Review
. 2019 Dec; 9(12):.
doi: 10.3390/nano9121719.

A Comprehensive Review on the Synthesis, Characterization, and Biomedical Application of Platinum Nanoparticles

Muniyandi Jeyaraj 1 Sangiliyandi Gurunathan 1 Muhammad Qasim 1 Min-Hee Kang 1 Jin-Hoi Kim 1 
Affiliations
  • PMID: 31810256
  •     170 References
  •     22 citations

Abstract

Platinum nanoparticles (PtNPs) are noteworthy scientific tools that are being explored in various biotechnological, nanomedicinal, and pharmacological fields. They are unique because of their large surface area and their numerous catalytic applications such as their use in automotive catalytic converters and as petrochemical cracking catalysts. PtNPs have been widely utilized not only in the industry, but also in medicine and diagnostics. PtNPs are extensively studied because of their antimicrobial, antioxidant, and anticancer properties. So far, only one review has been dedicated to the application of PtNPs to nanomedicine. However, no studies describe the synthesis, characterization, and biomedical application of PtNPs. Therefore, the aim of this review is to provide a comprehensive assessment of the current knowledge regarding the synthesis, including physical, chemical, and biological and toxicological effects of PtNPs on human health, in terms of both in vivo and in vitro experimental analysis. Special attention has been focused on the biological synthesis of PtNPs using various templates as reducing and stabilizing agents. Finally, we discuss the biomedical and other applications of PtNPs.

Keywords: anticancer; biomedical applications; characterization; combination therapy; cytotoxicity; synthesis.

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Antiviral Potential of Nanoparticles-Can Nanoparticles Fight Against Coronaviruses?
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First principle simulation of coated hydroxychloroquine on Ag, Au and Pt nanoparticles.
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Platinum Nanoparticles Enhance Exosome Release in Human Lung Epithelial Adenocarcinoma Cancer Cells (A549): Oxidative Stress and the Ceramide Pathway are Key Players.
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Bacteriogenic Platinum Nanoparticles for Application in Nanomedicine.
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Green synthesis of metal nanoparticles using microorganisms and their application in the agrifood sector.
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Corrosion and transformation of solution combustion synthesized Co, Ni and CoNi nanoparticles in synthetic freshwater with and without natural organic matter.
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Au@Pt Core-Shell Nanoparticle Bioconjugates for the Therapy of HER2+ Breast Cancer and Hepatocellular Carcinoma. Model Studies on the Applicability of 193mPt and 195mPt Radionuclides in Auger Electron Therapy.
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Green Synthesis of Platinum and Palladium Nanoparticles Using Peganum harmala L. Seed Alkaloids: Biological and Computational Studies.
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Carbon Dots as Promising Tools for Cancer Diagnosis and Therapy.
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Nanoarchitectonics for Hierarchical Fullerene Nanomaterials.
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The Recent Progress on Silver Nanoparticles: Synthesis and Electronic Applications.
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