Isoform-specific activation of latent transforming growth factor beta (LTGF-beta) by reactive oxygen species. Michael F Jobling, Joni D Mott, +8 authors, Monica T Finnegan, Vladimir Jurukovski, Anna C Erickson, Peter J Walian, Scott E Taylor, Steven Ledbetter, Catherine M Lawrence, Daniel B Rifkin, Mary Helen Barcellos-Hoff. less Radiat Res, 2006 Dec 08; 166(6). PMID: 17149983
|
The intersection of radiotherapy and immunotherapy: mechanisms and clinical implications. Michael Spiotto, Yang-Xin Fu, Ralph R Weichselbaum. Sci Immunol, 2016 Dec 27; 1(3). PMID: 28018989 Free PMC article.
|
Radiotherapy-Mediated Immunomodulation and Anti-Tumor Abscopal Effect Combining Immune Checkpoint Blockade. Xinrui Zhao, Chunlin Shao. Cancers (Basel), 2020 Oct 01; 12(10). PMID: 32992835 Free PMC article. Review.
|
Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer. Scott J Antonia, Augusto Villegas, +28 authors, Davey Daniel, David Vicente, Shuji Murakami, Rina Hui, Takashi Yokoi, Alberto Chiappori, Ki H Lee, Maike de Wit, Byoung C Cho, Maryam Bourhaba, Xavier Quantin, Takaaki Tokito, Tarek Mekhail, David Planchard, Young-Chul Kim, Christos S Karapetis, Sandrine Hiret, Gyula Ostoros, Kaoru Kubota, Jhanelle E Gray, Luis Paz-Ares, Javier de Castro Carpeño, Catherine Wadsworth, Giovanni Melillo, Haiyi Jiang, Yifan Huang, Phillip A Dennis, Mustafa Özgüroğlu, PACIFIC Investigators. less N Engl J Med, 2017 Sep 09; 377(20). PMID: 28885881 Highly Cited.
|
Consensus guidelines for the definition, detection and interpretation of immunogenic cell death. Lorenzo Galluzzi, Ilio Vitale, +51 authors, Sarah Warren, Sandy Adjemian, Patrizia Agostinis, Aitziber Buqué Martinez, Timothy A Chan, George Coukos, Sandra Demaria, Eric Deutsch, Dobrin Draganov, Richard L Edelson, Silvia C Formenti, Jitka Fucikova, Lucia Gabriele, Udo S Gaipl, Sofia R Gameiro, Abhishek D Garg, Encouse Golden, Jian Han, Kevin J Harrington, Akseli Hemminki, James W Hodge, Dewan Md Sakib Hossain, Tim Illidge, Michael Karin, Howard L Kaufman, Oliver Kepp, Guido Kroemer, Juan Jose Lasarte, Sherene Loi, Michael T Lotze, Gwenola Manic, Taha Merghoub, Alan A Melcher, Karen L Mossman, Felipe Prosper, Øystein Rekdal, Maria Rescigno, Chiara Riganti, Antonella Sistigu, Mark J Smyth, Radek Spisek, John Stagg, Bryan E Strauss, Daolin Tang, Kazuki Tatsuno, Stefaan W van Gool, Peter Vandenabeele, Takahiro Yamazaki, Dmitriy Zamarin, Laurence Zitvogel, Alessandra Cesano, Francesco M Marincola. less J Immunother Cancer, 2020 Mar 27; 8(1). PMID: 32209603 Free PMC article. Review.
|
Low-Dose Radiation Conditioning Enables CAR T Cells to Mitigate Antigen Escape. Carl DeSelm, M Lia Palomba, +4 authors, Joachim Yahalom, Mohamad Hamieh, Justin Eyquem, Vinagolu K Rajasekhar, Michel Sadelain. less Mol Ther, 2018 Nov 13; 26(11). PMID: 30415658 Free PMC article.
|
Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas. Jennifer E Kim, Mira A Patel, +23 authors, Antonella Mangraviti, Eileen S Kim, Debebe Theodros, Esteban Velarde, Ann Liu, Eric W Sankey, Ada Tam, Haiying Xu, Dimitrios Mathios, Christopher M Jackson, Sarah Harris-Bookman, Tomas Garzon-Muvdi, Mary Sheu, Allison M Martin, Betty M Tyler, Phuoc T Tran, Xiaobu Ye, Alessandro Olivi, Janis M Taube, Peter C Burger, Charles G Drake, Henry Brem, Drew M Pardoll, Michael Lim. less Clin Cancer Res, 2016 Jul 01; 23(1). PMID: 27358487 Free PMC article. Highly Cited.
|
Radiotherapy as a Backbone for Novel Concepts in Cancer Immunotherapy. Julijan Kabiljo, Felix Harpain, Sebastian Carotta, Michael Bergmann. Cancers (Basel), 2020 Jan 08; 12(1). PMID: 31905723 Free PMC article. Review.
|
Intrapatient dose escalation of anti-CTLA-4 antibody in patients with metastatic melanoma. Ajay V Maker, James C Yang, +11 authors, Richard M Sherry, Suzanne L Topalian, Udai S Kammula, Richard E Royal, Marybeth Hughes, Michael J Yellin, Leah R Haworth, Catherine Levy, Tamika Allen, Sharon A Mavroukakis, Peter Attia, Steven A Rosenberg. less J Immunother, 2006 Jun 27; 29(4). PMID: 16799341 Free PMC article.
