. 2019 Jan; 18(3):175-196.
doi: 10.1038/s41573-018-0006-z.

Delivery technologies for cancer immunotherapy

Rachel S Riley 1 Carl H June 2 Robert Langer 3 Michael J Mitchell 4 
  • PMID: 30622344
  •     238 References
  •     346 citations


Immunotherapy has become a powerful clinical strategy for treating cancer. The number of immunotherapy drug approvals has been increasing, with numerous treatments in clinical and preclinical development. However, a key challenge in the broad implementation of immunotherapies for cancer remains the controlled modulation of the immune system, as these therapeutics have serious adverse effects including autoimmunity and nonspecific inflammation. Understanding how to increase the response rates to various classes of immunotherapy is key to improving efficacy and controlling these adverse effects. Advanced biomaterials and drug delivery systems, such as nanoparticles and the use of T cells to deliver therapies, could effectively harness immunotherapies and improve their potency while reducing toxic side effects. Here, we discuss these research advances, as well as the opportunities and challenges for integrating delivery technologies into cancer immunotherapy, and we critically analyse the outlook for these emerging areas.

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Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles.
Matthias T Stephan, Sirkka B Stephan, +2 authors, Darrell J Irvine.
Biomaterials, 2012 May 19; 33(23). PMID: 22594972    Free PMC article.
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Jennifer Couzin-Frankel.
Science, 2013 Dec 21; 342(6165). PMID: 24357284
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Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma.
Hao Liu, Kamila Naxerova, +22 authors, Rakesh K Jain.
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Integrating Next-Generation Dendritic Cell Vaccines into the Current Cancer Immunotherapy Landscape.
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Trends Immunol, 2017 Jun 15; 38(8). PMID: 28610825
Highly Cited. Review.
Engineered T cells: the promise and challenges of cancer immunotherapy.
Andrew D Fesnak, Carl H June, Bruce L Levine.
Nat Rev Cancer, 2016 Aug 24; 16(9). PMID: 27550819    Free PMC article.
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The immunobiology of CD27 and OX40 and their potential as targets for cancer immunotherapy.
Sarah L Buchan, Anne Rogel, Aymen Al-Shamkhani.
Blood, 2017 Nov 10; 131(1). PMID: 29118006
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Sipuleucel-T in the treatment of prostate cancer: an evidence-based review of its place in therapy.
Julie N Graff, Erin D Chamberlain.
Core Evid, 2015 Jan 08; 10. PMID: 25565923    Free PMC article.
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J R Quesada, E M Hersh, +5 authors, J U Gutterman.
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Omar A Ali, Catia Verbeke, +6 authors, David J Mooney.
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G I Kirchner, A Franzke, +9 authors, J Atzpodien.
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Phase Ib Study of Utomilumab (PF-05082566), a 4-1BB/CD137 Agonist, in Combination with Pembrolizumab (MK-3475) in Patients with Advanced Solid Tumors.
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PD-1 and PD-L1 Checkpoint Signaling Inhibition for Cancer Immunotherapy: Mechanism, Combinations, and Clinical Outcome.
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Therapeutic cancer vaccines: past, present, and future.
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The Principles of Engineering Immune Cells to Treat Cancer.
Wendell A Lim, Carl H June.
Cell, 2017 Feb 12; 168(4). PMID: 28187291    Free PMC article.
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T Keler, L He, V Ramakrishna, B Champion.
Oncogene, 2007 May 29; 26(25). PMID: 17530028
A facile approach to enhance antigen response for personalized cancer vaccination.
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Nat Mater, 2018 Mar 07; 17(6). PMID: 29507416    Free PMC article.
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Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery.
Jicheng Yu, Yuqi Zhang, +6 authors, Zhen Gu.
Proc Natl Acad Sci U S A, 2015 Jun 24; 112(27). PMID: 26100900    Free PMC article.
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Hao Yin, Rosemary L Kanasty, +3 authors, Daniel G Anderson.
Nat Rev Genet, 2014 Jul 16; 15(8). PMID: 25022906
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L Li, S P Goedegebuure, W E Gillanders.
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Nat Rev Drug Discov, 2016 Sep 30; 15(10). PMID: 27681782
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J Control Release, 2016 Jan 01; 240. PMID: 26718856
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Preclinical mouse cancer models: a maze of opportunities and challenges.
Chi-Ping Day, Glenn Merlino, Terry Van Dyke.
Cell, 2015 Sep 26; 163(1). PMID: 26406370    Free PMC article.
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Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma.
Avery D Posey, Robert D Schwab, +19 authors, Carl H June.
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Omar A Ali, Prakriti Tayalia, +2 authors, David J Mooney.
Adv Funct Mater, 2014 Apr 02; 23(36). PMID: 24688455    Free PMC article.
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Cell Mol Immunol, 2007 May 09; 4(2). PMID: 17484804
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Pål Johansen, Deepa Mohanan, +2 authors, Bruno Gander.
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Yanqi Ye, Jinqiang Wang, +4 authors, Zhen Gu.
ACS Nano, 2016 Sep 07; 10(9). PMID: 27599066
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Type I Interferons and Natural Killer Cell Regulation in Cancer.
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Front Immunol, 2017 Apr 15; 8. PMID: 28408907    Free PMC article.
A Light Responsive Nanoparticle-Based Delivery System Using Pheophorbide A Graft Polyethylenimine for Dendritic Cell-Based Cancer Immunotherapy.
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Mol Pharm, 2017 Mar 16; 14(5). PMID: 28296410
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Genome-Editing Technologies in Adoptive T Cell Immunotherapy for Cancer.
Nathan Singh, Junwei Shi, Carl H June, Marco Ruella.
Curr Hematol Malig Rep, 2017 Oct 19; 12(6). PMID: 29039115    Free PMC article.
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Omar A Ali, Nathaniel Huebsch, +2 authors, David J Mooney.
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mRNA vaccines - a new era in vaccinology.
Norbert Pardi, Michael J Hogan, Frederick W Porter, Drew Weissman.
Nat Rev Drug Discov, 2018 Jan 13; 17(4). PMID: 29326426    Free PMC article.
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Alberto Mantovani, Paola Allavena, Antonio Sica, Frances Balkwill.
Nature, 2008 Jul 25; 454(7203). PMID: 18650914
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Abhishek Vartak, Steven J Sucheck.
Vaccines (Basel), 2016 Apr 23; 4(2). PMID: 27104575    Free PMC article.
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Is autoimmunity the Achilles' heel of cancer immunotherapy?
Carl H June, Jeremy T Warshauer, Jeffrey A Bluestone.
Nat Med, 2017 May 06; 23(5). PMID: 28475571
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Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas.
Stephen J Schuster, Jakub Svoboda, +13 authors, Carl H June.
N Engl J Med, 2017 Dec 12; 377(26). PMID: 29226764    Free PMC article.
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RNA-Based Vaccines in Cancer Immunotherapy.
Megan A McNamara, Smita K Nair, Eda K Holl.
J Immunol Res, 2015 Dec 15; 2015. PMID: 26665011    Free PMC article.
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Clin Cancer Res, 2013 Oct 08; 20(1). PMID: 24097874    Free PMC article.
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Delivering safer immunotherapies for cancer.
Lauren Milling, Yuan Zhang, Darrell J Irvine.
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Polymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo.
Antonella Mangraviti, Stephany Yi Tzeng, +15 authors, Jordan J Green.
ACS Nano, 2015 Feb 03; 9(2). PMID: 25643235    Free PMC article.
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David M Barrett, Nathan Singh, +2 authors, Carl H June.
Annu Rev Med, 2013 Nov 28; 65. PMID: 24274181    Free PMC article.
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Biomaterials, 2013 Dec 19; 35(8). PMID: 24345735    Free PMC article.
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Michael J Mitchell, Christina S Chen, +2 authors, Michael R King.
J Control Release, 2012 Mar 17; 160(3). PMID: 22421423    Free PMC article.
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Cancer nanomedicine: from targeted delivery to combination therapy.
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Trends Mol Med, 2015 Feb 07; 21(4). PMID: 25656384    Free PMC article.
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James I Andorko, Krystina L Hess, Kevin G Pineault, Christopher M Jewell.
Acta Biomater, 2015 Dec 29; 32. PMID: 26708710    Free PMC article.
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Highly Cited.
T cell exclusion, immune privilege, and the tumor microenvironment.
Johanna A Joyce, Douglas T Fearon.
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Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia.
David L Porter, Wei-Ting Hwang, +15 authors, Carl H June.
Sci Transl Med, 2015 Sep 04; 7(303). PMID: 26333935    Free PMC article.
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Immunization with cocktail of HIV-derived peptides in montanide ISA-51 is immunogenic, but causes sterile abscesses and unacceptable reactogenicity.
Barney S Graham, M Juliana McElrath, +14 authors, AIDS Vaccine Evaluation Group.
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Sylvia Lee, Kim Margolin.
Cancers (Basel), 2011 Jan 01; 3(4). PMID: 24213115    Free PMC article.
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The role of IL-10 in human B cell activation, proliferation, and differentiation.
K Itoh, S Hirohata.
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The efficacy of intracranial PLG-based vaccines is dependent on direct implantation into brain tissue.
Omar A Ali, Edward Doherty, +5 authors, Dwaine F Emerich.
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Expert Rev Clin Pharmacol, 2011 Jun 07; 4(2). PMID: 21643519    Free PMC article.
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma.
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Ton N Schumacher, Robert D Schreiber.
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Charles Schmidt.
Nature, 2018 Jan 03; 552(7685). PMID: 29293245
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Tyler R Simpson, Fubin Li, +11 authors, Sergio A Quezada.
J Exp Med, 2013 Jul 31; 210(9). PMID: 23897981    Free PMC article.
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Curr Opin Immunol, 2015 Nov 27; 39. PMID: 26609943    Free PMC article.
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Shahid Ahmed, Kanti R Rai.
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DNA vaccines: an historical perspective and view to the future.
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Drew M Pardoll.
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Sipuleucel-T immunotherapy for castration-resistant prostate cancer.
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Inhibition of tumor angiogenesis by interferon-γ by suppression of tumor-associated macrophage differentiation.
Tao Sun, Ye Yang, +4 authors, Chunlin Ge.
Oncol Res, 2014 May 24; 21(5). PMID: 24854099
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Recent progress in GM-CSF-based cancer immunotherapy.
Wan-Lun Yan, Kuan-Yin Shen, +2 authors, Shih-Jen Liu.
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Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18.
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Highly Cited.
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Current Trends and Challenges in the Clinical Translation of Nanoparticulate Nanomedicines: Pathways for Translational Development and Commercialization.
Susan Hua, Maria B C de Matos, Josbert M Metselaar, Gert Storm.
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Highly Cited. Review.
Cancer immunotherapy using checkpoint blockade.
Antoni Ribas, Jedd D Wolchok.
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Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
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A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer.
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Highly Cited.
Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating miRNAs Inhibit Glioblastoma Growth and Prolong Survival.
Hernando Lopez-Bertoni, Kristen L Kozielski, +7 authors, Jordan J Green.
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CD19-Targeted CAR T cells as novel cancer immunotherapy for relapsed or refractory B-cell acute lymphoblastic leukemia.
Marco L Davila, Renier J Brentjens.
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Whole Tumor Antigen Vaccines: Where Are We?
Cheryl Lai-Lai Chiang, George Coukos, Lana E Kandalaft.
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Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology.
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Adv Drug Deliv Rev, 2013 Nov 26; 66. PMID: 24270007    Free PMC article.
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Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.
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Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs.
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64Cu-MM-302 Positron Emission Tomography Quantifies Variability of Enhanced Permeability and Retention of Nanoparticles in Relation to Treatment Response in Patients with Metastatic Breast Cancer.
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Clin Cancer Res, 2017 Mar 17; 23(15). PMID: 28298546    Free PMC article.
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Anti-tumor Activity of Toll-Like Receptor 7 Agonists.
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Front Pharmacol, 2017 Jun 18; 8. PMID: 28620298    Free PMC article.
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Application of PD-1 Blockade in Cancer Immunotherapy.
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Novel Delivery Systems for Checkpoint Inhibitors.
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Medicines (Basel), 2019 Aug 03; 6(3). PMID: 31373327    Free PMC article.
Interactions of Nanoparticles and Biosystems: Microenvironment of Nanoparticles and Biomolecules in Nanomedicine.
Carlota Auría-Soro, Tabata Nesma, +7 authors, Manuel Fuentes.
Nanomaterials (Basel), 2019 Sep 27; 9(10). PMID: 31554176    Free PMC article.
The Evolving Landscape of Biomarkers for Anti-PD-1 or Anti-PD-L1 Therapy.
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J Clin Med, 2019 Sep 29; 8(10). PMID: 31557787    Free PMC article.
Emergent Nanotechnological Strategies for Systemic Chemotherapy against Melanoma.
