. 2015 Apr; 348(6230):69-74.
doi: 10.1126/science.aaa4971.

Neoantigens in cancer immunotherapy

Ton N Schumacher 1 Robert D Schreiber 2 
  • PMID: 25838375
  •     1737 citations


The clinical relevance of T cells in the control of a diverse set of human cancers is now beyond doubt. However, the nature of the antigens that allow the immune system to distinguish cancer cells from noncancer cells has long remained obscure. Recent technological innovations have made it possible to dissect the immune response to patient-specific neoantigens that arise as a consequence of tumor-specific mutations, and emerging data suggest that recognition of such neoantigens is a major factor in the activity of clinical immunotherapies. These observations indicate that neoantigen load may form a biomarker in cancer immunotherapy and provide an incentive for the development of novel therapeutic approaches that selectively enhance T cell reactivity against this class of antigens.

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Highly Cited.
New Strategies for the Treatment of Solid Tumors with CAR-T Cells.
Hao Zhang, Zhen-Long Ye, +3 authors, Qi-Jun Qian.
Int J Biol Sci, 2016 May 20; 12(6). PMID: 27194949    Free PMC article.
Effects of microsatellite instability on recurrence patterns and outcomes in colorectal cancers.
Chang Gon Kim, Joong Bae Ahn, +11 authors, Sang Joon Shin.
Br J Cancer, 2016 May 27; 115(1). PMID: 27228287    Free PMC article.
Current status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapy.
Weijie Ma, Barbara M Gilligan, Jianda Yuan, Tianhong Li.
J Hematol Oncol, 2016 May 29; 9(1). PMID: 27234522    Free PMC article.
Highly Cited. Review.
Checkpoint Inhibitors and Their Application in Breast Cancer.
Davide Bedognetti, Cristina Maccalli, +2 authors, Barbara Seliger.
Breast Care (Basel), 2016 May 31; 11(2). PMID: 27239172    Free PMC article.
Monitoring immune responses in the tumor microenvironment.
Jennifer A Wargo, Sangeetha M Reddy, Alexandre Reuben, Padmanee Sharma.
Curr Opin Immunol, 2016 May 31; 41. PMID: 27240055    Free PMC article.
Increased incidence of FBXW7 and POLE proofreading domain mutations in young adult colorectal cancers.
Nishi Kothari, Jamie K Teer, +7 authors, David Shibata.
Cancer, 2016 Jun 01; 122(18). PMID: 27244218    Free PMC article.
A second chance for telomerase reverse transcriptase in anticancer immunotherapy.
Maurizio Zanetti.
Nat Rev Clin Oncol, 2016 Nov 03; 14(2). PMID: 27245281
Genetically Engineered Mouse Models of Pancreatic Cancer: The KPC Model (LSL-Kras(G12D/+) ;LSL-Trp53(R172H/+) ;Pdx-1-Cre), Its Variants, and Their Application in Immuno-oncology Drug Discovery.
Jae W Lee, Chad A Komar, +2 authors, Gregory L Beatty.
Curr Protoc Pharmacol, 2016 Jun 02; 73. PMID: 27248578    Free PMC article.
When Genome Maintenance Goes Badly Awry.
Elizabeth M Kass, Mary Ellen Moynahan, Maria Jasin.
Mol Cell, 2016 Jun 04; 62(5). PMID: 27259208    Free PMC article.
Analysis of PD-L1, T-cell infiltrate and HLA expression in chondrosarcoma indicates potential for response to immunotherapy specifically in the dedifferentiated subtype.
Marie Kostine, Arjen Hg Cleven, +3 authors, Judith V M G Bovée.
Mod Pathol, 2016 Jun 18; 29(9). PMID: 27312065
Dendritic cell vaccination in melanoma patients: From promising results to future perspectives.
Steve Boudewijns, Martine Bloemendal, +2 authors, Gerty Schreibelt.
Hum Vaccin Immunother, 2016 Jun 21; 12(10). PMID: 27322496    Free PMC article.
Molecular characterisation of cutaneous melanoma: creating a framework for targeted and immune therapies.
Shivshankari Rajkumar, Ian R Watson.
Br J Cancer, 2016 Jun 24; 115(2). PMID: 27336610    Free PMC article.
Hypoxic stress: obstacles and opportunities for innovative immunotherapy of cancer.
S Chouaib, M Z Noman, K Kosmatopoulos, M A Curran.
Oncogene, 2016 Jun 28; 36(4). PMID: 27345407    Free PMC article.
Highly Cited. Review.
MonoSeq Variant Caller Reveals Novel Mononucleotide Run Indel Mutations in Tumors with Defective DNA Mismatch Repair.
Christopher J Walker, Mario A Miranda, +10 authors, Paul J Goodfellow.
Hum Mutat, 2016 Jun 28; 37(10). PMID: 27346418    Free PMC article.
Neoantigen landscape dynamics during human melanoma-T cell interactions.
Els M E Verdegaal, Noel F C C de Miranda, +11 authors, Sjoerd H van der Burg.
Nature, 2016 Jun 29; 536(7614). PMID: 27350335
Highly Cited.
Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis-Masters of Survival and Clonality?
Lisa Pleyer, Peter Valent, Richard Greil.
Int J Mol Sci, 2016 Jun 30; 17(7). PMID: 27355944    Free PMC article.
The Immunogenicity of Colorectal Cancer in Relation to Tumor Development and Treatment.
Natasja L de Vries, Marloes Swets, +2 authors, Peter J K Kuppen.
Int J Mol Sci, 2016 Jul 02; 17(7). PMID: 27367680    Free PMC article.
Molecular Profile of Tumor-Specific CD8+ T Cell Hypofunction in a Transplantable Murine Cancer Model.
Katherine A Waugh, Sonia M Leach, +3 authors, Jill E Slansky.
J Immunol, 2016 Jul 03; 197(4). PMID: 27371726    Free PMC article.
Unraveling the molecular details of the innate immune response.
Juan Fernández-Recio.
EBioMedicine, 2016 Jul 05; 9. PMID: 27374315    Free PMC article.
Inhibiting Immune Checkpoints for the Treatment of Bladder Cancer.
S Bidnur, R Savdie, P C Black.
Bladder Cancer, 2016 Jul 05; 2(1). PMID: 27376121    Free PMC article.
Computational genomics tools for dissecting tumour-immune cell interactions.
Hubert Hackl, Pornpimol Charoentong, Francesca Finotello, Zlatko Trajanoski.
Nat Rev Genet, 2016 Jul 05; 17(8). PMID: 27376489
Highly Cited. Review.
Pembrolizumab: first experience with recurrent primary central nervous system (CNS) tumors.
Deborah T Blumenthal, Michal Yalon, +6 authors, Felix Bokstein.
J Neurooncol, 2016 Jul 06; 129(3). PMID: 27377654
Rationale for immune-based therapies in Merkel polyomavirus-positive and -negative Merkel cell carcinomas.
Natalie Vandeven, Paul Nghiem.
Immunotherapy, 2016 Jul 07; 8(8). PMID: 27381685    Free PMC article.
Personalized peptide vaccine-induced immune response associated with long-term survival of a metastatic cholangiocarcinoma patient.
Markus W Löffler, P Anoop Chandran, +28 authors, Hans-Georg Rammensee.
J Hepatol, 2016 Jul 12; 65(4). PMID: 27397612    Free PMC article.
Mutation Drivers of Immunological Responses to Cancer.
Eduard Porta-Pardo, Adam Godzik.
Cancer Immunol Res, 2016 Jul 13; 4(9). PMID: 27401919    Free PMC article.
Harnessing shared antigens and T-cell receptors in cancer: Opportunities and challenges.
Kavita Dhodapkar, Madhav Dhodapkar.
Proc Natl Acad Sci U S A, 2016 Jul 14; 113(29). PMID: 27410048    Free PMC article.
Recent advances and future of immunotherapy for glioblastoma.
Neha Kamran, Alexandra Calinescu, +7 authors, Maria G Castro.
Expert Opin Biol Ther, 2016 Jul 14; 16(10). PMID: 27411023    Free PMC article.
Avidity characterization of genetically engineered T-cells with novel and established approaches.
Victoria Hillerdal, Vanessa F Boura, +2 authors, Magnus Essand.
BMC Immunol, 2016 Jul 15; 17(1). PMID: 27411667    Free PMC article.
Human Leukocyte Antigen (HLA) Peptides Derived from Tumor Antigens Induced by Inhibition of DNA Methylation for Development of Drug-facilitated Immunotherapy.
Bracha Shraibman, Dganit Melamed Kadosh, Eilon Barnea, Arie Admon.
Mol Cell Proteomics, 2016 Jul 15; 15(9). PMID: 27412690    Free PMC article.
Tracking Cancer Genetic Evolution using OncoTrack.
Asoke K Talukder, Mahima Agarwal, Kenneth H Buetow, Patrice P Denèfle.
Sci Rep, 2016 Jul 15; 6. PMID: 27412732    Free PMC article.
Aptamers: A Feasible Technology in Cancer Immunotherapy.
M M Soldevilla, H Villanueva, F Pastor.
J Immunol Res, 2016 Jul 15; 2016. PMID: 27413756    Free PMC article.
The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine.
Andrea Garofalo, Lynette Sholl, +18 authors, Eliezer M Van Allen.
Genome Med, 2016 Jul 28; 8(1). PMID: 27460824    Free PMC article.
Highly Cited.
Leveraging Mechanisms Governing Pancreatic Tumorigenesis To Reduce Pancreatic Cancer Mortality.
Timothy R Donahue, David W Dawson.
Trends Endocrinol Metab, 2016 Oct 23; 27(11). PMID: 27461042    Free PMC article.
A novel dendritic cell targeting HPV16 E7 synthetic vaccine in combination with PD-L1 blockade elicits therapeutic antitumor immunity in mice.
Zhida Liu, Hang Zhou, +2 authors, Mingzhao Zhu.
Oncoimmunology, 2016 Jul 30; 5(6). PMID: 27471615    Free PMC article.
Antitumor vaccination of prostate cancer patients elicits PD-1/PD-L1 regulated antigen-specific immune responses.
Brian T Rekoske, Brian M Olson, Douglas G McNeel.
Oncoimmunology, 2016 Jul 30; 5(6). PMID: 27471641    Free PMC article.
Nivolumab in the treatment of metastatic squamous non-small cell lung cancer: a review of the evidence.
Joline S J Lim, Ross A Soo.
Ther Adv Respir Dis, 2016 Aug 03; 10(5). PMID: 27480166    Free PMC article.
Immunotherapy Expands and Maintains the Function of High-Affinity Tumor-Infiltrating CD8 T Cells In Situ.
Amy E Moran, Fanny Polesso, Andrew D Weinberg.
J Immunol, 2016 Aug 10; 197(6). PMID: 27503208    Free PMC article.
Socializing Individualized T-Cell Cancer Immunotherapy.
Richard G Vile.
Mol Ther, 2016 Aug 11; 24(7). PMID: 27506377    Free PMC article.
Mechanistic insights into the oncolytic activity of vesicular stomatitis virus in cancer immunotherapy.
Boris Simovic, Scott R Walsh, Yonghong Wan.
Oncolytic Virother, 2015 Jan 01; 4. PMID: 27512679    Free PMC article.
HHLA2, a member of the B7 family, is expressed in human osteosarcoma and is associated with metastases and worse survival.
Pratistha Koirala, Michael E Roth, +9 authors, Richard Gorlick.
Sci Rep, 2016 Aug 18; 6. PMID: 27531281    Free PMC article.
Genomic complexity of multiple myeloma and its clinical implications.
Salomon Manier, Karma Z Salem, +3 authors, Irene M Ghobrial.
Nat Rev Clin Oncol, 2016 Nov 03; 14(2). PMID: 27531699
Highly Cited. Review.
Circulating protein and antibody biomarker for personalized cancer immunotherapy.
Jianda Yuan.
J Immunother Cancer, 2016 Aug 18; 4. PMID: 27532021    Free PMC article.
New vaccines: challenges of discovery.
Adel Mahmoud.
Microb Biotechnol, 2016 Aug 19; 9(5). PMID: 27534704    Free PMC article.
New targeted treatments for non-small-cell lung cancer - role of nivolumab.
Giulia Zago, Mirte Muller, Michel van den Heuvel, Paul Baas.
Biologics, 2016 Aug 19; 10. PMID: 27536062    Free PMC article.
sNebula, a network-based algorithm to predict binding between human leukocyte antigens and peptides.
Heng Luo, Hao Ye, +3 authors, Huixiao Hong.
Sci Rep, 2016 Aug 26; 6. PMID: 27558848    Free PMC article.
The CALR exon 9 mutations are shared neoantigens in patients with CALR mutant chronic myeloproliferative neoplasms.
M O Holmström, C H Riley, +2 authors, M H Andersen.
Leukemia, 2016 Aug 26; 30(12). PMID: 27560107
Towards tumor immunodiagnostics.
Helen Kourea, Vassiliki Kotoula.
Ann Transl Med, 2016 Aug 27; 4(14). PMID: 27563650    Free PMC article.
DNA damage, tumor mutational load and their impact on immune responses against cancer.
Michalis Liontos, Ioannis Anastasiou, Aristotelis Bamias, Meletios-Athanasios Dimopoulos.
Ann Transl Med, 2016 Aug 27; 4(14). PMID: 27563651    Free PMC article.
Adaptive immunity programmes in breast cancer.
Frederick S Varn, David W Mullins, +2 authors, Chao Cheng.
Immunology, 2016 Aug 27; 150(1). PMID: 27564847    Free PMC article.
A Pilot Study of Preoperative Single-Dose Ipilimumab and/or Cryoablation in Women with Early-Stage Breast Cancer with Comprehensive Immune Profiling.
Heather L McArthur, Adi Diab, +27 authors, Larry Norton.
Clin Cancer Res, 2016 Nov 05; 22(23). PMID: 27566765    Free PMC article.
Integrative systems medicine approaches to identify molecular targets in lymphoid malignancies.
Raffaele Frazzi, Charles Auffray, +3 authors, Alfredo Cesario.
J Transl Med, 2016 Sep 02; 14. PMID: 27580852    Free PMC article.
Mass spectrometric analysis of the HLA class I peptidome of melanoma cell lines as a promising tool for the identification of putative tumor-associated HLA epitopes.
Andreas Gloger, Danilo Ritz, Tim Fugmann, Dario Neri.
Cancer Immunol Immunother, 2016 Oct 21; 65(11). PMID: 27600516    Free PMC article.
Present Yourself! By MHC Class I and MHC Class II Molecules.
Kenneth L Rock, Eric Reits, Jacques Neefjes.
Trends Immunol, 2016 Sep 12; 37(11). PMID: 27614798    Free PMC article.
Highly Cited. Review.
In Vitro Assessment of the Expression and T Cell Immunogenicity of the Tumor-Associated Antigens BORIS, MUC1, hTERT, MAGE-A3 and Sp17 in Uterine Cancer.
Anke Vanderstraeten, Sandra Tuyaerts, +4 authors, Frederic Amant.
Int J Mol Sci, 2016 Sep 13; 17(9). PMID: 27618037    Free PMC article.
The Value of Online Algorithms to Predict T-Cell Ligands Created by Genetic Variants.
Dyantha I van der Lee, Margot J Pont, J H Frederik Falkenburg, Marieke Griffioen.
PLoS One, 2016 Sep 13; 11(9). PMID: 27618304    Free PMC article.
MHC-multimer guided isolation of neoepitopes specific T cells as a potent-personalized cancer treatment strategy.
Roni Bareli, Cyrille J Cohen.
Oncoimmunology, 2016 Sep 14; 5(7). PMID: 27622017    Free PMC article.
Current tools for predicting cancer-specific T cell immunity.
David Gfeller, Michal Bassani-Sternberg, Julien Schmidt, Immanuel F Luescher.
Oncoimmunology, 2016 Sep 14; 5(7). PMID: 27622028    Free PMC article.
Immunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop.
Roch Houot, Philippe Gaulard, +18 authors, Daniel Olive.
Oncoimmunology, 2016 Sep 14; 5(7). PMID: 27622041    Free PMC article.
Adjuvant dendritic cell vaccination induces tumor-specific immune responses in the majority of stage III melanoma patients.
Steve Boudewijns, Kalijn F Bol, +19 authors, I Jolanda M de Vries.
Oncoimmunology, 2016 Sep 14; 5(7). PMID: 27622047    Free PMC article.
Biphasic function of TLR3 adjuvant on tumor and spleen dendritic cells promotes tumor T cell infiltration and regression in a vaccine therapy.
Masahiro Azuma, Yohei Takeda, +5 authors, Tsukasa Seya.
Oncoimmunology, 2016 Sep 14; 5(8). PMID: 27622060    Free PMC article.
Ipilimumab administered to metastatic melanoma patients who progressed after dendritic cell vaccination.
Steve Boudewijns, Rutger H T Koornstra, +8 authors, Winald R Gerritsen.
Oncoimmunology, 2016 Sep 14; 5(8). PMID: 27622070    Free PMC article.
Reevaluating stereotactic radiosurgery for glioblastoma: new potential for targeted dose-escalation.
Ted K Yanagihara, Heva J Saadatmand, Tony J C Wang.
J Neurooncol, 2016 Sep 16; 130(3). PMID: 27632018
Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration.
Marcel Smid, F Germán Rodríguez-González, +44 authors, John W M Martens.
Nat Commun, 2016 Sep 27; 7. PMID: 27666519    Free PMC article.
The efficacy and safety of anti-PD-1/PD-L1 antibodies for treatment of advanced or refractory cancers: a meta-analysis.
Tengfei Zhang, Jing Xie, +13 authors, Yi Zhang.
Oncotarget, 2016 Sep 30; 7(45). PMID: 27683031    Free PMC article.
Immunogenomics of Hypermutated Glioblastoma: A Patient with Germline POLE Deficiency Treated with Checkpoint Blockade Immunotherapy.
Tanner M Johanns, Christopher A Miller, +10 authors, Gavin P Dunn.
Cancer Discov, 2016 Nov 04; 6(11). PMID: 27683556    Free PMC article.
Highly Cited.
Tumor Infiltrating Lymphocytes Affect the Outcome of Patients with Operable Triple-Negative Breast Cancer in Combination with Mutated Amino Acid Classes.
Vassiliki Kotoula, Sotiris Lakis, +18 authors, George Fountzilas.
PLoS One, 2016 Sep 30; 11(9). PMID: 27685159    Free PMC article.
Profiling cancer testis antigens in non-small-cell lung cancer.
Dijana Djureinovic, Björn M Hallström, +19 authors, Patrick Micke.
JCI Insight, 2016 Oct 05; 1(10). PMID: 27699219    Free PMC article.
Claudin-low bladder tumors are immune infiltrated and actively immune suppressed.
Jordan Kardos, Shengjie Chai, +8 authors, Benjamin G Vincent.
JCI Insight, 2016 Oct 05; 1(3). PMID: 27699256    Free PMC article.
Highly Cited.
Recent advances in T-cell engineering for use in immunotherapy.
Preeti Sharma, David M Kranz.
F1000Res, 2016 Oct 06; 5. PMID: 27703664    Free PMC article.
Simul-seq: combined DNA and RNA sequencing for whole-genome and transcriptome profiling.
Jason A Reuter, Damek V Spacek, Reetesh K Pai, Michael P Snyder.
Nat Methods, 2016 Nov 01; 13(11). PMID: 27723755    Free PMC article.
Rekindling cancer vaccines.
Malorye Allison Branca.
Nat Biotechnol, 2016 Oct 12; 34(10). PMID: 27727216
Biomarkers for immune therapy in colorectal cancer: mismatch-repair deficiency and others.
Manojkumar Bupathi, Christina Wu.
J Gastrointest Oncol, 2016 Oct 18; 7(5). PMID: 27747085    Free PMC article.
Immunogenic cell death in cancer and infectious disease.
Lorenzo Galluzzi, Aitziber Buqué, +2 authors, Guido Kroemer.
Nat Rev Immunol, 2016 Nov 01; 17(2). PMID: 27748397
Highly Cited. Review.
Neoantigens in immunotherapy and personalized vaccines: Implications for head and neck squamous cell carcinoma.
Paul Zolkind, Gavin P Dunn, +3 authors, Ravindra Uppaluri.
Oral Oncol, 2016 Oct 19; 71. PMID: 27751760    Free PMC article.
Effective induction of cytotoxic T cells recognizing an epitope peptide derived from hypoxia-inducible protein 2 (HIG2) in patients with metastatic renal cell carcinoma.
Wataru Obara, Takashi Karashima, +9 authors, Tomoaki Fujioka.
Cancer Immunol Immunother, 2016 Oct 21; 66(1). PMID: 27757561    Free PMC article.
Radiotherapy: Changing the Game in Immunotherapy.
Sandra Demaria, C Norman Coleman, Silvia C Formenti.
Trends Cancer, 2016 Oct 25; 2(6). PMID: 27774519    Free PMC article.
Highly Cited. Review.
Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment.
Hanna Starobinets, Jordan Ye, +6 authors, Jayanta Debnath.
J Clin Invest, 2016 Oct 25; 126(12). PMID: 27775547    Free PMC article.
Aptamers: A New Technological Platform in Cancer Immunotherapy.
Fernando Pastor.
Pharmaceuticals (Basel), 2016 Oct 27; 9(4). PMID: 27783034    Free PMC article.
Is there a role for therapeutic cancer vaccines in the age of checkpoint inhibitors?
Robert O Dillman.
Hum Vaccin Immunother, 2016 Nov 04; 13(3). PMID: 27808593    Free PMC article.
Generation of T cell effectors using tumor cell-loaded dendritic cells for adoptive T cell therapy.
Katerina Vavrova, Petra Vrabcova, +2 authors, Rudolf Horvath.
Med Oncol, 2016 Nov 05; 33(12). PMID: 27812850
Immune Responses to Epidermal Growth Factor Receptor (EGFR) and Their Application for Cancer Treatment.
Tetsuro Sasada, Koichi Azuma, Junya Ohtake, Yuki Fujimoto.
Front Pharmacol, 2016 Nov 12; 7. PMID: 27833557    Free PMC article.
Gene-expression profiling to predict responsiveness to immunotherapy.
N B Jamieson, A V Maker.
Cancer Gene Ther, 2016 Nov 12; 24(3). PMID: 27834354    Free PMC article.
Emerging role of immunotherapy in urothelial carcinoma-Immunobiology/biomarkers.
Randy F Sweis, Matthew D Galsky.
Urol Oncol, 2016 Nov 12; 34(12). PMID: 27836246    Free PMC article.
MHC class I-associated peptides derive from selective regions of the human genome.
Hillary Pearson, Tariq Daouda, +10 authors, Claude Perreault.
J Clin Invest, 2016 Nov 15; 126(12). PMID: 27841757    Free PMC article.
Highly Cited.
High-throughput T cell receptor sequencing reveals distinct repertoires between tumor and adjacent non-tumor tissues in HBV-associated HCC.
Yunqing Chen, Ying Xu, +5 authors, Zhanhui Wang.
Oncoimmunology, 2016 Nov 18; 5(10). PMID: 27853640    Free PMC article.
Increased PD-L1 and T-cell infiltration in the presence of HLA class I expression in metastatic high-grade osteosarcoma: a rationale for T-cell-based immunotherapy.
Yayan T Sundara, Marie Kostine, +3 authors, Anne-Marie Cleton-Jansen.
Cancer Immunol Immunother, 2016 Nov 18; 66(1). PMID: 27853827    Free PMC article.
The challenges of tumor genetic diversity.
Edmund A Mroz, James W Rocco.
Cancer, 2016 Nov 20; 123(6). PMID: 27861749    Free PMC article.
Tumor vaccines and cellular immunotherapies.
John Nemunaitis, Neil Senzer, Leah Plato.
Ann Transl Med, 2016 Nov 22; 4(Suppl 1). PMID: 27867992    Free PMC article.
Next generation predictive biomarkers for immune checkpoint inhibition.
Yulian Khagi, Razelle Kurzrock, Sandip Pravin Patel.
Cancer Metastasis Rev, 2016 Nov 23; 36(1). PMID: 27873079    Free PMC article.
Improved proliferation of antigen-specific cytolytic T lymphocytes using a multimodal nanovaccine.
Bo Li, Michael Siuta, +10 authors, Wellington Pham.
Int J Nanomedicine, 2016 Nov 30; 11. PMID: 27895483    Free PMC article.
Recent advances in T-cell immunotherapy for haematological malignancies.
Rayne H Rouce, Sandhya Sharma, Mai Huynh, Helen E Heslop.
Br J Haematol, 2016 Nov 30; 176(5). PMID: 27897332    Free PMC article.
Transcriptome and long noncoding RNA sequencing of three extracellular vesicle subtypes released from the human colon cancer LIM1863 cell line.
Maoshan Chen, Rong Xu, +6 authors, Richard J Simpson.
Sci Rep, 2016 Dec 06; 6. PMID: 27917920    Free PMC article.
Predictive biomarkers for checkpoint inhibitor-based immunotherapy.
Geoffrey T Gibney, Louis M Weiner, Michael B Atkins.
Lancet Oncol, 2016 Dec 08; 17(12). PMID: 27924752    Free PMC article.
Highly Cited. Review.
Prediction and prioritization of neoantigens: integration of RNA sequencing data with whole-exome sequencing.
Takahiro Karasaki, Kazuhiro Nagayama, +9 authors, Kazuhiro Kakimi.
Cancer Sci, 2016 Dec 14; 108(2). PMID: 27960040    Free PMC article.
Photodynamic Therapy Mediated by Nontoxic Core-Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer.
Xiaopin Duan, Christina Chan, +3 authors, Wenbin Lin.
J Am Chem Soc, 2016 Dec 16; 138(51). PMID: 27976881    Free PMC article.
Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease.
Hanne Astrid Eide, Ann Rita Halvorsen, +8 authors, Åslaug Helland.
Clin Transl Immunology, 2016 Dec 19; 5(11). PMID: 27990285    Free PMC article.
Immuno-Oncology: The Third Paradigm in Early Drug Development.
Juan Martin-Liberal, Cinta Hierro, Maria Ochoa de Olza, Jordi Rodon.
Target Oncol, 2016 Dec 21; 12(2). PMID: 27995439
Identification of immunotherapeutic targets by genomic profiling of rectal NET metastases.
Zeynep Koşaloğlu, Inka Zörnig, +7 authors, Dirk Jäger.
Oncoimmunology, 2016 Dec 22; 5(11). PMID: 27999735    Free PMC article.
Reprogramming of TLR7 signaling enhances antitumor NK and cytotoxic T cell responses.
Christian Hotz, Marina Treinies, +7 authors, Carole Bourquin.
Oncoimmunology, 2016 Dec 22; 5(11). PMID: 27999742    Free PMC article.
Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells.
Jon Amund Kyte, Steinar Aamdal, +6 authors, Gunnar Kvalheim.
Oncoimmunology, 2016 Dec 22; 5(11). PMID: 27999747    Free PMC article.
Engaging Natural Killer T Cells as 'Universal Helpers' for Vaccination.
Mary Speir, Ian F Hermans, Robert Weinkove.
Drugs, 2016 Dec 23; 77(1). PMID: 28005229
Designer vaccine nanodiscs for personalized cancer immunotherapy.
Rui Kuai, Lukasz J Ochyl, +2 authors, James J Moon.
Nat Mater, 2016 Dec 27; 16(4). PMID: 28024156    Free PMC article.
Highly Cited.
Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.
Mohammadreza Movahedin, Teresa M Brooks, +3 authors, Cory L Brooks.
Glycobiology, 2016 Dec 28; 27(7). PMID: 28025250    Free PMC article.
Dendritic cell-based immunotherapy.
Rachel L Sabado, Sreekumar Balan, Nina Bhardwaj.
Cell Res, 2016 Dec 28; 27(1). PMID: 28025976    Free PMC article.
Highly Cited. Review.
Evolution of Neoantigen Landscape during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer.
Valsamo Anagnostou, Kellie N Smith, +26 authors, Victor E Velculescu.
Cancer Discov, 2016 Dec 30; 7(3). PMID: 28031159    Free PMC article.
Highly Cited.
IL-33 acts as a foe to MIA PaCa-2 pancreatic cancer.
Yujiang Fang, Lei Zhao, +8 authors, Michael B Nicholl.
Med Oncol, 2017 Jan 07; 34(2). PMID: 28058630
T cell receptor repertoire usage in cancer as a surrogate marker for immune responses.
David Schrama, Cathrin Ritter, Jürgen C Becker.
Semin Immunopathol, 2017 Jan 12; 39(3). PMID: 28074285
Coevolution of Leukemia and Host Immune Cells in Chronic Lymphocytic Leukemia.
Noelia Purroy, Catherine J Wu.
Cold Spring Harb Perspect Med, 2017 Jan 18; 7(4). PMID: 28096240    Free PMC article.
Reactivation of dormant anti-tumor immunity - a clinical perspective of therapeutic immune checkpoint modulation.