|
Absolute Lymphocyte Count Predicts Abscopal Responses and Outcomes in Patients Receiving Combined Immunotherapy and Radiation Therapy: Analysis of 3 Phase 1/2 Trials. Dawei Chen, Vivek Verma, +3 authors, Roshal R Patel, Hampartsoum B Barsoumian, Maria Angelica Cortez, James W Welsh. less Int J Radiat Oncol Biol Phys, 2020 Feb 10; 108(1). PMID: 32036004
|
Stereotactic radiosurgery for melanoma brain metastases in patients receiving ipilimumab: safety profile and efficacy of combined treatment. Ana P Kiess, Jedd D Wolchok, +6 authors, Christopher A Barker, Michael A Postow, Viviane Tabar, Jason T Huse, Timothy A Chan, Yoshiya Yamada, Kathryn Beal. less Int J Radiat Oncol Biol Phys, 2015 Mar 11; 92(2). PMID: 25754629 Free PMC article. Highly Cited.
|
Complete Local and Abscopal Responses from a Combination of Radiation and Nivolumab in Refractory Hodgkin's Lymphoma. Qian Qin, Xinyu Nan, +9 authors, Tara Miller, Ronald Fisher, Bin Teh, Shruti Pandita, Andrew M Farach, Sai Ravi Pingali, Raj K Pandita, E Brian Butler, Tej K Pandita, Swaminathan P Iyer. less Radiat Res, 2018 Jun 28; 190(3). PMID: 29949442 Free PMC article.
|
The antitumor immune response generated by fractionated radiation therapy may be limited by tumor cell adaptive resistance and can be circumvented by PD-L1 blockade. S J Dovedi, T M Illidge. Oncoimmunology, 2015 Jul 04; 4(7). PMID: 26140246 Free PMC article.
|
Safety and Efficacy of Pembrolizumab With Chemoradiotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma: A Phase IB Study. Steven F Powell, Kathryn A Gold, +15 authors, Mark M Gitau, Christopher J Sumey, Michele M Lohr, Steven C McGraw, Ryan K Nowak, Ashley W Jensen, Miran J Blanchard, Christopher D Fischer, Julie Bykowski, Christie A Ellison, Lora J Black, Paul A Thompson, Juan L Callejas-Valera, John H Lee, Ezra E W Cohen, William C Spanos. less J Clin Oncol, 2020 Jun 02; 38(21). PMID: 32479189 Free PMC article.
|
Phase 1 Trial of Pembrolizumab Administered Concurrently With Chemoradiotherapy for Locally Advanced Non-Small Cell Lung Cancer: A Nonrandomized Controlled Trial. Salma K Jabbour, Abigail T Berman, +9 authors, Roy H Decker, Yong Lin, Steven J Feigenberg, Scott N Gettinger, Charu Aggarwal, Corey J Langer, Charles B Simone, Jeffrey D Bradley, Joseph Aisner, Jyoti Malhotra. less JAMA Oncol, 2020 Feb 23; 6(6). PMID: 32077891 Free PMC article.
|
Radiation and immunotherapy: a synergistic combination. Anusha Kalbasi, Carl H June, Naomi Haas, Neha Vapiwala. J Clin Invest, 2013 Jul 19; 123(7). PMID: 23863633 Free PMC article. Highly Cited.
|
TGFβ Is a Master Regulator of Radiation Therapy-Induced Antitumor Immunity. Claire Vanpouille-Box, Julie M Diamond, +5 authors, Karsten A Pilones, Jiri Zavadil, James S Babb, Silvia C Formenti, Mary Helen Barcellos-Hoff, Sandra Demaria. less Cancer Res, 2015 Apr 11; 75(11). PMID: 25858148 Free PMC article. Highly Cited.
|
Anti-PD-1 immunotherapy in combination with sequential involved-site radiotherapy in heavily pretreated refractory Hodgkin lymphoma. L Quéro, L Gilardin, +6 authors, I Fumagalli, V Martin, S Guillerm, O Bauduceau, Y M Kirova, C Hennequin, P Brice. less Cancer Radiother, 2019 Feb 09; 23(2). PMID: 30733172
|
Immunogenic cell death in cancer therapy: Present and emerging inducers. Jingyi Zhou, Gangyang Wang, +3 authors, Yinze Chen, Hongxia Wang, Yingqi Hua, Zhengdong Cai. less J Cell Mol Med, 2019 Jun 19; 23(8). PMID: 31210425 Free PMC article. Highly Cited. Review.
|
Radiotherapy and immunotherapy: a beneficial liaison? Ralph R Weichselbaum, Hua Liang, Liufu Deng, Yang-Xin Fu. Nat Rev Clin Oncol, 2017 Jan 18; 14(6). PMID: 28094262 Highly Cited. Review.
|
Radiation as an immunological adjuvant: current evidence on dose and fractionation. Sandra Demaria, Silvia C Formenti. Front Oncol, 2012 Nov 01; 2. PMID: 23112958 Free PMC article. Highly Cited.
|
Whole body irradiation; radiobiology or medicine? R H MOLE. Br J Radiol, 1953 May 01; 26(305). PMID: 13042090 Highly Cited.
|
Toxicity in combination immune checkpoint inhibitor and radiation therapy: A systematic review and meta-analysis. Congzhou M Sha, Eric J Lehrer, +4 authors, Clara Hwang, Daniel M Trifiletti, Heath B Mackley, Joseph J Drabick, Nicholas G Zaorsky. less Radiother Oncol, 2020 Jul 28; 151. PMID: 32717359 Systematic Review.
|
The molecular machinery of regulated cell death. Daolin Tang, Rui Kang, +2 authors, Tom Vanden Berghe, Peter Vandenabeele, Guido Kroemer. less Cell Res, 2019 Apr 06; 29(5). PMID: 30948788 Free PMC article. Highly Cited. Review.
