Journal Article
. 1986 Aug; 315(9):559-63.
doi: 10.1056/NEJM198608283150906.

The relation between survival and age at diagnosis in breast cancer

H O Adami  B Malker  L Holmberg  I Persson  B Stone  
  • PMID: 3736639
  •     115 citations

Abstract

We analyzed the relation between age at diagnosis and relative survival (ratio of observed to expected survival) in 57,068 women in Sweden in whom breast cancer was diagnosed in 1960 to 1978 (about 98 percent of all cases). Women who were 45 to 49 years old had the best prognosis, with a relative survival exceeding that of the youngest patients (less than 30 years) by 7.6 to 12.9 percent at different periods of observation. Relative survival declined markedly after the age of 49--particularly in women aged 50 to 59--and the oldest women (greater than 75) had the worst rate. The difference in relative survival between those older than 75 and those 45 to 49 increased from 8.6 percent at 2 years to 12.2, 20.3, and 27.5 percent after 5, 10, and 15 years of follow-up, respectively. The long-term annual mortality rate due to breast cancer approached 1 to 2 percent at the premenopausal ages but exceeded 5 percent throughout the period of observation in the oldest age group. An understanding of the biologic basis for the complex relation between age and prognosis might provide a better understanding of the natural history of breast cancer in women.

Proportional hazards and recursive partitioning and amalgamation analyses of the Southwest Oncology Group node-positive adjuvant CMFVP breast cancer data base: a pilot study.
K S Albain, S Green, +3 authors, C K Osborne.
Breast Cancer Res Treat, 1992 Jan 01; 22(3). PMID: 1391993
Long-term consequences of estrogen and estrogen-progestin replacement.
H O Adami.
Cancer Causes Control, 1992 Jan 01; 3(1). PMID: 1536919
Breast cancer data collection for surgical audit.
W G Woods, R J Earlam.
Ann R Coll Surg Engl, 1991 Nov 01; 73(6). PMID: 1759766    Free PMC article.
Histological features, DNA content and prognosis of breast carcinoma found incidentally or in screening.
H Joensuu, S Toikkanen, P J Klemi.
Br J Cancer, 1991 Sep 01; 64(3). PMID: 1911203    Free PMC article.
Breast cancer incidence and prevalence estimated from survival and mortality.
R Capocaccia, A Verdecchia, +3 authors, F Berrino.
Cancer Causes Control, 1990 Jul 01; 1(1). PMID: 2102272
A prognostic score in histological node negative breast cancer.
B Chevallier, V Mosseri, +3 authors, B Asselain.
Br J Cancer, 1990 Mar 01; 61(3). PMID: 2328212    Free PMC article.
Season of tumour detection influences factors predicting survival of patients with breast cancer.
B H Mason, I M Holdaway, +2 authors, R G Kay.
Breast Cancer Res Treat, 1990 Jan 01; 15(1). PMID: 2328328
Do treatment protocols improve end results? A study of survival of patients with multiple myeloma in Finland.
S Karjalainen, I Palva.
BMJ, 1989 Oct 28; 299(6707). PMID: 2511967    Free PMC article.
The Swedish two county trial of mammographic screening for breast cancer: recent results and calculation of benefit.
L Tabar, G Fagerberg, S W Duffy, N E Day.
J Epidemiol Community Health, 1989 Jun 01; 43(2). PMID: 2512366    Free PMC article.
The biology and natural history of breast cancer from the screening perspective.
L Holmberg, J Pontén, H O Adami.
World J Surg, 1989 Jan 01; 13(1). PMID: 2658349
Review.
Risk factors and 10-year breast cancer survival in northern Alberta.
A W Lees, H J Jenkins, +3 authors, J Hanson.
Breast Cancer Res Treat, 1989 Mar 01; 13(2). PMID: 2730961
Prognosis in bilateral breast cancer. Effects of time interval between first and second primary tumours.
L Holmberg, H O Adami, +3 authors, A Lindgren.