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Nanomaterials (Basel), 2019 Oct 17; 9(10). PMID: 31614947    Free PMC article.
Emerging modes-of-action in drug discovery.
Eric Valeur, Frank Narjes, Christian Ottmann, Alleyn T Plowright.
Medchemcomm, 2019 Nov 02; 10(9). PMID: 31673315    Free PMC article.
Red blood cell-derived nanoerythrosome for antigen delivery with enhanced cancer immunotherapy.
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Sci Adv, 2019 Nov 05; 5(10). PMID: 31681841    Free PMC article.
Recent advances and challenges of repurposing nanoparticle-based drug delivery systems to enhance cancer immunotherapy.
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Theranostics, 2019 Nov 07; 9(25). PMID: 31695807    Free PMC article.
Advances in Engineering Cells for Cancer Immunotherapy.
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J Nanobiotechnology, 2019 Nov 09; 17(1). PMID: 31699100    Free PMC article.
Engineering Nanoparticles to Reprogram the Tumor Immune Microenvironment for Improved Cancer Immunotherapy.
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Theranostics, 2019 Nov 23; 9(26). PMID: 31754376    Free PMC article.
Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy.
John-Michael Williford, Jun Ishihara, +6 authors, Jeffrey A Hubbell.
Sci Adv, 2019 Dec 18; 5(12). PMID: 31844672    Free PMC article.
Overview of Immune Checkpoint Inhibitors Therapy for Hepatocellular Carcinoma, and The ITA.LI.CA Cohort Derived Estimate of Amenability Rate to Immune Checkpoint Inhibitors in Clinical Practice.
Edoardo G Giannini, Andrea Aglitti, +15 authors, Associazione Italiana per lo Studio del Fegato (AISF) HCC Special Interest Group.
Cancers (Basel), 2019 Nov 02; 11(11). PMID: 31671581    Free PMC article.
Decellularized Lymph Node Scaffolding as a Carrier for Dendritic Cells to Induce Anti-Tumor Immunity.
Hung-Jun Lin, Weu Wang, +4 authors, Der-Zen Liu.
Pharmaceutics, 2019 Nov 14; 11(11). PMID: 31717826    Free PMC article.
Nanoparticles versus Dendritic Cells as Vehicles to Deliver mRNA Encoding Multiple Epitopes for Immunotherapy.
Rebuma Firdessa-Fite, Rémi J Creusot.
Mol Ther Methods Clin Dev, 2019 Dec 25; 16. PMID: 31871957    Free PMC article.
Polymeric Nanocarrier Formulations of Biologics Using Inverse Flash NanoPrecipitation.
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The potential mechanism, recognition and clinical significance of tumor pseudoprogression after immunotherapy.
Wenxiao Jia, Qianqian Gao, +2 authors, Jinming Yu.
Cancer Biol Med, 2020 Jan 08; 16(4). PMID: 31908886    Free PMC article.
The Genomic Landscape of Antigenic Targets for T Cell-Based Leukemia Immunotherapy.
Marie-Pierre Hardy, Krystel Vincent, Claude Perreault.
Front Immunol, 2020 Jan 11; 10. PMID: 31921187    Free PMC article.
Peptide-based targeting of immunosuppressive cells in cancer.
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Bioact Mater, 2020 Jan 21; 5(1). PMID: 31956738    Free PMC article.
Highly efficient and tumor-selective nanoparticles for dual-targeted immunogene therapy against cancer.
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Sci Adv, 2020 Jan 31; 6(3). PMID: 31998834    Free PMC article.
Exploiting Current Understanding of Hypoxia Mediated Tumour Progression for Nanotherapeutic Development.
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Sequential MR Image-Guided Local Immune Checkpoint Blockade Cancer Immunotherapy Using Ferumoxytol Capped Ultralarge Pore Mesoporous Silica Carriers after Standard Chemotherapy.
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Dual pH-sensitive nanodrug blocks PD-1 immune checkpoint and uses T cells to deliver NF-κB inhibitor for antitumor immunotherapy.
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Cell Membrane-Camouflaged Nanocarriers for Cancer Diagnostic and Therapeutic.
Shengxian Li, Jianhua Liu, +3 authors, Yinghao Sun.
Front Pharmacol, 2020 Mar 03; 11. PMID: 32116701    Free PMC article.
T Cell Dysfunction and Exhaustion in Cancer.
Zhen Zhang, Shasha Liu, +3 authors, Yi Zhang.
Front Cell Dev Biol, 2020 Mar 03; 8. PMID: 32117960    Free PMC article.
Integrating nanomedicine into clinical radiotherapy regimens.
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Engineered Nanodelivery Systems to Improve DNA Vaccine Technologies.
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Front Immunol, 2020 Mar 21; 11. PMID: 32194568    Free PMC article.
Recent advances in tumor associated carbohydrate antigen based chimeric antigen receptor T cells and bispecific antibodies for anti-cancer immunotherapy.
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Semin Immunol, 2020 Jan 27; 47. PMID: 31982247    Free PMC article.
Nanoparticles for nucleic acid delivery: Applications in cancer immunotherapy.
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Near-infrared responsive 5-fluorouracil and indocyanine green loaded MPEG-PCL nanoparticle integrated with dissolvable microneedle for skin cancer therapy.
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Bioact Mater, 2020 Apr 30; 5(3). PMID: 32346657    Free PMC article.
Emerging Prospects for Nanoparticle-Enabled Cancer Immunotherapy.
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Smart cancer nanomedicine.
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Overcoming resistance to anti-PD1 and anti-PD-L1 treatment in gastrointestinal malignancies.
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Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics.
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Nat Commun, 2020 May 13; 11(1). PMID: 32393818    Free PMC article.
The solid progress of nanomedicine.
João Pedro Martins, José das Neves, +10 authors, Hélder A Santos.
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Green Tea Polyphenol EGCG Attenuates MDSCs-mediated Immunosuppression through Canonical and Non-Canonical Pathways in a 4T1 Murine Breast Cancer Model.
Ping Xu, Feng Yan, +4 authors, Le Ying.
Nutrients, 2020 Apr 16; 12(4). PMID: 32290071    Free PMC article.
A guide to cancer immunotherapy: from T cell basic science to clinical practice.
Alex D Waldman, Jill M Fritz, Michael J Lenardo.
Nat Rev Immunol, 2020 May 21; 20(11). PMID: 32433532    Free PMC article.
Messenger RNA delivery by hydrazone-activated polymers.
Marisa Juanes, Oliver Creese, Paco Fernández-Trillo, Javier Montenegro.
Medchemcomm, 2019 Aug 09; 10(7). PMID: 31391886    Free PMC article.
Adenovirus and Immunotherapy: Advancing Cancer Treatment by Combination.
Mizuho Sato-Dahlman, Christopher J LaRocca, Chikako Yanagiba, Masato Yamamoto.
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Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering.
Margaret M Billingsley, Nathan Singh, +3 authors, Michael J Mitchell.
Nano Lett, 2020 Jan 18; 20(3). PMID: 31951421    Free PMC article.
An approach using Caenorhabditis elegans screening novel targets to suppress tumour cell proliferation.
Yu-Qin Mao, San-Feng Han, +7 authors, Li-Shun Wang.
Cell Prolif, 2020 May 27; 53(6). PMID: 32452127    Free PMC article.
The Relevance of Transcription Factors in Gastric and Colorectal Cancer Stem Cells Identification and Eradication.
Diana Pádua, Paula Figueira, +2 authors, Patrícia Mesquita.
Front Cell Dev Biol, 2020 Jul 07; 8. PMID: 32626705    Free PMC article.
Arginine-Based Poly(I:C)-Loaded Nanocomplexes for the Polarization of Macrophages Toward M1-Antitumoral Effectors.
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Front Immunol, 2020 Aug 01; 11. PMID: 32733469    Free PMC article.
Editing of Endogenous Genes in Cellular Immunotherapies.
Theodore L Roth.
Curr Hematol Malig Rep, 2020 May 18; 15(4). PMID: 32415407    Free PMC article.
Nanomedicine and Onco-Immunotherapy: From the Bench to Bedside to Biomarkers.
Vanessa Acebes-Fernández, Alicia Landeria-Viñuela, +5 authors, Manuel Fuentes.
Nanomaterials (Basel), 2020 Jul 03; 10(7). PMID: 32610601    Free PMC article.
Proof-of-Concept of Electrical Activation of Liposome Nanocarriers: From Dry to Wet Experiments.
Laura Caramazza, Martina Nardoni, +4 authors, Stefania Petralito.
Front Bioeng Biotechnol, 2020 Aug 15; 8. PMID: 32793572    Free PMC article.
Intratumoral Immunotherapy for Early-stage Solid Tumors.
Wan Xing Hong, Sarah Haebe, +4 authors, Ronald Levy.
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Assessment of Cellular Uptake Efficiency According to Multiple Inhibitors of Fe3O4-Au Core-Shell Nanoparticles: Possibility to Control Specific Endocytosis in Colorectal Cancer Cells.
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Nanoscale Res Lett, 2020 Aug 18; 15(1). PMID: 32804261    Free PMC article.
Cancer Nanomedicine Special Issue Review Anticancer Drug Delivery with Nanoparticles: Extracellular Vesicles or Synthetic Nanobeads as Therapeutic Tools for Conventional Treatment or Immunotherapy.
Maria Raffaella Zocchi, Francesca Tosetti, Roberto Benelli, Alessandro Poggi.
Cancers (Basel), 2020 Jul 17; 12(7). PMID: 32668783    Free PMC article.
Biomaterial-Driven Immunomodulation: Cell Biology-Based Strategies to Mitigate Severe Inflammation and Sepsis.
Jackline Joy Martín Lasola, Henry Kamdem, Michael W McDaniel, Ryan M Pearson.
Front Immunol, 2020 Aug 28; 11. PMID: 32849612    Free PMC article.
Resistance to PD-1/PD-L1 blockade cancer immunotherapy: mechanisms, predictive factors, and future perspectives.
Jin-Yu Sun, Dengke Zhang, +4 authors, Jiansong Ji.
Biomark Res, 2020 Aug 31; 8. PMID: 32864132    Free PMC article.
Emerging Roles of 1D Vertical Nanostructures in Orchestrating Immune Cell Functions.
Yaping Chen, Ji Wang, +4 authors, Roey Elnathan.
Adv Mater, 2020 Aug 28; 32(40). PMID: 32844502    Free PMC article.
Advanced biomaterials for cancer immunotherapy.
Fan Yang, Kun Shi, +3 authors, Zhi-Yong Qian.
Acta Pharmacol Sin, 2020 Mar 04; 41(7). PMID: 32123302    Free PMC article.
Nanomedicine-based immunotherapy for central nervous system disorders.
Sumaira Hanif, Pir Muhammad, +4 authors, Bing-Yang Shi.
Acta Pharmacol Sin, 2020 May 30; 41(7). PMID: 32467570    Free PMC article.
Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy.
Jing Gao, Wei-Qi Wang, +2 authors, Hai-Jun Yu.
Acta Pharmacol Sin, 2020 Apr 23; 41(7). PMID: 32317755    Free PMC article.
Advances in synthetic lethality for cancer therapy: cellular mechanism and clinical translation.
Win Topatana, Sarun Juengpanich, +8 authors, Xiujun Cai.
J Hematol Oncol, 2020 Sep 05; 13(1). PMID: 32883316    Free PMC article.
pH-Responsive Nanoparticles for Cancer Immunotherapy: A Brief Review.
Yunfeng Yan, Hangwei Ding.
Nanomaterials (Basel), 2020 Aug 23; 10(8). PMID: 32824578    Free PMC article.
Engineered bovine serum albumin-based nanoparticles with pH-sensitivity for doxorubicin delivery and controlled release.
Zhihang Yang, Na Zhang, +3 authors, Hui Xie.
Drug Deliv, 2020 Aug 07; 27(1). PMID: 32755291    Free PMC article.
Nanoparticle-enhanced chemo-immunotherapy to trigger robust antitumor immunity.
Jingjing Liang, Huifang Wang, +17 authors, Jihong Sun.
Sci Adv, 2020 Sep 15; 6(35). PMID: 32923651    Free PMC article.
Disorder of Coagulation-Fibrinolysis System: An Emerging Toxicity of Anti-PD-1/PD-L1 Monoclonal Antibodies.
Ryo Sato, Kosuke Imamura, +13 authors, Takuro Sakagami.
J Clin Med, 2019 May 31; 8(6). PMID: 31146442    Free PMC article.
Chemically Programmed Vaccines: Iron Catalysis in Nanoparticles Enhances Combination Immunotherapy and Immunotherapy-Promoted Tumor Ferroptosis.
Ane Ruiz-de-Angulo, Marc Bilbao-Asensio, +7 authors, Juan C Mareque-Rivas.
iScience, 2020 Sep 13; 23(9). PMID: 32919370    Free PMC article.
Cancer Stem Cells in Thyroid Tumors: From the Origin to Metastasis.
