
J Am Chem Soc, 2016 Aug 31; 138(38). PMID: 27575718    Free PMC article.
T-cell exhaustion: understanding the interface of chronic viral and autoinflammatory diseases.
Eoin F McKinney, Kenneth Gc Smith.
Immunol Cell Biol, 2016 Sep 01; 94(10). PMID: 27577866
Investigation of PD-L1 Biomarker Testing Methods for PD-1 Axis Inhibition in Non-squamous Non-small Cell Lung Cancer.
Brandon S Sheffield, Regan Fulton, +15 authors, Diana N Ionescu.
J Histochem Cytochem, 2016 Sep 04; 64(10). PMID: 27591097    Free PMC article.
Gel-Trapped Lymphorganogenic Chemokines Trigger Artificial Tertiary Lymphoid Organs and Mount Adaptive Immune Responses In Vivo.
Yuka Kobayashi, Takeshi Watanabe.
Front Immunol, 2016 Sep 07; 7. PMID: 27597851    Free PMC article.
Mass spectrometric analysis of the HLA class I peptidome of melanoma cell lines as a promising tool for the identification of putative tumor-associated HLA epitopes.
Andreas Gloger, Danilo Ritz, Tim Fugmann, Dario Neri.
Cancer Immunol Immunother, 2016 Oct 21; 65(11). PMID: 27600516    Free PMC article.
Immunotherapy in human colorectal cancer: Challenges and prospective.
Xuan Sun, Jian Suo, Jun Yan.
World J Gastroenterol, 2016 Sep 09; 22(28). PMID: 27605872    Free PMC article.
Embracing rejection: Immunologic trends in brain metastasis.
S Harrison Farber, Vadim Tsvankin, +6 authors, Peter E Fecci.
Oncoimmunology, 2016 Sep 14; 5(7). PMID: 27622023    Free PMC article.
Serine and one-carbon metabolism in cancer.
Ming Yang, Karen H Vousden.
Nat Rev Cancer, 2016 Sep 17; 16(10). PMID: 27634448
Highly Cited. Review.
Heralding a new paradigm in 3D tumor modeling.
Eliza L S Fong, Daniel A Harrington, Mary C Farach-Carson, Hanry Yu.
Biomaterials, 2016 Sep 19; 108. PMID: 27639438    Free PMC article.
Lack of immunoediting in murine pancreatic cancer reversed with neoantigen.
Rebecca A Evans, Mark S Diamond, +10 authors, Robert H Vonderheide.
JCI Insight, 2016 Sep 20; 1(14). PMID: 27642636    Free PMC article.
Highly Cited.
PI3Kγ is a molecular switch that controls immune suppression.
Megan M Kaneda, Karen S Messer, +20 authors, Judith A Varner.
Nature, 2016 Nov 01; 539(7629). PMID: 27642729    Free PMC article.
Highly Cited.
Circulating and disseminated tumour cells - mechanisms of immune surveillance and escape.
Malte Mohme, Sabine Riethdorf, Klaus Pantel.
Nat Rev Clin Oncol, 2016 Nov 03; 14(3). PMID: 27644321
Highly Cited. Review.
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.
Jianjun Gao, Lewis Zhichang Shi, +13 authors, Padmanee Sharma.
Cell, 2016 Sep 27; 167(2). PMID: 27667683    Free PMC article.
Highly Cited.
Local delivery of checkpoints antibodies.
Chao Wang, Yanqi Ye, Zhen Gu.
Hum Vaccin Immunother, 2016 Sep 27; 13(1). PMID: 27668759    Free PMC article.
Methylation of RAD51B, XRCC3 and other homologous recombination genes is associated with expression of immune checkpoints and an inflammatory signature in squamous cell carcinoma of the head and neck, lung and cervix.
Damian T Rieke, Sebastian Ochsenreither, +4 authors, Ulrich Keilholz.
Oncotarget, 2016 Sep 30; 7(46). PMID: 27683114    Free PMC article.
T-Cell-Based Immunotherapy for Osteosarcoma: Challenges and Opportunities.
Zhan Wang, Binghao Li, Yingqing Ren, Zhaoming Ye.
Front Immunol, 2016 Sep 30; 7. PMID: 27683579    Free PMC article.
Predicting PD-L1 expression on human cancer cells using next-generation sequencing information in computational simulation models.
Emily A Lanzel, M Paula Gomez Hernandez, +9 authors, Kim A Brogden.
Cancer Immunol Immunother, 2016 Oct 01; 65(12). PMID: 27688163    Free PMC article.
Genomic Approaches to Understanding Response and Resistance to Immunotherapy.
David A Braun, Kelly P Burke, Eliezer M Van Allen.
Clin Cancer Res, 2016 Oct 05; 22(23). PMID: 27698000    Free PMC article.
Deep tissue imaging: a review from a preclinical cancer research perspective.
Annette Feuchtinger, Axel Walch, Michael Dobosz.
Histochem Cell Biol, 2016 Oct 06; 146(6). PMID: 27704211
Indoleamine 2,3-dioxygenase regulates anti-tumor immunity in lung cancer by metabolic reprogramming of immune cells in the tumor microenvironment.
Cara C Schafer, Yong Wang, +6 authors, Jessy S Deshane.
Oncotarget, 2016 Oct 06; 7(46). PMID: 27705910    Free PMC article.
Regulation of T cell signalling by membrane lipids.
Wei Wu, Xiaoshan Shi, Chenqi Xu.
Nat Rev Immunol, 2016 Oct 27; 16(11). PMID: 27721483
Comparison of tumor-infiltrating lymphocytes between primary and metastatic tumors in breast cancer patients.
Rin Ogiya, Naoki Niikura, +13 authors, Yutaka Tokuda.
Cancer Sci, 2016 Oct 12; 107(12). PMID: 27727484    Free PMC article.
Metabolite and Microbiome Interplay in Cancer Immunotherapy.
Caroline H Johnson, Mary E Spilker, +2 authors, Gary Siuzdak.
Cancer Res, 2016 Nov 03; 76(21). PMID: 27729325    Free PMC article.
Nivolumab monotherapy in recurrent metastatic urothelial carcinoma (CheckMate 032): a multicentre, open-label, two-stage, multi-arm, phase 1/2 trial.
Padmanee Sharma, Margaret K Callahan, +15 authors, Jonathan E Rosenberg.
Lancet Oncol, 2016 Oct 14; 17(11). PMID: 27733243    Free PMC article.
Highly Cited.
Immune Therapy for Prostate Cancer.
Oladapo Yeku, Susan F Slovin.
Cancer J, 2016 Oct 18; 22(5). PMID: 27749327    Free PMC article.
The concept of immune surveillance against tumors. The first theories.
Domenico Ribatti.
Oncotarget, 2016 Oct 21; 8(4). PMID: 27764780    Free PMC article.
Highly Cited. Review.
Radiotherapy: Changing the Game in Immunotherapy.
Sandra Demaria, C Norman Coleman, Silvia C Formenti.
Trends Cancer, 2016 Oct 25; 2(6). PMID: 27774519    Free PMC article.
Highly Cited. Review.
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.
Kelly D Moynihan, Cary F Opel, +19 authors, Darrell J Irvine.
Nat Med, 2016 Nov 01; 22(12). PMID: 27775706    Free PMC article.
Highly Cited.
Integrating precision cancer medicine into healthcare-policy, practice, and research challenges.
Gabrielle Bertier, Jian Carrot-Zhang, Vassilis Ragoussis, Yann Joly.
Genome Med, 2016 Oct 26; 8(1). PMID: 27776531    Free PMC article.
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.
Kristen E Pauken, Morgan A Sammons, +16 authors, E John Wherry.
Science, 2016 Oct 30; 354(6316). PMID: 27789795    Free PMC article.
Highly Cited.
Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy.
Ju Yeon Lee, Hyun Tae Lee, +11 authors, Yong-Seok Heo.
Nat Commun, 2016 Nov 01; 7. PMID: 27796306    Free PMC article.
Highly Cited.
Systemic sarcoidosis first manifesting in a tattoo in the setting of immune checkpoint inhibition.
Charissa Kim, Jianjun Gao, Vickie R Shannon, Arlene Siefker-Radtke.
BMJ Case Rep, 2016 Nov 01; 2016. PMID: 27797838    Free PMC article.
Diacylglycerol Kinases (DGKs): Novel Targets for Improving T Cell Activity in Cancer.
Matthew J Riese, Edmund K Moon, Bryon D Johnson, Steven M Albelda.
Front Cell Dev Biol, 2016 Nov 02; 4. PMID: 27800476    Free PMC article.
Antagonizing programmed death-1 and programmed death ligand-1 as a therapeutic approach for gastric cancer.
Xiaojun Liu, Zhongxia Yang, Olivier Latchoumanin, Liang Qiao.
Therap Adv Gastroenterol, 2016 Nov 03; 9(6). PMID: 27803740    Free PMC article.
Cell Signaling Pathways That Regulate Antigen Presentation.
Randy R Brutkiewicz.
J Immunol, 2016 Nov 09; 197(8). PMID: 27824592    Free PMC article.
Gene-expression profiling to predict responsiveness to immunotherapy.
N B Jamieson, A V Maker.
Cancer Gene Ther, 2016 Nov 12; 24(3). PMID: 27834354    Free PMC article.
Making urothelial carcinomas less immune to immunotherapy.
Jorge D Ramos, Evan Y Yu.
Urol Oncol, 2016 Nov 12; 34(12). PMID: 27836245    Free PMC article.
Emerging role of immunotherapy in urothelial carcinoma-Immunobiology/biomarkers.
Randy F Sweis, Matthew D Galsky.
Urol Oncol, 2016 Nov 12; 34(12). PMID: 27836246    Free PMC article.
Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015.
Paolo A Ascierto, Sanjiv Agarwala, +33 authors, Magdalena Thurin.
J Transl Med, 2016 Nov 17; 14(1). PMID: 27846884    Free PMC article.
PD-1 Suppresses Development of Humoral Responses That Protect against Tn-Bearing Tumors.
Marcela A Haro, Chad A Littrell, +2 authors, Karen M Haas.
Cancer Immunol Res, 2016 Nov 20; 4(12). PMID: 27856425    Free PMC article.
The CD8 T-cell response during tolerance induction in liver transplantation.
Yik Chun Wong, Geoffrey W McCaughan, David G Bowen, Patrick Bertolino.
Clin Transl Immunology, 2016 Nov 22; 5(10). PMID: 27867515    Free PMC article.
Improved proliferation of antigen-specific cytolytic T lymphocytes using a multimodal nanovaccine.
Bo Li, Michael Siuta, +10 authors, Wellington Pham.
Int J Nanomedicine, 2016 Nov 30; 11. PMID: 27895483    Free PMC article.
Adapt, Recycle, and Move on: Proteostasis and Trafficking Mechanisms in Melanoma.
Seyma Demirsoy, Shaun Martin, Hannelore Maes, Patrizia Agostinis.
Front Oncol, 2016 Nov 30; 6. PMID: 27896217    Free PMC article.
Integration of genomics and histology revises diagnosis and enables effective therapy of refractory cancer of unknown primary with PDL1 amplification.
Stefan Gröschel, Martin Bommer, +20 authors, Stefan Fröhling.
Cold Spring Harb Mol Case Stud, 2016 Dec 03; 2(6). PMID: 27900363    Free PMC article.
Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations.
Daniel Sanghoon Shin, Jesse M Zaretsky, +24 authors, Antoni Ribas.
Cancer Discov, 2016 Dec 03; 7(2). PMID: 27903500    Free PMC article.
Highly Cited.
Robust detection of immune transcripts in FFPE samples using targeted RNA sequencing.
Benjamin E Paluch, Sean T Glenn, +14 authors, Carl D Morrison.
Oncotarget, 2016 Dec 03; 8(2). PMID: 27911273    Free PMC article.
Checkpoint inhibition in myeloma.
Don M Benson.
Hematology Am Soc Hematol Educ Program, 2016 Dec 04; 2016(1). PMID: 27913525    Free PMC article.
The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer.
Jennifer L Hsu, Mien-Chie Hung.
Cancer Metastasis Rev, 2016 Dec 04; 35(4). PMID: 27913999    Free PMC article.
Hijacker of the Antitumor Immune Response: Autophagy Is Showing Its Worst Facet.
Elodie Viry, Muhammad Zaeem Noman, +6 authors, Bassam Janji.
Front Oncol, 2016 Dec 06; 6. PMID: 27917371    Free PMC article.
Diversity and collaboration for effective immunotherapy.
Karolina Palucka, Jacques Banchereau.
Nat Med, 2016 Dec 07; 22(12). PMID: 27923023
The Role of Cancer-Associated Fibroblasts and Fibrosis in Liver Cancer.
Silvia Affo, Le-Xing Yu, Robert F Schwabe.
Annu Rev Pathol, 2016 Dec 14; 12. PMID: 27959632    Free PMC article.
Highly Cited. Review.
Photodynamic Therapy Mediated by Nontoxic Core-Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer.
Xiaopin Duan, Christina Chan, +3 authors, Wenbin Lin.
J Am Chem Soc, 2016 Dec 16; 138(51). PMID: 27976881    Free PMC article.
Immune Checkpoint Blockade in Hepatocellular Carcinoma: 2017 Update.
M Kudo.
Liver Cancer, 2016 Dec 21; 6(1). PMID: 27995082    Free PMC article.
Identification of immunotherapeutic targets by genomic profiling of rectal NET metastases.
Zeynep Koşaloğlu, Inka Zörnig, +7 authors, Dirk Jäger.
Oncoimmunology, 2016 Dec 22; 5(11). PMID: 27999735    Free PMC article.
The interplay of epigenetic therapy and immunity in locally recurrent or metastatic estrogen receptor-positive breast cancer: Correlative analysis of ENCORE 301, a randomized, placebo-controlled phase II trial of exemestane with or without entinostat.
Yusuke Tomita, Min-Jung Lee, +5 authors, Jane B Trepel.
Oncoimmunology, 2016 Dec 22; 5(11). PMID: 27999738    Free PMC article.
PD-L1 Is Not Constitutively Expressed on Tasmanian Devil Facial Tumor Cells but Is Strongly Upregulated in Response to IFN-γ and Can Be Expressed in the Tumor Microenvironment.
Andrew S Flies, A Bruce Lyons, +5 authors, John D Hayball.
Front Immunol, 2016 Dec 27; 7. PMID: 28018348    Free PMC article.
Immune targets and neoantigens for cancer immunotherapy and precision medicine.
Rong-Fu Wang, Helen Y Wang.
Cell Res, 2016 Dec 28; 27(1). PMID: 28025978    Free PMC article.
Highly Cited. Review.
Gene Expression Differences in Prostate Cancers between Young and Old Men.
Yuanchun Ding, Huiqing Wu, +8 authors, Susan L Neuhausen.
PLoS Genet, 2016 Dec 28; 12(12). PMID: 28027300    Free PMC article.
Genetically engineered mouse models in oncology research and cancer medicine.
Kelly Kersten, Karin E de Visser, Martine H van Miltenburg, Jos Jonkers.
EMBO Mol Med, 2016 Dec 29; 9(2). PMID: 28028012    Free PMC article.
Highly Cited. Review.
Regulatory T Cells in Endemic Burkitt Lymphoma Patients Are Associated with Poor Outcomes: A Prospective, Longitudinal Study.
Emily Parsons, Juliana A Otieno, +5 authors, Ann M Moormann.
PLoS One, 2016 Dec 30; 11(12). PMID: 28033393    Free PMC article.
First-in-Human Phase I Study of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase-1 Epacadostat (INCB024360) in Patients with Advanced Solid Malignancies.
Gregory L Beatty, Peter J O'Dwyer, +8 authors, Thomas F Gajewski.
Clin Cancer Res, 2017 Jan 06; 23(13). PMID: 28053021    Free PMC article.
Highly Cited.
Translating genomic profiling to gastrointestinal cancer treatment.
Kazuto Harada, Dilsa Mizrak Kaya, +3 authors, Jaffer A Ajani.
Future Oncol, 2017 Jan 10; 13(10). PMID: 28067073    Free PMC article.
SOCS1 favors the epithelial-mesenchymal transition in melanoma, promotes tumor progression and prevents antitumor immunity by PD-L1 expression.
R Berzaghi, V S C Maia, +8 authors, L R Travassos.
Sci Rep, 2017 Jan 13; 7. PMID: 28079159    Free PMC article.
Is immunotherapy here to stay in multiple myeloma?
Paula Rodríguez-Otero, Bruno Paiva, +2 authors, Jesús F San Miguel.
Haematologica, 2017 Jan 14; 102(3). PMID: 28082344    Free PMC article.
Determinants of metastatic competency in colorectal cancer.
Daniele V F Tauriello, Alexandre Calon, Enza Lonardo, Eduard Batlle.
Mol Oncol, 2017 Jan 14; 11(1). PMID: 28085225    Free PMC article.
Tumour-associated macrophages as treatment targets in oncology.
Alberto Mantovani, Federica Marchesi, +2 authors, Paola Allavena.
Nat Rev Clin Oncol, 2017 Jan 25; 14(7). PMID: 28117416    Free PMC article.
Highly Cited. Review.
PD-1, PD-L1 (B7-H1) and Tumor-Site Immune Modulation Therapy: The Historical Perspective.
Jun Wang, Ruirong Yuan, +3 authors, Zihai Li.
J Hematol Oncol, 2017 Jan 27; 10(1). PMID: 28122590    Free PMC article.
Highly Cited. Review.
Clinical implication of tumor-associated and immunological parameters in melanoma patients treated with ipilimumab.
V Damuzzo, S Solito, +6 authors, S Mandruzzato.
Oncoimmunology, 2017 Jan 27; 5(12). PMID: 28123888    Free PMC article.
Host controls of HIV broadly neutralizing antibody development.
Garnett Kelsoe, Barton F Haynes.
Immunol Rev, 2017 Jan 31; 275(1). PMID: 28133807    Free PMC article.
Highly Cited. Review.
Recent developments in the management of germ cell tumors.
Pavlos Msaouel, Mehmet A Bilen, +3 authors, Shi-Ming Tu.
Curr Opin Oncol, 2017 Feb 06; 29(3). PMID: 28151756    Free PMC article.
Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies.
Elie Dheilly, Valéry Moine, +12 authors, Krzysztof Masternak.
Mol Ther, 2017 Feb 06; 25(2). PMID: 28153099    Free PMC article.
Adoptive Transfer of Invariant NKT Cells as Immunotherapy for Advanced Melanoma: A Phase I Clinical Trial.
Mark A Exley, Phillip Friedlander, +15 authors, Steven P Balk.
Clin Cancer Res, 2017 Feb 15; 23(14). PMID: 28193627    Free PMC article.
Highly Cited.
Inactivation of Interferon Receptor Promotes the Establishment of Immune Privileged Tumor Microenvironment.
Kanstantsin V Katlinski, Jun Gui, +14 authors, Serge Y Fuchs.
Cancer Cell, 2017 Feb 16; 31(2). PMID: 28196594    Free PMC article.
Highly Cited.
Tumor-infiltrating lymphocyte composition, organization and PD-1/ PD-L1 expression are linked in breast cancer.
Laurence Buisseret, Soizic Garaud, +14 authors, Karen Willard-Gallo.
Oncoimmunology, 2017 Feb 16; 6(1). PMID: 28197375    Free PMC article.
Highly Cited.
The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200.
Muhammad Zaeem Noman, Bassam Janji, +6 authors, Salem Chouaib.
Oncoimmunology, 2017 Feb 16; 6(1). PMID: 28197390    Free PMC article.
Highly Cited.
Bidirectional Crosstalk between Lymphatic Endothelial Cell and T Cell and Its Implications in Tumor Immunity.
Kim Pin Yeo, Veronique Angeli.
Front Immunol, 2017 Feb 22; 8. PMID: 28220121    Free PMC article.
Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma.
Suzanne George, Diana Miao, +13 authors, Eliezer M Van Allen.
Immunity, 2017 Feb 24; 46(2). PMID: 28228279    Free PMC article.
Highly Cited.
Immune modulation by dendritic-cell-based cancer vaccines.
Chaitanya Kumar, Sakshi Kohli, +4 authors, Bandana Sharan.
J Biosci, 2017 Feb 24; 42(1). PMID: 28229976
Structure-guided development of a high-affinity human Programmed Cell Death-1: Implications for tumor immunotherapy.
Eszter Lázár-Molnár, Lisa Scandiuzzi, +7 authors, Steven C Almo.
EBioMedicine, 2017 Feb 25; 17. PMID: 28233730    Free PMC article.
Combination immunotherapy: a road map.
Patrick A Ott, F Stephen Hodi, +2 authors, Jedd D Wolchok.
J Immunother Cancer, 2017 Feb 28; 5. PMID: 28239469    Free PMC article.
Highly Cited. Review.
PD-L1 is a diverse molecule regulating both tumor-intrinsic signaling and adaptive immunosuppression.
Kim A Brogden, Shireen Vali, Taher Abbasi.
Transl Cancer Res, 2017 Feb 28; 5(Suppl 7). PMID: 28239565    Free PMC article.
Development of Novel ImmunoPET Tracers to Image Human PD-1 Checkpoint Expression on Tumor-Infiltrating Lymphocytes in a Humanized Mouse Model.
Arutselvan Natarajan, Aaron T Mayer, +2 authors, Sanjiv Sam Gambhir.
Mol Imaging Biol, 2017 Mar 02; 19(6). PMID: 28247187    Free PMC article.
Cytokine biomarkers to predict antitumor responses to nivolumab suggested in a phase 2 study for advanced melanoma.
Naoya Yamazaki, Yoshio Kiyohara, +11 authors, Hideaki Tahara.
Cancer Sci, 2017 Mar 08; 108(5). PMID: 28266140    Free PMC article.
Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy.
Matthias A Oberli, Andreas M Reichmuth, +6 authors, Daniel Blankschtein.
Nano Lett, 2017 Mar 10; 17(3). PMID: 28273716    Free PMC article.
Highly Cited.
T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition.
Enfu Hui, Jeanne Cheung, +8 authors, Ronald D Vale.
Science, 2017 Mar 11; 355(6332). PMID: 28280247    Free PMC article.
Highly Cited.
Obstacles Posed by the Tumor Microenvironment to T cell Activity: A Case for Synergistic Therapies.
Kristin G Anderson, Ingunn M Stromnes, Philip D Greenberg.
Cancer Cell, 2017 Mar 16; 31(3). PMID: 28292435    Free PMC article.
Highly Cited. Review.
Epitope mapping reveals the binding mechanism of a functional antibody cross-reactive to both human and murine programmed death 1.
Dong Li, Jianqing Xu, +5 authors, Jing Li.
MAbs, 2017 Mar 17; 9(4). PMID: 28300475    Free PMC article.
A Comprehensive Guide to the MAGE Family of Ubiquitin Ligases.
Anna K Lee, Patrick Ryan Potts.
J Mol Biol, 2017 Mar 17; 429(8). PMID: 28300603    Free PMC article.
DGK-α: A Checkpoint in Cancer-Mediated Immuno-Inhibition and Target for Immunotherapy.
Elfriede Noessner.
Front Cell Dev Biol, 2017 Mar 21; 5. PMID: 28316970    Free PMC article.
Role of AHR and HIF-1α in Glioblastoma Metabolism.
Galina Gabriely, Michael A Wheeler, Maisa C Takenaka, Francisco J Quintana.
Trends Endocrinol Metab, 2017 Mar 21; 28(6). PMID: 28318896    Free PMC article.
Effective combinatorial immunotherapy for castration-resistant prostate cancer.
Xin Lu, James W Horner, +11 authors, Ronald A DePinho.
Nature, 2017 Mar 23; 543(7647). PMID: 28321130    Free PMC article.
Highly Cited.
Synthetic nanovaccines for immunotherapy.
Min Luo, Layla Z Samandi, +2 authors, Jinming Gao.
J Control Release, 2017 Mar 25; 263. PMID: 28336379    Free PMC article.
PD-L1 is commonly expressed and transcriptionally regulated by STAT3 and MYC in ALK-negative anaplastic large-cell lymphoma.
V Atsaves, N Tsesmetzis, +8 authors, G Z Rassidakis.
Leukemia, 2017 Mar 28; 31(7). PMID: 28344319
Highly Cited.
An immunogenic WT1-derived peptide that induces T cell response in the context of HLA-A*02:01 and HLA-A*24:02 molecules.
Tao Dao, Tatyana Korontsvit, +4 authors, David A Scheinberg.
Oncoimmunology, 2017 Mar 28; 6(2). PMID: 28344864    Free PMC article.
VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer.
Jianjun Gao, John F Ward, +16 authors, Padmanee Sharma.
Nat Med, 2017 Mar 28; 23(5). PMID: 28346412    Free PMC article.
Highly Cited.
Stratification of Pancreatic Ductal Adenocarcinoma: Combinatorial Genetic, Stromal, and Immunologic Markers.
Erik S Knudsen, Paris Vail, +9 authors, Agnieszka K Witkiewicz.
Clin Cancer Res, 2017 Mar 30; 23(15). PMID: 28348045    Free PMC article.
Highly Cited.
Prediction of Response in Melanoma Therapy by Systemic Inflammatory Response - One Size Fits Not All.
Georg Richtig, Martin Pichler.
EBioMedicine, 2017 Apr 04; 18. PMID: 28366295    Free PMC article.
Strategies for Increasing Pancreatic Tumor Immunogenicity.
Burles A Johnson, Mark Yarchoan, +2 authors, Elizabeth M Jaffee.
Clin Cancer Res, 2017 Apr 05; 23(7). PMID: 28373364    Free PMC article.
UV-induced somatic mutations elicit a functional T cell response in the YUMMER1.7 mouse melanoma model.
Jake Wang, Curtis J Perry, +6 authors, Marcus Bosenberg.
Pigment Cell Melanoma Res, 2017 Apr 06; 30(4). PMID: 28379630    Free PMC article.
Highly Cited.
Vaccination with poly(IC:LC) and peptide-pulsed autologous dendritic cells in patients with pancreatic cancer.
Shikhar Mehrotra, Carolyn D Britten, +13 authors, David J Cole.
J Hematol Oncol, 2017 Apr 09; 10(1). PMID: 28388966    Free PMC article.
Tumor SQSTM1 (p62) expression and T cells in colorectal cancer.
Keisuke Kosumi, Yohei Masugi, +20 authors, Reiko Nishihara.
Oncoimmunology, 2017 Apr 14; 6(3). PMID: 28405513    Free PMC article.
Antigen Discovery and Therapeutic Targeting in Hematologic Malignancies.
David A Braun, Catherine J Wu.
Cancer J, 2017 Apr 15; 23(2). PMID: 28410299    Free PMC article.
Dendritic Cell Strategies for Eliciting Mutation-Derived Tumor Antigen Responses in Patients.
Sreekumar Balan, John Finnigan, Nina Bhardwaj.
Cancer J, 2017 Apr 15; 23(2). PMID: 28410301    Free PMC article.
Humanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.
Laurent Verkoczy.
Adv Immunol, 2017 Apr 18; 134. PMID: 28413022    Free PMC article.
Elevated frequencies of CD8 T cells expressing PD-1, CTLA-4 and Tim-3 within tumour from perineural squamous cell carcinoma patients.
Richard Linedale, Campbell Schmidt, +4 authors, Graham R Leggatt.
PLoS One, 2017 Apr 20; 12(4). PMID: 28423034    Free PMC article.
Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma.
Jon Bjoern, Rikke Lyngaa, +4 authors, Inge Marie Svane.
Oncotarget, 2017 Apr 21; 8(16). PMID: 28423678    Free PMC article.
Epithelial-to-Mesenchymal Transition Contributes to Immunosuppression in Breast Carcinomas.
Anushka Dongre, Mohammad Rashidian, +4 authors, Robert A Weinberg.
Cancer Res, 2017 Apr 22; 77(15). PMID: 28428275    Free PMC article.
Highly Cited.
Global survey of the immunomodulatory potential of common drugs.
Gregory I Vladimer, Berend Snijder, +13 authors, Giulio Superti-Furga.
Nat Chem Biol, 2017 Apr 25; 13(6). PMID: 28437395    Free PMC article.
Plasmodium parasite as an effective hepatocellular carcinoma antigen glypican-3 delivery vector.
Quan Liu, Yijun Yang, +8 authors, Xiaoping Chen.
Oncotarget, 2017 Apr 28; 8(15). PMID: 28445973    Free PMC article.
Engineering chimeric human and mouse major histocompatibility complex (MHC) class I tetramers for the production of T-cell receptor (TCR) mimic antibodies.