Br J Cancer, 1988 Aug 01; 58(2). PMID: 3166909    Free PMC article.
Elective cancer education: how effective from the public health viewpoint?
C H Gray, J S Colome, J R Curry-Daly.
Am J Public Health, 1987 Sep 01; 77(9). PMID: 3618856    Free PMC article.
Breast cancer in the elderly.
M Bellet, C Alonso, B Ojeda.
Postgrad Med J, 1995 Nov 01; 71(841). PMID: 7494769    Free PMC article.
Review.
Improved survival in young women with breast cancer.
B O Anderson, R T Senie, +3 authors, P I Borgen.
Ann Surg Oncol, 1995 Sep 01; 2(5). PMID: 7496835
Incompleteness of oral cancer registration in south-east England, 1971-87.
K A Warnakulasuriya, P Acworth, J Bell, N W Johnson.
Br J Cancer, 1994 Oct 01; 70(4). PMID: 7917931    Free PMC article.
Survival of breast cancer patients from Piedmont, Italy.
P Boffetta, F Merletti, +3 authors, B Terracini.
Cancer Causes Control, 1993 May 01; 4(3). PMID: 8318637
Review.
Hormone replacement therapy and breast cancer mortality in Swedish women: results after adjustment for 'healthy drug-user' effect.
J Yuen, I Persson, +3 authors, H O Adami.
Cancer Causes Control, 1993 Jul 01; 4(4). PMID: 8394149
Prognostic value of steroid receptors after long-term follow-up of 2257 operable breast cancers.
M F Pichon, P Broet, +8 authors, B Asselain.
Br J Cancer, 1996 Jun 01; 73(12). PMID: 8664127    Free PMC article.
Breast carcinomas occurring in young women (< 35 years) are different.
R A Walker, E Lees, M B Webb, S J Dearing.
Br J Cancer, 1996 Dec 01; 74(11). PMID: 8956795    Free PMC article.
A population-based survival study on female breast cancer in Madras, India.
C K Gajalakshmi, V Shanta, +2 authors, R J Black.
Br J Cancer, 1997 Jan 01; 75(5). PMID: 9043040    Free PMC article.
Mammographic screening in older women. Is it worthwhile?
J A van Dijck, M J Broeders, A L Verbeek.
Drugs Aging, 1997 Feb 01; 10(2). PMID: 9061265
Review.
Body weight and vascular invasion in post-menopausal women with breast cancer.
R A Badwe, I S Fentiman, R R Millis, W M Gregory.
Br J Cancer, 1997 Jan 01; 75(6). PMID: 9062415    Free PMC article.
Role of age as a prognostic factor in breast cancer.
A Tsuchiya, R Abe, +4 authors, I Kimijima.
Surg Today, 1997 Jan 01; 27(3). PMID: 9068100
Early-onset breast cancer--histopathological and prognostic considerations.
J Kollias, C W Elston, +2 authors, R W Blamey.
Br J Cancer, 1997 Jan 01; 75(9). PMID: 9155052    Free PMC article.
Treating breast cancer during pregnancy. What can be taken safely?
M Espié, C Cuvier.
Drug Saf, 1998 Mar 26; 18(2). PMID: 9512920
Review.
Hospital volume differences and five-year survival from breast cancer.
P J Roohan, N A Bickell, +3 authors, A L Siu.
Am J Public Health, 1998 Mar 31; 88(3). PMID: 9518982    Free PMC article.
Frequent allelic losses at 11q24.1-q25 in young women with breast cancer: association with poor survival.
M Gentile, K Olsen, M Dufmats, S Wingren.
Br J Cancer, 1999 Jun 09; 80(5-6). PMID: 10360664    Free PMC article.
Factors influencing the effect of age on prognosis in breast cancer: population based study.
N Kroman, M B Jensen, +3 authors, M Melbye.
BMJ, 2000 Mar 04; 320(7233). PMID: 10678859    Free PMC article.
Tamoxifen as the primary treatment in elderly patients with breast cancer.
S B Hooper, A D K Hill, +4 authors, N O'Higgins.