Richard Greil, Evelyn Hutterer, Tanja Nicole Hartmann, Lisa Pleyer.
Cell Commun Signal, 2017 Jan 20; 15(1). PMID: 28100240    Free PMC article.
Elements of cancer immunity and the cancer-immune set point.
Daniel S Chen, Ira Mellman.
Nature, 2017 Jan 20; 541(7637). PMID: 28102259
Highly Cited. Review.
Genetically Modified T-Cell-Based Adoptive Immunotherapy in Hematological Malignancies.
Baixin Ye, Creed M Stary, +5 authors, Xiaoxing Xiong.
J Immunol Res, 2017 Jan 25; 2017. PMID: 28116322    Free PMC article.
Rapid tumor regression in an Asian lung cancer patient following personalized neo-epitope peptide vaccination.
Fenge Li, Caixia Chen, +7 authors, Gregory Lizée.
Oncoimmunology, 2017 Jan 27; 5(12). PMID: 28123873    Free PMC article.
Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma.
Isabel Poschke, Marta Faryna, +19 authors, Rienk Offringa.
Oncoimmunology, 2017 Jan 27; 5(12). PMID: 28123878    Free PMC article.
T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy.
Jon Amund Kyte, Gustav Gaudernack, +7 authors, Martin Pule.
Oncoimmunology, 2017 Jan 27; 5(12). PMID: 28123886    Free PMC article.
The development of dendritic cell vaccine-based immunotherapies for glioblastoma.
David A Reardon, Duane A Mitchell.
Semin Immunopathol, 2017 Feb 01; 39(2). PMID: 28138787
Tumor regulation of the tissue environment in the liver.
Tobias Eggert, Tim F Greten.
Pharmacol Ther, 2017 Feb 09; 173. PMID: 28167218    Free PMC article.
Historical Evolution of Second-Line Therapy in Non-Small Cell Lung Cancer.
Chiara Lazzari, Alessandra Bulotta, +5 authors, Vanesa Gregorc.
Front Med (Lausanne), 2017 Feb 09; 4. PMID: 28168189    Free PMC article.
Translation and Clinical Development of Bispecific T-cell Engaging Antibodies for Cancer Treatment.
T Yuraszeck, S Kasichayanula, J E Benjamin.
Clin Pharmacol Ther, 2017 Feb 10; 101(5). PMID: 28182247    Free PMC article.
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy.
Padmanee Sharma, Siwen Hu-Lieskovan, Jennifer A Wargo, Antoni Ribas.
Cell, 2017 Feb 12; 168(4). PMID: 28187290    Free PMC article.
Highly Cited. Review.
The Principles of Engineering Immune Cells to Treat Cancer.
Wendell A Lim, Carl H June.
Cell, 2017 Feb 12; 168(4). PMID: 28187291    Free PMC article.
Highly Cited. Review.
Adoptive Transfer of Invariant NKT Cells as Immunotherapy for Advanced Melanoma: A Phase I Clinical Trial.
Mark A Exley, Phillip Friedlander, +15 authors, Steven P Balk.
Clin Cancer Res, 2017 Feb 15; 23(14). PMID: 28193627    Free PMC article.
Highly Cited.
The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy.
Andrew M K Law, Elgene Lim, Christopher J Ormandy, David Gallego-Ortega.
Endocr Relat Cancer, 2017 Feb 15; 24(4). PMID: 28193698    Free PMC article.
Tumor-infiltrating lymphocyte composition, organization and PD-1/ PD-L1 expression are linked in breast cancer.
Laurence Buisseret, Soizic Garaud, +14 authors, Karen Willard-Gallo.
Oncoimmunology, 2017 Feb 16; 6(1). PMID: 28197375    Free PMC article.
Highly Cited.
Identification of inhibitors of myeloid-derived suppressor cells activity through phenotypic chemical screening.
Matthias Schröder, Simone Loos, +5 authors, Lee Kim Swee.
Oncoimmunology, 2017 Feb 16; 6(1). PMID: 28197378    Free PMC article.
Hypermutation signature reveals a slippage and realignment model of translesion synthesis by Rev3 polymerase in cisplatin-treated yeast.
Romulo Segovia, Yaoqing Shen, +2 authors, Peter C Stirling.
Proc Natl Acad Sci U S A, 2017 Feb 23; 114(10). PMID: 28223526    Free PMC article.
Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction.
Jennifer G Abelin, Derin B Keskin, +12 authors, Catherine J Wu.
Immunity, 2017 Feb 24; 46(2). PMID: 28228285    Free PMC article.
Highly Cited.
The biology of uveal melanoma.
Adriana Amaro, Rosaria Gangemi, +4 authors, Ulrich Pfeffer.
Cancer Metastasis Rev, 2017 Feb 24; 36(1). PMID: 28229253    Free PMC article.
Lipopolyplex potentiates anti-tumor immunity of mRNA-based vaccination.
Stefano Persano, Maria L Guevara, +4 authors, Haifa Shen.
Biomaterials, 2017 Feb 24; 125. PMID: 28231510    Free PMC article.
Combination immunotherapy: a road map.
Patrick A Ott, F Stephen Hodi, +2 authors, Jedd D Wolchok.
J Immunother Cancer, 2017 Feb 28; 5. PMID: 28239469    Free PMC article.
Highly Cited. Review.
Transient Treg depletion enhances therapeutic anti-cancer vaccination.
Scott A Fisher, Wayne J Aston, +11 authors, Richard A Lake.
Immun Inflamm Dis, 2017 Mar 03; 5(1). PMID: 28250921    Free PMC article.
Prognostic significance of interferon regulating factor 4 (IRF4) in node-negative breast cancer.
Anne-Sophie Heimes, K Madjar, +9 authors, M Schmidt.
J Cancer Res Clin Oncol, 2017 Mar 03; 143(7). PMID: 28251349
Using cancer genomics to guide clinical decisions.
Mark E Burkard, Dustin A Deming, Josh Lauring.
Cancer, 2017 Mar 03; 123(8). PMID: 28253425    Free PMC article.
Serine Proteases Enhance Immunogenic Antigen Presentation on Lung Cancer Cells.
Haley L Peters, Satyendra C Tripathi, +18 authors, Jeffrey J Molldrem.
Cancer Immunol Res, 2017 Mar 04; 5(4). PMID: 28254787    Free PMC article.
TAM receptor tyrosine kinases as emerging targets of innate immune checkpoint blockade for cancer therapy.
Yemsratch T Akalu, Carla V Rothlin, Sourav Ghosh.
Immunol Rev, 2017 Mar 05; 276(1). PMID: 28258690    Free PMC article.
Precision medicine driven by cancer systems biology.
Fabian V Filipp.
Cancer Metastasis Rev, 2017 Mar 08; 36(1). PMID: 28265786    Free PMC article.
Cytokine biomarkers to predict antitumor responses to nivolumab suggested in a phase 2 study for advanced melanoma.
Naoya Yamazaki, Yoshio Kiyohara, +11 authors, Hideaki Tahara.
Cancer Sci, 2017 Mar 08; 108(5). PMID: 28266140    Free PMC article.
Renal cell carcinoma.
James J Hsieh, Mark P Purdue, +6 authors, Vincenzo Ficarra.
Nat Rev Dis Primers, 2017 Mar 10; 3. PMID: 28276433    Free PMC article.
Highly Cited. Review.
[Immunotherapy of cancer with checkpoint inhibitors : Not only in malignant melanoma].
A Neubauer.
Internist (Berl), 2017 Mar 18; 58(4). PMID: 28303311
Mechanistic and pharmacologic insights on immune checkpoint inhibitors.
Randy F Sweis, Jason J Luke.
Pharmacol Res, 2017 Mar 23; 120. PMID: 28323141    Free PMC article.
Synthetic nanovaccines for immunotherapy.
Min Luo, Layla Z Samandi, +2 authors, Jinming Gao.
J Control Release, 2017 Mar 25; 263. PMID: 28336379    Free PMC article.
Detecting truly clonal alterations from multi-region profiling of tumours.
Benjamin Werner, Arne Traulsen, Andrea Sottoriva, David Dingli.
Sci Rep, 2017 Mar 28; 7. PMID: 28344344    Free PMC article.
Loss of tapasin in human lung and colon cancer cells and escape from tumor-associated antigen-specific CTL recognition.
Yosuke Shionoya, Takayuki Kanaseki, +12 authors, Toshihiko Torigoe.
Oncoimmunology, 2017 Mar 28; 6(2). PMID: 28344889    Free PMC article.
Integrated analysis of somatic mutations and immune microenvironment in malignant pleural mesothelioma.
Kazuma Kiyotani, Jae-Hyun Park, +5 authors, Wickii T Vigneswaran.
Oncoimmunology, 2017 Mar 28; 6(2). PMID: 28344893    Free PMC article.
Stratification of Pancreatic Ductal Adenocarcinoma: Combinatorial Genetic, Stromal, and Immunologic Markers.
Erik S Knudsen, Paris Vail, +9 authors, Agnieszka K Witkiewicz.
Clin Cancer Res, 2017 Mar 30; 23(15). PMID: 28348045    Free PMC article.
Highly Cited.
Cancer Immunotherapy: Whence and Whither.
Peter J Stambrook, John Maher, Farzin Farzaneh.
Mol Cancer Res, 2017 Mar 31; 15(6). PMID: 28356330    Free PMC article.
Biomarkers to predict prognosis and response to checkpoint inhibitors.
Takeshi Yuasa, Hitoshi Masuda, +2 authors, Junji Yonese.
Int J Clin Oncol, 2017 Apr 07; 22(4). PMID: 28382562    Free PMC article.
Molecularly targeted therapies in cancer: a guide for the nuclear medicine physician.
S Lheureux, C Denoyelle, +2 authors, F M Mottaghy.
Eur J Nucl Med Mol Imaging, 2017 Apr 12; 44(Suppl 1). PMID: 28396911    Free PMC article.
Antibody Engineering for Pursuing a Healthier Future.
Abdullah F U H Saeed, Rongzhi Wang, Sumei Ling, Shihua Wang.
Front Microbiol, 2017 Apr 13; 8. PMID: 28400756    Free PMC article.
Resistance to immunotherapy: clouds in a bright sky.
Gérard Milano.
Invest New Drugs, 2017 Apr 13; 35(5). PMID: 28401366
Breaking the crosstalk of the cellular tumorigenic network: Hypothesis for addressing resistances to targeted therapies in advanced NSCLC.
Stefan Langhammer, Joachim Scheerer.
Oncotarget, 2017 Apr 14; 8(26). PMID: 28402937    Free PMC article.
Human papilloma virus load and PD-1/PD-L1, CD8+ and FOXP3 in anal cancer patients treated with chemoradiotherapy: Rationale for immunotherapy.
Panagiotis Balermpas, Daniel Martin, +5 authors, Franz Rödel.
Oncoimmunology, 2017 Apr 14; 6(3). PMID: 28405521    Free PMC article.
Cellular determinants and microenvironmental regulation of prostate cancer metastasis.
Kiera Rycaj, Hangwen Li, +2 authors, Dean G Tang.
Semin Cancer Biol, 2017 Apr 15; 44. PMID: 28408152    Free PMC article.
Applied Cancer Immunogenomics: Leveraging Neoantigen Discovery in Glioblastoma.
Tanner M Johanns, Gavin P Dunn.
Cancer J, 2017 Apr 15; 23(2). PMID: 28410300    Free PMC article.
Antigen Discovery and Therapeutic Targeting in Hematologic Malignancies.
David A Braun, Catherine J Wu.
Cancer J, 2017 Apr 15; 23(2). PMID: 28410299    Free PMC article.
Multi-omics study revealing the complexity and spatial heterogeneity of tumor-infiltrating lymphocytes in primary liver carcinoma.
Lijun Shi, Yang Zhang, +6 authors, Shujun Cheng.
Oncotarget, 2017 Apr 20; 8(21). PMID: 28422742    Free PMC article.
Long-term complete remission with Ipilimumab in metastatic castrate-resistant prostate cancer: case report of two patients.
Luc Cabel, Elika Loir, +6 authors, Karim Fizazi.
J Immunother Cancer, 2017 Apr 22; 5. PMID: 28428880    Free PMC article.
Differential intratumoral distributions of CD8 and CD163 immune cells as prognostic biomarkers in breast cancer.
Sotirios P Fortis, Michael Sofopoulos, +9 authors, Constantin N Baxevanis.
J Immunother Cancer, 2017 Apr 22; 5. PMID: 28428887    Free PMC article.
Increasing the safety and efficacy of chimeric antigen receptor T cell therapy.
Hua Li, Yangbing Zhao.
Protein Cell, 2017 Apr 24; 8(8). PMID: 28434147    Free PMC article.
Control of immune cell entry through the tumour vasculature: a missing link in optimising melanoma immunotherapy?
Lih Yin Tan, Carmela Martini, +3 authors, Lisa M Ebert.
Clin Transl Immunology, 2017 Apr 25; 6(3). PMID: 28435677    Free PMC article.
A STING-activating nanovaccine for cancer immunotherapy.
Min Luo, Hua Wang, +13 authors, Jinming Gao.
Nat Nanotechnol, 2017 Apr 25; 12(7). PMID: 28436963    Free PMC article.
Highly Cited.
Plasmodium parasite as an effective hepatocellular carcinoma antigen glypican-3 delivery vector.
Quan Liu, Yijun Yang, +8 authors, Xiaoping Chen.
Oncotarget, 2017 Apr 28; 8(15). PMID: 28445973    Free PMC article.
Radiation improves antitumor effect of immune checkpoint inhibitor in murine hepatocellular carcinoma model.
Kyoung-Jin Kim, Ji-Hye Kim, +3 authors, Jinsil Seong.
Oncotarget, 2017 May 04; 8(25). PMID: 28465485    Free PMC article.
Sarcoma Eradication by Doxorubicin and Targeted TNF Relies upon CD8+ T-cell Recognition of a Retroviral Antigen.
Philipp Probst, Janine Kopp, +4 authors, Dario Neri.
Cancer Res, 2017 May 10; 77(13). PMID: 28484076    Free PMC article.
TSNAD: an integrated software for cancer somatic mutation and tumour-specific neoantigen detection.
Zhan Zhou, Xingzheng Lyu, +6 authors, Shuqing Chen.
R Soc Open Sci, 2017 May 10; 4(4). PMID: 28484631    Free PMC article.
In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy.
Sean P Arlauckas, Christopher S Garris, +9 authors, Mikael J Pittet.
Sci Transl Med, 2017 May 12; 9(389). PMID: 28490665    Free PMC article.
Highly Cited.
Current status of chimeric antigen receptor engineered T cell-based and immune checkpoint blockade-based cancer immunotherapies.
Upendra P Hegde, Bijay Mukherji.
Cancer Immunol Immunother, 2017 May 13; 66(9). PMID: 28497159    Free PMC article.
Preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma.
Abhishek D Garg, Lien Vandenberk, +5 authors, Patrizia Agostinis.
Oncoimmunology, 2017 May 17; 6(4). PMID: 28507806    Free PMC article.
Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy.
Sacha Gnjatic, Vincenzo Bronte, +13 authors, Lisa H Butterfield.
J Immunother Cancer, 2017 May 19; 5. PMID: 28515944    Free PMC article.
Highly Cited. Review.
HLA-A24 ligandome analysis of colon and lung cancer cells identifies a novel cancer-testis antigen and a neoantigen that elicits specific and strong CTL responses.
Vitaly Kochin, Takayuki Kanaseki, +11 authors, Toshihiko Torigoe.
Oncoimmunology, 2017 May 24; 6(4). PMID: 28533942    Free PMC article.
In silico and cell-based analyses reveal strong divergence between prediction and observation of T-cell-recognized tumor antigen T-cell epitopes.
Julien Schmidt, Philippe Guillaume, +3 authors, Immanuel Luescher.
J Biol Chem, 2017 May 26; 292(28). PMID: 28536262    Free PMC article.
Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1.
Anita Sveen, Bjarne Johannessen, +13 authors, Ragnhild A Lothe.
Genome Med, 2017 May 26; 9(1). PMID: 28539123    Free PMC article.
Quantitative Mass Spectrometry Analysis of PD-L1 Protein Expression, N-glycosylation and Expression Stoichiometry with PD-1 and PD-L2 in Human Melanoma.
Carlos A Morales-Betanzos, Hyoungjoo Lee, +4 authors, Daniel C Liebler.
Mol Cell Proteomics, 2017 May 27; 16(10). PMID: 28546465    Free PMC article.
Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy.
Sandra M Kallert, Stephanie Darbre, +12 authors, Daniel D Pinschewer.
Nat Commun, 2017 May 27; 8. PMID: 28548102    Free PMC article.
Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.
Hong Jiang, Yisel Rivera-Molina, +8 authors, Juan Fueyo.
Cancer Res, 2017 Jun 02; 77(14). PMID: 28566332    Free PMC article.
Highly Cited.
Immunotherapy for Breast Cancer: What Are We Missing?
Robert H Vonderheide, Susan M Domchek, Amy S Clark.
Clin Cancer Res, 2017 Jun 03; 23(11). PMID: 28572258    Free PMC article.
Highly Cited.
Manufacture of CAR-T cells in the body.
Johanna Olweus.
Nat Biotechnol, 2017 Jun 08; 35(6). PMID: 28591119
Elastic-Fluid Model for DNA Damage and Mutation from Nuclear Fluid Segregation Due to Cell Migration.
Rachel R Bennett, Charlotte R Pfeifer, +3 authors, Andrea J Liu.
Biophys J, 2017 Jun 08; 112(11). PMID: 28591600    Free PMC article.
Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer.
Emma Nolan, Peter Savas, +13 authors, Geoffrey J Lindeman.
Sci Transl Med, 2017 Jun 09; 9(393). PMID: 28592566    Free PMC article.
Highly Cited.
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.
Dung T Le, Jennifer N Durham, +43 authors, Luis A Diaz.
Science, 2017 Jun 10; 357(6349). PMID: 28596308    Free PMC article.
Highly Cited.
Modulating Both Tumor Cell Death and Innate Immunity Is Essential for Improving Radiation Therapy Effectiveness.
Qiuji Wu, Awatef Allouch, +4 authors, Jean-Luc Perfettini.
Front Immunol, 2017 Jun 13; 8. PMID: 28603525    Free PMC article.
CloudNeo: a cloud pipeline for identifying patient-specific tumor neoantigens.
Preeti Bais, Sandeep Namburi, +2 authors, Jeffrey H Chuang.
Bioinformatics, 2017 Jun 13; 33(19). PMID: 28605406    Free PMC article.
Metabolism shapes the tumor microenvironment.
Miguel Reina-Campos, Jorge Moscat, Maria Diaz-Meco.
Curr Opin Cell Biol, 2017 Jun 13; 48. PMID: 28605656    Free PMC article.
Cancer in primary immunodeficiency diseases: Cancer incidence in the United States Immune Deficiency Network Registry.
Paul C Mayor, Kevin H Eng, +13 authors, Brahm H Segal.
J Allergy Clin Immunol, 2017 Jun 14; 141(3). PMID: 28606585    Free PMC article.
Highly Cited.
Pembrolizumab in cervical cancer: latest evidence and clinical usefulness.
Edith Borcoman, Christophe Le Tourneau.
Ther Adv Med Oncol, 2017 Jun 14; 9(6). PMID: 28607581    Free PMC article.
Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition.
Sebastian Peer, Gottfried Baier, Thomas Gruber.
Oncotarget, 2017 Jun 15; 8(26). PMID: 28611299    Free PMC article.
Cytomegalovirus vector expressing RAE-1γ induces enhanced anti-tumor capacity of murine CD8+ T cells.
Tihana Tršan, Kristina Vuković, +8 authors, Stipan Jonjić.
Eur J Immunol, 2017 Jun 15; 47(8). PMID: 28612942    Free PMC article.
Breast Cancer Neoantigens Can Induce CD8+ T-Cell Responses and Antitumor Immunity.
Xiuli Zhang, Samuel Kim, +19 authors, William E Gillanders.
Cancer Immunol Res, 2017 Jun 18; 5(7). PMID: 28619968    Free PMC article.
Phase II Study of Adjuvant Immunotherapy with the CSF-470 Vaccine Plus Bacillus Calmette-Guerin Plus Recombinant Human Granulocyte Macrophage-Colony Stimulating Factor vs Medium-Dose Interferon Alpha 2B in Stages IIB, IIC, and III Cutaneous Melanoma Patients: A Single Institution, Randomized Study.
José Mordoh, María Betina Pampena, +11 authors, María Marcela Barrio.
Front Immunol, 2017 Jun 18; 8. PMID: 28620382    Free PMC article.
Harnessing the immune response to target tumors.
Luisa Manning, John Nemunaitis.
F1000Res, 2017 Jun 18; 6. PMID: 28620466    Free PMC article.
DNA Damage and Repair Biomarkers of Immunotherapy Response.
Kent W Mouw, Michael S Goldberg, Panagiotis A Konstantinopoulos, Alan D D'Andrea.
Cancer Discov, 2017 Jun 21; 7(7). PMID: 28630051    Free PMC article.
Highly Cited. Review.
SLC45A2: A Melanoma Antigen with High Tumor Selectivity and Reduced Potential for Autoimmune Toxicity.
Jungsun Park, Amjad H Talukder, +17 authors, Cassian Yee.
Cancer Immunol Res, 2017 Jun 21; 5(8). PMID: 28630054    Free PMC article.
Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System.
Stefano Santaguida, Amelia Richardson, +7 authors, Angelika Amon.
Dev Cell, 2017 Jun 21; 41(6). PMID: 28633018    Free PMC article.
Highly Cited.
Vaccination with High-Affinity Epitopes Impairs Antitumor Efficacy by Increasing PD-1 Expression on CD8+ T Cells.
Christopher D Zahm, Viswa T Colluru, Douglas G McNeel.
Cancer Immunol Res, 2017 Jun 22; 5(8). PMID: 28634215    Free PMC article.
Immune Checkpoints as a Target for Colorectal Cancer Treatment.
Alessandro Passardi, Matteo Canale, Martina Valgiusti, Paola Ulivi.
Int J Mol Sci, 2017 Jun 22; 18(6). PMID: 28635639    Free PMC article.
Polyelectrolyte-Enrobed Cancer Cells in View of Personalized Immune-Therapy.
Lien Lybaert, Keun Ah Ryu, +5 authors, Bruno G De Geest.
Adv Sci (Weinh), 2017 Jun 24; 4(6). PMID: 28638786    Free PMC article.
Intratumorally injected pro-inflammatory allogeneic dendritic cells as immune enhancers: a first-in-human study in unfavourable risk patients with metastatic renal cell carcinoma.
Anna Laurell, Maria Lönnemark, +7 authors, Alex Karlsson-Parra.
J Immunother Cancer, 2017 Jun 24; 5. PMID: 28642820    Free PMC article.
Cytokines in immunogenic cell death: Applications for cancer immunotherapy.
Anne Showalter, Arati Limaye, +4 authors, Annette R Khaled.
Cytokine, 2017 Jun 27; 97. PMID: 28648866    Free PMC article.
Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy.
Yuanzeng Min, Kyle C Roche, +12 authors, Andrew Z Wang.
Nat Nanotechnol, 2017 Jun 27; 12(9). PMID: 28650437    Free PMC article.
Highly Cited.
Monitoring immune-checkpoint blockade: response evaluation and biomarker development.
Mizuki Nishino, Nikhil H Ramaiya, Hiroto Hatabu, F Stephen Hodi.
Nat Rev Clin Oncol, 2017 Jun 28; 14(11). PMID: 28653677    Free PMC article.
Highly Cited. Review.
Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling.
Lunyi Li, Xingdong Guo, +6 authors, Chenqi Xu.
Proc Natl Acad Sci U S A, 2017 Jul 01; 114(29). PMID: 28659468    Free PMC article.
The calreticulin (CALR) exon 9 mutations are promising targets for cancer immune therapy.
M O Holmström, E Martinenaite, +8 authors, M H Andersen.
Leukemia, 2017 Jul 06; 32(2). PMID: 28676668
An immunogenic personal neoantigen vaccine for patients with melanoma.
Patrick A Ott, Zhuting Hu, +37 authors, Catherine J Wu.
Nature, 2017 Jul 06; 547(7662). PMID: 28678778    Free PMC article.
Highly Cited.
Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.
Qianghu Wang, Baoli Hu, +31 authors, Roel G W Verhaak.
Cancer Cell, 2017 Jul 12; 32(1). PMID: 28697342    Free PMC article.
Highly Cited.
A perspective on the impact of radiation therapy on the immune rheostat.
William H McBride, Ekambaram Ganapathy, +3 authors, Dörthe Schaue.
Br J Radiol, 2017 Jul 15; 90(1078). PMID: 28707537    Free PMC article.
Ex Vivo PD-L1/PD-1 Pathway Blockade Reverses Dysfunction of Circulating CEA-Specific T Cells in Pancreatic Cancer Patients.
Yuan Chen, Shao-An Xue, +3 authors, Emma C Morris.
Clin Cancer Res, 2017 Jul 16; 23(20). PMID: 28710313    Free PMC article.
Identification of trunk mutations in gastric carcinoma: a case study.
Zhan Zhou, Shanshan Wu, +7 authors, Shuqing Chen.
BMC Med Genomics, 2017 Jul 19; 10(1). PMID: 28716121    Free PMC article.
Potency-matched Dual Cytokine-Antibody Fusion Proteins for Cancer Therapy.
Roberto De Luca, Alex Soltermann, +4 authors, Dario Neri.
Mol Cancer Ther, 2017 Jul 19; 16(11). PMID: 28716814    Free PMC article.
TCR-ligand dissociation rate is a robust and stable biomarker of CD8+ T cell potency.
Mathilde Allard, Barbara Couturaud, +7 authors, Nathalie Rufer.
JCI Insight, 2017 Jul 21; 2(14). PMID: 28724801    Free PMC article.
Targeting C-type lectin receptors: a high-carbohydrate diet for dendritic cells to improve cancer vaccines.
Dieke van Dinther, Dorian A Stolk, +3 authors, Joke M M den Haan.
J Leukoc Biol, 2017 Jul 22; 102(4). PMID: 28729358    Free PMC article.
A high-fidelity method for genomic sequencing of single somatic cells reveals a very high mutational burden.
Jan Vijg, Xiao Dong, Lei Zhang.
Exp Biol Med (Maywood), 2017 Jul 25; 242(13). PMID: 28737476    Free PMC article.
Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer.
Manav Korpal, Xiaoling Puyang, +36 authors, Ping Zhu.
Nat Commun, 2017 Jul 26; 8(1). PMID: 28740126    Free PMC article.
The immune contexture in cancer prognosis and treatment.
Wolf H Fridman, Laurence Zitvogel, Catherine Sautès-Fridman, Guido Kroemer.
Nat Rev Clin Oncol, 2017 Jul 26; 14(12). PMID: 28741618
Highly Cited. Review.
Heterogeneity of tumor-infiltrating lymphocytes ascribed to local immune status rather than neoantigens by multi-omics analysis of glioblastoma multiforme.
Lin Feng, Haipeng Qian, +8 authors, Kaitai Zhang.
Sci Rep, 2017 Aug 02; 7(1). PMID: 28761058    Free PMC article.
Toxicity and Immunogenicity in Murine Melanoma following Exposure to Physical Plasma-Derived Oxidants.
Sander Bekeschus, Katrin Rödder, +6 authors, Rajesh Kumar Gandhirajan.
Oxid Med Cell Longev, 2017 Aug 02; 2017. PMID: 28761621    Free PMC article.
Mogamulizumab for relapsed adult T-cell leukemia-lymphoma: Updated follow-up analysis of phase I and II studies.
Takashi Ishida, Atae Utsunomiya, +12 authors, Ryuzo Ueda.
Cancer Sci, 2017 Aug 05; 108(10). PMID: 28776876    Free PMC article.
Cancer Immunotherapy, Part 3: Challenges and Future Trends.
C Lee Ventola.
P T, 2017 Aug 07; 42(8). PMID: 28781505    Free PMC article.
Highly Cited.
Moving molecular subtypes to the clinic in gastric cancer.
Joseph Chao, Jeeyun Lee, Samuel J Klempner.
Transl Cancer Res, 2016 Jun 01; 5(Suppl 1). PMID: 28781963    Free PMC article.
Listening to each other: Infectious disease and cancer immunology.
Russell E Vance, Michael J Eichberg, Daniel A Portnoy, David H Raulet.
Sci Immunol, 2017 Aug 08; 2(7). PMID: 28783669    Free PMC article.
Adult-onset hyperinsulinaemic hypoglycaemia in clinical practice: diagnosis, aetiology and management.
Benjamin G Challis, Andrew S Powlson, +12 authors, Helen L Simpson.
Endocr Connect, 2017 Aug 09; 6(7). PMID: 28784625    Free PMC article.
Immunotherapy in Breast Cancer: the Emerging Role of PD-1 and PD-L1.
François Bertucci, Anthony Gonçalves.