|
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors. Liufu Deng, Hua Liang, +12 authors, Meng Xu, Xuanming Yang, Byron Burnette, Ainhoa Arina, Xiao-Dong Li, Helena Mauceri, Michael Beckett, Thomas Darga, Xiaona Huang, Thomas F Gajewski, Zhijian J Chen, Yang-Xin Fu, Ralph R Weichselbaum. less Immunity, 2014 Dec 18; 41(5). PMID: 25517616 Free PMC article. Highly Cited.
|
Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1. Cecilia Roux, Soode Moghadas Jafari, +14 authors, Rahul Shinde, Gordon Duncan, David W Cescon, Jennifer Silvester, Mandy F Chu, Kelsey Hodgson, Thorsten Berger, Andrew Wakeham, Luis Palomero, Mar Garcia-Valero, Miguel A Pujana, Tak W Mak, Tracy L McGaha, Paola Cappello, Chiara Gorrini. less Proc Natl Acad Sci U S A, 2019 Feb 17; 116(10). PMID: 30770442 Free PMC article.
|
TGFβ Blockade Enhances Radiotherapy Abscopal Efficacy Effects in Combination with Anti-PD1 and Anti-CD137 Immunostimulatory Monoclonal Antibodies. María E Rodríguez-Ruiz, Inmaculada Rodríguez, +12 authors, Lina Mayorga, Tania Labiano, Benigno Barbes, Iñaki Etxeberria, Mariano Ponz-Sarvise, Arantza Azpilikueta, Elixabet Bolaños, Miguel F Sanmamed, Pedro Berraondo, Felipe A Calvo, Mary Helen Barcelos-Hoff, Jose L Perez-Gracia, Ignacio Melero. less Mol Cancer Ther, 2019 Jan 27; 18(3). PMID: 30683810
|
Concurrent radiotherapy and ipilimumab immunotherapy for patients with melanoma. Christopher A Barker, Michael A Postow, +5 authors, Shaheer A Khan, Kathryn Beal, Preeti K Parhar, Yoshiya Yamada, Nancy Y Lee, Jedd D Wolchok. less Cancer Immunol Res, 2014 Apr 30; 1(2). PMID: 24777500 Free PMC article. Review.
|
Abscopal Effects of Radiotherapy Are Enhanced by Combined Immunostimulatory mAbs and Are Dependent on CD8 T Cells and Crosspriming. María E Rodriguez-Ruiz, Inmaculada Rodriguez, +13 authors, Saray Garasa, Benigno Barbes, Jose Luis Solorzano, Jose Luis Perez-Gracia, Sara Labiano, Miguel F Sanmamed, Arantza Azpilikueta, Elixabet Bolaños, Alfonso R Sanchez-Paulete, M Angela Aznar, Ana Rouzaut, Kurt A Schalper, Maria Jure-Kunkel, Ignacio Melero. less Cancer Res, 2016 Aug 24; 76(20). PMID: 27550452 Highly Cited.
|
Three-Year Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC-Update from PACIFIC. Jhanelle E Gray, Augusto Villegas, +17 authors, Davey Daniel, David Vicente, Shuji Murakami, Rina Hui, Takayasu Kurata, Alberto Chiappori, Ki Hyeong Lee, Byoung Chul Cho, David Planchard, Luis Paz-Ares, Corinne Faivre-Finn, Johan F Vansteenkiste, David R Spigel, Catherine Wadsworth, Maria Taboada, Phillip A Dennis, Mustafa Özgüroğlu, Scott J Antonia. less J Thorac Oncol, 2019 Oct 18; 15(2). PMID: 31622733 Free PMC article.
|
Relationship between pneumonitis induced by immune checkpoint inhibitors and the underlying parenchymal status: a retrospective study. Chiara Pozzessere, Hasna Bouchaab, +7 authors, Raphael Jumeau, Igor Letovanec, Cécile Daccord, Jean Bourhis, John O Prior, Solange Peters, Romain Lazor, Catherine Beigelman-Aubry. less ERJ Open Res, 2020 Mar 24; 6(1). PMID: 32201690 Free PMC article.
|
Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies. Inge Verbrugge, Jim Hagekyriakou, +8 authors, Leslie L Sharp, Mara Galli, Alison West, Nicole M McLaughlin, Hélène Duret, Hideo Yagita, Ricky W Johnstone, Mark J Smyth, Nicole M Haynes. less Cancer Res, 2012 May 10; 72(13). PMID: 22570253 Highly Cited.
|
Pembrolizumab After Completion of Locally Ablative Therapy for Oligometastatic Non-Small Cell Lung Cancer: A Phase 2 Trial. Joshua M Bauml, Rosemarie Mick, +11 authors, Christine Ciunci, Charu Aggarwal, Christiana Davis, Tracey Evans, Charuhas Deshpande, Linda Miller, Pooja Patel, Evan Alley, Christina Knepley, Faith Mutale, Roger B Cohen, Corey J Langer. less JAMA Oncol, 2019 Jul 12; 5(9). PMID: 31294762 Free PMC article. Highly Cited.
|
Timing and type of immune checkpoint therapy affect the early radiographic response of melanoma brain metastases to stereotactic radiosurgery. Jack M Qian, James B Yu, Harriet M Kluger, Veronica L S Chiang. Cancer, 2016 Jun 11; 122(19). PMID: 27285122 Free PMC article. Highly Cited.
|
Immunogenic cell death in cancer therapy. Guido Kroemer, Lorenzo Galluzzi, Oliver Kepp, Laurence Zitvogel. Annu Rev Immunol, 2012 Nov 20; 31. PMID: 23157435 Highly Cited. Review.
|
A meta-analysis of the abscopal effect in preclinical models: Is the biologically effective dose a relevant physical trigger? Raffaella Marconi, Silvia Strolin, Gianluca Bossi, Lidia Strigari. PLoS One, 2017 Feb 22; 12(2). PMID: 28222111 Free PMC article.