Ir J Med Sci, 2002 May 08; 171(1). PMID: 11993590
Relation between the rate of tumour cell proliferation and latency time in radiation associated breast cancer.
H Olsson, B Baldetorp, M Fernö, R Perfekt.
BMC Cancer, 2003 Apr 17; 3. PMID: 12697074    Free PMC article.
Pregnancy and breast cancer: a population-based study.
W Reed, E Hannisdal, +3 authors, J M Nesland.
Virchows Arch, 2003 May 21; 443(1). PMID: 12756565
Do younger women with non-metastatic and non-inflammatory breast carcinoma have poor prognosis?
Aleyamma Mathew, Manoj Pandey, Balakrishnan Rajan.
World J Surg Oncol, 2004 Jan 23; 2. PMID: 14736343    Free PMC article.
Prognostic value of morphology and hormone receptor status in breast cancer - a population-based study.
C Allemani, M Sant, +16 authors, E M I Williams.
Br J Cancer, 2004 Sep 15; 91(7). PMID: 15365566    Free PMC article.
Young age: an independent risk factor for disease-free survival in women with operable breast cancer.
Wonshik Han, Seok Won Kim, +6 authors, Dong-Young Noh.
BMC Cancer, 2004 Nov 18; 4. PMID: 15546499    Free PMC article.
Modeling the effect of age in T1-2 breast cancer using the SEER database.
Patricia Tai, Gábor Cserni, +6 authors, Guy Storme.
BMC Cancer, 2005 Oct 11; 5. PMID: 16212670    Free PMC article.
Confirmation of double-peaked time distribution of mortality among Asian breast cancer patients in a population-based study.
Fei Gao, Say Beng Tan, David Machin, Nan Soon Wong.
Breast Cancer Res, 2007 Mar 08; 9(2). PMID: 17341292    Free PMC article.
Treatment of premenopausal women with early breast cancer: old challenges and new opportunities.
Stefan Aebi, Olivia Pagani.
Drugs, 2007 Jun 30; 67(10). PMID: 17600388
Review.
Age-specific differences in oncogenic pathway deregulation seen in human breast tumors.
Carey K Anders, Chaitanya R Acharya, +11 authors, Anil Potti.
PLoS One, 2008 Jan 03; 3(1). PMID: 18167534    Free PMC article.
Expression profile of BRCA1 and BRCA2 genes in premenopausal Mexican women with breast cancer: clinical and immunohistochemical correlates.
Gloria Loredo-Pozos, Erwin Chiquete, +3 authors, Martha E Ramos-Márquez.
Med Oncol, 2008 Nov 18; 26(3). PMID: 19012002
Is the prognosis of young patients with hepatocellular carcinoma poorer than the prognosis of older patients? A comparative analysis of clinical characteristics, prognostic features, and survival outcome.
Pik-Eu Chang, Wai-Choung Ong, Hock-Foong Lui, Chee-Kiat Tan.
J Gastroenterol, 2008 Nov 18; 43(11). PMID: 19012042
Elevated breast cancer mortality in women younger than age 40 years compared with older women is attributed to poorer survival in early-stage disease.
Jennifer L Gnerlich, Anjali D Deshpande, +3 authors, Julie A Margenthaler.
J Am Coll Surg, 2009 Mar 26; 208(3). PMID: 19317994    Free PMC article.
Highly Cited.
Breast cancer before age 40 years.
Carey K Anders, Rebecca Johnson, +2 authors, Archie Bleyer.
Semin Oncol, 2009 May 23; 36(3). PMID: 19460581    Free PMC article.
Highly Cited. Review.
Breast cancer in young women: poor survival despite intensive treatment.
Hanna Fredholm, Sonja Eaker, +3 authors, Henrik Lindman.
PLoS One, 2009 Nov 13; 4(11). PMID: 19907646    Free PMC article.
Highly Cited.
Association of invasion-promoting tenascin-C additional domains with breast cancers in young women.