Demin Li, Carol Bentley, +5 authors, Alison H Banham.
PLoS One, 2017 Apr 28; 12(4). PMID: 28448627    Free PMC article.
Necroptosis and Cancer.
Ayaz Najafov, Hongbo Chen, Junying Yuan.
Trends Cancer, 2017 Apr 30; 3(4). PMID: 28451648    Free PMC article.
Safety and antitumor activity of the anti-PD-1 antibody pembrolizumab in patients with recurrent carcinoma of the anal canal.
P A Ott, S A Piha-Paul, +13 authors, J Bennouna.
Ann Oncol, 2017 Apr 30; 28(5). PMID: 28453692    Free PMC article.
Highly Cited.
Multivalent bi-specific nanobioconjugate engager for targeted cancer immunotherapy.
Hengfeng Yuan, Wen Jiang, +9 authors, Betty Y S Kim.
Nat Nanotechnol, 2017 May 02; 12(8). PMID: 28459470
Radiation improves antitumor effect of immune checkpoint inhibitor in murine hepatocellular carcinoma model.
Kyoung-Jin Kim, Ji-Hye Kim, +3 authors, Jinsil Seong.
Oncotarget, 2017 May 04; 8(25). PMID: 28465485    Free PMC article.
Phase I Trial of Intratumoral Injection of CCL21 Gene-Modified Dendritic Cells in Lung Cancer Elicits Tumor-Specific Immune Responses and CD8+ T-cell Infiltration.
Jay M Lee, Mi-Heon Lee, +23 authors, Steven M Dubinett.
Clin Cancer Res, 2017 May 05; 23(16). PMID: 28468947    Free PMC article.
C3d regulates immune checkpoint blockade and enhances antitumor immunity.
Jeffrey L Platt, Inês Silva, +5 authors, Marilia Cascalho.
JCI Insight, 2017 May 05; 2(9). PMID: 28469081    Free PMC article.
TSNAD: an integrated software for cancer somatic mutation and tumour-specific neoantigen detection.
Zhan Zhou, Xingzheng Lyu, +6 authors, Shuqing Chen.
R Soc Open Sci, 2017 May 10; 4(4). PMID: 28484631    Free PMC article.
Diagnostic and Therapeutic Potential of MicroRNAs in Lung Cancer.
Kentaro Inamura.
Cancers (Basel), 2017 May 10; 9(5). PMID: 28486396    Free PMC article.
Recent advances in preoperative management of esophageal adenocarcinoma.
Kazuto Harada, Dilsa Mizrak Kaya, Hideo Baba, Jaffer A Ajani.
F1000Res, 2017 May 12; 6. PMID: 28491289    Free PMC article.
Current status of chimeric antigen receptor engineered T cell-based and immune checkpoint blockade-based cancer immunotherapies.
Upendra P Hegde, Bijay Mukherji.
Cancer Immunol Immunother, 2017 May 13; 66(9). PMID: 28497159    Free PMC article.
Preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma.
Abhishek D Garg, Lien Vandenberk, +5 authors, Patrizia Agostinis.
Oncoimmunology, 2017 May 17; 6(4). PMID: 28507806    Free PMC article.
Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy.
Sacha Gnjatic, Vincenzo Bronte, +13 authors, Lisa H Butterfield.
J Immunother Cancer, 2017 May 19; 5. PMID: 28515944    Free PMC article.
Highly Cited. Review.
Japanese Kampo medicine ninjin'yoeito synergistically enhances tumor vaccine effects mediated by CD8+ T cells.
Shun Takaku, Masumi Shimizu, Hidemi Takahashi.
Oncol Lett, 2017 May 23; 13(5). PMID: 28529575    Free PMC article.
PD-L1 inhibits acute and chronic pain by suppressing nociceptive neuron activity via PD-1.
Gang Chen, Yong Ho Kim, +7 authors, Ru-Rong Ji.
Nat Neurosci, 2017 May 23; 20(7). PMID: 28530662    Free PMC article.
Converting Lymphoma Cells into Potent Antigen-Presenting Cells for Interferon-Induced Tumor Regression.
Jing Liao, Yan Luan, +7 authors, Yang-Xin Fu.
Cancer Immunol Res, 2017 May 24; 5(7). PMID: 28533311    Free PMC article.
Unravelling the biology of SCLC: implications for therapy.
Joshua K Sabari, Benjamin H Lok, +2 authors, Charles M Rudin.
Nat Rev Clin Oncol, 2017 May 24; 14(9). PMID: 28534531    Free PMC article.
Highly Cited. Review.
The potential of organoids in urological cancer research.
Shangqian Wang, Dong Gao, Yu Chen.
Nat Rev Urol, 2017 May 24; 14(7). PMID: 28534535    Free PMC article.
Intratumoral depletion of regulatory T cells using CD25-targeted photodynamic therapy in a mouse melanoma model induces antitumoral immune responses.
Dong Sun Oh, Heegon Kim, +4 authors, Heung Kyu Lee.
Oncotarget, 2017 May 26; 8(29). PMID: 28537894    Free PMC article.
Interaction of molecular alterations with immune response in melanoma.
Robert A Szczepaniak Sloane, Vancheswaran Gopalakrishnan, +3 authors, Jennifer A Wargo.
Cancer, 2017 May 26; 123(S11). PMID: 28543700    Free PMC article.
Delivering safer immunotherapies for cancer.
Lauren Milling, Yuan Zhang, Darrell J Irvine.
Adv Drug Deliv Rev, 2017 May 27; 114. PMID: 28545888    Free PMC article.
Highly Cited. Review.
Challenges in the delivery of therapies to melanoma brain metastases.
Gautham Gampa, Shruthi Vaidhyanathan, +4 authors, William F Elmquist.
Curr Pharmacol Rep, 2017 May 27; 2(6). PMID: 28546917    Free PMC article.
Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy.
Sandra M Kallert, Stephanie Darbre, +12 authors, Daniel D Pinschewer.
Nat Commun, 2017 May 27; 8. PMID: 28548102    Free PMC article.
Quantification of hepatocellular carcinoma heterogeneity with multiparametric magnetic resonance imaging.
Stefanie J Hectors, Mathilde Wagner, +10 authors, Bachir Taouli.
Sci Rep, 2017 May 28; 7(1). PMID: 28550313    Free PMC article.
Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.
Hong Jiang, Yisel Rivera-Molina, +8 authors, Juan Fueyo.
Cancer Res, 2017 Jun 02; 77(14). PMID: 28566332    Free PMC article.
Highly Cited.
Immunotherapy for Breast Cancer: What Are We Missing?
Robert H Vonderheide, Susan M Domchek, Amy S Clark.
Clin Cancer Res, 2017 Jun 03; 23(11). PMID: 28572258    Free PMC article.
Highly Cited.
Novel "Elements" of Immune Suppression within the Tumor Microenvironment.
Devikala Gurusamy, David Clever, Robert Eil, Nicholas P Restifo.
Cancer Immunol Res, 2017 Jun 04; 5(6). PMID: 28576921    Free PMC article.
Epithelial-mesenchymal transition in cancer metastasis through the lymphatic system.
Mikael C Karlsson, Santiago F Gonzalez, Josefin Welin, Jonas Fuxe.
Mol Oncol, 2017 Jun 08; 11(7). PMID: 28590032    Free PMC article.
Design of short peptides to block BTLA/HVEM interactions for promoting anticancer T-cell responses.
Marta Spodzieja, Sławomir Lach, +8 authors, Sylwia Rodziewicz-Motowidło.
PLoS One, 2017 Jun 09; 12(6). PMID: 28594868    Free PMC article.
DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity.
Claire Vanpouille-Box, Amandine Alard, +7 authors, Sandra Demaria.
Nat Commun, 2017 Jun 10; 8. PMID: 28598415    Free PMC article.
Highly Cited.
Immune deficiency and autoimmunity in patients with CTLA-4 (CD152) mutations.
N Verma, S O Burns, L S K Walker, D M Sansom.
Clin Exp Immunol, 2017 Jun 11; 190(1). PMID: 28600865    Free PMC article.
Dendritic cell-derived exosomes for cancer immunotherapy: hope and challenges.
Hong Tian, Wei Li.
Ann Transl Med, 2017 Jun 13; 5(10). PMID: 28603736    Free PMC article.
Combinatorial antitumor effects of indoleamine 2,3-dioxygenase inhibitor NLG919 and paclitaxel in a murine B16-F10 melanoma model.
Xiangjing Meng, Guangying Du, +6 authors, Jingwei Tian.
Int J Immunopathol Pharmacol, 2017 Jun 13; 30(3). PMID: 28604143    Free PMC article.
Transcriptional and epigenetic regulation of T cell hyporesponsiveness.
Renata M Pereira, Patrick G Hogan, Anjana Rao, Gustavo J Martinez.
J Leukoc Biol, 2017 Jun 14; 102(3). PMID: 28606939    Free PMC article.
Biological Subtypes of Triple-Negative Breast Cancer.
Michael Hubalek, Theresa Czech, Hannes Müller.
Breast Care (Basel), 2017 Jun 15; 12(1). PMID: 28611535    Free PMC article.
Programmed death-ligand 1 (PD-L1) is expressed in a significant number of the uterine cervical carcinomas.
Opal L Reddy, Peter I Shintaku, Neda A Moatamed.
Diagn Pathol, 2017 Jun 19; 12(1). PMID: 28623908    Free PMC article.
Immunotherapy in pancreatic cancer: Unleash its potential through novel combinations.
Songchuan Guo, Merly Contratto, +2 authors, Jennifer Wu.
World J Clin Oncol, 2017 Jun 24; 8(3). PMID: 28638792    Free PMC article.
Drugging the 'undruggable' cancer targets.
Chi V Dang, E Premkumar Reddy, Kevan M Shokat, Laura Soucek.
Nat Rev Cancer, 2017 Jun 24; 17(8). PMID: 28643779    Free PMC article.
Highly Cited. Review.
De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.
Hazem E Ghoneim, Yiping Fan, +8 authors, Ben Youngblood.
Cell, 2017 Jun 27; 170(1). PMID: 28648661    Free PMC article.
Highly Cited.
IFN-γ-related mRNA profile predicts clinical response to PD-1 blockade.
Mark Ayers, Jared Lunceford, +12 authors, Terrill K McClanahan.
J Clin Invest, 2017 Jun 27; 127(8). PMID: 28650338    Free PMC article.
Highly Cited.
Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling.
Lunyi Li, Xingdong Guo, +6 authors, Chenqi Xu.
Proc Natl Acad Sci U S A, 2017 Jul 01; 114(29). PMID: 28659468    Free PMC article.
Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study.
Yong Qin, Mariana Petaccia de Macedo, +24 authors, Sapna P Patel.
Oncoimmunology, 2017 Jul 07; 6(6). PMID: 28680759    Free PMC article.
Increased expression of programmed cell death protein 1 on NK cells inhibits NK-cell-mediated anti-tumor function and indicates poor prognosis in digestive cancers.
Y Liu, Y Cheng, +7 authors, C Ma.
Oncogene, 2017 Jul 12; 36(44). PMID: 28692048    Free PMC article.
Highly Cited.
Of Mice, Dirty Mice, and Men: Using Mice To Understand Human Immunology.
David Masopust, Christine P Sivula, Stephen C Jameson.
J Immunol, 2017 Jul 12; 199(2). PMID: 28696328    Free PMC article.
Highly Cited. Review.
Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.
Qianghu Wang, Baoli Hu, +31 authors, Roel G W Verhaak.
Cancer Cell, 2017 Jul 12; 32(1). PMID: 28697342    Free PMC article.
Highly Cited.
NK Cell Exhaustion.
Jiacheng Bi, Zhigang Tian.
Front Immunol, 2017 Jul 14; 8. PMID: 28702032    Free PMC article.
Highly Cited. Review.
The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome.
Deborah R Caswell, Charles Swanton.
BMC Med, 2017 Jul 19; 15(1). PMID: 28716075    Free PMC article.
Highly Cited. Review.
Preclinical evaluation of NF-κB-triggered dendritic cells expressing the viral oncogenic driver of Merkel cell carcinoma for therapeutic vaccination.
Kerstin F Gerer, Michael Erdmann, +8 authors, Jan Dörrie.
Ther Adv Med Oncol, 2017 Jul 19; 9(7). PMID: 28717398    Free PMC article.
NLRC5/CITA: A Key Player in Cancer Immune Surveillance.
Sayuri Yoshihama, Saptha Vijayan, Tabasum Sidiq, Koichi S Kobayashi.
Trends Cancer, 2017 Jul 19; 3(1). PMID: 28718425    Free PMC article.
Racial Differences in Cancer Susceptibility and Survival: More Than the Color of the Skin?
Berna C Özdemir, Gian-Paolo Dotto.
Trends Cancer, 2017 Jul 19; 3(3). PMID: 28718431    Free PMC article.
Mouse versus Human Neutrophils in Cancer: A Major Knowledge Gap.
Evgeniy B Eruslanov, Sunil Singhal, Steven M Albelda.
Trends Cancer, 2017 Jul 19; 3(2). PMID: 28718445    Free PMC article.
Tumor immunity requires border patrol to fight the enemy within.
Derk Amsen, Pleun Hombrink, Rene A W van Lier.
Nat Immunol, 2017 Jul 20; 18(8). PMID: 28722713
TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence.
Alexandre Reuben, Rachel Gittelman, +37 authors, Jianjun Zhang.
Cancer Discov, 2017 Jul 25; 7(10). PMID: 28733428    Free PMC article.
The Impact of the Tumor Microenvironment on the Properties of Glioma Stem-Like Cells.
Alessandra Audia, Siobhan Conroy, Rainer Glass, Krishna P L Bhat.
Front Oncol, 2017 Jul 26; 7. PMID: 28740831    Free PMC article.
Natural Killer Cell-Based Cancer Immunotherapies: From Immune Evasion to Promising Targeted Cellular Therapies.
Erhard Hofer, Ulrike Koehl.
Front Immunol, 2017 Jul 28; 8. PMID: 28747910    Free PMC article.
PD-L1 induced by IFN-γ from tumor-associated macrophages via the JAK/STAT3 and PI3K/AKT signaling pathways promoted progression of lung cancer.
Xiaohui Zhang, Yuanyuan Zeng, +8 authors, Jian-An Huang.
Int J Clin Oncol, 2017 Jul 28; 22(6). PMID: 28748356
Highly Cited.
Syk inhibitors in clinical development for hematological malignancies.
Delong Liu, Aleksandra Mamorska-Dyga.
J Hematol Oncol, 2017 Jul 30; 10(1). PMID: 28754125    Free PMC article.
Highly Cited. Review.
Cell genomics and immunosuppressive biomarker expression influence PD-L1 immunotherapy treatment responses in HNSCC-a computational study.
Amber M Bates, Emily A Lanzel, +3 authors, Kim A Brogden.
Oral Surg Oral Med Oral Pathol Oral Radiol, 2017 Aug 02; 124(2). PMID: 28756882    Free PMC article.
Intratumoral delivery of inactivated modified vaccinia virus Ankara (iMVA) induces systemic antitumor immunity via STING and Batf3-dependent dendritic cells.
Peihong Dai, Weiyi Wang, +7 authors, Liang Deng.
Sci Immunol, 2017 Aug 02; 2(11). PMID: 28763795    Free PMC article.
Prognostic and predictive values of PD-L1 expression in patients with digestive system cancer: a meta-analysis.
Cong Dai, Meng Wang, +7 authors, Zhijun Dai.
Onco Targets Ther, 2017 Aug 05; 10. PMID: 28769571    Free PMC article.
Immunotherapeutic Strategies for Gastric Carcinoma: A Review of Preclinical and Clinical Recent Development.
Mohamed Abozeid, Antonio Rosato, Roberta Sommaggio.
Biomed Res Int, 2017 Aug 07; 2017. PMID: 28781967    Free PMC article.
Mechanisms that drive inflammatory tumor microenvironment, tumor heterogeneity, and metastatic progression.
Li Yang, P Charles Lin.
Semin Cancer Biol, 2017 Aug 08; 47. PMID: 28782608    Free PMC article.
Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies.
M Anthony Moody, Isabela Pedroza-Pacheco, +17 authors, Barton F Haynes.
Sci Immunol, 2017 Aug 08; 1(1). PMID: 28783677    Free PMC article.
Highly Cited.
Human papillomavirus-driven immune deviation: challenge and novel opportunity for immunotherapy.
Sigrun Smola, Connie Trimble, Peter L Stern.
Ther Adv Vaccines, 2017 Aug 11; 5(3). PMID: 28794879    Free PMC article.
Markers of T Cell Senescence in Humans.
Weili Xu, Anis Larbi.
Int J Mol Sci, 2017 Aug 11; 18(8). PMID: 28796199    Free PMC article.
BET bromodomain inhibitors synergize with ATR inhibitors in melanoma.
Somsundar Veppil Muralidharan, Berglind Osk Einarsdottir, +8 authors, Jonas A Nilsson.
Cell Death Dis, 2017 Aug 11; 8(8). PMID: 28796244    Free PMC article.
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade.
Spencer C Wei, Jacob H Levine, +8 authors, James P Allison.
Cell, 2017 Aug 15; 170(6). PMID: 28803728    Free PMC article.
Highly Cited.
[Basic principles: signaling pathways and checkpoints].
M Preusser.
Radiologe, 2017 Aug 16; 57(10). PMID: 28808733
IL-18 receptor marks functional CD8+ T cells in non-small cell lung cancer.
Eleonora Timperi, Chiara Focaccetti, +11 authors, Vincenzo Barnaba.
Oncoimmunology, 2017 Aug 16; 6(7). PMID: 28811967    Free PMC article.
IgG cooperativity - Is there allostery? Implications for antibody functions and therapeutic antibody development.
Danlin Yang, Rachel Kroe-Barrett, +2 authors, Thomas M Laue.
MAbs, 2017 Aug 17; 9(8). PMID: 28812955    Free PMC article.
CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity.
Marian L Burr, Christina E Sparbier, +21 authors, Mark A Dawson.
Nature, 2017 Aug 17; 549(7670). PMID: 28813417    Free PMC article.
Highly Cited.
β-Adrenergic Signaling in Mice Housed at Standard Temperatures Suppresses an Effector Phenotype in CD8+ T Cells and Undermines Checkpoint Inhibitor Therapy.
Mark J Bucsek, Guanxi Qiao, +11 authors, Elizabeth A Repasky.
Cancer Res, 2017 Aug 19; 77(20). PMID: 28819022    Free PMC article.
Novel prostate cancer immunotherapy with a DNA-encoded anti-prostate-specific membrane antigen monoclonal antibody.
Kar Muthumani, Liron Marnin, +13 authors, David B Weiner.
Cancer Immunol Immunother, 2017 Aug 19; 66(12). PMID: 28819703    Free PMC article.
Immune Dysfunction in Non-Hodgkin Lymphoma: Avenues for New Immunotherapy-Based Strategies.
Lorenzo Falchi.
Curr Hematol Malig Rep, 2017 Aug 20; 12(5). PMID: 28822058
High dose-rate Intra-Operative Radiation Therapy During High Risk Genitourinary Surgery: Initial Observations and a Proposal for its Study in Bladder Cancer.
Max Kates, Meera R Chappidi, +11 authors, Trinity J Bivalacqua.
Bladder Cancer, 2017 Aug 22; 3(3). PMID: 28824947    Free PMC article.
Role of PD-L1 expression as a biomarker for GEP neuroendocrine neoplasm grading.
Elisabetta Cavalcanti, Raffaele Armentano, +2 authors, Maria Lucia Caruso.
Cell Death Dis, 2017 Aug 25; 8(8). PMID: 28837143    Free PMC article.
Rare, high-affinity mouse anti-PD-1 antibodies that function in checkpoint blockade, discovered using microfluidics and molecular genomics.
Adam S Adler, Rena A Mizrahi, +6 authors, David S Johnson.
MAbs, 2017 Aug 29; 9(8). PMID: 28846506    Free PMC article.
Clinical Applications of Immunotherapy Combination Methods and New Opportunities for the Future.
Ece Esin.
Biomed Res Int, 2017 Aug 30; 2017. PMID: 28848761    Free PMC article.
Immuno-oncology Trial Endpoints: Capturing Clinically Meaningful Activity.
Valsamo Anagnostou, Mark Yarchoan, +6 authors, Patrick M Forde.
Clin Cancer Res, 2017 Sep 03; 23(17). PMID: 28864724    Free PMC article.
Multiscale technologies for treatment of ischemic cardiomyopathy.
Morteza Mahmoudi, Mikyung Yu, +5 authors, Omid C Farokhzad.
Nat Nanotechnol, 2017 Sep 07; 12(9). PMID: 28875984    Free PMC article.
miR-31: a key player in CD8 T-cell exhaustion.
Siddheshvar Bhela, Barry T Rouse.
Cell Mol Immunol, 2017 Sep 12; 14(12). PMID: 28890544    Free PMC article.
Making a virtue of necessity: the pleiotropic role of human endogenous retroviruses in cancer.
George Kassiotis, Jonathan P Stoye.
Philos Trans R Soc Lond B Biol Sci, 2017 Sep 13; 372(1732). PMID: 28893944    Free PMC article.
Immunotherapy: Cancer vaccines on the move.
Jacques Banchereau, Karolina Palucka.
Nat Rev Clin Oncol, 2017 Sep 13; 15(1). PMID: 28895570
PD-L1/PD-1 expression and tumor-infiltrating lymphocytes in conjunctival melanoma.
Jinfeng Cao, Niels J Brouwer, +6 authors, Martine J Jager.
Oncotarget, 2017 Sep 15; 8(33). PMID: 28903377    Free PMC article.
Tumor location impacts immune response in mouse models of colon cancer.
Xianda Zhao, Lihua Li, Timothy K Starr, Subbaya Subramanian.
Oncotarget, 2017 Sep 15; 8(33). PMID: 28903381    Free PMC article.
Tumor Resection Recruits Effector T Cells and Boosts Therapeutic Efficacy of Encapsulated Stem Cells Expressing IFNβ in Glioblastomas.
Sung Hugh Choi, Daniel W Stuckey, +7 authors, Khalid Shah.
Clin Cancer Res, 2017 Sep 16; 23(22). PMID: 28912136    Free PMC article.
Complement in cancer: untangling an intricate relationship.
Edimara S Reis, Dimitrios C Mastellos, +2 authors, John D Lambris.
Nat Rev Immunol, 2017 Sep 19; 18(1). PMID: 28920587    Free PMC article.
Highly Cited. Review.
Relationship of tumor PD-L1 (CD274) expression with lower mortality in lung high-grade neuroendocrine tumor.
Kentaro Inamura, Yusuke Yokouchi, +5 authors, Yuichi Ishikawa.
Cancer Med, 2017 Sep 20; 6(10). PMID: 28925087    Free PMC article.
Bacterial outer membrane vesicles suppress tumor by interferon-γ-mediated antitumor response.
Oh Youn Kim, Hyun Taek Park, +5 authors, Yong Song Gho.
Nat Commun, 2017 Sep 22; 8(1). PMID: 28931823    Free PMC article.
Rare cancers: the greatest inequality in cancer research and oncology treatment.
Muhammad A Alvi, Richard H Wilson, Manuel Salto-Tellez.
Br J Cancer, 2017 Sep 22; 117(9). PMID: 28934760    Free PMC article.
A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models.
Binbing Ling, Kathleen Watt, +5 authors, Andrew W B Craig.
Oncotarget, 2017 Sep 25; 8(35). PMID: 28938563    Free PMC article.
Hepatoma-intrinsic CCRK inhibition diminishes myeloid-derived suppressor cell immunosuppression and enhances immune-checkpoint blockade efficacy.
Jingying Zhou, Man Liu, +17 authors, Alfred Sze-Lok Cheng.
Gut, 2017 Sep 25; 67(5). PMID: 28939663    Free PMC article.
PD-1 Blockade Promotes Epitope Spreading in Anticancer CD8+ T Cell Responses by Preventing Fratricidal Death of Subdominant Clones To Relieve Immunodomination.
Arash Memarnejadian, Courtney E Meilleur, +4 authors, S M Mansour Haeryfar.
J Immunol, 2017 Sep 25; 199(9). PMID: 28939757    Free PMC article.
Beyond the Percentages of PD-L1-Positive Tumor Cells: Induced Versus Constitutive PD-L1 Expression in Primary and Metastatic Head and Neck Squamous Cell Carcinoma.
Theresa Scognamiglio, Yao-Tseng Chen.
Head Neck Pathol, 2017 Sep 28; 12(2). PMID: 28948509    Free PMC article.
In-vitro effect of pembrolizumab on different T regulatory cell subsets.
S M Toor, A S Syed Khaja, I Alkurd, E Elkord.
Clin Exp Immunol, 2017 Oct 01; 191(2). PMID: 28963773    Free PMC article.
A Case Report of Steroid Responsive Nivolumab-Induced Encephalitis.
Kaja Richard, Jacqueline Weslow, Stephanie L Porcella, Sowmya Nanjappa.
Cancer Control, 2017 Oct 05; 24(5). PMID: 28975824    Free PMC article.
Improving radiotherapy in cancer treatment: Promises and challenges.
Helen H W Chen, Macus Tien Kuo.
Oncotarget, 2017 Oct 06; 8(37). PMID: 28977985    Free PMC article.
Fractional Laser Releases Tumor-Associated Antigens in Poorly Immunogenic Tumor and Induces Systemic Immunity.
Masayoshi Kawakubo, Trevor J Cunningham, Shadmehr Demehri, Dieter Manstein.
Sci Rep, 2017 Oct 08; 7(1). PMID: 28986576    Free PMC article.
The diverse functions of the PD1 inhibitory pathway.
Arlene H Sharpe, Kristen E Pauken.
Nat Rev Immunol, 2017 Oct 11; 18(3). PMID: 28990585
Highly Cited. Review.
Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma.
Maria-Carmela Speranza, Carmela Passaro, +18 authors, Sean E Lawler.
Neuro Oncol, 2017 Oct 11; 20(2). PMID: 29016938    Free PMC article.
CD4 and CD8 T lymphocyte interplay in controlling tumor growth.
Dmitrij Ostroumov, Nora Fekete-Drimusz, +2 authors, Norman Woller.
Cell Mol Life Sci, 2017 Oct 17; 75(4). PMID: 29032503    Free PMC article.
T Cell-Derived CD70 Delivers an Immune Checkpoint Function in Inflammatory T Cell Responses.
Rachel E O'Neill, Wei Du, +6 authors, Xuefang Cao.
J Immunol, 2017 Oct 20; 199(10). PMID: 29046346    Free PMC article.
A herpesvirus entry mediator mutein with selective agonist action for the inhibitory receptor B and T lymphocyte attenuator.
John R Šedý, M Olivia Balmert, +6 authors, Carl F Ware.
J Biol Chem, 2017 Oct 25; 292(51). PMID: 29061848    Free PMC article.
An Archaeosome-Adjuvanted Vaccine and Checkpoint Inhibitor Therapy Combination Significantly Enhances Protection from Murine Melanoma.
Felicity C Stark, Risini D Weeratna, +4 authors, Lakshmi Krishnan.
Vaccines (Basel), 2017 Oct 27; 5(4). PMID: 29072624    Free PMC article.
Wandering pathways in the regulation of innate immunity and inflammation.
Alberto Mantovani.
J Autoimmun, 2017 Oct 29; 85. PMID: 29079064    Free PMC article.
Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma.
Keisuke Kataoka, Masako Iwanaga, +40 authors, Seishi Ogawa.
Blood, 2017 Nov 01; 131(2). PMID: 29084771    Free PMC article.
Vaccination in the immunotherapy of glioblastoma.
Ziren Kong, Yu Wang, Wenbin Ma.
Hum Vaccin Immunother, 2017 Nov 01; 14(2). PMID: 29087782    Free PMC article.
Cardiotoxicity of immune checkpoint inhibitors.
Gilda Varricchi, Maria Rosaria Galdiero, +5 authors, Carlo Gabriele Tocchetti.
ESMO Open, 2017 Nov 07; 2(4). PMID: 29104763    Free PMC article.
Highly Cited. Review.
Imaging the multiple facets of immuno-oncology.
Chaitanya Divgi.
Eur J Nucl Med Mol Imaging, 2017 Nov 10; 45(1). PMID: 29119236
Combining DNA damaging therapeutics with immunotherapy: more haste, less speed.
Jessica S Brown, Raghav Sundar, Juanita Lopez.
Br J Cancer, 2017 Nov 11; 118(3). PMID: 29123260    Free PMC article.