|
A Prospective Clinical Trial Combining Radiation Therapy With Systemic Immunotherapy in Metastatic Melanoma. Susan M Hiniker, Sunil A Reddy, +6 authors, Holden T Maecker, Priyanka B Subrahmanyam, Yael Rosenberg-Hasson, Susan M Swetter, Saurabh Saha, Lei Shura, Susan J Knox. less Int J Radiat Oncol Biol Phys, 2016 Sep 30; 96(3). PMID: 27681753 Free PMC article. Highly Cited.
|
Immunotherapy and stereotactic ablative radiotherapy (ISABR): a curative approach? Michael B Bernstein, Sunil Krishnan, James W Hodge, Joe Y Chang. Nat Rev Clin Oncol, 2016 Mar 10; 13(8). PMID: 26951040 Free PMC article. Highly Cited. Review.
|
Safety of combining radiotherapy with immune-checkpoint inhibition. William L Hwang, Luke R G Pike, +2 authors, Trevor J Royce, Brandon A Mahal, Jay S Loeffler. less Nat Rev Clin Oncol, 2018 Jun 07; 15(8). PMID: 29872177 Highly Cited. Review.
|
Ipilimumab with Stereotactic Ablative Radiation Therapy: Phase I Results and Immunologic Correlates from Peripheral T Cells. Chad Tang, James W Welsh, +17 authors, Patricia de Groot, Erminia Massarelli, Joe Y Chang, Kenneth R Hess, Sreyashi Basu, Michael A Curran, Maria E Cabanillas, Vivek Subbiah, Siqing Fu, Apostolia M Tsimberidou, Daniel Karp, Daniel R Gomez, Adi Diab, Ritsuko Komaki, John V Heymach, Padmanee Sharma, Aung Naing, David S Hong. less Clin Cancer Res, 2016 Nov 01; 23(6). PMID: 27649551 Free PMC article. Highly Cited.
|
Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice. Liufu Deng, Hua Liang, +4 authors, Byron Burnette, Michael Beckett, Thomas Darga, Ralph R Weichselbaum, Yang-Xin Fu. less J Clin Invest, 2014 Jan 03; 124(2). PMID: 24382348 Free PMC article. Highly Cited.
|
Combining radiotherapy and cancer immunotherapy: a paradigm shift. Silvia C Formenti, Sandra Demaria. J Natl Cancer Inst, 2013 Jan 08; 105(4). PMID: 23291374 Free PMC article. Highly Cited. Review.
|
DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity. Claire Vanpouille-Box, Amandine Alard, +7 authors, Molykutty J Aryankalayil, Yasmeen Sarfraz, Julie M Diamond, Robert J Schneider, Giorgio Inghirami, C Norman Coleman, Silvia C Formenti, Sandra Demaria. less Nat Commun, 2017 Jun 10; 8. PMID: 28598415 Free PMC article. Highly Cited.
|
Impact of immunotherapy among patients with melanoma brain metastases managed with radiotherapy. William A Stokes, David C Binder, +4 authors, Bernard L Jones, Ayman J Oweida, Arthur K Liu, Chad G Rusthoven, Sana D Karam. less J Neuroimmunol, 2017 Nov 21; 313. PMID: 29153603
|
Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody. M Zahidunnabi Dewan, Ashley E Galloway, +4 authors, Noriko Kawashima, J Keith Dewyngaert, James S Babb, Silvia C Formenti, Sandra Demaria. less Clin Cancer Res, 2009 Aug 27; 15(17). PMID: 19706802 Free PMC article. Highly Cited.
|
Overall Survival with Durvalumab after Chemoradiotherapy in Stage III NSCLC. Scott J Antonia, Augusto Villegas, +31 authors, Davey Daniel, David Vicente, Shuji Murakami, Rina Hui, Takayasu Kurata, Alberto Chiappori, Ki H Lee, Maike de Wit, Byoung C Cho, Maryam Bourhaba, Xavier Quantin, Takaaki Tokito, Tarek Mekhail, David Planchard, Young-Chul Kim, Christos S Karapetis, Sandrine Hiret, Gyula Ostoros, Kaoru Kubota, Jhanelle E Gray, Luis Paz-Ares, Javier de Castro Carpeño, Corinne Faivre-Finn, Martin Reck, Johan Vansteenkiste, David R Spigel, Catherine Wadsworth, Giovanni Melillo, Maria Taboada, Phillip A Dennis, Mustafa Özgüroğlu, PACIFIC Investigators. less N Engl J Med, 2018 Oct 04; 379(24). PMID: 30280658 Highly Cited.
|
Concurrent radiotherapy for patients with metastatic melanoma and receiving anti-programmed-death 1 therapy: a safe and effective combination. Amélie Aboudaram, Anouchka Modesto, +8 authors, Léonor Chaltiel, Carlos Gomez-Roca, Serge Boulinguez, Vincent Sibaud, Jean-Pierre Delord, Ciprian Chira, Martine Delannes, Elizabeth Moyal, Nicolas Meyer. less Melanoma Res, 2017 Sep 01; 27(5). PMID: 28858075
|
Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial. Encouse B Golden, Arpit Chhabra, +9 authors, Abraham Chachoua, Sylvia Adams, Martin Donach, Maria Fenton-Kerimian, Kent Friedman, Fabio Ponzo, James S Babb, Judith Goldberg, Sandra Demaria, Silvia C Formenti. less Lancet Oncol, 2015 Jun 23; 16(7). PMID: 26095785 Highly Cited.
|
GM-CSF and ipilimumab therapy in metastatic melanoma: Clinical outcomes and immunologic responses. Serena S Kwek, James Kahn, +8 authors, Samantha K Greaney, Jera Lewis, Edward Cha, Li Zhang, Robert W Weber, Lonnie Leonard, Svetomir N Markovic, Lawrence Fong, Lynn E Spitler. less Oncoimmunology, 2016 May 04; 5(4). PMID: 27141383 Free PMC article.