David S Guttery, Rachael A Hancox, +6 authors, Jacqueline A Shaw.
Breast Cancer Res, 2010 Aug 04; 12(4). PMID: 20678196    Free PMC article.
Age-related variation in the relationship between menopausal hormone therapy and the risk of dying from breast cancer.
Kerryn W Reding, David R Doody, +5 authors, Kathleen E Malone.
Breast Cancer Res Treat, 2010 Sep 30; 126(3). PMID: 20878463    Free PMC article.
Breast cancer in moroccan young women: a retrospective study.
Halima Abahssain, Issam Lalya, +8 authors, Hassan Errihani.
BMC Res Notes, 2010 Nov 10; 3. PMID: 21059204    Free PMC article.
Population-based mammography screening below age 50: balancing radiation-induced vs prevented breast cancer deaths.
R de Gelder, G Draisma, E A M Heijnsdijk, H J de Koning.
Br J Cancer, 2011 Mar 03; 104(7). PMID: 21364575    Free PMC article.
Use of tamoxifen and aromatase inhibitors in a large population-based cohort of women with breast cancer.
L Huiart, S Dell'Aniello, S Suissa.
Br J Cancer, 2011 Apr 28; 104(10). PMID: 21522148    Free PMC article.
The effect of age on delay in diagnosis and stage of breast cancer.
Ann H Partridge, Melissa E Hughes, +8 authors, Rulla M Tamimi.
Oncologist, 2012 May 05; 17(6). PMID: 22554997    Free PMC article.
A comparative analysis of hepatocellular carcinoma after hepatic resection in young versus elderly patients.
Cho Rok Lee, Jin Hong Lim, +5 authors, Kyung Sik Kim.
J Gastrointest Surg, 2012 Jul 20; 16(9). PMID: 22810298
Expression of E-Cadherin in breast carcinomas and its association with other biological markers - a prospective study.
Chintamani, B Rekhi, +2 authors, S Saxena.
Indian J Surg Oncol, 2010 Jan 01; 1(1). PMID: 22930617    Free PMC article.
Debate: The biology of breast cancer in young women is unique.
Marco Colleoni, Carey K Anders.
Oncologist, 2013 May 02; 18(4). PMID: 23633450    Free PMC article.
Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women.
Dilek Colak, Asmaa Nofal, +11 authors, Suad M Bin Amer.
PLoS One, 2013 May 25; 8(5). PMID: 23704896    Free PMC article.
Epidemiology and prognosis of breast cancer in young women.
Hussein A Assi, Katia E Khoury, +3 authors, Nagi S El Saghir.
J Thorac Dis, 2013 Jul 03; 5 Suppl 1. PMID: 23819024    Free PMC article.
Highly Cited.
Breast cancer survival in Germany: a population-based high resolution study from Saarland.
Bernd Holleczek, Lina Jansen, Hermann Brenner.
PLoS One, 2013 Aug 13; 8(7). PMID: 23936237    Free PMC article.
Perceptions, knowledge, and satisfaction with contralateral prophylactic mastectomy among young women with breast cancer: a cross-sectional survey.
Shoshana M Rosenberg, Michaela S Tracy, +9 authors, Ann H Partridge.
Ann Intern Med, 2013 Sep 18; 159(6). PMID: 24042365    Free PMC article.
Long-term impact of the 70-gene signature on breast cancer outcome.
C A Drukker, H van Tinteren, +4 authors, L J Van't Veer.
Breast Cancer Res Treat, 2014 Jan 22; 143(3). PMID: 24445566    Free PMC article.
Establishment and characterization of two primary breast cancer cell lines from young Indian breast cancer patients: mutation analysis.
Santhi Latha Pandrangi, Sarangadhara Appala Raju Bagadi, +10 authors, Sunita Saxena.
Cancer Cell Int, 2014 Feb 08; 14(1). PMID: 24502646    Free PMC article.
Breast and cervical screening by race/ethnicity: comparative analyses before and during the Great Recession.
Christopher J King, Jie Chen, Mary A Garza, Stephen B Thomas.