Veronica Veschi, Francesco Verona, +8 authors, Matilde Todaro.
Front Endocrinol (Lausanne), 2020 Sep 29; 11. PMID: 32982967    Free PMC article.
An implantable blood clot-based immune niche for enhanced cancer vaccination.
Qin Fan, Qingle Ma, +7 authors, Chao Wang.
Sci Adv, 2020 Sep 27; 6(39). PMID: 32978163    Free PMC article.
Screening Cancer Immunotherapy: When Engineering Approaches Meet Artificial Intelligence.
Xingwu Zhou, Moyuan Qu, +9 authors, Ali Khademhosseini.
Adv Sci (Weinh), 2020 Oct 13; 7(19). PMID: 33042756    Free PMC article.
Biomedical Application of Reactive Oxygen Species-Responsive Nanocarriers in Cancer, Inflammation, and Neurodegenerative Diseases.
Jinggong Liu, Yongjin Li, +4 authors, Tianfeng Chen.
Front Chem, 2020 Oct 17; 8. PMID: 33062637    Free PMC article.
Emerging technologies for local cancer treatment.
Corrine Ying Xuan Chua, Jeremy Ho, +2 authors, Alessandro Grattoni.
Adv Ther (Weinh), 2020 Oct 20; 3(9). PMID: 33072860    Free PMC article.
A materials-science perspective on tackling COVID-19.
Zhongmin Tang, Na Kong, +12 authors, Wei Tao.
Nat Rev Mater, 2020 Oct 21; 5(11). PMID: 33078077    Free PMC article.
Neoadjuvant Immune-Checkpoint Blockade in Triple-Negative Breast Cancer: Current Evidence and Literature-Based Meta-Analysis of Randomized Trials.
Daniele Marinelli, Marco Mazzotta, +14 authors, Patrizia Vici.
Cancers (Basel), 2020 Sep 10; 12(9). PMID: 32899209    Free PMC article.
Application of Nanomaterials in Biomedical Imaging and Cancer Therapy.
Sarkar Siddique, James C L Chow.
Nanomaterials (Basel), 2020 Sep 03; 10(9). PMID: 32872399    Free PMC article.
Immunotherapy for Ovarian Cancer: Adjuvant, Combination, and Neoadjuvant.
Chang Yang, Bai-Rong Xia, +3 authors, Wei-Lin Jin.
Front Immunol, 2020 Oct 31; 11. PMID: 33123161    Free PMC article.
Immune checkpoint molecules in natural killer cells as potential targets for cancer immunotherapy.
Yuqing Cao, Xiaoyu Wang, +5 authors, Feng Xu.
Signal Transduct Target Ther, 2020 Oct 31; 5(1). PMID: 33122640    Free PMC article.
Endosomal Organization of CpG Constructs Correlates with Enhanced Immune Activation.
Kwahun Lee, Ziyin N Huang, Chad A Mirkin, Teri W Odom.
Nano Lett, 2020 Aug 14; 20(8). PMID: 32787186    Free PMC article.
Severe Acute Respiratory Syndrome Coronavirus-2 Spike Protein Nanogel as a Pro-Antigen Strategy with Enhanced Protective Immune Responses.
Long Chen, Bo Liu, +7 authors, Peng R Chen.
Small, 2020 Oct 28; 16(46). PMID: 33107685    Free PMC article.
Integrative Analysis of HNF1B mRNA in Human Cancers Based on Data Mining.
Chunhui Nie, Bei Wang, +2 authors, Enfan Zhang.
Int J Med Sci, 2020 Nov 12; 17(18). PMID: 33173410    Free PMC article.
Lipid-Nucleic Acid Complexes: Physicochemical Aspects and Prospects for Cancer Treatment.
Ricardo Gaspar, Filipe Coelho, Bruno F B Silva.
Molecules, 2020 Nov 01; 25(21). PMID: 33126767    Free PMC article.
Microneedles Drug Delivery Systems for Treatment of Cancer: A Recent Update.
Aravindram Attiguppe Seetharam, Hani Choudhry, +7 authors, Afrasim Moin.
Pharmaceutics, 2020 Nov 21; 12(11). PMID: 33212921    Free PMC article.
Bioengineering of nano metal-organic frameworks for cancer immunotherapy.
Gaowei Chong, Jie Zang, +4 authors, Yongyong Li.
Nano Res, 2020 Dec 01; 14(5). PMID: 33250971    Free PMC article.
Advances in engineering local drug delivery systems for cancer immunotherapy.
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Wiley Interdiscip Rev Nanomed Nanobiotechnol, 2020 Apr 08; 12(5). PMID: 32255276    Free PMC article.
Proton-driven transformable nanovaccine for cancer immunotherapy.
Ningqiang Gong, Yuxuan Zhang, +17 authors, Xing-Jie Liang.
Nat Nanotechnol, 2020 Oct 28; 15(12). PMID: 33106640    Free PMC article.
Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy.
Megan M Tu, Hany A Abdel-Hafiz, +10 authors, Dan Theodorescu.
Commun Biol, 2020 Nov 29; 3(1). PMID: 33247183    Free PMC article.
Engineering precision nanoparticles for drug delivery.
Michael J Mitchell, Margaret M Billingsley, +3 authors, Robert Langer.
Nat Rev Drug Discov, 2020 Dec 06; 20(2). PMID: 33277608    Free PMC article.
Cancer Vaccines: Toward the Next Breakthrough in Cancer Immunotherapy.
Yuka Igarashi, Tetsuro Sasada.
J Immunol Res, 2020 Dec 08; 2020. PMID: 33282961    Free PMC article.
Circ0120816 acts as an oncogene of esophageal squamous cell carcinoma by inhibiting miR-1305 and releasing TXNRD1.
Xiaoyong Li, Laichun Song, +3 authors, Ming Xu.
Cancer Cell Int, 2020 Dec 10; 20(1). PMID: 33292234    Free PMC article.
Host Immune Response Triggered by Graphene Quantum-Dot-Mediated Photodynamic Therapy for Oral Squamous Cell Carcinoma.
Xiliu Zhang, Hongyu Li, +7 authors, Dongsheng Yu.
Int J Nanomedicine, 2020 Dec 10; 15. PMID: 33293811    Free PMC article.
Engineering Prodrug Nanomedicine for Cancer Immunotherapy.
Bin Yang, Jing Gao, +2 authors, Haijun Yu.
Adv Sci (Weinh), 2020 Dec 12; 7(23). PMID: 33304763    Free PMC article.
Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges.
John D Martin, Horacio Cabral, Triantafyllos Stylianopoulos, Rakesh K Jain.
Nat Rev Clin Oncol, 2020 Feb 09; 17(4). PMID: 32034288    Free PMC article.
Competitive glucose metabolism as a target to boost bladder cancer immunotherapy.
Julieta Afonso, Lúcio L Santos, Adhemar Longatto-Filho, Fátima Baltazar.
Nat Rev Urol, 2020 Jan 19; 17(2). PMID: 31953517
Lymphatic immunomodulation using engineered drug delivery systems for cancer immunotherapy.
Margaret P Manspeaker, Susan N Thomas.
Adv Drug Deliv Rev, 2020 Oct 16; 160. PMID: 33058931    Free PMC article.
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Integrating Biomaterials and Immunology to Improve Vaccines Against Infectious Diseases.
Lampouguin Yenkoidiok-Douti, Christopher M Jewell.
ACS Biomater Sci Eng, 2020 Dec 15; 6(2). PMID: 33313391    Free PMC article.
Nanoparticle Formulations of Poly (ADP-ribose) Polymerase Inhibitors for Cancer Therapy.
Bijay Singh, Shicheng Yang, Apurva Krishna, Srinivas Sridhar.
Front Chem, 2020 Dec 18; 8. PMID: 33330383    Free PMC article.
Implantable and Injectable Biomaterial Scaffolds for Cancer Immunotherapy.
Jie Li, Yiqian Luo, +3 authors, Changfeng Fu.
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Size-transformable antigen-presenting cell-mimicking nanovesicles potentiate effective cancer immunotherapy.
Weijing Yang, Hongzhang Deng, +9 authors, Xiaoyuan Chen.
Sci Adv, 2020 Dec 15; 6(50). PMID: 33310853    Free PMC article.
Strategies for Cancer Immunotherapy Using Induced Pluripotency Stem Cells-Based Vaccines.
Bruno Bernardes de Jesus, Bruno Miguel Neves, Manuela Ferreira, Sandrina Nóbrega-Pereira.
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Precision Tools in Immuno-Oncology: Synthetic Gene Circuits for Cancer Immunotherapy.
Giuliano Bonfá, Juan Blazquez-Roman, Rita Tarnai, Velia Siciliano.
Vaccines (Basel), 2020 Dec 09; 8(4). PMID: 33287392    Free PMC article.
Cancer Immunotherapy and Application of Nanoparticles in Cancers Immunotherapy as the Delivery of Immunotherapeutic Agents and as the Immunomodulators.
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MRI-traceable theranostic nanoparticles for targeted cancer treatment.
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Anti-Cancer Nanomedicines: A Revolution of Tumor Immunotherapy.
Wei Li, Anghui Peng, +4 authors, Min Cui.
Front Immunol, 2021 Jan 08; 11. PMID: 33408716    Free PMC article.
Transdermal Delivery Systems for Biomolecules.
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BIRC5 is a prognostic biomarker associated with tumor immune cell infiltration.
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Therapeutic Approaches for Metastases from Colorectal Cancer and Pancreatic Ductal Carcinoma.
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Advances in Bio-Based Polymers for Colorectal CancerTreatment: Hydrogels and Nanoplatforms.
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Gels, 2021 Jan 15; 7(1). PMID: 33440908    Free PMC article.
Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer.
Yuyan Jiang, Jiaguo Huang, Cheng Xu, Kanyi Pu.
Nat Commun, 2021 Feb 04; 12(1). PMID: 33531498    Free PMC article.
Biohybrid Nanosystems for Cancer Treatment: Merging the Best of Two Worlds.
Flavia Fontana, Raquél Bartolo, Hélder A Santos.
Adv Exp Med Biol, 2021 Feb 06; 1295. PMID: 33543459
Delivery technologies for in utero gene therapy.
Rohan Palanki, William H Peranteau, Michael J Mitchell.
Adv Drug Deliv Rev, 2020 Nov 13; 169. PMID: 33181188    Free PMC article.
Ionizable lipid nanoparticles for in utero mRNA delivery.
Rachel S Riley, Meghana V Kashyap, +10 authors, Michael J Mitchell.
Sci Adv, 2021 Feb 02; 7(3). PMID: 33523869    Free PMC article.
Peptide functionalized liposomes for receptor targeted cancer therapy.
Matthew R Aronson, Scott H Medina, Michael J Mitchell.
APL Bioeng, 2021 Feb 04; 5(1). PMID: 33532673    Free PMC article.
Nanomedicine-based cancer immunotherapy: recent trends and future perspectives.
Vinoth-Kumar Lakshmanan, Shlok Jindal, +8 authors, Salem Chouaib.
Cancer Gene Ther, 2021 Feb 10; 28(9). PMID: 33558704
DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation.
Xiao Huang, Jasper Z Williams, +10 authors, Tejal A Desai.
Nat Nanotechnol, 2020 Dec 16; 16(2). PMID: 33318641    Free PMC article.
Self-Assembly as a Molecular Strategy to Improve Immunotherapy.
Eugene Froimchuk, Sean T Carey, Camilla Edwards, Christopher M Jewell.
Acc Chem Res, 2020 Oct 20; 53(11). PMID: 33074649    Free PMC article.
Overcoming biological barriers to improve solid tumor immunotherapy.
Anvay Ukidve, Katharina Cu, +2 authors, Samir Mitragotri.
Drug Deliv Transl Res, 2021 Feb 22; 11(6). PMID: 33611770
Tumor-associated macrophage polarization promotes the progression of esophageal carcinoma.
Xin Yuan, Ya Li, +11 authors, Jian Ming Hu.
Aging (Albany NY), 2020 Dec 17; 13(2). PMID: 33323552    Free PMC article.
Methotrexate enhances antigen presentation and maturation of tumour antigen-loaded dendritic cells through NLRP3 inflammasome activation: a strategy for dendritic cell-based cancer vaccine.
Gao-Na Shi, Min Hu, +5 authors, Tiantai Zhang.
Ther Adv Med Oncol, 2021 Feb 23; 13. PMID: 33613696    Free PMC article.
A biomimetic antitumor nanovaccine based on biocompatible calcium pyrophosphate and tumor cell membrane antigens.
Minghui Li, Mengmeng Qin, +7 authors, Qiang Zhang.
Asian J Pharm Sci, 2021 Feb 23; 16(1). PMID: 33613733    Free PMC article.
Testosterone deficiency in men receiving immunotherapy for malignant melanoma.
Madeline Peters, Amy Pearlman, +2 authors, Varun Monga.