Highly Cited. Review.
PD-1 blockade at the time of tumor escape potentiates the immune-mediated antitumor effects of a melanoma-targeting monoclonal antibody.
Laetitia They, Henri-Alexandre Michaud, +8 authors, Laurent Gros.
Oncoimmunology, 2017 Nov 11; 6(10). PMID: 29123966    Free PMC article.
Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy.
David R Wilson, Rupashree Sen, +3 authors, Young J Kim.
Nanomedicine, 2017 Nov 12; 14(2). PMID: 29127039    Free PMC article.
Highly Cited.
An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression.
Asis Palazon, Petros A Tyrakis, +13 authors, Randall S Johnson.
Cancer Cell, 2017 Nov 15; 32(5). PMID: 29136509    Free PMC article.
Highly Cited.
Genetic and immune features of resectable malignant brainstem gliomas.
Yang Zhang, Changcun Pan, +4 authors, Liwei Zhang.
Oncotarget, 2017 Nov 16; 8(47). PMID: 29137285    Free PMC article.
Tumor-expressed immune checkpoint B7x promotes cancer progression and antigen-specific CD8 T cell exhaustion and suppressive innate immune cells.
Kim C Ohaegbulam, Weifeng Liu, +2 authors, Xingxing Zang.
Oncotarget, 2017 Nov 16; 8(47). PMID: 29137299    Free PMC article.
Immune checkpoint inhibitors: new strategies to checkmate cancer.
R A M Wilson, T R J Evans, A R Fraser, R J B Nibbs.
Clin Exp Immunol, 2017 Nov 16; 191(2). PMID: 29139554    Free PMC article.
Advanced smart-photosensitizers for more effective cancer treatment.
Wooram Park, Soojeong Cho, +4 authors, Dong-Hyun Kim.
Biomater Sci, 2017 Nov 17; 6(1). PMID: 29142997    Free PMC article.
EGFR mutation correlates with uninflamed phenotype and weak immunogenicity, causing impaired response to PD-1 blockade in non-small cell lung cancer.
Zhong-Yi Dong, Jia-Tao Zhang, +10 authors, Yi-Long Wu.
Oncoimmunology, 2017 Nov 18; 6(11). PMID: 29147605    Free PMC article.
Highly Cited.
Trial watch: Immune checkpoint blockers for cancer therapy.
Claire Vanpouille-Box, Claire Lhuillier, +10 authors, Lorenzo Galluzzi.
Oncoimmunology, 2017 Nov 18; 6(11). PMID: 29147629    Free PMC article.
Highly Cited. Review.
Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance.
Jinfang Zhang, Xia Bu, +15 authors, Wenyi Wei.
Nature, 2017 Nov 22; 553(7686). PMID: 29160310    Free PMC article.
Highly Cited.
Interleukin 6 Present in Inflammatory Ascites from Advanced Epithelial Ovarian Cancer Patients Promotes Tumor Necrosis Factor Receptor 2-Expressing Regulatory T Cells.
Nirmala Chandralega Kampan, Mutsa Tatenda Madondo, +3 authors, Magdalena Plebanski.
Front Immunol, 2017 Nov 23; 8. PMID: 29163543    Free PMC article.
Enhanced antitumor effects and improved immune status of dendritic cell and cytokine-induced killer cell infusion in advanced cancer patients.
Feng Chen, Menghan Yang, +9 authors, Jun Ren.
Mol Clin Oncol, 2017 Nov 29; 7(5). PMID: 29181186    Free PMC article.
Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth.
Giovanni Germano, Simona Lamba, +23 authors, Alberto Bardelli.
Nature, 2017 Dec 01; 552(7683). PMID: 29186113
Highly Cited.
Non-Canonical Thinking for Targeting ALK-Fusion Onco-Proteins in Lung Cancer.
Wei Wu, Franziska Haderk, Trever G Bivona.
Cancers (Basel), 2017 Dec 01; 9(12). PMID: 29189709    Free PMC article.
Next generation antibody drugs: pursuit of the 'high-hanging fruit'.
Paul J Carter, Greg A Lazar.
Nat Rev Drug Discov, 2017 Dec 02; 17(3). PMID: 29192287
Highly Cited. Review.
Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy.
Guizhi Zhu, Geoffrey M Lynn, +22 authors, Xiaoyuan Chen.
Nat Commun, 2017 Dec 06; 8(1). PMID: 29203865    Free PMC article.
Intracellular S100A9 Promotes Myeloid-Derived Suppressor Cells during Late Sepsis.
Jun Dai, Ajinkya Kumbhare, +2 authors, Mohamed El Gazzar.
Front Immunol, 2017 Dec 06; 8. PMID: 29204146    Free PMC article.
Trial Watch: Immunostimulatory monoclonal antibodies for oncological indications.
Mariona Cabo, Rienk Offringa, +3 authors, Lorenzo Galluzzi.
Oncoimmunology, 2017 Dec 07; 6(12). PMID: 29209572    Free PMC article.
Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics.
Abhishek D Garg, Sanket More, +6 authors, Lorenzo Galluzzi.
Oncoimmunology, 2017 Dec 07; 6(12). PMID: 29209573    Free PMC article.
Highly Cited. Review.
Trial watch: DNA-based vaccines for oncological indications.
Stefano Pierini, Renzo Perales-Linares, +5 authors, Lorenzo Galluzzi.
Oncoimmunology, 2017 Dec 07; 6(12). PMID: 29209575    Free PMC article.
Distinct mobilization of leukocytes and hematopoietic stem cells by CXCR4 peptide antagonist LY2510924 and monoclonal antibody LY2624587.
Sheng-Bin Peng, Robert D Van Horn, +7 authors, John R Stille.
Oncotarget, 2017 Dec 08; 8(55). PMID: 29212254    Free PMC article.
Molecular Biomarkers of Primary and Acquired Resistance to T-Cell-Mediated Immunotherapy in Cancer: Landscape, Clinical Implications, and Future Directions.
Young Kwang Chae, Michael S Oh, Francis J Giles.
Oncologist, 2017 Dec 16; 23(4). PMID: 29242279    Free PMC article.
Size, Shape, and Sequence-Dependent Immunogenicity of RNA Nanoparticles.
Sijin Guo, Hui Li, +3 authors, Peixuan Guo.
Mol Ther Nucleic Acids, 2017 Dec 17; 9. PMID: 29246318    Free PMC article.
PD-1/PD-L1 binding studies using microscale thermophoresis.
Romain Magnez, Bryan Thiroux, +3 authors, Xavier Thuru.
Sci Rep, 2017 Dec 17; 7(1). PMID: 29247197    Free PMC article.
Combination Immunotherapy of MUC1 mRNA Nano-vaccine and CTLA-4 Blockade Effectively Inhibits Growth of Triple Negative Breast Cancer.
Lina Liu, Yuhua Wang, +4 authors, Leaf Huang.
Mol Ther, 2017 Dec 21; 26(1). PMID: 29258739    Free PMC article.
Immune phenotypes of prostate cancer cells: Evidence of epithelial immune cell-like transition?
Dong Lin, Xinya Wang, +3 authors, Yuzhuo Wang.
Asian J Urol, 2016 Oct 01; 3(4). PMID: 29264187    Free PMC article.
Novel immunotherapy approaches for metastatic urothelial and renal cell carcinoma.
Zhiying Shao, Andrew Z Wang, Daniel J George, Tian Zhang.
Asian J Urol, 2016 Oct 01; 3(4). PMID: 29264195    Free PMC article.
The dawn of vaccines for cancer prevention.
Olivera J Finn.
Nat Rev Immunol, 2017 Dec 28; 18(3). PMID: 29279613
Highly Cited. Review.
Conditional Knockdown of Gene Expression in Cancer Cell Lines to Study the Recruitment of Monocytes/Macrophages to the Tumor Microenvironment.
Marta H Kubala, Yves A DeClerck.
J Vis Exp, 2017 Dec 30; (129). PMID: 29286360    Free PMC article.
Generating the Abscopal Effect by Combining Proapoptotic Peptides With IL-12-Based Immunotherapy.
Filipe Martins, Grégoire Stalder, Michel Obeid.
Neoplasia, 2017 Dec 30; 20(2). PMID: 29287248    Free PMC article.
A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors.
Yasuki Hijikata, Toshihiko Okazaki, +10 authors, Kenzaburo Tani.
PLoS One, 2018 Jan 03; 13(1). PMID: 29293510    Free PMC article.
TNFR2: The new Treg switch?
José L Cohen, Kathryn J Wood.
Oncoimmunology, 2018 Jan 04; 7(1). PMID: 29296530    Free PMC article.
Regulation of PD-1/PD-L1 pathway and resistance to PD-1/PD-L1 blockade.
Jie Bai, Zhitao Gao, +3 authors, Jing Nie.
Oncotarget, 2018 Jan 05; 8(66). PMID: 29299180    Free PMC article.
Perspectives in small cell lung cancer: is something moving?
Lucio Crinò, Angelo Delmonte.
Transl Lung Cancer Res, 2018 Jan 05; 6(Suppl 1). PMID: 29299410    Free PMC article.
Cancer immunotherapy in patients with new or recurrent malignancies after liver transplantation.
Mengqi Liu, Wenzhi Guo, Shuijun Zhang.
Int J Surg Oncol (N Y), 2018 Jan 06; 2(11). PMID: 29302641    Free PMC article.
PD-1 related transcriptome profile and clinical outcome in diffuse gliomas.
Shuai Liu, Zheng Wang, +5 authors, Tao Jiang.
Oncoimmunology, 2018 Jan 09; 7(2). PMID: 29308304    Free PMC article.
The T cell repertoire in tumors overlaps with pulmonary inflammatory lesions in patients treated with checkpoint inhibitors.
Heinz Läubli, Viktor H Koelzer, +6 authors, Alfred Zippelius.
Oncoimmunology, 2018 Jan 09; 7(2). PMID: 29308309    Free PMC article.
Hitting the Target: How T Cells Detect and Eliminate Tumors.
Anthony E Zamora, Jeremy Chase Crawford, Paul G Thomas.
J Immunol, 2018 Jan 10; 200(2). PMID: 29311380    Free PMC article.
Toll-Like Receptor 3 Signal in Dendritic Cells Benefits Cancer Immunotherapy.
Misako Matsumoto, Yohei Takeda, Megumi Tatematsu, Tsukasa Seya.
Front Immunol, 2018 Jan 10; 8. PMID: 29312355    Free PMC article.
The Role of Mass Spectrometry and Proteogenomics in the Advancement of HLA Epitope Prediction.
Amanda L Creech, Ying S Ting, +5 authors, Jennifer G Abelin.
Proteomics, 2018 Jan 10; 18(12). PMID: 29314742    Free PMC article.
Precision oncology in the age of integrative genomics.
Chandan Kumar-Sinha, Arul M Chinnaiyan.
Nat Biotechnol, 2018 Jan 11; 36(1). PMID: 29319699    Free PMC article.
Evolving notions on immune response in colorectal cancer and their implications for biomarker development.
Fabio Grizzi, Gianluca Basso, +6 authors, Luigi Laghi.
Inflamm Res, 2018 Jan 13; 67(5). PMID: 29322204
A novel biologic platform elicits profound T cell costimulatory activity and antitumor immunity in mice.
Joseph M Ryan, Payal Mittal, +4 authors, Anthony T Vella.
Cancer Immunol Immunother, 2018 Jan 13; 67(4). PMID: 29327109    Free PMC article.
Cancer immunotherapy beyond immune checkpoint inhibitors.
Julian A Marin-Acevedo, Aixa E Soyano, +2 authors, Yanyan Lou.
J Hematol Oncol, 2018 Jan 14; 11(1). PMID: 29329556    Free PMC article.
Highly Cited. Review.
Recent advances in the biology and therapy of medullary thyroid carcinoma.
Barry Nelkin.
F1000Res, 2018 Jan 16; 6. PMID: 29333262    Free PMC article.
Dinaciclib induces immunogenic cell death and enhances anti-PD1-mediated tumor suppression.
Dewan Md Sakib Hossain, Sarah Javaid, +8 authors, Alissa Chackerian.
J Clin Invest, 2018 Jan 18; 128(2). PMID: 29337311    Free PMC article.
Repurposing Tin Mesoporphyrin as an Immune Checkpoint Inhibitor Shows Therapeutic Efficacy in Preclinical Models of Cancer.
Tamara Muliaditan, James W Opzoomer, +14 authors, James N Arnold.
Clin Cancer Res, 2018 Jan 18; 24(7). PMID: 29339440    Free PMC article.
Programmed death-ligand 1 is a promising blood marker for predicting tumor progression and prognosis in patients with gastric cancer.
Masahiko Amatatsu, Takaaki Arigami, +11 authors, Shoji Natsugoe.
Cancer Sci, 2018 Jan 19; 109(3). PMID: 29345842    Free PMC article.
Increased diversity with reduced "diversity evenness" of tumor infiltrating T-cells for the successful cancer immunotherapy.
Akihiro Hosoi, Kazuyoshi Takeda, +10 authors, Kazuhiro Kakimi.
Sci Rep, 2018 Jan 20; 8(1). PMID: 29348598    Free PMC article.
Unwrapping the genomic characteristics of urothelial bladder cancer and successes with immune checkpoint blockade therapy.
Wen Cheng, Dian Fu, Feng Xu, Zhengyu Zhang.
Oncogenesis, 2018 Jan 24; 7(1). PMID: 29358573    Free PMC article.
A kinetic investigation of interacting, stimulated T cells identifies conditions for rapid functional enhancement, minimal phenotype differentiation, and improved adoptive cell transfer tumor eradication.
Jing Zhou, Michael T Bethune, +6 authors, James R Heath.
PLoS One, 2018 Jan 24; 13(1). PMID: 29360859    Free PMC article.
Tackling Cancer Resistance by Immunotherapy: Updated Clinical Impact and Safety of PD-1/PD-L1 Inhibitors.
Shifaa M Abdin, Dana M Zaher, El-Shaimaa A Arafa, Hany A Omar.
Cancers (Basel), 2018 Jan 26; 10(2). PMID: 29370105    Free PMC article.
The structure, expression, and multifaceted role of immune-checkpoint protein VISTA as a critical regulator of anti-tumor immunity, autoimmunity, and inflammation.
Wenwen Xu, TạMinh Hiếu, Subramaniam Malarkannan, Li Wang.
Cell Mol Immunol, 2018 Jan 30; 15(5). PMID: 29375120    Free PMC article.
IDO1 in cancer: a Gemini of immune checkpoints.
Lijie Zhai, Erik Ladomersky, +5 authors, Derek A Wainwright.
Cell Mol Immunol, 2018 Jan 30; 15(5). PMID: 29375124    Free PMC article.
Highly Cited. Review.
A Comprehensive Review of US FDA-Approved Immune Checkpoint Inhibitors in Urothelial Carcinoma.
Fu-Shun Hsu, Chun-Hung Su, Kou-How Huang.
J Immunol Res, 2018 Jan 30; 2017. PMID: 29376081    Free PMC article.
AIMp1 Potentiates TH1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity.
Dan Liang, Lin Tian, +14 authors, William K Decker.
Front Immunol, 2018 Jan 31; 8. PMID: 29379495    Free PMC article.
Inhibition of the checkpoint protein PD-1 by the therapeutic antibody pembrolizumab outlined by quantum chemistry.
Ana Beatriz M L A Tavares, José X Lima Neto, Umberto L Fulco, Eudenilson L Albuquerque.
Sci Rep, 2018 Feb 01; 8(1). PMID: 29382901    Free PMC article.
Interferon gamma, an important marker of response to immune checkpoint blockade in non-small cell lung cancer and melanoma patients.
Niki Karachaliou, Maria Gonzalez-Cao, +15 authors, Rafael Rosell.
Ther Adv Med Oncol, 2018 Feb 01; 10. PMID: 29383037    Free PMC article.
Highly Cited.
Combined immunotherapy for advanced prostate cancer: Empowering the T cell army.
Sufyan Suleman, Gong-Hong Wei.
Asian J Urol, 2018 Feb 02; 4(4). PMID: 29387551    Free PMC article.
The tumour glyco-code as a novel immune checkpoint for immunotherapy.
Ernesto RodrÍguez, Sjoerd T T Schetters, Yvette van Kooyk.
Nat Rev Immunol, 2018 Feb 06; 18(3). PMID: 29398707
Highly Cited. Review.
Dendritic cell vaccine induces antigen-specific CD8+ T cells that are metabolically distinct from those of peptide vaccine and is well-combined with PD-1 checkpoint blockade.
Koji Nagaoka, Akihiro Hosoi, +3 authors, Kazuhiro Kakimi.
Oncoimmunology, 2018 Feb 06; 7(3). PMID: 29399391    Free PMC article.
Recent Advances in Targeting CD8 T-Cell Immunity for More Effective Cancer Immunotherapy.
Aurélie Durgeau, Yasemin Virk, Stéphanie Corgnac, Fathia Mami-Chouaib.
Front Immunol, 2018 Feb 07; 9. PMID: 29403496    Free PMC article.
Highly Cited. Review.
A Comprehensive Immunologic Portrait of Triple-Negative Breast Cancer.
Zhixian Liu, Mengyuan Li, Zehang Jiang, Xiaosheng Wang.
Transl Oncol, 2018 Feb 08; 11(2). PMID: 29413765    Free PMC article.
Highly Cited.
Polymicrobial sepsis and non-specific immunization induce adaptive immunosuppression to a similar degree.
Katrin Schmoeckel, Daniel M Mrochen, +2 authors, Barbara M Bröker.
PLoS One, 2018 Feb 08; 13(2). PMID: 29415028    Free PMC article.
Antibody targeting of phosphatidylserine for the detection and immunotherapy of cancer.
Olivier Belzile, Xianming Huang, +4 authors, Bruce D Freimark.
Immunotargets Ther, 2018 Feb 09; 7. PMID: 29417044    Free PMC article.
The efficacy and safety of anti-PD-1/PD-L1 antibody therapy versus docetaxel for pretreated advanced NSCLC: a meta-analysis.
Guanghong Huang, Xin Sun, +9 authors, Sida Qin.
Oncotarget, 2018 Feb 10; 9(3). PMID: 29423118    Free PMC article.
Potentiating prostate cancer immunotherapy with oncolytic viruses.
Patrick Lee, Shashi Gujar.
Nat Rev Urol, 2018 Feb 13; 15(4). PMID: 29434366
High expression of carcinoembryonic antigen and telomerase reverse transcriptase in circulating tumor cells is associated with poor clinical response to the immune checkpoint inhibitor nivolumab.
Halin Bao, Tuya Bai, +23 authors, Kyoichi Kaira.
Oncol Lett, 2018 Feb 13; 15(3). PMID: 29435038    Free PMC article.
Neuroinflammation and Central Sensitization in Chronic and Widespread Pain.
Ru-Rong Ji, Andrea Nackley, +2 authors, William Maixner.
Anesthesiology, 2018 Feb 21; 129(2). PMID: 29462012    Free PMC article.
Highly Cited. Review.
Abnormal expression of circulating and tumor-infiltrating carcinoembryonic antigen-related cell adhesion molecule 1 in patients with glioma.
Jinhu Li, Xiaodong Liu, +5 authors, Yimin Fan.
Oncol Lett, 2018 Feb 23; 15(3). PMID: 29467871    Free PMC article.
Non-Invasive Radiofrequency Field Treatment of 4T1 Breast Tumors Induces T-cell Dependent Inflammatory Response.
Jared M Newton, Jose H Flores-Arredondo, +7 authors, Stuart J Corr.
Sci Rep, 2018 Feb 24; 8(1). PMID: 29472563    Free PMC article.
Systemic immune-inflammation index in germ-cell tumours.
Michal Chovanec, Zuzana Cierna, +11 authors, Jozef Mardiak.
Br J Cancer, 2018 Feb 28; 118(6). PMID: 29485980    Free PMC article.
Loss of Rictor in Monocyte/Macrophages Suppresses Their Proliferation and Viability Reducing Atherosclerosis in LDLR Null Mice.
Vladimir R Babaev, Jiansheng Huang, +3 authors, MacRae F Linton.
Front Immunol, 2018 Mar 01; 9. PMID: 29487597    Free PMC article.
Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression.
Yanxia Guo, Alice M Walsh, +18 authors, Sunil Nagpal.
PLoS One, 2018 Mar 01; 13(2). PMID: 29489833    Free PMC article.
Highly Cited.
Immune Monitoring of Cancer Patients Prior to and During CTLA-4 or PD-1/PD-L1 Inhibitor Treatment.
Antje Tunger, Maximilian Kießler, +4 authors, Marc Schmitz.
Biomedicines, 2018 Mar 02; 6(1). PMID: 29494517    Free PMC article.
Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered FcγReceptor IIIa-Immobilized Column.
Masato Kiyoshi, Jose M M Caaveiro, +13 authors, Akiko Ishii-Watabe.
Sci Rep, 2018 Mar 04; 8(1). PMID: 29500371    Free PMC article.
Genetic Mechanisms of Immune Evasion in Colorectal Cancer.
Catherine S Grasso, Marios Giannakis, +49 authors, Ulrike Peters.
Cancer Discov, 2018 Mar 08; 8(6). PMID: 29510987    Free PMC article.
Highly Cited.
Genotypic and phenotypic signatures to predict immune checkpoint blockade therapy response in patients with colorectal cancer.
Xianda Zhao, Audre May, Emil Lou, Subbaya Subramanian.
Transl Res, 2018 Mar 09; 196. PMID: 29518351    Free PMC article.
PTEN at the interface of immune tolerance and tumor suppression.
Andrew Brandmaier, Sheng-Qi Hou, +2 authors, Wen H Shen.
Front Biol (Beijing), 2018 Mar 13; 12(3). PMID: 29527223    Free PMC article.
Targeting DNA damage repair in small cell lung cancer and the biomarker landscape.
Triparna Sen, Carl M Gay, Lauren Averett Byers.
Transl Lung Cancer Res, 2018 Mar 15; 7(1). PMID: 29535912    Free PMC article.
Next generation of immune checkpoint therapy in cancer: new developments and challenges.
Julian A Marin-Acevedo, Bhagirathbhai Dholaria, +3 authors, Yanyan Lou.
J Hematol Oncol, 2018 Mar 17; 11(1). PMID: 29544515    Free PMC article.
Highly Cited. Review.
γδ T cell-mediated individualized immunotherapy for hepatocellular carcinoma considering clinicopathological characteristics and immunosuppressive factors.
Wei Tian, Jun Ma, +3 authors, Haoliang Zhao.
Oncol Lett, 2018 Mar 20; 15(4). PMID: 29552184    Free PMC article.
Cancer vaccines: translation from mice to human clinical trials.
Hoyoung Maeng, Masaki Terabe, Jay A Berzofsky.
Curr Opin Immunol, 2018 Mar 20; 51. PMID: 29554495    Free PMC article.
Blocking IFNAR1 inhibits multiple myeloma-driven Treg expansion and immunosuppression.
Yawara Kawano, Oksana Zavidij, +24 authors, Irene M Ghobrial.
J Clin Invest, 2018 Mar 21; 128(6). PMID: 29558366    Free PMC article.
Characterizing the Role of Monocytes in T Cell Cancer Immunotherapy Using a 3D Microfluidic Model.
Sharon Wei Ling Lee, Giulia Adriani, +5 authors, Siew Cheng Wong.
Front Immunol, 2018 Mar 22; 9. PMID: 29559973    Free PMC article.
Exhaustion of the CD8+ T Cell Compartment in Patients with Mutations in Phosphoinositide 3-Kinase Delta.
Marjolein W J Wentink, Yvonne M Mueller, +5 authors, Peter D Katsikis.
Front Immunol, 2018 Mar 23; 9. PMID: 29563914    Free PMC article.
Immunotherapy for Merkel cell carcinoma: a turning point in patient care.
Isaac S Chan, Shailender Bhatia, Howard L Kaufman, Evan J Lipson.
J Immunother Cancer, 2018 Mar 24; 6(1). PMID: 29566749    Free PMC article.
Current Strategies to Enhance Anti-Tumour Immunity.
Katherine W Cook, Lindy G Durrant, Victoria A Brentville.
Biomedicines, 2018 Mar 24; 6(2). PMID: 29570634    Free PMC article.
Anti-CTLA-4 therapy requires an Fc domain for efficacy.
Jessica R Ingram, Olga S Blomberg, +15 authors, Michael Dougan.
Proc Natl Acad Sci U S A, 2018 Mar 28; 115(15). PMID: 29581255    Free PMC article.
Highly Cited.
Harnessing and Optimizing the Interplay between Immunotherapy and Radiotherapy to Improve Survival Outcomes.
Kalpana Mujoo, Clayton R Hunt, +5 authors, Tej K Pandita.
Mol Cancer Res, 2018 Mar 30; 16(8). PMID: 29592896    Free PMC article.
Overexpression of HHLA2, a member of the B7 family, is associated with worse survival in human colorectal carcinoma.
Ziwen Zhu, Weiguo Dong.
Onco Targets Ther, 2018 Mar 30; 11. PMID: 29593422    Free PMC article.
Tumor Necrosis Factor α and Regulatory T Cells in Oncoimmunology.
Benoît L Salomon, Mathieu Leclerc, +3 authors, José L Cohen.
Front Immunol, 2018 Mar 30; 9. PMID: 29593717    Free PMC article.
CMTM6 stabilizes PD-L1 expression and refines its prognostic value in tumors.
Emilie Mamessier, David J Birnbaum, +2 authors, François Bertucci.
Ann Transl Med, 2018 Apr 04; 6(3). PMID: 29610746    Free PMC article.
Novel bone morphogenetic protein receptor inhibitor JL5 suppresses tumor cell survival signaling and induces regression of human lung cancer.
Jenna H Newman, David J Augeri, +18 authors, John Langenfeld.
Oncogene, 2018 Apr 07; 37(27). PMID: 29622797
Combination Immunotherapy: Taking Cancer Vaccines to the Next Level.
Jeremy M Grenier, Stephen T Yeung, Kamal M Khanna.
Front Immunol, 2018 Apr 07; 9. PMID: 29623082    Free PMC article.
CD8+ T Cells and NK Cells: Parallel and Complementary Soldiers of Immunotherapy.
Jillian Rosenberg, Jun Huang.
Curr Opin Chem Eng, 2018 Apr 07; 19. PMID: 29623254    Free PMC article.
CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT.
Muhammad Zaeem Noman, Kris Van Moer, +8 authors, Bassam Janji.
Oncoimmunology, 2018 Apr 11; 7(4). PMID: 29632713    Free PMC article.
Tailoring CD19xCD3-DART exposure enhances T-cells to eradication of B-cell neoplasms.
Paola Circosta, Angela Rita Elia, +22 authors, Giorgio Inghirami.
Oncoimmunology, 2018 Apr 11; 7(4). PMID: 29632712    Free PMC article.
The immunocytokine L19-IL2: An interplay between radiotherapy and long-lasting systemic anti-tumour immune responses.
Nicolle H Rekers, Veronica Olivo Pimentel, +8 authors, Philippe Lambin.
Oncoimmunology, 2018 Apr 11; 7(4). PMID: 29632732    Free PMC article.
The Immune Revolution: A Case for Priming, Not Checkpoint.
Robert H Vonderheide.
Cancer Cell, 2018 Apr 11; 33(4). PMID: 29634944    Free PMC article.
Highly Cited. Review.
Molecular Signatures of Regression of the Canine Transmissible Venereal Tumor.
Dan Frampton, Hagen Schwenzer, +12 authors, Ariberto Fassati.
Cancer Cell, 2018 Apr 11; 33(4). PMID: 29634949    Free PMC article.
The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy.
Yeon-Soo Seo, Young-Hoon Kang.
Front Mol Biosci, 2018 Apr 14; 5. PMID: 29651420    Free PMC article.
Strategy to targeting the immune resistance and novel therapy in colorectal cancer.
Wang Gang, Jun-Jie Wang, +6 authors, Xing-Li Fu.
Cancer Med, 2018 Apr 17; 7(5). PMID: 29658188    Free PMC article.
Combination Cancer Immunotherapy in Hepatocellular Carcinoma.
Masatoshi Kudo.
Liver Cancer, 2018 Apr 18; 7(1). PMID: 29662830    Free PMC article.
Increased vessel perfusion predicts the efficacy of immune checkpoint blockade.
Xichen Zheng, Zhaoxu Fang, +17 authors, Yuhui Huang.
J Clin Invest, 2018 Apr 18; 128(5). PMID: 29664018    Free PMC article.