|
A phase 2 trial of consolidation pembrolizumab following concurrent chemoradiation for patients with unresectable stage III non-small cell lung cancer: Hoosier Cancer Research Network LUN 14-179. Greg A Durm, Salma K Jabbour, +15 authors, Sandra K Althouse, Ziyue Liu, Ahad A Sadiq, Robin T Zon, Shadia I Jalal, Goetz H Kloecker, Michael J Williamson, Karen L Reckamp, Robert M Langdon, Ebenezer A Kio, Ryan D Gentzler, Bamidele A Adesunloye, Wael A Harb, Radhika V Walling, Michael L Titzer, Nasser H Hanna. less Cancer, 2020 Jul 23; 126(19). PMID: 32697352
|
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Lionel Apetoh, François Ghiringhelli, +25 authors, Antoine Tesniere, Michel Obeid, Carla Ortiz, Alfredo Criollo, Grégoire Mignot, M Chiara Maiuri, Evelyn Ullrich, Patrick Saulnier, Huan Yang, Sebastian Amigorena, Bernard Ryffel, Franck J Barrat, Paul Saftig, Francis Levi, Rosette Lidereau, Catherine Nogues, Jean-Paul Mira, Agnès Chompret, Virginie Joulin, Françoise Clavel-Chapelon, Jean Bourhis, Fabrice André, Suzette Delaloge, Thomas Tursz, Guido Kroemer, Laurence Zitvogel. less Nat Med, 2007 Aug 21; 13(9). PMID: 17704786 Highly Cited.
|
Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): a prospective cohort study. Gilles R Dagenais, Darryl P Leong, +29 authors, Sumathy Rangarajan, Fernando Lanas, Patricio Lopez-Jaramillo, Rajeev Gupta, Rafael Diaz, Alvaro Avezum, Gustavo B F Oliveira, Andreas Wielgosz, Shameena R Parambath, Prem Mony, Khalid F Alhabib, Ahmet Temizhan, Noorhassim Ismail, Jephat Chifamba, Karen Yeates, Rasha Khatib, Omar Rahman, Katarzyna Zatonska, Khawar Kazmi, Li Wei, Jun Zhu, Annika Rosengren, K Vijayakumar, Manmeet Kaur, Viswanathan Mohan, AfzalHussein Yusufali, Roya Kelishadi, Koon K Teo, Philip Joseph, Salim Yusuf. less Lancet, 2019 Sep 08; 395(10226). PMID: 31492501 Highly Cited.
|
Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy. Kristina H Young, Jason R Baird, +9 authors, Talicia Savage, Benjamin Cottam, David Friedman, Shelly Bambina, David J Messenheimer, Bernard Fox, Pippa Newell, Keith S Bahjat, Michael J Gough, Marka R Crittenden. less PLoS One, 2016 Jun 10; 11(6). PMID: 27281029 Free PMC article. Highly Cited.
|
Elective Nodal Irradiation Attenuates the Combinatorial Efficacy of Stereotactic Radiation Therapy and Immunotherapy. Ariel E Marciscano, Ali Ghasemzadeh, +18 authors, Thomas R Nirschl, Debebe Theodros, Christina M Kochel, Brian J Francica, Yuki Muroyama, Robert A Anders, Andrew B Sharabi, Esteban Velarde, Wendy Mao, Kunal R Chaudhary, Matthew G Chaimowitz, John Wong, Mark J Selby, Kent B Thudium, Alan J Korman, David Ulmert, Daniel L J Thorek, Theodore L DeWeese, Charles G Drake. less Clin Cancer Res, 2018 Jun 15; 24(20). PMID: 29898992 Free PMC article.
|
Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated. Sandra Demaria, Bruce Ng, +4 authors, Mary Louise Devitt, James S Babb, Noriko Kawashima, Leonard Liebes, Silvia C Formenti. less Int J Radiat Oncol Biol Phys, 2004 Feb 18; 58(3). PMID: 14967443 Highly Cited.
|
Combined radiotherapy with nivolumab for extracranial metastatic malignant melanoma. Tetsuya Komatsu, Kenta Konishi, +2 authors, Masahiro Aoshima, Yoshiki Tokura, Katsumasa Nakamura. less Jpn J Radiol, 2018 Sep 13; 36(12). PMID: 30206802
|
Optimising efficacy and reducing toxicity of anticancer radioimmunotherapy. Eric Deutsch, Cyrus Chargari, Lorenzo Galluzzi, Guido Kroemer. Lancet Oncol, 2019 Aug 01; 20(8). PMID: 31364597 Review.
|
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer. Christina Twyman-Saint Victor, Andrew J Rech, +22 authors, Amit Maity, Ramesh Rengan, Kristen E Pauken, Erietta Stelekati, Joseph L Benci, Bihui Xu, Hannah Dada, Pamela M Odorizzi, Ramin S Herati, Kathleen D Mansfield, Dana Patsch, Ravi K Amaravadi, Lynn M Schuchter, Hemant Ishwaran, Rosemarie Mick, Daniel A Pryma, Xiaowei Xu, Michael D Feldman, Tara C Gangadhar, Stephen M Hahn, E John Wherry, Robert H Vonderheide, Andy J Minn. less Nature, 2015 Mar 11; 520(7547). PMID: 25754329 Free PMC article. Highly Cited.