Oncotarget, 2021 Feb 23; 12(3). PMID: 33613847    Free PMC article.
Microspheres Encapsulating Immunotherapy Agents Target the Tumor-Draining Lymph Node in Pancreatic Ductal Adenocarcinoma.
Booyeon J Han, Joseph D Murphy, +10 authors, Scott A Gerber.
Immunol Invest, 2020 Jun 06; 49(7). PMID: 32498585    Free PMC article.
CD155-Prognostic and Immunotherapeutic Implications Based on Multiple Analyses of Databases Across 33 Human Cancers.
Hongpan Zhang, Zhihao Yang, +2 authors, BangXian Tan.
Technol Cancer Res Treat, 2021 Feb 13; 20. PMID: 33576304    Free PMC article.
Application of Bionanomaterials in Tumor Immune Microenvironment Therapy.
Jiawei Wang, Yan Bao, Yandan Yao.
J Immunol Res, 2021 Feb 26; 2021. PMID: 33628850    Free PMC article.
Recent advances in materials science: a reinforced approach toward challenges against COVID-19.
Abhinav Saxena, Deepak Khare, +2 authors, Ashutosh Kumar Dubey.
Emergent Mater, 2021 Mar 02; 4(1). PMID: 33644691    Free PMC article.
Targeting the PD-1 Axis with Pembrolizumab for Recurrent or Metastatic Cancer of the Uterine Cervix: A Brief Update.
Yannick Verhoeven, Delphine Quatannens, +5 authors, Peter A van Dam.
Int J Mol Sci, 2021 Mar 07; 22(4). PMID: 33670397    Free PMC article.
Theranostic Tripartite Cancer Terminator Virus for Cancer Therapy and Imaging.
Praveen Bhoopathi, Anjan K Pradhan, +3 authors, Paul B Fisher.
Cancers (Basel), 2021 Mar 07; 13(4). PMID: 33670594    Free PMC article.
Summary From the First Kidney Cancer Research Summit, September 12-13, 2019: A Focus on Translational Research.
Toni K Choueiri, Michael B Atkins, +17 authors, Hans J Hammers.
J Natl Cancer Inst, 2020 May 03; 113(3). PMID: 32359162    Free PMC article.
The Identification and Validation of a Robust Immune-Associated Gene Signature in Cutaneous Melanoma.
Le-Bin Song, Jiao-Chen Luan, +5 authors, Yan Lu.
J Immunol Res, 2021 Mar 11; 2021. PMID: 33688507    Free PMC article.
TIM-3 as a Prognostic Marker and a Potential Immunotherapy Target in Human Malignant Tumors: A Meta-Analysis and Bioinformatics Validation.
Kui Zang, Liangliang Hui, +3 authors, Bin Yao.
Front Oncol, 2021 Mar 12; 11. PMID: 33692946    Free PMC article.
Systematic Review.
Enhancing delivery of small molecule and cell-based therapies for ovarian cancer using advanced delivery strategies.
Joanne O'Dwyer, Roisin E O'Cearbhaill, +4 authors, Eimear B Dolan.
Adv Ther (Weinh), 2021 Mar 13; 3(11). PMID: 33709016    Free PMC article.
Tumor-derived ILT4 induces T cell senescence and suppresses tumor immunity.
Aiqin Gao, Xia Liu, +7 authors, Guangyong Peng.
J Immunother Cancer, 2021 Mar 04; 9(3). PMID: 33653799    Free PMC article.
CRISPR/Cas-Dependent and Nuclease-Free In Vivo Therapeutic Gene Editing.
Ishani Dasgupta, Terence R Flotte, Allison M Keeler.
Hum Gene Ther, 2021 Mar 23; 32(5-6). PMID: 33750221    Free PMC article.
Cyclophosphamide loaded thermo-responsive hydrogel system synergize with a hydrogel cancer vaccine to amplify cancer immunotherapy in a prime-boost manner.
Fan Yang, Kun Shi, +7 authors, Zhiyong Qian.
Bioact Mater, 2021 Mar 30; 6(10). PMID: 33778186    Free PMC article.
Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System.
Tobias Achu Muluh, Zhuo Chen, +4 authors, JingBo Wu.
Int J Nanomedicine, 2021 Apr 02; 16. PMID: 33790556    Free PMC article.
The evolution of commercial drug delivery technologies.
Ava M Vargason, Aaron C Anselmo, Samir Mitragotri.
Nat Biomed Eng, 2021 Apr 03; 5(9). PMID: 33795852
Integrated bioinformatic analysis of HNF1A in human cancers.
Enfan Zhang, Xi Huang, Jingsong He.
J Int Med Res, 2021 Mar 24; 49(3). PMID: 33752475    Free PMC article.
Polysaccharide-based nanomedicines for cancer immunotherapy: A review.
Yujun Zeng, Yufan Xiang, +6 authors, Kui Luo.
Bioact Mater, 2021 Apr 06; 6(10). PMID: 33817416    Free PMC article.
Current status and future perspectives of immunotherapy in bladder cancer treatment.
Zhangsong Wu, Jinjian Liu, Ruixiang Dai, Song Wu.
Sci China Life Sci, 2020 Sep 15; 64(4). PMID: 32926318
Clinical Potential of Kinase Inhibitors in Combination with Immune Checkpoint Inhibitors for the Treatment of Solid Tumors.
Ryuhjin Ahn, Josie Ursini-Siegel.
Int J Mol Sci, 2021 Apr 04; 22(5). PMID: 33807608    Free PMC article.
A Comprehensive Investigation to Reveal the Relationship Between Plasmacytoid Dendritic Cells and Breast Cancer by Multiomics Data Analysis.
Saisai Tian, Li Yan, +4 authors, Weidong Zhang.
Front Cell Dev Biol, 2021 Apr 20; 9. PMID: 33869191    Free PMC article.
Delivery technologies to engineer natural killer cells for cancer immunotherapy.
Rakan El-Mayta, Zijing Zhang, Alex G Hamilton, Michael J Mitchell.
Cancer Gene Ther, 2021 Apr 24; 28(9). PMID: 33888870
Nanotraps for the containment and clearance of SARS-CoV-2.
Min Chen, Jillian Rosenberg, +16 authors, Jun Huang.
Matter, 2021 Apr 29; 4(6). PMID: 33907732    Free PMC article.
Advances in Lipid-Based Nanoparticles for Cancer Chemoimmunotherapy.
Tianqi Wang, Yusuke Suita, +3 authors, Jie Shen.
Pharmaceutics, 2021 May 01; 13(4). PMID: 33918635    Free PMC article.
Recent Advances to Augment NK Cell Cancer Immunotherapy Using Nanoparticles.
Kwang-Soo Kim, Dong-Hwan Kim, Dong-Hyun Kim.
Pharmaceutics, 2021 May 01; 13(4). PMID: 33918941    Free PMC article.
Recent advances on microneedle arrays-mediated technology in cancer diagnosis and therapy.
Vahid Alimardani, Samira Sadat Abolmaali, Ali Mohammad Tamaddon, Mohammad Ashfaq.
Drug Deliv Transl Res, 2020 Aug 03; 11(3). PMID: 32740799
Clinical Therapy of Metastatic Spinal Tumors.
Jie Li, Wenjie Wei, +3 authors, Changfeng Fu.
Front Surg, 2021 May 04; 8. PMID: 33937314    Free PMC article.
Cancer neoantigens as potential targets for immunotherapy.
Weijie Ma, Brian Pham, Tianhong Li.
Clin Exp Metastasis, 2021 May 06; 39(1). PMID: 33950415    Free PMC article.
Immune-related adverse events of checkpoint inhibitors.
Manuel Ramos-Casals, Julie R Brahmer, +7 authors, Maria E Suárez-Almazor.
Nat Rev Dis Primers, 2020 May 10; 6(1). PMID: 32382051
Natural killer cells: of-the-shelf cytotherapy for cancer immunosurveillance.
Leisheng Zhang, Min Liu, +3 authors, Zhongchao Han.
Am J Cancer Res, 2021 May 06; 11(4). PMID: 33948388    Free PMC article.
Considerations for designing preclinical cancer immune nanomedicine studies.
Wen Jiang, Yifan Wang, +2 authors, Betty Y S Kim.
Nat Nanotechnol, 2020 Dec 23; 16(1). PMID: 33349682    Free PMC article.
Patient-Reported Outcomes in Clinical Trials Leading to Cancer Immunotherapy Drug Approvals From 2011 to 2018: A Systematic Review.
Houssein Safa, Monica Tamil, +9 authors, Jad Chahoud.
J Natl Cancer Inst, 2020 Nov 05; 113(5). PMID: 33146385    Free PMC article.
Systematic Review.
Systemic tumour suppression via the preferential accumulation of erythrocyte-anchored chemokine-encapsulating nanoparticles in lung metastases.
Zongmin Zhao, Anvay Ukidve, +9 authors, Samir Mitragotri.
Nat Biomed Eng, 2020 Nov 18; 5(5). PMID: 33199847
Effect of physicochemical properties on in vivo fate of nanoparticle-based cancer immunotherapies.
Yongchao Wang, Jinjin Wang, +5 authors, Xing-Jie Liang.
Acta Pharm Sin B, 2021 May 18; 11(4). PMID: 33996405    Free PMC article.
Biological drug and drug delivery-mediated immunotherapy.
Qingqing Xiao, Xiaotong Li, +4 authors, Wei He.
Acta Pharm Sin B, 2021 May 18; 11(4). PMID: 33996408    Free PMC article.
Multiplex Immunofluorescence Tyramide Signal Amplification for Immune Cell Profiling of Paraffin-Embedded Tumor Tissues.
Sharia Hernandez, Frank Rojas, +3 authors, Edwin Roger Parra.
Front Mol Biosci, 2021 May 18; 8. PMID: 33996912    Free PMC article.
Supramolecular co-assembly of self-adjuvanting nanofibrious peptide hydrogel enhances cancer vaccination by activating MyD88-dependent NF-κB signaling pathway without inflammation.
Qi Su, Huijuan Song, +4 authors, Weiwei Wang.
Bioact Mater, 2021 May 18; 6(11). PMID: 33997486    Free PMC article.
Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis.
Hongjun Li, Zejun Wang, +10 authors, Zhen Gu.
Nat Commun, 2021 May 15; 12(1). PMID: 33986264    Free PMC article.
Hitchhiking on Controlled-Release Drug Delivery Systems: Opportunities and Challenges for Cancer Vaccines.
Lu Han, Ke Peng, +4 authors, Zhi-Xiang Yuan.
Front Pharmacol, 2021 May 28; 12. PMID: 34040536    Free PMC article.
Low-Temperature Photothermal Therapy: Strategies and Applications.
Xiulin Yi, Qiu-Yi Duan, Fu-Gen Wu.
Research (Wash D C), 2021 May 28; 2021. PMID: 34041494    Free PMC article.
Influence of low tumor content on tumor mutational burden estimation by whole-exome sequencing and targeted panel sequencing.
Wenxin Zhang, Ruixia Wang, +21 authors, Jie Huang.
Clin Transl Med, 2021 May 29; 11(5). PMID: 34047470    Free PMC article.
Characterization of the Immune Cell Infiltration Profile in Pancreatic Carcinoma to Aid in Immunotherapy.
De Luo, Fei Kuang, +7 authors, Song Su.
Front Oncol, 2021 Jun 01; 11. PMID: 34055645    Free PMC article.
Nanotechnology synergized immunoengineering for cancer.
Deepak S Chauhan, Anupam Dhasmana, +6 authors, Murali M Yallapu.
Eur J Pharm Biopharm, 2021 Mar 29; 163. PMID: 33774162    Free PMC article.
Local and Targeted Delivery of Immune Checkpoint Blockade Therapeutics.
Xiao Han, Hongjun Li, +2 authors, Zhen Gu.
Acc Chem Res, 2020 Oct 20; 53(11). PMID: 33073988    Free PMC article.
A brand new era of cancer immunotherapy: breakthroughs and challenges.
Ri-Lan Bai, Nai-Fei Chen, Ling-Yu Li, Jiu-Wei Cui.
Chin Med J (Engl), 2021 May 28; 134(11). PMID: 34039862    Free PMC article.
Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.
Fan Yang, Zhenqiang He, +15 authors, Yi Fan.
Nat Commun, 2021 Jun 10; 12(1). PMID: 34103524    Free PMC article.
The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody.
Sheena N Smith, Rajib Schubert, +6 authors, Andreas Plückthun.
Proc Natl Acad Sci U S A, 2021 May 19; 118(21). PMID: 34001602    Free PMC article.
Formulation and Delivery Technologies for mRNA Vaccines.
Chunxi Zeng, Chengxiang Zhang, Patrick G Walker, Yizhou Dong.
Curr Top Microbiol Immunol, 2020 Jun 03;. PMID: 32483657    Free PMC article.
Near Infrared Photoimmunotherapy; A Review of Targets for Cancer Therapy.