Discovery of Novel Indoleamine 2,3-Dioxygenase 1 (IDO1) and Histone Deacetylase (HDAC) Dual Inhibitors.
Kun Fang, Guoqiang Dong, +5 authors, Chunquan Sheng.
ACS Med Chem Lett, 2018 Apr 20; 9(4). PMID: 29670692    Free PMC article.
Activation of Human Natural Killer Cells by Graphene Oxide-Templated Antibody Nanoclusters.
Christian Loftus, Mezida Saeed, Daniel M Davis, Iain E Dunlop.
Nano Lett, 2018 Apr 21; 18(5). PMID: 29676151    Free PMC article.
A Dual Immunotherapy Nanoparticle Improves T-Cell Activation and Cancer Immunotherapy.
Yu Mi, Christof C Smith, +5 authors, Andrew Z Wang.
Adv Mater, 2018 Apr 25; 30(25). PMID: 29691900    Free PMC article.
Combination Immunotherapy Approaches for Pancreatic Cancer Treatment.
Xianliang Cheng, Gang Zhao, Yunqi Zhao.
Can J Gastroenterol Hepatol, 2018 May 01; 2018. PMID: 29707526    Free PMC article.
PD-L1 expression in medulloblastoma: an evaluation by subgroup.
Allison M Martin, Christopher J Nirschl, +19 authors, Michael Lim.
Oncotarget, 2018 May 04; 9(27). PMID: 29721192    Free PMC article.
Animal models for studying tumor microenvironment (TME) and resistance to lymphocytic infiltration.
Ryuji Yamaguchi, Guy Perkins.
Cancer Biol Ther, 2018 May 04; 19(9). PMID: 29723108    Free PMC article.
Lighting a Fire in the Tumor Microenvironment Using Oncolytic Immunotherapy.
Carole Achard, Abera Surendran, +3 authors, Carolina S Ilkow.
EBioMedicine, 2018 May 05; 31. PMID: 29724655    Free PMC article.
Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism.
Tian Du, Li Zhu, +6 authors, Steffi Oesterreich.
Sci Rep, 2018 May 10; 8(1). PMID: 29739984    Free PMC article.
Emergence of immunotherapy as a novel way to treat hepatocellular carcinoma.
Naofumi Mukaida, Yasunari Nakamoto.
World J Gastroenterol, 2018 May 10; 24(17). PMID: 29740200    Free PMC article.
A gene profiling deconvolution approach to estimating immune cell composition from complex tissues.
Shu-Hwa Chen, Wen-Yu Kuo, +4 authors, Chung-Yen Lin.
BMC Bioinformatics, 2018 May 11; 19(Suppl 4). PMID: 29745829    Free PMC article.
A New Strategy to Control and Eradicate "Undruggable" Oncogenic K-RAS-Driven Pancreatic Cancer: Molecular Insights and Core Principles Learned from Developmental and Evolutionary Biology.
Robert E Van Sciver, Michael P Lee, +13 authors, Amy H Tang.
Cancers (Basel), 2018 May 15; 10(5). PMID: 29757973    Free PMC article.
Risk of immune-related colitis with PD-1/PD-L1 inhibitors vs chemotherapy in solid tumors: systems assessment.
Qiang Su, Xiaochen Zhang, +3 authors, Zu Hua Gao.
J Cancer, 2018 May 16; 9(9). PMID: 29760800    Free PMC article.
STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion.
Jung-Mao Hsu, Weiya Xia, +14 authors, Mien-Chie Hung.
Nat Commun, 2018 May 17; 9(1). PMID: 29765039    Free PMC article.
Highly Cited.
Genetic, transcriptional and post-translational regulation of the programmed death protein ligand 1 in cancer: biology and clinical correlations.
Ioannis Zerdes, Alexios Matikas, +2 authors, Theodoros Foukakis.
Oncogene, 2018 May 17; 37(34). PMID: 29765155    Free PMC article.
Highly Cited. Review.
Long-Term Persistence of Exhausted CD8 T Cells in Chronic Infection Is Regulated by MicroRNA-155.
Erietta Stelekati, Zeyu Chen, +10 authors, E John Wherry.
Cell Rep, 2018 May 17; 23(7). PMID: 29768211    Free PMC article.
B4GALT1 expression predicts prognosis and adjuvant chemotherapy benefits in muscle-invasive bladder cancer patients.
Huyang Xie, Yu Zhu, +8 authors, Dingwei Ye.
BMC Cancer, 2018 May 26; 18(1). PMID: 29793447    Free PMC article.
Keeping Tumors in Check: A Mechanistic Review of Clinical Response and Resistance to Immune Checkpoint Blockade in Cancer.
Nicholas Borcherding, Ryan Kolb, +3 authors, Weizhou Zhang.
J Mol Biol, 2018 May 26; 430(14). PMID: 29800567    Free PMC article.
Toward Small-Molecule Inhibition of Protein-Protein Interactions: General Aspects and Recent Progress in Targeting Costimulatory and Coinhibitory (Immune Checkpoint) Interactions.
Damir Bojadzic, Peter Buchwald.
Curr Top Med Chem, 2018 Jun 01; 18(8). PMID: 29848279    Free PMC article.
Tune Up In Situ Autovaccination against Solid Tumors with Oncolytic Viruses.
Teresa Nguyen, Naze G Avci, +2 authors, Hong Jiang.
Cancers (Basel), 2018 Jun 03; 10(6). PMID: 29857493    Free PMC article.
Advanced small cell lung cancer (SCLC): new challenges and new expectations.
Nikolaos Tsoukalas, Eleni Aravantinou-Fatorou, +5 authors, George Kyrgias.
Ann Transl Med, 2018 Jun 05; 6(8). PMID: 29862234    Free PMC article.
"Immune TOR-opathies," a Novel Disease Entity in Clinical Immunology.
Sophie Jung, Laura Gámez-Díaz, Michele Proietti, Bodo Grimbacher.
Front Immunol, 2018 Jun 06; 9. PMID: 29867948    Free PMC article.
C-C motif chemokine 22 predicts postoperative prognosis and adjuvant chemotherapeutic benefits in patients with stage II/III gastric cancer.
Songyang Wu, Hongyong He, +7 authors, Jiejie Xu.
Oncoimmunology, 2018 Jun 07; 7(6). PMID: 29872564    Free PMC article.
Trial Watch: Immunostimulation with recombinant cytokines for cancer therapy.
Elena García-Martínez, Melody Smith, +10 authors, Lorenzo Galluzzi.
Oncoimmunology, 2018 Jun 07; 7(6). PMID: 29872569    Free PMC article.
The design of high affinity human PD-1 mutants by using molecular dynamics simulations (MD).
Jiangfeng Du, Yaping Qin, +5 authors, Yanfeng Gao.
Cell Commun Signal, 2018 Jun 09; 16(1). PMID: 29879980    Free PMC article.
Antitumor Immunity Is Controlled by Tetraspanin Proteins.
Fleur Schaper, Annemiek B van Spriel.
Front Immunol, 2018 Jun 14; 9. PMID: 29896201    Free PMC article.
Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy.
Kaiyuan Ni, Guangxu Lan, +7 authors, Wenbin Lin.
Nat Commun, 2018 Jun 17; 9(1). PMID: 29907739    Free PMC article.
Oncolytic Reovirus and Immune Checkpoint Inhibition as a Novel Immunotherapeutic Strategy for Breast Cancer.
Ahmed A Mostafa, Daniel E Meyers, +6 authors, Don G Morris.
Cancers (Basel), 2018 Jun 20; 10(6). PMID: 29914097    Free PMC article.
Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses.
Fokhrul Hossain, Samarpan Majumder, +5 authors, Lucio Miele.
Front Immunol, 2018 Jun 20; 9. PMID: 29915603    Free PMC article.
STAT3 in Tumor-Associated Myeloid Cells: Multitasking to Disrupt Immunity.
Yu-Lin Su, Shuvomoy Banerjee, Seok Voon White, Marcin Kortylewski.
Int J Mol Sci, 2018 Jun 21; 19(6). PMID: 29921770    Free PMC article.
Expression patterns of programmed death ligand 1 correlate with different microenvironments and patient prognosis in hepatocellular carcinoma.
Chao-Qun Liu, Jing Xu, +7 authors, Limin Zheng.
Br J Cancer, 2018 Jun 21; 119(1). PMID: 29921949    Free PMC article.
Melanoma treatment in review.
Beatriz Domingues, José Manuel Lopes, Paula Soares, Helena Pópulo.
Immunotargets Ther, 2018 Jun 21; 7. PMID: 29922629    Free PMC article.
Highly Cited. Review.
Construction of an anti-programmed death-ligand 1 chimeric antigen receptor and determination of its antitumor function with transduced cells.
Jiasen Xie, Zishan Zhou, Shunchang Jiao, Xiaokun Li.
Oncol Lett, 2018 Jun 22; 16(1). PMID: 29928397    Free PMC article.
Key questions about the checkpoint blockade-are microRNAs an answer?
Mihnea Dragomir, Baoqing Chen, Xiao Fu, George A Calin.
Cancer Biol Med, 2018 Jun 29; 15(2). PMID: 29951335    Free PMC article.
CD8+ T-Cell Density Imaging with 64Cu-Labeled Cys-Diabody Informs Immunotherapy Protocols.
Jai Woong Seo, Richard Tavaré, +7 authors, Katherine W Ferrara.
Clin Cancer Res, 2018 Jul 04; 24(20). PMID: 29967252    Free PMC article.
Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression.
Wei Xiang, Rongchen Shi, +20 authors, Hongming Miao.
Nat Commun, 2018 Jul 04; 9(1). PMID: 29968710    Free PMC article.
PD-L1 Nanobody Competitively Inhibits the Formation of the PD-1/PD-L1 Complex: Comparative Molecular Dynamics Simulations.
Xin Sun, Xiao Yan, +10 authors, Jianping Hu.
Int J Mol Sci, 2018 Jul 11; 19(7). PMID: 29986511    Free PMC article.
Immune Checkpoints as the Immune System Regulators and Potential Biomarkers in HIV-1 Infection.
Maike Sperk, Robert van Domselaar, Ujjwal Neogi.
Int J Mol Sci, 2018 Jul 11; 19(7). PMID: 29987244    Free PMC article.
Metronomics: Intrinsic Anakoinosis Modulator?
André Nicolas, Manon Carré, Eddy Pasquier.
Front Pharmacol, 2018 Jul 11; 9. PMID: 29988614    Free PMC article.
Cancer immune checkpoint blockade therapy and its associated autoimmune cardiotoxicity.
Jiu-Cheng Zhang, Wei-Dong Chen, +6 authors, Hua Zhu.
Acta Pharmacol Sin, 2018 Jul 12; 39(11). PMID: 29991709    Free PMC article.
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.
Jia-Ren Lin, Benjamin Izar, +5 authors, Peter K Sorger.
Elife, 2018 Jul 12; 7. PMID: 29993362    Free PMC article.
Highly Cited.
Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells.
Yunlong Zhao, Devin L Harrison, +3 authors, Enfu Hui.
Cell Rep, 2018 Jul 12; 24(2). PMID: 29996099    Free PMC article.
Tumor Dendritic Cells (DCs) Derived from Precursors of Conventional DCs Are Dispensable for Intratumor CTL Responses.
Jun Diao, Hongtao Gu, +2 authors, Mark S Cattral.
J Immunol, 2018 Jul 13; 201(4). PMID: 29997124    Free PMC article.
Novel tumour antigens and the development of optimal vaccine design.
Victoria A Brentville, Suha Atabani, Katherine Cook, Lindy G Durrant.
Ther Adv Vaccines Immunother, 2018 Jul 13; 6(2). PMID: 29998219    Free PMC article.
Current status of immunotherapy against gastrointestinal cancers and its biomarkers: Perspective for precision immunotherapy.
Shoichi Hazama, Koji Tamada, +2 authors, Hiroaki Nagano.
Ann Gastroenterol Surg, 2018 Jul 14; 2(4). PMID: 30003192    Free PMC article.
Oncolytic herpes simplex virus immunovirotherapy in combination with immune checkpoint blockade to treat glioblastoma.
Dipongkor Saha, Robert L Martuza, Samuel D Rabkin.
Immunotherapy, 2018 Jul 17; 10(9). PMID: 30008259    Free PMC article.
CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade.
Limo Chen, Lixia Diao, +36 authors, Don L Gibbons.
Cancer Discov, 2018 Jul 18; 8(9). PMID: 30012853    Free PMC article.
Highly Cited.
Safety and efficacy of durvalumab (MEDI4736) in various solid tumors.
Hui Yang, Kai Shen, +3 authors, Xuelei Ma.
Drug Des Devel Ther, 2018 Jul 18; 12. PMID: 30013326    Free PMC article.
Which criteria should we use to evaluate the efficacy of immune-checkpoint inhibitors?
Yuki Kataoka, Katsuya Hirano.
Ann Transl Med, 2018 Jul 20; 6(11). PMID: 30023385    Free PMC article.
Noninvasive imaging of the PD-1:PD-L1 immune checkpoint: Embracing nuclear medicine for the benefit of personalized immunotherapy.
Katrijn Broos, Quentin Lecocq, +3 authors, Karine Breckpot.
Theranostics, 2018 Jul 22; 8(13). PMID: 30026866    Free PMC article.
Diacylglycerol kinase ζ (DGKζ) and Casitas b-lineage proto-oncogene b-deficient mice have similar functional outcomes in T cells but DGKζ-deficient mice have increased T cell activation and tumor clearance.
Erin M Wesley, Gang Xin, +6 authors, Matthew J Riese.
Immunohorizons, 2018 Jul 22; 2(4). PMID: 30027154    Free PMC article.
Osteoglycin-induced VEGF Inhibition Enhances T Lymphocytes Infiltrating in Colorectal Cancer.
Xiang Hu, Ya-Qi Li, +3 authors, San-Jun Cai.
EBioMedicine, 2018 Jul 25; 34. PMID: 30037719    Free PMC article.
The role of proteomics in the age of immunotherapies.
Sarah A Hayes, Stephen Clarke, Nick Pavlakis, Viive M Howell.
Mamm Genome, 2018 Jul 27; 29(11-12). PMID: 30046851
Editorial: Local Immunotherapy: A Way to Convert Tumors From "Cold" to "Hot".
Marijo Bilusic, James L Gulley.
J Natl Cancer Inst, 2018 Jul 28; 109(12). PMID: 30053078    Free PMC article.
Notch Signaling as a Regulator of the Tumor Immune Response: To Target or Not To Target?
Mahnaz Janghorban, Li Xin, Jeffrey M Rosen, Xiang H-F Zhang.
Front Immunol, 2018 Aug 01; 9. PMID: 30061899    Free PMC article.
RTN4 Knockdown Dysregulates the AKT Pathway, Destabilizes the Cytoskeleton, and Enhances Paclitaxel-Induced Cytotoxicity in Cancers.
Gopal P Pathak, Rashmi Shah, +7 authors, Shashi Gujar.
Mol Ther, 2018 Aug 07; 26(8). PMID: 30078441    Free PMC article.
White paper on microbial anti-cancer therapy and prevention.
Neil S Forbes, Robert S Coffin, +20 authors, Grant McFadden.
J Immunother Cancer, 2018 Aug 08; 6(1). PMID: 30081947    Free PMC article.
Next Generation Cancer Vaccines-Make It Personal!
Angelika Terbuch, Juanita Lopez.
Vaccines (Basel), 2018 Aug 12; 6(3). PMID: 30096953    Free PMC article.
Going (Reo)Viral: Factors Promoting Successful Reoviral Oncolytic Infection.
Tarryn Bourhill, Yoshinori Mori, +2 authors, Randal N Johnston.
Viruses, 2018 Aug 15; 10(8). PMID: 30103501    Free PMC article.
PD-L1 Expression Correlates With Tumor Infiltrating Lymphocytes And Response To Neoadjuvant Chemotherapy In Cervical Cancer.
Ying Meng, Huyi Liang, +5 authors, Lina Hu.
J Cancer, 2018 Aug 21; 9(16). PMID: 30123362    Free PMC article.
Aptamer-based targeted therapy.
Guizhi Zhu, Xiaoyuan Chen.
Adv Drug Deliv Rev, 2018 Aug 21; 134. PMID: 30125604    Free PMC article.
Osteoglycin - A switch from angiogenesis to T-cell recruitment?
Anna Dimberg.
EBioMedicine, 2018 Aug 22; 35. PMID: 30126821    Free PMC article.
Lack of Sprouty 1 and 2 enhances survival of effector CD8+ T cells and yields more protective memory cells.
Hesham M Shehata, Shahzada Khan, +3 authors, Shomyseh Sanjabi.
Proc Natl Acad Sci U S A, 2018 Aug 22; 115(38). PMID: 30126987    Free PMC article.
Endogenous glucocorticoids control host resistance to viral infection through the tissue-specific regulation of PD-1 expression on NK cells.
Linda Quatrini, Elisabeth Wieduwild, +5 authors, Sophie Ugolini.
Nat Immunol, 2018 Aug 22; 19(9). PMID: 30127438    Free PMC article.
Highly Cited.
The Role of Toll-Like Receptor in Inflammation and Tumor Immunity.
Xiaohong Cen, Shuwen Liu, Kui Cheng.
Front Pharmacol, 2018 Aug 22; 9. PMID: 30127747    Free PMC article.
Highly Cited. Review.
Oncostatin M treatment increases the responsiveness toward cisplatin-based chemoradiotherapy in cervical cancer cells in a STAT3-dependent manner.
Russalina Stroeder, Barbara Walch-Rückheim, +4 authors, Sigrun Smola.
Oncol Lett, 2018 Aug 22; 16(3). PMID: 30127934    Free PMC article.
Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells.
Michal A Stanczak, Shoib S Siddiqui, +19 authors, Heinz Läubli.
J Clin Invest, 2018 Aug 22; 128(11). PMID: 30130255    Free PMC article.
CMTM6 overexpression is associated with molecular and clinical characteristics of malignancy and predicts poor prognosis in gliomas.
Xiudong Guan, Chuanbao Zhang, +3 authors, Wang Jia.
EBioMedicine, 2018 Aug 23; 35. PMID: 30131308    Free PMC article.
The age of enlightenment in melanoma immunotherapy.
Mark R Albertini.
J Immunother Cancer, 2018 Aug 24; 6(1). PMID: 30134977    Free PMC article.
Smoking Is Associated With Low Levels of Soluble PD-L1 in Rheumatoid Arthritis.
Caroline Wasén, Malin C Erlandsson, +6 authors, Maria I Bokarewa.
Front Immunol, 2018 Aug 25; 9. PMID: 30140263    Free PMC article.
High-dimensional single cell analysis identifies stem-like cytotoxic CD8+ T cells infiltrating human tumors.
Jolanda Brummelman, Emilia M C Mazza, +10 authors, Enrico Lugli.
J Exp Med, 2018 Aug 30; 215(10). PMID: 30154266    Free PMC article.
Highly Cited.
Magnetic resonance imaging and molecular features associated with tumor-infiltrating lymphocytes in breast cancer.
Jia Wu, Xuejie Li, +4 authors, Ruijiang Li.
Breast Cancer Res, 2018 Sep 05; 20(1). PMID: 30176944    Free PMC article.
Topography of cancer-associated immune cells in human solid tumors.
Jakob Nikolas Kather, Meggy Suarez-Carmona, +17 authors, Niels Halama.
Elife, 2018 Sep 05; 7. PMID: 30179157    Free PMC article.
Highly Cited.
The Combined Use of Melatonin and an Indoleamine 2,3-Dioxygenase-1 Inhibitor Enhances Vaccine-Induced Protective Cellular Immunity to HPV16-Associated Tumors.
Ana C R Moreno, Bruna F M M Porchia, +8 authors, Luís C de Souza Ferreira.
Front Immunol, 2018 Sep 07; 9. PMID: 30186285    Free PMC article.
Plasticity of Type I Interferon-Mediated Responses in Cancer Therapy: From Anti-tumor Immunity to Resistance.
Megha Budhwani, Roberta Mazzieri, Riccardo Dolcetti.
Front Oncol, 2018 Sep 07; 8. PMID: 30186768    Free PMC article.
Natural killer cells induce distinct modes of cancer cell death: Discrimination, quantification, and modulation of apoptosis, necrosis, and mixed forms.
Christian S Backes, Kim S Friedmann, +3 authors, Carsten Kummerow.
J Biol Chem, 2018 Sep 08; 293(42). PMID: 30190323    Free PMC article.
Dendritic cell vaccines for melanoma: past, present and future.
Robert O Dillman, Gabriel I Nistor, Andrew N Cornforth.
Melanoma Manag, 2016 Dec 01; 3(4). PMID: 30190899    Free PMC article.
Present and future of cancer immunotherapy: A tumor microenvironmental perspective.
Yu Yu, Jiuwei Cui.
Oncol Lett, 2018 Sep 15; 16(4). PMID: 30214551    Free PMC article.
Molecular Recalibration of PD-1+ Antigen-Specific T Cells from Blood and Liver.
Itziar Otano, David Escors, +14 authors, Mala K Maini.
Mol Ther, 2018 Sep 16; 26(11). PMID: 30217730    Free PMC article.
Heating it up: Oncolytic viruses make tumors 'hot' and suitable for checkpoint blockade immunotherapies.
Shashi Gujar, Jonathan G Pol, Guido Kroemer.
Oncoimmunology, 2018 Sep 18; 7(8). PMID: 30221036    Free PMC article.
Oncolytic vaccines increase the response to PD-L1 blockade in immunogenic and poorly immunogenic tumors.
S Feola, C Capasso, +9 authors, V Cerullo.
Oncoimmunology, 2018 Sep 18; 7(8). PMID: 30221051    Free PMC article.
CRISPR/Cas9‑mediated hypoxia inducible factor‑1α knockout enhances the antitumor effect of transarterial embolization in hepatocellular carcinoma.
Quan Liu, Dahua Fan, +9 authors, Li-Ping Liu.
Oncol Rep, 2018 Sep 19; 40(5). PMID: 30226584    Free PMC article.
BSA-bioinspired gold nanorods loaded with immunoadjuvant for the treatment of melanoma by combined photothermal therapy and immunotherapy.
Benqing Zhou, Jun Song, +6 authors, Wei R Chen.
Nanoscale, 2018 Sep 21; 10(46). PMID: 30232481    Free PMC article.
Comparison of Protein and Peptide Targeting for the Development of a CD169-Based Vaccination Strategy Against Melanoma.
Dieke van Dinther, Henrike Veninga, +7 authors, Joke M M den Haan.
Front Immunol, 2018 Sep 22; 9. PMID: 30237798    Free PMC article.
Blockade of Na/H exchanger stimulates glioma tumor immunogenicity and enhances combinatorial TMZ and anti-PD-1 therapy.
Xiudong Guan, Md Nabiul Hasan, +7 authors, Dandan Sun.
Cell Death Dis, 2018 Sep 29; 9(10). PMID: 30262908    Free PMC article.
Gut microbiota, chemotherapy and the host: the influence of the gut microbiota on cancer treatment.
Anna Louise Pouncey, Alasdair James Scott, +2 authors, James Kinross.
Ecancermedicalscience, 2018 Sep 29; 12. PMID: 30263059    Free PMC article.
RNAi-Mediated β-Catenin Inhibition Promotes T Cell Infiltration and Antitumor Activity in Combination with Immune Checkpoint Blockade.
Shanthi Ganesh, Xue Shui, +4 authors, Marc T Abrams.
Mol Ther, 2018 Oct 03; 26(11). PMID: 30274786    Free PMC article.
The systemic immune-inflammation index is an independent predictor of survival for metastatic colorectal cancer and its association with the lymphocytic response to the tumor.
Qian-Kun Xie, Ping Chen, +10 authors, Liang-Ping Xia.
J Transl Med, 2018 Oct 06; 16(1). PMID: 30286769    Free PMC article.
Biochemical Aspects of PD-L1 Regulation in Cancer Immunotherapy.
Jinfang Zhang, Fabin Dang, Junming Ren, Wenyi Wei.
Trends Biochem Sci, 2018 Oct 06; 43(12). PMID: 30287140    Free PMC article.
Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma.
David L Bajor, Rosemarie Mick, +15 authors, Robert H Vonderheide.
Oncoimmunology, 2018 Oct 06; 7(10). PMID: 30288340    Free PMC article.
A Single-Chain-Based Hexavalent CD27 Agonist Enhances T Cell Activation and Induces Anti-Tumor Immunity.
Meinolf Thiemann, David M Richards, +10 authors, Oliver Hill.
Front Oncol, 2018 Oct 10; 8. PMID: 30298117    Free PMC article.
Translational Potential of Therapeutics Targeting Regulatory Myeloid Cells in Tuberculosis.
Nelita du Plessis, Leigh A Kotze, Vinzeigh Leukes, Gerhard Walzl.
Front Cell Infect Microbiol, 2018 Oct 10; 8. PMID: 30298121    Free PMC article.
Expression of the Immune Checkpoint Modulator OX40 in Acute Lymphoblastic Leukemia Is Associated with BCR-ABL Positivity.
Kathrin Rothfelder, Ilona Hagelstein, +6 authors, Daniela Dörfel.
Neoplasia, 2018 Oct 10; 20(11). PMID: 30300827    Free PMC article.
Diosgenin promotes antitumor immunity and PD-1 antibody efficacy against melanoma by regulating intestinal microbiota.
Mengxue Dong, Zhefeng Meng, +7 authors, Li Ye.
Cell Death Dis, 2018 Oct 12; 9(10). PMID: 30305604    Free PMC article.
Tobacco smoking and cessation and PD-L1 inhibitors in non-small cell lung cancer (NSCLC): a review of the literature.
Jan Norum, Carsten Nieder.
ESMO Open, 2018 Oct 12; 3(6). PMID: 30305940    Free PMC article.
Checkpoint Blockade Reverses Anergy in IL-13Rα2 Humanized scFv-Based CAR T Cells to Treat Murine and Canine Gliomas.
Yibo Yin, Alina C Boesteanu, +20 authors, Laura A Johnson.
Mol Ther Oncolytics, 2018 Oct 12; 11. PMID: 30306125    Free PMC article.
On the Road to Immunotherapy-Prospects for Treating Head and Neck Cancers With Checkpoint Inhibitor Antibodies.
Frank J Ward, Lekh N Dahal, Rasha Abu-Eid.
Front Immunol, 2018 Oct 16; 9. PMID: 30319637    Free PMC article.
Checkpoint Inhibition in Myeloma: Opportunities and Challenges.
Federica Costa, Rituparna Das, +2 authors, Madhav V Dhodapkar.
Front Immunol, 2018 Oct 16; 9. PMID: 30319648    Free PMC article.
Immunogenic effects of chemotherapy-induced tumor cell death.
Yi-Jun Wang, Rochelle Fletcher, Jian Yu, Lin Zhang.
Genes Dis, 2018 Oct 16; 5(3). PMID: 30320184    Free PMC article.
Highly Cited. Review.
[Immunological foundations of modern (tumor) immunotherapy].
T Bopp, H Schild.
Pathologe, 2018 Oct 18; 39(6). PMID: 30327859

;. PMID: 30345161
Highly Cited.
Homology-Directed Repair and the Role of BRCA1, BRCA2, and Related Proteins in Genome Integrity and Cancer.
Chun-Chin Chen, Weiran Feng, +2 authors, Maria Jasin.
Annu Rev Cancer Biol, 2018 Oct 23; 2. PMID: 30345412    Free PMC article.
Highly Cited.
Diamonds in the Rough: Harnessing Tumor-Associated Myeloid Cells for Cancer Therapy.
Emile J Clappaert, Aleksandar Murgaski, +2 authors, Damya Laoui.
Front Immunol, 2018 Oct 24; 9. PMID: 30349530    Free PMC article.
Characteristics and outcomes of patients with recurrent ovarian cancer undergoing early phase immune checkpoint inhibitor clinical trials.
Emily Hinchcliff, David Hong, +5 authors, Amir Jazaeri.
Gynecol Oncol, 2018 Oct 28; 151(3). PMID: 30366646    Free PMC article.
Blood handling and leukocyte isolation methods impact the global transcriptome of immune cells.
Brittany A Goods, Jacqueline M Vahey, +3 authors, J Christopher Love.
BMC Immunol, 2018 Nov 01; 19(1). PMID: 30376808    Free PMC article.
Recent advances in immunotherapies: from infection and autoimmunity, to cancer, and back again.
Samantha L Bucktrout, Jeffrey A Bluestone, Fred Ramsdell.
Genome Med, 2018 Nov 01; 10(1). PMID: 30376867    Free PMC article.
