Journal Article
. 2018 Jul; 16(7):e05361.
doi: 10.2903/j.efsa.2018.5361.

Safety of xylo-oligosaccharides (XOS) as a novel food pursuant to Regulation (EU) 2015/2283

EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)  Dominique Turck  Jean-Louis Bresson  Barbara Burlingame  Tara Dean  Susan Fairweather-Tait  Marina Heinonen  Karen Ildico Hirsch-Ernst  Inge Mangelsdorf  Harry J McArdle  Androniki Naska  Monika Neuhäuser-Berthold  Grażyna Nowicka  Kristina Pentieva  Yolanda Sanz  Alfonso Siani  Anders Sjödin  Martin Stern  Daniel Tomé  Marco Vinceti  Peter Willatts  Karl-Heinz Engel  Rosangela Marchelli  Annette Pöting  Morten Poulsen  Josef Rudolf Schlatter  Emanuela Turla  Henk van Loveren  
  • PMID: 32625993
  •     12 References
  •     7 citations


Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a scientific opinion on a mixture of xylo-oligosaccharides (XOS) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is obtained from corncobs (Zea mays subsp. mays) via enzyme-catalysed hydrolysis and subsequent purification. The main components of the NF, the oligosaccharides, are resistant to human digestive enzymes and are fermented by colonic bacteria. The intention is to add the NF to a variety of foods such as bakery and dairy products, fruit jelly, chocolates and soy-drinks. The information provided on composition, specifications, production process and stability of the NF, does not raise safety concerns. There were effects observed in the animal studies with the NF or with other XOS which were considered by the Panel to be expected from the intake of non-digestible carbohydrates. The Panel notes that the acute and transient gastrointestinal observed in human intervention studies with the NF or with other XOS have also been associated with the consumption of other non-digestible carbohydrates. The Panel concludes that the NF, a mixture of XOS, is safe under the proposed uses and use levels. The target population is the general population.

Keywords: XOS; novel food; safety; xylo‐oligosaccharides.

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