Am J Prev Med, 2014 Mar 22; 46(4). PMID: 24650838    Free PMC article.
Distinct breast cancer subtypes in women with early-onset disease across races.
Mandeep Singh, Yi Ding, +16 authors, Peng Lee.
Am J Cancer Res, 2014 Jul 25; 4(4). PMID: 25057437    Free PMC article.
A four-long non-coding RNA signature in predicting breast cancer survival.
Jin Meng, Ping Li, +2 authors, Shen Fu.
J Exp Clin Cancer Res, 2014 Oct 08; 33. PMID: 25288503    Free PMC article.
Highly Cited.
Temporal trend, clinicopathologic and sociodemographic characterization of age at diagnosis of breast cancer among US women diagnosed from 1990 to 2009.
Gabriel Escarela, Luis Carlos Pérez-Ruiz, Gabriel Núñez-Antonio.
Springerplus, 2014 Nov 14; 3. PMID: 25392796    Free PMC article.
Impact of age on the survival of patients with liver cancer: an analysis of 27,255 patients in the SEER database.
Wenjie Zhang, Beicheng Sun.
Oncotarget, 2015 Jan 13; 6(2). PMID: 25575810    Free PMC article.
Optimal management of breast cancer in the elderly patient: current perspectives.
Olivia Le Saux, Bertrand Ripamonti, +4 authors, Claire Falandry.
Clin Interv Aging, 2015 Jan 23; 10. PMID: 25609933    Free PMC article.
Review.
An evaluation of the prognostic model PREDICT using the POSH cohort of women aged ⩽40 years at breast cancer diagnosis.
T Maishman, E Copson, +7 authors, D Eccles.
Br J Cancer, 2015 Feb 13; 112(6). PMID: 25675148    Free PMC article.
Incidence and overall survival of malignant ameloblastoma.
Alexandra Rizzitelli, Nicolas R Smoll, +2 authors, David J Hunter-Smith.
PLoS One, 2015 Feb 19; 10(2). PMID: 25692490    Free PMC article.
The predictive accuracy of PREDICT: a personalized decision-making tool for Southeast Asian women with breast cancer.
Hoong-Seam Wong, Shridevi Subramaniam, +7 authors, Nirmala Bhoo-Pathy.
Medicine (Baltimore), 2015 Feb 26; 94(8). PMID: 25715267    Free PMC article.
Age at diagnosis in relation to survival following breast cancer: a cohort study.
Jasmine Brandt, Jens Peter Garne, Ingrid Tengrup, Jonas Manjer.
World J Surg Oncol, 2015 Apr 19; 13. PMID: 25889186    Free PMC article.
Breast cancer in 30-year-old or younger patients: clinicopathologic characteristics and prognosis.
Yongqiang Yao, Mingqian Cao, Hong Fang, JiPing Xie.
World J Surg Oncol, 2015 Apr 19; 13. PMID: 25889848    Free PMC article.
Breast cancer in ethnically different populations.
Vani Parmar, Akshita Singh.
South Asian J Cancer, 2015 May 21; 4(2). PMID: 25992359    Free PMC article.
Molecular Phenotype of Breast Cancer According to Time Since Last Pregnancy in a Large Cohort of Young Women.
Laura C Collins, Shari Gelber, +12 authors, Ann H Partridge.
Oncologist, 2015 May 31; 20(7). PMID: 26025931    Free PMC article.
The prognosis of hepatocellular carcinoma after curative hepatectomy in young patients.
Sang Yun Ha, Insuk Sohn, +2 authors, Cheol-Keun Park.
Oncotarget, 2015 Jun 21; 6(21). PMID: 26093092    Free PMC article.
Different patterns in the prognostic value of age for bladder cancer-specific survival depending on tumor stages.
Huan Feng, Wei Zhang, Jiajun Li, Xiaozhe Lu.
Am J Cancer Res, 2015 Aug 14; 5(6). PMID: 26269768    Free PMC article.