Targeting IFNα to tumor by anti-PD-L1 creates feedforward antitumor responses to overcome checkpoint blockade resistance.
Yong Liang, Haidong Tang, +12 authors, Yang-Xin Fu.
Nat Commun, 2018 Nov 06; 9(1). PMID: 30389912    Free PMC article.
Adipose PD-L1 Modulates PD-1/PD-L1 Checkpoint Blockade Immunotherapy Efficacy in Breast Cancer.
Bogang Wu, Xiujie Sun, +11 authors, Rong Li.
Oncoimmunology, 2018 Nov 06; 7(11). PMID: 30393583    Free PMC article.
The efficacy and safety of immune checkpoint inhibitor combination therapy in lung cancer: a systematic review and meta-analysis.
Min Peng, Xing Li, +3 authors, Qi Bin Song.
Onco Targets Ther, 2018 Nov 15; 11. PMID: 30425525    Free PMC article.
Clinical and molecular characteristics associated with the efficacy of PD-1/PD-L1 inhibitors for solid tumors: a meta-analysis.
Yi Ming Weng, Min Peng, +2 authors, Qi Bin Song.
Onco Targets Ther, 2018 Nov 23; 11. PMID: 30464501    Free PMC article.
Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO-1 Pathway.
Jianqin Lu, Xiangsheng Liu, +6 authors, Andre E Nel.
ACS Nano, 2018 Nov 30; 12(11). PMID: 30481959    Free PMC article.
Soluble immune checkpoints in cancer: production, function and biological significance.
Daqian Gu, Xiang Ao, +2 authors, Xiang Xu.
J Immunother Cancer, 2018 Nov 30; 6(1). PMID: 30482248    Free PMC article.
Genomics of response to immune checkpoint therapies for cancer: implications for precision medicine.
Jake R Conway, Eric Kofman, +2 authors, Eliezer Van Allen.
Genome Med, 2018 Dec 01; 10(1). PMID: 30497521    Free PMC article.
Measuring tumor mutation burden in non-small cell lung cancer: tissue versus liquid biopsy.
Francesca Fenizia, Raffaella Pasquale, +3 authors, Nicola Normanno.
Transl Lung Cancer Res, 2018 Dec 07; 7(6). PMID: 30505711    Free PMC article.
PD-L1 expression with immune-infiltrate evaluation and outcome prediction in melanoma patients treated with ipilimumab.
Gabriele Madonna, Carmen Ballesteros-Merino, +10 authors, Paolo A Ascierto.
Oncoimmunology, 2018 Dec 14; 7(12). PMID: 30524879    Free PMC article.
Actin stabilizer TAGLN2 potentiates adoptive T cell therapy by boosting the inside-out costimulation via lymphocyte function-associated antigen-1.
Bu-Nam Jeon, Hye-Ran Kim, +7 authors, Chang-Duk Jun.
Oncoimmunology, 2018 Dec 14; 7(12). PMID: 30524895    Free PMC article.
Trial watch: Peptide-based vaccines in anticancer therapy.
Lucillia Bezu, Oliver Kepp, +6 authors, Lorenzo Galluzzi.
Oncoimmunology, 2018 Dec 14; 7(12). PMID: 30524907    Free PMC article.
Highly Cited. Review.
The Roles of Coinhibitory Receptors in Pathogenesis of Human Retroviral Infections.
Keiko Yasuma-Mitobe, Masao Matsuoka.
Front Immunol, 2018 Dec 13; 9. PMID: 30538707    Free PMC article.
Targeting natural killer cells in solid tumors.
Guillaume Habif, Adeline Crinier, +2 authors, Emilie Narni-Mancinelli.
Cell Mol Immunol, 2019 Mar 27; 16(5). PMID: 30911118    Free PMC article.
Highly Cited. Review.
Enrichment of melanoma-associated T cells in 6-thioguanine-resistant T cells from metastatic melanoma patients.
Cindy L Zuleger, Michael A Newton, +3 authors, Mark R Albertini.
Melanoma Res, 2019 May 29; 30(1). PMID: 31135600    Free PMC article.
Improved Prognosis and Increased Tumor-Infiltrating Lymphocytes in Patients Who Have SCLC With Neurologic Paraneoplastic Syndromes.
Wade T Iams, Eileen Shiuan, +10 authors, Christine M Lovly.
J Thorac Oncol, 2019 Jun 16; 14(11). PMID: 31201935    Free PMC article.
Application of PD-1 Blockade in Cancer Immunotherapy.
Xiaomo Wu, Zhongkai Gu, +4 authors, Xiaolong Liu.
Comput Struct Biotechnol J, 2019 Jun 18; 17. PMID: 31205619    Free PMC article.
Highly Cited. Review.
Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation.
Alex M Jaeger, Lauren Stopfer, +9 authors, Luke Whitesell.
Clin Cancer Res, 2019 Jun 20; 25(21). PMID: 31213460    Free PMC article.
Inflammation and Cancer: Triggers, Mechanisms, and Consequences.
Florian R Greten, Sergei I Grivennikov.
Immunity, 2019 Jul 18; 51(1). PMID: 31315034    Free PMC article.
Highly Cited. Review.
Primary tumors induce neutrophil extracellular traps with targetable metastasis promoting effects.
Roni F Rayes, Jack G Mouhanna, +10 authors, Jonathan D Spicer.
JCI Insight, 2019 Jul 26; 5. PMID: 31343990    Free PMC article.
Characterizing Thermal Transitions of IgG with Mass Spectrometry.
Christopher J Brown, Daniel W Woodall, Tarick J El-Baba, David E Clemmer.
J Am Soc Mass Spectrom, 2019 Aug 01; 30(11). PMID: 31363989    Free PMC article.
Localized Treatment with Oncolytic Adenovirus Delta-24-RGDOX Induces Systemic Immunity against Disseminated Subcutaneous and Intracranial Melanomas.
Hong Jiang, Dong Ho Shin, +10 authors, Candelaria Gomez-Manzano.
Clin Cancer Res, 2019 Aug 29; 25(22). PMID: 31455679    Free PMC article.
Heat Shock Proteins Are Essential Components in Transformation and Tumor Progression: Cancer Cell Intrinsic Pathways and Beyond.
Benjamin J Lang, Martín Eduardo Guerrero-Giménez, +3 authors, Stuart K Calderwood.
Int J Mol Sci, 2019 Sep 14; 20(18). PMID: 31514477    Free PMC article.
αvβ3-integrin regulates PD-L1 expression and is involved in cancer immune evasion.
Andrea Vannini, Valerio Leoni, +5 authors, Tatiana Gianni.
Proc Natl Acad Sci U S A, 2019 Sep 19; 116(40). PMID: 31527243    Free PMC article.
Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges.
Muhammad Zaeem Noman, Meriem Hasmim, +5 authors, Bassam Janji.
Cells, 2019 Sep 22; 8(9). PMID: 31540045    Free PMC article.
Blockade of PD-L1 Enhances Cancer Immunotherapy by Regulating Dendritic Cell Maturation and Macrophage Polarization.
Nai-Yun Sun, Yu-Li Chen, +8 authors, Wen-Fang Cheng.
Cancers (Basel), 2019 Sep 25; 11(9). PMID: 31546897    Free PMC article.
Molecular Modeling Studies on the Binding Mode of the PD-1/PD-L1 Complex Inhibitors.
Suliman Almahmoud, Haizhen A Zhong.
Int J Mol Sci, 2019 Sep 25; 20(18). PMID: 31546905    Free PMC article.
The Evolving Landscape of Biomarkers for Anti-PD-1 or Anti-PD-L1 Therapy.
Antje Tunger, Ulrich Sommer, +7 authors, Marc Schmitz.
J Clin Med, 2019 Sep 29; 8(10). PMID: 31557787    Free PMC article.
Atractylodes macrocephala polysaccharides regulate the innate immunity of colorectal cancer cells by modulating the TLR4 signaling pathway.
Zifang Feng, Ruibin Yang, +5 authors, Yonghuai Feng.
Onco Targets Ther, 2019 Oct 01; 12. PMID: 31564895    Free PMC article.
Current applications and future prospects of nanotechnology in cancer immunotherapy.
Sen Yan, Peng Zhao, Tingting Yu, Ning Gu.
Cancer Biol Med, 2019 Oct 01; 16(3). PMID: 31565479    Free PMC article.
Antipsychotic Drug Trifluoperazine Suppresses Colorectal Cancer by Inducing G0/G1 Arrest and Apoptosis.
Yong Xia, Chengsen Jia, +7 authors, Tinghong Ye.
Front Pharmacol, 2019 Oct 02; 10. PMID: 31572198    Free PMC article.
Expression of Programmed Cell Death-Ligands in Hepatocellular Carcinoma: Correlation With Immune Microenvironment and Survival Outcomes.
Haotian Liao, Wen Chen, +5 authors, Kunlin Xie.
Front Oncol, 2019 Oct 02; 9. PMID: 31572677    Free PMC article.
Enumeration And Characterization Of Circulating Tumor Cells And Its Application In Advanced Gastric Cancer.
Boran Cheng, Gangling Tong, +6 authors, Shubin Wang.
Onco Targets Ther, 2019 Oct 03; 12. PMID: 31576146    Free PMC article.
New insights in predictive determinants of the tumor immune microenvironment for immune checkpoint inhibition: a never ending story?
Markus Eckstein, Shilpa Gupta.
Ann Transl Med, 2019 Oct 03; 7(Suppl 3). PMID: 31576342    Free PMC article.
HHLA2 is a novel prognostic predictor and potential therapeutic target in malignant glioma.
Yangzhi Qi, Gang Deng, +6 authors, Qianxue Chen.
Oncol Rep, 2019 Oct 04; 42(6). PMID: 31578594    Free PMC article.
STAT3 Activity Promotes Programmed-Death Ligand 1 Expression and Suppresses Immune Responses in Breast Cancer.
Ioannis Zerdes, Majken Wallerius, +10 authors, Theodoros Foukakis.
Cancers (Basel), 2019 Oct 05; 11(10). PMID: 31581535    Free PMC article.
Predicting response to pembrolizumab in metastatic melanoma by a new personalization algorithm.
Neta Tsur, Yuri Kogan, +5 authors, Zvia Agur.
J Transl Med, 2019 Oct 09; 17(1). PMID: 31590677    Free PMC article.
Immuno-Oncology Therapy for Hepatocellular Carcinoma: Current Status and Ongoing Trials.
Masatoshi Kudo.
Liver Cancer, 2019 Oct 12; 8(4). PMID: 31602367    Free PMC article.
The Course of Immune Stimulation by Photodynamic Therapy: Bridging Fundamentals of Photochemically Induced Immunogenic Cell Death to the Enrichment of T-Cell Repertoire.
Shubhankar Nath, Girgis Obaid, Tayyaba Hasan.
Photochem Photobiol, 2019 Oct 12; 95(6). PMID: 31602649    Free PMC article.
GITRL-armed Delta-24-RGD oncolytic adenovirus prolongs survival and induces anti-glioma immune memory.
Yisel Rivera-Molina, Hong Jiang, +9 authors, Candelaria Gomez-Manzano.
Neurooncol Adv, 2019 Oct 15; 1(1). PMID: 31608328    Free PMC article.
CTLA-4 Immunohistochemistry and Quantitative Image Analysis for Profiling of Human Cancers.
Charles Brown, Farzad Sekhavati, +4 authors, Keith E Steele.
J Histochem Cytochem, 2019 Oct 15; 67(12). PMID: 31609157    Free PMC article.
Autoimmune antibodies correlate with immune checkpoint therapy-induced toxicities.
Salahaldin A Tahir, Jianjun Gao, +9 authors, Padmanee Sharma.
Proc Natl Acad Sci U S A, 2019 Oct 16; 116(44). PMID: 31611368    Free PMC article.
Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity.
Guangchuan Wang, Ryan D Chow, +12 authors, Sidi Chen.
Nat Immunol, 2019 Oct 16; 20(11). PMID: 31611701    Free PMC article.
A spatial similarity of stereochemical environments formed by amino acid residues defines a common epitope of two non-homologous proteins.
Kentaro Nakashima, Shintaro Iwashita, +8 authors, Si-Young Song.
Sci Rep, 2019 Oct 17; 9(1). PMID: 31616018    Free PMC article.
Correlation between subsets of tumor-infiltrating immune cells and risk stratification in patients with cervical cancer.
Rui Chen, Yi Gong, +3 authors, Qi Zhou.
PeerJ, 2019 Oct 17; 7. PMID: 31616592    Free PMC article.
PD-1-Associated Gene Expression Signature of Neoadjuvant Trastuzumab-Treated Tumors Correlates with Patient Survival in HER2-Positive Breast Cancer.
William P D Hendricks, Natalia Briones, +4 authors, Suwon Kim.
Cancers (Basel), 2019 Oct 18; 11(10). PMID: 31618954    Free PMC article.
Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8+ T lymphocyte exhaustion.
Alessandro Ascione, Claudia Arenaccio, +7 authors, Maurizio Federico.
BMC Biotechnol, 2019 Oct 19; 19(1). PMID: 31623599    Free PMC article.
Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease.
Peter A Szabo, Hanna Mendes Levitin, +9 authors, Peter A Sims.
Nat Commun, 2019 Oct 19; 10(1). PMID: 31624246    Free PMC article.
ImmunoPET imaging of CD38 expression in hepatocellular carcinoma using 64Cu-labeled daratumumab.
Shiyong Li, Christopher G England, +4 authors, Weibo Cai.
Am J Transl Res, 2019 Oct 22; 11(9). PMID: 31632568    Free PMC article.
Combination anti-CTLA-4 plus anti-PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies.
Spencer C Wei, Nana-Ama A S Anang, +8 authors, James P Allison.
Proc Natl Acad Sci U S A, 2019 Oct 23; 116(45). PMID: 31636208    Free PMC article.
The Diverse Function of PD-1/PD-L Pathway Beyond Cancer.
Weiting Qin, Lipeng Hu, +4 authors, Xu Wang.
Front Immunol, 2019 Oct 23; 10. PMID: 31636634    Free PMC article.
Highly Cited. Review.
CMTM6, the newly identified PD-L1 regulator, correlates with PD-L1 expression in lung cancers.
Feng Gao, Jing Chen, +4 authors, Yong Ji.
Biochem Biophys Rep, 2019 Oct 28; 20. PMID: 31646201    Free PMC article.
Discovering myeloid cell heterogeneity in the lung by means of next generation sequencing.
Jing-Jing Ji, Jie Fan.
Mil Med Res, 2019 Oct 28; 6(1). PMID: 31651369    Free PMC article.
Adverse Events of Concurrent Immune Checkpoint Inhibitors and Antiangiogenic Agents: A Systematic Review.
Ling Gao, Xi Yang, Cheng Yi, Hong Zhu.
Front Pharmacol, 2019 Nov 05; 10. PMID: 31680957    Free PMC article.
Systematic Review.
Immunostimulatory RNA leads to functional reprogramming of myeloid-derived suppressor cells in pancreatic cancer.
Philipp Metzger, Sabrina V Kirchleitner, +10 authors, Peter Duewell.
J Immunother Cancer, 2019 Nov 07; 7(1). PMID: 31694706    Free PMC article.
Tumor-Associated Macrophages (TAMs): A Critical Activator In Ovarian Cancer Metastasis.
Meichen Yin, Jiayu Shen, +6 authors, Jianwei Zhou.
Onco Targets Ther, 2019 Nov 07; 12. PMID: 31695427    Free PMC article.
Nanoparticle Delivery of Immunostimulatory Agents for Cancer Immunotherapy.
Jia Zhuang, Maya Holay, +3 authors, Liangfang Zhang.
Theranostics, 2019 Nov 07; 9(25). PMID: 31695803    Free PMC article.
Adoption of immunotherapy in the community for patients diagnosed with metastatic melanoma.
Marieke J Krimphove, Karl H Tully, +9 authors, Quoc-Dien Trinh.
J Immunother Cancer, 2019 Nov 09; 7(1). PMID: 31699149    Free PMC article.
Prognostic Value of Programmed Cell Death Ligand-1 Expression in Nasopharyngeal Carcinoma: A Meta-Analysis of 1,315 Patients.
Xiaofeng Liu, Chunguang Shan, Yingluan Song, Juan Du.
Front Oncol, 2019 Nov 12; 9. PMID: 31709181    Free PMC article.
Systematic Review.
Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer.
So Mee Kwon, Anuradha Budhu, +10 authors, Xin Wei Wang.
Sci Rep, 2019 Nov 16; 9(1). PMID: 31729408    Free PMC article.
Engineering Nanoparticles to Reprogram the Tumor Immune Microenvironment for Improved Cancer Immunotherapy.
Madiha Saeed, Jing Gao, +2 authors, Haijun Yu.
Theranostics, 2019 Nov 23; 9(26). PMID: 31754376    Free PMC article.
Cancer Cell Metabolism: Implications for X-ray and Particle Radiation Therapy.
Mathieu Sertorio, John P Perentesis, +3 authors, Susanne I Wells.
Int J Part Ther, 2018 Jul 01; 5(1). PMID: 31773019    Free PMC article.
A Case of Severe Seronegative Inflammatory Arthritis due to Nivolumab and Review of the Literature.
Bicky Thapa, Asad Ali, +2 authors, Cassandra Calabrese.
Case Rep Rheumatol, 2019 Nov 30; 2019. PMID: 31781462    Free PMC article.
Computational Insight Into the Small Molecule Intervening PD-L1 Dimerization and the Potential Structure-Activity Relationship.
Danfeng Shi, Xiaoli An, +4 authors, Xiaojun Yao.
Front Chem, 2019 Nov 30; 7. PMID: 31781546    Free PMC article.
PD1Hi CD8+ T cells correlate with exhausted signature and poor clinical outcome in hepatocellular carcinoma.
Jiaqiang Ma, Bohao Zheng, +12 authors, Xiaoming Zhang.
J Immunother Cancer, 2019 Dec 01; 7(1). PMID: 31783783    Free PMC article.
Global alteration of T-lymphocyte metabolism by PD-L1 checkpoint involves a block of de novo nucleoside phosphate synthesis.
Nicolaos Jay Palaskas, Jacob David Garcia, +5 authors, Thomas Glen Graeber.
Cell Discov, 2019 Dec 05; 5. PMID: 31798961    Free PMC article.
Hyperprogressive Disease In Cervical Small Cell Carcinoma Treated By Immune Checkpoint Inhibitor.
Zihan Xu, Liying Chen, +6 authors, Jianguo Sun.
Onco Targets Ther, 2019 Dec 06; 12. PMID: 31802899    Free PMC article.
B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer.
Daniel P Hollern, Nuo Xu, +15 authors, Charles M Perou.
Cell, 2019 Nov 16; 179(5). PMID: 31730857    Free PMC article.
Neoantigens and genome instability: impact on immunogenomic phenotypes and immunotherapy response.
Elaine R Mardis.
Genome Med, 2019 Nov 22; 11(1). PMID: 31747945    Free PMC article.
Overexpressed ITGA2 promotes malignant tumor aggression by up-regulating PD-L1 expression through the activation of the STAT3 signaling pathway.
Dianyun Ren, Jingyuan Zhao, +7 authors, Heshui Wu.
J Exp Clin Cancer Res, 2019 Dec 11; 38(1). PMID: 31818309    Free PMC article.
Epigenetic polypharmacology: A new frontier for epi-drug discovery.
Daniela Tomaselli, Alessia Lucidi, Dante Rotili, Antonello Mai.
Med Res Rev, 2019 Jun 21; 40(1). PMID: 31218726    Free PMC article.
A flexible design for advanced Phase I/II clinical trials with continuous efficacy endpoints.
Pavel Mozgunov, Thomas Jaki.
Biom J, 2019 Jul 13; 61(6). PMID: 31298770    Free PMC article.
Receptor-Interacting Protein Kinase 3 Deficiency Recruits Myeloid-Derived Suppressor Cells to Hepatocellular Carcinoma Through the Chemokine (C-X-C Motif) Ligand 1-Chemokine (C-X-C Motif) Receptor 2 Axis.
Yi-Ming Li, Zhen-Yu Liu, +5 authors, Zhi-Nan Chen.
Hepatology, 2019 Apr 26; 70(5). PMID: 31021443    Free PMC article.
Blockage of immune checkpoint molecules increases T-cell priming potential of dendritic cell vaccine.
Hadi Hassannia, Mitra Ghasemi Chaleshtari, +11 authors, Farhad Jadidi-Niaragh.
Immunology, 2019 Oct 07; 159(1). PMID: 31587253    Free PMC article.
PD-L1 expression correlated with p53 expression in oral squamous cell carcinoma.
Itaru Tojyo, Yukari Shintani, +6 authors, Yasuteru Muragaki.
Maxillofac Plast Reconstr Surg, 2019 Dec 21; 41(1). PMID: 31857991    Free PMC article.
Sequential Ipilimumab After Chemoradiotherapy in Curative-Intent Treatment of Patients With Node-Positive Cervical Cancer.
Jyoti S Mayadev, Danielle Enserro, +8 authors, Russell J Schilder.
JAMA Oncol, 2019 Nov 28; 6(1). PMID: 31774464    Free PMC article.
Bacteriotherapy in Breast Cancer.
Atieh Yaghoubi, Majid Khazaei, +3 authors, Saman Soleimanpour.
Int J Mol Sci, 2019 Nov 28; 20(23). PMID: 31771178    Free PMC article.
A systematic analysis of immune genes and overall survival in cancer patients.
Qian Wang, Pan Li, Weidong Wu.
BMC Cancer, 2019 Dec 18; 19(1). PMID: 31842801    Free PMC article.
Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy.
Jun Wei, Lingyun Long, +14 authors, Hongbo Chi.
Nature, 2019 Dec 13; 576(7787). PMID: 31827283    Free PMC article.
AGI-134: a fully synthetic α-Gal glycolipid that converts tumors into in situ autologous vaccines, induces anti-tumor immunity and is synergistic with an anti-PD-1 antibody in mouse melanoma models.
Stephen M Shaw, Jenny Middleton, +13 authors, Sascha A Kristian.
Cancer Cell Int, 2020 Jan 01; 19. PMID: 31889898    Free PMC article.
Tissue-Resident Memory T Cells Mediate Immune Homeostasis in the Human Pancreas through the PD-1/PD-L1 Pathway.
Stuart P Weisberg, Dustin J Carpenter, +14 authors, Donna L Farber.
Cell Rep, 2019 Dec 19; 29(12). PMID: 31851923    Free PMC article.
A generic cell surface ligand system for studying cell-cell recognition.
Eleanor M Denham, Michael I Barton, +5 authors, Jesse Goyette.
PLoS Biol, 2019 Dec 10; 17(12). PMID: 31815943    Free PMC article.
Personal response to immune checkpoint inhibitors of patients with advanced melanoma explained by a computational model of cellular immunity, tumor growth, and drug.
D Perlstein, O Shlagman, +4 authors, Z Agur.
PLoS One, 2019 Dec 27; 14(12). PMID: 31877168    Free PMC article.
Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade.
Nicolas Jacquelot, Takahiro Yamazaki, +30 authors, Laurence Zitvogel.
Cell Res, 2019 Sep 05; 29(10). PMID: 31481761    Free PMC article.
Combined Vaccination with NY-ESO-1 Protein, Poly-ICLC, and Montanide Improves Humoral and Cellular Immune Responses in Patients with High-Risk Melanoma.
Anna Pavlick, Ana B Blazquez, +12 authors, Nina Bhardwaj.
Cancer Immunol Res, 2019 Nov 09; 8(1). PMID: 31699709    Free PMC article.
Steroid-responsive Nivolumab-induced Involuntary Movement with Anti-thyroid Antibodies.
Yuta Maetani, Tomohisa Nezu, +3 authors, Hirofumi Maruyama.
Intern Med, 2019 Aug 30; 58(24). PMID: 31462589    Free PMC article.
Siah2 control of T-regulatory cells limits anti-tumor immunity.
Marzia Scortegagna, Kathryn Hockemeyer, +13 authors, Ze'ev A Ronai.
Nat Commun, 2020 Jan 09; 11(1). PMID: 31911617    Free PMC article.
Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses.
Weng In Leong, Rachel Y Ames, +8 authors, Mary J Janatpour.
Oncotarget, 2020 Jan 11; 10(68). PMID: 31921384    Free PMC article.
Lymph Node Metastasis From Gastroesophageal Cancer Successfully Treated by Nivolumab: A Case Report of a Young Patient.
Shin Kashima, Hiroki Tanabe, +15 authors, Toshikatsu Okumura.
Front Oncol, 2020 Jan 11; 9. PMID: 31921639    Free PMC article.
Safety and Efficacy in Relapsed or Refractory Classic Hodgkin's Lymphoma Treated with PD-1 Inhibitors: A Meta-Analysis of 9 Prospective Clinical Trials.
Xueyan Zhang, Li Chen, +3 authors, Miao He.
Biomed Res Int, 2020 Jan 18; 2019. PMID: 31950058    Free PMC article.
A Graphene-Based Glycan Biosensor for Electrochemical Label-Free Detection of a Tumor-Associated Antibody.
Filip Kveton, Anna Blsakova, +6 authors, Jan Tkac.
Sensors (Basel), 2019 Dec 11; 19(24). PMID: 31818011    Free PMC article.
The integrated stress response promotes B7H6 expression.
Akram Obiedat, Yoav Charpak-Amikam, +12 authors, Boaz Tirosh.
J Mol Med (Berl), 2019 Dec 16; 98(1). PMID: 31838577    Free PMC article.
Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors.
Sadal Refae, Jocelyn Gal, +7 authors, Esma Saada-Bouzid.
Invest New Drugs, 2019 Aug 14; 38(1). PMID: 31402427
Potential role of the PD-L1 expression and tumor-infiltrating lymphocytes on neuroblastoma.
Shogo Zuo, Masayuki Sho, +6 authors, Hiroomi Okuyama.
Pediatr Surg Int, 2020 Jan 12; 36(2). PMID: 31925505
HBD3 Induces PD-L1 Expression on Head and Neck Squamous Cell Carcinoma Cell Lines.
Maria Paula Gomez Hernandez, Amber M Bates, +4 authors, Kim A Brogden.
Antibiotics (Basel), 2019 Sep 27; 8(4). PMID: 31554151    Free PMC article.
Preclinical murine tumor models: a structural and functional perspective.
Marion V Guerin, Veronica Finisguerra, +2 authors, Alain Trautmann.
Elife, 2020 Jan 29; 9. PMID: 31990272    Free PMC article.
Prediction of hepatocellular carcinoma prognosis based on expression of an immune-related gene set.
Yuting He, Qin Dang, +4 authors, Wenzhi Guo.
Aging (Albany NY), 2020 Jan 14; 12(1). PMID: 31929113    Free PMC article.
Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology.
Isaure Vanmeerbeek, Jenny Sprooten, +8 authors, Abhishek D Garg.
Oncoimmunology, 2020 Feb 01; 9(1). PMID: 32002302    Free PMC article.
Programmed Death Ligand 1 (PD-L1) Expression in Epithelial Ovarian Cancer: A Comparison of Type I and Type II Tumors
Wilasinee Nhokaew, Pilaiwan Kleebkaow, Nipon Chaisuriya, Chumnan Kietpeerakool.
Asian Pac J Cancer Prev, 2019 Apr 30; 20(4). PMID: 31030490    Free PMC article.
Simplified Admix Archaeal Glycolipid Adjuvanted Vaccine and Checkpoint Inhibitor Therapy Combination Enhances Protection from Murine Melanoma.
Felicity C Stark, Gerard Agbayani, +8 authors, Michael J McCluskie.
Biomedicines, 2019 Nov 28; 7(4). PMID: 31771150    Free PMC article.
Uveal Melanoma.
Ulrich Pfeffer.
Cancers (Basel), 2019 Dec 15; 11(12). PMID: 31835485    Free PMC article.
Evaluation of PD-L1 and other immune markers in bladder urothelial carcinoma stratified by histologic variants and molecular subtypes.
Huili Li, Qingzhao Zhang, +6 authors, Guoli Chen.
Sci Rep, 2020 Jan 31; 10(1). PMID: 31996725    Free PMC article.
Can immune biomarkers predict benefit from targeted agents in metastatic renal cell carcinoma?
Renate Pichler, Manuela Schmidinger.
Ann Transl Med, 2020 Feb 06; 7(Suppl 8). PMID: 32015994    Free PMC article.
In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma.
Fei Li, Qingyuan Huang, +25 authors, Kwok-Kin Wong.