Takuya Kato, Hiroaki Wakiyama, +2 authors, Hisataka Kobayashi.
Cancers (Basel), 2021 Jun 03; 13(11). PMID: 34064074    Free PMC article.
Development of IL-15/IL-15Rα sushi domain-IgG4 Fc complexes in Pichia pastoris with potent activities and prolonged half-lives.
Huan Xu, Mingyang Shi, +6 authors, Weihua Xiao.
Microb Cell Fact, 2021 Jun 11; 20(1). PMID: 34107983    Free PMC article.
Magnetic Nanostructures as Emerging Therapeutic Tools to Boost Anti-Tumour Immunity.
Stefano Persano, Pradip Das, Teresa Pellegrino.
Cancers (Basel), 2021 Jun 03; 13(11). PMID: 34073106    Free PMC article.
Cellular based treatment modalities for unresectable hepatocellular carcinoma.
Konstantinos Damiris, Hamza Abbad, Nikolaos Pyrsopoulos.
World J Clin Oncol, 2021 Jun 17; 12(5). PMID: 34131562    Free PMC article.
Immunotherapy in endometrial cancer: rationale, practice and perspectives.
Wenyu Cao, Xinyue Ma, +3 authors, Qing Zhang.
Biomark Res, 2021 Jun 18; 9(1). PMID: 34134781    Free PMC article.
Immunotherapy in AML: a brief review on emerging strategies.
A Moeinafshar, S Hemmati, N Rezaei.
Clin Transl Oncol, 2021 Jun 24; 23(12). PMID: 34160771
Nano-immunotherapy for each stage of cancer cellular immunity: which, why, and what?
Shiyi Zuo, Jiaxuan Song, +3 authors, Jin Sun.
Theranostics, 2021 Jun 24; 11(15). PMID: 34158861    Free PMC article.
The Application of and Strategy for Gold Nanoparticles in Cancer Immunotherapy.
Jia-Shuai He, Shi-Jin Liu, +8 authors, Jing-Hua Pan.
Front Pharmacol, 2021 Jun 25; 12. PMID: 34163367    Free PMC article.
Targeting the extracellular matrix for immunomodulation: applications in drug delivery and cell therapies.
Samira Aghlara-Fotovat, Amanda Nash, +2 authors, Omid Veiseh.
Drug Deliv Transl Res, 2021 Jun 28; 11(6). PMID: 34176099
Employing Drug Delivery Strategies to Overcome Challenges Using TLR7/8 Agonists for Cancer Immunotherapy.
Dhruv Varshney, Sherry Yue Qiu, Tyler P Graf, Kevin J McHugh.
AAPS J, 2021 Jun 29; 23(4). PMID: 34181117
Microfluidic technologies for immunotherapy studies on solid tumours.
K Paterson, S Zanivan, +2 authors, M Zagnoni.
Lab Chip, 2021 Jun 05; 21(12). PMID: 34085677    Free PMC article.
A Review on Cancer Immunotherapy and Applications of Nanotechnology to Chemoimmunotherapy of Different Cancers.
Safiye Akkın, Gamze Varan, Erem Bilensoy.
Molecules, 2021 Jul 03; 26(11). PMID: 34205019    Free PMC article.
4-1BBL as a Mediator of Cross-Talk between Innate, Adaptive, and Regulatory Immunity against Cancer.
Alejandra G Martinez-Perez, Jose J Perez-Trujillo, +5 authors, Roberto Montes-de-Oca-Luna.
Int J Mol Sci, 2021 Jul 03; 22(12). PMID: 34207500    Free PMC article.
Light-Responsive Micelles Loaded With Doxorubicin for Osteosarcoma Suppression.
Jiayi Chen, Chenhong Qian, +5 authors, Gang Chen.
Front Pharmacol, 2021 Jul 06; 12. PMID: 34220512    Free PMC article.
Harnessing molecular recognition for localized drug delivery.
Renjie Liu, Ran Zuo, Gregory A Hudalla.
Adv Drug Deliv Rev, 2021 Jan 24; 170. PMID: 33484737    Free PMC article.
Collective metastasis: coordinating the multicellular voyage.
Emma Wrenn, Yin Huang, Kevin Cheung.
Clin Exp Metastasis, 2021 Jul 14; 38(4). PMID: 34254215    Free PMC article.
Insights Into Dendritic Cells in Cancer Immunotherapy: From Bench to Clinical Applications.
Ahmed Salah, Hao Wang, +4 authors, Yuehong Wu.
Front Cell Dev Biol, 2021 Jul 16; 9. PMID: 34262904    Free PMC article.
3D tumor spheroid microarray for high-throughput, high-content natural killer cell-mediated cytotoxicity.
Sneha Gopal, Seok-Joon Kwon, +3 authors, Jonathan S Dordick.
Commun Biol, 2021 Jul 23; 4(1). PMID: 34290356    Free PMC article.
Improving STING Agonist Delivery for Cancer Immunotherapy Using Biodegradable Mesoporous Silica Nanoparticles.
Kyung Soo Park, Cheng Xu, +2 authors, James J Moon.
Adv Ther (Weinh), 2021 Jul 24; 3(10). PMID: 34295963    Free PMC article.
Potential Role of CD47-Directed Bispecific Antibodies in Cancer Immunotherapy.
Yan Yang, Zheng Yang, Yun Yang.
Front Immunol, 2021 Jul 27; 12. PMID: 34305918    Free PMC article.
The Next-Generation of Combination Cancer Immunotherapy: Epigenetic Immunomodulators Transmogrify Immune Training to Enhance Immunotherapy.
Reza Bayat Mokhtari, Manpreet Sambi, +7 authors, Myron R Szewczuk.
Cancers (Basel), 2021 Jul 25; 13(14). PMID: 34298809    Free PMC article.
A Comprehensive Pan-Cancer Analysis of RBM8A Based on Data Mining.
Nan Mei, Heyan Chen, +2 authors, Chunli Li.
J Oncol, 2021 Jul 31; 2021. PMID: 34326876    Free PMC article.
Overcoming physical stromal barriers to cancer immunotherapy.
Seung Woo Chung, Yunxuan Xie, Jung Soo Suk.
Drug Deliv Transl Res, 2021 Aug 06; 11(6). PMID: 34351575    Free PMC article.
Local Anti-PD-1 Delivery Prevents Progression of Premalignant Lesions in a 4NQO-Oral Carcinogenesis Mouse Model.
Yewen Shi, Tong-Xin Xie, +8 authors, Roberto Rangel.
Cancer Prev Res (Phila), 2021 May 23; 14(8). PMID: 34021022    Free PMC article.
Messing Up the Cancer Stem Cell Chemoresistance Mechanisms Supported by Tumor Microenvironment.
Miriam Gaggianesi, Simone Di Franco, +10 authors, Giorgio Stassi.
Front Oncol, 2021 Aug 07; 11. PMID: 34354950    Free PMC article.
Internalisation and Biological Activity of Nucleic Acids Delivering Cell-Penetrating Peptide Nanoparticles Is Controlled by the Biomolecular Corona.
Annely Lorents, Maria Maloverjan, Kärt Padari, Margus Pooga.
Pharmaceuticals (Basel), 2021 Aug 07; 14(7). PMID: 34358093    Free PMC article.
An Update on Mesoporous Silica Nanoparticle Applications in Nanomedicine.
Elham Rastegari, Yu-Jer Hsiao, +7 authors, Yueh Chien.
Pharmaceutics, 2021 Aug 11; 13(7). PMID: 34371758    Free PMC article.
Personalized Neoantigen-Pulsed DC Vaccines: Advances in Clinical Applications.
Lin Tang, Rui Zhang, Xiaoyu Zhang, Li Yang.
Front Oncol, 2021 Aug 13; 11. PMID: 34381724    Free PMC article.
CpG-Based Nanovaccines for Cancer Immunotherapy.
Wenqiang Chen, Mingxia Jiang, +5 authors, Weifen Zhang.
Int J Nanomedicine, 2021 Aug 14; 16. PMID: 34385817    Free PMC article.
An immune-related prognostic signature for thyroid carcinoma to predict survival and response to immune checkpoint inhibitors.
Pu Wu, Wei Sun, Hao Zhang.
Cancer Immunol Immunother, 2021 Aug 17; 71(3). PMID: 34398303
Identification of a robust signature for clinical outcomes and immunotherapy response in gastric cancer: based on N6-methyladenosine related long noncoding RNAs.
Tenghui Han, Dong Xu, +3 authors, Yanchun Deng.
Cancer Cell Int, 2021 Aug 18; 21(1). PMID: 34399770    Free PMC article.
Advances in technology and applications of nanoimmunotherapy for cancer.
Lei Dou, Xiangdan Meng, Huiyuan Yang, Haifeng Dong.
Biomark Res, 2021 Aug 23; 9(1). PMID: 34419164    Free PMC article.
Nanobody-armed T cells endow CAR-T cells with cytotoxicity against lymphoma cells.
Hongxia Wang, Liyan Wang, +7 authors, Guangxian Xu.
Cancer Cell Int, 2021 Aug 26; 21(1). PMID: 34429118    Free PMC article.
DNA methyltransferase inhibitors combination therapy for the treatment of solid tumor: mechanism and clinical application.
Chunhong Hu, Xiaohan Liu, +2 authors, Fang Wu.
Clin Epigenetics, 2021 Aug 29; 13(1). PMID: 34452630    Free PMC article.
Phytochemicals in Cancer Immune Checkpoint Inhibitor Therapy.
Juwon Lee, Youngjin Han, +7 authors, Yong Sang Song.
Biomolecules, 2021 Aug 28; 11(8). PMID: 34439774    Free PMC article.
Feasibility of Monitoring Tumor Response by Tracking Nanoparticle-Labelled T Cells Using X-ray Fluorescence Imaging-A Numerical Study.
Henrik Kahl, Theresa Staufer, +3 authors, Florian Grüner.
Int J Mol Sci, 2021 Aug 28; 22(16). PMID: 34445443    Free PMC article.
A Contemporary Review of Immune Checkpoint Inhibitors in Advanced Clear Cell Renal Cell Carcinoma.
Eun-Mi Yu, Laura Linville, Matthew Rosenthal, Jeanny B Aragon-Ching.
Vaccines (Basel), 2021 Aug 29; 9(8). PMID: 34452045    Free PMC article.
The chemical biology of IL-12 production via the non-canonical NFkB pathway.
Peter D Koch, Mikael J Pittet, Ralph Weissleder.
RSC Chem Biol, 2021 Aug 31; 1(4). PMID: 34458756    Free PMC article.
A splenic-targeted versatile antigen courier: iPSC wrapped in coalescent erythrocyte-liposome as tumor nanovaccine.
Yuewen Zhai, Xiaorong He, +6 authors, Siwen Li.
Sci Adv, 2021 Aug 27; 7(35). PMID: 34433569    Free PMC article.
The effect of PEGylation on the efficacy and uptake of an immunostimulatory nanoparticle in the tumor immune microenvironment.
Wyatt M Becicka, Peter A Bielecki, +5 authors, Efstathios Karathanasis.
Nanoscale Adv, 2021 Sep 07; 3(17). PMID: 34485818    Free PMC article.
Identification of Target PTEN-Based miR-425 and miR-576 as Potential Diagnostic and Immunotherapeutic Biomarkers of Colorectal Cancer With Liver Metastasis.
Xiaoyun Hu, Qiuchen Chen, +7 authors, Huizhe Wu.
Front Oncol, 2021 Sep 08; 11. PMID: 34490081    Free PMC article.
Therapeutic cancer vaccines revamping: technology advancements and pitfalls.
G Antonarelli, C Corti, +6 authors, G Curigliano.
Ann Oncol, 2021 Sep 10; 32(12). PMID: 34500046    Free PMC article.
YTHDF2 is a Potential Biomarker and Associated with Immune Infiltration in Kidney Renal Clear Cell Carcinoma.
Ganglin Su, Tianshu Liu, +8 authors, Hongbing Mei.
Front Pharmacol, 2021 Sep 14; 12. PMID: 34512342    Free PMC article.
Advancing to the era of cancer immunotherapy.
Yun Wang, Min Wang, Hao-Xiang Wu, Rui-Hua Xu.
Cancer Commun (Lond), 2021 Jun 25; 41(9). PMID: 34165252    Free PMC article.
In vivo delivery of CRISPR-Cas9 therapeutics: Progress and challenges.
Matthew Behr, Jing Zhou, Bing Xu, Hongwei Zhang.
Acta Pharm Sin B, 2021 Sep 16; 11(8). PMID: 34522582    Free PMC article.
Magnetic systems for cancer immunotherapy.
Nicole B Day, William C Wixson, C Wyatt Shields.
Acta Pharm Sin B, 2021 Sep 16; 11(8). PMID: 34522583    Free PMC article.
Protease-triggered bioresponsive drug delivery for the targeted theranostics of malignancy.