Fertility preservation in reproductive-age women facing gonadotoxic treatments.
J Roberts, R Ronn, N Tallon, H Holzer.
Curr Oncol, 2015 Aug 25; 22(4). PMID: 26300680    Free PMC article.
Reproductive factors and hormone receptor status among very young (<35 years) breast cancer patients.
Xiaoqing Jia, Guangyu Liu, +3 authors, Zhimin Shao.
Oncotarget, 2015 Aug 26; 6(27). PMID: 26304928    Free PMC article.
Quantitative Gene Expression by Recurrence Score in ER-Positive Breast Cancer, by Age.
Sandra M Swain, Raquel Nunes, +2 authors, Amy P Sing.
Adv Ther, 2015 Nov 28; 32(12). PMID: 26610382    Free PMC article.
Utility of Red Cell Distribution Width as a Prognostic Factor in Young Breast Cancer Patients.
Du-Ping Huang, Rui-Min Ma, You-Qun Xiang.
Medicine (Baltimore), 2016 Apr 29; 95(17). PMID: 27124030    Free PMC article.
Young Age Is Associated with Increased Locoregional Recurrence in Node-Positive Breast Cancer with Luminal Subtypes.
Sang-Won Kim, Mison Chun, +5 authors, Seung Hee Kang.
Cancer Res Treat, 2016 Aug 25; 49(2). PMID: 27554479    Free PMC article.
Long-term outcome in young women with breast cancer: a population-based study.
Hanna Fredholm, Kristina Magnusson, +8 authors, Irma Fredriksson.
Breast Cancer Res Treat, 2016 Sep 15; 160(1). PMID: 27624330    Free PMC article.
African American Race is an Independent Risk Factor in Survival from Initially Diagnosed Localized Breast Cancer.
Robert Wieder, Basit Shafiq, Nabil Adam.
J Cancer, 2016 Oct 05; 7(12). PMID: 27698895    Free PMC article.
Yellow fever vaccine 17D administered to healthy women aged between 40 and 54 years halves breast cancer risk: an observational study.
Giuseppe Mastrangelo, Sofia Pavanello, +2 authors, Ugo Fedeli.
Eur J Cancer Prev, 2016 Nov 22; 27(4). PMID: 27870643    Free PMC article.
Breast cancer in neurofibromatosis type 1: overrepresentation of unfavourable prognostic factors.
Elina Uusitalo, Roope A Kallionpää, +9 authors, Juha Peltonen.
Br J Cancer, 2016 Dec 09; 116(2). PMID: 27931045    Free PMC article.
Relationship of Social Determinants of Health with the Three-year Survival Rate of Breast Cancer
Esmat Davoudi Monfared, Maryam Mohseny, +3 authors, Mohammad Ali Heidarnia.
Asian Pac J Cancer Prev, 2017 May 27; 18(4). PMID: 28547951    Free PMC article.
Hepatocellular carcinoma in elderly: Clinical characteristics, treatments and outcomes compared with younger adults.
Hui Guo, Tao Wu, +5 authors, Xu-Feng Zhang.
PLoS One, 2017 Sep 09; 12(9). PMID: 28886106    Free PMC article.
Physician peer group characteristics and timeliness of breast cancer surgery.
Jacqueline Bachand, Pamela R Soulos, +4 authors, Cary P Gross.
Breast Cancer Res Treat, 2018 Apr 26; 170(3). PMID: 29693229    Free PMC article.
Wild-type p53 upregulates an early onset breast cancer-associated gene GAS7 to suppress metastasis via GAS7-CYFIP1-mediated signaling pathway.
Jer-Wei Chang, Wen-Hung Kuo, +19 authors, Lu-Hai Wang.
Oncogene, 2018 May 01; 37(30). PMID: 29706651    Free PMC article.
Age distribution and outcomes in patients undergoing breast cancer resection in Saudi Arabia. A single-institute study.
Balqis Alabdulkarim, Mazen Hassanain, +2 authors, Hana Alkarji.