Cancer Discov, 2019 Nov 21; 10(2). PMID: 31744829    Free PMC article.
Immunological microenvironment gene expression in patients with diffuse large B cell non Hodgkin lymphoma.
Nesreen G Elhelbawy, Adel A H Nassar, +2 authors, Eman Ae Badr.
Biochem Biophys Rep, 2020 Feb 07; 21. PMID: 32025577    Free PMC article.
Dynamic visualization of the whole process of cytotoxic T lymphocytes killing B16 tumor cells in vitro.
Shuhong Qi, Hua Shi, +2 authors, Zhihong Zhang.
J Biomed Opt, 2019 Mar 03; 24(5). PMID: 30825298    Free PMC article.
T-cell exhaustion in HIV infection.
Craig Fenwick, Victor Joo, +4 authors, Giuseppe Pantaleo.
Immunol Rev, 2019 Dec 29; 292(1). PMID: 31883174    Free PMC article.
Characterization of LAG-3, CTLA-4, and CD8+ TIL density and their joint influence on the prognosis of patients with esophageal squamous cell carcinoma.
Wenjia Wang, Donglai Chen, +7 authors, Yongbing Chen.
Ann Transl Med, 2020 Feb 12; 7(23). PMID: 32042792    Free PMC article.
The role of RICTOR amplification in targeted therapy and drug resistance.
Deze Zhao, Man Jiang, Xiaochun Zhang, Helei Hou.
Mol Med, 2020 Feb 12; 26(1). PMID: 32041519    Free PMC article.
DNA Nanostructure as an Efficient Drug Delivery Platform for Immunotherapy.
Qingjia Chi, Zichang Yang, +2 authors, Huaping Liang.
Front Pharmacol, 2020 Feb 18; 10. PMID: 32063844    Free PMC article.
Blockade of Stat3 oncogene addiction induces cellular senescence and reveals a cell-nonautonomous activity suitable for cancer immunotherapy.
Mara De Martino, Mercedes Tkach, +11 authors, Roxana Schillaci.
Oncoimmunology, 2020 Feb 18; 9(1). PMID: 32064174    Free PMC article.
Discovery of BMS-986260, a Potent, Selective, and Orally Bioavailable TGFβR1 Inhibitor as an Immuno-oncology Agent.
Upender Velaparthi, Chetan Padmakar Darne, +29 authors, Robert M Borzilleri.
ACS Med Chem Lett, 2020 Feb 20; 11(2). PMID: 32071685    Free PMC article.
Immunotherapies for pediatric cancer: current landscape and future perspectives.
Brian Hutzen, Siddhi Nath Paudel, +3 authors, Timothy P Cripe.
Cancer Metastasis Rev, 2019 Dec 13; 38(4). PMID: 31828566    Free PMC article.
Dual pH-sensitive nanodrug blocks PD-1 immune checkpoint and uses T cells to deliver NF-κB inhibitor for antitumor immunotherapy.
Zecong Xiao, Zhenwei Su, +3 authors, Xintao Shuai.
Sci Adv, 2020 Feb 23; 6(6). PMID: 32076650    Free PMC article.
Advances in Anti-Tumor Treatments Targeting the CD47/SIRPα Axis.
Wenting Zhang, Qinghua Huang, +7 authors, Hua Jin.
Front Immunol, 2020 Feb 23; 11. PMID: 32082311    Free PMC article.
Cdk5 knocking out mediated by CRISPR-Cas9 genome editing for PD-L1 attenuation and enhanced antitumor immunity.
Huan Deng, Songwei Tan, +7 authors, Zhiping Zhang.
Acta Pharm Sin B, 2020 Feb 23; 10(2). PMID: 32082979    Free PMC article.
Cancer immunotherapy with immunoadjuvants, nanoparticles, and checkpoint inhibitors: Recent progress and challenges in treatment and tracking response to immunotherapy.
Michael-Joseph Gorbet, Ashish Ranjan.
Pharmacol Ther, 2019 Dec 22; 207. PMID: 31863820    Free PMC article.
Tumor Evolution: A Problem of Histocompatibility.
Natalie I Vokes, Eliezer M Van Allen.
Cell, 2017 Dec 02; 171(6). PMID: 29195070    Free PMC article.
Immune Checkpoint Inhibitor Myocarditis: Pathophysiological Characteristics, Diagnosis, and Treatment.
Nicolas Palaskas, Juan Lopez-Mattei, +2 authors, Anita Deswal.
J Am Heart Assoc, 2020 Jan 22; 9(2). PMID: 31960755    Free PMC article.
Increased Expression of Programmed Death-Ligand 1 in Infiltrating Immune Cells in Hepatocellular Carcinoma Tissues after Sorafenib Treatment.
Li-Chun Lu, Yi-Hsuan Lee, +6 authors, Chih-Hung Hsu.
Liver Cancer, 2019 Apr 26; 8(2). PMID: 31019901    Free PMC article.
Timing of neoadjuvant immunotherapy in relation to surgery is crucial for outcome.
Jing Liu, Jake S O'Donnell, +4 authors, Michele W L Teng.
Oncoimmunology, 2019 May 10; 8(5). PMID: 31069141    Free PMC article.
Immune Checkpoint Blockade Enhances Shared Neoantigen-Induced T-cell Immunity Directed against Mutated Calreticulin in Myeloproliferative Neoplasms.
Cansu Cimen Bozkus, Vladimir Roudko, +4 authors, Nina Bhardwaj.
Cancer Discov, 2019 Jul 04; 9(9). PMID: 31266769    Free PMC article.
Immune-Checkpoint Protein VISTA Regulates Antitumor Immunity by Controlling Myeloid Cell-Mediated Inflammation and Immunosuppression.
Wenwen Xu, Juan Dong, +10 authors, Li Wang.
Cancer Immunol Res, 2019 Jul 26; 7(9). PMID: 31340983    Free PMC article.
Transdermal cold atmospheric plasma-mediated immune checkpoint blockade therapy.
Guojun Chen, Zhitong Chen, +6 authors, Zhen Gu.
Proc Natl Acad Sci U S A, 2020 Feb 08; 117(7). PMID: 32029590    Free PMC article.
Immunotherapy with immune checkpoint inhibitors in colorectal cancer: what is the future beyond deficient mismatch-repair tumours?
Nicolas Huyghe, Paméla Baldin, Marc Van den Eynde.
Gastroenterol Rep (Oxf), 2020 Feb 28; 8(1). PMID: 32104582    Free PMC article.
Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade.
Rohit R Jadhav, Se Jin Im, +7 authors, Jorg J Goronzy.
Proc Natl Acad Sci U S A, 2019 Jun 23; 116(28). PMID: 31227606    Free PMC article.
Highly Cited.
The Potential of the Cyclotide Scaffold for Drug Development.
Julio A Camarero, Maria Jose Campbell.
Biomedicines, 2019 Apr 24; 7(2). PMID: 31010257    Free PMC article.
Clinical significance of circulating soluble immune checkpoint proteins in sorafenib-treated patients with advanced hepatocellular carcinoma.
Minh Phuong Dong, Masaru Enomoto, +11 authors, Norifumi Kawada.
Sci Rep, 2020 Feb 27; 10(1). PMID: 32099055    Free PMC article.
Illuminating the Onco-GPCRome: Novel G protein-coupled receptor-driven oncocrine networks and targets for cancer immunotherapy.
Victoria Wu, Huwate Yeerna, +7 authors, J Silvio Gutkind.
J Biol Chem, 2019 Jun 07; 294(29). PMID: 31171722    Free PMC article.
Predicting clinical benefit of immunotherapy by antigenic or functional mutations affecting tumour immunogenicity.
Kwoneel Kim, Hong Sook Kim, +7 authors, Jung Kyoon Choi.
Nat Commun, 2020 Feb 23; 11(1). PMID: 32075964    Free PMC article.
Immune checkpoint modulation enhances HIV-1 antibody induction.
Todd Bradley, Masayuki Kuraoka, +27 authors, Barton F Haynes.
Nat Commun, 2020 Feb 23; 11(1). PMID: 32075963    Free PMC article.
PT-112 induces immunogenic cell death and synergizes with immune checkpoint blockers in mouse tumor models.
Takahiro Yamazaki, Aitziber Buqué, Tyler D Ames, Lorenzo Galluzzi.
Oncoimmunology, 2020 Mar 03; 9(1). PMID: 32117585    Free PMC article.
A tumor-targeted immune checkpoint blocker.
Yuhan Zhang, Changming Fang, +9 authors, Feng Wang.
Proc Natl Acad Sci U S A, 2019 Jul 25; 116(32). PMID: 31332018    Free PMC article.
Poor outcome with anti-programmed death-ligand 1 (PD-L1) antibody due to poor pharmacokinetic properties in PD-1/PD-L1 blockade-sensitive mouse models.
Taiki Kurino, Reiko Matsuda, +6 authors, Hiroto Hatakeyama.
J Immunother Cancer, 2020 Feb 12; 8(1). PMID: 32041818    Free PMC article.
Combination of chemotherapy and PD-1 blockade induces T cell responses to tumor non-mutated neoantigens.
Alessio Grimaldi, Ilenia Cammarata, +22 authors, Vincenzo Barnaba.
Commun Biol, 2020 Feb 27; 3(1). PMID: 32099064    Free PMC article.
Metabolic reprograming of anti-tumor immunity.
Madhusudhanan Sukumar, Rigel J Kishton, Nicholas P Restifo.
Curr Opin Immunol, 2017 Apr 17; 46. PMID: 28412583    Free PMC article.
CTLA-4: a moving target in immunotherapy.
Behzad Rowshanravan, Neil Halliday, David M Sansom.
Blood, 2017 Nov 10; 131(1). PMID: 29118008    Free PMC article.
Highly Cited. Review.
Lessons learned from the blockade of immune checkpoints in cancer immunotherapy.
Xiaolei Li, Changshun Shao, Yufang Shi, Weidong Han.
J Hematol Oncol, 2018 Feb 28; 11(1). PMID: 29482595    Free PMC article.
Highly Cited. Review.
IL17A Regulates Tumor Latency and Metastasis in Lung Adeno and Squamous SQ.2b and AD.1 Cancer.
Ran You, Francesco J DeMayo, +18 authors, Farrah Kheradmand.
Cancer Immunol Res, 2018 Apr 15; 6(6). PMID: 29653981    Free PMC article.
IFNγ: signalling, epigenetics and roles in immunity, metabolism, disease and cancer immunotherapy.
Lionel B Ivashkiv.
Nat Rev Immunol, 2018 Jun 21; 18(9). PMID: 29921905    Free PMC article.
Highly Cited. Review.
Acquired resistance to cancer immunotherapy.
Arianna Draghi, Christopher Aled Chamberlain, Andrew Furness, Marco Donia.
Semin Immunopathol, 2018 Jul 04; 41(1). PMID: 29968044
Immunological Mechanisms Responsible for Radiation-Induced Abscopal Effect.
María E Rodríguez-Ruiz, Claire Vanpouille-Box, +2 authors, Sandra Demaria.
Trends Immunol, 2018 Jul 14; 39(8). PMID: 30001871    Free PMC article.
Highly Cited. Review.
Emerging predictors of the response to the blockade of immune checkpoints in cancer therapy.
Xiaolei Li, Wenhui Song, +2 authors, Weidong Han.
Cell Mol Immunol, 2018 Jul 14; 16(1). PMID: 30002451    Free PMC article.
IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer.
Te-Chia Wu, Kangling Xu, +23 authors, A Karolina Palucka.
Cancer Res, 2018 Jul 18; 78(18). PMID: 30012670    Free PMC article.
Highly Cited.
PD-1+ stemlike CD8 T cells are resident in lymphoid tissues during persistent LCMV infection.
Se Jin Im, Bogumila T Konieczny, +2 authors, Rafi Ahmed.
Proc Natl Acad Sci U S A, 2020 Feb 09; 117(8). PMID: 32034098    Free PMC article.
Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3+ Regulatory T Cells (Tregs) in Human Cancers.
Anu Sharma, Sumit K Subudhi, +6 authors, Padmanee Sharma.
Clin Cancer Res, 2018 Jul 29; 25(4). PMID: 30054281    Free PMC article.
Highly Cited.
Immune Checkpoint Ligand PD-L1 Is Upregulated in Pulmonary Lymphangioleiomyomatosis.
Katharina Maisel, Mervyn J Merrilees, +12 authors, Vera P Krymskaya.
Am J Respir Cell Mol Biol, 2018 Aug 11; 59(6). PMID: 30095976    Free PMC article.
CIMT 2018: Pushing frontiers in cancer immunotherapy - Report on the 16th Annual Meeting of the Association for Cancer Immunotherapy.
Jan Beck, Matthias Birtel, +2 authors, Mustafa Diken.
Hum Vaccin Immunother, 2018 Aug 17; 14(12). PMID: 30111232    Free PMC article.
Principles of adoptive T cell therapy in cancer.
Özcan Met, Kasper Mølgaard Jensen, +2 authors, Inge Marie Svane.
Semin Immunopathol, 2018 Sep 07; 41(1). PMID: 30187086
Murine pre-B-cell ALL induces T-cell dysfunction not fully reversed by introduction of a chimeric antigen receptor.
Haiying Qin, Kazusa Ishii, +8 authors, Terry J Fry.
Blood, 2018 Sep 14; 132(18). PMID: 30209120    Free PMC article.
Potentially functional genetic variants in the complement-related immunity gene-set are associated with non-small cell lung cancer survival.
Danwen Qian, Hongliang Liu, +8 authors, Qingyi Wei.
Int J Cancer, 2018 Sep 28; 144(8). PMID: 30259978    Free PMC article.
PD-L1 Mediates Dysfunction in Activated PD-1+ NK Cells in Head and Neck Cancer Patients.
Fernando Concha-Benavente, Benjamin Kansy, +3 authors, Robert L Ferris.
Cancer Immunol Res, 2018 Oct 05; 6(12). PMID: 30282672    Free PMC article.
Highly Cited.
High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy.
Matthew M Gubin, Ekaterina Esaulova, +16 authors, Maxim N Artyomov.
Cell, 2018 Oct 23; 175(4). PMID: 30343900    Free PMC article.
Highly Cited.
The immunologic constant of rejection classification refines the prognostic value of conventional prognostic signatures in breast cancer.
François Bertucci, Pascal Finetti, +8 authors, Davide Bedognetti.
Br J Cancer, 2018 Oct 26; 119(11). PMID: 30353048    Free PMC article.
T-cell trafficking plays an essential role in tumor immunity.
Daniel J Aires, Masaru Yoshida, +10 authors, Thomas S Kupper.
Lab Invest, 2018 Oct 26; 99(1). PMID: 30353131    Free PMC article.
A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade.
Livnat Jerby-Arnon, Parin Shah, +49 authors, Aviv Regev.
Cell, 2018 Nov 06; 175(4). PMID: 30388455    Free PMC article.
Highly Cited.
Cytokines in clinical cancer immunotherapy.
Pedro Berraondo, Miguel F Sanmamed, +7 authors, Ignacio Melero.
Br J Cancer, 2018 Nov 11; 120(1). PMID: 30413827    Free PMC article.
Highly Cited. Review.
E3611-A Randomized Phase II Study of Ipilimumab at 3 or 10 mg/kg Alone or in Combination with High-Dose Interferon-α2b in Advanced Melanoma.
Ahmad A Tarhini, Sandra J Lee, +10 authors, John M Kirkwood.
Clin Cancer Res, 2018 Nov 14; 25(2). PMID: 30420448    Free PMC article.
Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells.
Pascale André, Caroline Denis, +27 authors, Eric Vivier.
Cell, 2018 Dec 07; 175(7). PMID: 30503213    Free PMC article.
Highly Cited. Review.
Dynamics of Tumor and Immune Responses during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer.
Valsamo Anagnostou, Patrick M Forde, +33 authors, Victor E Velculescu.
Cancer Res, 2018 Dec 14; 79(6). PMID: 30541742    Free PMC article.
1-Pyrroline-5-carboxylate released by prostate Cancer cell inhibit T cell proliferation and function by targeting SHP1/cytochrome c oxidoreductase/ROS Axis.
Yutao Yan, Lei Chang, +8 authors, Yonglian Guo.
J Immunother Cancer, 2018 Dec 14; 6(1). PMID: 30545412    Free PMC article.
Dynamic metrics-based biomarkers to predict responders to anti-PD-1 immunotherapy.
Can Liu, Hua He, +2 authors, Yanguang Cao.
Br J Cancer, 2018 Dec 28; 120(3). PMID: 30587849    Free PMC article.
A CD40 Agonist and PD-1 Antagonist Antibody Reprogram the Microenvironment of Nonimmunogenic Tumors to Allow T-cell-Mediated Anticancer Activity.
Hayley S Ma, Bibhav Poudel, +9 authors, Elizabeth M Jaffee.
Cancer Immunol Res, 2019 Jan 16; 7(3). PMID: 30642833    Free PMC article.
Engineering Nanoparticles for Targeted Remodeling of the Tumor Microenvironment to Improve Cancer Immunotherapy.
Shan Gao, Dongjuan Yang, +6 authors, Kai Shi.
Theranostics, 2019 Jan 22; 9(1). PMID: 30662558    Free PMC article.
Highly Cited. Review.
Tumor mutational burden standardization initiatives: Recommendations for consistent tumor mutational burden assessment in clinical samples to guide immunotherapy treatment decisions.
Albrecht Stenzinger, Jeffrey D Allen, +4 authors, Manfred Dietel.
Genes Chromosomes Cancer, 2019 Jan 22; 58(8). PMID: 30664300    Free PMC article.
Highly Cited. Review.
Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy.
Daniel Shae, Kyle W Becker, +8 authors, John T Wilson.
Nat Nanotechnol, 2019 Jan 22; 14(3). PMID: 30664751    Free PMC article.
Highly Cited.
A Blazing Landscape: Neuroinflammation Shapes Brain Metastasis.
Hila Doron, Tobias Pukrop, Neta Erez.
Cancer Res, 2019 Jan 27; 79(3). PMID: 30679177    Free PMC article.
Blockade of the PD-1 axis alone is not sufficient to activate HIV-1 virion production from CD4+ T cells of individuals on suppressive ART.
John K Bui, Joshua C Cyktor, +3 authors, John W Mellors.
PLoS One, 2019 Jan 27; 14(1). PMID: 30682108    Free PMC article.
Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas.
Keisuke Kataoka, Hiroaki Miyoshi, +35 authors, Seishi Ogawa.
Leukemia, 2019 Jan 27; 33(7). PMID: 30683910    Free PMC article.
Demarcated thresholds of tumor-specific CD8 T cells elicited by MCMV-based vaccine vectors provide robust correlates of protection.
Elham Beyranvand Nejad, Robert B Ratts, +6 authors, Ramon Arens.
J Immunother Cancer, 2019 Feb 02; 7(1). PMID: 30704520    Free PMC article.
Highly Cited.
Clinical outcomes of advanced stage cancer patients treated with sequential immunotherapy in phase 1 clinical trials.
Dylan J Martini, Yuan Liu, +19 authors, Mehmet Asim Bilen.
Invest New Drugs, 2019 Feb 07; 37(6). PMID: 30725388    Free PMC article.
Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer.
Triparna Sen, B Leticia Rodriguez, +16 authors, Lauren A Byers.
Cancer Discov, 2019 Feb 20; 9(5). PMID: 30777870    Free PMC article.
Highly Cited.
PD-1-siRNA delivered by attenuated Salmonella enhances the antimelanoma effect of pimozide.
Tiesuo Zhao, Tian Wei, +6 authors, Zhiwei Feng.
Cell Death Dis, 2019 Feb 20; 10(3). PMID: 30778049    Free PMC article.
Risk of Pneumonitis and Pneumonia Associated With Immune Checkpoint Inhibitors for Solid Tumors: A Systematic Review and Meta-Analysis.
Qiang Su, Emily C Zhu, +4 authors, Zu-Hua Gao.
Front Immunol, 2019 Feb 20; 10. PMID: 30778352    Free PMC article.
Systematic Review.
Mutations in DNA repair genes are associated with increased neoantigen burden and a distinct immunophenotype in lung squamous cell carcinoma.
Young Kwang Chae, Jonathan F Anker, +5 authors, Jeffrey H Chuang.
Sci Rep, 2019 Mar 03; 9(1). PMID: 30824826    Free PMC article.
Exceptional response and multisystem autoimmune-like toxicities associated with the same T cell clone in a patient with uveal melanoma treated with immune checkpoint inhibitors.
Suthee Rapisuwon, Benjamin Izar, +9 authors, Michael B Atkins.
J Immunother Cancer, 2019 Mar 06; 7(1). PMID: 30832716    Free PMC article.
Genomic correlates of response to immune checkpoint blockade.
Tanya E Keenan, Kelly P Burke, Eliezer M Van Allen.
Nat Med, 2019 Mar 08; 25(3). PMID: 30842677    Free PMC article.
Highly Cited. Review.
Collagen density regulates the activity of tumor-infiltrating T cells.
Dorota E Kuczek, Anne Mette H Larsen, +12 authors, Daniel H Madsen.
J Immunother Cancer, 2019 Mar 15; 7(1). PMID: 30867051    Free PMC article.
Cocultures of human colorectal tumor spheroids with immune cells reveal the therapeutic potential of MICA/B and NKG2A targeting for cancer treatment.
Tristan Courau, Julie Bonnereau, +8 authors, Lionel Le Bourhis.
J Immunother Cancer, 2019 Mar 16; 7(1). PMID: 30871626    Free PMC article.
PD-1 and PD-L1 in cancer immunotherapy: clinical implications and future considerations.
Yongshuai Jiang, Ming Chen, Hong Nie, Yuanyang Yuan.
Hum Vaccin Immunother, 2019 Mar 20; 15(5). PMID: 30888929    Free PMC article.
Innate lymphoid cells: A potential link between microbiota and immune responses against cancer.
Santosh K Panda, Marco Colonna.
Semin Immunol, 2019 Mar 25; 41. PMID: 30902413    Free PMC article.
Specialized dendritic cells induce tumor-promoting IL-10+IL-17+ FoxP3neg regulatory CD4+ T cells in pancreatic carcinoma.
Rocky M Barilla, Brian Diskin, +27 authors, George Miller.
Nat Commun, 2019 Mar 31; 10(1). PMID: 30926808    Free PMC article.
Dual functional immunostimulatory polymeric prodrug carrier with pendent indoximod for enhanced cancer immunochemotherapy.
Zhuoya Wan, Jingjing Sun, +11 authors, Song Li.
Acta Biomater, 2019 Apr 02; 90. PMID: 30930305    Free PMC article.
CD91 on dendritic cells governs immunosurveillance of nascent, emerging tumors.
Abigail L Sedlacek, Theodore P Younker, +4 authors, Robert J Binder.
JCI Insight, 2019 Apr 05; 4(7). PMID: 30944251    Free PMC article.
Targeted antibody and cytokine cancer immunotherapies through collagen affinity.
Jun Ishihara, Ako Ishihara, +15 authors, Jeffrey A Hubbell.
Sci Transl Med, 2019 Apr 12; 11(487). PMID: 30971453    Free PMC article.
Highly Cited.
Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species.
Rapolas Zilionis, Camilla Engblom, +15 authors, Allon M Klein.
Immunity, 2019 Apr 14; 50(5). PMID: 30979687    Free PMC article.
Highly Cited.
Immunogenic neoantigens derived from gene fusions stimulate T cell responses.
Wei Yang, Ken-Wing Lee, +31 authors, Luc G T Morris.
Nat Med, 2019 Apr 24; 25(5). PMID: 31011208    Free PMC article.
Highly Cited.
Bispecific CD3-HAC carried by E1A-engineered mesenchymal stromal cells against metastatic breast cancer by blocking PD-L1 and activating T cells.
Yuanyuan Yang, Xiaolong Zhang, +11 authors, Dongsheng Xiong.
J Hematol Oncol, 2019 Apr 27; 12(1). PMID: 31023384    Free PMC article.
Costimulation Induces CD4 T Cell Antitumor Immunity via an Innate-like Mechanism.
Crystal Morales Del Valle, Joseph R Maxwell, +5 authors, Anthony T Vella.
Cell Rep, 2019 May 03; 27(5). PMID: 31042471    Free PMC article.
Recurrent pseudogout after therapy with immune checkpoint inhibitors: a case report with immunoprofiling of synovial fluid at each flare.
Sang T Kim, Mohamad Bittar, +4 authors, Maria E Suarez-Almazor.
J Immunother Cancer, 2019 May 16; 7(1). PMID: 31088575    Free PMC article.
The local immune landscape determines tumor PD-L1 heterogeneity and sensitivity to therapy.
Yuan Wei, Qiyi Zhao, +9 authors, Dong-Ming Kuang.
J Clin Invest, 2019 May 22; 129(8). PMID: 31112529    Free PMC article.
Highly Cited.
Immune cell therapy for hepatocellular carcinoma.
Eishiro Mizukoshi, Shuichi Kaneko.
J Hematol Oncol, 2019 May 31; 12(1). PMID: 31142330    Free PMC article.
Highly Cited. Review.
A novel model of controlling PD-L1 expression in ALK+ anaplastic large cell lymphoma revealed by CRISPR screening.
Jing-Ping Zhang, Zhihui Song, +10 authors, Yibin Yang.
Blood, 2019 Jun 04; 134(2). PMID: 31151983    Free PMC article.
Enforcing the checkpoints: harnessing T-cell exhaustion for therapy of T1D.
Peter S Linsley, S Alice Long.
Curr Opin Endocrinol Diabetes Obes, 2019 Jun 04; 26(4). PMID: 31157632    Free PMC article.
Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade.
Anna Morena D'Alise, Guido Leoni, +17 authors, Elisa Scarselli.
Nat Commun, 2019 Jun 21; 10(1). PMID: 31217437    Free PMC article.
NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices.
Hongqian Chu, Jian Zhao, +2 authors, Lele Li.
Nat Commun, 2019 Jun 30; 10(1). PMID: 31253798    Free PMC article.
Photoacoustic imaging as a tool to probe the tumour microenvironment.
Emma Brown, Joanna Brunker, Sarah E Bohndiek.
Dis Model Mech, 2019 Jul 25; 12(7). PMID: 31337635    Free PMC article.
Deep single-cell RNA sequencing data of individual T cells from treatment-naïve colorectal cancer patients.
Yuanyuan Zhang, Liangtao Zheng, +3 authors, Zemin Zhang.
Sci Data, 2019 Jul 26; 6(1). PMID: 31341169    Free PMC article.
Clonal replacement of tumor-specific T cells following PD-1 blockade.
Kathryn E Yost, Ansuman T Satpathy, +13 authors, Howard Y Chang.
Nat Med, 2019 Jul 31; 25(8). PMID: 31359002    Free PMC article.
Highly Cited.
Dual CTLA-4 and PD-L1 Blockade Inhibits Tumor Growth and Liver Metastasis in a Highly Aggressive Orthotopic Mouse Model of Colon Cancer.
E Fiegle, D Doleschel, +5 authors, W Lederle.
Neoplasia, 2019 Aug 15; 21(9). PMID: 31412307    Free PMC article.
Syringeable immunotherapeutic nanogel reshapes tumor microenvironment and prevents tumor metastasis and recurrence.
Chanyoung Song, Hathaichanok Phuengkham, +13 authors, Yong Taik Lim.
Nat Commun, 2019 Aug 23; 10(1). PMID: 31431623    Free PMC article.
DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load.
Hyunchul Jung, Hong Sook Kim, +7 authors, Jung Kyoon Choi.
Nat Commun, 2019 Sep 21; 10(1). PMID: 31537801    Free PMC article.
CD137 ligand feedback upregulates PD-L1 expression on lung cancer via T cell production of IFN-γ.
Helin Wang, Zhuohong Yan, +7 authors, Shucai Zhang.
Thorac Cancer, 2019 Oct 19; 10(12). PMID: 31625289    Free PMC article.
Checkpoint Blockade Strategies in the Treatment of Breast Cancer: Where We Are and Where We Are Heading.
Jeremy Force, Jorge Henrique Santos Leal, Heather L McArthur.
Curr Treat Options Oncol, 2019 Mar 30; 20(4). PMID: 30923913
Anti-PD-1 and Novel Combinations in the Treatment of Melanoma-An Update.
Frank Friedrich Gellrich, Marc Schmitz, Stefan Beissert, Friedegund Meier.
J Clin Med, 2020 Jan 18; 9(1). PMID: 31947592    Free PMC article.
Immunosurveillance and Immunoediting of Lung Cancer: Current Perspectives and Challenges.