|
A Prospective, Phase 1 Trial of Nivolumab, Ipilimumab, and Radiotherapy in Patients with Advanced Melanoma. Michael A Postow, Susan J Knox, +22 authors, Debra A Goldman, Yuval Elhanati, Vikram Mavinkurve, Phillip Wong, Darragh Halpenny, Sunil K Reddy, Kenya Vado, Danielle McCabe, Kristen Aufiero Ramirez, Mary Macri, Paul Schwarzenberger, Toni Ricciardi, Aileen Ryan, Ralph Venhaus, Parisa Momtaz, Alexander N Shoushtari, Margaret K Callahan, Paul B Chapman, Jedd D Wolchok, Priyanka B Subrahmanyam, Holden T Maecker, Katherine S Panageas, Christopher A Barker. less Clin Cancer Res, 2020 Mar 25; 26(13). PMID: 32205463 Free PMC article.
|
TGFβ1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo. Fanny Bouquet, Anupama Pal, +8 authors, Karsten A Pilones, Sandra Demaria, Byron Hann, Rosemary J Akhurst, Jim S Babb, Scott M Lonning, J Keith DeWyngaert, Silvia C Formenti, Mary Helen Barcellos-Hoff. less Clin Cancer Res, 2011 Oct 27; 17(21). PMID: 22028490 Free PMC article.
|
Immune Priming of the Tumor Microenvironment by Radiation. Wen Jiang, Charles K Chan, +2 authors, Irving L Weissman, Betty Y S Kim, Stephen M Hahn. less Trends Cancer, 2017 Jul 26; 2(11). PMID: 28741502 Review.
|
Phase 1 study of stereotactic body radiotherapy and interleukin-2--tumor and immunological responses. Steven K Seung, Brendan D Curti, +8 authors, Marka Crittenden, Edwin Walker, Todd Coffey, Janet C Siebert, William Miller, Roxanne Payne, Lyn Glenn, Alexandru Bageac, Walter J Urba. less Sci Transl Med, 2012 Jun 08; 4(137). PMID: 22674552 Highly Cited.
|
Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial. Eugene D Kwon, Charles G Drake, +24 authors, Howard I Scher, Karim Fizazi, Alberto Bossi, Alfons J M van den Eertwegh, Michael Krainer, Nadine Houede, Ricardo Santos, Hakim Mahammedi, Siobhan Ng, Michele Maio, Fabio A Franke, Santhanam Sundar, Neeraj Agarwal, Andries M Bergman, Tudor E Ciuleanu, Ernesto Korbenfeld, Lisa Sengeløv, Steinbjorn Hansen, Christopher Logothetis, Tomasz M Beer, M Brent McHenry, Paul Gagnier, David Liu, Winald R Gerritsen, CA184-043 Investigators. less Lancet Oncol, 2014 May 17; 15(7). PMID: 24831977 Free PMC article. Highly Cited.
|
Previous radiotherapy and the clinical activity and toxicity of pembrolizumab in the treatment of non-small-cell lung cancer: a secondary analysis of the KEYNOTE-001 phase 1 trial. Narek Shaverdian, Aaron E Lisberg, +5 authors, Krikor Bornazyan, Darlene Veruttipong, Jonathan W Goldman, Silvia C Formenti, Edward B Garon, Percy Lee. less Lancet Oncol, 2017 May 30; 18(7). PMID: 28551359 Free PMC article. Highly Cited.
|
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma. Tyler R Simpson, Fubin Li, +11 authors, Welby Montalvo-Ortiz, Manuel A Sepulveda, Katharina Bergerhoff, Frederick Arce, Claire Roddie, Jake Y Henry, Hideo Yagita, Jedd D Wolchok, Karl S Peggs, Jeffrey V Ravetch, James P Allison, Sergio A Quezada. less J Exp Med, 2013 Jul 31; 210(9). PMID: 23897981 Free PMC article. Highly Cited.
|
Chimeric antigen receptor T-cell therapy - assessment and management of toxicities. Sattva S Neelapu, Sudhakar Tummala, +16 authors, Partow Kebriaei, William Wierda, Cristina Gutierrez, Frederick L Locke, Krishna V Komanduri, Yi Lin, Nitin Jain, Naval Daver, Jason Westin, Alison M Gulbis, Monica E Loghin, John F de Groot, Sherry Adkins, Suzanne E Davis, Katayoun Rezvani, Patrick Hwu, Elizabeth J Shpall. less Nat Rev Clin Oncol, 2017 Sep 20; 15(1). PMID: 28925994 Free PMC article. Highly Cited. Review.
|
Acquired resistance to fractionated radiotherapy can be overcome by concurrent PD-L1 blockade. Simon J Dovedi, Amy L Adlard, +11 authors, Grazyna Lipowska-Bhalla, Conor McKenna, Sherrie Jones, Eleanor J Cheadle, Ian J Stratford, Edmund Poon, Michelle Morrow, Ross Stewart, Hazel Jones, Robert W Wilkinson, Jamie Honeychurch, Tim M Illidge. less Cancer Res, 2014 Oct 03; 74(19). PMID: 25274032 Highly Cited.
|
Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication. Ruth Ganss, Eduard Ryschich, +2 authors, Ernst Klar, Bernd Arnold, Günter J Hämmerling. less Cancer Res, 2002 Mar 13; 62(5). PMID: 11888921 Highly Cited.
|
Lost in Translation: Deciphering the Mechanism of Action of Anti-human CTLA-4. Sergio A Quezada, Karl S Peggs. Clin Cancer Res, 2018 Oct 07; 25(4). PMID: 30291135
|
Integrative Analysis Identifies a Novel AXL-PI3 Kinase-PD-L1 Signaling Axis Associated with Radiation Resistance in Head and Neck Cancer. Heath D Skinner, Uma Giri, +15 authors, Liang P Yang, Manish Kumar, Ying Liu, Michael D Story, Curtis R Pickering, Lauren A Byers, Michelle D Williams, Jing Wang, Li Shen, Suk Y Yoo, You Hong Fan, David P Molkentine, Beth M Beadle, Raymond E Meyn, Jeffrey N Myers, John V Heymach. less Clin Cancer Res, 2017 May 10; 23(11). PMID: 28476872 Free PMC article.