Saudi Med J, 2018 May 09; 39(5). PMID: 29738005    Free PMC article.
Cancer incidence and mortality in Medellin-Colombia, 2010-2014.
Mary Ruth Brome Bohórquez, Diego Mauricio Montoya Restrepo, Liseth Amell.
Colomb Med (Cali), 2018 Jul 10; 49(1). PMID: 29983467    Free PMC article.
Impact of p53 arg72pro SNP on Breast Cancer Risk in North Indian Population.
Naseem Akhter, Sajad A Dar, +9 authors, Syed Akhtar Husain.
Curr Genomics, 2018 Aug 02; 19(5). PMID: 30065615    Free PMC article.
Association Analysis of Somatic Copy Number Alteration Burden With Breast Cancer Survival.
Linfan Zhang, Nikta Feizi, Chen Chi, Pingzhao Hu.
Front Genet, 2018 Oct 20; 9. PMID: 30337938    Free PMC article.
Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer.
Marcus Vetter, Julia Landin, +13 authors, Nicola Aceto.
Breast Cancer Res, 2018 Nov 22; 20(1). PMID: 30458879    Free PMC article.
Clinical Features and Outcomes of Invasive Breast Cancer: Age-Specific Analysis of a Modern Hospital-Based Registry.
Ji-Yeon Kim, Danbee Kang, +9 authors, Yeon Hee Park.
J Glob Oncol, 2019 Jul 02; 5. PMID: 31260394    Free PMC article.
Breast Cancer Diagnostic Delays Among Young Mexican Women Are Associated With a Lack of Suspicion by Health Care Providers at First Presentation.
Karla Unger-Saldaña, Kenneth Fitch-Picos, Cynthia Villarreal-Garza.
J Glob Oncol, 2019 Jul 25; 5. PMID: 31335236    Free PMC article.
Diffusion-Weighted Imaging of Breast Cancer: Correlation of the Apparent Diffusion Coefficient Value with Pathologic Prognostic Factors.
Şehnaz Tezcan, Nihal Uslu, +2 authors, Tugan Tezcaner.
Eur J Breast Health, 2019 Oct 18; 15(4). PMID: 31620686    Free PMC article.
Hormone Therapy and Factors Affecting Fertility of Women Under 50-Year-Old with Breast Cancer.
Mehdi Moradinazar, Behjat Marzbani, +3 authors, Zeinab Moradinazar.
Breast Cancer (Dove Med Press), 2020 Jan 11; 11. PMID: 31920374    Free PMC article.
How ageing processes influence cancer.
João Pedro de Magalhães.
Nat Rev Cancer, 2013 Apr 25; 13(5). PMID: 23612461
Highly Cited. Review.
Study of Gene Expression Profiles of Breast Cancers in Indian Women.
Shreshtha Malvia, Sarangadhara Appala Raju Bagadi, +5 authors, Sunita Saxena.
Sci Rep, 2019 Jul 12; 9(1). PMID: 31292488    Free PMC article.
Prognostic Value of Skeletal Muscle Depletion Measured on Computed Tomography for Overall Survival in Patients with Non-Metastatic Breast Cancer.
Jimi Huh, Bumhee Park, +6 authors, Tae Hee Kim.
J Breast Cancer, 2020 Mar 07; 23(1). PMID: 32140272    Free PMC article.
Prognostic Value of the Progesterone Receptor by Subtype in Patients with Estrogen Receptor-Positive, HER-2 Negative Breast Cancer.
Kathleen Van Asten, Laurence Slembrouck, +16 authors, Patrick Neven.
Oncologist, 2018 Sep 02; 24(2). PMID: 30171067    Free PMC article.
Prognosis in young women less than 40 years of age with brain metastasis from breast cancer.
A Mustillo, J P Ayoub, +2 authors, M Florescu.
Curr Oncol, 2020 Mar 29; 27(1). PMID: 32218659    Free PMC article.
Greater Survival Improvement in African American vs. Caucasian Women with Hormone Negative Breast Cancer.
Robert Wieder, Basit Shafiq, Nabil Adam.