Curr Oncol Rep, 2017 Aug 12; 19(10). PMID: 28799073
IL-18 receptor marks functional CD8+ T cells in non-small cell lung cancer.
Eleonora Timperi, Chiara Focaccetti, +11 authors, Vincenzo Barnaba.
Oncoimmunology, 2017 Aug 16; 6(7). PMID: 28811967    Free PMC article.
Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.
Alexandre Reuben, Christine N Spencer, +51 authors, Jennifer A Wargo.
NPJ Genom Med, 2017 Aug 19; 2. PMID: 28819565    Free PMC article.
Highly Cited.
Ultra-small iron-gallic acid coordination polymer nanoparticles for chelator-free labeling of 64Cu and multimodal imaging-guided photothermal therapy.
Qiutong Jin, Wenjun Zhu, +7 authors, Liang Cheng.
Nanoscale, 2017 Aug 22; 9(34). PMID: 28825066    Free PMC article.
Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression.
Cody J Warren, Joseph A Westrich, Koenraad Van Doorslaer, Dohun Pyeon.
Viruses, 2017 Aug 22; 9(8). PMID: 28825669    Free PMC article.
Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity.
Michal Bassani-Sternberg, Chloé Chong, +6 authors, David Gfeller.
PLoS Comput Biol, 2017 Aug 24; 13(8). PMID: 28832583    Free PMC article.
Highly Cited.
Targeting Cancer Stem Cells and Their Niche: Current Therapeutic Implications and Challenges in Pancreatic Cancer.
Jiangang Zhao, Jiahui Li, +6 authors, Yue Zhao.
Stem Cells Int, 2017 Aug 29; 2017. PMID: 28845161    Free PMC article.
Immuno-oncology Trial Endpoints: Capturing Clinically Meaningful Activity.
Valsamo Anagnostou, Mark Yarchoan, +6 authors, Patrick M Forde.
Clin Cancer Res, 2017 Sep 03; 23(17). PMID: 28864724    Free PMC article.
Personalized ex vivo multiple peptide enrichment and detection of T cells reactive to multiple tumor-associated antigens in prostate cancer patients.
Pavla Taborska, Dmitry Stakheev, +4 authors, Daniel Smrz.
Med Oncol, 2017 Sep 04; 34(10). PMID: 28866803
Effects of thymic selection on T cell recognition of foreign and tumor antigenic peptides.
Jason T George, David A Kessler, Herbert Levine.
Proc Natl Acad Sci U S A, 2017 Sep 07; 114(38). PMID: 28874554    Free PMC article.
Immunotherapy: Cancer vaccines on the move.
Jacques Banchereau, Karolina Palucka.
Nat Rev Clin Oncol, 2017 Sep 13; 15(1). PMID: 28895570
Targeting Neoantigens in Glioblastoma: An Overview of Cancer Immunogenomics and Translational Implications.
Tanner M Johanns, Jay A Bowman-Kirigin, Connor Liu, Gavin P Dunn.
Neurosurgery, 2017 Sep 14; 64(CN_suppl_1). PMID: 28899059    Free PMC article.
The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Fiyaz Mohammed, Daniel H Stones, +7 authors, Benjamin E Willcox.
Oncotarget, 2017 Sep 15; 8(33). PMID: 28903331    Free PMC article.
Bioengineering of Artificial Antigen Presenting Cells and Lymphoid Organs.
Chao Wang, Wujin Sun, +2 authors, Zhen Gu.
Theranostics, 2017 Sep 16; 7(14). PMID: 28912891    Free PMC article.
Genomic Analysis of Tumor Microenvironment Immune Types across 14 Solid Cancer Types: Immunotherapeutic Implications.
Yu-Pei Chen, Yu Zhang, +9 authors, Jun Ma.
Theranostics, 2017 Sep 16; 7(14). PMID: 28912897    Free PMC article.
Highly Cited.
Resistance to CTLA-4 checkpoint inhibition reversed through selective elimination of granulocytic myeloid cells.
Paul E Clavijo, Ellen C Moore, +6 authors, Clint T Allen.
Oncotarget, 2017 Sep 17; 8(34). PMID: 28915554    Free PMC article.
Checkpoint blockade immunotherapy reshapes the high-dimensional phenotypic heterogeneity of murine intratumoural neoantigen-specific CD8+ T cells.
M Fehlings, Y Simoni, +7 authors, E W Newell.
Nat Commun, 2017 Sep 17; 8(1). PMID: 28916749    Free PMC article.
The frequency of neoantigens per somatic mutation rather than overall mutational load or number of predicted neoantigens per se is a prognostic factor in ovarian clear cell carcinoma.
Hirokazu Matsushita, Kosei Hasegawa, +9 authors, Kazuhiro Kakimi.
Oncoimmunology, 2017 Sep 19; 6(8). PMID: 28920005    Free PMC article.
Targets for immunotherapy of liver cancer.
Tim F Greten, Bruno Sangro.
J Hepatol, 2017 Sep 20;. PMID: 28923358    Free PMC article.
High somatic mutation and neoantigen burden are correlated with decreased progression-free survival in multiple myeloma.
A Miller, Y Asmann, +7 authors, A K Stewart.
Blood Cancer J, 2017 Sep 25; 7(9). PMID: 28937974    Free PMC article.
Highly Cited.
Distribution of circulating tumor DNA in lung cancer: analysis of the primary lung and bone marrow along with the pulmonary venous and peripheral blood.
Taichiro Goto, Yosuke Hirotsu, +7 authors, Masao Omata.
Oncotarget, 2017 Sep 25; 8(35). PMID: 28938635    Free PMC article.
Toward Personalized Peptide-Based Cancer Nanovaccines: A Facile and Versatile Synthetic Approach.
Hamilton Kakwere, Elizabeth S Ingham, +6 authors, Katherine W Ferrara.
Bioconjug Chem, 2017 Sep 29; 28(11). PMID: 28956907    Free PMC article.
Nanomaterials for cancer immunotherapy.
Wantong Song, Sara N Musetti, Leaf Huang.
Biomaterials, 2017 Sep 30; 148. PMID: 28961532    Free PMC article.
Immunomodulatory Monoclonal Antibodies in Combined Immunotherapy Trials for Cutaneous Melanoma.
Mariana Aris, José Mordoh, María Marcela Barrio.
Front Immunol, 2017 Oct 04; 8. PMID: 28970830    Free PMC article.
Hypermutated Circulating Tumor DNA: Correlation with Response to Checkpoint Inhibitor-Based Immunotherapy.
Yulian Khagi, Aaron M Goodman, +5 authors, Razelle Kurzrock.
Clin Cancer Res, 2017 Oct 04; 23(19). PMID: 28972084    Free PMC article.
Highly Cited.
Radiomics: the bridge between medical imaging and personalized medicine.
Philippe Lambin, Ralph T H Leijenaar, +17 authors, Sean Walsh.
Nat Rev Clin Oncol, 2017 Oct 05; 14(12). PMID: 28975929
Highly Cited. Review.
Improving radiotherapy in cancer treatment: Promises and challenges.
Helen H W Chen, Macus Tien Kuo.
Oncotarget, 2017 Oct 06; 8(37). PMID: 28977985    Free PMC article.
Towards a better cancer precision medicine: systems biology meets immunotherapy.
Bhavneet Bhinder, Olivier Elemento.
Curr Opin Syst Biol, 2017 Oct 11; 2. PMID: 28989987    Free PMC article.
Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma.
Maria-Carmela Speranza, Carmela Passaro, +18 authors, Sean E Lawler.
Neuro Oncol, 2017 Oct 11; 20(2). PMID: 29016938    Free PMC article.
CD4 and CD8 T lymphocyte interplay in controlling tumor growth.
Dmitrij Ostroumov, Nora Fekete-Drimusz, +2 authors, Norman Woller.
Cell Mol Life Sci, 2017 Oct 17; 75(4). PMID: 29032503    Free PMC article.
Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab.
Nadeem Riaz, Jonathan J Havel, +22 authors, Timothy A Chan.
Cell, 2017 Oct 17; 171(4). PMID: 29033130    Free PMC article.
Highly Cited.
Immune engineering: from systems immunology to engineering immunity.
Ning Jiang.
Curr Opin Biomed Eng, 2017 Oct 19; 1. PMID: 29038795    Free PMC article.
Genomic landscape associated with potential response to anti-CTLA-4 treatment in cancers.
Chan-Young Ock, Jun-Eul Hwang, +12 authors, Ju-Seog Lee.
Nat Commun, 2017 Oct 21; 8(1). PMID: 29051489    Free PMC article.
Synthetic RNA-Based Immunomodulatory Gene Circuits for Cancer Immunotherapy.
Lior Nissim, Ming-Ru Wu, +7 authors, Timothy K Lu.
Cell, 2017 Oct 24; 171(5). PMID: 29056342    Free PMC article.
Combined immunotherapy with anti-PDL-1/PD-1 and anti-CD4 antibodies cures syngeneic disseminated neuroblastoma.
Valentina Rigo, Laura Emionite, +6 authors, Michela Croce.
Sci Rep, 2017 Oct 27; 7(1). PMID: 29070883    Free PMC article.
Genome variation across cancers scales with tissue stiffness - an invasion-mutation mechanism and implications for immune cell infiltration.
Charlotte R Pfeifer, Cory M Alvey, Jerome Irianto, Dennis E Discher.
Curr Opin Syst Biol, 2017 Oct 31; 2. PMID: 29082336    Free PMC article.
Vaccination in the immunotherapy of glioblastoma.
Ziren Kong, Yu Wang, Wenbin Ma.
Hum Vaccin Immunother, 2017 Nov 01; 14(2). PMID: 29087782    Free PMC article.
The anti-PD-1 era - an opportunity to enhance radiotherapy for patients with bladder cancer.
Richard C Walshaw, Jamie Honeychurch, Timothy M Illidge, Ananya Choudhury.
Nat Rev Urol, 2017 Nov 02; 15(4). PMID: 29089607
CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation.
Jiehui Deng, Eric S Wang, +44 authors, Kwok-Kin Wong.
Cancer Discov, 2017 Nov 05; 8(2). PMID: 29101163    Free PMC article.
Highly Cited.
'Hotspots' of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization.
Markus Müller, David Gfeller, George Coukos, Michal Bassani-Sternberg.
Front Immunol, 2017 Nov 07; 8. PMID: 29104575    Free PMC article.
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.
Nicholas McGranahan, Rachel Rosenthal, +9 authors, TRACERx Consortium.
Cell, 2017 Nov 07; 171(6). PMID: 29107330    Free PMC article.
Highly Cited.
New trends in antitumor vaccines in melanoma.
Marcos Vasquez, Shirley Tenesaca, Pedro Berraondo.
Ann Transl Med, 2017 Nov 09; 5(19). PMID: 29114542    Free PMC article.
No patient left behind: The promise of immune priming with epigenetic agents.
Corey A Carter, Bryan T Oronsky, +7 authors, Tony R Reid.
Oncoimmunology, 2017 Nov 11; 6(10). PMID: 29123948    Free PMC article.
A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy.
Marta Łuksza, Nadeem Riaz, +9 authors, Benjamin D Greenbaum.
Nature, 2017 Nov 14; 551(7681). PMID: 29132144    Free PMC article.
Highly Cited.
Intertwining DNA-RNA nanocapsules loaded with tumor neoantigens as synergistic nanovaccines for cancer immunotherapy.
Guizhi Zhu, Lei Mei, +11 authors, Xiaoyuan Chen.
Nat Commun, 2017 Nov 15; 8(1). PMID: 29133898    Free PMC article.
Highly Cited.
Targeted Therapies: Immunologic Effects and Potential Applications Outside of Cancer.
Anna E Kersh, Spencer Ng, +7 authors, Brian P Pollack.
J Clin Pharmacol, 2017 Nov 15; 58(1). PMID: 29136276    Free PMC article.
T cell receptor sequencing of early-stage breast cancer tumors identifies altered clonal structure of the T cell repertoire.
John F Beausang, Amanda J Wheeler, +4 authors, Stephen R Quake.
Proc Natl Acad Sci U S A, 2017 Nov 16; 114(48). PMID: 29138313    Free PMC article.
Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses.
Aránzazu Cruz-Adalia, Guillermo Ramirez-Santiago, +10 authors, Esteban Veiga.
Nat Commun, 2017 Nov 18; 8(1). PMID: 29147022    Free PMC article.
The JAK2V617F and CALR exon 9 mutations are shared immunogenic neoantigens in hematological malignancy.
Morten Orebo Holmström, Hans Carl Hasselbalch, Mads Hald Andersen.
Oncoimmunology, 2017 Nov 18; 6(11). PMID: 29147619    Free PMC article.
Trial watch: Immune checkpoint blockers for cancer therapy.
Claire Vanpouille-Box, Claire Lhuillier, +10 authors, Lorenzo Galluzzi.
Oncoimmunology, 2017 Nov 18; 6(11). PMID: 29147629    Free PMC article.
Highly Cited. Review.
Suppression of FIP200 and autophagy by tumor-derived lactate promotes naïve T cell apoptosis and affects tumor immunity.
Houjun Xia, Wei Wang, +12 authors, Weiping Zou.
Sci Immunol, 2017 Nov 19; 2(17). PMID: 29150439    Free PMC article.
Strategies for Bispecific Single Chain Antibody in Cancer Immunotherapy.
Shu-Juan Zhou, Jia Wei, +3 authors, Bao-Rui Liu.
J Cancer, 2017 Nov 21; 8(18). PMID: 29151956    Free PMC article.
Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells.
Ugo Testa, Germana Castelli, Elvira Pelosi.
Med Sci (Basel), 2017 Nov 22; 5(4). PMID: 29156643    Free PMC article.
Biomarkers for immunotherapy in bladder cancer: a moving target.
David H Aggen, Charles G Drake.
J Immunother Cancer, 2017 Nov 22; 5(1). PMID: 29157296    Free PMC article.
Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity.
Nan Guo Ring, Dietmar Herndler-Brandstetter, +11 authors, Irving L Weissman.
Proc Natl Acad Sci U S A, 2017 Nov 22; 114(49). PMID: 29158380    Free PMC article.
Highly Cited.
mRNAs containing NMD-competent premature termination codons are stabilized and translated under UPF1 depletion.
Won Kyu Kim, SeongJu Yun, +4 authors, Hoguen Kim.
Sci Rep, 2017 Nov 22; 7(1). PMID: 29158530    Free PMC article.
PD-L1 expression and CD8+ tumor-infiltrating lymphocytes are associated with ALK rearrangement and clinicopathological features in inflammatory myofibroblastic tumors.
Yoon Jin Cha, Hyo Sup Shim.
Oncotarget, 2017 Nov 23; 8(52). PMID: 29163763    Free PMC article.
Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma.
Martin Lauss, Marco Donia, +10 authors, Göran Jönsson.
Nat Commun, 2017 Nov 25; 8(1). PMID: 29170503    Free PMC article.
Highly Cited.
Targeting immune checkpoints in breast cancer: an update of early results.
Cinzia Solinas, Andrea Gombos, +3 authors, Laurence Buisseret.
ESMO Open, 2017 Nov 28; 2(5). PMID: 29177095    Free PMC article.
Radiotherapy and CTLA-4 Blockade Shape the TCR Repertoire of Tumor-Infiltrating T Cells.
Nils-Petter Rudqvist, Karsten A Pilones, +7 authors, Sandra Demaria.
Cancer Immunol Res, 2017 Nov 29; 6(2). PMID: 29180535    Free PMC article.
Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth.
Giovanni Germano, Simona Lamba, +23 authors, Alberto Bardelli.
Nature, 2017 Dec 01; 552(7683). PMID: 29186113
Highly Cited.
Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy.
Guizhi Zhu, Geoffrey M Lynn, +22 authors, Xiaoyuan Chen.
Nat Commun, 2017 Dec 06; 8(1). PMID: 29203865    Free PMC article.
Distant intracranial failure in melanoma brain metastases treated with stereotactic radiosurgery in the era of immunotherapy and targeted agents.
Sahaja Acharya, Mustafaa Mahmood, +12 authors, Christopher Abraham.
Adv Radiat Oncol, 2017 Dec 06; 2(4). PMID: 29204524    Free PMC article.
Immunotherapy for Prostate Cancer: Where We Are Headed.
Giuseppe Schepisi, Alberto Farolfi, +9 authors, Ugo De Giorgi.
Int J Mol Sci, 2017 Dec 06; 18(12). PMID: 29206214    Free PMC article.
Future cancer research priorities in the USA: a Lancet Oncology Commission.
Elizabeth M Jaffee, Chi Van Dang, +51 authors, Alfred Yung.
Lancet Oncol, 2017 Dec 07; 18(11). PMID: 29208398    Free PMC article.
Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics.
Abhishek D Garg, Sanket More, +6 authors, Lorenzo Galluzzi.
Oncoimmunology, 2017 Dec 07; 6(12). PMID: 29209573    Free PMC article.
Highly Cited. Review.
Trial watch: DNA-based vaccines for oncological indications.
Stefano Pierini, Renzo Perales-Linares, +5 authors, Lorenzo Galluzzi.
Oncoimmunology, 2017 Dec 07; 6(12). PMID: 29209575    Free PMC article.
Newly Emerging Immune Checkpoints: Promises for Future Cancer Therapy.
Robert J Torphy, Richard D Schulick, Yuwen Zhu.
Int J Mol Sci, 2017 Dec 07; 18(12). PMID: 29211042    Free PMC article.
Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy.
Diego Chowell, Luc G T Morris, +17 authors, Timothy A Chan.
Science, 2017 Dec 09; 359(6375). PMID: 29217585    Free PMC article.
Highly Cited.
Drug development in the era of precision medicine.
Sarah A Dugger, Adam Platt, David B Goldstein.
Nat Rev Drug Discov, 2017 Dec 09; 17(3). PMID: 29217837    Free PMC article.
Highly Cited. Review.
Towards personalized, tumour-specific, therapeutic vaccines for cancer.
Zhuting Hu, Patrick A Ott, Catherine J Wu.
Nat Rev Immunol, 2017 Dec 12; 18(3). PMID: 29226910    Free PMC article.
Highly Cited. Review.
Checkpoint Blockade Toxicity and Immune Homeostasis in the Gastrointestinal Tract.
Michael Dougan.
Front Immunol, 2017 Dec 13; 8. PMID: 29230210    Free PMC article.
Highly Cited. Review.
Molecular Biomarkers of Primary and Acquired Resistance to T-Cell-Mediated Immunotherapy in Cancer: Landscape, Clinical Implications, and Future Directions.
Young Kwang Chae, Michael S Oh, Francis J Giles.
Oncologist, 2017 Dec 16; 23(4). PMID: 29242279    Free PMC article.
High-throughput and Sensitive Immunopeptidomics Platform Reveals Profound Interferonγ-Mediated Remodeling of the Human Leukocyte Antigen (HLA) Ligandome.
Chloe Chong, Fabio Marino, +6 authors, Michal Bassani-Sternberg.
Mol Cell Proteomics, 2017 Dec 16; 17(3). PMID: 29242379    Free PMC article.
Merkel Cell Carcinoma Patients Presenting Without a Primary Lesion Have Elevated Markers of Immunity, Higher Tumor Mutation Burden, and Improved Survival.
Natalie Vandeven, Christopher W Lewis, +10 authors, Paul Nghiem.
Clin Cancer Res, 2017 Dec 17; 24(4). PMID: 29246939    Free PMC article.
Preclinical and clinical development of neoantigen vaccines.
L Li, S P Goedegebuure, W E Gillanders.
Ann Oncol, 2017 Dec 19; 28(suppl_12). PMID: 29253113    Free PMC article.
Informatics for cancer immunotherapy.
J Hammerbacher, A Snyder.
Ann Oncol, 2017 Dec 19; 28(suppl_12). PMID: 29253114    Free PMC article.
Emerging biomarkers for the combination of radiotherapy and immune checkpoint blockers.
Claire Lhuillier, Claire Vanpouille-Box, +2 authors, Sandra Demaria.
Semin Cancer Biol, 2017 Dec 21; 52(Pt 2). PMID: 29258856    Free PMC article.
The Positive Relationship Between γH2AX and PD-L1 Expression in Lung Squamous Cell Carcinoma.
Atsushi Osoegawa, Hitomi Hiraishi, +6 authors, Kenji Sugio.
In Vivo, 2017 Dec 25; 32(1). PMID: 29275316    Free PMC article.
Chemo-Immunotherapy: Role of Indoleamine 2,3-Dioxygenase in Defining Immunogenic Versus Tolerogenic Cell Death in the Tumor Microenvironment.
Theodore S Johnson, Tracy Mcgaha, David H Munn.
Adv Exp Med Biol, 2017 Dec 25; 1036. PMID: 29275467    Free PMC article.
Safety Strategies of Genetically Engineered T Cells in Cancer Immunotherapy.
Yan-Bei Ren, Shang-Jun Sun, Shuang-Yin Han.
Curr Pharm Des, 2017 Dec 29; 24(1). PMID: 29283058    Free PMC article.
Immunological landscape of consensus clusters in colorectal cancer.
Pawel Karpinski, Joanna Rossowska, Maria Malgorzata Sasiadek.
Oncotarget, 2017 Dec 30; 8(62). PMID: 29285252    Free PMC article.
Immune system and melanoma biology: a balance between immunosurveillance and immune escape.
Anna Passarelli, Francesco Mannavola, +2 authors, Francesco Silvestris.
Oncotarget, 2017 Dec 30; 8(62). PMID: 29285320    Free PMC article.
Cancer immunotherapy-targeted glypican-3 or neoantigens.
Yasuhiro Shimizu, Toshihiro Suzuki, +4 authors, Tetsuya Nakatsura.
Cancer Sci, 2017 Dec 30; 109(3). PMID: 29285841    Free PMC article.
Immunopharmacogenomics towards personalized cancer immunotherapy targeting neoantigens.
Kazuma Kiyotani, Hiu Ting Chan, Yusuke Nakamura.
Cancer Sci, 2017 Dec 31; 109(3). PMID: 29288513    Free PMC article.
PD-1 inhibitors in endometrial cancer.
Romualdo Barroso-Sousa, Patrick A Ott.
Oncotarget, 2018 Jan 02; 8(63). PMID: 29290936    Free PMC article.
Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution.
Mirjana Efremova, Dietmar Rieder, +8 authors, Zlatko Trajanoski.
Nat Commun, 2018 Jan 04; 9(1). PMID: 29296022    Free PMC article.
Highly Cited.
A library-based screening method identifies neoantigen-reactive T cells in peripheral blood prior to relapse of ovarian cancer.
Spencer D Martin, Darin A Wick, +3 authors, Brad H Nelson.
Oncoimmunology, 2018 Jan 04; 7(1). PMID: 29296522    Free PMC article.
Mutation load and an effector T-cell gene signature may distinguish immunologically distinct and clinically relevant lymphoma subsets.
Christopher R Bolen, Ronald McCord, +10 authors, Jeffrey M Venstrom.
Blood Adv, 2018 Jan 04; 1(22). PMID: 29296835    Free PMC article.
Regulation of PD-1/PD-L1 pathway and resistance to PD-1/PD-L1 blockade.
Jie Bai, Zhitao Gao, +3 authors, Jing Nie.
Oncotarget, 2018 Jan 05; 8(66). PMID: 29299180    Free PMC article.
Family A and B DNA Polymerases in Cancer: Opportunities for Therapeutic Interventions.
Vinit Shanbhag, Shrikesh Sachdev, +2 authors, Kamalendra Singh.
Biology (Basel), 2018 Jan 06; 7(1). PMID: 29301327    Free PMC article.
Immunotherapy for Non-small-cell Lung Cancer: Current Status and Future Obstacles.
Ju Hwan Cho.
Immune Netw, 2018 Jan 06; 17(6). PMID: 29302251    Free PMC article.
The T cell repertoire in tumors overlaps with pulmonary inflammatory lesions in patients treated with checkpoint inhibitors.
Heinz Läubli, Viktor H Koelzer, +6 authors, Alfred Zippelius.
Oncoimmunology, 2018 Jan 09; 7(2). PMID: 29308309    Free PMC article.
Hitting the Target: How T Cells Detect and Eliminate Tumors.
Anthony E Zamora, Jeremy Chase Crawford, Paul G Thomas.
J Immunol, 2018 Jan 10; 200(2). PMID: 29311380    Free PMC article.
Innate immunity mediated by dendritic cells/macrophages plays a central role in the early period in tumor treatment using gene of Mycobacterium tuberculosis antigen.
Takahiro Ushigusa, Yoshiyuki Koyama, +8 authors, Kikuya Sugiura.
J Vet Med Sci, 2018 Jan 10; 80(2). PMID: 29311492    Free PMC article.
Toll-Like Receptor 3 Signal in Dendritic Cells Benefits Cancer Immunotherapy.
Misako Matsumoto, Yohei Takeda, Megumi Tatematsu, Tsukasa Seya.
Front Immunol, 2018 Jan 10; 8. PMID: 29312355    Free PMC article.
The Role of Mass Spectrometry and Proteogenomics in the Advancement of HLA Epitope Prediction.
Amanda L Creech, Ying S Ting, +5 authors, Jennifer G Abelin.
Proteomics, 2018 Jan 10; 18(12). PMID: 29314742    Free PMC article.
Mechanisms of resistance to immune checkpoint inhibitors.
Russell W Jenkins, David A Barbie, Keith T Flaherty.
Br J Cancer, 2018 Jan 11; 118(1). PMID: 29319049    Free PMC article.
Highly Cited. Review.
Precision oncology in the age of integrative genomics.
Chandan Kumar-Sinha, Arul M Chinnaiyan.
Nat Biotechnol, 2018 Jan 11; 36(1). PMID: 29319699    Free PMC article.
Cell Membrane Bioconjugation and Membrane-Derived Nanomaterials for Immunotherapy.
Peter Y Li, Zhiyuan Fan, Hao Cheng.
Bioconjug Chem, 2018 Jan 13; 29(3). PMID: 29323870    Free PMC article.
Co-delivery of tumor antigen and dual toll-like receptor ligands into dendritic cell by silicon microparticle enables efficient immunotherapy against melanoma.
Motao Zhu, Xilai Ding, +6 authors, Rong-Fu Wang.
J Control Release, 2018 Jan 13; 272. PMID: 29325699    Free PMC article.
Anti-Programmed Cell Death 1/Ligand 1 (PD-1/PD-L1) Antibodies for the Treatment of Urothelial Carcinoma: State of the Art and Future Development.
Thomas Powles, Andrea Necchi, +2 authors, Andrea B Apolo.
Clin Genitourin Cancer, 2018 Jan 13; 16(2). PMID: 29325739    Free PMC article.
Cancer immunotherapy beyond immune checkpoint inhibitors.
Julian A Marin-Acevedo, Aixa E Soyano, +2 authors, Yanyan Lou.
J Hematol Oncol, 2018 Jan 14; 11(1). PMID: 29329556    Free PMC article.
Highly Cited. Review.
Dinaciclib induces immunogenic cell death and enhances anti-PD1-mediated tumor suppression.
Dewan Md Sakib Hossain, Sarah Javaid, +8 authors, Alissa Chackerian.
J Clin Invest, 2018 Jan 18; 128(2). PMID: 29337311    Free PMC article.
Tumor Immunity and Survival as a Function of Alternative Neopeptides in Human Cancer.
Andrew J Rech, David Balli, +4 authors, Robert H Vonderheide.
Cancer Immunol Res, 2018 Jan 18; 6(3). PMID: 29339376    Free PMC article.
DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer.
Na Luo, Mellissa J Nixon, +10 authors, Justin M Balko.
Nat Commun, 2018 Jan 18; 9(1). PMID: 29339738    Free PMC article.
Highly Cited.
Immunotherapy of patient with hepatocellular carcinoma using cytotoxic T lymphocytes ex vivo activated with tumor antigen-pulsed dendritic cells.
Ying Wang, Xijing Yang, +11 authors, Qijun Qian.
J Cancer, 2018 Jan 19; 9(2). PMID: 29344274    Free PMC article.
Present status and future perspective of peptide-based vaccine therapy for urological cancer.
Wataru Obara, Mitsugu Kanehira, +3 authors, Ryo Takata.
Cancer Sci, 2018 Jan 19; 109(3). PMID: 29345737    Free PMC article.
Chemotherapy weakly contributes to predicted neoantigen expression in ovarian cancer.
Timothy O'Donnell, Elizabeth L Christie, +5 authors, Jeff Hammerbacher.
BMC Cancer, 2018 Jan 24; 18(1). PMID: 29357823    Free PMC article.
Unwrapping the genomic characteristics of urothelial bladder cancer and successes with immune checkpoint blockade therapy.
Wen Cheng, Dian Fu, Feng Xu, Zhengyu Zhang.
Oncogenesis, 2018 Jan 24; 7(1). PMID: 29358573    Free PMC article.
Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma.
Joshua R Veatch, Sylvia M Lee, +10 authors, Stanley R Riddell.