Yanan Li, Cangang Zhang, +4 authors, Feifei An.
Acta Pharm Sin B, 2021 Sep 16; 11(8). PMID: 34522585    Free PMC article.
Recent advances in microneedles-mediated transdermal delivery of protein and peptide drugs.
Ting Liu, Minglong Chen, +5 authors, Chuanbin Wu.
Acta Pharm Sin B, 2021 Sep 16; 11(8). PMID: 34522590    Free PMC article.
Immune checkpoint inhibitor combined with anti-angiogenesis agent inhibits metastasis of advanced adenoid cystic carcinoma of the tongue base to the lung: a case report.
Ke Zhang, Hui Wang, Juemin Fang, Qing Xu.
Ann Transl Med, 2021 Sep 18; 9(16). PMID: 34532490    Free PMC article.
Interferon Gamma-Induced Interferon Regulatory Factor 1 Activates Transcription of HHLA2 and Induces Immune Escape of Hepatocellular Carcinoma Cells.
Rui Wang, Hui Guo, +5 authors, Yumei Li.
Inflammation, 2021 Sep 19; 45(1). PMID: 34536158
Building a Fit for Purpose Clinical Trials Infrastructure to Accelerate the Assessment of Novel Hematopoietic Cell Transplantation Strategies and Cellular Immunotherapies.
Steven M Devine, Mary M Horowitz.
J Clin Oncol, 2021 Jan 13; 39(5). PMID: 33434065    Free PMC article.
Targeting Indoleamine 2,3-Dioxygenase 1: Fighting Cancers via Dormancy Regulation.
Chao Yang, Chan-Tat Ng, Dan Li, Lei Zhang.
Front Immunol, 2021 Sep 21; 12. PMID: 34539663    Free PMC article.
p53 Activation Effect in the Balance of T Regulatory and Effector Cell Subsets in Patients With Thyroid Cancer and Autoimmunity.
Andrea Arena, Antonio Stigliano, +6 authors, Alessandra Fierabracci.
Front Immunol, 2021 Sep 21; 12. PMID: 34539667    Free PMC article.
Responsive Dual-Targeting Exosome as a Drug Carrier for Combination Cancer Immunotherapy.
Yuanyuan Fan, Yingshun Zhou, +3 authors, Bo Tang.
Research (Wash D C), 2021 Sep 21; 2021. PMID: 34541546    Free PMC article.
How Do We Meet the Challenge of Chimeric Antigen Receptor T-Cell Therapy for Solid Tumors?
Adam J Schoenfeld, Roisin E O'Cearbhaill.
Cancer J, 2021 Mar 23; 27(2). PMID: 33750073    Free PMC article.
Cancer Biology, Epidemiology, and Treatment in the 21st Century: Current Status and Future Challenges From a Biomedical Perspective.
Patricia Piña-Sánchez, Antonieta Chávez-González, +6 authors, Hector Mayani.
Cancer Control, 2021 Sep 28; 28. PMID: 34565215    Free PMC article.
Firing up the Tumor Microenvironment with Nanoparticle-Based Therapies.
Yunfeng Pan, Xueru Song, Yue Wang, Jia Wei.
Pharmaceutics, 2021 Sep 29; 13(9). PMID: 34575414    Free PMC article.
Advances in the Genetically Engineered KillerRed for Photodynamic Therapy Applications.
Jiexi Liu, Fei Wang, Yang Qin, Xiaolan Feng.
Int J Mol Sci, 2021 Sep 29; 22(18). PMID: 34576293    Free PMC article.
Cellular Immunotherapy and the Lung.
Sorcha Daly, Andrew O'Sullivan, Ronan MacLoughlin.
Vaccines (Basel), 2021 Sep 29; 9(9). PMID: 34579255    Free PMC article.
Short Review on Advances in Hydrogel-Based Drug Delivery Strategies for Cancer Immunotherapy.
Hee Seung Seo, Chi-Pin James Wang, Wooram Park, Chun Gwon Park.
Tissue Eng Regen Med, 2021 Oct 02; 19(2). PMID: 34596839    Free PMC article.
The role of immunotherapy in advanced renal cell carcinoma: Review.
Ercília Rita Mondlane, Pedro Abreu-Mendes, +2 authors, Fernando Mendes.
Int Braz J Urol, 2021 Mar 03; 47(6). PMID: 33650838    Free PMC article.
Myeloid cell-based delivery of IFN-γ reprograms the leukemia microenvironment and induces anti-tumoral immune responses.
Adele Mucci, Gabriele Antonarelli, +13 authors, Bernhard Gentner.
EMBO Mol Med, 2021 Aug 31; 13(10). PMID: 34459560    Free PMC article.
Comprehensive analysis of pan-cancer reveals potential of ASF1B as a prognostic and immunological biomarker.
Xinyao Hu, Hua Zhu, +2 authors, Ximing Xu.
Cancer Med, 2021 Sep 03; 10(19). PMID: 34472711    Free PMC article.
caAtlas: An immunopeptidome atlas of human cancer.
Xinpei Yi, Yuxing Liao, +4 authors, Bing Zhang.
iScience, 2021 Oct 09; 24(10). PMID: 34622160    Free PMC article.
Application of Proteomics in Cancer: Recent Trends and Approaches for Biomarkers Discovery.
Yang Woo Kwon, Han-Seul Jo, +4 authors, Jong Hyuk Yoon.
Front Med (Lausanne), 2021 Oct 12; 8. PMID: 34631760    Free PMC article.
Construction and validation of a novel immune and tumor mutation burden-based prognostic model in lung adenocarcinoma.
Bolun Zhou, Shugeng Gao.
Cancer Immunol Immunother, 2021 Oct 13; 71(5). PMID: 34635925
Construction and Validation of an Immune Cell Signature Score to Evaluate Prognosis and Therapeutic Efficacy in Hepatocellular Carcinoma.
Linfeng Xu, Xingxing Jian, +4 authors, Lu Xie.
Front Genet, 2021 Oct 15; 12. PMID: 34646307    Free PMC article.
NEDD4 E3 ubiquitin protein ligase serves an important role in cutaneous melanoma occurrence and development.
Fang Cheng, Yi Cheng, +5 authors, Runzhi He.
Exp Ther Med, 2021 Oct 16; 22(6). PMID: 34650630    Free PMC article.
Harnessing the immune system against cancer: current immunotherapy approaches and therapeutic targets.
Ayana R Kumar, Aswathy R Devan, +2 authors, Lekshmi R Nath.
Mol Biol Rep, 2021 Oct 22; 48(12). PMID: 34671902    Free PMC article.
Viral Status and Efficacy of Immunotherapy in Hepatocellular Carcinoma: A Systematic Review With Meta-Analysis.
Ziniu Ding, Zhaoru Dong, +8 authors, Tao Li.
Front Immunol, 2021 Oct 19; 12. PMID: 34659220    Free PMC article.
Systematic Review.
Prognostic Value of Immune-Related Multi-IncRNA Signatures Associated With Tumor Microenvironment in Esophageal Cancer.
Jingjing Pang, He Pan, +5 authors, Shu-Yuan Xiao.
Front Genet, 2021 Oct 19; 12. PMID: 34659345    Free PMC article.
Applications of Magnetite Nanoparticles in Cancer Immunotherapies: Present Hallmarks and Future Perspectives.
Qingle Song, Amaneh Javid, Guofang Zhang, Yang Li.
Front Immunol, 2021 Oct 23; 12. PMID: 34675914    Free PMC article.
Multi-omics analysis of m6A modification-related patterns based on m6A regulators and tumor microenvironment infiltration in lung adenocarcinoma.
Xincheng Wu, Zhengping Bai.
Sci Rep, 2021 Oct 24; 11(1). PMID: 34686691    Free PMC article.
Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models.
Kristina Kiisholts, Kaido Kurrikoff, +4 authors, Ülo Langel.
Pharmaceutics, 2021 Oct 24; 13(10). PMID: 34683911    Free PMC article.
Structural analysis and binding sites of inhibitors targeting the CD47/SIRPα interaction in anticancer therapy.
Bo Huang, Zhaoshi Bai, +5 authors, Lingman Ma.
Comput Struct Biotechnol J, 2021 Oct 30; 19. PMID: 34712395    Free PMC article.
Reconstructing the tumor architecture into organoids.
Zhimin Luo, Xingwu Zhou, +6 authors, Ali Khademhosseini.
Adv Drug Deliv Rev, 2021 Jun 22; 176. PMID: 34153370    Free PMC article.
Nanoparticle approaches against SARS-CoV-2 infection.
Yaou Duan, Shuyan Wang, +2 authors, Liangfang Zhang.
Curr Opin Solid State Mater Sci, 2021 Nov 04; 25(6). PMID: 34729031    Free PMC article.
Cytosolic delivery of the immunological adjuvant Poly I:C and cytotoxic drug crystals via a carrier-free strategy significantly amplifies immune response.
Xiaoqing Du, Yuqi Hou, +7 authors, Wei He.
Acta Pharm Sin B, 2021 Nov 04; 11(10). PMID: 34729315    Free PMC article.
Engineering Strategies for Immunomodulatory Cytokine Therapies - Challenges and Clinical Progress.
Ivan S Pires, Paula T Hammond, Darrell J Irvine.
Adv Ther (Weinh), 2021 Nov 05; 4(8). PMID: 34734110    Free PMC article.
Protocol for assessment of the efficiency of CRISPR/Cas RNP delivery to different types of target cells.
Marina A Tyumentseva, Aleksandr I Tyumentsev, Vasiliy G Akimkin.
PLoS One, 2021 Nov 10; 16(11). PMID: 34752487    Free PMC article.
Engineered biomaterials for cancer immunotherapy.
Lulu Cai, Jialu Xu, +4 authors, Kam W Leong.
MedComm (2020), 2020 May 27; 1(1). PMID: 34766108    Free PMC article.
Neoantigen-reactive T cell: An emerging role in adoptive cellular immunotherapy.
Yicheng Zhu, Youkun Qian, +2 authors, Bin Li.
MedComm (2020), 2021 Nov 13; 2(2). PMID: 34766142    Free PMC article.
Selectively down-regulated PD-L1 by albumin-phenformin nanoparticles mediated mitochondrial dysfunction to stimulate tumor-specific immunological response for enhanced mild-temperature photothermal efficacy.
Zaigang Zhou, Ning Jiang, +5 authors, Jianliang Shen.
J Nanobiotechnology, 2021 Nov 20; 19(1). PMID: 34794446    Free PMC article.
Combination of epigenetic regulation with gene therapy-mediated immune checkpoint blockade induces anti-tumour effects and immune response in vivo.
Huapan Fang, Zhaopei Guo, +5 authors, Xuesi Chen.
Nat Commun, 2021 Nov 20; 12(1). PMID: 34795289    Free PMC article.
Intravenously Infused Stem Cells for Cancer Treatment.
Alison R Mercer-Smith, Ingrid A Findlay, Hunter N Bomba, Shawn D Hingtgen.
Stem Cell Rev Rep, 2021 Jun 18; 17(6). PMID: 34138421    Free PMC article.
Neurosurgery at the crossroads of immunology and nanotechnology. New reality in the COVID-19 pandemic.
Vladimir A Ljubimov, Arshia Ramesh, +3 authors, Keith L Black.
Adv Drug Deliv Rev, 2021 Nov 23; 181. PMID: 34808227    Free PMC article.
Near-infrared light triggered multi-hit therapeutic nanosystem for tumor specific photothermal effect amplified signal pathway regulation and ferroptosis.
He Lian, Ping Guan, +2 authors, Zhaoxu Meng.
Bioact Mater, 2021 Nov 26; 9. PMID: 34820556    Free PMC article.
Advances of Nanomedicine in Radiotherapy.
Wei Liu, Bo Chen, +5 authors, Yuanzeng Min.
Pharmaceutics, 2021 Nov 28; 13(11). PMID: 34834172    Free PMC article.
Multifunctional Nanopolymers for Blood-Brain Barrier Delivery and Inhibition of Glioblastoma Growth through EGFR/EGFRvIII, c-Myc, and PD-1.
Rameshwar Patil, Tao Sun, +7 authors, Julia Y Ljubimova.
Nanomaterials (Basel), 2021 Nov 28; 11(11). PMID: 34835657    Free PMC article.
Immune checkpoint inhibitors plus neoadjuvant chemotherapy in early triple-negative breast cancer: a systematic review and meta-analysis.
Yuanfang Xin, Guoshuang Shen, +8 authors, Jiuda Zhao.
BMC Cancer, 2021 Nov 25; 21(1). PMID: 34814874    Free PMC article.
Systematic Review.
Targeted Anti-Tumor Immunotherapy Using Tumor Infiltrating Cells.
Yifan Xie, Feng Xie, +7 authors, Fangfang Zhou.
Adv Sci (Weinh), 2021 Oct 19; 8(22). PMID: 34658167    Free PMC article.