|
Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors. Jonathan M Pitt, Marie Vétizou, +8 authors, Romain Daillère, María Paula Roberti, Takahiro Yamazaki, Bertrand Routy, Patricia Lepage, Ivo Gomperts Boneca, Mathias Chamaillard, Guido Kroemer, Laurence Zitvogel. less Immunity, 2016 Jun 23; 44(6). PMID: 27332730 Highly Cited. Review.
|
Immune Modulation of Head and Neck Squamous Cell Carcinoma and the Tumor Microenvironment by Conventional Therapeutics. Sayuri Miyauchi, Sangwoo S Kim, +6 authors, John Pang, Kathryn A Gold, J Silvio Gutkind, Joseph A Califano, Loren K Mell, Ezra E W Cohen, Andrew B Sharabi. less Clin Cancer Res, 2019 Mar 01; 25(14). PMID: 30814108 Free PMC article. Review.
|
Clinical outcomes of melanoma brain metastases treated with stereotactic radiation and anti-PD-1 therapy. K A Ahmed, D G Stallworth, +7 authors, Y Kim, P A S Johnstone, L B Harrison, J J Caudell, H H M Yu, A B Etame, J S Weber, G T Gibney. less Ann Oncol, 2015 Dec 30; 27(3). PMID: 26712903 Highly Cited.
|
Modern Radiotherapy Concepts and the Impact of Radiation on Immune Activation. Lisa Deloch, Anja Derer, +3 authors, Josefin Hartmann, Benjamin Frey, Rainer Fietkau, Udo S Gaipl. less Front Oncol, 2016 Jul 06; 6. PMID: 27379203 Free PMC article. Highly Cited. Review.
|
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Lorenzo Galluzzi, Ilio Vitale, +166 authors, Stuart A Aaronson, John M Abrams, Dieter Adam, Patrizia Agostinis, Emad S Alnemri, Lucia Altucci, Ivano Amelio, David W Andrews, Margherita Annicchiarico-Petruzzelli, Alexey V Antonov, Eli Arama, Eric H Baehrecke, Nickolai A Barlev, Nicolas G Bazan, Francesca Bernassola, Mathieu J M Bertrand, Katiuscia Bianchi, Mikhail V Blagosklonny, Klas Blomgren, Christoph Borner, Patricia Boya, Catherine Brenner, Michelangelo Campanella, Eleonora Candi, Didac Carmona-Gutierrez, Francesco Cecconi, Francis K-M Chan, Navdeep S Chandel, Emily H Cheng, Jerry E Chipuk, John A Cidlowski, Aaron Ciechanover, Gerald M Cohen, Marcus Conrad, Juan R Cubillos-Ruiz, Peter E Czabotar, Vincenzo D'Angiolella, Ted M Dawson, Valina L Dawson, Vincenzo De Laurenzi, Ruggero De Maria, Klaus-Michael Debatin, Ralph J DeBerardinis, Mohanish Deshmukh, Nicola Di Daniele, Francesco Di Virgilio, Vishva M Dixit, Scott J Dixon, Colin S Duckett, Brian D Dynlacht, Wafik S El-Deiry, John W Elrod, Gian Maria Fimia, Simone Fulda, Ana J García-Sáez, Abhishek D Garg, Carmen Garrido, Evripidis Gavathiotis, Pierre Golstein, Eyal Gottlieb, Douglas R Green, Lloyd A Greene, Hinrich Gronemeyer, Atan Gross, Gyorgy Hajnoczky, J Marie Hardwick, Isaac S Harris, Michael O Hengartner, Claudio Hetz, Hidenori Ichijo, Marja Jäättelä, Bertrand Joseph, Philipp J Jost, Philippe P Juin, William J Kaiser, Michael Karin, Thomas Kaufmann, Oliver Kepp, Adi Kimchi, Richard N Kitsis, Daniel J Klionsky, Richard A Knight, Sharad Kumar, Sam W Lee, John J Lemasters, Beth Levine, Andreas Linkermann, Stuart A Lipton, Richard A Lockshin, Carlos López-Otín, Scott W Lowe, Tom Luedde, Enrico Lugli, Marion MacFarlane, Frank Madeo, Michal Malewicz, Walter Malorni, Gwenola Manic, Jean-Christophe Marine, Seamus J Martin, Jean-Claude Martinou, Jan Paul Medema, Patrick Mehlen, Pascal Meier, Sonia Melino, Edward A Miao, Jeffery D Molkentin, Ute M Moll, Cristina Muñoz-Pinedo, Shigekazu Nagata, Gabriel Nuñez, Andrew Oberst, Moshe Oren, Michael Overholtzer, Michele Pagano, Theocharis Panaretakis, Manolis Pasparakis, Josef M Penninger, David M Pereira, Shazib Pervaiz, Marcus E Peter, Mauro Piacentini, Paolo Pinton, Jochen H M Prehn, Hamsa Puthalakath, Gabriel A Rabinovich, Markus Rehm, Rosario Rizzuto, Cecilia M P Rodrigues, David C Rubinsztein, Thomas Rudel, Kevin M Ryan, Emre Sayan, Luca Scorrano, Feng Shao, Yufang Shi, John Silke, Hans-Uwe Simon, Antonella Sistigu, Brent R Stockwell, Andreas Strasser, Gyorgy Szabadkai, Stephen W G Tait, Daolin Tang, Nektarios Tavernarakis, Andrew Thorburn, Yoshihide Tsujimoto, Boris Turk, Tom Vanden Berghe, Peter Vandenabeele, Matthew G Vander Heiden, Andreas Villunger, Herbert W Virgin, Karen H Vousden, Domagoj Vucic, Erwin F Wagner, Henning Walczak, David Wallach, Ying Wang, James A Wells, Will Wood, Junying Yuan, Zahra Zakeri, Boris Zhivotovsky, Laurence Zitvogel, Gerry Melino, Guido Kroemer. less Cell Death Differ, 2018 Jan 25; 25(3). PMID: 29362479 Free PMC article. Highly Cited. Review.