J Clin Invest, 2018 Jan 24; 128(4). PMID: 29360643    Free PMC article.
Highly Cited.
Mechanisms of Resistance to PD-1 and PD-L1 Blockade.
Theodore S Nowicki, Siwen Hu-Lieskovan, Antoni Ribas.
Cancer J, 2018 Jan 24; 24(1). PMID: 29360728    Free PMC article.
Highly Cited. Review.
Xenogeneic cell therapy provides a novel potential therapeutic option for cancers by restoring tissue function, repairing cancer wound and reviving anti-tumor immune responses.
Chi-Ping Huang, Chi-Cheng Chen, Chih-Rong Shyr.
Cancer Cell Int, 2018 Jan 27; 18. PMID: 29371832    Free PMC article.
Role of immune-checkpoint inhibitors in lung cancer.
Prantesh Jain, Chhavi Jain, Vamsidhar Velcheti.
Ther Adv Respir Dis, 2018 Feb 02; 12. PMID: 29385894    Free PMC article.
Colorectal cancer prevention: Immune modulation taking the stage.
Rochelle Fletcher, Yi-Jun Wang, +3 authors, Lin Zhang.
Biochim Biophys Acta Rev Cancer, 2018 Feb 03; 1869(2). PMID: 29391185    Free PMC article.
Recent Advances in Targeting CD8 T-Cell Immunity for More Effective Cancer Immunotherapy.
Aurélie Durgeau, Yasemin Virk, Stéphanie Corgnac, Fathia Mami-Chouaib.
Front Immunol, 2018 Feb 07; 9. PMID: 29403496    Free PMC article.
Highly Cited. Review.
Polymeric microneedles for transdermal protein delivery.
Yanqi Ye, Jicheng Yu, +2 authors, Zhen Gu.
Adv Drug Deliv Rev, 2018 Feb 07; 127. PMID: 29408182    Free PMC article.
Cancer immunogenomic approach to neoantigen discovery in a checkpoint blockade responsive murine model of oral cavity squamous cell carcinoma.
Paul Zolkind, Dariusz Przybylski, +11 authors, Ravindra Uppaluri.
Oncotarget, 2018 Feb 10; 9(3). PMID: 29423108    Free PMC article.
The New Age of -omics in Urothelial Cancer - Re-wording Its Diagnosis and Treatment.
Theodora Katsila, Michalis Liontos, +2 authors, Dimitrios Kardamakis.
EBioMedicine, 2018 Feb 13; 28. PMID: 29428524    Free PMC article.
Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy.
Xin Hong, Ryan J Sullivan, +20 authors, Daniel A Haber.
Proc Natl Acad Sci U S A, 2018 Feb 18; 115(10). PMID: 29453278    Free PMC article.
Highly Cited.
Next Generation Immunotherapy for Pancreatic Cancer: DNA Vaccination is Seeking New Combo Partners.
Paola Cappello, Claudia Curcio, +3 authors, Francesco Novelli.
Cancers (Basel), 2018 Feb 22; 10(2). PMID: 29462900    Free PMC article.
Prognostic impact of CD4-positive T cell subsets in early breast cancer: a study based on the FinHer trial patient population.
Marcus Schmidt, Veronika Weyer-Elberich, +12 authors, Heikki Joensuu.
Breast Cancer Res, 2018 Feb 28; 20(1). PMID: 29482642    Free PMC article.
Importance of immune monitoring approaches and the use of immune checkpoints for the treatment of diffuse intrinsic pontine glioma: From bench to clinic and vice versa (Review).
Jorge Augusto Borin Scutti.
Int J Oncol, 2018 Feb 28; 52(4). PMID: 29484440    Free PMC article.
A facile approach to enhance antigen response for personalized cancer vaccination.
Aileen Weiwei Li, Miguel C Sobral, +10 authors, David J Mooney.
Nat Mater, 2018 Mar 07; 17(6). PMID: 29507416    Free PMC article.
Highly Cited.
Randomized phase II trial of autologous dendritic cell vaccines versus autologous tumor cell vaccines in metastatic melanoma: 5-year follow up and additional analyses.
Robert O Dillman, Andrew N Cornforth, +3 authors, Carol Depriest.
J Immunother Cancer, 2018 Mar 08; 6(1). PMID: 29510745    Free PMC article.
Genetic Mechanisms of Immune Evasion in Colorectal Cancer.
Catherine S Grasso, Marios Giannakis, +49 authors, Ulrike Peters.
Cancer Discov, 2018 Mar 08; 8(6). PMID: 29510987    Free PMC article.
Highly Cited.
Adoptive cancer immunotherapy using DNA-demethylated T helper cells as antigen-presenting cells.
Alexei F Kirkin, Karine N Dzhandzhugazyan, +14 authors, Walter Fischer.
Nat Commun, 2018 Mar 08; 9(1). PMID: 29511178    Free PMC article.
Development of Molecularly Targeted Agents and Immunotherapies in Glioblastoma: A Personalized Approach.
Niamh Coleman, Malaka Ameratunga, Juanita Lopez.
Clin Med Insights Oncol, 2018 Mar 08; 12. PMID: 29511362    Free PMC article.
The Expression and Prognostic Impact of Immune Cytolytic Activity-Related Markers in Human Malignancies: A Comprehensive Meta-analysis.
Constantinos Roufas, Dimitrios Chasiotis, +3 authors, Apostolos Zaravinos.
Front Oncol, 2018 Mar 09; 8. PMID: 29515971    Free PMC article.
Genotypic and phenotypic signatures to predict immune checkpoint blockade therapy response in patients with colorectal cancer.
Xianda Zhao, Audre May, Emil Lou, Subbaya Subramanian.
Transl Res, 2018 Mar 09; 196. PMID: 29518351    Free PMC article.
Adjuvant immunotherapy for cancer: both dendritic cell-priming and check-point inhibitor blockade are required for immunotherapy.
Tsukasa Seya, Yohei Takeda, +3 authors, Misako Matsumoto.
Proc Jpn Acad Ser B Phys Biol Sci, 2018 Mar 13; 94(3). PMID: 29526974    Free PMC article.
Next-generation molecular therapy in lung cancer.
Jun Qian, Pierre P Massion.
Transl Lung Cancer Res, 2018 Mar 14; 7(Suppl 1). PMID: 29531901    Free PMC article.
Sensitive and frequent identification of high avidity neo-epitope specific CD8 + T cells in immunotherapy-naive ovarian cancer.
Sara Bobisse, Raphael Genolet, +21 authors, Alexandre Harari.
Nat Commun, 2018 Mar 17; 9(1). PMID: 29545564    Free PMC article.
Highly Cited.
Current status and perspectives in immunotherapy for metastatic melanoma.
Riccardo Marconcini, Francesco Spagnolo, +13 authors, Italian Melanoma Intergroup (IMI).
Oncotarget, 2018 Mar 20; 9(15). PMID: 29552325    Free PMC article.
Cancer vaccines: translation from mice to human clinical trials.
Hoyoung Maeng, Masaki Terabe, Jay A Berzofsky.
Curr Opin Immunol, 2018 Mar 20; 51. PMID: 29554495    Free PMC article.
Combining Immunotherapy and Radiotherapy for Cancer Treatment: Current Challenges and Future Directions.
Yifan Wang, Weiye Deng, +4 authors, Steven H Lin.
Front Pharmacol, 2018 Mar 21; 9. PMID: 29556198    Free PMC article.
Highly Cited. Review.
Recent advances in medical therapy for metastatic urothelial cancer.
Takeshi Yuasa, Shinji Urakami, Junji Yonese.
Int J Clin Oncol, 2018 Mar 21; 23(4). PMID: 29556919    Free PMC article.
Immunotherapy in pancreatic adenocarcinoma-overcoming barriers to response.
Ari Rosenberg, Devalingam Mahalingam.
J Gastrointest Oncol, 2018 Mar 23; 9(1). PMID: 29564181    Free PMC article.
Systemic administration of a TLR7 agonist attenuates regulatory T cells by dendritic cell modification and overcomes resistance to PD-L1 blockade therapy.
Naoto Nishii, Hidetake Tachinami, +8 authors, Miyuki Azuma.
Oncotarget, 2018 Mar 24; 9(17). PMID: 29568358    Free PMC article.
Anti-CTLA-4 therapy requires an Fc domain for efficacy.
Jessica R Ingram, Olga S Blomberg, +15 authors, Michael Dougan.
Proc Natl Acad Sci U S A, 2018 Mar 28; 115(15). PMID: 29581255    Free PMC article.
Highly Cited.
Tumor immunity landscape in non-small cell lung cancer.
Xiaoqing Yu, Xuefeng Wang.
PeerJ, 2018 Mar 30; 6. PMID: 29593943    Free PMC article.
Vaccine Strategies in Gliomas.
Michael Platten, Lukas Bunse, +3 authors, Wolfgang Wick.
Curr Treat Options Neurol, 2018 Mar 30; 20(5). PMID: 29594595
A Targeted LC-MS Strategy for Low-Abundant HLA Class-I-Presented Peptide Detection Identifies Novel Human Papillomavirus T-Cell Epitopes.
Renata Blatnik, Nitya Mohan, +10 authors, Angelika B Riemer.
Proteomics, 2018 Apr 01; 18(11). PMID: 29603667    Free PMC article.
Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers.
Daniel J McGrail, Lorenzo Federico, +6 authors, Nidhi Sahni.
Nat Commun, 2018 Apr 05; 9(1). PMID: 29615613    Free PMC article.
Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody.
Randi B Gombos, Ana Gonzalez, +24 authors, Nicholas S Wilson.
PLoS One, 2018 Apr 05; 13(4). PMID: 29617360    Free PMC article.
Immunotherapy of melanoma.
Iwona Lugowska, Pawel Teterycz, Piotr Rutkowski.
Contemp Oncol (Pozn), 2018 Apr 10; 22(1A). PMID: 29628796    Free PMC article.
Oncolytic Viruses as Antigen-Agnostic Cancer Vaccines.
Stephen J Russell, Glen N Barber.
Cancer Cell, 2018 Apr 11; 33(4). PMID: 29634947    Free PMC article.
Highly Cited. Review.
Circulating biomarkers for early diagnosis of pancreatic cancer: facts and hopes.
Xu Zhang, Si Shi, +3 authors, Jin Xu.
Am J Cancer Res, 2018 Apr 11; 8(3). PMID: 29636993    Free PMC article.
Peptide Vaccine Formulation Controls the Duration of Antigen Presentation and Magnitude of Tumor-Specific CD8+ T Cell Response.
Hiep Khong, Annika Volmari, +10 authors, Willem W Overwijk.
J Immunol, 2018 Apr 13; 200(10). PMID: 29643190    Free PMC article.
Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.
Matthew D Hellmann, Tavi Nathanson, +29 authors, Jedd D Wolchok.
Cancer Cell, 2018 Apr 17; 33(5). PMID: 29657128    Free PMC article.
Highly Cited.
Strategy to targeting the immune resistance and novel therapy in colorectal cancer.
Wang Gang, Jun-Jie Wang, +6 authors, Xing-Li Fu.
Cancer Med, 2018 Apr 17; 7(5). PMID: 29658188    Free PMC article.
Combination of immunotherapy with chemotherapy and radiotherapy in lung cancer: is this the beginning of the end for cancer?
Chiara Lazzari, Niki Karachaliou, +7 authors, Vanesa Gregorc.
Ther Adv Med Oncol, 2018 Apr 18; 10. PMID: 29662546    Free PMC article.
Highly Cited. Review.
PD-L1 expression testing in non-small cell lung cancer.
Cristina Teixidó, Noelia Vilariño, Roxana Reyes, Noemí Reguart.
Ther Adv Med Oncol, 2018 Apr 18; 10. PMID: 29662547    Free PMC article.
Highly Cited. Review.
A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors.
Tingting Wang, Dangge Wang, +6 authors, Yaping Li.
Nat Commun, 2018 Apr 20; 9(1). PMID: 29670088    Free PMC article.
Elimination of established tumors with nanodisc-based combination chemoimmunotherapy.
Rui Kuai, Wenmin Yuan, +5 authors, James J Moon.
Sci Adv, 2018 Apr 21; 4(4). PMID: 29675465    Free PMC article.
Highly Cited.
Utilizing the nanosecond pulse technique to improve antigen intracellular delivery and presentation to treat tongue squamous cell carcinoma.
C Gao, X Zhang, +4 authors, J Wang.
Med Oral Patol Oral Cir Bucal, 2018 Apr 24; 23(3). PMID: 29680844    Free PMC article.
Gender and outcomes in non-small cell lung cancer: an old prognostic variable comes back for targeted therapy and immunotherapy?
Joseph A Pinto, Carlos S Vallejos, +10 authors, Christian Rolfo.
ESMO Open, 2018 Apr 24; 3(3). PMID: 29682332    Free PMC article.
Neutral Theory and the Somatic Evolution of Cancer.
Vincent L Cannataro, Jeffrey P Townsend.
Mol Biol Evol, 2018 Apr 24; 35(6). PMID: 29684198    Free PMC article.
Checkpoint Inhibitors in the Treatment of Breast Cancer.
Tomas G Lyons, Maura N Dickler, Elizabeth E Comen.
Curr Oncol Rep, 2018 May 02; 20(7). PMID: 29713831
Prediction of tumor mutation burden in breast cancer based on the expression of ER, PR, HER-2, and Ki-67.
Junnan Xu, Xiangyu Guo, Mingxi Jing, Tao Sun.
Onco Targets Ther, 2018 May 03; 11. PMID: 29719409    Free PMC article.
Complimentary mechanisms of dual checkpoint blockade expand unique T-cell repertoires and activate adaptive anti-tumor immunity in triple-negative breast tumors.
Erika J Crosby, Junping Wei, +10 authors, Zachary C Hartman.
Oncoimmunology, 2018 May 04; 7(5). PMID: 29721371    Free PMC article.
Chemical Control over T-Cell Activation in Vivo Using Deprotection of trans-Cyclooctene-Modified Epitopes.
Anouk M F van der Gracht, Mark A R de Geus, +12 authors, Sander I van Kasteren.
ACS Chem Biol, 2018 May 08; 13(6). PMID: 29733186    Free PMC article.
Recent Advances in Prostate Cancer Treatment and Drug Discovery.
Ekaterina Nevedomskaya, Simon J Baumgart, Bernard Haendler.
Int J Mol Sci, 2018 May 08; 19(5). PMID: 29734647    Free PMC article.
Highly Cited. Review.
Targeting Head and Neck Cancer by Vaccination.
Chuan Wang, James Dickie, +3 authors, Natalia Savelyeva.
Front Immunol, 2018 May 10; 9. PMID: 29740440    Free PMC article.
A robust response to combination immune checkpoint inhibitor therapy in HPV-related small cell cancer: a case report.
Won Jin Ho, Lisa Rooper, Sarah Sagorsky, Hyunseok Kang.
J Immunother Cancer, 2018 May 11; 6(1). PMID: 29743117    Free PMC article.
Immune checkpoint inhibitors in gastrointestinal malignancies.
Vishal Jindal.
J Gastrointest Oncol, 2018 May 15; 9(2). PMID: 29755779    Free PMC article.
Durable complete responses in some recurrent high-grade glioma patients treated with Toca 511 + Toca FC.
Timothy F Cloughesy, Joseph Landolfi, +23 authors, Tobias Walbert.
Neuro Oncol, 2018 May 16; 20(10). PMID: 29762717    Free PMC article.
Nature of tumour rejection antigens in ovarian cancer.
Muzamil Y Want, Amit A Lugade, Sebastiano Battaglia, Kunle Odunsi.
Immunology, 2018 May 18; 155(2). PMID: 29772069    Free PMC article.
Immunosurveillance of cancer and the heat shock protein-CD91 pathway.
Robert J Binder.
Cell Immunol, 2018 May 23; 343. PMID: 29784128    Free PMC article.
Links between Immunologic Memory and Metabolic Cycling.
Matthew A Cottam, Hana A Itani, Arch A Beasley, Alyssa H Hasty.
J Immunol, 2018 May 23; 200(11). PMID: 29784764    Free PMC article.
The era of immunogenomics/immunopharmacogenomics.
Makda Zewde, Kazuma Kiyotani, +13 authors, Yusuke Nakamura.
J Hum Genet, 2018 May 23; 63(8). PMID: 29785006
RTK-RAS pathway mutation is enriched in myeloid sarcoma.
Mihong Choi, Yoon Kyung Jeon, +6 authors, Youngil Koh.
Blood Cancer J, 2018 May 24; 8(5). PMID: 29789584    Free PMC article.
Vaccine immunotherapy with ARNAX induces tumor-specific memory T cells and durable anti-tumor immunity in mouse models.
Yohei Takeda, Sumito Yoshida, +4 authors, Misako Matsumoto.
Cancer Sci, 2018 May 24; 109(7). PMID: 29791768    Free PMC article.
Whole-genome sequencing reveals genomic signatures associated with the inflammatory microenvironments in Chinese NSCLC patients.
Cheng Wang, Rong Yin, +23 authors, Hongbing Shen.
Nat Commun, 2018 May 26; 9(1). PMID: 29799009    Free PMC article.
Indoleamine 2,3-dioxygenase 1 and overall survival of patients diagnosed with esophageal cancer.
Ari J Rosenberg, Derek A Wainwright, +12 authors, Victoria M Villaflor.
Oncotarget, 2018 May 29; 9(34). PMID: 29805749    Free PMC article.
Human T-cell lymphotropic/leukemia virus type 1 (HTLV-1) Tax-specific T-cell exhaustion in HTLV-1-infected individuals.
Ayako Masaki, Takashi Ishida, +9 authors, Shinsuke Iida.
Cancer Sci, 2018 May 31; 109(8). PMID: 29845702    Free PMC article.
Diagnosis and Management of Hepatitis in Patients on Checkpoint Blockade.
Kerry Reynolds, Molly Thomas, Michael Dougan.
Oncologist, 2018 Jun 02; 23(9). PMID: 29853659    Free PMC article.
Immune therapies in pancreatic ductal adenocarcinoma: Where are we now?
Marc Hilmi, Laurent Bartholin, Cindy Neuzillet.
World J Gastroenterol, 2018 Jun 02; 24(20). PMID: 29853732    Free PMC article.
Highly Cited. Review.
Negative selection in tumor genome evolution acts on essential cellular functions and the immunopeptidome.
Luis Zapata, Oriol Pich, +3 authors, Martin H Schaefer.
Genome Biol, 2018 Jun 02; 19(1). PMID: 29855388    Free PMC article.
Clinical significance of circulating tumor cells in blood from patients with gastric cancer.
Takaaki Arigami, Yoshikazu Uenosono, +7 authors, Shoji Natsugoe.
Ann Gastroenterol Surg, 2017 Apr 25; 1(1). PMID: 29863113    Free PMC article.
Transcriptional characterization of immunological infiltrates and their relation with glioblastoma patients overall survival.
Mariana Brutschin Pereira, Luciana Rodrigues Carvalho Barros, +4 authors, Guido Lenz.
Oncoimmunology, 2018 Jun 07; 7(6). PMID: 29872555    Free PMC article.
Cancer immunotherapy: broadening the scope of targetable tumours.
Jitske van den Bulk, Els Me Verdegaal, Noel Fcc de Miranda.
Open Biol, 2018 Jun 08; 8(6). PMID: 29875199    Free PMC article.
Current status of cancer immunotherapy for esophageal squamous cell carcinoma.
Koji Kono, Kousaku Mimura, +9 authors, Shinji Ohki.
Esophagus, 2018 Jun 13; 15(1). PMID: 29892809
Pathogenesis of Skin Carcinomas and a Stem Cell as Focal Origin.
Frank R de Gruijl, Cornelis P Tensen.
Front Med (Lausanne), 2018 Jun 14; 5. PMID: 29896477    Free PMC article.
Vaccination-induced skin-resident memory CD8+ T cells mediate strong protection against cutaneous melanoma.
Felipe Gálvez-Cancino, Ernesto López, +11 authors, Alvaro Lladser.
Oncoimmunology, 2018 Jun 15; 7(7). PMID: 29900048    Free PMC article.
Ilixadencel - an Allogeneic Cell-Based Anticancer Immune Primer for Intratumoral Administration.
Alex Karlsson-Parra, Juliana Kovacka, +4 authors, Peter Suenaert.
Pharm Res, 2018 Jun 16; 35(8). PMID: 29904904    Free PMC article.
Tumor Regression and Cure Depends on Sustained Th1 Responses.
Min Dai, Ingegerd Hellstrom, +2 authors, Karl Erik Hellstrom.
J Immunother, 2018 Jun 19; 41(8). PMID: 29912725    Free PMC article.
T cell receptor repertoire profiling predicts the prognosis of HBV-associated hepatocellular carcinoma.
Kai-Rong Lin, Fei-Wen Deng, +6 authors, Wei Luo.
Cancer Med, 2018 Jun 28; 7(8). PMID: 29947152    Free PMC article.
PD-1/PD-L1 pathway blockade works as an effective and practical therapy for cancer immunotherapy.
Long Jia, Qi Zhang, Rongxin Zhang.
Cancer Biol Med, 2018 Jun 29; 15(2). PMID: 29951336    Free PMC article.
Macrophage targeting: opening new possibilities for cancer immunotherapy.
Luca Cassetta, Takanori Kitamura.
Immunology, 2018 Jul 03; 155(3). PMID: 29963704    Free PMC article.
Comparative Secretome Profiling and Mutant Protein Identification in Metastatic Prostate Cancer Cells by Quantitative Mass Spectrometry-based Proteomics.
Oh Kwang Kwon, Ju Mi Jeon, +3 authors, Sangkyu Lee.
Cancer Genomics Proteomics, 2018 Jul 07; 15(4). PMID: 29976633    Free PMC article.
Tumor Dendritic Cells (DCs) Derived from Precursors of Conventional DCs Are Dispensable for Intratumor CTL Responses.
Jun Diao, Hongtao Gu, +2 authors, Mark S Cattral.
J Immunol, 2018 Jul 13; 201(4). PMID: 29997124    Free PMC article.
Immune reprogramming via PD-1 inhibition enhances early-stage lung cancer survival.
Geoffrey J Markowitz, Lauren S Havel, +10 authors, Vivek Mittal.
JCI Insight, 2018 Jul 13; 3(13). PMID: 29997286    Free PMC article.
Dendritic Cells in the Cross Hair for the Generation of Tailored Vaccines.
Laura Gornati, Ivan Zanoni, Francesca Granucci.
Front Immunol, 2018 Jul 13; 9. PMID: 29997628    Free PMC article.
Nivolumab use for BRCA gene mutation carriers with recurrent epithelial ovarian cancer: A case series.
Koji Matsuo, Samantha E Spragg, +4 authors, Lynda D Roman.
Gynecol Oncol Rep, 2018 Jul 13; 25. PMID: 29998185    Free PMC article.
Microbial biomarkers for immune checkpoint blockade therapy against cancer.
Keishi Adachi, Koji Tamada.
J Gastroenterol, 2018 Jul 14; 53(9). PMID: 30003334    Free PMC article.
Natural T-cell ligands that are created by genetic variants can be transferred between cells by extracellular vesicles.
Anita N Kremer, Marijke I Zonneveld, +5 authors, Marieke Griffioen.
Eur J Immunol, 2018 Jul 17; 48(10). PMID: 30011060    Free PMC article.
Neoantigen Vaccine Delivery for Personalized Anticancer Immunotherapy.
Yugang Guo, Kewen Lei, Li Tang.
Front Immunol, 2018 Jul 18; 9. PMID: 30013560    Free PMC article.
Highly Cited. Review.
Improved Induction of Anti-Melanoma T Cells by Adenovirus-5/3 Fiber Modification to Target Human DCs.
Dafni Chondronasiou, Tracy-Jane T H D Eisden, +7 authors, Rieneke van de Ven.
Vaccines (Basel), 2018 Jul 20; 6(3). PMID: 30022005    Free PMC article.
Novel frontiers in detecting cancer metastasis.
Stanley P Leong, Carmen Ballesteros-Merino, +4 authors, Mojca Skoberne.
Clin Exp Metastasis, 2018 Jul 20; 35(5-6). PMID: 30022365
CD11c+ MHCIIlo GM-CSF-bone marrow-derived dendritic cells act as antigen donor cells and as antigen presenting cells in neoepitope-elicited tumor immunity against a mouse fibrosarcoma.
Hakimeh Ebrahimi-Nik, William L Corwin, +3 authors, Pramod K Srivastava.
Cancer Immunol Immunother, 2018 Jul 22; 67(9). PMID: 30030558    Free PMC article.
A novel allogeneic off-the-shelf dendritic cell vaccine for post-remission treatment of elderly patients with acute myeloid leukemia.
Arjan A van de Loosdrecht, Sandra van Wetering, +8 authors, Tanja D de Gruijl.
Cancer Immunol Immunother, 2018 Jul 25; 67(10). PMID: 30039426    Free PMC article.
Interferon gene therapy reprograms the leukemia microenvironment inducing protective immunity to multiple tumor antigens.
Giulia Escobar, Luigi Barbarossa, +12 authors, Luigi Naldini.
Nat Commun, 2018 Jul 26; 9(1). PMID: 30042420    Free PMC article.
Editorial: Local Immunotherapy: A Way to Convert Tumors From "Cold" to "Hot".
Marijo Bilusic, James L Gulley.
J Natl Cancer Inst, 2018 Jul 28; 109(12). PMID: 30053078    Free PMC article.
Immunotherapy for esophageal squamous cell carcinoma: a review.
Kosaku Mimura, Leo Yamada, +9 authors, Koji Kono.
Fukushima J Med Sci, 2018 Jul 31; 64(2). PMID: 30058598    Free PMC article.
Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma.
Bracha Shraibman, Eilon Barnea, +34 authors, Arie Admon.
Mol Cell Proteomics, 2018 Aug 04; 17(11). PMID: 30072578    Free PMC article.
Current Strategies and Applications for Precision Drug Design.
Chen Wang, Pan Xu, +3 authors, Cheng Luo.
Front Pharmacol, 2018 Aug 04; 9. PMID: 30072901    Free PMC article.
Poly(propylacrylic acid)-peptide nanoplexes as a platform for enhancing the immunogenicity of neoantigen cancer vaccines.
Feng Qiu, Kyle W Becker, +6 authors, John T Wilson.
Biomaterials, 2018 Aug 15; 182. PMID: 30107272    Free PMC article.
A cancer vaccine approach for personalized treatment of Lynch Syndrome.
Snigdha Majumder, Rakshit Shah, +13 authors, Arati Khanna-Gupta.
Sci Rep, 2018 Aug 16; 8(1). PMID: 30108227    Free PMC article.
Plants Used by Bapedi Traditional Healers to Treat Asthma and Related Symptoms in Limpopo Province, South Africa.
Sebua Silas Semenya, Alfred Maroyi.
Evid Based Complement Alternat Med, 2018 Aug 16; 2018. PMID: 30108649    Free PMC article.
Intratumoral immune-biomarkers and mismatch repair status in leiyomyosarcoma -potential predictive markers for adjuvant treatment: a pilot study.
Jonathan E Cohen, Feras Eleyan, +2 authors, Daniela Katz.
Oncotarget, 2018 Aug 17; 9(56). PMID: 30112112    Free PMC article.
Identification of non-mutated neoantigens presented by TAP-deficient tumors.
Koen A Marijt, Laura Blijleven, +7 authors, Thorbald van Hall.
J Exp Med, 2018 Aug 18; 215(9). PMID: 30115740    Free PMC article.
PEGylated tumor cell membrane vesicles as a new vaccine platform for cancer immunotherapy.
Lukasz J Ochyl, Joseph D Bazzill, +3 authors, James J Moon.
Biomaterials, 2018 Aug 20; 182. PMID: 30121425    Free PMC article.
Current landscape and future directions of biomarkers for predicting responses to immune checkpoint inhibitors.
Yingming Zhu, Fen Zhao, Zhenxiang Li, Jinming Yu.
Cancer Manag Res, 2018 Aug 21; 10. PMID: 30122997    Free PMC article.
Aptamer-based targeted therapy.
Guizhi Zhu, Xiaoyuan Chen.
Adv Drug Deliv Rev, 2018 Aug 21; 134. PMID: 30125604    Free PMC article.
Personalized cancer neoantigen vaccines come of age.
Yanhong Chu, Qin Liu, Jia Wei, Baorui Liu.
Theranostics, 2018 Aug 22; 8(15). PMID: 30128050    Free PMC article.
Immunological-based approaches for cancer therapy.
Luciana Barros, Marco Antonio Pretti, +3 authors, Martin Hernán Bonamino.
Clinics (Sao Paulo), 2018 Aug 23; 73(suppl 1). PMID: 30133560    Free PMC article.
Future prospects of immune checkpoint blockade in cancer: from response prediction to overcoming resistance.
Young-Jun Park, Da-Sol Kuen, Yeonseok Chung.
Exp Mol Med, 2018 Aug 24; 50(8). PMID: 30135516    Free PMC article.
Highly Cited. Review.
Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma.
Christof C Smith, Kathryn E Beckermann, +15 authors, Benjamin G Vincent.
J Clin Invest, 2018 Aug 24; 128(11). PMID: 30137025    Free PMC article.
Highly Cited.
Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes.
Lien Van Hoecke, Sandra Van Lint, +6 authors, Xavier Saelens.
Nat Commun, 2018 Aug 26; 9(1). PMID: 30143632    Free PMC article.
Vaccination with induced pluripotent stem cells confers protection against cancer.
Kavitha Yaddanapudi, Chi Li, John W Eaton.
Stem Cell Investig, 2018 Aug 28; 5. PMID: 30148156    Free PMC article.
Pretreatment hematological markers predict clinical outcome in cancer patients receiving immune checkpoint inhibitors: A meta-analysis.
Qiaoyun Tan, Shuxia Liu, +2 authors, Yuankai Shi.
Thorac Cancer, 2018 Aug 29; 9(10). PMID: 30151899    Free PMC article.
Identifying neoantigens for use in immunotherapy.
Sharon Hutchison, Antonia L Pritchard.
Mamm Genome, 2018 Sep 01; 29(11-12). PMID: 30167844    Free PMC article.
B cells and antibody production in melanoma.
Jessica Da Gama Duarte, Janique M Peyper, Jonathan M Blackburn.
Mamm Genome, 2018 Sep 05; 29(11-12). PMID: 30178304
Genetics and biology of prostate cancer.
Guocan Wang, Di Zhao, Denise J Spring, Ronald A DePinho.
Genes Dev, 2018 Sep 06; 32(17-18). PMID: 30181359    Free PMC article.
Evaluation of anti-PD-1-based therapy against triple-negative breast cancer patient-derived xenograft tumors engrafted in humanized mouse models.
Roberto R Rosato, Daniel Dávila-González, +6 authors, Jenny C Chang.
Breast Cancer Res, 2018 Sep 07; 20(1). PMID: 30185216    Free PMC article.
Dendritic cell vaccines for melanoma: past, present and future.
Robert O Dillman, Gabriel I Nistor, Andrew N Cornforth.
Melanoma Manag, 2016 Dec 01; 3(4). PMID: 30190899    Free PMC article.
An update on the relevance of vaccine research for the treatment of metastatic melanoma.
Robert O Dillman.
Melanoma Manag, 2018 Sep 08; 4(4). PMID: 30190926    Free PMC article.
Immuno-Oncology: Emerging Targets and Combination Therapies.
Henry T Marshall, Mustafa B A Djamgoz.
Front Oncol, 2018 Sep 08; 8. PMID: 30191140    Free PMC article.
Highly Cited. Review.
Metallic Nanoparticles for Cancer Immunotherapy.
Emily Reiser Evans, Pallavi Bugga, Vishwaratn Asthana, Rebekah Drezek.
Mater Today (Kidlington), 2018 Sep 11; 21(6). PMID: 30197553    Free PMC article.
TSNAdb: A Database for Tumor-specific Neoantigens from Immunogenomics Data Analysis.
Jingcheng Wu, Wenyi Zhao, +4 authors, Shuqing Chen.
Genomics Proteomics Bioinformatics, 2018 Sep 18; 16(4). PMID: 30223042    Free PMC article.
Drug resistance and new therapies in colorectal cancer.
Kevin Van der Jeught, Han-Chen Xu, +2 authors, Guang Ji.
World J Gastroenterol, 2018 Sep 20; 24(34). PMID: 30228778    Free PMC article.
Highly Cited. Review.
Systematic identification of cancer-specific MHC-binding peptides with RAVEN.
Michaela C Baldauf, Julia S Gerke, +27 authors, Thomas G P Grünewald.
Oncoimmunology, 2018 Sep 20; 7(9). PMID: 30228952    Free PMC article.
Targeting Toll-Like Receptors for Cancer Therapy.
Marc J Braunstein, John Kucharczyk, Sylvia Adams.
Target Oncol, 2018 Sep 20; 13(5). PMID: 30229471
Not All Immune Checkpoints Are Created Equal.
Annika De Sousa Linhares, Judith Leitner, Katharina Grabmeier-Pfistershammer, Peter Steinberger.
Front Immunol, 2018 Sep 21; 9. PMID: 30233564    Free PMC article.
Highly Cited. Review.
Genomic Characterization of Six Virus-Associated Cancers Identifies Changes in the Tumor Immune Microenvironment and Altered Genetic Programs.
Frederick S Varn, Evelien Schaafsma, Yue Wang, Chao Cheng.
Cancer Res, 2018 Sep 27; 78(22). PMID: 30254145    Free PMC article.
RNA editing derived epitopes function as cancer antigens to elicit immune responses.
Minying Zhang, Jens Fritsche, +22 authors, Patrick Hwu.
Nat Commun, 2018 Sep 27; 9(1). PMID: 30254248    Free PMC article.
A neoepitope derived from a novel human germline APC gene mutation in familial adenomatous polyposis shows selective immunogenicity.
Snigdha Majumder, Rakshit Shah, +14 authors, Arati Khanna-Gupta.
PLoS One, 2018 Sep 27; 13(9). PMID: 30256815    Free PMC article.
Liposomal Formulations to Modulate the Tumour Microenvironment and Antitumour Immune Response.
Roger Gilabert-Oriol, Gemma M Ryan, +3 authors, Marcel B Bally.
Int J Mol Sci, 2018 Sep 29; 19(10). PMID: 30261606    Free PMC article.
Tricarbocyanine N-triazoles: the scaffold-of-choice for long-term near-infrared imaging of immune cells in vivo.
Richard J Mellanby, Jamie I Scott, +5 authors, Marc Vendrell.
Chem Sci, 2018 Oct 06; 9(36). PMID: 30288247    Free PMC article.
Role of Hypoxic Stress in Regulating Tumor Immunogenicity, Resistance and Plasticity.
Stéphane Terry, Rania Faouzi Zaarour, +6 authors, Salem Chouaib.
Int J Mol Sci, 2018 Oct 12; 19(10). PMID: 30301213    Free PMC article.
Emerging role of precision medicine in biliary tract cancers.
James M Bogenberger, Thomas T DeLeon, +2 authors, Mitesh J Borad.
NPJ Precis Oncol, 2018 Oct 12; 2. PMID: 30302397    Free PMC article.
[Immunotherapy for locally advanced and metastasized bladder cancer].
W Loidl, F Luger.
Urologe A, 2018 Oct 12; 57(11). PMID: 30302494
Checkpoint Inhibition in Myeloma: Opportunities and Challenges.
Federica Costa, Rituparna Das, +2 authors, Madhav V Dhodapkar.
Front Immunol, 2018 Oct 16; 9. PMID: 30319648    Free PMC article.
Combining STING-based neoantigen-targeted vaccine with checkpoint modulators enhances antitumor immunity in murine pancreatic cancer.
Heather L Kinkead, Alexander Hopkins, +12 authors, Neeha Zaidi.
JCI Insight, 2018 Oct 20; 3(20). PMID: 30333318    Free PMC article.
Unique true predicted neoantigens (TPNAs) correlates with anti-tumor immune control in HCC patients.
Annacarmen Petrizzo, Maria Tagliamonte, +9 authors, Luigi Buonaguro.
J Transl Med, 2018 Oct 21; 16(1). PMID: 30340600    Free PMC article.
Establishment of a novel platform cell line for efficient and precise evaluation of T cell receptor functional avidity.
Soyoko Morimoto, Fumihiro Fujiki, +12 authors, Haruo Sugiyama.
Oncotarget, 2018 Oct 23; 9(75). PMID: 30344927    Free PMC article.
Homology-Directed Repair and the Role of BRCA1, BRCA2, and Related Proteins in Genome Integrity and Cancer.
Chun-Chin Chen, Weiran Feng, +2 authors, Maria Jasin.
Annu Rev Cancer Biol, 2018 Oct 23; 2. PMID: 30345412    Free PMC article.
Highly Cited.
Identification and validation of a tumor-infiltrating Treg transcriptional signature conserved across species and tumor types.
Angela M Magnuson, Evgeny Kiner, +8 authors, Christophe Benoist.
Proc Natl Acad Sci U S A, 2018 Oct 24; 115(45). PMID: 30348759    Free PMC article.
Isolation and characterization of NY-ESO-1-specific T cell receptors restricted on various MHC molecules.
Michael T Bethune, Xiao-Hua Li, +15 authors, David Baltimore.
Proc Natl Acad Sci U S A, 2018 Oct 24; 115(45). PMID: 30348802    Free PMC article.
[Mode of action, new targets and potential biomarkers in modern immunotherapy].
J Bedke, V Stühler, T Todenhöfer, A Stenzl.
Urologe A, 2018 Oct 24; 57(11). PMID: 30350128
Targeting macrophages: therapeutic approaches in cancer.
Luca Cassetta, Jeffrey W Pollard.
Nat Rev Drug Discov, 2018 Oct 27; 17(12). PMID: 30361552
Highly Cited. Review.
Next-Generation in vivo Modeling of Human Cancers.
Gaetano Gargiulo.
Front Oncol, 2018 Oct 27; 8. PMID: 30364119    Free PMC article.
Exploring optimal sequencing of radiation and immunotherapy combinations.
Andrew J Gunderson, Kristina H Young.
Adv Radiat Oncol, 2018 Oct 30; 3(4). PMID: 30370348    Free PMC article.
The DNA damage response in immunotherapy and radiation.
Robert M Samstein, Nadeem Riaz.
Adv Radiat Oncol, 2018 Oct 30; 3(4). PMID: 30370352    Free PMC article.
Predicting T cell recognition of MHC class I restricted neoepitopes.
Zeynep Koşaloğlu-Yalçın, Manasa Lanka, +8 authors, Bjoern Peters.
Oncoimmunology, 2018 Nov 01; 7(11). PMID: 30377561    Free PMC article.
T cell receptor richness in peripheral blood increases after cetuximab therapy and correlates with therapeutic response.
Benjamin A Kansy, Gulidanna Shayan, +8 authors, Robert L Ferris.
Oncoimmunology, 2018 Nov 01; 7(11). PMID: 30377562    Free PMC article.
CART Immunotherapy: Development, Success, and Translation to Malignant Gliomas and Other Solid Tumors.
Anna C Filley, Mario Henriquez, Mahua Dey.
Front Oncol, 2018 Nov 06; 8. PMID: 30386740    Free PMC article.
Immunotherapy for Urothelial Carcinoma: Current Evidence and Future Directions.
Abhishek Tripathi, Elizabeth R Plimack.
Curr Urol Rep, 2018 Nov 09; 19(12). PMID: 30406502
Mismatch repair-based stratification for immune checkpoint blockade therapy.
Lihong Zhang, Yang Peng, Guang Peng.
Am J Cancer Res, 2018 Nov 13; 8(10). PMID: 30416850    Free PMC article.
The Central Role of Inflammation Associated with Checkpoint Inhibitor Treatments.
Cristina Vajaitu, Carmen Cristina Draghici, +6 authors, Vlad Mihai Voiculescu.
J Immunol Res, 2018 Nov 13; 2018. PMID: 30417020    Free PMC article.
Chimeric-Antigen-Receptor (CAR) T Cells and the Factors Influencing their Therapeutic Efficacy.
Victoria G Kravets, Yi Zhang, Hongxing Sun.
J Immunol Res Ther, 2017 Jun 01; 2(1). PMID: 30443604    Free PMC article.
Epigenetic Heterogeneity in Human Colorectal Tumors Reveals Preferential Conservation And Evidence of Immune Surveillance.
Marc D Ryser, Ming Yu, +2 authors, Darryl Shibata.
Sci Rep, 2018 Nov 25; 8(1). PMID: 30470817    Free PMC article.
The role of neoantigen in immune checkpoint blockade therapy.
Ming Yi, Shuang Qin, +3 authors, Kongming Wu.
Exp Hematol Oncol, 2018 Nov 27; 7. PMID: 30473928    Free PMC article.
Highly Cited. Review.
Inactivation of DNA repair-prospects for boosting cancer immune surveillance.
Anna Truini, Giovanni Germano, Alberto Bardelli.
Genome Med, 2018 Nov 30; 10(1). PMID: 30486892    Free PMC article.
Tumor mutational burden assessment as a predictive biomarker for immunotherapy in lung cancer patients: getting ready for prime-time or not?
Simon Heeke, Paul Hofman.
Transl Lung Cancer Res, 2018 Dec 07; 7(6). PMID: 30505707    Free PMC article.
Clinical utility of tumor mutational burden in patients with non-small cell lung cancer treated with immunotherapy.
Lizza E Hendriks, Etienne Rouleau, Benjamin Besse.
Transl Lung Cancer Res, 2018 Dec 07; 7(6). PMID: 30505709    Free PMC article.
Methods of measurement for tumor mutational burden in tumor tissue.
Bárbara Meléndez, Claude Van Campenhout, +3 authors, Nicky D'Haene.
Transl Lung Cancer Res, 2018 Dec 07; 7(6). PMID: 30505710    Free PMC article.
Highly Cited. Review.
Measuring tumor mutation burden in non-small cell lung cancer: tissue versus liquid biopsy.
Francesca Fenizia, Raffaella Pasquale, +3 authors, Nicola Normanno.
Transl Lung Cancer Res, 2018 Dec 07; 7(6). PMID: 30505711    Free PMC article.
Tumor mutational burden in non-small cell lung cancer-the pathologist's point of view.
Frédérique Penault-Llorca, Nina Radosevic-Robin.
Transl Lung Cancer Res, 2018 Dec 07; 7(6). PMID: 30505716    Free PMC article.
IL-39 acts as a friend to pancreatic cancer.
Alicia A Manning, Lei Zhao, +8 authors, Yujiang Fang.
Med Oncol, 2018 Dec 07; 36(1). PMID: 30506430
Autophagosome-based strategy to monitor apparent tumor-specific CD8 T cells in patients with prostate cancer.
Rieneke van de Ven, Traci L Hilton, +8 authors, Bernard A Fox.
Oncoimmunology, 2018 Dec 14; 7(12). PMID: 30524883    Free PMC article.
Responsiveness to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade in SB28 and GL261 mouse glioma models.
Vassilis Genoud, Eliana Marinari, +5 authors, Paul R Walker.
Oncoimmunology, 2018 Dec 14; 7(12). PMID: 30524896    Free PMC article.
Integrated analysis of the immunological and genetic status in and across cancer types: impact of mutational signatures beyond tumor mutational burden.
Jan Budczies, Anja Seidel, +7 authors, Carsten Denkert.
Oncoimmunology, 2018 Dec 14; 7(12). PMID: 30524909    Free PMC article.
Trial watch: Peptide-based vaccines in anticancer therapy.
Lucillia Bezu, Oliver Kepp, +6 authors, Lorenzo Galluzzi.
Oncoimmunology, 2018 Dec 14; 7(12). PMID: 30524907    Free PMC article.
Highly Cited. Review.
The molecular landscape of glioma in patients with Neurofibromatosis 1.
Fulvio D'Angelo, Michele Ceccarelli, +44 authors, Antonio Iavarone.
Nat Med, 2018 Dec 12; 25(1). PMID: 30531922    Free PMC article.
Highly Cited.
The current status of immunotherapy for cervical cancer.
Cecilia Orbegoso, Krithika Murali, Susana Banerjee.
Rep Pract Oncol Radiother, 2018 Dec 12; 23(6). PMID: 30534022    Free PMC article.
Promises and Pitfalls in the Use of PD-1/PD-L1 Inhibitors in Multiple Myeloma.
Stefania Oliva, Rossella Troia, +2 authors, Francesca Gay.
Front Immunol, 2018 Dec 13; 9. PMID: 30538704    Free PMC article.
Liposomal Nanostructures for Drug Delivery in Gastrointestinal Cancers.
Manisit Das, Leaf Huang.
J Pharmacol Exp Ther, 2018 Dec 14; 370(3). PMID: 30541917    Free PMC article.
HER2 signaling regulates the tumor immune microenvironment and trastuzumab efficacy.
Tiziana Triulzi, Luca Forte, +6 authors, Elda Tagliabue.
Oncoimmunology, 2018 Dec 14; 8(1). PMID: 30546951    Free PMC article.
A B cell-derived gene expression signature associates with an immunologically active tumor microenvironment and response to immune checkpoint blockade therapy.
Frederick S Varn, Yue Wang, Chao Cheng.
Oncoimmunology, 2018 Dec 14; 8(1). PMID: 30546953    Free PMC article.
Fates of CD8+ T cells in Tumor Microenvironment.
Nomathamsanqa Resegofetse Maimela, Shasha Liu, Yi Zhang.
Comput Struct Biotechnol J, 2018 Dec 26; 17. PMID: 30581539    Free PMC article.
Highly Cited. Review.
Targeting natural killer cells in solid tumors.
Guillaume Habif, Adeline Crinier, +2 authors, Emilie Narni-Mancinelli.
Cell Mol Immunol, 2019 Mar 27; 16(5). PMID: 30911118    Free PMC article.
Highly Cited. Review.
Targeting immune cells for cancer therapy.
Sin Yee Gun, Sharon Wei Ling Lee, Je Lin Sieow, Siew Cheng Wong.
Redox Biol, 2019 Mar 29; 25. PMID: 30917934    Free PMC article.
Highly Cited. Review.
Bladder cancer, a unique model to understand cancer immunity and develop immunotherapy approaches.
Dongkui Song, Thomas Powles, +3 authors, Yong-Jie Lu.
J Pathol, 2019 May 19; 249(2). PMID: 31102277    Free PMC article.
CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers.
Collin Tokheim, Rachel Karchin.
Cell Syst, 2019 Jun 17; 9(1). PMID: 31202631    Free PMC article.
Mechanisms of immunogenicity in colorectal cancer.
T O Sillo, A D Beggs, D G Morton, G Middleton.
Br J Surg, 2019 Jun 20; 106(10). PMID: 31216061    Free PMC article.
Alternative tumour-specific antigens.
Christof C Smith, Sara R Selitsky, +3 authors, Jonathan S Serody.
Nat Rev Cancer, 2019 Jul 07; 19(8). PMID: 31278396    Free PMC article.
Highly Cited. Review.
Immunotherapy for Colorectal Cancer: A Review of Current and Novel Therapeutic Approaches.
Aaron J Franke, William Paul Skelton, +5 authors, Thomas J George.
J Natl Cancer Inst, 2019 Jul 20; 111(11). PMID: 31322663    Free PMC article.
Supplementary granulocyte macrophage colony-stimulating factor to chemotherapy and programmed death-ligand 1 blockade decreases local recurrence after surgery in bladder cancer.
Makito Miyake, Shunta Hori, +12 authors, Kiyohide Fujimoto.
Cancer Sci, 2019 Aug 07; 110(10). PMID: 31385407    Free PMC article.
Engineering patient-specific cancer immunotherapies.
Lindsay Scheetz, Kyung Soo Park, +4 authors, James J Moon.
Nat Biomed Eng, 2019 Aug 14; 3(10). PMID: 31406259    Free PMC article.
Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model.
Jayanth S Shankara Narayanan, Partha Ray, +6 authors, Rebekah R White.
Cancer Immunol Res, 2019 Aug 15; 7(10). PMID: 31409607    Free PMC article.
Existing and Emerging Biomarkers for Immune Checkpoint Immunotherapy in Solid Tumors.
Sanjeevani Arora, Rodion Velichinskii, +6 authors, Yanis Boumber.
Adv Ther, 2019 Aug 15; 36(10). PMID: 31410780    Free PMC article.
Novel Biomarkers for Personalized Cancer Immunotherapy.
Yoshitaro Shindo, Shoichi Hazama, +2 authors, Hiroaki Nagano.
Cancers (Basel), 2019 Aug 25; 11(9). PMID: 31443339    Free PMC article.
Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood.
Songming Peng, Jesse M Zaretsky, +20 authors, James R Heath.
Cell Rep, 2019 Sep 05; 28(10). PMID: 31484081    Free PMC article.
Panoptic View of Prognostic Models for Personalized Breast Cancer Management.
Geetanjali Saini, Karuna Mittal, +3 authors, Ritu Aneja.
Cancers (Basel), 2019 Sep 11; 11(9). PMID: 31500225    Free PMC article.
Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade.
Andrew Georgiadis, Jennifer N Durham, +16 authors, Mark Sausen.
Clin Cancer Res, 2019 Sep 12; 25(23). PMID: 31506389    Free PMC article.
Direct Detection and Quantification of Neoantigens.
Qing Wang, Jacqueline Douglass, +7 authors, Bert Vogelstein.
Cancer Immunol Res, 2019 Sep 19; 7(11). PMID: 31527070    Free PMC article.
Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens.
Christine E Nelson, Emily A Thompson, +6 authors, Vaiva Vezys.
Cell Rep, 2019 Sep 19; 28(12). PMID: 31533033    Free PMC article.
LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly.
Jan Attig, George R Young, +6 authors, George Kassiotis.
Genome Res, 2019 Sep 21; 29(10). PMID: 31537638    Free PMC article.
Conceptual Development of Immunotherapeutic Approaches to Gastrointestinal Cancer.
Bilikis Aderonke Abolarinwa, Ridwan Babatunde Ibrahim, Yen-Hua Huang.
Int J Mol Sci, 2019 Sep 22; 20(18). PMID: 31540435    Free PMC article.
ALK and RET Inhibitors Promote HLA Class I Antigen Presentation and Unmask New Antigens within the Tumor Immunopeptidome.
Claire Y Oh, Martin G Klatt, +7 authors, David A Scheinberg.
Cancer Immunol Res, 2019 Sep 22; 7(12). PMID: 31540894    Free PMC article.
Tumour Microenvironment and Immune Evasion in EGFR Addicted NSCLC: Hurdles and Possibilities.
Antonio Santaniello, Fabiana Napolitano, +5 authors, Roberto Bianco.
Cancers (Basel), 2019 Sep 27; 11(10). PMID: 31554160    Free PMC article.
Expression of Programmed Cell Death-Ligands in Hepatocellular Carcinoma: Correlation With Immune Microenvironment and Survival Outcomes.
Haotian Liao, Wen Chen, +5 authors, Kunlin Xie.
Front Oncol, 2019 Oct 02; 9. PMID: 31572677    Free PMC article.
A case report of immune checkpoint inhibitor nivolumab combined with anti-angiogenesis agent anlotinib for advanced esophageal squamous cell carcinoma.
Yong Tang, Zhu'an Ou, Zhifang Yao, Guibin Qiao.
Medicine (Baltimore), 2019 Oct 03; 98(40). PMID: 31577707    Free PMC article.
RNA Transcription and Splicing Errors as a Source of Cancer Frameshift Neoantigens for Vaccines.
Luhui Shen, Jian Zhang, +2 authors, Stephen Albert Johnston.
Sci Rep, 2019 Oct 04; 9(1). PMID: 31578439    Free PMC article.
Prognostic Factors and Biomarkers of Responses to Immune Checkpoint Inhibitors in Lung Cancer.
Andrea Bianco, Fabio Perrotta, +3 authors, Raffaele De Palma.
Int J Mol Sci, 2019 Oct 09; 20(19). PMID: 31590386    Free PMC article.
Low-grade glioma harbors few CD8 T cells, which is accompanied by decreased expression of chemo-attractants, not immunogenic antigens.
Bas Weenink, Kaspar Draaisma, +4 authors, Pim J French.
Sci Rep, 2019 Oct 12; 9(1). PMID: 31601888    Free PMC article.
Neo-antigen specific T cell responses indicate the presence of metastases before imaging.
V S Fear, C A Forbes, +7 authors, B W S Robinson.
Sci Rep, 2019 Oct 12; 9(1). PMID: 31601975    Free PMC article.
Liver graft rejection following immune checkpoint inhibitors treatment: a review.
Bo Hu, Xiao-Bo Yang, Xin-Ting Sang.
Med Oncol, 2019 Oct 13; 36(11). PMID: 31605245
Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity.
Guangchuan Wang, Ryan D Chow, +12 authors, Sidi Chen.
Nat Immunol, 2019 Oct 16; 20(11). PMID: 31611701    Free PMC article.
NK Cell-Fc Receptors Advance Tumor Immunotherapy.
Emilio Sanseviero.
J Clin Med, 2019 Oct 17; 8(10). PMID: 31614774    Free PMC article.
Tumor-derived extracellular vesicles: molecular parcels that enable regulation of the immune response in cancer.
Colin Sheehan, Crislyn D'Souza-Schorey.
J Cell Sci, 2019 Oct 17; 132(20). PMID: 31615844    Free PMC article.
TLR9 acts as a sensor for tumor-released DNA to modulate anti-tumor immunity after chemotherapy.
Tae Heung Kang, Chih-Ping Mao, +7 authors, Chien-Fu Hung.
J Immunother Cancer, 2019 Oct 18; 7(1). PMID: 31619293    Free PMC article.
The Clinicopathological and Prognostic Value of PD-L1 Expression in Cholangiocarcinoma: A Meta-Analysis.
Gang Xu, Lejia Sun, +6 authors, Yilei Mao.
Front Oncol, 2019 Oct 18; 9. PMID: 31620360    Free PMC article.
Monalizumab: inhibiting the novel immune checkpoint NKG2A.
Thorbald van Hall, Pascale André, +6 authors, Eric Vivier.
J Immunother Cancer, 2019 Oct 19; 7(1). PMID: 31623687    Free PMC article.
Decreased IFIT2 Expression In Human Non-Small-Cell Lung Cancer Tissues Is Associated With Cancer Progression And Poor Survival Of The Patients.
Wenya Su, Wenlu Xiao, +5 authors, Zhigang Wang.
Onco Targets Ther, 2019 Oct 22; 12. PMID: 31632065    Free PMC article.
Blood tumor mutational burden: are we ready for clinical implementation?
Claude Van Campenhout, Bárbara Meléndez, +2 authors, Nicky D'Haene.
J Thorac Dis, 2019 Oct 22; 11(Suppl 15). PMID: 31632782    Free PMC article.
MiRNA expression patterns are associated with tumor mutational burden in lung adenocarcinoma.
Yufeng Lv, Zhong Huang, +5 authors, Zihai Xu.
Oncoimmunology, 2019 Oct 28; 8(10). PMID: 31646073    Free PMC article.
The impact of CTLA-4 blockade and interferon-α on clonality of T-cell repertoire in the tumor microenvironment and peripheral blood of metastatic melanoma patients.
Arjun Khunger, Julie A Rytlewski, +2 authors, Ahmad A Tarhini.
Oncoimmunology, 2019 Oct 28; 8(11). PMID: 31646098    Free PMC article.
Analysis of tumour ecological balance reveals resource-dependent adaptive strategies of ovarian cancer.
Sidra Nawaz, Nicholas A Trahearn, +4 authors, Yinyin Yuan.
EBioMedicine, 2019 Oct 28; 48. PMID: 31648981    Free PMC article.
Moving Immunoprevention Beyond Virally Mediated Malignancies: Do We Need to Link It to Early Detection?
Madhav V Dhodapkar, Kavita M Dhodapkar.
Front Immunol, 2019 Oct 28; 10. PMID: 31649683    Free PMC article.
Impact of clinicopathological features on the efficacy of immune checkpoint inhibitors plus conventional treatment in patients with advanced lung cancer.
Guanghui Gao, Meng Qiao, +8 authors, Caicun Zhou.
J Thorac Dis, 2019 Oct 28; 11(9). PMID: 31656652    Free PMC article.
pTuneos: prioritizing tumor neoantigens from next-generation sequencing data.
Chi Zhou, Zhiting Wei, +8 authors, Qi Liu.
Genome Med, 2019 Nov 02; 11(1). PMID: 31666118    Free PMC article.
Red blood cell-derived nanoerythrosome for antigen delivery with enhanced cancer immunotherapy.
Xiao Han, Shufang Shen, +6 authors, Chao Wang.
Sci Adv, 2019 Nov 05; 5(10). PMID: 31681841    Free PMC article.
Endogenous T cells prevent tumor immune escape following adoptive T cell therapy.
Scott R Walsh, Boris Simovic, +7 authors, Yonghong Wan.
J Clin Invest, 2019 Nov 05; 129(12). PMID: 31682239    Free PMC article.
Nuclear mechanosensing.
Yuntao Xia, Charlotte R Pfeifer, +2 authors, Jerome Irianto.
Emerg Top Life Sci, 2019 Nov 07; 2(5). PMID: 31693005    Free PMC article.
Comprehensive characterization of the alternative splicing landscape in head and neck squamous cell carcinoma reveals novel events associated with tumorigenesis and the immune microenvironment.
Zhi-Xuan Li, Zi-Qi Zheng, +13 authors, Ying Sun.
Theranostics, 2019 Nov 07; 9(25). PMID: 31695792    Free PMC article.
Single-cell protein profiling in microchambers with barcoded beads.
Lucas Armbrecht, Rafael Sebastian Müller, Jonas Nikoloff, Petra Stephanie Dittrich.