Biomaterials by design: Harnessing data for future development.
Kun Xue, FuKe Wang, +7 authors, Xian Jun Loh.
Mater Today Bio, 2021 Dec 09; 12. PMID: 34877520    Free PMC article.
The Immunotherapy for Colorectal Cancer, Lung Cancer and Pancreatic Cancer.
Shiu-Jau Chen, Shao-Cheng Wang, Yuan-Chuan Chen.
Int J Mol Sci, 2021 Dec 11; 22(23). PMID: 34884642    Free PMC article.
Measurement of the Drug Sensitivity of Single Prostate Cancer Cells.
Fikri Abali, Narges Baghi, +3 authors, Leon W M M Terstappen.
Cancers (Basel), 2021 Dec 11; 13(23). PMID: 34885192    Free PMC article.
Biomimetic nanoparticles deliver mRNAs encoding costimulatory receptors and enhance T cell mediated cancer immunotherapy.
Wenqing Li, Xinfu Zhang, +12 authors, Yizhou Dong.
Nat Commun, 2021 Dec 16; 12(1). PMID: 34907171    Free PMC article.
Beyond Sequencing: Prioritizing and Delivering Neoantigens for Cancer Vaccines.
Alexander S Roesler, Karen S Anderson.
Methods Mol Biol, 2021 Dec 17; 2410. PMID: 34914074
Crossed Pathways for Radiation-Induced and Immunotherapy-Related Lung Injury.
Zengfu Zhang, Jialin Zhou, +4 authors, Dawei Chen.
Front Immunol, 2021 Dec 21; 12. PMID: 34925345    Free PMC article.
Renal clearable nanocarriers: Overcoming the physiological barriers for precise drug delivery and clearance.
Chuanqi Peng, Yingyu Huang, Jie Zheng.
J Control Release, 2020 Mar 21; 322. PMID: 32194171    Free PMC article.
Emerging Nanoparticle Strategies for Modulating Tumor-Associated Macrophage Polarization.
Lu Shi, Hongchen Gu.
Biomolecules, 2021 Dec 25; 11(12). PMID: 34944555    Free PMC article.
Interaction of Supramolecular Congo Red and Congo Red-Doxorubicin Complexes with Proteins for Drug Carrier Design.
Anna Jagusiak, Katarzyna Chłopaś, +2 authors, Irena Roterman.
Pharmaceutics, 2021 Dec 29; 13(12). PMID: 34959309    Free PMC article.
Extracellular Vesicles as an Advanced Delivery Biomaterial for Precision Cancer Immunotherapy.
Shaobo Ruan, Zachary Greenberg, +3 authors, Mei He.
Adv Healthc Mater, 2021 Jul 02; 11(5). PMID: 34197051    Free PMC article.
Nanoparticle designs for delivery of nucleic acid therapeutics as brain cancer therapies.
Johan Karlsson, Kathryn M Luly, Stephany Y Tzeng, Jordan J Green.
Adv Drug Deliv Rev, 2021 Oct 30; 179. PMID: 34715258    Free PMC article.
Targeting regulated cell death in tumor nanomedicines.
Qinghu Zeng, Xiangyi Ma, +3 authors, Liqiang Zhou.
Theranostics, 2022 Jan 04; 12(2). PMID: 34976215    Free PMC article.
Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy.
Bin Ji, Minjie Wei, Bin Yang.
Theranostics, 2022 Jan 07; 12(1). PMID: 34987658    Free PMC article.
Cooperating minimalist nanovaccine with PD-1 blockade for effective and feasible cancer immunotherapy.
Mingxia Jiang, Liping Zhao, +5 authors, Weifen Zhang.
J Adv Res, 2022 Jan 11; 35. PMID: 35003793    Free PMC article.
Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity.
Yash Agarwal, Lauren E Milling, +11 authors, K Dane Wittrup.
Nat Biomed Eng, 2022 Jan 12; 6(2). PMID: 35013574
Microfluidic formulation of nanoparticles for biomedical applications.
Sarah J Shepherd, David Issadore, Michael J Mitchell.
Biomaterials, 2021 May 10; 274. PMID: 33965797    Free PMC article.
Identification of a competing endogenous RNA network related to immune signature in clear cell renal cell carcinoma.
Yuke Zhang, Jiangwen Dai, +5 authors, Peng Zhang.
Aging (Albany NY), 2021 Dec 28; 13(24). PMID: 34958632    Free PMC article.
Challenges and Recent Advances in NK Cell-Targeted Immunotherapies in Solid Tumors.
Guangyu Lian, Thomas Shiu-Kwong Mak, Xueqing Yu, Hui-Yao Lan.
Int J Mol Sci, 2022 Jan 12; 23(1). PMID: 35008589    Free PMC article.
Silk Embolic Material for Catheter-Directed Endovascular Drug Delivery.
Jingjie Hu, Hassan Albadawi, +7 authors, Rahmi Oklu.
Adv Mater, 2021 Oct 26; 34(2). PMID: 34695275    Free PMC article.
Characterization of an Autophagy-Immune Related Genes Score Signature and Prognostic Model and its Correlation with Immune Response for Bladder Cancer.
JunJie Yu, WeiPu Mao, +7 authors, Ming Chen.
Cancer Manag Res, 2022 Jan 14; 14. PMID: 35023971    Free PMC article.
Recent advances in multifunctional nanomaterials for photothermal-enhanced Fenton-based chemodynamic tumor therapy.
Panchanathan Manivasagan, Ara Joe, +5 authors, Eue-Soon Jang.
Mater Today Bio, 2022 Jan 18; 13. PMID: 35036895    Free PMC article.
Deciphering the Immune-Tumor Interplay During Early-Stage Lung Cancer Development via Single-Cell Technology.
Wei-Wei Chen, Wei Liu, +5 authors, Hanjie Li.
Front Oncol, 2022 Jan 21; 11. PMID: 35047383    Free PMC article.
Amniotic fluid stabilized lipid nanoparticles for in utero intra-amniotic mRNA delivery.
Kelsey L Swingle, Margaret M Billingsley, +10 authors, Michael J Mitchell.
J Control Release, 2021 Nov 08; 341. PMID: 34742747    Free PMC article.
The Role of m6A Epigenetic Modification in the Treatment of Colorectal Cancer Immune Checkpoint Inhibitors.
Huan Tong, He Wei, Alhaji Osman Smith, Juan Huang.
Front Immunol, 2022 Jan 25; 12. PMID: 35069586    Free PMC article.
A Novel Ferroptosis-Based Molecular Signature Associated with Biochemical Recurrence-Free Survival and Tumor Immune Microenvironment of Prostate Cancer.
Zhi-Bin Ke, Qi You, +8 authors, Ning Xu.
Front Cell Dev Biol, 2022 Jan 25; 9. PMID: 35071228    Free PMC article.
Antitumor Peptide-Based Vaccine in the Limelight.
Takumi Kumai, Hidekiyo Yamaki, +3 authors, Hiroki Komatsuda.
Vaccines (Basel), 2022 Jan 23; 10(1). PMID: 35062731    Free PMC article.
Opportunities and Challenges of Nanoparticles in Digestive Tumours as Anti-Angiogenic Therapies.
Zhengyang Yang, Wei Deng, +4 authors, Zhongtao Zhang.
Front Oncol, 2022 Jan 28; 11. PMID: 35083147    Free PMC article.
Dual agonist immunostimulatory nanoparticles combine with PD1 blockade for curative neoadjuvant immunotherapy of aggressive cancers.
Prabhani U Atukorale, Taylor J Moon, +4 authors, Efstathios Karathanasis.
Nanoscale, 2022 Jan 14; 14(4). PMID: 35023530    Free PMC article.
DNA Damage Repair in Brain Tumor Immunotherapy.
Shihong Zhao, Boya Xu, +4 authors, Xiangqi Meng.
Front Immunol, 2022 Feb 01; 12. PMID: 35095931    Free PMC article.
Development and immunobiological evaluation of nanoparticles containing an immunodominant epitope of herpes simplex virus.
Gabriel M Hilario, Fernando B Sulczewski, +8 authors, Luiz C Rodrigues Junior.
IET Nanobiotechnol, 2021 Oct 26; 15(6). PMID: 34694744    Free PMC article.
The long noncoding RNA noncoding RNA activated by DNA damage (NORAD)-microRNA-496-Interleukin-33 axis affects carcinoma-associated fibroblasts-mediated gastric cancer development.
Chaoqun Huang, Jiuyang Liu, +4 authors, Xiaojun Yang.
Bioengineered, 2021 Dec 14; 12(2). PMID: 34895039    Free PMC article.
MACSima imaging cyclic staining (MICS) technology reveals combinatorial target pairs for CAR T cell treatment of solid tumors.
Ali Kinkhabwala, Christoph Herbel, +27 authors, Andreas Bosio.
Sci Rep, 2022 Feb 05; 12(1). PMID: 35115587    Free PMC article.
Synthesis and use of an amphiphilic dendrimer for siRNA delivery into primary immune cells.
Jiaxuan Chen, Aleksandra Ellert-Miklaszewska, +12 authors, Ling Peng.
Nat Protoc, 2020 Dec 06; 16(1). PMID: 33277630    Free PMC article.
Mapk14 is a Prognostic Biomarker and Correlates with the Clinicopathological Features and Immune Infiltration of Colorectal Cancer.
Dan Wang, Li Peng, +3 authors, Yanhong Zhou.
Front Cell Dev Biol, 2022 Feb 11; 10. PMID: 35141222    Free PMC article.
Pan-cancer analysis reveals NUP37 as a prognostic biomarker correlated with the immunosuppressive microenvironment in glioma.
Ya He, Jingang Li, +6 authors, Yuetao Wen.
Aging (Albany NY), 2022 Jan 31; 14(2). PMID: 35093934    Free PMC article.
Semaphorins as Potential Immune Therapeutic Targets for Cancer.
Jun Jiang, Fang Zhang, +4 authors, Rui Zhang.
Front Oncol, 2022 Feb 15; 12. PMID: 35155237    Free PMC article.
Graphene as Photothermal Therapeutic Agents.
Vishnu Revuri, Jagannath Mondal, Yong-Kyu Lee.
Adv Exp Med Biol, 2022 Feb 18; 1351. PMID: 35175617
Functional and Therapeutic Significance of Tumor-Associated Macrophages in Colorectal Cancer.
Yitong Li, Zhenmei Chen, +3 authors, Jinhong Chen.
Front Oncol, 2022 Feb 22; 12. PMID: 35186730    Free PMC article.
Effective Combinations of Immunotherapy and Radiotherapy for Cancer Treatment.
Siting Yu, Yang Wang, +9 authors, Lei Liu.
Front Oncol, 2022 Feb 25; 12. PMID: 35198442    Free PMC article.
RFC2: a prognosis biomarker correlated with the immune signature in diffuse lower-grade gliomas.
Xu Zhao, Yuzhu Wang, +6 authors, Xiaozhi Zhang.
Sci Rep, 2022 Feb 26; 12(1). PMID: 35210438    Free PMC article.
Typical tumor immune microenvironment status determine prognosis in lung adenocarcinoma.
Caixia Ren, Jinyu Li, +2 authors, Qi Wang.
Transl Oncol, 2022 Feb 18; 18. PMID: 35176624    Free PMC article.
Clinical Significance of BTLA, CD27, CD70, CD28 and CD80 as Diagnostic and Prognostic Markers in Ovarian Cancer.
Janina Świderska, Mateusz Kozłowski, +4 authors, Aneta Cymbaluk-Płoska.
Diagnostics (Basel), 2022 Feb 26; 12(2). PMID: 35204342    Free PMC article.
Discovering the Triad between Nav1.5, Breast Cancer, and the Immune System: A Fundamental Review and Future Perspectives.
Harishini Rajaratinam, Noor Fatmawati Mokhtar, Nurul Asma-Abdullah, Wan Ezumi Mohd Fuad.
Biomolecules, 2022 Feb 26; 12(2). PMID: 35204811    Free PMC article.
The Role of Long Non-Coding RNAs in the Tumor Immune Microenvironment.
Yingli Guo, Yajuan Xie, Yao Luo.
Front Immunol, 2022 Mar 01; 13. PMID: 35222443    Free PMC article.
A Necroptosis-Related Prognostic Model of Uveal Melanoma Was Constructed by Single-Cell Sequencing Analysis and Weighted Co-Expression Network Analysis Based on Public Databases.
Jiaheng Xie, Liang Chen, +7 authors, Ming Wang.
Front Immunol, 2022 Mar 05; 13. PMID: 35242144    Free PMC article.
Recent Advance of Nanomaterial-Mediated Tumor Therapies in the Past Five Years.
Xinyan Hao, Junyong Wu, DaXiong Xiang, Yongyu Yang.
Front Pharmacol, 2022 Mar 08; 13. PMID: 35250598    Free PMC article.
Deep learning using bulk RNA-seq data expands cell landscape identification in tumor microenvironment.