J Cancer, 2020 Apr 01; 11(10). PMID: 32226499    Free PMC article.
Mortality After Breast Cancer Among Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study.
Chaya S Moskowitz, Joanne F Chou, +13 authors, Tara O Henderson.
J Clin Oncol, 2019 Jul 02; 37(24). PMID: 31260644    Free PMC article.
SALMON: Survival Analysis Learning With Multi-Omics Neural Networks on Breast Cancer.
Zhi Huang, Xiaohui Zhan, +8 authors, Kun Huang.
Front Genet, 2019 Mar 25; 10. PMID: 30906311    Free PMC article.
Prognoses, outcomes, and clinicopathological characteristics of very elderly patients with hepatocellular carcinoma who underwent hepatectomy.
Shingo Shimada, Toshiya Kamiyama, +5 authors, Akinobu Taketomi.
World J Surg Oncol, 2020 Jun 12; 18(1). PMID: 32522259    Free PMC article.
Clinical outcome of adjuvant radiotherapy for squamous cell carcinoma of the breast; a multicenter retrospective cohort study.
Mami Ogita, Kenshiro Shiraishi, +6 authors, Keiichi Nakagawa.
Breast, 2020 May 30; 52. PMID: 32470819    Free PMC article.
High Levels of Chromosomal Copy Number Alterations and TP53 Mutations Correlate with Poor Outcome in Younger Breast Cancer Patients.
Ayla Koçak, Kerstin Heselmeyer-Haddad, +13 authors, Thomas Ried.
Am J Pathol, 2020 May 18; 190(8). PMID: 32416097    Free PMC article.
GnRHa for Ovarian Protection and the Association between AMH and Ovarian Function during Adjuvant Chemotherapy for Breast Cancer.
Ying Zhong, Yan Lin, +11 authors, Qiang Sun.
J Cancer, 2019 Aug 16; 10(18). PMID: 31413747    Free PMC article.
Analysis of Clinicopathological Characteristics and Prognosis of Young Patients with Hepatocellular Carcinoma after Hepatectomy.
Chuan Li, Kang Chen, +9 authors, Le-Qun Li.
J Clin Transl Hepatol, 2020 Oct 22; 8(3). PMID: 33083251    Free PMC article.
Insights for the application of TILs and AR in the treatment of TNBC in routine clinical practice.
Agnese Losurdo, Rita De Sanctis, +9 authors, Armando Santoro.
Sci Rep, 2020 Nov 20; 10(1). PMID: 33208857    Free PMC article.
[Surgical treatment of intracranial meningiomas in Nouakchott, Mauritania].
Ahmed-Salem Kleib, Brahim Hamad Ngaidé, +4 authors, Outouma Soumaré.
Pan Afr Med J, 2019 May 01; 31. PMID: 31037206    Free PMC article.
Metabotropic glutamate receptor 1 is associated with unfavorable prognosis in ER-negative and triple-negative breast cancer.
Anna E M Bastiaansen, A Mieke Timmermans, +9 authors, Martijn M vanDuijn.
Sci Rep, 2020 Dec 20; 10(1). PMID: 33339858    Free PMC article.
Survival outcomes are associated with genomic instability in luminal breast cancers.
Lydia King, Andrew Flaus, Emma Holian, Aaron Golden.
PLoS One, 2021 Feb 04; 16(2). PMID: 33534788    Free PMC article.
Refining breast cancer prognosis by incorporating age at diagnosis into clinical prognostic staging: introduction of a novel online calculator.
Helen M Johnson, William Irish, Nasreen A Vohra, Jan H Wong.
Breast Cancer Res Treat, 2021 Feb 21; 187(3). PMID: 33609208
Clinicopathological characteristics and treatment of young women with breast cancer in China: a nationwide multicenter 10-year retrospective study.
Wei Zhang, Bai-Lin Zhang, +12 authors, Pin Zhang.
Gland Surg, 2021 Feb 27; 10(1). PMID: 33633974    Free PMC article.