Microsyst Nanoeng, 2019 Nov 09; 5. PMID: 31700673    Free PMC article.
Immunogenicity of Del19 EGFR mutations in Chinese patients affected by lung adenocarcinoma.
Deng Pan, Dapeng Zhou, +4 authors, Yanyan Lou.
BMC Immunol, 2019 Nov 15; 20(1). PMID: 31722672    Free PMC article.
Biomimetic Nanoparticle Vaccines for Cancer Therapy.
Ashley V Kroll, Yao Jiang, +3 authors, Liangfang Zhang.
Adv Biosyst, 2019 Nov 16; 3(1). PMID: 31728404    Free PMC article.
The Immunogenicity and Anti-tumor Efficacy of a Rationally Designed Neoantigen Vaccine for B16F10 Mouse Melanoma.
Yan Zhang, Zhibing Lin, +3 authors, Rongxiu Li.
Front Immunol, 2019 Nov 22; 10. PMID: 31749795    Free PMC article.
Tumor mutational burden in lung cancer: a systematic literature review.
Connor Willis, Michelle Fiander, +6 authors, David D Stenehjem.
Oncotarget, 2019 Nov 26; 10(61). PMID: 31762941    Free PMC article.
Antigen presentation and tumor immunogenicity in cancer immunotherapy response prediction.
Shixiang Wang, Zaoke He, +2 authors, Xue-Song Liu.
Elife, 2019 Nov 27; 8. PMID: 31767055    Free PMC article.
Immune receptor repertoires in pediatric and adult acute myeloid leukemia.
Jian Zhang, Xihao Hu, +14 authors, X Shirley Liu.
Genome Med, 2019 Nov 28; 11(1). PMID: 31771646    Free PMC article.
Identification and ranking of recurrent neo-epitopes in cancer.
Eric Blanc, Manuel Holtgrewe, +4 authors, Dieter Beule.
BMC Med Genomics, 2019 Nov 30; 12(1). PMID: 31775766    Free PMC article.
Tumor-intrinsic signaling pathways: key roles in the regulation of the immunosuppressive tumor microenvironment.
Li Yang, Aitian Li, Qingyang Lei, Yi Zhang.
J Hematol Oncol, 2019 Nov 30; 12(1). PMID: 31775797    Free PMC article.
Delivery strategies of cancer immunotherapy: recent advances and future perspectives.
Zhongwei Zhao, Liyun Zheng, +3 authors, Jiansong Ji.
J Hematol Oncol, 2019 Nov 30; 12(1). PMID: 31779642    Free PMC article.
MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.
Douglas D Fang, Qiuqiong Tang, +8 authors, Yifan Zhai.
J Immunother Cancer, 2019 Nov 30; 7(1). PMID: 31779710    Free PMC article.
A Comprehensive Survey of Genomic Alterations in Gastric Cancer Reveals Recurrent Neoantigens as Potential Therapeutic Targets.
Chao Chen, Qiming Zhou, +4 authors, Chunmei Shi.
Biomed Res Int, 2019 Nov 30; 2019. PMID: 31781598    Free PMC article.
Immunotherapy - Strategies for Expanding Its Role in the Treatment of All Major Tumor Sites.
Chandan Sanghera, Rohan Sanghera.
Cureus, 2019 Dec 04; 11(10). PMID: 31788395    Free PMC article.
Enhanced Therapeutic Efficacy of a Novel Oncolytic Herpes Simplex Virus Type 2 Encoding an Antibody Against Programmed Cell Death 1.
Yujie Zhu, Xiao Hu, +7 authors, Kaitai Zhang.
Mol Ther Oncolytics, 2019 Dec 04; 15. PMID: 31788554    Free PMC article.
Machine Learning for Cancer Immunotherapies Based on Epitope Recognition by T Cell Receptors.
Anja Mösch, Silke Raffegerst, +2 authors, Dmitrij Frishman.
Front Genet, 2019 Dec 05; 10. PMID: 31798635    Free PMC article.
LTX-315 sequentially promotes lymphocyte-independent and lymphocyte-dependent antitumor effects.
Hsin-Wei Liao, Christopher Garris, +9 authors, Mikael J Pittet.
Cell Stress, 2019 Dec 05; 3(11). PMID: 31799501    Free PMC article.
Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration.
Hye-Jung E Chun, Pascal D Johann, +29 authors, Marcel Kool.
Cell Rep, 2019 Nov 12; 29(8). PMID: 31708418    Free PMC article.
Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients.
Lenka Kasikova, Michal Hensler, +16 authors, Jitka Fucikova.
J Immunother Cancer, 2019 Nov 22; 7(1). PMID: 31747968    Free PMC article.
Combined innate and adaptive immunotherapy overcomes resistance of immunologically cold syngeneic murine neuroblastoma to checkpoint inhibition.
Julie Voeller, Amy K Erbe, +15 authors, Paul M Sondel.
J Immunother Cancer, 2019 Dec 08; 7(1). PMID: 31810498    Free PMC article.
Constrained De Novo Sequencing of neo-Epitope Peptides using Tandem Mass Spectrometry.
Sujun Li, Alex DeCourcy, Haixu Tang.
Res Comput Mol Biol, 2018 Jan 01; 10812. PMID: 31819927    Free PMC article.
The epigenomic landscape of transposable elements across normal human development and anatomy.
Erica C Pehrsson, Mayank N K Choudhary, Vasavi Sundaram, Ting Wang.
Nat Commun, 2019 Dec 12; 10(1). PMID: 31822674    Free PMC article.
Biomimetic Nanotechnology toward Personalized Vaccines.
Jiarong Zhou, Ashley V Kroll, +2 authors, Liangfang Zhang.
Adv Mater, 2019 Jun 18; 32(13). PMID: 31206841    Free PMC article.
Gain of function in somatic TP53 mutations is associated with immune-rich breast tumors and changes in tumor-associated macrophages.
Michael Behring, Ana I Vazquez, +5 authors, Sadeep Shrestha.
Mol Genet Genomic Med, 2019 Oct 23; 7(12). PMID: 31637877    Free PMC article.
Genetic instability as a driver for immune surveillance.
Guim Aguadé-Gorgorió, Ricard Solé.
J Immunother Cancer, 2019 Dec 13; 7(1). PMID: 31829285    Free PMC article.
Artificial Intelligence in Lung Cancer Pathology Image Analysis.
Shidan Wang, Donghan M Yang, +7 authors, Guanghua Xiao.
Cancers (Basel), 2019 Oct 31; 11(11). PMID: 31661863    Free PMC article.
Emerging organoid models: leaping forward in cancer research.
Han Fan, Utkan Demirci, Pu Chen.
J Hematol Oncol, 2019 Dec 31; 12(1). PMID: 31884964    Free PMC article.
Head and Neck Cancers Promote an Inflammatory Transcriptome through Coactivation of Classic and Alternative NF-κB Pathways.
Xinping Yang, Hui Cheng, +11 authors, Zhong Chen.
Cancer Immunol Res, 2019 Oct 19; 7(11). PMID: 31624067    Free PMC article.
Immune Activation in Mismatch Repair-Deficient Carcinogenesis: More Than Just Mutational Rate.
Jason A Willis, Laura Reyes-Uribe, +2 authors, Eduardo Vilar.
Clin Cancer Res, 2019 Aug 07; 26(1). PMID: 31383734    Free PMC article.
Combination Cancer Therapy with Immune Checkpoint Blockade: Mechanisms and Strategies.
Shetal A Patel, Andy J Minn.
Immunity, 2018 Mar 22; 48(3). PMID: 29562193    Free PMC article.
Highly Cited. Review.
Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade.
Nicolas Jacquelot, Takahiro Yamazaki, +30 authors, Laurence Zitvogel.
Cell Res, 2019 Sep 05; 29(10). PMID: 31481761    Free PMC article.
A supramolecular protein chaperone for vaccine delivery.
Zhongyan Wang, Yuna Shang, +6 authors, Jianfeng Liu.
Theranostics, 2020 Jan 07; 10(2). PMID: 31903143    Free PMC article.
Homologous Recombination Repair Deficiency and the Immune Response in Breast Cancer: A Literature Review.
B Pellegrino, A Musolino, +6 authors, C Solinas.
Transl Oncol, 2020 Jan 07; 13(2). PMID: 31901781    Free PMC article.
Neoantigens in Hematological Malignancies-Ultimate Targets for Immunotherapy?
Malte Roerden, Annika Nelde, Juliane S Walz.
Front Immunol, 2020 Jan 11; 10. PMID: 31921218    Free PMC article.
Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses.
Weng In Leong, Rachel Y Ames, +8 authors, Mary J Janatpour.
Oncotarget, 2020 Jan 11; 10(68). PMID: 31921384    Free PMC article.
Maximum Somatic Allele Frequency in Combination With Blood-Based Tumor Mutational Burden to Predict the Efficacy of Atezolizumab in Advanced Non-small Cell Lung Cancer: A Pooled Analysis of the Randomized POPLAR and OAK Studies.
Yu-Tong Chen, Sharvesh Raj Seeruttun, Xiang-Yuan Wu, Zi-Xian Wang.
Front Oncol, 2020 Jan 11; 9. PMID: 31921683    Free PMC article.
Lymphatic vasculature in tumor metastasis and immunobiology.
Xinguo Jiang.
J Zhejiang Univ Sci B, 2019 Jul 19;. PMID: 31317681    Free PMC article.
Fructose-1,6-bisphosphatase loss modulates STAT3-dependent expression of PD-L1 and cancer immunity.
Bo Wang, Yingke Zhou, +3 authors, Haojie Huang.
Theranostics, 2020 Jan 16; 10(3). PMID: 31938049    Free PMC article.
DENDRO: genetic heterogeneity profiling and subclone detection by single-cell RNA sequencing.
Zilu Zhou, Bihui Xu, Andy Minn, Nancy R Zhang.
Genome Biol, 2020 Jan 16; 21(1). PMID: 31937348    Free PMC article.
pMHC Structural Comparisons as a Pivotal Element to Detect and Validate T-Cell Targets for Vaccine Development and Immunotherapy-A New Methodological Proposal.
Priscila Vianna, Marcus F A Mendes, +4 authors, Gustavo F Vieira.
Cells, 2019 Nov 27; 8(12). PMID: 31766602    Free PMC article.
Tumor mutational burden assessed by targeted NGS predicts clinical benefit from immune checkpoint inhibitors in non-small cell lung cancer.
Ilaria Alborelli, Katharina Leonards, +12 authors, Philip Jermann.
J Pathol, 2019 Sep 01; 250(1). PMID: 31471895    Free PMC article.
Automated Flow Synthesis of Tumor Neoantigen Peptides for Personalized Immunotherapy.
Nicholas L Truex, Rebecca L Holden, +11 authors, Bradley L Pentelute.
Sci Rep, 2020 Jan 22; 10(1). PMID: 31959774    Free PMC article.
The Adaptive and Innate Immune Cell Landscape of Uterine Leiomyosarcomas.
Marco Manzoni, Maddalena M Bolognesi, +5 authors, Giorgio Cattoretti.
Sci Rep, 2020 Jan 22; 10(1). PMID: 31959856    Free PMC article.
Preclinical murine tumor models: a structural and functional perspective.
Marion V Guerin, Veronica Finisguerra, +2 authors, Alain Trautmann.
Elife, 2020 Jan 29; 9. PMID: 31990272    Free PMC article.
Biomarkers Predictive of Survival and Response to Immune Checkpoint Inhibitors in Melanoma.
Emanuelle M Rizk, Angelina M Seffens, +5 authors, Yvonne M Saenger.
Am J Clin Dermatol, 2019 Oct 12; 21(1). PMID: 31602560    Free PMC article.
Vaccination with CD47 deficient tumor cells elicits an antitumor immune response in mice.
Yang Li, Mingyou Zhang, +3 authors, Yong-Guang Yang.
Nat Commun, 2020 Jan 31; 11(1). PMID: 31996683    Free PMC article.
Apparent Lack of BRAF Derived HLA Class I Presented Neoantigens Hampers Neoplastic Cell Targeting by CD8+ T Cells in Langerhans Cell Histiocytosis.
Paul G Kemps, Timo C Zondag, +24 authors, Astrid G S van Halteren.
Front Immunol, 2020 Jan 31; 10. PMID: 31998317    Free PMC article.
Identification of a CD8+ T-cell response to a predicted neoantigen in malignant mesothelioma.
Sophie Sneddon, Craig M Rive, +9 authors, Jenette Creaney.
Oncoimmunology, 2020 Feb 01; 9(1). PMID: 32002298    Free PMC article.
Pre-treatment tumor neo-antigen responses in draining lymph nodes are infrequent but predict checkpoint blockade therapy outcome.
Shaokang Ma, Jonathan Chee, +5 authors, Jenette Creaney.
Oncoimmunology, 2020 Feb 01; 9(1). PMID: 32002299    Free PMC article.
Tumour-reactive T cell subsets in the microenvironment of ovarian cancer.
Marie Christine Wulff Westergaard, Rikke Andersen, +9 authors, Inge Marie Svane.
Br J Cancer, 2019 Feb 06; 120(4). PMID: 30718808    Free PMC article.
High Somatic Mutation and Neoantigen Burden Do Not Correlate with Decreased Progression-Free Survival in HCC Patients not Undergoing Immunotherapy.
Angela Mauriello, Roberta Zeuli, +6 authors, Luigi Buonaguro.
Cancers (Basel), 2019 Nov 24; 11(12). PMID: 31756926    Free PMC article.
Cancer Cell Membrane-Coated Nanoparticles for Cancer Management.
Jenna C Harris, Mackenzie A Scully, Emily S Day.
Cancers (Basel), 2019 Nov 27; 11(12). PMID: 31766360    Free PMC article.
Association of the prognostic model iSEND with PD-1/L1 monotherapy outcome in non-small-cell lung cancer.
Wungki Park, Laura Mezquita, +14 authors, Gilberto Lopes.
Br J Cancer, 2019 Nov 26; 122(3). PMID: 31761899    Free PMC article.
Oncogene addiction and tumor mutational burden in non-small-cell lung cancer: Clinical significance and limitations.
Elisabeth Smolle, Katharina Leithner, Horst Olschewski.
Thorac Cancer, 2019 Dec 05; 11(2). PMID: 31799812    Free PMC article.
Neoantigens from the bench to the bedside: new prospective for ovarian cancer immunotherapy.
Chiara Napoletano, Filippo Bellati.
Ann Transl Med, 2020 Feb 06; 7(Suppl 8). PMID: 32016024    Free PMC article.
Mutated RAS: Targeting the "Untargetable" with T Cells.
Praveen D Chatani, James C Yang.
Clin Cancer Res, 2019 Sep 13; 26(3). PMID: 31511296    Free PMC article.
Resistance Mechanism of PD-1/PD-L1 Blockade in the Cancer-Immunity Cycle.
Yuan Zhuang, Chang Liu, Jiaqing Liu, Guang Li.
Onco Targets Ther, 2020 Feb 06; 13. PMID: 32021257    Free PMC article.
Poor clinical outcome in metastatic melanoma is associated with a microRNA-modulated immunosuppressive tumor microenvironment.
Natasha A N Jorge, Jéssica G V Cruz, +3 authors, Mariana Boroni.
J Transl Med, 2020 Feb 07; 18(1). PMID: 32024530    Free PMC article.
APOBEC3B-mediated corruption of the tumor cell immunopeptidome induces heteroclitic neoepitopes for cancer immunotherapy.
Christopher B Driscoll, Matthew R Schuelke, +17 authors, Richard G Vile.
Nat Commun, 2020 Feb 09; 11(1). PMID: 32034147    Free PMC article.
Tumor-Infiltrating Lymphocytes and Prognosis: A Pooled Individual Patient Analysis of Early-Stage Triple-Negative Breast Cancers.
Sherene Loi, Damien Drubay, +19 authors, Stefan Michiels.
J Clin Oncol, 2019 Jan 17; 37(7). PMID: 30650045    Free PMC article.
Highly Cited.
The Slippery Role of Induction Chemotherapy in Head and Neck Cancer: Myth and Reality.
Daris Ferrari, Maria Grazia Ghi, +3 authors, Jerome Fayette.
Front Oncol, 2020 Feb 11; 10. PMID: 32038985    Free PMC article.
Biomimetic Nanoparticles Camouflaged in Cancer Cell Membranes and Their Applications in Cancer Theranostics.
Jiefu Jin, Zaver M Bhujwalla.
Front Oncol, 2020 Feb 11; 9. PMID: 32039028    Free PMC article.
Predictive biomarkers for immune checkpoint blockade and opportunities for combination therapies.
Hongxing Shen, Eddy Shih-Hsin Yang, +4 authors, Lewis Zhichang Shi.
Genes Dis, 2020 Feb 12; 6(3). PMID: 32042863    Free PMC article.
Prognostic Biomarkers for Melanoma Immunotherapy.
Christopher G Twitty, Laura A Huppert, Adil I Daud.
Curr Oncol Rep, 2020 Feb 13; 22(3). PMID: 32048065
Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses.
Anthony E Zamora, Jeremy Chase Crawford, +17 authors, Paul G Thomas.
Sci Transl Med, 2019 Jun 28; 11(498). PMID: 31243155    Free PMC article.
Sequential MR Image-Guided Local Immune Checkpoint Blockade Cancer Immunotherapy Using Ferumoxytol Capped Ultralarge Pore Mesoporous Silica Carriers after Standard Chemotherapy.
Bongseo Choi, Huijin Jung, +3 authors, Dong-Hyun Kim.
Small, 2019 Nov 08; 15(52). PMID: 31697036    Free PMC article.
The double-edged sword of cancer mutations: exploiting neoepitopes for the fight against cancer.
Isabel Alvarado-Cruz, Rithy Meas, +3 authors, Joann Balazs Sweasy.
Mutagenesis, 2019 Dec 28; 35(1). PMID: 31880305    Free PMC article.
Immune Checkpoint Inhibition in Colorectal Cancer: Microsatellite Instability and Beyond.
Romain Cohen, Benoît Rousseau, +3 authors, Thierry André.
Target Oncol, 2019 Dec 02; 15(1). PMID: 31786718
Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.
Elena Galvani, Piyushkumar A Mundra, +19 authors, Richard Marais.
Nat Commun, 2020 Feb 14; 11(1). PMID: 32051401    Free PMC article.
T cell receptor-based cancer immunotherapy: Emerging efficacy and pathways of resistance.
Smita S Chandran, Christopher A Klebanoff.
Immunol Rev, 2019 Jul 30; 290(1). PMID: 31355495    Free PMC article.
Highly Cited. Review.
Immunologic alterations in the pancreatic cancer microenvironment of patients treated with neoadjuvant chemotherapy and radiotherapy.
Matthew R Farren, Layal Sayegh, +12 authors, Gregory B Lesinski.
JCI Insight, 2019 Dec 13; 5(1). PMID: 31830001    Free PMC article.
Expanding the Scope of Immunotherapy in Colorectal Cancer: Current Clinical Approaches and Future Directions.
Malek Kreidieh, Deborah Mukherji, Sally Temraz, Ali Shamseddine.
Biomed Res Int, 2020 Feb 25; 2020. PMID: 32090113    Free PMC article.
Targeting DNA repair in cancer: current state and novel approaches.
Apostolos Klinakis, Dimitris Karagiannis, Theodoros Rampias.
Cell Mol Life Sci, 2019 Oct 16; 77(4). PMID: 31612241
Immune Checkpoint Inhibitor Myocarditis: Pathophysiological Characteristics, Diagnosis, and Treatment.
Nicolas Palaskas, Juan Lopez-Mattei, +2 authors, Anita Deswal.
J Am Heart Assoc, 2020 Jan 22; 9(2). PMID: 31960755    Free PMC article.
Immune Checkpoint Blockade Enhances Shared Neoantigen-Induced T-cell Immunity Directed against Mutated Calreticulin in Myeloproliferative Neoplasms.
Cansu Cimen Bozkus, Vladimir Roudko, +4 authors, Nina Bhardwaj.
Cancer Discov, 2019 Jul 04; 9(9). PMID: 31266769    Free PMC article.
Immunologic Biomarkers and Biomarkers for Immunotherapies in Gastrointestinal Cancer.
Benedikt Martin, Bruno Märkl.
Visc Med, 2019 Jul 18; 35(1). PMID: 31312644    Free PMC article.
Assessment of Tumor Mutational Burden in Pediatric Tumors by Real-Life Whole-Exome Sequencing and In Silico Simulation of Targeted Gene Panels: How the Choice of Method Could Affect the Clinical Decision?
Hana Noskova, Michal Kyr, +10 authors, Ondrej Slaby.
Cancers (Basel), 2020 Jan 23; 12(1). PMID: 31963488    Free PMC article.
Immunotherapy with immune checkpoint inhibitors in colorectal cancer: what is the future beyond deficient mismatch-repair tumours?
Nicolas Huyghe, Paméla Baldin, Marc Van den Eynde.
Gastroenterol Rep (Oxf), 2020 Feb 28; 8(1). PMID: 32104582    Free PMC article.
dbPepNeo: a manually curated database for human tumor neoantigen peptides.
Xiaoxiu Tan, Daixi Li, +7 authors, Lu Xie.
Database (Oxford), 2020 Feb 25; 2020. PMID: 32090262    Free PMC article.
Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response.
Xiang Yu, Yanfeng Dai, +5 authors, Zhihong Zhang.
Nat Commun, 2020 Mar 01; 11(1). PMID: 32111828    Free PMC article.
Immune Escape after Hematopoietic Stem Cell Transplantation (HSCT): From Mechanisms to Novel Therapies.
Paolo Bernasconi, Oscar Borsani.
Cancers (Basel), 2019 Dec 29; 12(1). PMID: 31881776    Free PMC article.
Predicting clinical benefit of immunotherapy by antigenic or functional mutations affecting tumour immunogenicity.
Kwoneel Kim, Hong Sook Kim, +7 authors, Jung Kyoon Choi.
Nat Commun, 2020 Feb 23; 11(1). PMID: 32075964    Free PMC article.
Computational Prediction and Validation of Tumor-Associated Neoantigens.
Vladimir Roudko, Benjamin Greenbaum, Nina Bhardwaj.
Front Immunol, 2020 Mar 03; 11. PMID: 32117226    Free PMC article.
Insights Into Lung Cancer Immune-Based Biology, Prevention, and Treatment.
Sara Saab, Hussein Zalzale, +3 authors, Humam Kadara.
Front Immunol, 2020 Mar 03; 11. PMID: 32117295    Free PMC article.
Engineering Targeting Materials for Therapeutic Cancer Vaccines.
Priscilla S Briquez, Sylvie Hauert, +4 authors, Jeffrey A Hubbell.
Front Bioeng Biotechnol, 2020 Mar 03; 8. PMID: 32117911    Free PMC article.
Low mutation and neoantigen burden and fewer effector tumor infiltrating lymphocytes correlate with breast cancer metastasization to lymph nodes.
Zhigang Wang, Wei Liu, +3 authors, Bailin Zhang.
Sci Rep, 2019 Jan 24; 9(1). PMID: 30670769    Free PMC article.
Real-world evidenceand clinical observations of the treatment of advanced non-small cell lung cancer with PD-1/PD-L1 inhibitors.
Peng Song, Jingcheng Zhang, Congcong Shang, Li Zhang.
Sci Rep, 2019 Mar 14; 9(1). PMID: 30862891    Free PMC article.
A library of Neo Open Reading Frame peptides (NOPs) as a sustainable resource of common neoantigens in up to 50% of cancer patients.
Jan Koster, Ronald H A Plasterk.
Sci Rep, 2019 May 01; 9(1). PMID: 31036835    Free PMC article.
My journey from tyrosine phosphorylation inhibitors to targeted immune therapy as strategies to combat cancer.
Alexander Levitzki, Shoshana Klein.
Proc Natl Acad Sci U S A, 2019 May 12; 116(24). PMID: 31076554    Free PMC article.
Tumor intrinsic immunity related proteins may be novel tumor suppressors in some types of cancer.
Donghai Xiong, Yian Wang, Ming You.
Sci Rep, 2019 Jul 31; 9(1). PMID: 31358815    Free PMC article.
High-Throughput Prediction of MHC Class I and II Neoantigens with MHCnuggets.
Xiaoshan M Shao, Rohit Bhattacharya, +12 authors, Rachel Karchin.
Cancer Immunol Res, 2019 Dec 25; 8(3). PMID: 31871119    Free PMC article.
Correlation of plasma exosomal microRNAs with the efficacy of immunotherapy in EGFR / ALK wild-type advanced non-small cell lung cancer.
Xiao-Xiao Peng, Ruoying Yu, +9 authors, Qing Zhou.
J Immunother Cancer, 2020 Jan 22; 8(1). PMID: 31959728    Free PMC article.
Combination of chemotherapy and PD-1 blockade induces T cell responses to tumor non-mutated neoantigens.
Alessio Grimaldi, Ilenia Cammarata, +22 authors, Vincenzo Barnaba.
Commun Biol, 2020 Feb 27; 3(1). PMID: 32099064    Free PMC article.
Resistance to Checkpoint Inhibition in Cancer Immunotherapy.
Luisa Barrueto, Francheska Caminero, +3 authors, Rahul R Deshmukh.
Transl Oncol, 2020 Mar 03; 13(3). PMID: 32114384    Free PMC article.
Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T-Cell Receptors in High-Risk MYCN-Not-Amplified Human Neuroblastoma.
Jun S Wei, Igor B Kuznetsov, +16 authors, Javed Khan.
Clin Cancer Res, 2018 May 23; 24(22). PMID: 29784674    Free PMC article.
Harnessing Tumor Evolution to Circumvent Resistance.
Katherine L Pogrebniak, Christina Curtis.
Trends Genet, 2018 Jun 16; 34(8). PMID: 29903534    Free PMC article.
Acquired resistance to cancer immunotherapy.
Arianna Draghi, Christopher Aled Chamberlain, Andrew Furness, Marco Donia.
Semin Immunopathol, 2018 Jul 04; 41(1). PMID: 29968044
Emerging predictors of the response to the blockade of immune checkpoints in cancer therapy.
Xiaolei Li, Wenhui Song, +2 authors, Weidong Han.
Cell Mol Immunol, 2018 Jul 14; 16(1). PMID: 30002451    Free PMC article.
Mesenchymal Stem Cells Beyond Regenerative Medicine.
Riam Shammaa, Abed El-Hakim El-Kadiry, Jamilah Abusarah, Moutih Rafei.
Front Cell Dev Biol, 2020 Mar 07; 8. PMID: 32133358    Free PMC article.
Tumor Mutation Burden and Efficacy of EGFR-Tyrosine Kinase Inhibitors in Patients with EGFR-Mutant Lung Cancers.
Michael Offin, Hira Rizvi, +12 authors, Matthew D Hellmann.
Clin Cancer Res, 2018 Jul 27; 25(3). PMID: 30045933    Free PMC article.
Highly Cited.
Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma.
Shelly Kalaora, Yochai Wolf, +30 authors, Yardena Samuels.
Cancer Discov, 2018 Sep 14; 8(11). PMID: 30209080    Free PMC article.
Immune biomarkers for predicting response to adoptive cell transfer as cancer treatment.
Ianthe A E M van Belzen, Can Kesmir.
Immunogenetics, 2018 Sep 21; 71(2). PMID: 30232514    Free PMC article.
Biomaterials for vaccine-based cancer immunotherapy.
Rui Zhang, Margaret M Billingsley, Michael J Mitchell.
J Control Release, 2018 Oct 13; 292. PMID: 30312721    Free PMC article.
High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy.
Matthew M Gubin, Ekaterina Esaulova, +16 authors, Maxim N Artyomov.
Cell, 2018 Oct 23; 175(4). PMID: 30343900    Free PMC article.
Highly Cited.
Neoepitope targets of tumour-infiltrating lymphocytes from patients with pancreatic cancer.
Qingda Meng, Davide Valentini, +7 authors, Markus Maeurer.
Br J Cancer, 2018 Nov 01; 120(1). PMID: 30377343    Free PMC article.
The clinical role of the TME in solid cancer.
Nicolas A Giraldo, Rafael Sanchez-Salas, +8 authors, Catherine Sautès-Fridman.
Br J Cancer, 2018 Nov 11; 120(1). PMID: 30413828    Free PMC article.
Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity.
Scott R Walsh, Donald Bastin, +7 authors, Yonghong Wan.
J Clin Invest, 2018 Nov 14; 129(2). PMID: 30422820    Free PMC article.
High-Throughput Stability Screening of Neoantigen/HLA Complexes Improves Immunogenicity Predictions.
Dylan T Blaha, Scott D Anderson, +4 authors, David M Kranz.
Cancer Immunol Res, 2018 Nov 15; 7(1). PMID: 30425106    Free PMC article.
Immunotherapy for Glioblastoma: Adoptive T-cell Strategies.
Bryan D Choi, Marcela V Maus, Carl H June, John H Sampson.
Clin Cancer Res, 2018 Nov 18; 25(7). PMID: 30446589    Free PMC article.