Kei Kunimasa, Taichiro Goto.
Int J Mol Sci, 2020 Jan 23; 21(2). PMID: 31963413    Free PMC article.
Immune Modulation by Telomerase-Specific Oncolytic Adenovirus Synergistically Enhances Antitumor Efficacy with Anti-PD1 Antibody.
Nobuhiko Kanaya, Shinji Kuroda, +13 authors, Toshiyoshi Fujiwara.
Mol Ther, 2020 Jan 29; 28(3). PMID: 31991110    Free PMC article.
Cancer Vaccines: Steering T Cells Down the Right Path to Eradicate Tumors.
Patrick A Ott, Catherine J Wu.
Cancer Discov, 2019 Mar 14; 9(4). PMID: 30862723    Free PMC article.
Another layer of immune complication in glioblastoma: inducible co-stimulator and its ligand.
Masaki Terabe, Mark R Gilbert.
Neuro Oncol, 2020 Jan 08; 22(3). PMID: 31909413    Free PMC article.
T-Cell Immunotherapies Targeting Histocompatibility and Tumor Antigens in Hematological Malignancies.
Valérie Janelle, Caroline Rulleau, +2 authors, Jean-Sébastien Delisle.
Front Immunol, 2020 Mar 11; 11. PMID: 32153583    Free PMC article.
Re-defining T-Cell Exhaustion: Subset, Function, and Regulation.
Se Jin Im, Sang-Jun Ha.
Immune Netw, 2020 Mar 12; 20(1). PMID: 32158590    Free PMC article.
Valproic acid attenuates CCR2-dependent tumor infiltration of monocytic myeloid-derived suppressor cells, limiting tumor progression.
Zhiqi Xie, Tamami Ikegami, +2 authors, Masashi Tachibana.
Oncoimmunology, 2020 Mar 12; 9(1). PMID: 32158627    Free PMC article.
Therapeutic targeting of trained immunity.
Willem J M Mulder, Jordi Ochando, +2 authors, Mihai G Netea.
Nat Rev Drug Discov, 2019 Apr 11; 18(7). PMID: 30967658    Free PMC article.
Highly Cited. Review.
Multi-Dimensional Flow Cytometry Analyses Reveal a Dichotomous Role for Nitric Oxide in Melanoma Patients Receiving Immunotherapy.
Saurabh K Garg, Matthew J Ott, +12 authors, Joseph Markowitz.
Front Immunol, 2020 Mar 13; 11. PMID: 32161584    Free PMC article.
PLCε1 suppresses tumor growth by regulating murine T cell mobilization.
M Strazza, K Adam, +2 authors, A Mor.
Clin Exp Immunol, 2019 Dec 24; 200(1). PMID: 31867717    Free PMC article.
Development of a protein-based system for transient epigenetic repression of immune checkpoint molecule and enhancement of antitumour activity of natural killer cells.
Yoichi Teratake, Tomoki Takashina, +3 authors, Yukihito Ishizaka.
Br J Cancer, 2020 Jan 22; 122(6). PMID: 31959920    Free PMC article.
An engineered oncolytic virus expressing PD-L1 inhibitors activates tumor neoantigen-specific T cell responses.
Guan Wang, Xi Kang, +5 authors, Si-Yi Chen.
Nat Commun, 2020 Mar 15; 11(1). PMID: 32170083    Free PMC article.
Identification of immune-enhanced molecular subtype associated with BRCA1 mutations, immune checkpoints and clinical outcome in ovarian carcinoma.
Mingjun Zheng, Yuexin Hu, +7 authors, Bei Lin.
J Cell Mol Med, 2020 Jan 30; 24(5). PMID: 31995855    Free PMC article.
A liquid biopsy to detect multidrug resistance and disease burden in multiple myeloma.
Sabna Rajeev Krishnan, Gabriele De Rubis, +3 authors, Mary Bebawy.
Blood Cancer J, 2020 Mar 15; 10(3). PMID: 32170169    Free PMC article.
Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma.
Lihong Wang-Bishop, Mohamed Wehbe, +7 authors, John T Wilson.
J Immunother Cancer, 2020 Mar 15; 8(1). PMID: 32169869    Free PMC article.
Pre-existing inflammatory immune microenvironment predicts the clinical response of vulvar high-grade squamous intraepithelial lesions to therapeutic HPV16 vaccination.
Ziena Abdulrahman, Noel de Miranda, +5 authors, Sjoerd H van der Burg.
J Immunother Cancer, 2020 Mar 15; 8(1). PMID: 32169871    Free PMC article.
Compound kushen injection relieves tumor-associated macrophage-mediated immunosuppression through TNFR1 and sensitizes hepatocellular carcinoma to sorafenib.
Yang Yang, Mayu Sun, +10 authors, Hui Wang.
J Immunother Cancer, 2020 Mar 18; 8(1). PMID: 32179631    Free PMC article.
Characteristics of Tumor-Infiltrating Lymphocytes Prior to and During Immune Checkpoint Inhibitor Therapy.
Ioana Plesca, Antje Tunger, +6 authors, Marc Schmitz.
Front Immunol, 2020 Mar 21; 11. PMID: 32194568    Free PMC article.
The Combination Options and Predictive Biomarkers of PD-1/PD-L1 Inhibitors in Esophageal Cancer.
Hui Yang, Kunlun Wang, +4 authors, Ling Yuan.
Front Oncol, 2020 Mar 21; 10. PMID: 32195194    Free PMC article.
IL-33 in Tumor Immunity: Nothing to Sneeze At.
Donye Dominguez, Yi Zhang, Bin Zhang.
Crit Rev Immunol, 2018 Jan 01; 38(6). PMID: 31002600    Free PMC article.
Novel and emerging therapies for B cell lymphoma.
Sabarish Ayyappan, Kami Maddocks.
J Hematol Oncol, 2019 Jul 28; 12(1). PMID: 31345247    Free PMC article.
High-Dose Dexamethasone Manipulates the Tumor Microenvironment and Internal Metabolic Pathways in Anti-Tumor Progression.
Lei Xu, Hua Xia, +6 authors, Yajun Xie.
Int J Mol Sci, 2020 Mar 12; 21(5). PMID: 32156004    Free PMC article.
Phase 2 study of pembrolizumab in patients with advanced rare cancers.
Aung Naing, Funda Meric-Bernstam, +37 authors, Mouhammed Amir Habra.
J Immunother Cancer, 2020 Mar 20; 8(1). PMID: 32188704    Free PMC article.
Closed system RT-qPCR as a potential companion diagnostic test for immunotherapy outcome in metastatic melanoma.
Swati Gupta, Leena McCann, +9 authors, David L Rimm.
J Immunother Cancer, 2019 Sep 20; 7(1). PMID: 31533832    Free PMC article.
Transcriptional profiling of tumor associated macrophages in human renal cell carcinoma reveals significant heterogeneity and opportunity for immunomodulation.
Thomas R Nirschl, Margueritta El Asmar, +7 authors, Jelani C Zarif.
Am J Clin Exp Urol, 2020 Mar 27; 8(1). PMID: 32211454    Free PMC article.
What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans? Reevaluating the Potential of Mouse Models for the Human Immune System.
Stephen C Jameson, David Masopust.
Cold Spring Harb Perspect Biol, 2017 Mar 30; 10(4). PMID: 28348039    Free PMC article.
CD73 Blockade Promotes Dendritic Cell Infiltration of Irradiated Tumors and Tumor Rejection.
Erik Wennerberg, Sheila Spada, +8 authors, Sandra Demaria.
Cancer Immunol Res, 2020 Feb 13; 8(4). PMID: 32047024    Free PMC article.
Therapeutic Cancer Vaccine and Combinations With Antiangiogenic Therapies and Immune Checkpoint Blockade.
Alice Mougel, Magali Terme, Corinne Tanchot.
Front Immunol, 2019 Mar 30; 10. PMID: 30923527    Free PMC article.
Highly Cited. Review.
Immunostimulatory CpG on Carbon Nanotubes Selectively Inhibits Migration of Brain Tumor Cells.
Darya Alizadeh, Ethan E White, +4 authors, Jacob M Berlin.
Bioconjug Chem, 2018 Mar 13; 29(5). PMID: 29526082    Free PMC article.
Combining Immune Checkpoint Inhibitors with Anti-Angiogenic Agents.
Paola Ciciola, Priscilla Cascetta, +2 authors, Roberto Bianco.
J Clin Med, 2020 Mar 07; 9(3). PMID: 32138216    Free PMC article.
Dendritic Cells in Anticancer Vaccination: Rationale for Ex Vivo Loading or In Vivo Targeting.
Alexey V Baldin, Lyudmila V Savvateeva, Alexandr V Bazhin, Andrey A Zamyatnin.
Cancers (Basel), 2020 Mar 11; 12(3). PMID: 32150821    Free PMC article.
Epitope-directed antibody selection by site-specific photocrosslinking.
Longxin Chen, Chaoyang Zhu, +10 authors, Feng Wang.
Sci Adv, 2020 Apr 10; 6(14). PMID: 32270046    Free PMC article.
TLR3 Activation of Intratumoral CD103+ Dendritic Cells Modifies the Tumor Infiltrate Conferring Anti-tumor Immunity.
Emiliano Roselli, Paula Araya, +6 authors, Mariana Maccioni.
Front Immunol, 2019 Apr 06; 10. PMID: 30949170    Free PMC article.
Immunotherapy, Inflammation and Colorectal Cancer.
Charles Robert Lichtenstern, Rachael Katie Ngu, Shabnam Shalapour, Michael Karin.
Cells, 2020 Mar 08; 9(3). PMID: 32143413    Free PMC article.
The Galectin Family as Molecular Targets: Hopes for Defeating Pancreatic Cancer.
Noemí Manero-Rupérez, Neus Martínez-Bosch, +2 authors, Pilar Navarro.
Cells, 2020 Mar 15; 9(3). PMID: 32168866    Free PMC article.
The Inhibitory Mechanisms of Tumor PD-L1 Expression by Natural Bioactive Gallic Acid in Non-Small-Cell Lung Cancer (NSCLC) Cells.
Dong Young Kang, Nipin Sp, +7 authors, Young Mok Yang.
Cancers (Basel), 2020 Mar 25; 12(3). PMID: 32204508    Free PMC article.
High-salt diet inhibits tumour growth in mice via regulating myeloid-derived suppressor cell differentiation.
Wei He, Jinzhi Xu, +6 authors, Lei Dong.
Nat Commun, 2020 Apr 09; 11(1). PMID: 32265505    Free PMC article.
NK Cell Dysfunction and Checkpoint Immunotherapy.
Jiacheng Bi, Zhigang Tian.
Front Immunol, 2019 Sep 26; 10. PMID: 31552017    Free PMC article.
New Approaches on Cancer Immunotherapy.
Jong-Ho Cha, Li-Chuan Chan, Min Sup Song, Mien-Chie Hung.
Cold Spring Harb Perspect Med, 2019 Oct 17; 10(8). PMID: 31615865    Free PMC article.
Targeting the Immunomodulatory CD73/Adenosine System to Improve the Therapeutic Gain of Radiotherapy.
Simone de Leve, Florian Wirsdörfer, Verena Jendrossek.
Front Immunol, 2019 Apr 27; 10. PMID: 31024543    Free PMC article.
Immune Conversion of Tumor Microenvironment by Oncolytic Viruses: The Protoparvovirus H-1PV Case Study.
Antonio Marchini, Laurent Daeffler, +2 authors, Jean Rommelaere.
Front Immunol, 2019 Aug 24; 10. PMID: 31440242    Free PMC article.
Pembrolizumab monotherapy versus chemotherapy for treatment of advanced urothelial carcinoma with disease progression during or following platinum-containing chemotherapy. A Cochrane Rapid Review.
Vikram Narayan, Andreas Kahlmeyer, +8 authors, Frank Kunath.
Cochrane Database Syst Rev, 2018 Jul 24; 7. PMID: 30036453    Free PMC article.
Systematic Review.
Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health.
Feixiong Cheng, Han Liang, +2 authors, Ruth Nussinov.
Pharmacol Rev, 2018 Dec 14; 71(1). PMID: 30545954    Free PMC article.
Level of neo-epitope predecessor and mutation type determine T cell activation of MHC binding peptides.
Hanan Besser, Sharon Yunger, +2 authors, Yoram Louzoun.
J Immunother Cancer, 2019 May 24; 7(1). PMID: 31118084    Free PMC article.
Targeting and exploitation of tumor-associated neutrophils to enhance immunotherapy and drug delivery for cancer treatment.
Yuting Zhang, Liu Guoqiang, Miaomiao Sun, Xin Lu.
Cancer Biol Med, 2020 Apr 17; 17(1). PMID: 32296575    Free PMC article.
PD-L1 and PD1 expression in post-transplantation lymphoproliferative disease (PTLD) of childhood and adolescence: An inter- and intra-individual descriptive study covering the whole spectrum of PTLD categories.
Ana-Iris Schiefer, Elisabeth Salzer, +10 authors, Andishe Attarbaschi.
Cancer Med, 2019 Jul 04; 8(10). PMID: 31269329    Free PMC article.
T Cell Dysfunction in Cancer Immunity and Immunotherapy.
Anliang Xia, Yan Zhang, +2 authors, Xiao-Jie Lu.
Front Immunol, 2019 Aug 06; 10. PMID: 31379886    Free PMC article.
Highly Cited. Review.
Cytotoxic Chemotherapy as an Immune Stimulus: A Molecular Perspective on Turning Up the Immunological Heat on Cancer.
James W Opzoomer, Dominika Sosnowska, +2 authors, James N Arnold.
Front Immunol, 2019 Aug 06; 10. PMID: 31379850    Free PMC article.
Regulatory Interactions Between Neutrophils, Tumor Cells and T Cells.
Hans-Heinrich Oberg, Daniela Wesch, Shirin Kalyan, Dieter Kabelitz.
Front Immunol, 2019 Aug 06; 10. PMID: 31379875    Free PMC article.
Antibodies specific for disease-associated antigens (DAA) expressed in non-malignant diseases reveal potential new tumor-associated antigens (TAA) for immunotherapy or immunoprevention.
Camille Jacqueline, Olivera J Finn.
Semin Immunol, 2020 Apr 11; 47. PMID: 32273212    Free PMC article.
Magnetic targeted near-infrared II PA/MR imaging guided photothermal therapy to trigger cancer immunotherapy.
Qinrui Fu, Zhi Li, +6 authors, Jibin Song.
Theranostics, 2020 Apr 21; 10(11). PMID: 32308764    Free PMC article.
Hypomethylating agent alters the immune microenvironment in acute myeloid leukaemia (AML) and enhances the immunogenicity of a dendritic cell/AML vaccine.
Myrna R Nahas, Dina Stroopinsky, +18 authors, David Avigan.
Br J Haematol, 2019 Mar 05; 185(4). PMID: 30828801    Free PMC article.
TNF‑α‑mediated epithelial‑to‑mesenchymal transition regulates expression of immune checkpoint molecules in hepatocellular carcinoma.
Ritu Shrestha, Kim R Bridle, Darrell H G Crawford, Aparna Jayachandran.
Mol Med Rep, 2020 Apr 23; 21(4). PMID: 32319631    Free PMC article.
Immune profiling of human tumors identifies CD73 as a combinatorial target in glioblastoma.
Sangeeta Goswami, Thomas Walle, +17 authors, Padmanee Sharma.
Nat Med, 2019 Dec 25; 26(1). PMID: 31873309    Free PMC article.
Ushering in Integrated T Cell Repertoire Profiling in Cancer.
Ning Jiang, Alexandra A Schonnesen, Ke-Yue Ma.
Trends Cancer, 2019 Feb 14; 5(2). PMID: 30755308    Free PMC article.
Clinicopathological Features of Programmed Cell Death-ligand 1 Expression in Patients with Oral Squamous Cell Carcinoma.
Yong-Xin Cui, Xian-Shuang Su.
Open Med (Wars), 2020 Apr 28; 15. PMID: 32337367    Free PMC article.
Impact of exercise on the immune system and outcomes in hematologic malignancies.
Andrea Sitlinger, Danielle M Brander, David B Bartlett.
Blood Adv, 2020 Apr 29; 4(8). PMID: 32343800    Free PMC article.
Pembrolizumab for the Treatment of Hepatocellular Carcinoma.
Masatoshi Kudo.
Liver Cancer, 2019 Jun 14; 8(3). PMID: 31192152    Free PMC article.
Comprehensive Analysis of the Expression and Prognosis for TDO2 in Breast Cancer.
Qiang Liu, Jie Zhai, +4 authors, Jing Wang.
Mol Ther Oncolytics, 2020 Apr 30; 17. PMID: 32346606    Free PMC article.
Expression of Programmed Death Ligand 1 (PD-L1) in Posttreatment Primary Inflammatory Breast Cancers and Clinical Implications.
Jing He, Lei Huo, +6 authors, Yun Gong.
Am J Clin Pathol, 2018 Feb 10; 149(3). PMID: 29425258    Free PMC article.
HERA-GITRL activates T cells and promotes anti-tumor efficacy independent of FcγR-binding functionality.
David M Richards, Viola Marschall, +10 authors, Meinolf Thiemann.
J Immunother Cancer, 2019 Jul 22; 7(1). PMID: 31324216    Free PMC article.
PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma.
Xian-De Liu, Wen Kong, +15 authors, Eric Jonasch.
Nat Commun, 2020 May 03; 11(1). PMID: 32358509    Free PMC article.
Late-differentiated effector neoantigen-specific CD8+ T cells are enriched in peripheral blood of non-small cell lung carcinoma patients responding to atezolizumab treatment.
Michael Fehlings, Suchit Jhunjhunwala, +10 authors, Mahesh Yadav.
J Immunother Cancer, 2019 Sep 13; 7(1). PMID: 31511069    Free PMC article.
Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies.
Stefanie R Mullins, John P Vasilakos, +16 authors, Robert W Wilkinson.
J Immunother Cancer, 2019 Sep 13; 7(1). PMID: 31511088    Free PMC article.
Defining trained immunity and its role in health and disease.
Mihai G Netea, Jorge Domínguez-Andrés, +14 authors, Eicke Latz.
Nat Rev Immunol, 2020 Mar 07; 20(6). PMID: 32132681    Free PMC article.
Biomarkers of immune checkpoint inhibitor efficacy in cancer.
D E Meyers, S Banerji.
Curr Oncol, 2020 May 06; 27(Suppl 2). PMID: 32368180    Free PMC article.
Phenotypic screening using large-scale genomic libraries to identify drug targets for the treatment of cancer.
Mitsuo Sato.
Oncol Lett, 2020 May 12; 19(6). PMID: 32391087    Free PMC article.
NK cells mediate clearance of CD8+ T cell-resistant tumors in response to STING agonists.
Christopher J Nicolai, Natalie Wolf, +5 authors, David H Raulet.
Sci Immunol, 2020 Mar 22; 5(45). PMID: 32198222    Free PMC article.
Therapeutic ISCOMATRIX™ adjuvant vaccine elicits effective anti-tumor immunity in the TRAMP-C1 mouse model of prostate cancer.
Adele M Barr, Anabel Silva, +3 authors, Adriana Baz Morelli.
Cancer Immunol Immunother, 2020 May 11; 69(10). PMID: 32388678    Free PMC article.
A New Era in Systemic Therapy for Hepatocellular Carcinoma: Atezolizumab plus Bevacizumab Combination Therapy.
Masatoshi Kudo.
Liver Cancer, 2020 May 14; 9(2). PMID: 32399427    Free PMC article.
Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing.
Timour Baslan, Jude Kendall, +22 authors, James Hicks.
Elife, 2020 May 14; 9. PMID: 32401198    Free PMC article.
Hyperprogression and impact of tumor growth kinetics after PD1/PDL1 inhibition in head and neck squamous cell carcinoma.
Andy Karabajakian, Thibaut Garrivier, +8 authors, Jérôme Fayette.
Oncotarget, 2020 May 15; 11(18). PMID: 32405337    Free PMC article.
High-affinity mutant Interleukin-13 targeted CAR T cells enhance delivery of clickable biodegradable fluorescent nanoparticles to glioblastoma.
Gloria B Kim, Virginia Aragon-Sanabria, +8 authors, Cheng Dong.
Bioact Mater, 2020 May 15; 5(3). PMID: 32405577    Free PMC article.
Adverse Events Following Cancer Immunotherapy: Obstacles and Opportunities.
Kristen E Pauken, Michael Dougan, +2 authors, Arlene H Sharpe.
Trends Immunol, 2019 May 06; 40(6). PMID: 31053497    Free PMC article.
Highly Cited. Review.
Inhibition of the NKp44-PCNA Immune Checkpoint Using a mAb to PCNA.
Kiran Kundu, Susmita Ghosh, +11 authors, Angel Porgador.
Cancer Immunol Res, 2019 Jun 06; 7(7). PMID: 31164357    Free PMC article.
Anti-OX40 Antibody Directly Enhances The Function of Tumor-Reactive CD8+ T Cells and Synergizes with PI3Kβ Inhibition in PTEN Loss Melanoma.
Weiyi Peng, Leila J Williams, +17 authors, Patrick Hwu.
Clin Cancer Res, 2019 Aug 03; 25(21). PMID: 31371342    Free PMC article.
Recent Advances in Immunotherapy for Hepatocellular Carcinoma.
Shigeharu Nakano, Yuji Eso, +3 authors, Hiroshi Seno.
Cancers (Basel), 2020 Mar 29; 12(4). PMID: 32218257    Free PMC article.
Platelet-Leukocyte Interplay in Cancer Development and Progression.
Dagmar Stoiber, Alice Assinger.
Cells, 2020 Apr 05; 9(4). PMID: 32244723    Free PMC article.
Natural Killer Cells: Tumor Surveillance and Signaling.
Lizeth G Meza Guzman, Narelle Keating, Sandra E Nicholson.
Cancers (Basel), 2020 Apr 16; 12(4). PMID: 32290478    Free PMC article.
Macrophage checkpoint blockade: results from initial clinical trials, binding analyses, and CD47-SIRPα structure-function.
AbdelAziz R Jalil, Jason C Andrechak, Dennis E Discher.
Antib Ther, 2020 May 19; 3(2). PMID: 32421049    Free PMC article.
Inducers, Attractors and Modulators of CD4+ Treg Cells in Non-Small-Cell Lung Cancer.
Mengxiao Xie, Jia Wei, Jian Xu.
Front Immunol, 2020 May 20; 11. PMID: 32425930    Free PMC article.
Antinuclear Antibodies With a Homogeneous and Speckled Immunofluorescence Pattern Are Associated With Lack of Cancer While Those With a Nucleolar Pattern With the Presence of Cancer.
Amandine Gauderon, Pascale Roux-Lombard, David Spoerl.
Front Med (Lausanne), 2020 May 20; 7. PMID: 32426359    Free PMC article.
A guide to cancer immunotherapy: from T cell basic science to clinical practice.
Alex D Waldman, Jill M Fritz, Michael J Lenardo.
Nat Rev Immunol, 2020 May 21; 20(11). PMID: 32433532    Free PMC article.
Targeting pulmonary tumor microenvironment with CXCR4-inhibiting nanocomplex to enhance anti-PD-L1 immunotherapy.
Zhaoting Li, Yixin Wang, +3 authors, Minjie Sun.
Sci Adv, 2020 May 23; 6(20). PMID: 32440550    Free PMC article.
Tumor suppression of novel anti-PD-1 antibodies mediated through CD28 costimulatory pathway.
Craig Fenwick, Juan-Luis Loredo-Varela, +11 authors, Giuseppe Pantaleo.
J Exp Med, 2019 May 28; 216(7). PMID: 31123083    Free PMC article.
Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.
Hanjie Li, Anne M van der Leun, +15 authors, Ido Amit.
Cell, 2019 Jan 01; 176(4). PMID: 30595452    Free PMC article.
Highly Cited.
Engineering nanoparticles to reprogram radiotherapy and immunotherapy: recent advances and future challenges.
Jing Jin, Qijie Zhao.
J Nanobiotechnology, 2020 May 16; 18(1). PMID: 32408880    Free PMC article.
The Tumor Microenvironment in the Response to Immune Checkpoint Blockade Therapies.
Florent Petitprez, Maxime Meylan, +2 authors, Wolf H Fridman.
Front Immunol, 2020 May 28; 11. PMID: 32457745    Free PMC article.
Engineered IL-21 Cytokine Muteins Fused to Anti-PD-1 Antibodies Can Improve CD8+ T Cell Function and Anti-tumor Immunity.
Shanling Shen, Gail Sckisel, +13 authors, Khaled Ali.
Front Immunol, 2020 May 28; 11. PMID: 32457754    Free PMC article.
Relevance of immune cell and tumor microenvironment imaging in the new era of immunotherapy.
Filippo Galli, Jesus Vera Aguilera, +3 authors, Alberto Signore.
J Exp Clin Cancer Res, 2020 May 20; 39(1). PMID: 32423420    Free PMC article.
Association of Germline Variants in Natural Killer Cells With Tumor Immune Microenvironment Subtypes, Tumor-Infiltrating Lymphocytes, Immunotherapy Response, Clinical Outcomes, and Cancer Risk.
Xue Xu, Jianqiang Li, +7 authors, Edwin Wang.
JAMA Netw Open, 2019 Sep 05; 2(9). PMID: 31483464    Free PMC article.
Minimal PD-1 expression in mouse and human NK cells under diverse conditions.
Sean J Judge, Cordelia Dunai, +13 authors, William J Murphy.
J Clin Invest, 2020 Mar 07; 130(6). PMID: 32134744    Free PMC article.
Sindbis Virus with Anti-OX40 Overcomes the Immunosuppressive Tumor Microenvironment of Low-Immunogenic Tumors.
Iris Scherwitzl, Silvana Opp, +5 authors, Daniel Meruelo.
Mol Ther Oncolytics, 2020 Jun 02; 17. PMID: 32478167    Free PMC article.
Scientific Rationale for Combination Immunotherapy of Hepatocellular Carcinoma with Anti-PD-1/PD-L1 and Anti-CTLA-4 Antibodies.
Masatoshi Kudo.
Liver Cancer, 2020 Jun 02; 8(6). PMID: 32479569    Free PMC article.
The efficacy and safety of immune checkpoint inhibitors in non-small cell lung cancer patients of different age groups: a meta-analysis.
S-Y Zheng, H-J Cui, +8 authors, X Jiang.
Clin Transl Oncol, 2019 Nov 22; 22(7). PMID: 31748961    Free PMC article.
CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer.
Hua Zhang, Camilla L Christensen, +46 authors, Kwok-Kin Wong.
Cancer Cell, 2019 Dec 31; 37(1). PMID: 31883968    Free PMC article.
Vaccine efficacy against primary and metastatic cancer with in vitro-generated CD103+ conventional dendritic cells.
Yifan Zhou, Natalie Slone, +6 authors, Stephanie S Watowich.
J Immunother Cancer, 2020 Apr 11; 8(1). PMID: 32273347    Free PMC article.
PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2.
Xiaozheng Xu, Bowen Hou, +10 authors, Enfu Hui.
J Cell Biol, 2020 May 22; 219(6). PMID: 32437509    Free PMC article.
Immunotherapy in colorectal cancer: rationale, challenges and potential.
Karuna Ganesh, Zsofia K Stadler, +4 authors, Luis A Diaz.
Nat Rev Gastroenterol Hepatol, 2019 Mar 20; 16(6). PMID: 30886395    Free PMC article.
Highly Cited. Review.
Immune-checkpoint molecules on regulatory T-cells as a potential therapeutic target in head and neck squamous cell cancers.
Susumu Suzuki, Tetsuya Ogawa, +7 authors, Toyonori Tsuzuki.
Cancer Sci, 2020 Apr 19; 111(6). PMID: 32304268    Free PMC article.
miR-128 Regulates Tumor Cell CD47 Expression and Promotes Anti-tumor Immunity in Pancreatic Cancer.
Qing Xi, Ying Chen, +7 authors, Rongxin Zhang.
Front Immunol, 2020 Jun 17; 11. PMID: 32536914    Free PMC article.
Microbiota in cancer development and treatment.
Muhammad Hassan Raza, Kamni Gul, +8 authors, Muhammad Arshad.
J Cancer Res Clin Oncol, 2018 Dec 14; 145(1). PMID: 30542789
Novel Immunotherapy Combinations.
Babar Bashir, Melissa A Wilson.
Curr Oncol Rep, 2019 Nov 07; 21(11). PMID: 31696332
PET Radiopharmaceuticals for Imaging Chemotherapy-Induced Cardiotoxicity.