Xin Wang, Hongjiu Wang, +8 authors, Zhenzhen Wang.
Oncoimmunology, 2022 Mar 08; 11(1). PMID: 35251771    Free PMC article.
Combining nanomedicine and immune checkpoint therapy for cancer immunotherapy.
Christine E Boone, Lu Wang, +2 authors, Nicole F Steinmetz.
Wiley Interdiscip Rev Nanomed Nanobiotechnol, 2021 Jul 24; 14(1). PMID: 34296535    Free PMC article.
Polymeric microneedle-mediated sustained release systems: Design strategies and promising applications for drug delivery.
Li Yang, Yao Yang, +2 authors, Xiaowei Zeng.
Asian J Pharm Sci, 2022 Mar 10; 17(1). PMID: 35261645    Free PMC article.
Neutrophil Extracellular Traps in Cancer Therapy Resistance.
Muhammad H Shahzad, Lixuan Feng, +5 authors, Jonathan J Cools-Lartigue.
Cancers (Basel), 2022 Mar 11; 14(5). PMID: 35267667    Free PMC article.
Image-Guided High-Intensity Focused Ultrasound, A Novel Application for Interventional Nuclear Medicine?
Xinrui Zhang, Lisa Landgraf, +3 authors, Andreas Melzer.
J Nucl Med, 2021 Jun 06; 62(9). PMID: 34088775    Free PMC article.
Clinically translatable cytokine delivery platform for eradication of intraperitoneal tumors.
Amanda M Nash, Maria I Jarvis, +18 authors, Omid Veiseh.
Sci Adv, 2022 Mar 03; 8(9). PMID: 35235346    Free PMC article.
Exploring Immune-Related Prognostic Signatures in the Tumor Microenvironment of Colon Cancer.
Lichao Cao, Tong Li, +3 authors, Hezi Zhang.
Front Genet, 2022 Mar 15; 13. PMID: 35281839    Free PMC article.
Generation and Analysis of Pyroptosis-Based and Immune-Based Signatures for Kidney Renal Clear Cell Carcinoma Patients, and Cell Experiment.
Gaoteng Lin, Qingfu Feng, +3 authors, Gang Li.
Front Genet, 2022 Mar 15; 13. PMID: 35281845    Free PMC article.
Immune checkpoint silencing using RNAi-incorporated nanoparticles enhances antitumor immunity and therapeutic efficacy compared with antibody-based approaches.
Ji Eun Won, Youngseon Byeon, +7 authors, Hee Dong Han.
J Immunother Cancer, 2022 Mar 02; 10(2). PMID: 35228265    Free PMC article.
Doxorubicin and CpG loaded liposomal spherical nucleic acid for enhanced Cancer treatment.
Bo Deng, Bing Ma, +7 authors, Lanxia Liu.
J Nanobiotechnology, 2022 Mar 20; 20(1). PMID: 35303868    Free PMC article.
Redox dyshomeostasis strategy for tumor therapy based on nanomaterials chemistry.
Yelin Wu, Yanli Li, Guanglei Lv, Wenbo Bu.
Chem Sci, 2022 Mar 22; 13(8). PMID: 35310479    Free PMC article.
TCN1 is a potential prognostic biomarker and correlates with immune infiltrates in lung adenocarcinoma.
Haining Li, Liping Guo, Zhigang Cai.
World J Surg Oncol, 2022 Mar 16; 20(1). PMID: 35287670    Free PMC article.
A three-dimensional immune-oncology model for studying in vitro primary human NK cell cytotoxic activity.
Nontaphat Thongsin, Methichit Wattanapanitch.
PLoS One, 2022 Mar 22; 17(3). PMID: 35312698    Free PMC article.
Advances in High Throughput Proteomics Profiling in Establishing Potential Biomarkers for Gastrointestinal Cancer.
Md Zahirul Islam Khan, Shing Yau Tam, Helen Ka Wai Law.
Cells, 2022 Mar 26; 11(6). PMID: 35326424    Free PMC article.
LAMC1 is a Novel Prognostic Factor and a Potential Therapeutic Target in Gastric Cancer.
Dayong Xi, Qiufang Jia, +7 authors, Hao Chen.
Int J Gen Med, 2022 Mar 29; 15. PMID: 35342300    Free PMC article.
Promoting antibody-dependent cellular phagocytosis for effective macrophage-based cancer immunotherapy.
Xu Cao, Jing Chen, +9 authors, Mingye Feng.
Sci Adv, 2022 Mar 19; 8(11). PMID: 35302839    Free PMC article.
Comprehensive comparison of theranostic nanoparticles in breast cancer.
Amin Nikdouz, Nima Namarvari, Ramin Ghasemi Shayan, Arezoo Hosseini.
Am J Clin Exp Immunol, 2022 Mar 31; 11(1). PMID: 35350450    Free PMC article.
Cross-Talk Between m6A- and m5C-Related lncRNAs to Construct a Novel Signature and Predict the Immune Landscape of Colorectal Cancer Patients.
Wei Song, Jun Ren, +2 authors, Tao Fu.
Front Immunol, 2022 Mar 31; 13. PMID: 35350786    Free PMC article.
Mapping the Mechanical and Immunological Profiles of Polymeric Microneedles to Enable Vaccine and Immunotherapy Applications.
Shrey A Shah, Robert S Oakes, Senta M Kapnick, Christopher M Jewell.
Front Immunol, 2022 Apr 02; 13. PMID: 35359943    Free PMC article.
Role of TFRC as a Novel Prognostic Biomarker and in Immunotherapy for Pancreatic Carcinoma.
Cheng Yang, Junqiang Li, +9 authors, Haichuan Su.
Front Mol Biosci, 2022 Apr 05; 9. PMID: 35372510    Free PMC article.
Depletion of tumor associated macrophages enhances local and systemic platelet-mediated anti-PD-1 delivery for post-surgery tumor recurrence treatment.
Zhaoting Li, Yingyue Ding, +7 authors, Quanyin Hu.
Nat Commun, 2022 Apr 08; 13(1). PMID: 35387972    Free PMC article.
Biomaterial-assisted biotherapy: A brief review of biomaterials used in drug delivery, vaccine development, gene therapy, and stem cell therapy.
Xuejiao Han, Aqu Alu, +4 authors, Yuquan Wei.
Bioact Mater, 2022 Apr 08; 17. PMID: 35386442    Free PMC article.
The promise and challenge of therapeutic genome editing.
Jennifer A Doudna.
Nature, 2020 Feb 14; 578(7794). PMID: 32051598    Free PMC article.
Chemical and Biomolecular Strategies for STING Pathway Activation in Cancer Immunotherapy.
Kyle M Garland, Taylor L Sheehy, John T Wilson.
Chem Rev, 2022 Feb 03; 122(6). PMID: 35107989    Free PMC article.
Role of macrophages in tumor progression and therapy (Review).
Yiwei Xu, Xiaomin Wang, +3 authors, Changgang Sun.
Int J Oncol, 2022 Apr 02; 60(5). PMID: 35362544    Free PMC article.
Research Progress on Gene Editing Based on Nano-Drug Delivery Vectors for Tumor Therapy.
Shiwen Xi, Yong-Guang Yang, Jian Suo, Tianmeng Sun.
Front Bioeng Biotechnol, 2022 Apr 15; 10. PMID: 35419357    Free PMC article.
Resident memory CD8+ T cells in regional lymph nodes mediate immunity to metastatic melanoma.
Aleksey K Molodtsov, Nikhil Khatwani, +21 authors, Mary Jo Turk.
Immunity, 2021 Sep 16; 54(9). PMID: 34525340    Free PMC article.
Improving cancer immunotherapy through nanotechnology.
Michael S Goldberg.
Nat Rev Cancer, 2019 Sep 08; 19(10). PMID: 31492927
Highly Cited. Review.
Overcoming the challenge of long-term storage of mRNA-lipid nanoparticle vaccines.
Rachel E Young, Samuel I Hofbauer, Rachel S Riley.
Mol Ther, 2022 Apr 23; 30(5). PMID: 35452599    Free PMC article.
Engineering a High-Affinity PD-1 Peptide for Optimized Immune Cell-Mediated Tumor Therapy.
Yilei Chen, Hongxing Huang, +5 authors, Hua Wang.
Cancer Res Treat, 2021 Aug 07; 54(2). PMID: 34352997    Free PMC article.
Advances in the Immunomodulatory Properties of Glycoantigens in Cancer.
Valeria da Costa, Teresa Freire.
Cancers (Basel), 2022 Apr 24; 14(8). PMID: 35454762    Free PMC article.
Immunotherapeutic nanoparticles: From autoimmune disease control to the development of vaccines.
Romina Mitarotonda, Exequiel Giorgi, +6 authors, Gorka Orive.
Biomater Adv, 2022 Apr 28; 135. PMID: 35475005    Free PMC article.
Hypereosinophilia is a predictive biomarker of immune checkpoint inhibitor-induced hypopituitarism in patients with renal cell carcinoma.
Hodaka Yamada, Satoshi Washino, +9 authors, Kazuo Hara.
BMC Endocr Disord, 2022 Apr 27; 22(1). PMID: 35468815    Free PMC article.
Identification of a Gene Signature to Aid Treatment Decisions by Integrated Analysis of Mutated Genes Between Primary and Metastatic Prostate Cancer.
Qinyu Li, Xueyan Xiao, +3 authors, Jianping Miao.
Front Genet, 2022 May 03; 13. PMID: 35495154    Free PMC article.
Harnessing the Immunogenic Potential of Gold Nanoparticle-Based Platforms as a Therapeutic Strategy in Breast Cancer Immunotherapy: A Mini Review.
Xiao-Yang Chen, Lin-Yue Lanry Yung, Puay Hoon Tan, Boon Huat Bay.
Front Immunol, 2022 Apr 19; 13. PMID: 35432376    Free PMC article.
Size dependent anti-invasiveness of silver nanoparticles in lung cancer cells.
Yu Mei Que, Xiao Qing Fan, +4 authors, Qun You Tan.
RSC Adv, 2019 Jul 05; 9(37). PMID: 35521328    Free PMC article.
Chemo-photothermal immunotherapy for eradication of orthotopic tumors and inhibition of metastasis by intratumoral injection of polydopamine versatile hydrogels.
Bo Zhuang, Ting Chen, +2 authors, Yiguang Jin.
Acta Pharm Sin B, 2022 May 10; 12(3). PMID: 35530148    Free PMC article.
Self-Assembly Catalase Nanocomplex Conveyed by Bacterial Vesicles for Oxygenated Photodynamic Therapy and Tumor Immunotherapy.
Jiayu Zhang, Zinan Li, +4 authors, Jia Zhao.
Int J Nanomedicine, 2022 May 10; 17. PMID: 35530972    Free PMC article.
Harnessing the Anti-Tumor Mediators in Mast Cells as a New Strategy for Adoptive Cell Transfer for Cancer.
Mohammad Fereydouni, Mona Motaghed, +4 authors, Christopher L Kepley.
Front Oncol, 2022 Apr 19; 12. PMID: 35433433    Free PMC article.
Integrative Multi-Omics Analysis of Identified SKA3 as a Candidate Oncogene Correlates with Poor Prognosis and Immune Infiltration in Lung Adenocarcinoma.
Yuansheng Lin, Jianzhong An, +10 authors, Shengjun Li.
Int J Gen Med, 2022 May 11; 15. PMID: 35535142    Free PMC article.
Construction of a Risk Model to Predict the Prognosis and Immunotherapy of Low-Grade Glioma Ground on 7 Ferroptosis-Related Genes.
Liwei Sun, Bing Li, +2 authors, Jing Li.
Int J Gen Med, 2022 May 14; 15. PMID: 35548585    Free PMC article.
Albumin Binds Doxorubicin via Self-Assembling Dyes as Specific Polymolecular Ligands.
Anna Jagusiak, Katarzyna Chłopaś, +3 authors, Barbara Stopa.
Int J Mol Sci, 2022 May 15; 23(9). PMID: 35563426    Free PMC article.
mRNA-based therapeutics: powerful and versatile tools to combat diseases.
Shugang Qin, Xiaoshan Tang, +8 authors, Xiangrong Song.
Signal Transduct Target Ther, 2022 May 22; 7(1). PMID: 35597779    Free PMC article.
Emerging Potential of Plant Virus Nanoparticles (PVNPs) in Anticancer Immunotherapies.
Mehdi Shahgolzari, Steven Fiering.
J Cancer Immunol (Wilmington), 2022 May 24; 4(1). PMID: 35600219    Free PMC article.
Salvia miltiorrhiza in Breast Cancer Treatment: A Review of Its Phytochemistry, Derivatives, Nanoparticles, and Potential Mechanisms.
Huan Zhao, Bing Han, +7 authors, Guoyin Kai.
Front Pharmacol, 2022 May 24; 13. PMID: 35600860    Free PMC article.