|
Radiation enhances regulatory T cell representation. Evelyn L Kachikwu, Keisuke S Iwamoto, +5 authors, Yu-Pei Liao, John J DeMarco, Nzhde Agazaryan, James S Economou, William H McBride, Dörthe Schaue. less Int J Radiat Oncol Biol Phys, 2010 Nov 26; 81(4). PMID: 21093169 Free PMC article.
|
Radiosurgery for melanoma brain metastases in the ipilimumab era and the possibility of longer survival. Jonathan P S Knisely, James B Yu, +3 authors, Jaclyn Flanigan, Mario Sznol, Harriet M Kluger, Veronica L S Chiang. less J Neurosurg, 2012 Jun 19; 117(2). PMID: 22702482 Free PMC article. Highly Cited.
|
NCCN Guidelines Insights: Non-Small Cell Lung Cancer, Version 1.2020. David S Ettinger, Douglas E Wood, +34 authors, Charu Aggarwal, Dara L Aisner, Wallace Akerley, Jessica R Bauman, Ankit Bharat, Debora S Bruno, Joe Y Chang, Lucian R Chirieac, Thomas A D'Amico, Thomas J Dilling, Michael Dobelbower, Scott Gettinger, Ramaswamy Govindan, Matthew A Gubens, Mark Hennon, Leora Horn, Rudy P Lackner, Michael Lanuti, Ticiana A Leal, Jules Lin, Billy W Loo, Renato G Martins, Gregory A Otterson, Sandip P Patel, Karen L Reckamp, Gregory J Riely, Steven E Schild, Theresa A Shapiro, James Stevenson, Scott J Swanson, Kurt W Tauer, Stephen C Yang, Kristina Gregory, OCN, Miranda Hughes. less J Natl Compr Canc Netw, 2019 Dec 06; 17(12). PMID: 31805526 Highly Cited.
|
Potential and unsolved problems of anti-PD-1/PD-L1 therapy combined with radiotherapy. Yiyi Cao, Wenbo Li, ZhengJie Wang, Hua Pang. Tumori, 2020 Aug 01; 107(4). PMID: 32734832 Review.
|
Transforming growth factor beta inhibits the antigen-presenting functions and antitumor activity of dendritic cell vaccines. James J Kobie, Rita S Wu, +6 authors, Robert A Kurt, Sunming Lou, Miranda K Adelman, Luke J Whitesell, Lalitha V Ramanathapuram, Carlos L Arteaga, Emmanuel T Akporiaye. less Cancer Res, 2003 Apr 19; 63(8). PMID: 12702574
|
Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. Eric A Reits, James W Hodge, +14 authors, Carla A Herberts, Tom A Groothuis, Mala Chakraborty, Elizabeth K Wansley, Kevin Camphausen, Rosalie M Luiten, Arnold H de Ru, Joost Neijssen, Alexander Griekspoor, Elly Mesman, Frank A Verreck, Hergen Spits, Jeffrey Schlom, Peter van Veelen, Jacques J Neefjes. less J Exp Med, 2006 Apr 26; 203(5). PMID: 16636135 Free PMC article. Highly Cited.
|
Is the Combination of Immunotherapy and Radiotherapy in Non-small Cell Lung Cancer a Feasible and Effective Approach? Mathieu Spaas, Yolande Lievens. Front Med (Lausanne), 2019 Dec 04; 6. PMID: 31788476 Free PMC article. Review.
|
Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor. Amit A Lugade, James P Moran, +3 authors, Scott A Gerber, Robert C Rose, John G Frelinger, Edith M Lord. less J Immunol, 2005 Jun 10; 174(12). PMID: 15944250 Highly Cited.
|
PD-1 Restrains Radiotherapy-Induced Abscopal Effect. Sean S Park, Haidong Dong, +7 authors, Xin Liu, Susan M Harrington, Christopher J Krco, Michael P Grams, Aaron S Mansfield, Keith M Furutani, Kenneth R Olivier, Eugene D Kwon. less Cancer Immunol Res, 2015 Feb 24; 3(6). PMID: 25701325 Free PMC article. Highly Cited.
|
Tolerance and outcomes of stereotactic radiosurgery combined with anti-programmed cell death-1 (pembrolizumab) for melanoma brain metastases. Charlee Nardin, Christine Mateus, +5 authors, Mathieu Texier, Emilie Lanoy, Salima Hibat-Allah, Samy Ammari, Caroline Robert, Frederic Dhermain. less Melanoma Res, 2018 Jan 23; 28(2). PMID: 29356789
|
A systematic review of the influence of radiation-induced lymphopenia on survival outcomes in solid tumors. Bhanu Prasad Venkatesulu, Supriya Mallick, Steven H Lin, Sunil Krishnan. Crit Rev Oncol Hematol, 2018 Feb 28; 123. PMID: 29482778 Highly Cited. Systematic Review.
|
Maximizing tumor immunity with fractionated radiation. Dörthe Schaue, Josephine A Ratikan, Keisuke S Iwamoto, William H McBride. Int J Radiat Oncol Biol Phys, 2012 Jan 03; 83(4). PMID: 22208977 Free PMC article. Highly Cited.
|