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2,321,293 results (0.55 seconds)

Synthetic lethal therapies for cancer: what's next after PARP inhibitors?
Alan Ashworth, Christopher J Lord.
Nat Rev Clin Oncol. 2018 Jun 30; 15(9):564-576. PMID: 29955114
Highly Cited. Review.

Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer.
Juan R Cubillos-Ruiz, Sarah E Bettigole, Laurie H Glimcher.
Cell. 2017 Feb 12; 168(4):692-706. PMID: 28187289 Free PMC article
Highly Cited. Review.

Every step of the way: integrins in cancer progression and metastasis.
Hellyeh Hamidi, Johanna Ivaska.
Nat Rev Cancer. 2018 Jul 14; 18(9):533-548. PMID: 30002479 Free PMC article
Highly Cited. Review.

Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies.
Zsolt Sebestyen, Immo Prinz, +2 authors, Jurgen Kuball.
Nat Rev Drug Discov. 2019 Sep 06; 19(3):169-184. PMID: 31492944
Highly Cited. Review.

The promise and challenges of immune agonist antibody development in cancer.
Patrick A Mayes, Kenneth W Hance, Axel Hoos.
Nat Rev Drug Discov. 2018 Jun 15; 17(7):509-527. PMID: 29904196
Highly Cited. Review.

Extracellular vesicles in cancer - implications for future improvements in cancer care.
Rong Xu, Alin Rai, +3 authors, Richard J Simpson.
Nat Rev Clin Oncol. 2018 May 26; 15(10):617-638. PMID: 29795272
Highly Cited. Review.

The roles of DNA, RNA and histone methylation in ageing and cancer.
Ewa M Michalak, Marian L Burr, Andrew J Bannister, Mark A Dawson.
Nat Rev Mol Cell Biol. 2019 Jul 03; 20(10):573-589. PMID: 31270442
Highly Cited. Review.

Targeting B cell receptor signalling in cancer: preclinical and clinical advances.
Jan A Burger, Adrian Wiestner.
Nat Rev Cancer. 2018 Jan 19; 18(3):148-167. PMID: 29348577
Highly Cited. Review.

Epigenetic modulators, modifiers and mediators in cancer aetiology and progression.
Andrew P Feinberg, Michael A Koldobskiy, Anita Göndör.
Nat Rev Genet. 2016 Mar 14; 17(5):284-99. PMID: 26972587 Free PMC article
Highly Cited. Review.

The future of cancer treatment: immunomodulation, CARs and combination immunotherapy.
Danny N Khalil, Eric L Smith, Renier J Brentjens, Jedd D Wolchok.
Nat Rev Clin Oncol. 2016 Mar 15; 13(5):273-90. PMID: 26977780 Free PMC article
Highly Cited. Review.

Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond.
Michael Platten, Ellen A A Nollen, +2 authors, Christiane A Opitz.
Nat Rev Drug Discov. 2019 Feb 15; 18(5):379-401. PMID: 30760888
Highly Cited. Review.

A panoply of errors: polymerase proofreading domain mutations in cancer.
Emily Rayner, Inge C van Gool, +4 authors, David N Church.
Nat Rev Cancer. 2016 Jan 30; 16(2):71-81. PMID: 26822575
Highly Cited. Review.

New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer.
Anushka Dongre, Robert A Weinberg.
Nat Rev Mol Cell Biol. 2018 Nov 22; 20(2):69-84. PMID: 30459476
Highly Cited. Review.

The COSMIC Cancer Gene Census: describing genetic dysfunction across all human cancers.
Zbyslaw Sondka, Sally Bamford, +3 authors, Simon A Forbes.
Nat Rev Cancer. 2018 Oct 08; 18(11):696-705. PMID: 30293088 Free PMC article
Highly Cited. Review.

Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy.
Nisha Nagarsheth, Max S Wicha, Weiping Zou.
Nat Rev Immunol. 2017 May 30; 17(9):559-572. PMID: 28555670 Free PMC article
Highly Cited. Review.

A model for RAS mutation patterns in cancers: finding the sweet spot.
Siqi Li, Allan Balmain, Christopher M Counter.
Nat Rev Cancer. 2018 Nov 14; 18(12):767-777. PMID: 30420765
Highly Cited. Review.

Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy.
Silvia von Karstedt, Antonella Montinaro, Henning Walczak.
Nat Rev Cancer. 2017 May 26; 17(6):352-366. PMID: 28536452
Highly Cited. Review.

Endogenous DNA Damage as a Source of Genomic Instability in Cancer.
Anthony Tubbs, André Nussenzweig.
Cell. 2017 Feb 12; 168(4):644-656. PMID: 28187286 Free PMC article
Highly Cited. Review.

Functions of bromodomain-containing proteins and their roles in homeostasis and cancer.
Takao Fujisawa, Panagis Filippakopoulos.
Nat Rev Mol Cell Biol. 2017 Jan 05; 18(4):246-262. PMID: 28053347
Highly Cited. Review.

Dynamic versus static biomarkers in cancer immune checkpoint blockade: unravelling complexity.
W Joost Lesterhuis, Anthony Bosco, +3 authors, Richard A Lake.
Nat Rev Drug Discov. 2017 Jan 06; 16(4):264-272. PMID: 28057932
Highly Cited. Review.

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