Network assessment of demethylation treatment in melanoma: Differential transcriptome-methylome and antigen profile signatures.
Zhijie Jiang, Caterina Cinti, +7 authors, Enrico Capobianco.
PLoS One, 2018 Nov 30; 13(11). PMID: 30485296    Free PMC article.
Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells.
Pascale André, Caroline Denis, +27 authors, Eric Vivier.
Cell, 2018 Dec 07; 175(7). PMID: 30503213    Free PMC article.
Highly Cited. Review.
PTEN Hamartoma Tumor Syndrome and Immune Dysregulation.
Marc Eissing, Lise Ripken, +6 authors, Nicoline Hoogerbrugge.
Transl Oncol, 2018 Dec 07; 12(2). PMID: 30504085    Free PMC article.
Accounting for proximal variants improves neoantigen prediction.
Jasreet Hundal, Susanna Kiwala, +8 authors, Malachi Griffith.
Nat Genet, 2018 Dec 05; 51(1). PMID: 30510237    Free PMC article.
Mismatch repair deficiency and aberrations in the Notch and Hedgehog pathways are of prognostic value in patients with endometrial cancer.
Genovefa Polychronidou, Vassiliki Kotoula, +14 authors, George Fountzilas.
PLoS One, 2018 Dec 07; 13(12). PMID: 30521558    Free PMC article.
Clinical significance of ≥ 50% PD-L1 expression with the SP263 monoclonal antibody in non-small cell lung cancer patients.
Wenbin Li, Peng Song, +4 authors, Shugeng Gao.
Thorac Cancer, 2018 Dec 12; 10(2). PMID: 30536734    Free PMC article.
Resident-Memory T Cells in Tissue-Restricted Immune Responses: For Better or Worse?
Karin Steinbach, Ilena Vincenti, Doron Merkler.
Front Immunol, 2018 Dec 18; 9. PMID: 30555489    Free PMC article.
Dendritic Cell Membrane Vesicles for Activation and Maintenance of Antigen-Specific T Cells.
Lukasz J Ochyl, James J Moon.
Adv Healthc Mater, 2018 Dec 20; 8(4). PMID: 30565895    Free PMC article.
Tumor-specific MHC-II expression drives a unique pattern of resistance to immunotherapy via LAG-3/FCRL6 engagement.
Douglas B Johnson, Mellissa J Nixon, +21 authors, Justin M Balko.
JCI Insight, 2018 Dec 21; 3(24). PMID: 30568030    Free PMC article.
Recent updates in cancer immunotherapy: a comprehensive review and perspective of the 2018 China Cancer Immunotherapy Workshop in Beijing.
Zihai Li, Wenru Song, Mark Rubinstein, Delong Liu.
J Hematol Oncol, 2018 Dec 24; 11(1). PMID: 30577797    Free PMC article.
Highly Cited. Review.
DNA Mismatch Repair Deficiency and Immune Checkpoint Inhibitors in Gastrointestinal Cancers.
Juan Ruiz-Bañobre, Ajay Goel.
Gastroenterology, 2018 Dec 24; 156(4). PMID: 30578781    Free PMC article.
Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer.
Monica M Olcina, Nikolas G Balanis, +6 authors, Amato J Giaccia.
Cell Rep, 2018 Dec 28; 25(13). PMID: 30590044    Free PMC article.
A multifactorial model of T cell expansion and durable clinical benefit in response to a PD-L1 inhibitor.
Mark D M Leiserson, Vasilis Syrgkanis, +9 authors, Lester Mackey.
PLoS One, 2019 Jan 01; 13(12). PMID: 30596661    Free PMC article.
Delivery technologies for cancer immunotherapy.
Rachel S Riley, Carl H June, Robert Langer, Michael J Mitchell.
Nat Rev Drug Discov, 2019 Jan 10; 18(3). PMID: 30622344    Free PMC article.
Highly Cited. Review.
Vaccinia virus-mediated cancer immunotherapy: cancer vaccines and oncolytics.
Zong Sheng Guo, Binfeng Lu, +8 authors, David L Bartlett.
J Immunother Cancer, 2019 Jan 11; 7(1). PMID: 30626434    Free PMC article.
Highly Cited. Review.
Integration of microbiology, molecular pathology, and epidemiology: a new paradigm to explore the pathogenesis of microbiome-driven neoplasms.
Tsuyoshi Hamada, Jonathan A Nowak, +2 authors, Shuji Ogino.
J Pathol, 2019 Jan 12; 247(5). PMID: 30632609    Free PMC article.
Highly Cited. Review.
Association of Tumor Microenvironment T-cell Repertoire and Mutational Load with Clinical Outcome after Sequential Checkpoint Blockade in Melanoma.
Erik Yusko, Marissa Vignali, +7 authors, Jeffrey Weber.
Cancer Immunol Res, 2019 Jan 13; 7(3). PMID: 30635271    Free PMC article.
Mutated nucleophosmin 1 as immunotherapy target in acute myeloid leukemia.
Dyantha I van der Lee, Rogier M Reijmers, +13 authors, Marieke Griffioen.
J Clin Invest, 2019 Jan 15; 129(2). PMID: 30640174    Free PMC article.
Highly Cited.
Cellular therapy against public neoantigens.
Paul M Armistead.
J Clin Invest, 2019 Jan 15; 129(2). PMID: 30640175    Free PMC article.
Tumor mutational load predicts survival after immunotherapy across multiple cancer types.
Robert M Samstein, Chung-Han Lee, +54 authors, Luc G T Morris.
Nat Genet, 2019 Jan 16; 51(2). PMID: 30643254    Free PMC article.
Highly Cited.
Broadening the Impact of Immunotherapy to Pancreatic Cancer: Challenges and Opportunities.
Vinod P Balachandran, Gregory L Beatty, Stephanie K Dougan.
Gastroenterology, 2019 Jan 21; 156(7). PMID: 30660727    Free PMC article.
Highly Cited. Review.
Tumor mutational burden standardization initiatives: Recommendations for consistent tumor mutational burden assessment in clinical samples to guide immunotherapy treatment decisions.
Albrecht Stenzinger, Jeffrey D Allen, +4 authors, Manfred Dietel.
Genes Chromosomes Cancer, 2019 Jan 22; 58(8). PMID: 30664300    Free PMC article.
Highly Cited. Review.
Reprogramming responsiveness to checkpoint blockade in dysfunctional CD8 T cells.
Christine E Nelson, Lauren J Mills, +6 authors, Vaiva Vezys.
Proc Natl Acad Sci U S A, 2019 Jan 27; 116(7). PMID: 30679280    Free PMC article.
Cancer neoantigens targeted by adoptive T cell transfer: private no more.
Enrico Lugli, Pia Kvistborg, Giovanni Galletti.
J Clin Invest, 2019 Feb 05; 129(3). PMID: 30714989    Free PMC article.
Breaking tolerance with engineered class I antigen-presenting molecules.
Christopher A Parks, Kalli R Henning, +10 authors, Larry R Pease.
Proc Natl Acad Sci U S A, 2019 Feb 08; 116(8). PMID: 30728302    Free PMC article.
Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells.
Dali Han, Jun Liu, +12 authors, Chuan He.
Nature, 2019 Feb 08; 566(7743). PMID: 30728504    Free PMC article.
Highly Cited.
Pre-fractionation Extends but also Creates a Bias in the Detectable HLA Class Ι Ligandome.
Laura C Demmers, Albert J R Heck, Wei Wu.
J Proteome Res, 2019 Feb 21; 18(4). PMID: 30784271    Free PMC article.
Gynecological Cancers Translational, Research Implementation, and Harmonization: Gynecologic Cancer InterGroup Consensus and Still Open Questions.
Marina Bagnoli, Ting Yan Shi, +17 authors, Delia Mezzanzanica.
Cells, 2019 Mar 01; 8(3). PMID: 30813545    Free PMC article.
Assessment of Blood Tumor Mutational Burden as a Potential Biomarker for Immunotherapy in Patients With Non-Small Cell Lung Cancer With Use of a Next-Generation Sequencing Cancer Gene Panel.
Zhijie Wang, Jianchun Duan, +27 authors, Jie Wang.
JAMA Oncol, 2019 Mar 01; 5(5). PMID: 30816954    Free PMC article.
Highly Cited.
Single-cell RNA sequencing of lung adenocarcinoma reveals heterogeneity of immune response-related genes.
Ke-Yue Ma, Alexandra A Schonnesen, +4 authors, Ning Jiang.
JCI Insight, 2019 Mar 02; 4(4). PMID: 30821712    Free PMC article.
Immunotherapy in Non-Small Cell Lung Cancer: Facts and Hopes.
Deborah B Doroshow, Miguel F Sanmamed, +6 authors, Roy S Herbst.
Clin Cancer Res, 2019 Mar 03; 25(15). PMID: 30824587    Free PMC article.
Highly Cited. Review.
Mutations in DNA repair genes are associated with increased neoantigen burden and a distinct immunophenotype in lung squamous cell carcinoma.
Young Kwang Chae, Jonathan F Anker, +5 authors, Jeffrey H Chuang.
Sci Rep, 2019 Mar 03; 9(1). PMID: 30824826    Free PMC article.
α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas.
E Dodagatta-Marri, D S Meyer, +21 authors, R J Akhurst.
J Immunother Cancer, 2019 Mar 06; 7(1). PMID: 30832732    Free PMC article.
Genomic correlates of response to immune checkpoint blockade.
Tanya E Keenan, Kelly P Burke, Eliezer M Van Allen.
Nat Med, 2019 Mar 08; 25(3). PMID: 30842677    Free PMC article.
Highly Cited. Review.
Autologous tumor cell vaccination combined with systemic CpG-B and IFN-α promotes immune activation and induces clinical responses in patients with metastatic renal cell carcinoma: a phase II trial.
Bas D Koster, Saskia J A M Santegoets, +6 authors, Alfons J M van den Eertwegh.
Cancer Immunol Immunother, 2019 Mar 11; 68(6). PMID: 30852622    Free PMC article.
Clinical Implications of Circulating Tumor DNA Tumor Mutational Burden (ctDNA TMB) in Non-Small Cell Lung Cancer.
Young Kwang Chae, Andrew A Davis, +11 authors, Francis J Giles.
Oncologist, 2019 Mar 15; 24(6). PMID: 30867242    Free PMC article.
Highly Cited.
Mutational load in carotid body tumor.
Anna V Kudryavtseva, Elena N Lukyanova, +16 authors, Anastasiya V Snezhkina.
BMC Med Genomics, 2019 Mar 16; 12(Suppl 2). PMID: 30871634    Free PMC article.
PD-1 and PD-L1 in cancer immunotherapy: clinical implications and future considerations.
Yongshuai Jiang, Ming Chen, Hong Nie, Yuanyang Yuan.
Hum Vaccin Immunother, 2019 Mar 20; 15(5). PMID: 30888929    Free PMC article.
Dynamic host immune response in virus-associated cancers.
Song Cao, Kristine M Wylie, +13 authors, Li Ding.
Commun Biol, 2019 Mar 27; 2. PMID: 30911684    Free PMC article.
CD91 on dendritic cells governs immunosurveillance of nascent, emerging tumors.
Abigail L Sedlacek, Theodore P Younker, +4 authors, Robert J Binder.
JCI Insight, 2019 Apr 05; 4(7). PMID: 30944251    Free PMC article.
How patients with an intact immune system develop head and neck cancer.
Sarah Greene, Priya Patel, Clint T Allen.
Oral Oncol, 2019 Apr 24; 92. PMID: 31010619    Free PMC article.
T cell pathology in skin inflammation.
Robert Sabat, Kerstin Wolk, +2 authors, Kamran Ghoreschi.
Semin Immunopathol, 2019 Apr 28; 41(3). PMID: 31028434    Free PMC article.
Identification of Neoantigen-Reactive Tumor-Infiltrating Lymphocytes in Primary Bladder Cancer.
Vid Leko, Lucas A McDuffie, +6 authors, Yong-Chen Lu.
J Immunol, 2019 May 01; 202(12). PMID: 31036766    Free PMC article.
Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma.
Markus W Löffler, Christopher Mohr, +29 authors, Hans-Georg Rammensee.
Genome Med, 2019 May 02; 11(1). PMID: 31039795    Free PMC article.
Highly Cited.
A Canadian guideline on the use of next-generation sequencing in oncology.
S Yip, A Christofides, +8 authors, A Spatz.
Curr Oncol, 2019 May 03; 26(2). PMID: 31043833    Free PMC article.
NeoPredPipe: high-throughput neoantigen prediction and recognition potential pipeline.
Ryan O Schenck, Eszter Lakatos, +2 authors, Alexander R A Anderson.
BMC Bioinformatics, 2019 May 24; 20(1). PMID: 31117948    Free PMC article.
Aicardi-Goutières syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer.
Sarah K Deasy, Ryo Uehara, +6 authors, Kent W Hunter.
PLoS Genet, 2019 May 28; 15(5). PMID: 31125342    Free PMC article.
Associating somatic mutations to clinical outcomes: a pan-cancer study of survival time.
Paul Little, Dan-Yu Lin, Wei Sun.
Genome Med, 2019 May 30; 11(1). PMID: 31138328    Free PMC article.
Injectable polypeptide hydrogel-based co-delivery of vaccine and immune checkpoint inhibitors improves tumor immunotherapy.
Huijuan Song, Pengxiang Yang, +3 authors, Weiwei Wang.
Theranostics, 2019 Jun 01; 9(8). PMID: 31149045    Free PMC article.
Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma.
Bracha Shraibman, Eilon Barnea, +34 authors, Arie Admon.
Mol Cell Proteomics, 2019 Jun 04; 18(6). PMID: 31154438    Free PMC article.
Cell Fusion in Malignancy: A Cause or Consequence? A Provocateur or Cure?
Jeffrey L Platt, Marilia Cascalho.
Cells, 2019 Jun 19; 8(6). PMID: 31207918    Free PMC article.
Radiation therapy and anti-tumor immunity: exposing immunogenic mutations to the immune system.
Claire Lhuillier, Nils-Petter Rudqvist, +2 authors, Sandra Demaria.
Genome Med, 2019 Jun 22; 11(1). PMID: 31221199    Free PMC article.
Highly Cited. Review.
Bioinformatic Methods and Bridging of Assay Results for Reliable Tumor Mutational Burden Assessment in Non-Small-Cell Lung Cancer.
Han Chang, Ariella Sasson, +7 authors, Joseph Szustakowski.
Mol Diagn Ther, 2019 Jun 30; 23(4). PMID: 31250328    Free PMC article.
Loss of function Cbl-c mutations in solid tumors.
Silvano Rakeem Daniels, Mariya Liyasova, +4 authors, Stanley Lipkowitz.
PLoS One, 2019 Jul 02; 14(7). PMID: 31260484    Free PMC article.
Xenograft and organoid model systems in cancer research.
Margit Bleijs, Marc van de Wetering, Hans Clevers, Jarno Drost.
EMBO J, 2019 Jul 10; 38(15). PMID: 31282586    Free PMC article.
Highly Cited. Review.
Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes.
Andrea Castro, Kivilcim Ozturk, +3 authors, Hannah Carter.
BMC Med Genomics, 2019 Jul 28; 12(Suppl 6). PMID: 31345234    Free PMC article.
Syringeable immunotherapeutic nanogel reshapes tumor microenvironment and prevents tumor metastasis and recurrence.
Chanyoung Song, Hathaichanok Phuengkham, +13 authors, Yong Taik Lim.
Nat Commun, 2019 Aug 23; 10(1). PMID: 31431623    Free PMC article.
Neoantigen vaccine: an emerging tumor immunotherapy.
Miao Peng, Yongzhen Mo, +10 authors, Zhaoyang Zeng.
Mol Cancer, 2019 Aug 25; 18(1). PMID: 31443694    Free PMC article.
Highly Cited. Review.
An agonistic anti-Toll-like receptor 4 monoclonal antibody as an effective adjuvant for cancer immunotherapy.
Hiroki Tsukamoto, Kanae Kubota, +5 authors, Yoshihisa Tomioka.
Immunology, 2019 Sep 14; 158(2). PMID: 31515801    Free PMC article.
DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load.
Hyunchul Jung, Hong Sook Kim, +7 authors, Jung Kyoon Choi.
Nat Commun, 2019 Sep 21; 10(1). PMID: 31537801    Free PMC article.
The Graft-Versus-Leukemia Effect in AML.
Connor Sweeney, Paresh Vyas.
Front Oncol, 2019 Dec 06; 9. PMID: 31803612    Free PMC article.
Cancer Vaccines: Steering T Cells Down the Right Path to Eradicate Tumors.
Patrick A Ott, Catherine J Wu.
Cancer Discov, 2019 Mar 14; 9(4). PMID: 30862723    Free PMC article.
Peptide-TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens.
Geoffrey M Lynn, Christine Sedlik, +27 authors, Robert A Seder.
Nat Biotechnol, 2020 Jan 15; 38(3). PMID: 31932728    Free PMC article.
The Role of Immune Checkpoint Blockade in Uveal Melanoma.
Anja Wessely, Theresa Steeb, +5 authors, Markus Vincent Heppt.
Int J Mol Sci, 2020 Feb 06; 21(3). PMID: 32013269    Free PMC article.
T-Cell Immunotherapies Targeting Histocompatibility and Tumor Antigens in Hematological Malignancies.
Valérie Janelle, Caroline Rulleau, +2 authors, Jean-Sébastien Delisle.
Front Immunol, 2020 Mar 11; 11. PMID: 32153583    Free PMC article.
DNA Microscopy: Optics-free Spatio-genetic Imaging by a Stand-Alone Chemical Reaction.
Joshua A Weinstein, Aviv Regev, Feng Zhang.
Cell, 2019 Jun 25; 178(1). PMID: 31230717    Free PMC article.
Tumor Mutational Burden From Tumor-Only Sequencing Compared With Germline Subtraction From Paired Tumor and Normal Specimens.
Kaushal Parikh, Robert Huether, +5 authors, Aaron S Mansfield.
JAMA Netw Open, 2020 Feb 29; 3(2). PMID: 32108894    Free PMC article.
Tracing the Equilibrium Phase of Cancer Immunoediting in Epidermal Neoplasms via Longitudinal Intravital Imaging.
Bradley J Kubick, Xiying Fan, +2 authors, Dennis R Roop.
J Invest Dermatol, 2019 Sep 23; 140(4). PMID: 31542435    Free PMC article.
Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma.
H J Close, L F Stead, +10 authors, E B Wilson.
Clin Exp Immunol, 2019 Dec 01; 200(1). PMID: 31784984    Free PMC article.
Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes.
Chloe Chong, Markus Müller, +23 authors, Michal Bassani-Sternberg.
Nat Commun, 2020 Mar 12; 11(1). PMID: 32157095    Free PMC article.
Tumor mutational burden is associated with poor outcomes in diffuse glioma.
Lihong Wang, Jia Ge, +10 authors, Tao Luo.
BMC Cancer, 2020 Mar 14; 20(1). PMID: 32164609    Free PMC article.
An immune-centric exploration of BRCA1 and BRCA2 germline mutation related breast and ovarian cancers.
Ewa Przybytkowski, Thomas Davis, +4 authors, Sheida Nabavi.
BMC Cancer, 2020 Mar 14; 20(1). PMID: 32164626    Free PMC article.
An engineered oncolytic virus expressing PD-L1 inhibitors activates tumor neoantigen-specific T cell responses.
Guan Wang, Xi Kang, +5 authors, Si-Yi Chen.
Nat Commun, 2020 Mar 15; 11(1). PMID: 32170083    Free PMC article.
Resistance Mechanisms and Barriers to Successful Immunotherapy for Treating Glioblastoma.
Jason Adhikaree, Julia Moreno-Vicente, +2 authors, Poulam M Patel.
Cells, 2020 Jan 25; 9(2). PMID: 31973059    Free PMC article.
Cytokine-Induced Guanylate Binding Protein 1 (GBP1) Release from Human Ovarian Cancer Cells.
Grazia Carbotti, Andrea Petretto, +6 authors, Marina Fabbi.
Cancers (Basel), 2020 Feb 26; 12(2). PMID: 32093058    Free PMC article.
TCR sequencing analysis of cancer tissues and tumor draining lymph nodes in colorectal cancer patients.
Tatsuo Matsuda, Eisaku Miyauchi, +16 authors, Yusuke Nakamura.
Oncoimmunology, 2019 May 10; 8(6). PMID: 31069156    Free PMC article.
Adoptive Cell Therapy Targeting Neoantigens: A Frontier for Cancer Research.
Zhidong Wang, Yu J Cao.
Front Immunol, 2020 Mar 21; 11. PMID: 32194541    Free PMC article.
Emerging trends in immunotherapy for pediatric sarcomas.
Kyle A Dyson, Brian D Stover, +4 authors, Elias J Sayour.
J Hematol Oncol, 2019 Jul 18; 12(1). PMID: 31311607    Free PMC article.
Tumor neoantigens: from basic research to clinical applications.
Tao Jiang, Tao Shi, +5 authors, Caicun Zhou.
J Hematol Oncol, 2019 Sep 08; 12(1). PMID: 31492199    Free PMC article.
Highly Cited. Review.
Tumor mutation burden derived from small next generation sequencing targeted gene panel as an initial screening method.
Yuan Tang, Yuli Li, +4 authors, Meijuan Huang.
Transl Lung Cancer Res, 2020 Mar 25; 9(1). PMID: 32206555    Free PMC article.
Consensus guidelines for the definition, detection and interpretation of immunogenic cell death.
Lorenzo Galluzzi, Ilio Vitale, +51 authors, Francesco M Marincola.
J Immunother Cancer, 2020 Mar 27; 8(1). PMID: 32209603    Free PMC article.
Relationships Between Immune Landscapes, Genetic Subtypes and Responses to Immunotherapy in Colorectal Cancer.
Emilie Picard, Chris P Verschoor, Grace W Ma, Graham Pawelec.
Front Immunol, 2020 Mar 27; 11. PMID: 32210966    Free PMC article.
Pre-existing heterologous T-cell immunity and neoantigen immunogenicity.
Qibin Leng, Marion Tarbe, Qi Long, Feng Wang.
Clin Transl Immunology, 2020 Mar 27; 9(3). PMID: 32211191    Free PMC article.
Implications of driver genes associated with a high tumor mutation burden identified using next-generation sequencing on immunotherapy in hepatocellular carcinoma.
Li Li, Xiaosong Rao, +9 authors, Liang Jun.
Oncol Lett, 2020 Mar 29; 19(4). PMID: 32218826    Free PMC article.
POLE proofreading defects: Contributions to mutagenesis and cancer.
Vivian S Park, Zachary F Pursell.
DNA Repair (Amst), 2019 Mar 01; 76. PMID: 30818169    Free PMC article.
Endogenous CD4+ T Cells Recognize Neoantigens in Lung Cancer Patients, Including Recurrent Oncogenic KRAS and ERBB2 (Her2) Driver Mutations.
Joshua R Veatch, Brenda L Jesernig, +6 authors, Stanley R Riddell.
Cancer Immunol Res, 2019 May 03; 7(6). PMID: 31043415    Free PMC article.
Impact of panel design and cut-off on tumour mutational burden assessment in metastatic solid tumour samples.
Joanne M Mankor, Marthe S Paats, +7 authors, Martijn P J K Lolkema.
Br J Cancer, 2020 Feb 26; 122(7). PMID: 32094484    Free PMC article.
Extracorporeal Photochemotherapy: Mechanistic Insights Driving Recent Advances and Future Directions.
Brian M Wei, Douglas Hanlon, +4 authors, Richard L Edelson.
Yale J Biol Med, 2020 Apr 01; 93(1). PMID: 32226344    Free PMC article.
Tumor-Infiltrating T Cells From Clear Cell Renal Cell Carcinoma Patients Recognize Neoepitopes Derived From Point and Frameshift Mutations.
Ulla Kring Hansen, Sofie Ramskov, +10 authors, Sine Reker Hadrup.
Front Immunol, 2020 Apr 01; 11. PMID: 32226429    Free PMC article.
Personal tumor antigens in blood malignancies: genomics-directed identification and targeting.
Livius Penter, Catherine J Wu.
J Clin Invest, 2020 Jan 28; 130(4). PMID: 31985488    Free PMC article.
Immune escape and immunotherapy of acute myeloid leukemia.
Luca Vago, Ivana Gojo.
J Clin Invest, 2020 Apr 03; 130(4). PMID: 32235097    Free PMC article.
Integrin ανβ6 Protein Expression and Prognosis in Solid Tumors: A Meta-Analysis.
Alexandra Desnoyers, Carlos González, +3 authors, Alberto Ocaña.
Mol Diagn Ther, 2020 Feb 27; 24(2). PMID: 32100239
Microsatellite instability and its associations with the clinicopathologic characteristics of diffuse large B-cell lymphoma.
Tian Tian, Jiwei Li, +3 authors, Xiaoyan Zhou.
Cancer Med, 2020 Feb 06; 9(7). PMID: 32022486    Free PMC article.
ProGeo-neo: a customized proteogenomic workflow for neoantigen prediction and selection.
Yuyu Li, Guangzhi Wang, +7 authors, Lu Xie.
BMC Med Genomics, 2020 Apr 04; 13(Suppl 5). PMID: 32241270    Free PMC article.
Streamlined selection of cancer antigens for vaccine development through integrative multi-omics and high-content cell imaging.
Ki-Cheol Han, Daechan Park, +10 authors, Mihue Jang.
Sci Rep, 2020 Apr 05; 10(1). PMID: 32245999    Free PMC article.
Mass Spectrometry-Based Identification of MHC-Associated Peptides.
Sachin Kote, Artur Pirog, +2 authors, Irena Dapic.
Cancers (Basel), 2020 Mar 01; 12(3). PMID: 32110973    Free PMC article.
The Current Status of Immune Checkpoint Inhibitors in Neuro-Oncology: A Systematic Review.
Cyrillo G Brahm, Myra E van Linde, +5 authors, Annemiek M E Walenkamp.
Cancers (Basel), 2020 Mar 08; 12(3). PMID: 32143288    Free PMC article.
Correlative Monitoring of Immune Activation and Tissue Damage in Malignant Melanoma-An Algorithm for Identification of Tolerance Breakage During Immune Checkpoint Inhibitor Therapy of Cancer.
Renate U Wahl, Marike Leijs, Arturo Araujo, Albert Rübben.
Int J Mol Sci, 2020 Mar 20; 21(6). PMID: 32188047    Free PMC article.
HLA-Class II Artificial Antigen Presenting Cells in CD4+ T Cell-Based Immunotherapy.
Alexandre Couture, Anthony Garnier, +5 authors, Olivier Toutirais.
Front Immunol, 2019 Jun 04; 10. PMID: 31156634    Free PMC article.
Immunotherapy in Multiple Myeloma.
Cinnie Yentia Soekojo, Melissa Ooi, Sanjay de Mel, Wee Joo Chng.
Cells, 2020 Mar 07; 9(3). PMID: 32138182    Free PMC article.
Immunotherapy, Inflammation and Colorectal Cancer.
Charles Robert Lichtenstern, Rachael Katie Ngu, Shabnam Shalapour, Michael Karin.
Cells, 2020 Mar 08; 9(3). PMID: 32143413    Free PMC article.
Biology and Therapeutic Targets of Colorectal Serrated Adenocarcinoma; Clues for a Histologically Based Treatment against an Aggressive Tumor.
Begoña Alburquerque-González, Fernando F López-Calderón, +3 authors, Pablo Conesa-Zamora.
Int J Mol Sci, 2020 Mar 19; 21(6). PMID: 32183342    Free PMC article.
The Multifactorial Role of PARP-1 in Tumor Microenvironment.
Juan Manuel Martí, Mónica Fernández-Cortés, +4 authors, Francisco Javier Oliver.
Cancers (Basel), 2020 Apr 05; 12(3). PMID: 32245040    Free PMC article.
The Obesity Paradox in Cancer, Tumor Immunology, and Immunotherapy: Potential Therapeutic Implications in Triple Negative Breast Cancer.
Adviti Naik, Arta Monir Monjazeb, Julie Decock.
Front Immunol, 2019 Sep 03; 10. PMID: 31475003    Free PMC article.
Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE gene.
Hitoshi Hino, Akio Shiomi, +9 authors, Ken Yamaguchi.
Cancer Med, 2019 Jun 27; 8(10). PMID: 31240875    Free PMC article.
Immune response characterization of endometrial cancer.
Yuexin Liu.
Oncotarget, 2019 Mar 09; 10(9). PMID: 30847026    Free PMC article.
Efficient identification of neoantigen-specific T-cell responses in advanced human ovarian cancer.
Song Liu, Junko Matsuzaki, +19 authors, Kunle Odunsi.
J Immunother Cancer, 2019 Jun 22; 7(1). PMID: 31221207    Free PMC article.
m6A-binding proteins: the emerging crucial performers in epigenetics.
Yanchun Zhao, Yuanfei Shi, Huafei Shen, Wanzhuo Xie.
