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Combined Antitumor Effects of Sorafenib and GPC3-CAR T Cells in Mouse Models of Hepatocellular Carcinoma. Xiuqi Wu, Hong Luo, +7 authors, Bizhi Shi, Shengmeng Di, Ruixin Sun, Jingwen Su, Ying Liu, Hua Li, Hua Jiang, Zonghai Li. less Mol Ther, 2019 May 13; 27(8). PMID: 31078430 Free PMC article.
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Pembrolizumab As Second-Line Therapy in Patients With Advanced Hepatocellular Carcinoma in KEYNOTE-240: A Randomized, Double-Blind, Phase III Trial. Richard S Finn, Baek-Yeol Ryoo, +18 authors, Philippe Merle, Masatoshi Kudo, Mohamed Bouattour, Ho Yeong Lim, Valeriy Breder, Julien Edeline, Yee Chao, Sadahisa Ogasawara, Thomas Yau, Marcelo Garrido, Stephen L Chan, Jennifer Knox, Bruno Daniele, Scot W Ebbinghaus, Erluo Chen, Abby B Siegel, Andrew X Zhu, Ann-Lii Cheng, KEYNOTE-240 investigators. less J Clin Oncol, 2019 Dec 04; 38(3). PMID: 31790344 Highly Cited.
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Glypican-3-Specific CAR T Cells Coexpressing IL15 and IL21 Have Superior Expansion and Antitumor Activity against Hepatocellular Carcinoma. Sai Arun Batra, Purva Rathi, +10 authors, Linjie Guo, Amy N Courtney, Julien Fleurence, Julien Balzeau, Rahamthulla S Shaik, Thao P Nguyen, Meng-Fen Wu, Shaun Bulsara, Maksim Mamonkin, Leonid S Metelitsa, Andras Heczey. less Cancer Immunol Res, 2020 Jan 19; 8(3). PMID: 31953246
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Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma. Zhiwu Jiang, Xiaofeng Jiang, +17 authors, Suimin Chen, Yunxin Lai, Xinru Wei, Baiheng Li, Simiao Lin, Suna Wang, Qiting Wu, Qiubin Liang, Qifa Liu, Muyun Peng, Fenglei Yu, Jianyu Weng, Xin Du, Duanqing Pei, Pentao Liu, Yao Yao, Ping Xue, Peng Li. less Front Immunol, 2017 Jan 27; 7. PMID: 28123387 Free PMC article.
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Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors. Gregory T Motz, Stephen P Santoro, +7 authors, Li-Ping Wang, Tom Garrabrant, Ricardo R Lastra, Ian S Hagemann, Priti Lal, Michael D Feldman, Fabian Benencia, George Coukos. less Nat Med, 2014 May 06; 20(6). PMID: 24793239 Free PMC article. Highly Cited.
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HER2 CAR-T Cells Eradicate Uveal Melanoma and T-cell Therapy-Resistant Human Melanoma in IL2 Transgenic NOD/SCID IL2 Receptor Knockout Mice. Elin M V Forsberg, Mattias F Lindberg, +8 authors, Henrik Jespersen, Samuel Alsén, Roger Olofsson Bagge, Marco Donia, Inge Marie Svane, Ola Nilsson, Lars Ny, Lisa M Nilsson, Jonas A Nilsson. less Cancer Res, 2019 Jan 10; 79(5). PMID: 30622115
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Effect of everolimus on survival in advanced hepatocellular carcinoma after failure of sorafenib: the EVOLVE-1 randomized clinical trial. Andrew X Zhu, Masatoshi Kudo, +17 authors, Eric Assenat, Stéphane Cattan, Yoon-Koo Kang, Ho Yeong Lim, Ronnie T P Poon, Jean-Frederic Blanc, Arndt Vogel, Chao-Long Chen, Etienne Dorval, Markus Peck-Radosavljevic, Armando Santoro, Bruno Daniele, Junji Furuse, Annette Jappe, Kevin Perraud, Oezlem Anak, Dalila B Sellami, Li-Tzong Chen. less JAMA, 2014 Jul 25; 312(1). PMID: 25058218 Highly Cited.
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Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer. Ivy X Chen, Vikash P Chauhan, +7 authors, Jessica Posada, Mei R Ng, Michelle W Wu, Pichet Adstamongkonkul, Peigen Huang, Neal Lindeman, Robert Langer, Rakesh K Jain. less Proc Natl Acad Sci U S A, 2019 Feb 01; 116(10). PMID: 30700545 Free PMC article. Highly Cited.