Jothilingam Sivapackiam, Monica Sharma, Thomas H Schindler, Vijay Sharma.
Curr Cardiol Rep, 2020 Jun 21; 22(8). PMID: 32562004    Free PMC article.
From Molecular Mechanisms to Clinical Management of Antineoplastic Drug-Induced Cardiovascular Toxicity: A Translational Overview.
Carlo Gabriele Tocchetti, Christian Cadeddu, +12 authors, Giuseppe Mercuro.
Antioxid Redox Signal, 2017 Apr 12; 30(18). PMID: 28398124    Free PMC article.
Immune Checkpoints Contribute Corneal Immune Privilege: Implications for Dry Eye Associated with Checkpoint Inhibitors.
Junko Hori, Tomoyuki Kunishige, Yuji Nakano.
Int J Mol Sci, 2020 Jun 04; 21(11). PMID: 32486493    Free PMC article.
T Cells and Regulated Cell Death: Kill or Be Killed.
Johan Spetz, Adam G Presser, Kristopher A Sarosiek.
Int Rev Cell Mol Biol, 2019 Jan 13; 342. PMID: 30635093    Free PMC article.
New emerging targets in cancer immunotherapy: the role of neoantigens.
Leticia De Mattos-Arruda, Juan Blanco-Heredia, +2 authors, Julià Blanco.
ESMO Open, 2020 Apr 10; 4(Suppl 3). PMID: 32269031    Free PMC article.
A Cu9S5 nanoparticle-based CpG delivery system for synergistic photothermal-, photodynamic- and immunotherapy.
Lulu Zhou, Lv Chen, +6 authors, Shuo Shi.
Commun Biol, 2020 Jul 06; 3(1). PMID: 32620811    Free PMC article.
A phase I study of multi-HLA-binding peptides derived from heat shock protein 70/glypican-3 and a novel combination adjuvant of hLAG-3Ig and Poly-ICLC for patients with metastatic gastrointestinal cancers: YNP01 trial.
Masao Nakajima, Shoichi Hazama, +21 authors, Hiroaki Nagano.
Cancer Immunol Immunother, 2020 Mar 29; 69(8). PMID: 32219501    Free PMC article.
Making Checkpoint Inhibitors Part of Treatment of Patients With Locally Advanced Lung Cancers: The Time Is Now.
Mark G Kris, Corinne Faivre-Finn, +4 authors, Stephen Swisher.
Am Soc Clin Oncol Educ Book, 2020 Apr 17; 40. PMID: 32298162    Free PMC article.
Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer.
Shuo Wang, Yuan Qu, +7 authors, Zusen Fan.
Cell Res, 2020 May 06; 30(7). PMID: 32367039    Free PMC article.
Glycogen Synthase Kinase 3β in Cancer Biology and Treatment.
Takahiro Domoto, Masahiro Uehara, Dilireba Bolidong, Toshinari Minamoto.
Cells, 2020 Jun 07; 9(6). PMID: 32503133    Free PMC article.
Surface-Enhanced Raman Spectroscopy for Cancer Immunotherapy Applications: Opportunities, Challenges, and Current Progress in Nanomaterial Strategies.
Shuvashis Dey, Matt Trau, Kevin M Koo.
Nanomaterials (Basel), 2020 Jun 18; 10(6). PMID: 32545182    Free PMC article.
Uncovering the Tumor Antigen Landscape: What to Know about the Discovery Process.
Sara Feola, Jacopo Chiaro, Beatriz Martins, Vincenzo Cerullo.
Cancers (Basel), 2020 Jun 27; 12(6). PMID: 32585818    Free PMC article.
Cancer systems immunology.
Nathan E Reticker-Flynn, Edgar G Engleman.
Elife, 2020 Jul 14; 9. PMID: 32657757    Free PMC article.
Current challenges for assessing the long-term clinical benefit of cancer immunotherapy: a multi-stakeholder perspective.
Casey Quinn, Louis P Garrison, +8 authors, Elise Wu.
J Immunother Cancer, 2020 Jul 15; 8(2). PMID: 32661115    Free PMC article.
A Review of MicroRNA in Uveal Melanoma.
Yi Fan Li, Li Dong, Yang Li, Wen Bin Wei.
Onco Targets Ther, 2020 Jul 17; 13. PMID: 32669855    Free PMC article.
Heme Oxygenase 1-Targeted Hybrid Nanoparticle for Chemo- and Immuno-Combination Therapy in Acute Myelogenous Leukemia.
Seok-Beom Yong, Jaehyun Kim, +3 authors, Yong-Hee Kim.
Adv Sci (Weinh), 2020 Jul 17; 7(13). PMID: 32670766    Free PMC article.
Prognostic value of immune checkpoint molecules in breast cancer.
Jun Fang, Feng Chen, +3 authors, Yuezhen Wang.
Biosci Rep, 2020 Jul 01; 40(7). PMID: 32602545    Free PMC article.
Nanotechnology Strategies To Advance Outcomes in Clinical Cancer Care.
Christopher M Hartshorn, Michelle S Bradbury, +6 authors, Piotr Grodzinski.
ACS Nano, 2017 Dec 20; 12(1). PMID: 29257865    Free PMC article.
Overcoming Tumor Resistance to Oncolyticvaccinia Virus with Anti-PD-1-Based Combination Therapy by Inducing Antitumor Immunity in the Tumor Microenvironment.
So Young Yoo, Narayanasamy Badrinath, +2 authors, Jeong Heo.
Vaccines (Basel), 2020 Jun 25; 8(2). PMID: 32575351    Free PMC article.
Local injection of CCL19-expressing mesenchymal stem cells augments the therapeutic efficacy of anti-PD-L1 antibody by promoting infiltration of immune cells.
Yuichi Iida, Rintaro Yoshikawa, +5 authors, Mamoru Harada.
J Immunother Cancer, 2020 Jul 18; 8(2). PMID: 32675195    Free PMC article.
Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus.
Marco Mineo, Shawn M Lyons, +20 authors, E Antonio Chiocca.
Mol Cell, 2020 Jun 07; 78(6). PMID: 32504554    Free PMC article.
Studying the biology of cytotoxic T lymphocytes in vivo with a fluorescent granzyme B-mTFP knock-in mouse.
Praneeth Chitirala, Hsin-Fang Chang, +10 authors, Jens Rettig.
Elife, 2020 Jul 23; 9. PMID: 32696761    Free PMC article.
Cancer Inflammation and Cytokines.
Maria Rosaria Galdiero, Gianni Marone, Alberto Mantovani.
Cold Spring Harb Perspect Biol, 2017 Aug 06; 10(8). PMID: 28778871    Free PMC article.
The promise of combining cancer vaccine and checkpoint blockade for treating HPV-related cancer.
Takeo Shibata, Benjamin J Lieblong, Toshiyuki Sasagawa, Mayumi Nakagawa.
Cancer Treat Rev, 2019 Jul 16; 78. PMID: 31302573    Free PMC article.
Obesity and CD8 T cell metabolism: Implications for anti-tumor immunity and cancer immunotherapy outcomes.
William J Turbitt, Claire Buchta Rosean, K Scott Weber, Lyse A Norian.
Immunol Rev, 2020 Mar 12; 295(1). PMID: 32157710    Free PMC article.
Tumor-Associated CD163+ M2 Macrophage Infiltration is Highly Associated with PD-L1 Expression in Cervical Cancer.
Fan Guo, Yang-Chun Feng, +7 authors, Xiu-Min Ma.
Cancer Manag Res, 2020 Aug 09; 12. PMID: 32765086    Free PMC article.
Immune checkpoint targeting TIGIT in hepatocellular carcinoma.
Qiuxian Zheng, Jia Xu, +6 authors, Zhi Chen.
Am J Transl Res, 2020 Aug 11; 12(7). PMID: 32774695    Free PMC article.
Nanomedicine and Onco-Immunotherapy: From the Bench to Bedside to Biomarkers.
Vanessa Acebes-Fernández, Alicia Landeria-Viñuela, +5 authors, Manuel Fuentes.
Nanomaterials (Basel), 2020 Jul 03; 10(7). PMID: 32610601    Free PMC article.
RORα Regulates Cholesterol Metabolism of CD8+ T Cells for Anticancer Immunity.
In Kyu Lee, Hyerin Song, +5 authors, Ji Min Lee.
Cancers (Basel), 2020 Jul 03; 12(7). PMID: 32610705    Free PMC article.
Necroptotic-susceptible dendritic cells exhibit enhanced antitumor activities in mice.
Zhanran Zhao, Guangzhi Zhang, Yuefang Sun, Astar Winoto.
Immun Inflamm Dis, 2020 Jul 15; 8(3). PMID: 32663380    Free PMC article.
Epigenetic Mechanisms of Resistance to Immune Checkpoint Inhibitors.
Alexandre Perrier, Audrey Didelot, +2 authors, Simon Garinet.
Biomolecules, 2020 Jul 28; 10(7). PMID: 32708698    Free PMC article.
Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types.
Jasneet Kaur Khalsa, Nina Cheng, +5 authors, Khalid Shah.
Nat Commun, 2020 Aug 09; 11(1). PMID: 32764562    Free PMC article.
Immune-related genes play an important role in the prognosis of patients with testicular germ cell tumor.
Chengjian Ji, Yichun Wang, +4 authors, Ninghong Song.
Ann Transl Med, 2020 Aug 15; 8(14). PMID: 32793710    Free PMC article.
The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications.
Yuanyuan Zhang, Zemin Zhang.
Cell Mol Immunol, 2020 Jul 03; 17(8). PMID: 32612154    Free PMC article.
Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer.
Aitziber Buqué, Norma Bloy, +27 authors, Lorenzo Galluzzi.
Nat Commun, 2020 Aug 01; 11(1). PMID: 32732875    Free PMC article.
A nanoscale metal organic frameworks-based vaccine synergises with PD-1 blockade to potentiate anti-tumour immunity.
Xia Li, Xiupeng Wang, Atsuo Ito, Noriko M Tsuji.
Nat Commun, 2020 Aug 02; 11(1). PMID: 32737343    Free PMC article.
Modulation of SRSF2 expression reverses the exhaustion of TILs via the epigenetic regulation of immune checkpoint molecules.
Ziqiang Wang, Kun Li, +6 authors, Weiren Huang.
Cell Mol Life Sci, 2019 Dec 16; 77(17). PMID: 31838573    Free PMC article.
B-cell epitope peptide cancer vaccines: a new paradigm for combination immunotherapies with novel checkpoint peptide vaccine.
Pravin Tp Kaumaya.
Future Oncol, 2020 Jun 23; 16(23). PMID: 32564612    Free PMC article.
Melanoma brain metastases: review of histopathological features and immune-molecular aspects.
Lorenzo Salvati, Mario Mandalà, Daniela Massi.
Melanoma Manag, 2020 Aug 22; 7(2). PMID: 32821376    Free PMC article.
Administration of low-dose combination anti-CTLA4, anti-CD137, and anti-OX40 into murine tumor or proximal to the tumor draining lymph node induces systemic tumor regression.
Jonathan P O Hebb, Adriane R Mosley, +4 authors, Dean W Felsher.
Cancer Immunol Immunother, 2017 Sep 15; 67(1). PMID: 28905118    Free PMC article.
Tumor Cell-Intrinsic Immunometabolism and Precision Nutrition in Cancer Immunotherapy.
Elisabet Cuyàs, Sara Verdura, +4 authors, Javier A Menendez.
Cancers (Basel), 2020 Jul 08; 12(7). PMID: 32630618    Free PMC article.
Recent Advances and Challenges in the Treatment of Rhabdomyosarcoma.
Shinji Miwa, Norio Yamamoto, +3 authors, Hiroyuki Tsuchiya.
Cancers (Basel), 2020 Jul 08; 12(7). PMID: 32630642    Free PMC article.
Role of Telomeres and Telomeric Proteins in Human Malignancies and Their Therapeutic Potential.
Stina George Fernandes, Rebecca Dsouza, +5 authors, Ekta Khattar.
Cancers (Basel), 2020 Jul 18; 12(7). PMID: 32674474    Free PMC article.
Harnessing the Complete Repertoire of Conventional Dendritic Cell Functions for Cancer Immunotherapy.
Lukas Amon, Lukas Hatscher, +2 authors, Christian H K Lehmann.
Pharmaceutics, 2020 Jul 18; 12(7). PMID: 32674488    Free PMC article.
Therapeutic Strategies for Overcoming Immunotherapy Resistance Mediated by Immunosuppressive Factors of the Glioblastoma Microenvironment.
Tsubasa Miyazaki, Eiichi Ishikawa, Narushi Sugii, Masahide Matsuda.
Cancers (Basel), 2020 Jul 28; 12(7). PMID: 32707672    Free PMC article.
Immune Checkpoint Inhibitors in Oral Cavity Squamous Cell Carcinoma and Oral Potentially Malignant Disorders: A Systematic Review.
Omar Kujan, Bede van Schaijik, Camile S Farah.
Cancers (Basel), 2020 Jul 28; 12(7). PMID: 32708945    Free PMC article.
Deubiquitinating Enzyme: A Potential Secondary Checkpoint of Cancer Immunity.
Xing Huang, Xiaozhen Zhang, +6 authors, Xueli Bai.
Front Oncol, 2020 Aug 28; 10. PMID: 32850399    Free PMC article.
Progress in Neoantigen Targeted Cancer Immunotherapies.
Xue-Jiao Han, Xue-Lei Ma, +3 authors, Xia-Wei Wei.
Front Cell Dev Biol, 2020 Aug 28; 8. PMID: 32850843    Free PMC article.
Tumor Microenvironment in Ovarian Cancer: Function and Therapeutic Strategy.
Yanfei Yang, Yang Yang, +2 authors, Xiawei Wei.
Front Cell Dev Biol, 2020 Aug 28; 8. PMID: 32850861    Free PMC article.
Early Onset Immune-Related Adverse Event to Identify Pseudo-Progression in a Patient With Ovarian Cancer Treated With Nivolumab: A Case Report and Review of the Literature.
Hui Li, Xin Zhou, +6 authors, Jun Chen.
Front Med (Lausanne), 2020 Aug 28; 7. PMID: 32850889    Free PMC article.
Overcoming resistance to STING agonist therapy to incite durable protective antitumor immunity.
Henrique Lemos, Rong Ou, +6 authors, Andrew L Mellor.
J Immunother Cancer, 2020 Aug 28; 8(2). PMID: 32847988    Free PMC article.
[Development of programmed death receptor-1 and programmed death receptor-1 ligand in oral squamous cell carcinoma].
Zhi-Hong Chen, Ya-Dong Wu.
Hua Xi Kou Qiang Yi Xue Za Zhi, 2020 Sep 01; 38(4). PMID: 32865367    Free PMC article.
Distinct tumor immune microenvironments in primary and metastatic lesions in gastric cancer patients.
Seung-Myoung Son, Chang Gok Woo, +12 authors, Hye Sook Han.
Sci Rep, 2020 Sep 02; 10(1). PMID: 32868848    Free PMC article.
Efficacy and predictive factors of immune checkpoint inhibitors in metastatic breast cancer: a systematic review and meta-analysis.
Yutian Zou, Xuxiazi Zou, +4 authors, Xiaoming Xie.
Ther Adv Med Oncol, 2020 Sep 03; 12. PMID: 32874208    Free PMC article.
CMTM6 significantly relates to PD-L1 and predicts the prognosis of gastric cancer patients.
Xin Li, Ling Chen, +2 authors, Jia Li.
PeerJ, 2020 Sep 03; 8. PMID: 32874775    Free PMC article.
Comprehensive profiling of immune-related genes in soft tissue sarcoma patients.
Chuan Hu, Bo Chen, +6 authors, Chengliang Zhao.
J Transl Med, 2020 Sep 03; 18(1). PMID: 32873319    Free PMC article.
Controlling TIME: How MNK Kinases Function to Shape Tumor Immunity.
Thao N D Pham, Christina Spaulding, Hidayatullah G Munshi.
Cancers (Basel), 2020 Aug 01; 12(8). PMID: 32731503    Free PMC article.
Necroptosis in Immuno-Oncology and Cancer Immunotherapy.
Jenny Sprooten, Pieter De Wijngaert, +8 authors, Abhishek D Garg.
Cells, 2020 Aug 06; 9(8). PMID: 32752206    Free PMC article.
Can Exercise-Induced Modulation of the Tumor Physiologic Microenvironment Improve Antitumor Immunity?
Xiaojie Zhang, Kathleen A Ashcraft, +2 authors, Mark W Dewhirst.
Cancer Res, 2019 May 10; 79(10). PMID: 31068341    Free PMC article.
Carcinogenesis: Failure of resolution of inflammation?
Anna Fishbein, Bruce D Hammock, Charles N Serhan, Dipak Panigrahy.
Pharmacol Ther, 2020 Sep 07; 218. PMID: 32891711    Free PMC article.
Combinatorial approach to cancer immunotherapy: strength in numbers.
Anna E Vilgelm, Douglas B Johnson, Ann Richmond.
J Leukoc Biol, 2016 Jun 04; 100(2). PMID: 27256570    Free PMC article.
TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy.
Martina Molgora, Ekaterina Esaulova, +18 authors, Marco Colonna.
Cell, 2020 Aug 14; 182(4). PMID: 32783918    Free PMC article.
PDIA3 correlates with clinical malignant features and immune signature in human gliomas.
Hao Zhang, Yulai Zhou, +6 authors, Hui Cao.
Aging (Albany NY), 2020 Jul 21; 12(15). PMID: 32687065    Free PMC article.
Current status of treatment with immune checkpoint inhibitors for gastrointestinal, hepatobiliary, and pancreatic cancers.
Yuji Eso, Hiroshi Seno.
Therap Adv Gastroenterol, 2020 Sep 12; 13. PMID: 32913444    Free PMC article.
IFNγ and TNFα synergistically promote galectin 9 secretion by human osteosarcoma cells MG-63 to prevent T cell killing.
Yuchang Liu, Junzhong Luo, +2 authors, Xuan Wang.
Int J Clin Exp Pathol, 2020 Sep 15; 13(8). PMID: 32922595    Free PMC article.
Cancer immunotherapy using a polysaccharide from Codium fragile in a murine model.
Hae-Bin Park, Seong-Min Lim, +3 authors, Jun-O Jin.
Oncoimmunology, 2020 Sep 15; 9(1). PMID: 32923129    Free PMC article.
Trial Watch: experimental TLR7/TLR8 agonists for oncological indications.
Giorgio Frega, Qi Wu, +4 authors, Oliver Kepp.
Oncoimmunology, 2020 Sep 17; 9(1). PMID: 32934889    Free PMC article.
Mechanisms and microbial influences on CTLA-4 and PD-1-based immunotherapy in the treatment of cancer: a narrative review.
Peter L Miller, Tiffany L Carson.
Gut Pathog, 2020 Sep 19; 12. PMID: 32944086    Free PMC article.
Digital quantitative assessment of PD-L1 using digital spatial profiling.
Swati Gupta, Jon Zugazagoitia, +2 authors, David L Rimm.
Lab Invest, 2020 Apr 07; 100(10). PMID: 32249818    Free PMC article.
PRMT5 control of cGAS/STING and NLRC5 pathways defines melanoma response to antitumor immunity.
Hyungsoo Kim, Heejung Kim, +4 authors, Ze'ev A Ronai.
Sci Transl Med, 2020 Jul 10; 12(551). PMID: 32641491    Free PMC article.
Progress of immune checkpoint LAG-3 in immunotherapy.
Chanchan Shan, Xing Li, Jian Zhang.
Oncol Lett, 2020 Sep 24; 20(5). PMID: 32963613    Free PMC article.
Classification of Muscle-Invasive Bladder Cancer Based on Immunogenomic Profiling.
Xianghong Zhou, Shi Qiu, +5 authors, Qiang Wei.
Front Oncol, 2020 Sep 26; 10. PMID: 32974156    Free PMC article.
Immunotherapy, Radiotherapy, and Hyperthermia: A Combined Therapeutic Approach in Pancreatic Cancer Treatment.
Javed Mahmood, Hem D Shukla, +6 authors, Zeljko Vujaskovic.
Cancers (Basel), 2018 Nov 30; 10(12). PMID: 30486519    Free PMC article.
The promising immune checkpoint LAG-3: from tumor microenvironment to cancer immunotherapy.
Long Long, Xue Zhang, +4 authors, Honglei Chen.
Genes Cancer, 2019 Jan 04; 9(5-6). PMID: 30603054    Free PMC article.
Highly Cited. Review.
Immune checkpoint therapy and type 1 diabetes.
Hiroshi Ikegami, Yumiko Kawabata, Shinsuke Noso.
Diabetol Int, 2016 Jul 05; 7(3). PMID: 30603267    Free PMC article.
Principles of Immunotherapy: Implications for Treatment Strategies in Cancer and Infectious Diseases.
Krupa Naran, Trishana Nundalall, Shivan Chetty, Stefan Barth.
Front Microbiol, 2019 Jan 10; 9. PMID: 30622524    Free PMC article.
Engineering Precision Medicine.
Wujin Sun, Junmin Lee, +3 authors, Ali Khademhosseini.
Adv Sci (Weinh), 2019 Jan 16; 6(1). PMID: 30643715    Free PMC article.
Combination of photodynamic therapy (PDT) and anti-tumor immunity in cancer therapy.
Hee Sook Hwang, Heejun Shin, Jieun Han, Kun Na.
J Pharm Investig, 2019 Jan 27; 48(2). PMID: 30680248    Free PMC article.
New insights into the pathogenesis and treatment of non-viral hepatocellular carcinoma: a balancing act between immunosuppression and immunosurveillance.
Michael Karin.
Precis Clin Med, 2019 Jan 29; 1(1). PMID: 30687560    Free PMC article.
Multiscale Agent-Based and Hybrid Modeling of the Tumor Immune Microenvironment.
Kerri-Ann Norton, Chang Gong, Samira Jamalian, Aleksander S Popel.
Processes (Basel), 2019 Feb 01; 7(1). PMID: 30701168    Free PMC article.
Highly Cited.
Highlight report: Activating tumor-specific T-cells for breast cancer therapy.
Mikheil Gogiashvili.
EXCLI J, 2019 Feb 05; 17. PMID: 30713484    Free PMC article.
Batf3+ DCs and type I IFN are critical for the efficacy of neoadjuvant cancer immunotherapy.
Jing Liu, Elisa A Rozeman, +5 authors, Michele W L Teng.
Oncoimmunology, 2019 Feb 05; 8(2). PMID: 30713806    Free PMC article.
Releasing the Immune System Brakes Using siRNAs Enhances Cancer Immunotherapy.
Mouldy Sioud.
Cancers (Basel), 2019 Feb 06; 11(2). PMID: 30717461    Free PMC article.
Alteration of Adaptive Immunity in a Colorectal Peritoneal Carcinomatosis Model.
Rongchen Shi, Wei Xiang, +4 authors, Fengtian He.
J Cancer, 2019 Feb 06; 10(2). PMID: 30719130    Free PMC article.
Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg et al. (2017).
Lijie Zhai, Erik Ladomersky, +9 authors, Derek A Wainwright.
Oncoimmunology, 2019 Feb 07; 8(3). PMID: 30723577    Free PMC article.
CIITA-related block of HLA class II expression, upregulation of HLA class I, and heterogeneous expression of immune checkpoints in hepatocarcinomas: implications for new therapeutic approaches.
Elise Ramia, Anna Maria Chiaravalli, +4 authors, Greta Forlani.
Oncoimmunology, 2019 Feb 07; 8(3). PMID: 30723578    Free PMC article.
Pembrolizumab-related renal toxicities: diagnosis first, treatment later.
Ben Sprangers.
Clin Kidney J, 2019 Feb 13; 12(1). PMID: 30746131    Free PMC article.
Turning the corner on therapeutic cancer vaccines.
Robert E Hollingsworth, Kathrin Jansen.
NPJ Vaccines, 2019 Feb 19; 4. PMID: 30774998    Free PMC article.
Highly Cited. Review.
Mouse-Derived Isograft (MDI) In Vivo Tumor Models I. Spontaneous sMDI Models: Characterization and Cancer Therapeutic Approaches.
Peter Jantscheff, Janette Beshay, +3 authors, Holger Weber.
Cancers (Basel), 2019 Feb 23; 11(2). PMID: 30791466    Free PMC article.
Characteristics and clinical course of type 1 diabetes mellitus related to anti-programmed cell death-1 therapy.
Megu Yamaguchi Baden, Akihisa Imagawa, +20 authors, consultation of the Japan Diabetes Society Committee on Type 1 Diabetes Mellitus Research.
Diabetol Int, 2019 Feb 26; 10(1). PMID: 30800564    Free PMC article.
Exosomes: biogenesis, biologic function and clinical potential.
Yuan Zhang, Yunfeng Liu, Haiying Liu, Wai Ho Tang.
Cell Biosci, 2019 Mar 01; 9. PMID: 30815248    Free PMC article.
Highly Cited. Review.
Combination Cancer Immunotherapy with Molecular Targeted Agents/Anti-CTLA-4 Antibody for Hepatocellular Carcinoma.
Masatoshi Kudo.
Liver Cancer, 2019 Mar 01; 8(1). PMID: 30815391    Free PMC article.
Nuclear Theranostics in Asia: In vivo Companion Diagnostics.
Dong Soo Lee, Gi Jeong Cheon.
Nucl Med Mol Imaging, 2019 Mar 05; 53(1). PMID: 30828392    Free PMC article.
Correlation between patients' age and cancer immunotherapy efficacy.
Qiong Wu, Qiuhong Wang, +10 authors, You Lang Zhou.
Oncoimmunology, 2019 Mar 25; 8(4). PMID: 30906662    Free PMC article.
Emerging Nano-/Microapproaches for Cancer Immunotherapy.
Yu Mi, C Tilden Hagan, Benjamin G Vincent, Andrew Z Wang.
Adv Sci (Weinh), 2019 Apr 03; 6(6). PMID: 30937265    Free PMC article.
Extracellular Vesicle-Based Therapeutic Targeting of β-Catenin to Modulate Anticancer Immune Responses in Hepatocellular Cancer.
Akiko Matsuda, Kaori Ishiguro, Irene K Yan, Tushar Patel.
Hepatol Commun, 2019 Apr 13; 3(4). PMID: 30976743    Free PMC article.
Carrier-free nano-integrated strategy for synergetic cancer anti-angiogenic therapy and phototherapy.
Zheng Wei, Pingping Liang, +7 authors, Xiaochen Dong.
Chem Sci, 2019 Apr 19; 10(9). PMID: 30996997    Free PMC article.
Irradiation to Improve the Response to Immunotherapeutic Agents in Glioblastomas.
Jean Philippe Nesseler, Dorthe Schaue, +4 authors, Philippe Nickers.
Adv Radiat Oncol, 2019 Apr 24; 4(2). PMID: 31011672    Free PMC article.
Immunogenic Cell Death and Immunotherapy of Multiple Myeloma.
Alfonso Serrano-Del Valle, Alberto Anel, Javier Naval, Isabel Marzo.
Front Cell Dev Biol, 2019 May 02; 7. PMID: 31041312    Free PMC article.
Highly Cited. Review.
Single-cell technologies for profiling T cells to enable monitoring of immunotherapies.
Xingyue An, Navin Varadarajan.
Curr Opin Chem Eng, 2018 Mar 01; 19. PMID: 31131208    Free PMC article.
Elevated PD-L1 expression predicts poor survival outcomes in patients with cervical cancer.
Xiaobin Gu, Meilian Dong, +8 authors, Yonggang Shi.
Cancer Cell Int, 2019 May 31; 19. PMID: 31143091    Free PMC article.
Liquid biopsy for lung cancer immunotherapy.
Liang-Liang Cai, Jie Wang.
Oncol Lett, 2019 Jun 13; 17(6). PMID: 31186680    Free PMC article.
MicroRNAs aid the assessment of programmed death ligand 1 expression in patients with non-small cell lung cancer.
Anna Grenda, Marcin Nicoś, +8 authors, Janusz Milanowski.
Oncol Lett, 2019 Jun 13; 17(6). PMID: 31186735    Free PMC article.
Evaluating a Single Domain Antibody Targeting Human PD-L1 as a Nuclear Imaging and Therapeutic Agent.
Katrijn Broos, Quentin Lecocq, +9 authors, Karine Breckpot.
Cancers (Basel), 2019 Jun 27; 11(6). PMID: 31234464    Free PMC article.
Hypophysitis induced by immune checkpoint inhibitors in a Scottish melanoma population.
Khor Zhong Wei, Mark Baxter, Richard Casasola.