Immunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop

Roch Houot ¹, Philippe Gaulard ², Robert Schreiber ³, Ira Mellman ⁴, Olivier Lambotte ⁵, Pierre G Coulie ⁶, Thierry Fest ⁷, Alan Korman ⁸, Ronald Levy ⁹, Margaret Shipp ¹⁰, Karin Tarte ⁷, Holbrook Kohrt ¹¹, Aurélien Marabelle ¹², Stephen Ansell ¹³, Hervé Watier ¹⁴, Andrea van Elsas ¹⁵, Arun Balakumaran ¹⁶, Frederick Arce Vargas ¹⁷, Sergio A Quezada ¹⁷, Gilles Salles ¹⁸, Daniel Olive ¹⁹

Affiliations

¹ Department of Hematology, CHU de Rennes , Rennes, France.
² Department of Pathology, Inserm U955, Université Paris-Est, CHU Henri Mondor , Créteil, France.
³ Department of Pathology and Immunology, Washington University , St. Louis, MO, USA.
⁴ Genentech , South San Francisco, CA, USA.
⁵ Department of Clinical Immunology and Internal Medicine, Hospital Kremlin Bicêtre, Université Paris-Sud , Orsay, France.
⁶ de Duve Institute, Université Catholique de Louvain , Brussels, Belgium.
⁷ Inserm U917, CHU de Rennes , Rennes, France.
⁸ Bristol-Myers Squibb , CA, USA.
⁹ Stanford School of Medicine , Stanford, CA, USA.
¹⁰ Dana-Farber Cancer Institute , Boston, MA, USA.
¹¹ Department of Medicine, Stanford School of Medicine , Stanford, CA, USA.
¹² Gustave Roussy Cancer Campus , Villejuif, France.
¹³ Division of Hematology , Mayo Clinic, Rochester, MN, USA.
¹⁴ CHRU de Tours, Université François-Rabelais and CNRS, UMR7292 , Tours, France.
¹⁵ Aduro Biotech Europe , Oss, The Netherlands.
¹⁶ Clinical Research-Oncology , Merck & Co , Kenilworth, NJ, USA.
¹⁷ UCL Cancer Institute, University College of London , London, UK.
¹⁸ Department of Hematology, Université Claude Bernard, Hospices Civils de Lyon , INSERM 1052 , Lyon, France.
¹⁹ Inserm UMR 1068, Institut Paoli Calmettes, Aix Marseille Université , Marseille, France.

PMID: 27622041
74 References
2 citations

Abstract

In November 2015, the CALYM Carnot Institute held a 2-d workshop to discuss the current and future development of immunomodulatory antibodies for the treatment of lymphoma. Highlights from the workshop are presented in this article.

Keywords: Immunomodulation; immunotherapy; lymphoma; programmed cell death 1 ligand 1; programmed cell death 1 receptor.

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