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Decreased expression of B7 costimulatory molecules and major histocompatibility complex class-I in human hepatocellular carcinoma. Keishi Fujiwara, Toshihiro Higashi, +9 authors, Kazuhiro Nouso, Harushige Nakatsukasa, Yoshiyuki Kobayashi, Masayuki Uemura, Shin-Ichiro Nakamura, Shuichiro Sato, Tadashi Hanafusa, Yasuhiro Yumoto, Ichiro Naito, Yasushi Shiratori. less J Gastroenterol Hepatol, 2004 Sep 21; 19(10). PMID: 15377288
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Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma. James Larkin, Vanna Chiarion-Sileni, +28 authors, Rene Gonzalez, Jean-Jacques Grob, Piotr Rutkowski, Christopher D Lao, C Lance Cowey, Dirk Schadendorf, John Wagstaff, Reinhard Dummer, Pier F Ferrucci, Michael Smylie, David Hogg, Andrew Hill, Ivan Márquez-Rodas, John Haanen, Massimo Guidoboni, Michele Maio, Patrick Schöffski, Matteo S Carlino, Céleste Lebbé, Grant McArthur, Paolo A Ascierto, Gregory A Daniels, Georgina V Long, Lars Bastholt, Jasmine I Rizzo, Agnes Balogh, Andriy Moshyk, F Stephen Hodi, Jedd D Wolchok. less N Engl J Med, 2019 Sep 29; 381(16). PMID: 31562797 Highly Cited.
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Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma. Richard S Finn, Shukui Qin, +19 authors, Masafumi Ikeda, Peter R Galle, Michel Ducreux, Tae-You Kim, Masatoshi Kudo, Valeriy Breder, Philippe Merle, Ahmed O Kaseb, Daneng Li, Wendy Verret, Derek-Zhen Xu, Sairy Hernandez, Juan Liu, Chen Huang, Sohail Mulla, Yulei Wang, Ho Yeong Lim, Andrew X Zhu, Ann-Lii Cheng, IMbrave150 Investigators. less N Engl J Med, 2020 May 14; 382(20). PMID: 32402160
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Designing and building oncolytic viruses. Justin Maroun, Miguel Muñoz-Alía, +3 authors, Arun Ammayappan, Autumn Schulze, Kah-Whye Peng, Stephen Russell. less Future Virol, 2018 Feb 02; 12(4). PMID: 29387140 Free PMC article. Highly Cited. Review.
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Development of T cells carrying two complementary chimeric antigen receptors against glypican-3 and asialoglycoprotein receptor 1 for the treatment of hepatocellular carcinoma. Cheng Chen, Kesang Li, +8 authors, Hua Jiang, Fei Song, Huiping Gao, Xiaorong Pan, Bizhi Shi, Yanyu Bi, Huamao Wang, Hongyang Wang, Zonghai Li. less Cancer Immunol Immunother, 2016 Dec 31; 66(4). PMID: 28035433
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Interferon-stimulated genes: a complex web of host defenses. William M Schneider, Meike Dittmann Chevillotte, Charles M Rice. Annu Rev Immunol, 2014 Feb 22; 32. PMID: 24555472 Free PMC article. Highly Cited. Review.
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Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma. Jeffrey J Wallin, Johanna C Bendell, +19 authors, Roel Funke, Mario Sznol, Konstanty Korski, Suzanne Jones, Genevive Hernandez, James Mier, Xian He, F Stephen Hodi, Mitchell Denker, Vincent Leveque, Marta Cañamero, Galina Babitski, Hartmut Koeppen, James Ziai, Neeraj Sharma, Fabien Gaire, Daniel S Chen, Daniel Waterkamp, Priti S Hegde, David F McDermott. less Nat Commun, 2016 Aug 31; 7. PMID: 27571927 Free PMC article. Highly Cited.
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Long noncoding RNA glypican 3 (GPC3) antisense transcript 1 promotes hepatocellular carcinoma progression via epigenetically activating GPC3. Xiao-Ting Zhu, Ji-Hang Yuan, +2 authors, Teng-Teng Zhu, Yang-Yang Li, Xiao-Yang Cheng. less FEBS J, 2016 Oct 21; 283(20). PMID: 27573079 Highly Cited.
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