J Hematol Oncol, 2020 Apr 12; 13(1). PMID: 32276589    Free PMC article.
14-3-3ζ-A Novel Immunogen Promotes Inflammatory Cytokine Production.
Jenna McGowan, Cara Peter, Saurabh Chattopadhyay, Ritu Chakravarti.
Front Immunol, 2019 Aug 10; 10. PMID: 31396202    Free PMC article.
Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides.
Shiyan Zhu, Kefang Liu, +10 authors, William J Liu.
Front Immunol, 2019 Aug 10; 10. PMID: 31396224    Free PMC article.
Computational Analysis of HLA-presentation of Non-synonymous Recipient Mismatches Indicates Effect on the Risk of Chronic Graft-vs.-Host Disease After Allogeneic HSCT.
Jarmo Ritari, Kati Hyvärinen, +9 authors, Jukka Partanen.
Front Immunol, 2019 Aug 06; 10. PMID: 31379830    Free PMC article.
Prussian blue nanoparticle-based antigenicity and adjuvanticity trigger robust antitumor immune responses against neuroblastoma.
Juliana Cano-Mejia, Michelle L Bookstaver, +2 authors, Rohan Fernandes.
Biomater Sci, 2019 Feb 23; 7(5). PMID: 30789175    Free PMC article.
Functional Differences Between EBV- and CMV-Specific CD8+ T cells Demonstrate Heterogeneity of T cell Dysfunction in CLL.
Tom Hofland, Iris de Weerdt, +8 authors, Sanne H Tonino.
Hemasphere, 2020 Apr 21; 4(2). PMID: 32309780    Free PMC article.
Predictive Markers for the Efficacy of Anti-PD-1/PD-L1 Antibodies in Lung Cancer.
Takehito Shukuya, David P Carbone.
J Thorac Oncol, 2016 Mar 06; 11(7). PMID: 26944305    Free PMC article.
Highly Cited. Review.
Resistance to PD-L1/PD-1 Blockade Immunotherapy. A Tumor-Intrinsic or Tumor-Extrinsic Phenomenon?
Luisa Chocarro de Erauso, Miren Zuazo, +8 authors, David Escors.
Front Pharmacol, 2020 Apr 23; 11. PMID: 32317979    Free PMC article.
Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer.
Samarth Hegde, Varintra E Krisnawan, +16 authors, David G DeNardo.
Cancer Cell, 2020 Mar 19; 37(3). PMID: 32183949    Free PMC article.
The Biogenesis, Biology, and Clinical Significance of Exosomal PD-L1 in Cancer.
Yanyan Tang, Ping Zhang, +10 authors, Qianjin Liao.
Front Immunol, 2020 Apr 24; 11. PMID: 32322256    Free PMC article.
Cell-state dynamics and therapeutic resistance in melanoma from the perspective of MITF and IFNγ pathways.
Xue Bai, David E Fisher, Keith T Flaherty.
Nat Rev Clin Oncol, 2019 Apr 11; 16(9). PMID: 30967646    Free PMC article.
Highly Cited. Review.
PRKDC: new biomarker and drug target for checkpoint blockade immunotherapy.
Kien Thiam Tan, Chun-Nan Yeh, +14 authors, Ming-Huang Chen.
J Immunother Cancer, 2020 Apr 03; 8(1). PMID: 32238472    Free PMC article.
Ushering in Integrated T Cell Repertoire Profiling in Cancer.
Ning Jiang, Alexandra A Schonnesen, Ke-Yue Ma.
Trends Cancer, 2019 Feb 14; 5(2). PMID: 30755308    Free PMC article.
Current Status of Immunotherapies for Treating Pancreatic Cancer.
Annie A Wu, Elizabeth Jaffee, Valerie Lee.
Curr Oncol Rep, 2019 May 19; 21(7). PMID: 31101991
Molecular T-Cell Repertoire Analysis as Source of Prognostic and Predictive Biomarkers for Checkpoint Blockade Immunotherapy.
Ilenia Aversa, Donatella Malanga, Giuseppe Fiume, Camillo Palmieri.
Int J Mol Sci, 2020 Apr 03; 21(7). PMID: 32235561    Free PMC article.
Mapping the spreading routes of lymphatic metastases in human colorectal cancer.
Chong Zhang, Lin Zhang, +10 authors, Haizeng Zhang.
Nat Commun, 2020 Apr 26; 11(1). PMID: 32332722    Free PMC article.
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.
Derin B Keskin, Annabelle J Anandappa, +48 authors, David A Reardon.
Nature, 2018 Dec 21; 565(7738). PMID: 30568305    Free PMC article.
Highly Cited.
Induction of anti-cancer T cell immunity by in situ vaccination using systemically administered nanomedicines.
Geoffrey M Lynn, Richard Laga, Christopher M Jewell.
Cancer Lett, 2019 Jun 12; 459. PMID: 31185250    Free PMC article.
Mast cell-based molecular subtypes and signature associated with clinical outcome in early-stage lung adenocarcinoma.
Xuanwen Bao, Run Shi, Tianyu Zhao, Yanfang Wang.
Mol Oncol, 2020 Mar 17; 14(5). PMID: 32175651    Free PMC article.
Epigenetic driver mutations in ARID1A shape cancer immune phenotype and immunotherapy.
Jing Li, Weichao Wang, +22 authors, Weiping Zou.
J Clin Invest, 2020 Feb 07; 130(5). PMID: 32027624    Free PMC article.
Biomaterial-based platforms for in situ dendritic cell programming and their use in antitumor immunotherapy.
João Calmeiro, Mylène Carrascal, +3 authors, Bruno Miguel Neves.
J Immunother Cancer, 2019 Sep 06; 7(1). PMID: 31484548    Free PMC article.
Cautious optimism-the current role of immunotherapy in gastrointestinal cancers.
S Mendis, S Gill.
Curr Oncol, 2020 May 06; 27(Suppl 2). PMID: 32368175    Free PMC article.
Novel tumor mutation score versus tumor mutation burden in predicting survival after immunotherapy in pan-cancer patients from the MSK-IMPACT cohort.
Yuan Li, Zuhua Chen, Long Wu, Weiping Tao.
Ann Transl Med, 2020 May 13; 8(7). PMID: 32395490    Free PMC article.
Inhibition of the NKp44-PCNA Immune Checkpoint Using a mAb to PCNA.
Kiran Kundu, Susmita Ghosh, +11 authors, Angel Porgador.
Cancer Immunol Res, 2019 Jun 06; 7(7). PMID: 31164357    Free PMC article.
Immunotherapy in Metastatic Colorectal Cancer: Could the Latest Developments Hold the Key to Improving Patient Survival?
Emmanouil Damilakis, Dimitrios Mavroudis, Maria Sfakianaki, John Souglakos.
Cancers (Basel), 2020 Apr 10; 12(4). PMID: 32268531    Free PMC article.
Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer.
Sanghoon Lee, Li Zhao, +43 authors, Anil K Sood.
Cell Rep, 2020 Apr 16; 31(2). PMID: 32294438    Free PMC article.
Current Approaches for Combination Therapy of Cancer: The Role of Immunogenic Cell Death.
Zahra Asadzadeh, Elham Safarzadeh, +7 authors, Behzad Baradaran.
Cancers (Basel), 2020 Apr 29; 12(4). PMID: 32340275    Free PMC article.
High tumor mutation burden is associated with DNA damage repair gene mutation in breast carcinomas.
Ping Mei, C Eric Freitag, +3 authors, Zaibo Li.
Diagn Pathol, 2020 May 13; 15(1). PMID: 32393302    Free PMC article.
Precision immunization: a new trend in human vaccination.
Siyue Jia, Jingxin Li, Yuanbao Liu, Fengcai Zhu.
Hum Vaccin Immunother, 2019 Sep 24; 16(3). PMID: 31545124    Free PMC article.
Heterogeneity of neoantigen landscape between primary lesions and their matched metastases in lung cancer.
Tao Jiang, Ruirui Cheng, +5 authors, Caicun Zhou.
Transl Lung Cancer Res, 2020 May 19; 9(2). PMID: 32420064    Free PMC article.
Medical Gas Plasma Jet Technology Targets Murine Melanoma in an Immunogenic Fashion.
Sander Bekeschus, Ramona Clemen, +3 authors, Anke Schmidt.
Adv Sci (Weinh), 2020 May 23; 7(10). PMID: 32440479    Free PMC article.
Not all cancers are created equal: Tissue specificity in cancer genes and pathways.
Joy J Bianchi, Xin Zhao, Joseph C Mays, Teresa Davoli.
Curr Opin Cell Biol, 2020 Feb 25; 63. PMID: 32092639    Free PMC article.
Integration of Comprehensive Genomic Analysis and Functional Screening of Affected Molecular Pathways to Inform Cancer Therapy.
George Vasmatzis, Minetta C Liu, +12 authors, Panos Z Anastasiadis.
Mayo Clin Proc, 2019 Nov 07; 95(2). PMID: 31685261    Free PMC article.
The premise of personalized immunotherapy for cancer dormancy.
Masoud H Manjili.
Oncogene, 2020 Apr 24; 39(22). PMID: 32322001    Free PMC article.
High expression of immune checkpoints is associated with the TIL load, mutation rate and patient survival in colorectal cancer.
Mara Kitsou, Georgios D Ayiomamitis, Apostolos Zaravinos.
Int J Oncol, 2020 May 30; 57(1). PMID: 32468013    Free PMC article.
Tumor Mutational Burden and PTEN Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer.
Romualdo Barroso-Sousa, Tanya E Keenan, +18 authors, Sara M Tolaney.
Clin Cancer Res, 2020 Feb 06; 26(11). PMID: 32019858    Free PMC article.
Inhibition of MICA and MICB Shedding Elicits NK-Cell-Mediated Immunity against Tumors Resistant to Cytotoxic T Cells.
Lucas Ferrari de Andrade, Sushil Kumar, +6 authors, Kai W Wucherpfennig.
Cancer Immunol Res, 2020 Mar 27; 8(6). PMID: 32209637    Free PMC article.
Personalized neoantigen vaccination with synthetic long peptides: recent advances and future perspectives.
Xiaotong Chen, Ju Yang, Lifeng Wang, Baorui Liu.
Theranostics, 2020 Jun 03; 10(13). PMID: 32483434    Free PMC article.
Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice.
Simone Ragusa, Borja Prat-Luri, +17 authors, Tatiana V Petrova.
J Clin Invest, 2020 Feb 06; 130(3). PMID: 32015230    Free PMC article.
Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.
Marcus Ruscetti, John P Morris, +17 authors, Scott W Lowe.
Cell, 2020 Apr 03; 181(2). PMID: 32234521    Free PMC article.
The impact of immunotherapy on the survival of pancreatic adenocarcinoma patients who received definitive surgery of the pancreatic tumor: a retrospective analysis of the National Cancer Database.
Saber Amin, Michael Baine, +2 authors, Chi Lin.
Radiat Oncol, 2020 Jun 05; 15(1). PMID: 32493354    Free PMC article.
Over-Expression and Prognostic Significance of HHLA2, a New Immune Checkpoint Molecule, in Human Clear Cell Renal Cell Carcinoma.
Zhen Zhang, Jinyan Liu, +7 authors, Yi Zhang.
Front Cell Dev Biol, 2020 Jun 09; 8. PMID: 32509772    Free PMC article.
Engineering bionic T cells: signal 1, signal 2, signal 3, reprogramming and the removal of inhibitory mechanisms.
Iñaki Etxeberria, Irene Olivera, +4 authors, Ignacio Melero.
Cell Mol Immunol, 2020 May 21; 17(6). PMID: 32433539    Free PMC article.
HLA class-I and class-II restricted neoantigen loads predict overall survival in breast cancer.
Yingxue Ren, Yesesri Cherukuri, +9 authors, Yan W Asmann.
Oncoimmunology, 2020 Jun 12; 9(1). PMID: 32523802    Free PMC article.
Recent Advances: The Imbalance of Immune Cells and Cytokines in the Pathogenesis of Hepatocellular Carcinoma.
Kumar Jayant, Nagy Habib, +2 authors, Ramesh Arasaradnam.
Diagnostics (Basel), 2020 May 30; 10(5). PMID: 32466214    Free PMC article.
Precision Stereotactic Radiotherapy for Spinal Tumors: Mechanism, Efficacy, and Issues.
Hongqing Zhuang, Hongxia Zhuang, Ning Lang, Jiandong Liu.
Front Oncol, 2020 Jun 13; 10. PMID: 32528894    Free PMC article.
Immunotherapy in colorectal cancer: rationale, challenges and potential.
Karuna Ganesh, Zsofia K Stadler, +4 authors, Luis A Diaz.
Nat Rev Gastroenterol Hepatol, 2019 Mar 20; 16(6). PMID: 30886395    Free PMC article.
Highly Cited. Review.
Body composition is prognostic and predictive of ipilimumab activity in metastatic melanoma.
Michael P Chu, Yuetong Li, +4 authors, Michael B Sawyer.
J Cachexia Sarcopenia Muscle, 2020 Feb 14; 11(3). PMID: 32053287    Free PMC article.
Adjuvant Effect of Toll-Like Receptor 9 Activation on Cancer Immunotherapy Using Checkpoint Blockade.
Yu-Chen Chuang, Jen-Chih Tseng, +3 authors, Tsung-Hsien Chuang.
Front Immunol, 2020 Jun 18; 11. PMID: 32547560    Free PMC article.
Immune Evasion by Head and Neck Cancer: Foundations for Combination Therapy.
Joshua D Horton, Hannah M Knochelmann, +2 authors, David M Neskey.
Trends Cancer, 2019 Apr 10; 5(4). PMID: 30961829    Free PMC article.
Limited MOMP, ATM, and their roles in carcinogenesis and cancer treatment.
Xuhui Bao, Xinjian Liu, Fang Li, Chuan-Yuan Li.
Cell Biosci, 2020 Jun 23; 10. PMID: 32566127    Free PMC article.
Transimmunization restores immune surveillance and prevents recurrence in a syngeneic mouse model of ovarian cancer.
Ayesha B Alvero, Douglas Hanlon, +9 authors, Gil Mor.
Oncoimmunology, 2020 Jun 23; 9(1). PMID: 32566387    Free PMC article.
Prognostic value of tumor mutation burden (TMB) and INDEL burden (IDB) in cancer: current view and clinical applications.
Anwaar Saeed, Mohamed E Salem.
Ann Transl Med, 2020 Jun 23; 8(9). PMID: 32566602    Free PMC article.
Towards new horizons: characterization, classification and implications of the tumour antigenic repertoire.
Sebastian P Haen, Markus W Löffler, Hans-Georg Rammensee, Peter Brossart.
Nat Rev Clin Oncol, 2020 Jun 24; 17(10). PMID: 32572208    Free PMC article.
The Cancer-Immune Set Point in Oesophageal Cancer.
Robert Power, Maeve A Lowery, John V Reynolds, Margaret R Dunne.
Front Oncol, 2020 Jun 26; 10. PMID: 32582553    Free PMC article.
Biological Factors behind Melanoma Response to Immune Checkpoint Inhibitors.
Magdalena Olbryt, Marcin Rajczykowski, Wiesława Widłak.
Int J Mol Sci, 2020 Jun 11; 21(11). PMID: 32517213    Free PMC article.
Real-world treatment efficacy of anti-programmed death-1 combined with anti-angiogenesis therapy in non-small cell lung cancer patients.
Lupeng Qiu, Xiao Zhao, +7 authors, Shunchang Jiao.
Medicine (Baltimore), 2020 Jun 17; 99(24). PMID: 32541476    Free PMC article.
Brain immunology and immunotherapy in brain tumours.
John H Sampson, Michael D Gunn, Peter E Fecci, David M Ashley.
Nat Rev Cancer, 2019 Dec 07; 20(1). PMID: 31806885    Free PMC article.
Cancer Epigenetics, Tumor Immunity, and Immunotherapy.
Jian Cao, Qin Yan.
Trends Cancer, 2020 Jul 02; 6(7). PMID: 32610068    Free PMC article.
The impact of immunotherapy on the survival of pancreatic adenocarcinoma patients who do not receive definitive surgery of the tumor.
Saber Amin, Michael Baine, +2 authors, Chi Lin.
Clin Transl Radiat Oncol, 2020 Jul 03; 24. PMID: 32613090    Free PMC article.
USMPep: universal sequence models for major histocompatibility complex binding affinity prediction.
Johanna Vielhaben, Markus Wenzel, Wojciech Samek, Nils Strodthoff.
BMC Bioinformatics, 2020 Jul 04; 21(1). PMID: 32615972    Free PMC article.
Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients.
Nicolas Gonzalo Núñez, Jimena Tosello Boari, +18 authors, Eliane Piaggio.
Nat Commun, 2020 Jul 01; 11(1). PMID: 32601304    Free PMC article.
Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer.
Daniel J McGrail, Jeannine Garnett, +20 authors, Shiaw-Yih Lin.
Cancer Cell, 2020 Feb 29; 37(3). PMID: 32109374    Free PMC article.
Mechanistic insight of predictive biomarkers for antitumor PD‑1/PD‑L1 blockade: A paradigm shift towards immunome evaluation (Review).
Wenjie You, Bin Shang, +3 authors, Shujuan Jiang.
Oncol Rep, 2020 Jul 07; 44(2). PMID: 32627031    Free PMC article.
PD-L1 Expression Affects Neoantigen Presentation.
Masahiro Okada, Kanako Shimizu, +6 authors, Shin-Ichiro Fujii.
iScience, 2020 Jul 08; 23(6). PMID: 32629606    Free PMC article.
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
Andrea Cossarizza, Hyun-Dong Chang, +433 authors, Arturo Zychlinsky.
Eur J Immunol, 2019 Oct 22; 49(10). PMID: 31633216    Free PMC article.
Highly Cited.
Analysis of tumor mutational burden: correlation of five large gene panels with whole exome sequencing.
Carina Heydt, Jan Rehker, +8 authors, Sabine Merkelbach-Bruse.
Sci Rep, 2020 Jul 11; 10(1). PMID: 32647293    Free PMC article.
Study protocol for an open-label, single-arm, phase Ib/II study of combination of toripalimab, nab-paclitaxel, and gemcitabine as the first-line treatment for patients with unresectable pancreatic ductal adenocarcinoma.
Lin Shui, Ke Cheng, +5 authors, Dan Cao.
BMC Cancer, 2020 Jul 11; 20(1). PMID: 32646394    Free PMC article.
Simulated ablation for detection of cells impacting paracrine signalling in histology analysis.
Jake P Taylor-King, Etienne Baratchart, +6 authors, Andriy Marusyk.
Math Med Biol, 2018 Feb 17; 36(1). PMID: 29452382    Free PMC article.
Overcoming immunotherapeutic resistance by targeting the cancer inflammation cycle.
Max M Wattenberg, Gregory L Beatty.
Semin Cancer Biol, 2020 Jan 19; 65. PMID: 31954172    Free PMC article.
Challenges and strategies for next-generation bispecific antibody-based antitumor therapeutics.
Heliang Li, Phei Er Saw, Erwei Song.
Cell Mol Immunol, 2020 Apr 22; 17(5). PMID: 32313210    Free PMC article.
ImmunoPET in Multiple Myeloma-What? So What? Now What?
Clément Bailly, Benjamin Chalopin, +8 authors, Michel Chérel.
Cancers (Basel), 2020 Jun 10; 12(6). PMID: 32512883    Free PMC article.
Combined PARP Inhibition and Immune Checkpoint Therapy in Solid Tumors.
Florent Peyraud, Antoine Italiano.
Cancers (Basel), 2020 Jun 13; 12(6). PMID: 32526888    Free PMC article.
Engineering Strategies to Enhance TCR-Based Adoptive T Cell Therapy.
Jan A Rath, Caroline Arber.
Cells, 2020 Jun 24; 9(6). PMID: 32570906    Free PMC article.
Molecular Interplay between Dormant Bone Marrow-Resident Cells (BMRCs) and CTCs in Breast Cancer.
Debasish Boral, Haowen N Liu, S Ray Kenney, Dario Marchetti.
Cancers (Basel), 2020 Jun 25; 12(6). PMID: 32575420    Free PMC article.
Uncovering the Tumor Antigen Landscape: What to Know about the Discovery Process.
Sara Feola, Jacopo Chiaro, Beatriz Martins, Vincenzo Cerullo.
Cancers (Basel), 2020 Jun 27; 12(6). PMID: 32585818    Free PMC article.
Integration of Tumor Mutation Burden and PD-L1 Testing in Routine Laboratory Diagnostics in Non-Small Cell Lung Cancer.
Stefanie Schatz, Markus Falk, +12 authors, Lukas C Heukamp.
Cancers (Basel), 2020 Jul 01; 12(6). PMID: 32599951    Free PMC article.
Cancer systems immunology.
Nathan E Reticker-Flynn, Edgar G Engleman.
Elife, 2020 Jul 14; 9. PMID: 32657757    Free PMC article.
Tumor mutation burden associated with miRNA-gene interaction outcome mediates the survival of patients with liver hepatocellular carcinoma.
Qing-Jiang Yu, Yi-Zhi Liang, Xiao-Ping Mei, Tai-Yong Fang.
EXCLI J, 2020 Jul 16; 19. PMID: 32665773    Free PMC article.
The Connection Between Minor H Antigens and Neoantigens and the Missing Link in Their Prediction.
Tuna Mutis, Anastasia Xagara, Robbert M Spaapen.
Front Immunol, 2020 Jul 17; 11. PMID: 32670277    Free PMC article.
Nucleophosmin 1 Mutations in Acute Myeloid Leukemia.
Jabra Zarka, Nicholas J Short, Rashmi Kanagal-Shamanna, Ghayas C Issa.
Genes (Basel), 2020 Jun 18; 11(6). PMID: 32545659    Free PMC article.
Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma.
Meenakshi Hegde, Sujith K Joseph, +22 authors, Nabil Ahmed.
Nat Commun, 2020 Jul 17; 11(1). PMID: 32669548    Free PMC article.
Heterogeneity of Glucose Transport in Lung Cancer.
Cesar A Martinez, Claudio Scafoglio.
Biomolecules, 2020 Jun 11; 10(6). PMID: 32517099    Free PMC article.
Immunization associated with primary tumor growth leads to rejection of commonly used syngeneic tumors upon tumor rechallenge.
Bruno Alicke, Klara Totpal, +5 authors, Stephen E Gould.
J Immunother Cancer, 2020 Jul 18; 8(2). PMID: 32675310    Free PMC article.
Establishment of the prognostic index of lung squamous cell carcinoma based on immunogenomic landscape analysis.
Jianguo Zhang, Jianzhong Zhang, +9 authors, Conghua Xie.
Cancer Cell Int, 2020 Jul 24; 20. PMID: 32699529    Free PMC article.
Deleting key autophagy elongation proteins induces acquirement of tumor-associated phenotypes via ISG15.
EunBin Kong, Hag Dong Kim, Joon Kim.
Cell Death Differ, 2020 Mar 05; 27(8). PMID: 32127658    Free PMC article.
Cancer immunotherapy using checkpoint blockade.
Antoni Ribas, Jedd D Wolchok.
Science, 2018 Mar 24; 359(6382). PMID: 29567705    Free PMC article.
Highly Cited. Review.
Cellular heterogeneity map of diverse immune and stromal phenotypes within breast tumor microenvironment.
Yuan Li, Zuhua Chen, +2 authors, Weiping Tao.
PeerJ, 2020 Jul 31; 8. PMID: 32728493    Free PMC article.
Recurrent Neoantigens in Colorectal Cancer as Potential Immunotherapy Targets.
Chao Chen, Songming Liu, Ruokai Qu, Bo Li.
Biomed Res Int, 2020 Aug 01; 2020. PMID: 32733937    Free PMC article.
Nanomedicine and Onco-Immunotherapy: From the Bench to Bedside to Biomarkers.
Vanessa Acebes-Fernández, Alicia Landeria-Viñuela, +5 authors, Manuel Fuentes.
Nanomaterials (Basel), 2020 Jul 03; 10(7). PMID: 32610601    Free PMC article.
The natural adaptive evolution of cancer: The metastatic ability of cancer cells.
Gheorghe-Emilian Olteanu, Ioana-Maria Mihai, +2 authors, Virgil Paunescu.
Bosn J Basic Med Sci, 2020 Feb 06; 20(3). PMID: 32020846    Free PMC article.
Efficacy of immunotherapy targeting the neoantigen derived from epidermal growth factor receptor T790M/C797S mutation in non-small cell lung cancer.
Yu Akazawa, Yuki Saito, +6 authors, Tetsuya Nakatsura.
Cancer Sci, 2020 May 12; 111(8). PMID: 32391625    Free PMC article.
Cancer Immune Therapy for Philadelphia Chromosome-Negative Chronic Myeloproliferative Neoplasms.
Morten Orebo Holmström, Hans Carl Hasselbalch, Mads Hald Andersen.
Cancers (Basel), 2020 Jul 08; 12(7). PMID: 32630667    Free PMC article.
Ferroptosis, necroptosis, and pyroptosis in anticancer immunity.
Rong Tang, Jin Xu, +6 authors, Si Shi.
J Hematol Oncol, 2020 Aug 12; 13(1). PMID: 32778143    Free PMC article.
Identification of Clonal Neoantigens Derived From Driver Mutations in an EGFR-Mutated Lung Cancer Patient Benefitting From Anti-PD-1.
Di Wu, Yangyang Liu, +12 authors, Li Liu.
Front Immunol, 2020 Aug 15; 11. PMID: 32793190    Free PMC article.
Resistance Mechanisms of Anti-PD1/PDL1 Therapy in Solid Tumors.
Qingyang Lei, Dan Wang, +2 authors, Yi Zhang.
Front Cell Dev Biol, 2020 Aug 15; 8. PMID: 32793604    Free PMC article.
The T cell differentiation landscape is shaped by tumour mutations in lung cancer.
Ehsan Ghorani, James L Reading, +49 authors, Sergio A Quezada.
Nat Cancer, 2020 Aug 18; 1(5). PMID: 32803172    Free PMC article.
CRISPR and transposon in vivo screens for cancer drivers and therapeutic targets.
Imran Noorani, Allan Bradley, Jorge de la Rosa.
Genome Biol, 2020 Aug 20; 21(1). PMID: 32811551    Free PMC article.
Synthetic High-density Lipoprotein Nanodiscs for Personalized Immunotherapy Against Gliomas.
Lindsay Scheetz, Padma Kadiyala, +7 authors, James J Moon.
Clin Cancer Res, 2020 May 23; 26(16). PMID: 32439701    Free PMC article.
Sequential PDT and PTT Using Dual-Modal Single-Walled Carbon Nanohorns Synergistically Promote Systemic Immune Responses against Tumor Metastasis and Relapse.
Jingxing Yang, Mengfei Hou, +10 authors, Chunfu Zhang.
Adv Sci (Weinh), 2020 Aug 25; 7(16). PMID: 32832363    Free PMC article.
Pembrolizumab in the treatment of locally advanced or metastatic urothelial carcinoma: clinical trial evidence and experience.
Michael Crist, Gopa Iyer, +2 authors, Arjun V Balar.
Ther Adv Urol, 2019 May 07; 11. PMID: 31057668    Free PMC article.
CD8+ T cell states in human cancer: insights from single-cell analysis.
Anne M van der Leun, Daniela S Thommen, Ton N Schumacher.
Nat Rev Cancer, 2020 Feb 07; 20(4). PMID: 32024970    Free PMC article.
Harnessing the Complete Repertoire of Conventional Dendritic Cell Functions for Cancer Immunotherapy.
Lukas Amon, Lukas Hatscher, +2 authors, Christian H K Lehmann.
Pharmaceutics, 2020 Jul 18; 12(7). PMID: 32674488    Free PMC article.
"To Anticipate": Neoadjuvant Therapy in Melanoma with a Focus on Predictive Biomarkers.
Mattia Garutti, Silvia Buriolla, +5 authors, Fabio Puglisi.
Cancers (Basel), 2020 Jul 28; 12(7). PMID: 32708968    Free PMC article.
Leveraging Public Single-Cell and Bulk Transcriptomic Datasets to Delineate MAIT Cell Roles and Phenotypic Characteristics in Human Malignancies.
Tony Yao, Parisa Shooshtari, S M Mansour Haeryfar.
Front Immunol, 2020 Aug 28; 11. PMID: 32849590    Free PMC article.
A Greedy Algorithm-Based Stem Cell LncRNA Signature Identifies a Novel Subgroup of Lung Adenocarcinoma Patients With Poor Prognosis.
Seema Khadirnaikar, Annesha Chatterjee, Pranjal Kumar, Sudhanshu Shukla.
Front Oncol, 2020 Aug 28; 10. PMID: 32850350    Free PMC article.
Mechanisms of Cancer Resistance to Immunotherapy.
Rilan Bai, Naifei Chen, +5 authors, Jiuwei Cui.
Front Oncol, 2020 Aug 28; 10. PMID: 32850400    Free PMC article.